# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Methyltransf_23 PF13489.6 KXG45112.1 - 2.6e-05 24.1 0.0 0.00013 21.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG45112.1 - 0.0001 22.9 0.0 0.00029 21.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG45112.1 - 0.0031 18.1 0.0 0.0082 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG45112.1 - 0.009 16.7 0.0 0.036 14.8 0.0 2.0 2 1 1 3 3 3 1 Methyltransferase domain AMP-binding_C PF13193.6 KXG45112.1 - 0.038 15.0 0.1 0.19 12.7 0.0 2.3 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 KXG45115.1 - 0.00012 21.5 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG45115.1 - 0.033 13.5 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase zf-RVT PF13966.6 KXG45116.1 - 0.12 13.1 0.9 0.2 12.4 0.2 1.8 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase F-box-like PF12937.7 KXG45117.1 - 0.0031 17.3 0.8 0.011 15.6 0.2 2.3 2 0 0 2 2 2 1 F-box-like NB-ARC PF00931.22 KXG45118.1 - 6.7e-06 25.5 0.0 9.9e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Glyco_hydro_71 PF03659.14 KXG45119.1 - 2.2e-119 398.7 4.8 2.6e-119 398.4 4.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.6 KXG45119.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Beta-lactamase PF00144.24 KXG45123.1 - 8.1e-59 199.5 0.0 9.1e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase DUF724 PF05266.14 KXG45124.1 - 0.0081 16.0 0.2 0.012 15.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF724) DUF2999 PF11212.8 KXG45124.1 - 0.061 13.6 0.0 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) T2SSF PF00482.23 KXG45124.1 - 0.95 9.4 2.7 1.8 8.6 1.1 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F APH PF01636.23 KXG45125.1 - 1.2e-12 48.3 0.0 3.4e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG45125.1 - 9.4e-08 31.9 0.0 4.4e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KXG45125.1 - 0.0091 15.4 0.0 0.39 10.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Fructosamin_kin PF03881.14 KXG45125.1 - 0.016 14.4 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase RIO1 PF01163.22 KXG45125.1 - 0.018 14.6 0.1 0.085 12.4 0.1 1.9 2 0 0 2 2 2 0 RIO1 family DDE_3 PF13358.6 KXG45126.1 - 3.5e-31 107.9 0.0 3.1e-30 104.9 0.0 2.2 2 1 1 3 3 3 1 DDE superfamily endonuclease DDE_1 PF03184.19 KXG45126.1 - 1.2e-05 25.1 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 KXG45126.1 - 2.8e-05 23.6 0.0 7.4e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix rve PF00665.26 KXG45126.1 - 0.0004 20.6 0.0 0.0017 18.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain HTH_32 PF13565.6 KXG45126.1 - 0.0025 18.4 0.0 0.077 13.6 0.0 2.7 1 1 1 2 2 2 1 Homeodomain-like domain Aminotran_1_2 PF00155.21 KXG45127.1 - 9.8e-40 136.8 0.0 1.2e-39 136.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MBOAT PF03062.19 KXG45129.1 - 3.5e-47 161.4 19.9 5.2e-47 160.9 19.9 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KXG45129.1 - 0.0078 16.5 2.0 0.021 15.1 2.0 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ABC_membrane PF00664.23 KXG45130.1 - 4.5e-89 298.7 40.9 1.3e-45 156.2 14.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXG45130.1 - 4.7e-63 211.8 0.0 5.7e-33 114.3 0.0 3.1 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXG45130.1 - 5.1e-15 55.5 3.9 8.6e-05 22.1 0.0 4.6 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXG45130.1 - 2.7e-09 37.4 0.2 0.0085 16.4 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KXG45130.1 - 1.7e-08 35.0 0.2 0.0008 19.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXG45130.1 - 2.4e-07 30.8 0.0 0.006 16.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KXG45130.1 - 3.2e-07 30.0 0.5 0.00073 19.2 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KXG45130.1 - 1.3e-06 28.5 0.5 0.95 9.2 0.0 3.9 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KXG45130.1 - 1.6e-06 28.1 0.0 0.017 14.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KXG45130.1 - 5.8e-06 26.8 1.3 1.8 9.0 0.0 4.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KXG45130.1 - 3.5e-05 24.4 4.8 0.27 11.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXG45130.1 - 4.5e-05 23.3 0.9 0.22 11.2 0.0 3.3 5 0 0 5 5 3 2 AAA domain Rad17 PF03215.15 KXG45130.1 - 7.4e-05 22.7 0.0 0.15 12.0 0.0 3.1 4 0 0 4 4 2 1 Rad17 P-loop domain AAA_7 PF12775.7 KXG45130.1 - 0.0001 21.8 0.0 0.57 9.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_5 PF07728.14 KXG45130.1 - 0.00014 21.9 0.0 0.57 10.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXG45130.1 - 0.0003 21.0 0.0 0.86 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXG45130.1 - 0.00047 20.7 0.0 0.97 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXG45130.1 - 0.00054 20.2 0.0 0.39 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXG45130.1 - 0.00058 19.5 0.0 0.98 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KXG45130.1 - 0.0019 18.0 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KXG45130.1 - 0.0025 18.0 3.3 1.2 9.4 0.2 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 KXG45130.1 - 0.0046 16.6 0.1 4.5 6.9 0.0 2.8 3 0 0 3 3 2 2 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 KXG45130.1 - 0.012 15.3 0.6 27 4.4 0.0 3.6 4 0 0 4 4 3 0 IstB-like ATP binding protein PRK PF00485.18 KXG45130.1 - 0.019 14.7 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 KXG45130.1 - 0.02 15.3 0.0 7.2 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 KXG45130.1 - 0.025 14.4 0.0 2.2 8.0 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 KXG45130.1 - 0.031 13.4 0.1 2.4 7.3 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain G-alpha PF00503.20 KXG45130.1 - 0.048 12.8 0.1 9.8 5.2 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit AAA_17 PF13207.6 KXG45130.1 - 0.07 13.5 0.2 26 5.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXG45130.1 - 0.072 12.5 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KXG45130.1 - 0.076 12.3 0.0 16 4.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin APS_kinase PF01583.20 KXG45130.1 - 0.11 12.3 0.0 7.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 KXG45130.1 - 0.12 12.4 0.2 31 4.7 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 KXG45130.1 - 2 8.0 4.0 22 4.6 0.0 3.0 4 0 0 4 4 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF21 PF01595.20 KXG45130.1 - 9.3 5.9 11.5 0.73 9.5 0.5 2.9 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain ubiquitin PF00240.23 KXG45133.1 - 0.00029 20.5 0.3 0.0019 17.9 0.1 2.2 1 1 1 2 2 2 1 Ubiquitin family SNF2_N PF00176.23 KXG45134.1 - 1.6e-25 89.6 0.0 4.7e-14 51.9 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KXG45134.1 - 3.5e-06 27.3 0.0 6.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG45134.1 - 0.00043 20.3 0.0 0.048 13.7 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit HATPase_c_3 PF13589.6 KXG45135.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4618 PF15397.6 KXG45136.1 - 0.0029 17.1 0.8 0.0039 16.7 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) ZapB PF06005.12 KXG45136.1 - 0.64 10.5 3.7 0.68 10.4 0.0 2.6 2 1 1 3 3 3 0 Cell division protein ZapB TMCO5 PF14992.6 KXG45137.1 - 0.0012 18.5 2.8 0.0015 18.2 2.8 1.1 1 0 0 1 1 1 1 TMCO5 family KLRAQ PF10205.9 KXG45137.1 - 0.0082 16.4 1.9 0.012 15.8 1.6 1.5 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein CEP63 PF17045.5 KXG45137.1 - 0.011 15.6 4.0 0.064 13.1 1.7 2.0 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa DUF16 PF01519.16 KXG45137.1 - 0.022 15.2 0.6 0.05 14.1 0.4 1.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 Ax_dynein_light PF10211.9 KXG45137.1 - 0.033 14.1 4.4 0.045 13.7 4.4 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain MRPL52 PF18699.1 KXG45137.1 - 0.041 14.1 4.0 0.22 11.7 0.1 2.1 1 1 1 2 2 2 0 Mitoribosomal protein mL52 CENP-Q PF13094.6 KXG45137.1 - 0.081 13.1 5.7 1.4 9.1 2.5 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit LIN52 PF10044.9 KXG45137.1 - 0.11 13.2 1.1 0.19 12.5 1.1 1.4 1 1 0 1 1 1 0 Retinal tissue protein ADIP PF11559.8 KXG45137.1 - 0.21 11.7 7.1 0.32 11.1 7.1 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding HAUS-augmin3 PF14932.6 KXG45137.1 - 0.27 10.8 5.9 0.67 9.5 4.1 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SWI-SNF_Ssr4 PF08549.10 KXG45137.1 - 0.32 9.6 3.2 0.92 8.1 1.0 1.9 1 1 1 2 2 2 0 Fungal domain of unknown function (DUF1750) ADIP PF11559.8 KXG45138.1 - 0.0028 17.8 0.5 0.0045 17.1 0.5 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 KXG45138.1 - 0.0044 17.3 1.1 0.007 16.6 1.1 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Jnk-SapK_ap_N PF09744.9 KXG45138.1 - 0.0065 16.7 1.7 0.0092 16.2 1.7 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 DMPK_coil PF08826.10 KXG45138.1 - 0.0068 16.5 2.5 0.097 12.8 0.1 2.8 1 1 2 3 3 3 1 DMPK coiled coil domain like DivIC PF04977.15 KXG45138.1 - 0.0099 15.6 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Septum formation initiator Rootletin PF15035.6 KXG45138.1 - 0.01 15.9 2.0 0.014 15.5 2.0 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Lebercilin PF15619.6 KXG45138.1 - 0.014 15.0 0.5 0.026 14.2 0.5 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease GIT_CC PF16559.5 KXG45138.1 - 0.02 14.8 1.0 0.064 13.1 0.9 2.0 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor AAA_13 PF13166.6 KXG45138.1 - 0.033 12.9 0.3 0.041 12.5 0.3 1.1 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 KXG45138.1 - 0.044 12.7 1.6 0.062 12.2 1.1 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4763 PF15960.5 KXG45138.1 - 0.045 13.0 1.2 0.07 12.4 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) YabA PF06156.13 KXG45138.1 - 0.048 14.3 0.4 0.082 13.5 0.4 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Filament PF00038.21 KXG45138.1 - 0.05 13.2 0.7 0.075 12.6 0.3 1.5 2 0 0 2 2 2 0 Intermediate filament protein Myosin_tail_1 PF01576.19 KXG45138.1 - 0.061 11.1 1.2 0.077 10.8 1.2 1.1 1 0 0 1 1 1 0 Myosin tail Matrilin_ccoil PF10393.9 KXG45138.1 - 0.12 12.2 1.6 0.38 10.6 0.5 2.2 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF2205 PF10224.9 KXG45138.1 - 0.21 11.6 2.4 4.5 7.4 0.4 2.4 1 1 1 2 2 2 0 Short coiled-coil protein DUF1664 PF07889.12 KXG45138.1 - 0.23 11.5 0.7 0.37 10.8 0.3 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) Cep57_MT_bd PF06657.13 KXG45138.1 - 0.28 11.7 2.1 0.97 9.9 0.9 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 RVT_1 PF00078.27 KXG45139.1 - 1.6e-24 86.7 0.0 2.2e-15 56.8 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KXG45139.1 - 1.8e-23 82.6 0.1 8.1e-23 80.5 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.23 KXG45139.1 - 0.0002 21.3 14.8 0.00035 20.5 3.4 2.5 2 0 0 2 2 2 2 Zinc knuckle POX PF07526.11 KXG45139.1 - 0.097 13.2 0.6 0.24 12.0 0.6 1.6 1 0 0 1 1 1 0 Associated with HOX Cwf_Cwc_15 PF04889.12 KXG45139.1 - 0.51 10.0 15.7 0.031 14.0 9.8 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-CCHC_4 PF14392.6 KXG45139.1 - 3.6 7.4 6.6 3.8 7.3 0.5 2.5 2 0 0 2 2 2 0 Zinc knuckle OTT_1508_deam PF14441.6 KXG45140.1 - 7e-18 64.4 0.6 1.8e-17 63.1 0.6 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF3470 PF11953.8 KXG45140.1 - 0.28 11.2 0.9 29 4.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3470) Patatin PF01734.22 KXG45141.1 - 2.2e-06 28.0 0.2 6.3e-06 26.5 0.1 1.8 1 1 1 2 2 2 1 Patatin-like phospholipase RVT_1 PF00078.27 KXG45142.1 - 7.9e-32 110.6 0.0 1.5e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KXG45142.1 - 6.6e-25 87.3 0.2 1.6e-24 86.0 0.2 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 KXG45142.1 - 2.4e-09 37.5 0.2 5.6e-09 36.3 0.2 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.23 KXG45142.1 - 0.0032 17.0 0.0 0.023 14.2 0.0 2.3 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 KXG45142.1 - 0.077 13.1 0.9 0.2 11.8 0.9 1.8 1 0 0 1 1 1 0 Zinc knuckle RNase_H PF00075.24 KXG45143.1 - 7.4e-12 45.7 0.7 2.2e-11 44.1 0.7 1.9 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.27 KXG45143.1 - 8.9e-11 41.7 0.0 2.6e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fez1 PF06818.15 KXG45143.1 - 0.013 15.9 5.0 0.11 12.9 5.0 2.2 1 1 0 1 1 1 0 Fez1 Cluap1 PF10234.9 KXG45143.1 - 0.014 14.8 0.7 0.027 13.9 0.7 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF1664 PF07889.12 KXG45143.1 - 0.019 15.0 2.7 0.045 13.8 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 KXG45143.1 - 0.039 13.1 0.7 0.093 11.8 0.7 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 KXG45143.1 - 0.043 13.6 2.6 0.15 11.9 2.6 2.0 1 0 0 1 1 1 0 Septum formation initiator 2_5_RNA_ligase2 PF13563.6 KXG45143.1 - 0.051 13.5 0.1 3.7 7.5 0.0 3.0 3 0 0 3 3 3 0 2'-5' RNA ligase superfamily DUF3584 PF12128.8 KXG45143.1 - 0.061 10.8 0.3 0.1 10.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RasGAP_C PF03836.15 KXG45143.1 - 0.07 13.3 0.2 0.18 11.9 0.2 1.7 1 0 0 1 1 1 0 RasGAP C-terminus HALZ PF02183.18 KXG45143.1 - 0.15 12.3 1.2 0.35 11.1 1.2 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper EzrA PF06160.12 KXG45143.1 - 0.15 10.2 2.0 0.24 9.5 2.0 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA zf-RVT PF13966.6 KXG45143.1 - 0.16 12.7 3.2 0.46 11.2 0.1 2.8 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase INTS2 PF14750.6 KXG45143.1 - 0.17 9.4 0.0 0.27 8.8 0.0 1.2 1 0 0 1 1 1 0 Integrator complex subunit 2 YabA PF06156.13 KXG45143.1 - 0.18 12.4 0.5 0.76 10.5 0.2 2.2 2 0 0 2 2 1 0 Initiation control protein YabA RVT_3 PF13456.6 KXG45143.1 - 0.31 10.8 6.0 0.29 10.9 2.8 2.6 2 1 0 2 2 2 0 Reverse transcriptase-like AAA_13 PF13166.6 KXG45143.1 - 0.79 8.3 2.9 1.2 7.7 2.9 1.1 1 0 0 1 1 1 0 AAA domain HlyIII PF03006.20 KXG45144.1 - 1.4e-07 31.5 12.1 1.9e-07 31.0 12.1 1.2 1 0 0 1 1 1 1 Haemolysin-III related COX2_TM PF02790.15 KXG45144.1 - 0.0084 16.2 1.3 0.028 14.6 0.4 2.1 2 0 0 2 2 2 1 Cytochrome C oxidase subunit II, transmembrane domain NYN PF01936.18 KXG45147.1 - 1.8e-31 109.6 0.0 2.7e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 KXG45147.1 - 3.6e-16 58.7 0.0 8.1e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Fe-S_assembly PF04384.13 KXG45147.1 - 0.091 13.4 0.0 0.18 12.5 0.0 1.4 1 0 0 1 1 1 0 Iron-sulphur cluster assembly Ank_2 PF12796.7 KXG45148.1 - 4.2e-40 136.2 12.8 3.9e-12 46.6 0.1 5.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG45148.1 - 4e-28 97.4 1.3 2.8e-06 27.7 0.0 7.2 3 1 5 8 8 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KXG45148.1 - 2.7e-21 75.0 7.9 0.029 14.8 0.0 8.1 7 1 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 KXG45148.1 - 2e-20 70.7 1.0 0.21 12.3 0.0 9.6 10 0 0 10 10 9 4 Ankyrin repeat Ank_5 PF13857.6 KXG45148.1 - 1.1e-11 44.7 3.4 0.016 15.5 0.0 5.5 3 2 3 6 6 5 3 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KXG45148.1 - 3.5e-10 39.6 0.2 3.5e-10 39.6 0.2 2.5 3 0 0 3 3 3 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 KXG45148.1 - 1.3e-07 31.7 0.0 3.8e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXG45148.1 - 0.017 15.5 3.6 0.036 14.4 0.0 3.1 4 0 0 4 4 4 0 AAA ATPase domain Phage_HK97_TLTM PF06120.11 KXG45148.1 - 0.03 13.5 5.8 0.085 12.0 0.5 2.9 3 0 0 3 3 3 0 Tail length tape measure protein DUF677 PF05055.12 KXG45148.1 - 0.038 12.9 0.2 0.084 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF677) AAA_14 PF13173.6 KXG45148.1 - 0.04 14.0 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain ERAP1_C PF11838.8 KXG45148.1 - 0.1 12.1 1.6 8.7 5.8 0.1 3.0 3 0 0 3 3 3 0 ERAP1-like C-terminal domain AAA_22 PF13401.6 KXG45148.1 - 0.29 11.4 1.6 3.9 7.8 0.0 3.2 4 0 0 4 4 4 0 AAA domain FLgD_tudor PF13861.6 KXG45148.1 - 0.29 11.4 2.4 4.2 7.7 0.3 3.6 2 1 0 2 2 2 0 FlgD Tudor-like domain Rx_N PF18052.1 KXG45148.1 - 0.46 10.8 8.0 0.37 11.1 2.9 2.8 1 1 1 2 2 2 0 Rx N-terminal domain SesA PF17107.5 KXG45148.1 - 0.64 10.2 4.2 0.23 11.6 1.1 2.0 2 0 0 2 2 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases STAT_int PF02865.17 KXG45148.1 - 1.1 9.7 4.3 0.71 10.3 0.3 2.9 3 0 0 3 3 3 0 STAT protein, protein interaction domain RICH PF05062.12 KXG45148.1 - 1.9 8.9 9.2 0.55 10.6 0.5 3.0 3 0 0 3 3 3 0 RICH domain Syntaxin_2 PF14523.6 KXG45148.1 - 2 8.8 5.4 0.38 11.2 0.2 2.5 3 0 0 3 3 2 0 Syntaxin-like protein PKcGMP_CC PF16808.5 KXG45148.1 - 4 7.4 6.6 0.43 10.5 1.3 2.2 2 0 0 2 2 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sugar_tr PF00083.24 KXG45150.1 - 1e-74 252.0 24.1 1.3e-74 251.7 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG45150.1 - 8.4e-14 51.2 37.5 1.5e-13 50.5 27.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily PK PF00224.21 KXG45152.1 - 9.8e-174 577.2 3.0 1.2e-173 576.9 3.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KXG45152.1 - 2.8e-39 134.0 0.0 9.2e-39 132.3 0.0 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KXG45152.1 - 0.00014 21.0 0.5 0.00035 19.8 0.3 1.7 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KXG45152.1 - 0.035 13.1 0.1 0.3 10.1 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain YchF-GTPase_C PF06071.13 KXG45153.1 - 7.4e-37 125.4 0.0 1.7e-36 124.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KXG45153.1 - 3.5e-21 75.4 0.0 9e-21 74.1 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXG45153.1 - 5.2e-07 29.3 0.0 9.4e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Methyltransf_2 PF00891.18 KXG45154.1 - 9.5e-27 93.7 0.1 2.5e-26 92.3 0.1 1.7 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KXG45154.1 - 1.2e-05 25.2 0.0 8.5e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Dimerisation domain HTH_24 PF13412.6 KXG45154.1 - 0.066 12.8 0.1 0.28 10.8 0.0 2.1 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 KXG45154.1 - 0.13 12.7 0.0 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator Dimerisation PF08100.11 KXG45154.1 - 0.13 12.3 0.1 0.56 10.3 0.1 2.1 2 0 0 2 2 2 0 Dimerisation domain PIP5K PF01504.18 KXG45156.1 - 6e-33 114.2 0.0 5.2e-25 88.2 0.1 2.7 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KXG45156.1 - 1.2e-26 93.4 0.0 2.1e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KXG45156.1 - 1.8e-14 53.6 5.4 1.8e-14 53.6 5.4 1.9 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.22 KXG45156.1 - 8.8 6.3 14.1 0.029 14.3 4.0 2.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MscS_TM PF12794.7 KXG45157.1 - 4 6.2 4.0 6.3 5.5 4.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF4746 PF15928.5 KXG45157.1 - 4.5 6.6 8.2 13 5.1 8.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SUR7 PF06687.12 KXG45158.1 - 1e-48 165.8 12.3 1.4e-48 165.4 12.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family LapA_dom PF06305.11 KXG45158.1 - 0.53 10.1 0.0 0.53 10.1 0.0 2.7 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain DUF3742 PF12553.8 KXG45158.1 - 0.84 9.8 8.1 1.2 9.2 1.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3742) DUF4191 PF13829.6 KXG45158.1 - 1.6 8.0 3.6 2.6 7.3 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Cellulase PF00150.18 KXG45159.1 - 1.8e-53 181.8 2.0 2.1e-53 181.6 2.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Lipase_GDSL_2 PF13472.6 KXG45160.1 - 7.7e-05 23.2 0.2 0.00011 22.7 0.2 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXG45160.1 - 0.0084 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase WD40 PF00400.32 KXG45161.1 - 1.8e-15 57.1 32.2 5.7e-06 27.0 0.6 10.8 11 0 0 11 11 11 4 WD domain, G-beta repeat DUF281 PF03436.13 KXG45161.1 - 0.12 12.8 0.2 0.44 11.0 0.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF281) MctB PF11382.8 KXG45161.1 - 0.52 10.0 3.4 0.79 9.4 3.4 1.2 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB XPG_N PF00752.17 KXG45162.1 - 1.3e-34 118.7 0.0 4.9e-34 116.8 0.0 2.1 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KXG45162.1 - 3.1e-25 88.3 1.0 9.2e-25 86.8 0.0 2.3 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 KXG45162.1 - 5e-05 23.8 0.0 0.00019 22.0 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.20 KXG45162.1 - 0.002 17.9 0.3 0.002 17.9 0.3 3.9 3 0 0 3 3 3 2 Ubiquitin interaction motif HHH_5 PF14520.6 KXG45162.1 - 0.019 15.6 0.0 0.046 14.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Transposase_20 PF02371.16 KXG45162.1 - 0.035 14.4 0.0 0.082 13.2 0.0 1.6 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family Pil1 PF13805.6 KXG45163.1 - 9.8e-122 405.5 0.1 1.3e-121 405.2 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 bZIP_2 PF07716.15 KXG45164.1 - 8.5e-14 51.4 12.9 1.4e-13 50.7 12.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KXG45164.1 - 0.0001 22.4 10.0 0.00018 21.5 10.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF4094 PF13334.6 KXG45164.1 - 0.018 15.4 0.5 0.03 14.7 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) SIKE PF05769.11 KXG45164.1 - 0.024 14.6 2.2 0.033 14.1 2.2 1.1 1 0 0 1 1 1 0 SIKE family DUF3552 PF12072.8 KXG45164.1 - 0.068 12.6 8.0 0.097 12.1 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) TSC22 PF01166.18 KXG45164.1 - 0.15 12.4 1.0 0.29 11.5 1.0 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF1932 PF09130.11 KXG45165.1 - 1.2e-15 57.2 0.0 2.6e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 KXG45165.1 - 1.1e-06 28.9 0.1 1.2e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXG45165.1 - 2.4e-05 24.8 0.1 6.3e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXG45165.1 - 0.0017 17.8 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_transf_21 PF13506.6 KXG45165.1 - 0.1 12.1 0.0 0.26 10.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 21 Rossmann-like PF10727.9 KXG45165.1 - 0.83 9.5 4.2 0.44 10.4 0.6 2.3 3 0 0 3 3 3 0 Rossmann-like domain MFS_1 PF07690.16 KXG45166.1 - 1.8e-39 135.7 27.8 1.8e-39 135.7 27.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KXG45167.1 - 6.9e-15 54.8 0.1 1.2e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG45167.1 - 2.2e-06 27.7 11.1 3.7e-06 26.9 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MCM_OB PF17207.3 KXG45167.1 - 0.93 9.4 4.3 1.9 8.3 4.3 1.4 1 0 0 1 1 1 0 MCM OB domain Fungal_trans PF04082.18 KXG45168.1 - 1.1e-23 83.6 1.4 1.3e-23 83.3 0.6 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Spc7_N PF15402.6 KXG45169.1 - 0 1063.0 68.6 4.1e-202 674.0 37.9 3.1 1 1 2 3 3 3 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 KXG45169.1 - 6.8e-127 422.6 4.1 1.3e-126 421.6 4.1 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3016 PF11454.8 KXG45169.1 - 0.02 14.7 0.1 0.062 13.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) Sec8_exocyst PF04048.14 KXG45169.1 - 0.029 14.3 2.0 0.09 12.7 2.0 1.8 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain HMMR_N PF15905.5 KXG45169.1 - 0.18 11.3 14.5 0.54 9.7 14.5 1.8 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PCRF PF03462.18 KXG45169.1 - 0.7 9.7 6.8 2.9 7.7 6.8 2.1 1 0 0 1 1 1 0 PCRF domain V_ATPase_I PF01496.19 KXG45169.1 - 0.76 7.6 3.3 1.3 6.9 3.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 KXG45169.1 - 6.5 6.2 9.1 0.45 10.0 3.3 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit MAT1 PF06391.13 KXG45169.1 - 7 6.4 15.1 11 5.7 7.5 2.9 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 FapA PF03961.13 KXG45169.1 - 7.3 5.1 8.3 1.7 7.2 4.9 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A Ribosomal_S17_N PF16205.5 KXG45170.1 - 4.1e-34 116.8 0.6 7.8e-34 115.9 0.6 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KXG45170.1 - 8.8e-28 96.2 1.0 1.8e-27 95.2 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 ANTH PF07651.16 KXG45172.1 - 1.5e-58 198.0 0.0 1.9e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KXG45172.1 - 5.4e-07 29.7 0.0 2.6e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 ENTH domain Fungal_trans_2 PF11951.8 KXG45173.1 - 4.2e-12 45.6 0.0 2e-11 43.4 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain TFIIA PF03153.13 KXG45173.1 - 0.86 9.5 3.6 1.1 9.1 3.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gpr1_Fun34_YaaH PF01184.19 KXG45174.1 - 2.3e-86 288.7 19.5 2.8e-86 288.4 19.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Oxidored_FMN PF00724.20 KXG45175.1 - 1.5e-95 320.4 0.0 1.7e-95 320.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ribosomal_S13_N PF08069.12 KXG45175.1 - 0.15 12.1 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain DUF5572 PF17733.1 KXG45177.1 - 0.32 10.9 0.1 0.32 10.9 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5572) WD40 PF00400.32 KXG45178.1 - 3.9e-20 71.8 12.9 0.00019 22.2 0.1 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG45178.1 - 3.6e-17 62.5 0.0 7.8e-07 29.3 0.0 5.5 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXG45178.1 - 1.4e-05 25.1 0.4 0.017 15.0 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXG45178.1 - 0.0013 17.8 0.1 5.5 5.8 0.0 4.0 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein HIRA_B PF09453.10 KXG45178.1 - 0.0023 17.7 0.3 0.0023 17.7 0.3 2.5 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.12 KXG45178.1 - 0.11 12.5 7.2 8 6.5 0.2 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KXG45178.1 - 0.12 11.6 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain Glyco_transf_20 PF00982.21 KXG45179.1 - 4.7e-144 480.6 0.0 3.7e-143 477.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KXG45179.1 - 6.5e-25 87.6 0.0 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Rad4 PF03835.15 KXG45180.1 - 9.9e-15 54.5 3.5 1.8e-14 53.6 3.5 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KXG45180.1 - 3.5e-11 43.5 2.4 8.4e-11 42.3 2.4 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily SOG2 PF10428.9 KXG45180.1 - 0.52 9.5 6.5 0.77 8.9 6.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein CAP_N PF01213.19 KXG45180.1 - 3.8 6.9 8.0 6.8 6.1 8.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Glyco_hydro_71 PF03659.14 KXG45181.1 - 8.4e-123 409.9 0.8 1e-122 409.6 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.6 KXG45181.1 - 0.041 13.9 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Memo PF01875.17 KXG45182.1 - 5.4e-66 222.5 0.0 6.4e-66 222.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein LSM PF01423.22 KXG45184.1 - 1.8e-07 30.8 0.0 2.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXG45184.1 - 0.0023 18.0 0.0 0.0041 17.2 0.0 1.6 1 1 0 1 1 1 1 Ataxin 2 SM domain DUF2380 PF09533.10 KXG45184.1 - 0.015 14.9 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) Metallophos PF00149.28 KXG45185.1 - 6.5e-37 128.0 0.1 1e-36 127.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXG45185.1 - 4.4e-18 65.4 0.0 8.1e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain AOX PF01786.17 KXG45186.1 - 6e-90 300.6 0.1 6.9e-90 300.3 0.1 1.0 1 0 0 1 1 1 1 Alternative oxidase DUF2781 PF10914.8 KXG45186.1 - 0.019 15.3 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) Aldedh PF00171.22 KXG45187.1 - 6.3e-96 321.7 0.0 7.4e-96 321.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PsbW PF07123.12 KXG45188.1 - 0.031 14.3 2.2 0.12 12.3 1.3 2.3 1 1 1 2 2 2 0 Photosystem II reaction centre W protein (PsbW) Sugar_tr PF00083.24 KXG45189.1 - 8.6e-98 328.1 16.9 9.9e-98 327.9 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG45189.1 - 6.4e-24 84.5 38.3 4e-16 58.9 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro_dh PF01619.18 KXG45190.1 - 8.2e-64 216.0 0.1 9e-64 215.8 0.1 1.1 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.24 KXG45190.1 - 0.048 13.1 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DAO PF01266.24 KXG45192.1 - 1.2e-29 104.0 0.0 1.5e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG45192.1 - 2.6e-05 24.4 0.0 5.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXG45192.1 - 0.002 17.5 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG45192.1 - 0.023 15.3 0.0 0.075 13.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG45192.1 - 0.031 13.3 0.0 0.34 10.0 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 KXG45192.1 - 0.086 12.1 0.0 0.23 10.7 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain Fungal_trans PF04082.18 KXG45193.1 - 2.2e-08 33.5 0.3 9.8e-08 31.3 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain RabGAP-TBC PF00566.18 KXG45195.1 - 9.9e-33 113.6 0.6 1.6e-32 112.9 0.6 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 KXG45196.1 - 5.8e-56 189.8 0.0 8.9e-56 189.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG45196.1 - 2.1e-20 73.1 0.0 3.1e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG45196.1 - 8.6e-05 22.0 0.0 0.00023 20.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXG45196.1 - 0.00025 21.0 0.1 0.0068 16.4 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KXG45196.1 - 0.0004 19.8 0.0 0.00092 18.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXG45196.1 - 0.0026 16.7 0.0 0.0048 15.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KXG45196.1 - 0.012 15.2 0.0 0.033 13.8 0.0 1.7 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KXG45196.1 - 0.018 13.9 0.0 0.034 12.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Pex14_N PF04695.13 KXG45196.1 - 3.1 8.5 8.5 0.64 10.7 4.3 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region F-box-like PF12937.7 KXG45197.1 - 5.5e-12 45.4 0.5 3.5e-11 42.8 0.0 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KXG45197.1 - 3.9e-10 39.3 0.0 4.7e-09 35.9 0.0 3.0 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 KXG45197.1 - 7.1e-10 38.1 8.0 0.033 14.2 0.0 7.1 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.7 KXG45197.1 - 1.5e-05 25.2 10.8 0.041 14.3 0.0 4.7 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) Nucleo_P87 PF07267.11 KXG45197.1 - 0.008 15.1 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 LRR_1 PF00560.33 KXG45197.1 - 0.018 15.5 15.2 3.9 8.4 0.1 6.4 7 0 0 7 7 7 0 Leucine Rich Repeat PRANC PF09372.10 KXG45197.1 - 0.19 12.1 0.0 0.6 10.5 0.0 1.9 1 0 0 1 1 1 0 PRANC domain B12D PF06522.11 KXG45198.1 - 0.016 15.0 0.0 0.046 13.5 0.0 1.8 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit CCDC84 PF14968.6 KXG45198.1 - 0.4 10.3 2.5 0.58 9.7 2.5 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 Efg1 PF10153.9 KXG45199.1 - 1.4e-32 112.4 8.6 1.4e-32 112.4 8.6 2.9 3 0 0 3 3 3 1 rRNA-processing protein Efg1 PTS_2-RNA PF01885.16 KXG45200.1 - 3.2e-63 213.0 0.0 5.3e-63 212.3 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family zinc_ribbon_16 PF17034.5 KXG45200.1 - 1.3e-06 28.7 0.5 3.1e-06 27.4 0.5 1.7 1 0 0 1 1 1 1 Zinc-ribbon like family Dioxygenase_C PF00775.21 KXG45201.1 - 1.5e-48 164.7 0.0 2e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXG45201.1 - 2.8e-26 91.1 0.1 4.3e-26 90.6 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KXG45201.1 - 6.8e-06 26.3 0.0 2.5e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KXG45201.1 - 0.015 15.3 0.0 0.66 10.0 0.0 2.8 3 0 0 3 3 3 0 CarboxypepD_reg-like domain Lipase_C PF18067.1 KXG45201.1 - 0.022 15.3 0.0 0.046 14.3 0.0 1.5 1 0 0 1 1 1 0 Lipase C-terminal domain Abhydrolase_1 PF00561.20 KXG45202.1 - 1.7e-20 73.8 0.0 1e-16 61.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG45202.1 - 5.4e-19 68.4 0.1 2.1e-18 66.5 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXG45202.1 - 5.5e-15 56.6 0.0 7.4e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KXG45202.1 - 1.8e-06 26.9 0.0 2.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.21 KXG45202.1 - 0.00058 19.4 0.0 0.026 14.0 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KXG45202.1 - 0.0012 18.7 0.1 1.4 8.7 0.0 2.8 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase BAAT_C PF08840.11 KXG45202.1 - 0.0013 18.7 0.1 0.0036 17.3 0.1 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 KXG45202.1 - 0.0042 16.7 0.0 0.83 9.2 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Ser_hydrolase PF06821.13 KXG45202.1 - 0.0052 16.7 0.1 0.049 13.5 0.1 2.1 1 1 0 1 1 1 1 Serine hydrolase DUF915 PF06028.11 KXG45202.1 - 0.009 15.4 0.0 0.13 11.6 0.0 2.4 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.7 KXG45202.1 - 0.024 14.4 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.20 KXG45202.1 - 0.032 13.9 0.2 0.058 13.0 0.1 1.5 1 1 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 KXG45202.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain U79_P34 PF03064.16 KXG45203.1 - 0.046 13.1 4.7 0.072 12.4 4.7 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NARP1 PF12569.8 KXG45203.1 - 1.8 7.3 8.7 3 6.7 8.7 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Aldo_ket_red PF00248.21 KXG45204.1 - 5.9e-36 124.2 0.1 3e-25 89.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family eRF1_1 PF03463.15 KXG45205.1 - 3.3e-46 156.5 0.0 5.1e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 KXG45205.1 - 8.8e-20 71.3 0.0 1.8e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 KXG45205.1 - 1.8e-19 70.4 0.0 2.8e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 JHD PF17811.1 KXG45206.1 - 0.027 15.0 0.3 0.2 12.2 0.2 2.1 2 0 0 2 2 2 0 Jumonji helical domain MFS_1 PF07690.16 KXG45207.1 - 3.2e-19 69.1 40.0 7e-14 51.5 23.5 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Peptidase_C14 PF00656.22 KXG45208.1 - 2.5e-63 214.3 0.0 3.1e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Cpn60_TCP1 PF00118.24 KXG45209.1 - 4.6e-151 503.8 4.5 5.3e-151 503.6 4.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FtsA PF14450.6 KXG45209.1 - 0.055 13.9 1.1 0.17 12.3 0.8 1.8 1 1 0 1 1 1 0 Cell division protein FtsA Rep_fac_C PF08542.11 KXG45209.1 - 0.066 13.6 0.0 7.4 7.1 0.0 2.8 2 0 0 2 2 2 0 Replication factor C C-terminal domain Beta_helix_2 PF18835.1 KXG45209.1 - 0.16 11.7 0.2 3.5 7.4 0.3 2.6 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase zf-H2C2 PF09337.10 KXG45210.1 - 1.5e-15 57.1 1.8 2.6e-15 56.3 1.8 1.4 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KXG45210.1 - 2.1e-10 40.6 0.5 3.9e-10 39.7 0.5 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KXG45210.1 - 5.8e-06 26.5 0.0 1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KXG45210.1 - 0.0082 16.8 0.0 0.036 14.7 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG45210.1 - 0.09 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 KXG45210.1 - 0.19 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LRR_4 PF12799.7 KXG45211.1 - 0.00015 22.1 0.4 12 6.5 0.0 4.3 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXG45211.1 - 0.0067 16.4 0.7 12 6.3 0.0 3.9 4 0 0 4 4 4 2 Leucine Rich repeat Ribosomal_S26e PF01283.19 KXG45212.1 - 7.6e-53 177.5 7.6 9e-53 177.3 7.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KXG45212.1 - 0.026 14.5 0.5 0.065 13.2 0.0 1.9 2 0 0 2 2 2 0 Zinc binding domain CBS PF00571.28 KXG45213.1 - 2.9e-35 120.5 5.0 4.5e-09 36.6 0.0 5.3 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 KXG45213.1 - 1.9e-10 40.5 0.0 6e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 PB1 domain Importin_rep_4 PF18808.1 KXG45214.1 - 1.8e-33 114.7 6.0 6.9e-33 112.8 1.6 3.6 3 0 0 3 3 3 1 Importin repeat HEAT_EZ PF13513.6 KXG45214.1 - 3e-22 78.7 14.2 1.1e-10 41.8 0.4 9.6 7 2 2 9 9 9 3 HEAT-like repeat Importin_rep_5 PF18816.1 KXG45214.1 - 9e-22 77.1 1.6 9e-22 77.1 1.6 2.2 2 0 0 2 2 1 1 Importin repeat HEAT_2 PF13646.6 KXG45214.1 - 5.1e-17 62.0 5.2 0.00018 21.8 0.0 7.7 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.22 KXG45214.1 - 2e-14 52.5 18.1 0.016 15.4 0.0 12.5 15 0 0 15 15 13 2 HEAT repeat Importin_rep_6 PF18829.1 KXG45214.1 - 9e-14 51.5 0.7 9e-14 51.5 0.7 3.0 3 0 0 3 3 3 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 KXG45214.1 - 1.8e-09 38.1 0.3 0.0014 19.2 0.0 6.2 3 2 4 7 7 6 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KXG45214.1 - 2e-08 33.8 9.7 1.8e-06 27.3 0.8 5.5 5 1 1 6 6 6 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 KXG45214.1 - 4.3e-08 33.2 2.5 0.24 11.3 0.0 6.7 6 3 2 9 9 8 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KXG45214.1 - 9.7e-08 32.2 0.0 0.48 10.5 0.0 5.1 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 KXG45214.1 - 2.7e-07 30.5 0.2 0.0076 16.0 0.1 4.6 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 KXG45214.1 - 3.8e-07 29.9 1.3 0.13 11.8 0.1 6.1 5 2 3 8 8 8 2 CLASP N terminal Adaptin_N PF01602.20 KXG45214.1 - 7.6e-07 28.1 0.0 0.0031 16.2 0.1 3.2 2 1 0 3 3 3 2 Adaptin N terminal region IFRD PF05004.13 KXG45214.1 - 5.9e-06 25.6 1.0 0.024 13.8 0.1 4.2 3 2 1 4 4 4 2 Interferon-related developmental regulator (IFRD) Arm PF00514.23 KXG45214.1 - 8e-05 22.5 4.8 0.16 12.1 0.1 4.5 5 0 0 5 5 3 2 Armadillo/beta-catenin-like repeat MMS19_N PF14500.6 KXG45214.1 - 0.00033 20.3 0.4 3 7.3 0.1 4.6 5 1 0 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II IBN_N PF03810.19 KXG45214.1 - 0.016 15.2 0.0 0.21 11.5 0.0 2.9 2 0 0 2 2 2 0 Importin-beta N-terminal domain RTP1_C1 PF10363.9 KXG45214.1 - 0.055 13.6 0.4 22 5.3 0.1 5.0 6 1 1 7 7 5 0 Required for nuclear transport of RNA pol II C-terminus 1 DNA_alkylation PF08713.11 KXG45214.1 - 0.078 12.7 0.0 0.32 10.7 0.0 2.2 1 0 0 1 1 1 0 DNA alkylation repair enzyme Rif1_N PF12231.8 KXG45214.1 - 0.23 10.4 1.3 6 5.8 0.0 3.4 4 0 0 4 4 4 0 Rap1-interacting factor 1 N terminal GP24_25 PF17388.2 KXG45214.1 - 0.5 10.3 3.2 0.6 10.1 0.4 2.7 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 Telomere_reg-2 PF10193.9 KXG45214.1 - 3.4 8.2 7.3 2 8.9 0.4 3.9 3 2 1 4 4 3 0 Telomere length regulation protein Fe-ADH PF00465.19 KXG45215.1 - 1.2e-65 221.8 0.1 2.2e-65 220.8 0.1 1.4 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase NmrA PF05368.13 KXG45215.1 - 3.7e-15 56.1 0.0 3.6e-09 36.5 0.0 2.3 1 1 1 2 2 2 2 NmrA-like family Fe-ADH_2 PF13685.6 KXG45215.1 - 1.1e-11 44.9 1.0 2.2e-05 24.3 0.1 2.7 3 0 0 3 3 3 2 Iron-containing alcohol dehydrogenase Chalcone_2 PF16035.5 KXG45216.1 - 6.4e-83 277.5 0.0 9.5e-83 277.0 0.0 1.3 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 KXG45216.1 - 0.00032 20.9 0.0 0.0025 17.9 0.0 2.2 2 0 0 2 2 2 1 Chalcone isomerase-like Glutaredoxin PF00462.24 KXG45217.1 - 1.6e-19 69.9 0.0 2.5e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 KXG45217.1 - 0.00027 21.3 0.1 0.00034 20.9 0.1 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 KXG45217.1 - 0.0016 18.9 0.0 0.0019 18.6 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 KXG45217.1 - 0.0087 16.0 0.0 0.01 15.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KXG45217.1 - 0.02 14.7 0.1 0.13 12.0 0.1 1.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 KXG45217.1 - 0.02 14.9 0.0 0.03 14.4 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin domain TraF PF13728.6 KXG45217.1 - 0.047 13.5 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein BAG PF02179.16 KXG45219.1 - 8.2e-16 58.2 0.0 1.3e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KXG45219.1 - 0.00013 21.6 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family TPR_10 PF13374.6 KXG45220.1 - 3.6e-56 185.6 29.7 1.5e-08 34.2 0.1 10.1 9 1 1 10 10 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 KXG45220.1 - 3e-50 168.4 25.9 1.6e-12 47.5 1.3 6.8 2 1 2 6 6 6 6 Tetratricopeptide repeat TPR_19 PF14559.6 KXG45220.1 - 1.2e-20 73.8 23.9 0.0016 18.9 0.9 8.7 2 2 7 9 9 9 8 Tetratricopeptide repeat Patatin PF01734.22 KXG45220.1 - 3.6e-19 69.7 0.0 7.2e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_7 PF13176.6 KXG45220.1 - 4.6e-18 63.9 17.0 0.88 9.7 0.0 9.9 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 KXG45220.1 - 1.2e-17 62.6 14.8 0.7 10.2 0.0 10.3 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXG45220.1 - 2.1e-13 49.9 25.7 1.5 9.9 0.2 10.3 9 1 1 10 10 9 3 Tetratricopeptide repeat TPR_20 PF14561.6 KXG45220.1 - 3e-11 43.5 26.1 0.18 12.1 0.1 9.0 2 1 7 9 9 9 6 Tetratricopeptide repeat TPR_6 PF13174.6 KXG45220.1 - 8e-11 41.9 15.3 2.6 8.9 0.0 10.4 10 1 1 11 11 10 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG45220.1 - 1.9e-09 37.6 9.8 0.76 10.1 0.0 6.2 2 1 4 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KXG45220.1 - 6.8e-09 35.2 4.8 12 6.0 0.0 8.7 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXG45220.1 - 3e-08 33.3 7.0 6.8 7.2 0.0 9.1 8 1 1 9 9 9 1 Tetratricopeptide repeat NB-ARC PF00931.22 KXG45220.1 - 1.6e-07 30.7 0.0 3.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KXG45220.1 - 2.2e-06 28.0 0.0 6.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain PPR PF01535.20 KXG45220.1 - 2.6e-05 24.2 0.9 1e+02 3.5 0.0 8.0 8 1 1 9 9 9 0 PPR repeat TPR_4 PF07721.14 KXG45220.1 - 4.4e-05 23.7 22.2 35 5.4 0.0 9.0 8 1 1 9 9 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXG45220.1 - 0.00032 20.8 15.2 1.6 8.9 0.1 7.0 3 3 2 6 6 6 2 Tetratricopeptide repeat PPR_1 PF12854.7 KXG45220.1 - 0.0048 16.6 8.6 1.1e+02 2.6 0.0 7.5 8 0 0 8 8 8 0 PPR repeat TPR_17 PF13431.6 KXG45220.1 - 0.014 15.7 5.4 1.5e+02 3.1 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXG45220.1 - 0.024 15.3 22.8 2.7 8.7 1.1 7.4 4 3 3 8 8 7 0 Tetratricopeptide repeat AIF-MLS PF14962.6 KXG45220.1 - 0.053 13.5 10.2 14 5.6 0.1 4.7 2 1 2 5 5 5 0 Mitochondria Localisation Sequence CODH_A_N PF18537.1 KXG45220.1 - 0.51 10.4 3.2 20 5.3 0.0 3.9 2 1 1 4 4 4 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain LMBR1 PF04791.16 KXG45221.1 - 2.6e-131 439.1 1.0 3e-131 438.8 1.0 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein FUSC PF04632.12 KXG45221.1 - 0.068 11.7 8.9 0.023 13.3 1.9 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Apolipoprotein PF01442.18 KXG45221.1 - 1 9.2 3.2 1 9.2 0.3 1.9 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Med15_fungi PF05397.12 KXG45222.1 - 6.1e-34 116.7 0.2 6.1e-34 116.7 0.2 4.8 5 0 0 5 5 5 1 Mediator complex subunit 15 EamA PF00892.20 KXG45222.1 - 2.1e-12 47.4 21.4 4.3e-06 26.9 2.2 2.4 2 0 0 2 2 2 2 EamA-like transporter family KIX_2 PF16987.5 KXG45222.1 - 7.5e-09 35.5 0.8 5.6e-08 32.7 0.8 2.7 1 0 0 1 1 1 1 KIX domain Nuc_sug_transp PF04142.15 KXG45222.1 - 1.2e-08 34.5 0.7 2.3e-08 33.6 0.7 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KXG45222.1 - 1.7e-05 24.2 7.1 3.8e-05 23.1 7.1 1.5 1 1 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 KXG45222.1 - 0.0002 20.4 3.0 0.0002 20.4 3.0 2.1 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 KXG45222.1 - 0.0069 15.8 0.2 0.0069 15.8 0.2 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family CPP1-like PF11833.8 KXG45222.1 - 0.074 12.7 0.0 0.074 12.7 0.0 2.8 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like SMYLE_N PF18615.1 KXG45222.1 - 1.1 8.8 7.6 1.8 8.1 2.4 2.8 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Adaptin_N PF01602.20 KXG45223.1 - 4.6e-141 470.9 1.0 5.4e-141 470.7 1.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KXG45223.1 - 2.8e-18 66.2 0.0 5.2e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KXG45223.1 - 5.9e-08 32.9 6.8 0.00037 20.6 0.1 4.3 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXG45223.1 - 4.9e-07 30.1 1.1 0.065 13.6 0.0 4.1 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KXG45223.1 - 0.0017 18.4 0.9 6.7 7.3 0.1 4.4 3 0 0 3 3 3 1 HEAT repeat DUF3730 PF12530.8 KXG45223.1 - 0.0053 16.3 0.0 0.45 10.0 0.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3730) Arm PF00514.23 KXG45223.1 - 0.072 13.2 0.8 1.3e+02 2.8 0.1 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat RICTOR_M PF14666.6 KXG45223.1 - 0.074 12.8 0.5 0.38 10.5 0.0 2.4 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain MBOAT PF03062.19 KXG45224.1 - 3.1e-39 135.3 12.9 3.1e-39 135.3 12.9 2.0 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family DnaJ PF00226.31 KXG45225.1 - 4.6e-19 68.3 0.6 1.5e-18 66.7 0.6 1.9 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.28 KXG45226.1 - 9.9e-12 45.8 0.4 1.8e-11 44.9 0.4 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXG45226.1 - 6.6e-05 23.2 0.4 0.00077 19.7 0.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L13 PF00572.18 KXG45227.1 - 2.8e-10 40.5 0.3 2.9e-06 27.5 0.0 2.8 2 1 0 2 2 2 2 Ribosomal protein L13 DSBA PF01323.20 KXG45227.1 - 0.031 14.0 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain AMP-binding PF00501.28 KXG45228.1 - 1.4e-67 228.2 0.0 1.7e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG45228.1 - 3.5e-18 66.3 0.0 8.9e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LRR_6 PF13516.6 KXG45229.1 - 2.2e-14 52.2 21.6 1.3 9.3 0.0 11.8 12 0 0 12 12 12 5 Leucine Rich repeat F-box-like PF12937.7 KXG45229.1 - 1.3e-12 47.4 0.5 5e-12 45.5 0.1 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KXG45229.1 - 1.5e-08 34.8 13.2 1.5 9.3 0.2 7.8 3 2 2 8 8 8 4 Leucine Rich repeats (2 copies) F-box PF00646.33 KXG45229.1 - 5e-05 23.1 0.0 0.00026 20.8 0.0 2.3 1 0 0 1 1 1 1 F-box domain DUF1699 PF08004.11 KXG45229.1 - 0.00043 20.0 1.1 0.048 13.3 0.0 3.5 3 2 2 5 5 5 1 Protein of unknown function (DUF1699) Recep_L_domain PF01030.24 KXG45229.1 - 0.088 12.9 0.1 32 4.7 0.0 3.5 2 2 1 4 4 4 0 Receptor L domain Peptidase_M28 PF04389.17 KXG45230.1 - 4.6e-33 114.6 0.0 7.1e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 ATP-synt_8 PF00895.20 KXG45230.1 - 0.0083 16.6 0.4 0.0083 16.6 0.4 4.1 6 0 0 6 6 6 1 ATP synthase protein 8 Peptidase_M20 PF01546.28 KXG45230.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Epimerase PF01370.21 KXG45232.1 - 9.9e-25 87.4 0.5 5.5e-24 85.0 0.5 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG45232.1 - 1.8e-15 57.2 0.0 4.3e-15 56.0 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXG45232.1 - 5.3e-10 38.8 0.1 1.4e-09 37.4 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXG45232.1 - 3.8e-09 36.1 0.0 3.4e-07 29.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KXG45232.1 - 6.2e-08 32.7 0.0 1.3e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KXG45232.1 - 1.8e-07 30.6 0.0 2.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXG45232.1 - 0.00033 19.9 0.0 0.0014 17.8 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KXG45232.1 - 0.018 14.6 0.2 0.24 10.9 0.1 2.1 2 0 0 2 2 2 0 NmrA-like family Urease_beta PF00699.20 KXG45232.1 - 0.07 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Urease beta subunit KR PF08659.10 KXG45232.1 - 0.098 12.6 0.3 0.7 9.8 0.3 2.2 1 1 0 1 1 1 0 KR domain Lipase_GDSL_2 PF13472.6 KXG45233.1 - 2.2e-20 73.8 0.0 2.8e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.6 KXG45233.1 - 8.6e-05 22.7 0.0 0.018 15.2 0.0 2.6 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXG45233.1 - 0.0004 20.4 0.0 0.00049 20.1 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pro_racemase PF05544.11 KXG45234.1 - 8.2e-128 426.0 0.1 9.2e-128 425.9 0.1 1.0 1 0 0 1 1 1 1 Proline racemase AA_permease_2 PF13520.6 KXG45235.1 - 1.4e-47 162.5 53.4 1.4e-47 162.5 53.4 1.9 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 KXG45235.1 - 9.5e-28 97.0 48.2 9.5e-28 97.0 48.2 2.1 2 0 0 2 2 2 1 Amino acid permease CorA PF01544.18 KXG45235.1 - 1.3e-05 24.7 1.3 4.5e-05 22.9 1.3 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Fungal_trans_2 PF11951.8 KXG45236.1 - 4e-26 91.7 6.2 6.2e-26 91.1 6.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Carbpep_Y_N PF05388.11 KXG45236.1 - 0.092 13.3 1.3 10 6.7 0.0 3.0 3 0 0 3 3 3 0 Carboxypeptidase Y pro-peptide FAA_hydrolase PF01557.18 KXG45237.1 - 3.1e-62 210.1 0.0 3.7e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.16 KXG45238.1 - 1.1e-33 116.7 19.5 1.1e-33 116.7 19.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KXG45238.1 - 0.0014 17.1 4.1 0.0017 16.7 3.0 1.7 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF1772 PF08592.11 KXG45238.1 - 0.24 11.7 7.7 4.9 7.5 2.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) Fungal_trans PF04082.18 KXG45239.1 - 1e-17 64.1 0.1 2.1e-17 63.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3535 PF12054.8 KXG45241.1 - 2e-125 419.4 0.0 9.7e-125 417.2 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KXG45241.1 - 2.4e-59 200.8 0.0 5.7e-59 199.6 0.0 1.5 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXG45241.1 - 6.8e-19 68.3 0.0 1.8e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KXG45241.1 - 5e-16 57.4 11.0 0.13 12.5 0.0 9.5 9 0 0 9 9 8 5 HEAT repeat Vac14_Fab1_bd PF12755.7 KXG45241.1 - 3.1e-07 30.9 0.1 0.079 13.6 0.0 4.0 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 KXG45241.1 - 2.4e-06 27.8 8.8 0.027 14.9 0.2 6.7 5 1 1 6 6 6 1 HEAT repeats Cnd1 PF12717.7 KXG45241.1 - 0.00027 21.0 0.1 0.14 12.2 0.0 4.2 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 KXG45241.1 - 0.00079 19.7 0.0 2.2 8.7 0.0 4.7 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain TIP120 PF08623.10 KXG45241.1 - 0.00083 19.2 0.1 0.48 10.2 0.0 3.4 2 1 1 3 3 3 1 TATA-binding protein interacting (TIP20) CLASP_N PF12348.8 KXG45241.1 - 0.01 15.4 0.3 4.4 6.8 0.0 3.9 4 1 1 5 5 5 0 CLASP N terminal HEAT_EZ PF13513.6 KXG45241.1 - 0.53 10.8 16.6 37 5.0 0.0 7.1 8 0 0 8 8 7 0 HEAT-like repeat Ndufs5 PF10200.9 KXG45242.1 - 0.00086 19.5 0.0 0.001 19.3 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 KXG45242.1 - 0.0074 16.6 1.1 0.048 14.0 1.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.17 KXG45242.1 - 0.0081 16.4 0.2 0.012 15.8 0.2 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 KXG45242.1 - 0.0095 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 CHCH domain Sec39 PF08314.11 KXG45243.1 - 9.6e-275 913.8 2.6 1.1e-274 913.6 2.6 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Pkinase PF00069.25 KXG45244.1 - 1.9e-64 217.6 0.0 2.3e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG45244.1 - 4.5e-36 124.5 0.0 5.9e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG45244.1 - 1.3e-07 31.2 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXG45244.1 - 2.5e-05 23.3 0.0 3.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KXG45244.1 - 0.021 14.4 0.0 0.85 9.2 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KXG45244.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IclR PF01614.18 KXG45247.1 - 0.0066 16.3 0.0 0.0085 15.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator EFG_C PF00679.24 KXG45247.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor G C-terminus TPR_2 PF07719.17 KXG45248.1 - 1e-35 119.0 8.7 2.4e-06 27.2 0.2 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 KXG45248.1 - 8.2e-35 117.2 10.5 8e-09 34.9 0.4 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.31 KXG45248.1 - 1.6e-26 92.2 1.6 6.8e-26 90.2 1.6 2.2 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 KXG45248.1 - 2e-23 82.7 14.0 0.00011 22.6 0.3 6.1 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXG45248.1 - 7.4e-21 74.5 7.9 1.7e-07 31.7 0.0 5.8 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXG45248.1 - 2.8e-18 65.0 8.3 0.042 14.7 0.2 8.2 2 2 6 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KXG45248.1 - 2.9e-18 65.3 15.4 1.6e-07 30.8 0.4 7.1 4 2 3 7 7 7 5 TPR repeat TPR_8 PF13181.6 KXG45248.1 - 4.1e-18 64.0 8.1 1.8e-05 24.5 0.2 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXG45248.1 - 9.4e-18 63.3 10.3 0.0017 18.6 0.4 6.4 6 0 0 6 6 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG45248.1 - 2.5e-15 56.4 2.1 6.1e-05 23.2 0.0 4.4 3 3 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KXG45248.1 - 7.2e-13 48.5 3.7 0.0036 17.4 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXG45248.1 - 1e-12 47.1 3.2 0.25 11.4 0.0 7.0 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXG45248.1 - 1.5e-11 44.4 6.0 0.02 15.1 0.2 6.3 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXG45248.1 - 6.6e-10 39.0 13.3 0.087 13.5 0.4 7.6 7 1 0 8 8 6 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXG45248.1 - 6.2e-07 29.4 9.6 0.027 14.5 0.3 5.1 5 1 1 6 6 6 3 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 KXG45248.1 - 9.3e-07 28.3 4.4 0.041 13.1 0.2 4.4 2 1 3 5 5 5 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KXG45248.1 - 0.00017 22.1 2.7 6.3 7.2 0.0 4.7 2 2 3 5 5 5 0 Alkyl sulfatase dimerisation DUF4919 PF16266.5 KXG45248.1 - 0.0011 18.9 1.3 1 9.3 0.1 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4919) DUF928 PF06051.12 KXG45248.1 - 0.0013 18.6 0.2 0.57 10.0 0.0 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF928) DUF3856 PF12968.7 KXG45248.1 - 0.0028 17.7 2.2 1.7 8.7 0.5 4.8 3 2 0 4 4 4 1 Domain of Unknown Function (DUF3856) BTAD PF03704.17 KXG45248.1 - 0.0047 17.4 2.6 3.6 8.0 0.4 3.9 2 1 0 3 3 3 1 Bacterial transcriptional activator domain TPR_4 PF07721.14 KXG45248.1 - 0.0048 17.4 3.5 8 7.4 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF627 PF04781.12 KXG45248.1 - 0.0091 16.0 0.1 0.89 9.6 0.1 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF627) SHNi-TPR PF10516.9 KXG45248.1 - 0.016 14.6 1.3 3.3 7.2 0.0 4.0 5 0 0 5 5 4 0 SHNi-TPR TPR_10 PF13374.6 KXG45248.1 - 0.016 15.0 11.4 3.8 7.5 0.3 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat MIT PF04212.18 KXG45248.1 - 0.018 15.1 8.0 9.4 6.4 0.1 4.8 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain NARP1 PF12569.8 KXG45248.1 - 0.052 12.5 3.7 0.89 8.4 0.1 3.2 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 PPR PF01535.20 KXG45248.1 - 0.067 13.5 0.6 7.1 7.1 0.1 3.8 5 0 0 5 5 2 0 PPR repeat RPT PF13446.6 KXG45248.1 - 0.084 12.8 0.6 0.84 9.6 0.0 2.9 3 0 0 3 3 2 0 A repeated domain in UCH-protein HEAT_2 PF13646.6 KXG45248.1 - 0.18 12.2 2.6 1 9.8 0.3 2.6 2 0 0 2 2 2 0 HEAT repeats TPR_20 PF14561.6 KXG45248.1 - 0.66 10.4 12.3 4 7.8 0.0 5.3 5 1 1 6 6 4 0 Tetratricopeptide repeat RAP1 PF07218.11 KXG45248.1 - 4.8 5.3 12.7 7.4 4.7 12.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.25 KXG45250.1 - 2.9e-41 141.6 0.0 4.2e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG45250.1 - 2.4e-29 102.4 0.0 3.4e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3632 PF12311.8 KXG45251.1 - 5.4e-29 101.8 0.0 8.5e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Med10 PF09748.9 KXG45252.1 - 1.8e-43 147.3 0.0 2.1e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 KXG45252.1 - 0.066 13.1 0.0 0.07 13.0 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) ILVD_EDD PF00920.21 KXG45253.1 - 2.7e-155 517.9 0.0 3.6e-155 517.5 0.0 1.2 1 0 0 1 1 1 1 Dehydratase family Fungal_trans PF04082.18 KXG45253.1 - 7.7e-23 80.9 1.1 1.2e-22 80.2 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Erythro_esteras PF05139.14 KXG45254.1 - 2.2e-124 415.8 2.3 2.5e-124 415.6 2.3 1.0 1 0 0 1 1 1 1 Erythromycin esterase Scs3p PF10261.9 KXG45256.1 - 3.1e-71 239.8 5.6 3.8e-71 239.5 5.6 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Mito_carr PF00153.27 KXG45257.1 - 1.2e-56 188.6 3.4 1.7e-19 69.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GTP_EFTU PF00009.27 KXG45258.1 - 8.4e-30 103.8 2.9 2.4e-28 99.0 2.9 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KXG45258.1 - 8.5e-29 99.8 2.2 3e-28 98.0 1.1 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 IF2_N PF04760.15 KXG45258.1 - 1.5e-09 37.5 0.0 3.6e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 KXG45258.1 - 2.7e-09 37.1 0.1 9.5e-09 35.3 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXG45258.1 - 0.00018 21.4 0.2 0.078 12.9 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KXG45258.1 - 0.009 15.5 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit zf-RanBP PF00641.18 KXG45258.1 - 0.013 14.8 2.0 0.026 13.8 2.0 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others GTP_EFTU_D2 PF03144.25 KXG45258.1 - 0.11 12.9 0.9 12 6.4 0.0 2.8 2 0 0 2 2 2 0 Elongation factor Tu domain 2 AAA_23 PF13476.6 KXG45258.1 - 0.48 10.9 6.6 11 6.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain zf-C3HC4_3 PF13920.6 KXG45258.1 - 0.61 10.0 2.5 1.1 9.1 2.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.9 KXG45258.1 - 2 8.6 4.6 4.4 7.5 4.6 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 EI24 PF07264.11 KXG45259.1 - 2.6e-13 50.6 14.5 4.4e-13 49.9 14.5 1.4 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Zn_clus PF00172.18 KXG45259.1 - 1.2e-08 34.9 9.4 2.9e-08 33.7 9.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXG45259.1 - 3.4e-05 23.0 0.0 6.5e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain HAD_2 PF13419.6 KXG45260.1 - 1.2e-10 41.7 0.0 1.6e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXG45260.1 - 1.5e-06 28.1 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KXG45260.1 - 0.0012 19.2 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ceramidase_alk PF04734.13 KXG45263.1 - 4.4e-214 711.8 0.0 5.2e-214 711.6 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KXG45263.1 - 4.2e-59 199.2 0.0 6.6e-59 198.5 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal COX16 PF14138.6 KXG45263.1 - 0.85 10.2 2.1 0.87 10.1 0.0 2.1 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 BCAS2 PF05700.11 KXG45264.1 - 1.1e-57 195.0 2.9 1.3e-57 194.8 2.9 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) 3Beta_HSD PF01073.19 KXG45265.1 - 1.1e-26 93.5 0.0 3.4e-26 91.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXG45265.1 - 1.1e-12 47.6 0.0 1.9e-10 40.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.21 KXG45265.1 - 2.1e-12 47.0 0.0 4.5e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXG45265.1 - 2.2e-07 31.0 0.0 1.4e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXG45265.1 - 0.00022 20.5 0.0 0.00038 19.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXG45265.1 - 0.0021 17.5 0.0 0.0041 16.6 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXG45265.1 - 0.005 16.0 0.0 0.24 10.5 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 KXG45265.1 - 0.026 14.4 0.9 0.29 11.0 0.9 2.2 1 1 0 1 1 1 0 KR domain NmrA PF05368.13 KXG45265.1 - 0.045 13.3 0.1 0.32 10.5 0.1 2.2 1 1 0 1 1 1 0 NmrA-like family MFS_1 PF07690.16 KXG45266.1 - 4.5e-40 137.7 35.2 4.5e-40 137.7 35.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG45266.1 - 4.4e-14 52.2 13.9 7.2e-14 51.5 13.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KXG45266.1 - 3.2e-10 39.1 6.5 5.7e-10 38.2 6.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ten1 PF12658.7 KXG45267.1 - 6.5e-44 148.8 0.0 7.4e-44 148.6 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 KXG45267.1 - 0.0029 17.3 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Snf7 PF03357.21 KXG45268.1 - 1.2e-34 119.4 19.2 1.2e-34 119.4 19.2 2.0 1 1 1 2 2 2 1 Snf7 Calici_MSP PF05752.11 KXG45268.1 - 1.7 8.4 6.9 2.7 7.8 5.9 1.8 1 1 0 1 1 1 0 Calicivirus minor structural protein NuA4 PF09340.10 KXG45268.1 - 6.8 6.6 9.1 0.48 10.3 0.3 3.2 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 CRC_subunit PF08624.10 KXG45269.1 - 3.6e-51 173.1 0.0 5.2e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit SPESP1 PF15754.5 KXG45269.1 - 0.55 9.4 8.9 1.3 8.2 8.9 1.6 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Pkinase PF00069.25 KXG45271.1 - 3.1e-69 233.3 0.0 4.2e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG45271.1 - 9.9e-31 107.0 0.0 1.5e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KXG45271.1 - 3.1e-14 53.4 0.4 2.2e-13 50.7 0.4 2.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KXG45271.1 - 7.3e-09 35.4 0.1 6.3e-08 32.3 0.0 2.0 1 1 0 2 2 2 1 Kinase-like C2 PF00168.30 KXG45271.1 - 1.7e-08 34.7 0.0 3.5e-07 30.4 0.0 2.5 2 0 0 2 2 2 1 C2 domain Haspin_kinase PF12330.8 KXG45271.1 - 1.8e-05 23.9 0.1 3.7e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXG45271.1 - 0.0052 16.7 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Adeno_E3_15_3 PF03307.14 KXG45271.1 - 0.027 14.4 0.1 0.05 13.5 0.1 1.3 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region Choline_kinase PF01633.20 KXG45271.1 - 0.066 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KXG45271.1 - 0.12 11.7 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 KXG45272.1 - 4.6e-39 134.3 24.1 4.6e-39 134.3 24.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG45272.1 - 2.5e-08 33.2 24.8 6e-08 32.0 24.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter LRR_8 PF13855.6 KXG45273.1 - 1.1 9.0 7.3 0.62 9.9 2.5 2.7 2 0 0 2 2 2 0 Leucine rich repeat tRNA-synt_1c PF00749.21 KXG45274.1 - 3.7e-102 341.4 0.0 4.8e-102 341.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KXG45274.1 - 7.8e-32 110.5 0.0 2.8e-31 108.7 0.0 2.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain THUMP PF02926.17 KXG45274.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 THUMP domain AAA PF00004.29 KXG45275.1 - 1.3e-40 138.9 0.0 2.6e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXG45275.1 - 6.9e-19 67.6 0.2 1.4e-18 66.6 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KXG45275.1 - 1.8e-09 37.3 0.0 3.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KXG45275.1 - 6.4e-05 22.8 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXG45275.1 - 9.4e-05 22.4 0.9 0.00028 20.9 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXG45275.1 - 0.00017 22.0 1.3 0.022 15.1 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KXG45275.1 - 0.004 16.4 0.0 0.011 14.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KXG45275.1 - 0.005 17.1 2.0 0.2 11.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain PhoH PF02562.16 KXG45275.1 - 0.0051 16.3 0.2 0.079 12.4 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KXG45275.1 - 0.0077 15.6 0.1 0.021 14.2 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KXG45275.1 - 0.009 16.1 3.7 0.012 15.7 0.0 3.0 3 2 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KXG45275.1 - 0.014 15.5 0.0 0.043 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXG45275.1 - 0.07 12.9 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KXG45275.1 - 0.075 12.8 0.2 0.32 10.7 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KXG45275.1 - 0.47 10.2 0.0 0.47 10.2 0.0 2.9 2 1 0 3 3 2 0 AAA domain Atg14 PF10186.9 KXG45275.1 - 2.2 7.3 7.4 7.3 5.6 6.9 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CLZ PF16526.5 KXG45275.1 - 3.1 8.2 11.5 0.75 10.2 6.9 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TauD PF02668.16 KXG45276.1 - 2.2e-37 129.3 1.2 4.2e-37 128.4 1.2 1.5 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MaoC_dehydratas PF01575.19 KXG45276.1 - 1.1e-22 79.9 0.0 2.3e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KXG45276.1 - 2.3e-06 27.8 0.0 0.11 12.6 0.0 3.6 3 0 0 3 3 3 2 N-terminal half of MaoC dehydratase DUF971 PF06155.12 KXG45276.1 - 0.0019 18.8 0.0 0.0049 17.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KXG45276.1 - 0.035 13.2 0.1 0.078 12.1 0.1 1.5 1 1 0 1 1 1 0 CsiD Methyltransf_25 PF13649.6 KXG45277.1 - 1.1e-12 48.5 0.0 2.6e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG45277.1 - 1.2e-11 44.7 0.0 2.5e-11 43.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXG45277.1 - 1.4e-10 41.0 0.0 2.1e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KXG45277.1 - 7.1e-09 36.2 0.0 2.6e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG45277.1 - 5.6e-08 32.8 0.0 8.7e-07 28.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KXG45277.1 - 3.7e-06 26.1 0.0 6.7e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 KXG45277.1 - 1.9e-05 24.1 0.0 2.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KXG45277.1 - 0.00012 22.1 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXG45277.1 - 0.00023 20.8 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KXG45277.1 - 0.00058 20.6 0.0 0.0012 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KXG45277.1 - 0.002 18.3 0.0 0.0053 16.9 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KXG45277.1 - 0.0035 17.1 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase TehB PF03848.14 KXG45277.1 - 0.0061 16.0 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 KXG45277.1 - 0.0095 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 KXG45277.1 - 0.015 15.2 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Ubie_methyltran PF01209.18 KXG45277.1 - 0.02 14.2 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KXG45277.1 - 0.025 14.3 0.2 0.044 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 KXG45277.1 - 0.067 14.2 0.0 0.15 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Per1 PF04080.13 KXG45278.1 - 5.6e-102 340.9 14.2 6.8e-102 340.6 14.2 1.1 1 0 0 1 1 1 1 Per1-like family SPC25 PF06703.11 KXG45278.1 - 0.19 11.5 0.9 0.38 10.5 0.9 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) PGM_PMM_I PF02878.16 KXG45279.1 - 9.9e-16 57.7 0.1 3.3e-07 30.1 0.0 2.8 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KXG45279.1 - 2.1e-11 43.8 0.8 8.1e-11 41.9 0.3 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 KXG45279.1 - 0.001 19.7 1.0 0.0072 16.9 0.6 2.6 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KXG45279.1 - 0.0013 18.9 0.2 0.0067 16.6 0.2 2.1 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DEAD PF00270.29 KXG45280.1 - 8.6e-46 155.9 0.0 1.2e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG45280.1 - 1.2e-28 99.6 0.0 3.9e-28 98.0 0.0 1.9 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXG45280.1 - 9.8e-05 21.7 0.0 0.0002 20.6 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KXG45280.1 - 0.00082 19.4 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Brix PF04427.18 KXG45281.1 - 5e-51 173.6 0.7 7e-51 173.1 0.7 1.2 1 0 0 1 1 1 1 Brix domain MRNIP PF15749.5 KXG45281.1 - 6.5 7.5 10.5 0.94 10.2 5.3 2.3 2 0 0 2 2 2 0 MRN-interacting protein Lum_binding PF00677.17 KXG45282.1 - 1.8e-43 146.4 1.3 5.9e-22 77.5 0.4 2.2 2 0 0 2 2 2 2 Lumazine binding domain CoA_transf_3 PF02515.17 KXG45283.1 - 7.6e-129 430.0 0.0 8.7e-129 429.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III GxDLY PF14607.6 KXG45283.1 - 0.13 12.1 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 N-terminus of Esterase_SGNH_hydro-type PHD PF00628.29 KXG45284.1 - 4.6e-09 36.0 7.5 8.1e-09 35.2 7.5 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KXG45284.1 - 0.0038 17.1 3.3 0.0077 16.1 3.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 Cytochrom_c3_2 PF14537.6 KXG45284.1 - 0.04 14.4 2.1 0.42 11.1 0.1 2.4 2 0 0 2 2 2 0 Cytochrome c3 adh_short PF00106.25 KXG45285.1 - 4.7e-31 107.8 0.0 7.2e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG45285.1 - 1.3e-22 80.5 0.0 2e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG45285.1 - 5.1e-08 33.0 0.2 1.3e-07 31.8 0.2 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXG45285.1 - 0.0089 15.4 0.0 0.022 14.2 0.0 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Sof1 PF04158.14 KXG45286.1 - 1.2e-30 105.7 15.3 2.2e-30 104.8 15.3 1.5 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KXG45286.1 - 2.1e-30 104.3 3.5 8.5e-06 26.4 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG45286.1 - 7.3e-09 35.8 0.2 0.067 13.5 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXG45286.1 - 4e-05 22.7 0.1 0.019 13.9 0.0 2.9 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXG45286.1 - 0.0014 18.6 0.4 0.0039 17.1 0.1 1.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KXG45286.1 - 0.0024 16.3 0.0 0.0081 14.5 0.0 1.8 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz RPN6_N PF18055.1 KXG45287.1 - 3.2e-42 143.6 0.1 1.9e-41 141.1 0.0 2.4 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain SWIB PF02201.18 KXG45287.1 - 3.1e-23 81.5 0.0 6.6e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain PCI PF01399.27 KXG45287.1 - 2.9e-21 76.0 0.2 9e-21 74.4 0.2 1.9 1 0 0 1 1 1 1 PCI domain RPN6_C_helix PF18503.1 KXG45287.1 - 1.8e-07 30.8 0.0 4.5e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 KXG45287.1 - 0.00031 20.4 0.5 0.00031 20.4 0.5 2.0 2 0 0 2 2 2 1 DDRGK domain TPR_MalT PF17874.1 KXG45287.1 - 0.0004 19.8 2.6 0.00076 19.0 2.6 1.5 1 0 0 1 1 1 1 MalT-like TPR region TPR_12 PF13424.6 KXG45287.1 - 0.0025 18.0 16.8 0.75 10.1 6.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat HTH_Crp_2 PF13545.6 KXG45287.1 - 0.0084 16.1 0.0 1.1 9.3 0.0 2.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain DUF410 PF04190.13 KXG45287.1 - 0.0092 15.8 0.1 0.03 14.1 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_1 PF00515.28 KXG45287.1 - 0.47 10.4 2.8 4.1 7.4 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXG45287.1 - 0.73 10.2 2.7 44 4.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXG45287.1 - 0.85 9.9 5.6 21 5.5 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TRAM_LAG1_CLN8 PF03798.16 KXG45288.1 - 1.5e-54 184.8 14.9 2.5e-54 184.0 14.9 1.3 1 0 0 1 1 1 1 TLC domain DUF2157 PF09925.9 KXG45288.1 - 1.7 8.4 9.0 3.2 7.5 9.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Chalcone_3 PF16036.5 KXG45289.1 - 0.033 14.3 9.8 1.2 9.2 0.1 6.1 4 1 0 4 4 4 0 Chalcone isomerase-like Ish1 PF10281.9 KXG45289.1 - 0.067 13.5 3.6 1.7e+02 2.6 0.0 7.1 7 0 0 7 7 7 0 Putative stress-responsive nuclear envelope protein HEPN_RES_NTD1 PF18870.1 KXG45289.1 - 0.26 11.5 4.0 51 4.1 0.0 4.8 3 1 1 4 4 4 0 HEPN/RES N-terminal domain 1 Scaffolding_pro PF11418.8 KXG45289.1 - 2.7 8.6 7.9 0.79 10.3 0.8 4.1 4 0 0 4 4 4 0 Phi29 scaffolding protein DUF1269 PF06897.12 KXG45289.1 - 5.4 7.4 8.5 12 6.2 0.7 5.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1269) Ribosomal_L27e PF01777.18 KXG45290.1 - 4.2e-35 120.0 0.9 6.9e-35 119.3 0.9 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KXG45290.1 - 0.01 15.8 2.9 0.014 15.3 1.5 2.0 2 0 0 2 2 2 0 KOW motif MAGE PF01454.19 KXG45293.1 - 9e-61 205.3 0.0 1.4e-60 204.7 0.0 1.3 1 0 0 1 1 1 1 MAGE family GTP_EFTU PF00009.27 KXG45294.1 - 4.5e-54 182.9 0.0 6.8e-54 182.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXG45294.1 - 6.5e-42 142.4 0.0 1.7e-41 141.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXG45294.1 - 1.7e-12 47.6 0.6 5e-12 46.0 0.6 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXG45294.1 - 0.00021 21.4 0.2 0.0064 16.6 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Semialdhyde_dhC PF02774.18 KXG45294.1 - 0.032 14.3 0.1 0.32 11.1 0.1 2.2 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain FlpD PF02662.16 KXG45294.1 - 0.062 13.3 0.0 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit GTP_EFTU_D4 PF14578.6 KXG45294.1 - 0.14 12.1 2.9 0.094 12.6 0.7 1.8 2 0 0 2 2 2 0 Elongation factor Tu domain 4 G-alpha PF00503.20 KXG45294.1 - 0.17 11.0 0.1 0.63 9.1 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit TFIIS_C PF01096.18 KXG45295.1 - 5.3e-20 71.0 2.4 5.3e-20 71.0 2.4 3.0 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KXG45295.1 - 2e-08 34.0 5.2 2.6e-07 30.4 1.8 3.3 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit IBR PF01485.21 KXG45295.1 - 0.0018 18.4 5.4 0.55 10.5 0.7 2.4 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain Zn_ribbon_recom PF13408.6 KXG45295.1 - 0.025 15.1 0.2 1.5 9.4 0.0 2.5 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_4 PF13717.6 KXG45295.1 - 0.075 13.0 7.8 1.7 8.6 0.2 3.0 3 1 0 3 3 3 0 zinc-ribbon domain PriA_CRR PF18319.1 KXG45295.1 - 0.095 12.7 1.8 2.8 8.0 0.1 3.1 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain zf-H2C2_2 PF13465.6 KXG45295.1 - 0.8 10.2 6.6 5.1 7.7 0.1 3.7 4 0 0 4 4 4 0 Zinc-finger double domain DZR PF12773.7 KXG45295.1 - 1.4 9.0 7.2 0.93 9.6 0.4 2.7 2 1 0 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 KXG45295.1 - 2.6 7.6 8.5 3.1 7.4 0.4 2.9 3 1 0 3 3 3 0 TFIIB zinc-binding zf-TFIIB PF13453.6 KXG45295.1 - 4.4 6.7 8.4 0.71 9.3 0.7 3.0 3 0 0 3 3 3 0 Transcription factor zinc-finger Ank_3 PF13606.6 KXG45296.1 - 5.2e-08 32.5 0.0 0.012 16.0 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KXG45296.1 - 3.1e-07 30.9 0.1 1.4e-06 28.8 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXG45296.1 - 2.4e-06 27.7 0.1 0.0054 17.0 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXG45296.1 - 3.4e-05 24.1 0.0 0.038 14.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KXG45296.1 - 4.6e-05 23.9 0.7 0.0017 18.9 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PPR_long PF17177.4 KXG45296.1 - 0.005 16.2 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP ALG11_N PF15924.5 KXG45297.1 - 1.9e-83 279.7 0.1 2.6e-83 279.2 0.1 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KXG45297.1 - 2.1e-21 76.2 0.0 3.7e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXG45297.1 - 5.7e-11 43.0 0.0 3.4e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXG45297.1 - 7e-05 22.9 0.0 0.00029 20.9 0.0 2.1 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KXG45297.1 - 0.0083 16.5 0.1 0.018 15.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 AAA_5 PF07728.14 KXG45297.1 - 0.02 14.9 0.1 0.058 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) 60KD_IMP PF02096.20 KXG45298.1 - 4.6e-11 42.9 1.2 2.6e-09 37.2 1.4 2.1 2 0 0 2 2 2 2 60Kd inner membrane protein ABC_tran_Xtn PF12848.7 KXG45298.1 - 0.034 14.2 2.6 0.062 13.3 2.6 1.3 1 0 0 1 1 1 0 ABC transporter PP2C PF00481.21 KXG45299.1 - 1e-43 149.8 0.0 2e-43 148.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KXG45299.1 - 0.00068 19.3 0.2 0.0015 18.2 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 KXG45299.1 - 0.003 17.5 0.0 2.2 8.2 0.0 3.1 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Tcf25 PF04910.14 KXG45300.1 - 1.2e-75 254.8 0.0 1.6e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DUF3381 PF11861.8 KXG45300.1 - 1.8 8.3 17.6 3.5 7.4 17.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PGA2 PF07543.12 KXG45300.1 - 2.1 8.3 17.4 3.7 7.5 17.4 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 CDC45 PF02724.14 KXG45300.1 - 4.3 5.5 10.6 5.6 5.1 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PQ-loop PF04193.14 KXG45301.1 - 2.3e-38 129.7 4.4 1.1e-19 69.9 0.2 2.7 2 0 0 2 2 2 2 PQ loop repeat Ribosomal_60s PF00428.19 KXG45302.1 - 7.2e-26 90.6 11.4 8.5e-26 90.4 11.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein WRNPLPNID PF15017.6 KXG45302.1 - 0.039 14.8 0.1 0.057 14.3 0.1 1.2 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box DUF2408 PF10303.9 KXG45303.1 - 3.2e-44 150.8 7.1 1.6e-28 99.9 1.1 5.1 3 2 2 5 5 5 3 Protein of unknown function (DUF2408) Spc7 PF08317.11 KXG45303.1 - 7.4e-05 21.8 0.2 0.00015 20.8 0.2 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein FPP PF05911.11 KXG45303.1 - 0.0014 17.0 0.4 0.0019 16.5 0.4 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DNA_pol_phi PF04931.13 KXG45303.1 - 0.0039 15.4 0.6 0.0052 15.0 0.6 1.1 1 0 0 1 1 1 1 DNA polymerase phi DUF2383 PF09537.10 KXG45303.1 - 0.0058 17.0 0.2 0.027 14.8 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2383) EzrA PF06160.12 KXG45303.1 - 0.0091 14.2 0.4 0.35 9.0 0.5 2.1 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA ABC_tran_CTD PF16326.5 KXG45303.1 - 0.013 15.8 3.0 4.7 7.5 0.1 4.2 4 0 0 4 4 4 0 ABC transporter C-terminal domain CKAP2_C PF15297.6 KXG45303.1 - 0.051 12.7 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus HrpB7 PF09486.10 KXG45303.1 - 0.06 13.7 0.1 0.23 11.8 0.1 1.9 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) PTRF_SDPR PF15237.6 KXG45303.1 - 0.077 12.6 0.3 0.17 11.5 0.3 1.5 1 0 0 1 1 1 0 PTRF/SDPR family Snapin_Pallidin PF14712.6 KXG45303.1 - 0.085 13.3 5.0 0.53 10.7 0.5 3.9 4 0 0 4 4 4 0 Snapin/Pallidin Peptidase_M75 PF09375.10 KXG45303.1 - 0.087 12.3 0.2 0.15 11.5 0.2 1.4 1 0 0 1 1 1 0 Imelysin LOH1CR12 PF10158.9 KXG45303.1 - 0.12 12.4 0.4 3.3 7.7 0.1 2.5 2 0 0 2 2 2 0 Tumour suppressor protein HsbA PF12296.8 KXG45303.1 - 0.15 12.5 0.7 0.35 11.3 0.3 1.8 2 0 0 2 2 1 0 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.12 KXG45303.1 - 0.2 11.7 2.1 0.29 11.2 0.8 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus THOC7 PF05615.13 KXG45303.1 - 0.45 10.8 5.4 0.6 10.4 0.9 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 ATG16 PF08614.11 KXG45303.1 - 0.54 10.4 5.4 0.26 11.5 2.4 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Prefoldin_2 PF01920.20 KXG45303.1 - 2.3 8.2 8.9 12 5.9 0.3 3.6 2 1 2 4 4 4 0 Prefoldin subunit Aconitase PF00330.20 KXG45305.1 - 1.7e-143 479.0 0.0 2.1e-143 478.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXG45305.1 - 4.5e-38 130.5 0.0 7e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2 PF00096.26 KXG45306.1 - 1.8e-12 47.0 12.6 3.8e-06 27.0 2.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXG45306.1 - 6.3e-12 45.4 9.7 2e-07 31.1 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXG45306.1 - 9.4e-09 35.4 10.4 0.00043 20.9 1.5 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXG45306.1 - 3.9e-08 33.1 5.4 0.00034 20.5 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXG45306.1 - 3.6e-06 27.1 0.4 0.093 13.0 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXG45306.1 - 0.00048 20.4 5.1 0.014 15.8 0.2 3.6 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KXG45306.1 - 0.0063 16.3 4.8 0.43 10.4 0.7 3.4 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-Di19 PF05605.12 KXG45306.1 - 0.086 13.1 1.4 0.19 12.0 1.4 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.6 KXG45306.1 - 0.19 12.2 0.9 0.44 11.1 0.9 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2HE PF16278.5 KXG45306.1 - 0.35 11.3 1.9 12 6.5 0.3 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 KXG45306.1 - 0.78 10.0 3.1 19 5.6 0.1 2.5 1 1 1 2 2 2 0 LIM domain C5HCH PF17982.1 KXG45306.1 - 5.8 7.1 6.0 30 4.9 0.4 2.6 1 1 1 2 2 2 0 NSD Cys-His rich domain Glyco_hydro_53 PF07745.13 KXG45307.1 - 1.8e-102 342.8 0.8 2.1e-102 342.6 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Pkinase PF00069.25 KXG45308.1 - 1.2e-52 179.0 0.3 6.8e-35 120.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG45308.1 - 1.9e-28 99.5 0.0 5.9e-27 94.6 0.0 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXG45308.1 - 0.0013 17.6 0.0 0.0013 17.6 0.0 2.1 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 KXG45308.1 - 0.0018 17.6 0.0 0.0058 16.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXG45308.1 - 0.13 12.1 7.1 0.03 14.3 0.8 2.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kelch_4 PF13418.6 KXG45309.1 - 4.2e-06 26.7 0.1 0.017 15.1 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KXG45309.1 - 4.7e-06 26.7 1.4 0.47 10.8 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 KXG45309.1 - 2.6e-05 24.1 0.1 0.0057 16.6 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 KXG45309.1 - 0.00013 22.1 6.8 0.1 12.9 0.2 4.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KXG45309.1 - 0.00066 19.6 0.0 0.37 10.9 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 KXG45309.1 - 0.0014 18.2 0.0 3.3 7.4 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Chorismate_synt PF01264.21 KXG45310.1 - 6.2e-139 462.3 0.0 7.1e-139 462.1 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase BPL_LplA_LipB PF03099.19 KXG45311.1 - 1.1e-07 31.8 0.0 2.9e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF2264 PF10022.9 KXG45312.1 - 1e-139 465.5 0.1 1.3e-139 465.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Sugar_tr PF00083.24 KXG45313.1 - 2.1e-120 402.7 26.2 2.4e-120 402.5 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG45313.1 - 9.9e-15 54.3 45.7 1.4e-13 50.5 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Alg14 PF08660.11 KXG45315.1 - 1.3e-55 188.1 0.0 1.8e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Orexin PF02072.15 KXG45315.1 - 0.014 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Prepro-orexin adh_short_C2 PF13561.6 KXG45316.1 - 1.4e-44 152.4 0.1 1.7e-44 152.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG45316.1 - 1.6e-41 141.9 0.0 2.2e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG45316.1 - 3e-12 46.8 0.1 1.7e-11 44.3 0.1 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXG45316.1 - 0.0034 16.9 0.0 0.0098 15.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Formyl_trans_N PF00551.19 KXG45317.1 - 6.2e-22 78.2 0.0 1.2e-21 77.3 0.0 1.5 1 1 0 1 1 1 1 Formyl transferase PBP_N PF17093.5 KXG45317.1 - 0.1 12.9 0.2 0.21 11.8 0.2 1.4 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus DUF1712 PF08217.11 KXG45318.1 - 3.5e-14 52.2 0.0 1.9e-11 43.2 0.0 2.4 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Ras PF00071.22 KXG45319.1 - 1.7e-56 190.3 0.0 2e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXG45319.1 - 6e-22 78.1 0.0 8.5e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG45319.1 - 3.2e-07 29.9 0.0 5.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXG45319.1 - 0.00062 19.3 0.0 0.00083 18.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KXG45319.1 - 0.0011 18.5 0.0 0.003 17.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 KXG45319.1 - 0.055 12.6 0.1 0.55 9.4 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 KXG45319.1 - 0.061 12.7 0.0 0.075 12.4 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region KOW PF00467.29 KXG45320.1 - 0.0016 18.3 0.5 0.0029 17.5 0.5 1.4 1 0 0 1 1 1 1 KOW motif SOR_SNZ PF01680.17 KXG45320.1 - 0.004 17.0 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 SOR/SNZ family FAO_M PF16350.5 KXG45320.1 - 0.031 14.6 2.1 0.054 13.8 0.6 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase central domain Rtt106 PF08512.12 KXG45321.1 - 2.4e-30 104.8 0.1 2.1e-29 101.8 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KXG45321.1 - 9.1e-05 22.5 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Vfa1 PF08432.10 KXG45321.1 - 4.3 7.6 8.1 9 6.6 8.1 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Cwf_Cwc_15 PF04889.12 KXG45321.1 - 5 6.8 21.9 8.9 6.0 21.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 KXG45321.1 - 7.3 6.1 15.1 14 5.1 15.1 1.5 1 0 0 1 1 1 0 PPP4R2 Pkinase PF00069.25 KXG45322.1 - 7.3e-28 97.7 0.0 9.1e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG45322.1 - 1.6e-14 53.8 0.0 2.1e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXG45322.1 - 4.4e-07 29.0 0.0 6.5e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RGS PF00615.19 KXG45323.1 - 8.2e-13 48.7 0.0 1.5e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF647 PF04884.14 KXG45324.1 - 1.8e-106 355.2 1.7 1.8e-106 355.2 1.7 1.9 3 0 0 3 3 3 1 Vitamin B6 photo-protection and homoeostasis DUF5342 PF17277.2 KXG45324.1 - 0.0047 17.2 0.3 0.044 14.1 0.1 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5342) S36_mt PF10937.8 KXG45325.1 - 1.2e-39 136.4 0.2 1.5e-39 136.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial Med18 PF09637.10 KXG45326.1 - 3e-62 210.7 0.0 3.5e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 Med18 protein PNK3P PF08645.11 KXG45327.1 - 2.7e-54 183.3 0.0 4.1e-54 182.7 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KXG45327.1 - 9.4e-26 90.7 0.1 1.8e-22 80.1 0.1 3.2 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 KXG45327.1 - 0.00019 21.0 1.5 0.096 12.1 0.0 2.4 2 1 1 3 3 3 2 Chromatin associated protein KTI12 RsgA_GTPase PF03193.16 KXG45327.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Methyltransf_25 PF13649.6 KXG45328.1 - 8.4e-17 61.7 0.0 1.4e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG45328.1 - 6.2e-16 58.8 0.0 1.1e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG45328.1 - 1.6e-13 50.6 0.0 2.5e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KXG45328.1 - 1e-11 44.8 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG45328.1 - 2.5e-11 44.2 0.0 4e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXG45328.1 - 1.1e-05 25.1 0.1 2.8e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KXG45328.1 - 3.5e-05 23.7 0.0 4.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXG45328.1 - 0.0022 18.0 0.0 0.0032 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KXG45328.1 - 0.046 13.5 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase NAD_binding_4 PF07993.12 KXG45330.1 - 2e-41 141.9 0.0 3.4e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXG45330.1 - 1.9e-27 96.0 0.0 3e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KXG45330.1 - 6.8e-10 38.8 0.0 2.7e-09 36.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXG45330.1 - 9.1e-07 29.1 0.0 2.4e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 KXG45330.1 - 8.8e-06 25.0 0.0 0.00055 19.1 0.0 2.5 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KXG45330.1 - 0.0016 17.5 0.0 0.0053 15.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyoxalase PF00903.25 KXG45331.1 - 9.2e-14 51.7 0.0 3.1e-13 50.0 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXG45331.1 - 4.8e-05 23.6 0.0 7.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FRG1 PF06229.12 KXG45332.1 - 0.16 11.6 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 FRG1-like domain M20_dimer PF07687.14 KXG45333.1 - 5.3e-16 58.5 0.0 1.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KXG45333.1 - 1.7e-14 54.0 0.0 2.5e-13 50.2 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KXG45333.1 - 0.039 13.6 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 TPR_14 PF13428.6 KXG45333.1 - 0.059 14.2 0.6 0.2 12.5 0.6 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_hydro_47 PF01532.20 KXG45334.1 - 1.1e-163 545.4 0.1 1.3e-163 545.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AAA PF00004.29 KXG45335.1 - 6.3e-43 146.4 0.0 1.1e-42 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXG45335.1 - 1.3e-10 41.0 0.1 1.1e-09 38.1 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KXG45335.1 - 4.2e-10 39.3 0.1 8e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KXG45335.1 - 3.6e-07 30.7 0.0 0.00016 22.1 0.1 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 KXG45335.1 - 2e-06 28.0 0.0 7.5e-06 26.2 0.0 2.0 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXG45335.1 - 2.5e-06 27.5 0.1 5.5e-05 23.2 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXG45335.1 - 3e-06 27.1 0.0 6.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KXG45335.1 - 0.00025 20.3 0.0 0.00057 19.1 0.0 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KXG45335.1 - 0.00058 20.2 0.1 0.023 15.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 KXG45335.1 - 0.00087 19.8 0.0 0.0028 18.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KXG45335.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 KXG45335.1 - 0.0033 16.7 0.0 0.0072 15.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 KXG45335.1 - 0.0042 17.1 0.0 0.012 15.6 0.0 1.7 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KXG45335.1 - 0.005 16.6 0.0 0.016 14.9 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KXG45335.1 - 0.0053 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXG45335.1 - 0.0064 16.2 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KXG45335.1 - 0.0069 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_3 PF07726.11 KXG45335.1 - 0.012 15.4 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KXG45335.1 - 0.013 15.5 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXG45335.1 - 0.016 15.4 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXG45335.1 - 0.029 14.1 0.1 0.085 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 KXG45335.1 - 0.029 13.7 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_30 PF13604.6 KXG45335.1 - 0.034 13.9 0.1 0.091 12.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain Prot_ATP_OB_N PF17758.1 KXG45335.1 - 0.04 13.6 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_25 PF13481.6 KXG45335.1 - 0.04 13.5 0.1 0.1 12.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 KXG45335.1 - 0.045 13.2 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 KXG45335.1 - 0.053 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin GAS PF13851.6 KXG45335.1 - 0.076 12.4 1.1 0.16 11.3 1.1 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Parvo_NS1 PF01057.17 KXG45335.1 - 0.078 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KXG45335.1 - 0.082 13.1 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain CEP209_CC5 PF16574.5 KXG45335.1 - 0.086 13.0 1.2 0.29 11.3 1.3 1.9 1 1 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 NACHT PF05729.12 KXG45335.1 - 0.1 12.5 0.1 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 KXG45335.1 - 0.11 12.3 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain SHNi-TPR PF10516.9 KXG45335.1 - 0.2 11.1 0.4 2.5 7.7 0.2 2.6 2 0 0 2 2 2 0 SHNi-TPR Enolase_C PF00113.22 KXG45336.1 - 1.7e-152 506.8 0.0 2.3e-152 506.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KXG45336.1 - 1.6e-57 193.3 0.9 3.6e-57 192.2 0.3 1.8 2 0 0 2 2 2 1 Enolase, N-terminal domain MAAL_C PF07476.11 KXG45336.1 - 0.013 14.6 0.3 1.3 8.1 0.1 2.9 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus eIF3_subunit PF08597.10 KXG45337.1 - 1.5e-70 237.9 24.9 1.6e-70 237.8 24.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF4746 PF15928.5 KXG45337.1 - 2.8 7.3 17.3 1.3 8.4 13.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF4228 PF14009.6 KXG45337.1 - 5.6 7.3 9.2 5.7 7.3 4.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Rtf2 PF04641.12 KXG45337.1 - 7.1 5.9 17.7 1.6 8.1 8.3 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger HET PF06985.11 KXG45339.1 - 8.8e-11 42.3 0.1 4.1e-08 33.7 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) 14-3-3 PF00244.20 KXG45340.1 - 1.9e-107 357.8 0.6 2.5e-107 357.4 0.6 1.1 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 KXG45340.1 - 0.015 13.7 1.2 0.024 13.1 1.2 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF3431 PF11913.8 KXG45341.1 - 8.9e-19 68.1 0.0 1.1e-18 67.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) E1-E2_ATPase PF00122.20 KXG45342.1 - 2.1e-49 167.5 1.1 2.1e-49 167.5 1.1 3.8 5 0 0 5 5 5 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXG45342.1 - 1.3e-47 161.9 5.2 1.3e-47 161.9 5.2 3.9 4 1 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXG45342.1 - 4.1e-21 76.2 1.7 4.1e-21 76.2 1.7 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXG45342.1 - 2.2e-19 68.9 0.1 6.9e-19 67.3 0.1 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KXG45342.1 - 1.8e-17 63.2 0.0 3.2e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) MFS_1 PF07690.16 KXG45342.1 - 2.1e-17 63.1 29.0 2.1e-17 63.1 29.0 3.1 2 1 1 3 3 3 1 Major Facilitator Superfamily Hydrolase_3 PF08282.12 KXG45342.1 - 3.4e-08 33.5 2.5 9.2e-06 25.6 2.4 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXG45342.1 - 1.2e-06 29.0 0.0 4.4e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXG45342.1 - 0.094 12.8 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase baeRF_family2 PF18844.1 KXG45342.1 - 0.098 12.7 0.2 23 5.0 0.0 3.3 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 2 DUF4293 PF14126.6 KXG45342.1 - 1.5 9.1 7.8 0.15 12.3 0.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) LapA_dom PF06305.11 KXG45342.1 - 5 7.0 9.3 5.1 7.0 0.1 3.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 KXG45343.1 - 1e-66 225.0 0.0 1.6e-66 224.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG45343.1 - 2.1e-42 145.2 0.0 3e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG45343.1 - 8.9e-08 31.8 0.0 3.5e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXG45343.1 - 2.4e-06 26.8 0.1 2.4e-06 26.8 0.1 2.0 2 0 0 2 2 2 1 Haspin like kinase domain PRKG1_interact PF15898.5 KXG45343.1 - 0.0031 18.4 4.6 0.012 16.5 4.6 2.0 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain Kdo PF06293.14 KXG45343.1 - 0.015 14.7 0.2 0.038 13.3 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXG45343.1 - 0.14 12.1 4.9 0.96 9.3 0.0 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Prenyltrans PF00432.21 KXG45344.1 - 2.2e-31 107.3 11.2 5.6e-06 26.0 0.2 6.5 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KXG45344.1 - 0.0048 16.0 0.0 0.074 12.1 0.0 2.6 1 1 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain Ilm1 PF10311.9 KXG45345.1 - 1.9e-50 170.7 1.1 2.3e-50 170.5 1.1 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 CFEM PF05730.11 KXG45346.1 - 2.1e-10 40.6 12.5 2.1e-10 40.6 12.5 1.9 2 1 0 2 2 2 1 CFEM domain VHS PF00790.19 KXG45346.1 - 0.093 12.6 0.2 0.14 12.0 0.2 1.2 1 0 0 1 1 1 0 VHS domain Mucin PF01456.17 KXG45346.1 - 0.35 10.9 31.9 0.036 14.1 27.4 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein CBFD_NFYB_HMF PF00808.23 KXG45347.1 - 4.8e-29 100.4 0.6 6.6e-29 100.0 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXG45347.1 - 3.4e-06 27.4 0.0 5.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KXG45347.1 - 0.00026 21.0 0.0 0.0004 20.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KXG45347.1 - 0.00038 20.4 0.1 0.00064 19.7 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 KXG45347.1 - 0.009 16.1 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold MFS_1 PF07690.16 KXG45348.1 - 2.2e-31 109.1 26.8 2.2e-31 109.1 26.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG45348.1 - 2.2e-09 36.7 13.6 2.2e-09 36.7 13.6 3.1 3 1 0 3 3 3 1 Sugar (and other) transporter APH PF01636.23 KXG45349.1 - 2.8e-10 40.5 0.0 6.5e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family HCBP_related PF06594.11 KXG45349.1 - 0.082 12.9 0.4 4.4 7.3 0.0 3.0 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain adh_short PF00106.25 KXG45350.1 - 4.8e-21 75.1 0.2 6.3e-21 74.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG45350.1 - 1.1e-14 54.6 0.1 1.4e-14 54.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXG45350.1 - 3e-06 26.9 0.0 4.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXG45350.1 - 2.1e-05 24.5 0.5 3.3e-05 23.9 0.4 1.4 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KXG45350.1 - 2.4e-05 24.3 0.2 3.2e-05 23.9 0.2 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXG45350.1 - 0.00034 20.1 0.0 0.0012 18.4 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXG45350.1 - 0.013 15.1 0.2 0.019 14.5 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_3 PF03447.16 KXG45350.1 - 0.074 13.7 0.1 0.43 11.2 0.0 2.1 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Eisosome1 PF12757.7 KXG45352.1 - 1.6e-32 112.4 15.4 1.6e-32 112.4 15.4 2.5 3 0 0 3 3 3 1 Eisosome protein 1 PGAP1 PF07819.13 KXG45352.1 - 4.6e-05 23.2 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein ANAPC4_WD40 PF12894.7 KXG45352.1 - 5.7e-05 23.3 0.0 3.9 7.9 0.0 5.3 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF676 PF05057.14 KXG45352.1 - 0.0084 15.6 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA PF00004.29 KXG45352.1 - 0.053 14.0 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) WD40 PF00400.32 KXG45352.1 - 0.086 13.7 2.8 11 7.0 0.1 5.2 6 0 0 6 6 6 0 WD domain, G-beta repeat AAA_22 PF13401.6 KXG45352.1 - 0.16 12.2 4.3 1.4 9.2 0.1 3.5 3 1 0 3 3 3 0 AAA domain Abhydrolase_3 PF07859.13 KXG45353.1 - 5e-18 65.7 0.3 2.2e-13 50.6 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXG45353.1 - 8.6e-10 38.4 0.3 0.00026 20.5 0.0 2.3 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXG45353.1 - 7.7e-06 26.7 3.9 9.9e-06 26.3 3.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KXG45353.1 - 3e-05 23.7 0.0 0.098 12.2 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family COesterase PF00135.28 KXG45353.1 - 3.9e-05 22.7 0.0 0.00011 21.2 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S15 PF02129.18 KXG45353.1 - 5.6e-05 22.9 0.0 0.051 13.2 0.0 2.7 3 0 0 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 KXG45353.1 - 0.0002 20.1 0.1 0.056 12.1 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 KXG45353.1 - 0.006 15.9 0.1 0.11 11.7 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KXG45353.1 - 0.019 14.8 0.0 3 7.6 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF2920 PF11144.8 KXG45353.1 - 0.086 12.0 0.0 2.4 7.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) PGAP1 PF07819.13 KXG45353.1 - 0.23 11.2 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Ank_2 PF12796.7 KXG45354.1 - 2.5e-32 111.3 0.2 0.00024 21.6 0.0 8.3 7 1 1 8 8 8 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG45354.1 - 1.5e-22 77.2 9.6 0.053 14.1 0.1 12.0 13 1 1 14 14 14 5 Ankyrin repeat Ank PF00023.30 KXG45354.1 - 2e-17 62.7 13.9 0.035 14.6 0.0 9.7 10 1 1 11 11 11 5 Ankyrin repeat Ank_4 PF13637.6 KXG45354.1 - 1.3e-14 54.4 6.2 0.031 14.9 0.0 9.6 8 3 3 11 11 11 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG45354.1 - 2.2e-13 50.1 2.4 0.26 11.7 0.0 9.5 7 2 2 9 9 9 4 Ankyrin repeats (many copies) DUF3963 PF13124.6 KXG45355.1 - 0.076 13.0 0.2 0.28 11.2 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Glyco_hydro_35 PF01301.19 KXG45356.1 - 1.9e-80 270.9 4.0 2.8e-80 270.3 4.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KXG45356.1 - 1.3e-59 199.7 0.3 8.8e-33 113.3 0.0 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KXG45356.1 - 1e-52 178.6 6.4 1.9e-52 177.7 6.4 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 Y_phosphatase3 PF13350.6 KXG45356.1 - 6.4e-41 140.8 0.0 1.3e-40 139.8 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family BetaGal_dom3 PF13363.6 KXG45356.1 - 3e-22 78.0 0.3 8.8e-22 76.5 0.3 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 KXG45356.1 - 7.4e-07 28.9 1.7 0.0032 17.0 0.0 3.3 2 1 1 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Y_phosphatase2 PF03162.13 KXG45356.1 - 2e-06 27.5 0.0 3.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KXG45356.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Frag1 PF10277.9 KXG45357.1 - 3e-43 147.9 11.2 3.4e-43 147.7 11.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family CPP1-like PF11833.8 KXG45357.1 - 0.23 11.1 0.9 0.43 10.2 0.4 1.7 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Ninjurin PF04923.12 KXG45357.1 - 0.61 10.1 5.1 4.1 7.4 0.1 2.9 2 1 1 3 3 3 0 Ninjurin Tmemb_55A PF09788.9 KXG45357.1 - 3.2 6.8 6.5 3.6 6.6 0.2 2.4 2 1 1 3 3 3 0 Transmembrane protein 55A DUF2569 PF10754.9 KXG45357.1 - 4.9 7.6 10.4 2.5 8.5 4.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2569) PRA1 PF03208.19 KXG45359.1 - 3e-37 127.4 1.0 3.6e-37 127.1 1.0 1.1 1 0 0 1 1 1 1 PRA1 family protein DnaJ PF00226.31 KXG45360.1 - 1.8e-09 37.6 0.4 5.9e-09 35.9 0.4 1.9 1 0 0 1 1 1 1 DnaJ domain Ada3 PF10198.9 KXG45360.1 - 8.1 6.6 8.8 2.5 8.2 0.8 2.4 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 DnaJ PF00226.31 KXG45362.1 - 3.8e-21 75.0 1.3 5.9e-21 74.4 1.3 1.3 1 0 0 1 1 1 1 DnaJ domain Gly-zipper_Omp PF13488.6 KXG45362.1 - 0.19 11.7 12.5 0.35 10.9 12.5 1.4 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_OmpA PF13436.6 KXG45362.1 - 0.21 11.4 9.5 0.38 10.6 9.5 1.4 1 0 0 1 1 1 0 Glycine-zipper domain Bacteriocin_IIc PF10439.9 KXG45362.1 - 0.3 11.2 9.0 0.52 10.5 9.0 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.6 KXG45362.1 - 0.49 10.2 13.8 2.1 8.1 2.2 2.1 1 1 1 2 2 2 0 YMGG-like Gly-zipper PT-VENN PF04829.13 KXG45362.1 - 4.3 7.5 5.2 8.9 6.5 5.2 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Rick_17kDa_Anti PF05433.15 KXG45362.1 - 7.2 6.6 15.8 1.8 8.5 5.4 2.0 1 1 1 2 2 2 0 Glycine zipper 2TM domain PMM PF03332.13 KXG45363.1 - 7.9e-102 339.7 0.2 9.3e-102 339.5 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KXG45363.1 - 0.0017 18.2 0.0 0.0064 16.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KXG45363.1 - 0.0063 16.1 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase TMPIT PF07851.13 KXG45363.1 - 0.028 13.7 0.0 0.038 13.2 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1640 PF07798.11 KXG45364.1 - 1.6e-43 148.7 5.9 1.5e-31 109.8 1.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1640) DUF2175 PF09943.9 KXG45364.1 - 1.9 8.8 5.4 0.6 10.4 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Pilin_GH PF16734.5 KXG45365.1 - 0.097 13.0 0.2 9.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Type IV pilin-like G and H, putative DUF4131 PF13567.6 KXG45365.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PNGaseA PF12222.8 KXG45366.1 - 1.8e-185 616.9 0.2 2.4e-185 616.5 0.2 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A BTB PF00651.31 KXG45366.1 - 1.5e-09 38.0 0.3 3.5e-09 36.9 0.3 1.6 1 0 0 1 1 1 1 BTB/POZ domain Prok-RING_4 PF14447.6 KXG45366.1 - 0.11 12.4 0.8 0.26 11.2 0.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 SNF2_N PF00176.23 KXG45367.1 - 4.5e-58 196.6 0.0 9.2e-58 195.6 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 KXG45367.1 - 3.4e-08 33.2 9.7 1.1e-07 31.6 9.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXG45367.1 - 6.1e-08 32.4 8.9 1.7e-07 31.0 8.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXG45367.1 - 9.2e-08 31.8 8.5 2.3e-07 30.5 8.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXG45367.1 - 7.7e-07 29.3 10.4 2e-06 28.0 10.4 1.8 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KXG45367.1 - 3.6e-06 26.7 7.7 8.5e-06 25.5 7.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 ResIII PF04851.15 KXG45367.1 - 2.8e-05 24.2 0.1 0.005 16.8 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 KXG45367.1 - 0.00045 20.2 6.9 0.0014 18.6 6.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KXG45367.1 - 0.00058 20.1 8.5 0.0016 18.6 8.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXG45367.1 - 0.0022 17.9 8.8 0.0022 17.9 8.8 1.8 2 0 0 2 2 1 1 zinc-RING finger domain TPR_2 PF07719.17 KXG45367.1 - 0.027 14.6 2.6 0.036 14.2 0.8 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat Helicase_C PF00271.31 KXG45367.1 - 0.031 14.6 0.0 0.08 13.3 0.0 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.6 KXG45367.1 - 0.041 14.0 8.4 0.1 12.8 8.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 KXG45367.1 - 0.073 13.0 2.3 0.1 12.5 0.5 2.2 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) TPR_1 PF00515.28 KXG45367.1 - 0.091 12.6 0.8 0.46 10.4 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXG45367.1 - 0.12 12.7 0.7 0.45 10.8 0.7 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 KXG45367.1 - 1.1 9.1 6.0 3.2 7.6 6.0 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ecm29 PF13001.7 KXG45368.1 - 3.5e-163 543.9 0.0 2.5e-161 537.8 0.0 2.8 3 0 0 3 3 3 2 Proteasome stabiliser HEAT_EZ PF13513.6 KXG45368.1 - 9e-07 29.3 9.4 0.3 11.6 0.0 8.2 9 1 1 10 10 10 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KXG45368.1 - 1.1e-05 25.9 0.2 0.02 15.5 0.1 5.2 6 2 2 8 8 8 1 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KXG45368.1 - 0.0044 16.2 2.6 0.14 11.2 0.2 3.9 4 1 0 4 4 4 1 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 KXG45368.1 - 0.012 15.8 8.0 5.7 7.5 0.1 6.7 7 0 0 7 7 7 0 HEAT repeat Fungal_trans_2 PF11951.8 KXG45369.1 - 1.1e-13 50.8 3.6 1.7e-13 50.2 3.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain WW PF00397.26 KXG45369.1 - 2.6e-11 43.4 0.4 5.9e-11 42.3 0.4 1.7 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 KXG45369.1 - 0.052 12.6 0.1 0.1 11.6 0.1 1.4 1 0 0 1 1 1 0 PhoD-like phosphatase Lipase_3 PF01764.25 KXG45370.1 - 1e-17 64.3 0.0 1.8e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) WD40 PF00400.32 KXG45370.1 - 3e-14 53.2 6.8 0.00042 21.1 0.0 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG45370.1 - 1.4e-05 25.3 0.0 0.059 13.7 0.0 4.1 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 KXG45371.1 - 1.6e-08 34.2 0.0 2.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXG45371.1 - 9.1e-06 25.3 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 KXG45371.1 - 0.088 12.5 1.1 0.25 11.1 0.0 2.1 2 1 1 3 3 3 0 Calcipressin HSP20 PF00011.21 KXG45373.1 - 2.3e-17 63.0 0.0 4.7e-12 45.9 0.0 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXG45373.1 - 0.00033 20.2 0.0 0.0037 16.8 0.0 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Peptidase_M36 PF02128.15 KXG45373.1 - 0.011 14.9 0.4 0.015 14.5 0.4 1.1 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) Pap_E4 PF02711.14 KXG45373.1 - 1.4 10.0 4.5 7.6 7.6 3.8 2.3 1 1 0 1 1 1 0 E4 protein FAA_hydrolase PF01557.18 KXG45374.1 - 5.1e-66 222.5 0.0 6.4e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 KXG45374.1 - 0.053 13.9 0.2 0.092 13.2 0.2 1.3 1 0 0 1 1 1 0 Type II transport protein GspH Proteasome PF00227.26 KXG45375.1 - 2.1e-27 95.8 0.0 2.6e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Glyco_hydro_4 PF02056.16 KXG45375.1 - 0.045 13.3 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase HCNGP PF07818.13 KXG45377.1 - 9.7e-31 106.3 0.6 1.6e-30 105.6 0.6 1.3 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.26 KXG45378.1 - 2.9e-32 111.7 0.9 5.8e-31 107.5 0.9 2.1 1 1 0 1 1 1 1 Proteasome subunit KH_8 PF17903.1 KXG45379.1 - 0.00011 22.2 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KXG45379.1 - 0.004 16.9 1.0 0.0089 15.8 1.0 1.6 1 0 0 1 1 1 1 KH domain MDM31_MDM32 PF08118.11 KXG45380.1 - 5.8e-252 837.0 0.3 1e-251 836.2 0.3 1.4 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins RhoGAP PF00620.27 KXG45381.1 - 6.2e-42 143.0 0.1 1.2e-41 142.1 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KXG45381.1 - 7.5e-15 55.3 0.0 1.5e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KXG45381.1 - 0.00012 22.5 0.0 0.00042 20.7 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KXG45381.1 - 0.027 14.7 0.0 0.34 11.2 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3450 PF11932.8 KXG45381.1 - 0.23 10.7 1.7 0.48 9.7 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Erv26 PF04148.13 KXG45382.1 - 5.7e-93 310.4 0.0 6.4e-93 310.3 0.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 COX1 PF00115.20 KXG45382.1 - 0.013 14.3 3.7 0.017 14.0 3.7 1.0 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I WBS_methylT PF12589.8 KXG45383.1 - 3e-14 53.5 0.7 5.3e-14 52.7 0.7 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KXG45383.1 - 4.5e-11 43.2 0.0 8.4e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG45383.1 - 9.5e-11 42.3 0.0 2.6e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG45383.1 - 1.8e-05 25.4 0.0 4.4e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG45383.1 - 0.0001 22.1 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXG45383.1 - 0.00095 19.0 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KXG45383.1 - 0.0081 15.5 0.0 0.027 13.8 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXG45383.1 - 0.0094 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXG45383.1 - 0.15 11.4 0.0 1.5 8.1 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Iso_dh PF00180.20 KXG45384.1 - 5e-85 285.7 0.0 6e-85 285.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HTH_1 PF00126.27 KXG45385.1 - 0.19 11.7 2.7 2 8.5 0.2 2.3 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family ATP-synt_DE PF00401.20 KXG45385.1 - 0.96 9.8 10.4 1.1 9.5 0.6 2.3 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Proteasome PF00227.26 KXG45387.1 - 3.4e-46 157.1 0.6 7e-33 113.7 0.0 2.3 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.9 KXG45387.1 - 5.4e-12 45.2 1.0 6.3e-12 44.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DMRL_synthase PF00885.19 KXG45388.1 - 2.6e-58 195.9 0.1 3.1e-58 195.6 0.1 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF2108 PF09881.9 KXG45388.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2108) SIS PF01380.22 KXG45389.1 - 1.3e-57 193.3 0.0 1.2e-30 106.0 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KXG45389.1 - 1.5e-17 64.1 0.0 2.8e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KXG45389.1 - 7.3e-11 42.0 0.0 1.6e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KXG45389.1 - 0.00018 20.5 0.0 0.00029 19.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 KXG45389.1 - 0.091 11.4 0.0 0.33 9.6 0.0 1.7 2 0 0 2 2 2 0 Glutamine amidotransferases class-II N-SET PF11764.8 KXG45390.1 - 3.5e-56 190.0 2.0 3.5e-56 190.0 2.0 2.0 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KXG45390.1 - 5e-26 90.1 0.7 1.4e-25 88.7 0.7 1.8 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 KXG45390.1 - 1.1e-19 71.5 0.2 1.1e-19 71.5 0.2 3.4 2 1 0 2 2 2 1 SET domain RRM_1 PF00076.22 KXG45390.1 - 0.00054 19.7 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trm112p PF03966.16 KXG45391.1 - 1.2e-15 57.8 0.1 1.4e-15 57.6 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein CBX7_C PF17218.3 KXG45391.1 - 0.1 12.4 1.8 0.19 11.5 1.8 1.5 1 0 0 1 1 1 0 CBX family C-terminal motif Zn_ribbon_recom PF13408.6 KXG45391.1 - 0.1 13.1 0.6 0.19 12.3 0.6 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Rad60-SLD PF11976.8 KXG45392.1 - 1.6e-21 75.9 0.3 5.1e-18 64.7 0.9 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXG45392.1 - 0.00037 20.2 0.0 0.015 15.0 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family LSM PF01423.22 KXG45393.1 - 7.4e-17 60.8 0.1 9.1e-17 60.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXG45393.1 - 0.0014 18.8 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KXG45393.1 - 0.048 13.8 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Hfq PF17209.3 KXG45393.1 - 0.11 12.1 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Hfq protein IF-2B PF01008.17 KXG45394.1 - 1.4e-72 244.3 3.2 1.6e-72 244.1 3.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Fcf1 PF04900.12 KXG45395.1 - 1.2e-36 125.0 0.2 2.5e-36 124.0 0.2 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KXG45395.1 - 4.1e-11 43.2 0.6 6e-11 42.7 0.0 1.5 2 0 0 2 2 2 1 PIN like domain DUF3987 PF13148.6 KXG45395.1 - 0.18 10.7 1.4 0.25 10.3 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) XPG_I_2 PF12813.7 KXG45396.1 - 1.7e-83 279.9 0.0 2.8e-83 279.2 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing Utp21 PF04192.12 KXG45396.1 - 2.3e-69 233.4 0.1 5.3e-67 225.7 0.1 2.3 1 1 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 KXG45396.1 - 3.1e-14 53.0 0.0 0.037 14.3 0.0 6.6 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXG45396.1 - 6.6e-09 36.3 27.3 8.5e-05 23.3 0.4 9.2 10 0 0 10 10 10 3 WD domain, G-beta repeat XPG_I PF00867.18 KXG45396.1 - 0.079 13.3 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 XPG I-region Cytochrom_D1 PF02239.16 KXG45396.1 - 0.14 10.7 0.0 0.44 9.0 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain His_Phos_2 PF00328.22 KXG45397.1 - 2.8e-112 375.8 0.1 3.9e-112 375.4 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KXG45397.1 - 4.4e-37 126.1 0.0 1.2e-36 124.8 0.0 1.8 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KXG45397.1 - 3.9e-05 23.3 0.0 8.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DAGK_cat PF00781.24 KXG45398.1 - 1.5e-12 47.2 0.0 2.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ABC_tran PF00005.27 KXG45399.1 - 2.1e-43 148.1 0.1 4.6e-23 82.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter DUF676 PF05057.14 KXG45399.1 - 4e-40 137.6 0.1 1.2e-26 93.6 0.0 3.3 3 0 0 3 3 3 3 Putative serine esterase (DUF676) ABC_membrane PF00664.23 KXG45399.1 - 2.2e-26 93.1 23.5 9.1e-26 91.1 12.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KXG45399.1 - 2.5e-08 33.6 3.9 0.032 13.7 0.0 4.2 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXG45399.1 - 1.1e-07 32.0 2.5 0.39 10.5 0.2 4.5 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXG45399.1 - 2.3e-05 24.7 1.9 0.028 14.7 0.2 3.0 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 KXG45399.1 - 3.7e-05 22.9 0.5 0.042 12.9 0.2 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KXG45399.1 - 0.00022 20.9 1.8 0.55 10.0 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 KXG45399.1 - 0.00028 21.1 0.0 0.0045 17.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXG45399.1 - 0.00037 20.9 0.2 0.062 13.7 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXG45399.1 - 0.0007 19.5 0.1 0.21 11.5 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 KXG45399.1 - 0.0021 18.2 0.0 0.46 10.8 0.0 3.1 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KXG45399.1 - 0.0043 17.6 0.4 0.59 10.7 0.1 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KXG45399.1 - 0.0094 16.0 0.4 2.3 8.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 KXG45399.1 - 0.012 16.0 0.3 0.15 12.5 0.1 2.5 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KXG45399.1 - 0.016 15.2 0.1 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 KXG45399.1 - 0.026 15.0 1.0 4.6 7.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXG45399.1 - 0.026 14.0 0.2 2.9 7.4 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 KXG45399.1 - 0.033 13.8 2.8 0.064 12.8 0.6 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KXG45399.1 - 0.052 13.5 1.0 8.7 6.3 0.1 3.7 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Lipase_3 PF01764.25 KXG45399.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) RNA_helicase PF00910.22 KXG45399.1 - 0.057 13.8 0.2 5.4 7.4 0.0 3.1 3 0 0 3 3 3 0 RNA helicase IstB_IS21 PF01695.17 KXG45399.1 - 0.084 12.6 0.0 16 5.2 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF915 PF06028.11 KXG45399.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Zeta_toxin PF06414.12 KXG45399.1 - 0.14 11.4 0.3 11 5.3 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KXG45399.1 - 0.15 11.3 1.3 9.4 5.5 0.0 2.6 3 0 0 3 3 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.9 KXG45399.1 - 0.18 11.5 0.6 1.9 8.2 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KXG45399.1 - 0.24 11.3 1.6 0.56 10.1 0.3 2.2 2 0 0 2 2 2 0 NACHT domain Inositol_P PF00459.25 KXG45400.1 - 3.1e-65 220.4 0.0 3.7e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family OPT PF03169.15 KXG45401.1 - 2.5e-166 554.9 27.9 2.9e-117 392.9 12.1 2.1 1 1 1 2 2 2 2 OPT oligopeptide transporter protein DUF383 PF04063.14 KXG45401.1 - 2.3e-67 226.4 0.1 5.6e-67 225.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KXG45401.1 - 8.5e-23 80.0 1.7 2.8e-22 78.3 1.7 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF384) TFIIF_alpha PF05793.12 KXG45401.1 - 4.5e-11 42.1 50.8 1.2e-08 34.0 3.3 3.1 1 1 1 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAS_I_H PF18314.1 KXG45402.1 - 2.8e-78 262.2 0.0 2.8e-78 262.2 0.0 2.2 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KXG45402.1 - 1.7e-73 246.3 0.0 3.9e-73 245.1 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KXG45402.1 - 6.9e-22 78.2 0.1 1.5e-21 77.2 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KXG45402.1 - 5.4e-17 62.0 0.0 1.4e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KXG45402.1 - 9.3e-12 45.0 0.6 2.6e-11 43.6 0.0 2.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 KXG45402.1 - 0.0005 20.0 0.0 0.002 18.1 0.0 2.0 1 0 0 1 1 1 1 KR domain DarA_N PF18788.1 KXG45402.1 - 0.16 12.1 0.8 0.83 9.8 0.1 2.4 2 0 0 2 2 2 0 Defence against restriction A N-terminal 4PPT_N PF17837.1 KXG45402.1 - 1 9.5 2.6 9.4 6.4 2.6 2.3 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain DUF1729 PF08354.10 KXG45403.1 - 3.6e-161 536.0 0.0 5.7e-161 535.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KXG45403.1 - 4.3e-91 305.7 0.0 3.6e-89 299.4 0.0 3.3 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 KXG45403.1 - 6.1e-53 178.6 0.0 2.2e-52 176.7 0.0 2.0 2 0 0 2 2 2 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 KXG45403.1 - 8.1e-43 145.5 0.0 1.9e-42 144.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta SAT PF16073.5 KXG45403.1 - 1.3e-39 136.4 0.1 4.4e-39 134.6 0.0 2.0 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 KXG45403.1 - 1.5e-38 131.1 0.0 3.6e-38 129.9 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KXG45403.1 - 7.3e-22 77.9 0.0 2.5e-21 76.2 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.15 KXG45403.1 - 0.037 13.4 0.3 0.29 10.5 0.3 2.2 1 1 0 1 1 1 0 Nitronate monooxygenase TRM PF02005.16 KXG45404.1 - 8.8e-117 390.4 0.0 4.9e-99 332.1 0.0 2.1 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase DUF2067 PF09840.9 KXG45404.1 - 0.00015 21.4 0.0 0.00035 20.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2067) Met_10 PF02475.16 KXG45404.1 - 0.00033 20.4 0.0 0.00058 19.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 KXG45404.1 - 0.016 15.9 0.0 0.036 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXG45404.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KXG45404.1 - 0.15 11.4 0.1 0.29 10.5 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXG45404.1 - 0.17 11.4 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain UPF0561 PF10573.9 KXG45404.1 - 0.25 11.5 2.9 0.59 10.3 2.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Trypan_PARP PF05887.11 KXG45404.1 - 2.1 8.3 9.9 0.31 11.0 3.3 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) CCDC53 PF10152.9 KXG45404.1 - 4.6 7.6 14.3 4.7 7.6 2.8 3.1 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex SKA1 PF07160.12 KXG45404.1 - 6 6.6 7.2 1.3 8.9 0.2 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF1691 PF07950.11 KXG45405.1 - 1.2e-40 138.5 7.8 1.4e-33 115.8 4.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) zf-C2H2 PF00096.26 KXG45406.1 - 0.0028 18.0 1.2 0.0069 16.8 1.2 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.7 KXG45406.1 - 0.0046 17.3 0.3 0.01 16.2 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXG45406.1 - 0.028 14.7 1.9 0.028 14.7 1.9 1.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXG45406.1 - 0.066 13.6 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 KXG45406.1 - 0.071 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 KXG45406.1 - 0.081 13.8 0.5 0.21 12.5 0.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Transket_pyr PF02779.24 KXG45407.1 - 3.4e-45 153.9 0.0 5.4e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXG45407.1 - 1.9e-36 124.7 0.1 4e-35 120.4 0.0 2.4 2 0 0 2 2 2 1 Transketolase, C-terminal domain Metallophos PF00149.28 KXG45408.1 - 1.5e-05 25.6 0.2 3.3e-05 24.5 0.2 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ADH_zinc_N PF00107.26 KXG45409.1 - 8.4e-14 51.7 0.0 1.4e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4265 PF14085.6 KXG45409.1 - 0.047 13.7 0.0 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) ADH_N PF08240.12 KXG45409.1 - 0.095 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Amidase PF01425.21 KXG45410.1 - 5.3e-118 394.8 0.7 6.3e-118 394.6 0.7 1.0 1 0 0 1 1 1 1 Amidase Bystin PF05291.11 KXG45412.1 - 6.7e-129 429.3 0.0 8.6e-129 429.0 0.0 1.1 1 0 0 1 1 1 1 Bystin Toprim_C_rpt PF13368.6 KXG45412.1 - 0.026 14.5 0.1 0.072 13.1 0.1 1.7 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat bZIP_2 PF07716.15 KXG45413.1 - 9.9e-12 44.8 15.4 9.9e-12 44.8 15.4 2.3 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 KXG45413.1 - 2.7e-07 30.6 16.7 4.6e-07 29.8 16.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KXG45413.1 - 0.00037 21.0 13.7 0.00071 20.0 13.7 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor FPP PF05911.11 KXG45413.1 - 0.002 16.4 5.9 0.0023 16.2 5.9 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Rootletin PF15035.6 KXG45413.1 - 0.0073 16.3 8.0 0.0099 15.9 8.0 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion CENP-H PF05837.12 KXG45413.1 - 1 9.8 10.6 2.2 8.7 10.6 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) APG6_N PF17675.1 KXG45413.1 - 3.1 8.3 16.4 0.24 11.9 11.8 1.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Snf7 PF03357.21 KXG45414.1 - 0.036 13.7 7.6 0.05 13.2 7.6 1.2 1 0 0 1 1 1 0 Snf7 PqqD PF05402.12 KXG45414.1 - 0.13 12.5 0.0 9.5 6.6 0.1 2.6 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) DUF2207 PF09972.9 KXG45415.1 - 0.0022 16.8 0.3 0.0022 16.8 0.3 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) ABC2_membrane_3 PF12698.7 KXG45415.1 - 3.3 6.7 7.3 9.1 5.3 7.3 1.7 1 0 0 1 1 1 0 ABC-2 family transporter protein CoA_trans PF01144.23 KXG45419.1 - 5.2e-98 326.8 1.5 1.4e-60 204.4 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KXG45419.1 - 0.0064 16.4 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain MFS_1 PF07690.16 KXG45420.1 - 7.4e-38 130.4 24.8 7.4e-38 130.4 24.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXG45420.1 - 0.00012 21.9 0.7 0.00026 20.7 0.7 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DALR_2 PF09190.11 KXG45421.1 - 0.19 12.3 0.0 19 5.8 0.0 2.5 2 0 0 2 2 2 0 DALR domain UvrD-helicase PF00580.21 KXG45422.1 - 2.5e-62 211.2 2.4 1e-60 205.9 0.2 2.9 3 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KXG45422.1 - 2.7e-57 194.8 0.1 7.7e-56 189.9 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KXG45422.1 - 4e-31 108.3 0.0 1.1e-30 107.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KXG45422.1 - 1.3e-14 53.8 0.1 3e-14 52.6 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KXG45422.1 - 1.2e-08 34.9 0.1 0.00021 21.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 KXG45422.1 - 6.2e-06 26.0 0.0 0.00021 21.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KXG45422.1 - 0.00036 20.4 0.5 0.18 11.5 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KXG45422.1 - 0.00083 19.6 0.9 0.19 12.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_11 PF13086.6 KXG45422.1 - 0.0017 18.2 0.2 0.0088 15.9 0.0 2.2 3 0 0 3 3 3 1 AAA domain Rrp15p PF07890.12 KXG45422.1 - 0.0094 16.3 0.2 0.03 14.6 0.1 1.9 2 0 0 2 2 2 1 Rrp15p SnoaL_4 PF13577.6 KXG45423.1 - 3.9e-20 72.3 0.1 5e-20 71.9 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXG45423.1 - 0.062 13.7 0.2 0.12 12.8 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) FmdA_AmdA PF03069.15 KXG45424.1 - 9.5e-55 186.0 0.0 4.1e-32 111.5 0.0 2.1 1 1 1 2 2 2 2 Acetamidase/Formamidase family PP2C PF00481.21 KXG45425.1 - 8.2e-41 140.3 0.0 9.6e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KXG45425.1 - 4.2e-08 33.1 0.1 1.4e-05 24.8 0.0 2.5 2 1 1 3 3 3 2 Protein phosphatase 2C SpoIIE PF07228.12 KXG45425.1 - 3.7e-05 23.7 0.3 0.32 10.9 0.1 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Cyt-b5 PF00173.28 KXG45426.1 - 2e-14 53.5 0.0 2.8e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FKBP_C PF00254.28 KXG45427.1 - 8e-33 112.6 0.0 9.5e-33 112.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Sugar_tr PF00083.24 KXG45428.1 - 1.4e-53 182.4 23.3 2e-52 178.6 23.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG45428.1 - 3.8e-14 52.4 37.7 1.7e-07 30.5 15.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Zip PF02535.22 KXG45429.1 - 3.1e-65 220.6 9.3 3.6e-65 220.4 9.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Cation_ATPase_C PF00689.21 KXG45429.1 - 0.22 11.2 10.0 0.43 10.3 1.5 2.6 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus PRP9_N PF16958.5 KXG45430.1 - 0.076 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus KI67R PF08065.12 KXG45430.1 - 0.13 12.8 1.4 0.31 11.6 1.4 1.7 1 1 0 1 1 1 0 KI67R (NUC007) repeat Tom37 PF10568.9 KXG45431.1 - 8.4e-40 136.0 0.2 1.6e-39 135.1 0.2 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KXG45431.1 - 1.3e-06 29.1 0.1 3.3e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KXG45431.1 - 2e-06 27.5 0.1 7e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain PEP_mutase PF13714.6 KXG45433.1 - 2.6e-46 158.0 0.5 3e-46 157.8 0.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KXG45433.1 - 6.4e-19 67.8 0.1 9e-19 67.3 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Hist_deacetyl PF00850.19 KXG45434.1 - 1.1e-76 258.2 0.1 1.6e-76 257.7 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Oxysterol_BP PF01237.18 KXG45435.1 - 8.5e-92 307.9 0.0 2.6e-89 299.6 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF4996 PF16387.5 KXG45435.1 - 0.099 13.1 0.2 0.21 12.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF3605 PF12239.8 KXG45436.1 - 1.3e-56 191.1 0.7 1.7e-56 190.8 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Isochorismatase PF00857.20 KXG45437.1 - 2.1e-26 93.2 0.0 4.8e-26 92.0 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family DUF1131 PF06572.12 KXG45437.1 - 0.098 12.4 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) Ssu72 PF04722.13 KXG45438.1 - 1.2e-80 269.6 0.0 1.4e-80 269.3 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Mito_fiss_reg PF05308.11 KXG45438.1 - 1.3 9.1 2.9 1.9 8.5 2.9 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 KXG45438.1 - 2.4 8.2 6.4 4.2 7.4 6.4 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Dscam_C PF12355.8 KXG45438.1 - 3 8.8 6.9 0.59 11.1 2.9 2.0 3 0 0 3 3 3 0 Down syndrome cell adhesion molecule C terminal CAP_N PF01213.19 KXG45438.1 - 3.9 6.9 9.2 5.8 6.3 9.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SNF2_N PF00176.23 KXG45439.1 - 1.7e-49 168.5 0.0 2.6e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 KXG45439.1 - 8.7e-28 96.2 0.1 2.4e-27 94.8 0.1 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 KXG45439.1 - 4.2e-21 75.4 0.0 6.8e-19 68.2 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG45439.1 - 8.5e-09 35.6 0.0 2.7e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXG45439.1 - 3.2e-06 26.5 0.0 6.2e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Ctr PF04145.15 KXG45440.1 - 5.6e-41 140.6 0.1 9.2e-41 139.9 0.1 1.4 1 0 0 1 1 1 1 Ctr copper transporter family RNase_PH PF01138.21 KXG45440.1 - 8.1e-31 107.3 0.7 1.3e-30 106.6 0.2 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Oxidored_q3 PF00499.20 KXG45440.1 - 1.4 8.6 9.0 6.4 6.5 9.4 1.8 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Pro_isomerase PF00160.21 KXG45441.1 - 2.7e-42 144.7 0.2 9.7e-42 142.9 0.2 1.9 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GIT_SHD PF08518.11 KXG45441.1 - 1.8e-23 81.8 8.8 2.3e-14 52.7 0.5 3.1 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 KXG45441.1 - 4.2e-05 23.6 0.8 4.2e-05 23.6 0.8 2.3 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term BRE1 PF08647.11 KXG45441.1 - 1.4 9.1 21.3 0.12 12.5 4.6 3.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 KXG45441.1 - 7.4 7.1 34.9 0.067 13.7 20.8 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region HMG-CoA_red PF00368.18 KXG45442.1 - 1.4e-137 458.6 5.8 1.8e-137 458.3 5.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KXG45442.1 - 8.9e-51 171.8 0.2 1.6e-50 171.0 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KXG45442.1 - 2.2e-13 50.3 2.0 1.3e-12 47.8 2.0 2.3 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KXG45442.1 - 1.2e-06 26.9 1.1 1.2e-06 26.9 1.1 1.4 2 0 0 2 2 2 1 Patched family SH3_1 PF00018.28 KXG45444.1 - 1e-10 41.1 0.0 2e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXG45444.1 - 2.6e-09 36.8 0.1 4.9e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXG45444.1 - 1.1e-07 31.4 0.0 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF1180 PF06679.12 KXG45444.1 - 3.3 8.1 6.2 7.2 7.0 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) ENTH PF01417.20 KXG45445.1 - 6.4e-45 152.2 0.2 1e-44 151.6 0.2 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KXG45445.1 - 0.0014 17.6 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 ANTH domain RasGAP_C PF03836.15 KXG45446.1 - 2.6e-46 157.2 2.8 2.6e-46 157.2 2.8 3.0 2 1 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.19 KXG45446.1 - 6e-46 156.8 0.2 1.8e-45 155.2 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 KXG45446.1 - 3.3e-11 43.3 0.0 1.1e-10 41.6 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 KXG45446.1 - 6.4e-08 31.7 60.7 0.88 9.5 0.1 14.8 16 0 0 16 16 16 9 IQ calmodulin-binding motif Trypan_PARP PF05887.11 KXG45446.1 - 0.041 13.9 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF952 PF06108.12 KXG45447.1 - 7.5e-20 70.7 0.0 9.7e-20 70.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) adh_short_C2 PF13561.6 KXG45448.1 - 3.9e-51 173.9 0.0 5.4e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG45448.1 - 1.3e-45 155.3 0.1 1.5e-45 155.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG45448.1 - 6.8e-11 42.4 0.1 1e-10 41.9 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXG45448.1 - 0.015 14.7 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXG45448.1 - 0.029 13.8 0.0 0.05 13.0 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ATP_bind_2 PF03668.15 KXG45448.1 - 0.1 11.9 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 P-loop ATPase protein family THF_DHG_CYH_C PF02882.19 KXG45448.1 - 0.11 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain IMPDH PF00478.25 KXG45449.1 - 4.8e-127 423.7 6.2 6.3e-127 423.3 6.2 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Ribosomal_S21e PF01249.18 KXG45449.1 - 7.6e-40 134.9 0.0 2.5e-39 133.2 0.0 2.0 1 0 0 1 1 1 1 Ribosomal protein S21e CBS PF00571.28 KXG45449.1 - 1.6e-16 60.5 0.0 3.6e-08 33.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 KXG45449.1 - 1.5e-05 24.2 1.2 3.3e-05 23.1 0.6 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KXG45449.1 - 3.4e-05 23.4 3.4 0.0055 16.1 1.7 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase NUDIX PF00293.28 KXG45449.1 - 3.6e-05 23.8 0.0 9.2e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain His_biosynth PF00977.21 KXG45449.1 - 0.0028 17.1 3.4 0.036 13.5 0.3 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein PK PF00224.21 KXG45449.1 - 0.058 12.3 0.0 0.15 10.9 0.0 1.5 1 1 0 1 1 1 0 Pyruvate kinase, barrel domain Aldolase PF01081.19 KXG45449.1 - 0.076 12.4 0.7 0.23 10.9 0.1 2.0 2 0 0 2 2 2 0 KDPG and KHG aldolase YpsA PF06908.11 KXG45449.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family tRNA-synt_2d PF01409.20 KXG45450.1 - 4.5e-87 291.6 0.0 7e-87 291.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KXG45450.1 - 2.1e-15 56.7 0.3 5.9e-15 55.3 0.3 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KXG45450.1 - 2.5e-08 33.6 0.0 0.00031 20.2 0.0 2.4 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KXG45450.1 - 0.00078 18.6 0.1 0.014 14.5 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 KXG45450.1 - 0.075 13.0 6.4 0.29 11.2 6.4 2.1 1 0 0 1 1 1 0 PheRS DNA binding domain 2 Androgen_recep PF02166.16 KXG45450.1 - 0.084 11.7 0.5 0.13 11.0 0.5 1.2 1 0 0 1 1 1 0 Androgen receptor HAMP PF00672.25 KXG45451.1 - 8.9e-44 147.7 14.2 1.3e-08 35.0 0.4 7.4 6 1 0 6 6 6 5 HAMP domain HATPase_c PF02518.26 KXG45451.1 - 9.1e-33 113.1 0.2 3.5e-32 111.2 0.2 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXG45451.1 - 3.8e-26 91.5 0.6 1.9e-25 89.2 0.6 2.3 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXG45451.1 - 7.4e-17 61.1 3.3 3.1e-16 59.2 0.2 3.7 4 0 0 4 4 3 1 His Kinase A (phospho-acceptor) domain APG17 PF04108.12 KXG45451.1 - 1.9e-14 53.6 7.1 0.011 14.9 0.0 5.9 1 1 2 4 4 4 3 Autophagy protein Apg17 Syntaxin_2 PF14523.6 KXG45451.1 - 3.1e-06 27.5 20.6 1.1 9.6 0.1 7.3 3 2 2 6 6 6 2 Syntaxin-like protein DUF4279 PF14106.6 KXG45451.1 - 0.00032 20.9 0.7 7.8 6.7 0.0 5.6 6 1 0 6 6 6 0 Domain of unknown function (DUF4279) DUF1843 PF08898.10 KXG45451.1 - 0.00095 19.6 7.1 16 6.1 0.1 6.1 5 1 0 5 5 5 0 Domain of unknown function (DUF1843) DUF948 PF06103.11 KXG45451.1 - 0.0041 17.3 57.3 1.1 9.6 0.2 10.2 4 2 2 6 6 5 1 Bacterial protein of unknown function (DUF948) Gp-FAR-1 PF05823.12 KXG45451.1 - 0.012 16.0 5.7 21 5.5 0.1 5.0 1 1 3 5 5 5 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SpoIIID PF12116.8 KXG45451.1 - 0.031 14.3 4.8 23 5.1 0.0 5.3 5 0 0 5 5 5 0 Stage III sporulation protein D Fib_alpha PF08702.10 KXG45451.1 - 0.038 14.2 34.2 1.1 9.4 0.6 7.3 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family NOD PF06816.13 KXG45451.1 - 0.045 13.4 0.0 6.4 6.5 0.0 2.8 2 0 0 2 2 2 0 NOTCH protein Cbl_N PF02262.16 KXG45451.1 - 0.068 13.2 0.1 3.8 7.5 0.1 2.9 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 IcmF_C PF06744.12 KXG45451.1 - 0.081 12.5 0.1 0.31 10.6 0.1 2.0 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal CMD PF02627.20 KXG45451.1 - 0.14 12.3 1.1 17 5.6 0.0 4.0 5 0 0 5 5 4 0 Carboxymuconolactone decarboxylase family DUF3829 PF12889.7 KXG45451.1 - 0.17 11.3 18.6 0.34 10.3 0.8 5.3 3 3 2 6 6 6 0 Protein of unknown function (DUF3829) DUF4795 PF16043.5 KXG45451.1 - 0.18 11.4 26.8 1.1 8.9 5.6 5.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) WXG100 PF06013.12 KXG45451.1 - 1.1 9.6 30.9 2 8.7 0.3 8.5 6 2 4 10 10 10 0 Proteins of 100 residues with WXG GLE1 PF07817.13 KXG45451.1 - 3.3 6.9 12.7 8.1 5.6 0.8 4.6 3 1 2 5 5 5 0 GLE1-like protein BORCS6 PF10157.9 KXG45451.1 - 5.3 7.2 18.6 6 7.1 0.1 6.0 4 2 2 6 6 6 0 BLOC-1-related complex sub-unit 6 APG6_N PF17675.1 KXG45451.1 - 5.5 7.5 12.1 52 4.4 7.1 4.0 3 0 0 3 3 3 0 Apg6 coiled-coil region Phage_Mu_Gam PF07352.12 KXG45451.1 - 5.6 6.8 17.5 6.8 6.6 0.2 5.6 5 1 1 6 6 6 0 Bacteriophage Mu Gam like protein Mer2 PF09074.10 KXG45451.1 - 5.8 6.7 37.4 3.3 7.5 2.9 6.0 3 1 3 6 6 6 0 Mer2 Ribosomal_L24e PF01246.20 KXG45452.1 - 3.6e-27 94.4 6.7 1e-26 92.9 6.7 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e Pam16 PF03656.13 KXG45453.1 - 3.2e-07 30.4 0.1 4.7e-07 29.9 0.1 1.4 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 KXG45453.1 - 9.2e-06 25.7 0.1 1.5e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.18 KXG45454.1 - 1e-24 87.0 0.1 3.4e-24 85.3 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG45454.1 - 8.5e-10 38.6 13.1 1.5e-09 37.9 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP11 PF06644.11 KXG45454.1 - 4.3 7.0 8.8 0.5 10.1 0.6 2.2 2 0 0 2 2 2 0 ATP11 protein Peptidase_M41 PF01434.18 KXG45455.1 - 6.7e-66 221.8 0.0 1.2e-65 221.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KXG45455.1 - 9.8e-43 145.8 0.0 3.4e-42 144.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXG45455.1 - 3.9e-12 45.8 0.1 9e-12 44.6 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KXG45455.1 - 1.2e-10 41.7 0.0 2.9e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 KXG45455.1 - 0.00065 19.7 0.0 0.0023 17.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) HpaB PF03241.13 KXG45455.1 - 0.0019 17.3 0.0 0.0041 16.2 0.0 1.5 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal AAA_16 PF13191.6 KXG45455.1 - 0.0033 17.8 0.0 0.21 11.9 0.1 2.9 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXG45455.1 - 0.0064 16.2 0.0 0.02 14.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KXG45455.1 - 0.0096 15.2 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KXG45455.1 - 0.0099 16.1 0.3 1.2 9.4 0.1 3.3 4 0 0 4 4 4 1 AAA domain AAA_2 PF07724.14 KXG45455.1 - 0.04 14.0 0.0 0.14 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RR_TM4-6 PF06459.12 KXG45455.1 - 0.12 12.2 9.1 0.23 11.2 9.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IstB_IS21 PF01695.17 KXG45455.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF913 PF06025.12 KXG45455.1 - 0.18 10.8 1.2 0.28 10.1 1.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 KXG45455.1 - 6.1 5.5 8.5 9.9 4.8 8.5 1.2 1 0 0 1 1 1 0 Presenilin DUF1295 PF06966.12 KXG45457.1 - 2.1e-39 135.5 8.5 2.7e-39 135.1 8.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KXG45457.1 - 0.49 10.9 0.0 0.49 10.9 0.0 2.5 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.20 KXG45458.1 - 1.4e-101 340.5 0.0 1.8e-101 340.2 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KXG45458.1 - 3.9e-18 65.6 0.0 1.6e-17 63.6 0.0 2.0 2 0 0 2 2 2 1 Toprim domain FtsL PF04999.13 KXG45459.1 - 0.052 13.6 0.2 15 5.7 0.0 2.5 2 0 0 2 2 2 0 Cell division protein FtsL TPR_12 PF13424.6 KXG45461.1 - 1.7e-16 60.2 1.9 8.7e-07 29.1 0.0 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXG45461.1 - 2.7e-13 49.3 1.4 0.00015 21.6 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXG45461.1 - 4.8e-11 41.9 5.1 0.016 15.2 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXG45461.1 - 2.5e-05 23.9 0.9 0.15 11.9 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXG45461.1 - 0.00038 20.5 0.4 3.3 8.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXG45461.1 - 0.0023 18.4 7.8 0.15 12.6 0.2 4.0 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXG45461.1 - 0.0058 17.4 3.5 56 4.9 0.0 5.7 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXG45461.1 - 0.0059 16.3 0.9 2.4 7.9 0.1 4.3 4 1 0 4 4 4 1 TPR repeat TPR_6 PF13174.6 KXG45461.1 - 0.0068 17.0 0.2 18 6.2 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat NB-ARC PF00931.22 KXG45461.1 - 0.013 14.7 0.0 0.031 13.5 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain TPR_MalT PF17874.1 KXG45461.1 - 0.056 12.8 0.0 0.14 11.5 0.0 1.5 1 1 0 1 1 1 0 MalT-like TPR region CAMSAP_CH PF11971.8 KXG45461.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain SNAP PF14938.6 KXG45461.1 - 0.12 11.8 0.0 0.94 8.8 0.0 2.3 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_4 PF07721.14 KXG45461.1 - 0.13 12.9 5.9 41 5.2 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXG45461.1 - 1.2 9.8 11.1 30 5.4 0.0 4.8 3 2 1 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 KXG45462.1 - 4.2e-40 137.8 54.6 4.5e-33 114.6 34.6 3.7 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG45462.1 - 4.1e-13 48.6 17.9 7.8e-13 47.7 18.0 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 KXG45462.1 - 0.0041 17.3 4.9 0.086 13.1 0.5 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2530) HCV_NS4a PF01006.20 KXG45462.1 - 1.1 9.0 4.1 3 7.7 4.1 1.7 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a NAD_binding_4 PF07993.12 KXG45463.1 - 2.7e-31 108.7 0.0 4.1e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXG45463.1 - 6.9e-29 100.7 0.0 1e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KXG45463.1 - 3.5e-17 62.7 0.0 1.2e-16 60.9 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG45463.1 - 9e-08 31.9 0.0 1.8e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXG45463.1 - 3.5e-06 26.2 0.0 6.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 KXG45463.1 - 0.012 16.0 0.0 0.036 14.4 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site Sacchrp_dh_NADP PF03435.18 KXG45463.1 - 0.039 14.2 0.0 0.08 13.2 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KXG45464.1 - 4.3e-16 59.2 0.0 7.7e-16 58.3 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG45464.1 - 1.3e-12 47.9 0.0 9.2e-12 45.2 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KXG45464.1 - 5e-06 26.6 0.1 9.9e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KXG45464.1 - 0.0008 19.8 0.1 0.0014 19.1 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KXG45464.1 - 0.066 12.7 0.0 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Adap_comp_sub PF00928.21 KXG45464.1 - 0.083 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Adaptor complexes medium subunit family Methyltransf_24 PF13578.6 KXG45465.1 - 2.8e-13 50.8 0.0 4.5e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KXG45465.1 - 3.3e-11 42.7 0.0 4.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase CmcI PF04989.12 KXG45465.1 - 0.0029 17.4 0.0 0.0055 16.4 0.0 1.5 1 1 0 1 1 1 1 Cephalosporin hydroxylase Lyase_aromatic PF00221.19 KXG45466.1 - 6.8e-118 394.3 2.9 8.5e-118 393.9 2.9 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase FAD_binding_3 PF01494.19 KXG45467.1 - 9.1e-86 288.2 0.0 1.2e-85 287.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXG45467.1 - 5.5e-38 130.6 0.0 1.1e-37 129.7 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KXG45467.1 - 2e-06 26.8 0.3 3.2e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KXG45467.1 - 1.2e-05 24.6 1.0 2.5e-05 23.5 0.7 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG45467.1 - 1.6e-05 24.3 0.2 0.00013 21.3 0.1 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG45467.1 - 0.0002 20.7 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KXG45467.1 - 0.00076 18.7 0.5 0.0011 18.1 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXG45467.1 - 0.00076 18.9 1.3 0.00087 18.7 0.5 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXG45467.1 - 0.0015 17.9 0.2 0.0023 17.2 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG45467.1 - 0.0031 17.7 0.1 0.0083 16.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXG45467.1 - 0.0055 16.3 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXG45467.1 - 0.0083 15.2 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KXG45467.1 - 0.013 14.3 0.1 0.023 13.6 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KXG45467.1 - 0.033 13.5 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.10 KXG45467.1 - 0.046 12.8 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase XdhC_C PF13478.6 KXG45467.1 - 0.059 13.9 0.0 0.27 11.7 0.0 2.1 1 1 0 1 1 1 0 XdhC Rossmann domain Glyco_hydro_7 PF00840.20 KXG45468.1 - 8.5e-208 690.4 13.5 9.6e-208 690.2 13.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 ANAPC4_WD40 PF12894.7 KXG45469.1 - 1.6e-05 25.1 0.0 0.12 12.7 0.0 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain YL1 PF05764.13 KXG45469.1 - 0.0021 18.2 1.0 0.0031 17.7 1.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein RAB3GAP2_N PF14655.6 KXG45469.1 - 0.037 13.3 0.1 6.8 5.8 0.0 2.7 3 1 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.32 KXG45469.1 - 0.74 10.8 6.8 6.2 7.9 0.1 4.7 5 1 0 5 5 5 0 WD domain, G-beta repeat TSGP1 PF07771.11 KXG45469.1 - 0.81 9.9 4.6 1.6 8.9 4.6 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 Trypan_PARP PF05887.11 KXG45469.1 - 1.6 8.7 3.5 3.7 7.5 3.5 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MgtE PF01769.16 KXG45470.1 - 0.031 14.7 0.8 0.031 14.7 0.8 2.4 1 1 1 2 2 2 0 Divalent cation transporter FAD_binding_4 PF01565.23 KXG45471.1 - 1.2e-21 76.9 5.6 1.2e-21 76.9 4.2 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXG45471.1 - 1.9e-09 37.4 0.2 4e-09 36.4 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KXG45471.1 - 0.096 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Fe-ADH PF00465.19 KXG45472.1 - 7.1e-78 262.0 1.0 8.2e-78 261.8 1.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KXG45472.1 - 8.6e-16 58.4 0.6 1.2e-15 57.9 0.6 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase IMS_C PF11799.8 KXG45472.1 - 0.025 15.3 0.0 0.86 10.3 0.0 2.3 1 1 1 2 2 2 0 impB/mucB/samB family C-terminal domain Diphthamide_syn PF01866.17 KXG45473.1 - 5.1e-87 292.1 0.0 7.1e-87 291.7 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein CS PF04969.16 KXG45475.1 - 5.5e-17 62.6 0.0 9.6e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 CS domain Zn_clus PF00172.18 KXG45476.1 - 5.2e-10 39.3 10.7 9.5e-10 38.4 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXG45476.1 - 0.0018 17.2 0.1 0.0026 16.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAM70 PF14967.6 KXG45477.1 - 4.6 6.6 6.5 5.9 6.3 6.5 1.1 1 0 0 1 1 1 0 FAM70 protein Methyltransf_12 PF08242.12 KXG45478.1 - 6.6e-15 55.7 0.0 2.2e-14 54.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG45478.1 - 2.4e-13 50.6 0.0 7.5e-13 49.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG45478.1 - 1.7e-11 44.6 0.0 5.6e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG45478.1 - 1.8e-11 44.2 0.0 3.8e-11 43.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG45478.1 - 1.2e-07 31.6 0.0 2.4e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG45478.1 - 3.7e-07 29.7 0.0 6.7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF3419 PF11899.8 KXG45478.1 - 0.00046 19.5 0.0 0.00087 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_8 PF05148.15 KXG45478.1 - 0.0016 18.3 0.0 0.34 10.7 0.0 2.3 2 0 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_24 PF13578.6 KXG45478.1 - 0.0047 17.9 0.0 0.014 16.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 KXG45478.1 - 0.0055 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 KXG45478.1 - 0.021 14.1 0.0 0.54 9.4 0.0 2.1 1 1 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_32 PF13679.6 KXG45478.1 - 0.091 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HlyIII PF03006.20 KXG45479.1 - 3.6e-60 203.5 24.2 4.4e-60 203.2 24.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.13 KXG45479.1 - 0.014 15.5 0.3 0.014 15.5 0.3 2.8 3 1 1 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Asr PF06392.11 KXG45479.1 - 0.055 13.9 1.0 0.13 12.7 1.0 1.6 1 0 0 1 1 1 0 Acid shock protein repeat PIG-S PF10510.9 KXG45480.1 - 5e-187 622.8 0.4 5e-187 622.8 0.4 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-glycan biosynthesis class S protein FmiP_Thoc5 PF09766.9 KXG45480.1 - 6.1e-30 104.7 11.3 8.9e-30 104.2 11.3 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SPATA1_C PF15743.5 KXG45480.1 - 0.017 15.2 2.3 0.017 15.2 2.3 2.3 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus Rootletin PF15035.6 KXG45480.1 - 0.1 12.6 9.5 0.19 11.7 9.5 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion RNase_E_G PF10150.9 KXG45480.1 - 0.12 11.7 4.4 5.2 6.4 0.9 2.2 2 0 0 2 2 2 0 Ribonuclease E/G family Mod_r PF07200.13 KXG45480.1 - 1.3 9.1 11.5 4.6 7.3 3.4 2.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4200 PF13863.6 KXG45480.1 - 1.4 9.4 13.7 1.9 8.9 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF2353 PF09789.9 KXG45480.1 - 6.7 6.0 16.5 36 3.6 16.5 1.9 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) YabA PF06156.13 KXG45480.1 - 6.8 7.4 6.8 40 4.9 0.3 2.6 2 0 0 2 2 2 0 Initiation control protein YabA Menin PF05053.13 KXG45481.1 - 0.12 10.7 2.1 0.16 10.3 2.1 1.1 1 0 0 1 1 1 0 Menin Macoilin PF09726.9 KXG45481.1 - 1.2 7.6 2.9 1.6 7.2 2.9 1.1 1 0 0 1 1 1 0 Macoilin family Sod_Fe_C PF02777.18 KXG45482.1 - 1.7e-17 63.5 0.2 7e-15 55.0 0.2 2.5 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Polyketide_cyc PF03364.20 KXG45483.1 - 4e-23 82.0 0.0 9.4e-23 80.8 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KXG45483.1 - 0.0065 16.7 0.0 0.03 14.6 0.0 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MaoC_dehydrat_N PF13452.6 KXG45484.1 - 0.0016 18.5 0.0 0.35 11.0 0.0 2.4 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Pyr_redox_2 PF07992.14 KXG45485.1 - 1.2e-18 67.4 0.0 4.2e-13 49.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG45485.1 - 4.5e-11 42.5 0.0 6.2e-07 29.0 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXG45485.1 - 9.3e-07 27.9 0.1 0.00023 20.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 KXG45485.1 - 1.1e-05 25.3 0.4 0.022 14.4 0.2 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 KXG45485.1 - 0.00015 21.0 0.1 0.0084 15.2 0.0 2.5 1 1 1 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXG45485.1 - 0.00038 19.6 0.2 0.0017 17.6 0.0 2.1 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 KXG45485.1 - 0.0004 20.5 0.4 0.0014 18.9 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXG45485.1 - 0.00089 18.4 0.1 0.048 12.7 0.0 2.2 1 1 1 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXG45485.1 - 0.0014 18.7 0.2 2.1 8.3 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.17 KXG45485.1 - 0.0028 16.9 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KXG45485.1 - 0.0065 15.8 0.1 0.013 14.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXG45485.1 - 0.012 14.9 0.4 0.046 13.1 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 KXG45485.1 - 0.046 12.9 0.0 7.4 5.6 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KXG45485.1 - 0.057 12.7 0.0 0.16 11.3 0.0 1.7 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KXG45485.1 - 0.071 13.7 0.1 0.23 12.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Na_Ca_ex PF01699.24 KXG45487.1 - 2.7e-33 115.1 35.9 8.3e-17 61.5 18.7 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SUKH-3 PF14433.6 KXG45488.1 - 1.1e-26 94.0 0.0 1.3e-26 93.8 0.0 1.0 1 0 0 1 1 1 1 SUKH-3 immunity protein Imm10 PF15588.6 KXG45489.1 - 9.8e-18 64.2 0.0 3e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 Immunity protein 10 Aldo_ket_red PF00248.21 KXG45490.1 - 1.1e-52 179.1 0.0 1.3e-52 178.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_S64 PF08192.11 KXG45491.1 - 0.075 11.5 0.2 0.15 10.5 0.1 1.4 2 0 0 2 2 2 0 Peptidase family S64 AMP-binding PF00501.28 KXG45492.1 - 4.1e-63 213.4 0.0 5.6e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG45492.1 - 1.1e-05 26.3 0.0 2.2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.21 KXG45493.1 - 6.4e-42 144.0 0.0 8e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXG45493.1 - 1.5e-07 30.7 0.0 2.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXG45493.1 - 1.6e-05 23.7 0.0 2.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KXG45493.1 - 4.4e-05 22.9 0.0 7.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KXG45493.1 - 0.022 14.1 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family ABC2_membrane PF01061.24 KXG45494.1 - 6e-38 130.4 20.6 1.2e-37 129.4 20.6 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KXG45494.1 - 2.3e-23 83.2 0.1 2.3e-23 83.2 0.1 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KXG45494.1 - 1.7e-05 24.8 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KXG45494.1 - 0.0044 16.2 23.9 0.0044 16.2 23.9 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KXG45494.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KXG45494.1 - 0.049 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 KXG45494.1 - 0.05 13.0 1.5 0.28 10.6 0.0 2.4 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXG45494.1 - 0.066 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KXG45494.1 - 0.38 11.2 1.2 0.58 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Laminin_EGF PF00053.24 KXG45494.1 - 8.5 6.6 31.1 0.99 9.6 7.7 3.7 2 1 1 3 3 3 0 Laminin EGF domain Cornichon PF03311.14 KXG45495.1 - 2.2e-49 166.8 14.0 2.5e-49 166.7 14.0 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.32 KXG45496.1 - 6.4e-32 109.1 8.2 6.5e-08 33.1 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG45496.1 - 5.1e-16 58.8 0.0 6.8e-06 26.3 0.0 5.1 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXG45496.1 - 0.096 11.6 0.4 13 4.6 0.1 2.9 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FAD_binding_3 PF01494.19 KXG45497.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Peptidase_M24 PF00557.24 KXG45498.1 - 3e-49 167.6 0.0 3.5e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 MFS_1 PF07690.16 KXG45499.1 - 1.5e-45 155.7 52.6 1.5e-45 155.7 52.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG45499.1 - 9.2e-15 54.4 9.8 9.2e-15 54.4 9.8 3.6 3 1 1 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.13 KXG45499.1 - 1.4e-08 33.6 11.1 1.4e-08 33.6 11.1 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ZZ PF00569.17 KXG45500.1 - 4.9e-12 45.5 4.2 8.3e-12 44.7 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 KXG45500.1 - 9.6e-11 40.5 7.3 5.5e-05 22.4 0.2 3.6 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 KXG45500.1 - 1e-09 38.7 7.4 4.7e-07 30.2 2.0 2.9 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 KXG45500.1 - 2.3e-08 33.3 5.9 0.00027 20.6 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KXG45500.1 - 7.3e-05 22.1 3.2 0.12 12.0 0.2 2.9 2 0 0 2 2 2 2 EF hand C1_2 PF03107.16 KXG45500.1 - 0.0071 16.6 3.8 0.013 15.8 3.8 1.4 1 0 0 1 1 1 1 C1 domain EF-hand_8 PF13833.6 KXG45500.1 - 0.016 15.0 7.9 0.25 11.2 0.3 3.2 3 1 1 4 4 4 0 EF-hand domain pair UNC-93 PF05978.16 KXG45501.1 - 6.2e-16 58.5 2.0 6.2e-16 58.5 2.0 2.8 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KXG45501.1 - 8e-14 51.3 22.3 8e-14 51.3 22.3 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KXG45501.1 - 0.04 12.2 7.1 0.055 11.8 0.7 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PDU_like PF15953.5 KXG45503.1 - 0.013 15.6 0.9 0.054 13.6 0.9 1.8 1 1 0 1 1 1 0 Putative propanediol utilisation Ribosomal_S8 PF00410.19 KXG45504.1 - 4.7e-13 49.2 0.0 3.1e-12 46.6 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S8 Iso_dh PF00180.20 KXG45508.1 - 9.6e-97 324.2 0.0 1.6e-96 323.5 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1769 PF08588.10 KXG45509.1 - 2.4e-26 91.7 0.9 5.1e-26 90.6 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) Beta-lactamase PF00144.24 KXG45511.1 - 3.4e-61 207.3 0.4 4.1e-61 207.1 0.4 1.0 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KXG45511.1 - 0.00071 19.2 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 KXG45511.1 - 0.0023 17.4 1.1 0.017 14.6 0.3 2.1 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Microvir_J PF04726.13 KXG45511.1 - 0.022 14.7 0.2 0.044 13.8 0.2 1.4 1 0 0 1 1 1 0 Microvirus J protein CENP-F_leu_zip PF10473.9 KXG45512.1 - 2e-05 24.7 28.8 0.056 13.5 8.9 5.7 3 1 2 6 6 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SHE3 PF17078.5 KXG45512.1 - 0.00058 19.6 2.2 0.00058 19.6 2.2 4.4 3 1 2 5 5 5 1 SWI5-dependent HO expression protein 3 Suppressor_APC PF11414.8 KXG45512.1 - 0.0023 18.0 4.4 0.68 10.0 0.1 3.9 2 0 0 2 2 2 2 Adenomatous polyposis coli tumour suppressor protein Nup54_57_C PF18570.1 KXG45512.1 - 0.02 14.5 0.4 0.093 12.3 0.4 2.2 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain Sec3_C_2 PF15278.6 KXG45512.1 - 0.046 14.1 0.8 0.21 12.0 0.0 2.6 2 0 0 2 2 2 0 Sec3 exocyst complex subunit Thymosin PF01290.20 KXG45512.1 - 0.15 11.8 1.1 0.52 10.1 0.1 2.5 2 0 0 2 2 2 0 Thymosin beta-4 family GAS PF13851.6 KXG45512.1 - 0.25 10.6 28.8 0.62 9.4 13.2 4.6 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding KLRAQ PF10205.9 KXG45512.1 - 0.47 10.7 15.9 1.9 8.8 4.5 4.6 4 1 1 5 5 5 0 Predicted coiled-coil domain-containing protein AAA_13 PF13166.6 KXG45512.1 - 1.7 7.2 20.2 0.63 8.6 0.1 2.9 2 1 2 4 4 4 0 AAA domain Tup_N PF08581.10 KXG45512.1 - 2.9 8.3 19.8 0.55 10.6 0.7 4.5 3 2 0 4 4 4 0 Tup N-terminal FliD_N PF02465.18 KXG45512.1 - 5.6 7.7 11.1 9.4 7.0 0.2 4.5 4 1 0 4 4 4 0 Flagellar hook-associated protein 2 N-terminus zf-C4H2 PF10146.9 KXG45512.1 - 7.5 6.8 24.6 0.37 11.1 1.2 3.8 2 1 1 3 3 3 0 Zinc finger-containing protein ATG16 PF08614.11 KXG45512.1 - 8.4 6.6 35.1 8.6 6.5 0.9 4.2 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) HSBP1 PF06825.12 KXG45512.1 - 8.4 6.3 8.4 6.5 6.7 0.0 4.5 5 0 0 5 5 5 0 Heat shock factor binding protein 1 DUF3506 PF12014.8 KXG45513.1 - 5.7e-52 175.4 0.0 9e-52 174.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 KXG45513.1 - 7.1e-09 35.4 0.0 1.6e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXG45513.1 - 0.0021 17.9 0.1 0.056 13.3 0.0 2.9 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 KXG45513.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 F-box Dimer_Tnp_hAT PF05699.14 KXG45514.1 - 4.8e-16 58.3 0.0 1.1e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KXG45514.1 - 0.00097 19.5 0.3 0.003 17.9 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) Fungal_trans PF04082.18 KXG45515.1 - 1e-07 31.2 0.0 2.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hydrolase_4 PF12146.8 KXG45516.1 - 4.7e-07 29.3 0.0 6.7e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KXG45516.1 - 1.3e-06 28.1 0.0 4.2e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KXG45516.1 - 2.7e-05 23.9 0.0 3.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KXG45516.1 - 5.3e-05 22.8 0.0 0.00055 19.5 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KXG45516.1 - 0.00012 21.8 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG45516.1 - 0.00066 20.3 0.1 0.00088 19.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 KXG45516.1 - 0.006 15.3 0.1 0.015 14.0 0.1 1.6 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 KXG45516.1 - 0.047 13.6 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal GrpB PF04229.14 KXG45517.1 - 2.3e-49 167.7 0.1 2.8e-49 167.4 0.1 1.1 1 0 0 1 1 1 1 GrpB protein HATPase_c PF02518.26 KXG45518.1 - 1.1e-19 71.0 0.0 2.5e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXG45518.1 - 2.9e-18 66.1 0.1 6.1e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXG45518.1 - 4.3e-13 49.1 0.5 2.6e-12 46.6 0.0 2.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 KXG45518.1 - 0.039 14.6 0.0 0.14 12.8 0.0 2.0 1 0 0 1 1 1 0 GAF domain AA_permease_2 PF13520.6 KXG45519.1 - 1.3e-42 146.2 46.8 1.5e-42 145.9 46.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG45519.1 - 3.2e-22 78.8 39.1 5.3e-22 78.1 39.1 1.3 1 1 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.25 KXG45521.1 - 1.2e-07 31.9 0.0 1.5e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXG45521.1 - 2.2e-07 31.2 0.0 3.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXG45521.1 - 2.7e-07 30.6 0.0 5.3e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Tctex-1 PF03645.13 KXG45522.1 - 2e-35 121.1 0.0 2.4e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family NLE PF08154.12 KXG45522.1 - 0.22 12.1 0.0 0.35 11.4 0.0 1.2 1 0 0 1 1 1 0 NLE (NUC135) domain WD40 PF00400.32 KXG45523.1 - 5.6e-37 125.1 17.0 2e-10 41.1 0.1 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG45523.1 - 1.1e-10 41.7 0.8 0.038 14.3 0.0 4.5 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXG45523.1 - 1.5e-07 30.5 4.5 0.22 10.1 0.1 4.5 3 1 1 4 4 4 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXG45523.1 - 1.7e-06 27.2 0.4 0.34 9.8 0.0 4.5 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KXG45523.1 - 0.00011 21.3 0.1 0.00011 21.3 0.1 2.4 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Hira PF07569.11 KXG45523.1 - 0.037 13.8 1.2 1.3 8.7 0.5 3.3 2 1 1 3 3 3 0 TUP1-like enhancer of split Frtz PF11768.8 KXG45523.1 - 0.11 10.8 0.0 0.17 10.2 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz HPS3_N PF14761.6 KXG45523.1 - 0.16 11.5 0.0 0.56 9.7 0.0 1.7 1 1 0 1 1 1 0 Hermansky-Pudlak syndrome 3 Mod_r PF07200.13 KXG45524.1 - 0.015 15.4 9.0 0.024 14.7 9.0 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein APG6_N PF17675.1 KXG45524.1 - 0.017 15.6 10.1 0.025 15.1 10.1 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 KXG45524.1 - 0.2 11.4 5.5 0.25 11.2 4.6 1.6 1 1 0 1 1 1 0 Septum formation initiator UPF0242 PF06785.11 KXG45524.1 - 0.75 9.9 7.4 1.1 9.3 7.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YscO PF07321.12 KXG45524.1 - 5.8 6.9 11.4 4.7 7.1 7.0 2.0 1 1 1 2 2 2 0 Type III secretion protein YscO ZapB PF06005.12 KXG45524.1 - 6.6 7.3 10.1 1.2 9.7 6.3 1.8 2 1 0 2 2 2 0 Cell division protein ZapB MFS_1 PF07690.16 KXG45525.1 - 4.6e-30 104.7 38.4 1.5e-29 103.1 29.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG45525.1 - 2e-08 33.6 8.0 2e-08 33.6 8.0 2.7 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KXG45525.1 - 1.5e-06 27.0 3.0 1.5e-06 27.0 3.0 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2_4 PF16082.5 KXG45525.1 - 5.4 6.8 5.7 6 6.7 0.1 3.0 3 1 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Mito_carr PF00153.27 KXG45526.1 - 1.7e-57 191.4 0.7 5.9e-20 71.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein AIP3 PF03915.13 KXG45527.1 - 7.5e-152 506.1 0.8 7.5e-152 506.1 0.8 2.0 2 0 0 2 2 2 1 Actin interacting protein 3 Lectin_N PF03954.14 KXG45527.1 - 0.016 15.0 0.0 0.016 15.0 0.0 2.9 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Sec34 PF04136.15 KXG45527.1 - 0.25 11.2 2.9 1.1 9.1 0.1 2.9 3 0 0 3 3 3 0 Sec34-like family NPV_P10 PF05531.12 KXG45527.1 - 0.9 10.0 0.0 0.9 10.0 0.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein LsmAD PF06741.13 KXG45528.1 - 2e-28 98.7 2.3 2e-28 98.7 2.3 1.9 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 KXG45528.1 - 1.9e-20 72.8 0.0 3.9e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Pkinase PF00069.25 KXG45529.1 - 2.8e-11 43.3 0.0 5.5e-11 42.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG45529.1 - 2.7e-07 30.1 0.0 5.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 KXG45529.1 - 5.3e-07 29.4 0.1 0.093 13.0 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 KXG45529.1 - 3.6e-06 27.1 0.0 8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXG45529.1 - 0.0012 19.3 0.1 3.9 8.1 0.1 3.1 2 0 0 2 2 2 2 HEAT-like repeat Kinase-like PF14531.6 KXG45529.1 - 0.0027 17.0 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like HEAT_2 PF13646.6 KXG45529.1 - 0.017 15.5 0.1 0.17 12.3 0.1 2.3 1 1 2 3 3 3 0 HEAT repeats CoA_trans PF01144.23 KXG45529.1 - 0.18 11.2 0.0 0.39 10.1 0.0 1.5 1 0 0 1 1 1 0 Coenzyme A transferase Adaptin_N PF01602.20 KXG45529.1 - 0.19 10.3 0.0 0.83 8.1 0.0 1.6 1 1 0 1 1 1 0 Adaptin N terminal region CLASP_N PF12348.8 KXG45529.1 - 0.19 11.3 0.0 1.2 8.7 0.1 2.0 1 1 1 2 2 2 0 CLASP N terminal Amino_oxidase PF01593.24 KXG45531.1 - 9.9e-60 203.1 0.0 1.1e-59 202.9 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXG45531.1 - 2.8e-09 37.1 0.2 5.4e-09 36.1 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXG45531.1 - 4e-09 36.5 0.3 2.5e-08 33.9 0.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG45531.1 - 0.00042 19.6 0.3 0.0011 18.2 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG45531.1 - 0.0012 18.1 0.1 0.0025 17.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KXG45531.1 - 0.0023 17.1 0.7 0.0042 16.2 0.3 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KXG45531.1 - 0.003 16.3 0.7 0.021 13.6 0.5 2.0 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KXG45531.1 - 0.0031 16.6 0.0 0.16 11.0 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXG45531.1 - 0.0057 15.9 0.1 3.1 7.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXG45531.1 - 0.0063 15.9 0.5 0.0089 15.4 0.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXG45531.1 - 0.0068 16.9 0.5 0.02 15.4 0.3 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG45531.1 - 0.02 14.9 0.2 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXG45531.1 - 0.036 13.3 0.2 0.063 12.5 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KXG45531.1 - 0.18 10.8 0.3 0.31 10.1 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXG45531.1 - 0.31 10.3 0.8 1.2 8.4 0.3 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain zf-MYND PF01753.18 KXG45534.1 - 4e-10 39.6 10.6 7.3e-10 38.8 10.6 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXG45534.1 - 0.54 10.6 8.0 1.7 9.0 7.9 1.9 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF3425 PF11905.8 KXG45535.1 - 1.4e-29 102.6 0.1 2.8e-29 101.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) SlyX PF04102.12 KXG45535.1 - 0.064 13.9 0.4 0.7 10.5 0.3 2.4 2 0 0 2 2 2 0 SlyX bZIP_1 PF00170.21 KXG45535.1 - 1.5 8.9 16.6 12 6.1 13.7 2.7 2 1 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 KXG45535.1 - 3.9 7.6 11.1 2.7 8.1 4.8 2.4 2 0 0 2 2 2 0 Basic region leucine zipper MFS_1 PF07690.16 KXG45536.1 - 5.8e-47 160.3 42.2 5.8e-47 160.3 42.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG45536.1 - 5.2e-07 28.9 33.2 1.5e-06 27.4 33.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter Acetyltransf_1 PF00583.25 KXG45539.1 - 3.3e-11 43.5 0.0 4.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXG45539.1 - 1.7e-07 31.2 0.2 2.4e-07 30.7 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG45539.1 - 1.8e-06 27.8 0.0 3.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KXG45539.1 - 8.2e-05 23.0 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXG45539.1 - 0.0057 16.7 0.3 0.0091 16.1 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SUR7 PF06687.12 KXG45541.1 - 3.2e-43 147.8 8.4 4.2e-43 147.4 8.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family TctB PF07331.11 KXG45541.1 - 0.81 10.0 14.0 0.92 9.8 6.2 3.1 2 1 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family Fig1 PF12351.8 KXG45541.1 - 4.9 7.0 15.8 0.93 9.4 11.7 1.9 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 adh_short_C2 PF13561.6 KXG45542.1 - 2.2e-53 181.2 0.4 2.5e-53 181.0 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG45542.1 - 1.3e-44 152.0 0.9 1.6e-44 151.7 0.9 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG45542.1 - 1.6e-11 44.5 0.7 2.1e-11 44.0 0.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXG45542.1 - 0.00031 20.3 0.1 0.00048 19.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG45542.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_hydro_36N PF16875.5 KXG45542.1 - 0.076 12.6 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 36 N-terminal domain adh_short PF00106.25 KXG45544.1 - 4.6e-15 55.6 0.1 2.7e-06 27.0 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXG45544.1 - 6.5e-07 29.1 0.2 0.00083 19.0 0.0 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase FERM_f0 PF16511.5 KXG45544.1 - 0.039 14.3 0.1 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM DED PF01335.21 KXG45544.1 - 0.12 12.6 0.0 0.48 10.8 0.0 2.0 1 0 0 1 1 1 0 Death effector domain HLH PF00010.26 KXG45545.1 - 6.2e-12 45.3 0.0 3.2e-11 43.0 0.0 2.2 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain tRNA_lig_CPD PF08302.11 KXG45546.1 - 4e-93 311.5 0.0 5.6e-93 311.0 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 KXG45546.1 - 1e-82 277.2 0.1 1.7e-82 276.5 0.1 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KXG45546.1 - 4.7e-49 166.7 0.0 9.1e-49 165.8 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 KXG45546.1 - 0.0058 17.2 0.1 0.072 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Ank_4 PF13637.6 KXG45547.1 - 1.3e-10 41.6 1.0 2e-06 28.2 0.1 2.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG45547.1 - 3.3e-10 40.0 0.0 3.1e-08 33.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG45547.1 - 7.9e-07 28.9 0.3 3.4e-05 23.9 0.1 3.0 3 1 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXG45547.1 - 1.2e-06 29.0 0.1 2.1e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXG45547.1 - 0.0017 18.7 0.1 0.015 15.7 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat YejG PF13989.6 KXG45547.1 - 0.0084 16.5 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 YejG-like protein Mod_r PF07200.13 KXG45548.1 - 6.6e-25 87.9 4.5 8e-25 87.6 4.5 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Fib_alpha PF08702.10 KXG45548.1 - 0.01 16.0 0.1 0.017 15.3 0.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RcbX PF02341.15 KXG45548.1 - 0.027 14.7 0.1 0.047 14.0 0.1 1.4 1 0 0 1 1 1 0 RbcX protein PSK_trans_fac PF07704.11 KXG45548.1 - 0.28 12.0 6.2 0.14 12.9 1.8 2.2 2 0 0 2 2 2 0 Rv0623-like transcription factor PAP2 PF01569.21 KXG45549.1 - 2e-24 85.9 1.4 2e-24 85.9 1.4 2.1 2 1 0 2 2 2 1 PAP2 superfamily Sulf_transp PF04143.14 KXG45549.1 - 4.4e-05 23.2 1.5 4.4e-05 23.2 1.5 1.8 1 1 1 2 2 2 1 Sulphur transport DUF1206 PF06724.11 KXG45549.1 - 0.99 9.5 0.0 0.99 9.5 0.0 3.5 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1206) zf-met PF12874.7 KXG45550.1 - 1.9e-16 59.8 28.6 1.8e-06 28.1 0.4 5.3 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXG45550.1 - 1.1e-15 57.4 26.2 5.6e-05 23.3 1.6 5.9 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KXG45550.1 - 4.1e-14 52.1 22.8 0.066 14.1 0.1 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KXG45550.1 - 4e-10 39.6 30.0 0.1 13.1 0.2 6.5 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KXG45550.1 - 4.5e-10 39.8 25.3 0.012 15.9 0.2 5.9 2 2 4 6 6 6 4 C2H2 type zinc-finger (2 copies) zinc_ribbon_9 PF14369.6 KXG45550.1 - 0.036 14.3 14.9 0.21 11.9 8.5 3.8 2 2 0 2 2 2 0 zinc-ribbon zf-C2H2_6 PF13912.6 KXG45550.1 - 0.036 14.1 21.6 0.32 11.1 0.3 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger LIM PF00412.22 KXG45550.1 - 0.038 14.2 2.1 0.038 14.2 2.1 4.3 2 2 0 3 3 3 0 LIM domain zf-C2H2_11 PF16622.5 KXG45550.1 - 0.059 13.1 8.7 17 5.3 0.3 4.6 4 0 0 4 4 4 0 zinc-finger C2H2-type Zn_ribbon_2 PF12674.7 KXG45550.1 - 0.062 14.0 2.4 0.062 14.0 2.4 2.1 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-H2C2_2 PF13465.6 KXG45550.1 - 0.23 12.0 0.4 0.23 12.0 0.4 6.4 6 0 0 6 6 6 0 Zinc-finger double domain zf-Di19 PF05605.12 KXG45550.1 - 0.28 11.5 0.2 0.28 11.5 0.2 4.6 3 3 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 KXG45550.1 - 2.9 7.8 14.7 2.6 7.9 0.1 4.7 5 1 1 6 6 6 0 C2H2 type zinc-finger (1 copy) Rad50_zn_hook PF04423.14 KXG45550.1 - 8.8 6.3 10.7 15 5.5 0.1 3.7 3 1 1 4 4 4 0 Rad50 zinc hook motif Abhydrolase_1 PF00561.20 KXG45551.1 - 3.5e-18 66.2 0.0 4.5e-17 62.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KXG45551.1 - 4.6e-13 49.2 0.0 9.8e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein ABC_tran PF00005.27 KXG45552.1 - 2.2e-10 41.2 0.0 4.6e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter PTS_EIIC PF02378.18 KXG45552.1 - 0.044 12.8 4.4 0.072 12.1 4.4 1.3 1 0 0 1 1 1 0 Phosphotransferase system, EIIC HAD_2 PF13419.6 KXG45553.1 - 2.6e-10 40.7 0.0 4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXG45553.1 - 9.7e-10 39.1 0.0 3.1e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXG45553.1 - 0.00049 20.1 0.0 0.00087 19.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HTH_1 PF00126.27 KXG45553.1 - 0.028 14.4 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family DNA_pol3_tau_5 PF12170.8 KXG45553.1 - 0.079 13.0 0.2 7.6 6.6 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III tau subunit V interacting with alpha DUF3226 PF11536.8 KXG45553.1 - 0.079 12.6 0.0 0.19 11.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3226) Amino_oxidase PF01593.24 KXG45555.1 - 8.1e-40 137.4 0.1 1.3e-39 136.7 0.1 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXG45555.1 - 5.8e-05 23.2 0.7 0.00013 22.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXG45555.1 - 0.0042 16.4 0.0 0.0078 15.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Ferric_reduct PF01794.19 KXG45556.1 - 3.7e-25 88.5 8.9 9.1e-25 87.2 8.9 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXG45556.1 - 9.9e-15 55.0 0.0 1.4e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXG45556.1 - 5.2e-08 32.9 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXG45556.1 - 2.1e-07 31.6 0.0 5.1e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain PAC3 PF10178.9 KXG45557.1 - 0.083 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Proteasome assembly chaperone 3 CRAL_TRIO PF00650.20 KXG45558.1 - 5.2e-44 149.8 0.0 8.4e-44 149.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXG45558.1 - 7.8e-11 42.0 0.1 2.2e-10 40.6 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXG45558.1 - 1.2e-09 38.5 0.0 2.3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Oxidored_FMN PF00724.20 KXG45559.1 - 1.4e-32 113.3 0.0 2.2e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ADH_zinc_N PF00107.26 KXG45560.1 - 7.8e-10 38.8 0.0 1.5e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG45560.1 - 1.5e-09 39.0 0.0 4.5e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG45560.1 - 1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_1 PF00561.20 KXG45561.1 - 4.9e-30 105.0 0.2 8.6e-30 104.2 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG45561.1 - 1e-26 93.7 0.2 8.3e-18 64.5 0.2 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXG45561.1 - 1.8e-17 64.7 0.0 2.2e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXG45561.1 - 2.6e-07 30.3 0.4 0.0085 15.6 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KXG45561.1 - 0.00042 20.2 0.0 0.0015 18.3 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF1749 PF08538.10 KXG45561.1 - 0.00083 18.5 0.1 0.0017 17.5 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.7 KXG45561.1 - 0.0043 16.8 0.1 0.55 10.0 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KXG45561.1 - 0.0043 16.7 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KXG45561.1 - 0.01 15.4 0.0 0.13 11.8 0.0 2.4 3 0 0 3 3 3 0 Dienelactone hydrolase family DUF915 PF06028.11 KXG45561.1 - 0.022 14.1 0.1 0.058 12.7 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.13 KXG45561.1 - 0.039 13.8 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase AMP-binding PF00501.28 KXG45562.1 - 5.6e-78 262.4 0.0 6.9e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG45562.1 - 1.9e-09 38.4 0.0 5.7e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ADC PF06314.11 KXG45563.1 - 1e-09 38.3 0.0 1.4e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) DJ-1_PfpI PF01965.24 KXG45564.1 - 1.1e-09 38.4 0.0 6.3e-09 35.9 0.0 2.1 1 1 1 2 2 2 1 DJ-1/PfpI family Aldedh PF00171.22 KXG45565.1 - 5.2e-67 226.3 0.0 1.7e-65 221.4 0.0 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family ADH_zinc_N PF00107.26 KXG45566.1 - 7.6e-12 45.3 0.2 1.6e-11 44.3 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG45566.1 - 1.1e-06 28.4 0.6 3.7e-05 23.6 0.2 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXG45566.1 - 3.8e-06 28.0 0.0 9.2e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Oxidored_FMN PF00724.20 KXG45567.1 - 2.1e-62 211.4 0.0 2.4e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aldo_ket_red PF00248.21 KXG45568.1 - 1.5e-46 158.9 0.0 3.2e-46 157.9 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 KXG45568.1 - 2.4e-14 53.3 0.0 4.2e-08 32.9 0.0 2.4 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXG45568.1 - 1.8e-07 31.0 0.0 0.00054 19.6 0.0 2.5 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG45568.1 - 0.00053 19.9 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 KR domain GFA PF04828.14 KXG45569.1 - 6.1e-07 29.7 0.2 1.2e-06 28.8 0.2 1.5 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme PHD_Oberon PF07227.11 KXG45569.1 - 0.088 12.7 4.3 0.32 10.9 0.1 2.2 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein DIOX_N PF14226.6 KXG45570.1 - 1.5e-18 67.6 0.0 2.5e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG45570.1 - 5.5e-17 62.1 0.0 1.5e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NPR3 PF03666.13 KXG45571.1 - 6.2e-153 509.9 5.4 8e-153 509.6 0.0 2.7 3 0 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 KXG45571.1 - 0.12 11.1 0.0 0.36 9.5 0.0 1.7 2 0 0 2 2 2 0 Nitrogen permease regulator 2 Na_trans_assoc PF06512.13 KXG45571.1 - 0.29 11.4 4.7 0.34 11.2 0.0 2.7 3 0 0 3 3 3 0 Sodium ion transport-associated Mago-bind PF09282.10 KXG45571.1 - 7 6.6 9.3 0.2 11.6 2.1 2.2 2 0 0 2 2 2 0 Mago binding TLP-20 PF06088.11 KXG45571.1 - 8.9 6.2 6.4 2.1 8.2 0.1 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) La PF05383.17 KXG45572.1 - 4e-19 68.4 0.5 7.1e-19 67.6 0.5 1.4 1 0 0 1 1 1 1 La domain Band_7 PF01145.25 KXG45573.1 - 5.9e-31 107.9 0.9 1.4e-30 106.7 0.9 1.6 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KXG45573.1 - 5.3e-23 80.8 1.1 1.3e-22 79.5 1.1 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 KXG45573.1 - 0.022 14.0 0.2 0.036 13.4 0.2 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein Band_7_1 PF13421.6 KXG45573.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Hira PF07569.11 KXG45576.1 - 2.9e-84 282.2 0.0 5.4e-84 281.4 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KXG45576.1 - 5.6e-28 96.6 21.3 7e-05 23.5 0.0 9.0 7 1 1 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG45576.1 - 5.8e-14 52.2 0.0 0.019 15.3 0.0 6.1 5 1 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KXG45576.1 - 2.5e-09 36.8 0.0 8.1e-09 35.1 0.0 2.0 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 KXG45576.1 - 0.00011 22.0 2.2 0.43 10.6 0.0 4.9 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXG45576.1 - 0.0038 16.2 0.3 5 6.0 0.0 3.8 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KXG45576.1 - 0.015 13.4 0.0 0.03 12.3 0.0 1.4 1 0 0 1 1 1 0 IKI3 family YchF-GTPase_C PF06071.13 KXG45577.1 - 3.1e-34 117.0 0.1 6.8e-34 115.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KXG45577.1 - 2.4e-16 59.9 0.0 7.2e-16 58.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXG45577.1 - 0.00074 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KXG45577.1 - 0.0013 18.7 0.0 0.0036 17.3 0.0 1.7 2 0 0 2 2 2 1 TGS domain AAA_14 PF13173.6 KXG45577.1 - 0.084 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain PUA PF01472.20 KXG45578.1 - 4.1e-14 52.3 0.2 5.3e-14 51.9 0.2 1.2 1 0 0 1 1 1 1 PUA domain Pre-PUA PF17832.1 KXG45578.1 - 2.5e-06 28.1 0.3 3.7e-06 27.5 0.3 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain AMP-binding PF00501.28 KXG45579.1 - 2.3e-63 214.3 0.0 3.1e-63 213.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KXG45579.1 - 2.9e-51 174.1 0.0 4.1e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KXG45579.1 - 1.9e-14 53.7 0.1 1.2e-13 51.1 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXG45579.1 - 6.7e-13 48.8 0.1 3.7e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KXG45579.1 - 3.2e-06 26.3 0.0 6.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KXG45579.1 - 6.1e-05 23.9 0.1 0.00016 22.6 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 KXG45579.1 - 0.0016 17.9 0.0 0.0067 15.9 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXG45579.1 - 0.029 13.5 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KXG45579.1 - 0.13 12.7 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TAL_FSA PF00923.19 KXG45580.1 - 1.5e-33 116.4 0.0 2e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Aldo_ket_red PF00248.21 KXG45581.1 - 8.1e-43 146.7 0.0 1.1e-42 146.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ABM PF03992.16 KXG45582.1 - 7.2e-05 22.8 0.0 7.2e-05 22.8 0.0 2.2 3 0 0 3 3 3 1 Antibiotic biosynthesis monooxygenase CENP-B_dimeris PF09026.10 KXG45582.1 - 7.3 7.1 12.0 18 5.8 12.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GPI-anchored PF10342.9 KXG45583.1 - 2.1e-20 73.2 1.1 2.1e-20 73.2 1.1 2.8 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Alpha-amylase PF00128.24 KXG45584.1 - 4.3e-27 95.6 0.0 1.1e-26 94.3 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KXG45584.1 - 3.4e-07 28.9 0.4 0.11 10.6 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Alpha-amylase PF00128.24 KXG45585.1 - 1e-49 170.0 2.8 1.5e-49 169.4 2.8 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KXG45585.1 - 1.2e-31 108.8 0.2 2.4e-31 107.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Alpha-amylase PF00128.24 KXG45586.1 - 1.8e-17 63.9 0.3 1.8e-17 63.9 0.3 2.6 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KXG45586.1 - 7.9e-15 55.2 0.1 1.4e-14 54.4 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KXG45586.1 - 7.2e-05 22.4 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXG45586.1 - 0.061 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Big_5 PF13205.6 KXG45586.1 - 0.11 13.2 0.3 0.32 11.7 0.3 1.8 1 0 0 1 1 1 0 Bacterial Ig-like domain CUB_2 PF02408.20 KXG45586.1 - 1.5 8.6 4.2 0.66 9.8 1.1 2.1 2 0 0 2 2 2 0 CUB-like domain Fringe PF02434.16 KXG45588.1 - 0.00011 21.7 0.5 0.0011 18.5 0.5 2.0 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KXG45588.1 - 0.01 15.7 0.0 0.029 14.2 0.0 1.8 1 1 0 1 1 1 0 Galactosyltransferase PAP2_3 PF14378.6 KXG45589.1 - 8.8e-23 81.0 24.3 1.5e-22 80.2 18.7 3.0 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KXG45589.1 - 4.6 7.9 16.3 0.075 13.6 4.2 3.5 3 1 0 3 3 3 0 PAP2 superfamily C-terminal DUF4234 PF14018.6 KXG45590.1 - 0.0039 17.3 0.0 0.0071 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4234) MLANA PF14991.6 KXG45590.1 - 0.072 13.4 0.2 0.51 10.6 0.0 2.4 2 1 1 3 3 3 0 Protein melan-A GREB1 PF15782.5 KXG45590.1 - 5.2 4.0 11.5 5.4 4.0 11.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF572 PF04502.13 KXG45590.1 - 5.7 6.5 8.9 8 6.0 8.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF5521 PF17659.1 KXG45590.1 - 6.1 4.6 9.2 7.8 4.2 9.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) RNase_H PF00075.24 KXG45591.1 - 1.9e-21 76.7 0.0 3.4e-21 75.9 0.0 1.4 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 KXG45591.1 - 9.2e-05 22.3 0.0 0.019 14.8 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase-like VPS9 PF02204.18 KXG45592.1 - 1e-17 64.2 0.0 2.6e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 KXG45592.1 - 3.4e-16 59.1 0.9 3.3e-12 46.4 0.0 4.8 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXG45592.1 - 6.2e-12 45.9 0.0 0.00062 20.3 0.1 3.7 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) PX PF00787.24 KXG45592.1 - 7.6e-07 29.1 0.4 2.1e-06 27.7 0.4 1.7 1 0 0 1 1 1 1 PX domain Ribosomal_S11 PF00411.19 KXG45592.1 - 5.2e-05 23.6 0.0 0.0026 18.2 0.0 2.5 2 0 0 2 2 2 1 Ribosomal protein S11 Ank PF00023.30 KXG45592.1 - 0.00012 22.3 0.1 3.5 8.2 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KXG45592.1 - 0.00071 20.1 0.0 0.072 13.7 0.0 3.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG45592.1 - 0.013 16.0 0.3 32 5.5 0.0 5.0 5 0 0 5 5 5 0 Ankyrin repeat Tim44 PF04280.15 KXG45593.1 - 5.2e-37 127.2 0.0 2.3e-36 125.1 0.0 2.1 2 0 0 2 2 2 1 Tim44-like domain CLN3 PF02487.17 KXG45593.1 - 1.1 8.2 4.6 0.24 10.4 1.3 1.6 2 1 0 2 2 2 0 CLN3 protein SGTA_dimer PF16546.5 KXG45594.1 - 8.4e-26 89.5 0.4 1.4e-25 88.8 0.4 1.4 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KXG45594.1 - 1.3e-15 56.4 4.8 3e-06 26.8 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXG45594.1 - 9.2e-15 53.5 6.5 4.2e-05 23.3 0.5 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXG45594.1 - 1e-11 44.1 6.3 8.6e-06 25.6 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXG45594.1 - 1.2e-10 40.9 6.5 2.6e-08 33.4 1.3 3.1 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.6 KXG45594.1 - 9.8e-08 32.5 5.0 0.00011 22.7 2.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXG45594.1 - 9.2e-07 28.5 0.2 0.074 13.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXG45594.1 - 1.1e-06 28.8 4.3 0.0013 19.0 1.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXG45594.1 - 1.7e-06 28.0 0.8 0.016 15.5 0.2 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXG45594.1 - 2e-05 25.0 3.8 0.018 15.5 1.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXG45594.1 - 5e-05 23.8 7.3 0.44 11.5 0.1 3.7 2 1 2 4 4 3 3 Tetratricopeptide repeat STI1 PF17830.1 KXG45594.1 - 0.00025 20.9 7.7 0.0019 18.1 3.0 2.6 2 0 0 2 2 2 1 STI1 domain TPR_9 PF13371.6 KXG45594.1 - 0.0032 17.6 0.4 0.051 13.7 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat XPC-binding PF09280.11 KXG45594.1 - 0.0052 16.5 0.8 0.011 15.4 0.8 1.6 1 0 0 1 1 1 1 XPC-binding domain BTAD PF03704.17 KXG45594.1 - 0.015 15.7 2.2 0.1 13.1 0.4 2.3 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 KXG45594.1 - 0.052 14.2 6.6 0.3 11.8 0.2 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXG45594.1 - 0.068 13.1 5.1 29 4.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RIC1 PF07064.13 KXG45595.1 - 3.5e-84 282.2 0.2 6.6e-84 281.3 0.2 1.5 1 0 0 1 1 1 1 RIC1 Aldedh PF00171.22 KXG45596.1 - 2.7e-114 382.3 0.0 3.2e-114 382.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXG45596.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1890 PF09001.11 KXG45598.1 - 0.042 14.3 0.0 0.075 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) DUF4939 PF16297.5 KXG45598.1 - 0.094 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Bac_luciferase PF00296.20 KXG45599.1 - 3.8e-69 233.5 0.0 4.6e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Inhibitor_I78 PF11720.8 KXG45600.1 - 2e-07 31.0 0.0 2.2e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 KXG45600.1 - 0.014 16.1 0.0 0.016 15.9 0.0 1.2 1 0 0 1 1 1 0 Potato inhibitor I family Alpha-L-AF_C PF06964.12 KXG45601.1 - 3.9e-29 101.9 0.0 5.6e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Sugar_tr PF00083.24 KXG45602.1 - 2.8e-103 346.2 15.0 3.2e-103 346.0 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG45602.1 - 3.9e-31 108.3 22.8 2.4e-22 79.3 2.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nefa_Nip30_N PF10187.9 KXG45603.1 - 2.6e-31 108.1 13.8 2.6e-31 108.1 13.8 2.1 2 1 1 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 KXG45603.1 - 0.067 12.8 21.1 0.083 12.5 21.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) FAM104 PF15434.6 KXG45603.1 - 8.9 6.9 12.5 0.069 13.7 3.9 1.9 2 1 0 2 2 2 0 Family 104 Aldo_ket_red PF00248.21 KXG45604.1 - 1.4e-43 149.2 0.0 8.4e-42 143.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_6 PF01341.17 KXG45606.1 - 4.2e-107 358.4 1.2 5.3e-107 358.1 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CK_II_beta PF01214.18 KXG45607.1 - 1.2e-75 253.3 0.1 1.8e-75 252.7 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF1180 PF06679.12 KXG45607.1 - 0.013 16.0 0.1 0.024 15.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CxC5 PF18718.1 KXG45607.1 - 0.024 14.7 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases Abhydrolase_6 PF12697.7 KXG45608.1 - 9e-07 29.7 2.2 1.1e-06 29.4 2.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG45608.1 - 0.0021 17.4 0.0 0.0077 15.5 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KXG45608.1 - 0.004 17.3 0.0 0.0053 16.9 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 KXG45608.1 - 0.0052 16.5 0.0 0.027 14.1 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KXG45608.1 - 0.034 14.0 0.6 0.084 12.7 0.5 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Chloroa_b-bind PF00504.21 KXG45608.1 - 0.093 13.3 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyll A-B binding protein DUF2974 PF11187.8 KXG45608.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) C_GCAxxG_C_C PF09719.10 KXG45608.1 - 0.15 12.3 0.1 1.2 9.4 0.1 2.1 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) JAB PF01398.21 KXG45609.1 - 1.2e-09 38.2 0.5 4.2e-08 33.2 0.5 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Lactamase_B PF00753.27 KXG45611.1 - 7.4e-18 65.3 1.7 2.4e-17 63.6 1.7 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXG45611.1 - 1.2e-05 25.0 0.1 1.9e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.14 KXG45612.1 - 1.2e-09 37.9 0.0 4.4e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG45612.1 - 0.018 14.7 0.3 0.028 14.0 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXG45612.1 - 0.096 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Mito_carr PF00153.27 KXG45613.1 - 9.3e-43 144.1 3.1 1.5e-17 63.3 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein NmrA PF05368.13 KXG45616.1 - 3.7e-27 95.4 0.0 7.8e-27 94.3 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG45616.1 - 7.1e-06 26.0 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 KXG45616.1 - 0.096 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.19 KXG45616.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Tail_P2_I PF09684.10 KXG45617.1 - 0.11 12.4 0.1 3.6 7.5 0.0 2.2 1 1 0 2 2 2 0 Phage tail protein (Tail_P2_I) APAF1_C PF17908.1 KXG45617.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 APAF-1 helical domain Mito_fiss_reg PF05308.11 KXG45618.1 - 0.16 12.0 0.0 0.16 12.0 0.0 13.6 6 3 7 14 14 14 0 Mitochondrial fission regulator HMG_box_2 PF09011.10 KXG45619.1 - 1.2e-09 38.6 1.6 6.9e-09 36.2 0.2 2.6 2 0 0 2 2 2 1 HMG-box domain HMG_box PF00505.19 KXG45619.1 - 6.4e-09 36.1 0.3 6.4e-09 36.1 0.3 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_5 PF14887.6 KXG45619.1 - 0.0021 18.0 0.2 0.021 14.8 0.0 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box 5 TraF PF13728.6 KXG45619.1 - 1.3 8.8 6.9 2.3 8.0 6.9 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Ribosomal_L18_c PF14204.6 KXG45619.1 - 5.1 8.1 11.9 20 6.2 0.3 3.3 3 0 0 3 3 3 0 Ribosomal L18 C-terminal region DEAD PF00270.29 KXG45620.1 - 1.3e-49 168.3 0.0 2.8e-48 164.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG45620.1 - 3.9e-26 91.6 0.0 1.7e-25 89.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain MFMR_assoc PF16596.5 KXG45621.1 - 0.032 14.7 3.7 0.05 14.1 3.7 1.4 1 0 0 1 1 1 0 Disordered region downstream of MFMR DUF4329 PF14220.6 KXG45622.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4329) Sugar_tr PF00083.24 KXG45623.1 - 1.3e-93 314.3 21.5 1.6e-93 314.0 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG45623.1 - 5.4e-32 111.1 58.4 1.4e-29 103.2 29.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXG45623.1 - 0.00016 20.1 14.8 0.0024 16.2 0.8 3.1 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family CDPS PF16715.5 KXG45625.1 - 0.0038 16.9 0.3 0.012 15.3 0.2 1.8 1 1 1 2 2 2 1 Cyclodipeptide synthase DUF1580 PF07618.11 KXG45625.1 - 0.021 14.4 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1580) Phage_lambda_P PF06992.11 KXG45625.1 - 0.024 14.4 0.1 0.034 13.9 0.1 1.4 1 0 0 1 1 1 0 Replication protein P Fib_alpha PF08702.10 KXG45625.1 - 0.54 10.4 2.4 7.1 6.8 0.2 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TTR-52 PF01060.23 KXG45626.1 - 1.8 9.3 4.5 10 6.9 1.9 2.8 1 1 1 2 2 2 0 Transthyretin-like family Acetyltransf_3 PF13302.7 KXG45627.1 - 4.3e-19 69.6 0.0 5e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG45627.1 - 8e-07 29.3 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KXG45627.1 - 0.059 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein RL PF17797.1 KXG45627.1 - 0.22 11.5 0.1 0.85 9.6 0.1 1.9 2 0 0 2 2 2 0 RL domain PNP_UDP_1 PF01048.20 KXG45628.1 - 3e-09 36.5 0.9 1.7e-08 34.1 0.9 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Ses_B PF17046.5 KXG45628.1 - 0.0054 16.6 1.9 0.0096 15.9 1.9 1.4 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein TPR_10 PF13374.6 KXG45629.1 - 9.3e-67 219.3 0.0 3.6e-12 45.7 0.0 7.9 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 KXG45629.1 - 3.3e-53 177.9 7.4 2.4e-14 53.4 0.0 6.2 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 KXG45629.1 - 2.2e-26 89.9 0.7 0.0029 17.5 0.0 6.8 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 KXG45629.1 - 5e-15 54.7 0.1 0.88 10.1 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXG45629.1 - 2e-14 52.7 0.4 0.58 10.1 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_4 PF07721.14 KXG45629.1 - 4.3e-14 51.6 2.0 0.2 12.4 0.1 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXG45629.1 - 1.8e-11 44.5 0.0 2 9.2 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXG45629.1 - 2.6e-11 42.7 3.8 3.9 7.8 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXG45629.1 - 6.6e-08 33.0 0.0 10 6.7 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KXG45629.1 - 1.3e-07 31.3 6.7 1.5e-06 27.8 6.6 2.1 1 1 1 2 2 2 1 MalT-like TPR region A2M PF00207.22 KXG45629.1 - 9e-06 25.5 1.5 1.6 8.6 0.1 4.6 2 1 2 4 4 4 1 Alpha-2-macroglobulin family DUF1697 PF08002.11 KXG45629.1 - 1.9e-05 25.1 0.1 0.35 11.3 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1697) NB-ARC PF00931.22 KXG45629.1 - 8.2e-05 21.9 0.0 0.0063 15.7 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain AAA_16 PF13191.6 KXG45629.1 - 0.00036 20.9 0.2 0.0014 19.1 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain PPR PF01535.20 KXG45629.1 - 0.0015 18.6 0.0 1.1e+02 3.4 0.0 5.4 5 0 0 5 5 5 0 PPR repeat AAA_22 PF13401.6 KXG45629.1 - 0.0031 17.8 0.0 0.007 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain TPR_14 PF13428.6 KXG45629.1 - 0.0075 17.0 7.7 1.3e+02 3.8 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXG45629.1 - 0.012 15.8 1.9 1.2e+02 3.3 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat Urocanase_N PF17391.2 KXG45629.1 - 0.014 15.1 0.1 22 4.8 0.0 4.3 2 2 2 4 4 4 0 Urocanase N-terminal domain NACHT PF05729.12 KXG45629.1 - 0.037 14.0 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 KXG45629.1 - 0.079 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 KXG45629.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TPR_6 PF13174.6 KXG45629.1 - 1.7 9.4 5.9 1.8e+02 3.1 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat CorA PF01544.18 KXG45630.1 - 4.9e-06 26.1 6.6 2.7e-05 23.7 6.6 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein adh_short PF00106.25 KXG45631.1 - 3.2e-38 131.2 0.0 4.4e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG45631.1 - 7.6e-37 127.1 0.2 5.3e-33 114.5 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG45631.1 - 2.8e-14 53.4 0.1 1.9e-13 50.7 0.1 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXG45631.1 - 0.00022 20.8 0.1 0.0034 16.9 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXG45633.1 - 3.4e-18 66.2 0.0 5.2e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXG45633.1 - 1.5e-17 63.9 0.1 2.7e-17 63.1 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXG45633.1 - 5e-05 22.9 0.0 0.00025 20.6 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KXG45633.1 - 0.0021 18.2 0.7 0.0044 17.1 0.1 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 KXG45633.1 - 0.0044 17.1 0.0 0.008 16.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 KXG45633.1 - 0.0078 16.6 0.1 0.015 15.7 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXG45633.1 - 0.029 13.4 0.0 0.088 11.8 0.0 1.9 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KXG45633.1 - 0.07 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.12 KXG45633.1 - 0.085 12.0 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein CBM_15 PF03426.14 KXG45634.1 - 2.4 7.7 6.5 0.32 10.6 1.0 2.1 2 0 0 2 2 2 0 Carbohydrate binding domain (family 15) AAT PF03417.16 KXG45636.1 - 5.9e-48 163.5 0.0 7.2e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF333 PF03891.15 KXG45636.1 - 0.084 13.1 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF333) DUF5042 PF16445.5 KXG45636.1 - 0.18 10.1 0.0 0.27 9.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5042) DIOX_N PF14226.6 KXG45637.1 - 9.3e-17 61.9 0.1 1.4e-16 61.3 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG45637.1 - 5e-15 55.8 0.0 1.2e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Condensation PF00668.20 KXG45638.1 - 2e-275 913.5 3.6 1.2e-96 324.2 0.3 5.0 5 0 0 5 5 5 4 Condensation domain AMP-binding PF00501.28 KXG45638.1 - 3.2e-246 816.7 0.0 4.4e-85 285.8 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme PP-binding PF00550.25 KXG45638.1 - 9.5e-46 154.0 0.4 4.2e-14 52.7 0.0 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site Thioesterase PF00975.20 KXG45638.1 - 1.2e-29 104.0 0.0 2.7e-29 103.0 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain AMP-binding_C PF13193.6 KXG45638.1 - 5.5e-29 101.0 0.0 2.2e-09 38.1 0.0 3.8 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KXG45638.1 - 0.00062 18.7 0.3 0.017 14.0 0.0 3.1 4 0 0 4 4 4 1 GH3 auxin-responsive promoter LpxD PF04613.14 KXG45638.1 - 0.0097 15.7 0.1 2.1 8.1 0.1 2.9 2 0 0 2 2 2 1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Abhydrolase_6 PF12697.7 KXG45638.1 - 0.071 13.7 0.0 0.23 12.0 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family AATase PF07247.12 KXG45638.1 - 0.072 11.6 0.1 0.32 9.5 0.1 2.1 2 0 0 2 2 2 0 Alcohol acetyltransferase Acyl-CoA_dh_1 PF00441.24 KXG45639.1 - 9.2e-05 22.7 0.0 0.00015 22.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HMG-CoA_red PF00368.18 KXG45640.1 - 5.5e-91 305.3 0.0 6.6e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase AdoHcyase PF05221.17 KXG45641.1 - 5e-128 426.4 0.0 4.2e-73 246.1 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KXG45641.1 - 1.2e-81 272.5 2.7 2.5e-81 271.5 2.7 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXG45641.1 - 2.1e-06 27.2 0.1 4.6e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KXG45641.1 - 0.00047 19.8 0.2 0.00087 18.9 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KXG45641.1 - 0.007 16.6 0.1 0.016 15.5 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain Oxidored_nitro PF00148.19 KXG45641.1 - 0.026 13.3 0.2 0.26 10.0 0.1 2.2 2 1 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase ELFV_dehydrog PF00208.21 KXG45641.1 - 0.027 14.2 0.1 0.044 13.5 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Urocanase PF01175.18 KXG45641.1 - 0.081 12.6 0.3 0.16 11.6 0.3 1.4 1 0 0 1 1 1 0 Urocanase Rossmann-like domain UPF0261 PF06792.11 KXG45642.1 - 1.4e-155 518.2 0.2 1.6e-155 518.0 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Glyco_hydro_43 PF04616.14 KXG45643.1 - 7.6e-10 38.6 1.0 2.5e-09 36.9 1.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 RT_RNaseH PF17917.1 KXG45644.1 - 8e-10 39.0 0.1 1.3e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KXG45644.1 - 0.0013 18.7 0.1 0.0038 17.2 0.0 1.8 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase Kelch_3 PF13415.6 KXG45650.1 - 0.00018 21.7 0.4 0.00018 21.7 0.4 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KXG45650.1 - 0.0041 17.4 7.5 0.0081 16.4 0.1 4.0 4 1 1 5 5 5 1 Kelch motif Mid2 PF04478.12 KXG45650.1 - 0.0043 16.9 0.4 0.0092 15.8 0.4 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Kelch_4 PF13418.6 KXG45650.1 - 0.0066 16.4 8.2 0.0096 15.9 0.4 4.4 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 KXG45650.1 - 0.0075 15.8 0.2 0.12 12.0 0.1 2.9 3 0 0 3 3 3 1 Kelch motif TMEM154 PF15102.6 KXG45650.1 - 0.0095 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF908 PF06012.12 KXG45650.1 - 5.2 6.4 9.7 0.42 10.0 1.9 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) HAT PF02184.16 KXG45651.1 - 8.3e-23 80.1 68.8 3.1e-15 55.8 3.7 12.3 14 0 0 14 14 13 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KXG45651.1 - 3.7e-20 70.9 20.4 0.00012 22.6 0.2 10.3 8 3 5 13 13 12 5 Tetratricopeptide repeat TPR_19 PF14559.6 KXG45651.1 - 2.8e-17 63.0 0.7 2.3e-06 28.0 0.0 6.7 8 0 0 8 8 7 3 Tetratricopeptide repeat Suf PF05843.14 KXG45651.1 - 3.3e-14 53.6 15.6 0.00032 20.8 1.0 5.8 3 1 1 5 5 5 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 KXG45651.1 - 1.9e-12 46.6 4.2 0.23 11.9 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXG45651.1 - 2.1e-08 33.7 4.0 9.6 6.7 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXG45651.1 - 6.7e-06 25.8 13.8 0.18 12.0 0.0 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_15 PF13429.6 KXG45651.1 - 8.3e-05 21.9 15.5 0.32 10.2 0.2 6.2 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXG45651.1 - 0.0013 18.5 2.3 8.5 6.4 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXG45651.1 - 0.0023 18.0 3.2 10 6.3 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXG45651.1 - 0.0062 17.1 16.8 11 6.9 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KXG45651.1 - 0.013 14.6 24.1 0.81 8.8 0.8 5.8 4 3 1 5 5 5 0 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 KXG45651.1 - 0.035 14.8 9.5 4.4 8.1 0.0 6.1 8 1 0 8 8 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXG45651.1 - 0.72 10.0 11.1 23 5.1 0.4 6.0 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KXG45651.1 - 2.1 8.7 20.0 7 7.0 0.1 7.0 9 1 0 9 9 9 0 Tetratricopeptide repeat Nop PF01798.18 KXG45652.1 - 1.8e-60 204.3 0.1 2.4e-60 203.9 0.1 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KXG45652.1 - 3.1e-46 157.2 0.4 1e-45 155.6 0.4 1.9 1 1 0 1 1 1 1 Prp31 C terminal domain PhyH PF05721.13 KXG45654.1 - 0.0027 18.0 0.0 0.005 17.1 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Aldo_ket_red PF00248.21 KXG45656.1 - 1.6e-66 224.5 0.0 1.8e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-H2C2_2 PF13465.6 KXG45657.1 - 1.1e-06 28.7 10.2 2.7e-06 27.6 0.9 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KXG45657.1 - 1.3e-05 25.1 1.3 0.022 14.8 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXG45657.1 - 2.2e-05 24.7 0.8 2.2e-05 24.7 0.8 3.1 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXG45657.1 - 0.00042 20.9 9.1 0.0035 18.1 0.5 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 KXG45657.1 - 0.00056 20.5 14.4 0.076 13.7 0.0 4.3 3 1 1 4 4 4 2 FOXP coiled-coil domain SUIM_assoc PF16619.5 KXG45657.1 - 0.003 17.6 0.9 0.003 17.6 0.9 2.5 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 zf-C2H2_jaz PF12171.8 KXG45657.1 - 0.0058 16.9 1.0 0.29 11.5 0.3 2.8 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KXG45657.1 - 0.03 14.1 0.8 0.29 11.0 0.0 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type XRCC4 PF06632.12 KXG45657.1 - 0.073 11.9 0.0 0.073 11.9 0.0 2.2 3 0 0 3 3 3 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 SNF2_N PF00176.23 KXG45658.1 - 2e-56 191.2 0.0 3.2e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KXG45658.1 - 1e-24 86.1 2.4 4.6e-17 61.7 0.2 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 KXG45658.1 - 4.1e-21 75.2 1.0 1.2e-20 73.7 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KXG45658.1 - 1.2e-18 67.5 0.0 3.3e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cdh1_DBD_1 PF18196.1 KXG45658.1 - 9.2e-07 29.2 0.8 1e-05 25.9 0.1 4.6 4 1 1 5 5 5 2 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 KXG45658.1 - 7.4e-05 22.8 0.0 0.0018 18.3 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 KXG45658.1 - 0.028 14.6 1.3 0.073 13.2 0.0 2.4 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain SLIDE PF09111.10 KXG45658.1 - 0.043 13.8 0.0 0.32 11.0 0.0 2.5 3 0 0 3 3 3 0 SLIDE ABC_tran PF00005.27 KXG45659.1 - 7.8e-35 120.4 0.0 2.1e-16 60.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 KXG45659.1 - 9.8e-14 50.9 5.1 9.8e-14 50.9 5.1 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 KXG45659.1 - 1.1e-10 41.4 1.7 0.0033 16.9 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXG45659.1 - 9.8e-10 38.7 3.7 0.28 10.9 1.7 4.4 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KXG45659.1 - 7.1e-06 26.5 0.1 0.0099 16.3 0.1 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXG45659.1 - 9.5e-06 26.1 0.0 0.032 14.6 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KXG45659.1 - 3.6e-05 23.7 0.1 0.27 10.9 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain Rad17 PF03215.15 KXG45659.1 - 6.1e-05 23.0 0.1 0.022 14.7 0.0 2.8 2 1 1 3 3 3 1 Rad17 P-loop domain Fer4 PF00037.27 KXG45659.1 - 8.6e-05 22.2 2.5 8.6e-05 22.2 2.5 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_22 PF13401.6 KXG45659.1 - 0.00013 22.2 0.0 0.026 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXG45659.1 - 0.00017 21.5 0.0 0.57 10.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 KXG45659.1 - 0.00045 20.4 0.0 0.078 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXG45659.1 - 0.00065 19.4 0.2 0.71 9.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KXG45659.1 - 0.0013 19.2 0.0 1.8 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXG45659.1 - 0.0014 19.0 1.1 0.33 11.4 0.1 2.9 3 0 0 3 3 2 1 RNA helicase Fer4_21 PF14697.6 KXG45659.1 - 0.0021 18.1 11.5 0.0037 17.3 11.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_24 PF13479.6 KXG45659.1 - 0.0028 17.4 2.1 0.14 11.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KXG45659.1 - 0.0033 17.4 0.2 0.035 14.1 0.1 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KXG45659.1 - 0.0034 17.3 2.0 0.2 11.6 0.0 2.6 3 0 0 3 3 2 1 NACHT domain AAA_7 PF12775.7 KXG45659.1 - 0.0039 16.7 0.4 0.065 12.8 0.2 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region Fer4_6 PF12837.7 KXG45659.1 - 0.0053 16.8 12.7 0.0092 16.0 2.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_23 PF13476.6 KXG45659.1 - 0.0068 16.9 1.1 0.44 11.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 KXG45659.1 - 0.008 16.3 15.3 0.025 14.7 1.5 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 KXG45659.1 - 0.0092 15.7 0.3 1.6 8.3 0.0 2.7 3 0 0 3 3 2 1 Thymidylate kinase SRP54 PF00448.22 KXG45659.1 - 0.011 15.4 3.6 0.14 11.8 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KXG45659.1 - 0.017 14.3 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 KXG45659.1 - 0.028 14.1 0.8 1.3 8.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KXG45659.1 - 0.035 14.1 0.2 1.7 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.6 KXG45659.1 - 0.037 12.7 0.0 0.073 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXG45659.1 - 0.043 14.0 0.1 6.4 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.6 KXG45659.1 - 0.047 13.9 11.3 0.098 12.8 11.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain DUF815 PF05673.13 KXG45659.1 - 0.054 12.6 0.1 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 KXG45659.1 - 0.087 12.7 2.1 1.7 8.5 0.1 2.7 2 0 0 2 2 2 0 NTPase Fer4_16 PF13484.6 KXG45659.1 - 0.093 13.7 0.3 0.093 13.7 0.3 2.8 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain VirE PF05272.11 KXG45659.1 - 0.098 12.4 0.1 8.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E SbcCD_C PF13558.6 KXG45659.1 - 0.13 12.5 0.0 15 5.9 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_17 PF13534.6 KXG45659.1 - 0.14 12.7 0.2 0.14 12.7 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_14 PF13173.6 KXG45659.1 - 0.16 12.0 0.1 10 6.2 0.1 2.8 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 KXG45659.1 - 0.21 10.5 0.3 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_8 PF13183.6 KXG45659.1 - 0.38 11.3 6.7 0.36 11.3 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 KXG45659.1 - 0.42 11.2 11.8 0.071 13.7 1.5 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain MukB PF04310.12 KXG45659.1 - 0.49 10.2 1.5 30 4.3 0.1 2.7 3 0 0 3 3 3 0 MukB N-terminal PduV-EutP PF10662.9 KXG45659.1 - 0.54 10.0 3.1 0.41 10.4 0.1 2.3 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_2 PF12797.7 KXG45659.1 - 2 8.7 9.5 0.3 11.3 1.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain FF PF01846.19 KXG45660.1 - 6.8e-54 179.9 15.9 3.9e-16 58.9 1.2 6.8 6 0 0 6 6 6 6 FF domain WW PF00397.26 KXG45660.1 - 7.4e-19 67.5 11.1 1.8e-09 37.5 0.2 2.6 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 KXG45660.1 - 0.0012 19.5 11.5 0.42 11.3 0.3 4.4 2 1 2 4 4 4 2 p190-A and -B Rho GAPs FF domain Glyco_hyd_101C PF17451.2 KXG45660.1 - 2.8 8.3 8.0 4.6 7.6 0.4 2.7 1 1 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Cytochrom_B562 PF07361.11 KXG45660.1 - 4.4 8.0 8.6 0.38 11.4 0.5 3.2 4 0 0 4 4 4 0 Cytochrome b562 Trs65 PF12735.7 KXG45661.1 - 9.2e-102 340.7 0.1 1.2e-101 340.3 0.1 1.1 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.12 KXG45662.1 - 2.7e-19 69.2 0.2 2.7e-19 69.2 0.2 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.19 KXG45663.1 - 4.4e-149 496.5 1.0 4.9e-149 496.4 1.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 KXG45663.1 - 0.0096 15.9 0.7 0.17 11.9 0.0 2.8 3 0 0 3 3 3 1 PA domain DUF3530 PF12048.8 KXG45663.1 - 0.027 13.9 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DSS1_SEM1 PF05160.13 KXG45664.1 - 4.8e-20 71.4 15.0 2e-18 66.2 15.0 2.1 1 1 0 1 1 1 1 DSS1/SEM1 family DUF3808 PF10300.9 KXG45665.1 - 1.9e-159 531.4 0.3 2.4e-159 531.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) MFS_1 PF07690.16 KXG45666.1 - 3.5e-40 138.0 31.0 3.5e-40 138.0 31.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM43 PF07787.12 KXG45666.1 - 6.6 6.0 7.0 1.4 8.3 1.9 2.3 2 0 0 2 2 2 0 Transmembrane protein 43 AMP-binding PF00501.28 KXG45667.1 - 6.5e-290 960.6 0.0 3.7e-80 269.6 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 KXG45667.1 - 2.4e-256 850.7 0.0 3.5e-54 184.2 0.0 9.7 9 1 0 9 9 9 8 Condensation domain PP-binding PF00550.25 KXG45667.1 - 1.5e-47 159.8 7.4 7.1e-10 39.1 0.1 5.8 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXG45667.1 - 4.5e-06 27.5 0.1 0.82 10.7 0.0 4.7 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KXG45667.1 - 0.054 12.2 0.0 4.2 5.9 0.0 3.5 4 0 0 4 4 4 0 Transferase family DUF5122 PF17164.4 KXG45667.1 - 0.76 10.1 4.7 25 5.3 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller ABC_tran PF00005.27 KXG45668.1 - 1.6e-51 174.4 0.0 2.9e-27 95.8 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXG45668.1 - 3.2e-28 99.2 27.1 1.6e-19 70.6 12.5 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KXG45668.1 - 7e-10 38.7 4.4 0.0039 16.7 0.1 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXG45668.1 - 2.9e-06 27.8 0.1 0.0015 18.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXG45668.1 - 8.7e-06 25.7 1.2 0.00056 19.9 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KXG45668.1 - 9.9e-06 25.2 2.0 0.0011 18.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KXG45668.1 - 2.1e-05 25.1 2.2 0.013 16.0 0.4 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KXG45668.1 - 2.3e-05 24.7 2.1 0.0058 16.9 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXG45668.1 - 9.6e-05 22.3 8.1 0.00095 19.1 0.1 3.4 3 1 1 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KXG45668.1 - 0.00015 21.8 0.2 0.13 12.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 KXG45668.1 - 0.00025 20.8 0.7 0.16 11.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXG45668.1 - 0.00028 21.2 0.0 0.11 12.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 KXG45668.1 - 0.00049 19.7 0.3 0.028 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 KXG45668.1 - 0.00053 19.7 0.6 0.63 9.7 0.2 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 KXG45668.1 - 0.00054 20.4 0.5 0.24 11.8 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KXG45668.1 - 0.00096 18.7 0.5 0.87 9.1 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_15 PF13175.6 KXG45668.1 - 0.0018 18.1 0.3 0.048 13.4 0.2 2.4 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 KXG45668.1 - 0.0036 16.4 0.4 0.3 10.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Viral_helicase1 PF01443.18 KXG45668.1 - 0.0049 16.6 0.2 0.64 9.7 0.1 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 KXG45668.1 - 0.0054 16.9 0.0 0.24 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXG45668.1 - 0.0066 16.4 0.1 0.5 10.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.18 KXG45668.1 - 0.012 15.0 0.2 4.1 6.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.14 KXG45668.1 - 0.013 15.4 0.3 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase_2 PF01637.18 KXG45668.1 - 0.025 14.5 0.6 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_ATPase PF09818.9 KXG45668.1 - 0.027 13.3 0.2 0.027 13.3 0.2 3.2 5 0 0 5 5 4 0 Predicted ATPase of the ABC class Roc PF08477.13 KXG45668.1 - 0.031 14.5 0.8 15 5.8 0.0 3.3 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KXG45668.1 - 0.039 13.1 2.5 3.4 6.8 0.1 2.5 2 1 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 KXG45668.1 - 0.039 14.5 0.3 1.5 9.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KXG45668.1 - 0.04 12.9 0.3 5.5 5.9 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 KXG45668.1 - 0.043 13.8 0.6 2.7 8.0 0.1 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KXG45668.1 - 0.07 13.0 0.5 0.17 11.8 0.5 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_11 PF13086.6 KXG45668.1 - 0.091 12.5 0.1 2.7 7.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXG45668.1 - 0.091 12.5 1.9 3 7.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KXG45668.1 - 0.1 13.0 0.9 13 6.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 KXG45668.1 - 0.11 11.2 0.1 0.25 10.1 0.1 1.5 1 0 0 1 1 1 0 Adenovirus IVa2 protein NTPase_1 PF03266.15 KXG45668.1 - 0.12 12.3 2.3 5.5 6.9 0.2 2.4 2 0 0 2 2 2 0 NTPase Dynamin_N PF00350.23 KXG45668.1 - 0.15 12.1 0.7 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 KXG45668.1 - 0.15 11.8 5.8 9.6 5.9 0.1 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein PIF1 PF05970.14 KXG45668.1 - 0.16 11.1 0.1 0.54 9.4 0.0 1.8 2 0 0 2 2 2 0 PIF1-like helicase DEAD PF00270.29 KXG45668.1 - 0.16 11.7 0.7 0.56 9.9 0.7 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase Guanylate_kin PF00625.21 KXG45668.1 - 0.16 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase cobW PF02492.19 KXG45668.1 - 0.16 11.5 2.8 3.4 7.2 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 KXG45668.1 - 0.19 11.1 0.4 12 5.3 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Septin PF00735.18 KXG45668.1 - 0.27 10.5 0.4 9.7 5.4 0.1 2.2 2 0 0 2 2 2 0 Septin PRK PF00485.18 KXG45668.1 - 0.41 10.3 1.4 13 5.5 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 KXG45668.1 - 1.6 9.0 4.6 0.22 11.8 0.5 1.7 2 0 0 2 2 1 0 AAA domain MACPF PF01823.19 KXG45669.1 - 9.8e-07 29.1 1.1 3.2e-06 27.4 0.0 2.4 2 1 0 2 2 2 1 MAC/Perforin domain DUF4527 PF15030.6 KXG45669.1 - 0.074 12.5 0.4 0.12 11.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) Abhydrolase_1 PF00561.20 KXG45670.1 - 3.3e-21 76.1 0.0 1.2e-20 74.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG45670.1 - 2.6e-15 57.7 0.3 3.3e-15 57.3 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KXG45670.1 - 2.6e-06 27.7 0.0 4.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 KXG45670.1 - 0.00097 18.5 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXG45670.1 - 0.11 11.2 0.0 0.88 8.2 0.0 1.9 2 0 0 2 2 2 0 Ndr family ZF-HD_dimer PF04770.12 KXG45670.1 - 0.14 12.5 0.0 0.36 11.2 0.0 1.6 2 0 0 2 2 2 0 ZF-HD protein dimerisation region Nup160 PF11715.8 KXG45671.1 - 7e-158 526.6 1.6 1e-157 526.1 1.6 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Rad51 PF08423.11 KXG45671.1 - 3.9e-126 419.5 0.1 7.3e-126 418.6 0.0 1.5 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.6 KXG45671.1 - 7.2e-09 35.5 0.0 1.8e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KXG45671.1 - 4.2e-08 33.0 0.0 7.3e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KXG45671.1 - 4.2e-05 24.1 0.4 0.00013 22.5 0.4 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 KXG45671.1 - 0.0024 17.2 0.5 0.0068 15.8 0.5 1.8 1 1 0 1 1 1 1 KaiC LysM PF01476.20 KXG45673.1 - 2.7e-05 24.1 0.1 6.2e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 LysM domain Chitin_bind_1 PF00187.19 KXG45673.1 - 0.0036 17.7 18.6 0.0036 17.7 18.6 3.0 3 1 0 3 3 3 1 Chitin recognition protein HC2 PF07382.11 KXG45673.1 - 0.0051 16.9 27.5 0.0077 16.3 27.5 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Peptidase_C39_2 PF13529.6 KXG45673.1 - 0.046 14.3 5.8 0.094 13.3 5.8 1.5 1 0 0 1 1 1 0 Peptidase_C39 like family Endomucin PF07010.12 KXG45673.1 - 0.46 10.4 29.7 0.71 9.8 29.7 1.2 1 0 0 1 1 1 0 Endomucin ALS2CR11 PF15729.5 KXG45673.1 - 1.5 7.9 11.0 1.9 7.5 11.0 1.1 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 Hid1 PF12722.7 KXG45673.1 - 3 5.9 12.0 3.9 5.5 12.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_A4 PF01828.17 KXG45674.1 - 2.4e-82 275.5 10.3 2.8e-82 275.2 10.3 1.1 1 0 0 1 1 1 1 Peptidase A4 family Aa_trans PF01490.18 KXG45675.1 - 8.7e-21 74.1 19.3 1.5e-14 53.6 4.2 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein MFS_1 PF07690.16 KXG45676.1 - 7e-44 150.2 40.4 1.1e-43 149.5 31.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG45676.1 - 2.8e-10 39.7 9.3 2.8e-10 39.7 9.3 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXG45676.1 - 4e-06 25.5 4.8 4e-06 25.5 4.8 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF5536 PF17688.1 KXG45676.1 - 0.0042 17.0 0.2 0.0081 16.1 0.0 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5536) Lactamase_B_2 PF12706.7 KXG45677.1 - 1.6e-13 50.7 0.0 3e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXG45677.1 - 1.3e-09 38.1 0.0 1.8e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Peptidase_M19 PF01244.21 KXG45678.1 - 2.4e-101 339.1 0.3 3.7e-101 338.5 0.3 1.2 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Fungal_trans PF04082.18 KXG45678.1 - 0.01 14.9 0.0 0.021 13.8 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain NLPC_P60 PF00877.19 KXG45679.1 - 1.9e-19 69.6 0.1 3.4e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 NlpC/P60 family SH3_16 PF18348.1 KXG45679.1 - 0.00034 20.3 4.7 0.0012 18.6 1.0 3.1 3 1 0 3 3 3 1 Bacterial dipeptidyl-peptidase Sh3 domain DUF1175 PF06672.11 KXG45679.1 - 0.037 13.7 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) JmjN PF02375.17 KXG45680.1 - 0.16 11.9 0.4 2.7 8.0 0.1 2.7 3 0 0 3 3 3 0 jmjN domain Mito_carr PF00153.27 KXG45681.1 - 9.8e-69 227.4 0.7 3.9e-23 81.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 KXG45681.1 - 0.0033 17.6 0.0 0.35 11.1 0.0 2.6 3 0 0 3 3 3 1 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Chromate_transp PF02417.15 KXG45681.1 - 0.052 13.7 0.5 4.3 7.5 0.1 2.6 3 0 0 3 3 3 0 Chromate transporter PT-VENN PF04829.13 KXG45681.1 - 1 9.5 0.1 1 9.5 0.1 2.4 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif HeLo PF14479.6 KXG45682.1 - 1.1e-37 129.9 0.2 1.5e-37 129.4 0.2 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation HET-s_218-289 PF11558.8 KXG45682.1 - 0.59 10.2 4.6 0.32 11.0 0.4 2.7 3 1 1 4 4 4 0 Het-s 218-289 Ank_2 PF12796.7 KXG45683.1 - 3.5e-32 110.8 0.0 1.8e-09 38.0 0.0 5.5 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG45683.1 - 1.1e-21 76.9 0.8 1.2e-06 28.9 0.3 5.5 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KXG45683.1 - 1.8e-21 75.6 0.2 0.0025 18.2 0.0 7.9 7 1 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KXG45683.1 - 2e-21 75.8 2.6 3.5e-06 27.2 0.1 5.2 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG45683.1 - 3.4e-21 73.1 0.7 0.012 16.0 0.0 8.8 9 0 0 9 9 9 5 Ankyrin repeat GMC_oxred_N PF00732.19 KXG45684.1 - 5.1e-53 180.4 0.0 6.9e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG45684.1 - 1.9e-34 119.3 0.0 2.9e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KXG45684.1 - 0.00042 19.6 0.1 0.00077 18.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KXG45684.1 - 0.0028 16.9 0.0 0.65 9.2 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXG45684.1 - 0.0061 15.6 0.3 0.011 14.9 0.1 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXG45684.1 - 0.0083 15.2 0.3 0.24 10.4 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXG45684.1 - 0.0085 16.3 0.3 0.023 14.9 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXG45684.1 - 0.014 14.9 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG45684.1 - 0.031 13.5 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Catalase PF00199.19 KXG45685.1 - 1.4e-173 577.4 0.0 1.6e-173 577.2 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KXG45685.1 - 5.6e-13 48.9 0.0 1.3e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive MFS_1 PF07690.16 KXG45688.1 - 6.2e-33 114.2 30.1 1.5e-28 99.7 25.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXG45688.1 - 3.2e-07 30.0 2.8 3.2e-07 30.0 2.8 2.1 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB GDPD PF03009.17 KXG45689.1 - 2.8e-28 99.3 0.0 4.8e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family HNH_2 PF13391.6 KXG45690.1 - 1.7e-11 44.0 0.1 5e-11 42.6 0.1 1.8 2 0 0 2 2 2 1 HNH endonuclease Shisa PF13908.6 KXG45691.1 - 3.3 7.9 4.4 0.69 10.1 0.3 1.8 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator MFS_1 PF07690.16 KXG45692.1 - 3.8e-10 39.2 14.6 9.2e-10 38.0 13.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG45692.1 - 0.014 14.3 0.9 0.021 13.7 0.9 1.4 1 0 0 1 1 1 0 MFS_1 like family DUF4064 PF13273.6 KXG45692.1 - 6.4 7.1 11.2 5.8 7.3 0.3 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF4064) TauD PF02668.16 KXG45693.1 - 1.1e-59 202.4 0.1 1.5e-59 202.0 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Aa_trans PF01490.18 KXG45695.1 - 6.7e-27 94.2 34.2 8.5e-27 93.9 34.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 KXG45695.1 - 9.2e-08 31.3 42.8 2.8e-06 26.5 42.8 2.2 1 1 0 1 1 1 1 Amino acid permease DAO PF01266.24 KXG45695.1 - 0.099 12.2 3.0 0.14 11.7 3.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Tmemb_55A PF09788.9 KXG45695.1 - 1.2 8.1 3.6 0.37 9.9 0.3 1.8 2 0 0 2 2 2 0 Transmembrane protein 55A adh_short PF00106.25 KXG45696.1 - 4.4e-30 104.6 0.0 4.9e-28 97.9 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG45696.1 - 4.4e-24 85.3 0.0 4.5e-23 82.0 0.0 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 KXG45696.1 - 1.2e-18 67.4 0.1 6.6e-18 64.9 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG45696.1 - 5.6e-14 51.9 0.4 1.2e-13 50.9 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain KR PF08659.10 KXG45696.1 - 6.2e-10 39.3 0.0 1.1e-06 28.7 0.0 3.1 3 0 0 3 3 3 2 KR domain ADH_zinc_N_2 PF13602.6 KXG45696.1 - 7e-08 33.6 0.2 3.6e-07 31.3 0.0 2.2 2 1 1 3 3 3 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXG45696.1 - 0.0019 17.5 1.6 0.003 16.9 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KXG45696.1 - 0.076 13.2 0.0 3.8 7.7 0.0 2.4 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.21 KXG45696.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Lactamase_B PF00753.27 KXG45697.1 - 4.2e-09 36.7 0.1 7.1e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXG45697.1 - 0.039 13.5 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain HNHc_6 PF16784.5 KXG45697.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative HNHc nuclease MFS_1 PF07690.16 KXG45698.1 - 2e-32 112.5 44.5 2.5e-32 112.2 41.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OSTbeta PF15048.6 KXG45698.1 - 0.065 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF1129 PF06570.11 KXG45698.1 - 0.39 10.2 0.0 0.39 10.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Sarcolipin PF05366.11 KXG45698.1 - 9.6 6.0 8.8 22 4.9 0.3 3.1 3 0 0 3 3 3 0 Sarcolipin Ras PF00071.22 KXG45699.1 - 7.9e-31 106.8 0.1 4.9e-29 101.0 0.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXG45699.1 - 0.00012 22.3 0.0 0.00029 21.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KXG45699.1 - 0.024 14.2 0.1 0.17 11.4 0.1 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Arf PF00025.21 KXG45699.1 - 0.037 13.5 0.0 0.2 11.1 0.0 1.9 1 1 1 2 2 2 0 ADP-ribosylation factor family PAS_9 PF13426.7 KXG45700.1 - 1.7e-26 92.5 0.0 3e-19 69.2 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 KXG45700.1 - 1.2e-20 73.6 0.0 6.7e-12 45.5 0.0 4.5 5 1 0 5 5 5 3 PAS fold GATA PF00320.27 KXG45700.1 - 8.9e-14 50.8 6.6 1.8e-13 49.8 6.6 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 KXG45700.1 - 7e-13 48.6 0.0 0.00028 20.9 0.0 3.7 3 1 0 3 3 3 3 PAS fold PAS_4 PF08448.10 KXG45700.1 - 1.2e-07 31.9 0.0 0.0051 17.0 0.0 3.7 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.6 KXG45700.1 - 0.0017 18.4 0.0 0.047 13.8 0.0 3.0 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.7 KXG45700.1 - 0.0044 17.0 0.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 PAS domain Nudix_N_2 PF14803.6 KXG45700.1 - 0.049 13.6 1.2 0.11 12.5 1.2 1.6 1 0 0 1 1 1 0 Nudix N-terminal LETM1 PF07766.13 KXG45701.1 - 1.2e-08 34.7 0.1 8.4e-06 25.3 0.1 2.4 1 1 0 1 1 1 1 LETM1-like protein Nrap_D4 PF17405.2 KXG45702.1 - 4.8e-62 209.1 0.0 8.9e-62 208.2 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KXG45702.1 - 4.5e-58 195.6 1.1 9.2e-58 194.6 1.1 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 KXG45702.1 - 4.4e-48 162.9 0.0 3e-46 157.0 0.0 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 KXG45702.1 - 1.2e-44 152.2 0.0 3.7e-44 150.6 0.1 1.8 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap PF03813.14 KXG45702.1 - 7.9e-40 136.4 0.1 1.9e-39 135.2 0.1 1.7 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 KXG45702.1 - 1.7e-28 99.5 0.0 5.8e-28 97.8 0.0 2.0 2 0 0 2 2 2 1 Nrap protein domain 6 Cys_Met_Meta_PP PF01053.20 KXG45703.1 - 1.3e-32 112.8 0.0 1.8e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXG45703.1 - 0.00087 18.6 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II MRP-L20 PF12824.7 KXG45705.1 - 1.5e-62 210.6 3.2 1.7e-62 210.4 3.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 KXG45705.1 - 0.002 18.2 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 Neugrin HTH_32 PF13565.6 KXG45705.1 - 0.0045 17.6 0.5 0.29 11.8 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain CtsR PF05848.11 KXG45705.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 CtsR N-terminal HTH domain Peptidase_M20 PF01546.28 KXG45706.1 - 3.4e-31 108.6 0.0 4.2e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXG45706.1 - 1.5e-12 47.4 0.0 2.4e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXG45706.1 - 0.043 13.5 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M28 PLDc PF00614.22 KXG45707.1 - 2.2e-14 52.9 0.2 1.3e-06 28.3 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KXG45707.1 - 2.2e-13 50.3 0.0 1.3e-06 28.3 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 KXG45707.1 - 9.2e-07 28.8 0.0 6.6e-06 26.1 0.0 2.6 2 1 0 2 2 2 1 PX domain DUF313 PF03754.13 KXG45707.1 - 0.12 12.6 0.1 0.47 10.7 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF313) Hydrolase_4 PF12146.8 KXG45708.1 - 0.078 12.2 0.0 0.6 9.3 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Helicase_C_2 PF13307.6 KXG45709.1 - 5.8e-50 169.8 0.0 1.4e-49 168.6 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KXG45709.1 - 1.5e-49 168.0 0.0 3.3e-49 166.9 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 Ribosomal_L27A PF00828.19 KXG45709.1 - 6.9e-21 75.3 0.0 1.7e-20 74.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A HBB PF06777.11 KXG45709.1 - 0.0026 17.5 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 Helical and beta-bridge domain DUF1319 PF07028.11 KXG45709.1 - 0.16 12.2 1.1 0.67 10.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) MAJIN PF15077.6 KXG45709.1 - 1.2 8.9 6.2 4 7.2 4.2 2.3 2 0 0 2 2 2 0 Membrane-anchored junction protein Sel1 PF08238.12 KXG45710.1 - 7.8e-20 70.9 14.3 4.6e-07 30.3 0.0 6.7 7 0 0 7 7 7 4 Sel1 repeat TPR_1 PF00515.28 KXG45710.1 - 0.00016 21.3 0.1 0.00093 18.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXG45710.1 - 0.026 15.3 2.3 0.055 14.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXG45710.1 - 0.1 12.8 0.0 0.1 12.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TBPIP PF07106.13 KXG45711.1 - 4.1e-11 42.6 0.0 7.4e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain CENP-F_leu_zip PF10473.9 KXG45711.1 - 0.0025 17.9 0.9 0.0049 16.9 0.9 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Macoilin PF09726.9 KXG45711.1 - 0.0048 15.5 0.6 0.0055 15.3 0.6 1.1 1 0 0 1 1 1 1 Macoilin family Penicillinase_R PF03965.16 KXG45711.1 - 0.021 15.2 0.4 0.06 13.7 0.1 1.9 2 0 0 2 2 2 0 Penicillinase repressor PspA_IM30 PF04012.12 KXG45711.1 - 0.038 13.6 3.7 0.23 11.0 3.7 2.0 1 1 0 1 1 1 0 PspA/IM30 family DUF5082 PF16888.5 KXG45711.1 - 0.058 13.7 2.1 5.9 7.2 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) zf-C4H2 PF10146.9 KXG45711.1 - 0.065 13.5 2.4 0.11 12.8 2.2 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein DUF4407 PF14362.6 KXG45711.1 - 0.067 12.5 1.2 0.098 12.0 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 KXG45711.1 - 0.084 13.3 7.0 0.19 12.2 0.8 2.7 2 1 1 3 3 3 0 Cell division protein ZapB Wbp11 PF09429.10 KXG45711.1 - 0.099 13.1 3.7 2 8.9 0.9 2.5 1 1 1 2 2 2 0 WW domain binding protein 11 Phosphodiest PF01663.22 KXG45711.1 - 0.11 12.1 0.8 0.68 9.5 0.1 1.9 1 1 1 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Leu_zip PF15294.6 KXG45711.1 - 0.14 11.7 1.6 0.15 11.6 0.8 1.5 1 1 0 1 1 1 0 Leucine zipper DUF3818 PF12825.7 KXG45711.1 - 0.14 11.1 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) ABC_tran_CTD PF16326.5 KXG45711.1 - 0.21 11.8 12.1 2.1 8.7 5.6 3.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF2514 PF10721.9 KXG45711.1 - 0.44 10.6 4.6 0.29 11.2 2.4 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2514) DUF4140 PF13600.6 KXG45711.1 - 0.56 10.7 6.8 81 3.8 6.7 2.5 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF1192 PF06698.11 KXG45711.1 - 0.7 10.0 10.3 5 7.3 0.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) APG6_N PF17675.1 KXG45711.1 - 0.76 10.3 12.6 0.1 13.1 4.5 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region CCDC-167 PF15188.6 KXG45711.1 - 2.7 8.4 7.2 2.6 8.4 1.4 2.6 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Prefoldin_2 PF01920.20 KXG45711.1 - 4.9 7.1 8.2 4.5 7.3 0.1 2.8 3 1 1 4 4 3 0 Prefoldin subunit zf-CCCH PF00642.24 KXG45712.1 - 3e-12 46.1 10.4 2.3e-06 27.4 1.9 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXG45712.1 - 2.3e-10 40.0 9.0 1.4e-06 27.9 2.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXG45712.1 - 2.9e-09 36.7 16.1 3.9e-05 23.5 1.8 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KXG45712.1 - 4.8e-09 36.9 5.5 0.00028 21.5 0.4 2.5 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 KXG45712.1 - 0.00047 20.4 0.1 0.00082 19.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KXG45712.1 - 0.0026 18.2 13.9 0.17 12.4 3.2 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Bromodomain PF00439.25 KXG45713.1 - 7.4e-39 131.7 4.4 2.4e-19 69.2 0.6 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KXG45713.1 - 3e-18 65.9 1.2 8.1e-18 64.4 1.2 1.8 1 0 0 1 1 1 1 BAH domain DUF5542 PF17696.1 KXG45713.1 - 0.092 12.9 0.2 0.32 11.1 0.2 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5542) HHH_6 PF14579.6 KXG45713.1 - 0.13 12.5 1.2 16 5.8 0.0 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix motif Nucleo_P87 PF07267.11 KXG45713.1 - 0.47 9.3 7.7 3.1 6.5 0.3 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 TFIIA PF03153.13 KXG45713.1 - 1.4 8.9 13.8 4 7.3 0.5 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CENP-B_dimeris PF09026.10 KXG45713.1 - 6.8 7.1 10.8 2.4 8.6 7.5 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CDC45 PF02724.14 KXG45713.1 - 7.8 4.7 10.9 0.56 8.4 1.8 2.1 2 0 0 2 2 2 0 CDC45-like protein OTU PF02338.19 KXG45714.1 - 1.6e-07 31.9 0.0 2.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.8 KXG45714.1 - 0.06 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 YukD PF08817.10 KXG45714.1 - 0.095 13.4 0.0 0.17 12.6 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Peptidase_C65 PF10275.9 KXG45714.1 - 0.15 11.5 0.0 1.6 8.1 0.0 2.1 1 1 1 2 2 2 0 Peptidase C65 Otubain Pkinase PF00069.25 KXG45715.1 - 2.6e-42 145.0 0.0 1.9e-38 132.3 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG45715.1 - 1.5e-08 34.3 0.0 0.0013 18.1 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXG45715.1 - 0.0021 18.0 0.1 1.3 8.9 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXG45715.1 - 0.0069 15.2 0.0 0.011 14.5 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXG45715.1 - 0.075 12.3 0.0 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Herpes_pp85 PF04637.12 KXG45715.1 - 0.55 8.6 2.5 1.1 7.7 2.3 1.5 1 1 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Cnd1_N PF12922.7 KXG45716.1 - 2.2e-60 203.3 0.1 4.7e-60 202.2 0.1 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 KXG45716.1 - 6.6e-48 162.8 2.7 1.4e-42 145.5 0.5 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXG45716.1 - 1.6e-11 44.5 0.4 5.2e-06 26.8 0.0 3.8 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.22 KXG45716.1 - 1.6e-08 34.0 10.8 0.06 13.6 0.0 6.6 5 1 2 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 KXG45716.1 - 6.9e-07 28.2 8.5 0.0026 16.4 0.5 4.3 3 2 0 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 KXG45716.1 - 1.5e-05 25.4 12.1 0.19 12.3 0.1 6.3 6 0 0 6 6 6 2 HEAT-like repeat RTP1_C1 PF10363.9 KXG45716.1 - 5.3e-05 23.4 0.1 0.052 13.7 0.0 3.5 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 KXG45716.1 - 0.00025 20.3 3.1 0.0012 18.1 1.2 3.0 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain FlbD PF06289.11 KXG45716.1 - 0.06 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins Oxysterol_BP PF01237.18 KXG45717.1 - 4.5e-55 187.0 0.0 7.5e-53 179.7 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Peptidase_C12 PF01088.21 KXG45718.1 - 6.3e-62 209.1 0.1 1.4e-61 207.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KXG45718.1 - 0.00032 20.5 0.5 0.00086 19.2 0.5 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases I-set PF07679.16 KXG45719.1 - 3.6e-06 27.0 0.1 0.097 12.7 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KXG45719.1 - 0.017 15.7 0.0 6.3 7.5 0.0 3.7 3 0 0 3 3 3 0 Immunoglobulin domain Arylesterase PF01731.20 KXG45720.1 - 0.076 13.2 0.0 0.59 10.4 0.0 2.6 2 1 0 2 2 2 0 Arylesterase N_BRCA1_IG PF16158.5 KXG45721.1 - 7.5e-31 106.9 0.0 1.9e-30 105.6 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KXG45721.1 - 1.3e-23 82.5 52.6 3.9e-08 33.0 3.7 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type Auxin_inducible PF02519.14 KXG45721.1 - 0.0099 16.0 0.0 0.032 14.4 0.0 1.8 1 0 0 1 1 1 1 Auxin responsive protein C1_2 PF03107.16 KXG45721.1 - 0.41 11.0 52.4 0.068 13.5 10.6 4.5 4 0 0 4 4 4 0 C1 domain Btz PF09405.10 KXG45722.1 - 7.3e-31 107.1 4.1 7.3e-31 107.1 4.1 1.8 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding RRM_1 PF00076.22 KXG45723.1 - 7.1e-24 83.4 0.7 6.2e-13 48.4 0.1 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXG45723.1 - 1.8e-05 24.8 0.0 0.019 15.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif Ribosomal_L27e PF01777.18 KXG45723.1 - 0.16 12.4 3.3 0.57 10.6 3.3 2.0 1 0 0 1 1 1 0 Ribosomal L27e protein family Nup35_RRM_2 PF14605.6 KXG45723.1 - 0.17 11.9 0.0 9.9 6.3 0.1 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CCDC106 PF15794.5 KXG45723.1 - 0.62 9.7 13.0 0.16 11.6 3.4 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 RPA43_OB PF17875.1 KXG45723.1 - 4 8.1 11.2 13 6.5 0.2 3.0 3 1 0 3 3 3 0 RPA43 OB domain in RNA Pol I Ino80_Iec3 PF14612.6 KXG45724.1 - 9e-77 258.9 3.5 1.5e-76 258.2 3.5 1.3 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling ECR1_N PF14382.6 KXG45725.1 - 2.6e-16 59.1 0.5 5.2e-16 58.2 0.5 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KXG45725.1 - 0.0024 18.2 0.2 0.0046 17.3 0.2 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KXG45725.1 - 0.033 14.8 0.5 1.7 9.3 0.1 2.8 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 IFRD PF05004.13 KXG45726.1 - 4.6e-91 305.1 1.6 6.3e-91 304.7 1.6 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 KXG45726.1 - 0.023 15.1 0.1 2.1 8.8 0.0 2.9 2 0 0 2 2 2 0 HEAT repeats Cnd3 PF12719.7 KXG45726.1 - 0.03 13.5 2.9 0.036 13.2 0.0 2.2 1 1 1 2 2 2 0 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 KXG45726.1 - 0.073 13.6 0.1 26 5.5 0.0 3.4 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.22 KXG45726.1 - 0.27 11.6 5.0 11 6.6 0.0 4.4 6 0 0 6 6 6 0 HEAT repeat Oxysterol_BP PF01237.18 KXG45727.1 - 9.4e-119 396.6 0.0 4e-118 394.5 0.0 2.1 2 0 0 2 2 2 1 Oxysterol-binding protein SH2_2 PF14633.6 KXG45727.1 - 1e-85 286.6 0.0 2e-85 285.6 0.0 1.5 1 0 0 1 1 1 1 SH2 domain PH_8 PF15409.6 KXG45727.1 - 3e-38 130.0 0.1 6.6e-38 128.9 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain HTH_44 PF14641.6 KXG45727.1 - 4.5e-36 123.8 1.2 1e-35 122.6 1.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 KXG45727.1 - 6.6e-31 106.8 0.0 1.2e-30 105.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KXG45727.1 - 2.7e-27 95.4 0.0 6.5e-27 94.2 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 KXG45727.1 - 2.9e-16 59.8 17.8 2.9e-16 59.8 17.8 6.1 6 1 1 7 7 3 1 Acidic N-terminal SPT6 PH PF00169.29 KXG45727.1 - 1.1e-07 32.4 0.1 3.3e-07 30.8 0.1 2.0 1 0 0 1 1 1 1 PH domain HHH_9 PF17674.1 KXG45727.1 - 2.1e-07 31.7 2.5 3e-06 28.0 2.5 3.1 1 1 0 1 1 1 1 HHH domain SH2 PF00017.24 KXG45727.1 - 0.0002 21.4 0.0 0.00051 20.1 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 KXG45727.1 - 0.00061 20.0 0.0 0.0021 18.3 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif PH_11 PF15413.6 KXG45727.1 - 0.0096 16.3 0.9 0.23 11.9 0.9 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain Tex_N PF09371.10 KXG45727.1 - 0.011 15.4 8.9 0.094 12.4 0.0 4.1 4 0 0 4 4 4 0 Tex-like protein N-terminal domain GOLD_2 PF13897.6 KXG45727.1 - 0.06 13.9 3.5 1 9.9 0.0 3.3 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking ATP-synt_B PF00430.18 KXG45727.1 - 1.5 8.9 6.9 4.8 7.3 0.2 3.3 3 0 0 3 3 3 0 ATP synthase B/B' CF(0) Mod_r PF07200.13 KXG45727.1 - 5.3 7.1 8.4 5.5 7.1 0.5 3.4 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Pkinase PF00069.25 KXG45728.1 - 5.1e-65 219.5 0.0 6.4e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG45728.1 - 4.7e-36 124.4 0.0 6.3e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXG45728.1 - 7e-06 25.1 0.0 1.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXG45728.1 - 7.5e-05 22.2 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KXG45728.1 - 0.032 13.3 0.0 0.047 12.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KXG45728.1 - 0.057 13.3 0.0 0.19 11.6 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXG45728.1 - 0.063 12.2 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KXG45728.1 - 0.089 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family HUN PF08729.10 KXG45729.1 - 7.3e-08 32.3 0.1 1.6e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain RPAP1_C PF08620.10 KXG45730.1 - 1.5e-24 85.9 0.0 2.6e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KXG45730.1 - 8.7e-18 63.8 8.1 8.7e-18 63.8 8.1 2.0 2 0 0 2 2 2 1 RPAP1-like, N-terminal ANAPC1 PF12859.7 KXG45732.1 - 2.2e-31 109.1 2.4 2.8e-31 108.7 0.7 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KXG45732.1 - 0.0033 17.8 9.1 0.56 10.8 0.0 4.4 5 0 0 5 5 5 3 Proteasome/cyclosome repeat eIF2A PF08662.11 KXG45733.1 - 2.1e-80 269.2 0.0 1e-79 267.0 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KXG45733.1 - 0.00092 20.0 0.3 0.18 12.7 0.1 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF2126 PF09899.9 KXG45734.1 - 0.068 11.3 0.2 0.092 10.8 0.2 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Acetyltransf_13 PF13880.6 KXG45735.1 - 2.3e-21 75.5 0.0 5.2e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KXG45735.1 - 2.9e-14 52.6 0.3 5.5e-14 51.7 0.3 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO DAO_C PF16901.5 KXG45735.1 - 0.18 11.7 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase EMG1 PF03587.14 KXG45736.1 - 4.2e-80 268.0 0.1 4.9e-80 267.8 0.1 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyoxalase PF00903.25 KXG45737.1 - 0.006 16.8 0.3 0.024 14.8 0.0 2.1 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Gly-zipper_Omp PF13488.6 KXG45737.1 - 0.047 13.7 5.0 0.09 12.8 5.0 1.4 1 0 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.15 KXG45737.1 - 0.19 11.6 6.1 0.43 10.5 6.1 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.6 KXG45737.1 - 1 9.2 7.4 2 8.3 7.4 1.4 1 0 0 1 1 1 0 Glycine-zipper domain UQ_con PF00179.26 KXG45738.1 - 1.8e-52 176.7 0.0 2e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXG45738.1 - 0.0047 16.6 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXG45738.1 - 0.036 14.3 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KXG45738.1 - 0.045 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_N PF02771.16 KXG45739.1 - 7.3e-29 100.7 0.2 1.6e-28 99.6 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KXG45739.1 - 5.7e-25 88.3 1.4 1.1e-24 87.4 1.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXG45739.1 - 2.3e-16 59.8 0.0 4.4e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXG45739.1 - 1.3e-07 31.9 1.5 1.3e-07 31.9 1.5 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Zn_clus PF00172.18 KXG45740.1 - 1.2e-08 34.9 8.4 1.9e-08 34.3 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXG45740.1 - 0.0015 17.7 0.2 0.0029 16.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNase_J_C PF17770.1 KXG45740.1 - 0.15 13.1 0.1 4 8.6 0.0 3.0 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain PLU-1 PF08429.11 KXG45740.1 - 0.16 11.1 1.1 0.57 9.3 0.4 1.9 2 0 0 2 2 2 0 PLU-1-like protein XPG_N PF00752.17 KXG45741.1 - 2.2e-31 108.3 0.5 7.2e-31 106.7 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KXG45741.1 - 2.2e-31 108.0 1.1 8.6e-31 106.2 0.0 2.3 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 KXG45741.1 - 7.7e-05 23.2 0.3 0.0005 20.6 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 KXG45741.1 - 0.15 12.2 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif HXXSHH PF07586.11 KXG45741.1 - 6.6 6.2 7.7 1.4 8.4 4.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) Linker_histone PF00538.19 KXG45742.1 - 3.6e-31 107.4 0.5 3.6e-31 107.4 0.5 2.0 2 0 0 2 2 2 1 linker histone H1 and H5 family PIP5K PF01504.18 KXG45743.1 - 3.3e-102 341.4 0.1 3.3e-102 341.4 0.1 1.9 3 0 0 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase TFIID_20kDa PF03847.13 KXG45744.1 - 6.9e-21 74.5 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 KXG45744.1 - 0.0044 17.4 0.0 0.0044 17.4 0.0 3.2 4 1 0 4 4 4 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXG45744.1 - 0.066 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DASH_Spc34 PF08657.10 KXG45745.1 - 1.9e-43 149.1 2.6 5.1e-22 78.9 0.4 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 DASH_Spc19 PF08287.11 KXG45745.1 - 0.0023 17.9 0.2 0.0023 17.9 0.2 1.8 2 0 0 2 2 2 1 Spc19 ABC_tran_CTD PF16326.5 KXG45745.1 - 0.077 13.3 1.9 18 5.7 0.0 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF3381 PF11861.8 KXG45745.1 - 0.1 12.4 0.7 0.99 9.2 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Rpn3_C PF08375.11 KXG45746.1 - 5.4e-27 94.0 1.2 2e-26 92.2 1.2 2.0 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KXG45746.1 - 4.7e-19 68.8 0.1 1.5e-18 67.2 0.1 1.9 1 0 0 1 1 1 1 PCI domain ABATE PF07336.11 KXG45746.1 - 0.14 12.8 1.9 4.6 7.9 0.1 2.5 2 0 0 2 2 2 0 Putative stress-induced transcription regulator Sigma70_r1_2 PF00140.20 KXG45746.1 - 1.4 9.0 5.2 1 9.4 2.4 2.2 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 polyprenyl_synt PF00348.17 KXG45747.1 - 3e-72 242.8 0.0 5.5e-72 241.9 0.0 1.4 1 1 0 1 1 1 1 Polyprenyl synthetase ANTH PF07651.16 KXG45748.1 - 9.6e-79 264.2 0.0 9.6e-79 264.2 0.0 2.4 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KXG45748.1 - 4.9e-55 186.0 4.9 4.9e-55 186.0 4.9 5.6 3 2 2 5 5 5 1 I/LWEQ domain MMM1 PF10296.9 KXG45748.1 - 0.00048 19.3 0.0 0.00048 19.3 0.0 2.6 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 KXG45748.1 - 0.12 12.8 0.5 1.2 9.6 0.0 2.8 2 0 0 2 2 2 0 Pleckstrin homology domain HMG_box PF00505.19 KXG45749.1 - 1.1e-19 70.6 0.0 2e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXG45749.1 - 0.0019 18.8 0.0 0.0088 16.6 0.0 2.0 2 0 0 2 2 2 1 HMG-box domain K_channel_TID PF07941.11 KXG45749.1 - 1.1 9.8 3.3 1.9 9.0 3.3 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Exo_endo_phos PF03372.23 KXG45750.1 - 1.7e-11 44.1 0.0 3.3e-11 43.1 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KXG45750.1 - 2.9e-05 24.1 0.3 6.3e-05 23.0 0.3 1.6 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 KXG45750.1 - 0.0028 17.5 0.0 2.6 7.9 0.0 2.7 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase COX6A PF02046.15 KXG45751.1 - 1.9e-54 182.9 1.2 2.2e-54 182.7 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa PAPS_reduct PF01507.19 KXG45752.1 - 0.15 12.1 0.1 0.24 11.4 0.1 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family PARP PF00644.20 KXG45753.1 - 2.3e-09 37.1 0.0 4.8e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KXG45753.1 - 4.9e-07 29.5 0.0 1.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PRP4 PF08799.11 KXG45753.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Complex1_LYR PF05347.15 KXG45755.1 - 2e-12 46.9 3.0 2.3e-12 46.8 2.3 1.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXG45755.1 - 0.0002 22.1 1.2 0.00022 21.9 1.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like EGF PF00008.27 KXG45757.1 - 0.21 11.9 8.4 0.4 11.0 8.4 1.5 1 0 0 1 1 1 0 EGF-like domain ATP-sulfurylase PF01747.17 KXG45758.1 - 8.2e-86 286.9 0.0 1.2e-85 286.4 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KXG45758.1 - 3.4e-60 202.5 0.0 5.3e-60 201.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KXG45758.1 - 2e-51 173.8 0.0 3.5e-51 173.0 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_18 PF13238.6 KXG45758.1 - 0.042 14.4 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain SET PF00856.28 KXG45759.1 - 1.8e-11 44.7 0.2 1.8e-11 44.7 0.2 3.6 3 1 0 3 3 3 1 SET domain AWS PF17907.1 KXG45759.1 - 1.4e-08 34.6 8.9 1.4e-08 34.6 8.9 2.5 3 0 0 3 3 3 1 AWS domain DHHC PF01529.20 KXG45760.1 - 9.3e-35 119.7 8.2 9.3e-35 119.7 8.2 1.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase RHH_5 PF07878.11 KXG45761.1 - 0.062 13.2 0.1 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 B12D PF06522.11 KXG45761.1 - 0.073 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit PMT PF02366.18 KXG45762.1 - 4.4e-83 278.6 16.1 4.4e-83 278.6 16.1 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXG45762.1 - 2.4e-67 226.4 9.4 2.4e-67 226.4 9.4 2.7 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXG45762.1 - 1.4e-44 152.1 0.0 2.8e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 MIR domain PRP21_like_P PF12230.8 KXG45763.1 - 1.5e-55 188.4 9.9 5.1e-55 186.7 9.9 1.8 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KXG45763.1 - 2.9e-34 116.8 5.7 9.7e-17 60.7 0.5 2.7 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 KXG45763.1 - 0.014 15.0 2.6 0.048 13.3 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF5081 PF16887.5 KXG45763.1 - 0.39 9.8 3.7 0.64 9.1 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5081) Sec2p PF06428.11 KXG45764.1 - 4.3e-28 97.1 14.7 4.3e-28 97.1 14.7 1.9 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p SPATA1_C PF15743.5 KXG45764.1 - 1.5 8.9 18.1 0.031 14.3 7.0 2.2 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus GCN5L1 PF06320.13 KXG45764.1 - 3.4 7.8 11.4 0.96 9.6 6.7 2.1 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) dsDNA_bind PF01984.20 KXG45765.1 - 9.4e-40 135.4 11.2 1.1e-39 135.2 11.2 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.6 KXG45765.1 - 0.017 15.7 0.9 0.025 15.2 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) Coq4 PF05019.13 KXG45766.1 - 1.6e-96 321.9 0.0 2e-96 321.6 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DUF5345 PF17280.2 KXG45766.1 - 2.1 8.4 4.4 3.5 7.7 4.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5345) SET PF00856.28 KXG45767.1 - 1.2e-19 71.3 0.0 2.8e-19 70.1 0.0 1.6 2 0 0 2 2 2 1 SET domain ApbA_C PF08546.11 KXG45768.1 - 6.7e-33 113.6 0.0 1e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KXG45768.1 - 2.5e-24 85.7 0.0 6.8e-24 84.3 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KXG45768.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 ThiF family Sas10_Utp3 PF04000.15 KXG45769.1 - 2.5e-17 63.3 1.0 2.5e-17 63.3 1.0 2.2 2 1 0 2 2 2 1 Sas10/Utp3/C1D family DUF2076 PF09849.9 KXG45770.1 - 5.4e-09 36.5 15.3 6.6e-09 36.2 15.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KXG45770.1 - 4e-05 23.6 0.9 6.5e-05 23.0 0.9 1.4 1 0 0 1 1 1 1 CHCH domain TFIIA PF03153.13 KXG45770.1 - 1.3 9.0 9.5 1.4 8.8 9.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UBX PF00789.20 KXG45771.1 - 8.9e-10 38.6 0.0 1.9e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain SURF1 PF02104.15 KXG45772.1 - 1.3e-47 162.3 0.0 1.9e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T_C PF15511.6 KXG45773.1 - 2e-45 153.3 0.0 3.1e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXG45773.1 - 1.1e-07 32.1 0.1 1.9e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KXG45773.1 - 0.089 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 YL1 PF05764.13 KXG45773.1 - 3.6 7.6 7.0 0.9 9.6 3.3 1.9 1 1 0 2 2 2 0 YL1 nuclear protein CMS1 PF14617.6 KXG45774.1 - 1.1e-76 257.5 4.3 1.5e-76 257.1 4.3 1.2 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KXG45774.1 - 0.00038 20.3 0.0 0.00066 19.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RNA12 PF10443.9 KXG45774.1 - 0.3 9.8 3.3 0.41 9.3 3.3 1.1 1 0 0 1 1 1 0 RNA12 protein PGA2 PF07543.12 KXG45774.1 - 8.6 6.3 12.2 3.3 7.7 9.6 1.6 2 0 0 2 2 2 0 Protein trafficking PGA2 RRM_1 PF00076.22 KXG45775.1 - 4e-12 45.8 0.0 8.2e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WTX PF09422.10 KXG45775.1 - 2.3 7.2 37.6 0.29 10.2 31.0 2.1 2 0 0 2 2 2 0 WTX protein Ras PF00071.22 KXG45776.1 - 4.2e-55 185.8 0.0 4.9e-55 185.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXG45776.1 - 4.3e-21 75.3 0.0 6.5e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG45776.1 - 6.6e-08 32.2 0.0 8.6e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RhoGAP PF00620.27 KXG45777.1 - 1.3e-48 164.6 0.0 3.2e-48 163.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KXG45777.1 - 2.4e-11 43.7 0.8 6.1e-11 42.4 0.1 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Fungal_trans PF04082.18 KXG45777.1 - 1.7e-05 24.0 0.1 3.4e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain V-ATPase_G_2 PF16999.5 KXG45777.1 - 1.2 9.6 11.6 1.5 9.3 2.7 2.8 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit OmpH PF03938.14 KXG45777.1 - 2.3 8.5 5.2 7.7 6.9 5.2 2.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 KXG45777.1 - 5.6 5.9 6.7 10 5.1 6.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 KXG45777.1 - 6.5 6.0 6.6 12 5.1 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MBA1 PF07961.11 KXG45778.1 - 6.8e-06 25.3 0.0 9.2e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.15 KXG45778.1 - 0.0036 17.4 0.2 0.0069 16.5 0.2 1.5 1 1 0 1 1 1 1 Tim44-like domain EOS1 PF12326.8 KXG45779.1 - 0.0039 17.2 7.0 0.0069 16.3 2.3 2.2 1 1 1 2 2 2 2 N-glycosylation protein SUI1 PF01253.22 KXG45780.1 - 6.5e-28 97.1 3.4 9e-28 96.6 3.4 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 UPF0139 PF03669.13 KXG45780.1 - 3.8e-07 29.9 0.3 6.9e-07 29.1 0.3 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Med12 PF09497.10 KXG45781.1 - 7.2e-27 93.5 0.5 1.9e-26 92.2 0.5 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 RRM_1 PF00076.22 KXG45782.1 - 4.7e-10 39.2 0.0 4.1e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CIA30 PF08547.12 KXG45783.1 - 7.2e-39 133.4 0.2 5.1e-24 85.1 0.1 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Cation_ATPase_N PF00690.26 KXG45783.1 - 0.04 13.6 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus SAICAR_synt PF01259.18 KXG45784.1 - 1.3e-96 323.0 0.0 1.7e-96 322.7 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase ANAPC5 PF12862.7 KXG45785.1 - 6.7e-32 109.4 6.2 2e-31 107.9 6.2 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 KXG45785.1 - 0.0041 17.6 1.9 2.3 8.8 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXG45785.1 - 0.028 14.7 8.2 6.1 7.2 0.6 5.3 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXG45785.1 - 0.043 13.9 3.1 66 4.0 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXG45785.1 - 1.5 8.8 3.5 16 5.5 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Mid2 PF04478.12 KXG45786.1 - 0.00014 21.7 0.1 0.0004 20.2 0.0 1.8 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor HemeBinding_Shp PF11545.8 KXG45786.1 - 0.0033 17.4 0.1 0.0053 16.8 0.1 1.3 1 0 0 1 1 1 1 Cell surface heme-binding protein Shp Mucin PF01456.17 KXG45786.1 - 0.012 15.6 2.2 0.019 14.9 2.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SKG6 PF08693.10 KXG45786.1 - 0.016 14.6 0.6 0.042 13.3 0.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.11 KXG45786.1 - 0.065 13.3 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Podoplanin Zn_clus PF00172.18 KXG45787.1 - 2.3e-08 34.0 10.9 4.1e-08 33.2 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ring_hydroxyl_A PF00848.19 KXG45788.1 - 1.6e-27 96.9 6.7 7.5e-15 55.5 0.6 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) DIPSY PF11763.8 KXG45788.1 - 0.051 13.7 0.6 0.2 11.9 0.0 2.2 2 1 1 3 3 3 0 Cell-wall adhesin ligand-binding C-terminal CorC_HlyC PF03471.17 KXG45788.1 - 0.099 12.7 0.0 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 Transporter associated domain Glyco_tranf_2_3 PF13641.6 KXG45789.1 - 5.3e-22 78.8 0.0 7.5e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KXG45789.1 - 2.3e-19 70.1 0.7 2.3e-19 70.1 0.7 2.9 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 KXG45789.1 - 6.9e-14 51.3 0.9 9e-09 34.4 0.4 2.4 1 1 1 2 2 2 2 Cellulose synthase Glycos_transf_2 PF00535.26 KXG45789.1 - 1e-13 51.5 0.0 1.6e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KXG45789.1 - 7.1e-13 48.4 0.0 1.2e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_12 PF01670.16 KXG45790.1 - 9.4e-17 61.7 3.6 1.7e-16 60.9 3.6 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 MFS_1 PF07690.16 KXG45791.1 - 2.2e-28 99.2 25.6 3.2e-27 95.4 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5336 PF17270.2 KXG45791.1 - 0.0086 15.7 0.1 1.8 8.1 0.0 2.6 2 0 0 2 2 2 2 Family of unknown function (DUF5336) MFS_1 PF07690.16 KXG45792.1 - 2.7e-20 72.6 33.5 2.7e-20 72.6 33.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXG45792.1 - 7.7e-08 32.2 6.4 7.7e-08 32.2 6.4 2.8 3 2 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF2406 PF10295.9 KXG45793.1 - 3.2e-25 88.6 0.5 1.1e-24 86.8 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) DUF1908 PF08926.11 KXG45793.1 - 0.0077 15.3 0.8 0.014 14.5 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1908) DUF3602 PF12223.8 KXG45794.1 - 5.7e-20 71.7 3.0 7.5e-13 48.9 0.3 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Mito_carr PF00153.27 KXG45795.1 - 3.4e-44 148.7 7.5 7.8e-17 61.0 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.28 KXG45796.1 - 9.4e-06 26.0 0.0 1.5 9.3 0.0 3.2 2 1 0 2 2 2 2 CBS domain VMA21 PF09446.10 KXG45797.1 - 2.3e-15 56.4 7.6 3.4e-15 55.9 7.6 1.3 1 0 0 1 1 1 1 VMA21-like domain ABC_membrane PF00664.23 KXG45797.1 - 0.024 14.3 0.0 0.03 14.0 0.0 1.0 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF2705 PF10920.8 KXG45797.1 - 0.047 13.0 0.1 0.056 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2705) SNF2_N PF00176.23 KXG45798.1 - 1.2e-55 188.6 0.7 1.9e-55 188.0 0.7 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXG45798.1 - 1.3e-20 73.8 0.8 4.7e-19 68.8 0.1 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG45798.1 - 7.2e-10 39.1 0.0 1.8e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXG45798.1 - 3.2e-06 26.6 0.1 1.2e-05 24.7 0.1 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 KXG45798.1 - 3.1e-05 23.8 0.0 6.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HIGH_NTase1_ass PF16581.5 KXG45798.1 - 0.0072 16.3 0.0 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 Cytidyltransferase-related C-terminal region HHH_3 PF12836.7 KXG45798.1 - 0.066 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif TPR_19 PF14559.6 KXG45798.1 - 0.093 13.2 0.0 0.44 11.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Dus PF01207.17 KXG45799.1 - 1.7e-41 142.3 0.0 5.6e-41 140.6 0.0 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Pyrophosphatase PF00719.19 KXG45800.1 - 4e-58 195.7 0.2 5.2e-58 195.4 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.9 KXG45801.1 - 1.6e-18 66.6 0.1 2.2e-18 66.2 0.1 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.13 KXG45802.1 - 8.8e-15 54.4 0.7 8.8e-15 54.4 0.7 2.0 2 0 0 2 2 2 1 Sec20 Rep_fac_C PF08542.11 KXG45803.1 - 3.1e-19 69.1 0.0 7.4e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KXG45803.1 - 4.2e-15 56.3 0.0 1.6e-14 54.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KXG45803.1 - 4e-12 46.2 0.0 1.5e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 KXG45803.1 - 4.7e-09 36.4 0.0 1.1e-08 35.2 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 KXG45803.1 - 7.7e-06 25.7 0.0 6.9e-05 22.6 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXG45803.1 - 2.9e-05 24.5 0.1 0.0012 19.3 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 KXG45803.1 - 0.00011 22.1 0.0 0.0003 20.7 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 KXG45803.1 - 0.00015 22.0 0.0 0.00062 20.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KXG45803.1 - 0.00022 21.5 0.0 0.00064 20.0 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain Mg_chelatase PF01078.21 KXG45803.1 - 0.00023 20.6 0.0 0.013 14.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 KXG45803.1 - 0.0024 17.7 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_24 PF13479.6 KXG45803.1 - 0.0033 17.2 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXG45803.1 - 0.004 17.2 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KXG45803.1 - 0.007 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 KXG45803.1 - 0.0072 16.3 0.0 0.041 13.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KXG45803.1 - 0.012 16.0 0.1 0.07 13.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXG45803.1 - 0.015 14.8 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KXG45803.1 - 0.017 14.3 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF4863 PF16155.5 KXG45803.1 - 0.029 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4863) ResIII PF04851.15 KXG45803.1 - 0.066 13.2 0.0 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KXG45803.1 - 0.068 12.9 0.0 0.26 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXG45803.1 - 0.071 13.7 0.0 0.22 12.1 0.0 1.9 2 1 0 2 2 1 0 AAA domain AAA_28 PF13521.6 KXG45803.1 - 0.096 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KXG45803.1 - 0.11 13.0 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1409 PF07197.12 KXG45803.1 - 0.12 12.3 0.4 0.64 9.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) TPM_phosphatase PF04536.14 KXG45803.1 - 0.15 12.2 0.0 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 TPM domain AAA_3 PF07726.11 KXG45803.1 - 0.16 11.8 0.0 2.9 7.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Hydrolase_6 PF13344.6 KXG45804.1 - 3.1e-30 104.2 0.0 6.7e-30 103.2 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXG45804.1 - 2e-14 53.4 0.0 1.9e-13 50.3 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KXG45804.1 - 1.2e-10 42.0 0.0 2.2e-08 34.6 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXG45804.1 - 5.1e-06 26.7 0.0 0.12 12.5 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KXG45804.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) LAGLIDADG_3 PF14528.6 KXG45804.1 - 0.2 12.0 1.2 0.29 11.5 0.1 1.9 2 0 0 2 2 2 0 LAGLIDADG-like domain Fungal_trans_2 PF11951.8 KXG45805.1 - 1.4e-18 66.9 2.5 6.8e-17 61.3 2.5 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 KXG45806.1 - 6e-08 32.8 0.0 1.6e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXG45806.1 - 1.4e-07 31.3 0.0 1.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 KXG45806.1 - 0.0031 17.6 0.0 0.0047 17.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KXG45806.1 - 0.043 14.3 0.0 0.076 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 KXG45806.1 - 0.092 13.3 0.0 0.3 11.7 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NUDIX PF00293.28 KXG45808.1 - 1.6e-09 37.9 0.0 2.1e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain LETM1 PF07766.13 KXG45809.1 - 2.8e-101 338.4 0.1 4.9e-101 337.6 0.1 1.4 1 0 0 1 1 1 1 LETM1-like protein DUF2838 PF10998.8 KXG45810.1 - 3.2e-43 146.5 11.5 3.2e-43 146.5 11.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Atg14 PF10186.9 KXG45810.1 - 0.015 14.4 3.5 0.028 13.5 3.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2841 PF11001.8 KXG45811.1 - 1e-47 161.2 0.0 1.7e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Glyco_hydro_62 PF03664.13 KXG45812.1 - 4.3e-156 518.2 13.3 5e-156 518.0 13.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 DUF1525 PF07511.11 KXG45812.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) Glyco_hydro_10 PF00331.20 KXG45813.1 - 1.2e-93 313.8 0.4 1.4e-73 247.8 0.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 Lipase_3 PF01764.25 KXG45814.1 - 2.3e-35 121.5 0.0 3.3e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 KXG45814.1 - 0.005 16.4 0.6 0.073 12.6 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Thioesterase PF00975.20 KXG45814.1 - 0.0054 16.9 0.0 0.0077 16.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 KXG45814.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 KXG45814.1 - 0.041 13.5 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_8 PF06259.12 KXG45814.1 - 0.042 13.5 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_3 PF07859.13 KXG45814.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.22 KXG45814.1 - 0.75 9.7 5.6 0.45 10.5 3.2 1.8 2 1 0 2 2 2 0 Cutinase TFIIA PF03153.13 KXG45815.1 - 7.5 6.4 20.9 11 5.9 20.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DAAD PF18752.1 KXG45815.1 - 7.8 6.2 11.8 14 5.4 11.8 1.5 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase SMC_N PF02463.19 KXG45816.1 - 2.4e-49 167.7 33.9 1.6e-47 161.8 33.9 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXG45816.1 - 1.4e-30 106.0 0.1 6.1e-30 103.9 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXG45816.1 - 4.5e-08 33.3 24.0 3.9e-05 23.6 0.0 4.9 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXG45816.1 - 8.4e-08 31.8 0.0 1.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KXG45816.1 - 9.7e-07 28.8 16.2 9.7e-07 28.8 16.2 4.3 3 1 1 4 4 4 1 AAA ATPase domain SbcCD_C PF13558.6 KXG45816.1 - 0.0046 17.2 0.0 0.025 14.8 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SlyX PF04102.12 KXG45816.1 - 0.59 10.8 49.6 1.4 9.6 0.5 8.3 5 3 2 7 7 7 0 SlyX Spc7 PF08317.11 KXG45816.1 - 0.61 8.9 116.6 0.017 14.0 12.6 7.1 3 2 4 7 7 7 0 Spc7 kinetochore protein ABC_tran PF00005.27 KXG45816.1 - 1.3 9.5 0.0 1.3 9.5 0.0 6.5 4 2 0 4 4 4 0 ABC transporter CcmD PF04995.14 KXG45817.1 - 0.043 13.9 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) E3_binding PF02817.17 KXG45818.1 - 5.1e-11 42.7 0.8 2.6e-10 40.5 0.2 2.2 2 0 0 2 2 2 1 e3 binding domain Rab15_effector PF15208.6 KXG45818.1 - 0.22 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Rab15 effector WD40 PF00400.32 KXG45819.1 - 4.3e-26 90.7 14.1 3.1e-05 24.6 0.0 6.7 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG45819.1 - 4.4e-14 52.6 5.8 0.00032 21.0 0.2 4.5 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXG45819.1 - 1.3e-08 35.0 0.1 0.0036 17.2 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXG45819.1 - 0.098 11.6 0.0 0.43 9.5 0.0 1.9 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_M18 PF02127.15 KXG45820.1 - 5.2e-170 565.9 0.0 5.9e-170 565.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) DUF1746 PF08508.10 KXG45821.1 - 2.9e-38 130.8 1.6 3.9e-38 130.3 1.6 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CLP_protease PF00574.23 KXG45822.1 - 2.1e-74 249.3 0.0 2.7e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Clp protease Tugs PF17840.1 KXG45822.1 - 0.15 12.3 1.0 0.35 11.1 1.0 1.6 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain adh_short PF00106.25 KXG45824.1 - 6.6e-25 87.7 0.1 2.3e-19 69.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXG45824.1 - 2.3e-10 40.5 0.1 4.9e-09 36.1 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG45824.1 - 1.6e-09 38.0 0.1 3.1e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXG45824.1 - 0.001 18.3 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXG45824.1 - 0.087 12.3 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.13 KXG45824.1 - 0.11 12.4 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family SLT PF01464.20 KXG45825.1 - 0.0033 17.1 1.7 0.013 15.1 1.7 2.0 1 1 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.6 KXG45825.1 - 0.22 11.2 3.0 0.47 10.2 3.0 1.6 1 1 0 1 1 1 0 Lysozyme-like SOG2 PF10428.9 KXG45825.1 - 5.6 6.1 10.7 6.5 5.8 10.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein AA_permease_2 PF13520.6 KXG45826.1 - 1.2e-63 215.4 47.9 1.5e-63 215.1 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG45826.1 - 1.5e-23 83.2 38.3 2.1e-23 82.7 38.3 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 KXG45826.1 - 0.019 14.9 0.0 0.019 14.9 0.0 3.5 3 0 0 3 3 3 0 LPXTG cell wall anchor motif DPM3 PF08285.11 KXG45826.1 - 0.22 11.7 0.1 0.22 11.7 0.1 4.3 5 1 1 6 6 6 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Glyco_hydro_38N PF01074.22 KXG45828.1 - 2.3e-87 293.0 1.4 2.3e-87 293.0 1.4 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KXG45828.1 - 1.1e-57 195.5 0.1 8.3e-57 192.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KXG45828.1 - 5.7e-27 93.7 0.0 1.1e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KXG45828.1 - 1.1e-09 38.2 0.0 2.6e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 KXG45828.1 - 0.07 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 7TMR-DISMED2 PF07696.11 KXG45828.1 - 0.084 12.9 0.1 0.88 9.6 0.0 2.5 2 0 0 2 2 2 0 7TMR-DISM extracellular 2 NuA4 PF09340.10 KXG45829.1 - 1.4e-27 95.4 0.5 1.4e-27 95.4 0.5 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Ctr PF04145.15 KXG45830.1 - 1.7e-29 103.3 1.3 2.1e-29 103.0 1.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Cupin_8 PF13621.6 KXG45831.1 - 5.3e-15 55.8 0.0 1.6e-13 50.9 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KXG45831.1 - 2.6e-10 40.7 0.0 2.1e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 KXG45831.1 - 1.7e-07 31.0 0.0 3.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXG45831.1 - 0.0072 16.2 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain DEAD PF00270.29 KXG45832.1 - 2.7e-44 151.0 0.8 5e-44 150.1 0.8 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG45832.1 - 1.6e-31 108.9 0.1 1.2e-30 106.1 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG45832.1 - 3.3e-05 24.0 0.0 5.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KXG45832.1 - 0.00021 21.1 0.1 0.0004 20.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXG45832.1 - 0.00083 19.7 0.6 0.0048 17.2 0.4 2.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXG45832.1 - 0.005 17.1 0.5 0.028 14.7 0.5 2.2 1 1 0 1 1 1 1 AAA domain IL17R_D_N PF16742.5 KXG45832.1 - 0.045 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D CMS1 PF14617.6 KXG45832.1 - 0.068 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit FAA_hydrolase PF01557.18 KXG45833.1 - 4.5e-53 180.2 0.0 5.1e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family YlqD PF11068.8 KXG45833.1 - 0.086 13.2 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 YlqD protein Cytochrom_C552 PF02335.15 KXG45834.1 - 0.064 12.2 0.1 0.064 12.2 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c552 UDPGT PF00201.18 KXG45835.1 - 6.2e-08 31.9 0.0 8.6e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UnbV_ASPIC PF07593.12 KXG45835.1 - 0.076 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 ASPIC and UnbV FMN_dh PF01070.18 KXG45836.1 - 3.5e-111 371.6 0.0 4.2e-111 371.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXG45836.1 - 1.2e-17 63.8 0.1 2.7e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KXG45836.1 - 0.0013 17.8 0.0 0.0029 16.7 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXG45836.1 - 0.0026 17.2 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 KXG45836.1 - 0.0065 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase Ribosomal_L31e PF01198.19 KXG45836.1 - 0.17 12.2 0.0 0.45 10.8 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L31e p450 PF00067.22 KXG45837.1 - 4.5e-59 200.4 0.0 5.5e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amino_oxidase PF01593.24 KXG45838.1 - 5.5e-34 118.2 0.0 1.7e-33 116.6 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXG45838.1 - 2.7e-10 40.3 0.0 1.6e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXG45838.1 - 0.029 13.6 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KXG45838.1 - 0.2 10.9 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 KXG45839.1 - 7.6e-36 123.8 0.0 2.3e-35 122.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Sec16_N PF12935.7 KXG45839.1 - 0.037 14.2 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus DIOX_N PF14226.6 KXG45840.1 - 3.3e-23 82.7 0.0 6.6e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG45840.1 - 3.7e-14 53.0 0.0 7.3e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 KXG45841.1 - 0 1096.6 0.0 1.6e-71 241.2 0.0 5.1 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.20 KXG45841.1 - 1.6e-186 620.4 0.0 3e-41 141.6 0.0 5.5 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.25 KXG45841.1 - 1.4e-49 166.3 14.4 4.6e-11 42.9 0.3 6.4 6 0 0 6 6 6 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXG45841.1 - 1.2e-10 42.2 0.0 0.085 13.8 0.0 5.6 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain LIFR_D2 PF17971.1 KXG45841.1 - 0.1 12.8 0.3 0.64 10.2 0.1 2.5 3 0 0 3 3 3 0 Leukemia inhibitory factor receptor D2 domain Peptidase_M54 PF07998.11 KXG45842.1 - 3e-07 30.6 0.0 6.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M54 Reprolysin_4 PF13583.6 KXG45842.1 - 0.13 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 KXG45842.1 - 0.18 10.3 0.4 0.31 9.6 0.4 1.2 1 0 0 1 1 1 0 Putative peptidase family PWI PF01480.17 KXG45844.1 - 7.4e-30 103.1 0.0 1.6e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 PWI domain DUF2951 PF11166.8 KXG45844.1 - 0.11 12.7 4.2 2.6 8.3 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Borrelia_P83 PF05262.11 KXG45844.1 - 6.1 5.2 11.9 2.1 6.7 0.5 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein DUF3430 PF11912.8 KXG45845.1 - 0.01 15.9 0.2 0.012 15.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Pkinase PF00069.25 KXG45846.1 - 2.5e-46 158.2 0.0 3.8e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG45846.1 - 5.4e-16 58.6 0.0 8.4e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KXG45846.1 - 0.0037 16.9 0.1 0.007 16.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KXG45846.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KXG45846.1 - 0.015 15.3 0.1 0.19 11.6 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXG45846.1 - 0.033 13.0 0.5 0.074 11.8 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 KXG45846.1 - 0.034 13.5 0.1 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S8e PF01201.22 KXG45847.1 - 1.8e-45 154.4 3.8 2.7e-45 153.9 3.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e RIBIOP_C PF04950.12 KXG45847.1 - 0.62 9.4 8.6 1.5 8.2 8.6 1.5 1 1 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Ribosomal_L21p PF00829.21 KXG45848.1 - 9.7e-09 35.4 0.0 1.5e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein RIB43A PF05914.12 KXG45848.1 - 0.089 11.5 0.5 0.14 10.9 0.5 1.2 1 0 0 1 1 1 0 RIB43A GMC_oxred_N PF00732.19 KXG45849.1 - 6.7e-53 180.0 0.0 1.2e-52 179.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG45849.1 - 2.3e-34 119.0 0.0 4.3e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXG45849.1 - 8.3e-08 31.7 0.2 0.0017 17.5 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXG45849.1 - 2.3e-06 27.5 0.3 1.3e-05 25.0 0.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXG45849.1 - 0.00016 21.1 0.5 0.14 11.4 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXG45849.1 - 0.00056 19.1 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXG45849.1 - 0.00056 20.1 0.8 0.0029 17.8 0.1 2.6 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG45849.1 - 0.0012 18.2 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG45849.1 - 0.0013 18.0 0.3 0.0023 17.2 0.3 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KXG45849.1 - 0.066 11.9 0.3 0.13 11.0 0.3 1.5 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 KXG45849.1 - 0.12 12.4 0.2 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding DFF-C PF09033.10 KXG45851.1 - 0.035 14.0 0.1 0.066 13.1 0.1 1.4 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain Metal_resist PF13801.6 KXG45851.1 - 0.078 13.2 2.9 0.21 11.8 2.9 1.8 1 0 0 1 1 1 0 Heavy-metal resistance LMBR1 PF04791.16 KXG45851.1 - 1.4 7.7 6.5 7.5 5.3 0.0 2.1 1 1 1 2 2 2 0 LMBR1-like membrane protein Pyr_redox_3 PF13738.6 KXG45852.1 - 1.3e-06 27.9 1.5 0.0028 17.0 1.9 3.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG45852.1 - 4.9e-06 26.7 0.2 3.1e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KXG45852.1 - 9e-06 24.4 0.0 0.00021 19.9 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXG45852.1 - 1.5e-05 24.4 0.0 0.0058 15.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXG45852.1 - 2.8e-05 24.2 0.0 0.0027 17.8 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KXG45852.1 - 0.013 15.4 0.2 2.8 7.9 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding ThiF PF00899.21 KXG45852.1 - 0.048 13.0 0.9 5.8 6.2 0.0 3.0 3 0 0 3 3 3 0 ThiF family K_oxygenase PF13434.6 KXG45852.1 - 0.17 11.0 0.0 1.1 8.3 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) ADH_N PF08240.12 KXG45853.1 - 9.5e-22 77.0 3.8 2.6e-20 72.3 1.0 2.8 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG45853.1 - 6.3e-20 71.5 0.2 9.8e-20 70.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG45853.1 - 3.7e-08 34.5 0.0 7.1e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXG45853.1 - 0.0011 18.3 1.7 0.0019 17.6 1.7 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PDH PF02153.17 KXG45853.1 - 0.051 12.6 0.1 0.29 10.1 0.0 2.0 2 0 0 2 2 2 0 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.19 KXG45853.1 - 0.07 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXG45853.1 - 0.11 12.1 0.6 0.2 11.2 0.6 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CoA_binding PF02629.19 KXG45853.1 - 0.29 11.8 2.0 0.38 11.5 0.7 1.9 2 0 0 2 2 2 0 CoA binding domain Fungal_trans PF04082.18 KXG45854.1 - 2.1e-19 69.6 0.2 3.8e-19 68.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG45854.1 - 0.0013 18.8 6.6 0.0031 17.6 6.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb4 PF03874.16 KXG45855.1 - 5.9e-26 91.2 2.1 7.9e-26 90.8 2.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Cut8 PF08559.10 KXG45855.1 - 0.0025 17.5 0.6 0.003 17.2 0.6 1.2 1 1 0 1 1 1 1 Cut8, nuclear proteasome tether protein Met_10 PF02475.16 KXG45856.1 - 4.3e-67 225.7 0.0 6e-67 225.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 KXG45856.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase zf-GRF PF06839.12 KXG45857.1 - 8.3e-08 32.2 6.4 1.6e-07 31.3 6.4 1.5 1 0 0 1 1 1 1 GRF zinc finger Ank_2 PF12796.7 KXG45858.1 - 2.7e-56 188.1 0.0 1.9e-13 50.8 0.0 5.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG45858.1 - 4.2e-37 121.9 0.1 0.00012 22.3 0.1 10.4 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.6 KXG45858.1 - 2.2e-36 123.8 0.0 1e-07 32.4 0.0 7.2 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG45858.1 - 4.6e-35 119.2 4.0 1.6e-09 37.8 0.0 8.0 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KXG45858.1 - 1.2e-34 117.2 3.1 6.1e-05 23.3 0.2 10.4 10 1 0 10 10 10 8 Ankyrin repeat DUF3818 PF12825.7 KXG45859.1 - 1.1e-130 435.6 2.8 1.7e-130 435.0 2.8 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KXG45859.1 - 9.6e-38 129.1 0.3 1.7e-37 128.3 0.3 1.4 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KXG45859.1 - 8.3e-15 54.8 0.4 3.3e-14 52.8 0.1 2.2 2 0 0 2 2 2 1 PX domain zf-C2H2 PF00096.26 KXG45860.1 - 0.00014 22.1 2.5 0.00014 22.1 2.5 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXG45860.1 - 0.56 10.7 19.3 5.5 7.6 3.2 3.7 3 0 0 3 3 3 0 Zinc-finger double domain DUF3432 PF11914.8 KXG45860.1 - 7.2 6.9 14.2 1.2 9.5 9.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) AAA PF00004.29 KXG45861.1 - 1.5e-47 161.3 0.0 5.4e-43 146.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXG45861.1 - 3e-05 23.7 8.6 9.4e-05 22.1 0.1 3.5 3 1 0 3 3 3 1 AAA+ lid domain AAA_16 PF13191.6 KXG45861.1 - 7.5e-05 23.2 0.0 0.021 15.2 0.0 3.3 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXG45861.1 - 0.00016 21.5 0.0 0.00043 20.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 KXG45861.1 - 0.00058 19.0 0.0 0.00096 18.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.6 KXG45861.1 - 0.0028 17.9 0.0 0.046 14.0 0.0 3.0 3 1 1 4 4 3 1 AAA domain AAA_2 PF07724.14 KXG45861.1 - 0.0034 17.5 0.0 0.0097 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KXG45861.1 - 0.0044 17.4 0.0 0.015 15.7 0.0 2.0 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 KXG45861.1 - 0.007 15.6 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 KXG45861.1 - 0.0075 15.9 0.2 0.04 13.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXG45861.1 - 0.0091 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KXG45861.1 - 0.016 14.7 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KXG45861.1 - 0.029 13.8 0.1 0.055 12.9 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXG45861.1 - 0.039 14.0 0.0 0.13 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 KXG45861.1 - 0.041 13.2 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 KXG45861.1 - 0.052 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXG45861.1 - 0.061 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KXG45861.1 - 0.071 13.3 0.2 0.45 10.7 0.0 2.5 3 0 0 3 3 2 0 AAA domain PhoH PF02562.16 KXG45861.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KXG45861.1 - 0.11 12.8 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 KXG45861.1 - 0.15 12.1 0.1 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain F-box PF00646.33 KXG45862.1 - 0.00018 21.3 0.0 0.00045 20.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain HTH_29 PF13551.6 KXG45862.1 - 0.13 12.3 0.0 0.94 9.6 0.0 2.4 3 0 0 3 3 3 0 Winged helix-turn helix AA_permease_2 PF13520.6 KXG45863.1 - 4.4e-55 187.2 50.8 5.3e-55 187.0 50.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG45863.1 - 4.8e-15 55.1 41.8 6.6e-15 54.7 41.8 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 KXG45863.1 - 0.6 10.1 0.0 0.6 10.1 0.0 2.6 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Questin_oxidase PF14027.6 KXG45864.1 - 5.7e-74 249.7 0.1 6.7e-74 249.4 0.1 1.0 1 0 0 1 1 1 1 Questin oxidase-like HECT_2 PF09814.9 KXG45865.1 - 1.4e-108 363.1 0.1 1.7e-108 362.9 0.1 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 KXG45865.1 - 0.052 13.8 3.2 0.29 11.4 3.1 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TauD PF02668.16 KXG45866.1 - 1.9e-58 198.4 1.1 2.3e-58 198.1 1.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KXG45867.1 - 1.3e-24 86.8 20.5 1.3e-24 86.8 20.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4500 PF14937.6 KXG45867.1 - 0.0037 17.3 0.1 0.0098 15.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4500) DUF3446 PF11928.8 KXG45867.1 - 0.076 13.3 0.2 0.58 10.5 0.2 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain Herpes_teg_N PF04843.12 KXG45867.1 - 0.19 11.4 0.2 10 5.8 0.1 2.3 2 0 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region Cupin_2 PF07883.11 KXG45868.1 - 0.021 14.5 0.2 0.043 13.5 0.2 1.5 1 1 0 1 1 1 0 Cupin domain PI-PLC-X PF00388.19 KXG45869.1 - 2.9e-57 192.3 0.0 5e-57 191.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KXG45869.1 - 1.4e-38 131.7 0.7 2.4e-38 131.0 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain MID_MedPIWI PF18296.1 KXG45869.1 - 0.22 11.3 2.7 0.42 10.4 2.7 1.4 1 0 0 1 1 1 0 MID domain of medPIWI GST_N_3 PF13417.6 KXG45870.1 - 7.2e-07 29.5 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXG45870.1 - 0.00014 22.1 0.0 0.00023 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXG45870.1 - 0.00016 21.6 0.1 0.00027 20.9 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXG45870.1 - 0.0044 17.2 0.0 0.0076 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXG45870.1 - 0.049 13.9 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribosomal_L37 PF08561.10 KXG45871.1 - 2.9e-41 140.7 0.6 3.8e-41 140.4 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Epimerase PF01370.21 KXG45872.1 - 2.7e-35 122.0 0.0 2.6e-34 118.8 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG45872.1 - 3.6e-35 121.9 0.0 1.3e-34 120.2 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXG45872.1 - 4.9e-08 32.5 0.0 5.3e-06 25.8 0.0 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KXG45872.1 - 9.8e-07 28.2 0.0 0.0003 20.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KXG45872.1 - 2e-05 23.8 0.0 0.00024 20.2 0.0 2.5 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KXG45872.1 - 0.0071 15.8 0.1 0.034 13.6 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KXG45872.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.17 KXG45872.1 - 0.026 13.6 0.0 0.23 10.5 0.0 2.4 1 1 0 1 1 1 0 RmlD substrate binding domain Pyr_redox_2 PF07992.14 KXG45872.1 - 0.045 13.0 0.0 0.07 12.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 KXG45872.1 - 0.18 12.1 0.1 1.2 9.4 0.0 2.2 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Spherulin4 PF12138.8 KXG45873.1 - 2.7e-74 249.8 0.4 3.2e-74 249.6 0.4 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 OppC_N PF12911.7 KXG45873.1 - 0.096 12.7 0.8 0.2 11.7 0.8 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Glyco_hydro_114 PF03537.13 KXG45874.1 - 5.8e-87 290.8 3.4 7e-87 290.6 3.4 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Tissue_fac PF01108.17 KXG45875.1 - 0.0086 15.9 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Tissue factor Glyco_trans_1_4 PF13692.6 KXG45876.1 - 5.4e-11 43.1 0.0 1.2e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KXG45876.1 - 6.5e-11 42.1 0.0 1.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 KXG45876.1 - 0.07 12.9 0.0 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) DPPIV_N PF00930.21 KXG45877.1 - 6.9e-115 383.6 0.0 1.3e-114 382.7 0.0 1.4 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KXG45877.1 - 6.3e-48 163.1 1.4 9.9e-48 162.4 1.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KXG45877.1 - 5.9e-05 22.8 2.3 0.00017 21.3 1.4 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.13 KXG45877.1 - 0.0056 15.2 0.0 1.4 7.4 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II AXE1 PF05448.12 KXG45877.1 - 0.015 14.0 0.0 0.042 12.5 0.0 1.7 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase PF00756.20 KXG45877.1 - 0.017 14.8 0.2 0.057 13.1 0.2 1.8 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KXG45877.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cpn60_TCP1 PF00118.24 KXG45878.1 - 5e-148 493.8 12.3 5.6e-148 493.6 12.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA PF00004.29 KXG45879.1 - 1.5e-40 138.7 0.0 2.6e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXG45879.1 - 8.8e-06 25.4 0.1 2e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KXG45879.1 - 9.1e-05 22.8 0.0 0.0059 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KXG45879.1 - 0.00013 22.0 0.1 0.00062 19.8 0.0 2.1 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXG45879.1 - 0.00042 20.5 0.0 0.0013 18.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXG45879.1 - 0.00054 20.4 0.1 0.011 16.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KXG45879.1 - 0.0015 17.8 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KXG45879.1 - 0.0094 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KXG45879.1 - 0.03 13.8 0.0 0.095 12.2 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KXG45879.1 - 0.03 14.6 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXG45879.1 - 0.051 13.7 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXG45879.1 - 0.06 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KXG45879.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXG45879.1 - 0.1 12.3 0.1 0.27 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXG45879.1 - 0.1 12.3 0.1 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KXG45879.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain FAD_binding_2 PF00890.24 KXG45880.1 - 4.8e-125 417.9 4.3 6.8e-125 417.4 4.3 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KXG45880.1 - 1.9e-44 150.8 1.9 2.8e-44 150.2 1.9 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KXG45880.1 - 5.3e-08 32.4 0.2 0.00026 20.3 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG45880.1 - 1.1e-05 24.8 0.2 0.0094 15.2 0.1 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KXG45880.1 - 2.3e-05 23.6 1.0 0.0093 15.1 1.4 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KXG45880.1 - 0.0026 17.1 0.2 0.0055 16.0 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXG45880.1 - 0.013 15.1 1.5 0.036 13.6 1.5 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KXG45880.1 - 0.14 10.9 1.9 0.46 9.1 0.6 2.4 3 0 0 3 3 3 0 HI0933-like protein PAPS_reduct PF01507.19 KXG45880.1 - 0.19 11.7 0.2 0.36 10.9 0.2 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Pyr_redox_3 PF13738.6 KXG45880.1 - 1.7 7.8 3.6 4.6 6.4 0.9 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Adeno_E3_CR2 PF02439.15 KXG45881.1 - 1.6e-06 27.7 2.6 2.9e-06 26.9 2.6 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Mid2 PF04478.12 KXG45881.1 - 0.00028 20.7 0.0 0.00082 19.2 0.0 1.8 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 KXG45881.1 - 0.0071 17.2 0.0 0.018 15.9 0.0 1.7 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KXG45881.1 - 0.041 12.7 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Amnionless Herpes_gE PF02480.16 KXG45881.1 - 0.064 12.0 0.0 0.095 11.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DAG1 PF05454.11 KXG45881.1 - 0.07 12.5 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) SKG6 PF08693.10 KXG45881.1 - 0.074 12.5 1.9 0.15 11.4 1.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MMTV_SAg PF01054.17 KXG45881.1 - 0.075 12.6 2.2 0.69 9.4 2.2 2.1 1 1 0 1 1 1 0 Mouse mammary tumour virus superantigen Beta-APP PF03494.13 KXG45881.1 - 0.15 11.9 3.5 0.33 10.8 3.5 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Syndecan PF01034.20 KXG45881.1 - 0.28 11.1 0.9 0.67 9.9 0.5 1.7 2 0 0 2 2 2 0 Syndecan domain Lyase_1 PF00206.20 KXG45882.1 - 2.1e-82 277.0 0.0 4e-82 276.1 0.0 1.5 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KXG45882.1 - 4.4e-24 85.0 0.0 1.5e-23 83.3 0.0 2.0 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal FR47 PF08445.10 KXG45883.1 - 4.9e-07 29.6 0.1 0.00076 19.4 0.1 2.3 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KXG45883.1 - 0.017 15.8 0.0 0.033 14.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG45883.1 - 0.1 12.8 0.0 0.28 11.4 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Fungal_trans PF04082.18 KXG45886.1 - 8.9e-12 44.6 0.9 1.9e-11 43.5 0.9 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KXG45887.1 - 3e-57 194.4 0.0 3.8e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SH3BGR PF04908.15 KXG45887.1 - 0.061 13.5 0.1 7.5 6.8 0.1 2.5 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein SH3_9 PF14604.6 KXG45889.1 - 2.5e-24 84.9 1.1 2.8e-11 43.1 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 KXG45889.1 - 6.6e-23 80.8 0.6 2.8e-22 78.8 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KXG45889.1 - 2.8e-17 62.0 1.3 7.8e-10 38.2 0.0 2.7 3 0 0 3 3 3 2 SH3 domain C1_1 PF00130.22 KXG45889.1 - 8.3e-16 57.6 5.0 1.4e-15 56.9 5.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.17 KXG45889.1 - 8.8e-06 25.3 0.1 0.00033 20.3 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_10 PF17902.1 KXG45889.1 - 0.00083 19.4 0.0 0.77 9.9 0.0 2.7 2 0 0 2 2 2 2 SH3 domain C1_2 PF03107.16 KXG45889.1 - 0.0058 16.9 4.2 0.01 16.1 4.2 1.4 1 0 0 1 1 1 1 C1 domain SH3_3 PF08239.11 KXG45889.1 - 0.017 15.4 0.7 0.14 12.4 0.1 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain Cortex-I_coil PF09304.10 KXG45889.1 - 0.074 13.3 8.0 1.9 8.7 0.1 3.5 3 1 0 4 4 3 0 Cortexillin I, coiled coil FYVE PF01363.21 KXG45889.1 - 0.14 12.3 2.4 0.31 11.2 2.4 1.5 1 0 0 1 1 1 0 FYVE zinc finger OrfB_Zn_ribbon PF07282.11 KXG45889.1 - 3.9 7.5 5.2 10 6.1 5.2 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-RING_9 PF13901.6 KXG45889.1 - 6.9 6.6 8.6 1.1e+02 2.6 8.6 2.4 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon DEAD PF00270.29 KXG45890.1 - 1.8e-33 115.8 0.2 3.7e-33 114.7 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG45890.1 - 1.5e-23 83.3 0.0 3.4e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KXG45890.1 - 0.074 12.8 0.2 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain IMPa_N_2 PF18650.1 KXG45890.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain CMS1 PF14617.6 KXG45890.1 - 0.14 11.4 0.1 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Fungal_trans PF04082.18 KXG45891.1 - 3.3e-08 32.9 0.1 7.5e-08 31.7 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain TAP_C PF03943.13 KXG45891.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.3 3 0 0 3 3 3 0 TAP C-terminal domain GTP_CH_N PF12471.8 KXG45892.1 - 2.8e-89 298.0 0.0 3.9e-89 297.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KXG45892.1 - 1.6e-17 63.6 0.0 2.3e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II GntR PF00392.21 KXG45892.1 - 0.17 11.6 0.0 6 6.6 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family DUF2014 PF09427.10 KXG45893.1 - 3.3e-97 324.9 0.0 4.8e-97 324.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 KXG45893.1 - 2.5e-18 65.8 0.3 5.8e-18 64.6 0.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CCDC85 PF10226.9 KXG45893.1 - 0.078 12.6 1.1 0.14 11.8 1.1 1.4 1 0 0 1 1 1 0 CCDC85 family PRKG1_interact PF15898.5 KXG45893.1 - 0.12 13.3 3.1 0.3 12.0 3.1 1.8 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain TSC22 PF01166.18 KXG45893.1 - 0.19 12.0 0.7 0.9 9.9 0.4 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family ZapB PF06005.12 KXG45893.1 - 0.22 12.0 2.0 0.29 11.6 0.8 1.8 2 0 0 2 2 2 0 Cell division protein ZapB HOOK PF05622.12 KXG45893.1 - 0.25 9.4 2.6 0.39 8.8 2.6 1.2 1 0 0 1 1 1 0 HOOK protein Ferric_reduct PF01794.19 KXG45894.1 - 3.8e-19 69.0 9.3 1.1e-18 67.5 9.3 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXG45894.1 - 9.5e-18 64.8 0.1 1.7e-16 60.8 0.0 2.6 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXG45894.1 - 7.2e-12 45.4 0.0 1.2e-09 38.2 0.0 2.8 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXG45894.1 - 0.052 14.2 0.3 0.61 10.8 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF3632 PF12311.8 KXG45895.1 - 3.3e-27 96.0 0.2 4.5e-27 95.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) FSH1 PF03959.13 KXG45896.1 - 8.9e-30 103.9 0.0 1.5e-29 103.2 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ADH_zinc_N PF00107.26 KXG45897.1 - 3.5e-13 49.7 0.0 6.8e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG45897.1 - 1.2e-06 28.4 0.2 1.4e-05 25.0 0.1 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXG45897.1 - 2.8e-05 25.2 0.0 0.00017 22.7 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase E1-E2_ATPase PF00122.20 KXG45898.1 - 3.3e-41 140.8 8.9 2.1e-31 108.9 0.0 3.6 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXG45898.1 - 2.1e-27 96.0 3.0 2.1e-27 96.0 3.0 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXG45898.1 - 3e-17 63.6 0.0 5.9e-16 59.4 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXG45898.1 - 1.1e-16 60.2 0.1 3.1e-16 58.8 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KXG45898.1 - 9.9e-14 51.2 0.0 1.8e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXG45898.1 - 7.5e-06 25.9 3.3 8.6e-06 25.7 1.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KXG45898.1 - 0.024 14.5 1.6 0.072 13.0 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) RNase_PH PF01138.21 KXG45899.1 - 0.0095 16.4 0.0 0.024 15.1 0.0 1.7 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_kinase PF01513.21 KXG45900.1 - 3.8e-79 265.9 0.0 5.3e-79 265.5 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Mannosyl_trans3 PF11051.8 KXG45901.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_transf_8 PF01501.20 KXG45901.1 - 0.03 13.9 0.1 4.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 8 GAF_2 PF13185.6 KXG45903.1 - 8e-12 45.6 0.0 1.3e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KXG45903.1 - 2.9e-08 34.4 0.0 4.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KXG45903.1 - 0.0018 18.6 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 GAF domain SpoVT_C PF15714.5 KXG45903.1 - 0.1 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor adh_short PF00106.25 KXG45904.1 - 5.3e-54 182.7 1.1 7.4e-54 182.2 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG45904.1 - 1.5e-51 175.2 2.8 1.7e-51 175.0 2.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG45904.1 - 6.4e-12 45.7 0.1 9.4e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXG45904.1 - 7.9e-06 25.9 0.1 1.6e-05 24.8 0.1 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KXG45904.1 - 6.6e-05 22.5 0.1 0.0001 21.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KXG45904.1 - 0.00036 21.0 0.1 0.0007 20.1 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 KXG45904.1 - 0.0004 19.6 0.1 0.00058 19.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXG45904.1 - 0.0005 19.2 0.1 0.00073 18.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXG45904.1 - 0.00073 19.0 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KXG45904.1 - 0.003 17.8 0.1 0.0055 17.0 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain RmlD_sub_bind PF04321.17 KXG45904.1 - 0.0058 15.8 0.0 0.0081 15.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Methyltransf_12 PF08242.12 KXG45904.1 - 0.013 16.2 0.0 0.022 15.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ApbA PF02558.16 KXG45904.1 - 0.027 14.1 0.1 0.047 13.3 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Methyltransf_25 PF13649.6 KXG45904.1 - 0.028 15.1 0.0 0.053 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_10 PF13460.6 KXG45904.1 - 0.037 13.9 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_7 PF13241.6 KXG45904.1 - 0.051 14.0 0.0 0.085 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Ldh_1_N PF00056.23 KXG45904.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 KXG45904.1 - 0.095 13.4 0.1 0.19 12.4 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KXG45904.1 - 0.11 12.5 3.4 0.078 13.0 1.1 2.0 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Staph_opine_DH PF10100.9 KXG45904.1 - 0.12 10.9 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase PRELI PF04707.14 KXG45906.1 - 7.2e-25 87.6 0.0 7.2e-21 74.6 0.0 2.5 2 1 0 2 2 2 2 PRELI-like family Metallophos PF00149.28 KXG45908.1 - 2.2e-11 44.6 1.6 4.5e-11 43.6 1.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EGF_CA PF07645.15 KXG45908.1 - 1.6 9.0 5.7 1.3 9.3 2.0 2.7 2 0 0 2 2 2 0 Calcium-binding EGF domain MARVEL PF01284.23 KXG45909.1 - 1.9e-30 105.8 11.1 2.4e-30 105.5 11.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain Clat_adaptor_s PF01217.20 KXG45910.1 - 1.8e-53 180.3 1.6 2.1e-53 180.0 1.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Fungal_trans_2 PF11951.8 KXG45910.1 - 0.034 12.9 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Maf1 PF09174.10 KXG45911.1 - 3.8e-60 203.0 0.0 4.9e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Filament PF00038.21 KXG45912.1 - 2.4e-07 30.6 20.5 2.4e-07 30.6 20.5 4.5 3 2 2 5 5 5 1 Intermediate filament protein ATG16 PF08614.11 KXG45912.1 - 0.00072 19.8 30.6 0.00072 19.8 30.6 5.5 2 2 3 5 5 5 2 Autophagy protein 16 (ATG16) ORF11CD3 PF10549.9 KXG45912.1 - 0.016 15.3 0.6 0.016 15.3 0.6 2.8 3 0 0 3 3 3 0 ORF11CD3 domain APG17 PF04108.12 KXG45912.1 - 0.096 11.8 30.2 0.13 11.3 17.7 2.4 1 1 1 2 2 2 0 Autophagy protein Apg17 DASH_Dam1 PF08653.10 KXG45912.1 - 3.3 7.6 4.6 21 5.0 0.1 3.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 HMMR_N PF15905.5 KXG45912.1 - 5.2 6.4 55.2 4.5 6.6 46.5 2.6 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal T2SSF PF00482.23 KXG45912.1 - 6.3 6.8 5.9 12 5.9 0.1 3.1 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Spc29 PF17082.5 KXG45912.1 - 8.6 6.1 32.2 1.7 8.4 4.6 3.7 1 1 2 3 3 3 0 Spindle Pole Component 29 Pkinase PF00069.25 KXG45913.1 - 2.2e-54 184.6 0.0 3e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain COPIIcoated_ERV PF07970.12 KXG45913.1 - 3.9e-35 121.7 0.0 7e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KXG45913.1 - 3.7e-24 84.9 0.0 6.8e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase_Tyr PF07714.17 KXG45913.1 - 2.2e-19 69.8 0.0 4e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pex24p PF06398.11 KXG45914.1 - 6.8e-60 203.0 0.0 3.9e-59 200.5 0.0 1.7 1 1 1 2 2 2 1 Integral peroxisomal membrane peroxin Nop16 PF09420.10 KXG45915.1 - 4.6e-63 213.0 9.5 5.3e-63 212.9 9.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zip PF02535.22 KXG45916.1 - 8.1e-57 192.9 7.1 1.8e-56 191.8 7.1 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Anp1 PF03452.14 KXG45917.1 - 4.2e-108 360.7 0.0 5.1e-108 360.5 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KXG45917.1 - 0.047 13.5 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Mito_carr PF00153.27 KXG45918.1 - 2.1e-55 184.6 1.1 5.2e-18 64.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ASC PF00858.24 KXG45918.1 - 0.4 9.6 1.0 0.55 9.1 1.0 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel CCDC14 PF15254.6 KXG45919.1 - 0.57 8.8 3.8 0.77 8.3 3.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 tRNA-synt_1b PF00579.25 KXG45920.1 - 1.1e-16 61.1 0.1 4.7e-16 58.9 0.1 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Aminotran_4 PF01063.19 KXG45921.1 - 3.7e-37 128.3 0.0 4.5e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV TPR_1 PF00515.28 KXG45922.1 - 1.2e-37 126.2 23.6 0.0013 18.5 0.1 11.2 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KXG45922.1 - 2.3e-35 117.8 24.6 7.1e-05 22.6 0.1 11.0 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.6 KXG45922.1 - 8.8e-24 83.9 13.5 1e-05 26.1 0.0 6.9 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 KXG45922.1 - 8.6e-19 67.0 22.1 0.00011 21.8 0.0 8.7 6 1 2 8 8 8 6 TPR repeat TPR_8 PF13181.6 KXG45922.1 - 1.3e-18 65.5 19.3 0.0098 16.0 0.1 9.5 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXG45922.1 - 1.8e-15 56.1 6.3 0.28 11.6 0.0 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 KXG45922.1 - 5.4e-14 52.1 10.3 3e-05 24.1 0.1 5.4 4 1 1 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXG45922.1 - 1.7e-13 50.6 31.4 0.00088 19.5 2.4 9.1 5 2 4 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXG45922.1 - 1.7e-11 44.0 11.4 0.023 15.5 0.0 7.6 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXG45922.1 - 1.8e-10 41.2 20.8 5.7e-05 23.6 0.8 6.8 6 1 3 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXG45922.1 - 3.2e-10 39.3 19.2 0.025 14.6 0.1 8.5 7 1 1 8 8 8 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 KXG45922.1 - 7.5e-07 28.5 5.5 0.12 11.8 0.0 6.4 6 0 0 6 6 6 1 SHNi-TPR TPR_10 PF13374.6 KXG45922.1 - 7.8e-06 25.6 17.5 0.23 11.4 0.4 8.5 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXG45922.1 - 1.5e-05 24.5 4.2 2.1e-05 24.0 2.0 2.2 1 1 1 2 2 2 1 MalT-like TPR region ANAPC3 PF12895.7 KXG45922.1 - 7.4e-05 22.9 15.0 0.13 12.5 0.0 5.2 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KXG45922.1 - 0.0022 18.5 22.1 6.6 7.6 0.0 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat MAS20 PF02064.15 KXG45922.1 - 0.0029 17.7 11.3 0.13 12.4 0.2 4.5 4 2 1 5 5 5 1 MAS20 protein import receptor Sel1 PF08238.12 KXG45922.1 - 0.017 15.8 6.1 0.89 10.3 0.2 4.5 4 0 0 4 4 3 0 Sel1 repeat Herpes_TAF50 PF03326.13 KXG45922.1 - 0.047 12.4 1.0 1.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus transcription activation factor (transactivator) HemY_N PF07219.13 KXG45922.1 - 0.056 13.6 5.6 26 5.0 0.9 4.4 3 1 1 4 4 4 0 HemY protein N-terminus RhoGEF67_u2 PF16614.5 KXG45922.1 - 0.065 13.3 0.4 0.23 11.6 0.4 1.9 1 0 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 MIT PF04212.18 KXG45922.1 - 0.86 9.7 18.4 9.7 6.3 0.1 6.7 7 1 0 7 7 6 0 MIT (microtubule interacting and transport) domain ANAPC5 PF12862.7 KXG45922.1 - 1.7 8.8 12.4 17 5.6 0.0 4.4 4 2 1 5 5 3 0 Anaphase-promoting complex subunit 5 FHA PF00498.26 KXG45923.1 - 2.5e-13 50.2 0.0 4.6e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain Ost5 PF05251.12 KXG45923.1 - 0.092 13.0 0.7 0.19 12.0 0.7 1.5 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 Yop-YscD_cpl PF16697.5 KXG45923.1 - 0.13 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DUF3500 PF12006.8 KXG45924.1 - 4.5e-110 367.8 0.0 5.4e-110 367.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) L_HMGIC_fpl PF10242.9 KXG45925.1 - 9.3e-05 22.7 5.2 0.00016 21.9 5.2 1.4 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein SPC12 PF06645.13 KXG45925.1 - 0.45 10.6 7.9 0.5 10.5 0.2 3.1 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) PIG-Y PF15159.6 KXG45925.1 - 1.7 9.6 9.7 7.7 7.5 2.3 2.7 2 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y TMEM43 PF07787.12 KXG45925.1 - 3.5 6.9 5.8 0.55 9.6 0.7 2.0 2 0 0 2 2 2 0 Transmembrane protein 43 RRM_1 PF00076.22 KXG45926.1 - 3.3e-57 190.2 0.1 3.2e-19 68.5 0.1 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXG45926.1 - 7e-34 115.5 0.0 1.2e-27 95.6 0.0 4.4 4 0 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXG45926.1 - 2.2e-07 30.7 0.0 0.037 14.0 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 KXG45926.1 - 0.00026 20.9 0.0 0.2 11.6 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.11 KXG45926.1 - 0.0036 16.7 1.5 0.01 15.3 1.5 1.8 1 0 0 1 1 1 1 Lsm interaction motif TPR_14 PF13428.6 KXG45926.1 - 0.14 13.0 3.3 4.6 8.3 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF702 PF05142.12 KXG45926.1 - 0.87 10.1 2.6 3.3 8.2 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Ribosomal_L22 PF00237.19 KXG45927.1 - 1.3e-30 105.6 0.0 2.7e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e His_Phos_1 PF00300.22 KXG45928.1 - 1.4e-09 37.9 2.3 6.8e-09 35.7 1.3 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.25 KXG45930.1 - 1.5e-73 247.4 0.0 2.1e-73 247.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG45930.1 - 1.8e-35 122.5 0.0 2.5e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KXG45930.1 - 2.2e-19 70.0 0.1 8.9e-13 48.7 0.0 2.5 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KXG45930.1 - 1.5e-13 50.6 0.0 4.4e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KXG45930.1 - 1.8e-05 24.2 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KXG45930.1 - 0.00037 20.1 0.1 0.00083 19.0 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KXG45930.1 - 0.0067 15.4 0.2 0.015 14.3 0.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXG45930.1 - 0.024 14.0 0.2 0.055 12.8 0.2 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 KXG45930.1 - 0.095 11.5 0.2 0.14 10.9 0.2 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 KXG45930.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KXG45930.1 - 0.16 10.9 0.3 0.25 10.2 0.3 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HA PF03457.14 KXG45931.1 - 0.055 13.8 0.1 0.17 12.2 0.1 1.8 1 0 0 1 1 1 0 Helicase associated domain Capsid-VNN PF11729.8 KXG45931.1 - 0.82 8.6 4.7 0.77 8.7 2.9 1.8 2 1 0 2 2 2 0 nodavirus capsid protein C2 PF00168.30 KXG45932.1 - 2.1e-16 60.1 0.0 5.3e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain TFIIA PF03153.13 KXG45932.1 - 0.0044 17.1 46.1 0.0044 17.1 46.1 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Lys-AminoMut_A PF09043.11 KXG45932.1 - 5.2 5.4 8.2 7.3 4.9 8.2 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit UTP15_C PF09384.10 KXG45933.1 - 6.2e-52 175.2 2.5 6.2e-52 175.2 2.5 1.7 2 0 0 2 2 2 1 UTP15 C terminal WD40 PF00400.32 KXG45933.1 - 4.3e-18 65.3 0.8 0.00025 21.7 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG45933.1 - 3.1e-07 30.6 0.3 0.016 15.5 0.0 3.9 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 KXG45933.1 - 0.00073 18.9 0.0 0.0036 16.7 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region VID27 PF08553.10 KXG45933.1 - 0.051 12.6 0.0 0.2 10.7 0.0 1.9 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain RAB3GAP2_N PF14655.6 KXG45933.1 - 0.076 12.3 0.2 14 4.8 0.2 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PhyH PF05721.13 KXG45934.1 - 1.3e-44 153.0 0.0 1.5e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_MOT1 PF16983.5 KXG45936.1 - 4e-63 210.7 35.2 9.7e-34 116.1 9.2 3.2 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 KXG45936.1 - 0.11 11.2 28.0 1.2e+02 1.2 28.0 2.7 1 1 0 1 1 1 0 Sulfate permease family ABC2_membrane PF01061.24 KXG45937.1 - 1.2e-83 279.7 68.6 3.7e-47 160.4 22.9 3.8 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KXG45937.1 - 2.5e-37 128.4 0.0 3.7e-17 63.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXG45937.1 - 8.3e-34 115.4 18.4 8e-30 102.6 0.1 4.4 5 0 0 5 5 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KXG45937.1 - 2.7e-14 53.5 0.3 7.5e-14 52.1 0.3 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 KXG45937.1 - 4.2e-07 29.7 0.1 4.5e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KXG45937.1 - 4.4e-07 29.3 47.6 3.9e-06 26.2 17.1 3.4 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KXG45937.1 - 4.5e-06 27.2 0.1 0.0006 20.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXG45937.1 - 2.3e-05 24.4 0.1 0.0065 16.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KXG45937.1 - 0.00035 20.8 0.1 0.011 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXG45937.1 - 0.00061 19.5 1.6 0.049 13.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KXG45937.1 - 0.0029 17.1 0.0 0.025 14.0 0.0 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXG45937.1 - 0.0043 17.3 0.1 1.4 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXG45937.1 - 0.0043 17.6 0.0 0.028 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KXG45937.1 - 0.0064 16.1 0.8 0.044 13.4 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 KXG45937.1 - 0.0093 15.8 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KXG45937.1 - 0.011 15.5 0.0 1.6 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXG45937.1 - 0.012 15.6 0.0 4.4 7.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 KXG45937.1 - 0.082 12.8 0.2 2.3 8.1 0.1 2.6 2 0 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 KXG45937.1 - 0.1 12.5 0.1 0.92 9.4 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_17 PF13207.6 KXG45937.1 - 0.13 12.7 0.6 1.2 9.5 0.0 2.8 4 0 0 4 4 2 0 AAA domain PufQ PF05398.11 KXG45937.1 - 0.74 10.0 3.3 26 5.0 0.1 2.7 2 0 0 2 2 2 0 PufQ cytochrome subunit TMEM234 PF10639.9 KXG45938.1 - 3.9e-29 101.0 0.2 5.2e-21 74.8 0.3 2.7 2 1 0 2 2 2 2 Putative transmembrane family 234 EamA PF00892.20 KXG45938.1 - 0.024 14.8 4.9 1.8 8.7 2.1 2.4 2 1 0 2 2 2 0 EamA-like transporter family Chitin_synth_1 PF01644.17 KXG45939.1 - 1.2e-75 252.9 0.0 2.4e-75 252.0 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KXG45939.1 - 2.5e-28 97.8 0.0 4.8e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KXG45939.1 - 1.1e-21 77.1 4.9 2.4e-18 66.1 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase LMWPc PF01451.21 KXG45940.1 - 6.8e-33 114.0 0.0 1.1e-26 93.9 0.0 2.2 2 1 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase COQ7 PF03232.13 KXG45941.1 - 1e-67 227.2 0.8 1.2e-67 227.0 0.8 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KXG45941.1 - 1.5e-06 28.7 2.9 5.9e-06 26.7 0.1 2.1 1 1 1 2 2 2 1 Rubrerythrin Crr6 PF08847.11 KXG45941.1 - 0.076 12.7 0.1 0.74 9.5 0.0 2.1 1 1 1 2 2 2 0 Chlororespiratory reduction 6 UPF0184 PF03670.13 KXG45941.1 - 0.12 12.8 0.5 0.19 12.2 0.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) SPT2 PF08243.11 KXG45941.1 - 0.42 11.1 4.5 0.69 10.5 4.5 1.2 1 0 0 1 1 1 0 SPT2 chromatin protein Plus-3 PF03126.18 KXG45942.1 - 1.2e-30 106.2 0.0 2.4e-29 102.0 0.0 2.5 2 0 0 2 2 2 1 Plus-3 domain MRC1 PF09444.10 KXG45943.1 - 2.5e-38 131.9 22.5 2.5e-38 131.9 22.5 7.7 5 4 3 8 8 8 2 MRC1-like domain KR PF08659.10 KXG45943.1 - 0.0071 16.3 1.1 0.0071 16.3 1.1 2.5 3 0 0 3 3 3 1 KR domain SPATA9 PF15824.5 KXG45943.1 - 1.1 8.5 5.0 1 8.6 2.9 1.9 2 0 0 2 2 2 0 Spermatogenesis-associated protein 9 3HCDH_N PF02737.18 KXG45944.1 - 1.5e-28 99.9 0.0 2.1e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXG45944.1 - 2.5e-21 76.1 0.0 2.1e-20 73.2 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain TrkA_N PF02254.18 KXG45944.1 - 0.0019 18.4 0.0 0.0085 16.3 0.0 1.9 1 1 0 1 1 1 1 TrkA-N domain NAD_Gly3P_dh_N PF01210.23 KXG45944.1 - 0.0039 17.2 0.1 0.0084 16.1 0.1 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 KXG45944.1 - 0.012 15.8 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KXG45944.1 - 0.015 14.9 0.0 0.26 10.9 0.1 2.3 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KXG45944.1 - 0.021 14.1 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 KXG45944.1 - 0.046 14.0 0.0 0.095 13.0 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KXG45944.1 - 0.06 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KXG45944.1 - 0.14 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain F420_oxidored PF03807.17 KXG45944.1 - 0.16 12.6 0.0 0.28 11.8 0.0 1.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Hydrolase_like PF13242.6 KXG45945.1 - 2.4e-06 27.5 0.0 7.1e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KXG45945.1 - 0.028 14.5 0.0 0.074 13.1 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase GMC_oxred_N PF00732.19 KXG45946.1 - 1.2e-27 97.0 0.0 2.1e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG45946.1 - 1e-19 71.5 0.3 1.9e-19 70.6 0.3 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KXG45946.1 - 1.3e-07 31.6 0.8 0.0027 17.4 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KXG45946.1 - 3.9e-07 29.1 0.3 3.3e-05 22.8 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KXG45946.1 - 1.7e-06 27.4 0.9 0.0089 15.2 0.5 2.4 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KXG45946.1 - 1.3e-05 24.7 0.0 0.00044 19.7 0.2 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG45946.1 - 2.5e-05 23.7 0.1 0.0016 17.8 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG45946.1 - 3.9e-05 24.1 0.2 0.039 14.5 0.1 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG45946.1 - 0.00023 20.5 2.4 0.023 14.0 0.8 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG45946.1 - 0.0005 20.2 0.0 0.002 18.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXG45946.1 - 0.0025 17.1 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXG45946.1 - 0.0045 16.2 0.1 0.0097 15.2 0.1 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KXG45946.1 - 0.0062 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXG45946.1 - 0.044 12.8 0.2 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KXG45946.1 - 0.14 10.9 0.1 0.23 10.3 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Jnk-SapK_ap_N PF09744.9 KXG45947.1 - 0.24 11.6 0.0 0.79 9.9 0.0 1.7 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 G-7-MTase PF12803.7 KXG45948.1 - 8.2e-05 21.9 0.0 0.00011 21.5 0.0 1.1 1 0 0 1 1 1 1 mRNA (guanine-7-)methyltransferase (G-7-MTase) Pyr_redox_2 PF07992.14 KXG45949.1 - 2.3e-09 36.9 0.0 4.6e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXG45949.1 - 9.9e-09 34.1 0.3 2.3e-07 29.6 0.0 2.7 2 2 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXG45949.1 - 3.2e-07 30.5 0.2 2.3e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXG45949.1 - 8.6e-07 28.5 0.0 4.5e-06 26.1 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG45949.1 - 1.3e-06 27.8 0.0 8.5e-05 21.8 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 KXG45949.1 - 0.057 12.8 0.1 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 KXG45949.1 - 0.32 10.2 0.3 0.69 9.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KXG45949.1 - 0.66 10.6 2.6 35 5.1 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXG45950.1 - 6.4e-20 71.7 0.1 2.2e-11 43.6 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXG45950.1 - 1e-07 32.1 0.4 2.7e-07 30.7 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXG45950.1 - 0.00011 22.0 0.5 0.0005 19.8 0.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG45950.1 - 0.0018 17.6 0.5 0.011 14.9 0.6 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG45950.1 - 0.0029 16.8 1.6 0.0035 16.5 0.8 1.6 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KXG45950.1 - 0.022 13.6 0.2 0.033 13.0 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 KXG45950.1 - 0.048 12.9 0.1 0.084 12.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.21 KXG45950.1 - 0.087 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 ThiF family GIDA PF01134.22 KXG45950.1 - 0.19 10.8 0.6 0.29 10.2 0.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A MIF4G PF02854.19 KXG45952.1 - 2e-20 73.3 0.1 3.8e-20 72.4 0.1 1.5 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KXG45952.1 - 3.9e-18 65.5 0.1 1.7e-17 63.4 0.0 2.2 2 0 0 2 2 2 1 MA3 domain SRP14 PF02290.15 KXG45953.1 - 2e-25 89.0 0.0 3.5e-25 88.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle 14kD protein Inp1 PF12634.7 KXG45954.1 - 9.2e-41 139.1 0.0 1.9e-40 138.1 0.0 1.5 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 EI24 PF07264.11 KXG45955.1 - 4.3e-12 46.6 4.9 4.8e-05 23.7 0.0 2.3 1 1 1 2 2 2 2 Etoposide-induced protein 2.4 (EI24) FmdA_AmdA PF03069.15 KXG45956.1 - 1.9e-180 599.6 0.0 2.2e-180 599.4 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Pro_isomerase PF00160.21 KXG45957.1 - 1.2e-29 103.7 0.1 2e-29 102.9 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 KXG45957.1 - 8.3e-05 22.2 0.9 8.3e-05 22.2 0.9 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXG45957.1 - 0.00017 21.4 10.9 0.00044 20.2 1.8 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXG45957.1 - 0.0037 17.4 0.7 0.0037 17.4 0.7 3.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXG45957.1 - 0.012 15.3 3.3 14 5.5 0.0 3.5 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.6 KXG45957.1 - 0.017 15.4 6.3 0.11 12.8 5.7 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXG45957.1 - 0.038 14.2 1.6 0.83 9.8 1.6 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXG45957.1 - 0.052 14.2 9.7 0.56 10.9 10.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXG45957.1 - 0.11 13.4 1.5 0.11 13.4 1.5 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Pro_isomerase PF00160.21 KXG45958.1 - 6.4e-06 26.5 0.0 7.1e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Tyr_Deacylase PF02580.16 KXG45959.1 - 3.1e-52 176.9 0.0 4.1e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.15 KXG45960.1 - 2.4e-86 288.9 19.3 3.4e-86 288.4 19.3 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KXG45960.1 - 4.3e-44 149.8 11.5 8.9e-44 148.8 11.5 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Cep57_MT_bd PF06657.13 KXG45960.1 - 0.0028 18.1 7.4 0.26 11.8 0.7 2.8 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 Syntaxin_2 PF14523.6 KXG45960.1 - 0.029 14.8 2.1 0.029 14.8 2.1 2.4 3 0 0 3 3 3 0 Syntaxin-like protein DUF2373 PF10180.9 KXG45960.1 - 0.069 13.0 5.4 0.03 14.2 2.4 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) GIT_CC PF16559.5 KXG45960.1 - 0.15 12.0 0.5 1.5 8.7 0.1 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlaC_arch PF05377.11 KXG45960.1 - 0.33 11.4 4.6 2.6 8.5 0.0 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Snapin_Pallidin PF14712.6 KXG45960.1 - 0.46 10.9 9.1 0.1 13.0 1.2 2.5 2 1 1 3 3 3 0 Snapin/Pallidin DUF2353 PF09789.9 KXG45960.1 - 0.52 9.6 13.6 0.85 8.9 13.6 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) LZ_Tnp_IS66 PF13007.7 KXG45960.1 - 1.2 10.0 8.9 4.4 8.2 0.3 3.7 3 0 0 3 3 3 0 Transposase C of IS166 homeodomain DUF641 PF04859.12 KXG45960.1 - 8.3 6.8 11.1 3.6e+02 1.5 11.1 2.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF2951 PF11166.8 KXG45960.1 - 9.7 6.5 8.8 0.56 10.5 1.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) zf-C2H2 PF00096.26 KXG45961.1 - 1.8e-05 24.9 17.8 3.8e-05 23.9 1.9 3.5 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXG45961.1 - 0.0009 19.9 1.8 0.0009 19.9 1.8 3.8 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2HE PF16278.5 KXG45961.1 - 0.002 18.5 0.3 0.022 15.2 0.0 2.3 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KXG45961.1 - 4.3 7.5 16.1 0.17 11.9 1.4 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXG45961.1 - 8.1 7.1 16.8 3.3 8.3 1.6 3.7 3 0 0 3 3 3 0 Zinc-finger double domain DNA_binding_1 PF01035.20 KXG45962.1 - 1.4e-27 95.6 0.0 2e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain YadA_anchor PF03895.15 KXG45962.1 - 0.2 11.8 0.1 0.2 11.8 0.1 1.8 2 0 0 2 2 2 0 YadA-like membrane anchor domain Sugar_tr PF00083.24 KXG45963.1 - 1e-86 291.6 22.7 1.2e-86 291.4 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG45963.1 - 9.9e-22 77.3 48.2 2.1e-16 59.8 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXG45963.1 - 1.5 7.0 13.7 0.48 8.6 1.8 3.3 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_16 PF00722.21 KXG45964.1 - 1e-06 28.4 0.1 2e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.16 KXG45965.1 - 6.1e-44 150.4 22.3 1e-43 149.6 22.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG45965.1 - 4.3e-08 32.5 11.1 4.3e-08 32.5 11.1 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXG45965.1 - 3.7e-07 29.0 2.6 5.3e-07 28.5 2.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) nsp9 PF08710.10 KXG45965.1 - 0.084 13.3 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 nsp9 replicase Pyr_redox_2 PF07992.14 KXG45966.1 - 5.9e-70 235.8 7.7 5.9e-70 235.8 7.7 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXG45966.1 - 2.8e-41 140.2 1.2 5.9e-41 139.2 0.2 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXG45966.1 - 1.8e-21 76.5 8.5 6.7e-20 71.4 1.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXG45966.1 - 1.4e-11 44.4 7.6 2.3e-10 40.4 0.7 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG45966.1 - 9.8e-10 38.5 4.0 4.7e-05 23.5 0.5 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXG45966.1 - 1.1e-08 34.7 6.9 6e-07 29.0 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXG45966.1 - 1.2e-08 34.5 14.1 3.6e-07 29.6 5.3 3.1 2 2 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXG45966.1 - 3e-07 29.9 12.3 8e-07 28.5 2.7 3.2 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 KXG45966.1 - 5e-07 29.2 0.5 0.011 14.8 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KXG45966.1 - 3.4e-06 26.5 8.2 0.00055 19.3 0.9 3.1 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KXG45966.1 - 4.1e-05 23.3 15.1 0.039 13.5 0.5 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KXG45966.1 - 0.00011 21.1 15.1 0.00071 18.4 1.6 4.0 4 0 0 4 4 4 2 HI0933-like protein Lycopene_cycl PF05834.12 KXG45966.1 - 0.00055 19.1 3.6 0.017 14.2 0.1 2.4 2 1 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 KXG45966.1 - 0.00079 18.7 9.1 0.0011 18.3 1.1 2.5 1 1 1 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KXG45966.1 - 0.14 11.4 12.2 0.53 9.5 1.0 3.2 3 1 0 3 3 3 0 FAD binding domain FMO-like PF00743.19 KXG45966.1 - 0.27 9.6 3.0 1.4 7.3 0.8 2.6 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.14 KXG45966.1 - 1.9 7.2 7.6 1.1 8.0 0.6 2.3 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.6 KXG45966.1 - 3.9 8.0 8.7 0.3 11.5 0.7 3.1 3 2 0 4 4 3 0 Putative NAD(P)-binding Asparaginase PF00710.20 KXG45967.1 - 2.4e-48 164.2 1.0 2.4e-48 164.2 1.0 1.7 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KXG45967.1 - 1.1e-20 74.0 0.2 3.9e-20 72.2 0.1 1.9 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain AAA_26 PF13500.6 KXG45967.1 - 0.034 14.0 0.1 1.2 8.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain Ldh_1_C PF02866.18 KXG45967.1 - 0.065 13.2 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain PA PF02225.22 KXG45967.1 - 0.098 12.7 2.7 0.39 10.8 2.7 2.2 1 1 0 1 1 1 0 PA domain Glyco_hydro_72 PF03198.14 KXG45969.1 - 5.3e-86 288.7 0.8 3.6e-61 207.1 0.1 2.0 1 1 1 2 2 2 2 Glucanosyltransferase SKG6 PF08693.10 KXG45969.1 - 5.2e-08 32.2 0.6 1.1e-07 31.2 0.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 KXG45969.1 - 0.0021 18.2 0.1 0.0037 17.4 0.1 1.4 1 0 0 1 1 1 1 Podoplanin Stevor PF17410.2 KXG45969.1 - 0.0079 15.8 0.1 0.017 14.7 0.0 1.5 2 0 0 2 2 2 1 Subtelomeric Variable Open Reading frame Mid2 PF04478.12 KXG45969.1 - 0.027 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Rax2 PF12768.7 KXG45969.1 - 0.033 13.6 0.1 0.27 10.7 0.0 2.1 1 1 1 2 2 2 0 Cortical protein marker for cell polarity VSP PF03302.13 KXG45969.1 - 0.041 12.7 0.4 0.041 12.7 0.4 1.4 2 0 0 2 2 2 0 Giardia variant-specific surface protein Adeno_E3_CR2 PF02439.15 KXG45969.1 - 0.25 11.1 0.4 0.48 10.2 0.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pneumo_att_G PF05539.11 KXG45969.1 - 2.4 7.7 0.0 2.4 7.7 0.0 2.4 3 0 0 3 3 3 0 Pneumovirinae attachment membrane glycoprotein G MFS_1 PF07690.16 KXG45971.1 - 2e-34 119.1 35.9 2.4e-34 118.8 35.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXG45971.1 - 5.8e-08 32.4 8.8 5.8e-08 32.4 8.8 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB COesterase PF00135.28 KXG45972.1 - 5.6e-101 338.9 0.0 6.7e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG45972.1 - 1e-08 35.3 0.8 8.7e-08 32.3 0.8 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Helo_like_N PF17111.5 KXG45973.1 - 8.7e-08 31.8 3.8 8.7e-08 31.8 3.8 2.0 3 0 0 3 3 3 1 Fungal N-terminal domain of STAND proteins zf-C2H2_aberr PF17017.5 KXG45973.1 - 0.1 12.8 0.1 2.2 8.4 0.0 2.6 2 0 0 2 2 2 0 Aberrant zinc-finger BLI1 PF17324.2 KXG45973.1 - 0.55 10.9 5.0 0.87 10.3 0.5 2.9 2 1 0 2 2 2 0 BLOC-1 interactor 1 DUF2408 PF10303.9 KXG45973.1 - 5.3 7.6 8.0 3.9 8.0 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) ADH_zinc_N PF00107.26 KXG45974.1 - 1.6e-21 76.6 0.1 2.6e-21 76.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KXG45974.1 - 1.2e-16 60.5 0.0 2.6e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KXG45974.1 - 5.1e-06 27.6 0.0 9.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KXG45974.1 - 0.1 12.9 0.1 1.4 9.2 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain Pkinase PF00069.25 KXG45976.1 - 1e-09 38.2 0.0 1.4e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXG45976.1 - 9.4e-07 29.0 0.0 1.2e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXG45976.1 - 4.8e-06 26.1 0.0 6.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXG45976.1 - 0.00049 19.8 0.0 0.0008 19.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 KXG45976.1 - 0.00076 18.8 0.0 0.0013 18.0 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXG45976.1 - 0.018 13.8 0.1 0.029 13.2 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 KXG45976.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PGM_PMM_I PF02878.16 KXG45977.1 - 4.5e-36 123.6 0.0 9e-36 122.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KXG45977.1 - 1.3e-23 83.6 0.0 3.2e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KXG45977.1 - 2.4e-15 56.7 0.2 4.4e-15 55.9 0.2 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KXG45977.1 - 3.3e-07 30.4 0.0 8.9e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain FA_desaturase PF00487.24 KXG45978.1 - 1.5e-26 93.8 25.7 2.1e-26 93.3 25.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXG45978.1 - 4.8e-11 42.6 0.0 9.7e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Unstab_antitox PF09720.10 KXG45978.1 - 0.095 12.8 0.3 3 7.9 0.0 2.5 2 0 0 2 2 2 0 Putative addiction module component CUE PF02845.16 KXG45979.1 - 5.8e-06 25.9 0.1 1e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 CUE domain Ribosomal_S10 PF00338.22 KXG45980.1 - 6.2e-26 90.5 0.3 7.3e-26 90.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-CCCH_4 PF18044.1 KXG45981.1 - 1e-09 37.9 3.3 2e-09 37.0 3.3 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KXG45981.1 - 5.2e-07 29.4 2.5 1.1e-06 28.3 2.5 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXG45981.1 - 3.1e-06 27.0 7.1 3.1e-06 27.0 7.1 1.8 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 KXG45981.1 - 0.042 14.5 0.8 0.082 13.6 0.8 1.4 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 KXG45981.1 - 0.15 12.5 4.7 0.32 11.5 4.7 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger ELYS PF13934.6 KXG45982.1 - 5.9e-67 225.9 1.4 7e-67 225.6 1.4 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly Thioredoxin_8 PF13905.6 KXG45982.1 - 0.067 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like SMC_N PF02463.19 KXG45983.1 - 3.3e-74 249.0 12.7 1.2e-73 247.2 12.7 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXG45983.1 - 4.4e-24 85.0 0.0 3.5e-23 82.1 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXG45983.1 - 3.3e-12 46.8 1.0 4.1e-05 23.6 0.0 3.6 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXG45983.1 - 1.1e-09 39.1 5.4 1.1e-09 39.1 5.4 7.2 2 2 2 4 4 4 1 AAA domain DUF3584 PF12128.8 KXG45983.1 - 0.00014 19.6 45.4 0.00014 19.6 45.4 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 KXG45983.1 - 0.00057 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Cob_adeno_trans PF01923.18 KXG45983.1 - 0.0013 18.9 2.1 0.0013 18.9 2.1 6.2 3 2 1 5 5 5 1 Cobalamin adenosyltransferase GAS PF13851.6 KXG45983.1 - 0.0047 16.3 11.2 0.0047 16.3 11.2 7.4 2 2 4 7 7 7 2 Growth-arrest specific micro-tubule binding SbcCD_C PF13558.6 KXG45983.1 - 0.027 14.7 0.0 0.71 10.1 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit BTB_2 PF02214.22 KXG45983.1 - 0.25 11.7 1.4 5.5 7.4 0.1 2.9 2 0 0 2 2 2 0 BTB/POZ domain adh_short_C2 PF13561.6 KXG45984.1 - 5e-28 98.2 0.1 1.7e-26 93.3 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG45984.1 - 4e-19 68.8 0.0 5.1e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG45984.1 - 0.044 13.7 0.2 0.092 12.6 0.2 1.6 1 1 0 1 1 1 0 KR domain p450 PF00067.22 KXG45985.1 - 7e-17 61.3 0.0 8.1e-17 61.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_16 PF00722.21 KXG45986.1 - 9.4e-42 142.5 4.8 1.8e-41 141.5 4.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 p450 PF00067.22 KXG45987.1 - 2.3e-80 270.6 0.0 3e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KXG45987.1 - 5.7e-27 94.7 0.0 8.7e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXG45987.1 - 3.6e-24 85.6 0.0 2.4e-23 82.9 0.0 2.2 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KXG45987.1 - 1.6e-08 35.2 0.0 3.7e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KXG45987.1 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain FMO-like PF00743.19 KXG45988.1 - 8.3e-27 93.8 0.0 1.7e-11 43.3 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXG45988.1 - 5.1e-12 45.6 0.0 0.00017 21.0 0.0 3.1 2 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG45988.1 - 1.1e-10 41.3 2.5 1.4e-07 31.1 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG45988.1 - 2.9e-06 27.4 0.3 0.0038 17.2 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXG45988.1 - 9.4e-06 25.8 0.0 2.8e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXG45988.1 - 2.3e-05 23.7 0.3 0.0044 16.2 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXG45988.1 - 0.0081 15.8 0.8 2.3 7.7 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase IcmF-related PF06761.12 KXG45988.1 - 0.079 12.4 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing Thi4 PF01946.17 KXG45988.1 - 0.081 12.2 0.1 0.21 10.8 0.1 1.6 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.20 KXG45988.1 - 0.099 12.7 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 KXG45989.1 - 1.6e-56 191.5 1.3 1.8e-56 191.3 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG45989.1 - 7.5e-40 136.5 2.0 8.9e-40 136.2 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG45989.1 - 1.4e-10 41.3 2.1 2.1e-10 40.8 2.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXG45989.1 - 0.0094 15.8 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HHH_5 PF14520.6 KXG45989.1 - 0.04 14.5 0.3 0.13 12.9 0.3 2.0 1 1 0 1 1 1 0 Helix-hairpin-helix domain 2-Hacid_dh_C PF02826.19 KXG45989.1 - 0.1 11.9 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1579 PF07617.11 KXG45989.1 - 0.1 12.5 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1579) TrkA_N PF02254.18 KXG45989.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF2673 PF10880.8 KXG45989.1 - 0.2 11.8 0.7 0.52 10.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) Glyco_hydro_43 PF04616.14 KXG45990.1 - 3.9e-36 124.8 0.7 5.2e-36 124.4 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.18 KXG45991.1 - 5.3e-10 38.8 2.6 9.9e-10 37.9 2.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Suc_Fer-like PF06999.12 KXG45992.1 - 5.5e-67 225.4 0.0 6.4e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Glyco_hydro_18 PF00704.28 KXG45993.1 - 4.2e-46 158.1 5.2 4.2e-46 158.1 5.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KXG45993.1 - 9.4e-08 32.4 11.0 9.4e-08 32.4 11.0 3.7 2 2 0 2 2 2 1 Chitin recognition protein LysM PF01476.20 KXG45993.1 - 2.3e-05 24.3 0.0 0.053 13.6 0.1 2.9 2 0 0 2 2 2 2 LysM domain Peripla_BP_7 PF18610.1 KXG45993.1 - 0.063 13.4 0.2 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 Periplasmic binding protein domain DUF4298 PF14131.6 KXG45993.1 - 1.4 8.9 3.6 15 5.6 3.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4298) MraZ PF02381.18 KXG45995.1 - 0.09 12.8 0.0 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like NACHT PF05729.12 KXG45996.1 - 2.6e-08 33.9 0.0 7.5e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain NACHT_N PF17100.5 KXG45996.1 - 5.7e-08 32.9 0.1 2.2e-07 31.0 0.1 2.0 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_16 PF13191.6 KXG45996.1 - 2.7e-07 31.1 1.1 1.9e-06 28.4 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KXG45996.1 - 3.6e-07 30.5 0.0 2e-06 28.1 0.0 2.3 1 0 0 1 1 1 1 AAA domain SH3_1 PF00018.28 KXG45996.1 - 9e-05 22.0 0.0 0.0003 20.3 0.0 2.0 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXG45996.1 - 0.00015 21.6 0.0 0.00038 20.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain ATPase_2 PF01637.18 KXG45996.1 - 0.00048 20.1 0.2 0.0017 18.3 0.0 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KXG45996.1 - 0.0016 18.5 0.3 0.032 14.3 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KXG45996.1 - 0.0032 17.3 0.2 0.0032 17.3 0.2 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KXG45996.1 - 0.0051 16.0 0.5 0.015 14.5 0.1 2.0 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.18 KXG45996.1 - 0.0071 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KXG45996.1 - 0.017 15.5 0.0 0.066 13.6 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KXG45996.1 - 0.043 14.1 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXG45996.1 - 0.11 12.2 0.0 21 4.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain FRG2 PF15315.6 KXG45996.1 - 0.14 12.4 0.3 0.4 10.9 0.3 1.8 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Drc1-Sld2 PF11719.8 KXG45997.1 - 9.7e-115 384.7 30.1 2.2e-114 383.5 30.1 1.5 1 1 0 1 1 1 1 DNA replication and checkpoint protein 2OG-Fe_Oxy_2 PF10014.9 KXG45998.1 - 4.6e-45 153.8 0.2 7.2e-45 153.1 0.2 1.3 1 0 0 1 1 1 1 2OG-Fe dioxygenase zf-RING_2 PF13639.6 KXG45999.1 - 1.1e-07 32.0 11.0 1.7e-07 31.4 11.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXG45999.1 - 8.1e-06 25.6 10.3 1.2e-05 25.0 10.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXG45999.1 - 1.1e-05 25.2 6.5 1.5e-05 24.7 6.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXG45999.1 - 2.6e-05 24.0 11.6 3.9e-05 23.4 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXG45999.1 - 0.00018 21.7 10.0 0.00055 20.2 10.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXG45999.1 - 0.1 12.6 8.3 0.2 11.7 8.3 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXG45999.1 - 0.23 11.5 2.5 0.52 10.4 2.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 KXG45999.1 - 2 8.3 6.4 3.2 7.6 6.4 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 KXG45999.1 - 2.6 7.9 8.1 4.3 7.2 8.1 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_11 PF17123.5 KXG45999.1 - 3.6 7.4 7.0 7.5 6.4 7.0 1.5 1 0 0 1 1 1 0 RING-like zinc finger HAD_SAK_1 PF10307.9 KXG46000.1 - 4.4e-78 261.7 0.0 6.4e-78 261.2 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins XPG_I PF00867.18 KXG46001.1 - 8.6e-24 83.7 0.2 1.7e-23 82.8 0.2 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KXG46001.1 - 8.4e-07 29.4 0.1 1.2e-05 25.7 0.0 2.3 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 KXG46001.1 - 2.9e-05 23.7 0.0 4.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing Tma16 PF11176.8 KXG46002.1 - 4.6e-51 172.5 3.5 5.7e-51 172.2 3.5 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 DUF4777 PF16007.5 KXG46002.1 - 0.00056 20.1 0.2 0.01 16.1 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4777) Cauli_AT PF03233.13 KXG46002.1 - 0.037 13.9 1.0 0.054 13.4 1.0 1.2 1 0 0 1 1 1 0 Aphid transmission protein RNA_polI_A14 PF08203.11 KXG46002.1 - 0.16 12.7 0.8 0.54 11.0 0.3 2.0 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 MAM33 PF02330.16 KXG46003.1 - 6.6e-68 228.8 7.5 7.7e-68 228.6 7.5 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein DNA_primase_S PF01896.19 KXG46004.1 - 3.3e-57 193.4 0.0 4.9e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit DUF5058 PF16481.5 KXG46005.1 - 0.22 11.2 0.4 0.33 10.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) Thr_synth_N PF14821.6 KXG46006.1 - 1.6e-29 101.9 0.0 6.4e-29 100.0 0.0 2.1 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 KXG46006.1 - 1.6e-12 47.4 0.0 7.6e-12 45.2 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1366 PF07104.11 KXG46006.1 - 0.1 12.3 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) ADH_N PF08240.12 KXG46007.1 - 5.4e-24 84.2 5.1 8.3e-24 83.6 5.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG46007.1 - 4.3e-18 65.6 0.0 7.3e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG46007.1 - 7.2e-10 40.0 0.0 1.1e-09 39.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXG46007.1 - 0.0082 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CBM_10 PF02013.16 KXG46007.1 - 0.048 14.1 1.3 0.91 10.0 0.1 2.6 2 0 0 2 2 2 0 Cellulose or protein binding domain AlaDh_PNT_C PF01262.21 KXG46007.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Adaptin_N PF01602.20 KXG46008.1 - 1.4e-138 462.8 4.6 1.8e-138 462.4 4.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXG46008.1 - 1.7e-63 213.5 2.8 5.4e-60 202.1 0.4 2.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXG46008.1 - 4.7e-17 62.2 4.1 1.4e-06 28.6 0.0 6.3 3 2 4 7 7 7 6 HEAT repeats HEAT PF02985.22 KXG46008.1 - 2.2e-12 46.1 3.0 0.023 14.9 0.0 7.0 7 0 0 7 7 7 2 HEAT repeat CLASP_N PF12348.8 KXG46008.1 - 0.00014 21.5 0.6 0.46 10.0 0.0 4.1 3 1 1 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.6 KXG46008.1 - 0.00058 20.3 6.9 0.4 11.3 0.0 5.8 6 1 1 7 7 6 1 HEAT-like repeat DUF2817 PF10994.8 KXG46008.1 - 0.0055 16.2 0.1 0.0098 15.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) RTP1_C1 PF10363.9 KXG46008.1 - 0.0056 16.8 0.8 2 8.6 0.0 4.2 2 2 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KXG46008.1 - 0.0095 16.0 1.3 49 4.2 0.0 5.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 KXG46008.1 - 0.38 10.6 2.0 2 8.3 0.3 2.9 2 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CAAP1 PF15335.6 KXG46008.1 - 0.56 10.8 2.5 0.62 10.7 0.1 2.3 3 0 0 3 3 2 0 Caspase activity and apoptosis inhibitor 1 DEK_C PF08766.11 KXG46009.1 - 0.00062 19.6 0.0 0.0018 18.1 0.0 1.8 1 0 0 1 1 1 1 DEK C terminal domain Evr1_Alr PF04777.13 KXG46010.1 - 6.9e-28 97.1 5.5 6.9e-28 97.1 5.5 1.6 2 0 0 2 2 2 1 Erv1 / Alr family SCP_3 PF17844.1 KXG46010.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial SCP ortholog Coatomer_WDAD PF04053.14 KXG46011.1 - 1.1e-147 492.7 0.0 3.6e-147 491.0 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 KXG46011.1 - 2.3e-107 359.3 0.0 3.2e-107 358.8 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KXG46011.1 - 1.3e-38 130.2 12.4 3.7e-08 33.9 0.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG46011.1 - 1.4e-07 31.7 0.5 1.2 9.5 0.0 6.2 3 3 5 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXG46011.1 - 0.016 13.9 8.1 1.5 7.4 0.2 4.0 3 1 1 4 4 4 0 Nucleoporin Nup120/160 TPR_14 PF13428.6 KXG46011.1 - 5.3 8.1 5.0 42 5.3 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TBCC PF07986.12 KXG46014.1 - 2.6e-32 111.1 0.4 3.8e-32 110.5 0.4 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KXG46014.1 - 7.9e-06 26.3 0.1 1.3e-05 25.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain RTX PF02382.15 KXG46014.1 - 0.085 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein Pro-kuma_activ PF09286.11 KXG46015.1 - 3.8e-37 127.8 1.4 1.8e-36 125.5 0.1 2.7 4 0 0 4 4 4 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXG46015.1 - 5.5e-06 25.9 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Subtilase family CSN8_PSD8_EIF3K PF10075.9 KXG46016.1 - 4.2e-19 69.0 0.0 6.9e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family MFS_1 PF07690.16 KXG46018.1 - 9e-39 133.4 27.3 3.2e-34 118.4 18.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXG46018.1 - 3.3e-05 22.6 22.4 0.00021 20.0 11.7 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_4 PF06779.14 KXG46018.1 - 0.0002 20.8 16.0 0.0062 15.9 9.5 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KXG46018.1 - 0.0003 19.2 6.5 0.00068 18.1 3.0 2.6 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KXG46018.1 - 0.0076 15.2 18.9 0.3 9.9 0.2 3.7 2 1 2 4 4 4 3 MFS_1 like family DUF1917 PF08939.10 KXG46019.1 - 1.8e-86 290.3 0.0 2.8e-86 289.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) EHN PF06441.12 KXG46019.1 - 1.1e-32 112.6 0.5 2.3e-32 111.6 0.0 1.8 2 0 0 2 2 2 1 Epoxide hydrolase N terminus DIOX_N PF14226.6 KXG46019.1 - 3.1e-32 111.8 0.0 5.5e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG46019.1 - 1.1e-20 74.0 0.0 2.6e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_1 PF00561.20 KXG46019.1 - 1.5e-12 47.7 0.4 4.8e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG46019.1 - 0.0011 19.6 1.2 0.0031 18.1 1.2 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Vps51 PF08700.11 KXG46020.1 - 4.3e-27 94.0 0.0 9.9e-27 92.9 0.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 KXG46020.1 - 0.026 14.7 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Dor1 PF04124.12 KXG46020.1 - 0.1 11.3 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Dor1-like family RMI1_N PF08585.12 KXG46021.1 - 7.5e-64 215.4 0.0 8.6e-64 215.3 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein TPR_16 PF13432.6 KXG46022.1 - 8.1e-25 87.2 38.5 4.2e-05 24.1 0.8 12.0 10 2 2 12 12 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 KXG46022.1 - 1.3e-24 84.9 22.2 0.0024 17.6 0.0 11.9 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 KXG46022.1 - 5.8e-23 79.1 44.0 0.0017 18.3 0.0 15.3 16 0 0 16 16 15 6 Tetratricopeptide repeat TPR_14 PF13428.6 KXG46022.1 - 2.9e-21 74.3 42.2 0.00018 22.0 0.1 15.6 11 4 5 16 16 15 5 Tetratricopeptide repeat TPR_17 PF13431.6 KXG46022.1 - 1.2e-20 72.4 6.5 0.37 11.3 0.0 12.7 12 1 0 12 12 12 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXG46022.1 - 3.7e-18 65.8 29.2 0.0017 18.8 0.7 10.1 10 1 1 11 11 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXG46022.1 - 1.2e-17 62.6 33.8 0.013 15.7 0.0 12.8 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_11 PF13414.6 KXG46022.1 - 3e-16 58.8 10.3 0.074 12.8 0.0 9.6 9 1 1 10 10 9 4 TPR repeat TPR_6 PF13174.6 KXG46022.1 - 2.5e-09 37.2 27.3 0.0012 19.3 0.1 11.5 13 0 0 13 13 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXG46022.1 - 5.1e-09 35.5 18.0 0.0032 17.4 0.0 8.7 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXG46022.1 - 3.4e-07 30.5 2.4 3.4e-05 24.0 1.1 11.1 11 2 0 11 11 10 2 Tetratricopeptide repeat TPR_22 PF18833.1 KXG46022.1 - 7.9e-07 29.1 0.0 2.7e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG46022.1 - 0.00013 22.2 15.2 0.19 12.0 0.6 6.2 6 0 0 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.9 KXG46022.1 - 0.002 17.9 1.9 2.5 7.7 0.1 4.1 3 1 1 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_9 PF13371.6 KXG46022.1 - 0.0034 17.5 19.8 0.45 10.7 0.0 6.7 6 1 1 7 7 6 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KXG46022.1 - 0.0078 15.9 0.2 2.6 7.7 0.2 3.1 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) PknG_TPR PF16918.5 KXG46022.1 - 0.079 11.7 3.0 4.8 5.8 0.1 3.0 3 0 0 3 3 3 0 Protein kinase G tetratricopeptide repeat ANAPC5 PF12862.7 KXG46022.1 - 0.08 13.0 4.6 0.82 9.8 0.5 4.1 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 DrrA_P4M PF14860.6 KXG46022.1 - 0.091 12.6 0.2 1.9 8.4 0.1 2.6 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain TPR_10 PF13374.6 KXG46022.1 - 2.5 8.1 30.1 1.7 8.7 0.3 7.9 8 0 0 8 8 7 0 Tetratricopeptide repeat BTAD PF03704.17 KXG46022.1 - 3.7 8.0 16.0 1.1 9.7 0.2 5.1 4 1 1 5 5 4 0 Bacterial transcriptional activator domain Glyco_hydro_5_C PF18564.1 KXG46023.1 - 2.2e-21 76.2 0.0 4.8e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Xpo1 PF08389.12 KXG46023.1 - 5.5e-11 42.7 0.3 6.2e-05 23.1 0.0 3.2 2 0 0 2 2 2 2 Exportin 1-like protein Cellulase PF00150.18 KXG46023.1 - 1.2e-07 31.5 0.3 2e-06 27.5 0.1 2.3 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) HEAT_2 PF13646.6 KXG46023.1 - 0.019 15.3 0.7 0.13 12.7 0.1 2.6 2 0 0 2 2 2 0 HEAT repeats GRIM-19 PF06212.12 KXG46024.1 - 2.6e-23 82.4 0.7 7.9e-23 80.9 0.7 1.7 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.21 KXG46025.1 - 8.1e-27 94.2 0.0 5.7e-26 91.4 0.0 2.2 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase VID27 PF08553.10 KXG46026.1 - 9.2e-195 646.6 0.2 1.2e-194 646.2 0.2 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KXG46026.1 - 3.3e-75 251.7 0.1 3.3e-75 251.7 0.1 2.9 3 1 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 KXG46026.1 - 3.4e-48 162.5 2.2 1.3e-47 160.6 1.5 2.2 2 0 0 2 2 2 1 VID27 PH-like domain UPF0149 PF03695.13 KXG46026.1 - 0.0053 17.1 4.8 0.012 15.9 3.9 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0149) Nop14 PF04147.12 KXG46026.1 - 1.2 7.3 13.9 2 6.5 13.9 1.2 1 0 0 1 1 1 0 Nop14-like family Dynamin_M PF01031.20 KXG46028.1 - 5.5e-20 71.7 0.6 7e-19 68.1 0.1 2.6 2 1 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KXG46028.1 - 4.2e-19 69.2 0.0 7.9e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Fungal_trans PF04082.18 KXG46029.1 - 1.4e-16 60.3 0.1 2.4e-16 59.6 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF374 PF04028.13 KXG46029.1 - 0.031 13.8 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF374) MFS_1 PF07690.16 KXG46030.1 - 1.1e-42 146.3 39.6 1.1e-42 146.3 39.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG46030.1 - 1.5e-08 34.0 30.3 6.5e-08 31.9 30.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 KXG46030.1 - 0.048 12.0 4.9 0.065 11.6 4.4 1.6 1 1 0 1 1 1 0 Transmembrane secretion effector OATP PF03137.20 KXG46030.1 - 4.4 5.5 17.8 0.71 8.1 6.0 3.7 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TLD PF07534.16 KXG46031.1 - 1.8e-24 86.5 0.0 1.3e-14 54.6 0.0 2.3 2 0 0 2 2 2 2 TLD JAB PF01398.21 KXG46032.1 - 6.9e-15 55.1 0.0 1.5e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KXG46032.1 - 8.1e-11 42.1 0.7 1.4e-10 41.4 0.7 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KXG46032.1 - 7.9e-05 22.4 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RrnaAD PF00398.20 KXG46033.1 - 1.7e-07 30.6 0.0 2.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Pkinase PF00069.25 KXG46034.1 - 4e-14 52.6 0.0 9.1e-14 51.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG46034.1 - 2.9e-05 23.5 0.0 4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXG46034.1 - 0.01 15.8 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXG46034.1 - 0.043 12.6 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KXG46034.1 - 0.088 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Polyketide_cyc2 PF10604.9 KXG46035.1 - 1e-06 29.1 11.0 4.1e-05 23.9 11.0 2.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KXG46035.1 - 0.0001 22.5 0.1 0.00019 21.7 0.1 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 KXG46035.1 - 0.23 11.7 4.9 0.31 11.3 1.2 2.5 2 1 1 3 3 3 0 Activator of Hsp90 ATPase homolog 1-like protein N-SET PF11764.8 KXG46036.1 - 4.2 7.4 12.0 6.5 6.8 12.0 1.2 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N Amidase PF01425.21 KXG46037.1 - 7.7e-90 302.0 0.0 1.6e-87 294.3 0.0 2.7 1 1 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.8 KXG46037.1 - 4e-08 32.5 1.2 4.6e-07 29.0 1.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG46037.1 - 0.00033 20.7 6.7 0.00033 20.7 6.7 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Iso_dh PF00180.20 KXG46039.1 - 5.9e-65 219.7 0.0 7.2e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase FTHFS PF01268.19 KXG46040.1 - 4.2e-252 837.3 0.1 6.1e-252 836.8 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KXG46040.1 - 5.1e-66 220.9 0.9 1.1e-65 219.8 0.9 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KXG46040.1 - 2.8e-37 127.5 0.4 6.7e-37 126.3 0.4 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KXG46040.1 - 0.018 14.0 0.1 0.035 13.0 0.1 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family GTP_EFTU PF00009.27 KXG46040.1 - 0.035 13.6 0.3 0.092 12.3 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain WD40 PF00400.32 KXG46041.1 - 1.5e-27 95.3 1.1 1e-08 35.7 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG46041.1 - 2.5e-12 46.9 0.1 0.0039 17.5 0.2 5.7 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KXG46041.1 - 6.9e-06 25.8 0.3 3e-05 23.7 0.3 2.0 1 1 0 1 1 1 1 PQQ-like domain WD40_like PF17005.5 KXG46041.1 - 0.001 18.5 0.0 0.016 14.5 0.0 2.7 2 1 2 4 4 4 1 WD40-like domain Gmad1 PF10647.9 KXG46041.1 - 0.0062 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KXG46041.1 - 0.0085 14.8 0.1 0.013 14.2 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXG46041.1 - 0.026 13.5 0.8 20 4.0 0.0 3.6 2 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein S-methyl_trans PF02574.16 KXG46042.1 - 6.4e-43 147.5 0.0 7.2e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase MBF1 PF08523.10 KXG46043.1 - 1.3e-23 83.2 0.8 2.4e-23 82.4 0.8 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KXG46043.1 - 4.2e-09 36.3 0.1 7.2e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KXG46043.1 - 0.00025 21.3 0.0 0.00053 20.3 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain SH3_1 PF00018.28 KXG46044.1 - 3.9e-16 58.4 0.1 5.9e-16 57.8 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXG46044.1 - 1.6e-13 50.3 0.1 3.3e-13 49.3 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KXG46044.1 - 3.1e-08 33.2 0.0 4.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Ank_2 PF12796.7 KXG46045.1 - 1.5e-16 60.7 0.0 1.6e-09 38.2 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG46045.1 - 5.5e-11 42.8 0.0 0.0025 18.4 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG46045.1 - 1.1e-10 40.8 2.0 1 10.2 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KXG46045.1 - 1.3e-09 38.1 0.0 0.096 13.0 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXG46045.1 - 3.6e-07 30.3 0.0 5.2 7.7 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat AIM24 PF01987.17 KXG46046.1 - 2.2e-53 181.0 0.1 2.8e-53 180.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 eIF-5_eIF-2B PF01873.17 KXG46047.1 - 4.7e-40 136.1 0.3 7.3e-40 135.5 0.3 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KXG46047.1 - 0.17 11.4 1.3 0.33 10.5 1.3 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 KXG46047.1 - 1.3 9.4 7.4 1.1 9.7 0.4 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain RRM_1 PF00076.22 KXG46050.1 - 4e-20 71.4 0.0 5.4e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXG46050.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 KXG46050.1 - 0.22 11.4 0.0 0.45 10.4 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif ChaC PF04752.12 KXG46051.1 - 3.4e-55 186.9 0.0 4.1e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein DUF3433 PF11915.8 KXG46052.1 - 7.4e-36 122.5 13.2 1.6e-19 70.2 1.7 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) COX2_TM PF02790.15 KXG46052.1 - 0.21 11.8 7.5 3.9 7.7 0.3 3.2 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain adh_short PF00106.25 KXG46053.1 - 2.9e-18 66.0 0.0 6.9e-17 61.5 0.1 2.6 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG46053.1 - 3.3e-11 43.2 0.0 5.6e-09 35.9 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG46053.1 - 1.3e-07 31.7 0.0 2.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Ank_2 PF12796.7 KXG46054.1 - 6.2e-75 247.8 34.4 2.8e-15 56.7 0.7 7.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG46054.1 - 1.4e-49 165.8 2.3 5.5e-08 33.2 0.0 8.8 5 2 3 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 KXG46054.1 - 1.9e-41 138.7 21.0 0.0046 17.3 0.0 12.7 12 0 0 12 12 12 10 Ankyrin repeat Ank_3 PF13606.6 KXG46054.1 - 6.5e-29 96.8 8.4 0.57 10.9 0.1 12.6 13 0 0 13 13 11 7 Ankyrin repeat Ank_5 PF13857.6 KXG46054.1 - 1.4e-22 79.4 10.5 0.00032 20.9 0.1 8.5 3 2 4 9 9 9 7 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KXG46054.1 - 2.3e-11 43.5 0.0 4.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 KXG46054.1 - 3.9e-06 26.9 0.0 8.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain RelB_N PF18506.1 KXG46054.1 - 0.0015 18.3 12.0 19 5.2 0.0 6.5 8 0 0 8 8 7 0 RelB Antitoxin alpha helical domain AAA_16 PF13191.6 KXG46054.1 - 0.0022 18.4 0.0 0.011 16.1 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain GLF PF03275.13 KXG46054.1 - 0.0046 16.7 0.0 55 3.4 0.0 4.8 2 1 4 6 6 6 0 UDP-galactopyranose mutase AAA_22 PF13401.6 KXG46054.1 - 0.036 14.3 0.0 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF1722 PF08349.11 KXG46054.1 - 0.045 14.0 0.0 0.27 11.6 0.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1722) CCAP PF11105.8 KXG46054.1 - 0.16 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a LcrV PF04792.12 KXG46054.1 - 0.22 10.7 0.5 2.9 7.1 0.0 2.8 2 1 1 3 3 3 0 V antigen (LcrV) protein EF-hand_1 PF00036.32 KXG46055.1 - 7.7e-22 75.2 0.2 7.4e-08 31.4 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KXG46055.1 - 1.4e-19 68.2 0.4 0.0001 21.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KXG46055.1 - 4.6e-18 65.4 0.0 2.8e-08 34.1 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KXG46055.1 - 1.7e-17 63.0 0.1 2.2e-08 33.8 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KXG46055.1 - 1.4e-14 52.8 0.5 0.00075 18.9 0.0 3.8 4 0 0 4 4 4 3 EF hand F-box-like PF12937.7 KXG46056.1 - 0.0003 20.6 5.7 0.0019 18.1 5.7 2.4 1 1 0 1 1 1 1 F-box-like Cytokin_check_N PF10407.9 KXG46056.1 - 0.0016 18.3 0.0 0.0036 17.2 0.0 1.6 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus MFS_1 PF07690.16 KXG46057.1 - 3.9e-48 164.2 58.5 3.9e-48 164.2 58.5 2.9 2 2 1 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG46057.1 - 1.3e-23 83.3 13.9 2.1e-23 82.6 13.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXG46057.1 - 2.4e-12 46.5 15.2 2.4e-12 46.5 15.2 3.1 2 2 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KXG46057.1 - 0.0067 14.8 27.4 0.0083 14.5 2.6 4.2 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Ribosomal_L35Ae PF01247.18 KXG46060.1 - 4.6e-43 145.3 0.3 5.2e-43 145.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KXG46060.1 - 0.00033 20.8 0.1 0.19 12.0 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.9 KXG46060.1 - 0.014 15.2 1.0 0.13 12.0 0.1 2.2 1 1 1 2 2 2 0 Putative transposon-encoded protein (DUF2080) G6PD_C PF02781.16 KXG46061.1 - 2.4e-115 384.7 0.0 3.7e-115 384.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KXG46061.1 - 1e-60 205.4 0.1 1.7e-60 204.7 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MFS_2 PF13347.6 KXG46061.1 - 2e-08 33.2 9.4 2e-08 33.2 9.4 2.0 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 KXG46061.1 - 0.00037 19.5 0.0 0.0014 17.6 0.0 1.7 1 1 0 1 1 1 1 MFS_1 like family DJ-1_PfpI PF01965.24 KXG46062.1 - 3e-09 36.9 0.0 6.2e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KXG46062.1 - 0.0018 18.0 0.0 0.0051 16.5 0.0 1.8 1 1 0 1 1 1 1 ThiJ/PfpI family-like DUF1708 PF08101.11 KXG46063.1 - 8.4e-174 578.8 0.0 1.3e-173 578.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.27 KXG46063.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 RhoGAP domain SRF-TF PF00319.18 KXG46064.1 - 1.2e-23 82.3 0.2 1.8e-23 81.7 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) GFA PF04828.14 KXG46065.1 - 9.3e-25 86.8 0.6 1.2e-24 86.4 0.6 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme SIMPL PF04402.14 KXG46066.1 - 1.2e-18 68.3 0.0 1.4e-18 68.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Aminotran_1_2 PF00155.21 KXG46067.1 - 9.9e-41 140.1 0.0 1.2e-40 139.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 KXG46067.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Ank_2 PF12796.7 KXG46068.1 - 2.5e-39 133.7 2.8 9.4e-14 51.8 0.1 4.4 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG46068.1 - 1.9e-34 113.8 0.5 5.1e-05 23.3 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KXG46068.1 - 1.1e-31 108.5 5.4 2.7e-05 24.4 0.1 7.9 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KXG46068.1 - 1.5e-28 97.9 1.0 0.0012 19.2 0.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 KXG46068.1 - 5.1e-28 97.1 2.9 2.7e-05 24.6 0.0 6.5 2 2 4 6 6 6 6 Ankyrin repeats (many copies) DUF1843 PF08898.10 KXG46068.1 - 0.063 13.8 0.1 15 6.2 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF4265 PF14085.6 KXG46068.1 - 0.088 12.8 0.0 2.8 7.9 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4265) BATS PF06968.13 KXG46068.1 - 0.12 12.5 0.0 2 8.6 0.0 2.3 2 0 0 2 2 2 0 Biotin and Thiamin Synthesis associated domain DUF5049 PF16468.5 KXG46068.1 - 0.17 11.8 0.0 8.8 6.3 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5049) Trehalase_Ca-bi PF07492.11 KXG46068.1 - 0.19 11.5 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain zf-MYND PF01753.18 KXG46069.1 - 1.2e-08 34.9 8.9 1.2e-08 34.9 8.9 1.8 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 KXG46069.1 - 0.59 10.3 10.2 16 5.7 8.9 3.0 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 PAPS_reduct PF01507.19 KXG46070.1 - 2.6e-41 141.5 0.0 3.8e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.7 KXG46071.1 - 7e-23 82.0 0.0 1.1e-22 81.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXG46071.1 - 1.2e-17 64.9 0.6 1.9e-17 64.3 0.6 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXG46071.1 - 2.8e-10 40.4 0.4 1.7e-08 34.6 0.0 2.9 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXG46071.1 - 3.6e-07 30.4 0.2 4.3e-06 26.9 0.2 2.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KXG46071.1 - 0.002 17.6 0.0 0.048 13.1 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase S6PP PF05116.13 KXG46071.1 - 0.1 12.1 0.1 0.97 8.9 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase DUF705 PF05152.12 KXG46071.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) LIAS_N PF16881.5 KXG46072.1 - 7.2e-26 90.7 0.0 1.4e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KXG46072.1 - 1.3e-15 58.1 0.0 2.2e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily WD40 PF00400.32 KXG46074.1 - 1e-08 35.6 10.7 0.00015 22.5 0.2 5.3 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG46074.1 - 6e-05 23.3 0.0 6.5 7.1 0.0 4.3 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KXG46074.1 - 0.00067 19.3 0.7 0.002 17.7 0.3 2.0 2 1 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.6 KXG46074.1 - 0.039 14.5 2.4 6.6 7.4 0.0 3.9 3 1 1 4 4 4 0 PQQ-like domain WD40_alt PF14077.6 KXG46074.1 - 0.068 13.0 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif T6PP_N PF18572.1 KXG46074.1 - 0.11 12.3 0.8 0.22 11.4 0.8 1.4 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain FAM76 PF16046.5 KXG46074.1 - 0.13 11.6 2.3 0.18 11.1 2.3 1.2 1 0 0 1 1 1 0 FAM76 protein TMF_TATA_bd PF12325.8 KXG46074.1 - 0.13 12.4 9.1 1.2 9.4 8.8 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.9 KXG46074.1 - 2 7.4 6.4 3.2 6.8 6.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KXG46074.1 - 2.7 8.5 12.2 4.2 7.9 12.2 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Cep57_CLD_2 PF14197.6 KXG46074.1 - 5.2 7.2 11.7 9.5 6.4 11.7 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DeoC PF01791.9 KXG46075.1 - 2.4e-21 76.5 1.1 3.1e-21 76.1 1.1 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase SelK_SelG PF10961.8 KXG46076.1 - 1.9e-05 25.2 16.3 0.00018 22.1 16.3 2.0 1 1 0 1 1 1 1 Selenoprotein SelK_SelG TP_methylase PF00590.20 KXG46077.1 - 2.7e-48 164.7 0.0 6.8e-48 163.4 0.0 1.6 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KXG46077.1 - 9.2e-16 58.2 0.0 2.2e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KXG46077.1 - 4.7e-12 45.4 0.1 8.5e-08 31.7 0.0 2.9 3 0 0 3 3 3 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KXG46077.1 - 7.1e-08 31.8 0.0 1.6e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central DUF498 PF04430.14 KXG46077.1 - 0.0095 16.0 0.0 0.17 11.9 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF498/DUF598) preATP-grasp_3 PF18301.1 KXG46077.1 - 0.11 12.8 0.0 0.42 10.9 0.0 2.0 2 0 0 2 2 2 0 pre ATP-grasp 3 domain PCI PF01399.27 KXG46078.1 - 3.1e-21 75.9 0.6 1.2e-20 73.9 0.0 2.3 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KXG46078.1 - 1e-15 57.5 2.0 2.9e-15 56.1 2.0 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain ERp29 PF07749.12 KXG46078.1 - 1.6 9.6 7.5 0.89 10.5 0.1 3.4 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain FSH1 PF03959.13 KXG46079.1 - 6.8e-74 248.1 0.0 8.3e-74 247.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXG46079.1 - 4.9e-07 30.6 2.8 1e-06 29.5 2.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXG46079.1 - 0.012 15.5 0.0 5.1 6.8 0.1 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase HpaB PF03241.13 KXG46079.1 - 0.06 12.4 0.0 0.51 9.4 0.0 2.0 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Hydrolase_4 PF12146.8 KXG46079.1 - 0.063 12.5 0.1 0.28 10.4 0.0 2.1 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXG46079.1 - 0.17 11.5 0.0 0.41 10.3 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Ribosomal_S27e PF01667.17 KXG46082.1 - 9.9e-29 98.8 6.7 1.3e-28 98.5 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2HC5 PF06221.13 KXG46082.1 - 0.29 11.2 6.3 2 8.4 4.2 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type CDP-OH_P_transf PF01066.21 KXG46083.1 - 2e-17 63.7 0.1 2e-17 63.7 0.1 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3341 PF11821.8 KXG46083.1 - 5.5 6.6 7.3 7.2 6.2 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) NIPSNAP PF07978.13 KXG46084.1 - 7.8e-42 141.7 0.5 3.4e-28 97.9 0.1 2.5 2 0 0 2 2 2 2 NIPSNAP Putative_PNPOx PF01243.20 KXG46085.1 - 2.8e-12 46.7 0.0 6.8e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KXG46085.1 - 0.0049 16.9 0.0 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase BPL_LplA_LipB PF03099.19 KXG46086.1 - 5.8e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ras PF00071.22 KXG46087.1 - 1.7e-50 170.8 0.0 2e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXG46087.1 - 1.4e-19 70.5 0.0 2.6e-19 69.6 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG46087.1 - 3.8e-08 33.0 0.0 4.8e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXG46087.1 - 0.017 14.5 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KXG46087.1 - 0.032 13.6 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KXG46087.1 - 0.067 12.3 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit PCI PF01399.27 KXG46088.1 - 1.2e-19 70.7 0.1 3.4e-19 69.3 0.1 1.8 1 0 0 1 1 1 1 PCI domain PriX PF18689.1 KXG46088.1 - 0.49 10.8 2.5 3.3 8.1 0.3 2.9 3 0 0 3 3 3 0 Primase X DUF3116 PF11313.8 KXG46088.1 - 4.5 7.2 6.7 8.8 6.3 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3116) Peptidase_C65 PF10275.9 KXG46089.1 - 8e-50 169.6 0.0 9.7e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain DJ-1_PfpI PF01965.24 KXG46090.1 - 1.3e-15 57.6 0.0 1.7e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 KXG46090.1 - 0.027 14.2 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Sugar_tr PF00083.24 KXG46091.1 - 4.8e-121 404.8 14.2 7.4e-121 404.1 14.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG46091.1 - 2e-23 82.9 59.1 9.1e-19 67.6 31.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG46091.1 - 7.5e-05 21.3 1.1 7.5e-05 21.3 1.1 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 KXG46092.1 - 3.8e-28 98.3 0.1 5.9e-28 97.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ELP6 PF09807.9 KXG46093.1 - 1.1e-14 54.5 0.0 2.1e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 Elongation complex protein 6 ATPase PF06745.13 KXG46093.1 - 0.019 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 KaiC Ribosomal_L37e PF01907.19 KXG46094.1 - 6.7e-28 96.6 12.1 1.3e-27 95.7 12.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e CytoC_RC PF02276.18 KXG46094.1 - 0.0022 17.4 0.1 0.0025 17.3 0.1 1.1 1 0 0 1 1 1 1 Photosynthetic reaction centre cytochrome C subunit DZR PF12773.7 KXG46094.1 - 0.012 15.6 1.7 0.023 14.7 1.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 KXG46094.1 - 0.084 12.9 0.6 0.11 12.5 0.6 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF35_N PF12172.8 KXG46094.1 - 0.14 12.1 2.4 0.28 11.1 2.4 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-ribbon_3 PF13248.6 KXG46094.1 - 0.37 10.3 3.7 1.5 8.4 3.7 1.9 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KXG46094.1 - 0.66 9.8 4.4 14 5.6 0.6 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DUF2688 PF10892.8 KXG46094.1 - 0.86 9.1 5.1 18 4.9 4.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) zf-HYPF PF07503.12 KXG46094.1 - 2.4 8.0 6.0 15 5.5 5.3 2.4 1 1 1 2 2 2 0 HypF finger DNA_RNApol_7kD PF03604.13 KXG46094.1 - 3 7.6 10.4 10 5.9 0.1 3.1 2 1 1 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Slu7 PF11708.8 KXG46095.1 - 9e-82 274.8 14.5 9e-82 274.8 14.5 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KXG46095.1 - 0.033 13.9 0.6 0.073 12.8 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle HpaB_N PF11794.8 KXG46095.1 - 0.13 11.9 1.9 2.3 7.8 0.0 2.3 1 1 1 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal eIF3g PF12353.8 KXG46095.1 - 8.7 6.8 11.0 0.18 12.2 0.5 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G DNA_pol_B PF00136.21 KXG46096.1 - 8.2e-105 351.2 0.0 1.1e-104 350.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KXG46096.1 - 2.1e-22 79.7 0.0 8.1e-13 48.2 0.0 2.5 2 1 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KXG46096.1 - 9.2e-17 61.3 5.1 9.2e-17 61.3 5.1 2.2 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta RdRP PF05183.12 KXG46097.1 - 1.9e-183 611.3 0.0 2.8e-183 610.7 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF4472 PF14739.6 KXG46098.1 - 0.011 16.4 1.5 0.011 16.4 1.5 4.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4472) SpecificRecomb PF10136.9 KXG46098.1 - 0.015 13.6 0.0 0.015 13.6 0.0 3.1 2 1 1 3 3 3 0 Site-specific recombinase DUF717 PF05338.12 KXG46098.1 - 0.15 12.2 1.6 3.3 7.9 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF717) DUF3138 PF11336.8 KXG46098.1 - 7.1 5.1 6.2 10 4.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Ribonuc_L-PSP PF01042.21 KXG46099.1 - 5.1e-19 68.5 0.0 6.1e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.16 KXG46100.1 - 5e-32 111.2 32.8 5e-32 111.2 32.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Corona_6B_7B PF03262.13 KXG46100.1 - 0.067 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Coronavirus 6B/7B protein FAD-oxidase_C PF02913.19 KXG46101.1 - 1.3e-65 221.5 0.0 1.7e-65 221.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXG46101.1 - 2.4e-35 121.3 0.0 4.5e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Fungal_trans PF04082.18 KXG46102.1 - 7.6e-12 44.8 0.1 2.2e-11 43.3 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.13 KXG46103.1 - 1.1e-22 80.7 0.1 2.6e-22 79.6 0.1 1.6 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KXG46103.1 - 1.5e-15 57.6 0.0 4.9e-15 55.9 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXG46103.1 - 3.7e-07 30.4 0.1 1.4e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KXG46103.1 - 1.7e-05 25.3 0.3 9.1e-05 22.9 0.1 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KXG46103.1 - 0.034 14.3 0.4 0.079 13.1 0.1 1.9 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 KXG46103.1 - 0.062 12.4 1.0 0.3 10.2 0.0 2.3 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein DXP_reductoisom PF02670.16 KXG46103.1 - 0.063 14.0 0.8 0.15 12.8 0.2 2.1 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Shikimate_DH PF01488.20 KXG46103.1 - 0.091 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KR PF08659.10 KXG46103.1 - 0.12 12.2 0.0 0.68 9.8 0.0 2.0 2 0 0 2 2 2 0 KR domain Semialdhyde_dhC PF02774.18 KXG46104.1 - 2.6e-35 122.2 0.0 3.4e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KXG46104.1 - 1.3e-29 103.0 0.0 3.1e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXG46104.1 - 0.031 14.5 0.1 0.2 11.9 0.0 2.2 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Ribosomal_S4e PF00900.20 KXG46105.1 - 9.3e-38 128.0 0.1 1.8e-37 127.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KXG46105.1 - 1.2e-24 85.7 0.0 2e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KXG46105.1 - 8.6e-17 61.0 5.8 1.6e-16 60.1 5.8 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KXG46105.1 - 6.9e-07 28.9 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KXG46105.1 - 0.0029 17.5 1.9 0.0029 17.5 1.9 2.9 3 0 0 3 3 3 1 KOW motif RasGEF PF00617.19 KXG46106.1 - 5.3e-08 33.3 0.0 1.3e-07 32.0 0.0 1.7 1 1 0 1 1 1 1 RasGEF domain Myb_DNA-bind_6 PF13921.6 KXG46108.1 - 7.6e-18 64.5 0.0 1.3e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXG46108.1 - 1.5e-15 57.1 0.3 1.8e-08 34.5 0.1 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 KXG46108.1 - 9.8e-05 22.4 0.0 0.13 12.3 0.0 2.5 2 1 0 2 2 2 2 SLIDE PX PF00787.24 KXG46109.1 - 1.2e-27 96.1 0.2 1.5e-27 95.8 0.2 1.1 1 0 0 1 1 1 1 PX domain DUF4246 PF14033.6 KXG46110.1 - 3.2e-38 132.0 0.0 3.5e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) WD40 PF00400.32 KXG46111.1 - 5.3e-18 65.0 18.9 0.00088 20.0 0.4 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 KXG46111.1 - 3.8e-05 22.4 1.9 0.28 9.7 0.0 3.9 2 1 2 4 4 4 2 Cytochrome D1 heme domain PPARgamma_N PF12577.8 KXG46111.1 - 0.019 15.6 2.7 7.4 7.3 0.1 3.0 2 1 0 2 2 2 0 PPAR gamma N-terminal region ANAPC4_WD40 PF12894.7 KXG46111.1 - 0.075 13.3 0.0 2.5 8.4 0.0 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXG46111.1 - 0.1 11.2 0.0 0.19 10.3 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KXG46111.1 - 0.19 12.2 2.9 5.2 7.7 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain SecE PF00584.20 KXG46112.1 - 3.3e-15 55.7 0.0 4.1e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_1 PF00076.22 KXG46113.1 - 0.00014 21.6 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GDWWSH PF15667.5 KXG46114.1 - 0.025 14.0 0.3 0.044 13.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function with motif GDWWSH Ribosomal_L21e PF01157.18 KXG46115.1 - 5.7e-46 154.5 4.0 5.7e-46 154.5 4.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e CEP1-DNA_bind PF09287.10 KXG46115.1 - 0.063 12.9 0.2 0.073 12.7 0.2 1.2 1 0 0 1 1 1 0 CEP-1, DNA binding S4 PF01479.25 KXG46116.1 - 2e-12 46.6 0.5 2e-12 46.6 0.5 2.3 3 0 0 3 3 3 1 S4 domain OmpH PF03938.14 KXG46117.1 - 0.034 14.5 10.2 1.1 9.6 3.4 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 KXG46117.1 - 0.23 10.8 9.8 0.45 9.8 9.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2721 PF11026.8 KXG46117.1 - 0.43 10.5 1.6 1.1 9.2 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) ABC_tran_CTD PF16326.5 KXG46117.1 - 0.45 10.8 16.8 0.13 12.5 1.7 4.3 3 2 2 5 5 5 0 ABC transporter C-terminal domain Prefoldin PF02996.17 KXG46117.1 - 0.72 9.8 7.6 0.59 10.1 1.2 3.2 2 2 1 3 3 3 0 Prefoldin subunit Fez1 PF06818.15 KXG46117.1 - 3 8.2 15.9 27 5.1 15.9 2.1 1 1 0 1 1 1 0 Fez1 DOPA_dioxygen PF08883.11 KXG46119.1 - 3.1e-40 136.7 0.0 4e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Vps62 PF06101.11 KXG46120.1 - 2.5e-12 45.9 0.2 3.6e-12 45.4 0.2 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Septin PF00735.18 KXG46121.1 - 8.5e-36 123.7 0.0 3.5e-14 52.7 0.0 3.1 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.23 KXG46121.1 - 7.1e-05 22.9 0.0 0.0002 21.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KXG46121.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 KXG46121.1 - 0.047 13.8 0.3 0.25 11.4 0.0 2.3 2 1 0 2 2 2 0 Dynamin family G-alpha PF00503.20 KXG46121.1 - 0.076 12.2 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.6 KXG46121.1 - 0.08 13.3 0.0 0.2 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Annexin PF00191.20 KXG46122.1 - 4.1e-13 49.2 3.5 4.4e-05 23.5 0.0 4.2 4 0 0 4 4 4 3 Annexin Av_adeno_fibre PF06536.11 KXG46124.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Avian adenovirus fibre, N-terminal Fig1 PF12351.8 KXG46126.1 - 1.4e-10 41.4 0.1 1.4e-10 41.4 0.1 1.7 1 1 1 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 KXG46126.1 - 7.6e-07 29.0 0.0 1.7e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 SUR7/PalI family Glucos_trans_II PF14264.6 KXG46126.1 - 0.01 15.2 2.7 0.028 13.8 2.7 1.6 1 1 0 1 1 1 0 Glucosyl transferase GtrII DUF2207 PF09972.9 KXG46126.1 - 0.012 14.4 0.0 0.17 10.6 0.0 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Acyl_transf_3 PF01757.22 KXG46126.1 - 0.075 12.1 5.3 0.04 13.0 2.6 1.9 2 1 0 2 2 2 0 Acyltransferase family Intg_mem_TP0381 PF09529.10 KXG46126.1 - 0.35 10.3 5.3 0.21 11.1 1.0 2.2 2 0 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) 60KD_IMP PF02096.20 KXG46126.1 - 0.39 10.6 2.4 6.7 6.6 0.0 2.4 3 0 0 3 3 3 0 60Kd inner membrane protein Wzy_C_2 PF11846.8 KXG46126.1 - 0.57 10.1 2.4 18 5.2 0.1 2.4 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal DUF3611 PF12263.8 KXG46126.1 - 2.9 7.8 9.2 0.59 10.0 5.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) CopD PF05425.13 KXG46126.1 - 6.4 7.2 11.7 34 4.9 8.4 2.7 2 1 0 2 2 2 0 Copper resistance protein D DUF5127 PF17168.4 KXG46127.1 - 2.1e-85 286.1 4.0 3.3e-85 285.5 4.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KXG46127.1 - 4.9e-80 267.2 0.6 4.9e-80 267.2 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KXG46127.1 - 1.4e-67 227.3 0.3 1.4e-67 227.3 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KXG46127.1 - 4.4e-07 29.4 0.0 1.6e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Bac_rhamnosid6H PF17389.2 KXG46127.1 - 0.0062 15.8 0.4 0.018 14.3 0.3 1.7 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Peptidase_M20 PF01546.28 KXG46128.1 - 7.8e-29 100.9 0.0 2.1e-28 99.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXG46128.1 - 1e-11 44.7 0.0 2.2e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXG46128.1 - 0.034 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 WSC PF01822.19 KXG46129.1 - 1.8e-16 60.1 9.0 3.9e-16 59.0 9.0 1.6 1 0 0 1 1 1 1 WSC domain GRDP-like PF07173.12 KXG46130.1 - 1.4e-17 64.7 0.1 3.9e-15 56.8 0.0 2.5 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like WD40 PF00400.32 KXG46131.1 - 2.8e-36 122.9 19.2 1.3e-05 25.9 1.2 7.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Ank_2 PF12796.7 KXG46131.1 - 2.3e-34 117.8 0.0 1.9e-11 44.4 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG46131.1 - 7.5e-25 84.3 0.0 0.0002 21.5 0.0 7.9 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KXG46131.1 - 9.9e-25 85.9 0.6 8.2e-05 22.9 0.0 6.6 7 0 0 7 7 6 4 Ankyrin repeat Ank_5 PF13857.6 KXG46131.1 - 1.8e-23 82.3 0.2 4.4e-07 30.0 0.0 5.5 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXG46131.1 - 3.7e-22 78.4 1.5 3.5e-08 33.8 0.0 5.4 3 1 2 6 6 5 4 Ankyrin repeats (many copies) NACHT PF05729.12 KXG46131.1 - 8.2e-06 25.8 0.0 2.3e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXG46131.1 - 5.2e-05 23.7 0.0 0.00013 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ANAPC4_WD40 PF12894.7 KXG46131.1 - 0.0023 18.2 0.8 5.7 7.3 0.1 4.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Helo_like_N PF17111.5 KXG46131.1 - 0.0042 16.5 0.2 0.015 14.7 0.1 2.0 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Nup160 PF11715.8 KXG46131.1 - 0.0043 15.8 0.7 1.4 7.4 0.2 3.6 3 1 1 4 4 4 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KXG46131.1 - 0.032 13.2 0.6 11 4.9 0.0 3.0 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain zf-C2H2_3rep PF18868.1 KXG46131.1 - 0.055 14.2 0.2 0.26 12.0 0.1 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Carbpep_Y_N PF05388.11 KXG46131.1 - 0.057 14.0 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide zf-H2C2_2 PF13465.6 KXG46131.1 - 2.9 8.5 9.6 3.3 8.3 0.1 3.3 3 0 0 3 3 2 0 Zinc-finger double domain Myb_DNA-binding PF00249.31 KXG46132.1 - 5.9e-06 26.4 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXG46132.1 - 0.0034 17.6 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KXG46132.1 - 0.17 12.2 2.8 1.5 9.2 0.5 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain UPF0016 PF01169.19 KXG46133.1 - 2e-40 136.9 25.4 3.4e-20 72.2 10.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Ion_trans PF00520.31 KXG46133.1 - 0.035 13.4 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Ion transport protein DUF3357 PF11837.8 KXG46133.1 - 2.9 8.4 5.4 9.3 6.8 0.4 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Xylo_C PF12529.8 KXG46134.1 - 8.3e-05 22.3 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Xylosyltransferase C terminal LAM_C PF12544.8 KXG46134.1 - 0.00024 21.3 0.1 0.0005 20.2 0.1 1.5 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.21 KXG46134.1 - 0.04 14.3 0.1 0.1 13.0 0.1 1.9 1 1 0 1 1 1 0 Radical SAM superfamily Dala_Dala_lig_C PF07478.13 KXG46135.1 - 7.1e-26 91.0 0.0 1.8e-25 89.7 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 KXG46135.1 - 0.00029 20.5 0.0 0.00075 19.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KXG46135.1 - 0.0078 16.3 0.0 0.11 12.5 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KXG46135.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TTL PF03133.15 KXG46135.1 - 0.012 14.7 0.0 2.1 7.4 0.0 2.1 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family UPF0180 PF03698.13 KXG46135.1 - 0.038 14.2 0.1 0.57 10.4 0.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0180) CPSase_L_D2 PF02786.17 KXG46135.1 - 0.077 12.5 0.0 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain MFS_1 PF07690.16 KXG46136.1 - 1.9e-51 175.1 65.4 3.4e-31 108.5 21.8 4.8 3 2 2 5 5 5 2 Major Facilitator Superfamily HATPase_c PF02518.26 KXG46136.1 - 3.5e-22 79.0 0.0 7.3e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXG46136.1 - 1.4e-20 73.6 0.7 3.3e-20 72.3 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KXG46136.1 - 7.2e-13 48.4 0.1 3.1e-12 46.3 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Sugar_tr PF00083.24 KXG46136.1 - 1.2e-12 47.5 8.9 1.2e-12 47.5 8.9 4.5 4 1 0 4 4 4 2 Sugar (and other) transporter OATP PF03137.20 KXG46136.1 - 0.06 11.6 15.7 0.03 12.6 3.4 3.4 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_7_1 PF16081.5 KXG46136.1 - 0.52 10.5 8.0 0.78 9.9 0.4 2.7 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Amidohydro_2 PF04909.14 KXG46137.1 - 3.9e-14 53.1 0.0 6.2e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Aldedh PF00171.22 KXG46138.1 - 1.9e-152 508.0 0.1 2.1e-152 507.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NAD_binding_4 PF07993.12 KXG46139.1 - 4.8e-38 130.8 0.0 7.5e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXG46139.1 - 8.5e-29 100.4 0.0 1.8e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KXG46139.1 - 1.2e-13 51.1 0.0 2.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXG46139.1 - 8e-05 21.8 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 KXG46139.1 - 0.00019 21.7 0.0 0.00042 20.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 KXG46139.1 - 0.00028 20.4 0.0 0.00079 18.9 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXG46139.1 - 0.011 15.4 0.1 0.042 13.4 0.0 2.1 3 0 0 3 3 3 0 NmrA-like family NAD_binding_10 PF13460.6 KXG46139.1 - 0.021 14.7 0.0 0.072 13.0 0.0 2.0 1 1 0 1 1 1 0 NAD(P)H-binding KR PF08659.10 KXG46139.1 - 0.045 13.7 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 KR domain UvrC_HhH_N PF08459.11 KXG46139.1 - 0.088 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal Glyco_hydro_18 PF00704.28 KXG46140.1 - 2.8e-80 270.4 0.4 3.4e-80 270.1 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KXG46140.1 - 2e-07 31.4 19.0 3.7e-07 30.5 19.0 1.5 1 0 0 1 1 1 1 Chitin recognition protein Trypan_PARP PF05887.11 KXG46140.1 - 0.00074 19.5 6.2 0.0019 18.2 6.2 1.6 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) CBP_BcsO PF17037.5 KXG46140.1 - 0.11 12.7 1.2 35 4.5 2.3 2.5 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsO Glyco_hydro_66 PF13199.6 KXG46140.1 - 0.12 10.9 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 GPI2 PF06432.11 KXG46141.1 - 1.5e-132 441.2 5.2 1.8e-132 441.0 5.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4191 PF13829.6 KXG46141.1 - 0.66 9.3 1.8 1.6 8.0 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) FA_desaturase PF00487.24 KXG46141.1 - 1.7 8.4 5.9 4.9 6.9 3.4 2.2 2 0 0 2 2 2 0 Fatty acid desaturase Fumble PF03630.14 KXG46144.1 - 7.9e-143 475.6 0.0 9.8e-143 475.3 0.0 1.1 1 0 0 1 1 1 1 Fumble DEAD PF00270.29 KXG46145.1 - 3e-45 154.1 0.0 5.4e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG46145.1 - 1.3e-25 89.9 0.0 7.8e-24 84.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG46145.1 - 0.0041 17.1 0.0 0.0076 16.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF5427 PF10310.9 KXG46145.1 - 2 7.3 8.9 2.9 6.8 8.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Polysacc_deac_1 PF01522.21 KXG46146.1 - 1.7e-17 63.5 0.0 6.7e-17 61.6 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXG46146.1 - 0.0086 15.7 0.1 0.017 14.8 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) PBP1_TM PF14812.6 KXG46146.1 - 0.049 14.0 10.3 0.093 13.1 10.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal eIF3_subunit PF08597.10 KXG46146.1 - 0.12 12.2 4.8 0.2 11.6 4.8 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit YL1 PF05764.13 KXG46146.1 - 0.29 11.2 2.1 0.44 10.6 2.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Fringe PF02434.16 KXG46147.1 - 6.2e-09 35.7 0.0 1.1e-07 31.5 0.0 2.3 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.6 KXG46147.1 - 0.07 13.0 1.2 0.14 12.0 1.2 1.5 1 0 0 1 1 1 0 PAN domain DUF496 PF04363.12 KXG46147.1 - 0.086 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF496) Glyco_transf_34 PF05637.12 KXG46147.1 - 0.12 12.0 0.8 0.36 10.5 0.3 1.8 2 0 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family DFP PF04127.15 KXG46148.1 - 1.3e-13 51.2 0.0 1.4e-05 25.0 0.0 3.2 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Abhydrolase_3 PF07859.13 KXG46150.1 - 1.8e-38 132.5 0.0 2.2e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXG46150.1 - 3.4e-06 26.7 0.0 2.7e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KXG46150.1 - 0.058 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 KXG46150.1 - 0.071 12.0 0.0 0.71 8.7 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase enzyme AXE1 PF05448.12 KXG46150.1 - 0.17 10.6 0.0 9.6 4.8 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) CENP-O PF09496.10 KXG46152.1 - 1e-64 218.4 0.0 1.5e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Acatn PF13000.7 KXG46153.1 - 1.6e-162 541.8 17.2 1.2e-80 271.7 8.5 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 MFS_1_like PF12832.7 KXG46153.1 - 0.0029 16.6 7.6 0.0029 16.6 7.6 1.5 2 0 0 2 2 2 1 MFS_1 like family Pkinase PF00069.25 KXG46156.1 - 3.8e-13 49.4 0.1 1.8e-12 47.2 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG46156.1 - 5.3e-12 45.6 0.0 1.4e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXG46156.1 - 0.0003 20.8 0.1 0.00046 20.2 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXG46156.1 - 0.0048 16.5 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KXG46156.1 - 0.01 15.2 0.5 0.019 14.3 0.5 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KXG46156.1 - 0.067 12.2 0.2 0.13 11.2 0.1 1.4 2 0 0 2 2 2 0 Seadornavirus VP7 Kinase-PolyVal PF18762.1 KXG46156.1 - 0.11 12.4 0.0 5.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Pkinase_fungal PF17667.1 KXG46156.1 - 0.86 8.3 2.1 1.9 7.2 1.4 1.6 1 1 1 2 2 2 0 Fungal protein kinase Yae1_N PF09811.9 KXG46157.1 - 2.7e-11 42.9 0.8 5.6e-11 41.9 0.2 1.9 1 1 1 2 2 2 1 Essential protein Yae1, N terminal VASP_tetra PF08776.11 KXG46159.1 - 0.16 11.5 4.3 0.27 10.8 4.3 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain Peptidase_S64 PF08192.11 KXG46159.1 - 0.99 7.8 6.5 1.8 7.0 6.5 1.4 1 0 0 1 1 1 0 Peptidase family S64 F-box PF00646.33 KXG46161.1 - 0.012 15.4 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 F-box domain IU_nuc_hydro PF01156.19 KXG46162.1 - 2.5e-44 152.1 0.0 3.1e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Retrotran_gag_2 PF14223.6 KXG46165.1 - 0.0037 16.9 0.0 0.0055 16.4 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type MFS_1 PF07690.16 KXG46169.1 - 1.4e-41 142.6 35.4 1.4e-41 142.6 35.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4112 PF13430.6 KXG46169.1 - 1.5 9.2 0.0 1.5 9.2 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4112) DLH PF01738.18 KXG46170.1 - 3.8e-27 95.3 0.0 5e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family SUR7 PF06687.12 KXG46171.1 - 5.8e-26 91.4 14.5 7.9e-26 91.0 14.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family SCIMP PF15050.6 KXG46171.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 SCIMP protein FTO_NTD PF12933.7 KXG46172.1 - 0.081 12.1 0.0 0.081 12.1 0.0 1.1 1 0 0 1 1 1 0 FTO catalytic domain DUF3433 PF11915.8 KXG46173.1 - 1e-35 122.0 19.2 6.7e-27 93.8 3.1 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) AWPM-19 PF05512.11 KXG46174.1 - 0.087 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 AWPM-19-like family G-patch PF01585.23 KXG46175.1 - 1.9e-12 46.9 0.5 4.4e-12 45.7 0.5 1.7 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KXG46175.1 - 6.6e-10 38.7 0.0 0.00023 20.9 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 KXG46175.1 - 2e-06 27.0 4.5 4.4e-06 25.9 4.5 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 KXG46175.1 - 1.2e-05 25.3 0.2 3.2e-05 23.9 0.2 1.7 1 0 0 1 1 1 1 G-patch domain RED_N PF07808.13 KXG46175.1 - 0.022 14.4 0.5 0.022 14.4 0.5 1.7 2 0 0 2 2 2 0 RED-like protein N-terminal region Alpha-amylase PF00128.24 KXG46176.1 - 9.5e-111 370.6 4.0 1.4e-110 370.0 4.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KXG46176.1 - 5.2e-07 29.7 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Cyc-maltodext_C PF10438.9 KXG46176.1 - 0.069 13.3 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain MoaE PF02391.17 KXG46177.1 - 4.8e-36 123.5 0.0 5.9e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 MoaE protein SCO1-SenC PF02630.14 KXG46178.1 - 1.8e-46 157.4 0.1 3e-46 156.6 0.1 1.4 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KXG46178.1 - 0.00019 21.3 0.0 0.0005 20.0 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KXG46178.1 - 0.003 17.9 0.0 0.0079 16.5 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KXG46178.1 - 0.034 13.8 0.0 0.09 12.5 0.0 1.7 1 1 0 1 1 1 0 Redoxin Pox_A12 PF04651.13 KXG46178.1 - 0.15 12.1 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein Phosphoesterase PF04185.14 KXG46179.1 - 1.4e-60 205.4 0.5 2.2e-60 204.7 0.5 1.3 1 0 0 1 1 1 1 Phosphoesterase family FAD_binding_3 PF01494.19 KXG46180.1 - 8.4e-81 271.9 0.0 1e-80 271.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG46180.1 - 7.1e-05 22.2 0.0 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG46180.1 - 9e-05 22.6 0.0 0.00031 20.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXG46180.1 - 0.00012 21.7 0.0 0.00072 19.2 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXG46180.1 - 0.00035 19.4 0.0 0.00069 18.4 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KXG46180.1 - 0.00044 19.5 0.0 0.00089 18.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KXG46180.1 - 0.001 18.2 0.4 0.0096 15.0 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KXG46180.1 - 0.0014 17.9 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family SE PF08491.10 KXG46180.1 - 0.0015 17.7 0.1 0.0053 15.8 0.1 1.8 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.27 KXG46180.1 - 0.0034 17.9 0.1 0.14 12.7 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG46180.1 - 0.021 14.8 0.2 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXG46180.1 - 0.028 13.7 0.1 0.049 12.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXG46180.1 - 0.084 13.1 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain XdhC_C PF13478.6 KXG46180.1 - 0.1 13.1 0.0 0.57 10.7 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain Fungal_trans PF04082.18 KXG46181.1 - 4.7e-19 68.4 0.2 8.2e-19 67.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4791 PF16039.5 KXG46181.1 - 0.054 13.0 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4791) SNARE PF05739.19 KXG46183.1 - 6.8e-13 48.4 0.1 1.9e-12 47.0 0.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 KXG46183.1 - 4.4e-08 32.1 0.1 4.4e-08 32.1 0.1 2.3 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain KxDL PF10241.9 KXG46183.1 - 0.00035 20.8 0.2 0.9 9.9 0.1 2.9 2 0 0 2 2 2 2 Uncharacterized conserved protein Syntaxin PF00804.25 KXG46183.1 - 0.0084 15.8 7.8 0.025 14.3 0.1 3.0 2 1 1 3 3 3 1 Syntaxin SPATA48 PF15073.6 KXG46183.1 - 0.024 14.9 0.3 0.056 13.7 0.3 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated protein 48 DUF4988 PF16378.5 KXG46183.1 - 0.081 12.6 3.1 16 5.1 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function DIOX_N PF14226.6 KXG46185.1 - 4.2e-30 104.9 0.1 6.9e-30 104.2 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG46185.1 - 4.4e-24 84.9 0.0 7.3e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pectinesterase PF01095.19 KXG46186.1 - 5.1e-23 81.2 0.1 5.9e-19 67.9 0.4 2.1 2 0 0 2 2 2 2 Pectinesterase E1-E2_ATPase PF00122.20 KXG46187.1 - 1e-36 126.2 8.2 3.3e-36 124.5 0.3 3.8 3 2 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KXG46187.1 - 3.4e-17 63.4 0.0 9.4e-17 62.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXG46187.1 - 9.1e-11 41.3 0.3 3.6e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXG46187.1 - 0.0054 16.5 0.1 0.0099 15.6 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXG46187.1 - 0.015 15.4 0.0 0.056 13.5 0.0 1.9 2 0 0 2 2 2 0 Cation transport ATPase (P-type) GNVR PF13807.6 KXG46187.1 - 0.066 13.1 0.0 0.26 11.2 0.0 2.1 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase Lactamase_B PF00753.27 KXG46188.1 - 3.9e-06 27.0 0.4 0.00065 19.8 0.1 2.4 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXG46188.1 - 0.00071 19.2 0.2 0.0026 17.3 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain ABC1 PF03109.16 KXG46189.1 - 3.1e-20 72.5 0.5 3.8e-19 69.0 0.1 2.8 3 0 0 3 3 3 1 ABC1 family APH PF01636.23 KXG46189.1 - 0.056 13.4 0.1 0.18 11.7 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family TFIIS_M PF07500.14 KXG46191.1 - 6.4e-28 97.5 0.4 1.3e-27 96.4 0.4 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KXG46191.1 - 2.3e-18 65.7 4.7 4.4e-18 64.8 4.7 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KXG46191.1 - 4.5e-10 39.4 0.3 4.5e-10 39.4 0.3 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.8 KXG46191.1 - 0.023 14.4 1.3 0.054 13.2 0.1 2.1 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain ABC_transp_aux PF09822.9 KXG46191.1 - 0.062 12.8 0.4 0.093 12.2 0.4 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system DEPP PF15343.6 KXG46191.1 - 0.57 10.2 5.0 0.081 13.0 0.8 1.7 2 0 0 2 2 2 0 Decidual protein induced by progesterone family LRR_6 PF13516.6 KXG46192.1 - 3.1e-11 42.4 2.7 0.98 9.6 0.0 7.2 8 0 0 8 8 7 2 Leucine Rich repeat LRR_8 PF13855.6 KXG46192.1 - 2.5e-05 23.9 2.4 0.024 14.4 0.1 4.3 3 2 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 KXG46192.1 - 3.8e-05 23.9 5.8 0.36 11.3 0.0 4.8 6 0 0 6 6 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXG46192.1 - 0.00046 20.3 1.6 14 6.7 0.0 5.4 6 0 0 6 6 5 0 Leucine Rich Repeat Radial_spoke PF04712.12 KXG46192.1 - 0.42 9.5 10.4 1.2 8.0 9.8 1.9 2 0 0 2 2 2 0 Radial spokehead-like protein Nop14 PF04147.12 KXG46192.1 - 0.75 7.9 21.5 1 7.5 21.5 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KXG46192.1 - 1 8.7 21.5 1.5 8.2 21.5 1.2 1 0 0 1 1 1 0 SDA1 RNA_pol_Rpc4 PF05132.14 KXG46192.1 - 1.1 9.7 3.3 2 8.8 3.3 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Paf1 PF03985.13 KXG46192.1 - 2.4 7.1 16.8 3.3 6.6 16.8 1.3 1 0 0 1 1 1 0 Paf1 DARPP-32 PF05395.12 KXG46192.1 - 2.6 8.2 13.6 4.8 7.4 13.6 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 NOA36 PF06524.12 KXG46192.1 - 2.7 7.2 13.4 4 6.7 13.4 1.3 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 KXG46192.1 - 3 7.1 17.6 4.6 6.5 17.6 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 KXG46192.1 - 3.4 5.8 16.4 5.2 5.2 16.4 1.3 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 KXG46192.1 - 4.8 6.9 11.7 7.7 6.3 11.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Drc1-Sld2 PF11719.8 KXG46192.1 - 9.3 5.7 13.5 14 5.1 13.5 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein COX17 PF05051.13 KXG46193.1 - 1.1e-21 76.9 7.2 1.3e-21 76.6 7.2 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KXG46193.1 - 0.018 15.0 3.0 0.19 11.8 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Alg6_Alg8 PF03155.15 KXG46194.1 - 1.8e-105 353.7 19.7 2.3e-94 317.1 16.6 3.1 1 1 1 2 2 2 2 ALG6, ALG8 glycosyltransferase family RRM_1 PF00076.22 KXG46195.1 - 5.4e-45 151.1 0.0 1.9e-21 75.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXG46195.1 - 5.3e-06 26.5 0.0 0.068 13.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Utp14 PF04615.13 KXG46195.1 - 0.13 10.8 54.5 0.17 10.4 54.5 1.3 1 0 0 1 1 1 0 Utp14 protein Plasmodium_Vir PF05795.11 KXG46196.1 - 0.03 13.7 0.2 0.03 13.7 0.2 2.1 1 1 0 2 2 2 0 Plasmodium vivax Vir protein ABC2_membrane_5 PF13346.6 KXG46196.1 - 0.11 12.0 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Herpes_pp38 PF04846.13 KXG46196.1 - 0.13 12.2 0.2 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein FMN_bind_2 PF04299.12 KXG46197.1 - 6.2e-57 192.0 0.1 7.3e-57 191.7 0.1 1.0 1 0 0 1 1 1 1 Putative FMN-binding domain Ring_hydroxyl_A PF00848.19 KXG46198.1 - 7.3e-19 68.6 2.4 3.1e-16 60.0 1.8 2.9 2 1 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KXG46198.1 - 7.2e-14 51.5 0.0 1.4e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Dioxygenase_C PF00775.21 KXG46199.1 - 7.3e-42 142.9 0.0 9.6e-42 142.5 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXG46199.1 - 1.8e-24 85.3 0.0 3.1e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KXG46199.1 - 0.026 14.8 0.0 0.1 12.9 0.0 2.0 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain SpaA PF17802.1 KXG46199.1 - 0.061 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Prealbumin-like fold domain NAD_binding_10 PF13460.6 KXG46201.1 - 0.0022 17.9 0.0 0.0029 17.5 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding GST_N PF02798.20 KXG46202.1 - 6.9e-11 42.3 0.0 1.5e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXG46202.1 - 5.4e-08 33.1 0.0 9.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXG46202.1 - 1.7e-07 31.3 0.1 2.6e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXG46202.1 - 7.2e-07 29.4 0.1 1.6e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXG46202.1 - 5.6e-06 26.3 0.3 5.6e-06 26.3 0.3 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXG46202.1 - 1.8e-05 24.8 0.1 3.2e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXG46202.1 - 0.071 13.7 0.0 0.26 11.9 0.0 1.8 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Rubi_NSP_C PF12601.8 KXG46203.1 - 0.086 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Rubivirus non-structural protein Dicty_CAR PF05462.11 KXG46203.1 - 0.64 9.1 7.4 3 6.9 7.4 1.9 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor Fungal_trans PF04082.18 KXG46204.1 - 3.5e-10 39.4 2.8 3.5e-10 39.4 2.8 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG46204.1 - 3.6e-09 36.6 10.7 6.6e-09 35.8 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIMCO_N PF16844.5 KXG46204.1 - 0.073 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor, N-terminal ADH_N PF08240.12 KXG46205.1 - 4.2e-07 29.8 0.1 1.1e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG46205.1 - 1.4e-05 25.0 0.0 3.5e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LysM PF01476.20 KXG46207.1 - 1.3e-07 31.5 0.0 3.1e-05 23.9 0.3 2.6 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KXG46207.1 - 4e-06 27.2 5.2 1.8e-05 25.1 5.2 2.1 1 0 0 1 1 1 1 Chitin recognition protein VCBS PF13517.6 KXG46209.1 - 4.5e-28 97.6 15.9 8.4e-15 55.1 3.8 3.9 1 1 3 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KXG46209.1 - 2.2e-14 53.2 10.0 9.8e-05 22.4 0.7 3.4 3 0 0 3 3 3 3 FG-GAP repeat TcdB_toxin_midN PF12256.8 KXG46209.1 - 2.3e-05 23.8 2.0 0.73 9.2 0.1 3.1 2 1 1 3 3 3 3 Insecticide toxin TcdB middle/N-terminal region SLT_2 PF13406.6 KXG46209.1 - 0.26 10.5 0.2 13 5.0 0.0 2.7 3 0 0 3 3 3 0 Transglycosylase SLT domain EF-hand_1 PF00036.32 KXG46209.1 - 4 7.2 5.5 30 4.5 0.1 2.9 3 0 0 3 3 3 0 EF hand EF-hand_5 PF13202.6 KXG46209.1 - 8.6 6.0 6.5 24 4.6 0.6 2.5 2 0 0 2 2 2 0 EF hand Glyco_hydro_72 PF03198.14 KXG46210.1 - 9.8e-135 448.8 3.7 1.2e-134 448.5 3.7 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KXG46210.1 - 1.2e-05 24.9 0.2 0.00013 21.5 0.2 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FA_hydroxylase PF04116.13 KXG46211.1 - 5e-22 78.7 12.6 5e-22 78.7 12.6 1.6 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily HPS6 PF15702.5 KXG46211.1 - 0.0012 17.0 0.0 0.0015 16.7 0.0 1.1 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 6 protein Tyrosinase PF00264.20 KXG46212.1 - 5.8e-51 173.9 0.0 7.8e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase TFIIA PF03153.13 KXG46213.1 - 1.7 8.6 25.7 2.2 8.2 25.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Utp14 PF04615.13 KXG46213.1 - 2.5 6.6 23.3 3.2 6.2 23.3 1.1 1 0 0 1 1 1 0 Utp14 protein UQ_con PF00179.26 KXG46214.1 - 7.6e-39 132.6 0.0 8.6e-39 132.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXG46214.1 - 0.004 17.4 0.0 0.0046 17.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KXG46214.1 - 0.01 15.6 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UFC1 PF08694.11 KXG46214.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 HhH-GPD PF00730.25 KXG46215.1 - 3.1e-20 72.6 0.0 8.6e-20 71.2 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KXG46215.1 - 2e-08 33.6 0.1 6.1e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif AAA_11 PF13086.6 KXG46216.1 - 1.5e-63 215.1 0.2 4.5e-63 213.5 0.2 1.9 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KXG46216.1 - 1.7e-55 187.8 0.0 2.7e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXG46216.1 - 2.6e-13 50.1 0.0 5.5e-12 45.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXG46216.1 - 1.7e-09 38.1 0.0 4.8e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXG46216.1 - 5.8e-08 32.8 0.0 0.042 13.6 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KXG46216.1 - 1.5e-06 27.7 0.2 2.7e-05 23.6 0.2 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KXG46216.1 - 3.7e-06 27.2 0.1 7.5e-05 23.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KXG46216.1 - 1.3e-05 25.3 0.0 8.4e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KXG46216.1 - 5.4e-05 23.1 0.0 0.031 14.2 0.0 2.4 2 0 0 2 2 2 1 Helicase PhoH PF02562.16 KXG46216.1 - 5.5e-05 22.7 0.0 0.061 12.8 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.21 KXG46216.1 - 0.00011 21.9 0.0 0.00028 20.5 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.14 KXG46216.1 - 0.00095 19.2 0.1 0.0049 16.8 0.1 2.1 2 0 0 2 2 2 1 Flavivirus DEAD domain DEAD PF00270.29 KXG46216.1 - 0.0012 18.7 0.2 0.038 13.7 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_24 PF13479.6 KXG46216.1 - 0.0016 18.2 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXG46216.1 - 0.0031 17.5 0.1 0.073 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) PIF1 PF05970.14 KXG46216.1 - 0.0044 16.2 0.0 1.3 8.1 0.0 2.5 2 0 0 2 2 2 1 PIF1-like helicase AAA_16 PF13191.6 KXG46216.1 - 0.0056 17.1 0.0 0.012 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.6 KXG46216.1 - 0.0062 16.3 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain T2SSE PF00437.20 KXG46216.1 - 0.0086 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 KXG46216.1 - 0.025 13.5 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 KXG46216.1 - 0.029 14.8 0.0 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KXG46216.1 - 0.037 13.7 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein HEM4 PF02602.15 KXG46216.1 - 0.062 12.6 0.2 0.53 9.6 0.0 2.1 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD AAA_33 PF13671.6 KXG46216.1 - 0.099 12.8 0.0 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain UvrD_C PF13361.6 KXG46216.1 - 0.099 12.0 0.0 4.9 6.4 0.0 2.6 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain SRP54 PF00448.22 KXG46216.1 - 0.12 12.0 0.0 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CbiA PF01656.23 KXG46216.1 - 0.14 12.2 0.1 0.36 10.9 0.1 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SKI PF01202.22 KXG46216.1 - 0.15 12.2 1.3 1.4 9.0 0.1 2.6 2 1 0 3 3 2 0 Shikimate kinase TK PF00265.18 KXG46216.1 - 0.21 11.4 0.0 3.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Thymidine kinase Syntaxin-6_N PF09177.11 KXG46217.1 - 0.022 15.3 0.3 2 9.0 0.0 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal FAD_binding_3 PF01494.19 KXG46218.1 - 2.4e-11 43.5 0.3 4.2e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXG46218.1 - 3.1e-05 24.1 0.1 8.9e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXG46218.1 - 0.0018 17.9 0.3 0.0057 16.3 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXG46218.1 - 0.036 14.0 0.2 0.093 12.7 0.1 2.0 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXG46218.1 - 0.039 14.5 0.0 0.15 12.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG46218.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXG46218.1 - 0.13 11.1 0.2 0.24 10.2 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase adh_short PF00106.25 KXG46219.1 - 3.9e-29 101.5 0.1 1e-28 100.1 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase MFS_1 PF07690.16 KXG46219.1 - 1.4e-25 90.0 44.9 2.3e-25 89.3 44.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily adh_short_C2 PF13561.6 KXG46219.1 - 6.3e-25 88.1 0.0 1.2e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Acetyltransf_1 PF00583.25 KXG46219.1 - 0.0015 18.8 0.0 0.0041 17.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Epimerase PF01370.21 KXG46219.1 - 0.0062 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXG46219.1 - 0.013 15.4 0.0 0.048 13.6 0.0 1.9 1 1 0 1 1 1 0 KR domain Acetyltransf_10 PF13673.7 KXG46219.1 - 0.038 13.9 0.0 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXG46219.1 - 0.06 13.8 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3712 PF12505.8 KXG46220.1 - 1.8e-34 118.7 0.4 1.8e-34 118.7 0.4 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) DUF4597 PF15366.6 KXG46220.1 - 0.038 13.7 0.1 0.41 10.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Sel1 PF08238.12 KXG46221.1 - 7e-12 45.6 6.1 0.0011 19.6 0.0 3.9 4 0 0 4 4 4 3 Sel1 repeat Far-17a_AIG1 PF04750.14 KXG46222.1 - 0.0017 17.7 20.0 0.0036 16.6 20.0 1.6 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein DUF1776 PF08643.10 KXG46223.1 - 1.6e-103 346.1 0.0 2e-103 345.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KXG46223.1 - 9.3e-07 28.5 0.0 3.9e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG46223.1 - 0.0044 16.6 0.0 0.092 12.3 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase WLM PF08325.10 KXG46224.1 - 3.1e-64 216.6 0.2 4.6e-64 216.0 0.2 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KXG46224.1 - 0.00014 21.1 4.1 0.00014 21.1 4.1 3.3 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 KXG46224.1 - 0.021 14.9 1.3 0.059 13.4 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF45 SprT-like PF10263.9 KXG46224.1 - 0.1 12.5 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 SprT-like family DUF4379 PF14311.6 KXG46224.1 - 0.11 12.9 7.1 2.8 8.4 0.0 2.8 2 0 0 2 2 2 0 Probable Zinc-ribbon domain DZR PF12773.7 KXG46224.1 - 2 8.5 12.6 20 5.3 12.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon WD40 PF00400.32 KXG46225.1 - 1.6e-50 168.0 31.2 3.3e-06 27.7 0.1 12.2 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.12 KXG46225.1 - 1.2e-20 73.9 0.2 2.4e-20 72.8 0.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KXG46225.1 - 7.9e-20 71.0 4.2 0.016 15.5 0.0 9.6 7 3 3 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXG46225.1 - 4.2e-07 29.0 0.7 0.33 9.5 0.0 5.5 5 1 1 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXG46225.1 - 1.1e-06 27.9 0.3 1.2 8.0 0.0 4.9 3 2 2 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KXG46225.1 - 0.0034 15.8 0.0 0.1 10.9 0.0 2.5 2 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KXG46225.1 - 0.0079 15.6 0.0 3.6 6.8 0.0 3.4 3 0 0 3 3 3 1 WD40-like domain PALB2_WD40 PF16756.5 KXG46225.1 - 0.068 12.1 1.3 6.6 5.5 0.2 3.3 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain P34-Arc PF04045.14 KXG46226.1 - 7.6e-108 359.7 0.1 9.3e-108 359.5 0.1 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc SpoIIE PF07228.12 KXG46228.1 - 0.0036 17.2 0.0 0.025 14.5 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KXG46228.1 - 0.0044 16.7 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C Fcf1 PF04900.12 KXG46229.1 - 1.2e-19 70.5 0.2 3.1e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 Fcf1 Tmemb_9 PF05434.11 KXG46229.1 - 0.044 13.7 0.4 1.9 8.4 0.0 2.6 2 0 0 2 2 2 0 TMEM9 Cmc1 PF08583.10 KXG46230.1 - 1.6e-17 63.3 3.7 2.1e-17 62.9 3.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 KXG46230.1 - 0.01 16.1 0.8 3.4 8.0 0.1 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 GCK PF07802.11 KXG46230.1 - 0.17 12.3 1.5 0.29 11.6 1.1 1.5 1 1 0 1 1 1 0 GCK domain UPF0203 PF05254.12 KXG46230.1 - 0.17 12.2 1.6 5.6 7.3 0.7 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) DUF3128 PF11326.8 KXG46230.1 - 1 9.8 4.5 4.3 7.8 4.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) WD40 PF00400.32 KXG46231.1 - 2.9e-17 62.7 7.8 0.002 18.9 0.3 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG46231.1 - 1.5e-07 31.6 0.6 0.01 16.1 0.3 4.7 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXG46231.1 - 1.9e-07 30.1 0.9 0.00016 20.4 0.4 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXG46231.1 - 0.044 12.5 0.0 2.3 6.9 0.0 2.5 2 1 1 3 3 3 0 Nup133 N terminal like Aldo_ket_red PF00248.21 KXG46232.1 - 3e-47 161.2 0.0 2.8e-45 154.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Sof1 PF04158.14 KXG46232.1 - 0.029 14.6 0.0 0.3 11.4 0.0 2.4 2 0 0 2 2 2 0 Sof1-like domain FMO-like PF00743.19 KXG46233.1 - 1e-23 83.6 0.0 3.7e-16 58.6 0.1 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXG46233.1 - 1.3e-22 80.4 0.0 2.6e-20 72.9 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG46233.1 - 5.7e-15 55.3 0.0 2.3e-12 46.8 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG46233.1 - 1.8e-08 34.8 1.3 0.01 16.4 0.1 3.9 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG46233.1 - 4.7e-08 32.6 0.1 2.1e-06 27.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KXG46233.1 - 1.1e-07 31.4 0.5 0.009 15.3 0.3 3.2 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 KXG46233.1 - 1.4e-06 28.4 0.0 0.0021 18.2 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXG46233.1 - 8.8e-06 25.3 0.1 0.21 10.9 0.0 3.5 4 0 0 4 4 4 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KXG46233.1 - 1.7e-05 24.3 0.0 0.081 12.3 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KXG46233.1 - 0.00014 21.6 1.7 0.051 13.2 0.2 3.6 2 2 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXG46233.1 - 0.00028 20.2 0.0 0.78 8.9 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KXG46233.1 - 0.00043 19.5 0.4 0.14 11.2 0.0 2.6 3 0 0 3 3 3 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXG46233.1 - 0.0014 17.8 0.0 0.023 13.8 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXG46233.1 - 0.0017 18.4 2.1 7.7 6.5 0.2 3.6 3 1 1 4 4 4 2 FAD-NAD(P)-binding HI0933_like PF03486.14 KXG46233.1 - 0.0063 15.3 0.4 1.4 7.5 0.3 3.0 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 KXG46233.1 - 0.16 11.0 0.4 2.5 7.1 0.5 2.4 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 KXG46233.1 - 0.19 11.0 0.0 9.7 5.4 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 KXG46234.1 - 3.4e-18 66.6 0.0 1.8e-16 61.1 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXG46234.1 - 1.2e-06 28.5 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KXG46234.1 - 0.11 13.2 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KXG46235.1 - 8.5e-113 377.6 22.7 1e-112 377.3 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG46235.1 - 9.8e-25 87.2 58.1 8.5e-19 67.7 29.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG46235.1 - 1e-06 27.5 11.2 8.5e-05 21.2 4.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Fungal_trans_2 PF11951.8 KXG46236.1 - 0.0027 16.6 0.3 0.013 14.3 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Beta-lactamase PF00144.24 KXG46237.1 - 8.1e-38 130.5 0.2 1.1e-37 130.1 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase DIE2_ALG10 PF04922.12 KXG46238.1 - 2.1e-126 422.4 0.1 3.1e-126 421.8 0.1 1.3 1 0 0 1 1 1 1 DIE2/ALG10 family Sld5 PF05916.11 KXG46239.1 - 3.3e-34 117.6 0.0 6.6e-34 116.7 0.0 1.5 1 1 0 1 1 1 1 GINS complex protein CUE PF02845.16 KXG46240.1 - 2.6e-10 39.8 0.0 4.8e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 KXG46240.1 - 0.01 15.4 10.7 0.017 14.7 10.7 1.3 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) HTH_32 PF13565.6 KXG46240.1 - 0.013 16.1 0.3 1.6 9.4 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain tRNA_anti-like PF12869.7 KXG46240.1 - 0.13 11.9 0.1 0.56 9.8 0.3 1.8 2 0 0 2 2 2 0 tRNA_anti-like SMC_N PF02463.19 KXG46241.1 - 3.8e-67 225.9 13.8 6.1e-66 222.0 13.8 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXG46241.1 - 5.2e-20 71.9 6.2 1.1e-19 70.8 0.4 3.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXG46241.1 - 1.7e-09 38.0 8.1 0.0002 21.3 0.2 3.7 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXG46241.1 - 0.00014 21.5 0.1 0.00034 20.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain HIP1_clath_bdg PF16515.5 KXG46241.1 - 0.00036 21.1 12.0 0.00036 21.1 12.0 9.6 2 2 6 10 10 10 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Methyltransf_25 PF13649.6 KXG46242.1 - 3e-12 47.1 0.0 6.9e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG46242.1 - 2.1e-11 44.3 0.0 7.2e-11 42.6 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG46242.1 - 1.6e-09 37.7 0.0 2.3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG46242.1 - 6e-08 32.3 0.0 1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXG46242.1 - 8.7e-07 28.9 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG46242.1 - 1.1e-06 29.3 0.0 1.8e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NOT2_3_5 PF04153.18 KXG46243.1 - 2.8e-27 95.4 0.0 5.8e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family MRP-L47 PF06984.13 KXG46244.1 - 2.2e-22 79.0 0.0 3.2e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 KXG46244.1 - 0.016 15.2 0.9 0.055 13.4 0.9 1.8 1 1 0 1 1 1 0 Ribosomal L29 protein Clc-like PF07062.12 KXG46244.1 - 0.098 12.1 0.8 0.15 11.5 0.8 1.2 1 0 0 1 1 1 0 Clc-like GDI PF00996.18 KXG46245.1 - 4.5e-191 635.1 0.1 5.3e-191 634.8 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KXG46245.1 - 0.027 14.7 0.0 0.085 13.1 0.0 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXG46245.1 - 0.13 12.8 0.2 0.68 10.5 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 4HBT PF03061.22 KXG46246.1 - 9.5e-13 48.3 0.0 1.5e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KXG46246.1 - 3.1e-05 24.3 0.0 4.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily ORC4_C PF14629.6 KXG46247.1 - 3.1e-49 167.3 0.0 4.8e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KXG46247.1 - 2.9e-15 57.0 1.7 3.1e-15 57.0 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA PF00004.29 KXG46247.1 - 1.6e-08 35.1 0.0 5.9e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXG46247.1 - 6.4e-07 29.4 0.0 2.2e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 KXG46247.1 - 1.2e-05 24.8 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.6 KXG46247.1 - 1.8e-05 25.0 0.1 6.3e-05 23.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain ATPase_2 PF01637.18 KXG46247.1 - 6.8e-05 22.9 0.0 0.00029 20.9 0.0 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 KXG46247.1 - 0.00024 20.3 0.0 0.0004 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KXG46247.1 - 0.0017 18.7 0.0 0.0036 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.25 KXG46247.1 - 0.0049 16.6 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 KXG46247.1 - 0.0056 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 KXG46247.1 - 0.0095 16.0 0.0 0.063 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KXG46247.1 - 0.022 15.3 0.0 0.066 13.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 KXG46247.1 - 0.022 13.9 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PIF1 PF05970.14 KXG46247.1 - 0.068 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_5 PF07728.14 KXG46247.1 - 0.13 12.3 0.1 0.46 10.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KXG46247.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 KXG46247.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 KXG46247.1 - 0.16 11.3 0.0 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein DNA_pol_phi PF04931.13 KXG46247.1 - 0.38 8.8 6.8 0.69 7.9 6.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KXG46247.1 - 0.49 8.6 18.0 0.78 7.9 18.0 1.3 1 0 0 1 1 1 0 Nop14-like family RGS PF00615.19 KXG46248.1 - 7.3e-35 119.8 0.1 1.7e-34 118.6 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KXG46248.1 - 7.8e-26 89.9 0.1 8.6e-20 70.6 0.0 3.5 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CDC73_C PF05179.14 KXG46249.1 - 2e-56 190.0 0.0 3.5e-56 189.2 0.0 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal MFS_1 PF07690.16 KXG46249.1 - 6.6e-15 54.9 85.4 7.6e-12 44.8 41.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily SET PF00856.28 KXG46250.1 - 4e-08 33.8 0.1 1e-07 32.5 0.0 1.8 2 0 0 2 2 2 1 SET domain PHD PF00628.29 KXG46250.1 - 7.8e-06 25.7 9.2 1.5e-05 24.8 9.2 1.5 1 0 0 1 1 1 1 PHD-finger DUF2153 PF09921.9 KXG46250.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) AA_permease PF00324.21 KXG46251.1 - 1.9e-47 162.0 34.0 1.4e-46 159.1 34.0 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG46251.1 - 2.9e-08 33.0 38.4 3.2e-07 29.6 38.4 2.2 1 1 0 1 1 1 1 Amino acid permease YqhR PF11085.8 KXG46251.1 - 0.8 9.6 4.1 1.5 8.8 1.3 2.4 2 0 0 2 2 2 0 Conserved membrane protein YqhR WD40 PF00400.32 KXG46252.1 - 4e-07 30.6 9.4 0.047 14.6 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG46252.1 - 0.0035 17.6 0.0 0.57 10.5 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXG46252.1 - 0.013 14.2 1.2 0.78 8.3 0.2 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Rav1p_C PF12234.8 KXG46252.1 - 0.12 10.7 0.0 0.22 9.9 0.0 1.3 1 0 0 1 1 1 0 RAVE protein 1 C terminal Glycos_transf_4 PF00953.21 KXG46253.1 - 5e-32 111.1 10.5 5e-32 111.1 10.5 2.4 3 1 0 3 3 3 1 Glycosyl transferase family 4 SecE PF00584.20 KXG46253.1 - 1.3 9.0 0.0 1.3 9.0 0.0 4.7 5 0 0 5 5 5 0 SecE/Sec61-gamma subunits of protein translocation complex UNC-93 PF05978.16 KXG46254.1 - 6.3e-08 32.5 3.5 6.3e-08 32.5 3.5 2.4 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KXG46254.1 - 2.9e-05 23.2 42.7 0.00019 20.5 42.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_3_1 PF05106.12 KXG46254.1 - 5.2 7.6 7.7 1.8 9.1 0.9 3.0 2 1 1 3 3 3 0 Phage holin family (Lysis protein S) ADH_zinc_N PF00107.26 KXG46255.1 - 5e-13 49.2 0.1 1e-12 48.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG46255.1 - 0.00032 21.7 0.0 0.00063 20.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG46255.1 - 0.0018 18.1 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Aconitase PF00330.20 KXG46256.1 - 9.6e-161 535.8 0.0 1.2e-160 535.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXG46256.1 - 6.2e-40 136.6 0.0 1.2e-39 135.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain AA_permease_2 PF13520.6 KXG46257.1 - 1.8e-63 214.8 38.6 2.3e-63 214.5 38.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG46257.1 - 1.1e-18 67.1 35.3 1.5e-18 66.7 35.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF5480 PF17576.2 KXG46257.1 - 0.081 12.9 1.7 0.39 10.7 1.6 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5480) Alpha-amylase PF00128.24 KXG46258.1 - 2.9e-16 60.0 1.9 2.9e-16 60.0 1.9 2.7 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KXG46258.1 - 5.3e-14 52.5 0.1 8.9e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KXG46258.1 - 7.2e-05 22.4 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXG46258.1 - 0.048 13.7 0.3 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Pribosyltran PF00156.27 KXG46259.1 - 4.5e-14 52.3 0.3 6.5e-14 51.7 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MTHFR PF02219.17 KXG46260.1 - 3.7e-115 384.2 0.0 6e-115 383.5 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase HNH_2 PF13391.6 KXG46262.1 - 6.7e-15 55.0 0.5 1.1e-14 54.2 0.5 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF2418 PF10332.9 KXG46263.1 - 6.4e-38 129.2 0.4 2e-37 127.6 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) DUF393 PF04134.12 KXG46263.1 - 0.17 13.2 0.0 0.36 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF393 ATP-synt_F PF01990.17 KXG46264.1 - 1.9e-33 114.6 0.0 2.2e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.13 KXG46264.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 E1_DerP2_DerF2 PF02221.15 KXG46265.1 - 7.7e-27 94.4 0.1 1.1e-26 93.8 0.1 1.2 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 KXG46265.1 - 0.00036 20.9 0.0 0.00069 20.0 0.0 1.4 1 1 0 1 1 1 1 ML-like domain DUF1091 PF06477.13 KXG46265.1 - 0.077 13.5 0.1 0.44 11.1 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1091) AMP-binding PF00501.28 KXG46266.1 - 5e-58 196.7 0.0 6.8e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG46266.1 - 0.0041 18.1 0.0 0.009 17.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 KXG46267.1 - 1.3e-65 221.3 1.9 2.3e-65 220.6 1.9 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXG46267.1 - 5.1e-42 142.4 0.2 1.1e-41 141.3 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXG46267.1 - 0.0014 18.2 1.9 0.0043 16.7 1.3 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXG46267.1 - 0.011 15.6 1.2 0.57 10.1 0.1 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SasG_E PF17041.5 KXG46267.1 - 0.11 12.6 0.7 0.32 11.0 0.7 1.8 1 0 0 1 1 1 0 E domain DAP_B PF07930.12 KXG46268.1 - 3.3e-65 219.5 0.0 5.1e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 D-aminopeptidase, domain B Beta-lactamase PF00144.24 KXG46268.1 - 2.5e-43 148.6 0.0 4.5e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_17 PF00332.18 KXG46269.1 - 0.00011 21.9 1.2 0.00039 20.1 1.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 ATG22 PF11700.8 KXG46270.1 - 3.7e-134 447.9 29.5 4.4e-134 447.7 29.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KXG46270.1 - 5.5e-10 38.7 36.6 2.5e-05 23.4 13.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily VbhA PF18495.1 KXG46270.1 - 0.032 14.1 0.1 0.061 13.2 0.1 1.3 1 0 0 1 1 1 0 Antitoxin VbhA KH_8 PF17903.1 KXG46271.1 - 2.3e-32 110.9 0.0 6.8e-32 109.4 0.0 1.9 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KXG46271.1 - 0.011 15.6 0.0 0.036 13.9 0.0 2.0 1 1 0 1 1 1 0 KH domain Methyltransf_23 PF13489.6 KXG46272.1 - 1.9e-13 50.6 0.0 3.2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG46272.1 - 1.2e-11 45.1 0.0 4.3e-11 43.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG46272.1 - 8.5e-11 42.4 0.0 2.1e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG46272.1 - 1.6e-06 28.8 0.0 5.1e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG46272.1 - 4.7e-06 26.5 0.0 4.7e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXG46272.1 - 0.00018 20.9 0.0 0.017 14.4 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KXG46272.1 - 0.0022 17.5 0.0 0.016 14.6 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 KXG46272.1 - 0.0029 17.0 0.0 0.023 14.0 0.0 2.3 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KXG46272.1 - 0.057 13.5 0.0 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_29 PF03141.16 KXG46272.1 - 0.094 11.2 0.0 0.32 9.5 0.0 1.9 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Sen15 PF09631.10 KXG46272.1 - 0.15 12.4 0.0 2.2 8.7 0.0 2.4 2 1 0 2 2 2 0 Sen15 protein GCP_N_terminal PF17681.1 KXG46274.1 - 2.4e-65 221.2 0.0 4.1e-65 220.4 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXG46274.1 - 3.3e-59 200.9 4.1 3.3e-59 200.9 4.1 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal CLZ PF16526.5 KXG46274.1 - 0.02 15.3 0.7 0.02 15.3 0.7 2.9 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Proteasome PF00227.26 KXG46275.1 - 8.7e-58 194.9 0.1 1.1e-57 194.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXG46275.1 - 1.5e-12 47.0 0.2 3.6e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Methyltransf_8 PF05148.15 KXG46276.1 - 2.9e-55 187.5 0.0 1.3e-52 178.8 0.0 2.8 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KXG46276.1 - 8.5e-06 26.3 0.7 5e-05 23.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG46276.1 - 0.00038 21.1 0.0 0.016 15.9 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXG46276.1 - 0.94 9.5 0.0 0.94 9.5 0.0 2.9 2 1 0 2 2 2 0 Methyltransferase domain Mucin PF01456.17 KXG46276.1 - 5.8 6.9 14.6 11 6.0 14.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Zn_clus PF00172.18 KXG46277.1 - 2.2e-07 30.9 9.5 3.3e-07 30.3 9.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3557 PF12078.8 KXG46277.1 - 0.22 11.4 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) Ecl1 PF12855.7 KXG46277.1 - 2.2 9.4 14.0 3.3 8.9 14.0 1.3 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Fungal_trans_2 PF11951.8 KXG46278.1 - 1.4e-19 70.2 0.1 4.7e-14 52.0 0.2 3.1 3 0 0 3 3 3 3 Fungal specific transcription factor domain BAR_2 PF10455.9 KXG46280.1 - 2.5e-62 210.6 1.6 3.6e-62 210.1 1.6 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KXG46280.1 - 5.8e-21 75.2 7.8 1e-19 71.2 7.8 2.0 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KXG46280.1 - 0.0093 15.7 4.6 0.016 14.9 0.2 2.3 2 1 0 2 2 2 1 BAR domain of APPL family DUF4111 PF13427.6 KXG46280.1 - 0.012 15.8 0.1 0.061 13.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) SPATA19 PF15212.6 KXG46280.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 19, mitochondrial Arv1 PF04161.13 KXG46281.1 - 9.7e-56 189.2 0.2 7.4e-47 160.2 0.0 2.4 2 1 1 3 3 3 2 Arv1-like family CALCOCO1 PF07888.11 KXG46282.1 - 0.0012 17.8 20.7 0.0012 17.8 20.7 1.9 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like Csm1_N PF18504.1 KXG46282.1 - 0.012 15.9 4.4 0.012 15.9 4.4 4.1 4 0 0 4 4 4 0 Csm1 N-terminal domain CENP-F_leu_zip PF10473.9 KXG46282.1 - 0.013 15.5 20.4 0.013 15.5 20.4 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FPP PF05911.11 KXG46282.1 - 0.08 11.1 29.8 1 7.5 0.2 2.2 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil CREPT PF16566.5 KXG46282.1 - 0.37 10.9 29.7 0.18 12.0 9.8 3.3 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4201 PF13870.6 KXG46282.1 - 1.3 8.7 38.7 0.54 10.0 9.0 4.0 2 1 2 4 4 4 0 Domain of unknown function (DUF4201) Seryl_tRNA_N PF02403.22 KXG46282.1 - 9 6.6 25.8 0.72 10.1 15.0 2.8 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fungal_trans PF04082.18 KXG46283.1 - 4e-29 101.5 2.6 6.9e-29 100.7 2.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG46283.1 - 1.9e-06 27.9 4.3 4e-06 26.8 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF632 PF04782.12 KXG46283.1 - 0.18 11.1 0.4 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF632) Pox_A_type_inc PF04508.12 KXG46283.1 - 1.1 9.2 4.0 0.45 10.4 1.0 1.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat MFS_1 PF07690.16 KXG46284.1 - 4.8e-31 108.0 30.4 5.9e-31 107.7 30.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG46284.1 - 1.4e-06 27.5 15.1 2.1e-06 26.9 15.1 1.3 1 0 0 1 1 1 1 MFS_1 like family DLH PF01738.18 KXG46285.1 - 1e-21 77.5 0.0 1.2e-21 77.3 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KXG46285.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family adh_short_C2 PF13561.6 KXG46286.1 - 3.1e-54 184.0 0.2 5.1e-54 183.3 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG46286.1 - 3e-41 141.0 0.8 4.1e-41 140.6 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KXG46286.1 - 0.018 14.5 0.1 0.1 12.1 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXG46286.1 - 0.041 13.8 0.4 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CMD PF02627.20 KXG46287.1 - 2.6e-07 30.6 0.0 6.4e-05 22.9 0.0 2.4 2 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family GerA PF03323.13 KXG46287.1 - 0.085 11.3 0.1 0.1 11.1 0.1 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein PPP1R35_C PF15503.6 KXG46287.1 - 0.12 12.1 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus MmgE_PrpD PF03972.14 KXG46288.1 - 2.3e-115 385.6 2.3 2.8e-115 385.3 2.3 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Tht1 PF04163.12 KXG46288.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein LupA PF18242.1 KXG46288.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain Lactonase PF10282.9 KXG46289.1 - 5.9e-23 81.7 0.4 8e-23 81.2 0.4 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Acetyltransf_10 PF13673.7 KXG46290.1 - 4.1e-09 36.4 0.0 8.6e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG46290.1 - 2.3e-07 31.1 0.0 3.7e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXG46290.1 - 5.5e-07 29.9 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXG46290.1 - 0.022 14.8 0.1 0.044 13.9 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG46290.1 - 0.033 14.2 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein DJ-1_PfpI PF01965.24 KXG46291.1 - 1.2e-07 31.7 0.0 4.8e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KXG46291.1 - 0.041 13.6 0.0 0.26 11.0 0.0 2.0 1 1 0 1 1 1 0 ThiJ/PfpI family-like Fungal_trans PF04082.18 KXG46292.1 - 2.8e-25 88.9 0.2 4.7e-25 88.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG46292.1 - 2.2e-06 27.7 12.0 3.6e-06 27.0 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCD48 PF15799.5 KXG46292.1 - 0.026 12.9 0.3 0.037 12.3 0.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 End3 PF12761.7 KXG46292.1 - 0.11 12.7 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Pec_lyase_C PF00544.19 KXG46294.1 - 3.8e-14 52.8 6.8 4.1e-13 49.4 6.8 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXG46294.1 - 0.0061 16.4 13.2 0.53 10.1 6.3 2.3 1 1 1 2 2 2 2 Right handed beta helix region COesterase PF00135.28 KXG46295.1 - 9.5e-76 255.7 0.0 1.3e-75 255.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG46295.1 - 8.9e-06 25.7 0.4 3e-05 24.0 0.4 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXG46295.1 - 0.038 13.5 0.1 0.068 12.6 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family TSGP1 PF07771.11 KXG46295.1 - 0.061 13.5 2.7 0.12 12.5 2.7 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 YjcB PF15940.5 KXG46296.1 - 0.14 12.3 2.1 2.3 8.5 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function HNOBA PF07701.14 KXG46297.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Heme NO binding associated Flavoprotein PF02441.19 KXG46298.1 - 2.4e-46 157.4 0.0 4.6e-46 156.4 0.0 1.4 1 1 0 1 1 1 1 Flavoprotein adh_short PF00106.25 KXG46299.1 - 2.4e-37 128.3 0.0 3.9e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG46299.1 - 7.4e-23 81.3 0.0 9.9e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG46299.1 - 0.00033 20.6 0.0 0.00071 19.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXG46299.1 - 0.019 14.1 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Erg28 PF03694.13 KXG46300.1 - 1e-35 122.4 0.2 1.3e-35 122.1 0.2 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.22 KXG46301.1 - 3.3e-70 236.3 0.3 1.3e-68 231.1 0.2 2.3 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KXG46301.1 - 5.8e-58 195.3 0.3 1.2e-57 194.2 0.1 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 KXG46301.1 - 0.0021 16.9 0.2 0.23 10.3 0.0 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF4921) F-box-like PF12937.7 KXG46302.1 - 1.3e-05 25.0 0.5 3e-05 23.8 0.5 1.7 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 KXG46303.1 - 3.5e-42 144.6 51.1 1.7e-41 142.4 47.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG46303.1 - 1.2e-05 24.4 25.7 0.0001 21.3 25.7 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Sm_multidrug_ex PF06695.11 KXG46303.1 - 0.79 10.4 8.8 29 5.3 4.8 3.3 3 0 0 3 3 3 0 Putative small multi-drug export protein DSBA PF01323.20 KXG46304.1 - 4.4e-23 82.1 0.0 4.9e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain NAD_binding_2 PF03446.15 KXG46305.1 - 2.4e-27 96.0 0.0 3.7e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXG46305.1 - 1.6e-08 34.9 0.1 4.7e-08 33.3 0.1 1.8 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KXG46305.1 - 1.4e-06 28.8 0.0 2.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KXG46305.1 - 1.8e-06 28.1 0.0 3.7e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KXG46305.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KXG46305.1 - 0.024 14.2 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 KXG46305.1 - 0.081 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AdoHcyase_NAD PF00670.21 KXG46305.1 - 0.88 9.6 6.1 0.33 11.0 0.2 2.9 3 1 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sugar_tr PF00083.24 KXG46306.1 - 4.3e-137 457.7 29.0 4.9e-137 457.5 29.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG46306.1 - 2.2e-24 86.1 31.2 3.4e-23 82.2 26.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KXG46306.1 - 0.014 15.6 2.3 0.014 15.6 2.3 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) DUF4293 PF14126.6 KXG46306.1 - 0.053 13.8 0.3 0.053 13.8 0.3 3.1 2 1 1 4 4 4 0 Domain of unknown function (DUF4293) NOG1_N PF17835.1 KXG46307.1 - 1.4e-48 164.9 1.3 1.7e-48 164.6 0.1 1.8 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KXG46307.1 - 7.7e-28 96.3 3.7 1.9e-27 95.0 3.7 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KXG46307.1 - 9.3e-26 89.4 0.2 1.9e-25 88.4 0.2 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KXG46307.1 - 7.6e-16 58.2 0.0 1.9e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXG46307.1 - 1.4e-07 31.2 0.0 4.4e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXG46307.1 - 0.0019 18.1 0.1 0.55 10.1 0.1 2.8 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KXG46307.1 - 0.0066 16.5 0.0 4 7.5 0.0 2.6 1 1 0 2 2 2 2 Dynamin family Gtr1_RagA PF04670.12 KXG46307.1 - 0.04 13.3 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Sigma54_activ_2 PF14532.6 KXG46307.1 - 0.043 13.9 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 KXG46307.1 - 0.052 13.9 1.3 0.32 11.4 0.0 2.9 4 0 0 4 4 4 0 AAA ATPase domain Acetyltransf_1 PF00583.25 KXG46308.1 - 2.5e-15 56.7 0.0 4.4e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXG46308.1 - 1.2e-13 51.1 0.0 1.7e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXG46308.1 - 1.2e-10 41.6 0.0 2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXG46308.1 - 0.00017 21.6 0.0 0.00042 20.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXG46308.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KXG46308.1 - 0.0037 17.2 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein NAT PF04768.13 KXG46309.1 - 1.5e-52 177.7 0.0 4.6e-51 172.9 0.0 2.5 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase GFA PF04828.14 KXG46310.1 - 5.5e-24 84.3 0.8 1.1e-23 83.4 0.3 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme F-box-like PF12937.7 KXG46310.1 - 0.0021 17.9 0.0 0.0071 16.2 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXG46310.1 - 0.0091 15.9 0.1 0.022 14.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain zinc_ribbon_2 PF13240.6 KXG46310.1 - 2 8.2 10.2 2.1 8.1 1.3 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Peptidase_M24 PF00557.24 KXG46311.1 - 9e-58 195.4 0.0 1.2e-57 195.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXG46311.1 - 2.1e-23 82.4 0.0 3.9e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HIG_1_N PF04588.13 KXG46312.1 - 4e-06 26.9 0.6 6.3e-06 26.3 0.6 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF3683 PF12447.8 KXG46312.1 - 0.056 13.6 0.0 0.062 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) Iso_dh PF00180.20 KXG46313.1 - 1e-127 426.1 0.0 1.1e-127 425.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ANAPC10 PF03256.16 KXG46314.1 - 5.1e-43 146.9 0.0 7.9e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) TPP_enzyme_N PF02776.18 KXG46316.1 - 3.1e-30 105.0 0.0 5.2e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXG46316.1 - 5.5e-16 58.5 0.0 1.1e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KXG46316.1 - 6.2e-16 58.5 0.2 1.7e-15 57.1 0.1 1.8 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain HTH_21 PF13276.6 KXG46317.1 - 0.0007 19.7 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 HTH-like domain adh_short_C2 PF13561.6 KXG46318.1 - 6.1e-59 199.4 3.0 7e-59 199.2 3.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG46318.1 - 8.3e-43 146.1 3.0 1e-42 145.8 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG46318.1 - 5.7e-15 55.7 1.3 7.7e-15 55.3 1.3 1.1 1 0 0 1 1 1 1 KR domain NAD_Gly3P_dh_N PF01210.23 KXG46318.1 - 0.012 15.6 0.2 0.019 15.0 0.2 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DapB_N PF01113.20 KXG46318.1 - 0.038 14.1 0.3 0.23 11.6 0.8 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 3HCDH_N PF02737.18 KXG46318.1 - 0.047 13.6 1.7 0.082 12.8 1.7 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.25 KXG46319.1 - 1.1e-54 185.6 0.0 1.2e-51 175.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG46319.1 - 9.6e-34 116.8 0.0 4.1e-33 114.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG46319.1 - 0.00016 21.1 0.0 0.00024 20.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KXG46319.1 - 0.0012 18.0 0.1 0.0019 17.3 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KXG46319.1 - 0.0026 16.6 0.0 0.0041 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KXG46319.1 - 0.034 13.1 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain GST_N PF02798.20 KXG46320.1 - 1.4e-16 60.6 0.0 4.2e-16 59.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXG46320.1 - 4.2e-14 52.7 0.0 6.9e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXG46320.1 - 4.8e-11 42.7 0.0 9.7e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXG46320.1 - 2.2e-09 37.5 0.0 3.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXG46320.1 - 1.9e-08 34.2 0.1 3.5e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXG46320.1 - 2e-05 24.7 0.0 4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Meth_synt_2 PF01717.18 KXG46321.1 - 5.2e-07 29.2 0.0 1.2e-05 24.8 0.0 2.6 2 1 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Pyr_redox_2 PF07992.14 KXG46322.1 - 6.7e-55 186.4 0.9 1.1e-54 185.7 0.9 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXG46322.1 - 1.6e-30 105.6 0.1 3.4e-30 104.5 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXG46322.1 - 4.7e-14 52.7 0.2 4.7e-14 52.7 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG46322.1 - 2.8e-10 40.0 0.3 4.3e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG46322.1 - 0.0012 18.1 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 KXG46322.1 - 0.033 13.5 0.2 0.045 13.1 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KXG46322.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KXG46322.1 - 1.8 7.6 6.0 12 4.8 0.5 3.0 3 0 0 3 3 3 0 FAD binding domain Amidohydro_2 PF04909.14 KXG46323.1 - 7.5e-25 88.3 0.0 8.3e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Sugar_tr PF00083.24 KXG46324.1 - 5.4e-80 269.4 16.3 6.8e-80 269.1 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG46324.1 - 5.5e-17 61.7 18.9 5.5e-17 61.7 18.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Dynein_AAA_lid PF17852.1 KXG46324.1 - 0.039 14.0 1.2 0.43 10.7 0.0 2.8 4 0 0 4 4 4 0 Dynein heavy chain AAA lid domain DEAD PF00270.29 KXG46325.1 - 1.5e-45 155.1 0.0 2.5e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG46325.1 - 2.8e-30 104.9 0.1 7.5e-29 100.3 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Fungal_trans PF04082.18 KXG46325.1 - 2.9e-24 85.5 0.2 7e-24 84.3 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain UTP25 PF06862.12 KXG46325.1 - 0.0014 17.5 1.0 0.0041 16.0 0.1 2.1 2 1 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CcmH PF03918.14 KXG46325.1 - 0.14 11.4 0.1 0.45 9.8 0.1 1.8 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Acetyltransf_4 PF13420.7 KXG46326.1 - 1.7e-05 25.0 0.0 7.5e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4045 PF13254.6 KXG46327.1 - 4.7e-107 359.2 49.1 5.1e-63 214.2 28.6 6.4 3 3 1 4 4 4 2 Domain of unknown function (DUF4045) Arf PF00025.21 KXG46327.1 - 7.9e-53 178.5 1.7 1.2e-52 177.9 1.1 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KXG46327.1 - 5e-13 49.3 0.1 4.1e-10 39.9 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KXG46327.1 - 1.1e-09 38.0 1.7 9.9e-06 24.9 0.4 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KXG46327.1 - 1.3e-09 37.8 0.1 2.5e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Gelsolin PF00626.22 KXG46327.1 - 4.4e-09 36.1 0.0 0.00094 19.0 0.0 3.7 3 0 0 3 3 3 2 Gelsolin repeat Ras PF00071.22 KXG46327.1 - 2.3e-07 30.6 0.1 4.8e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KXG46327.1 - 8.1e-06 25.9 0.0 1.7e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXG46327.1 - 6.1e-05 22.5 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KXG46327.1 - 0.04 13.4 0.1 0.22 11.0 0.1 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain ALO PF04030.14 KXG46328.1 - 7.5e-90 301.3 0.1 1.1e-89 300.7 0.1 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KXG46328.1 - 6.8e-33 113.4 0.1 1.1e-32 112.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.18 KXG46329.1 - 2.9e-08 33.7 13.9 5.6e-08 32.8 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_2 PF07883.11 KXG46329.1 - 2 8.2 5.2 9.7 6.0 1.2 2.4 2 0 0 2 2 2 0 Cupin domain E1-E2_ATPase PF00122.20 KXG46330.1 - 6.7e-34 117.0 18.5 1.5e-28 99.5 0.1 3.5 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXG46330.1 - 6.7e-27 94.4 10.7 6.7e-27 94.4 10.7 2.8 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KXG46330.1 - 2.9e-17 62.1 0.0 5.6e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KXG46330.1 - 1.4e-16 61.4 0.4 5.1e-15 56.3 0.4 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXG46330.1 - 3.9e-15 55.7 0.0 7.5e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXG46330.1 - 0.00013 21.8 0.3 0.00092 19.0 0.6 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DnaJ PF00226.31 KXG46331.1 - 9.1e-17 60.9 0.5 2.4e-16 59.6 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KXG46331.1 - 6.2e-10 38.7 0.0 6.6e-09 35.3 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain RRN3 PF05327.11 KXG46331.1 - 8.3 4.8 7.2 12 4.3 7.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDP-OH_P_transf PF01066.21 KXG46334.1 - 5.9e-13 49.4 0.5 5.9e-13 49.4 0.5 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PP2C PF00481.21 KXG46335.1 - 4.2e-32 111.8 0.0 9.6e-27 94.2 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KXG46335.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C RRM_1 PF00076.22 KXG46336.1 - 6e-43 144.5 0.8 2e-21 75.6 0.2 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KXG46336.1 - 1.9e-22 80.1 0.4 6e-22 78.5 0.1 2.1 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 KXG46336.1 - 0.00087 19.1 0.0 0.015 15.1 0.0 2.6 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KXG46336.1 - 0.0026 17.4 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXG46336.1 - 0.053 13.6 0.1 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 KXG46336.1 - 0.081 13.1 0.1 21 5.3 0.0 2.8 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 KXG46336.1 - 0.14 12.2 0.2 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif Cyt-b5 PF00173.28 KXG46337.1 - 6.1e-18 64.7 0.1 6.1e-18 64.7 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KXG46337.1 - 5.8e-13 49.3 18.2 1.5e-12 48.0 17.6 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KXG46337.1 - 0.0031 17.7 0.1 0.0063 16.7 0.1 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region ATP-synt_I PF03899.15 KXG46337.1 - 0.0064 16.8 4.1 0.45 10.9 0.1 2.2 2 0 0 2 2 2 2 ATP synthase I chain OMPdecase PF00215.24 KXG46338.1 - 0.00014 21.5 0.0 0.00057 19.6 0.0 1.9 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Fungal_trans PF04082.18 KXG46340.1 - 1e-22 80.5 0.6 1.7e-22 79.7 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG46340.1 - 3.4e-05 23.9 16.2 9.6e-05 22.4 16.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adap_comp_sub PF00928.21 KXG46341.1 - 1.5e-18 67.2 0.0 2.1e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXG46341.1 - 6.5e-07 29.4 0.3 1.1e-06 28.6 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 KXG46341.1 - 0.0038 17.6 0.2 0.0077 16.6 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) DUF2420 PF10336.9 KXG46342.1 - 7.5e-07 29.1 0.2 5.1e-05 23.2 0.0 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2420) Mg_trans_NIPA PF05653.14 KXG46343.1 - 1.3e-97 326.4 22.6 1.9e-95 319.4 22.6 2.0 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXG46343.1 - 0.00024 21.3 8.1 0.00024 21.3 8.1 3.3 3 0 0 3 3 3 3 EamA-like transporter family Syja_N PF02383.18 KXG46344.1 - 6.9e-93 311.5 0.0 1e-92 310.9 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KXG46344.1 - 6e-38 129.1 0.0 1.2e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase DUF3246 PF11596.8 KXG46344.1 - 2.9 7.3 6.5 0.21 11.0 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) HEAT_EZ PF13513.6 KXG46345.1 - 2.5e-35 120.4 3.7 2.2e-14 53.6 0.2 8.5 9 0 0 9 9 8 5 HEAT-like repeat HEAT PF02985.22 KXG46345.1 - 4.9e-20 69.9 14.5 0.0022 18.1 0.0 11.5 12 0 0 12 12 12 5 HEAT repeat HEAT_2 PF13646.6 KXG46345.1 - 2.7e-17 62.9 2.1 4.8e-05 23.7 0.1 8.0 6 3 2 9 9 8 4 HEAT repeats Cnd1 PF12717.7 KXG46345.1 - 8.5e-14 51.9 0.1 6.6e-06 26.3 0.0 4.7 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KXG46345.1 - 1.5e-09 37.0 0.1 0.0021 16.7 0.0 3.6 3 2 2 5 5 5 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KXG46345.1 - 1.1e-08 35.6 0.2 0.26 11.9 0.0 6.5 5 2 2 7 7 7 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KXG46345.1 - 1.8e-06 27.4 3.6 2.1 7.4 0.0 6.2 4 2 1 6 6 6 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KXG46345.1 - 2.5e-06 27.2 0.6 5.3 6.5 0.0 5.9 5 2 2 7 7 7 1 CLASP N terminal IBN_N PF03810.19 KXG46345.1 - 4.8e-05 23.2 0.0 0.0074 16.2 0.0 3.7 2 1 0 2 2 2 1 Importin-beta N-terminal domain DRIM PF07539.12 KXG46345.1 - 0.00031 19.2 0.0 0.45 8.7 0.0 3.2 3 0 0 3 3 3 2 Down-regulated in metastasis HEAT_PBS PF03130.16 KXG46345.1 - 0.0034 17.9 0.6 18 6.3 0.0 5.0 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.9 KXG46345.1 - 0.014 14.0 0.0 0.038 12.5 0.0 1.7 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Arm PF00514.23 KXG46345.1 - 0.023 14.7 3.3 8.4 6.6 0.1 5.0 5 0 0 5 5 4 0 Armadillo/beta-catenin-like repeat DUF3437 PF11919.8 KXG46345.1 - 0.027 14.4 0.2 3.9 7.4 0.0 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF3437) RIX1 PF08167.12 KXG46345.1 - 0.057 13.1 0.1 11 5.6 0.0 4.1 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis TIP120 PF08623.10 KXG46345.1 - 0.14 11.9 0.0 9 6.0 0.0 3.4 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) FANCI_S4 PF14678.6 KXG46345.1 - 0.2 10.8 0.0 0.47 9.5 0.0 1.6 1 0 0 1 1 1 0 FANCI solenoid 4 TAFH PF07531.14 KXG46345.1 - 0.53 10.4 4.1 57 3.9 0.1 4.2 4 0 0 4 4 4 0 NHR1 homology to TAF CVNH PF08881.10 KXG46346.1 - 2.3e-23 82.8 0.0 2.6e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 CVNH domain Zn_clus PF00172.18 KXG46347.1 - 1e-07 32.0 15.7 1.8e-07 31.2 15.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXG46347.1 - 3.4e-05 22.8 5.0 5.8e-05 22.1 4.8 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sigma54_DBD PF04552.13 KXG46347.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54, DNA binding domain TPR_15 PF13429.6 KXG46347.1 - 0.068 12.4 0.2 0.12 11.6 0.2 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_C12 PF01088.21 KXG46348.1 - 2.9e-69 233.0 0.0 3.9e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KXG46348.1 - 2.2e-11 43.4 1.1 2.9e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases Choline_kinase PF01633.20 KXG46349.1 - 2.5e-64 216.8 0.2 6.8e-63 212.1 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 KXG46349.1 - 5.2e-17 61.3 0.0 1e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 KXG46349.1 - 1.7e-05 24.9 0.2 4.4e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Adaptin_binding PF10199.9 KXG46349.1 - 0.02 15.5 2.8 0.21 12.2 2.5 2.4 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 SapB_1 PF05184.15 KXG46349.1 - 0.11 12.5 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 Saposin-like type B, region 1 p450 PF00067.22 KXG46350.1 - 4.5e-50 170.7 0.0 5.4e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GPI-anchored PF10342.9 KXG46351.1 - 0.0035 18.1 0.0 0.0061 17.3 0.0 1.5 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GalBD_like PF17974.1 KXG46351.1 - 0.019 15.1 0.1 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Galactose-binding domain-like Phosphoesterase PF04185.14 KXG46352.1 - 1.2e-71 241.8 5.0 1.7e-71 241.3 5.0 1.2 1 0 0 1 1 1 1 Phosphoesterase family Fascin PF06268.13 KXG46352.1 - 0.022 15.0 0.0 0.1 12.9 0.0 2.0 1 1 1 2 2 2 0 Fascin domain Glyco_transf_90 PF05686.12 KXG46353.1 - 6.7e-21 74.6 2.0 1.4e-17 63.7 0.8 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 90 Taeniidae_ag PF05596.11 KXG46353.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Taeniidae antigen Stn1 PF10451.9 KXG46354.1 - 0.076 12.0 0.3 0.1 11.5 0.3 1.1 1 0 0 1 1 1 0 Telomere regulation protein Stn1 Mem_trans PF03547.18 KXG46355.1 - 2.5e-57 194.1 0.0 3.6e-57 193.5 0.0 1.2 1 0 0 1 1 1 1 Membrane transport protein DUF1240 PF06836.12 KXG46355.1 - 0.52 10.9 4.2 0.18 12.3 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) PS_Dcarbxylase PF02666.15 KXG46356.1 - 2.3e-76 255.8 0.0 6.8e-76 254.3 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase LRR_9 PF14580.6 KXG46357.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat His_Phos_1 PF00300.22 KXG46358.1 - 4.8e-14 52.5 0.0 4.7e-09 36.2 0.0 2.8 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Ribosomal_S8 PF00410.19 KXG46359.1 - 2e-21 76.3 0.0 2.9e-21 75.7 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 HEAT PF02985.22 KXG46360.1 - 2.2e-15 55.4 9.4 0.00072 19.6 0.2 8.7 8 0 0 8 8 8 4 HEAT repeat HEAT_EZ PF13513.6 KXG46360.1 - 1.2e-13 51.3 12.3 1.1e-09 38.6 0.1 6.9 6 2 1 7 7 7 2 HEAT-like repeat IBN_N PF03810.19 KXG46360.1 - 7.3e-08 32.2 5.2 9.8e-07 28.6 0.7 4.1 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KXG46360.1 - 3.9e-06 27.2 8.1 0.1 13.0 0.1 5.8 2 2 3 5 5 5 4 HEAT repeats CLASP_N PF12348.8 KXG46360.1 - 1.1e-05 25.1 0.1 0.069 12.7 0.0 4.1 3 1 0 4 4 4 2 CLASP N terminal DRIM PF07539.12 KXG46360.1 - 8.5e-05 21.1 0.7 2.3 6.4 0.0 4.3 4 0 0 4 4 4 2 Down-regulated in metastasis Dopey_N PF04118.14 KXG46360.1 - 8.6e-05 21.8 1.0 0.0047 16.1 0.1 2.7 3 0 0 3 3 3 1 Dopey, N-terminal DUF3385 PF11865.8 KXG46360.1 - 0.00015 21.7 0.2 1.5 8.7 0.6 4.0 4 1 0 4 4 4 2 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 KXG46360.1 - 0.0002 21.9 0.2 8.6 7.0 0.0 4.9 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KXG46360.1 - 0.03 12.9 0.6 2.8 6.4 0.0 3.5 2 1 0 4 4 4 0 Adaptin N terminal region Sec7_N PF12783.7 KXG46360.1 - 0.066 13.1 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Cse1 PF08506.10 KXG46360.1 - 0.069 12.0 0.1 0.7 8.7 0.1 2.6 2 1 2 4 4 4 0 Cse1 HEAT_PBS PF03130.16 KXG46360.1 - 0.12 13.1 1.5 72 4.5 0.0 4.8 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat Arm PF00514.23 KXG46360.1 - 1.5 9.0 8.6 11 6.2 0.3 4.6 5 0 0 5 5 4 0 Armadillo/beta-catenin-like repeat p450 PF00067.22 KXG46361.1 - 3.4e-51 174.5 0.0 4e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2855 PF11017.8 KXG46361.1 - 0.048 13.4 0.1 0.071 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) DUF4866 PF16160.5 KXG46361.1 - 0.21 10.9 0.0 0.43 9.9 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4866) NmrA PF05368.13 KXG46362.1 - 2e-14 53.7 0.0 2.9e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG46362.1 - 2.9e-05 24.0 0.0 6.7e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KXG46362.1 - 0.016 15.7 0.5 0.16 12.5 0.1 2.6 2 2 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Ank_2 PF12796.7 KXG46363.1 - 1.2e-75 250.1 24.6 1.4e-15 57.6 0.5 5.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG46363.1 - 9.5e-38 128.1 0.0 1.6e-07 31.7 0.0 6.2 1 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG46363.1 - 5.4e-25 84.7 0.4 0.019 15.5 0.0 10.2 10 0 0 10 10 9 6 Ankyrin repeat Ank_5 PF13857.6 KXG46363.1 - 1.4e-23 82.6 12.4 0.002 18.4 0.1 8.5 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KXG46363.1 - 5.4e-21 74.1 7.8 0.054 14.0 0.0 9.7 10 0 0 10 10 9 5 Ankyrin repeat NACHT PF05729.12 KXG46363.1 - 4e-08 33.3 0.0 9.1e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXG46363.1 - 0.00014 22.1 0.0 0.0005 20.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KXG46363.1 - 0.00027 20.2 0.0 0.00072 18.8 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KXG46363.1 - 0.00034 21.0 0.4 0.0017 18.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KXG46363.1 - 0.0079 16.2 0.0 0.51 10.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain Goodbye PF17109.5 KXG46363.1 - 0.053 14.0 0.4 0.053 14.0 0.4 2.1 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain TAXi_C PF14541.6 KXG46363.1 - 0.099 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal FliJ PF02050.16 KXG46363.1 - 0.38 11.0 5.4 1.2 9.4 5.4 1.9 1 0 0 1 1 1 0 Flagellar FliJ protein ANAPC4 PF12896.7 KXG46364.1 - 7.9e-69 231.2 0.8 1.1e-68 230.7 0.8 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KXG46364.1 - 1.1e-34 118.6 0.0 2.6e-33 114.2 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain HpaP PF09483.10 KXG46364.1 - 0.019 15.2 0.1 0.046 14.0 0.1 1.7 1 0 0 1 1 1 0 Type III secretion protein (HpaP) IKI3 PF04762.12 KXG46364.1 - 0.082 10.9 0.0 3.7 5.4 0.0 2.1 2 0 0 2 2 2 0 IKI3 family WD40 PF00400.32 KXG46364.1 - 0.097 13.6 1.7 0.81 10.7 0.0 3.3 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF4739 PF15893.5 KXG46364.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4739) VWA PF00092.28 KXG46366.1 - 0.0029 17.9 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXG46366.1 - 0.073 13.7 0.0 0.22 12.2 0.0 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain Fungal_trans_2 PF11951.8 KXG46367.1 - 7.4e-09 34.9 7.3 1.4e-07 30.7 1.0 3.3 2 2 1 3 3 3 2 Fungal specific transcription factor domain Transgly_assoc PF04226.13 KXG46367.1 - 0.039 14.2 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 Transglycosylase associated protein DUF2298 PF10060.9 KXG46367.1 - 0.087 11.5 0.4 0.22 10.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized membrane protein (DUF2298) zinc_ribbon_2 PF13240.6 KXG46368.1 - 0.022 14.5 0.3 0.05 13.3 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain GFA PF04828.14 KXG46368.1 - 0.067 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme HLH PF00010.26 KXG46369.1 - 8.2e-09 35.3 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Maf PF02545.14 KXG46370.1 - 1.1e-48 165.2 0.0 1.3e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein CybS PF05328.12 KXG46371.1 - 1.9e-50 170.0 0.0 2.4e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit ADH_zinc_N PF00107.26 KXG46372.1 - 1.9e-23 82.9 0.1 2.8e-23 82.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KXG46372.1 - 1.6e-19 69.8 0.0 2.7e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KXG46372.1 - 3e-08 34.8 0.0 6.3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase APH PF01636.23 KXG46373.1 - 5.7e-05 23.2 0.0 0.00063 19.7 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Msg2_C PF12373.8 KXG46373.1 - 0.38 10.2 3.3 0.26 10.8 0.3 2.0 2 0 0 2 2 2 0 Major surface glycoprotein 2 C terminal Pyr_redox_2 PF07992.14 KXG46374.1 - 8.7e-38 130.2 0.0 1.1e-37 129.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG46374.1 - 5.5e-12 46.1 0.6 9.7e-10 38.9 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXG46374.1 - 1.6e-06 27.4 2.3 0.00023 20.4 0.0 3.3 2 1 0 3 3 3 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KXG46374.1 - 0.00034 20.1 0.1 0.2 11.0 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXG46374.1 - 0.0032 16.8 2.8 0.017 14.4 2.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG46374.1 - 0.0037 16.5 0.9 0.19 10.9 0.1 2.5 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KXG46374.1 - 0.0061 16.2 2.8 6.4 6.2 0.0 3.7 3 1 1 4 4 4 2 FAD dependent oxidoreductase CheD PF03975.13 KXG46374.1 - 0.13 12.3 0.4 1.3 9.1 0.1 2.3 2 0 0 2 2 2 0 CheD chemotactic sensory transduction 30K_MP_C_Ter PF11330.8 KXG46374.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins K_oxygenase PF13434.6 KXG46374.1 - 0.2 10.7 0.2 23 4.0 0.0 2.9 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF4246 PF14033.6 KXG46375.1 - 2.2e-48 165.5 5.4 5e-27 95.1 0.8 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) DEAD PF00270.29 KXG46376.1 - 9.1e-43 146.0 0.0 1.4e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG46376.1 - 5.4e-18 65.4 0.1 1.8e-17 63.7 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG46376.1 - 0.00043 20.3 0.0 0.00072 19.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXG46376.1 - 0.061 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SecA_DEAD PF07517.14 KXG46376.1 - 0.09 12.1 0.0 0.24 10.6 0.0 1.7 2 0 0 2 2 2 0 SecA DEAD-like domain Adenylsucc_synt PF00709.21 KXG46377.1 - 4.3e-167 556.3 0.0 4.9e-167 556.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase KHA PF11834.8 KXG46377.1 - 0.067 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel DnaJ PF00226.31 KXG46378.1 - 7e-21 74.1 0.5 1.5e-20 73.0 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.18 KXG46379.1 - 7.2e-27 94.1 0.0 1.4e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG46379.1 - 1e-08 35.2 11.3 1.6e-08 34.5 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SpecificRecomb PF10136.9 KXG46380.1 - 0.012 14.0 0.9 0.014 13.7 0.9 1.1 1 0 0 1 1 1 0 Site-specific recombinase DNA_pol3_tau_5 PF12170.8 KXG46380.1 - 0.026 14.6 2.2 0.047 13.8 2.2 1.4 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha DUF762 PF05555.11 KXG46380.1 - 0.053 13.1 0.2 0.079 12.5 0.2 1.4 1 1 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF762) V_ATPase_I PF01496.19 KXG46380.1 - 0.098 10.6 4.8 0.13 10.2 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MscS_porin PF12795.7 KXG46380.1 - 0.11 12.0 11.0 0.16 11.5 11.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Med9 PF07544.13 KXG46380.1 - 0.12 12.5 8.2 0.92 9.6 5.1 2.8 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 XhlA PF10779.9 KXG46380.1 - 0.72 10.1 3.9 1.5 9.1 0.9 2.3 2 0 0 2 2 2 0 Haemolysin XhlA DUF16 PF01519.16 KXG46380.1 - 3.3 8.3 9.7 8.7 6.9 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 GTP1_OBG PF01018.22 KXG46381.1 - 4.7e-41 139.9 2.2 1.5e-31 109.1 3.0 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KXG46381.1 - 3.9e-22 78.5 0.0 8.4e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXG46381.1 - 1.3e-08 34.5 0.2 8.8e-08 31.8 0.0 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KXG46381.1 - 0.0042 16.1 0.1 1.4 7.8 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KXG46381.1 - 0.005 16.4 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KXG46381.1 - 0.005 17.4 0.6 0.031 14.8 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Ploopntkinase3 PF18751.1 KXG46381.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Dynamin_N PF00350.23 KXG46381.1 - 0.2 11.7 0.4 3.3 7.7 0.0 2.5 3 0 0 3 3 3 0 Dynamin family Cupin_8 PF13621.6 KXG46382.1 - 7.4e-31 107.8 0.0 1.4e-30 106.8 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KXG46382.1 - 4.3e-05 23.1 0.1 0.015 14.8 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 KXG46382.1 - 0.02 15.3 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 KXG46382.1 - 0.068 12.9 0.1 0.32 10.7 0.0 2.2 2 0 0 2 2 2 0 Cupin domain CDC45 PF02724.14 KXG46383.1 - 2.8e-244 812.2 7.6 1.7e-242 806.3 7.6 3.0 1 1 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.12 KXG46383.1 - 0.015 15.0 23.5 0.011 15.4 8.2 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Tir_receptor_N PF07490.11 KXG46383.1 - 0.041 13.7 1.1 0.14 12.0 1.1 1.8 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus BUD22 PF09073.10 KXG46383.1 - 0.07 12.5 36.2 0.03 13.7 16.1 2.2 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 KXG46383.1 - 0.2 9.8 26.5 0.15 10.3 11.0 2.1 2 0 0 2 2 2 0 Nop14-like family DDHD PF02862.17 KXG46383.1 - 1.1 9.4 6.1 0.3 11.2 0.6 2.2 2 0 0 2 2 2 0 DDHD domain DUF5421 PF17458.2 KXG46383.1 - 2.6 7.4 8.4 5 6.4 8.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5421) SDA1 PF05285.12 KXG46383.1 - 7.2 5.9 31.8 5.6 6.3 8.1 2.2 2 0 0 2 2 2 0 SDA1 Nop25 PF09805.9 KXG46383.1 - 7.6 7.0 29.1 8.2 6.9 16.5 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) RR_TM4-6 PF06459.12 KXG46383.1 - 7.8 6.2 22.9 0.19 11.5 10.1 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 KXG46383.1 - 8.6 6.3 15.0 0.067 13.2 4.1 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Spore_coat_CotO PF14153.6 KXG46383.1 - 10 6.0 16.5 0.17 11.8 8.7 1.8 2 0 0 2 2 2 0 Spore coat protein CotO Peptidase_C13 PF01650.18 KXG46384.1 - 7.5e-40 137.1 0.1 1e-39 136.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Ccdc124 PF06244.12 KXG46385.1 - 2.2e-28 99.4 33.0 4.9e-28 98.3 28.5 2.4 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 WD40 PF00400.32 KXG46386.1 - 2.5e-15 56.6 14.4 0.0012 19.6 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat 2OG-FeII_Oxy_2 PF13532.6 KXG46388.1 - 3.5e-37 128.5 0.3 4.7e-37 128.1 0.3 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KXG46388.1 - 0.00019 21.4 3.2 0.00034 20.6 3.2 1.4 1 0 0 1 1 1 1 GRF zinc finger GMC_oxred_N PF00732.19 KXG46389.1 - 2.4e-60 204.4 0.0 3.5e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG46389.1 - 9.8e-35 120.2 0.1 1.7e-34 119.4 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXG46389.1 - 1.5e-05 24.3 0.0 0.021 13.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXG46389.1 - 2.8e-05 23.9 0.1 0.053 13.1 0.0 2.7 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG46389.1 - 0.017 15.4 0.1 0.051 13.8 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXG46389.1 - 0.028 13.5 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KXG46389.1 - 0.03 13.6 0.2 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KXG46389.1 - 0.13 10.9 0.1 0.26 9.9 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein UQ_con PF00179.26 KXG46390.1 - 2.8e-10 40.0 0.0 4.9e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FA_desaturase PF00487.24 KXG46391.1 - 1.7e-22 80.5 18.3 3.5e-22 79.5 18.3 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KXG46391.1 - 8.2e-06 26.0 0.0 2.1e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF4552 PF15089.6 KXG46391.1 - 8.1 5.4 5.3 12 4.9 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) Rad51 PF08423.11 KXG46392.1 - 3.4e-44 151.0 0.0 2.7e-40 138.2 0.0 2.1 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 KXG46392.1 - 1.6e-10 40.9 0.0 3.2e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KXG46392.1 - 9.5e-08 31.7 0.1 7.3e-07 28.8 0.1 2.2 1 1 0 1 1 1 1 KaiC RecA PF00154.21 KXG46392.1 - 4.9e-06 26.2 0.0 1.3e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 recA bacterial DNA recombination protein NACHT PF05729.12 KXG46392.1 - 0.0054 16.7 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DnaB_C PF03796.15 KXG46392.1 - 0.02 14.2 0.1 0.55 9.5 0.1 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_22 PF13401.6 KXG46392.1 - 0.035 14.4 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 KXG46392.1 - 0.092 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.6 KXG46392.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Velvet PF11754.8 KXG46393.1 - 2.6e-50 171.7 0.0 2e-31 109.8 0.0 3.2 2 2 1 3 3 3 2 Velvet factor MFS_1 PF07690.16 KXG46395.1 - 2.6e-19 69.4 46.8 1.9e-10 40.2 20.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Asp PF00026.23 KXG46395.1 - 3e-19 69.6 0.0 1.3e-18 67.5 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXG46395.1 - 0.025 14.8 0.0 0.084 13.1 0.0 1.9 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal Cyclase PF04199.13 KXG46396.1 - 1.1e-11 45.1 0.1 1.9e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Putative cyclase LSM14 PF12701.7 KXG46397.1 - 1.4e-27 95.6 0.0 2.4e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KXG46397.1 - 8e-19 68.4 3.5 8e-19 68.4 3.5 1.9 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 KXG46397.1 - 4.2e-06 26.8 0.0 7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain ATP-synt PF00231.19 KXG46397.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 ATP synthase LSM PF01423.22 KXG46397.1 - 0.27 11.0 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 LSM domain TFIIA PF03153.13 KXG46397.1 - 1 9.3 18.8 1.7 8.6 18.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 KXG46398.1 - 8.7e-24 83.3 4.6 5.3e-06 27.1 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG46398.1 - 4.6e-06 26.8 0.0 0.037 14.3 0.0 3.9 3 2 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Reg_prop PF07494.11 KXG46398.1 - 0.0011 18.9 0.0 1 9.8 0.0 3.1 2 0 0 2 2 2 2 Two component regulator propeller BRK PF07533.16 KXG46398.1 - 0.0071 15.9 0.1 32 4.2 0.0 3.9 3 0 0 3 3 3 0 BRK domain Nup160 PF11715.8 KXG46398.1 - 0.079 11.6 0.0 0.9 8.1 0.0 2.4 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KXG46398.1 - 0.14 12.7 2.4 12 6.6 0.0 4.2 4 1 1 5 5 5 0 PQQ-like domain Sigma70_r1_2 PF00140.20 KXG46398.1 - 0.23 11.5 3.3 0.14 12.2 1.0 1.9 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 Thioredox_DsbH PF03190.15 KXG46399.1 - 1e-71 240.2 0.1 1.7e-71 239.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KXG46399.1 - 5.8e-06 26.4 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_9 PF00759.19 KXG46399.1 - 0.00053 19.5 0.1 0.00095 18.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_127 PF07944.12 KXG46399.1 - 0.0084 14.6 0.4 2 6.8 0.2 2.2 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 KXG46399.1 - 0.012 14.8 0.2 4.6 6.2 0.3 3.2 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 KXG46399.1 - 0.19 11.2 1.3 20 4.6 0.4 2.7 3 0 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus CAP PF00188.26 KXG46400.1 - 1.6e-17 64.5 1.5 3.3e-17 63.5 1.5 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Carn_acyltransf PF00755.20 KXG46401.1 - 2.4e-210 700.1 0.0 1.1e-209 698.0 0.0 1.8 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase RTA1 PF04479.13 KXG46402.1 - 1e-65 221.3 6.5 1.2e-65 221.0 6.5 1.0 1 0 0 1 1 1 1 RTA1 like protein DHHC PF01529.20 KXG46402.1 - 4.3 7.5 6.7 1.1 9.4 1.1 2.4 2 1 1 3 3 3 0 DHHC palmitoyltransferase Jak1_Phl PF17887.1 KXG46404.1 - 0.032 14.2 1.9 0.045 13.7 1.9 1.2 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain Rad60-SLD PF11976.8 KXG46405.1 - 8.1e-20 70.4 0.3 9.4e-20 70.2 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXG46405.1 - 2.3e-10 40.1 0.1 2.6e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Nup84_Nup100 PF04121.13 KXG46406.1 - 9.4e-172 572.8 0.5 1.4e-171 572.2 0.5 1.3 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 CDC45 PF02724.14 KXG46406.1 - 0.058 11.7 13.6 0.093 11.0 13.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KXG46406.1 - 0.29 9.3 17.7 0.47 8.6 17.7 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KXG46406.1 - 0.47 9.8 17.1 0.87 8.9 17.1 1.3 1 0 0 1 1 1 0 SDA1 Cation_ATPase_C PF00689.21 KXG46407.1 - 1.4e-46 158.6 9.0 1.4e-46 158.6 9.0 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXG46407.1 - 1.4e-39 135.4 0.6 1.4e-39 135.4 0.6 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXG46407.1 - 2.7e-19 69.0 0.0 5.4e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXG46407.1 - 9e-19 68.6 0.8 7.5e-18 65.6 0.8 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXG46407.1 - 3.1e-09 36.4 0.1 1.2e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXG46407.1 - 9e-05 22.3 2.0 0.00029 20.7 1.7 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 KXG46407.1 - 0.13 11.1 3.2 0.31 9.8 3.2 1.6 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG APH PF01636.23 KXG46408.1 - 2e-14 54.1 0.0 4.3e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG46408.1 - 0.01 15.4 0.0 0.031 13.9 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 KXG46408.1 - 0.096 12.0 0.0 0.92 8.8 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Med9 PF07544.13 KXG46408.1 - 0.1 12.7 0.3 12 6.0 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Fructosamin_kin PF03881.14 KXG46408.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase DUF1679 PF07914.11 KXG46408.1 - 0.15 10.8 0.0 0.53 9.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) D-ser_dehydrat PF14031.6 KXG46409.1 - 6e-23 81.3 0.1 1.7e-22 79.8 0.1 1.8 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KXG46409.1 - 1.1e-11 44.8 0.0 1.6e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Transp_cyt_pur PF02133.15 KXG46411.1 - 5.7e-16 58.3 42.2 1.3e-15 57.1 42.2 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF5418 PF17439.2 KXG46411.1 - 1.6 8.8 6.0 0.19 11.8 0.5 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5418) DUF2236 PF09995.9 KXG46412.1 - 2e-07 31.4 0.2 3.2e-07 30.8 0.2 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) AGT PF11440.8 KXG46412.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Tubulin PF00091.25 KXG46413.1 - 5.9e-68 229.0 0.0 1.3e-67 227.8 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXG46413.1 - 2.2e-43 147.4 0.0 4.3e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KXG46413.1 - 2.6e-05 24.5 0.0 6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KXG46413.1 - 0.0014 17.9 0.1 0.025 13.8 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KXG46413.1 - 0.0027 17.4 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.22 KXG46414.1 - 7.3e-16 57.7 0.0 3e-06 27.0 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YPEB PF14620.6 KXG46414.1 - 0.0021 17.5 1.3 0.0038 16.6 1.3 1.3 1 0 0 1 1 1 1 YpeB sporulation M16C_assoc PF08367.11 KXG46414.1 - 0.0094 15.1 0.2 0.015 14.5 0.2 1.3 1 0 0 1 1 1 1 Peptidase M16C associated RRM_7 PF16367.5 KXG46414.1 - 0.025 14.7 0.0 0.075 13.2 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif DUF4731 PF15875.5 KXG46414.1 - 0.16 12.1 0.2 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4731) NAD_binding_1 PF00175.21 KXG46415.1 - 2.1e-16 60.5 0.0 4.9e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KXG46415.1 - 8.2e-10 39.2 0.1 2.4e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.12 KXG46415.1 - 2.7e-05 24.4 0.0 0.00034 20.7 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 KXG46415.1 - 0.00012 22.0 0.1 0.00021 21.2 0.1 1.3 1 0 0 1 1 1 1 Protoglobin Cu-oxidase_2 PF07731.14 KXG46418.1 - 5.7e-12 45.6 0.3 5.6e-05 22.9 0.0 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXG46418.1 - 1e-11 44.9 0.6 3.3e-08 33.5 0.2 2.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KXG46418.1 - 1.4e-05 25.2 0.0 7.7e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cupredoxin_1 PF13473.6 KXG46418.1 - 0.025 14.7 0.0 6.4 6.9 0.0 2.7 2 1 0 2 2 2 0 Cupredoxin-like domain Ammonium_transp PF00909.21 KXG46419.1 - 1.2e-121 406.2 31.8 1.3e-121 406.0 31.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF441 PF04284.13 KXG46419.1 - 0.13 12.3 5.0 0.19 11.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF441) Pkinase PF00069.25 KXG46420.1 - 1.3e-65 221.4 0.0 2.2e-65 220.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG46420.1 - 8.8e-36 123.5 0.0 4.5e-33 114.6 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG46420.1 - 0.001 18.4 0.3 0.021 14.1 0.4 2.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXG46420.1 - 0.0032 17.4 0.0 0.0072 16.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXG46420.1 - 0.0042 15.9 0.0 0.0079 15.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KXG46420.1 - 0.01 14.9 0.1 0.02 14.0 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FtsX_ECD PF18075.1 KXG46420.1 - 0.046 14.3 0.0 0.22 12.2 0.0 2.2 2 0 0 2 2 2 0 FtsX extracellular domain FERM_f0 PF16511.5 KXG46420.1 - 0.083 13.2 0.1 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM YrbL-PhoP_reg PF10707.9 KXG46420.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Vta1_C PF18097.1 KXG46420.1 - 0.18 11.6 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Vta1 C-terminal domain Vac_ImportDeg PF09783.9 KXG46421.1 - 3.7e-69 231.7 1.1 4.5e-69 231.4 1.1 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.14 KXG46422.1 - 2.2e-73 245.0 0.3 2.5e-73 244.9 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein PDZ_4 PF17816.1 KXG46422.1 - 0.12 12.8 0.1 3.7 8.0 0.1 2.2 1 1 0 2 2 2 0 PDZ domain Adaptin_N PF01602.20 KXG46423.1 - 2.8e-91 306.7 13.3 4.4e-91 306.0 13.3 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KXG46423.1 - 9.3e-58 194.1 0.8 2.1e-57 192.9 0.8 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KXG46423.1 - 3e-56 188.9 0.0 9.2e-56 187.3 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KXG46423.1 - 3.7e-11 43.3 7.2 6.8e-09 36.0 0.0 3.4 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXG46423.1 - 1.6e-08 34.8 11.3 0.00028 21.2 0.0 5.4 3 1 3 6 6 6 4 HEAT repeats Coatomer_g_Cpla PF16381.5 KXG46423.1 - 9.6e-05 22.5 0.0 0.00062 19.9 0.0 2.4 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 KXG46423.1 - 0.00025 21.0 0.6 1.1 9.8 0.1 4.7 4 0 0 4 4 4 1 HEAT repeat AP4E_app_platf PF14807.6 KXG46423.1 - 0.0045 17.3 0.2 0.016 15.5 0.2 2.1 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform HEAT_EZ PF13513.6 KXG46423.1 - 0.038 14.5 1.0 2.5 8.7 0.0 4.2 3 1 2 5 5 5 0 HEAT-like repeat RTP1_C1 PF10363.9 KXG46423.1 - 0.041 14.1 3.6 4.6 7.5 0.3 3.7 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KXG46423.1 - 0.33 11.0 3.4 2.2 8.5 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DAGK_cat PF00781.24 KXG46424.1 - 3.6e-24 84.8 0.0 5.8e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Nop52 PF05997.12 KXG46425.1 - 1.2e-51 175.6 0.5 1.5e-50 172.0 0.5 2.0 1 1 0 1 1 1 1 Nucleolar protein,Nop52 NOT2_3_5 PF04153.18 KXG46425.1 - 0.04 14.0 0.1 0.078 13.1 0.1 1.4 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family HEAT PF02985.22 KXG46425.1 - 0.053 13.8 0.0 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat RAP1 PF07218.11 KXG46425.1 - 0.059 11.6 0.2 0.086 11.1 0.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CMS1 PF14617.6 KXG46425.1 - 0.33 10.3 4.4 2.6 7.3 4.4 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit ORC_WH_C PF18137.1 KXG46425.1 - 1.6 8.8 5.8 3.2 7.8 4.8 1.9 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal HATPase_c PF02518.26 KXG46426.1 - 9.6e-25 87.3 0.1 2.4e-24 86.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXG46426.1 - 2.4e-18 66.3 0.1 4.2e-18 65.5 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXG46426.1 - 5.7e-12 45.5 0.0 1.5e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain FAD_binding_3 PF01494.19 KXG46427.1 - 7.9e-14 51.7 0.0 3.3e-13 49.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG46427.1 - 2e-10 40.4 0.0 1.2e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG46427.1 - 3.5e-07 30.1 0.2 4e-05 23.4 0.2 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXG46427.1 - 5.9e-07 28.9 0.0 7.6e-06 25.3 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXG46427.1 - 3.5e-06 27.1 0.1 1.1e-05 25.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXG46427.1 - 3.9e-06 27.3 0.3 0.00011 22.6 0.2 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG46427.1 - 7.7e-05 22.1 0.0 0.0075 15.5 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXG46427.1 - 8.4e-05 22.1 0.1 0.00015 21.2 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXG46427.1 - 8.7e-05 21.8 0.0 0.0025 17.0 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXG46427.1 - 0.00014 21.0 0.0 0.18 10.8 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 KXG46427.1 - 0.00022 20.1 0.3 0.0015 17.3 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KXG46427.1 - 0.002 17.5 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KXG46427.1 - 0.075 13.0 0.1 6.6 6.7 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXG46427.1 - 0.21 10.4 0.6 2.9 6.6 0.1 2.6 3 1 0 3 3 3 0 Tryptophan halogenase DUF3425 PF11905.8 KXG46430.1 - 9.9e-16 57.8 0.1 5.1e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) adh_short PF00106.25 KXG46431.1 - 2e-26 92.7 0.9 5.3e-25 88.0 0.9 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG46431.1 - 2.5e-18 66.5 0.2 2.7e-17 63.1 0.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG46431.1 - 5.9e-05 23.0 0.2 0.0001 22.3 0.2 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXG46431.1 - 0.014 14.9 1.0 0.05 13.0 1.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.22 KXG46432.1 - 7.5e-72 242.5 0.0 9.1e-72 242.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UBD PF16455.5 KXG46433.1 - 5e-42 142.4 0.0 8.1e-42 141.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain DUF2407 PF10302.9 KXG46433.1 - 0.023 15.3 0.1 0.089 13.4 0.0 2.0 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain DUF1604 PF07713.13 KXG46434.1 - 2.6e-40 136.1 1.7 7.8e-40 134.6 1.7 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KXG46434.1 - 1.1e-06 28.4 3.7 1.7e-06 27.8 2.2 2.0 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KXG46434.1 - 0.017 15.2 0.5 0.017 15.2 0.5 3.1 3 1 0 3 3 3 0 G-patch domain Glyco_transf_90 PF05686.12 KXG46435.1 - 5e-11 42.1 5.0 1.7e-05 24.0 1.8 4.2 3 1 0 3 3 3 3 Glycosyl transferase family 90 Pkinase PF00069.25 KXG46436.1 - 3.2e-12 46.4 0.0 4.3e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Glyco_hydro_16 PF00722.21 KXG46437.1 - 3.5e-41 140.6 4.0 3.5e-41 140.6 4.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 CHB_HEX PF03173.13 KXG46437.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative carbohydrate binding domain MFS_1 PF07690.16 KXG46438.1 - 8.4e-37 126.9 18.5 8.4e-37 126.9 18.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG46438.1 - 8e-11 41.5 1.3 8e-11 41.5 1.3 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter PhaG_MnhG_YufB PF03334.14 KXG46438.1 - 0.18 12.1 8.4 17 5.7 0.1 4.1 3 0 0 3 3 3 0 Na+/H+ antiporter subunit DUF5381 PF17353.2 KXG46438.1 - 1.1 9.0 3.8 1.3 8.7 1.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5381) Amino_oxidase PF01593.24 KXG46439.1 - 2e-55 188.9 0.0 3.3e-54 184.9 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXG46439.1 - 4.5e-15 55.6 0.2 8.1e-15 54.8 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG46439.1 - 5.9e-07 29.0 0.2 3.5e-06 26.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG46439.1 - 1.3e-06 28.9 0.4 1.1e-05 25.9 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG46439.1 - 3e-06 27.1 2.6 5e-06 26.3 2.7 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXG46439.1 - 4.9e-06 25.5 0.4 8.1e-06 24.8 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KXG46439.1 - 2.9e-05 23.6 0.4 4.5e-05 23.0 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXG46439.1 - 5.7e-05 22.5 0.1 0.00011 21.6 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KXG46439.1 - 6.5e-05 22.3 0.4 6.5e-05 22.3 0.4 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KXG46439.1 - 0.00018 20.9 0.2 0.00039 19.7 0.2 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KXG46439.1 - 0.00019 20.6 1.1 0.00032 19.9 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.6 KXG46439.1 - 0.00037 19.7 0.3 1.6 7.8 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXG46439.1 - 0.00051 19.4 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXG46439.1 - 0.00085 18.5 1.5 0.0032 16.6 0.8 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A YjeF_N PF03853.15 KXG46439.1 - 0.0093 15.9 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus Glu_dehyd_C PF16912.5 KXG46439.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus 3HCDH_N PF02737.18 KXG46439.1 - 0.025 14.5 0.1 0.042 13.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.19 KXG46439.1 - 0.034 12.6 0.0 0.047 12.1 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 KXG46439.1 - 0.047 13.7 0.2 0.14 12.2 0.2 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MCRA PF06100.11 KXG46439.1 - 0.063 12.1 0.0 0.27 10.0 0.0 1.8 2 0 0 2 2 2 0 MCRA family NAD_binding_9 PF13454.6 KXG46439.1 - 0.072 13.1 0.0 0.75 9.8 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KXG46439.1 - 0.11 12.9 4.4 0.63 10.5 1.1 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding 7tm_1 PF00001.21 KXG46440.1 - 3e-07 30.0 3.3 4.4e-07 29.5 3.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KXG46440.1 - 1.3e-06 28.4 11.7 2.4e-06 27.5 11.7 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 KXG46440.1 - 1.8e-06 27.3 8.1 3.2e-06 26.5 8.1 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7TM_GPCR_Srsx PF10320.9 KXG46440.1 - 0.00089 18.7 6.8 0.0012 18.3 6.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SKA1 PF07160.12 KXG46441.1 - 0.0028 17.5 1.2 0.0038 17.1 1.2 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 RP-C_C PF11800.8 KXG46441.1 - 0.02 15.0 1.8 0.027 14.6 1.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Pep1_7 PF17232.2 KXG46441.1 - 0.047 14.1 9.2 0.1 13.1 9.2 1.6 1 1 0 1 1 1 0 Elicitor peptide 1-7 SpoIIIAH PF12685.7 KXG46441.1 - 0.098 12.5 5.9 0.12 12.2 5.9 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein MMU163 PF17119.5 KXG46441.1 - 0.32 10.1 3.6 0.4 9.8 3.6 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis MID_MedPIWI PF18296.1 KXG46441.1 - 0.35 10.6 6.6 0.43 10.3 6.6 1.1 1 0 0 1 1 1 0 MID domain of medPIWI SR-25 PF10500.9 KXG46441.1 - 0.41 10.2 22.1 0.53 9.9 22.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF842 PF05811.13 KXG46441.1 - 0.61 9.8 9.5 1.1 9.0 6.4 2.2 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) CobT PF06213.12 KXG46441.1 - 6 6.2 11.2 7.8 5.8 11.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT IMUP PF15761.5 KXG46441.1 - 6.5 7.5 25.2 7.8 7.2 22.3 2.1 1 1 1 2 2 2 0 Immortalisation up-regulated protein Presenilin PF01080.17 KXG46441.1 - 8 5.1 6.3 10 4.8 6.3 1.1 1 0 0 1 1 1 0 Presenilin AA_permease PF00324.21 KXG46442.1 - 4.5e-106 355.3 48.1 5.5e-106 355.0 48.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG46442.1 - 4.8e-30 104.7 48.9 6.6e-30 104.3 48.9 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_3 PF13302.7 KXG46443.1 - 5.2e-34 117.9 0.0 6.1e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG46443.1 - 8.4e-08 32.5 0.0 7.9e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXG46443.1 - 0.008 16.6 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG46443.1 - 0.095 12.7 0.0 0.44 10.5 0.0 2.1 3 0 0 3 3 3 0 FR47-like protein GMC_oxred_C PF05199.13 KXG46444.1 - 7.8e-30 104.3 0.0 1.2e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KXG46444.1 - 4.9e-29 101.6 0.0 1e-25 90.8 0.0 2.8 1 1 1 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 KXG46444.1 - 0.0015 18.7 0.9 0.0035 17.5 0.5 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXG46444.1 - 0.012 14.7 0.4 0.021 13.9 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KXG46444.1 - 0.017 14.4 0.0 0.062 12.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXG46444.1 - 0.068 12.2 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXG46444.1 - 0.13 11.5 0.2 3.2 6.9 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.6 KXG46446.1 - 1e-14 54.9 0.4 1.8e-14 54.1 0.1 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KXG46446.1 - 1.4e-10 41.2 0.0 1.8e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KXG46446.1 - 4.4e-08 33.4 0.0 6.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXG46446.1 - 2.1e-05 24.1 0.1 3.1e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXG46446.1 - 0.00063 20.2 0.1 0.0012 19.2 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KXG46446.1 - 0.0034 18.2 0.0 0.0073 17.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold KR PF08659.10 KXG46446.1 - 0.005 16.8 0.1 0.0081 16.1 0.1 1.3 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 KXG46446.1 - 0.0069 16.5 0.1 0.015 15.4 0.1 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.23 KXG46446.1 - 0.033 14.3 0.1 0.072 13.2 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain HicB PF05534.12 KXG46446.1 - 0.037 13.9 0.1 0.076 12.9 0.1 1.5 1 0 0 1 1 1 0 HicB family F420_oxidored PF03807.17 KXG46446.1 - 0.039 14.5 0.1 0.077 13.6 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXG46446.1 - 0.35 10.2 1.1 23 4.3 0.3 2.2 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pigment_DH PF06324.11 KXG46446.1 - 0.92 9.7 3.9 2.8 8.2 0.1 2.9 3 0 0 3 3 3 0 Pigment-dispersing hormone (PDH) EI24 PF07264.11 KXG46448.1 - 4.5e-10 40.1 0.1 1.1e-09 38.8 0.1 1.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) p450 PF00067.22 KXG46449.1 - 1e-52 179.5 0.0 1.5e-52 178.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FSH1 PF03959.13 KXG46450.1 - 1.4e-39 136.0 0.0 1.8e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 KXG46450.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2235 PF09994.9 KXG46450.1 - 0.022 14.1 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2048 PF09752.9 KXG46450.1 - 0.053 12.6 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Abhydrolase domain containing 18 DLH PF01738.18 KXG46450.1 - 0.06 12.9 0.0 0.43 10.1 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Thioesterase PF00975.20 KXG46450.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Acetyltransf_10 PF13673.7 KXG46451.1 - 7.1e-12 45.4 0.0 1.1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG46451.1 - 3.8e-10 40.0 0.0 5.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXG46451.1 - 9e-09 35.6 0.0 1.4e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KXG46451.1 - 0.046 13.4 0.1 0.067 12.9 0.1 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ NAD_binding_10 PF13460.6 KXG46452.1 - 2.4e-08 34.1 0.1 3.5e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXG46452.1 - 5.6e-06 26.0 0.0 1.4e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXG46452.1 - 1.7e-05 24.5 1.3 4.5e-05 23.1 0.1 2.0 2 1 0 2 2 2 1 NmrA-like family HIM1 PF08732.10 KXG46452.1 - 0.0005 19.6 0.0 0.00066 19.2 0.0 1.2 1 0 0 1 1 1 1 HIM1 DapB_N PF01113.20 KXG46452.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KXG46452.1 - 0.069 13.6 0.0 0.12 12.8 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_transf_90 PF05686.12 KXG46453.1 - 3.4e-16 59.1 2.7 7e-10 38.4 0.1 3.1 3 0 0 3 3 3 3 Glycosyl transferase family 90 CRAL_TRIO PF00650.20 KXG46454.1 - 2.9e-24 85.6 0.0 4.2e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXG46454.1 - 0.0027 17.9 0.1 0.01 16.0 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain PKHD_C PF18331.1 KXG46454.1 - 0.057 13.5 0.0 7.7 6.7 0.0 2.5 2 0 0 2 2 2 0 PKHD-type hydroxylase C-terminal domain Goodbye PF17109.5 KXG46455.1 - 8e-36 123.1 0.0 6.8e-35 120.1 0.1 2.6 3 0 0 3 3 3 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 KXG46455.1 - 0.01 15.7 0.0 0.033 14.1 0.0 1.9 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.14 KXG46455.1 - 0.051 12.8 0.1 0.34 10.1 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain TPR_14 PF13428.6 KXG46455.1 - 0.062 14.2 7.1 2.1 9.4 0.0 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat C1_2 PF03107.16 KXG46455.1 - 0.073 13.4 2.7 0.19 12.1 2.7 1.7 1 0 0 1 1 1 0 C1 domain Imm30 PF15565.6 KXG46455.1 - 0.077 13.1 0.0 0.43 10.7 0.0 2.3 1 0 0 1 1 1 0 Immunity protein 30 TPR_12 PF13424.6 KXG46455.1 - 0.14 12.5 10.1 2.5 8.4 0.1 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF1505 PF07403.11 KXG46456.1 - 0.016 15.3 0.6 0.019 15.1 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) MiAMP1 PF09117.10 KXG46456.1 - 0.047 13.9 2.6 0.044 14.0 2.1 1.3 1 1 0 1 1 1 0 MiAMP1 Response_reg PF00072.24 KXG46457.1 - 1e-17 64.3 0.1 9e-17 61.3 0.5 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 KXG46457.1 - 3.1e-17 63.1 0.6 6.6e-17 62.0 0.6 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KXG46457.1 - 1e-10 41.5 0.1 3.7e-10 39.7 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KXG46457.1 - 0.024 14.5 0.1 0.05 13.4 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Acyl_transf_3 PF01757.22 KXG46458.1 - 9.6e-17 61.1 29.9 2.6e-16 59.6 29.9 1.7 1 1 0 1 1 1 1 Acyltransferase family DUF3579 PF12112.8 KXG46458.1 - 0.11 13.1 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) RabGAP-TBC PF00566.18 KXG46459.1 - 2.6e-37 128.6 0.0 2.9e-36 125.1 0.0 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Peptidase_M64 PF09471.10 KXG46459.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 IgA Peptidase M64 SGL PF08450.12 KXG46460.1 - 4.4e-06 26.4 0.2 0.00026 20.7 0.1 2.1 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region bZIP_1 PF00170.21 KXG46461.1 - 5.2e-10 39.3 15.6 9e-10 38.5 14.8 1.7 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KXG46461.1 - 3.2e-05 23.9 11.9 3.2e-05 23.9 11.9 2.0 1 1 1 2 2 2 1 Basic region leucine zipper ATG16 PF08614.11 KXG46461.1 - 0.0013 19.0 8.8 0.0018 18.5 8.8 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) GAS PF13851.6 KXG46461.1 - 0.0025 17.2 9.6 0.0035 16.7 9.6 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TipAS PF07739.13 KXG46461.1 - 0.047 14.2 4.0 0.092 13.3 4.0 1.5 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain DUF848 PF05852.11 KXG46461.1 - 0.05 13.7 4.6 0.072 13.2 4.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Exonuc_VII_L PF02601.15 KXG46461.1 - 0.052 13.1 2.6 0.056 13.0 2.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Troponin PF00992.20 KXG46461.1 - 0.063 13.6 12.0 0.089 13.1 12.0 1.1 1 0 0 1 1 1 0 Troponin Phlebovirus_NSM PF07246.11 KXG46461.1 - 0.072 12.5 2.9 0.086 12.2 2.9 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M HAUS6_N PF14661.6 KXG46461.1 - 0.087 12.4 10.8 0.11 12.0 10.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus WASH-7_N PF14745.6 KXG46461.1 - 0.1 11.1 2.5 0.13 10.7 2.5 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal UPF0242 PF06785.11 KXG46461.1 - 0.15 12.1 8.6 0.22 11.6 8.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 KXG46461.1 - 0.15 12.3 6.4 0.27 11.5 6.4 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PI3K_P85_iSH2 PF16454.5 KXG46461.1 - 0.16 11.6 10.2 0.24 11.0 10.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF948 PF06103.11 KXG46461.1 - 0.18 12.1 0.7 0.28 11.5 0.7 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PRP1_N PF06424.12 KXG46461.1 - 0.21 12.0 3.7 0.29 11.5 3.7 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal CRA PF06589.11 KXG46461.1 - 0.33 11.1 4.1 0.47 10.6 4.1 1.1 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) YabA PF06156.13 KXG46461.1 - 0.79 10.4 6.9 0.14 12.8 2.7 1.8 1 1 1 2 2 2 0 Initiation control protein YabA OmpH PF03938.14 KXG46461.1 - 0.83 10.0 10.6 1.2 9.5 10.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_Maf PF03131.17 KXG46461.1 - 0.85 10.2 15.8 1.1 9.9 15.1 1.5 1 1 0 1 1 1 0 bZIP Maf transcription factor Prominin PF05478.11 KXG46461.1 - 1 7.2 4.2 1.3 6.8 4.2 1.1 1 0 0 1 1 1 0 Prominin ABC_tran_CTD PF16326.5 KXG46461.1 - 1.7 9.0 10.7 2.2 8.6 9.3 1.8 1 1 0 1 1 1 0 ABC transporter C-terminal domain V_ATPase_I PF01496.19 KXG46461.1 - 2.2 6.1 4.7 2.7 5.8 4.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.6 KXG46461.1 - 2.4 8.6 10.8 14 6.2 3.0 2.3 1 1 1 2 2 2 0 Snapin/Pallidin FapA PF03961.13 KXG46461.1 - 3.1 6.3 6.1 4 5.9 6.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 KXG46461.1 - 9.4 6.1 11.0 7 6.5 0.9 2.2 1 1 1 2 2 2 0 Septum formation initiator Fungal_trans_2 PF11951.8 KXG46462.1 - 1.5e-09 37.2 6.3 2e-07 30.2 1.7 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain SR-25 PF10500.9 KXG46462.1 - 0.14 11.8 1.0 0.25 10.9 1.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein COG7 PF10191.9 KXG46462.1 - 2.5 6.2 6.7 0.065 11.5 0.5 1.4 2 0 0 2 2 2 0 Golgi complex component 7 (COG7) Fungal_trans_2 PF11951.8 KXG46463.1 - 0.0012 17.8 0.1 0.021 13.7 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain adh_short PF00106.25 KXG46464.1 - 7.5e-43 146.3 0.2 1e-42 145.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG46464.1 - 2.5e-29 102.5 0.2 3.2e-29 102.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXG46464.1 - 2.3e-05 24.0 0.2 5e-05 22.9 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXG46464.1 - 4.2e-05 23.1 0.0 6.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KXG46464.1 - 0.00048 20.1 0.2 0.00068 19.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Choline_transpo PF04515.12 KXG46465.1 - 1.3e-80 271.0 24.4 1.3e-80 271.0 24.4 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter APH PF01636.23 KXG46465.1 - 8.8e-13 48.7 0.4 2e-12 47.6 0.4 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG46465.1 - 8.4e-06 25.5 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Phage_tail_APC PF16778.5 KXG46465.1 - 0.038 13.9 0.0 0.76 9.7 0.0 2.6 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Pex14_N PF04695.13 KXG46465.1 - 0.38 11.4 8.9 0.85 10.3 8.9 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4956 PF16316.5 KXG46465.1 - 4.6 6.9 8.7 11 5.7 8.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) AAA_33 PF13671.6 KXG46467.1 - 2.4e-17 63.4 0.0 3e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXG46467.1 - 1.5e-05 25.6 0.0 1.9e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KXG46467.1 - 0.00016 20.9 0.0 0.00022 20.5 0.0 1.3 1 1 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.12 KXG46467.1 - 0.0019 17.5 0.0 0.0077 15.5 0.0 1.8 1 1 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 KXG46467.1 - 0.0079 16.6 0.0 0.023 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXG46467.1 - 0.041 14.2 0.0 0.061 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Torsin PF06309.11 KXG46467.1 - 0.08 13.0 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Torsin BRCT PF00533.26 KXG46467.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF3242 PF11586.8 KXG46467.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) Peptidase_C14 PF00656.22 KXG46468.1 - 3.1e-05 24.1 0.1 0.00015 21.9 0.0 1.8 1 1 1 2 2 2 1 Caspase domain Raptor_N PF14538.6 KXG46468.1 - 0.00092 19.2 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Fungal_trans PF04082.18 KXG46469.1 - 6e-10 38.6 0.1 1.2e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXG46470.1 - 7.7e-20 71.1 34.1 9.4e-20 70.8 31.0 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KXG46470.1 - 0.44 8.8 11.9 1 7.6 12.0 1.5 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Ank_2 PF12796.7 KXG46471.1 - 1e-24 86.9 0.0 1.8e-10 41.2 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG46471.1 - 2.1e-17 61.4 0.0 0.0032 17.8 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KXG46471.1 - 4.6e-16 59.0 0.1 7.3e-07 29.6 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG46471.1 - 8.3e-15 54.7 0.1 4.7e-05 23.6 0.0 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KXG46471.1 - 1.4e-13 50.6 0.0 0.0023 18.3 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat APH PF01636.23 KXG46472.1 - 0.00028 20.9 0.0 0.0008 19.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABM PF03992.16 KXG46474.1 - 0.0015 18.6 0.1 0.0019 18.2 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SelP_N PF04592.14 KXG46474.1 - 0.014 14.8 0.3 0.016 14.6 0.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FemAB_like PF04339.12 KXG46474.1 - 0.058 12.5 0.1 0.065 12.4 0.1 1.0 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition BCS1_N PF08740.11 KXG46475.1 - 4.7e-48 163.7 0.2 6.7e-48 163.1 0.2 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KXG46475.1 - 4.9e-18 65.8 0.0 8.9e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXG46475.1 - 0.00011 22.6 0.0 0.00035 21.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 KXG46475.1 - 0.00039 19.7 0.0 0.00067 18.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 KXG46475.1 - 0.0012 18.4 0.0 0.013 15.1 0.0 2.2 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 KXG46475.1 - 0.0017 18.1 0.0 0.062 13.0 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXG46475.1 - 0.006 17.1 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXG46475.1 - 0.0083 16.1 0.0 0.026 14.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KXG46475.1 - 0.0086 16.5 0.0 0.027 14.8 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_25 PF13481.6 KXG46475.1 - 0.012 15.2 0.0 0.17 11.5 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 KXG46475.1 - 0.019 14.7 0.0 0.052 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KXG46475.1 - 0.024 15.2 0.0 0.058 13.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 KXG46475.1 - 0.03 14.2 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXG46475.1 - 0.033 14.5 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 KXG46475.1 - 0.045 13.9 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2735 PF10931.8 KXG46475.1 - 0.076 13.7 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) ATPase PF06745.13 KXG46475.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC MMR_HSR1 PF01926.23 KXG46475.1 - 0.082 13.0 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase PPV_E1_C PF00519.17 KXG46475.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase RuvB_N PF05496.12 KXG46475.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KXG46475.1 - 0.14 12.0 0.0 0.33 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KXG46475.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Lactamase_B_2 PF12706.7 KXG46476.1 - 5.4e-29 101.1 0.0 5.5e-28 97.9 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXG46476.1 - 2.4e-11 43.8 0.0 7.9e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXG46476.1 - 0.00058 19.9 0.1 0.084 12.9 0.1 3.0 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Cpn60_TCP1 PF00118.24 KXG46477.1 - 1.3e-173 578.2 0.4 1.5e-173 578.0 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 KXG46477.1 - 0.085 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 BRK domain DUF1168 PF06658.12 KXG46478.1 - 1.4e-38 131.8 8.0 2e-38 131.3 8.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 KXG46478.1 - 0.047 12.8 0.0 0.068 12.3 0.0 1.1 1 0 0 1 1 1 0 Lyase, catalytic PPL5 PF18168.1 KXG46478.1 - 0.083 12.2 1.7 0.12 11.7 1.7 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Peptidase_S49_N PF08496.10 KXG46478.1 - 0.34 11.0 4.1 0.47 10.5 4.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Nucleo_P87 PF07267.11 KXG46478.1 - 1.5 7.6 9.1 1.9 7.3 9.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 KXG46478.1 - 1.7 6.8 7.7 2.3 6.4 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KXG46478.1 - 3.5 6.3 3.9 3.3 6.4 3.9 1.1 1 0 0 1 1 1 0 Presenilin DUF1682 PF07946.14 KXG46478.1 - 4.8 6.3 11.6 4.8 6.3 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) zf-PARP PF00645.18 KXG46479.1 - 2.8e-25 89.0 0.2 1.5e-24 86.6 0.2 2.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region EspF PF04806.12 KXG46480.1 - 1.3 9.5 6.3 0.32 11.4 1.5 2.5 2 1 1 3 3 3 0 EspF protein repeat ADH_zinc_N PF00107.26 KXG46481.1 - 5.6e-08 32.8 0.0 2.2e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase BTB PF00651.31 KXG46481.1 - 4.2e-06 26.9 0.0 1.9e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Lipase_3 PF01764.25 KXG46482.1 - 8e-16 58.2 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KXG46482.1 - 0.058 12.7 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 APH PF01636.23 KXG46483.1 - 5.2e-10 39.7 0.0 1.1e-08 35.3 0.0 2.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Abhydrolase_6 PF12697.7 KXG46484.1 - 5.2e-15 56.6 0.6 8.3e-15 56.0 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG46484.1 - 4.8e-11 42.4 0.1 1e-10 41.3 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXG46484.1 - 3e-06 27.1 0.1 4.5e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KXG46484.1 - 2.4e-05 24.3 0.0 3.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KXG46484.1 - 0.0029 17.5 0.1 0.043 13.6 0.0 2.5 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KXG46484.1 - 0.0095 15.4 0.1 0.06 12.8 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 KXG46484.1 - 0.014 14.0 0.1 0.04 12.6 0.1 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2752 PF10825.8 KXG46485.1 - 0.095 12.8 4.1 0.16 12.1 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) DSBA PF01323.20 KXG46485.1 - 0.15 11.8 0.3 3.6 7.3 0.0 2.2 2 0 0 2 2 2 0 DSBA-like thioredoxin domain DUF5094 PF17015.5 KXG46485.1 - 1.1 9.4 3.4 2.1 8.4 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) F-box-like PF12937.7 KXG46486.1 - 2e-06 27.6 2.6 1.7e-05 24.6 2.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXG46486.1 - 0.052 13.4 0.4 0.052 13.4 0.4 2.2 2 0 0 2 2 2 0 F-box domain CRF1 PF10380.9 KXG46487.1 - 0.031 14.6 0.1 0.031 14.6 0.1 3.2 4 0 0 4 4 4 0 Transcription factor CRF1 S36_mt PF10937.8 KXG46487.1 - 7.6 8.2 8.6 28 6.3 2.9 2.7 2 0 0 2 2 2 0 Ribosomal protein S36, mitochondrial SLX9 PF15341.6 KXG46487.1 - 8.6 6.8 10.5 0.82 10.1 4.7 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 RhoGEF67_u1 PF16615.5 KXG46489.1 - 0.067 13.7 0.1 0.095 13.2 0.1 1.3 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 CFEM PF05730.11 KXG46490.1 - 0.00042 20.3 6.3 0.00042 20.3 6.3 4.3 6 0 0 6 6 6 1 CFEM domain Tme5_EGF_like PF09064.10 KXG46490.1 - 0.28 11.1 2.5 1.8 8.5 2.5 2.4 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like Epimerase PF01370.21 KXG46491.1 - 7.7e-44 150.0 0.1 9.1e-44 149.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG46491.1 - 1.1e-17 64.4 0.0 1.7e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXG46491.1 - 1.2e-16 60.6 0.1 1.4e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXG46491.1 - 1.8e-13 50.2 0.0 4.2e-13 49.1 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXG46491.1 - 2.5e-05 23.6 0.1 0.0001 21.6 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KXG46491.1 - 0.00013 21.3 0.1 0.036 13.2 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KXG46491.1 - 0.0037 17.2 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Raptor_N PF14538.6 KXG46491.1 - 0.14 12.1 0.0 9.2 6.2 0.0 2.5 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain KR PF08659.10 KXG46491.1 - 0.15 12.0 0.3 0.86 9.5 0.3 2.1 1 1 0 1 1 1 0 KR domain Pkinase PF00069.25 KXG46492.1 - 1.3e-10 41.1 0.0 3.7e-10 39.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG46492.1 - 1.4e-06 27.8 0.0 2.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG46492.1 - 0.16 11.2 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Sds3 PF08598.11 KXG46495.1 - 6.2e-43 147.3 1.4 9.6e-42 143.4 1.4 2.1 1 1 0 1 1 1 1 Sds3-like Hemerythrin PF01814.23 KXG46496.1 - 1.3e-13 51.7 6.8 1.9e-10 41.4 0.8 1.5 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain Myb_DNA-binding PF00249.31 KXG46497.1 - 0.063 13.5 2.3 0.063 13.5 2.3 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Dec-1 PF04624.14 KXG46497.1 - 5.2 7.0 8.9 7.2 6.6 2.3 2.7 2 0 0 2 2 2 0 Dec-1 repeat Ish1 PF10281.9 KXG46499.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Pkinase PF00069.25 KXG46500.1 - 3e-22 79.3 0.0 1.1e-12 47.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG46500.1 - 1.3e-06 27.9 0.0 4.2e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Peptidase_M20 PF01546.28 KXG46501.1 - 1.6e-18 67.2 0.0 2.9e-18 66.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXG46501.1 - 2.3e-14 53.2 0.1 4.8e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain FAD_binding_4 PF01565.23 KXG46502.1 - 6e-23 81.1 0.8 1.2e-22 80.1 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain Glyoxalase_3 PF13468.6 KXG46503.1 - 4.4e-13 49.7 0.0 6.2e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain PPO1_DWL PF12142.8 KXG46503.1 - 2.5 8.0 3.6 5.1 7.0 0.0 2.5 3 0 0 3 3 3 0 Polyphenol oxidase middle domain Beta-lactamase PF00144.24 KXG46504.1 - 4.3e-36 124.8 0.0 5.9e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KXG46504.1 - 1.3e-12 48.1 0.0 2.3e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Ribonucleas_3_3 PF14622.6 KXG46505.1 - 1.4e-07 31.7 0.0 2.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXG46505.1 - 8.2e-06 26.4 0.0 3.6e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain Profilin PF00235.19 KXG46505.1 - 0.01 16.1 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 0 Profilin Arylesterase PF01731.20 KXG46505.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Arylesterase Cyt-b5 PF00173.28 KXG46506.1 - 4e-18 65.3 0.0 7.4e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 KXG46506.1 - 1.9e-16 60.7 17.6 1.9e-16 60.7 17.6 1.9 2 1 0 2 2 2 1 Fatty acid desaturase YndJ PF14158.6 KXG46506.1 - 0.025 13.9 2.5 0.042 13.2 2.5 1.3 1 0 0 1 1 1 0 YndJ-like protein Tad PF13400.6 KXG46506.1 - 4.2 7.7 7.9 20 5.6 1.0 3.8 4 0 0 4 4 4 0 Putative Flp pilus-assembly TadE/G-like Mito_carr PF00153.27 KXG46509.1 - 5.5e-58 192.9 2.8 1.5e-18 66.5 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXG46509.1 - 0.023 13.9 0.4 5.5 6.1 0.0 2.6 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Aldose_epim PF01263.20 KXG46510.1 - 5.1e-47 160.6 0.2 6.8e-47 160.2 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase ACOX PF01756.19 KXG46511.1 - 3e-41 140.9 0.6 8.2e-41 139.5 0.3 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KXG46511.1 - 2.2e-25 89.6 1.4 4.4e-25 88.6 1.4 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KXG46511.1 - 3.5e-08 33.5 0.0 1.1e-07 32.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KXG46511.1 - 0.018 15.2 0.4 0.093 12.9 0.4 2.1 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain DUF2019 PF09450.10 KXG46511.1 - 0.078 12.9 0.0 0.23 11.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2019) Amino_oxidase PF01593.24 KXG46512.1 - 3.9e-52 178.1 0.0 5e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXG46512.1 - 2.8e-14 53.1 0.2 5.5e-14 52.1 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXG46512.1 - 4.1e-09 36.5 2.0 3.3e-08 33.5 1.9 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXG46512.1 - 6.6e-08 32.1 0.2 1.2e-07 31.3 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KXG46512.1 - 1.9e-06 27.5 0.0 3.6e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXG46512.1 - 8.9e-06 25.0 0.4 1.4e-05 24.4 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG46512.1 - 1.7e-05 24.2 0.0 5.6e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXG46512.1 - 3.7e-05 22.6 0.0 0.00027 19.8 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KXG46512.1 - 6.1e-05 23.5 0.0 0.00038 21.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXG46512.1 - 0.00019 20.6 0.0 0.00026 20.2 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KXG46512.1 - 0.00019 20.8 0.3 0.00038 19.8 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KXG46512.1 - 0.00071 18.7 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXG46512.1 - 0.0016 17.7 0.0 0.5 9.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG46512.1 - 0.017 15.1 0.1 0.33 10.9 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding AMP-binding PF00501.28 KXG46513.1 - 1.9e-55 188.2 0.0 2.3e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG46513.1 - 8.7e-12 45.9 0.0 2.2e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ECH_1 PF00378.20 KXG46514.1 - 3e-23 82.4 0.0 4e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXG46514.1 - 1.1e-11 44.8 0.0 1.3e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Fungal_trans PF04082.18 KXG46515.1 - 2.2e-16 59.7 0.1 3.7e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG46515.1 - 2.9e-05 24.1 13.1 6.7e-05 22.9 13.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Actin PF00022.19 KXG46516.1 - 1.9e-17 63.0 0.0 1.7e-15 56.5 0.0 2.3 1 1 0 1 1 1 1 Actin XPG_I PF00867.18 KXG46517.1 - 2.7e-24 85.3 0.0 1.2e-23 83.2 0.0 2.2 2 0 0 2 2 2 1 XPG I-region GEN1_C PF18380.1 KXG46517.1 - 6.6e-20 72.0 1.9 1.3e-19 71.0 0.0 2.4 2 0 0 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 KXG46517.1 - 1.6e-06 28.5 0.0 3.9e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain Gag_p12 PF01141.18 KXG46517.1 - 0.02 15.2 1.3 0.02 15.2 1.3 2.1 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 Glyco_transf_54 PF04666.13 KXG46518.1 - 2.4e-08 33.2 0.2 5.5e-06 25.5 0.2 3.0 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glyco_transf_25 PF01755.17 KXG46518.1 - 0.0039 17.1 0.0 0.0077 16.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) UPF0449 PF15136.6 KXG46520.1 - 0.041 14.4 0.4 0.25 11.8 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 p450 PF00067.22 KXG46521.1 - 1.4e-55 188.9 0.0 2.1e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 KXG46522.1 - 1.7e-67 227.7 0.0 3.7e-67 226.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KXG46522.1 - 3.9e-56 190.5 0.0 6.3e-56 189.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXG46522.1 - 2.8e-54 184.8 0.1 4.8e-54 184.0 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KXG46522.1 - 5.2e-52 176.4 0.2 1.3e-51 175.1 0.0 1.8 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 KXG46522.1 - 1.3e-37 128.4 1.2 5.3e-37 126.4 1.2 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXG46522.1 - 2.6e-18 66.5 0.0 6.3e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KXG46522.1 - 2e-16 61.2 0.1 5.1e-15 56.7 0.0 3.0 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXG46522.1 - 4.3e-11 42.9 1.3 1.3e-10 41.4 0.1 2.5 3 0 0 3 3 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXG46522.1 - 9.3e-08 31.8 0.1 1e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.12 KXG46522.1 - 0.00014 21.7 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KXG46522.1 - 0.00016 21.9 0.1 0.00048 20.4 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KXG46522.1 - 0.0073 15.7 0.1 0.018 14.4 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KXG46522.1 - 0.044 13.6 0.7 0.13 12.1 0.7 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short PF00106.25 KXG46523.1 - 7.6e-39 133.2 0.3 9.3e-39 132.9 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG46523.1 - 5.7e-31 107.9 0.0 6.9e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG46523.1 - 6e-05 23.0 1.0 0.00018 21.5 1.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXG46523.1 - 0.0081 15.7 0.1 0.016 14.7 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXG46523.1 - 0.15 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain DUF3237 PF11578.8 KXG46524.1 - 1.9e-30 105.7 0.0 3.6e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) FMO-like PF00743.19 KXG46524.1 - 6.5e-15 54.5 0.1 8.2e-13 47.6 0.1 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXG46524.1 - 2e-10 40.8 0.0 6.6e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG46524.1 - 1.6e-06 27.6 0.0 0.00049 19.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG46524.1 - 5e-06 26.0 0.0 9.4e-05 21.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG46524.1 - 0.00015 21.1 0.0 0.0063 15.7 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KXG46524.1 - 0.0059 15.9 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KXG46524.1 - 0.013 15.2 0.4 1.9 8.0 0.1 2.9 2 1 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXG46524.1 - 0.05 13.6 0.1 14 5.6 0.0 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KXG46524.1 - 0.31 9.7 0.6 0.66 8.6 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_4 PF01565.23 KXG46525.1 - 3.2e-24 85.3 0.4 5.2e-24 84.6 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG46525.1 - 9.7e-06 25.6 0.0 2.6e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_5 PF00941.21 KXG46525.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase Cupin_2 PF07883.11 KXG46526.1 - 3.5e-08 33.0 0.1 2.1e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Ppnp PF06865.11 KXG46526.1 - 0.011 16.1 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Pyrimidine/purine nucleoside phosphorylase Cupin_3 PF05899.12 KXG46526.1 - 0.044 13.5 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) adh_short_C2 PF13561.6 KXG46527.1 - 4.5e-61 206.4 3.3 1.5e-60 204.7 3.3 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG46527.1 - 2.4e-46 157.7 2.0 4.9e-46 156.7 2.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG46527.1 - 5.6e-12 45.9 0.8 1e-11 45.1 0.4 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXG46527.1 - 0.001 18.6 0.1 0.0014 18.1 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXG46527.1 - 0.02 14.0 0.2 0.025 13.7 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Enoyl_reductase PF12241.8 KXG46527.1 - 0.055 12.8 0.1 0.098 12.0 0.1 1.4 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region NAD_binding_2 PF03446.15 KXG46527.1 - 0.075 13.2 0.2 0.19 11.9 0.1 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Fungal_trans_2 PF11951.8 KXG46529.1 - 2.5e-10 39.7 0.1 3.6e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KXG46530.1 - 9e-11 41.6 0.0 1.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG46530.1 - 2.2e-05 24.5 0.0 3.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KXG46530.1 - 0.0012 18.4 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MACPF PF01823.19 KXG46532.1 - 9.4e-05 22.6 0.0 0.0002 21.5 0.0 1.5 1 0 0 1 1 1 1 MAC/Perforin domain MlaC PF05494.12 KXG46532.1 - 0.053 13.3 0.7 0.35 10.6 0.1 2.5 3 0 0 3 3 3 0 MlaC protein Jnk-SapK_ap_N PF09744.9 KXG46533.1 - 0.074 13.3 0.4 0.074 13.3 0.4 3.0 2 2 1 3 3 3 0 JNK_SAPK-associated protein-1 CTP_transf_1 PF01148.20 KXG46534.1 - 6.7e-05 22.8 1.9 9.5e-05 22.3 1.9 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family TPPK_C PF12555.8 KXG46534.1 - 3.6 7.7 7.7 10 6.2 0.1 3.3 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal DEAD PF00270.29 KXG46535.1 - 1.9e-37 128.7 0.0 4.4e-37 127.5 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG46535.1 - 8.2e-23 80.9 0.0 2.4e-22 79.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXG46535.1 - 2e-22 79.2 0.1 3.8e-22 78.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXG46535.1 - 0.0039 17.2 0.5 0.019 15.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXG46535.1 - 0.062 12.5 0.0 0.062 12.5 0.0 2.0 2 1 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 KXG46535.1 - 0.14 12.4 0.1 1.8 8.8 0.1 2.6 1 1 0 1 1 1 0 AAA domain Ribosomal_L20 PF00453.18 KXG46535.1 - 1.4 9.0 9.4 3.2 7.9 9.4 1.5 1 0 0 1 1 1 0 Ribosomal protein L20 MFS_1 PF07690.16 KXG46536.1 - 1.3e-33 116.4 28.5 1.3e-33 116.4 28.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily GFO_IDH_MocA PF01408.22 KXG46537.1 - 2.3e-17 63.9 0.0 3.9e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXG46537.1 - 9.2e-16 57.9 0.2 2.1e-15 56.7 0.2 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain APH PF01636.23 KXG46538.1 - 1.5e-10 41.4 0.0 3.8e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KXG46538.1 - 0.014 14.7 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 0 Fructosamine kinase EcKinase PF02958.20 KXG46538.1 - 0.046 13.0 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RNA_pol_Rpb4 PF03874.16 KXG46539.1 - 8.9e-06 26.0 0.0 0.21 11.9 0.5 2.5 2 1 0 2 2 2 2 RNA polymerase Rpb4 Nop PF01798.18 KXG46540.1 - 3.5e-83 278.6 0.0 8.4e-83 277.3 0.0 1.7 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KXG46540.1 - 6.8e-23 80.8 2.7 6.8e-23 80.8 2.7 2.9 2 1 0 2 2 2 1 NOP5NT (NUC127) domain DUF5531 PF17671.1 KXG46540.1 - 4.2 7.2 6.2 7.7 6.4 6.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5531) vATP-synt_AC39 PF01992.16 KXG46541.1 - 3.8e-105 352.1 0.0 4.2e-105 351.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit HAD_2 PF13419.6 KXG46542.1 - 4.9e-25 88.6 0.0 5.9e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXG46542.1 - 2.2e-12 47.7 0.7 2.4e-11 44.3 0.7 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXG46542.1 - 8.1e-10 39.4 0.0 1.1e-09 39.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXG46542.1 - 8.6e-09 35.3 0.0 2.3e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KXG46542.1 - 1.2e-05 25.3 0.1 0.0011 19.0 0.0 2.4 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 KXG46542.1 - 0.091 12.6 0.1 3.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Acid Phosphatase Hydrolase_3 PF08282.12 KXG46542.1 - 0.15 11.8 0.0 0.78 9.4 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Pribosyl_synth PF14572.6 KXG46543.1 - 1e-38 133.2 2.2 3.1e-33 115.3 0.7 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KXG46543.1 - 5.4e-33 113.4 0.0 1.2e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KXG46543.1 - 6.1e-14 51.8 0.2 1.1e-13 51.0 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXG46543.1 - 0.0069 15.8 0.3 0.011 15.1 0.3 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ubiquitin PF00240.23 KXG46544.1 - 0.0016 18.1 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 KXG46544.1 - 0.0023 18.6 0.0 0.0037 17.9 0.0 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD DUF4661 PF15576.6 KXG46544.1 - 0.33 10.8 4.6 0.22 11.4 3.2 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4661) PIG-H PF10181.9 KXG46545.1 - 1.2e-25 89.2 0.5 2e-25 88.4 0.5 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DUF5453 PF17534.2 KXG46545.1 - 0.13 12.2 0.4 1.1 9.2 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5453) Peptidase_C8 PF03569.13 KXG46545.1 - 0.16 11.5 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C8 PseudoU_synth_1 PF01416.20 KXG46546.1 - 1.6e-34 118.6 0.0 1e-32 112.8 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase Ras PF00071.22 KXG46547.1 - 1.9e-17 63.4 0.0 1.4e-16 60.5 0.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXG46547.1 - 0.001 19.3 0.0 0.0033 17.6 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KXG46547.1 - 0.0011 18.2 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_16 PF13191.6 KXG46547.1 - 0.0052 17.2 0.1 0.0094 16.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KXG46547.1 - 0.0086 16.0 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Arf PF00025.21 KXG46547.1 - 0.027 13.9 0.0 0.18 11.3 0.0 2.0 1 1 0 1 1 1 0 ADP-ribosylation factor family ABC_tran PF00005.27 KXG46547.1 - 0.028 14.9 0.0 0.035 14.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KXG46547.1 - 0.036 13.8 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXG46547.1 - 0.052 13.8 0.0 0.084 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXG46547.1 - 0.054 13.3 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KXG46547.1 - 0.069 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXG46547.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ribosomal_S2 PF00318.20 KXG46548.1 - 3.1e-25 88.7 0.1 4e-15 55.6 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KXG46548.1 - 5.1e-08 34.2 14.9 1.1e-07 33.1 14.9 1.6 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S15 PF00312.22 KXG46549.1 - 4.7e-26 90.8 1.9 5.8e-26 90.5 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein S15 COesterase PF00135.28 KXG46551.1 - 2.3e-37 129.1 0.0 3.5e-36 125.1 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG46551.1 - 0.011 15.6 0.1 2.1 8.1 0.0 2.6 3 0 0 3 3 3 0 alpha/beta hydrolase fold APH PF01636.23 KXG46553.1 - 2.4e-20 73.5 0.0 6.7e-20 72.0 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KXG46553.1 - 0.0034 16.3 0.3 0.57 9.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Kdo PF06293.14 KXG46553.1 - 0.0047 16.3 0.4 2.9 7.2 0.0 2.6 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Synaptonemal_3 PF15191.6 KXG46553.1 - 0.05 13.4 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 Synaptonemal complex central element protein 3 EcKinase PF02958.20 KXG46553.1 - 0.066 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Fructosamin_kin PF03881.14 KXG46553.1 - 0.074 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Lectin_C_term PF18022.1 KXG46553.1 - 0.083 13.4 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin C-terminal domain Ank_2 PF12796.7 KXG46554.1 - 1.9e-71 236.7 1.7 1.4e-13 51.2 0.4 8.2 4 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG46554.1 - 1.9e-56 181.4 1.4 0.002 18.5 0.0 15.1 15 1 1 16 16 16 12 Ankyrin repeat Ank_4 PF13637.6 KXG46554.1 - 3.1e-54 180.7 3.3 1.2e-06 28.9 0.0 11.6 7 3 4 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG46554.1 - 1.5e-45 152.7 4.8 1.2e-09 38.2 0.2 9.8 6 2 3 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 KXG46554.1 - 2.6e-37 125.7 9.6 1.9e-06 28.1 0.6 14.0 13 1 0 13 13 13 10 Ankyrin repeat CorA PF01544.18 KXG46554.1 - 1.1e-17 64.3 0.2 2.1e-17 63.4 0.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ADH_N PF08240.12 KXG46554.1 - 0.00033 20.5 0.2 0.00087 19.2 0.2 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain HSCB_C PF07743.13 KXG46554.1 - 0.18 12.3 1.3 0.71 10.4 1.3 2.0 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain COG5 PF10392.9 KXG46556.1 - 0.015 15.5 0.0 0.045 13.9 0.0 1.9 1 0 0 1 1 1 0 Golgi transport complex subunit 5 SKG6 PF08693.10 KXG46557.1 - 1.2e-05 24.6 0.8 2.6e-05 23.5 0.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 KXG46557.1 - 0.014 15.5 4.9 0.027 14.6 4.9 1.4 1 0 0 1 1 1 0 Podoplanin Mid2 PF04478.12 KXG46557.1 - 0.27 11.1 2.6 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Gram_pos_anchor PF00746.21 KXG46557.1 - 0.35 10.9 2.9 0.67 9.9 0.8 2.3 1 1 1 2 2 2 0 LPXTG cell wall anchor motif Band_7 PF01145.25 KXG46558.1 - 3.2e-27 95.7 2.1 5.1e-27 95.0 2.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KXG46558.1 - 0.024 14.3 0.3 0.038 13.7 0.3 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Bac_luciferase PF00296.20 KXG46559.1 - 1.6e-58 198.6 0.9 2.3e-58 198.1 0.9 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase FMO-like PF00743.19 KXG46560.1 - 2.1e-17 62.7 0.1 2.5e-14 52.6 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXG46560.1 - 2.5e-11 43.6 0.0 6.7e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG46560.1 - 1.4e-09 37.7 0.0 1.5e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG46560.1 - 1.9e-05 24.1 0.7 7.6e-05 22.1 0.2 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG46560.1 - 0.00011 21.5 0.0 0.00043 19.5 0.0 1.7 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXG46560.1 - 0.022 14.3 1.3 10 5.6 0.3 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXG46560.1 - 0.03 14.3 0.7 0.24 11.4 0.0 2.7 3 1 1 4 4 4 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KXG46560.1 - 0.04 13.3 0.0 0.36 10.2 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 KXG46560.1 - 0.066 12.4 0.1 0.17 11.1 0.1 1.6 1 0 0 1 1 1 0 Thi4 family DnaB_2 PF07261.11 KXG46560.1 - 0.067 12.9 0.5 1.4 8.7 0.1 2.4 2 0 0 2 2 2 0 Replication initiation and membrane attachment DUF736 PF05284.12 KXG46560.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF736) Methyltransf_2 PF00891.18 KXG46561.1 - 4.2e-22 78.5 0.0 6.9e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Acetyltransf_1 PF00583.25 KXG46563.1 - 1.9e-08 34.5 0.0 2.7e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXG46563.1 - 2.3e-06 27.6 0.0 3.3e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXG46563.1 - 1.6e-05 25.2 0.0 2.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG46563.1 - 0.041 13.8 0.0 0.12 12.4 0.0 1.8 1 1 1 2 2 2 0 FR47-like protein Acetyltransf_CG PF14542.6 KXG46563.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase adh_short PF00106.25 KXG46564.1 - 4.3e-12 45.9 0.1 1.5e-11 44.2 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG46564.1 - 5.3e-10 39.2 0.0 6.2e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG46564.1 - 0.046 13.6 0.0 0.13 12.2 0.0 1.8 1 1 0 1 1 1 0 KR domain CENP-L PF13092.6 KXG46565.1 - 1.2e-47 162.1 0.4 2.5e-47 161.1 0.4 1.5 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 F-box PF00646.33 KXG46565.1 - 2.8e-05 23.9 0.4 0.00015 21.6 0.1 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXG46565.1 - 6.1e-05 22.8 0.2 0.00016 21.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like Sulfate_transp PF00916.20 KXG46566.1 - 2.9e-65 220.5 19.9 4.8e-65 219.8 19.9 1.4 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXG46566.1 - 2.7e-15 56.0 0.0 4.5e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KXG46566.1 - 0.00012 22.3 0.0 0.00048 20.4 0.0 2.1 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 KXG46566.1 - 0.76 10.2 16.1 0.25 11.8 5.2 2.7 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily EIF_2_alpha PF07541.12 KXG46567.1 - 5.5e-38 129.6 0.0 1e-37 128.7 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KXG46567.1 - 1.8e-07 31.4 0.2 5e-07 30.0 0.2 1.8 1 1 0 1 1 1 1 S1 RNA binding domain PKD_channel PF08016.12 KXG46568.1 - 6.2e-05 21.8 19.1 0.00074 18.3 17.9 2.6 1 1 0 1 1 1 1 Polycystin cation channel E1-E2_ATPase PF00122.20 KXG46569.1 - 6.6e-19 68.1 0.0 4.5e-18 65.4 0.0 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KXG46569.1 - 2.4e-13 50.9 1.4 7.4e-07 29.7 1.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXG46569.1 - 0.00015 21.7 0.0 0.075 13.1 0.0 2.5 2 0 0 2 2 2 2 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXG46569.1 - 0.0037 17.1 0.0 0.041 13.6 0.0 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KXG46569.1 - 0.053 13.0 0.2 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Sortilin-Vps10 PF15902.5 KXG46570.1 - 0.0041 16.0 0.7 0.87 8.3 0.3 2.9 2 1 1 3 3 3 2 Sortilin, neurotensin receptor 3, BNR_2 PF13088.6 KXG46570.1 - 0.0054 16.1 0.4 1.1 8.5 0.0 2.2 1 1 0 2 2 2 2 BNR repeat-like domain BNR PF02012.20 KXG46570.1 - 0.065 13.3 7.3 1.6 9.0 0.2 3.7 3 0 0 3 3 3 0 BNR/Asp-box repeat Glyco_hydro_3_C PF01915.22 KXG46571.1 - 5.9e-41 140.7 0.0 8.6e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXG46571.1 - 1.8e-34 119.5 0.0 2.9e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DUF5346 PF17281.2 KXG46573.1 - 0.027 14.5 0.2 0.059 13.4 0.0 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5346) Fungal_trans PF04082.18 KXG46574.1 - 1.1e-09 37.7 0.1 1.9e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.13 KXG46575.1 - 2.4e-40 138.5 0.0 2.9e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG46575.1 - 7.2e-11 42.3 0.0 9.9e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXG46575.1 - 4.7e-05 23.0 0.1 8.6e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXG46575.1 - 7.3e-05 23.0 0.1 0.00016 21.9 0.1 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 KXG46575.1 - 0.00089 20.0 0.1 0.0015 19.2 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3Beta_HSD PF01073.19 KXG46575.1 - 0.0046 16.0 0.0 0.0065 15.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KXG46575.1 - 0.0052 17.2 0.2 0.015 15.7 0.1 1.9 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KXG46575.1 - 0.067 13.3 0.0 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF3842 PF12953.7 KXG46575.1 - 0.09 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) FMO-like PF00743.19 KXG46576.1 - 4.8e-13 48.4 0.0 1e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXG46576.1 - 5.8e-11 42.5 0.0 1.8e-09 37.7 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG46576.1 - 4.7e-06 26.0 0.0 0.00016 21.0 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG46576.1 - 7.7e-05 22.0 0.0 0.0034 16.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXG46576.1 - 0.00015 21.2 0.0 0.0014 18.0 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG46576.1 - 0.002 18.2 0.0 0.01 15.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KXG46576.1 - 0.0075 15.9 0.0 17 4.9 0.0 3.2 2 1 0 3 3 3 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 KXG46576.1 - 0.17 11.4 0.0 2.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Aldo_ket_red PF00248.21 KXG46577.1 - 3.1e-38 131.6 0.0 5.6e-36 124.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KXG46578.1 - 4.3e-12 45.8 0.0 6.4e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 KXG46579.1 - 3.1e-09 36.8 7.6 6.5e-09 35.8 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kdo PF06293.14 KXG46579.1 - 5.3e-09 35.7 0.0 1.6e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXG46579.1 - 6.1e-07 29.6 0.0 0.018 15.0 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KXG46579.1 - 1.3e-06 28.0 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CoiA PF06054.11 KXG46579.1 - 0.021 14.0 0.0 0.052 12.7 0.0 1.6 1 0 0 1 1 1 0 Competence protein CoiA-like family Pkinase_fungal PF17667.1 KXG46579.1 - 0.035 12.9 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KXG46579.1 - 0.076 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase RNA_pol_Rpb1_1 PF04997.12 KXG46580.1 - 1.3e-84 284.2 0.1 2.1e-84 283.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KXG46580.1 - 3e-79 266.2 0.1 4.6e-79 265.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KXG46580.1 - 3.9e-72 241.9 0.0 1.1e-71 240.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 GTP_EFTU PF00009.27 KXG46580.1 - 6.6e-49 166.1 0.0 1.2e-48 165.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RNA_pol_Rpb1_3 PF04983.18 KXG46580.1 - 3.8e-33 114.6 0.0 4.8e-32 111.1 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KXG46580.1 - 3.7e-27 94.4 0.1 9.1e-27 93.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 LepA_C PF06421.12 KXG46580.1 - 1.9e-26 92.3 0.1 4.3e-26 91.2 0.1 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KXG46580.1 - 2e-18 66.2 0.0 6.2e-18 64.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KXG46580.1 - 0.0019 18.3 0.0 0.0055 16.8 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 KXG46580.1 - 0.0032 17.1 0.0 0.0067 16.0 0.0 1.5 1 0 0 1 1 1 1 Ras family GTP_EFTU_D2 PF03144.25 KXG46580.1 - 0.0045 17.4 0.0 0.013 15.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 KXG46580.1 - 0.06 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RF3_C PF16658.5 KXG46580.1 - 0.077 12.8 0.0 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain HORMA PF02301.18 KXG46581.1 - 1.8e-34 119.2 0.1 2.2e-34 118.9 0.1 1.0 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 KXG46581.1 - 0.023 14.5 0.1 0.048 13.5 0.0 1.6 2 0 0 2 2 2 0 Bacterial HORMA domain 2 RE_EcoO109I PF14511.6 KXG46581.1 - 0.11 12.1 2.0 0.17 11.5 2.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I RasGAP PF00616.19 KXG46581.1 - 0.23 11.2 2.5 0.38 10.4 2.5 1.4 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF218 PF02698.17 KXG46582.1 - 6.3e-05 23.0 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 DUF218 domain zf-CCCH_4 PF18044.1 KXG46585.1 - 1.1e-07 31.4 3.1 1.8e-07 30.8 3.1 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXG46585.1 - 1.8e-07 31.0 6.2 3.3e-07 30.1 6.2 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KXG46585.1 - 5.9e-05 22.9 1.1 9.9e-05 22.2 1.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KXG46585.1 - 0.00054 20.6 0.3 0.0021 18.8 0.3 2.0 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 KXG46585.1 - 0.0055 17.1 2.9 0.0099 16.3 2.9 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KXG46585.1 - 0.01 16.0 0.2 0.022 14.9 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger containing family ELM2 PF01448.24 KXG46585.1 - 0.93 10.3 3.5 30 5.4 0.1 3.3 2 0 0 2 2 2 0 ELM2 domain Sec1 PF00995.23 KXG46587.1 - 6.4e-129 431.8 0.0 7.3e-129 431.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family FYVE PF01363.21 KXG46589.1 - 5.3e-22 77.7 26.7 2.9e-17 62.5 5.3 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KXG46589.1 - 6.6e-18 64.2 1.7 1.4e-17 63.1 0.4 2.3 2 0 0 2 2 2 1 Rabenosyn Rab binding domain zf-Di19 PF05605.12 KXG46589.1 - 0.001 19.3 6.5 0.18 12.1 0.1 2.8 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 KXG46589.1 - 0.0019 18.3 6.2 0.0019 18.3 6.2 3.8 3 1 1 4 4 4 1 AN1-like Zinc finger TMF_TATA_bd PF12325.8 KXG46589.1 - 0.015 15.5 0.4 0.015 15.5 0.4 2.8 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding YqaH PF17448.2 KXG46589.1 - 0.027 14.8 0.1 0.072 13.4 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized YqaH-like UBZ_FAAP20 PF15750.5 KXG46589.1 - 0.23 11.4 3.9 8 6.5 0.4 2.9 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-WRNIP1_ubi PF18279.1 KXG46589.1 - 0.68 10.7 3.1 27 5.7 0.1 2.9 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-NADH-PPase PF09297.11 KXG46589.1 - 3.5 7.4 11.1 2.1 8.1 0.3 3.5 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain GLTP PF08718.11 KXG46591.1 - 3.8e-46 157.1 0.0 5.2e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Cir_N PF10197.9 KXG46591.1 - 0.051 13.8 0.5 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR PH_4 PF15404.6 KXG46592.1 - 1.5e-53 181.4 0.4 1.5e-53 181.4 0.4 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.6 KXG46592.1 - 1.1e-23 82.6 0.7 2.8e-23 81.3 0.7 1.8 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.29 KXG46592.1 - 1.8e-10 41.2 0.0 0.0047 17.4 0.0 5.3 4 1 0 4 4 4 2 PH domain PH_6 PF15406.6 KXG46592.1 - 0.039 14.2 0.1 4.6 7.6 0.0 3.0 2 0 0 2 2 2 0 Pleckstrin homology domain DUF1654 PF07867.11 KXG46592.1 - 0.076 12.8 0.2 0.26 11.0 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Peptidase_S24 PF00717.23 KXG46593.1 - 1.2e-08 34.8 0.1 1.1e-07 31.7 0.1 2.2 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KXG46593.1 - 0.013 15.3 0.0 5.7 6.7 0.0 2.5 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 Macro PF01661.21 KXG46594.1 - 4.5e-41 139.6 0.1 6e-41 139.2 0.1 1.2 1 0 0 1 1 1 1 Macro domain GATA PF00320.27 KXG46595.1 - 3.3e-15 55.4 5.3 5.8e-15 54.6 5.3 1.4 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 KXG46595.1 - 0.39 11.0 1.6 0.86 9.9 1.6 1.5 1 0 0 1 1 1 0 zinc-ribbon DEC-1_N PF04625.13 KXG46595.1 - 6.5 5.7 9.6 12 4.8 9.6 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region COesterase PF00135.28 KXG46596.1 - 7e-98 328.7 0.0 8.8e-98 328.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG46596.1 - 2.1e-05 24.5 0.5 0.004 17.0 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXG46596.1 - 0.0039 16.7 0.1 0.0067 15.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1749 PF08538.10 KXG46596.1 - 0.025 13.6 0.1 0.063 12.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) GCS PF03074.16 KXG46598.1 - 3.8e-176 585.8 0.0 4.8e-176 585.5 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF1560 PF07597.11 KXG46598.1 - 0.11 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) Cytochrom_B561 PF03188.16 KXG46598.1 - 0.19 11.9 0.0 6.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 NDUF_B7 PF05676.13 KXG46599.1 - 1.8e-29 101.3 7.2 2.2e-29 101.0 7.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KXG46599.1 - 0.031 14.3 3.9 0.042 13.9 3.9 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ank_2 PF12796.7 KXG46600.1 - 2.1e-10 41.0 1.5 0.00093 19.7 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG46600.1 - 4.9e-09 36.5 0.4 0.00014 22.4 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG46600.1 - 4.1e-08 33.3 0.5 4.1e-05 23.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG46600.1 - 1e-07 31.6 0.7 0.002 18.4 0.1 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KXG46600.1 - 3.8e-07 30.3 1.6 1.3e-05 25.4 0.1 3.0 3 0 0 3 3 2 1 Ankyrin repeat KilA-N PF04383.13 KXG46600.1 - 2.8e-05 23.9 0.5 0.00021 21.1 0.0 2.6 3 0 0 3 3 3 1 KilA-N domain RskA PF10099.9 KXG46600.1 - 0.00076 19.8 2.6 0.003 17.9 2.6 2.0 1 0 0 1 1 1 1 Anti-sigma-K factor rskA HALZ PF02183.18 KXG46600.1 - 0.046 13.9 4.4 4.4 7.6 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper TRCF PF03461.15 KXG46600.1 - 0.05 14.0 1.2 0.43 11.0 1.1 2.3 2 0 0 2 2 2 0 TRCF domain TrmB PF01978.19 KXG46600.1 - 0.055 13.3 0.1 7.8 6.5 0.0 3.3 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB Vir_act_alpha_C PF10400.9 KXG46600.1 - 4.7 8.0 6.2 5.1 7.8 4.5 2.0 2 1 0 2 2 1 0 Virulence activator alpha C-term adh_short PF00106.25 KXG46601.1 - 4.2e-06 26.4 0.0 7.5e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG46601.1 - 5e-06 26.2 0.0 7.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 KXG46602.1 - 3.9e-22 78.7 0.0 5.6e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KXG46602.1 - 6.4e-07 29.1 0.0 1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXG46602.1 - 0.061 13.7 0.2 0.16 12.3 0.2 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site ThrE PF06738.12 KXG46604.1 - 5.7e-75 251.8 16.5 1.1e-68 231.2 4.1 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KXG46604.1 - 3.8e-10 40.0 11.1 3.8e-10 40.0 11.1 3.0 3 1 0 3 3 3 2 Threonine/Serine exporter, ThrE NMN_transporter PF04973.12 KXG46604.1 - 0.4 10.6 7.8 21 5.0 7.8 2.4 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter APH PF01636.23 KXG46605.1 - 1.4e-12 48.0 0.0 4.1e-12 46.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KXG46605.1 - 0.07 12.0 0.0 2.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) IlvN PF07991.12 KXG46606.1 - 8.6e-45 152.3 0.0 1.3e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KXG46606.1 - 2.9e-39 134.7 0.0 4.5e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 KXG46606.1 - 0.06 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PALP PF00291.25 KXG46607.1 - 1e-70 238.5 0.4 1.4e-70 238.1 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXG46607.1 - 0.035 13.4 0.2 0.088 12.1 0.1 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Rad51 PF08423.11 KXG46608.1 - 5.2e-07 29.2 0.0 2.1e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Rad51 TAF8_C PF10406.9 KXG46609.1 - 3.3e-20 72.4 0.0 7.4e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KXG46609.1 - 3.1e-08 33.5 0.0 5.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated PAP2 PF01569.21 KXG46609.1 - 0.19 11.5 0.1 0.28 10.9 0.1 1.2 1 0 0 1 1 1 0 PAP2 superfamily Chitin_synth_1 PF01644.17 KXG46610.1 - 7.4e-69 230.9 0.0 1.1e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase UQ_con PF00179.26 KXG46610.1 - 1.4e-36 125.2 0.0 2.3e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Chitin_synth_1N PF08407.11 KXG46610.1 - 2.5e-28 97.8 0.0 4.9e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KXG46610.1 - 6.4e-24 84.5 0.0 6.1e-20 71.3 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXG46610.1 - 2.7e-10 40.5 1.4 8.1e-10 38.9 0.1 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Opy2 PF09463.10 KXG46611.1 - 1.4e-08 34.9 22.9 2.7e-08 34.0 22.9 1.5 1 0 0 1 1 1 1 Opy2 protein CcmD PF04995.14 KXG46611.1 - 0.14 12.3 0.4 0.26 11.4 0.4 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) SKG6 PF08693.10 KXG46611.1 - 0.15 11.5 2.5 0.35 10.3 2.5 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 KXG46611.1 - 0.2 11.6 1.3 0.37 10.7 1.3 1.3 1 0 0 1 1 1 0 Syndecan domain UEV PF05743.13 KXG46612.1 - 2.5e-38 130.6 0.1 5e-38 129.7 0.1 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KXG46612.1 - 4.2e-20 71.4 0.0 1e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 KXG46612.1 - 0.15 11.7 0.1 0.15 11.7 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme STE2 PF02116.15 KXG46613.1 - 1e-101 340.0 25.8 1.2e-101 339.7 25.8 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR BAR PF03114.18 KXG46614.1 - 5.1e-64 216.2 8.9 6.5e-64 215.8 8.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KXG46614.1 - 9.1e-14 50.8 0.0 1.8e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXG46614.1 - 2.2e-11 43.4 0.0 3.7e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXG46614.1 - 8.4e-09 35.0 0.1 2.4e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain CT_C_D PF02682.16 KXG46614.1 - 0.066 12.9 0.4 0.12 12.1 0.4 1.4 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D Zn_dep_PLPC PF00882.18 KXG46614.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Zinc dependent phospholipase C TMPIT PF07851.13 KXG46614.1 - 0.26 10.5 5.9 1.2 8.4 0.0 2.2 1 1 1 2 2 2 0 TMPIT-like protein YlqD PF11068.8 KXG46614.1 - 0.67 10.3 5.1 0.69 10.3 0.0 2.6 3 0 0 3 3 3 0 YlqD protein BRE1 PF08647.11 KXG46614.1 - 5.5 7.1 12.7 3.2 7.9 0.2 2.7 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Aminotran_5 PF00266.19 KXG46615.1 - 2e-92 310.0 0.0 2.4e-92 309.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXG46615.1 - 0.00011 21.7 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KXG46615.1 - 0.00038 19.9 0.0 0.0019 17.6 0.0 2.0 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family COesterase PF00135.28 KXG46616.1 - 2.1e-68 231.5 0.0 1.6e-54 185.7 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG46616.1 - 2.2e-07 30.9 0.4 1.4e-06 28.4 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KXG46616.1 - 0.0042 16.9 0.1 0.055 13.3 0.1 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 KXG46616.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase IDO PF01231.18 KXG46617.1 - 1.7e-163 544.4 0.0 2e-163 544.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase CsbD PF05532.12 KXG46618.1 - 8.9e-17 60.7 20.7 4.2e-11 42.6 4.8 3.3 3 0 0 3 3 3 2 CsbD-like DUF1206 PF06724.11 KXG46619.1 - 0.59 10.2 8.5 4.7 7.4 6.5 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) FSA_C PF10479.9 KXG46619.1 - 1.9 6.5 7.1 2.2 6.3 7.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Antimicrobial15 PF08110.12 KXG46620.1 - 1 9.7 3.8 17 5.8 0.3 2.7 2 1 0 2 2 2 0 Ocellatin family DUF2236 PF09995.9 KXG46621.1 - 1.9e-39 136.2 2.0 2.6e-39 135.8 2.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) MDMPI_C PF07398.11 KXG46621.1 - 0.038 14.8 1.0 0.075 13.9 0.1 2.0 2 0 0 2 2 2 0 MDMPI C-terminal domain DUF3712 PF12505.8 KXG46622.1 - 4.8e-27 94.7 1.3 4.8e-27 94.7 1.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) F-box_4 PF15966.5 KXG46623.1 - 0.002 18.0 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 F-box F-box PF00646.33 KXG46623.1 - 0.043 13.7 0.4 0.53 10.2 0.0 2.4 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KXG46623.1 - 0.046 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 F-box-like Peptidase_C14 PF00656.22 KXG46624.1 - 1.8e-48 165.6 0.0 2.3e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Sel1 PF08238.12 KXG46624.1 - 0.17 12.6 0.0 3.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Sel1 repeat Sugar_tr PF00083.24 KXG46626.1 - 7e-97 325.1 20.8 8e-97 324.9 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG46626.1 - 6.6e-19 68.0 48.7 2.1e-17 63.1 24.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nitrate_red_gam PF02665.14 KXG46626.1 - 3.2 7.2 9.1 0.48 9.9 3.7 2.3 2 1 0 2 2 2 0 Nitrate reductase gamma subunit Methyltransf_16 PF10294.9 KXG46628.1 - 3.4e-16 59.4 0.0 5.9e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KXG46628.1 - 0.00028 20.8 0.0 0.00042 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXG46628.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) KTI12 PF08433.10 KXG46629.1 - 2.7e-66 223.8 0.0 4.3e-66 223.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KXG46629.1 - 0.0078 16.4 1.3 0.012 15.8 0.2 1.8 2 0 0 2 2 2 1 AAA domain zf-C2H2 PF00096.26 KXG46630.1 - 0.047 14.1 0.5 4.4 7.9 0.0 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type Palm_thioest PF02089.15 KXG46632.1 - 5.6e-83 278.5 0.0 7e-83 278.2 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 KXG46632.1 - 0.053 12.8 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Med31 PF05669.12 KXG46634.1 - 1.2e-31 108.5 0.0 1.5e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 SOH1 Pal1 PF08316.11 KXG46635.1 - 1.2e-46 158.9 1.1 6.8e-46 156.5 1.1 2.3 1 1 0 1 1 1 1 Pal1 cell morphology protein MCM PF00493.23 KXG46636.1 - 1e-100 335.5 0.0 1.5e-100 334.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXG46636.1 - 2.8e-38 130.6 0.2 5.2e-38 129.7 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KXG46636.1 - 1.1e-30 107.0 40.0 1.1e-30 107.0 40.0 2.0 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KXG46636.1 - 3.6e-23 81.8 2.4 4e-23 81.6 0.6 2.1 2 0 0 2 2 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXG46636.1 - 2.4e-13 50.6 0.1 8.7e-13 48.8 0.1 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXG46636.1 - 1e-08 34.9 0.1 9.8e-07 28.4 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXG46636.1 - 3.2e-05 23.9 0.0 7.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXG46636.1 - 0.0038 17.1 0.0 0.037 13.9 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXG46636.1 - 0.011 15.5 0.2 0.079 12.7 0.2 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Zn_ribbon_2 PF12674.7 KXG46636.1 - 0.03 15.0 0.2 0.084 13.5 0.2 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain AAA_30 PF13604.6 KXG46636.1 - 0.085 12.6 0.3 0.19 11.4 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXG46636.1 - 0.11 12.9 0.3 0.44 11.0 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXG46636.1 - 7 7.0 7.4 1.3 9.3 0.6 3.3 3 1 0 3 3 3 0 AAA ATPase domain zf-UBR PF02207.20 KXG46637.1 - 2.6e-13 49.9 7.5 2.6e-13 49.9 7.5 3.6 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) Pkinase PF00069.25 KXG46638.1 - 3e-64 216.9 0.0 3.7e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG46638.1 - 5.7e-30 104.5 0.0 8.2e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXG46638.1 - 0.0025 16.8 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXG46638.1 - 0.14 12.1 0.0 0.94 9.4 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sugar_tr PF00083.24 KXG46639.1 - 1.7e-86 290.9 14.8 2.2e-86 290.5 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG46639.1 - 4.1e-36 124.6 62.4 2.2e-31 109.1 35.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXG46639.1 - 2.9e-05 23.5 6.4 2.9e-05 23.5 6.4 2.3 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KXG46639.1 - 1.1 7.5 8.7 0.053 11.8 1.6 2.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PS_Dcarbxylase PF02666.15 KXG46640.1 - 2.3e-53 180.7 0.0 3.6e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KXG46640.1 - 2e-37 127.6 0.0 2.5e-17 63.1 0.0 2.4 2 0 0 2 2 2 2 C2 domain PGA2 PF07543.12 KXG46640.1 - 0.013 15.5 2.7 0.16 11.9 0.5 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 EF-hand_1 PF00036.32 KXG46640.1 - 0.029 13.9 0.1 0.097 12.3 0.1 2.0 1 0 0 1 1 1 0 EF hand MIS13 PF08202.11 KXG46641.1 - 8.4e-45 153.3 2.5 8.4e-45 153.3 2.5 2.2 2 1 0 2 2 2 1 Mis12-Mtw1 protein family AT_hook PF02178.19 KXG46641.1 - 0.0016 18.0 8.7 0.33 11.0 1.9 3.6 2 0 0 2 2 2 2 AT hook motif DivIC PF04977.15 KXG46641.1 - 0.054 13.3 2.6 0.12 12.2 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator ABC_tran_CTD PF16326.5 KXG46641.1 - 1.5 9.1 6.3 1.3 9.3 3.1 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain 2OG-FeII_Oxy_2 PF13532.6 KXG46642.1 - 2.1e-27 96.6 0.0 3.8e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 KXG46642.1 - 1.5e-16 61.1 0.0 2.8e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family GST_C_2 PF13410.6 KXG46642.1 - 0.00073 19.5 0.1 0.0018 18.2 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 KXG46642.1 - 0.052 13.4 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Herpes_LP PF03363.13 KXG46642.1 - 0.098 12.4 5.9 4 7.2 2.1 2.5 2 0 0 2 2 2 0 Herpesvirus leader protein Lipase_GDSL_2 PF13472.6 KXG46643.1 - 5e-12 46.6 1.2 5.9e-12 46.3 1.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXG46643.1 - 2e-07 31.2 0.0 2.5e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ECH_1 PF00378.20 KXG46644.1 - 5e-41 140.7 0.0 1.1e-40 139.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXG46644.1 - 4.3e-32 111.9 0.0 2.3e-30 106.3 0.0 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase HSP20 PF00011.21 KXG46645.1 - 6.3e-20 71.2 0.1 7.6e-19 67.8 0.1 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXG46645.1 - 7e-07 28.7 0.0 1.9e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Cu_amine_oxid PF01179.20 KXG46646.1 - 1.5e-162 541.2 0.0 2e-162 540.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Fungal_trans PF04082.18 KXG46646.1 - 1.4e-13 50.5 0.0 2.7e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG46646.1 - 4.1e-05 23.6 8.0 7.3e-05 22.8 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu_amine_oxidN3 PF02728.16 KXG46646.1 - 0.00041 20.7 0.0 0.00095 19.5 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KXG46646.1 - 0.023 14.9 0.1 0.052 13.8 0.1 1.6 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain Glyco_hydro_43 PF04616.14 KXG46647.1 - 2.6e-35 122.1 3.2 3.2e-35 121.8 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_14 PF01373.17 KXG46647.1 - 0.013 14.4 0.5 0.018 14.0 0.5 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 SLAC1 PF03595.17 KXG46648.1 - 1.2e-51 175.9 31.9 1.6e-51 175.5 31.9 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel TPR_12 PF13424.6 KXG46648.1 - 4.9e-31 106.8 12.9 1.6e-11 44.3 0.4 6.0 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KXG46648.1 - 3.2e-16 58.6 15.2 0.0013 18.6 0.1 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 KXG46648.1 - 5.2e-05 23.0 4.1 0.2 11.8 0.3 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXG46648.1 - 7.1e-05 22.7 4.4 1 9.7 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXG46648.1 - 0.00071 19.3 2.4 0.8 9.6 0.2 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat FAM75 PF14650.6 KXG46648.1 - 0.0016 18.1 1.6 0.0034 17.0 1.6 1.4 1 0 0 1 1 1 1 FAM75 family ANAPC3 PF12895.7 KXG46648.1 - 0.008 16.4 2.3 4.6 7.5 0.2 2.9 3 0 0 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KXG46648.1 - 0.011 16.4 3.1 4.6 8.0 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXG46648.1 - 0.012 16.1 9.6 3.5 8.2 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXG46648.1 - 0.027 15.1 6.7 3 8.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXG46648.1 - 0.036 14.2 8.6 0.22 11.7 0.5 3.5 4 0 0 4 4 2 0 Tetratricopeptide repeat Peptidase_M16_C PF05193.21 KXG46648.1 - 0.066 13.2 0.2 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Peptidase M16 inactive domain TPR_14 PF13428.6 KXG46648.1 - 0.18 12.7 6.4 5.1 8.2 0.1 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat MFS_1 PF07690.16 KXG46649.1 - 6.1e-37 127.4 31.1 6.1e-37 127.4 31.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DIOX_N PF14226.6 KXG46649.1 - 1.5e-31 109.6 0.0 2.6e-30 105.6 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG46649.1 - 1.2e-12 48.2 0.0 2.4e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TauD PF02668.16 KXG46649.1 - 0.21 11.4 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family DUF2070 PF09843.9 KXG46649.1 - 6.8 4.9 10.3 13 3.9 10.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MAD PF05557.13 KXG46650.1 - 0.00045 18.7 3.2 0.0007 18.1 3.2 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF3135 PF11333.8 KXG46650.1 - 0.0014 18.9 0.3 1.4 9.2 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3135) HalX PF08663.10 KXG46650.1 - 0.03 14.6 4.3 1.7 9.0 0.2 3.1 1 1 1 3 3 2 0 HalX domain PLU-1 PF08429.11 KXG46650.1 - 0.034 13.3 1.1 0.05 12.8 1.1 1.4 1 0 0 1 1 1 0 PLU-1-like protein DUF1640 PF07798.11 KXG46650.1 - 0.034 14.2 7.0 3.4 7.7 5.2 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) DUF4407 PF14362.6 KXG46650.1 - 0.034 13.5 0.1 0.034 13.5 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Myosin_tail_1 PF01576.19 KXG46650.1 - 0.065 11.0 6.4 0.1 10.4 6.4 1.2 1 0 0 1 1 1 0 Myosin tail Occludin_ELL PF07303.13 KXG46650.1 - 0.067 13.9 6.1 3.4 8.5 0.1 3.0 2 1 1 3 3 3 0 Occludin homology domain PspA_IM30 PF04012.12 KXG46650.1 - 0.1 12.2 4.0 0.23 11.0 4.0 1.5 1 0 0 1 1 1 0 PspA/IM30 family EzrA PF06160.12 KXG46650.1 - 0.14 10.3 7.4 0.74 7.9 3.7 2.7 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA Filament PF00038.21 KXG46650.1 - 0.14 11.7 10.6 0.083 12.5 6.2 2.4 2 1 1 3 3 3 0 Intermediate filament protein DUF1664 PF07889.12 KXG46650.1 - 0.21 11.6 5.9 0.25 11.4 1.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Leu_zip PF15294.6 KXG46650.1 - 0.22 11.0 5.8 0.081 12.4 3.2 1.5 2 0 0 2 2 1 0 Leucine zipper DUF3552 PF12072.8 KXG46650.1 - 0.33 10.3 8.8 2.6 7.4 1.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF3552) DUF4600 PF15372.6 KXG46650.1 - 0.35 11.3 5.3 4.8 7.6 0.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Laminin_II PF06009.12 KXG46650.1 - 0.39 10.7 5.3 0.6 10.1 2.0 2.6 2 1 0 2 2 2 0 Laminin Domain II DUF724 PF05266.14 KXG46650.1 - 0.39 10.5 9.2 0.2 11.5 2.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Lebercilin PF15619.6 KXG46650.1 - 0.46 10.1 9.1 7.1 6.2 9.1 2.3 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Wtap PF17098.5 KXG46650.1 - 0.53 10.2 6.2 1.7 8.6 6.2 1.8 1 0 0 1 1 1 0 WTAP/Mum2p family Golgin_A5 PF09787.9 KXG46650.1 - 0.97 8.8 9.4 0.38 10.2 6.9 1.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 Dynactin_p22 PF07426.11 KXG46650.1 - 1.4 8.8 6.6 0.64 9.9 1.0 2.7 2 2 1 3 3 3 0 Dynactin subunit p22 FlxA PF14282.6 KXG46650.1 - 1.6 8.8 17.2 50 4.0 12.5 3.5 2 1 0 2 2 2 0 FlxA-like protein Phage_GP20 PF06810.11 KXG46650.1 - 1.6 8.5 11.0 0.27 11.0 5.4 2.4 2 1 0 2 2 2 0 Phage minor structural protein GP20 TMPIT PF07851.13 KXG46650.1 - 1.7 7.8 3.5 5.6 6.1 2.1 2.0 2 0 0 2 2 2 0 TMPIT-like protein BST2 PF16716.5 KXG46650.1 - 1.9 9.1 11.8 2.8 8.6 9.8 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Zw10 PF06248.13 KXG46650.1 - 2.2 6.8 6.1 7.3 5.0 4.3 2.2 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 Mod_r PF07200.13 KXG46650.1 - 2.2 8.3 8.6 1.2 9.2 5.8 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Mer2 PF09074.10 KXG46650.1 - 2.4 7.9 9.3 1.3 8.8 4.9 2.5 3 0 0 3 3 2 0 Mer2 Syntaxin_2 PF14523.6 KXG46650.1 - 2.5 8.5 7.6 1e+02 3.3 5.9 3.2 2 1 0 2 2 2 0 Syntaxin-like protein DMPK_coil PF08826.10 KXG46650.1 - 2.6 8.2 10.9 3.6 7.8 1.8 3.1 1 1 1 2 2 2 0 DMPK coiled coil domain like UPF0242 PF06785.11 KXG46650.1 - 3.6 7.6 8.4 2.8 8.0 6.5 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 KXG46650.1 - 4.9 7.7 7.2 24 5.5 3.8 3.3 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 KXG46650.1 - 6.4 7.3 9.9 1.9 9.0 2.7 2.9 2 1 1 3 3 3 0 Protein of unknown function DUF16 COG2 PF06148.11 KXG46650.1 - 8.6 6.5 8.2 37 4.4 3.5 3.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_M35 PF02102.15 KXG46653.1 - 8.4e-34 117.0 5.4 1e-33 116.7 5.4 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KXG46653.1 - 3.7e-24 85.9 1.1 5.3e-24 85.4 1.1 1.2 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KXG46653.1 - 0.0027 17.3 0.2 0.0027 17.3 0.2 1.4 2 0 0 2 2 2 1 Putative peptidase family p450 PF00067.22 KXG46655.1 - 5.2e-46 157.4 0.0 6.9e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_31 PF01055.26 KXG46656.1 - 8.9e-41 140.5 9.1 1.2e-40 140.0 9.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXG46656.1 - 0.027 14.8 0.1 0.11 12.8 0.1 2.2 2 0 0 2 2 2 0 Galactose mutarotase-like Fungal_trans PF04082.18 KXG46657.1 - 8.5e-12 44.7 0.0 1e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAN_1 PF00024.26 KXG46659.1 - 0.00074 19.4 0.2 0.00074 19.4 0.2 1.7 1 1 1 2 2 2 1 PAN domain PAN_1 PF00024.26 KXG46660.1 - 3.7e-11 42.8 20.8 7.7e-07 29.0 4.3 3.2 4 1 1 5 5 5 2 PAN domain PAN_3 PF08277.12 KXG46660.1 - 5.7e-07 29.3 10.6 5.9e-05 22.8 0.5 2.9 3 0 0 3 3 3 2 PAN-like domain PAN_4 PF14295.6 KXG46660.1 - 5.1e-05 23.1 14.8 0.00055 19.8 0.7 3.5 4 0 0 4 4 4 2 PAN domain MANEC PF07502.14 KXG46660.1 - 0.06 13.6 0.6 0.06 13.6 0.6 3.2 3 1 0 3 3 3 0 MANEC domain 2OG-FeII_Oxy_3 PF13640.6 KXG46662.1 - 1.4e-09 38.7 0.0 2.8e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PAN_1 PF00024.26 KXG46663.1 - 2.4e-11 43.4 23.3 0.00013 21.9 5.2 3.6 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.6 KXG46663.1 - 3e-10 39.8 17.2 0.00029 20.7 1.0 4.0 4 0 0 4 4 4 3 PAN domain PAN_3 PF08277.12 KXG46663.1 - 0.00019 21.2 12.0 0.022 14.6 0.4 3.7 3 0 0 3 3 3 3 PAN-like domain MANEC PF07502.14 KXG46663.1 - 0.0023 18.2 19.0 0.2 11.9 0.2 3.7 3 0 0 3 3 3 3 MANEC domain AAA PF00004.29 KXG46664.1 - 1.6e-18 67.4 0.0 2.6e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXG46664.1 - 0.0018 18.6 0.7 2.2 8.6 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 KXG46664.1 - 0.0046 17.3 0.6 0.024 15.0 0.6 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KXG46664.1 - 0.0075 16.8 0.0 0.016 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KXG46664.1 - 0.01 16.2 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXG46664.1 - 0.035 14.1 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXG46664.1 - 0.036 14.2 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DASH_Dad1 PF08649.10 KXG46664.1 - 0.043 14.0 0.7 2.4 8.4 0.1 3.4 4 0 0 4 4 4 0 DASH complex subunit Dad1 AAA_24 PF13479.6 KXG46664.1 - 0.061 13.0 0.1 1.7 8.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXG46664.1 - 0.14 11.5 0.1 0.99 8.7 0.0 2.2 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KXG46664.1 - 0.21 11.9 0.2 0.55 10.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 KXG46665.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 KXG46665.1 - 0.038 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase HSDR_N_2 PF13588.6 KXG46665.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) RIO1 PF01163.22 KXG46665.1 - 0.32 10.6 0.0 0.32 10.6 0.0 1.6 2 0 0 2 2 2 0 RIO1 family DUF3723 PF12520.8 KXG46666.1 - 2.3e-70 237.7 0.1 9.5e-67 225.8 0.1 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) Glyco_hydro_18 PF00704.28 KXG46667.1 - 2.5e-63 214.7 1.2 4e-63 214.0 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KXG46667.1 - 4.6e-10 39.8 29.7 1.7e-09 38.0 5.2 6.9 6 0 0 6 6 6 3 Chitin recognition protein DUF1344 PF07076.11 KXG46667.1 - 0.074 13.0 0.1 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) Pectate_lyase_3 PF12708.7 KXG46668.1 - 7.8e-91 303.7 14.5 3.3e-77 259.1 2.9 3.3 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KXG46668.1 - 1.8e-05 24.3 4.5 0.075 12.7 0.2 3.7 4 0 0 4 4 4 2 N terminal extension of bacteriophage endosialidase LysM PF01476.20 KXG46668.1 - 5e-05 23.3 0.0 0.006 16.6 0.0 3.4 3 0 0 3 3 3 1 LysM domain TPH PF13868.6 KXG46669.1 - 0.02 13.4 2.3 0.029 12.9 2.3 1.2 1 0 0 1 1 1 0 Trichohyalin-plectin-homology domain HlyIII PF03006.20 KXG46671.1 - 7.7e-05 22.5 2.6 0.00011 21.9 2.6 1.2 1 0 0 1 1 1 1 Haemolysin-III related F-box-like PF12937.7 KXG46672.1 - 1e-05 25.3 1.4 1e-05 25.3 1.4 2.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KXG46672.1 - 0.0058 16.5 0.9 0.015 15.1 0.9 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXG46672.1 - 0.069 13.0 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 F-box Tri3 PF07428.11 KXG46673.1 - 0.0052 15.8 0.0 0.19 10.6 0.0 2.1 2 0 0 2 2 2 2 15-O-acetyltransferase Tri3 Condensation PF00668.20 KXG46673.1 - 0.0058 15.4 0.1 0.11 11.2 0.0 2.2 2 1 0 2 2 2 1 Condensation domain AATase PF07247.12 KXG46673.1 - 0.02 13.4 0.0 1.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Alcohol acetyltransferase TPP_enzyme_N PF02776.18 KXG46674.1 - 6.7e-35 120.2 0.1 2.5e-34 118.4 0.0 2.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ADH_zinc_N PF00107.26 KXG46674.1 - 2.4e-22 79.3 0.2 5.3e-22 78.2 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPP_enzyme_C PF02775.21 KXG46674.1 - 1.4e-16 60.6 0.2 4.7e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXG46674.1 - 9.5e-16 57.8 0.0 1.8e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain ADH_N PF08240.12 KXG46674.1 - 5.9e-07 29.3 2.8 8.7e-07 28.8 1.4 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXG46674.1 - 0.00039 21.5 0.0 0.0017 19.4 0.0 2.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXG46674.1 - 0.053 13.0 0.2 0.11 11.9 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase ACP_syn_III_C PF08541.10 KXG46674.1 - 0.075 13.2 0.1 0.51 10.6 0.1 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAD_binding_8 PF08022.12 KXG46675.1 - 0.031 14.4 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD-binding domain Ferric_reduct PF01794.19 KXG46675.1 - 0.49 10.5 11.6 3.6 7.7 11.6 2.5 1 1 0 1 1 1 0 Ferric reductase like transmembrane component cNMPbd_u2 PF16643.5 KXG46676.1 - 3.4e-37 128.3 10.1 7.5e-37 127.2 10.1 1.5 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 KXG46676.1 - 4.9e-36 122.7 0.0 6.7e-22 77.4 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.6 KXG46676.1 - 4.3e-11 41.9 5.8 0.91 9.7 0.0 8.2 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.7 KXG46676.1 - 2.6e-09 37.2 1.0 0.12 12.8 0.2 6.6 6 1 2 8 8 8 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KXG46676.1 - 3.5e-06 26.8 0.2 1e-05 25.3 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXG46676.1 - 1.8e-05 24.5 3.0 2.4e-05 24.1 1.0 2.3 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 KXG46676.1 - 0.0008 19.6 6.2 65 4.7 0.0 7.9 8 0 0 8 8 8 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 KXG46676.1 - 0.066 13.5 0.7 4.4 7.6 0.1 3.1 3 0 0 3 3 3 0 Ste50p, sterile alpha motif Kinesin PF00225.23 KXG46679.1 - 8.2e-116 386.6 0.2 1.9e-115 385.3 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXG46679.1 - 2.1e-26 92.6 0.0 4.9e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding AAA_33 PF13671.6 KXG46679.1 - 0.013 15.6 2.5 0.14 12.3 0.0 3.6 4 0 0 4 4 4 0 AAA domain PMSR PF01625.21 KXG46680.1 - 9.2e-61 204.5 0.2 1.1e-60 204.3 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Vsr PF03852.15 KXG46680.1 - 0.055 13.3 0.1 3.2 7.7 0.0 2.3 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr Abhydrolase_6 PF12697.7 KXG46681.1 - 5.4e-11 43.5 0.2 9.7e-11 42.7 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG46681.1 - 3.5e-09 36.7 1.0 5.1e-08 32.9 1.2 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG46681.1 - 8.1e-09 35.1 0.0 3.5e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 KXG46681.1 - 0.00019 21.1 0.7 1.1 8.7 0.1 3.2 2 2 1 3 3 3 2 Dienelactone hydrolase family DUF2048 PF09752.9 KXG46681.1 - 0.022 13.9 0.3 0.052 12.6 0.2 1.6 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Lipase_3 PF01764.25 KXG46681.1 - 0.1 12.5 0.5 0.31 10.9 0.3 1.8 2 0 0 2 2 2 0 Lipase (class 3) TRP PF06011.12 KXG46683.1 - 3.8e-131 437.7 23.3 4.5e-131 437.5 23.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXG46683.1 - 1.6e-33 116.0 0.1 2.4e-33 115.4 0.1 1.3 1 0 0 1 1 1 1 ML-like domain Sugar_tr PF00083.24 KXG46684.1 - 8.8e-133 443.5 23.4 1e-132 443.3 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG46684.1 - 1.5e-24 86.6 40.4 2.9e-18 65.9 18.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily APG5 PF04106.12 KXG46685.1 - 1.4e-61 208.0 0.0 1.7e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Ank_2 PF12796.7 KXG46686.1 - 7.9e-56 186.6 10.5 2.4e-13 50.5 0.3 6.9 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG46686.1 - 9.9e-51 169.5 14.8 9.7e-13 48.4 0.1 10.8 3 3 8 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 KXG46686.1 - 3.1e-46 153.9 19.9 3.4e-05 24.1 0.3 13.2 13 0 0 13 13 13 10 Ankyrin repeat Ank_3 PF13606.6 KXG46686.1 - 1.3e-43 141.9 13.9 0.0003 21.0 0.0 13.2 13 2 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.6 KXG46686.1 - 3.3e-38 129.2 12.2 1.4e-06 28.4 0.2 9.0 5 4 4 9 9 9 8 Ankyrin repeats (many copies) NACHT PF05729.12 KXG46686.1 - 3.8e-07 30.2 0.0 1.4e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXG46686.1 - 1.3e-05 25.4 0.0 5.3e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXG46686.1 - 0.0011 19.4 0.0 0.0035 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KXG46686.1 - 0.0034 17.8 0.0 0.05 14.0 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KXG46686.1 - 0.12 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SAM_2 PF07647.17 KXG46687.1 - 6.1e-12 45.5 0.0 1.5e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXG46687.1 - 8.3e-09 35.8 0.1 3e-08 34.0 0.1 2.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 KXG46687.1 - 3.7e-08 33.8 0.1 1.8e-07 31.6 0.1 2.3 2 0 0 2 2 2 1 PH domain SAM_3 PF18016.1 KXG46687.1 - 1.2e-05 25.1 1.0 0.0018 18.1 0.0 3.9 4 0 0 4 4 4 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KXG46687.1 - 0.017 15.4 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif PH_11 PF15413.6 KXG46687.1 - 0.018 15.4 0.2 0.045 14.2 0.2 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain SAM_PNT PF02198.16 KXG46687.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Fungal_trans_2 PF11951.8 KXG46688.1 - 6.2e-89 298.5 0.2 7.3e-89 298.2 0.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain SHR3_chaperone PF08229.11 KXG46691.1 - 1.2e-78 262.4 0.0 1.5e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5453 PF17534.2 KXG46691.1 - 0.046 13.7 0.1 0.087 12.8 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5453) Arrestin_N PF00339.29 KXG46692.1 - 1e-14 54.8 0.0 5.7e-14 52.4 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KXG46692.1 - 1.1e-08 35.7 0.0 7.6e-06 26.4 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Mnd1 PF03962.15 KXG46693.1 - 5e-22 77.9 0.0 1.5e-21 76.4 0.0 1.8 2 0 0 2 2 2 1 Mnd1 HTH domain ATG16 PF08614.11 KXG46693.1 - 0.78 9.9 8.9 20 5.3 0.0 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) UAF_Rrn10 PF05234.11 KXG46694.1 - 2.3e-05 24.6 0.0 4.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 UAF complex subunit Rrn10 WD40 PF00400.32 KXG46695.1 - 1.2e-18 67.1 17.8 8e-05 23.3 0.8 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG46695.1 - 3.1e-08 33.8 0.1 0.085 13.2 0.0 4.6 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain baeRF_family2 PF18844.1 KXG46697.1 - 0.12 12.4 0.6 0.24 11.5 0.6 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 Trypan_PARP PF05887.11 KXG46697.1 - 0.29 11.1 63.7 0.22 11.5 12.5 4.6 4 0 0 4 4 4 0 Procyclic acidic repetitive protein (PARP) HRXXH PF13933.6 KXG46698.1 - 1.2e-109 365.6 0.0 1.8e-109 365.0 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 KXG46698.1 - 0.00013 22.6 0.1 0.00013 22.6 0.1 1.9 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase PDZ_1 PF12812.7 KXG46698.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 PDZ-like domain Sporozoite_P67 PF05642.11 KXG46698.1 - 0.13 10.3 0.1 0.16 10.0 0.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Zip PF02535.22 KXG46699.1 - 1.5e-38 132.8 16.6 1.5e-38 132.8 16.6 2.2 2 0 0 2 2 2 1 ZIP Zinc transporter ArAE_2_N PF10337.9 KXG46699.1 - 0.95 8.4 4.1 2.6 7.0 4.1 1.8 1 1 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Acetyltransf_10 PF13673.7 KXG46700.1 - 2.7e-09 37.0 0.0 4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG46700.1 - 2.7e-08 34.0 0.0 3.9e-08 33.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXG46700.1 - 3.4e-08 33.8 0.0 5.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXG46700.1 - 1.7e-05 24.9 0.0 0.00054 20.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG46700.1 - 0.0011 18.9 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXG46700.1 - 0.0016 18.5 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Adeno_E3B PF03376.14 KXG46701.1 - 0.39 11.0 2.2 1.3 9.3 0.4 2.6 2 2 1 3 3 3 0 Adenovirus E3B protein MFS_1 PF07690.16 KXG46703.1 - 1.2e-31 110.0 39.8 1.2e-31 110.0 39.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG46703.1 - 1.1e-08 34.5 31.5 2.7e-07 29.8 11.4 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter Peptidase_S10 PF00450.22 KXG46704.1 - 2.8e-91 307.0 0.0 3.7e-91 306.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Myotub-related PF06602.14 KXG46704.1 - 0.039 12.9 0.1 0.064 12.2 0.1 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain MFS_1 PF07690.16 KXG46705.1 - 2.3e-30 105.7 33.7 3.5e-20 72.2 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG46705.1 - 1.5e-16 60.3 16.3 4e-16 58.9 16.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.25 KXG46706.1 - 9.7e-74 248.0 0.0 1.4e-73 247.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG46706.1 - 2.8e-36 125.1 0.0 7.3e-36 123.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG46706.1 - 0.0075 15.6 1.2 6.5 6.0 0.0 3.6 4 0 0 4 4 4 2 Kinase-like APH PF01636.23 KXG46706.1 - 0.012 15.6 0.0 1.3 8.8 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXG46706.1 - 0.018 13.9 0.0 0.061 12.1 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 KXG46706.1 - 0.043 13.2 0.0 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rieske_3 PF18465.1 KXG46707.1 - 0.11 12.7 0.0 0.31 11.3 0.0 1.7 2 0 0 2 2 2 0 Rieske 3Fe-4S DUF737 PF05300.11 KXG46708.1 - 0.035 14.5 4.7 0.045 14.1 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) p450 PF00067.22 KXG46709.1 - 2.4e-37 128.8 0.0 4.6e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KXG46709.1 - 2.9e-08 33.1 0.6 4.9e-08 32.3 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GRDP-like PF07173.12 KXG46710.1 - 4.1e-20 72.9 1.1 2.4e-13 51.0 0.1 2.7 2 1 0 2 2 2 2 Glycine-rich domain-containing protein-like Methyltransf_16 PF10294.9 KXG46712.1 - 9.5e-11 41.7 0.0 1.2e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 KXG46712.1 - 0.021 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 KXG46713.1 - 2e-12 47.2 0.0 3.6e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KXG46713.1 - 1.1e-10 41.6 0.0 1.7e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG46713.1 - 6.2e-08 33.3 0.0 1.8e-06 28.6 0.0 2.3 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG46713.1 - 8.8e-08 32.7 0.0 8.2e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXG46713.1 - 1.5e-05 25.7 0.6 4.8e-05 24.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXG46713.1 - 0.0004 20.4 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXG46713.1 - 0.0027 17.3 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KXG46713.1 - 0.0051 16.4 0.0 0.011 15.3 0.0 1.5 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 KXG46713.1 - 0.0054 16.8 0.0 0.0081 16.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 KXG46713.1 - 0.025 14.3 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pox_MCEL PF03291.16 KXG46713.1 - 0.029 13.5 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 mRNA capping enzyme PrmA PF06325.13 KXG46713.1 - 0.18 11.2 0.0 0.32 10.3 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FAM176 PF14851.6 KXG46713.1 - 1.5 8.5 5.6 2.1 8.0 1.4 2.1 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 KXG46713.1 - 2.7 8.5 8.5 21 5.6 4.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DSPc PF00782.20 KXG46714.1 - 5.7e-23 81.2 0.0 3.7e-19 68.9 0.0 2.2 1 1 1 2 2 2 2 Dual specificity phosphatase, catalytic domain KH_1 PF00013.29 KXG46716.1 - 6.3e-41 138.0 8.7 1.9e-16 59.7 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXG46716.1 - 5e-09 35.9 11.4 0.0035 17.1 0.7 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KXG46716.1 - 3.4e-07 30.0 6.6 0.054 13.4 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KXG46716.1 - 0.00036 20.6 5.9 0.41 10.8 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain GARS_C PF02843.16 KXG46716.1 - 0.013 15.8 0.4 0.88 9.9 0.0 2.7 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain ECR1_N PF14382.6 KXG46716.1 - 0.082 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region ADH_N PF08240.12 KXG46717.1 - 7.3e-29 99.9 1.5 7.3e-29 99.9 1.5 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Yippee-Mis18 PF03226.14 KXG46717.1 - 3.3e-18 65.8 0.5 3.3e-18 65.8 0.5 1.8 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ADH_zinc_N PF00107.26 KXG46717.1 - 7.3e-18 64.8 0.0 1.9e-17 63.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KXG46717.1 - 0.00034 20.5 0.3 0.00095 19.1 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 KXG46717.1 - 0.0022 17.5 0.0 0.0041 16.6 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXG46717.1 - 0.11 13.6 0.0 0.29 12.2 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RIG-I_C-RD PF11648.8 KXG46717.1 - 0.69 10.2 4.3 0.16 12.2 0.8 1.7 2 0 0 2 2 2 0 C-terminal domain of RIG-I WD40 PF00400.32 KXG46718.1 - 3e-13 50.0 2.6 3.3 8.7 0.0 8.4 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG46718.1 - 9.9e-09 35.4 0.0 0.15 12.4 0.0 6.9 5 2 3 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KXG46718.1 - 0.00076 19.1 0.5 2.5 7.6 0.0 3.8 3 1 1 4 4 4 3 PQQ-like domain PD40 PF07676.12 KXG46718.1 - 0.0016 18.4 0.0 4.9 7.2 0.0 3.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXG46718.1 - 0.023 13.7 0.0 0.25 10.2 0.0 2.5 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cyclin_N PF00134.23 KXG46719.1 - 2.8e-36 124.1 0.2 6.7e-36 122.8 0.2 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXG46719.1 - 2.2e-13 50.4 1.0 5.4e-13 49.1 1.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain FMO-like PF00743.19 KXG46721.1 - 7.3e-18 64.3 0.0 1.7e-16 59.7 0.0 2.5 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXG46721.1 - 3.2e-09 36.9 0.0 8.9e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG46721.1 - 1.1e-06 28.2 0.0 0.42 9.8 0.0 2.9 2 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG46721.1 - 2.5e-06 27.0 0.0 0.00026 20.3 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG46721.1 - 1.5e-05 24.3 0.0 0.00071 18.8 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 KXG46721.1 - 0.019 14.3 0.0 0.6 9.3 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KXG46721.1 - 0.029 14.4 0.2 2.4 8.1 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Abhydrolase_3 PF07859.13 KXG46722.1 - 6.2e-47 160.2 0.0 8.8e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXG46722.1 - 3e-11 42.9 0.5 2.1e-10 40.1 0.5 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KXG46722.1 - 0.016 15.9 0.0 0.02 15.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family FMO-like PF00743.19 KXG46723.1 - 9.3e-17 60.6 0.7 4.3e-15 55.1 0.2 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXG46723.1 - 1.1e-07 32.0 0.0 4.3e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXG46723.1 - 0.00019 20.8 0.0 0.0015 17.8 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG46723.1 - 0.0021 17.3 0.0 0.044 12.9 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXG46723.1 - 0.093 12.7 0.2 1.5 8.7 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding S_locus_glycop PF00954.20 KXG46723.1 - 0.11 13.1 4.5 0.44 11.1 0.7 2.4 2 0 0 2 2 2 0 S-locus glycoprotein domain Glyco_hydro_2_C PF02836.17 KXG46724.1 - 1.5e-88 296.8 0.1 2.1e-88 296.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KXG46724.1 - 9.8e-24 84.1 0.0 2.6e-23 82.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KXG46724.1 - 4.7e-12 46.5 0.3 1.2e-11 45.3 0.3 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Cellulase PF00150.18 KXG46724.1 - 0.01 15.3 0.3 0.11 11.9 0.3 2.2 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) SlpA PF03217.14 KXG46724.1 - 0.038 14.6 0.0 0.1 13.2 0.0 1.7 1 0 0 1 1 1 0 Surface later protein A domain Big_5 PF13205.6 KXG46724.1 - 0.078 13.7 0.1 0.23 12.2 0.1 1.8 1 0 0 1 1 1 0 Bacterial Ig-like domain AA_permease PF00324.21 KXG46725.1 - 8.4e-92 308.2 42.5 9.6e-92 308.0 42.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG46725.1 - 8.1e-25 87.5 45.3 1e-24 87.2 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease Aconitase PF00330.20 KXG46726.1 - 2.3e-111 373.1 0.3 1.8e-110 370.1 0.3 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXG46726.1 - 7.6e-23 81.3 0.0 1.6e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Abhydrolase_3 PF07859.13 KXG46727.1 - 5.8e-22 78.6 0.0 7.1e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXG46727.1 - 0.0029 16.5 0.0 0.0045 15.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Melibiase PF02065.18 KXG46728.1 - 9e-36 123.5 0.0 1.3e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KXG46728.1 - 3.5e-09 36.6 0.0 6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Melibiase_2 PF16499.5 KXG46728.1 - 0.0022 17.2 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Glyco_hydro_31 PF01055.26 KXG46728.1 - 0.0096 15.1 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Sugar_tr PF00083.24 KXG46729.1 - 4.2e-83 279.7 19.8 6.1e-83 279.2 19.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG46729.1 - 5.6e-17 61.7 23.1 4.7e-15 55.4 17.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KXG46729.1 - 3.6e-14 52.4 0.1 6.8e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KXG46730.1 - 1.3e-71 241.8 0.0 2.1e-71 241.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF676 PF05057.14 KXG46730.1 - 1.5e-06 27.9 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KXG46730.1 - 0.01 16.4 0.0 0.025 15.2 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KXG46730.1 - 0.037 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 KXG46730.1 - 0.12 11.6 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TPR_12 PF13424.6 KXG46731.1 - 1.2e-36 124.8 7.6 6.5e-09 36.0 0.0 6.4 2 1 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 KXG46731.1 - 6.3e-34 114.9 0.0 0.0007 19.4 0.0 8.5 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_MalT PF17874.1 KXG46731.1 - 4.3e-07 29.6 1.4 0.0082 15.6 0.0 3.4 1 1 1 3 3 3 2 MalT-like TPR region NB-ARC PF00931.22 KXG46731.1 - 5.7e-07 29.0 0.0 3.1e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.6 KXG46731.1 - 2.8e-05 24.5 7.3 3.7 8.1 0.0 5.9 4 2 1 5 5 5 1 Tetratricopeptide repeat DUF676 PF05057.14 KXG46731.1 - 0.00066 19.3 0.0 0.0047 16.5 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) TPR_2 PF07719.17 KXG46731.1 - 0.00085 19.3 4.0 42 4.6 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXG46731.1 - 0.0023 18.0 3.9 11 6.5 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXG46731.1 - 0.0058 16.6 2.0 2.3 8.4 0.0 4.1 5 0 0 5 5 4 1 Tetratricopeptide repeat AAA_16 PF13191.6 KXG46731.1 - 0.12 12.8 1.1 4.4 7.7 0.0 2.7 1 1 1 2 2 2 0 AAA ATPase domain CODH_A_N PF18537.1 KXG46731.1 - 0.13 12.3 0.4 5.9 7.0 0.0 2.6 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain KCH PF16944.5 KXG46731.1 - 0.17 11.6 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 Fungal potassium channel TPR_14 PF13428.6 KXG46731.1 - 0.35 11.8 8.0 69 4.7 0.0 6.2 5 2 2 7 7 7 0 Tetratricopeptide repeat NAD_binding_10 PF13460.6 KXG46732.1 - 3.7e-11 43.3 0.0 5.3e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXG46732.1 - 1.2e-08 34.9 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Zn_clus PF00172.18 KXG46733.1 - 1.5e-08 34.6 11.2 2.8e-08 33.7 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXG46733.1 - 0.074 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain GFO_IDH_MocA PF01408.22 KXG46734.1 - 1.2e-23 84.2 0.2 2.5e-23 83.1 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXG46734.1 - 1.4e-07 31.6 0.0 3.1e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_7 PF13241.6 KXG46734.1 - 0.095 13.2 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_1 PF00667.20 KXG46735.1 - 1.1e-48 165.7 0.0 1.6e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXG46735.1 - 3.8e-28 98.5 0.0 9.8e-28 97.2 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KXG46735.1 - 1.6e-22 80.2 0.0 5.1e-22 78.6 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KXG46735.1 - 0.11 12.6 0.0 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 Ferric reductase NAD binding domain p450 PF00067.22 KXG46736.1 - 1.5e-58 198.7 0.0 1.9e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 KXG46737.1 - 4.7e-99 332.3 36.6 5.4e-99 332.1 36.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG46737.1 - 4.3e-26 91.7 46.1 5.8e-26 91.2 32.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG46738.1 - 4e-66 223.7 19.2 4.6e-66 223.5 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG46738.1 - 3e-29 102.1 49.1 4.9e-24 84.9 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG46738.1 - 7.7e-08 31.2 1.3 1.8e-07 30.0 1.3 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mannosidase_ig PF17786.1 KXG46739.1 - 2.3e-19 69.8 0.5 3e-18 66.2 0.1 2.7 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KXG46739.1 - 6.1e-13 49.4 0.0 1.3e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KXG46739.1 - 4.4e-05 23.4 0.0 0.00013 22.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain NmrA PF05368.13 KXG46741.1 - 8e-37 127.0 0.0 9.7e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG46741.1 - 1.1e-10 41.7 0.0 1.4e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXG46741.1 - 1.4e-05 24.6 0.0 2.7e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXG46741.1 - 0.013 14.6 0.1 0.082 12.0 0.1 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 KXG46741.1 - 0.045 13.7 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 KXG46741.1 - 0.059 12.4 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N PF00107.26 KXG46743.1 - 8.8e-10 38.7 0.7 1.5e-09 38.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG46743.1 - 7.6e-07 29.0 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXG46743.1 - 0.0013 19.8 0.0 0.0037 18.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KXG46743.1 - 0.0055 16.2 0.1 0.036 13.5 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Peptidase_M35 PF02102.15 KXG46744.1 - 1.4e-42 145.9 7.6 1.7e-42 145.6 7.6 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KXG46744.1 - 2.1e-33 115.9 0.3 3.9e-33 115.0 0.1 1.5 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KXG46744.1 - 0.00011 21.9 3.0 0.0014 18.3 3.0 2.0 1 1 0 1 1 1 1 Putative peptidase family GST_N_4 PF17172.4 KXG46745.1 - 5.5e-21 75.2 0.0 8.5e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KXG46745.1 - 3.3e-08 33.2 0.0 1.4e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KXG46745.1 - 9.9e-06 25.9 0.0 1.6e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KXG46745.1 - 0.00025 21.0 0.0 0.00058 19.8 0.1 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXG46745.1 - 0.0022 18.3 0.0 0.0099 16.3 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF4743 PF15916.5 KXG46746.1 - 1.3e-11 44.6 0.0 1.8e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KXG46746.1 - 3.3e-08 33.6 0.0 5.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Methyltransf_2 PF00891.18 KXG46747.1 - 4.9e-22 78.3 0.0 8.6e-22 77.5 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KXG46747.1 - 0.0014 18.6 0.2 0.0032 17.4 0.2 1.7 1 1 0 1 1 1 1 Dimerisation domain MIP PF00230.20 KXG46748.1 - 7.9e-33 114.1 3.9 9.5e-33 113.8 3.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein DMT_YdcZ PF04657.13 KXG46748.1 - 0.054 13.8 3.7 0.083 13.2 0.1 2.7 2 1 1 3 3 3 0 Putative inner membrane exporter, YdcZ RseC_MucC PF04246.12 KXG46748.1 - 1.2 9.1 2.9 1.3 9.0 0.1 2.5 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Gly-zipper_Omp PF13488.6 KXG46748.1 - 1.6 8.8 8.5 7.3 6.7 3.5 3.2 2 1 0 2 2 2 0 Glycine zipper ADH_zinc_N PF00107.26 KXG46749.1 - 1.1e-09 38.4 0.0 2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG46749.1 - 1.2e-05 25.1 0.1 5.8e-05 22.9 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.26 KXG46750.1 - 5.1e-59 199.9 0.2 1.7e-58 198.2 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXG46750.1 - 4.7e-58 196.1 0.0 1e-57 194.9 0.0 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KXG46750.1 - 1.5e-48 166.0 0.1 3.5e-48 164.8 0.1 1.6 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXG46750.1 - 2.4e-48 164.9 0.0 4.6e-48 164.0 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KXG46750.1 - 1e-35 122.3 0.0 3e-35 120.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXG46750.1 - 6.4e-20 71.7 0.0 1.7e-19 70.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KXG46750.1 - 5.2e-12 45.6 0.0 1.3e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 KXG46750.1 - 1.2e-06 28.8 0.0 6.1e-06 26.5 0.1 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KXG46750.1 - 0.00015 21.2 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain SAT PF16073.5 KXG46750.1 - 0.0042 16.8 0.9 0.1 12.3 0.0 3.1 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 KXG46750.1 - 0.0062 16.4 0.4 0.036 13.9 0.1 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.12 KXG46750.1 - 0.055 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain GPI2 PF06432.11 KXG46751.1 - 1.5 8.2 13.6 0.027 13.9 6.3 1.7 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3021 PF11457.8 KXG46751.1 - 1.6 9.1 14.6 0.03 14.7 5.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3021) DUF1129 PF06570.11 KXG46751.1 - 4.2 6.8 5.5 4.6 6.7 4.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) SdpI PF13630.6 KXG46751.1 - 6.1 7.1 8.8 1.2 9.3 1.7 2.6 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF2207 PF09972.9 KXG46751.1 - 8.2 5.1 9.7 8.9 4.9 0.5 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) AMP-binding PF00501.28 KXG46753.1 - 7.1e-77 258.8 0.0 6.8e-76 255.5 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 KXG46753.1 - 5.5e-65 219.8 0.0 1.4e-37 129.5 0.0 2.4 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KXG46753.1 - 2.9e-24 85.2 1.6 1.1e-12 48.2 0.2 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Acetyltransf_8 PF13523.6 KXG46754.1 - 1.9e-42 144.4 1.3 2.7e-42 143.9 1.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ABC_membrane PF00664.23 KXG46755.1 - 3.8e-90 302.2 32.8 2.6e-50 171.6 12.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXG46755.1 - 9.7e-67 223.7 0.0 4.7e-33 114.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXG46755.1 - 5.6e-16 58.6 0.1 2.4e-05 23.9 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXG46755.1 - 7.7e-08 32.0 0.7 0.0015 18.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KXG46755.1 - 5.8e-07 30.0 2.7 0.024 15.0 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXG46755.1 - 7.1e-07 29.6 0.3 0.074 13.3 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KXG46755.1 - 3e-05 23.8 3.5 0.026 14.2 0.1 3.4 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KXG46755.1 - 0.0001 22.2 0.0 0.088 12.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KXG46755.1 - 0.00012 21.0 0.2 0.017 13.9 0.0 2.6 3 0 0 3 3 3 1 Predicted ATPase of the ABC class APS_kinase PF01583.20 KXG46755.1 - 0.00032 20.6 0.2 0.22 11.4 0.1 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 KXG46755.1 - 0.00035 19.9 0.4 0.73 9.1 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.6 KXG46755.1 - 0.00042 20.0 0.0 1.5 8.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KXG46755.1 - 0.00099 19.3 0.0 1.8 8.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 KXG46755.1 - 0.002 18.7 0.7 2.7 8.6 0.0 3.0 2 1 1 3 3 3 1 AAA domain SbcCD_C PF13558.6 KXG46755.1 - 0.0023 18.1 0.2 3.1 8.1 0.0 3.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KXG46755.1 - 0.0031 18.1 0.0 0.65 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXG46755.1 - 0.0043 16.9 0.3 0.32 10.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KXG46755.1 - 0.0097 16.3 0.3 62 4.0 0.0 4.3 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXG46755.1 - 0.011 15.8 0.0 6.7 6.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KXG46755.1 - 0.013 15.6 0.2 2.2 8.3 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_17 PF13207.6 KXG46755.1 - 0.013 15.9 0.2 25 5.3 0.0 3.8 4 0 0 4 4 3 0 AAA domain SRP54 PF00448.22 KXG46755.1 - 0.022 14.4 0.1 3.8 7.1 0.1 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KXG46755.1 - 0.022 14.5 0.0 8.1 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXG46755.1 - 0.051 13.7 0.1 5.8 7.0 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF3987 PF13148.6 KXG46755.1 - 0.078 12.0 0.0 2.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) NB-ARC PF00931.22 KXG46755.1 - 0.15 11.3 0.2 22 4.1 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain Pyr_redox_2 PF07992.14 KXG46756.1 - 3e-23 82.5 0.0 8.7e-23 81.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG46756.1 - 7.2e-14 52.1 1.6 5.8e-12 46.0 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG46756.1 - 4e-06 26.3 0.0 0.00023 20.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG46756.1 - 0.00013 21.3 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXG46756.1 - 0.0048 16.9 0.6 0.51 10.3 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXG46756.1 - 0.0068 15.5 0.1 0.021 13.9 0.0 1.7 1 1 1 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KXG46756.1 - 0.011 15.3 0.1 0.39 10.2 0.1 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXG46756.1 - 0.015 14.6 0.0 0.16 11.2 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 KXG46756.1 - 0.03 13.6 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KXG46756.1 - 0.044 12.6 0.1 2 7.2 0.4 2.7 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.14 KXG46756.1 - 0.27 9.9 0.4 0.81 8.3 0.1 1.9 3 0 0 3 3 3 0 HI0933-like protein Acetyltransf_7 PF13508.7 KXG46757.1 - 4.4e-12 46.2 0.0 7.4e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG46757.1 - 1.6e-11 44.4 0.0 2.8e-11 43.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXG46757.1 - 6e-11 42.4 0.0 1.1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXG46757.1 - 0.00053 20.1 0.0 0.0018 18.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXG46757.1 - 0.0017 18.4 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KXG46757.1 - 0.069 13.1 0.0 0.31 11.0 0.0 2.0 1 1 0 1 1 1 0 FR47-like protein Arylsulfotran_2 PF14269.6 KXG46758.1 - 1.7e-118 395.4 3.3 2.5e-118 394.8 3.3 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXG46758.1 - 6.6e-12 45.0 1.7 1.7e-10 40.4 1.7 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MFS_1 PF07690.16 KXG46759.1 - 1.5e-17 63.5 60.7 4.6e-12 45.5 33.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG46759.1 - 5.7e-13 48.2 29.4 8.2e-13 47.6 29.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 KXG46759.1 - 0.011 15.8 3.0 0.066 13.4 3.0 2.4 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 LAX PF15681.5 KXG46759.1 - 0.075 11.8 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 Lymphocyte activation family X TRI5 PF06330.11 KXG46760.1 - 9.4e-33 113.6 0.1 1.2e-32 113.2 0.1 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) AA_permease PF00324.21 KXG46761.1 - 6.3e-136 453.7 45.0 7.7e-136 453.5 45.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG46761.1 - 4.7e-34 117.9 52.3 5.6e-34 117.7 52.3 1.0 1 0 0 1 1 1 1 Amino acid permease CPL PF08144.11 KXG46764.1 - 1.5e-27 96.7 0.0 1.5e-27 96.7 0.0 4.0 5 0 0 5 5 5 2 CPL (NUC119) domain Zn_clus PF00172.18 KXG46766.1 - 0.0039 17.3 4.7 0.01 16.0 4.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TF_Zn_Ribbon PF08271.12 KXG46766.1 - 0.03 13.8 0.8 0.3 10.7 0.0 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-BED PF02892.15 KXG46766.1 - 0.037 14.1 0.3 0.091 12.8 0.3 1.7 1 0 0 1 1 1 0 BED zinc finger DNA_pol_B_palm PF14792.6 KXG46767.1 - 6.9e-35 119.7 0.0 1.7e-34 118.4 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KXG46767.1 - 1.3e-25 89.4 0.0 3.2e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KXG46767.1 - 2.4e-19 69.5 0.4 5.2e-19 68.4 0.4 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KXG46767.1 - 1.8e-16 59.7 0.1 5.9e-16 58.0 0.1 2.0 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda BRCT PF00533.26 KXG46767.1 - 1.8e-05 25.0 0.0 0.0016 18.8 0.0 2.9 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain KfrA_N PF11740.8 KXG46767.1 - 0.034 14.8 0.1 0.13 13.0 0.1 1.9 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term NTP_transf_2 PF01909.23 KXG46767.1 - 0.06 13.6 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain PTCB-BRCT PF12738.7 KXG46767.1 - 0.077 13.0 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 twin BRCT domain ATP-synt_10 PF05176.14 KXG46768.1 - 3.9e-82 275.4 0.0 5e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein V-SNARE_C PF12352.8 KXG46769.1 - 1.6e-11 44.3 0.0 1.6e-11 44.3 0.0 2.4 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.6 KXG46769.1 - 0.0076 15.0 5.4 0.011 14.5 5.4 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Syntaxin-6_N PF09177.11 KXG46769.1 - 0.059 13.9 4.9 0.18 12.3 4.8 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal STAT_alpha PF01017.20 KXG46769.1 - 0.093 12.6 3.4 0.093 12.6 1.5 1.8 1 1 1 2 2 2 0 STAT protein, all-alpha domain TIP120 PF08623.10 KXG46769.1 - 0.11 12.3 0.5 0.17 11.7 0.5 1.3 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) CENP-H PF05837.12 KXG46769.1 - 0.16 12.4 7.4 0.091 13.2 4.4 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Not3 PF04065.15 KXG46769.1 - 0.19 11.1 2.7 1.1 8.6 0.9 1.9 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component FUSC PF04632.12 KXG46769.1 - 5.6 5.4 7.4 7 5.0 7.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ribosomal_L29 PF00831.23 KXG46770.1 - 8.4e-18 64.1 0.9 8.4e-18 64.1 0.9 2.1 2 1 1 3 3 3 1 Ribosomal L29 protein CorA PF01544.18 KXG46770.1 - 0.076 12.3 3.2 0.095 12.0 3.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Med16 PF11635.8 KXG46771.1 - 3e-203 676.9 0.0 3.8e-203 676.5 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 ANAPC4_WD40 PF12894.7 KXG46771.1 - 7.3e-06 26.2 0.2 0.23 11.8 0.0 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain SIR2 PF02146.17 KXG46772.1 - 2.9e-29 102.2 0.0 9.4e-29 100.6 0.0 1.8 1 1 0 1 1 1 1 Sir2 family CBFD_NFYB_HMF PF00808.23 KXG46773.1 - 2.5e-05 24.4 0.0 4.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_60s PF00428.19 KXG46773.1 - 0.017 15.7 10.7 0.017 15.7 10.7 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein Histone PF00125.24 KXG46773.1 - 0.051 13.9 0.6 0.096 13.0 0.0 1.8 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TFIIA PF03153.13 KXG46773.1 - 0.21 11.6 9.7 0.28 11.1 9.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Na_trans_assoc PF06512.13 KXG46773.1 - 0.61 10.3 8.6 0.91 9.8 8.6 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated CENP-X PF09415.10 KXG46773.1 - 1.5 9.2 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 CENP-S associating Centromere protein X RXT2_N PF08595.11 KXG46773.1 - 2.6 8.0 11.0 0.27 11.3 6.5 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal TRAP_alpha PF03896.16 KXG46773.1 - 6.4 5.9 6.5 13 4.9 6.5 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit GN3L_Grn1 PF08701.11 KXG46774.1 - 4.7e-21 74.7 16.0 4.7e-21 74.7 16.0 2.2 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KXG46774.1 - 2.4e-18 66.3 0.1 6.4e-14 52.0 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXG46774.1 - 3.4e-07 30.3 0.1 2.9e-06 27.3 0.1 2.2 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KXG46774.1 - 1.2e-05 24.9 0.0 0.00014 21.4 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXG46774.1 - 3.2e-05 24.0 4.8 0.44 10.6 0.1 3.9 2 2 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 KXG46774.1 - 4.5e-05 23.1 0.0 0.29 10.6 0.0 2.7 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 KXG46774.1 - 0.0053 15.8 0.0 0.0053 15.8 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 KXG46774.1 - 0.006 15.9 0.1 0.12 11.6 0.0 2.4 2 0 0 2 2 2 1 AIG1 family cobW PF02492.19 KXG46774.1 - 0.019 14.5 0.0 1.3 8.6 0.0 2.8 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NOG1 PF06858.14 KXG46774.1 - 0.034 13.9 0.2 7.7 6.4 0.1 3.2 2 1 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) AAA_18 PF13238.6 KXG46774.1 - 0.052 14.1 1.4 0.14 12.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 KXG46774.1 - 0.089 13.0 0.0 22 5.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG46774.1 - 0.096 12.1 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family RNA_pol_3_Rpc31 PF11705.8 KXG46774.1 - 0.54 10.5 19.9 0.38 11.0 17.9 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 AAA_16 PF13191.6 KXG46774.1 - 0.62 10.4 0.0 0.62 10.4 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain RRN3 PF05327.11 KXG46774.1 - 0.88 8.0 4.6 1.2 7.6 4.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HEXIM PF15313.6 KXG46774.1 - 7 6.8 11.2 19 5.4 10.9 1.8 1 1 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein HAD_2 PF13419.6 KXG46775.1 - 1.6e-20 73.9 0.0 2.2e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXG46775.1 - 5e-09 36.8 0.0 1e-06 29.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXG46775.1 - 2e-06 28.3 0.0 3.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXG46775.1 - 0.00021 21.3 0.0 0.00038 20.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KXG46775.1 - 0.13 12.4 0.0 34 4.6 0.0 3.1 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 KXG46776.1 - 5.5e-17 61.4 3.2 1.5e-16 60.0 2.4 2.2 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KXG46776.1 - 3.5e-06 26.8 0.5 9.6e-06 25.4 0.5 1.8 1 0 0 1 1 1 1 Homeobox KN domain DUF4638 PF15472.6 KXG46776.1 - 0.096 12.4 6.0 0.17 11.6 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) His_Phos_1 PF00300.22 KXG46777.1 - 5.7e-08 32.7 0.1 2.3e-07 30.7 0.1 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CRC_subunit PF08624.10 KXG46778.1 - 2.1e-49 167.5 0.0 3.1e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit SERTA PF06031.13 KXG46779.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 SERTA motif Fungal_trans PF04082.18 KXG46781.1 - 4.5e-19 68.5 0.4 9.1e-19 67.5 0.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fumarate_red_D PF02313.17 KXG46781.1 - 0.02 15.0 0.0 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 Fumarate reductase subunit D DUF2162 PF09930.9 KXG46784.1 - 0.27 10.6 14.8 1.8 7.9 7.1 2.5 2 1 0 2 2 2 0 Predicted transporter (DUF2162) DUF3671 PF12420.8 KXG46784.1 - 4.1 7.5 11.5 0.37 10.9 2.0 2.6 1 1 1 2 2 2 0 Protein of unknown function SLD3 PF08639.10 KXG46785.1 - 1.8e-167 558.4 6.1 1.8e-167 558.4 6.1 1.5 2 0 0 2 2 2 1 DNA replication regulator SLD3 DASH_Spc19 PF08287.11 KXG46785.1 - 1.4 8.8 9.8 2.5 8.0 0.8 2.6 2 0 0 2 2 2 0 Spc19 S-AdoMet_synt_C PF02773.16 KXG46786.1 - 3.9e-67 224.5 0.3 3e-66 221.6 0.1 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KXG46786.1 - 5.3e-45 152.5 0.0 1e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KXG46786.1 - 3e-44 149.7 0.4 7.7e-44 148.4 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KXG46786.1 - 0.06 12.1 0.1 0.68 8.7 0.1 2.1 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) ATP_bind_1 PF03029.17 KXG46787.1 - 1.6e-76 257.3 0.2 1.8e-76 257.1 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 KXG46787.1 - 0.00041 20.4 0.0 0.0011 19.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXG46787.1 - 0.00077 18.6 0.1 0.0022 17.1 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 KXG46787.1 - 0.0027 18.1 0.0 0.0073 16.7 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 KXG46787.1 - 0.0032 17.8 0.1 0.062 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXG46787.1 - 0.0041 17.3 0.0 0.008 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 KXG46787.1 - 0.006 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 KXG46787.1 - 0.0073 15.5 0.3 0.049 12.8 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 KXG46787.1 - 0.0078 16.6 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXG46787.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 KXG46787.1 - 0.011 15.6 0.2 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 KXG46787.1 - 0.013 15.0 0.1 5.5 6.5 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TsaE PF02367.17 KXG46787.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 KXG46787.1 - 0.017 14.4 0.0 0.038 13.2 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain AAA_30 PF13604.6 KXG46787.1 - 0.018 14.8 0.1 0.069 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXG46787.1 - 0.022 14.3 0.0 0.05 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KXG46787.1 - 0.026 15.1 0.0 0.073 13.6 0.0 1.7 2 0 0 2 2 1 0 ABC transporter AAA_22 PF13401.6 KXG46787.1 - 0.028 14.7 0.0 0.067 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXG46787.1 - 0.029 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KXG46787.1 - 0.03 14.9 0.0 0.062 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXG46787.1 - 0.031 14.0 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain ArsA_ATPase PF02374.15 KXG46787.1 - 0.036 13.2 0.2 0.086 12.0 0.0 1.6 2 0 0 2 2 2 0 Anion-transporting ATPase RuvB_N PF05496.12 KXG46787.1 - 0.038 13.8 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_31 PF13614.6 KXG46787.1 - 0.042 13.8 0.0 4.3 7.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXG46787.1 - 0.045 13.5 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KXG46787.1 - 0.05 13.2 0.1 0.98 9.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KXG46787.1 - 0.061 13.4 0.0 0.19 11.8 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.18 KXG46787.1 - 0.064 12.5 0.0 0.13 11.5 0.0 1.5 2 0 0 2 2 1 0 Septin ATPase_2 PF01637.18 KXG46787.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KXG46787.1 - 0.094 12.7 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 KXG46787.1 - 0.095 12.4 0.0 0.51 10.0 0.0 2.1 2 1 0 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.12 KXG46787.1 - 0.098 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 KXG46787.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KXG46787.1 - 0.12 11.7 0.0 0.3 10.4 0.0 1.6 2 0 0 2 2 1 0 KaiC IstB_IS21 PF01695.17 KXG46787.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein CbiA PF01656.23 KXG46787.1 - 0.19 11.8 0.0 0.27 11.3 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Apq12 PF12716.7 KXG46788.1 - 8.8e-20 70.4 14.1 8.8e-20 70.4 14.1 1.6 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis Filament PF00038.21 KXG46789.1 - 0.00026 20.7 5.3 0.00026 20.7 5.3 5.4 4 1 0 5 5 5 3 Intermediate filament protein MatP_C PF17414.2 KXG46789.1 - 0.03 14.5 2.2 0.22 11.7 1.8 2.9 2 0 0 2 2 2 0 MatP C-terminal ribbon-helix-helix domain Borrelia_orfA PF02414.15 KXG46789.1 - 4.5 6.8 5.5 7.3 6.2 2.6 2.2 2 0 0 2 2 2 0 Borrelia ORF-A TMF_TATA_bd PF12325.8 KXG46792.1 - 7.2e-40 135.8 10.9 7.2e-40 135.8 10.9 6.4 2 1 4 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KXG46792.1 - 4.4e-19 68.3 14.2 4.4e-19 68.3 14.2 9.0 5 3 3 9 9 9 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KXG46792.1 - 1.5e-05 25.3 2.9 1.5e-05 25.3 2.9 5.8 3 1 3 6 6 6 3 Autophagy protein 16 (ATG16) BST2 PF16716.5 KXG46792.1 - 0.0086 16.6 5.9 0.0086 16.6 5.9 8.0 3 2 7 10 10 10 3 Bone marrow stromal antigen 2 DASH_Dam1 PF08653.10 KXG46792.1 - 0.47 10.3 4.5 6.1 6.7 0.1 4.2 2 2 2 4 4 4 0 DASH complex subunit Dam1 NPV_P10 PF05531.12 KXG46792.1 - 0.73 10.3 30.7 0.45 11.0 1.2 6.5 6 1 0 6 6 6 0 Nucleopolyhedrovirus P10 protein V-ATPase_H_N PF03224.14 KXG46793.1 - 1.1e-80 271.3 0.0 2.1e-80 270.4 0.0 1.5 1 0 0 1 1 1 1 V-ATPase subunit H Fungal_trans_2 PF11951.8 KXG46793.1 - 7.2e-59 199.5 4.2 5.3e-58 196.7 2.8 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain V-ATPase_H_C PF11698.8 KXG46793.1 - 2.2e-32 111.6 0.0 8.1e-32 109.8 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H Hydrophobin PF01185.18 KXG46794.1 - 0.0024 18.5 8.8 0.0037 17.9 8.8 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.18 KXG46794.1 - 0.025 14.9 7.8 0.026 14.8 2.7 2.2 2 0 0 2 2 2 0 Granulin PhnA PF03831.14 KXG46794.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 PhnA domain Granulin PF00396.18 KXG46795.1 - 0.0056 17.0 2.7 0.0056 17.0 2.7 2.2 2 0 0 2 2 2 1 Granulin Hydrophobin PF01185.18 KXG46795.1 - 0.0076 16.9 7.3 0.012 16.3 7.3 1.3 1 0 0 1 1 1 1 Fungal hydrophobin MFS_1 PF07690.16 KXG46796.1 - 3e-31 108.6 36.1 3e-31 108.6 36.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily His_Phos_2 PF00328.22 KXG46797.1 - 9.4e-05 21.9 0.0 0.035 13.5 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Retrotran_gag_2 PF14223.6 KXG46799.1 - 1.3e-07 31.4 0.2 2.1e-07 30.7 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KXG46799.1 - 0.024 14.5 0.1 0.2 11.5 0.0 2.3 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KXG46799.1 - 0.03 14.0 0.1 0.03 14.0 0.1 3.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4219) Ank_2 PF12796.7 KXG46800.1 - 6e-45 151.7 0.9 7.4e-14 52.1 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXG46800.1 - 6.2e-34 115.6 0.2 3.7e-09 36.6 0.0 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXG46800.1 - 6.7e-31 106.3 0.2 1.8e-09 37.9 0.0 5.1 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG46800.1 - 4.6e-27 91.1 0.1 0.0027 18.1 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KXG46800.1 - 8.5e-23 79.8 0.2 0.0013 19.1 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Shal-type PF11601.8 KXG46800.1 - 0.43 10.2 1.4 0.63 9.6 0.1 2.0 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels, N-terminal WD40 PF00400.32 KXG46801.1 - 1.3e-45 152.5 15.4 2.8e-09 37.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG46801.1 - 7.5e-07 29.4 0.5 4 7.8 0.1 5.1 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXG46801.1 - 0.0042 16.4 0.0 0.0098 15.2 0.0 1.6 2 0 0 2 2 2 1 WD40-like domain DUF5018 PF16410.5 KXG46801.1 - 0.021 13.5 0.0 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) Nup160 PF11715.8 KXG46801.1 - 0.031 12.9 2.5 11 4.6 0.0 4.2 1 1 4 5 5 5 0 Nucleoporin Nup120/160 AAA PF00004.29 KXG46802.1 - 3.8e-15 56.5 0.0 7.3e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KXG46802.1 - 6.4e-12 45.5 0.9 3.7e-11 43.0 0.8 2.2 1 1 1 2 2 2 1 AAA lid domain AAA_22 PF13401.6 KXG46802.1 - 2.1e-09 37.8 0.0 8.6e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXG46802.1 - 1.2e-08 35.5 1.6 6.3e-08 33.2 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain BAH PF01426.18 KXG46802.1 - 3.6e-05 23.6 0.0 8.6e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_28 PF13521.6 KXG46802.1 - 0.0024 18.1 0.0 0.0086 16.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXG46802.1 - 0.0032 17.8 0.0 0.0076 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXG46802.1 - 0.011 15.6 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KXG46802.1 - 0.023 13.9 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 KXG46802.1 - 0.027 15.0 0.2 0.086 13.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_32 PF13654.6 KXG46802.1 - 0.028 13.2 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain ssDBP PF17878.1 KXG46802.1 - 0.031 14.5 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Single-stranded DNA-binding protein PIF1 PF05970.14 KXG46802.1 - 0.044 12.9 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Kinesin PF00225.23 KXG46802.1 - 0.053 12.4 0.0 0.088 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain NACHT PF05729.12 KXG46802.1 - 0.071 13.0 0.0 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KXG46802.1 - 0.087 12.7 0.0 1.4 8.8 0.0 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KXG46802.1 - 0.13 12.6 0.1 0.43 11.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase NB-ARC PF00931.22 KXG46802.1 - 0.17 11.1 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Pex14_N PF04695.13 KXG46802.1 - 1.9 9.1 6.0 47 4.6 0.3 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region KH_1 PF00013.29 KXG46803.1 - 0.0041 16.9 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 KH domain Prefoldin PF02996.17 KXG46804.1 - 2e-26 92.3 0.4 2.5e-26 91.9 0.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KXG46804.1 - 0.00091 19.2 1.6 0.025 14.5 0.6 2.1 2 0 0 2 2 2 1 Prefoldin subunit Med30 PF11315.8 KXG46804.1 - 0.038 14.2 0.2 0.54 10.5 0.2 2.0 2 0 0 2 2 2 0 Mediator complex subunit 30 CLZ PF16526.5 KXG46804.1 - 0.07 13.5 4.2 3.3 8.1 0.3 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Sec2p PF06428.11 KXG46804.1 - 0.079 12.9 1.9 0.88 9.6 0.3 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 KXG46804.1 - 0.097 12.9 1.1 4.5 7.5 0.4 2.0 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DASH_Hsk3 PF08227.11 KXG46804.1 - 0.15 12.4 4.2 0.24 11.8 0.0 2.4 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like Fungal_trans PF04082.18 KXG46805.1 - 0.00034 19.7 0.1 0.00075 18.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain PPP4R2 PF09184.11 KXG46806.1 - 1.7 8.1 25.8 2.5 7.6 25.8 1.3 1 0 0 1 1 1 0 PPP4R2 Sugar_tr PF00083.24 KXG46807.1 - 1.6e-84 284.4 22.1 1.9e-84 284.1 22.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG46807.1 - 1.3e-12 47.4 31.4 1.3e-12 47.4 31.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4880 PF16220.5 KXG46807.1 - 0.086 12.7 0.5 0.24 11.3 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) RIO1 PF01163.22 KXG46808.1 - 0.00063 19.4 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KXG46808.1 - 0.0029 17.0 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXG46808.1 - 0.0032 17.4 0.1 0.027 14.4 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXG46808.1 - 0.01 15.2 0.0 0.042 13.2 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXG46808.1 - 0.025 13.4 0.0 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KXG46808.1 - 0.092 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Acetyltransf_10 PF13673.7 KXG46809.1 - 6.2e-13 48.8 0.0 9.9e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG46809.1 - 8.2e-13 48.6 0.1 1.3e-12 47.9 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXG46809.1 - 1.5e-10 41.4 0.0 2.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXG46809.1 - 0.0044 17.1 0.0 0.015 15.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXG46809.1 - 0.0046 17.0 0.0 0.008 16.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase tRNA-synt_2b PF00587.25 KXG46810.1 - 3.7e-30 105.2 0.0 4.8e-29 101.6 0.0 2.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXG46810.1 - 2.7e-12 46.7 0.0 6.4e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain CBF PF03914.17 KXG46811.1 - 1.1e-56 191.6 0.2 6.8e-56 188.9 0.1 2.5 2 0 0 2 2 2 1 CBF/Mak21 family Aa_trans PF01490.18 KXG46812.1 - 3.7e-25 88.5 35.1 4.7e-25 88.1 35.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GCV_T PF01571.21 KXG46813.1 - 1.2e-78 264.0 0.0 1.6e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KXG46813.1 - 5.3e-16 58.3 0.3 1.2e-15 57.2 0.3 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain LVIVD PF08309.11 KXG46813.1 - 0.0031 16.8 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 LVIVD repeat Glyco_hydro_92 PF07971.12 KXG46814.1 - 3.6e-144 481.1 0.6 4.3e-144 480.9 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXG46814.1 - 2.9e-62 210.7 1.0 2.9e-62 210.7 1.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain 4HBT PF03061.22 KXG46815.1 - 2.9e-10 40.4 0.0 5e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily APS_kinase PF01583.20 KXG46816.1 - 5.9e-73 244.0 0.0 7.2e-73 243.7 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KXG46816.1 - 7.2e-07 29.5 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXG46816.1 - 2.2e-05 25.0 0.0 4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXG46816.1 - 0.00099 19.5 0.0 0.0015 19.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 KXG46816.1 - 0.0066 15.9 0.0 0.0076 15.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 PEPCK_ATP PF01293.20 KXG46816.1 - 0.06 12.0 0.0 0.082 11.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.6 KXG46816.1 - 0.083 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KXG46816.1 - 0.091 12.0 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.12 KXG46816.1 - 0.097 12.2 0.0 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 KXG46816.1 - 0.1 12.9 0.0 0.56 10.5 0.0 1.9 1 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 KXG46816.1 - 0.16 11.1 0.1 0.29 10.2 0.1 1.4 1 1 0 1 1 1 0 G-protein alpha subunit V-ATPase_C PF03223.15 KXG46817.1 - 2.7e-127 425.2 0.1 3e-127 425.1 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C NMT PF01233.19 KXG46817.1 - 0.044 13.6 0.3 0.088 12.6 0.3 1.4 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain mRNA_cap_C PF03919.15 KXG46817.1 - 0.097 13.3 0.1 0.29 11.8 0.1 1.8 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain RhoGAP PF00620.27 KXG46818.1 - 5.7e-47 159.3 0.0 2e-46 157.6 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KXG46818.1 - 5e-15 55.5 19.6 7e-10 39.0 2.5 2.4 2 0 0 2 2 2 2 LIM domain CENP-H PF05837.12 KXG46818.1 - 0.0043 17.4 4.2 0.0043 17.4 4.2 2.8 2 0 0 2 2 2 1 Centromere protein H (CENP-H) FLYWCH_u PF16662.5 KXG46818.1 - 0.0064 16.5 0.3 0.47 10.5 0.1 2.7 2 0 0 2 2 2 1 FLYWCH-type zinc finger-containing protein 1 zf-C4H2 PF10146.9 KXG46818.1 - 0.015 15.7 0.3 0.015 15.7 0.3 2.8 3 1 0 3 3 2 0 Zinc finger-containing protein FlgN PF05130.12 KXG46818.1 - 0.24 11.9 10.2 0.12 12.9 5.8 2.4 2 0 0 2 2 2 0 FlgN protein bZIP_Maf PF03131.17 KXG46818.1 - 0.25 11.9 9.9 0.21 12.1 3.2 2.7 2 0 0 2 2 2 0 bZIP Maf transcription factor 5_nucleotid PF05761.14 KXG46818.1 - 0.32 9.8 4.2 0.58 9.0 4.2 1.3 1 0 0 1 1 1 0 5' nucleotidase family CENP-F_leu_zip PF10473.9 KXG46818.1 - 1.5 8.9 18.7 0.083 12.9 6.1 3.3 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.6 KXG46818.1 - 1.8 8.9 14.0 0.16 12.3 5.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Zn-ribbon_8 PF09723.10 KXG46818.1 - 9.1 6.5 19.9 0.76 9.9 1.5 4.1 3 1 1 4 4 4 0 Zinc ribbon domain FKBP_C PF00254.28 KXG46819.1 - 2.6e-28 98.2 0.0 3e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4879 PF16219.5 KXG46819.1 - 0.098 12.9 0.0 17 5.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4879) AP_endonuc_2 PF01261.24 KXG46820.1 - 1.7e-31 109.3 0.1 2.3e-31 108.9 0.1 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel GFO_IDH_MocA PF01408.22 KXG46821.1 - 9.8e-25 87.7 0.0 1.4e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXG46821.1 - 2.3e-15 56.6 0.0 4.7e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 KXG46821.1 - 0.0038 17.7 0.0 0.0066 16.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 KXG46821.1 - 0.028 14.9 0.0 0.054 14.0 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Ldh_1_N PF00056.23 KXG46821.1 - 0.21 11.7 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KXG46822.1 - 3.9e-138 461.1 18.9 4.5e-138 460.9 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG46822.1 - 9.6e-25 87.2 37.4 3.1e-24 85.6 29.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Shikimate_dh_N PF08501.11 KXG46825.1 - 1.8e-21 76.1 0.0 4.2e-21 75.0 0.0 1.6 1 1 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KXG46825.1 - 0.0002 21.1 0.1 0.00054 19.7 0.1 1.8 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KXG46825.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Inositol_P PF00459.25 KXG46826.1 - 2e-81 273.5 0.0 2.3e-81 273.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DHquinase_I PF01487.15 KXG46827.1 - 3.7e-37 128.8 0.0 5.5e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KXG46827.1 - 1.7e-19 70.5 0.1 9.2e-19 68.1 0.0 2.0 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KXG46827.1 - 2.1e-18 66.4 0.0 5.1e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KXG46827.1 - 3e-10 39.7 0.1 5.7e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KXG46827.1 - 2e-06 27.9 0.1 5.4e-06 26.5 0.1 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KXG46827.1 - 0.027 15.0 0.0 0.24 12.0 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AAA_16 PF13191.6 KXG46827.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KXG46827.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXG46827.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Fungal_trans PF04082.18 KXG46828.1 - 4.2e-22 78.4 0.1 8.2e-22 77.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG46828.1 - 7.6e-07 29.2 13.7 1.1e-06 28.6 13.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_II PF01220.19 KXG46829.1 - 1.1e-62 209.7 0.1 1.3e-62 209.5 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Sortilin-Vps10 PF15902.5 KXG46829.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, Arrestin_N PF00339.29 KXG46830.1 - 2.8e-05 24.2 0.4 0.037 14.1 0.1 3.1 1 1 1 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Fungal_trans_2 PF11951.8 KXG46831.1 - 3.2e-34 118.4 9.4 7.4e-34 117.2 9.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain ASXH PF13919.6 KXG46831.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Asx homology domain TPP_enzyme_N PF02776.18 KXG46834.1 - 2e-27 95.9 0.0 4.4e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ADH_zinc_N PF00107.26 KXG46834.1 - 2.2e-27 95.6 0.0 7.1e-27 93.9 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TPP_enzyme_C PF02775.21 KXG46834.1 - 3.6e-19 69.0 1.8 8e-19 67.9 0.1 2.5 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXG46834.1 - 1.4e-17 63.7 0.0 3e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain ADH_N PF08240.12 KXG46834.1 - 1.4e-05 25.0 2.0 3.1e-05 23.8 2.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXG46834.1 - 0.14 11.6 0.2 0.37 10.2 0.2 1.7 1 0 0 1 1 1 0 short chain dehydrogenase TPP_enzyme_N PF02776.18 KXG46835.1 - 1.4e-54 184.2 0.0 2.7e-54 183.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXG46835.1 - 5.8e-44 149.6 0.1 2e-43 147.8 0.1 2.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXG46835.1 - 2.5e-37 127.7 0.1 7.9e-37 126.1 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Dimer_Tnp_hAT PF05699.14 KXG46837.1 - 1.2e-08 34.6 0.0 3e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KXG46837.1 - 0.0046 17.3 0.3 0.015 15.6 0.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4413) adh_short_C2 PF13561.6 KXG46838.1 - 7.5e-39 133.7 0.1 1e-38 133.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG46838.1 - 3.5e-26 91.9 0.0 4.8e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG46838.1 - 0.00044 20.2 0.1 0.00094 19.1 0.1 1.5 1 1 0 1 1 1 1 KR domain ADH_N PF08240.12 KXG46839.1 - 5.7e-05 23.0 0.1 7e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RTA1 PF04479.13 KXG46840.1 - 1.1e-21 77.4 0.8 1.4e-21 77.0 0.8 1.1 1 0 0 1 1 1 1 RTA1 like protein HILPDA PF15220.6 KXG46840.1 - 0.12 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated Aldo_ket_red PF00248.21 KXG46841.1 - 5e-37 127.7 0.0 5.9e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Spc29 PF17082.5 KXG46842.1 - 0.011 15.6 1.4 0.018 14.9 1.4 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 NACHT PF05729.12 KXG46843.1 - 1.1e-22 80.7 0.0 1.8e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.32 KXG46843.1 - 5e-10 39.8 2.1 1.5e-09 38.3 0.1 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG46843.1 - 4e-05 23.8 0.0 0.00013 22.2 0.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ses_B PF17046.5 KXG46843.1 - 0.012 15.5 0.6 0.012 15.5 0.6 1.7 2 0 0 2 2 2 0 SesB domain on fungal death-pathway protein AAA_16 PF13191.6 KXG46843.1 - 0.075 13.4 0.0 0.18 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KXG46843.1 - 0.14 12.6 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KXG46843.1 - 0.14 12.6 0.0 0.77 10.2 0.0 2.2 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) Choline_kinase PF01633.20 KXG46845.1 - 1.3e-42 145.8 0.0 3.7e-41 141.1 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KXG46845.1 - 1.6e-08 34.7 0.5 2.3e-08 34.3 0.1 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family CHORD PF04968.12 KXG46846.1 - 1.2e-46 157.2 20.3 5.1e-27 94.4 6.2 3.2 3 0 0 3 3 3 3 CHORD CS PF04969.16 KXG46846.1 - 3.5e-14 53.6 0.0 5.3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 CS domain FAP PF07174.11 KXG46846.1 - 2.3 7.6 11.5 3.6 6.9 11.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) SBF PF01758.16 KXG46849.1 - 9.8e-49 165.7 10.6 9.8e-49 165.7 10.6 2.6 2 2 2 4 4 4 1 Sodium Bile acid symporter family Methyltransf_31 PF13847.6 KXG46850.1 - 9.6e-30 103.4 0.0 2.3e-29 102.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG46850.1 - 2.9e-19 69.6 0.0 5.2e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG46850.1 - 1.7e-17 63.8 0.0 3.3e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG46850.1 - 2.6e-15 56.4 0.0 4.8e-15 55.5 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXG46850.1 - 8.3e-11 42.0 0.0 1.6e-10 41.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXG46850.1 - 6.4e-10 38.9 0.5 2.5e-09 37.0 0.2 1.8 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KXG46850.1 - 2.8e-08 33.8 0.1 5.7e-08 32.8 0.1 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KXG46850.1 - 2.1e-06 28.4 0.0 4.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXG46850.1 - 2.6e-05 23.8 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KXG46850.1 - 6.6e-05 22.3 0.0 9.3e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KXG46850.1 - 0.00038 19.8 0.0 0.00051 19.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain UPF0020 PF01170.18 KXG46850.1 - 0.00049 19.8 0.0 0.00081 19.1 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 DOT1 PF08123.13 KXG46850.1 - 0.00051 19.6 0.1 0.00091 18.8 0.1 1.5 1 1 0 1 1 1 1 Histone methylation protein DOT1 NNMT_PNMT_TEMT PF01234.17 KXG46850.1 - 0.0027 16.9 0.1 2 7.6 0.0 2.2 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_3 PF01596.17 KXG46850.1 - 0.01 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_16 PF10294.9 KXG46850.1 - 0.013 15.2 0.1 0.021 14.6 0.1 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_15 PF09445.10 KXG46850.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 KXG46850.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KXG46850.1 - 0.047 13.6 0.0 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 KXG46850.1 - 0.067 13.3 0.0 0.21 11.7 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KXG46850.1 - 0.091 12.2 0.1 0.23 10.9 0.1 1.7 2 0 0 2 2 2 0 Putative methyltransferase Chal_sti_synt_C PF02797.15 KXG46850.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.5 1 1 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain DUF3425 PF11905.8 KXG46851.1 - 7.3e-16 58.3 0.1 1.1e-15 57.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.25 KXG46852.1 - 9.6e-22 77.4 0.0 8.3e-20 71.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG46852.1 - 1.6e-15 57.3 0.0 1.8e-14 53.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG46852.1 - 0.00026 21.0 0.0 0.00039 20.4 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF4844 PF16133.5 KXG46852.1 - 0.11 13.0 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) Peptidase_C14 PF00656.22 KXG46854.1 - 7e-05 22.9 0.1 0.0072 16.3 0.1 2.2 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KXG46854.1 - 0.027 14.4 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain 14-3-3 PF00244.20 KXG46855.1 - 4.2e-09 36.2 0.2 8.4e-09 35.3 0.1 1.5 2 0 0 2 2 2 1 14-3-3 protein Toxin_15 PF07906.13 KXG46855.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 ShET2 enterotoxin, N-terminal region Metallophos PF00149.28 KXG46856.1 - 2.1e-11 44.7 1.6 2.7e-11 44.3 0.8 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.24 KXG46857.1 - 3.3e-84 283.3 24.6 3.8e-84 283.1 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG46857.1 - 1.1e-31 110.1 23.4 1.1e-31 110.1 23.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG46857.1 - 0.0013 17.2 6.4 0.002 16.7 2.9 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KXG46857.1 - 0.21 9.9 10.7 0.18 10.2 1.4 2.6 2 1 1 3 3 3 0 Transmembrane secretion effector MFS_1 PF07690.16 KXG46858.1 - 1.2e-40 139.5 68.1 9.9e-40 136.5 64.5 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3431 PF11913.8 KXG46859.1 - 1.7e-57 194.7 0.0 2.1e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) GMC_oxred_N PF00732.19 KXG46860.1 - 2.9e-45 154.9 0.1 1.6e-44 152.5 0.1 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG46860.1 - 4e-30 105.2 0.0 6.6e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXG46860.1 - 1.9e-06 27.3 1.4 0.019 14.1 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXG46860.1 - 2.3e-06 27.4 2.8 6.8e-06 25.9 2.5 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG46860.1 - 5.8e-06 26.4 0.3 1.5e-05 25.1 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXG46860.1 - 0.00023 20.3 0.2 0.00037 19.7 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXG46860.1 - 0.024 13.9 0.3 0.12 11.6 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG46860.1 - 0.026 13.8 0.4 0.042 13.1 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXG46860.1 - 0.027 13.2 0.1 0.05 12.3 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 KXG46860.1 - 0.14 11.4 0.2 0.27 10.5 0.2 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KXG46860.1 - 0.19 11.7 1.4 1.4 8.9 0.2 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Dala_Dala_lig_C PF07478.13 KXG46862.1 - 2.2e-07 30.6 0.0 7.3e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus Methyltransf_25 PF13649.6 KXG46862.1 - 8.5e-05 23.2 0.0 0.027 15.2 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 KXG46862.1 - 0.0019 18.0 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 KXG46862.1 - 0.003 18.3 0.0 0.02 15.6 0.0 2.4 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG46862.1 - 0.013 16.2 0.0 0.22 12.2 0.0 2.8 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_23 PF13489.6 KXG46862.1 - 0.014 15.3 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Dala_Dala_lig_C PF07478.13 KXG46863.1 - 1.4e-05 24.7 0.0 0.00028 20.5 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus Methyltransf_25 PF13649.6 KXG46863.1 - 5.1e-05 23.9 0.0 0.00016 22.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG46863.1 - 0.0003 20.6 0.0 0.00076 19.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ATP-grasp_3 PF02655.14 KXG46863.1 - 0.0011 19.1 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain MTS PF05175.14 KXG46863.1 - 0.0014 18.2 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KXG46863.1 - 0.051 14.2 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain ATP-grasp_4 PF13535.6 KXG46863.1 - 0.11 12.1 0.0 2.7 7.6 0.0 2.5 2 1 0 2 2 2 0 ATP-grasp domain MetW PF07021.12 KXG46863.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW APH PF01636.23 KXG46864.1 - 8.6e-11 42.2 0.0 1.4e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KXG46864.1 - 0.022 13.7 0.0 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 KXG46864.1 - 0.059 13.0 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase AAA PF00004.29 KXG46865.1 - 3.1e-41 140.9 0.8 1e-13 51.9 0.0 5.4 6 0 0 6 6 4 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 KXG46865.1 - 4.4e-40 137.4 0.1 2.8e-39 134.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KXG46865.1 - 1.3e-27 97.3 27.3 7.1e-26 91.5 0.0 6.4 6 0 0 6 6 6 2 AAA domain AAA_lid_6 PF17866.1 KXG46865.1 - 3.6e-16 59.1 4.9 6.1e-07 29.5 0.2 3.7 3 0 0 3 3 3 2 AAA lid domain AAA_30 PF13604.6 KXG46865.1 - 9.4e-16 58.1 0.2 8e-06 25.7 0.0 5.7 5 0 0 5 5 5 3 AAA domain AAA_19 PF13245.6 KXG46865.1 - 1.5e-15 57.8 0.6 2.7e-07 31.0 0.0 5.5 4 1 0 4 4 4 2 AAA domain AAA_5 PF07728.14 KXG46865.1 - 9.7e-11 41.8 6.1 0.08 12.9 0.0 5.2 5 0 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXG46865.1 - 3e-10 40.5 5.6 0.22 11.8 0.0 6.4 4 2 0 4 4 4 2 AAA domain IstB_IS21 PF01695.17 KXG46865.1 - 3.3e-09 36.7 0.0 0.045 13.5 0.0 4.8 4 0 0 4 4 4 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KXG46865.1 - 1.6e-08 34.2 0.2 0.67 9.3 0.0 4.7 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI ResIII PF04851.15 KXG46865.1 - 9.8e-08 32.2 1.1 4.4e-05 23.5 0.1 4.8 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 KXG46865.1 - 5.3e-07 29.5 0.2 3.5 7.3 0.0 4.7 4 1 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KXG46865.1 - 6.7e-07 29.7 0.3 0.56 10.6 0.0 4.8 4 0 0 4 4 4 1 RNA helicase AAA_18 PF13238.6 KXG46865.1 - 2.9e-06 27.8 5.6 1.8 9.1 0.0 6.2 6 0 0 6 6 5 1 AAA domain Viral_helicase1 PF01443.18 KXG46865.1 - 5.1e-06 26.4 4.3 4.2 7.0 0.0 6.2 7 0 0 7 7 7 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KXG46865.1 - 2e-05 24.0 5.3 0.00071 18.9 0.0 5.1 5 1 1 6 6 6 1 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KXG46865.1 - 2.1e-05 24.3 0.2 8.4 6.1 0.0 5.3 5 1 0 5 5 5 0 Sigma-54 interaction domain AAA_16 PF13191.6 KXG46865.1 - 3e-05 24.5 18.6 0.15 12.4 0.0 6.2 7 0 0 7 7 5 3 AAA ATPase domain AAA_7 PF12775.7 KXG46865.1 - 3.5e-05 23.4 1.4 13 5.2 0.0 4.7 5 0 0 5 5 4 0 P-loop containing dynein motor region AAA_24 PF13479.6 KXG46865.1 - 7.9e-05 22.5 3.8 4 7.1 0.2 4.5 4 0 0 4 4 4 1 AAA domain PhoH PF02562.16 KXG46865.1 - 0.00014 21.4 0.2 1.6 8.1 0.0 5.0 5 0 0 5 5 5 1 PhoH-like protein AAA_28 PF13521.6 KXG46865.1 - 0.00032 21.0 2.1 7.2 6.8 0.0 5.0 4 0 0 4 4 4 0 AAA domain Adeno_IVa2 PF02456.15 KXG46865.1 - 0.00066 18.6 0.0 0.073 11.8 0.0 2.5 2 0 0 2 2 2 1 Adenovirus IVa2 protein ABC_tran PF00005.27 KXG46865.1 - 0.00073 20.1 1.6 8.2 6.9 0.0 5.0 4 0 0 4 4 4 0 ABC transporter Torsin PF06309.11 KXG46865.1 - 0.0025 17.9 0.2 22 5.2 0.0 4.2 4 0 0 4 4 4 0 Torsin SKI PF01202.22 KXG46865.1 - 0.04 14.0 2.6 16 5.6 0.0 4.5 4 0 0 4 4 4 0 Shikimate kinase AAA_29 PF13555.6 KXG46865.1 - 0.076 12.8 0.6 39 4.1 0.0 3.8 4 0 0 4 4 4 0 P-loop containing region of AAA domain ATPase PF06745.13 KXG46865.1 - 0.076 12.3 3.6 2.5 7.4 0.0 3.8 4 0 0 4 4 3 0 KaiC RsgA_GTPase PF03193.16 KXG46865.1 - 0.08 12.8 0.4 6.1 6.7 0.1 3.6 4 0 0 4 4 3 0 RsgA GTPase Helicase_RecD PF05127.14 KXG46865.1 - 0.1 12.4 0.0 0.59 10.0 0.0 2.4 2 0 0 2 2 1 0 Helicase SRP54 PF00448.22 KXG46865.1 - 0.12 11.9 4.0 0.82 9.3 0.0 3.5 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KXG46865.1 - 0.24 11.5 17.2 2.5 8.2 0.0 5.4 6 0 0 6 6 5 0 AAA domain AAA_25 PF13481.6 KXG46865.1 - 0.37 10.3 6.6 1.6 8.2 0.0 3.7 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 KXG46865.1 - 0.41 10.5 4.2 18 5.2 0.0 4.1 4 0 0 4 4 4 0 NACHT domain FliD_N PF02465.18 KXG46865.1 - 0.76 10.5 5.0 0.26 12.0 0.5 2.7 2 0 0 2 2 1 0 Flagellar hook-associated protein 2 N-terminus Vanabin-2 PF11437.8 KXG46865.1 - 0.95 9.7 15.6 2.6 8.2 15.6 1.8 1 0 0 1 1 1 0 Vanadium-binding protein 2 Glyco_hydro_3_C PF01915.22 KXG46867.1 - 6.2e-59 199.4 0.0 1.1e-58 198.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXG46867.1 - 5.6e-39 134.4 0.0 9.6e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXG46867.1 - 4.6e-25 87.5 0.0 1e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KXG46867.1 - 8.7e-16 58.0 0.0 1.9e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Sugar_tr PF00083.24 KXG46868.1 - 4.8e-73 246.5 17.9 5.9e-73 246.2 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG46868.1 - 1.3e-21 77.0 30.6 2.2e-21 76.2 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXG46868.1 - 2.7e-05 22.9 6.6 2.7e-05 22.9 6.6 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 KXG46868.1 - 0.011 14.2 1.4 0.018 13.5 1.4 1.3 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KXG46868.1 - 0.06 11.6 10.4 2 6.6 0.1 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_127 PF07944.12 KXG46870.1 - 1.4e-139 466.0 1.1 1.6e-139 465.8 1.1 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 DUF5381 PF17353.2 KXG46871.1 - 0.023 14.4 1.2 0.044 13.5 1.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5381) DUF5438 PF17506.2 KXG46871.1 - 0.036 14.4 0.8 29 5.0 0.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5438) AA_permease_2 PF13520.6 KXG46872.1 - 7e-54 183.3 41.9 8.9e-54 182.9 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG46872.1 - 7e-27 94.2 37.5 9.3e-27 93.7 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3309 PF11752.8 KXG46872.1 - 0.039 14.0 0.2 0.039 14.0 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3309) APH PF01636.23 KXG46874.1 - 4.3e-09 36.7 0.0 9.7e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG46874.1 - 0.00052 19.7 0.1 0.00091 18.9 0.1 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF3793 PF12672.7 KXG46874.1 - 0.17 12.0 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) ketoacyl-synt PF00109.26 KXG46875.1 - 3.4e-74 249.6 0.0 7.1e-74 248.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXG46875.1 - 3.3e-61 207.5 0.1 5.3e-61 206.9 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KXG46875.1 - 4.8e-49 166.7 0.0 1.3e-48 165.3 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KXG46875.1 - 1.3e-46 159.2 0.0 2.1e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KXG46875.1 - 1.9e-38 131.1 0.0 7e-38 129.3 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KXG46875.1 - 1.1e-18 67.8 0.0 2.8e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXG46875.1 - 3e-15 56.2 0.6 1.7e-14 53.8 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 KXG46875.1 - 6.8e-15 55.5 0.0 1.9e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KXG46875.1 - 2.3e-12 47.0 0.1 1.1e-11 44.8 0.1 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KXG46875.1 - 1e-11 45.4 0.0 4.3e-11 43.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KXG46875.1 - 2.4e-11 44.8 0.0 1.6e-09 38.9 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 KXG46875.1 - 1e-09 38.9 0.0 2.8e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG46875.1 - 1.2e-09 38.3 0.0 2.4e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KXG46875.1 - 7.7e-08 32.6 0.1 2.9e-07 30.7 0.1 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 KXG46875.1 - 9.5e-07 28.4 0.0 2.7e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 KXG46875.1 - 1.5e-06 27.9 0.0 4.6e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KXG46875.1 - 1.9e-06 27.5 0.1 4.6e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 KXG46875.1 - 4.8e-06 26.4 0.1 1.3e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.6 KXG46875.1 - 1.4e-05 25.0 0.0 7e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain SAT PF16073.5 KXG46875.1 - 0.0043 16.8 0.6 0.014 15.1 0.6 1.8 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Polysacc_synt_2 PF02719.15 KXG46875.1 - 0.022 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ACP_syn_III PF08545.10 KXG46875.1 - 0.043 13.7 1.3 0.61 10.0 1.3 2.6 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_24 PF13578.6 KXG46875.1 - 0.17 12.9 0.0 0.74 10.9 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain FSH1 PF03959.13 KXG46876.1 - 3.6e-29 102.0 0.0 7.5e-29 100.9 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXG46876.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase EMP24_GP25L PF01105.24 KXG46877.1 - 5.7e-49 166.5 0.8 6.6e-49 166.3 0.8 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Filament PF00038.21 KXG46878.1 - 0.0016 18.1 6.1 0.0016 18.1 6.1 4.7 1 1 3 4 4 4 2 Intermediate filament protein Fungal_trans_2 PF11951.8 KXG46879.1 - 6e-09 35.2 0.0 7.4e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_17 PF00332.18 KXG46880.1 - 2.9e-40 138.8 0.1 1.4e-39 136.5 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 GLE1 PF07817.13 KXG46881.1 - 2.1e-49 168.0 0.0 1.6e-48 165.1 0.0 2.1 1 1 0 1 1 1 1 GLE1-like protein Borrelia_P83 PF05262.11 KXG46881.1 - 0.02 13.4 31.0 0.026 13.0 31.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Ndc1_Nup PF09531.10 KXG46881.1 - 4 6.0 9.6 5.9 5.5 9.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RNB PF00773.19 KXG46882.1 - 4.5e-85 285.8 0.0 8.3e-85 285.0 0.0 1.5 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KXG46882.1 - 7.7e-26 89.9 0.0 1.8e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KXG46882.1 - 1.7e-25 89.1 0.0 4.6e-25 87.8 0.0 1.8 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 KXG46882.1 - 0.00019 21.5 0.0 0.019 15.1 0.0 2.7 2 0 0 2 2 2 1 Cold shock domain Rrp44_CSD1 PF17216.3 KXG46882.1 - 0.00025 20.8 0.0 0.00058 19.6 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain UQ_con PF00179.26 KXG46883.1 - 8.3e-36 122.7 0.0 1.5e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXG46883.1 - 0.0019 17.9 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF3736 PF12540.8 KXG46883.1 - 0.012 15.7 3.2 0.012 15.7 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3736) RWD PF05773.22 KXG46883.1 - 0.1 12.9 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 RWD domain PfkB PF00294.24 KXG46884.1 - 7.3e-70 235.7 0.0 8.2e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KXG46884.1 - 0.13 11.6 0.1 0.24 10.7 0.1 1.6 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase Apt1 PF10351.9 KXG46885.1 - 5.3 5.8 6.9 5.6 5.7 6.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain MMgT PF10270.9 KXG46886.1 - 8e-36 122.4 0.0 9.3e-36 122.2 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter EF1_GNE PF00736.19 KXG46887.1 - 1.2e-31 108.8 1.7 1.2e-31 108.8 1.7 1.9 1 1 1 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KXG46887.1 - 5.7e-12 45.9 2.6 5.7e-12 45.9 2.6 3.0 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 KXG46887.1 - 0.0001 22.5 0.6 0.00038 20.6 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXG46887.1 - 0.00013 22.1 0.2 0.00029 21.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXG46887.1 - 0.034 14.2 0.2 0.69 10.0 0.2 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA_2 PF07724.14 KXG46888.1 - 2.2e-46 158.1 0.0 6.3e-44 150.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KXG46888.1 - 1.2e-35 121.5 1.6 1.2e-35 121.5 1.6 2.5 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KXG46888.1 - 1e-26 92.8 0.3 3.2e-26 91.2 0.3 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KXG46888.1 - 3.1e-19 69.7 0.0 1.5e-10 41.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXG46888.1 - 1.2e-12 47.9 0.0 7.5e-08 32.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXG46888.1 - 7.2e-09 36.3 10.1 0.00027 21.3 0.4 4.6 3 2 0 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 KXG46888.1 - 8e-08 32.2 0.7 0.00026 20.7 0.0 2.5 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 KXG46888.1 - 9.9e-08 32.3 3.5 0.011 15.9 0.0 4.1 3 2 0 3 3 3 2 AAA domain TniB PF05621.11 KXG46888.1 - 1.8e-06 27.5 0.1 0.014 14.8 0.0 3.8 4 1 0 4 4 2 1 Bacterial TniB protein AAA_7 PF12775.7 KXG46888.1 - 1e-05 25.1 0.0 0.027 14.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 KXG46888.1 - 1.4e-05 25.1 0.1 0.18 11.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.6 KXG46888.1 - 1.9e-05 24.7 0.0 0.19 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KXG46888.1 - 9.5e-05 22.2 0.1 0.14 11.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 KXG46888.1 - 0.0001 22.3 5.6 2.9 7.8 0.0 4.5 4 2 2 6 6 4 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KXG46888.1 - 0.0001 22.1 0.0 0.64 9.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 KXG46888.1 - 0.00032 21.0 1.2 0.15 12.3 0.0 3.7 3 1 0 3 3 3 1 AAA domain SRP54 PF00448.22 KXG46888.1 - 0.00036 20.2 0.1 0.064 12.9 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KXG46888.1 - 0.001 19.6 0.9 0.79 10.3 0.0 3.2 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KXG46888.1 - 0.0013 19.1 0.0 0.86 10.0 0.0 2.8 2 1 0 2 2 2 1 RNA helicase AAA_19 PF13245.6 KXG46888.1 - 0.002 18.5 1.7 0.14 12.5 0.0 3.4 3 1 0 3 3 2 1 AAA domain AAA_30 PF13604.6 KXG46888.1 - 0.0021 17.8 0.8 0.18 11.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KXG46888.1 - 0.0021 17.5 0.1 3.3 7.0 0.0 3.1 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KXG46888.1 - 0.0027 17.7 0.1 2.8 8.0 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KXG46888.1 - 0.0039 17.1 0.1 3.5 7.5 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KXG46888.1 - 0.0062 16.3 0.0 0.24 11.1 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KXG46888.1 - 0.0072 16.8 2.0 2.3 8.7 0.0 3.3 3 0 0 3 3 3 1 ABC transporter ResIII PF04851.15 KXG46888.1 - 0.0076 16.3 0.0 4.3 7.3 0.0 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Roc PF08477.13 KXG46888.1 - 0.0079 16.4 0.1 1.2 9.3 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase UvrD-helicase PF00580.21 KXG46888.1 - 0.013 15.0 2.5 0.13 11.7 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain TrwB_AAD_bind PF10412.9 KXG46888.1 - 0.013 14.4 0.1 0.63 8.9 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.6 KXG46888.1 - 0.019 14.6 0.1 0.44 10.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KXG46888.1 - 0.022 13.9 0.3 0.62 9.2 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KXG46888.1 - 0.029 13.7 2.1 2.8 7.2 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin ATP_bind_1 PF03029.17 KXG46888.1 - 0.03 14.1 0.1 0.51 10.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KXG46888.1 - 0.033 14.1 0.1 0.53 10.2 0.0 2.6 2 0 0 2 2 2 0 NTPase PhoH PF02562.16 KXG46888.1 - 0.04 13.4 0.2 1 8.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 KXG46888.1 - 0.055 13.6 2.6 7 6.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_6 PF12774.7 KXG46888.1 - 0.1 11.5 0.0 4 6.3 0.0 2.5 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region cobW PF02492.19 KXG46888.1 - 0.11 12.1 0.0 12 5.4 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DNA_pol3_delta2 PF13177.6 KXG46888.1 - 0.11 12.3 0.2 3.6 7.4 0.0 2.8 2 1 0 2 2 2 0 DNA polymerase III, delta subunit AAA_29 PF13555.6 KXG46888.1 - 0.21 11.4 0.2 20 5.0 0.0 2.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 KXG46888.1 - 0.4 10.7 2.7 22 5.0 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_21 PF13304.6 KXG46888.1 - 0.75 9.6 3.8 3.7 7.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KXG46888.1 - 0.75 9.8 3.4 27 4.8 0.0 3.5 4 0 0 4 4 3 0 Helicase HerA, central domain DUF4349 PF14257.6 KXG46888.1 - 1.5 8.2 11.4 0.73 9.2 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) GAS PF13851.6 KXG46888.1 - 1.6 8.0 13.1 3.9 6.8 13.1 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding GrpE PF01025.19 KXG46888.1 - 2 8.0 10.8 7.6 6.2 10.8 2.1 1 0 0 1 1 1 0 GrpE V_ATPase_I PF01496.19 KXG46888.1 - 2.9 5.7 3.5 3.8 5.3 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OEP PF02321.18 KXG46888.1 - 3.9 7.2 12.5 8.6 6.1 12.5 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein UPF0242 PF06785.11 KXG46888.1 - 7 6.7 10.5 19 5.3 10.5 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 KXG46888.1 - 7.4 5.8 10.9 13 5.0 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 KXG46888.1 - 9.9 6.4 15.9 11 6.3 12.4 2.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MutS_V PF00488.21 KXG46889.1 - 4.4e-50 170.3 0.1 6.9e-50 169.7 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXG46889.1 - 8.9e-16 58.7 0.0 1.7e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 MutS domain III AAA PF00004.29 KXG46889.1 - 0.012 16.1 0.0 0.043 14.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2200 PF09966.9 KXG46889.1 - 0.035 14.2 0.1 0.097 12.8 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) T2SSE PF00437.20 KXG46889.1 - 0.058 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KXG46889.1 - 0.22 11.3 0.3 3.5 7.5 0.0 2.9 3 1 0 3 3 3 0 P-loop containing region of AAA domain Pkinase PF00069.25 KXG46890.1 - 2.2e-42 145.3 0.0 3.1e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG46890.1 - 5.6e-20 71.7 0.0 9.3e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG46890.1 - 0.0038 16.6 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXG46890.1 - 0.19 11.0 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sas10 PF09368.10 KXG46891.1 - 1.5e-27 95.8 10.7 1.5e-27 95.8 10.7 2.5 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KXG46891.1 - 1.5e-13 51.1 0.0 1.5e-13 51.1 0.0 2.9 3 1 0 3 3 3 1 Sas10/Utp3/C1D family adh_short PF00106.25 KXG46892.1 - 1.9e-26 92.7 0.0 2.8e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG46892.1 - 1.1e-14 54.6 0.0 2.1e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG46892.1 - 8.1e-08 32.4 0.1 1.7e-07 31.3 0.1 1.6 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXG46892.1 - 1.1e-05 25.0 0.1 4.8e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXG46892.1 - 0.00027 20.5 0.1 0.00064 19.3 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KXG46892.1 - 0.0045 17.0 0.0 0.0081 16.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 KXG46892.1 - 0.0052 16.1 0.2 0.0092 15.3 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_2 PF03446.15 KXG46892.1 - 0.02 15.1 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 KXG46892.1 - 0.04 14.4 0.0 0.064 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 KXG46892.1 - 0.049 12.9 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FA_hydroxylase PF04116.13 KXG46893.1 - 4.3e-18 65.9 6.3 4.3e-18 65.9 6.3 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L6e PF01159.19 KXG46894.1 - 4e-40 136.8 0.5 6.9e-40 136.1 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e AGP PF06376.12 KXG46894.1 - 0.016 15.1 0.2 0.14 12.0 0.3 2.3 2 0 0 2 2 2 0 Arabinogalactan peptide Proteasom_Rpn13 PF04683.13 KXG46895.1 - 1.3e-27 96.1 0.0 2.1e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KXG46895.1 - 4e-12 46.3 5.4 8.8e-11 42.0 5.4 2.4 1 1 0 1 1 1 1 UCH-binding domain Ion_trans PF00520.31 KXG46896.1 - 2.4e-125 416.7 86.6 8.3e-43 146.4 10.2 4.8 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 KXG46896.1 - 0.00019 21.1 0.0 0.00044 20.0 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 KXG46896.1 - 0.012 15.2 0.0 0.045 13.3 0.0 2.1 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KXG46896.1 - 0.13 12.3 0.0 0.67 10.0 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain SET PF00856.28 KXG46897.1 - 3.2e-16 60.2 0.2 6.7e-16 59.1 0.2 1.6 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 KXG46897.1 - 0.0017 19.0 0.1 0.0017 19.0 0.1 2.5 2 1 0 2 2 2 1 Pre-SET motif OPT PF03169.15 KXG46898.1 - 2.8e-146 488.7 50.6 1.7e-112 377.1 37.3 2.2 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Pkinase PF00069.25 KXG46898.1 - 3.4e-69 233.1 0.0 8.1e-69 231.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG46898.1 - 2.6e-39 135.1 0.0 4.8e-39 134.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KXG46898.1 - 1.1e-16 60.3 0.4 2e-16 59.5 0.4 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KXG46898.1 - 1.3e-05 24.3 0.0 2.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXG46898.1 - 2.5e-05 23.7 0.0 4.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXG46898.1 - 0.00014 21.2 0.0 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXG46898.1 - 0.0018 18.2 0.1 0.017 15.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 KXG46898.1 - 0.086 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) EIAV_GP90 PF00971.18 KXG46898.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 EIAV coat protein, gp90 RIO1 PF01163.22 KXG46898.1 - 0.15 11.7 0.1 0.37 10.4 0.1 1.6 1 1 0 1 1 1 0 RIO1 family DUF885 PF05960.11 KXG46899.1 - 2.1e-45 156.4 2.5 1.2e-44 153.9 2.5 1.9 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Nup54_C PF18437.1 KXG46899.1 - 0.029 14.3 0.9 10 6.1 0.2 2.9 2 0 0 2 2 2 0 Nup54 C-terminal interacting domain HMMR_N PF15905.5 KXG46899.1 - 0.053 13.0 2.8 0.096 12.1 2.8 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Grg1 PF11034.8 KXG46900.1 - 5e-29 100.3 15.1 5.7e-29 100.1 15.1 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 RSN1_7TM PF02714.15 KXG46901.1 - 8.5e-78 261.4 23.1 8.5e-78 261.4 23.1 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXG46901.1 - 5.9e-43 146.3 1.0 5.9e-43 146.3 1.0 2.8 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXG46901.1 - 1e-41 143.1 0.0 1.5e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter FSH1 PF03959.13 KXG46902.1 - 1.3e-56 191.7 0.0 1.5e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Esterase_phd PF10503.9 KXG46902.1 - 0.0034 16.9 0.0 0.0093 15.5 0.0 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KXG46902.1 - 0.031 13.5 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CLCA PF08434.11 KXG46903.1 - 0.081 12.2 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel N terminal RPE65 PF03055.15 KXG46904.1 - 6.7e-16 58.5 0.0 7.9e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF3445 PF11927.8 KXG46905.1 - 1e-79 267.3 0.0 1.3e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Homoserine_dh PF00742.19 KXG46906.1 - 4e-52 176.6 0.0 5.3e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KXG46906.1 - 8.7e-16 58.6 0.0 1.6e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXG46906.1 - 0.075 13.3 0.0 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF4078 PF13300.6 KXG46907.1 - 9.7e-28 96.3 9.8 9.7e-28 96.3 9.8 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) PRIMA1 PF16101.5 KXG46907.1 - 0.11 12.6 1.6 0.23 11.5 1.6 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 HMG_box PF00505.19 KXG46909.1 - 2e-25 89.0 0.5 2e-25 89.0 0.5 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXG46909.1 - 3.6e-18 65.9 2.4 3.7e-18 65.9 1.2 1.7 1 1 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KXG46909.1 - 0.014 16.0 0.0 0.014 16.0 0.0 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 YABBY PF04690.13 KXG46909.1 - 0.34 11.5 2.3 0.26 11.9 0.7 1.6 1 1 1 2 2 2 0 YABBY protein CENP-H PF05837.12 KXG46910.1 - 1.1e-29 103.2 13.1 1.3e-29 102.8 6.7 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) ATG11 PF10377.9 KXG46911.1 - 1.3e-45 154.6 0.1 1.3e-45 154.6 0.1 4.2 4 0 0 4 4 4 1 Autophagy-related protein 11 APG17 PF04108.12 KXG46911.1 - 3.4e-07 29.7 2.8 3.5e-05 23.1 1.5 5.3 3 2 2 5 5 5 2 Autophagy protein Apg17 ADIP PF11559.8 KXG46911.1 - 0.00072 19.7 4.4 0.00072 19.7 4.4 6.8 4 2 3 7 7 7 4 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 KXG46911.1 - 0.0035 17.8 11.1 0.0035 17.8 11.1 6.0 3 2 3 6 6 6 1 Fez1 ATG16 PF08614.11 KXG46911.1 - 0.0054 17.0 13.2 0.0054 17.0 13.2 6.7 3 2 3 6 6 6 2 Autophagy protein 16 (ATG16) ACP_PD PF04336.12 KXG46911.1 - 0.021 15.3 5.9 0.12 12.7 2.1 4.0 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase Bcr-Abl_Oligo PF09036.10 KXG46911.1 - 1.1 9.3 10.1 10 6.2 0.1 5.6 4 1 2 6 6 6 0 Bcr-Abl oncoprotein oligomerisation domain DUF948 PF06103.11 KXG46911.1 - 1.9 8.8 19.2 1.4 9.2 0.2 6.7 7 1 0 7 7 7 0 Bacterial protein of unknown function (DUF948) Abhydrolase_3 PF07859.13 KXG46914.1 - 4.7e-39 134.4 0.0 1.1e-37 130.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXG46914.1 - 1.2e-07 31.0 0.0 5e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 Steryl acetyl hydrolase HATPase_c PF02518.26 KXG46915.1 - 1.6e-30 105.9 0.0 4.5e-30 104.4 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXG46915.1 - 1.5e-19 70.2 0.0 6.8e-19 68.1 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KXG46915.1 - 1.5e-18 66.6 0.0 5e-18 64.9 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KXG46915.1 - 7.7e-14 52.2 0.0 2.5e-13 50.5 0.0 2.0 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.6 KXG46915.1 - 3.9e-10 40.4 0.0 3.3e-09 37.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain GAF PF01590.26 KXG46915.1 - 1.5e-08 35.3 0.0 3.9e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KXG46915.1 - 5.1e-06 26.9 0.0 1.7e-05 25.1 0.0 2.0 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KXG46915.1 - 3.9e-05 23.2 0.0 0.00021 20.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain HATPase_c_3 PF13589.6 KXG46915.1 - 0.00075 19.3 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NB-ARC PF00931.22 KXG46915.1 - 0.0008 18.7 2.1 0.67 9.1 0.7 3.0 3 0 0 3 3 3 2 NB-ARC domain DUF2514 PF10721.9 KXG46915.1 - 0.011 15.7 0.4 0.034 14.2 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) NACHT PF05729.12 KXG46915.1 - 0.038 13.9 0.7 0.76 9.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain TPR_8 PF13181.6 KXG46915.1 - 0.063 13.5 0.0 0.4 11.0 0.0 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_35 PF14516.6 KXG46915.1 - 0.099 11.5 0.0 0.31 9.8 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain Toprim PF01751.22 KXG46915.1 - 0.1 12.9 0.9 2.7 8.2 0.0 3.1 3 0 0 3 3 3 0 Toprim domain Sugar_tr PF00083.24 KXG46917.1 - 1.1e-58 199.2 29.9 1.4e-58 198.9 29.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG46917.1 - 6.5e-26 91.1 31.5 8.7e-26 90.7 31.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.6 KXG46918.1 - 6.3e-64 216.1 0.0 8.6e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_1 PF00232.18 KXG46919.1 - 5.9e-147 489.8 1.9 7.1e-147 489.5 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 AAT PF03417.16 KXG46920.1 - 5e-22 78.7 0.0 8.3e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Cytochrom_B561 PF03188.16 KXG46921.1 - 2.2e-16 60.2 4.0 2.2e-16 60.2 4.0 1.9 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KXG46921.1 - 0.061 13.5 14.1 1.3 9.1 5.6 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF3784 PF12650.7 KXG46921.1 - 0.46 10.7 4.5 2 8.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) GpcrRhopsn4 PF10192.9 KXG46921.1 - 0.5 9.7 6.2 0.23 10.8 0.8 2.4 1 1 1 3 3 3 0 Rhodopsin-like GPCR transmembrane domain DUF2427 PF10348.9 KXG46921.1 - 1.8 8.4 8.7 0.14 12.0 2.8 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF2834 PF11196.8 KXG46922.1 - 9 6.7 10.2 2.6 8.5 0.6 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2834) MFS_1 PF07690.16 KXG46923.1 - 9.6e-32 110.3 36.2 1.9e-31 109.3 36.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG46923.1 - 2e-09 36.9 27.5 5.4e-09 35.4 27.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Sec62 PF03839.16 KXG46923.1 - 1 8.8 3.4 3.2 7.2 3.4 1.8 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S24 PF00717.23 KXG46924.1 - 0.0019 18.1 0.1 0.0029 17.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like UQ_con PF00179.26 KXG46925.1 - 9.1e-41 138.8 0.0 1e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXG46925.1 - 7.2e-05 22.5 0.0 9.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXG46925.1 - 0.0077 16.5 0.0 0.0095 16.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KXG46925.1 - 0.085 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain F_bP_aldolase PF01116.20 KXG46927.1 - 2.3e-93 312.7 0.0 2.6e-93 312.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II UCH PF00443.29 KXG46928.1 - 1.3e-38 133.0 0.1 6.7e-34 117.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXG46928.1 - 1.4e-08 34.7 4.5 7e-07 29.1 4.5 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PSK_trans_fac PF07704.11 KXG46928.1 - 7.1 7.5 11.8 36 5.2 0.1 3.4 2 1 1 3 3 3 0 Rv0623-like transcription factor AlaDh_PNT_N PF05222.15 KXG46929.1 - 8.2e-30 103.9 0.0 1.3e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KXG46929.1 - 6.4e-05 22.3 0.0 0.0022 17.3 0.0 2.3 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain MRI PF15325.6 KXG46930.1 - 3.2 8.9 13.2 0.12 13.5 3.0 2.3 2 1 0 2 2 2 0 Modulator of retrovirus infection CUE PF02845.16 KXG46932.1 - 3e-08 33.2 0.0 4.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.8 KXG46932.1 - 0.0043 17.1 0.4 0.033 14.3 0.2 2.4 2 0 0 2 2 2 1 Ubiquitin-associated protein 2 Oxysterol_BP PF01237.18 KXG46933.1 - 4.8e-61 206.6 1.3 8.2e-59 199.3 1.3 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF3560 PF12083.8 KXG46933.1 - 0.02 15.0 0.3 0.038 14.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) BPS PF08947.10 KXG46933.1 - 0.34 10.8 1.3 0.61 9.9 0.8 1.7 2 0 0 2 2 2 0 BPS (Between PH and SH2) MFS_1 PF07690.16 KXG46934.1 - 9.6e-44 149.7 37.5 8e-43 146.7 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG46934.1 - 7e-09 35.1 10.6 7e-09 35.1 10.6 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KXG46934.1 - 2.7 6.2 7.6 0.82 7.9 2.7 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.8 KXG46935.1 - 4.1e-119 398.3 18.6 4.7e-119 398.1 18.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KXG46935.1 - 3.5e-08 32.8 11.7 3.5e-08 32.8 11.7 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4381 PF14316.6 KXG46935.1 - 0.16 12.3 2.4 0.37 11.0 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4381) COX16 PF14138.6 KXG46935.1 - 0.19 12.3 0.0 14 6.3 0.0 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Glyco_hydro_3 PF00933.21 KXG46936.1 - 3.2e-88 296.2 0.0 4.3e-88 295.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 KXG46936.1 - 3.3e-17 62.8 0.0 4.5e-10 39.8 0.0 2.7 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXG46936.1 - 1e-13 51.5 0.1 8.6e-08 32.5 0.0 2.8 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXG46936.1 - 1.3e-11 44.5 0.0 2.4e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KXG46936.1 - 0.0002 21.6 0.1 0.11 12.6 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.22 KXG46936.1 - 0.0016 18.4 0.0 0.0038 17.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_9 PF13527.7 KXG46936.1 - 0.0031 17.6 0.0 1.9 8.6 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXG46936.1 - 0.042 14.0 0.2 28 5.0 0.0 3.3 2 1 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 KXG46936.1 - 0.091 12.7 0.0 0.69 9.9 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein Sugar_tr PF00083.24 KXG46937.1 - 1.4e-91 307.6 19.6 1.8e-91 307.3 19.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG46937.1 - 1.4e-16 60.4 59.9 9.4e-14 51.1 26.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cwf_Cwc_15 PF04889.12 KXG46938.1 - 0.49 10.1 15.2 1.6 8.4 3.8 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RNase_T PF00929.24 KXG46939.1 - 6.9e-21 75.5 0.0 7.8e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 Exonuclease PGM_PMM_I PF02878.16 KXG46940.1 - 1.5e-31 109.0 0.1 2.2e-31 108.4 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KXG46940.1 - 1.4e-26 92.9 0.0 2.4e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KXG46940.1 - 9.6e-17 61.5 0.0 2.4e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KXG46940.1 - 2.2e-07 31.0 0.0 5.1e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GFO_IDH_MocA PF01408.22 KXG46941.1 - 2.7e-09 37.9 0.0 8.9e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXG46941.1 - 0.00042 20.3 0.0 0.0009 19.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sugar_tr PF00083.24 KXG46942.1 - 1.1e-80 271.7 21.3 1.7e-80 271.1 21.3 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG46942.1 - 8.3e-25 87.4 30.4 8.3e-25 87.4 30.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG46942.1 - 2.1e-05 23.5 7.4 2.1e-05 23.5 7.4 2.3 2 0 0 2 2 2 1 MFS_1 like family OATP PF03137.20 KXG46942.1 - 0.00086 17.7 3.0 0.51 8.6 0.0 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family K_oxygenase PF13434.6 KXG46943.1 - 2.2e-17 63.3 0.0 5.8e-12 45.4 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXG46943.1 - 2.7e-06 26.9 0.2 0.0087 15.3 0.0 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG46943.1 - 8.8e-06 25.8 0.0 0.23 11.4 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 KXG46943.1 - 1.9e-05 24.4 5.2 0.0026 17.4 0.2 3.6 3 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG46943.1 - 2.6e-05 23.6 0.0 0.18 11.0 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG46943.1 - 0.00057 19.1 0.0 0.024 13.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KXG46943.1 - 0.0019 17.5 0.0 0.012 14.8 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KXG46943.1 - 0.0019 17.3 0.0 0.0048 16.0 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 KXG46943.1 - 0.0042 15.8 0.0 0.095 11.4 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KXG46943.1 - 0.0049 16.0 0.0 0.34 9.9 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KXG46943.1 - 0.0067 16.6 1.7 0.15 12.3 0.0 3.4 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXG46943.1 - 0.0071 15.6 0.2 0.047 12.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 KXG46943.1 - 0.022 14.8 0.0 8.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF2798 PF11391.8 KXG46943.1 - 0.15 12.1 0.6 0.34 11.0 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) TrkA_N PF02254.18 KXG46943.1 - 0.21 11.9 0.0 0.65 10.3 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain SR-25 PF10500.9 KXG46943.1 - 0.25 10.9 10.5 0.043 13.4 4.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Glyco_hydro_18 PF00704.28 KXG46944.1 - 1.8e-45 156.0 6.6 2.8e-45 155.4 6.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KXG46944.1 - 2.8e-07 30.5 0.0 9.7e-05 22.4 0.0 2.8 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KXG46944.1 - 0.00013 22.4 7.7 0.00013 22.4 7.7 3.3 2 0 0 2 2 2 1 Chitin recognition protein Ank_3 PF13606.6 KXG46945.1 - 1.5e-05 25.0 0.6 2.4 9.0 0.0 5.7 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.6 KXG46945.1 - 5.9e-05 23.5 0.1 6.4 7.5 0.0 4.5 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXG46945.1 - 0.00015 22.3 0.0 0.07 13.7 0.0 3.8 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXG46945.1 - 0.0096 16.3 3.5 9 6.9 0.1 4.5 4 0 0 4 4 4 1 Ankyrin repeat LysM PF01476.20 KXG46946.1 - 2.4e-17 62.7 0.0 0.0055 16.7 0.0 6.0 6 0 0 6 6 6 4 LysM domain HTH_23 PF13384.6 KXG46946.1 - 0.0049 16.6 0.0 22 5.0 0.0 3.4 3 0 0 3 3 3 2 Homeodomain-like domain HTH_29 PF13551.6 KXG46946.1 - 0.078 13.0 0.0 26 4.9 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn helix HTH_28 PF13518.6 KXG46946.1 - 0.19 11.9 0.0 37 4.5 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain HMG_CoA_synt_C PF08540.10 KXG46948.1 - 1.6e-104 349.5 0.6 2.1e-104 349.1 0.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KXG46948.1 - 1e-96 321.8 0.3 1.9e-96 320.9 0.3 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal TFR_dimer PF04253.15 KXG46949.1 - 4.1e-36 123.7 0.1 7.7e-36 122.9 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KXG46949.1 - 3.6e-20 72.5 0.0 7.1e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXG46949.1 - 4e-12 46.0 0.0 7.5e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KXG46949.1 - 0.036 13.8 0.0 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KXG46949.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Fungal_trans PF04082.18 KXG46951.1 - 9.7e-05 21.5 0.0 0.00021 20.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ERAP1_C PF11838.8 KXG46951.1 - 0.003 17.1 0.0 0.0065 16.1 0.0 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain TPP_enzyme_N PF02776.18 KXG46952.1 - 3.4e-34 117.9 0.0 5.8e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXG46952.1 - 6.3e-19 68.1 0.0 2.3e-18 66.2 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KXG46952.1 - 1.9e-15 57.0 0.2 6.9e-14 51.9 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1765 PF08578.10 KXG46953.1 - 9e-46 155.4 7.3 1.2e-45 155.0 6.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) Ndc1_Nup PF09531.10 KXG46953.1 - 1.5 7.5 6.6 3 6.4 6.6 1.6 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ATP_sub_h PF10775.9 KXG46954.1 - 1.2e-24 86.1 3.1 1.2e-24 86.1 3.1 1.9 2 0 0 2 2 2 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 KXG46954.1 - 0.051 14.0 0.0 0.083 13.3 0.0 1.4 1 1 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 TFIIB PF00382.19 KXG46955.1 - 1.1e-39 134.2 0.2 8.9e-20 70.5 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KXG46955.1 - 6.5e-11 41.6 1.1 6.5e-11 41.6 1.1 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.23 KXG46955.1 - 0.00046 19.9 0.1 0.76 9.5 0.1 2.3 1 1 1 2 2 2 2 Cyclin, N-terminal domain RB_B PF01857.20 KXG46955.1 - 0.0028 17.7 0.0 0.0054 16.8 0.0 1.5 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 KXG46955.1 - 0.033 14.3 0.0 0.99 9.5 0.0 2.2 2 0 0 2 2 2 0 Cyclin, C-terminal domain TMIE PF16038.5 KXG46955.1 - 0.1 12.4 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 TMIE protein Sigma70_r4_2 PF08281.12 KXG46955.1 - 0.19 11.4 0.0 0.57 9.9 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4 PF04545.16 KXG46955.1 - 0.2 11.2 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 DUF1610 PF07754.11 KXG46955.1 - 0.36 10.9 2.6 1.2 9.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-ribbon_3 PF13248.6 KXG46955.1 - 6.3 6.3 8.1 6.2 6.4 3.5 2.6 2 1 0 2 2 2 0 zinc-ribbon domain Pannexin_like PF12534.8 KXG46956.1 - 0.062 12.4 0.2 0.071 12.2 0.2 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF4644 PF15486.6 KXG46956.1 - 0.1 12.3 1.7 0.13 12.0 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) Troponin-I_N PF11636.8 KXG46956.1 - 6.6 6.8 8.1 0.21 11.6 1.8 1.8 2 0 0 2 2 2 0 Troponin I residues 1-32 DIL PF01843.19 KXG46958.1 - 6.9e-30 103.4 1.5 6.9e-30 103.4 1.5 1.8 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.7 KXG46958.1 - 5.2e-14 52.6 0.0 1.9e-13 50.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG46958.1 - 2.5e-09 37.5 0.0 1.2e-05 25.7 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG46958.1 - 4.9e-09 36.3 0.0 0.002 18.4 0.0 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXG46958.1 - 4.5e-07 30.0 0.0 0.041 14.3 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KXG46958.1 - 5.6e-06 26.3 0.3 0.015 15.8 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat DUF3349 PF11829.8 KXG46958.1 - 0.0059 17.4 0.5 0.019 15.8 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3349) RasGEF PF00617.19 KXG46959.1 - 5.7e-43 147.2 0.6 1e-42 146.4 0.6 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXG46959.1 - 4.4e-13 49.4 1.2 1.1e-12 48.1 1.2 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Peptidase_M13_N PF05649.13 KXG46960.1 - 6.6e-94 315.7 0.0 9.9e-94 315.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KXG46960.1 - 2.3e-61 207.0 0.1 3.6e-61 206.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 FMN_dh PF01070.18 KXG46961.1 - 2.4e-81 273.5 0.0 2.9e-81 273.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXG46961.1 - 4.5e-07 29.3 0.0 1e-06 28.2 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXG46961.1 - 7.9e-07 28.4 0.1 2.1e-06 27.0 0.1 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KXG46961.1 - 0.00073 19.1 0.1 0.069 12.6 0.0 2.6 2 1 1 3 3 3 1 Histidine biosynthesis protein PHP PF02811.19 KXG46961.1 - 0.0015 18.9 0.0 1.3 9.3 0.0 2.2 2 0 0 2 2 2 2 PHP domain ThiG PF05690.14 KXG46961.1 - 0.04 13.2 0.2 4.2 6.6 0.0 2.8 2 1 0 3 3 3 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KXG46961.1 - 0.18 11.0 0.2 0.32 10.2 0.1 1.5 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DJ-1_PfpI PF01965.24 KXG46963.1 - 1.1e-12 48.1 0.0 1.1e-11 44.9 0.0 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KXG46963.1 - 0.0012 18.6 0.0 0.011 15.4 0.0 1.9 1 1 1 2 2 2 1 ThiJ/PfpI family-like GATase_3 PF07685.14 KXG46963.1 - 0.18 11.4 0.0 0.47 10.0 0.0 1.7 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain G-alpha PF00503.20 KXG46964.1 - 1.1e-108 363.5 0.3 1.3e-108 363.3 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KXG46964.1 - 5.2e-14 52.1 0.1 2.7e-09 36.7 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXG46964.1 - 9.9e-07 28.3 0.1 0.0012 18.2 0.1 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXG46964.1 - 0.0013 18.8 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase Roc PF08477.13 KXG46964.1 - 0.0037 17.5 0.0 0.81 9.9 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF1967 PF09269.11 KXG46964.1 - 0.0091 15.9 0.3 19 5.3 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1967) GTP_EFTU PF00009.27 KXG46964.1 - 0.061 12.9 0.0 4.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TniB PF05621.11 KXG46964.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 KXG46964.1 - 0.099 12.4 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KXG46964.1 - 0.12 12.7 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF1713 PF08213.11 KXG46965.1 - 6.7e-12 45.1 20.1 1.3e-11 44.2 20.1 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) ATP-synt_C PF00137.21 KXG46966.1 - 9.4e-36 122.0 32.2 6.1e-22 77.7 14.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.8 KXG46966.1 - 0.58 10.1 9.0 0.22 11.4 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) He_PIG_assoc PF10632.9 KXG46967.1 - 0.079 12.6 0.0 0.38 10.5 0.0 2.2 2 0 0 2 2 2 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase CFEM PF05730.11 KXG46968.1 - 0.00039 20.5 6.4 0.00086 19.3 6.4 1.6 1 0 0 1 1 1 1 CFEM domain Hydrolase_6 PF13344.6 KXG46970.1 - 2.9e-21 75.5 0.0 5.4e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXG46970.1 - 2.7e-13 49.8 0.0 1e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Lipase_3 PF01764.25 KXG46970.1 - 0.018 14.9 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase PF00702.26 KXG46970.1 - 0.18 12.1 0.0 20 5.3 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase tRNA-synt_2c PF01411.19 KXG46971.1 - 5.9e-10 38.3 0.0 7.6e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KXG46971.1 - 4.3e-08 33.1 0.6 7.7e-08 32.3 0.6 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain VirE2 PF07229.12 KXG46971.1 - 0.18 10.4 0.0 2.1 6.9 0.0 2.0 2 0 0 2 2 2 0 VirE2 DUF676 PF05057.14 KXG46972.1 - 3.5e-48 164.0 0.0 5.4e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KXG46972.1 - 7.5e-06 26.0 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KXG46972.1 - 1.3e-05 26.0 0.0 2.2e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KXG46972.1 - 5.9e-05 23.0 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KXG46972.1 - 0.00031 20.5 0.0 0.0018 18.1 0.0 2.1 2 1 0 2 2 2 1 PGAP1-like protein LCAT PF02450.15 KXG46972.1 - 0.021 14.0 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2235 PF09994.9 KXG46972.1 - 0.023 14.1 0.0 0.24 10.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Lipase_2 PF01674.18 KXG46972.1 - 0.068 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) DLH PF01738.18 KXG46972.1 - 0.08 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KXG46972.1 - 0.14 12.0 0.1 0.53 10.0 0.0 1.9 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase NAM-associated PF14303.6 KXG46973.1 - 1.3 9.7 7.4 2.3 8.9 7.4 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain PAT1 PF09770.9 KXG46973.1 - 6.7 4.8 6.4 9.1 4.4 6.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_L22e PF01776.17 KXG46974.1 - 8.3e-48 161.3 0.5 1e-47 161.0 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DIM1 PF02966.16 KXG46975.1 - 1e-70 235.7 0.1 1.1e-70 235.5 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KXG46975.1 - 0.067 13.2 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF3192 PF11399.8 KXG46975.1 - 0.13 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Translin PF01997.16 KXG46976.1 - 7.4e-50 169.8 0.0 8.6e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Translin family FRQ PF09421.10 KXG46976.1 - 0.056 11.5 0.1 0.073 11.1 0.1 1.1 1 0 0 1 1 1 0 Frequency clock protein GMP_synt_C PF00958.22 KXG46976.1 - 0.09 12.8 0.1 0.86 9.7 0.0 2.2 2 0 0 2 2 2 0 GMP synthase C terminal domain GSHPx PF00255.19 KXG46977.1 - 3.2e-38 129.6 0.0 4.6e-38 129.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KXG46977.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA family Ral PF11058.8 KXG46977.1 - 0.12 12.0 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral Exotox-A_target PF09102.10 KXG46978.1 - 0.27 11.2 2.4 12 5.9 0.3 2.2 2 0 0 2 2 2 0 Exotoxin A, targeting DSPn PF14671.6 KXG46979.1 - 3.4e-42 144.2 0.0 4.9e-40 137.2 0.0 2.5 2 0 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KXG46979.1 - 8.3e-17 61.2 0.1 7.6e-16 58.1 0.0 2.4 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXG46979.1 - 1.5e-05 24.7 0.1 4.5e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Ku_PK_bind PF08785.11 KXG46980.1 - 2.6e-38 130.9 0.0 5.3e-38 129.8 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 KXG46980.1 - 2.6e-34 118.7 0.0 4.8e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KXG46980.1 - 3.3e-11 43.3 0.0 6.8e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KXG46980.1 - 0.00042 20.6 2.3 0.00075 19.8 0.2 2.5 3 0 0 3 3 3 1 von Willebrand factor type A domain Ku_C PF03730.14 KXG46980.1 - 1.8 9.3 4.2 0.99 10.2 1.1 2.2 2 1 0 2 2 2 0 Ku70/Ku80 C-terminal arm DUF4149 PF13664.6 KXG46981.1 - 8e-29 100.0 2.3 8e-29 100.0 2.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 KXG46981.1 - 0.0053 17.1 0.4 0.0071 16.7 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Sugar_tr PF00083.24 KXG46982.1 - 7.1e-74 249.3 21.7 4.9e-72 243.2 18.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXG46982.1 - 7.3e-17 61.3 24.4 1e-16 60.8 24.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1700 PF08006.11 KXG46982.1 - 0.37 10.3 3.0 4.4 6.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Epimerase PF01370.21 KXG46983.1 - 6.3e-09 35.6 0.0 4.3e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXG46983.1 - 6.2e-08 32.5 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG46983.1 - 5.6e-07 29.6 0.1 1.3e-05 25.2 0.0 2.3 2 1 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXG46983.1 - 4.1e-05 22.7 0.0 9.9e-05 21.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXG46983.1 - 0.0024 17.1 0.1 0.007 15.6 0.0 1.7 2 1 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 KXG46983.1 - 0.015 15.8 0.0 0.032 14.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_23 PF13489.6 KXG46984.1 - 3.7e-21 75.7 0.0 5.8e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG46984.1 - 4.8e-11 42.7 0.0 5.2e-10 39.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG46984.1 - 9.7e-08 32.6 0.0 2.6e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG46984.1 - 6.5e-06 26.8 0.0 0.00015 22.5 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXG46984.1 - 0.001 18.6 0.0 0.014 14.9 0.0 2.5 2 1 1 3 3 3 1 Putative methyltransferase Methyltransf_11 PF08241.12 KXG46984.1 - 0.0013 19.4 0.0 0.0029 18.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXG46984.1 - 0.0018 17.8 0.0 0.0039 16.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 KXG46984.1 - 0.023 14.8 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KXG46984.1 - 0.028 14.1 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KXG46984.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KXG46984.1 - 0.12 11.7 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DAO PF01266.24 KXG46985.1 - 5.1e-26 92.1 0.1 6.7e-26 91.7 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXG46985.1 - 0.00064 20.2 1.4 0.0019 18.7 1.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG46985.1 - 0.0052 16.1 0.1 0.012 14.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG46985.1 - 0.045 13.0 0.5 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 KXG46985.1 - 0.059 12.6 0.3 0.12 11.7 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXG46985.1 - 0.2 11.2 0.5 0.37 10.4 0.5 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain BNR_2 PF13088.6 KXG46987.1 - 7e-06 25.6 0.0 2.7e-05 23.6 0.0 2.0 1 1 1 2 2 2 1 BNR repeat-like domain BNR_6 PF15899.5 KXG46987.1 - 0.00029 20.6 0.3 0.0014 18.5 0.2 2.3 2 0 0 2 2 2 1 BNR-Asp box repeat BNR PF02012.20 KXG46987.1 - 0.00068 19.3 5.3 0.091 12.8 0.1 4.0 4 0 0 4 4 4 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KXG46987.1 - 0.00089 18.2 0.2 0.14 10.9 0.0 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, PSII_BNR PF14870.6 KXG46987.1 - 0.083 12.1 0.9 10 5.3 0.0 3.0 2 1 1 4 4 4 0 Photosynthesis system II assembly factor YCF48 BNR_4 PF15892.5 KXG46987.1 - 0.19 11.0 1.9 4.8 6.5 0.1 2.4 2 0 0 2 2 2 0 BNR repeat-containing family member Aldo_ket_red PF00248.21 KXG46989.1 - 1.6e-31 109.6 0.0 2.8e-30 105.5 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.7 KXG46990.1 - 3.6e-05 23.6 0.2 9.4e-05 22.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXG46990.1 - 0.00042 20.1 0.2 0.0012 18.6 0.2 1.9 1 0 0 1 1 1 1 F-box domain Glyco_hydro_3_C PF01915.22 KXG46991.1 - 1.5e-54 185.1 0.0 2.3e-54 184.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXG46991.1 - 2e-40 139.1 0.1 2.7e-39 135.4 0.0 2.5 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXG46991.1 - 9.4e-17 60.9 0.1 2e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain bZIP_1 PF00170.21 KXG46992.1 - 0.0015 18.6 14.1 0.0025 17.9 10.4 2.3 1 1 1 2 2 2 1 bZIP transcription factor TACC_C PF05010.14 KXG46992.1 - 0.49 10.2 11.2 0.74 9.6 11.2 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HAUS-augmin3 PF14932.6 KXG46992.1 - 0.81 9.2 9.5 1.1 8.8 9.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 EBP PF05241.12 KXG46993.1 - 0.012 15.1 9.6 0.036 13.5 9.6 2.0 1 1 0 1 1 1 0 Emopamil binding protein TraD_N PF12615.8 KXG46993.1 - 0.012 16.4 0.6 0.032 15.0 0.6 1.7 1 0 0 1 1 1 0 F sex factor protein N terminal Fungal_trans PF04082.18 KXG46994.1 - 9.1e-26 90.5 0.0 2.6e-25 89.0 0.0 1.6 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG46994.1 - 2.9e-09 36.9 11.9 4.6e-09 36.2 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Man-6-P_recep PF02157.15 KXG46995.1 - 2.6e-15 56.2 0.0 3.6e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 KXG46995.1 - 1.2e-11 45.0 0.0 2.5e-11 43.9 0.0 1.5 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KXG46995.1 - 1e-06 28.9 0.1 0.0017 18.5 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ERG4_ERG24 PF01222.17 KXG46996.1 - 3.3e-157 523.7 4.4 3.7e-157 523.5 4.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KXG46996.1 - 0.0001 22.0 0.1 0.00027 20.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) A_deamin PF02137.18 KXG46997.1 - 0.00022 20.8 0.1 0.14 11.5 0.1 2.3 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain SF3b10 PF07189.11 KXG46998.1 - 7.3e-35 118.9 0.0 8.1e-35 118.8 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF3074 PF11274.8 KXG46999.1 - 9.2e-55 185.5 0.1 2.7e-54 184.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) START PF01852.19 KXG46999.1 - 0.0015 18.0 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 START domain Osmo_CC PF08946.10 KXG46999.1 - 0.076 13.3 2.4 12 6.2 0.7 3.2 3 0 0 3 3 3 0 Osmosensory transporter coiled coil SKA2 PF16740.5 KXG46999.1 - 5.9 6.7 12.7 2.2 8.1 5.5 2.8 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Seryl_tRNA_N PF02403.22 KXG46999.1 - 7.5 6.8 24.7 0.7 10.1 9.3 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Allexi_40kDa PF05549.11 KXG46999.1 - 7.6 5.9 18.4 0.52 9.8 4.1 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein YabA PF06156.13 KXG46999.1 - 8.8 7.0 11.7 0.44 11.2 2.5 2.9 2 1 0 2 2 2 0 Initiation control protein YabA PAH PF02671.21 KXG47001.1 - 0.00062 19.9 0.0 21 5.3 0.0 6.0 5 1 2 7 7 7 1 Paired amphipathic helix repeat SOG2 PF10428.9 KXG47001.1 - 0.044 13.0 10.4 0.071 12.3 10.4 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein NUC130_3NT PF08158.12 KXG47001.1 - 0.05 13.9 3.1 26 5.3 0.0 5.4 5 2 1 6 6 6 0 NUC130/3NT domain Ndc1_Nup PF09531.10 KXG47001.1 - 0.15 10.7 8.4 0.22 10.2 8.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S64 PF08192.11 KXG47001.1 - 0.35 9.3 7.2 0.46 8.9 7.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Apt1 PF10351.9 KXG47001.1 - 1.8 7.3 8.8 2.4 6.9 8.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain APG6_N PF17675.1 KXG47002.1 - 0.00061 20.3 1.4 0.00071 20.1 1.4 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region Phage_GP20 PF06810.11 KXG47002.1 - 0.022 14.6 7.3 0.028 14.2 7.3 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 UPF0242 PF06785.11 KXG47002.1 - 0.024 14.8 4.8 0.028 14.5 4.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ERM PF00769.19 KXG47002.1 - 0.04 13.7 13.0 0.053 13.3 13.0 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3552 PF12072.8 KXG47002.1 - 0.056 12.9 13.5 0.075 12.4 13.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) BRE1 PF08647.11 KXG47002.1 - 0.081 13.0 13.0 0.11 12.6 13.0 1.1 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase PRKCSH-like PF12999.7 KXG47002.1 - 0.091 12.6 3.4 0.12 12.2 3.4 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like ADIP PF11559.8 KXG47002.1 - 0.13 12.3 10.2 0.17 12.0 10.2 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CdvA PF18822.1 KXG47002.1 - 0.24 11.2 11.0 0.39 10.5 10.9 1.4 1 1 0 1 1 1 0 CdvA-like coiled-coil domain Golgin_A5 PF09787.9 KXG47002.1 - 0.25 10.8 11.5 0.31 10.4 11.5 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Chitin_synth_1N PF08407.11 KXG47002.1 - 0.26 11.3 3.8 0.29 11.1 0.4 2.4 1 1 2 3 3 3 0 Chitin synthase N-terminal NinG PF05766.12 KXG47002.1 - 0.26 11.2 5.9 0.31 11.0 5.9 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF2951 PF11166.8 KXG47002.1 - 0.69 10.2 6.0 0.93 9.7 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DUF4527 PF15030.6 KXG47002.1 - 0.93 8.9 9.3 0.56 9.6 4.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4527) Peptidase_S49_N PF08496.10 KXG47002.1 - 1.1 9.3 9.4 1.3 9.1 9.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4407 PF14362.6 KXG47002.1 - 1.1 8.5 6.1 1.4 8.2 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 KXG47002.1 - 1.9 7.7 8.5 2.2 7.4 8.5 1.0 1 0 0 1 1 1 0 TMPIT-like protein Agouti PF05039.12 KXG47002.1 - 2.7 8.7 5.1 4.1 8.2 5.1 1.4 1 1 0 1 1 1 0 Agouti protein SLS PF14611.6 KXG47003.1 - 7.5e-35 120.8 0.0 1.4e-34 119.9 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator NT-C2 PF10358.9 KXG47003.1 - 1.8e-31 108.8 0.0 3.9e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Myotub-related PF06602.14 KXG47004.1 - 9.1e-150 498.5 0.0 1.2e-149 498.1 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 KXG47004.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 GRAM domain Ribosomal_S3_C PF00189.20 KXG47005.1 - 9.6e-25 86.9 0.1 5e-24 84.6 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KXG47005.1 - 8.4e-12 44.8 0.0 1.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 KXG47005.1 - 0.1 13.1 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 KXG47005.1 - 0.13 12.1 0.1 0.32 10.8 0.0 1.6 2 0 0 2 2 2 0 Coilin N-terminus Glyco_transf_8 PF01501.20 KXG47006.1 - 8.1e-25 87.8 0.2 5.1e-24 85.2 0.2 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Abhydrolase_6 PF12697.7 KXG47006.1 - 8.1e-13 49.5 0.0 8.1e-13 49.5 0.0 4.3 3 2 1 4 4 4 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG47006.1 - 8.2e-12 45.3 0.0 5.7e-11 42.6 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Nucleotid_trans PF03407.16 KXG47006.1 - 6.6e-05 23.0 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Hydrolase_4 PF12146.8 KXG47006.1 - 0.0054 16.0 0.0 0.0095 15.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Prok-E2_E PF14462.6 KXG47006.1 - 1.9 8.3 4.3 0.63 9.9 0.1 2.3 3 0 0 3 3 3 0 Prokaryotic E2 family E Glyco_transf_90 PF05686.12 KXG47007.1 - 1.8e-18 66.6 9.6 1.2e-15 57.4 7.1 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ferric_reduct PF01794.19 KXG47007.1 - 2.1e-14 53.7 3.6 5.2e-14 52.4 3.6 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component DUF2678 PF10856.8 KXG47007.1 - 0.044 13.7 0.3 0.094 12.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) CoatB PF10389.9 KXG47007.1 - 0.077 12.8 2.8 0.1 12.5 0.7 2.3 2 0 0 2 2 2 0 Bacteriophage coat protein B Cyt_bd_oxida_II PF02322.15 KXG47007.1 - 1.1 8.6 8.3 0.27 10.5 5.2 1.5 1 1 1 2 2 2 0 Cytochrome bd terminal oxidase subunit II HEAT PF02985.22 KXG47008.1 - 8.7e-39 128.2 10.9 0.015 15.5 0.1 13.2 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.6 KXG47008.1 - 1.1e-35 121.9 6.4 3.7e-11 43.3 0.0 7.8 4 2 5 9 9 9 8 HEAT repeats HEAT_EZ PF13513.6 KXG47008.1 - 1.6e-13 50.8 8.9 0.00098 19.6 0.0 8.9 6 3 4 10 10 10 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KXG47008.1 - 9.8e-12 45.3 2.7 0.0015 19.1 0.1 7.4 5 2 4 9 9 9 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KXG47008.1 - 2.4e-09 37.4 11.1 0.011 15.7 0.2 5.5 4 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KXG47008.1 - 2.4e-07 29.7 10.0 1.6e-05 23.7 2.7 4.3 2 1 1 4 4 4 3 Adaptin N terminal region RTP1_C1 PF10363.9 KXG47008.1 - 2.5e-06 27.6 6.7 0.27 11.4 0.2 5.0 4 1 1 5 5 5 3 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KXG47008.1 - 0.00086 18.9 2.0 0.31 10.6 0.1 4.3 3 2 2 5 5 5 1 CLASP N terminal Proteasom_PSMB PF10508.9 KXG47008.1 - 0.0035 15.9 3.4 0.53 8.7 0.1 2.6 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit TetR_C_16 PF17920.1 KXG47008.1 - 0.042 14.1 0.3 22 5.3 0.1 3.3 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain IFRD PF05004.13 KXG47008.1 - 0.25 10.4 1.5 2.7 7.0 0.0 3.3 3 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) Arm PF00514.23 KXG47008.1 - 0.45 10.6 9.6 3.7 7.7 0.0 5.7 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat tRNA_synthFbeta PF17759.1 KXG47009.1 - 3.5e-49 167.2 0.0 5.4e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KXG47009.1 - 2e-34 117.7 0.2 6.2e-33 112.9 0.1 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KXG47009.1 - 1.1e-24 87.0 0.1 2.4e-24 85.9 0.1 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KXG47009.1 - 1.2e-19 70.4 0.0 5.6e-17 61.8 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain CDO_I PF05995.12 KXG47010.1 - 4.7e-42 143.2 0.0 6e-42 142.8 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KXG47010.1 - 0.001 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO MMR_HSR1_Xtn PF16897.5 KXG47011.1 - 7.1e-39 132.1 1.1 3.3e-38 130.0 0.3 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KXG47011.1 - 2.1e-22 79.4 0.2 5.8e-22 77.9 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KXG47011.1 - 7.7e-20 70.7 0.0 1.8e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KXG47011.1 - 7.9e-11 41.7 0.1 3.5e-10 39.6 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXG47011.1 - 2.1e-05 24.6 0.1 0.15 12.1 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KXG47011.1 - 0.00061 19.4 0.2 15 5.1 0.0 4.0 2 2 2 4 4 4 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXG47011.1 - 0.0029 17.5 0.7 0.26 11.2 0.0 3.1 2 1 1 3 3 3 1 RsgA GTPase AIG1 PF04548.16 KXG47011.1 - 0.0089 15.4 0.1 0.014 14.7 0.1 1.2 1 0 0 1 1 1 1 AIG1 family MeaB PF03308.16 KXG47011.1 - 0.0099 14.9 0.2 0.024 13.6 0.1 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 KXG47011.1 - 0.04 13.4 0.3 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family HTH_Tnp_Tc5 PF03221.16 KXG47012.1 - 1.3e-14 53.9 0.0 2.5e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KXG47012.1 - 5.6e-05 22.7 0.1 0.00012 21.7 0.1 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 KXG47012.1 - 0.0005 19.8 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 KXG47012.1 - 0.017 15.0 0.1 0.098 12.6 0.0 2.2 2 0 0 2 2 2 0 MarR family HTH_Tnp_4 PF13613.6 KXG47012.1 - 0.036 13.8 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_10 PF04967.12 KXG47012.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Crp_2 PF13545.6 KXG47012.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 KXG47012.1 - 0.19 11.5 1.1 8.3 6.3 0.0 2.9 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_37 PF13744.6 KXG47012.1 - 0.2 11.7 0.0 4.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain PXA PF02194.15 KXG47013.1 - 1.7e-48 165.0 0.0 3.5e-48 164.0 0.0 1.6 1 0 0 1 1 1 1 PXA domain IU_nuc_hydro PF01156.19 KXG47014.1 - 1e-83 281.4 0.0 1.2e-83 281.2 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Vac_ImportDeg PF09783.9 KXG47015.1 - 3.9e-40 137.3 0.0 1.3e-39 135.6 0.0 1.7 2 0 0 2 2 2 1 Vacuolar import and degradation protein Amino_oxidase PF01593.24 KXG47016.1 - 2.1e-69 235.0 0.1 2.5e-67 228.1 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXG47016.1 - 2.3e-08 34.1 0.1 6.5e-08 32.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXG47016.1 - 8.2e-05 23.1 0.1 0.099 13.2 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG47016.1 - 0.00012 21.4 0.0 0.014 14.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG47016.1 - 0.001 18.4 0.3 0.047 12.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG47016.1 - 0.0036 16.9 1.1 0.036 13.7 0.2 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXG47016.1 - 0.0081 15.4 0.1 0.014 14.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KXG47016.1 - 0.013 15.5 0.0 5.5 7.0 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KXG47016.1 - 0.017 14.4 1.1 0.027 13.8 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KXG47016.1 - 0.043 13.1 0.7 0.074 12.3 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 KXG47016.1 - 0.095 12.0 0.2 0.29 10.4 0.3 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KXG47016.1 - 0.24 10.4 0.1 0.5 9.4 0.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A MFS_1 PF07690.16 KXG47017.1 - 3.9e-37 128.0 29.2 4.5e-37 127.8 29.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG47017.1 - 2e-09 36.9 16.1 4.2e-09 35.8 15.9 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Zn_clus PF00172.18 KXG47018.1 - 3.7e-10 39.7 12.5 6.5e-10 39.0 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NMO PF03060.15 KXG47019.1 - 3e-35 122.2 9.8 2e-28 99.7 5.3 2.1 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KXG47019.1 - 8.7e-08 31.5 1.3 1.8e-07 30.5 1.3 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXG47019.1 - 1.4e-06 27.6 1.5 2e-06 27.1 1.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXG47019.1 - 2.6e-06 26.8 0.5 4.8e-06 26.0 0.4 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase p450 PF00067.22 KXG47021.1 - 2.9e-46 158.2 0.0 4.3e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L7Ae PF01248.26 KXG47022.1 - 7.1e-27 93.0 0.6 8.8e-27 92.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KXG47022.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Ank_2 PF12796.7 KXG47023.1 - 8.2e-23 80.8 0.2 2.3e-12 47.3 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG47023.1 - 2.5e-17 63.0 0.2 4.3e-07 30.4 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG47023.1 - 3.8e-17 62.1 0.8 4.1e-08 33.3 0.0 5.0 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 KXG47023.1 - 3.4e-13 49.4 2.0 0.003 18.0 0.0 5.8 6 0 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.6 KXG47023.1 - 8.2e-12 44.2 0.3 0.003 17.9 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Steroid_dh PF02544.16 KXG47024.1 - 5.7e-12 45.8 0.5 5.7e-12 45.8 0.5 2.0 2 1 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase BRI3BP PF14965.6 KXG47024.1 - 0.00055 19.5 0.7 0.00055 19.5 0.7 2.6 3 0 0 3 3 3 1 Negative regulator of p53/TP53 YbgT_YccB PF08173.11 KXG47024.1 - 2.7 8.2 8.7 7.6 6.8 8.7 1.9 1 0 0 1 1 1 0 Membrane bound YbgT-like protein 2OG-FeII_Oxy_2 PF13532.6 KXG47025.1 - 1.2e-13 51.7 0.0 2.2e-12 47.6 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KXG47025.1 - 0.035 14.6 0.1 0.079 13.4 0.1 1.7 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily Rotamase_3 PF13616.6 KXG47026.1 - 1.9e-16 60.6 1.6 3.7e-16 59.7 0.3 2.0 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase PF00639.21 KXG47026.1 - 2.5e-14 54.0 0.4 5.2e-14 53.0 0.0 1.6 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KXG47026.1 - 7.3e-06 26.8 3.9 1.7e-05 25.6 0.0 2.0 1 1 1 2 2 2 1 PPIC-type PPIASE domain UAA PF08449.11 KXG47027.1 - 2.9e-43 148.2 8.3 5.9e-43 147.2 8.3 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXG47027.1 - 1.5e-07 31.7 26.5 4.6e-05 23.6 8.1 3.5 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KXG47027.1 - 8.3e-06 25.2 1.2 0.049 12.8 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter DUF5090 PF17009.5 KXG47027.1 - 1.7 8.6 7.1 0.38 10.7 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) Sen15 PF09631.10 KXG47028.1 - 1.4e-12 47.8 0.0 5.6e-11 42.6 0.0 2.3 1 1 0 1 1 1 1 Sen15 protein VASt PF16016.5 KXG47029.1 - 4.1e-34 118.2 0.1 1e-33 116.9 0.1 1.7 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 KXG47029.1 - 3.1e-15 56.6 0.1 7.3e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KXG47029.1 - 3.6e-10 40.3 0.0 1.5e-09 38.3 0.0 2.2 1 0 0 1 1 1 1 PH domain BAR PF03114.18 KXG47029.1 - 0.0063 16.2 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 BAR domain GRAM PF02893.20 KXG47029.1 - 0.012 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 GRAM domain Kri1_C PF12936.7 KXG47030.1 - 6.6e-32 109.6 1.0 6.6e-32 109.6 1.0 3.6 3 1 0 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.12 KXG47030.1 - 6.3e-29 100.6 15.3 6.3e-29 100.6 15.3 5.3 6 1 0 6 6 6 1 KRI1-like family LicD PF04991.13 KXG47030.1 - 0.0013 19.0 2.1 0.0013 19.0 2.1 2.6 2 1 0 2 2 2 1 LicD family TMPIT PF07851.13 KXG47030.1 - 3.6 6.7 7.3 0.79 8.9 3.4 1.8 2 0 0 2 2 2 0 TMPIT-like protein Mito_carr PF00153.27 KXG47031.1 - 2.7e-67 222.7 6.1 1.6e-24 85.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_88 PF07470.13 KXG47031.1 - 0.069 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 Stb3 PF10330.9 KXG47033.1 - 1.3e-39 134.1 0.0 2e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein COesterase PF00135.28 KXG47034.1 - 1.2e-70 238.9 0.2 5.6e-70 236.7 0.2 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG47034.1 - 4e-12 46.4 0.2 3.3e-11 43.5 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXG47034.1 - 0.00017 21.1 0.1 0.00024 20.7 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ribosomal_S19e PF01090.19 KXG47036.1 - 6.6e-56 187.8 0.1 1.3e-55 186.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_6 PF12697.7 KXG47036.1 - 2.3e-17 64.3 3.0 6.8e-17 62.8 1.3 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG47036.1 - 1.4e-15 57.6 0.0 4.5e-15 56.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG47036.1 - 1e-11 44.6 0.1 7.6e-09 35.2 0.0 3.0 3 0 0 3 3 3 2 Serine aminopeptidase, S33 DSPc PF00782.20 KXG47036.1 - 1.6e-09 37.7 0.0 3.5e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 KXG47036.1 - 0.00011 22.4 0.1 0.0002 21.6 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 KXG47036.1 - 0.00048 20.0 0.6 0.0036 17.2 0.0 2.4 3 0 0 3 3 3 1 Serine hydrolase Lipase_3 PF01764.25 KXG47036.1 - 0.00048 20.0 0.2 0.0047 16.8 0.1 2.2 1 1 1 2 2 2 1 Lipase (class 3) DUF1749 PF08538.10 KXG47036.1 - 0.0015 17.7 0.0 0.066 12.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) PGAP1 PF07819.13 KXG47036.1 - 0.0048 16.7 0.0 0.073 12.8 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Y_phosphatase PF00102.27 KXG47036.1 - 0.031 13.9 0.0 0.097 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein-tyrosine phosphatase LIDHydrolase PF10230.9 KXG47036.1 - 0.053 13.1 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase LCAT PF02450.15 KXG47036.1 - 0.16 11.1 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Chlorophyllase2 PF12740.7 KXG47036.1 - 0.18 10.7 0.0 0.36 9.7 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme ILVD_EDD PF00920.21 KXG47037.1 - 4.3e-212 705.3 0.7 5e-212 705.1 0.7 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1772 PF08592.11 KXG47038.1 - 1.6e-28 99.8 0.0 2e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Pex2_Pex12 PF04757.14 KXG47039.1 - 3.9e-37 128.0 0.2 5.6e-37 127.5 0.2 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KXG47039.1 - 0.0016 18.6 5.3 0.0031 17.6 5.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KXG47039.1 - 0.13 12.2 1.6 0.29 11.1 1.6 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXG47039.1 - 0.15 12.1 3.4 0.5 10.4 3.4 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Aldedh PF00171.22 KXG47040.1 - 6.1e-162 539.3 0.3 6.9e-162 539.1 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXG47040.1 - 7.5e-05 22.3 0.2 0.0009 18.8 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Longin_2 PF18639.1 KXG47040.1 - 0.089 12.7 0.0 1.8 8.4 0.0 2.5 3 0 0 3 3 3 0 Yeast longin domain F-box-like PF12937.7 KXG47041.1 - 0.033 14.1 0.1 0.074 13.0 0.1 1.6 1 0 0 1 1 1 0 F-box-like Phosphoesterase PF04185.14 KXG47042.1 - 2.1e-33 116.0 5.5 1.6e-32 113.1 5.5 2.1 1 1 0 1 1 1 1 Phosphoesterase family HIF-1a_CTAD PF08778.10 KXG47042.1 - 0.076 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain IBN_N PF03810.19 KXG47044.1 - 1.7e-15 56.7 0.0 1.3e-14 53.9 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KXG47044.1 - 5.5e-05 23.3 2.1 0.00029 20.9 0.0 3.0 3 1 0 3 3 3 1 Exportin 1-like protein Cellulase PF00150.18 KXG47045.1 - 1.3e-18 67.5 3.2 4.7e-18 65.6 3.2 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CN_hydrolase PF00795.22 KXG47046.1 - 3e-37 128.4 0.0 3.5e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_2_C PF02836.17 KXG47047.1 - 3.4e-14 52.6 0.0 1.9e-13 50.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 KXG47047.1 - 1.3e-13 51.6 0.2 1.3e-13 51.6 0.2 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KXG47047.1 - 3.3e-13 49.9 0.1 1.3e-12 47.9 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain BetaGal_dom4_5 PF13364.6 KXG47047.1 - 0.00021 21.8 0.4 0.45 11.1 0.0 2.5 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain Protoglobin PF11563.8 KXG47048.1 - 4e-56 189.3 0.4 4.9e-56 189.0 0.4 1.1 1 0 0 1 1 1 1 Protoglobin Aldedh PF00171.22 KXG47049.1 - 6.5e-137 456.8 0.4 7.5e-137 456.6 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GPI-anchored PF10342.9 KXG47050.1 - 5.5e-24 84.7 0.1 5.5e-24 84.7 0.1 2.3 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Fungal_trans PF04082.18 KXG47051.1 - 2.4e-11 43.2 0.3 3.5e-11 42.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mod_r PF07200.13 KXG47051.1 - 0.11 12.6 0.6 0.21 11.7 0.6 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein adh_short PF00106.25 KXG47052.1 - 4e-31 108.0 0.0 7.6e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG47052.1 - 6.4e-18 65.2 0.0 1.1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.18 KXG47052.1 - 1.2e-12 47.4 0.8 2.3e-12 46.5 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain KR PF08659.10 KXG47052.1 - 1.1e-06 28.7 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KR domain UPF0449 PF15136.6 KXG47053.1 - 0.038 14.4 2.0 0.038 14.4 2.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Remorin_C PF03763.13 KXG47053.1 - 0.26 11.2 5.8 0.43 10.5 5.8 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region bZIP_2 PF07716.15 KXG47053.1 - 0.66 10.1 13.0 0.51 10.5 11.7 1.5 1 1 0 1 1 1 0 Basic region leucine zipper SGL PF08450.12 KXG47054.1 - 4.4e-72 242.6 0.0 5.2e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Aldedh PF00171.22 KXG47055.1 - 8.6e-183 608.1 0.2 9.7e-183 607.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXG47055.1 - 0.00059 19.3 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) DUF5133 PF17196.4 KXG47055.1 - 0.28 11.4 2.6 5 7.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) EVE PF01878.18 KXG47056.1 - 1.7e-49 167.6 0.3 2.6e-49 166.9 0.3 1.3 1 0 0 1 1 1 1 EVE domain AT_hook PF02178.19 KXG47056.1 - 2.7e-09 35.8 47.5 0.03 14.2 2.0 5.9 5 0 0 5 5 5 5 AT hook motif AhpC-TSA PF00578.21 KXG47057.1 - 4.4e-23 81.5 0.0 7.7e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 KXG47057.1 - 5.9e-14 51.6 0.2 1e-13 50.9 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 KXG47057.1 - 5.2e-08 32.7 0.0 7.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin GidB PF02527.15 KXG47057.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Kelch_4 PF13418.6 KXG47058.1 - 1.1e-18 66.9 0.1 4.2e-06 26.7 0.0 5.2 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KXG47058.1 - 1.7e-14 53.6 3.5 4.7e-09 36.3 0.0 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KXG47058.1 - 1.3e-13 50.6 0.2 8.2e-05 22.5 0.0 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 KXG47058.1 - 3.7e-12 45.6 0.2 0.0034 16.9 0.0 4.3 4 1 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 KXG47058.1 - 1.1e-11 44.5 4.5 0.015 15.6 0.0 5.4 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KXG47058.1 - 6.1e-11 41.8 0.1 0.001 19.0 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Ribophorin_II PF05817.14 KXG47061.1 - 1.1e-30 106.8 0.0 1.5e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II ORC6 PF05460.13 KXG47062.1 - 0.56 9.4 6.0 0.61 9.3 6.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FMN_bind_2 PF04299.12 KXG47063.1 - 1.9e-59 200.1 0.0 2.3e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Sulfatase PF00884.23 KXG47064.1 - 7.4e-20 71.6 1.6 1.3e-19 70.7 1.6 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXG47064.1 - 1e-07 31.9 0.1 1.8e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KXG47064.1 - 2.9e-05 22.9 0.0 4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Dam PF05869.11 KXG47064.1 - 0.047 13.3 0.3 0.11 12.1 0.3 1.5 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) DUF1501 PF07394.12 KXG47064.1 - 0.086 11.9 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) adh_short_C2 PF13561.6 KXG47065.1 - 1.6e-57 194.8 0.3 1.8e-57 194.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG47065.1 - 6.1e-48 162.9 0.9 7.2e-48 162.6 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG47065.1 - 3.1e-15 56.6 0.4 4.1e-15 56.2 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXG47065.1 - 2.9e-05 23.6 0.1 4e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG47065.1 - 0.0045 16.4 0.4 0.012 15.0 0.0 1.8 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase HNH_repeat PF18780.1 KXG47065.1 - 0.2 11.5 1.7 0.52 10.2 1.7 1.7 1 0 0 1 1 1 0 Homing endonuclease repeat PTR2 PF00854.21 KXG47066.1 - 0.075 11.9 0.0 0.085 11.7 0.0 1.1 1 0 0 1 1 1 0 POT family PLA2_B PF01735.18 KXG47067.1 - 2.2e-207 689.3 2.2 2.9e-207 689.0 2.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF5583 PF17821.1 KXG47068.1 - 0.095 12.7 0.1 0.46 10.4 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5583) BRCT PF00533.26 KXG47068.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DAHP_synth_2 PF01474.16 KXG47069.1 - 1.1e-199 663.5 0.0 1.2e-199 663.4 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family SPX PF03105.19 KXG47070.1 - 4.9 7.0 6.9 5.8 6.7 6.9 1.1 1 0 0 1 1 1 0 SPX domain Sporozoite_P67 PF05642.11 KXG47070.1 - 5.1 5.1 16.4 6.3 4.7 16.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PAP1 PF08601.10 KXG47070.1 - 5.5 6.6 13.8 5.9 6.5 13.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 MFS_1 PF07690.16 KXG47071.1 - 1.1e-11 44.3 31.0 4.8e-09 35.6 5.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily UBA_4 PF14555.6 KXG47072.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain AA_permease_2 PF13520.6 KXG47074.1 - 7.2e-47 160.2 47.8 8.5e-47 159.9 47.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG47074.1 - 1.4e-16 60.2 39.5 2.1e-16 59.6 39.5 1.1 1 0 0 1 1 1 1 Amino acid permease Aldose_epim PF01263.20 KXG47075.1 - 1.4e-40 139.5 0.1 1.9e-40 139.0 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF756 PF05506.12 KXG47075.1 - 0.12 13.3 0.0 17 6.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF756) TBSV_P22 PF03558.13 KXG47075.1 - 0.14 11.7 0.0 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 TBSV core protein P21/P22 SNF PF00209.18 KXG47076.1 - 8.4e-73 245.8 38.4 4.4e-46 157.7 17.0 2.8 3 0 0 3 3 3 2 Sodium:neurotransmitter symporter family DUF3810 PF12725.7 KXG47076.1 - 0.03 13.7 1.0 0.072 12.4 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Aldo_ket_red PF00248.21 KXG47077.1 - 3.7e-48 164.2 0.0 4.2e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Rif1_N PF12231.8 KXG47078.1 - 1.5e-143 478.4 0.3 2.1e-143 477.8 0.3 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.9 KXG47079.1 - 5.3e-116 388.4 0.0 6.6e-116 388.1 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Cnd3 PF12719.7 KXG47079.1 - 0.0014 17.9 0.0 0.0029 16.8 0.0 1.5 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain WAPL PF07814.13 KXG47079.1 - 0.059 12.2 0.0 0.97 8.1 0.0 2.6 2 1 1 3 3 3 0 Wings apart-like protein regulation of heterochromatin Polysacc_synt_4 PF04669.13 KXG47080.1 - 8.4e-19 67.9 1.3 3.4e-17 62.6 1.3 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis ABC_membrane PF00664.23 KXG47081.1 - 8.6e-84 281.4 26.4 2.3e-42 145.5 9.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXG47081.1 - 1.2e-61 207.2 0.5 3.4e-29 102.1 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KXG47081.1 - 2.8e-18 66.2 0.1 5.9e-08 32.4 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Abhydrolase_6 PF12697.7 KXG47081.1 - 5.1e-13 50.1 2.8 1e-12 49.2 1.9 2.1 2 0 0 2 2 1 1 Alpha/beta hydrolase family AAA_21 PF13304.6 KXG47081.1 - 2.9e-12 47.0 1.3 0.16 11.8 0.0 4.5 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXG47081.1 - 1.6e-08 34.2 0.3 0.0074 16.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXG47081.1 - 8e-07 29.4 0.4 0.019 15.2 0.1 3.5 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KXG47081.1 - 1.7e-06 28.5 0.3 0.093 13.1 0.2 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KXG47081.1 - 2.7e-06 27.1 0.0 0.25 10.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KXG47081.1 - 6.3e-06 26.2 0.2 0.16 11.9 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_15 PF13175.6 KXG47081.1 - 5.7e-05 23.0 1.1 0.14 11.8 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 KXG47081.1 - 0.00065 19.9 0.6 0.65 10.1 0.1 2.9 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 KXG47081.1 - 0.0011 19.5 0.1 0.65 10.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KXG47081.1 - 0.0013 18.9 1.5 1.2 9.1 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_5 PF07728.14 KXG47081.1 - 0.0016 18.5 0.1 2.1 8.3 0.1 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KXG47081.1 - 0.0035 17.9 0.2 0.61 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KXG47081.1 - 0.0046 17.0 0.7 2.1 8.4 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 KXG47081.1 - 0.0085 16.5 0.0 0.3 11.5 0.0 3.3 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 KXG47081.1 - 0.011 14.6 0.8 0.49 9.1 0.1 3.0 4 0 0 4 4 4 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 KXG47081.1 - 0.012 15.4 0.2 31 4.2 0.0 4.1 4 0 0 4 4 4 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KXG47081.1 - 0.015 15.7 0.1 3.9 7.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.20 KXG47081.1 - 0.021 14.7 0.1 7.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase SbcCD_C PF13558.6 KXG47081.1 - 0.021 15.1 0.0 13 6.1 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF3987 PF13148.6 KXG47081.1 - 0.026 13.6 0.2 6.4 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) SAM35 PF10806.8 KXG47081.1 - 0.029 14.6 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 SAM35, subunit of SAM coomplex NACHT PF05729.12 KXG47081.1 - 0.038 13.9 1.5 3 7.7 0.1 2.9 3 0 0 3 3 2 0 NACHT domain CbiA PF01656.23 KXG47081.1 - 0.055 13.5 0.3 4.3 7.4 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KXG47081.1 - 0.067 12.9 0.4 8 6.1 0.0 3.3 4 0 0 4 4 4 0 AAA domain Sigma54_activat PF00158.26 KXG47081.1 - 0.073 12.8 0.0 13 5.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_10 PF12846.7 KXG47081.1 - 0.096 11.6 0.0 3.4 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.18 KXG47081.1 - 0.099 12.0 0.0 14 5.0 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_13 PF13166.6 KXG47081.1 - 0.11 11.1 0.2 7.1 5.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KXG47081.1 - 0.12 11.5 0.3 7.2 5.7 0.0 2.5 3 0 0 3 3 2 0 NB-ARC domain AAA_24 PF13479.6 KXG47081.1 - 0.14 11.9 0.9 21 4.8 0.1 2.8 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 KXG47081.1 - 0.32 10.3 7.1 5.2 6.3 0.1 3.7 5 0 0 5 5 4 0 KaiC Glyco_hydro_64 PF16483.5 KXG47082.1 - 2e-137 458.4 6.6 2.4e-137 458.2 6.6 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase NCE101 PF11654.8 KXG47083.1 - 0.053 13.2 0.5 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Non-classical export protein 1 LLC1 PF14945.6 KXG47083.1 - 0.94 10.1 3.5 1 9.9 0.9 2.3 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Methyltransf_2 PF00891.18 KXG47084.1 - 1.1e-22 80.4 0.0 1.9e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Rrf2 PF02082.20 KXG47084.1 - 0.0027 18.0 0.1 0.025 14.9 0.0 2.5 3 0 0 3 3 3 1 Transcriptional regulator HTH_IclR PF09339.10 KXG47084.1 - 0.0095 15.7 1.0 0.019 14.7 0.3 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain DUF4082 PF13313.6 KXG47084.1 - 0.056 13.5 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) Methyltransf_23 PF13489.6 KXG47084.1 - 0.071 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MarR_2 PF12802.7 KXG47084.1 - 0.076 12.9 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 MarR family Dimerisation PF08100.11 KXG47084.1 - 0.082 12.9 0.4 0.3 11.1 0.4 2.1 1 0 0 1 1 1 0 Dimerisation domain Peptidase_M24 PF00557.24 KXG47084.1 - 0.088 12.5 0.0 11 5.6 0.0 2.6 2 1 1 3 3 3 0 Metallopeptidase family M24 Dimerisation2 PF16864.5 KXG47084.1 - 0.13 12.3 0.1 0.36 10.8 0.1 1.7 1 0 0 1 1 1 0 Dimerisation domain ICAP-1_inte_bdg PF10480.9 KXG47085.1 - 0.14 12.1 0.9 0.22 11.5 0.9 1.2 1 0 0 1 1 1 0 Beta-1 integrin binding protein But2 PF09792.9 KXG47086.1 - 1.2e-52 178.0 0.6 2.7e-52 176.9 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain PAP2 PF01569.21 KXG47087.1 - 1.7e-28 99.0 1.6 2e-28 98.9 0.4 1.7 2 0 0 2 2 2 1 PAP2 superfamily SLATT_1 PF18181.1 KXG47087.1 - 0.01 15.7 0.1 0.077 12.9 0.0 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 PAP2_3 PF14378.6 KXG47087.1 - 0.077 12.7 2.9 0.29 10.8 2.9 2.0 1 1 0 1 1 1 0 PAP2 superfamily LapA_dom PF06305.11 KXG47087.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF2568 PF10823.8 KXG47088.1 - 0.083 13.2 4.8 0.27 11.6 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2568) COX7a PF02238.15 KXG47088.1 - 0.17 12.3 1.0 12 6.3 0.0 2.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII UNC-50 PF05216.13 KXG47088.1 - 0.79 9.2 9.4 1.5 8.3 9.4 1.7 1 1 0 1 1 1 0 UNC-50 family UxuA PF03786.13 KXG47089.1 - 0.066 12.0 0.0 0.092 11.6 0.0 1.3 1 1 0 1 1 1 0 D-mannonate dehydratase (UxuA) TSP_3 PF02412.18 KXG47090.1 - 0.11 12.2 0.4 0.19 11.5 0.4 1.3 1 0 0 1 1 1 0 Thrombospondin type 3 repeat SARAF PF06682.12 KXG47091.1 - 2.1 7.9 4.4 0.88 9.2 0.7 1.8 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis ANAPC4_WD40 PF12894.7 KXG47092.1 - 5.6e-08 33.0 0.7 3.8 7.9 0.0 5.9 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PGAP1 PF07819.13 KXG47092.1 - 9.2e-05 22.3 0.1 0.00026 20.8 0.1 1.7 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KXG47092.1 - 0.006 17.2 0.1 0.041 14.5 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 KXG47092.1 - 0.007 15.9 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) WD40 PF00400.32 KXG47092.1 - 0.014 16.2 8.5 4.7 8.3 0.0 6.4 5 2 1 6 6 6 0 WD domain, G-beta repeat AAA_16 PF13191.6 KXG47092.1 - 0.054 13.9 0.0 0.25 11.7 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain Fructosamin_kin PF03881.14 KXG47093.1 - 3.8e-43 147.8 0.0 4.5e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KXG47093.1 - 8.5e-05 22.6 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.16 KXG47094.1 - 2.5e-27 95.7 3.3 3.1e-27 95.5 3.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG47094.1 - 1.9e-05 23.7 1.2 0.00015 20.8 0.1 2.0 1 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXG47094.1 - 3e-05 22.6 0.1 4.4e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KXG47094.1 - 0.25 9.7 1.9 0.26 9.6 0.2 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector Acetyltransf_3 PF13302.7 KXG47096.1 - 2e-34 119.2 0.0 2.6e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG47096.1 - 0.00025 21.2 0.0 0.003 17.8 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family DAO PF01266.24 KXG47097.1 - 7.5e-44 150.7 0.0 8.5e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXG47097.1 - 0.0027 17.0 0.1 0.0047 16.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG47097.1 - 0.0037 16.4 6.6 0.32 10.0 6.6 2.1 1 1 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 KXG47097.1 - 0.015 15.2 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KXG47097.1 - 0.035 13.4 2.8 0.039 13.3 0.7 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KXG47097.1 - 0.036 13.1 1.6 0.25 10.4 0.3 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KXG47097.1 - 0.082 13.1 0.3 0.19 12.0 0.3 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXG47097.1 - 0.088 11.5 2.3 2.8 6.6 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 KXG47097.1 - 0.1 11.8 1.0 0.65 9.2 1.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 KXG47097.1 - 0.13 12.4 0.2 0.32 11.2 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ribosomal_S2 PF00318.20 KXG47098.1 - 5.5e-66 221.9 0.1 7.9e-65 218.1 0.1 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 Rick_17kDa_Anti PF05433.15 KXG47099.1 - 7.1e-06 25.8 13.6 1.4e-05 24.9 13.6 1.5 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KXG47099.1 - 0.018 15.0 12.4 0.041 13.9 12.4 1.7 1 0 0 1 1 1 0 Glycine zipper PT-VENN PF04829.13 KXG47099.1 - 1 9.5 4.9 1.7 8.8 4.9 1.3 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Transgly_assoc PF04226.13 KXG47099.1 - 2 8.7 11.6 3.3 8.0 11.6 1.3 1 0 0 1 1 1 0 Transglycosylase associated protein SURF6 PF04935.12 KXG47100.1 - 4.5e-49 166.9 35.5 4.5e-49 166.9 35.5 3.9 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 KXG47100.1 - 2.7e-17 63.1 1.1 2.7e-17 63.1 1.1 7.8 8 1 0 8 8 8 1 60S ribosome biogenesis protein Rrp14 Fer4 PF00037.27 KXG47101.1 - 3.8e-14 51.8 15.9 3.5e-08 32.9 4.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KXG47101.1 - 4.7e-13 49.5 10.5 7.3e-13 48.9 10.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KXG47101.1 - 1.3e-10 42.0 8.3 1.5e-05 25.8 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KXG47101.1 - 2.2e-10 40.5 21.8 3.8e-07 30.1 12.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KXG47101.1 - 7.8e-10 38.8 21.1 5.1e-08 32.9 10.8 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KXG47101.1 - 1.4e-09 37.9 5.9 0.00011 22.2 0.4 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXG47101.1 - 8.4e-09 35.8 2.8 0.0002 21.8 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KXG47101.1 - 1.6e-06 28.0 17.5 0.00038 20.4 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KXG47101.1 - 4.8e-06 26.3 12.5 0.01 15.9 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KXG47101.1 - 1.5e-05 25.2 11.0 0.00028 21.1 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KXG47101.1 - 8.8e-05 23.0 11.9 0.016 15.7 1.9 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KXG47101.1 - 0.0095 16.1 5.4 0.69 10.2 0.2 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 KXG47101.1 - 0.037 14.2 8.9 1.1 9.4 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KXG47101.1 - 0.042 14.4 15.3 0.71 10.5 4.3 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KXG47101.1 - 0.064 14.2 15.7 0.11 13.4 3.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 KXG47101.1 - 0.093 12.9 5.9 0.38 10.9 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 KXG47101.1 - 0.25 12.2 11.5 1.9 9.4 1.7 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain DUF4451 PF14616.6 KXG47101.1 - 0.93 9.7 4.3 4.8 7.4 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) PP-binding PF00550.25 KXG47102.1 - 6.5e-11 42.4 0.1 9e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KXG47102.1 - 5.3e-06 26.6 0.1 6.9e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 Acyl-carrier GPP34 PF05719.11 KXG47103.1 - 1.1e-65 221.5 0.1 1.4e-65 221.1 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) ADH_zinc_N_2 PF13602.6 KXG47104.1 - 0.00017 22.7 0.1 0.0004 21.4 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG47104.1 - 0.011 15.6 0.0 0.043 13.7 0.0 1.9 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF2183 PF09949.9 KXG47105.1 - 6.1e-35 119.5 0.0 1.4e-34 118.3 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Chlamy_scaf PF09675.10 KXG47105.1 - 0.16 12.4 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) His_Phos_1 PF00300.22 KXG47106.1 - 3e-37 128.2 0.1 3.8e-37 127.9 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF16 PF01519.16 KXG47107.1 - 0.0048 17.4 12.1 0.011 16.2 3.2 2.8 2 0 0 2 2 2 2 Protein of unknown function DUF16 Ribo_biogen_C PF04034.13 KXG47108.1 - 2.9e-50 169.2 0.0 4.1e-50 168.8 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KXG47108.1 - 2.7e-11 43.1 1.0 2.7e-11 43.1 1.0 1.6 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI Nop53 PF07767.11 KXG47108.1 - 0.08 12.3 10.6 0.12 11.7 10.6 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) NOA36 PF06524.12 KXG47108.1 - 1.5 8.1 16.3 2.7 7.2 16.3 1.4 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KXG47108.1 - 8.2 4.4 21.6 11 4.0 21.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KXG47108.1 - 9.1 5.6 23.9 13 5.1 23.9 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KXG47108.1 - 9.1 4.4 23.9 12 4.0 23.9 1.1 1 0 0 1 1 1 0 Nop14-like family VHS PF00790.19 KXG47109.1 - 5.5e-45 152.7 0.0 2.2e-44 150.8 0.0 2.0 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 KXG47109.1 - 4.8e-24 84.8 0.3 1.5e-23 83.2 0.3 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 KXG47109.1 - 5.6e-21 74.6 1.0 1.2e-20 73.5 0.1 2.2 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 KXG47109.1 - 1e-07 31.5 0.5 6.1e-07 29.0 0.1 2.4 2 0 0 2 2 2 1 GGA N-GAT domain Mei5 PF10376.9 KXG47109.1 - 0.046 13.6 2.3 0.085 12.7 2.3 1.4 1 0 0 1 1 1 0 Double-strand recombination repair protein CTD PF12815.7 KXG47110.1 - 0.0015 19.1 4.2 0.0051 17.3 4.2 1.9 1 0 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Sugar_tr PF00083.24 KXG47111.1 - 9.3e-28 97.3 10.0 1.4e-27 96.7 10.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter CBS PF00571.28 KXG47111.1 - 2.8e-17 62.9 4.2 2.1e-05 24.8 0.0 5.5 5 0 0 5 5 5 4 CBS domain MFS_1 PF07690.16 KXG47111.1 - 8.1e-11 41.4 28.5 7.6e-09 34.9 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 KXG47112.1 - 3e-09 36.8 9.6 5e-09 36.1 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YvfG PF09628.10 KXG47112.1 - 0.15 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 YvfG protein HD PF01966.22 KXG47113.1 - 1.1e-06 28.9 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 HD domain HD_4 PF13328.6 KXG47113.1 - 0.021 14.6 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 HD domain PhyH PF05721.13 KXG47114.1 - 7e-30 104.9 0.1 9.3e-30 104.5 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KXG47114.1 - 0.00013 22.3 0.0 0.00031 21.1 0.0 1.7 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 KXG47114.1 - 0.01 16.7 0.1 0.02 15.8 0.1 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily MOSC PF03473.17 KXG47115.1 - 6.9e-32 110.2 0.0 1.3e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 KXG47115.1 - 5.8e-27 94.6 0.0 9.8e-27 93.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 KXG47115.1 - 9e-22 77.2 0.0 2.5e-21 75.8 0.0 1.8 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Mitoc_mL59 PF18126.1 KXG47116.1 - 2.8e-45 153.8 5.8 3.7e-45 153.4 5.8 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 TPR_14 PF13428.6 KXG47117.1 - 7e-07 29.5 10.9 0.0016 19.1 0.1 7.6 10 0 0 10 10 10 1 Tetratricopeptide repeat Suf PF05843.14 KXG47117.1 - 2.8e-06 27.6 2.7 0.003 17.6 0.1 3.2 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KXG47117.1 - 0.012 16.1 0.4 9.7 6.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat FAT PF02259.23 KXG47117.1 - 0.044 13.0 0.0 0.12 11.6 0.0 1.6 1 1 0 1 1 1 0 FAT domain HAT PF02184.16 KXG47117.1 - 7.1 6.7 25.8 11 6.0 0.4 6.8 7 0 0 7 7 7 0 HAT (Half-A-TPR) repeat DEAD PF00270.29 KXG47118.1 - 5.7e-47 159.7 0.0 5.8e-46 156.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG47118.1 - 9.5e-30 103.2 0.0 1.1e-28 99.8 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG47118.1 - 0.0021 18.1 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3334 PF11813.8 KXG47118.1 - 0.033 13.9 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) DUF2986 PF11661.8 KXG47118.1 - 0.06 13.9 5.8 0.36 11.4 5.8 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2986) PRAI PF00697.22 KXG47118.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase ERAP1_C PF11838.8 KXG47119.1 - 6e-92 308.5 0.0 5.3e-90 302.2 0.0 2.4 2 0 0 2 2 2 2 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KXG47119.1 - 1e-84 283.5 0.5 1.5e-84 282.9 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KXG47119.1 - 4.2e-56 190.1 1.0 6.7e-56 189.4 1.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 KXG47119.1 - 0.0013 18.8 0.1 0.0026 17.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) AA_permease_2 PF13520.6 KXG47120.1 - 2.4e-91 306.7 39.6 3e-91 306.4 39.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG47120.1 - 6.3e-19 67.9 34.9 9.9e-19 67.3 34.9 1.3 1 1 0 1 1 1 1 Amino acid permease DUF3543 PF12063.8 KXG47122.1 - 3.6e-89 298.5 0.0 6.1e-89 297.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KXG47122.1 - 4.4e-62 209.8 0.0 7.7e-62 209.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG47122.1 - 6.3e-43 146.9 0.0 1.1e-42 146.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXG47122.1 - 0.1 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Diphthami_syn_2 PF01902.17 KXG47123.1 - 3.2e-17 62.8 0.0 6.2e-12 45.5 0.0 3.1 2 1 0 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KXG47123.1 - 1.6e-14 53.9 0.1 3e-07 30.5 0.0 3.8 4 0 0 4 4 4 2 Endoribonuclease L-PSP zf-C2H2 PF00096.26 KXG47124.1 - 4e-12 45.9 13.5 1.9e-06 28.0 0.4 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXG47124.1 - 4.8e-08 33.2 10.0 0.0022 18.7 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXG47124.1 - 7.9e-08 32.4 9.9 6.7e-07 29.5 4.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXG47124.1 - 1.2e-05 25.4 3.2 0.0099 16.1 0.5 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXG47124.1 - 0.00015 21.7 9.2 0.0068 16.4 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KXG47124.1 - 0.0025 17.4 3.0 1.1 9.0 0.3 2.6 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 KXG47124.1 - 0.0028 18.0 12.2 0.0066 16.8 0.3 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-LYAR PF08790.11 KXG47124.1 - 0.13 12.2 1.7 15 5.6 0.1 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-BED PF02892.15 KXG47124.1 - 0.13 12.3 5.5 0.052 13.6 1.5 2.1 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_3rep PF18868.1 KXG47124.1 - 0.25 12.0 1.9 5.6 7.7 0.4 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 KXG47124.1 - 0.43 11.0 3.5 7.3 7.0 0.4 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KXG47124.1 - 0.44 11.0 6.7 58 4.2 6.7 2.7 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KXG47124.1 - 0.44 10.3 7.8 8.8 6.2 0.0 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type PITH PF06201.13 KXG47125.1 - 3.2e-35 121.6 0.0 5.2e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KXG47125.1 - 2.1e-28 98.3 0.1 4e-28 97.4 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXG47125.1 - 2.5e-06 27.9 0.4 5.6e-05 23.5 0.4 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXG47125.1 - 4.6e-06 26.9 0.0 0.0013 19.0 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 KXG47125.1 - 2.7e-05 23.7 0.0 7e-05 22.3 0.1 1.6 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KXG47125.1 - 0.0002 21.2 0.0 0.00032 20.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KXG47125.1 - 0.00044 20.2 0.1 0.02 14.8 0.0 2.3 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KXG47125.1 - 0.0033 17.2 0.2 0.75 9.5 0.0 2.3 1 1 1 2 2 2 2 Redoxin HyaE PF07449.11 KXG47125.1 - 0.097 12.6 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 KXG47125.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin zf-CSL PF05207.13 KXG47126.1 - 1.4e-18 66.4 0.7 2e-18 65.8 0.7 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KXG47126.1 - 8.3e-12 45.1 0.4 6.6e-07 29.4 0.1 2.3 2 0 0 2 2 2 2 DnaJ domain peroxidase PF00141.23 KXG47127.1 - 2.7e-49 167.9 0.0 4.4e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase ArfGap PF01412.18 KXG47128.1 - 2.4e-34 117.9 0.1 6.5e-34 116.5 0.1 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Glyco_transf_22 PF03901.17 KXG47129.1 - 1.8e-80 271.3 16.9 2.2e-80 271.0 16.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family EF-hand_11 PF08976.11 KXG47129.1 - 0.17 12.8 0.0 0.35 11.8 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain Delta_lysin PF05372.11 KXG47129.1 - 0.26 10.6 0.9 6.9 6.1 0.1 2.3 2 0 0 2 2 2 0 Delta lysin family Aminotran_3 PF00202.21 KXG47130.1 - 5.3e-117 390.9 0.0 6.1e-117 390.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXG47130.1 - 0.061 12.5 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KXG47130.1 - 0.2 10.9 0.0 0.4 9.9 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase ABC_membrane PF00664.23 KXG47131.1 - 3.5e-54 184.3 40.4 1.7e-34 119.8 21.1 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KXG47131.1 - 4.5e-46 156.8 0.0 8.6e-25 87.8 0.0 2.8 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 KXG47131.1 - 1.3e-06 28.5 0.1 0.016 15.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 KXG47131.1 - 1.7e-06 27.6 1.9 0.44 9.9 0.2 3.7 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KXG47131.1 - 6.4e-05 22.3 0.0 0.014 14.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 KXG47131.1 - 6.8e-05 22.8 0.3 0.079 12.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KXG47131.1 - 0.00019 21.4 1.4 0.17 11.7 0.1 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXG47131.1 - 0.00023 21.6 0.2 0.82 10.0 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KXG47131.1 - 0.00049 19.8 3.3 0.32 10.8 0.1 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 KXG47131.1 - 0.0034 17.5 2.1 0.33 11.0 0.1 2.7 2 0 0 2 2 2 1 Dynamin family MeaB PF03308.16 KXG47131.1 - 0.0072 15.3 0.7 2.4 7.1 0.2 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 KXG47131.1 - 0.01 15.6 0.3 4 7.0 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KXG47131.1 - 0.019 15.3 2.8 6.7 7.0 0.1 3.7 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.6 KXG47131.1 - 0.019 15.5 3.9 0.36 11.3 0.2 3.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KXG47131.1 - 0.041 14.4 0.0 19 5.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain DciA PF05258.12 KXG47131.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA AAA PF00004.29 KXG47131.1 - 0.12 12.9 0.0 2.7 8.4 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KXG47131.1 - 0.12 11.9 0.0 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KXG47131.1 - 0.23 11.5 5.3 0.25 11.4 0.2 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_30 PF13604.6 KXG47131.1 - 0.37 10.5 1.7 5.3 6.7 0.1 2.8 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 KXG47131.1 - 3.2 8.0 6.0 1.3 9.2 0.1 3.0 3 0 0 3 3 2 0 AAA domain FMN_red PF03358.15 KXG47132.1 - 2.9e-29 101.8 0.0 4e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KXG47132.1 - 1.8e-08 34.3 0.0 2.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold DUF3328 PF11807.8 KXG47133.1 - 0.00066 19.5 2.1 0.016 15.0 1.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3328) Sugar_tr PF00083.24 KXG47137.1 - 2.9e-30 105.5 28.0 1.7e-22 79.9 8.0 2.8 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 KXG47137.1 - 3.1e-28 98.7 28.7 4.8e-28 98.1 27.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.6 KXG47137.1 - 0.96 10.0 7.7 11 6.5 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) Transferase PF02458.15 KXG47138.1 - 1.1e-35 123.1 0.0 1.3e-25 90.0 0.0 2.9 2 1 0 2 2 2 2 Transferase family Pyr_redox_3 PF13738.6 KXG47139.1 - 4.4e-19 68.9 0.0 2.3e-17 63.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG47139.1 - 4.3e-15 55.7 0.0 1.8e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXG47139.1 - 1.6e-14 53.2 0.1 2.7e-12 45.9 0.1 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXG47139.1 - 5.8e-10 38.8 0.1 1e-07 31.4 0.1 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXG47139.1 - 3.5e-06 27.2 0.0 1.5e-05 25.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXG47139.1 - 2.1e-05 25.0 0.5 0.47 11.0 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXG47139.1 - 0.00062 19.1 0.1 0.0034 16.7 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 KXG47139.1 - 0.0023 17.1 0.0 0.0069 15.5 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 KXG47139.1 - 0.0026 17.1 0.1 0.024 14.0 0.1 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 KXG47139.1 - 0.008 15.4 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 1 Thi4 family SnoaL_2 PF12680.7 KXG47139.1 - 0.014 16.0 0.1 0.094 13.4 0.0 2.3 3 0 0 3 3 3 0 SnoaL-like domain HI0933_like PF03486.14 KXG47139.1 - 0.015 14.0 0.0 0.057 12.1 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.20 KXG47139.1 - 0.029 14.4 0.0 3.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KXG47139.1 - 0.044 13.8 0.3 3.5 7.6 0.1 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 KXG47139.1 - 0.051 13.1 0.0 3.3 7.2 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KXG47139.1 - 0.067 13.6 0.0 9.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 KXG47139.1 - 0.11 11.8 0.0 0.48 9.7 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KXG47139.1 - 0.12 12.2 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KXG47139.1 - 0.21 10.7 0.0 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A UreE_N PF02814.15 KXG47140.1 - 0.15 11.7 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain SLAC1 PF03595.17 KXG47141.1 - 2.3e-53 181.6 39.2 5.9e-53 180.2 39.2 1.6 1 1 0 1 1 1 1 Voltage-dependent anion channel Abhydrolase_9_N PF15420.6 KXG47141.1 - 4 7.4 14.3 2.1 8.3 3.1 2.8 2 1 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus CDC45 PF02724.14 KXG47143.1 - 0.084 11.2 0.1 0.12 10.7 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein ANAPC4_WD40 PF12894.7 KXG47144.1 - 0.0001 22.5 0.0 3.8 7.9 0.0 3.7 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KXG47144.1 - 0.027 14.4 0.0 0.23 11.3 0.0 2.5 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term EspF PF04806.12 KXG47144.1 - 4.6 7.7 15.1 0.043 14.2 5.0 2.6 2 0 0 2 2 2 0 EspF protein repeat Fungal_trans PF04082.18 KXG47145.1 - 3.9e-14 52.3 0.0 8.7e-14 51.2 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG47145.1 - 1.4e-06 28.3 7.0 3.4e-06 27.1 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NIF PF03031.18 KXG47146.1 - 7.6e-42 142.7 0.1 1e-41 142.3 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase F-box PF00646.33 KXG47147.1 - 0.051 13.5 0.1 2.7 8.0 0.1 2.5 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KXG47147.1 - 0.077 12.9 0.0 0.39 10.6 0.0 2.3 2 1 0 2 2 2 0 F-box-like JAB PF01398.21 KXG47148.1 - 2.6e-33 114.5 0.0 5.4e-33 113.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KXG47148.1 - 2.2e-11 44.2 1.0 3.4e-11 43.5 1.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KXG47148.1 - 7e-08 32.3 0.0 3.2e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Hist_deacetyl PF00850.19 KXG47149.1 - 1.4e-82 277.7 1.2 1.5e-82 277.5 0.0 1.7 3 0 0 3 3 3 1 Histone deacetylase domain Ribosomal_L14 PF00238.19 KXG47150.1 - 3.6e-34 117.5 0.0 4.3e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Endonuc-FokI_C PF09254.11 KXG47150.1 - 0.078 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal PH PF00169.29 KXG47152.1 - 9.5e-12 45.4 0.0 5.6e-11 42.9 0.0 2.2 1 1 0 1 1 1 1 PH domain SAM_2 PF07647.17 KXG47152.1 - 4.6e-10 39.5 0.1 7.8e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 KXG47152.1 - 1.4e-06 28.1 0.0 2.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXG47152.1 - 2.4e-06 27.0 0.0 4.9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SAM_1 PF00536.30 KXG47152.1 - 0.00013 22.3 0.1 0.00025 21.4 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 KXG47152.1 - 0.0095 16.4 0.6 0.028 14.8 0.1 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KXG47152.1 - 0.094 13.0 0.0 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain zf-MIZ PF02891.20 KXG47153.1 - 5.4e-10 38.9 1.3 1.4e-09 37.6 1.3 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KXG47153.1 - 0.0031 17.3 0.7 0.009 15.8 0.7 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF5102 PF17104.5 KXG47154.1 - 1e-109 367.1 3.9 2e-109 366.1 3.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Nsp1_C PF05064.13 KXG47155.1 - 9.9e-41 138.2 0.5 2.8e-40 136.8 0.5 1.7 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KXG47155.1 - 8.2e-08 33.0 149.9 0.0027 18.5 43.0 7.3 1 1 5 6 6 5 3 Nucleoporin FG repeat region ParB PF08775.10 KXG47155.1 - 0.032 14.7 0.5 0.067 13.7 0.5 1.5 1 0 0 1 1 1 0 ParB family Laminin_II PF06009.12 KXG47155.1 - 0.089 12.8 8.0 16 5.5 2.0 3.1 1 1 2 3 3 3 0 Laminin Domain II SGT1 PF07093.11 KXG47155.1 - 0.15 10.5 1.4 0.2 10.1 1.4 1.1 1 0 0 1 1 1 0 SGT1 protein DUF1664 PF07889.12 KXG47155.1 - 0.21 11.6 4.3 1.2 9.2 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 KXG47155.1 - 0.3 11.6 3.4 0.41 11.2 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF4200 PF13863.6 KXG47155.1 - 0.52 10.7 5.0 2.5 8.5 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AAA_13 PF13166.6 KXG47155.1 - 0.6 8.7 2.0 0.88 8.1 2.0 1.2 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 KXG47155.1 - 0.66 9.3 5.0 1.2 8.4 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 KXG47155.1 - 0.91 10.2 7.6 12 6.6 5.0 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF948 PF06103.11 KXG47155.1 - 0.97 9.7 5.4 1.3 9.3 1.5 2.8 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) OmpH PF03938.14 KXG47155.1 - 1.1 9.6 6.5 0.65 10.3 0.3 2.3 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Snapin_Pallidin PF14712.6 KXG47155.1 - 2.7 8.5 3.9 6.2 7.3 0.1 2.3 2 0 0 2 2 2 0 Snapin/Pallidin V-SNARE PF05008.15 KXG47155.1 - 3.7 8.0 6.3 9.2 6.7 0.2 3.0 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus APG6_N PF17675.1 KXG47155.1 - 4 8.0 6.5 11 6.6 5.7 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Ank_2 PF12796.7 KXG47156.1 - 8.4e-56 186.5 5.1 5.2e-12 46.2 0.1 6.0 3 3 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG47156.1 - 5.3e-54 179.9 0.8 1.2e-10 41.7 0.0 10.0 1 1 10 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 KXG47156.1 - 1.3e-47 158.2 5.6 8e-05 22.9 0.0 11.5 12 0 0 12 12 12 8 Ankyrin repeat Ank_3 PF13606.6 KXG47156.1 - 1.8e-45 147.6 3.3 0.00062 20.0 0.0 11.6 11 1 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 KXG47156.1 - 8.7e-43 143.8 2.9 1.9e-08 34.4 0.0 8.6 5 2 3 8 8 8 7 Ankyrin repeats (many copies) IATP PF04568.12 KXG47156.1 - 2.8e-33 114.3 0.2 6e-33 113.2 0.2 1.6 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF2730 PF10805.8 KXG47156.1 - 0.021 14.9 0.2 0.052 13.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) F-box-like PF12937.7 KXG47156.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 F-box-like bZIP_1 PF00170.21 KXG47156.1 - 2.3 8.4 12.4 3.7 7.7 0.4 2.6 2 0 0 2 2 2 0 bZIP transcription factor 14-3-3 PF00244.20 KXG47157.1 - 3.7e-105 350.3 4.9 4.3e-105 350.1 4.9 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 KXG47157.1 - 0.1 11.0 3.0 0.14 10.5 3.0 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF2205 PF10224.9 KXG47158.1 - 5.1e-33 112.9 1.8 5.1e-33 112.9 1.8 1.5 2 0 0 2 2 2 1 Short coiled-coil protein TPR_MLP1_2 PF07926.12 KXG47158.1 - 0.0049 16.9 2.1 0.0077 16.3 2.1 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein HALZ PF02183.18 KXG47158.1 - 0.0092 16.2 4.0 0.048 13.9 0.1 2.3 1 1 1 2 2 2 1 Homeobox associated leucine zipper YabA PF06156.13 KXG47158.1 - 0.013 16.1 1.9 0.019 15.6 1.9 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DUF2884 PF11101.8 KXG47158.1 - 0.018 14.6 1.2 0.025 14.1 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DivIC PF04977.15 KXG47158.1 - 0.039 13.7 1.5 0.063 13.0 1.5 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.21 KXG47158.1 - 0.073 13.2 4.1 0.18 11.9 4.1 1.7 1 1 0 1 1 1 0 bZIP transcription factor Swi5 PF07061.11 KXG47158.1 - 0.087 12.9 1.1 0.15 12.2 1.1 1.3 1 0 0 1 1 1 0 Swi5 Sas10_Utp3 PF04000.15 KXG47158.1 - 0.092 13.4 0.2 0.19 12.4 0.2 1.5 1 0 0 1 1 1 0 Sas10/Utp3/C1D family Glutaredoxin2_C PF04399.13 KXG47158.1 - 0.098 12.5 0.1 0.13 12.1 0.1 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Tup_N PF08581.10 KXG47158.1 - 0.11 12.9 2.3 9 6.7 0.3 2.2 1 1 1 2 2 2 0 Tup N-terminal XhlA PF10779.9 KXG47158.1 - 0.14 12.3 0.5 0.3 11.3 0.4 1.6 1 1 0 1 1 1 0 Haemolysin XhlA DUF5320 PF17253.2 KXG47158.1 - 0.2 12.7 2.3 0.33 12.1 1.3 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Glyco_hydro_76 PF03663.14 KXG47159.1 - 2.7e-19 69.9 0.1 2.3e-12 47.1 0.0 2.6 3 1 0 3 3 3 2 Glycosyl hydrolase family 76 RRM_1 PF00076.22 KXG47160.1 - 1.6e-15 56.7 0.0 2.3e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXG47160.1 - 0.00068 19.2 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXG47160.1 - 0.032 14.3 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif RRM_occluded PF16842.5 KXG47160.1 - 0.052 13.4 0.0 0.1 12.4 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif HMA PF00403.26 KXG47160.1 - 0.1 13.0 0.0 0.18 12.3 0.0 1.4 1 1 0 1 1 1 0 Heavy-metal-associated domain XFP_N PF09364.10 KXG47160.1 - 0.14 10.9 0.0 0.48 9.2 0.0 1.7 1 1 1 2 2 2 0 XFP N-terminal domain Bax1-I PF01027.20 KXG47161.1 - 2.5e-33 115.6 11.1 4e-33 115.0 11.1 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF3995 PF13160.6 KXG47161.1 - 2 8.8 11.2 0.13 12.6 2.3 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3995) CGI-121 PF08617.10 KXG47162.1 - 5.3e-57 192.5 0.9 5.9e-57 192.3 0.9 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Slx4 PF09494.10 KXG47163.1 - 7.3e-27 93.1 0.0 1.3e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease Zn_clus PF00172.18 KXG47164.1 - 0.0002 21.4 9.3 0.00032 20.7 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TSC22 PF01166.18 KXG47164.1 - 0.0004 20.6 0.5 0.00088 19.5 0.4 1.6 2 0 0 2 2 2 1 TSC-22/dip/bun family DUF4201 PF13870.6 KXG47164.1 - 0.0007 19.4 0.6 0.0011 18.7 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) ZapB PF06005.12 KXG47164.1 - 0.00088 19.7 0.4 0.0017 18.8 0.4 1.5 2 0 0 2 2 2 1 Cell division protein ZapB AKNA PF12443.8 KXG47164.1 - 0.021 15.5 0.5 0.037 14.7 0.5 1.4 1 0 0 1 1 1 0 AT-hook-containing transcription factor DivIC PF04977.15 KXG47164.1 - 0.022 14.5 1.9 0.034 13.9 1.9 1.2 1 0 0 1 1 1 0 Septum formation initiator PspA_IM30 PF04012.12 KXG47164.1 - 0.04 13.5 0.5 0.059 12.9 0.5 1.2 1 0 0 1 1 1 0 PspA/IM30 family DUF3847 PF12958.7 KXG47164.1 - 0.05 13.7 1.2 0.097 12.8 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) CdvA PF18822.1 KXG47164.1 - 0.066 13.0 1.6 0.1 12.5 1.6 1.2 1 0 0 1 1 1 0 CdvA-like coiled-coil domain FliD_C PF07195.12 KXG47164.1 - 0.075 12.4 0.1 0.091 12.2 0.1 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Prefoldin PF02996.17 KXG47164.1 - 0.087 12.7 1.8 0.14 12.1 1.8 1.2 1 0 0 1 1 1 0 Prefoldin subunit bZIP_2 PF07716.15 KXG47164.1 - 0.21 11.7 4.0 0.4 10.8 4.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper MerR-DNA-bind PF09278.11 KXG47164.1 - 0.5 11.0 3.3 0.61 10.7 1.2 2.0 2 0 0 2 2 2 0 MerR, DNA binding DUF4618 PF15397.6 KXG47164.1 - 1.9 7.8 9.3 0.12 11.7 2.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) ER_lumen_recept PF00810.18 KXG47166.1 - 3e-43 148.2 9.4 4.8e-43 147.5 9.4 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KXG47166.1 - 0.011 15.5 0.2 0.011 15.5 0.2 4.2 5 2 0 5 5 5 0 PQ loop repeat Tlr3_TMD PF17968.1 KXG47166.1 - 0.06 13.5 2.8 0.2 11.9 2.8 1.9 1 0 0 1 1 1 0 Toll-like receptor 3 trans-membrane domain Myb_DNA-binding PF00249.31 KXG47167.1 - 8.8e-16 57.8 4.6 3.6e-09 36.7 0.7 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXG47167.1 - 4.7e-10 39.6 1.5 6.4e-06 26.3 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KXG47167.1 - 0.039 13.9 1.4 0.061 13.2 1.3 1.4 1 1 0 1 1 1 0 Myb DNA-binding like Transp_cyt_pur PF02133.15 KXG47168.1 - 3.6e-18 65.6 37.9 6.4e-18 64.7 37.9 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COX5B PF01215.19 KXG47169.1 - 1.7e-54 182.9 0.0 2.7e-54 182.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Myb_DNA-bind_6 PF13921.6 KXG47169.1 - 9.7e-06 25.8 4.2 9.9e-05 22.5 4.2 2.5 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXG47169.1 - 0.00056 20.0 0.2 0.00056 20.0 0.2 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain GHL15 PF14885.6 KXG47169.1 - 0.046 13.7 0.2 0.079 12.9 0.2 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 PROCN PF08083.11 KXG47170.1 - 4.2e-233 773.4 8.8 4.2e-233 773.4 8.8 1.9 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KXG47170.1 - 1.9e-126 420.4 1.4 3.6e-126 419.4 1.4 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KXG47170.1 - 2.8e-85 284.1 1.5 1.5e-57 194.0 0.1 3.2 3 0 0 3 3 3 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KXG47170.1 - 5.6e-81 269.9 2.5 1.6e-80 268.4 2.5 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KXG47170.1 - 4.6e-71 237.1 0.1 1e-70 236.0 0.1 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 KXG47170.1 - 9.2e-48 161.2 0.0 2.5e-47 159.8 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 KXG47170.1 - 3.4e-47 158.7 0.3 9.6e-47 157.3 0.3 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end_hint PF05203.16 KXG47170.1 - 1.6e-09 38.1 0.9 3.7e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 Hom_end-associated Hint Ribosomal_L34e PF01199.18 KXG47171.1 - 4e-39 132.8 0.4 4e-39 132.8 0.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 KXG47171.1 - 0.037 13.4 0.0 0.075 12.4 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Forkhead PF00250.18 KXG47172.1 - 1.3e-20 73.4 0.0 2.7e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain NRDE-2 PF08424.10 KXG47172.1 - 0.18 10.9 0.1 0.25 10.4 0.1 1.1 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Cactin_mid PF10312.9 KXG47173.1 - 5.7e-63 212.2 5.6 1e-62 211.4 5.6 1.4 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KXG47173.1 - 7.2e-58 194.0 4.2 1.2e-57 193.2 4.2 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF1087 PF06465.13 KXG47173.1 - 0.024 14.6 0.3 0.083 12.9 0.3 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) GARP PF16731.5 KXG47173.1 - 0.14 11.8 1.0 0.28 10.8 0.2 1.8 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma XLF PF09302.11 KXG47174.1 - 6.8e-54 182.7 0.8 1.1e-53 182.1 0.8 1.3 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component WD40 PF00400.32 KXG47175.1 - 5.3e-14 52.4 27.4 3.2e-05 24.6 0.3 7.3 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG47175.1 - 1.1e-07 32.1 0.1 1.3 9.4 0.0 5.3 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXG47175.1 - 2.8e-05 24.1 0.0 0.35 10.7 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A zf-C2H2_aberr PF17017.5 KXG47175.1 - 0.011 15.9 0.1 0.09 12.9 0.0 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger CLAMP PF14769.6 KXG47175.1 - 0.23 11.9 0.6 0.47 10.9 0.6 1.4 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Zn_ribbon_17 PF17120.5 KXG47175.1 - 1.3 8.7 11.2 4.1 7.1 11.2 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type ABC_membrane PF00664.23 KXG47176.1 - 3.9e-34 118.6 11.8 2.7e-33 115.8 8.2 2.6 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXG47176.1 - 2.2e-32 112.4 0.0 7e-32 110.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KXG47176.1 - 1.5e-07 31.1 0.0 2.6e-06 27.0 0.0 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXG47176.1 - 0.013 15.8 0.1 0.042 14.2 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 KXG47176.1 - 0.019 15.2 0.4 0.52 10.6 0.4 2.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KXG47176.1 - 0.033 14.5 0.6 0.25 11.6 0.6 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXG47176.1 - 0.037 13.8 0.2 0.095 12.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KXG47176.1 - 0.085 12.8 0.0 0.66 10.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KXG47176.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Alk_phosphatase PF00245.20 KXG47177.1 - 7.3e-104 348.0 0.0 9.6e-104 347.6 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase DUF498 PF04430.14 KXG47177.1 - 8.4e-28 96.6 0.0 1.8e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Metalloenzyme PF01676.18 KXG47177.1 - 0.00099 18.5 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily SET PF00856.28 KXG47178.1 - 4e-15 56.6 0.2 1.9e-14 54.4 0.2 2.2 1 1 0 1 1 1 1 SET domain TPR_14 PF13428.6 KXG47178.1 - 3.1e-11 43.1 1.8 0.14 13.0 0.0 5.6 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXG47178.1 - 7.7e-11 41.2 5.8 0.077 13.1 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXG47178.1 - 2.2e-08 33.6 4.7 0.00034 20.3 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXG47178.1 - 3.7e-05 24.3 1.2 1.6 9.5 0.1 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXG47178.1 - 0.0019 17.9 0.3 0.0083 15.8 0.3 2.2 1 1 0 1 1 1 1 TPR repeat TPR_6 PF13174.6 KXG47178.1 - 0.0019 18.7 1.8 8 7.3 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXG47178.1 - 0.0024 17.9 0.1 2.5 8.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat YfiO PF13525.6 KXG47178.1 - 0.011 15.5 0.1 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 Outer membrane lipoprotein TPR_12 PF13424.6 KXG47178.1 - 0.038 14.3 0.9 5.2 7.4 0.0 3.6 2 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG47178.1 - 0.043 14.0 1.4 1.6 9.0 0.5 3.6 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 AAA_22 PF13401.6 KXG47178.1 - 0.12 12.7 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain TPR_9 PF13371.6 KXG47178.1 - 0.88 9.8 6.3 1.4 9.2 0.6 3.6 3 2 1 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_16 PF00722.21 KXG47179.1 - 2.7e-45 154.0 7.8 4.9e-45 153.2 7.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MAGP PF05507.11 KXG47179.1 - 0.018 15.4 0.8 0.091 13.2 0.3 2.2 2 0 0 2 2 2 0 Microfibril-associated glycoprotein (MAGP) Chitin_bind_1 PF00187.19 KXG47179.1 - 1 9.9 15.3 2.3 8.7 15.3 1.5 1 0 0 1 1 1 0 Chitin recognition protein Voltage_CLC PF00654.20 KXG47181.1 - 2.1e-87 293.6 32.0 2.1e-87 293.6 32.0 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KXG47181.1 - 8.6e-12 45.3 0.0 0.00017 21.9 0.0 2.5 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.23 KXG47182.1 - 3.4e-15 56.1 2.1 3.4e-15 56.1 0.6 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXG47182.1 - 0.00058 20.2 1.2 0.00091 19.6 0.2 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 UCR_TM PF02921.14 KXG47183.1 - 3e-11 43.6 0.7 8.4e-11 42.2 0.7 1.8 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 KXG47183.1 - 5.9e-11 42.2 0.0 1.2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain She9_MDM33 PF05546.11 KXG47184.1 - 6.8e-88 293.7 10.5 1.1e-87 292.9 10.5 1.4 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.20 KXG47184.1 - 0.043 13.6 1.1 0.089 12.5 1.1 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein SARAF PF06682.12 KXG47184.1 - 0.6 9.7 5.9 0.49 10.0 4.7 1.5 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Pmp3 PF01679.17 KXG47185.1 - 4.5e-18 65.2 10.9 5.8e-18 64.8 10.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SH3_9 PF14604.6 KXG47186.1 - 1.5e-05 24.7 0.1 3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4690 PF15756.5 KXG47186.1 - 0.0023 18.5 1.2 0.005 17.4 0.2 2.0 2 0 0 2 2 2 1 Small Novel Rich in Cartilage SH3_1 PF00018.28 KXG47186.1 - 0.0098 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.10 KXG47186.1 - 0.025 14.0 0.5 0.053 12.9 0.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 KXG47186.1 - 0.21 11.6 0.1 0.41 10.6 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain CYYR1 PF10873.8 KXG47186.1 - 0.22 12.0 6.1 0.84 10.1 6.0 2.1 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 GST_N_3 PF13417.6 KXG47187.1 - 7e-16 58.4 0.0 1.3e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXG47187.1 - 4.9e-15 55.6 0.0 9.1e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXG47187.1 - 8.3e-15 54.8 0.0 1.5e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KXG47187.1 - 2.2e-05 24.6 0.0 4.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_5 PF16865.5 KXG47187.1 - 7e-05 23.4 0.0 0.00012 22.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cofilin_ADF PF00241.20 KXG47188.1 - 1.9e-35 121.3 0.4 2.1e-35 121.1 0.4 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein COX4 PF02936.14 KXG47189.1 - 1.2e-41 142.0 2.4 1.1e-25 90.3 0.1 2.1 2 0 0 2 2 2 2 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 KXG47189.1 - 0.027 14.9 1.6 0.054 14.0 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) DUF3143 PF11341.8 KXG47189.1 - 0.05 14.0 0.3 0.091 13.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) DUF1104 PF06518.11 KXG47189.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) ATP-synt_ab PF00006.25 KXG47190.1 - 3e-62 210.0 0.0 6e-62 209.1 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KXG47190.1 - 1.1e-22 80.3 2.7 5e-22 78.2 1.7 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 KXG47190.1 - 0.0027 17.1 0.2 0.0046 16.3 0.2 1.4 1 0 0 1 1 1 1 KaiC AAA PF00004.29 KXG47190.1 - 0.017 15.6 0.1 1.1 9.7 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KXG47190.1 - 0.018 14.2 0.3 0.098 11.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 KXG47190.1 - 0.037 14.4 0.8 0.43 10.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KXG47190.1 - 0.042 13.8 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 KXG47190.1 - 0.047 13.6 0.4 0.1 12.5 0.1 1.6 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 KXG47190.1 - 0.052 13.5 0.2 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain T3SS_ATPase_C PF18269.1 KXG47190.1 - 0.073 12.9 1.0 0.29 11.0 1.0 1.9 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain RNA_helicase PF00910.22 KXG47190.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF4618 PF15397.6 KXG47190.1 - 0.16 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Alpha-amylase_C PF02806.18 KXG47191.1 - 1.3e-24 86.5 0.0 3.3e-24 85.2 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KXG47191.1 - 6e-19 68.2 0.1 1.7e-18 66.8 0.1 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KXG47191.1 - 6.9e-15 55.4 0.2 1.9e-11 44.2 0.1 2.4 2 1 1 3 3 3 2 Alpha amylase, catalytic domain adh_short PF00106.25 KXG47194.1 - 1.1e-45 155.5 0.0 2.1e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG47194.1 - 1.1e-43 149.5 0.0 2e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ank_2 PF12796.7 KXG47194.1 - 1.2e-37 128.3 0.3 3.5e-14 53.1 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG47194.1 - 5.6e-28 97.0 0.0 2.6e-09 37.4 0.0 5.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG47194.1 - 5.2e-27 90.9 0.0 0.00062 20.0 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 KXG47194.1 - 3.5e-23 81.0 0.7 0.00016 21.9 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KXG47194.1 - 1.6e-21 76.1 0.2 2.9e-06 27.5 0.0 5.7 1 1 5 6 6 6 5 Ankyrin repeats (many copies) KR PF08659.10 KXG47194.1 - 2e-12 47.4 0.0 3.7e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Cnd1_N PF12922.7 KXG47194.1 - 0.092 12.6 0.5 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term zf-LITAF-like PF10601.9 KXG47195.1 - 6.3e-20 71.2 11.1 8.5e-20 70.8 11.1 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain RGS PF00615.19 KXG47198.1 - 0.0001 22.5 0.0 0.00039 20.7 0.0 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain Vg_Tdu PF07545.14 KXG47198.1 - 0.18 11.6 0.5 0.38 10.6 0.5 1.5 1 0 0 1 1 1 0 Vestigial/Tondu family NAD_binding_11 PF14833.6 KXG47199.1 - 6.8e-39 132.9 5.4 2.1e-29 102.2 0.0 2.3 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KXG47199.1 - 4e-37 127.8 1.6 7.2e-37 127.0 0.1 2.1 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KXG47199.1 - 0.00077 19.4 0.0 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXG47199.1 - 0.0011 19.6 1.8 0.0031 18.0 0.0 2.7 4 0 0 4 4 4 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh PF00984.19 KXG47199.1 - 0.061 13.5 0.0 2.9 8.1 0.0 2.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain 2-Hacid_dh_C PF02826.19 KXG47199.1 - 0.082 12.3 0.0 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pes-10 PF07149.11 KXG47199.1 - 0.18 10.8 0.1 0.25 10.3 0.1 1.1 1 0 0 1 1 1 0 Pes-10 F_bP_aldolase PF01116.20 KXG47200.1 - 1.5e-84 283.8 0.1 1.7e-84 283.6 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II p450 PF00067.22 KXG47203.1 - 4.2e-57 193.9 0.0 5.4e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fer2_3 PF13085.6 KXG47204.1 - 7e-32 109.7 0.0 1.1e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KXG47204.1 - 5.9e-09 36.4 5.2 5.9e-09 36.4 5.2 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KXG47204.1 - 2.2e-07 30.9 3.0 2.2e-07 30.9 3.0 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXG47204.1 - 1.2e-06 28.8 8.4 1.2e-06 28.8 8.4 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KXG47204.1 - 0.0061 17.1 5.2 0.0061 17.1 5.2 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KXG47204.1 - 0.016 15.2 0.6 0.016 15.2 0.6 2.2 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 KXG47204.1 - 1.8 8.8 13.0 4.7 7.5 9.9 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 KXG47204.1 - 5.6 7.2 7.9 1.4 9.1 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain NmrA PF05368.13 KXG47205.1 - 2.3e-13 50.3 0.0 3.5e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG47205.1 - 1.4e-08 34.8 0.0 2.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KXG47205.1 - 0.00054 19.9 0.0 0.009 15.9 0.0 2.1 2 0 0 2 2 2 1 KR domain Amidase PF01425.21 KXG47207.1 - 6.5e-70 236.3 0.3 2e-66 224.8 0.0 2.1 2 0 0 2 2 2 2 Amidase Pec_lyase_C PF00544.19 KXG47208.1 - 9.7e-17 61.3 12.4 1.2e-15 57.7 12.4 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXG47208.1 - 7.9e-06 25.8 12.7 1.7e-05 24.7 12.7 1.6 1 0 0 1 1 1 1 Right handed beta helix region Ferritin_2 PF13668.6 KXG47209.1 - 1.1e-06 28.9 0.0 1.7e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Sugar_tr PF00083.24 KXG47210.1 - 3.7e-82 276.6 16.7 4.3e-82 276.4 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG47210.1 - 3.2e-29 101.9 19.2 3.2e-29 101.9 19.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXG47210.1 - 1.2e-05 24.1 0.3 1.2e-05 24.1 0.3 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 KXG47210.1 - 0.0014 17.2 3.1 0.002 16.6 1.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PhyH PF05721.13 KXG47211.1 - 0.0019 18.5 0.1 0.0037 17.5 0.1 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_36 PF17167.4 KXG47211.1 - 0.17 10.6 0.0 0.37 9.4 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase 36 superfamily, catalytic domain MFS_1 PF07690.16 KXG47212.1 - 2.9e-20 72.5 58.1 2.9e-20 72.5 58.1 3.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG47212.1 - 1.6e-06 27.3 16.2 1.6e-06 27.3 16.2 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter ArAE_2_N PF10337.9 KXG47213.1 - 3.2e-61 207.8 25.5 1.1e-50 173.1 1.7 4.2 3 1 1 4 4 4 2 Putative ER transporter, 6TM, N-terminal adh_short PF00106.25 KXG47213.1 - 2.5e-28 98.8 1.9 8.5e-17 61.3 0.5 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXG47213.1 - 2.5e-26 92.7 2.0 1.2e-14 54.5 0.3 2.7 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase FUSC_2 PF13515.6 KXG47213.1 - 7.5e-16 58.4 16.9 7.5e-16 58.4 16.9 3.0 3 1 0 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KXG47213.1 - 8.7e-14 51.9 0.0 4e-13 49.7 0.0 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 KR PF08659.10 KXG47213.1 - 0.0001 22.3 0.7 0.00083 19.3 0.1 2.3 2 0 0 2 2 2 1 KR domain DPBB_1 PF03330.18 KXG47214.1 - 2.5e-05 24.5 0.0 5.4e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Lytic transglycolase Ntox17 PF15524.6 KXG47214.1 - 0.031 14.6 0.1 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 Novel toxin 17 ThiF PF00899.21 KXG47215.1 - 1.1e-59 201.7 0.0 1.6e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KXG47215.1 - 1.1e-07 32.3 0.1 5.5e-07 30.1 0.0 2.2 3 0 0 3 3 3 1 Rhodanese-like domain Shikimate_DH PF01488.20 KXG47215.1 - 0.014 15.4 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KXG47215.1 - 0.02 15.3 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ADIP PF11559.8 KXG47215.1 - 0.031 14.4 0.1 0.054 13.6 0.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KXG47215.1 - 0.15 12.1 0.2 0.34 10.9 0.2 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 KXG47215.1 - 0.16 11.3 0.3 0.23 10.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sugar_tr PF00083.24 KXG47216.1 - 2.1e-129 432.3 21.7 2.5e-129 432.1 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG47216.1 - 5.2e-25 88.1 35.3 2.9e-24 85.6 30.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4381 PF14316.6 KXG47216.1 - 0.084 13.1 0.1 0.56 10.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Podoplanin PF05808.11 KXG47218.1 - 6.6e-07 29.6 2.4 6.6e-07 29.6 2.4 1.9 3 0 0 3 3 3 1 Podoplanin TMEM154 PF15102.6 KXG47218.1 - 1.2e-05 25.3 0.3 2.4e-05 24.3 0.3 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF4690 PF15756.5 KXG47218.1 - 1.2e-05 25.8 4.0 3.4e-05 24.4 4.0 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage DUF4064 PF13273.6 KXG47218.1 - 0.00039 20.6 1.2 0.00073 19.8 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) SKG6 PF08693.10 KXG47218.1 - 0.00049 19.5 1.1 0.0011 18.3 1.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 KXG47218.1 - 0.0014 19.1 4.3 0.0014 19.1 4.3 1.8 2 0 0 2 2 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glycophorin_A PF01102.18 KXG47218.1 - 0.002 18.4 3.7 0.003 17.8 3.0 1.7 1 1 0 1 1 1 1 Glycophorin A CYYR1 PF10873.8 KXG47218.1 - 0.0082 16.6 3.2 0.016 15.6 3.0 1.5 1 1 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 DUF1772 PF08592.11 KXG47218.1 - 0.0082 16.5 2.3 0.018 15.3 2.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) CD34_antigen PF06365.12 KXG47218.1 - 0.013 15.1 0.0 0.04 13.5 0.0 1.8 1 1 0 1 1 1 0 CD34/Podocalyxin family AJAP1_PANP_C PF15298.6 KXG47218.1 - 0.02 15.1 3.6 0.038 14.2 3.6 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF4330 PF14221.6 KXG47218.1 - 0.022 15.0 0.5 0.046 13.9 0.0 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4330) BatD PF13584.6 KXG47218.1 - 0.026 13.3 0.1 0.032 13.1 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance RIFIN PF02009.16 KXG47218.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Rifin EphA2_TM PF14575.6 KXG47218.1 - 0.034 15.0 0.1 0.066 14.1 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 KXG47218.1 - 0.035 13.9 4.5 0.072 12.9 4.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TrbL PF04610.14 KXG47218.1 - 0.061 13.1 5.7 0.094 12.5 5.7 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein DUF5305 PF17231.2 KXG47218.1 - 0.063 12.7 0.4 0.099 12.0 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Stevor PF17410.2 KXG47218.1 - 0.065 12.8 0.9 0.13 11.8 0.9 1.4 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame DAP10 PF07213.11 KXG47218.1 - 0.072 13.1 0.9 0.21 11.6 0.2 2.0 2 0 0 2 2 2 0 DAP10 membrane protein DUF4366 PF14283.6 KXG47218.1 - 0.072 13.1 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Syndecan PF01034.20 KXG47218.1 - 0.15 12.0 3.6 0.23 11.4 1.6 2.0 2 0 0 2 2 2 0 Syndecan domain DUF2207 PF09972.9 KXG47218.1 - 0.17 10.6 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pheromone PF08015.11 KXG47218.1 - 0.65 11.1 8.0 1.4 10.0 8.0 1.6 1 0 0 1 1 1 0 Fungal mating-type pheromone TPPK_C PF12555.8 KXG47218.1 - 1 9.5 4.2 3 8.0 4.2 1.8 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal NAM-associated PF14303.6 KXG47218.1 - 7.2 7.3 6.4 20 5.9 6.4 1.8 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Xan_ur_permease PF00860.20 KXG47220.1 - 2.8e-24 85.5 28.8 1.3e-13 50.4 14.7 2.3 2 0 0 2 2 2 2 Permease family Beta-lactamase PF00144.24 KXG47223.1 - 2.6e-59 201.1 0.0 3.1e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Epimerase PF01370.21 KXG47224.1 - 0.00064 19.3 0.0 0.0009 18.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family APH PF01636.23 KXG47225.1 - 2.8e-10 40.5 0.1 4.4e-10 39.9 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG47225.1 - 1.2e-05 25.0 0.0 1.8e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase NDUF_B5 PF09781.9 KXG47225.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit zf-CCCH PF00642.24 KXG47226.1 - 0.00038 20.3 9.2 0.0034 17.3 1.6 3.0 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KXG47226.1 - 0.00041 21.0 0.7 0.00041 21.0 0.7 1.9 2 0 0 2 2 2 1 Torus domain zf-CCCH_4 PF18044.1 KXG47226.1 - 0.00044 20.0 3.6 0.00044 20.0 3.6 4.1 5 0 0 5 5 5 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXG47226.1 - 4.6 7.4 14.6 0.21 11.7 6.5 3.1 3 0 0 3 3 3 0 Zinc finger domain Lactamase_B PF00753.27 KXG47227.1 - 2.9e-13 50.3 0.4 7.5e-13 48.9 0.4 1.6 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily GST_N PF02798.20 KXG47228.1 - 6.9e-11 42.3 0.0 1.2e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXG47228.1 - 4.2e-08 33.4 0.0 8.2e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXG47228.1 - 7.3e-06 26.3 0.0 1.1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXG47228.1 - 7.7e-06 26.0 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXG47228.1 - 0.00046 20.3 0.0 0.00077 19.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXG47228.1 - 0.02 14.9 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_76 PF03663.14 KXG47229.1 - 1.4e-45 156.4 11.6 2e-45 155.9 11.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXG47229.1 - 0.00077 18.6 0.3 0.1 11.7 0.0 2.6 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 MFS_1 PF07690.16 KXG47230.1 - 1.1e-19 70.6 32.4 1.1e-19 70.6 32.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily LigB PF02900.18 KXG47231.1 - 2.1e-31 109.0 0.0 2.2e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Amidase PF01425.21 KXG47232.1 - 4.7e-36 124.7 1.4 5.7e-34 117.9 0.7 2.1 2 0 0 2 2 2 2 Amidase FAD_binding_4 PF01565.23 KXG47233.1 - 7.9e-21 74.2 0.8 1.6e-20 73.2 0.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG47233.1 - 2.2e-08 34.1 0.1 4.4e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 KXG47234.1 - 1.2e-57 195.7 0.0 1.6e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_lectin PF07938.12 KXG47236.1 - 8.1e-139 462.1 1.8 9.1e-139 462.0 1.8 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin Alkyl_sulf_dimr PF14863.6 KXG47236.1 - 0.043 14.3 0.1 4.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Git3 PF11710.8 KXG47237.1 - 6.7e-31 107.7 16.1 6.7e-31 107.7 16.1 1.8 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KXG47237.1 - 3.2e-13 49.5 0.1 3.2e-13 49.5 0.1 2.0 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 KXG47237.1 - 3.6e-05 23.0 17.0 5e-05 22.6 17.0 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor OapA_N PF08525.11 KXG47237.1 - 0.0031 17.4 0.4 0.0031 17.4 0.4 2.4 2 0 0 2 2 2 1 Opacity-associated protein A N-terminal motif HhH-GPD PF00730.25 KXG47239.1 - 3.6e-05 24.2 0.0 8.3e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Pneumo_att_G PF05539.11 KXG47239.1 - 0.41 10.2 0.0 0.41 10.2 0.0 3.3 3 1 0 4 4 4 0 Pneumovirinae attachment membrane glycoprotein G G_glu_transpept PF01019.21 KXG47240.1 - 2.9e-166 554.2 0.0 3.3e-166 554.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Fungal_trans_2 PF11951.8 KXG47241.1 - 2.1e-05 23.5 0.1 3.8e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RBM39linker PF15519.6 KXG47243.1 - 0.13 13.4 0.0 0.32 12.1 0.0 1.7 1 1 1 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein MFS_1 PF07690.16 KXG47245.1 - 1.2e-47 162.5 36.0 1.4e-47 162.3 36.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG47245.1 - 3.1e-09 36.2 9.8 3.1e-09 36.2 9.8 2.5 1 1 0 2 2 2 1 Sugar (and other) transporter DUF2583 PF10762.9 KXG47245.1 - 0.15 12.5 2.6 0.3 11.5 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) MFS_1 PF07690.16 KXG47246.1 - 8.2e-19 67.7 58.1 1.4e-15 57.1 31.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG47246.1 - 0.014 13.9 12.6 0.0043 15.5 9.5 1.6 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Aldo_ket_red PF00248.21 KXG47247.1 - 2.6e-62 210.7 0.0 3.2e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_92 PF07971.12 KXG47248.1 - 1.9e-148 495.2 0.2 2.3e-148 495.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXG47248.1 - 1.1e-64 218.6 1.2 1.8e-64 217.9 1.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Evr1_Alr PF04777.13 KXG47249.1 - 2.3e-25 89.0 0.1 3.2e-25 88.5 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family FAD_SOX PF18371.1 KXG47249.1 - 0.04 14.3 0.0 0.057 13.8 0.0 1.3 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase PRKCSH-like PF12999.7 KXG47249.1 - 0.047 13.5 0.5 0.07 12.9 0.5 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like APOBEC4 PF18775.1 KXG47249.1 - 0.081 13.1 0.2 0.19 11.9 0.2 1.6 1 1 1 2 2 2 0 APOBEC4 APOBEC1 PF18769.1 KXG47249.1 - 0.2 11.9 0.1 0.4 10.9 0.1 1.5 1 0 0 1 1 1 0 APOBEC1 zf-LYAR PF08790.11 KXG47250.1 - 5.3e-14 51.8 3.9 5.3e-14 51.8 3.9 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Eapp_C PF10238.9 KXG47250.1 - 0.027 14.5 7.4 0.035 14.2 0.2 3.0 3 0 0 3 3 3 0 E2F-associated phosphoprotein CAP_N PF01213.19 KXG47250.1 - 2.5 7.5 12.6 0.12 11.9 6.3 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal R3H PF01424.22 KXG47251.1 - 1.5e-10 40.9 0.0 2.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 R3H domain Cupin_7 PF12973.7 KXG47252.1 - 2.5e-08 33.7 0.0 3.1e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 ChrR Cupin-like domain adh_short PF00106.25 KXG47253.1 - 9.2e-16 57.9 0.0 1.1e-14 54.3 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG47253.1 - 6.8e-08 32.4 0.0 1.2e-07 31.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG47253.1 - 0.00012 22.0 0.0 0.00071 19.5 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXG47253.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ATP11 PF06644.11 KXG47254.1 - 3.8e-98 328.6 0.0 4.4e-98 328.4 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Hydrolase_4 PF12146.8 KXG47255.1 - 3.2e-16 59.3 0.0 9.8e-10 38.1 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXG47255.1 - 6.6e-11 42.3 0.0 3.1e-06 27.0 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXG47255.1 - 8.3e-06 25.4 0.0 4.9e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXG47255.1 - 1.8e-05 25.5 0.1 0.00051 20.7 0.0 2.3 2 1 1 3 3 3 1 Alpha/beta hydrolase family AXE1 PF05448.12 KXG47255.1 - 2.7e-05 23.0 0.0 0.082 11.6 0.0 2.5 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 KXG47255.1 - 0.00021 21.3 0.0 0.059 13.3 0.0 2.3 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KXG47255.1 - 0.00023 20.9 0.0 0.0012 18.5 0.0 2.1 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 KXG47255.1 - 0.00098 18.7 0.0 0.21 11.1 0.0 2.5 3 0 0 3 3 3 1 Dienelactone hydrolase family DUF818 PF05677.12 KXG47255.1 - 0.001 18.1 0.0 0.0014 17.7 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Esterase PF00756.20 KXG47255.1 - 0.019 14.6 0.0 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Putative esterase Abhydrolase_2 PF02230.16 KXG47255.1 - 0.049 13.4 0.0 1.7 8.4 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 KXG47255.1 - 0.058 13.3 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 KXG47255.1 - 0.074 12.8 0.1 1.6 8.4 0.1 2.3 1 1 0 1 1 1 0 PGAP1-like protein zf-CW PF07496.15 KXG47255.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 CW-type Zinc Finger Proteasome PF00227.26 KXG47256.1 - 1.7e-46 158.2 0.2 1.9e-46 157.9 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.11 KXG47257.1 - 2.8e-39 135.1 1.1 2.8e-24 86.3 0.5 2.7 2 0 0 2 2 2 2 Cyclin Nup192 PF11894.8 KXG47259.1 - 0 1424.6 8.9 0 1424.4 8.9 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DCB PF16213.5 KXG47259.1 - 0.87 9.2 3.7 1.9 8.1 0.9 3.0 2 1 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 PI3_PI4_kinase PF00454.27 KXG47260.1 - 4.1e-52 177.5 0.2 1.4e-51 175.8 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KXG47260.1 - 3.2e-50 170.2 1.5 9.8e-50 168.6 1.5 1.9 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KXG47260.1 - 3.2e-09 36.4 0.2 7.8e-09 35.2 0.2 1.7 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 KXG47260.1 - 6.2e-06 25.7 6.1 1.3e-05 24.6 6.1 1.5 1 0 0 1 1 1 1 FAT domain DUF4015 PF13200.6 KXG47260.1 - 0.061 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain APH PF01636.23 KXG47261.1 - 2.6e-06 27.6 0.2 9.8e-06 25.7 0.0 2.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family ADH_N PF08240.12 KXG47262.1 - 2.4e-26 91.7 0.3 4e-26 91.0 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG47262.1 - 6.3e-21 74.7 0.5 9.7e-21 74.1 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG47262.1 - 0.0055 17.8 0.2 0.011 16.7 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1449 PF07290.11 KXG47262.1 - 0.037 13.6 0.5 0.061 12.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) ADH_N_2 PF16884.5 KXG47262.1 - 0.044 13.7 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase adh_short PF00106.25 KXG47262.1 - 0.2 11.1 1.1 0.86 9.0 0.5 2.1 1 1 1 2 2 2 0 short chain dehydrogenase DUF1365 PF07103.11 KXG47263.1 - 4.4e-22 78.9 0.0 6.7e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) ADH_N PF08240.12 KXG47263.1 - 3e-13 49.6 5.8 2.2e-12 46.8 5.8 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 KXG47263.1 - 1.5e-05 24.4 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KXG47263.1 - 2.7e-05 24.2 0.0 5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXG47263.1 - 0.0079 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain p450 PF00067.22 KXG47264.1 - 4.6e-54 183.9 0.0 7.7e-51 173.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Colicin_immun PF09204.10 KXG47265.1 - 2.1 9.0 4.3 5.3 7.7 0.1 2.9 2 1 0 3 3 3 0 Bacterial self-protective colicin-like immunity RecC_C PF17946.1 KXG47267.1 - 0.027 14.3 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 RecC C-terminal domain FAM176 PF14851.6 KXG47267.1 - 1.2 8.8 4.4 2.4 7.8 4.4 1.5 1 0 0 1 1 1 0 FAM176 family SET PF00856.28 KXG47269.1 - 3.1e-10 40.7 0.0 1.1e-08 35.6 0.0 2.4 1 1 0 1 1 1 1 SET domain SAP PF02037.27 KXG47269.1 - 0.00023 20.8 0.1 0.00043 20.0 0.1 1.5 1 0 0 1 1 1 1 SAP domain TPR_16 PF13432.6 KXG47269.1 - 0.00062 20.4 0.0 0.0018 18.9 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXG47269.1 - 0.0055 17.0 0.1 0.014 15.7 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXG47269.1 - 0.013 15.3 0.2 0.96 9.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXG47269.1 - 0.024 14.3 0.1 0.051 13.3 0.1 1.5 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.17 KXG47269.1 - 0.061 13.5 0.3 1.4 9.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SAF PF08666.12 KXG47269.1 - 0.068 13.8 0.0 5.3 7.8 0.0 2.6 2 0 0 2 2 2 0 SAF domain Aldo_ket_red PF00248.21 KXG47270.1 - 1.7e-67 227.7 0.0 2e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Claudin_3 PF06653.11 KXG47270.1 - 0.06 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like CAMP_factor PF07373.11 KXG47270.1 - 0.1 12.2 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 CAMP factor (Cfa) DAP3 PF10236.9 KXG47271.1 - 2.2e-99 332.6 0.0 2.7e-99 332.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 T2SSE PF00437.20 KXG47271.1 - 0.0068 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein RRS1 PF04939.12 KXG47272.1 - 6.8e-57 191.9 3.8 8.4e-57 191.6 3.8 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.27 KXG47273.1 - 5e-28 97.8 0.0 1.1e-27 96.7 0.0 1.6 2 0 0 2 2 2 1 RhoGAP domain Prenyltrans PF00432.21 KXG47274.1 - 1.1e-50 169.0 6.2 7.7e-11 41.5 0.1 6.5 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KXG47274.1 - 0.00027 20.1 0.0 0.0085 15.2 0.0 2.5 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KXG47274.1 - 0.0012 18.0 0.0 0.21 10.6 0.0 2.8 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain MutS_V PF00488.21 KXG47275.1 - 6.4e-73 244.8 0.1 1.3e-72 243.8 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXG47275.1 - 1.5e-34 119.9 1.8 2.1e-34 119.4 0.6 1.9 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KXG47275.1 - 8.3e-29 100.1 0.1 2.8e-28 98.4 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KXG47275.1 - 3.5e-08 33.8 0.0 1.5e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KXG47275.1 - 0.00035 20.9 0.0 0.0013 19.1 0.0 2.0 1 0 0 1 1 1 1 MutS family domain IV Myc_N PF01056.18 KXG47275.1 - 0.46 10.3 9.9 0.98 9.2 9.9 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_S28e PF01200.18 KXG47276.1 - 8.4e-32 109.0 1.7 9.3e-32 108.8 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e HisG PF01634.18 KXG47277.1 - 4.1e-56 189.4 0.3 7.1e-56 188.6 0.3 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KXG47277.1 - 1.2e-28 99.0 0.3 2.6e-28 98.0 0.3 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 KXG47277.1 - 0.011 15.6 0.2 0.03 14.3 0.1 1.6 1 1 0 1 1 1 0 NMT1/THI5 like Hydrolase_4 PF12146.8 KXG47278.1 - 0.021 14.1 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 KXG47278.1 - 0.065 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 KXG47278.1 - 0.077 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Period_C PF12114.8 KXG47279.1 - 3.5 7.2 8.6 0.12 12.0 2.2 1.7 2 0 0 2 2 2 0 Period protein 2/3C-terminal region ADH_N_2 PF16884.5 KXG47280.1 - 1.6e-23 82.6 0.0 3.7e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KXG47280.1 - 3.2e-19 69.2 0.1 6.6e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG47280.1 - 2.2e-08 35.2 0.0 4.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXG47281.1 - 3.1e-43 147.5 0.3 7.4e-43 146.3 0.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG47281.1 - 2e-42 145.4 0.1 4.9e-42 144.1 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG47281.1 - 3.8e-09 36.7 0.5 1.2e-08 35.1 0.1 1.9 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 KXG47281.1 - 0.0009 19.2 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1776 PF08643.10 KXG47281.1 - 0.0031 16.9 0.0 0.0053 16.2 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.20 KXG47281.1 - 0.0054 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KXG47281.1 - 0.0068 15.6 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXG47281.1 - 0.008 15.6 0.1 0.019 14.3 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_Gly3P_dh_N PF01210.23 KXG47281.1 - 0.1 12.6 0.1 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pkinase PF00069.25 KXG47282.1 - 1.5e-22 80.2 0.0 2.4e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG47282.1 - 3e-16 59.5 0.0 5e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG47282.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Cation_ATPase_C PF00689.21 KXG47283.1 - 2.7e-42 144.5 5.9 2.7e-42 144.5 5.9 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXG47283.1 - 1.7e-39 135.3 2.9 1.7e-39 135.3 2.9 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KXG47283.1 - 3.1e-22 79.9 0.0 7.6e-10 39.4 0.0 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXG47283.1 - 1.1e-20 73.5 0.0 2.1e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXG47283.1 - 4.2e-10 39.2 0.0 1.2e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXG47283.1 - 0.00011 22.0 0.2 0.00026 20.8 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXG47283.1 - 0.0069 16.8 0.0 0.5 10.7 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Phage_holin_3_6 PF07332.11 KXG47283.1 - 0.85 9.7 7.3 3.4 7.7 3.9 2.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III RabGAP-TBC PF00566.18 KXG47284.1 - 2.9e-28 99.0 0.1 5.3e-28 98.1 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KXG47284.1 - 4.7e-08 31.8 0.9 7.5e-08 31.1 0.9 1.4 1 0 0 1 1 1 1 SBE2, cell-wall formation Telomerase_RBD PF12009.8 KXG47285.1 - 9.3e-49 165.0 0.4 2.2e-48 163.8 0.4 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KXG47285.1 - 4.4e-12 46.0 0.0 6.4e-08 32.4 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Imm63 PF15599.6 KXG47285.1 - 0.039 14.4 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 63 RhoGEF PF00621.20 KXG47286.1 - 1.4e-35 123.2 0.0 2.6e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain Peptidase_C48 PF02902.19 KXG47287.1 - 2.4e-15 57.0 0.3 1.7e-14 54.2 0.3 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4951 PF16309.5 KXG47287.1 - 0.0097 15.9 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 Domian of unknown function (DUF4951) Cullin PF00888.22 KXG47288.1 - 2e-183 611.4 0.1 2.5e-183 611.1 0.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KXG47288.1 - 1.4e-23 82.7 0.4 5e-23 80.9 0.4 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.11 KXG47288.1 - 0.24 11.4 1.2 0.97 9.4 0.0 2.7 3 1 1 4 4 4 0 HbrB-like Dak1 PF02733.17 KXG47289.1 - 1.8e-101 339.1 0.0 2.9e-101 338.4 0.0 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KXG47289.1 - 8e-45 152.8 2.2 1.4e-44 152.1 2.2 1.4 1 0 0 1 1 1 1 DAK2 domain LSM PF01423.22 KXG47290.1 - 3.4e-19 68.3 0.1 4.6e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain GATA PF00320.27 KXG47291.1 - 0.00069 19.2 5.2 0.0083 15.7 1.7 2.6 2 0 0 2 2 2 2 GATA zinc finger Rep_fac-A_3 PF08661.11 KXG47292.1 - 6.5e-26 90.7 0.0 7.6e-26 90.5 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1 PF12658.7 KXG47292.1 - 0.0021 18.0 0.1 0.022 14.7 0.1 2.0 1 1 0 1 1 1 1 Telomere capping, CST complex subunit MFAP1 PF06991.11 KXG47293.1 - 2e-67 227.2 31.0 2e-67 227.2 31.0 3.4 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing DUF5494 PF17598.2 KXG47293.1 - 4.1 7.6 8.1 11 6.2 8.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5494) TRAPP PF04051.16 KXG47294.1 - 1.2e-37 128.9 0.0 1.5e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component NAD_kinase PF01513.21 KXG47295.1 - 3.2e-72 243.2 0.0 4.6e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Las1 PF04031.13 KXG47296.1 - 3.1e-46 157.3 0.1 5.3e-46 156.5 0.1 1.4 1 0 0 1 1 1 1 Las1-like Lactamase_B PF00753.27 KXG47296.1 - 2.9e-21 76.4 0.7 2.2e-20 73.5 0.7 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HAGH_C PF16123.5 KXG47296.1 - 8.4e-20 71.1 0.2 2e-19 69.9 0.2 1.6 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B_2 PF12706.7 KXG47296.1 - 0.0013 18.3 0.7 0.0077 15.8 0.7 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.20 KXG47296.1 - 0.082 12.4 0.2 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family UPF0688 PF15772.5 KXG47297.1 - 0.012 15.9 0.8 0.017 15.4 0.8 1.1 1 0 0 1 1 1 0 UPF0688 family SnoaL_4 PF13577.6 KXG47298.1 - 2.8e-19 69.5 0.1 3.4e-19 69.2 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF3244 PF11589.8 KXG47298.1 - 0.061 13.4 0.0 7.1 6.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3244) Lumazine_bd_2 PF12893.7 KXG47298.1 - 0.26 12.0 1.7 0.72 10.6 0.0 2.3 2 1 1 3 3 3 0 Putative lumazine-binding Methyltransf_3 PF01596.17 KXG47299.1 - 6.7e-25 87.5 0.0 8.6e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KXG47299.1 - 1.6e-11 45.1 0.0 3e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KXG47299.1 - 0.00025 21.0 0.0 0.00039 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TrmK PF04816.12 KXG47299.1 - 0.00042 19.9 0.0 0.00064 19.3 0.0 1.2 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase PCMT PF01135.19 KXG47299.1 - 0.0035 17.1 0.1 0.01 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KXG47299.1 - 0.0088 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KXG47299.1 - 0.013 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KXG47299.1 - 0.042 14.5 0.0 0.14 12.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.10 KXG47299.1 - 0.098 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GCD14 PF08704.10 KXG47299.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit CmcI PF04989.12 KXG47299.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase Methyltransf_31 PF13847.6 KXG47299.1 - 0.13 12.1 0.0 0.64 9.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 KXG47300.1 - 7.5e-49 166.5 27.9 7.5e-49 166.5 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 KXG47301.1 - 2.6e-22 79.2 0.0 3.3e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG47301.1 - 3e-21 76.1 0.0 3.5e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXG47301.1 - 0.00019 21.0 0.0 0.00032 20.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXG47301.1 - 0.015 15.2 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 KR domain Questin_oxidase PF14027.6 KXG47302.1 - 3.8e-76 256.8 0.0 4.5e-76 256.6 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like FSH1 PF03959.13 KXG47303.1 - 9.9e-30 103.8 0.0 2.3e-29 102.6 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF5423 PF17461.2 KXG47304.1 - 1.4 7.7 4.0 2.1 7.1 4.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5423) MFS_1 PF07690.16 KXG47305.1 - 2.7e-36 125.3 38.3 3.7e-36 124.8 38.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG47305.1 - 9.8e-13 47.8 10.2 9.8e-13 47.8 10.2 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KXG47305.1 - 2.5e-09 36.1 4.5 4.9e-09 35.2 4.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Wzz PF02706.15 KXG47305.1 - 0.39 11.0 2.2 1.7 9.0 0.1 2.9 2 0 0 2 2 2 0 Chain length determinant protein ketoacyl-synt PF00109.26 KXG47306.1 - 2.2e-80 269.9 0.0 4.8e-80 268.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KXG47306.1 - 1.9e-71 240.6 0.3 5.2e-70 235.9 0.0 2.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KXG47306.1 - 1.4e-36 126.6 0.0 3.1e-36 125.5 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXG47306.1 - 2.8e-32 111.2 0.9 7e-32 109.9 0.9 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KXG47306.1 - 1.2e-23 83.6 0.0 2.3e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KXG47306.1 - 1.6e-19 70.0 9.1 2.5e-10 40.6 1.8 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 KXG47306.1 - 7.6e-13 48.3 0.0 1.5e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KXG47306.1 - 4.9e-07 30.2 0.1 2.5e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 KXG47306.1 - 2.8e-06 27.0 0.0 5.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 KXG47306.1 - 0.00011 21.7 0.0 0.00028 20.3 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.15 KXG47306.1 - 0.0005 19.3 0.0 0.028 13.5 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KXG47306.1 - 0.029 14.3 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 KR domain FAD_binding_3 PF01494.19 KXG47307.1 - 3.9e-71 240.1 0.0 5.5e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXG47307.1 - 2.2e-08 34.1 0.2 4.6e-05 23.2 0.1 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG47307.1 - 0.00066 19.0 0.0 0.0022 17.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG47307.1 - 0.0012 18.2 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG47307.1 - 0.0015 18.7 0.1 0.0054 16.9 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXG47307.1 - 0.0017 18.9 0.2 0.0045 17.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXG47307.1 - 0.007 16.6 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_2 PF00890.24 KXG47307.1 - 0.027 13.6 0.5 0.058 12.5 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 KXG47307.1 - 0.027 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 KXG47307.1 - 0.03 13.6 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KXG47307.1 - 0.042 12.9 0.1 0.072 12.1 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 KXG47307.1 - 0.083 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 KXG47307.1 - 0.089 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PAS_8 PF13188.7 KXG47307.1 - 0.13 12.3 0.0 0.84 9.7 0.0 2.5 1 1 0 1 1 1 0 PAS domain p450 PF00067.22 KXG47308.1 - 1.1e-73 248.5 0.0 1.4e-73 248.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KXG47309.1 - 1.9e-10 40.7 6.1 3.5e-10 39.8 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.10 KXG47309.1 - 5.4e-05 22.8 1.5 8.3e-05 22.2 0.1 1.9 2 0 0 2 2 2 1 Aflatoxin regulatory protein DUF1264 PF06884.11 KXG47310.1 - 3.2e-77 257.9 0.0 4.1e-77 257.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Peptidase_S26 PF10502.9 KXG47310.1 - 1.2e-05 25.1 0.0 0.0016 18.2 0.0 2.4 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 KXG47310.1 - 0.00068 19.6 0.1 0.0015 18.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase S24-like PBP PF01161.20 KXG47311.1 - 1.4e-09 38.4 0.0 2.3e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L4 PF00573.22 KXG47312.1 - 2.3e-46 157.9 0.0 3.3e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family ECH_2 PF16113.5 KXG47313.1 - 7.2e-131 436.6 0.0 9.7e-131 436.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KXG47313.1 - 3.5e-24 85.5 0.1 1.6e-23 83.3 0.0 1.9 2 1 1 3 3 3 1 Enoyl-CoA hydratase/isomerase FPN1 PF06963.12 KXG47314.1 - 3.6e-122 408.1 28.7 1e-105 353.8 22.5 2.9 1 1 1 2 2 2 2 Ferroportin1 (FPN1) Fungal_trans_2 PF11951.8 KXG47315.1 - 4.6e-13 48.7 0.0 7.1e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.23 KXG47316.1 - 1.7e-69 234.6 0.0 2.2e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KXG47316.1 - 0.094 13.0 0.0 0.23 11.7 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4976) bZIP_1 PF00170.21 KXG47317.1 - 3.5e-09 36.6 11.7 3.5e-09 36.6 11.7 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KXG47317.1 - 1e-05 25.5 11.9 1e-05 25.5 11.9 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXG47317.1 - 0.01 16.3 9.6 0.011 16.2 8.2 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor RGS12_us1 PF16613.5 KXG47317.1 - 0.21 11.9 4.9 1.3 9.4 1.4 2.3 2 0 0 2 2 2 0 Unstructured region of RGS12 DUF349 PF03993.12 KXG47317.1 - 8.3 6.8 11.3 0.38 11.1 5.6 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) RhoGAP PF00620.27 KXG47318.1 - 6.8e-06 26.0 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CBS PF00571.28 KXG47319.1 - 3.5e-22 78.6 6.0 4e-09 36.8 0.1 4.3 4 0 0 4 4 4 3 CBS domain SRR1 PF07985.12 KXG47320.1 - 1.2e-08 34.9 0.0 2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 SRR1 SRR1 PF07985.12 KXG47321.1 - 1.1e-10 41.3 0.0 2.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 SRR1 Sad1_UNC PF07738.13 KXG47322.1 - 1.1e-12 48.2 0.0 3.2e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal WD40 PF00400.32 KXG47323.1 - 2.3e-28 97.9 13.5 8.5e-06 26.4 1.3 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 KXG47323.1 - 1.9e-08 33.4 0.9 0.064 11.9 0.1 4.8 3 1 2 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXG47323.1 - 8.3e-06 26.0 0.1 0.18 12.1 0.0 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Seryl_tRNA_N PF02403.22 KXG47323.1 - 0.073 13.3 0.6 0.17 12.1 0.1 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF5046 PF16465.5 KXG47323.1 - 0.097 12.1 0.2 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) APG6_N PF17675.1 KXG47323.1 - 0.21 12.1 3.0 0.38 11.3 3.0 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region BCIP PF13862.6 KXG47325.1 - 9.3e-75 250.9 0.2 1.2e-74 250.5 0.2 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Mannosyl_trans3 PF11051.8 KXG47328.1 - 1.5e-58 198.4 0.0 2.9e-36 125.3 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative ANAPC15 PF15243.6 KXG47328.1 - 0.13 12.7 0.0 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Fungal_trans_2 PF11951.8 KXG47329.1 - 8.4e-52 176.3 0.1 1.5e-51 175.4 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG47329.1 - 2.1e-05 24.5 5.9 4.9e-05 23.4 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.9 KXG47330.1 - 2.5 7.2 7.3 3.2 6.8 7.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ion_trans_2 PF07885.16 KXG47331.1 - 5.1e-29 100.1 27.2 5.1e-17 61.6 5.8 3.3 3 1 1 4 4 4 2 Ion channel Ion_trans PF00520.31 KXG47331.1 - 0.0029 16.9 19.2 0.027 13.7 3.3 3.2 3 0 0 3 3 3 3 Ion transport protein DUF4083 PF13314.6 KXG47331.1 - 1.5 8.8 4.9 1.7 8.7 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Macro_2 PF14519.6 KXG47332.1 - 0.0025 17.2 0.0 0.0031 16.9 0.0 1.1 1 0 0 1 1 1 1 Macro-like domain adh_short PF00106.25 KXG47333.1 - 5.8e-07 29.2 0.2 6.9e-07 28.9 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG47333.1 - 8.3e-06 25.5 0.3 9.7e-06 25.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG47333.1 - 0.0035 17.3 0.1 0.0041 17.1 0.1 1.0 1 0 0 1 1 1 1 KR domain DUF1275 PF06912.11 KXG47334.1 - 3e-46 157.8 14.7 3.5e-46 157.6 14.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1422 PF07226.11 KXG47334.1 - 0.16 11.9 3.1 1.6 8.8 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) IF-2B PF01008.17 KXG47335.1 - 5.6e-76 255.4 0.1 7.3e-76 255.1 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Kinesin PF00225.23 KXG47336.1 - 9.1e-113 376.6 0.0 1.4e-112 375.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXG47336.1 - 2.5e-27 95.6 0.1 1.7e-26 93.0 0.0 2.4 3 0 0 3 3 3 1 Microtubule binding Spc7 PF08317.11 KXG47336.1 - 0.0049 15.8 12.3 0.01 14.8 12.3 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein ZapB PF06005.12 KXG47336.1 - 0.042 14.3 7.3 11 6.6 7.3 2.9 1 1 0 1 1 1 0 Cell division protein ZapB RE_HindIII PF09518.10 KXG47336.1 - 0.1 11.8 6.1 0.18 11.0 6.1 1.3 1 0 0 1 1 1 0 HindIII restriction endonuclease DUF1460 PF07313.12 KXG47336.1 - 0.22 10.9 1.6 0.38 10.1 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) HlyD_2 PF12700.7 KXG47336.1 - 0.27 10.0 4.5 0.4 9.4 4.5 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Bacillus_HBL PF05791.11 KXG47336.1 - 0.34 10.7 0.1 0.34 10.7 0.1 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TBCC_N PF16752.5 KXG47336.1 - 2.8 8.4 11.5 18 5.8 11.5 2.3 1 1 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain V_ATPase_I PF01496.19 KXG47336.1 - 3.4 5.5 8.9 5.8 4.7 8.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_M32 PF02074.15 KXG47336.1 - 6.5 5.4 12.8 1.8 7.3 8.3 1.9 2 0 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase Apc13p PF05839.11 KXG47337.1 - 6.2e-17 61.6 0.1 7.9e-16 58.0 0.0 2.2 2 1 0 2 2 2 1 Apc13p protein Pol_alpha_B_N PF08418.10 KXG47338.1 - 4e-78 262.8 0.0 5.7e-78 262.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KXG47338.1 - 3.2e-38 131.2 0.0 4.6e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CRAL_TRIO PF00650.20 KXG47339.1 - 2.9e-36 124.6 0.0 4e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXG47339.1 - 8e-17 61.2 0.3 1.6e-16 60.2 0.3 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXG47339.1 - 0.023 14.9 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain NAD_binding_6 PF08030.12 KXG47340.1 - 8.1e-22 78.0 0.0 1.2e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KXG47340.1 - 9.2e-19 67.8 11.1 9.2e-19 67.8 11.1 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXG47340.1 - 1e-09 38.4 0.0 2.7e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain FTR1 PF03239.14 KXG47341.1 - 1.3e-71 241.3 4.7 1.5e-71 241.1 4.7 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF1043 PF06295.12 KXG47341.1 - 0.12 12.4 1.2 15 5.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) ThrE PF06738.12 KXG47341.1 - 0.39 10.1 6.8 4.7 6.5 1.4 2.3 2 0 0 2 2 2 0 Putative threonine/serine exporter LptF_LptG PF03739.14 KXG47341.1 - 0.75 8.6 5.4 0.37 9.6 3.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG DUF2232 PF09991.9 KXG47341.1 - 1 8.4 8.6 0.18 11.0 3.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) DUF3180 PF11377.8 KXG47341.1 - 5.6 7.1 12.0 2 8.6 0.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) Cu-oxidase_2 PF07731.14 KXG47342.1 - 2.2e-47 160.2 6.2 2e-41 140.9 0.3 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXG47342.1 - 6e-41 139.2 6.3 4.8e-39 133.1 1.4 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KXG47342.1 - 1.3e-34 119.7 1.4 4e-32 111.5 0.3 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.6 KXG47342.1 - 0.08 13.1 0.0 30 4.8 0.0 3.4 4 0 0 4 4 4 0 Cupredoxin-like domain Kinesin PF00225.23 KXG47343.1 - 2.9e-92 309.1 0.1 2.9e-92 309.1 0.1 2.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXG47343.1 - 5.2e-22 78.4 0.0 2.2e-17 63.4 0.0 3.2 1 1 1 2 2 2 2 Microtubule binding DUF641 PF04859.12 KXG47343.1 - 0.0076 16.6 3.9 0.0076 16.6 3.9 10.5 5 3 5 10 10 10 1 Plant protein of unknown function (DUF641) SAP PF02037.27 KXG47343.1 - 6.4 6.6 6.7 5.2 6.9 0.0 3.9 4 0 0 4 4 4 0 SAP domain Glycos_transf_1 PF00534.20 KXG47344.1 - 7e-31 107.1 0.0 5.9e-29 100.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXG47344.1 - 2.5e-17 63.4 0.1 2.4e-16 60.2 0.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KXG47344.1 - 5.2e-12 46.3 0.1 3.2e-10 40.6 0.1 2.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXG47344.1 - 3.6e-08 34.0 1.8 8.3e-08 32.8 1.8 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KXG47344.1 - 0.0067 16.8 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 PKS_DE PF18369.1 KXG47344.1 - 0.16 12.5 0.7 2.6 8.7 0.1 2.9 3 0 0 3 3 3 0 Polyketide synthase dimerisation element domain ERCC4 PF02732.15 KXG47345.1 - 6.8e-35 120.6 0.0 1.2e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain Atg14 PF10186.9 KXG47345.1 - 2.9 6.9 10.0 6 5.9 10.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 IPK PF03770.16 KXG47346.1 - 2.5e-58 197.2 0.0 4.2e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase MFS_1 PF07690.16 KXG47346.1 - 1.2e-18 67.2 16.4 2.2e-18 66.3 16.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KXG47346.1 - 0.00022 20.8 3.9 0.00022 20.8 3.9 1.9 2 0 0 2 2 2 1 Nodulin-like DUF997 PF06196.12 KXG47346.1 - 2.5 8.1 5.8 7.2 6.7 2.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Amidase PF01425.21 KXG47347.1 - 0.12 11.3 4.2 0.17 10.8 4.2 1.2 1 0 0 1 1 1 0 Amidase LMBR1 PF04791.16 KXG47347.1 - 0.41 9.5 7.9 0.53 9.1 7.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4638 PF15472.6 KXG47347.1 - 1 9.0 13.6 1.7 8.3 13.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Peptidase_S49_N PF08496.10 KXG47347.1 - 1.1 9.3 10.1 2.3 8.3 10.1 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RED_N PF07808.13 KXG47347.1 - 1.8 8.1 20.7 0.67 9.5 17.0 2.0 2 0 0 2 2 2 0 RED-like protein N-terminal region SLC12 PF03522.15 KXG47347.1 - 1.8 7.5 19.0 2.9 6.8 19.0 1.5 1 0 0 1 1 1 0 Solute carrier family 12 Serinc PF03348.15 KXG47347.1 - 2.3 7.1 6.9 3 6.7 6.9 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4820 PF16091.5 KXG47347.1 - 4.5 6.6 12.5 0.89 8.9 7.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF853 PF05872.12 KXG47347.1 - 4.5 5.7 11.3 6.8 5.2 11.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) SID-1_RNA_chan PF13965.6 KXG47347.1 - 4.9 5.4 6.6 6.3 5.1 6.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CSG2 PF16965.5 KXG47347.1 - 5.3 5.9 7.5 7.6 5.4 7.5 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Cdh1_DBD_1 PF18196.1 KXG47347.1 - 6.7 7.1 8.9 7.3 6.9 7.5 1.8 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Connexin PF00029.19 KXG47347.1 - 9.3 5.9 16.2 0.79 9.4 11.3 1.7 2 0 0 2 2 2 0 Connexin Miga PF10265.9 KXG47347.1 - 9.5 5.1 13.0 13 4.6 13.0 1.1 1 0 0 1 1 1 0 Mitoguardin ABC2_membrane_2 PF12679.7 KXG47347.1 - 9.9 5.3 5.2 13 5.0 5.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein MscL PF01741.18 KXG47349.1 - 3.4e-12 46.7 0.2 4.5e-12 46.3 0.2 1.2 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf-ribbon_3 PF13248.6 KXG47349.1 - 0.0015 17.9 1.0 0.0023 17.2 1.0 1.3 1 0 0 1 1 1 1 zinc-ribbon domain UPF0547 PF10571.9 KXG47349.1 - 0.016 15.3 1.4 0.027 14.6 1.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-Di19 PF05605.12 KXG47349.1 - 0.069 13.5 0.3 0.12 12.7 0.3 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding ABC_tran PF00005.27 KXG47350.1 - 2.2e-23 83.3 0.0 1.2e-11 45.2 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXG47350.1 - 2.7e-10 40.5 5.1 2.3e-05 24.3 0.2 3.0 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KXG47350.1 - 4.6e-07 30.0 0.1 0.0047 17.1 0.1 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KXG47350.1 - 0.0021 17.8 0.1 0.0049 16.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KXG47350.1 - 0.006 17.1 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXG47350.1 - 0.017 15.4 0.1 0.18 12.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 KXG47350.1 - 0.019 14.7 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 KXG47350.1 - 0.019 14.4 0.0 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 KXG47350.1 - 0.09 12.0 0.0 0.33 10.1 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 KXG47350.1 - 0.12 12.3 0.3 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Peptidase_S28 PF05577.12 KXG47350.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 AAA_24 PF13479.6 KXG47350.1 - 0.19 11.5 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXG47350.1 - 0.21 11.3 0.0 0.69 9.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain CoA_transf_3 PF02515.17 KXG47351.1 - 4.4e-42 144.5 0.4 1e-40 140.0 0.1 2.2 2 0 0 2 2 2 2 CoA-transferase family III Abhydrolase_6 PF12697.7 KXG47352.1 - 9e-10 39.5 0.3 2.6e-09 38.0 0.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG47352.1 - 0.043 13.4 0.1 0.11 12.1 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Response_reg PF00072.24 KXG47353.1 - 1.6e-23 83.0 0.3 5.1e-23 81.4 0.3 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KXG47353.1 - 4.6e-16 59.3 0.1 2.4e-15 57.0 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KXG47353.1 - 3.5e-09 36.6 2.1 5.2e-09 36.0 0.2 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KXG47353.1 - 0.021 15.1 0.0 0.061 13.6 0.0 1.9 1 0 0 1 1 1 0 GAF domain GAF PF01590.26 KXG47353.1 - 0.042 14.5 0.0 0.3 11.7 0.0 2.4 2 0 0 2 2 2 0 GAF domain GAF_3 PF13492.6 KXG47353.1 - 0.1 12.9 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 GAF domain SdpI PF13630.6 KXG47354.1 - 0.023 14.8 0.9 0.023 14.8 0.9 2.7 1 1 1 2 2 2 0 SdpI/YhfL protein family FtsX PF02687.21 KXG47354.1 - 0.11 13.0 0.3 0.11 13.0 0.3 2.7 2 0 0 2 2 2 0 FtsX-like permease family CcmF_C PF16327.5 KXG47354.1 - 3.9 6.7 11.1 0.12 11.6 4.0 1.8 2 0 0 2 2 2 0 Cytochrome c-type biogenesis protein CcmF C-terminal AMP-binding PF00501.28 KXG47355.1 - 1.3e-57 195.4 0.0 1.7e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG47355.1 - 1.7e-16 60.9 0.2 4.8e-16 59.5 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ferritin_2 PF13668.6 KXG47357.1 - 5.6e-15 55.7 0.0 1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain DUF3658 PF12395.8 KXG47357.1 - 0.11 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function adh_short PF00106.25 KXG47358.1 - 2.4e-35 121.8 0.2 5.9e-35 120.5 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG47358.1 - 3.7e-32 111.8 0.4 1.7e-30 106.3 0.4 2.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG47358.1 - 6.5e-08 32.7 2.0 1.2e-07 31.8 0.4 2.1 3 0 0 3 3 3 1 KR domain Polysacc_synt_2 PF02719.15 KXG47358.1 - 0.00037 19.7 0.2 0.00077 18.7 0.2 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KXG47358.1 - 0.0027 18.0 0.1 0.0056 16.9 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KXG47358.1 - 0.0061 15.6 0.4 0.015 14.3 0.1 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KXG47358.1 - 0.023 14.8 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.10 KXG47358.1 - 0.036 13.4 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DIOX_N PF14226.6 KXG47359.1 - 5.4e-25 88.5 0.0 1e-24 87.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG47359.1 - 5.5e-18 65.3 0.0 1e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SGL PF08450.12 KXG47360.1 - 8.3e-05 22.3 0.2 0.0002 21.0 0.1 1.5 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KXG47360.1 - 0.12 12.4 1.1 6.9 6.9 0.0 3.4 3 0 0 3 3 3 0 NHL repeat Lactonase PF10282.9 KXG47360.1 - 0.14 11.4 0.0 0.91 8.7 0.0 2.2 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller EthD PF07110.11 KXG47361.1 - 0.00016 22.8 0.0 0.00021 22.4 0.0 1.1 1 0 0 1 1 1 1 EthD domain Amidohydro_2 PF04909.14 KXG47362.1 - 1e-25 91.2 0.0 2.6e-25 89.8 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase Mei4 PF13971.6 KXG47363.1 - 0.0066 16.0 3.9 0.011 15.2 0.0 2.3 2 1 0 2 2 2 1 Meiosis-specific protein Mei4 OspD PF03207.13 KXG47363.1 - 0.082 12.2 7.3 0.0088 15.4 2.9 1.6 2 0 0 2 2 2 0 Borrelia outer surface protein D (OspD) DUF1676 PF07898.13 KXG47363.1 - 1.1 9.3 6.2 0.62 10.1 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1676) DnaJ PF00226.31 KXG47364.1 - 1.6e-19 69.8 1.2 1.6e-19 69.8 1.2 2.2 3 0 0 3 3 3 1 DnaJ domain RRM_1 PF00076.22 KXG47364.1 - 1.5 8.7 3.9 0.72 9.7 0.2 2.5 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GCV_T PF01571.21 KXG47365.1 - 2.5e-05 23.8 0.0 4.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Helo_like_N PF17111.5 KXG47366.1 - 5.8e-05 22.6 1.6 8.8e-05 22.0 1.6 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KXG47366.1 - 0.047 13.9 0.7 0.084 13.1 0.6 1.6 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Rx_N PF18052.1 KXG47366.1 - 0.052 13.8 0.4 0.12 12.6 0.4 1.7 1 0 0 1 1 1 0 Rx N-terminal domain WD40 PF00400.32 KXG47367.1 - 1.8e-39 133.0 20.1 9.4e-06 26.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG47367.1 - 7.7e-16 58.2 0.0 0.00042 20.6 0.1 5.2 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXG47367.1 - 7e-05 22.8 0.0 0.11 12.3 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KXG47367.1 - 0.00073 19.0 0.0 0.044 13.1 0.0 3.0 2 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 KXG47367.1 - 0.031 13.2 0.2 15 4.5 0.0 3.6 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-MYND PF01753.18 KXG47368.1 - 1.8e-07 31.1 20.7 3.8e-07 30.1 20.7 1.6 1 0 0 1 1 1 1 MYND finger zf-TAZ PF02135.16 KXG47368.1 - 7.8 7.0 13.3 14 6.2 13.3 1.4 1 0 0 1 1 1 0 TAZ zinc finger DIOX_N PF14226.6 KXG47369.1 - 1.7e-19 70.7 0.0 2.6e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG47369.1 - 9.5e-13 48.5 0.0 3.1e-12 46.8 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.8 KXG47370.1 - 4.3e-78 261.9 0.0 8e-78 261.0 0.0 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KXG47370.1 - 5.3e-30 103.6 0.0 1.2e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.18 KXG47370.1 - 3.6e-05 24.0 0.0 7.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KXG47370.1 - 5.4e-05 23.6 0.0 0.0001 22.7 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain DUF3665 PF12427.8 KXG47370.1 - 0.13 11.9 0.1 0.28 10.9 0.1 1.5 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Thioredoxin PF00085.20 KXG47371.1 - 6e-59 196.4 0.2 7.5e-29 99.8 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin ERp29 PF07749.12 KXG47371.1 - 2.6e-22 79.5 0.6 6.3e-22 78.3 0.6 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KXG47371.1 - 1.3e-18 67.4 0.0 5.8e-08 33.2 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KXG47371.1 - 6.6e-15 55.2 0.0 4.9e-07 29.4 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KXG47371.1 - 1e-09 38.4 0.0 0.00024 21.2 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KXG47371.1 - 6.1e-08 32.9 0.0 0.0027 18.0 0.0 3.4 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 KXG47371.1 - 1.3e-07 31.6 0.0 0.012 15.5 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family TraF PF13728.6 KXG47371.1 - 2e-06 27.8 0.0 0.0022 17.9 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 KXG47371.1 - 2.8e-05 23.9 0.1 0.075 12.8 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.6 KXG47371.1 - 0.00011 22.2 0.8 0.42 10.5 0.0 3.5 3 1 1 4 4 4 1 Thioredoxin-like domain Glutaredoxin PF00462.24 KXG47371.1 - 0.0005 20.2 0.3 1.2 9.4 0.0 3.2 3 1 0 3 3 3 2 Glutaredoxin HyaE PF07449.11 KXG47371.1 - 0.00064 19.7 0.0 0.34 10.9 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KXG47371.1 - 0.002 17.9 0.0 0.56 10.0 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin DSBA PF01323.20 KXG47371.1 - 0.014 15.2 1.1 5.2 6.8 0.0 3.8 3 2 1 4 4 4 0 DSBA-like thioredoxin domain DUF836 PF05768.14 KXG47371.1 - 0.041 14.3 0.0 0.8 10.2 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) SLATT_4 PF18186.1 KXG47371.1 - 0.1 12.2 0.3 0.18 11.4 0.3 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 Thioredoxin_4 PF13462.6 KXG47371.1 - 0.13 12.4 2.0 19 5.4 0.3 3.7 2 2 1 3 3 3 0 Thioredoxin HSBP1 PF06825.12 KXG47372.1 - 2.9e-18 65.5 0.2 4.1e-18 65.0 0.2 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.9 KXG47372.1 - 0.00077 19.3 0.8 0.011 15.6 0.8 2.1 1 1 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin Baculo_PEP_C PF04513.12 KXG47372.1 - 0.0066 16.5 0.3 0.0083 16.2 0.3 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KXG47372.1 - 0.013 15.4 0.2 0.016 15.1 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.12 KXG47372.1 - 0.018 15.5 0.1 0.029 14.8 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.6 KXG47372.1 - 0.048 14.1 0.0 0.065 13.6 0.0 1.1 1 0 0 1 1 1 0 Snapin/Pallidin Vinculin PF01044.19 KXG47372.1 - 0.062 11.5 0.1 0.066 11.4 0.1 1.0 1 0 0 1 1 1 0 Vinculin family Prp19 PF08606.11 KXG47372.1 - 0.062 13.3 0.1 0.093 12.7 0.1 1.3 1 0 0 1 1 1 0 Prp19/Pso4-like ABC_tran_CTD PF16326.5 KXG47372.1 - 0.22 11.8 1.1 0.96 9.7 0.5 1.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain Ebp2 PF05890.12 KXG47373.1 - 3.7e-93 312.0 15.0 3.7e-93 312.0 15.0 2.0 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Myc_N PF01056.18 KXG47373.1 - 0.78 9.6 17.0 0.056 13.3 9.9 2.1 2 0 0 2 2 2 0 Myc amino-terminal region SRP-alpha_N PF04086.13 KXG47373.1 - 2.6 7.9 35.8 3.9 7.3 18.7 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal TruB_N PF01509.18 KXG47374.1 - 1.6e-45 155.1 0.0 4.7e-45 153.6 0.0 1.8 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KXG47374.1 - 1.1e-06 28.6 0.0 2.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Baculo_PP31 PF05311.11 KXG47374.1 - 0.0092 15.5 0.1 0.023 14.2 0.0 1.6 2 1 0 2 2 2 1 Baculovirus 33KDa late protein (PP31) Metallophos PF00149.28 KXG47375.1 - 7e-12 46.3 1.0 1.5e-11 45.2 0.4 1.8 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXG47375.1 - 1.1e-06 28.9 0.0 6.5e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DNMT1-RFD PF12047.8 KXG47376.1 - 4.3e-05 23.6 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Ycf1 PF05758.12 KXG47376.1 - 0.091 10.6 0.7 0.13 10.1 0.7 1.1 1 0 0 1 1 1 0 Ycf1 OHCU_decarbox PF09349.10 KXG47377.1 - 5.5e-43 147.1 0.0 8.7e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 OHCU decarboxylase WD40 PF00400.32 KXG47377.1 - 4.5e-16 59.0 0.1 0.0027 18.5 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG47377.1 - 0.00074 19.8 0.0 2.9 8.3 0.0 4.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain EthD PF07110.11 KXG47378.1 - 9.4e-12 45.9 0.1 1.2e-11 45.6 0.1 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KXG47378.1 - 0.0081 16.6 0.3 0.03 14.8 0.3 1.8 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase RII_binding_1 PF10522.9 KXG47379.1 - 0.13 12.5 0.1 5.3 7.5 0.0 2.6 2 0 0 2 2 2 0 RII binding domain SRP9-21 PF05486.12 KXG47380.1 - 1.8e-30 105.2 2.1 2.9e-30 104.5 2.1 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribonuc_red_sm PF00268.21 KXG47381.1 - 9.1e-123 409.1 0.5 1.1e-122 408.9 0.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain RE_XcyI PF09571.10 KXG47381.1 - 0.021 14.1 0.1 3.6 6.8 0.0 2.2 2 0 0 2 2 2 0 XcyI restriction endonuclease Mito_carr PF00153.27 KXG47382.1 - 6.6e-54 179.8 4.0 1.2e-18 66.8 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MotA_ExbB PF01618.16 KXG47382.1 - 0.097 12.4 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family WD40 PF00400.32 KXG47383.1 - 4.1e-13 49.6 4.6 0.0002 22.1 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG47383.1 - 1.1e-06 28.9 0.0 0.057 13.7 0.0 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KXG47383.1 - 0.048 12.0 0.0 0.075 11.3 0.0 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KXG47383.1 - 0.081 12.9 0.2 53 3.9 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat TruB_C PF09142.11 KXG47383.1 - 0.1 12.4 1.0 0.44 10.4 0.1 2.4 3 0 0 3 3 3 0 tRNA Pseudouridine synthase II, C terminal DUF1308 PF07000.11 KXG47384.1 - 4.7e-10 39.6 0.0 3.3e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 KXG47384.1 - 0.017 14.4 0.0 1.2 8.4 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5614) ASD2 PF08687.11 KXG47384.1 - 0.039 13.5 0.3 0.076 12.6 0.3 1.4 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 MmgE_PrpD PF03972.14 KXG47384.1 - 0.22 10.0 0.0 0.33 9.4 0.0 1.2 1 0 0 1 1 1 0 MmgE/PrpD family Lung_7-TM_R PF06814.13 KXG47385.1 - 1.4e-67 228.0 14.3 1.7e-67 227.8 14.3 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor CTU2 PF10288.9 KXG47386.1 - 6.8e-11 42.4 3.1 1.2e-08 35.2 0.0 2.9 2 1 1 3 3 3 2 Cytoplasmic tRNA 2-thiolation protein 2 FYVE PF01363.21 KXG47386.1 - 0.016 15.3 2.6 0.69 10.1 0.1 2.3 2 0 0 2 2 2 0 FYVE zinc finger DUF1289 PF06945.13 KXG47386.1 - 0.26 11.1 2.6 0.35 10.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) DUF4112 PF13430.6 KXG47387.1 - 5.5e-34 116.6 0.5 7.1e-34 116.2 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DCP2 PF05026.13 KXG47388.1 - 8.7e-31 106.1 1.9 1.5e-30 105.3 1.9 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KXG47388.1 - 8.9e-18 64.6 0.1 1.7e-17 63.7 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain APH PF01636.23 KXG47389.1 - 7.1e-17 62.1 0.1 1.5e-16 61.1 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG47389.1 - 0.00049 19.8 0.0 0.00075 19.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KXG47389.1 - 0.066 12.6 0.0 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.22 KXG47389.1 - 0.1 12.2 0.2 3.4 7.2 0.1 2.1 2 0 0 2 2 2 0 RIO1 family PhoH PF02562.16 KXG47389.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Phosducin PF02114.16 KXG47390.1 - 1.5e-15 56.9 0.0 4.9e-14 51.9 0.0 2.1 1 1 0 1 1 1 1 Phosducin YEATS PF03366.16 KXG47391.1 - 3e-19 68.8 0.2 5.5e-19 67.9 0.2 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KXG47391.1 - 5.4e-06 26.5 0.1 1e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Ran_BP1 PF00638.18 KXG47392.1 - 3.7e-48 162.8 2.4 3.7e-48 162.8 2.4 1.6 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 KXG47392.1 - 3e-05 23.9 0.6 0.00016 21.6 0.6 1.9 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 KXG47392.1 - 0.0012 19.1 0.1 0.0018 18.5 0.1 1.3 1 0 0 1 1 1 1 VID27 PH-like domain CDC27 PF09507.10 KXG47392.1 - 0.33 10.3 21.4 0.45 9.9 21.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ribosomal_L17 PF01196.19 KXG47392.1 - 6.9 7.6 6.6 47 5.0 6.6 2.1 1 1 0 1 1 1 0 Ribosomal protein L17 Peptidase_S76 PF13611.6 KXG47393.1 - 0.025 14.9 0.0 0.082 13.2 0.0 1.9 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 Big_3_3 PF13750.6 KXG47393.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.8 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Tox-PL-2 PF15643.6 KXG47394.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Papain fold toxin 2 F-box PF00646.33 KXG47395.1 - 4.8e-07 29.5 0.2 1.2e-06 28.2 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXG47395.1 - 1.4e-06 28.0 0.2 4.1e-06 26.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like Trp_DMAT PF11991.8 KXG47397.1 - 1.5e-07 31.2 0.1 3e-07 30.2 0.0 1.4 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase p450 PF00067.22 KXG47398.1 - 1.4e-52 179.0 0.0 1.6e-52 178.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_15 PF01793.16 KXG47399.1 - 5.4e-95 318.4 11.3 4.3e-94 315.4 11.3 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PH PF00169.29 KXG47400.1 - 4.8e-29 100.9 0.0 1e-13 51.7 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 KXG47400.1 - 1.9e-10 41.1 0.3 1.6e-05 25.2 0.0 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KXG47400.1 - 2.7e-09 37.4 0.9 0.006 17.0 0.1 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 KXG47400.1 - 0.00053 20.1 0.0 0.69 10.1 0.0 2.3 2 0 0 2 2 2 2 PH domain PH_13 PF16652.5 KXG47400.1 - 0.092 12.6 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Mcp5_PH PF12814.7 KXG47400.1 - 0.15 12.2 0.0 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology EamA PF00892.20 KXG47401.1 - 6.9e-10 39.2 25.1 1.2e-08 35.2 2.7 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KXG47401.1 - 1.1e-05 24.8 8.2 1.6e-05 24.3 8.2 1.1 1 0 0 1 1 1 1 UAA transporter family SLC35F PF06027.12 KXG47401.1 - 0.00014 21.4 6.5 0.00057 19.5 6.5 1.8 1 1 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 KXG47401.1 - 0.00053 19.3 0.8 0.00053 19.3 0.8 1.8 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport Ras PF00071.22 KXG47402.1 - 2.2e-45 154.2 0.1 2.6e-45 153.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXG47402.1 - 2.6e-20 72.9 0.0 4e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG47402.1 - 1.4e-07 31.1 0.0 1.7e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXG47402.1 - 0.00014 21.4 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KXG47402.1 - 0.021 14.6 0.0 0.025 14.4 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 KXG47402.1 - 0.054 12.8 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Glyco_hydro_75 PF07335.11 KXG47402.1 - 0.13 12.6 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 ATG16 PF08614.11 KXG47403.1 - 7.2e-58 196.1 17.8 8.1e-58 196.0 17.8 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) HAUS-augmin3 PF14932.6 KXG47403.1 - 0.00071 19.2 5.1 0.00071 19.2 5.1 1.5 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 CCDC144C PF14915.6 KXG47403.1 - 0.002 17.3 7.8 0.002 17.3 7.8 1.4 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region DUF4201 PF13870.6 KXG47403.1 - 0.0058 16.4 10.1 0.0058 16.4 10.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) UPF0242 PF06785.11 KXG47403.1 - 0.018 15.2 12.2 0.051 13.7 5.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Golgin_A5 PF09787.9 KXG47403.1 - 0.023 14.2 7.1 0.033 13.6 7.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spc7 PF08317.11 KXG47403.1 - 0.19 10.6 12.3 0.42 9.5 1.6 2.2 2 1 1 3 3 3 0 Spc7 kinetochore protein GAS PF13851.6 KXG47403.1 - 0.24 10.7 12.2 0.56 9.5 10.6 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 KXG47403.1 - 0.31 11.7 9.3 1.3 9.7 2.2 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Lebercilin PF15619.6 KXG47403.1 - 0.36 10.5 16.9 0.065 12.9 13.6 1.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease MscS_porin PF12795.7 KXG47403.1 - 0.59 9.6 21.9 0.91 9.0 15.6 2.6 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 KXG47403.1 - 0.71 9.9 5.0 8.7 6.4 3.4 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) Cep57_MT_bd PF06657.13 KXG47403.1 - 0.78 10.2 9.3 8.8 6.9 0.1 3.6 2 1 2 4 4 3 0 Centrosome microtubule-binding domain of Cep57 ABC_tran_CTD PF16326.5 KXG47403.1 - 0.8 10.0 14.9 0.87 9.9 7.0 3.6 2 1 2 4 4 4 0 ABC transporter C-terminal domain DUF2203 PF09969.9 KXG47403.1 - 0.95 10.2 6.5 0.21 12.3 1.6 2.2 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) BRE1 PF08647.11 KXG47403.1 - 1 9.5 12.4 0.44 10.6 7.8 2.4 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Nup54 PF13874.6 KXG47403.1 - 1.7 8.7 12.3 0.54 10.3 3.7 2.5 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 APG6_N PF17675.1 KXG47403.1 - 2.7 8.5 17.8 13 6.4 17.6 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 KXG47403.1 - 2.7 7.2 13.0 0.18 11.1 6.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 KXG47403.1 - 3.4 6.9 16.2 14 4.9 16.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DHR10 PF18595.1 KXG47403.1 - 5.9 7.0 20.1 4.5 7.3 5.1 2.9 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Sec2p PF06428.11 KXG47403.1 - 6.3 6.8 13.8 4.7 7.2 10.4 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Prefoldin_2 PF01920.20 KXG47403.1 - 8.3 6.4 10.1 6.9 6.7 0.5 2.9 2 1 1 3 3 3 0 Prefoldin subunit Cnn_1N PF07989.11 KXG47403.1 - 9.3 6.5 11.7 2.1 8.5 2.9 3.2 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 DOT1 PF08123.13 KXG47404.1 - 6.4e-77 257.7 0.0 8.6e-77 257.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Spb1_C PF07780.12 KXG47405.1 - 1.1e-82 276.8 33.2 1.1e-82 276.8 33.2 4.1 2 1 1 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 KXG47405.1 - 1.1e-56 191.8 0.0 1.8e-56 191.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KXG47405.1 - 4.7e-50 169.6 8.4 4.7e-50 169.6 8.4 4.8 3 1 1 4 4 4 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 KXG47405.1 - 0.015 15.2 0.1 0.08 12.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain TMEM132D_C PF15706.5 KXG47405.1 - 7.5 6.4 6.5 2 8.3 1.0 2.7 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Zn_clus PF00172.18 KXG47407.1 - 6.8e-07 29.3 6.3 1.7e-06 28.0 6.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXG47407.1 - 1.6e-06 27.4 0.1 3.4e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_4 PF12763.7 KXG47408.1 - 8.9e-05 22.4 0.1 0.00017 21.5 0.1 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Fungal_trans PF04082.18 KXG47409.1 - 2e-20 73.0 2.1 3.7e-20 72.1 2.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DNA_ligase_A_M PF01068.21 KXG47410.1 - 2.6e-47 161.1 0.0 9.7e-47 159.3 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXG47410.1 - 1.7e-46 158.7 0.0 1.1e-45 156.0 0.0 2.3 3 0 0 3 3 3 1 DNA ligase N terminus BRCT_2 PF16589.5 KXG47410.1 - 8.6e-20 70.9 0.1 4.7e-13 49.4 0.1 2.7 2 1 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KXG47410.1 - 9.7e-19 67.8 0.7 5.4e-18 65.4 0.0 2.7 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KXG47410.1 - 8.3e-18 65.2 0.0 2.3e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 KXG47410.1 - 7e-08 32.7 0.0 0.0037 17.6 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 KXG47410.1 - 4.6e-07 29.8 0.1 1.1e-06 28.6 0.1 1.7 1 0 0 1 1 1 1 DNA ligase IV LIG3_BRCT PF16759.5 KXG47410.1 - 3.2e-06 27.3 0.7 0.027 14.7 0.1 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KXG47410.1 - 0.00075 19.3 0.0 0.26 11.2 0.1 2.4 2 0 0 2 2 2 2 Regulator of Ty1 transposition protein 107 BRCT domain mRNA_cap_enzyme PF01331.19 KXG47410.1 - 0.093 12.5 0.1 0.64 9.8 0.0 2.5 2 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain Cytochrom_B558a PF05038.13 KXG47411.1 - 5.7 6.5 7.3 12 5.4 0.7 2.3 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Fungal_trans PF04082.18 KXG47412.1 - 3.7e-42 144.2 0.3 6.8e-42 143.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG47412.1 - 4.7e-08 33.0 8.2 9.5e-08 32.1 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.29 KXG47412.1 - 0.0026 17.6 5.8 0.0032 17.3 4.5 1.8 2 0 0 2 2 2 1 PHD-finger DUF3473 PF11959.8 KXG47412.1 - 0.021 14.8 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) COA2 PF17051.5 KXG47413.1 - 0.0088 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 NSP2-B_epitope PF14757.6 KXG47413.1 - 0.048 13.4 0.1 0.063 13.0 0.1 1.1 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein ALG3 PF05208.13 KXG47414.1 - 8.9e-141 469.4 19.0 1e-140 469.2 19.0 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.19 KXG47415.1 - 3.9e-15 55.4 0.3 5.6e-15 54.9 0.3 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF3189 PF11385.8 KXG47415.1 - 0.096 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) Cro PF09048.10 KXG47415.1 - 0.11 12.5 0.4 6.5 6.9 0.1 2.3 1 1 1 2 2 2 0 Cro DDE_1 PF03184.19 KXG47416.1 - 5.9e-13 48.8 0.0 1.3e-12 47.7 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KXG47416.1 - 2.6e-11 43.4 0.5 2.8e-10 40.1 0.0 2.8 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain Pkinase PF00069.25 KXG47417.1 - 8.6e-58 195.8 0.0 1.4e-57 195.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG47417.1 - 2.8e-34 118.6 0.0 4.6e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KXG47417.1 - 1.5e-28 98.7 16.1 1e-15 57.6 4.2 2.7 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KXG47417.1 - 8.1e-21 73.7 28.8 3e-12 46.2 9.5 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KXG47417.1 - 2.1e-14 54.0 1.5 1.9e-13 50.9 1.5 2.7 3 0 0 3 3 3 1 Protein kinase C terminal domain C2 PF00168.30 KXG47417.1 - 2.6e-05 24.4 0.0 5.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 KXG47417.1 - 0.16 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like zf-RING_9 PF13901.6 KXG47417.1 - 3.1 7.7 22.3 1.2 9.1 7.6 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Uds1 PF15456.6 KXG47417.1 - 8.2 6.6 6.4 2.2 8.5 1.1 2.4 2 0 0 2 2 2 0 Up-regulated During Septation MatE PF01554.18 KXG47419.1 - 9.3e-46 155.4 27.6 2.1e-30 105.5 8.2 2.4 2 0 0 2 2 2 2 MatE TFCD_C PF12612.8 KXG47420.1 - 2.5e-35 122.0 0.1 2e-34 119.1 0.1 2.6 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 KXG47420.1 - 0.0003 21.1 6.6 3.1 8.3 0.1 6.1 6 1 1 7 7 7 1 HEAT repeats HEAT PF02985.22 KXG47420.1 - 0.0011 19.0 16.9 0.81 10.1 0.0 8.1 8 0 0 8 8 8 2 HEAT repeat IFRD PF05004.13 KXG47420.1 - 0.0017 17.6 9.1 0.0068 15.6 0.3 3.1 3 0 0 3 3 3 2 Interferon-related developmental regulator (IFRD) Diacid_rec PF05651.13 KXG47420.1 - 0.017 14.8 0.1 0.039 13.6 0.1 1.5 1 0 0 1 1 1 0 Putative sugar diacid recognition Vac14_Fab1_bd PF12755.7 KXG47420.1 - 0.033 14.8 0.1 1.9 9.1 0.0 3.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KXG47420.1 - 1.1 9.9 16.2 4.6 7.8 0.0 7.3 8 0 0 8 8 8 0 HEAT-like repeat Esterase PF00756.20 KXG47421.1 - 0.0013 18.4 0.0 0.0028 17.3 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KXG47421.1 - 0.0054 16.2 0.3 0.015 14.8 0.3 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXG47421.1 - 0.0073 15.8 0.1 0.014 14.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family HTH_36 PF13730.6 KXG47421.1 - 0.086 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain RRM_1 PF00076.22 KXG47422.1 - 1.4e-28 98.5 0.8 1.6e-13 50.2 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXG47422.1 - 8.9e-05 22.3 0.0 0.11 12.4 0.1 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KXG47422.1 - 0.00022 20.8 0.0 0.0014 18.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 KXG47422.1 - 0.036 13.9 0.1 0.097 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) RRM_7 PF16367.5 KXG47422.1 - 0.16 12.1 0.0 12 6.1 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 KXG47422.1 - 0.23 11.7 4.4 4.7 7.4 0.1 3.5 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter ATP-synt_D PF01813.17 KXG47423.1 - 2.5e-63 213.5 1.6 5.8e-57 192.7 0.4 2.2 2 0 0 2 2 2 2 ATP synthase subunit D TniB PF05621.11 KXG47423.1 - 0.038 13.4 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein zf-C4H2 PF10146.9 KXG47423.1 - 1.2 9.5 3.8 0.54 10.5 1.2 1.7 2 0 0 2 2 2 0 Zinc finger-containing protein TPR_14 PF13428.6 KXG47424.1 - 1.6e-16 59.6 20.6 0.63 11.0 0.0 12.6 10 3 4 14 14 13 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXG47424.1 - 4.1e-10 40.0 2.6 0.14 12.7 0.0 6.6 6 1 1 7 7 7 2 Tetratricopeptide repeat Suf PF05843.14 KXG47424.1 - 9.5e-10 38.9 15.4 0.031 14.3 0.1 6.7 5 2 1 6 6 6 4 Suppressor of forked protein (Suf) TPR_8 PF13181.6 KXG47424.1 - 1.4e-08 34.3 8.1 0.026 14.7 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KXG47424.1 - 4.1e-08 33.3 13.2 0.25 11.3 0.1 7.4 6 2 0 6 6 6 2 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 KXG47424.1 - 7.1e-08 32.0 5.3 7.8e-05 22.0 1.0 4.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXG47424.1 - 1.9e-06 27.6 19.0 0.94 9.7 0.0 8.7 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXG47424.1 - 3.7e-06 27.1 5.9 0.67 10.3 0.0 7.4 7 1 0 7 7 7 1 Tetratricopeptide repeat SNAP PF14938.6 KXG47424.1 - 2.4e-05 23.9 1.4 0.012 15.1 0.1 4.3 4 1 0 4 4 4 1 Soluble NSF attachment protein, SNAP MIT PF04212.18 KXG47424.1 - 0.0007 19.6 0.0 0.94 9.6 0.1 4.9 5 0 0 5 5 4 1 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 KXG47424.1 - 0.0036 17.6 7.5 0.058 13.8 0.0 5.6 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXG47424.1 - 0.0086 16.6 0.0 24 6.0 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KXG47424.1 - 0.015 14.4 12.4 0.098 11.8 1.7 5.3 3 2 1 5 5 5 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 KXG47424.1 - 0.023 15.3 11.1 1.2 9.9 0.0 7.7 9 0 0 9 9 8 0 Tetratricopeptide repeat RPN7 PF10602.9 KXG47424.1 - 0.043 13.5 0.1 0.81 9.4 0.1 2.9 3 1 0 3 3 3 0 26S proteasome subunit RPN7 HAT PF02184.16 KXG47424.1 - 0.24 11.4 5.5 3 7.9 0.0 5.4 7 0 0 7 7 6 0 HAT (Half-A-TPR) repeat TPR_10 PF13374.6 KXG47424.1 - 0.39 10.7 7.1 1.3e+02 2.6 0.4 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat Sec7 PF01369.20 KXG47425.1 - 2.9e-63 212.9 0.0 4.6e-63 212.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KXG47425.1 - 1.6e-17 63.8 0.5 1.7e-16 60.5 0.0 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KXG47425.1 - 0.0046 16.7 2.2 0.009 15.7 0.4 2.4 2 1 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF913 PF06025.12 KXG47425.1 - 0.45 9.4 3.0 4.6 6.1 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RhoGEF PF00621.20 KXG47426.1 - 1.2e-21 77.7 0.0 9.2e-21 74.9 0.0 2.2 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.8 KXG47426.1 - 3.5e-06 26.9 0.0 6.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Nod1 PF17114.5 KXG47426.1 - 0.00024 21.3 0.0 0.0012 19.0 0.0 2.2 3 0 0 3 3 3 1 Gef2-related medial cortical node protein Nod1 RhoGAP PF00620.27 KXG47426.1 - 0.024 14.5 0.0 0.86 9.4 0.0 3.2 3 0 0 3 3 3 0 RhoGAP domain FAM184 PF15665.5 KXG47426.1 - 0.05 13.4 2.7 0.15 11.8 2.7 1.7 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B BRI3BP PF14965.6 KXG47426.1 - 0.067 12.7 0.0 6.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Negative regulator of p53/TP53 MPS2 PF17060.5 KXG47426.1 - 5.2 6.2 5.2 5.4 6.2 3.9 1.6 1 1 0 1 1 1 0 Monopolar spindle protein 2 ATP_bind_3 PF01171.20 KXG47427.1 - 3.1e-25 89.0 0.0 1.7e-13 50.7 0.0 2.9 1 1 1 2 2 2 2 PP-loop family TPR_2 PF07719.17 KXG47428.1 - 2.6e-11 42.7 5.5 0.015 15.4 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXG47428.1 - 1.1e-06 28.2 0.0 0.46 10.4 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXG47428.1 - 3.5e-05 24.2 6.1 0.041 14.4 0.2 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXG47428.1 - 0.00016 21.2 0.4 0.16 11.7 0.0 4.4 4 0 0 4 4 4 1 TPR repeat TPR_12 PF13424.6 KXG47428.1 - 0.0041 17.4 10.2 0.015 15.6 1.1 4.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXG47428.1 - 0.0079 16.8 14.8 0.59 10.8 0.4 6.4 6 1 1 7 7 6 3 Tetratricopeptide repeat Ofd1_CTDD PF10637.9 KXG47428.1 - 0.02 14.2 0.1 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term TPR_14 PF13428.6 KXG47428.1 - 0.047 14.5 17.2 5.6 8.1 0.0 7.4 7 1 0 7 7 6 0 Tetratricopeptide repeat PPR_3 PF13812.6 KXG47428.1 - 0.19 11.8 0.1 0.5 10.5 0.1 1.6 1 0 0 1 1 1 0 Pentatricopeptide repeat domain TPR_7 PF13176.6 KXG47428.1 - 0.3 11.2 4.7 21 5.4 0.2 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXG47428.1 - 1.3 9.4 3.3 34 5.0 0.0 4.7 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXG47428.1 - 2.5 8.1 7.0 3.5 7.6 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXG47428.1 - 5.8 7.8 18.6 3.3 8.6 2.1 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF3337 PF11816.8 KXG47429.1 - 4.2e-51 173.2 0.0 1.2e-38 132.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.32 KXG47429.1 - 2.1e-17 63.1 14.2 0.00029 21.6 0.1 7.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXG47429.1 - 0.0026 16.8 0.0 0.1 11.5 0.0 2.2 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KXG47429.1 - 0.0027 18.0 0.2 0.29 11.4 0.1 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXG47429.1 - 0.029 13.0 1.0 0.15 10.7 0.2 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Cupin_5 PF06172.11 KXG47430.1 - 1.4e-49 167.8 0.0 1.7e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Mito_carr PF00153.27 KXG47431.1 - 4.9e-41 138.6 3.2 2.3e-15 56.3 0.1 3.7 3 2 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 KXG47432.1 - 1.7e-44 152.2 0.0 2.8e-41 141.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG47432.1 - 6.3e-19 68.3 0.0 1.2e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXG47432.1 - 0.034 13.1 0.1 0.13 11.1 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 KXG47432.1 - 0.035 14.0 0.4 0.07 13.0 0.4 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L11 PF00298.19 KXG47433.1 - 5e-27 94.2 0.0 7.2e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KXG47433.1 - 5.3e-25 87.0 0.1 8.9e-25 86.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Svf1_C PF17187.4 KXG47434.1 - 7.6e-62 208.0 0.2 1.7e-61 206.9 0.0 1.7 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KXG47434.1 - 1.2e-58 197.8 0.1 1.7e-58 197.3 0.1 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain AAA_6 PF12774.7 KXG47435.1 - 2.5e-124 414.5 0.0 3.9e-123 410.6 0.0 2.8 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KXG47435.1 - 4.5e-123 411.8 6.1 4.5e-123 411.8 6.1 6.0 6 1 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KXG47435.1 - 1.2e-113 380.3 8.1 1.2e-113 380.3 8.1 4.4 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KXG47435.1 - 1.1e-74 250.3 0.6 1.1e-74 250.3 0.6 3.8 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 KXG47435.1 - 2.2e-65 220.6 0.2 8.4e-65 218.7 0.0 2.2 3 0 0 3 3 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KXG47435.1 - 6e-42 143.2 0.0 2.5e-36 124.9 0.0 4.8 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 KXG47435.1 - 3.1e-41 141.5 7.2 5.7e-41 140.7 7.2 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KXG47435.1 - 5.1e-32 110.8 0.3 8.2e-11 42.1 0.0 6.5 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 KXG47435.1 - 1e-29 103.5 0.0 2.5e-29 102.2 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KXG47435.1 - 1.8e-29 102.3 0.1 8.9e-25 87.1 0.0 4.2 5 0 0 5 5 2 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KXG47435.1 - 1.7e-18 66.9 0.0 8.6e-18 64.7 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KXG47435.1 - 2.8e-15 56.9 0.0 9.5e-05 22.8 0.0 5.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXG47435.1 - 2.7e-14 53.6 0.7 0.009 16.3 0.0 6.4 6 0 0 6 6 5 2 AAA domain AAA_18 PF13238.6 KXG47435.1 - 1.4e-11 45.0 0.2 0.047 14.2 0.0 5.2 4 0 0 4 4 4 3 AAA domain AAA_33 PF13671.6 KXG47435.1 - 4.9e-10 39.7 0.9 0.11 12.6 0.0 5.0 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.6 KXG47435.1 - 2.8e-09 37.6 0.0 1.2 9.5 0.0 7.4 6 0 0 6 6 5 1 AAA ATPase domain ABC_tran PF00005.27 KXG47435.1 - 5.5e-07 30.2 1.0 0.12 12.9 0.1 5.5 5 0 0 5 5 3 2 ABC transporter T2SSE PF00437.20 KXG47435.1 - 6.1e-07 28.8 0.0 0.015 14.4 0.0 3.8 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_29 PF13555.6 KXG47435.1 - 9.1e-06 25.3 0.1 0.68 9.7 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_lid_1 PF17857.1 KXG47435.1 - 1.5e-05 25.1 0.2 0.00039 20.6 0.0 3.1 2 0 0 2 2 2 1 AAA+ lid domain Mg_chelatase PF01078.21 KXG47435.1 - 6.5e-05 22.4 0.7 0.58 9.5 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KXG47435.1 - 8.4e-05 22.4 0.2 22 4.7 0.0 4.8 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.18 KXG47435.1 - 0.00019 20.9 0.0 2.1 7.7 0.0 3.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KXG47435.1 - 0.00067 19.6 0.0 8.6 6.2 0.0 3.8 3 0 0 3 3 3 0 RsgA GTPase Rad17 PF03215.15 KXG47435.1 - 0.00069 19.6 1.2 5 7.0 0.0 4.5 5 0 0 5 5 3 0 Rad17 P-loop domain AAA_24 PF13479.6 KXG47435.1 - 0.00072 19.3 0.7 26 4.4 0.0 5.1 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 KXG47435.1 - 0.0022 17.6 0.3 0.45 10.1 0.0 3.7 4 0 0 4 4 2 1 AAA domain RNA_helicase PF00910.22 KXG47435.1 - 0.0028 18.0 0.2 7.9 6.9 0.1 4.6 4 0 0 4 4 4 0 RNA helicase IstB_IS21 PF01695.17 KXG47435.1 - 0.0035 17.1 0.9 0.49 10.1 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein DUF3867 PF12983.7 KXG47435.1 - 0.005 16.9 0.5 0.005 16.9 0.5 3.3 4 0 0 4 4 2 1 Protein of unknown function (DUF3867) BRE1 PF08647.11 KXG47435.1 - 0.0064 16.5 1.3 0.0064 16.5 1.3 4.7 3 1 0 3 3 3 1 BRE1 E3 ubiquitin ligase Zeta_toxin PF06414.12 KXG47435.1 - 0.0076 15.5 0.3 8.1 5.7 0.2 3.9 4 0 0 4 4 4 0 Zeta toxin AAA_19 PF13245.6 KXG47435.1 - 0.0083 16.5 6.9 0.21 11.9 0.0 5.1 5 0 0 5 5 4 1 AAA domain AAA_21 PF13304.6 KXG47435.1 - 0.01 15.7 0.3 8.6 6.1 0.0 3.7 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system RuvB_N PF05496.12 KXG47435.1 - 0.12 12.1 0.0 5.6 6.7 0.0 3.1 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 KXG47435.1 - 0.13 12.0 0.7 11 5.7 0.1 3.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MbeB_N PF04837.12 KXG47435.1 - 0.14 12.4 2.2 1.8 9.0 0.1 3.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region COG2 PF06148.11 KXG47435.1 - 0.23 11.6 0.0 0.23 11.6 0.0 5.9 6 0 0 6 6 3 0 COG (conserved oligomeric Golgi) complex component, COG2 NTPase_1 PF03266.15 KXG47435.1 - 0.39 10.6 3.6 34 4.3 0.0 4.5 5 0 0 5 5 3 0 NTPase Phage_GP20 PF06810.11 KXG47435.1 - 0.59 9.9 18.8 1.3 8.8 0.3 3.6 3 0 0 3 3 2 0 Phage minor structural protein GP20 NACHT PF05729.12 KXG47435.1 - 1.9 8.4 7.3 31 4.4 0.0 4.4 4 0 0 4 4 3 0 NACHT domain DUF4482 PF14818.6 KXG47435.1 - 3.3 8.6 10.5 37 5.2 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) zf-C4H2 PF10146.9 KXG47435.1 - 3.6 7.8 7.3 4.3 7.6 0.0 3.3 2 0 0 2 2 1 0 Zinc finger-containing protein DUF3450 PF11932.8 KXG47435.1 - 3.7 6.8 23.0 0.042 13.1 1.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 KXG47435.1 - 4.5 6.3 11.4 2.2 7.3 5.1 2.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 XhlA PF10779.9 KXG47435.1 - 8.3 6.7 8.4 6.2 7.1 0.3 3.8 2 0 0 2 2 2 0 Haemolysin XhlA Ribonuclease_3 PF00636.26 KXG47436.1 - 3.2e-43 146.6 0.0 1.5e-20 73.7 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXG47436.1 - 3.1e-27 95.3 0.0 4.1e-14 52.9 0.0 3.6 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KXG47436.1 - 7.4e-21 74.1 0.2 3.8e-20 71.8 0.1 2.3 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KXG47436.1 - 1.1e-16 61.2 0.0 2.9e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG47436.1 - 2.6e-14 53.6 0.0 7.6e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXG47436.1 - 7.4e-11 42.1 0.0 2.1e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 KXG47436.1 - 0.0018 19.0 0.1 0.72 10.6 0.0 2.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif SWI2_SNF2 PF18766.1 KXG47436.1 - 0.13 11.9 0.1 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 SWI2/SNF2 ATPase TAP42 PF04177.12 KXG47437.1 - 2e-102 342.6 1.7 2.2e-102 342.5 1.7 1.0 1 0 0 1 1 1 1 TAP42-like family Porphobil_deam PF01379.20 KXG47438.1 - 6e-72 241.4 0.0 8.1e-72 241.0 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KXG47438.1 - 3.7e-17 62.4 0.3 1e-16 61.1 0.2 1.8 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain Fibrinogen_aC PF12160.8 KXG47438.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha C domain Lon_C PF05362.13 KXG47439.1 - 6e-71 238.2 0.2 2e-70 236.5 0.1 1.9 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KXG47439.1 - 8.2e-30 104.2 0.0 1.4e-29 103.5 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KXG47439.1 - 5.7e-23 81.8 0.0 2.6e-22 79.6 0.0 2.2 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXG47439.1 - 1.5e-07 31.5 0.0 5e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KXG47439.1 - 1.5e-07 31.3 0.0 1.6e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KXG47439.1 - 2.7e-06 27.9 0.6 1.1e-05 25.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 KXG47439.1 - 1.9e-05 24.5 0.0 8.8e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KXG47439.1 - 0.0001 21.6 0.0 0.00019 20.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KXG47439.1 - 0.00015 22.1 0.3 0.0041 17.4 0.0 3.3 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KXG47439.1 - 0.00049 19.9 0.1 0.0014 18.4 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXG47439.1 - 0.00062 19.9 0.0 0.0022 18.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KXG47439.1 - 0.00088 19.0 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KXG47439.1 - 0.0016 18.6 0.0 0.0043 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KXG47439.1 - 0.017 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KXG47439.1 - 0.022 14.8 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXG47439.1 - 0.027 15.0 0.0 0.081 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXG47439.1 - 0.03 14.7 0.0 0.28 11.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.16 KXG47439.1 - 0.034 13.6 0.0 0.085 12.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 KXG47439.1 - 0.046 13.6 0.1 1.7 8.5 0.0 2.8 2 1 1 3 3 2 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KXG47439.1 - 0.05 13.4 0.3 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXG47439.1 - 0.053 12.9 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KXG47439.1 - 0.053 13.1 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXG47439.1 - 0.056 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TniB PF05621.11 KXG47439.1 - 0.083 12.3 0.0 0.27 10.6 0.0 1.8 1 0 0 1 1 1 0 Bacterial TniB protein AAA_PrkA PF08298.11 KXG47439.1 - 0.084 11.8 0.0 0.48 9.3 0.0 1.9 2 0 0 2 2 2 0 PrkA AAA domain AAA_30 PF13604.6 KXG47439.1 - 0.095 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXG47439.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KXG47439.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KXG47439.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 KXG47439.1 - 0.25 11.8 6.4 0.55 10.7 0.0 3.2 2 1 0 2 2 1 0 AAA domain SpoIIIAH PF12685.7 KXG47439.1 - 0.45 10.3 1.3 0.9 9.3 1.3 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein CCDC-167 PF15188.6 KXG47439.1 - 1.5 9.2 5.4 1.2 9.5 1.9 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Ribosomal_L23 PF00276.20 KXG47440.1 - 1.4e-09 38.2 0.0 2.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 RIO1 PF01163.22 KXG47441.1 - 1.2e-40 139.1 0.7 4.6e-29 101.4 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 KXG47441.1 - 2.1e-30 104.7 0.0 1e-29 102.6 0.0 2.0 2 0 0 2 2 2 1 Rio2, N-terminal Kdo PF06293.14 KXG47441.1 - 4.2e-07 29.5 0.0 1.6e-05 24.4 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXG47441.1 - 2.9e-05 24.1 0.0 0.13 12.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RPN1_RPN2_N PF17781.1 KXG47442.1 - 8.4e-118 393.3 0.7 1.5e-117 392.5 0.7 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KXG47442.1 - 3.2e-30 103.9 0.0 6e-30 103.1 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KXG47442.1 - 7.6e-18 64.0 16.0 2.8e-05 24.3 0.2 7.7 7 0 0 7 7 7 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KXG47442.1 - 1.9e-05 24.9 0.4 0.53 10.7 0.0 4.2 3 2 1 4 4 4 3 HEAT repeats Tom22 PF04281.13 KXG47442.1 - 2 8.2 6.4 4.8 7.0 6.4 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Mlh1_C PF16413.5 KXG47444.1 - 1.4e-97 326.3 0.0 2.1e-97 325.7 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KXG47444.1 - 4.1e-33 113.6 0.2 6.6e-33 112.9 0.2 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KXG47444.1 - 1.1e-13 51.1 0.0 2.9e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXG47444.1 - 5.3e-08 33.4 0.0 1.3e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MFS_1 PF07690.16 KXG47445.1 - 1.7e-42 145.7 43.2 1.7e-42 145.7 43.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG47445.1 - 2.1e-15 56.2 26.9 2.8e-15 55.8 26.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXG47445.1 - 3.6e-13 49.2 29.6 5.7e-13 48.5 14.4 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter DUF2585 PF10755.9 KXG47447.1 - 0.07 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2585) AMP-binding PF00501.28 KXG47448.1 - 5.1e-53 180.2 0.0 6.9e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KXG47448.1 - 6.4e-29 101.7 0.1 1.1e-27 97.7 0.1 2.5 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 KXG47448.1 - 8e-08 32.5 0.3 2e-07 31.3 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 KXG47448.1 - 5.2e-05 24.0 0.1 0.00011 22.9 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG47448.1 - 0.0076 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG47448.1 - 0.04 13.2 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF4383 PF14325.6 KXG47449.1 - 7 7.0 12.8 7.5 6.9 2.6 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4383) Methyltransf_2 PF00891.18 KXG47450.1 - 4.9e-30 104.4 0.0 8.6e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KXG47450.1 - 0.00042 21.0 0.0 0.0014 19.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG47450.1 - 0.0013 19.4 0.0 0.003 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG47450.1 - 0.0061 17.2 0.0 0.014 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG47450.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 KXG47450.1 - 0.026 14.0 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.14 KXG47450.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Lyase_aromatic PF00221.19 KXG47451.1 - 6e-151 503.2 5.2 8.1e-151 502.8 5.2 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase CLZ PF16526.5 KXG47451.1 - 0.1 13.0 0.1 0.51 10.7 0.0 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HNH_2 PF13391.6 KXG47453.1 - 7.1e-14 51.7 0.0 1.6e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Metallophos PF00149.28 KXG47454.1 - 1.9e-06 28.5 0.1 4.4e-06 27.3 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXG47454.1 - 0.0013 19.0 0.0 0.12 12.6 0.0 2.4 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain CEBP1_N PF16368.5 KXG47454.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein 1 N-terminus DSPc PF00782.20 KXG47455.1 - 9.3e-28 96.7 0.0 3.4e-20 72.2 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXG47455.1 - 9.6e-05 22.1 0.0 0.0024 17.5 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase ANAPC4_WD40 PF12894.7 KXG47456.1 - 3.8e-05 23.9 0.0 0.08 13.3 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 KXG47456.1 - 0.0011 18.7 0.1 0.029 14.0 0.1 2.4 2 0 0 2 2 2 1 CNH domain Coatomer_WDAD PF04053.14 KXG47456.1 - 0.0045 16.1 0.0 0.017 14.2 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region Hira PF07569.11 KXG47456.1 - 0.04 13.6 0.2 0.55 9.9 0.0 2.6 3 0 0 3 3 3 0 TUP1-like enhancer of split WD40 PF00400.32 KXG47456.1 - 0.044 14.7 0.2 7.4 7.6 0.0 3.7 4 1 1 5 5 5 0 WD domain, G-beta repeat EF-hand_6 PF13405.6 KXG47457.1 - 1e-09 37.5 0.1 0.0019 18.0 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KXG47457.1 - 3.8e-05 24.1 0.9 0.00088 19.7 0.0 2.4 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KXG47457.1 - 0.0042 16.5 0.0 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 EF hand Ric8 PF10165.9 KXG47457.1 - 0.13 11.3 0.0 1.4 7.8 0.0 2.0 2 0 0 2 2 2 0 Guanine nucleotide exchange factor synembryn Skp1 PF01466.19 KXG47457.1 - 0.16 12.1 1.9 12 6.1 0.0 2.6 2 1 0 2 2 2 0 Skp1 family, dimerisation domain SAP18 PF06487.12 KXG47458.1 - 0.091 12.9 0.1 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) DUF5082 PF16888.5 KXG47458.1 - 0.099 12.9 7.1 0.19 12.0 2.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Com_YlbF PF06133.11 KXG47458.1 - 0.32 11.6 3.2 0.86 10.2 3.2 1.7 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA APG6_N PF17675.1 KXG47458.1 - 1.1 9.8 12.4 2.7 8.5 3.9 3.2 3 1 0 3 3 3 0 Apg6 coiled-coil region OB_NTP_bind PF07717.16 KXG47459.1 - 1.4e-24 86.2 0.0 1.1e-23 83.4 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KXG47459.1 - 2.1e-19 69.8 0.0 5.6e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXG47459.1 - 1.4e-10 41.5 0.0 4e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXG47459.1 - 5.7e-07 29.5 0.1 1e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXG47459.1 - 0.00088 19.6 0.0 0.0027 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KXG47459.1 - 0.00095 18.8 0.3 0.0031 17.2 0.3 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KXG47459.1 - 0.021 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KXG47459.1 - 0.029 14.9 0.0 0.053 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KXG47459.1 - 0.03 13.4 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KXG47459.1 - 0.053 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KXG47459.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Flavi_DEAD PF07652.14 KXG47459.1 - 0.15 12.0 0.1 0.39 10.7 0.1 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain PRMT5_TIM PF17285.2 KXG47460.1 - 4.8e-73 245.5 0.0 6.9e-73 245.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 KXG47460.1 - 2.9e-66 222.6 0.0 5.8e-66 221.6 0.0 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KXG47460.1 - 1.5e-55 187.8 0.1 2.8e-55 186.9 0.1 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Lipase_3 PF01764.25 KXG47460.1 - 2.2e-34 118.4 0.0 4e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KXG47460.1 - 7.3e-12 45.2 0.2 2.1e-11 43.7 0.2 1.8 1 0 0 1 1 1 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 KXG47460.1 - 3.8e-06 26.4 0.0 6.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXG47460.1 - 0.00016 22.3 1.9 0.00064 20.4 0.1 2.7 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KXG47460.1 - 0.0031 17.7 0.0 0.0071 16.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_8 PF06259.12 KXG47460.1 - 0.0052 16.4 0.1 0.014 15.0 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase Cutinase PF01083.22 KXG47460.1 - 0.053 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Cutinase Ser_hydrolase PF06821.13 KXG47460.1 - 0.088 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase DUF2974 PF11187.8 KXG47460.1 - 0.22 11.1 0.2 2 7.9 0.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S10 PF00450.22 KXG47461.1 - 2.3e-90 304.0 1.2 2.8e-90 303.7 1.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Inhibitor_I78 PF11720.8 KXG47462.1 - 0.16 12.1 0.0 21 5.2 0.0 2.4 2 0 0 2 2 2 0 Peptidase inhibitor I78 family Cadherin_C_2 PF16492.5 KXG47464.1 - 0.26 12.0 2.3 1.2 10.0 2.3 2.3 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal AA_permease_2 PF13520.6 KXG47465.1 - 1.2e-47 162.7 58.4 1.5e-47 162.4 58.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG47465.1 - 3.9e-24 85.1 49.3 5.7e-24 84.5 49.3 1.2 1 0 0 1 1 1 1 Amino acid permease Phage_r1t_holin PF16945.5 KXG47465.1 - 0.089 13.0 2.4 2.2 8.5 0.6 3.1 2 0 0 2 2 2 0 Putative lactococcus lactis phage r1t holin zf-C2H2 PF00096.26 KXG47466.1 - 9.9e-06 25.7 11.5 0.0034 17.7 2.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXG47466.1 - 0.031 15.1 9.0 0.22 12.5 0.9 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger CHORD PF04968.12 KXG47466.1 - 0.31 11.8 4.9 1.6 9.5 0.4 2.4 1 1 1 2 2 2 0 CHORD FOXP-CC PF16159.5 KXG47466.1 - 0.5 11.0 3.2 9.8 6.9 0.3 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-CGNR PF11706.8 KXG47466.1 - 2.3 8.2 5.2 0.57 10.1 1.7 1.8 2 0 0 2 2 2 0 CGNR zinc finger SOG2 PF10428.9 KXG47466.1 - 5.4 6.1 14.7 7.1 5.7 14.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ABC2_membrane PF01061.24 KXG47467.1 - 2e-85 285.5 44.6 2.6e-46 157.7 18.4 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KXG47467.1 - 1.8e-39 135.4 0.0 9.2e-20 71.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXG47467.1 - 2.8e-28 97.6 5.9 6.1e-24 83.8 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KXG47467.1 - 1.5e-13 50.6 25.2 2.6e-08 33.4 10.0 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 KXG47467.1 - 3e-10 40.6 0.2 8.4e-10 39.1 0.2 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KXG47467.1 - 9.3e-05 22.9 0.1 0.038 14.4 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KXG47467.1 - 0.00011 21.9 0.1 0.01 15.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXG47467.1 - 0.00018 21.5 0.3 0.0068 16.3 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KXG47467.1 - 0.00089 19.5 0.0 0.71 10.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXG47467.1 - 0.001 19.3 0.0 1.5 9.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXG47467.1 - 0.0016 18.2 0.6 0.071 12.9 0.2 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KXG47467.1 - 0.0044 17.6 0.0 1.4 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXG47467.1 - 0.0084 16.4 1.2 1.2 9.4 0.9 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXG47467.1 - 0.034 14.0 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 KXG47467.1 - 0.049 14.1 0.0 3.3 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KXG47467.1 - 0.055 13.1 1.4 3 7.4 0.6 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KXG47467.1 - 0.073 12.8 0.1 4.6 6.9 0.2 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KXG47467.1 - 0.091 12.5 1.0 8.7 6.1 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.19 KXG47467.1 - 0.11 11.9 0.0 0.81 9.1 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MRVI1 PF05781.12 KXG47467.1 - 0.16 10.7 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 MRVI1 protein RuvB_N PF05496.12 KXG47467.1 - 0.17 11.6 0.2 5.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Sugar_tr PF00083.24 KXG47470.1 - 1.4e-77 261.5 15.3 1.6e-77 261.3 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG47470.1 - 2.8e-12 46.2 29.2 2.8e-12 46.2 29.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily PQ-loop PF04193.14 KXG47470.1 - 4.8 7.0 8.4 13 5.6 0.7 4.4 4 0 0 4 4 4 0 PQ loop repeat MFS_1 PF07690.16 KXG47471.1 - 3.4e-29 101.9 23.4 3.4e-29 101.9 23.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG47471.1 - 0.00078 18.4 26.5 0.0033 16.4 12.6 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter TauD PF02668.16 KXG47472.1 - 2e-46 159.0 0.4 2.4e-46 158.7 0.4 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3433 PF11915.8 KXG47473.1 - 2.4e-37 127.3 12.1 1.3e-21 76.8 1.1 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) COX2_TM PF02790.15 KXG47473.1 - 0.011 15.9 5.7 0.28 11.4 1.4 2.9 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain F-box-like PF12937.7 KXG47474.1 - 4.7e-06 26.4 0.5 1.2e-05 25.1 0.5 1.8 1 0 0 1 1 1 1 F-box-like GDPD PF03009.17 KXG47475.1 - 1.6e-70 237.9 0.0 3.1e-70 236.8 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KXG47475.1 - 2.7e-28 98.4 0.0 5.4e-10 39.7 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG47475.1 - 2e-24 85.6 1.8 1.1e-08 35.4 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.19 KXG47475.1 - 4.9e-23 82.7 12.2 2.2e-10 41.0 0.1 4.1 3 1 1 4 4 4 3 SPX domain Ank_3 PF13606.6 KXG47475.1 - 2.5e-18 64.2 0.1 0.025 15.1 0.0 7.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KXG47475.1 - 5.2e-18 64.9 0.6 8.6e-08 32.3 0.0 5.3 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KXG47475.1 - 1e-17 63.7 0.0 0.001 19.4 0.0 6.0 5 0 0 5 5 5 5 Ankyrin repeat UNC45-central PF11701.8 KXG47476.1 - 3.6e-43 147.2 1.4 1.5e-42 145.2 0.2 2.7 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central TPR_15 PF13429.6 KXG47476.1 - 0.072 12.3 0.2 0.13 11.4 0.2 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Arm PF00514.23 KXG47476.1 - 0.15 12.1 19.2 8.2 6.6 0.0 7.4 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat Tfb4 PF03850.14 KXG47477.1 - 4.7e-121 403.5 0.0 5.5e-121 403.3 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Actin PF00022.19 KXG47478.1 - 1.6e-88 297.1 0.0 5.9e-86 288.6 0.0 2.1 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXG47478.1 - 0.056 12.3 0.0 1.6 7.5 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein tRNA_U5-meth_tr PF05958.11 KXG47479.1 - 1.1e-12 47.6 0.0 7.3e-11 41.7 0.0 2.5 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 KXG47479.1 - 3.5e-06 26.9 0.2 1.4e-05 25.0 0.2 2.0 1 0 0 1 1 1 1 TRAM domain Methyltransf_25 PF13649.6 KXG47479.1 - 0.0022 18.7 0.0 0.0072 17.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG47479.1 - 0.003 17.4 0.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 KXG47479.1 - 0.035 13.7 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KXG47479.1 - 0.045 13.1 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ribosomal_S5_C PF03719.15 KXG47480.1 - 1.2e-20 72.7 0.0 2.3e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KXG47480.1 - 2.1e-15 56.4 0.0 2.1e-15 56.4 0.0 2.2 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Alba PF01918.21 KXG47480.1 - 0.028 14.2 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Alba DASH_Dad3 PF08656.10 KXG47481.1 - 1.3e-26 92.4 0.4 2.2e-26 91.8 0.4 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad3 FA_desaturase PF00487.24 KXG47482.1 - 7.5e-27 94.8 29.7 1.1e-26 94.2 29.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXG47482.1 - 1.4e-10 41.2 0.0 2.8e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.25 KXG47483.1 - 1.8e-74 250.4 0.0 2.5e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG47483.1 - 1.7e-30 106.2 0.0 9.6e-22 77.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXG47483.1 - 1.6e-08 34.3 0.0 0.028 13.7 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KXG47483.1 - 0.002 17.0 0.0 0.0036 16.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXG47483.1 - 0.016 15.2 0.0 1.6 8.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KXG47483.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXG47483.1 - 0.13 11.2 0.0 0.32 9.9 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain His_Phos_2 PF00328.22 KXG47485.1 - 6.1e-06 25.8 0.0 5e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TRF PF08558.10 KXG47486.1 - 7.4e-89 297.5 0.4 1.2e-88 296.8 0.4 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KXG47486.1 - 0.00059 20.0 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain TFIID_30kDa PF03540.13 KXG47487.1 - 4.4e-22 77.8 0.1 6.4e-22 77.2 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 KXG47487.1 - 0.51 10.9 3.7 0.52 10.9 1.1 2.3 2 1 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_S19 PF00203.21 KXG47488.1 - 9.9e-25 86.2 0.0 1.2e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 IPK PF03770.16 KXG47489.1 - 1.4e-60 204.5 0.0 2.3e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase MYCBPAP PF14646.6 KXG47489.1 - 0.068 12.1 1.3 0.1 11.5 1.3 1.2 1 0 0 1 1 1 0 MYCBP-associated protein family DNA_pol_phi PF04931.13 KXG47489.1 - 9 4.3 12.0 13 3.7 12.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Arb1 PF09692.10 KXG47490.1 - 1.7e-115 386.5 0.0 2.6e-115 385.8 0.0 1.3 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 ADH_zinc_N PF00107.26 KXG47491.1 - 1.3e-27 96.3 0.0 2e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG47491.1 - 2.2e-21 77.3 0.0 3.8e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG47491.1 - 3.3e-10 39.8 0.0 3.2e-08 33.4 0.0 2.7 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KXG47491.1 - 0.043 13.7 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase FAD_binding_3 PF01494.19 KXG47494.1 - 5.5e-49 167.3 0.0 1.7e-48 165.7 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXG47494.1 - 4.1e-26 92.0 0.0 1.2e-25 90.4 0.0 1.8 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.10 KXG47494.1 - 0.041 12.9 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase KinB_sensor PF16767.5 KXG47494.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB CLP1_N PF16573.5 KXG47495.1 - 1.7e-33 114.7 0.0 3.3e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 KXG47495.1 - 5.4e-30 104.6 0.0 3e-29 102.2 0.0 2.1 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KXG47495.1 - 1.5e-23 83.4 0.0 3.6e-23 82.2 0.0 1.7 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 KXG47495.1 - 0.00017 21.5 0.0 0.00071 19.4 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KXG47495.1 - 0.0011 19.1 0.1 0.006 16.7 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KXG47495.1 - 0.015 15.1 0.1 0.022 14.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KXG47495.1 - 0.026 14.1 0.1 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 KXG47495.1 - 0.074 13.3 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 KXG47495.1 - 0.21 10.4 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain KilA-N PF04383.13 KXG47496.1 - 0.001 18.9 4.7 0.0094 15.8 0.0 3.2 2 1 1 3 3 3 1 KilA-N domain FmiP_Thoc5 PF09766.9 KXG47496.1 - 1.6 8.0 14.0 2.6 7.2 4.2 2.2 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 DUF4337 PF14235.6 KXG47496.1 - 3.4 7.8 19.6 1.3 9.2 5.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Rho_GDI PF02115.17 KXG47497.1 - 7.6e-64 215.1 0.8 8.4e-64 214.9 0.8 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.28 KXG47498.1 - 8.5e-36 124.4 0.2 1.2e-35 123.9 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXG47498.1 - 0.076 13.5 0.3 0.22 12.0 0.3 1.8 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KXG47498.1 - 0.1 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Amidohydro_1 PF01979.20 KXG47499.1 - 2.5e-46 158.6 0.0 3.1e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXG47499.1 - 5.1e-23 82.3 0.1 4.9e-16 59.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Adaptin_N PF01602.20 KXG47500.1 - 8.7e-98 328.1 0.0 2e-97 327.0 0.0 1.5 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXG47500.1 - 3.6e-15 56.4 0.1 1.7e-13 50.9 0.0 3.3 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXG47500.1 - 1.5e-09 38.1 0.1 0.0021 18.4 0.0 4.0 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KXG47500.1 - 2.8e-07 30.2 0.9 0.086 13.1 0.0 5.2 6 0 0 6 6 6 2 HEAT repeat Cohesin_HEAT PF12765.7 KXG47500.1 - 0.00028 21.1 0.2 0.018 15.3 0.0 3.1 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 KXG47500.1 - 0.00068 20.1 1.5 3.9 8.1 0.0 4.8 5 0 0 5 5 5 1 HEAT-like repeat TFIIA PF03153.13 KXG47500.1 - 0.0079 16.2 8.5 0.014 15.4 8.5 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SpoIIIAH PF12685.7 KXG47500.1 - 0.058 13.2 10.3 1.1 9.1 8.3 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein BUD22 PF09073.10 KXG47500.1 - 0.41 9.9 18.4 1.7 7.9 12.7 2.5 3 0 0 3 3 3 0 BUD22 SDA1 PF05285.12 KXG47500.1 - 2 7.8 26.4 1.7 8.0 17.6 2.3 2 0 0 2 2 2 0 SDA1 DUF2052 PF09747.9 KXG47500.1 - 5.2 7.1 23.0 4.5 7.4 14.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Nuf2 PF03800.14 KXG47502.1 - 6e-44 149.5 0.2 1.7e-43 148.1 0.2 1.8 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KXG47502.1 - 4.9e-34 116.9 19.1 4.9e-34 116.9 19.1 3.8 3 1 0 3 3 3 1 Designed helical repeat protein 10 domain Bacillus_HBL PF05791.11 KXG47502.1 - 0.013 15.3 5.4 0.013 15.3 5.4 3.2 1 1 3 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) IFT46_B_C PF12317.8 KXG47502.1 - 8 6.1 10.8 1.3 8.7 5.7 2.3 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal IF-2B PF01008.17 KXG47503.1 - 4.7e-49 167.1 0.0 5.9e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 KXG47503.1 - 0.17 11.8 0.0 7.5 6.5 0.1 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain Thioredoxin PF00085.20 KXG47506.1 - 2.1e-28 98.3 0.1 2.4e-28 98.1 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXG47506.1 - 6.6e-08 33.0 0.1 1.3e-07 32.0 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXG47506.1 - 2.4e-06 27.8 0.0 3.3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KXG47506.1 - 1.8e-05 24.6 0.1 2.2e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KXG47506.1 - 0.00027 21.1 0.1 0.0004 20.5 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KXG47506.1 - 0.00037 20.3 0.0 0.00045 20.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KXG47506.1 - 0.0063 16.2 0.3 0.0079 15.9 0.3 1.3 1 1 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 KXG47506.1 - 0.008 15.6 0.0 0.0089 15.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_5 PF13743.6 KXG47506.1 - 0.016 14.9 0.1 0.12 12.0 0.0 1.9 1 1 1 2 2 2 0 Thioredoxin DSBA PF01323.20 KXG47506.1 - 0.024 14.4 0.1 3.2 7.5 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Glutaredoxin PF00462.24 KXG47506.1 - 0.073 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Peripla_BP_4 PF13407.6 KXG47507.1 - 0.016 14.8 0.1 0.043 13.4 0.1 1.7 1 0 0 1 1 1 0 Periplasmic binding protein domain CENP-P PF13096.6 KXG47508.1 - 0.05 13.3 0.1 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Acetyltransf_4 PF13420.7 KXG47509.1 - 0.00035 20.7 0.0 0.00053 20.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXG47509.1 - 0.011 16.5 0.1 0.017 15.8 0.0 1.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MHYT PF03707.16 KXG47510.1 - 9.9e-19 67.3 21.1 3.7e-09 36.6 1.5 4.1 4 1 0 4 4 4 3 Bacterial signalling protein N terminal repeat Virul_fac_BrkB PF03631.15 KXG47510.1 - 1.8 8.1 9.8 3.5 7.2 6.0 2.2 2 0 0 2 2 2 0 Virulence factor BrkB DUF775 PF05603.12 KXG47511.1 - 1.8e-63 213.7 0.0 2e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF4743 PF15916.5 KXG47512.1 - 7.5e-14 51.7 0.0 1.1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KXG47512.1 - 5.6e-11 42.6 0.0 9.4e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.15 KXG47513.1 - 1.4e-47 161.3 0.0 1.6e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KXG47513.1 - 8.6e-05 22.6 0.0 0.016 15.3 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G PAXNEB PF05625.11 KXG47514.1 - 5.1e-117 391.1 0.0 5.8e-117 390.9 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.17 KXG47515.1 - 2.1e-14 53.3 0.0 4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain MTES_1575 PF18741.1 KXG47515.1 - 0.017 15.3 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 REase_MTES_1575 Ndc1_Nup PF09531.10 KXG47515.1 - 8.1 5.0 6.3 11 4.6 6.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UPF0086 PF01868.16 KXG47516.1 - 1.2e-31 108.4 0.4 2e-31 107.8 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 2OG-FeII_Oxy PF03171.20 KXG47517.1 - 2.1e-14 53.8 0.0 3.7e-13 49.8 0.0 2.4 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXG47517.1 - 3.6e-11 43.9 0.0 5.7e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DZR PF12773.7 KXG47518.1 - 0.067 13.2 25.9 0.58 10.2 8.9 3.6 2 2 1 3 3 3 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KXG47518.1 - 1.1 10.0 20.2 1.9 9.3 1.6 3.7 2 1 1 3 3 3 0 zinc-ribbon family Zn_ribbon_17 PF17120.5 KXG47518.1 - 1.1 8.9 31.3 0.7 9.6 4.1 3.2 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type HypA PF01155.19 KXG47518.1 - 5.6 7.0 23.5 8.7 6.4 1.3 3.3 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cofilin_ADF PF00241.20 KXG47519.1 - 7.8e-19 67.7 0.1 9.3e-19 67.4 0.1 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.24 KXG47520.1 - 2.5e-36 124.5 0.0 4.2e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.22 KXG47521.1 - 1.1e-54 184.5 1.4 3.3e-54 182.9 1.4 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXG47521.1 - 5.2e-18 65.4 0.0 9.4e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KXG47521.1 - 2.8e-07 30.3 0.0 4.9e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KXG47521.1 - 1.5e-06 27.8 0.0 6.6e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXG47521.1 - 5.8e-05 23.1 0.2 0.23 11.4 0.1 2.4 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KXG47521.1 - 0.0015 18.5 0.0 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KXG47521.1 - 0.0032 17.5 0.0 0.0058 16.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXG47521.1 - 0.0077 15.8 0.0 0.04 13.4 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Septin PF00735.18 KXG47521.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Septin ATP_bind_1 PF03029.17 KXG47521.1 - 0.045 13.5 0.3 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CbiA PF01656.23 KXG47521.1 - 0.065 13.3 0.1 0.18 11.8 0.1 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.17 KXG47521.1 - 0.16 11.7 0.0 2.5 7.8 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein ParA PF10609.9 KXG47521.1 - 0.22 10.9 0.3 1 8.7 0.1 1.9 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase SnoaL_4 PF13577.6 KXG47523.1 - 2.2e-09 37.5 0.2 3.3e-09 36.9 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 KXG47523.1 - 0.0014 19.3 0.5 0.0024 18.5 0.5 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXG47523.1 - 0.0049 17.2 0.2 0.015 15.7 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 KXG47523.1 - 0.029 14.6 0.5 0.054 13.8 0.5 1.4 1 0 0 1 1 1 0 SnoaL-like domain MIT PF04212.18 KXG47524.1 - 0.0069 16.4 0.6 0.012 15.6 0.6 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 KXG47524.1 - 0.017 15.3 0.1 0.044 14.0 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXG47524.1 - 0.021 14.5 0.1 0.046 13.4 0.1 1.5 1 0 0 1 1 1 0 TPR repeat TPR_7 PF13176.6 KXG47524.1 - 0.023 14.7 0.0 0.074 13.1 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXG47524.1 - 0.048 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXG47524.1 - 0.065 14.1 0.0 0.84 10.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXG47524.1 - 0.067 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXG47524.1 - 0.13 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5113 PF17140.4 KXG47524.1 - 0.16 11.8 0.1 0.25 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) Sporozoite_P67 PF05642.11 KXG47525.1 - 0.55 8.2 13.9 0.61 8.1 13.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAP1 PF07218.11 KXG47525.1 - 5.9 5.1 10.0 6.7 4.9 10.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DNA_pol_viral_N PF00242.17 KXG47525.1 - 8.3 5.8 9.2 12 5.3 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain adh_short PF00106.25 KXG47526.1 - 8.5e-55 185.2 0.2 1.1e-54 184.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG47526.1 - 1.2e-35 123.2 0.3 1.5e-35 122.8 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG47526.1 - 4.6e-13 49.5 0.0 7.5e-13 48.8 0.0 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXG47526.1 - 0.00065 18.9 0.7 0.0015 17.7 0.7 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KXG47526.1 - 0.00075 19.8 0.1 0.0014 18.9 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 KXG47526.1 - 0.064 12.6 0.2 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 ThiF family THF_DHG_CYH_C PF02882.19 KXG47526.1 - 0.16 11.3 1.6 1 8.6 0.1 2.7 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RsgA_GTPase PF03193.16 KXG47526.1 - 0.19 11.6 1.7 0.9 9.4 0.5 2.1 1 1 1 2 2 2 0 RsgA GTPase MFS_1 PF07690.16 KXG47528.1 - 9.5e-31 107.0 32.4 1.3e-30 106.5 31.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXG47528.1 - 0.00011 21.7 9.4 0.00046 19.6 5.9 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB YcxB PF14317.6 KXG47528.1 - 0.028 14.1 0.0 0.099 12.4 0.0 1.9 2 0 0 2 2 2 0 YcxB-like protein DUF373 PF04123.13 KXG47528.1 - 0.54 9.6 0.0 0.54 9.6 0.0 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF373) YceD PF02620.17 KXG47529.1 - 1.4 9.1 6.6 0.43 10.7 0.6 2.2 1 1 1 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD EHN PF06441.12 KXG47530.1 - 5.4e-14 52.5 0.0 8.8e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXG47530.1 - 3.5e-10 40.0 0.0 6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG47530.1 - 7.4e-06 26.7 0.5 2.2e-05 25.2 0.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Phytase PF02333.15 KXG47532.1 - 2.6e-68 230.7 3.9 6.8e-65 219.5 0.6 2.2 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.13 KXG47532.1 - 0.00015 22.1 13.1 0.00061 20.1 13.1 2.1 1 1 0 1 1 1 1 EGF-like domain Lactonase PF10282.9 KXG47532.1 - 0.041 13.1 0.1 15 4.7 0.0 3.0 3 1 0 3 3 3 0 Lactonase, 7-bladed beta-propeller OPT PF03169.15 KXG47533.1 - 1.3e-175 585.6 44.6 1.4e-175 585.4 44.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FAD_binding_3 PF01494.19 KXG47534.1 - 1.3e-12 47.7 0.1 5e-11 42.5 0.1 2.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXG47534.1 - 0.00047 20.3 0.1 0.0012 19.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG47534.1 - 0.015 14.5 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG47534.1 - 0.018 14.6 0.1 0.048 13.2 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Cep3 PF16846.5 KXG47534.1 - 0.032 12.7 0.1 0.049 12.1 0.1 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B MFS_1 PF07690.16 KXG47536.1 - 7.3e-34 117.2 34.3 4.2e-32 111.4 36.3 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2243 PF10002.9 KXG47536.1 - 0.0068 16.5 1.6 0.028 14.5 1.6 2.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2243) ESSS PF10183.9 KXG47536.1 - 0.097 12.9 0.2 0.53 10.5 0.1 2.3 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Holin_BhlA PF10960.8 KXG47536.1 - 0.13 12.3 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 BhlA holin family MFS_1 PF07690.16 KXG47538.1 - 2.2e-30 105.8 22.6 3.3e-29 101.9 23.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_31 PF01055.26 KXG47539.1 - 1.1e-88 298.3 0.9 2.2e-88 297.4 0.6 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXG47539.1 - 6.7e-13 48.8 0.0 2.3e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KXG47539.1 - 0.0029 17.8 0.0 0.0078 16.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Tri3 PF07428.11 KXG47540.1 - 1.1e-07 31.2 0.1 0.00011 21.2 0.0 2.5 2 1 1 3 3 3 2 15-O-acetyltransferase Tri3 PapA_C PF16911.5 KXG47540.1 - 0.029 14.5 0.0 0.099 12.7 0.0 1.9 1 1 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus DUF3459 PF11941.8 KXG47540.1 - 0.06 13.7 0.2 8.7 6.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3459) BBS2_C PF14782.6 KXG47540.1 - 0.094 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal FAD_binding_4 PF01565.23 KXG47542.1 - 7.1e-20 71.2 3.4 1.6e-19 70.0 3.4 1.6 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.22 KXG47543.1 - 4.9e-47 160.7 0.0 6e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nitroreductase PF00881.24 KXG47545.1 - 1.6e-13 51.1 0.0 1.9e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family MFS_1 PF07690.16 KXG47546.1 - 4.1e-27 95.0 46.5 4.1e-27 95.0 46.5 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Synthase_beta PF11421.8 KXG47547.1 - 0.096 13.4 0.6 0.42 11.4 0.0 2.1 2 0 0 2 2 2 0 ATP synthase F1 beta subunit PGA_cap PF09587.10 KXG47548.1 - 5.3e-69 232.5 0.0 6.3e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap SH3_7 PF12914.7 KXG47548.1 - 0.027 14.7 0.0 0.065 13.4 0.0 1.7 1 0 0 1 1 1 0 SH3 domain of SH3b2 type GATA PF00320.27 KXG47549.1 - 3.9e-28 96.8 17.5 2.2e-14 52.8 6.1 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KXG47549.1 - 1.1e-05 24.9 2.7 0.0059 16.1 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KXG47549.1 - 0.00012 22.1 2.5 0.1 12.8 0.2 2.8 2 0 0 2 2 2 2 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KXG47549.1 - 0.0003 20.6 3.7 0.075 13.0 0.4 2.5 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 KXG47549.1 - 0.0014 18.7 6.4 0.023 14.8 0.5 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 KXG47549.1 - 0.013 15.4 4.2 1.9 8.4 0.3 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Ribosomal_S27e PF01667.17 KXG47549.1 - 0.054 13.2 0.9 2.6 7.8 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein S27 ArfGap PF01412.18 KXG47549.1 - 0.065 13.3 3.6 0.54 10.3 0.1 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DZR PF12773.7 KXG47549.1 - 0.071 13.1 12.5 1.1 9.3 0.3 3.0 2 1 0 2 2 2 0 Double zinc ribbon CCDC-167 PF15188.6 KXG47549.1 - 0.079 13.3 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Nudix_N_2 PF14803.6 KXG47549.1 - 6.6 6.7 11.4 10 6.2 2.7 3.5 2 1 0 2 2 2 0 Nudix N-terminal COPI_assoc PF08507.10 KXG47550.1 - 5.8e-32 110.5 5.9 6.2e-32 110.4 5.9 1.0 1 0 0 1 1 1 1 COPI associated protein Cytochrom_B558a PF05038.13 KXG47550.1 - 0.2 11.2 1.1 0.35 10.4 1.1 1.3 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Cg6151-P PF10233.9 KXG47550.1 - 2.5 8.5 7.9 6.9 7.0 7.6 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein CG6151-P MFS_1 PF07690.16 KXG47551.1 - 9.9e-40 136.5 30.1 2.2e-35 122.2 23.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXG47551.1 - 8.4e-08 31.2 13.5 7.5e-06 24.7 3.0 2.7 4 0 0 4 4 4 2 MFS/sugar transport protein MFS_3 PF05977.13 KXG47551.1 - 0.028 12.8 15.0 0.0077 14.7 3.8 2.9 3 1 0 3 3 3 0 Transmembrane secretion effector OATP PF03137.20 KXG47551.1 - 3.2 5.9 10.7 0.14 10.4 1.5 2.5 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DAO PF01266.24 KXG47552.1 - 2.8e-35 122.6 0.1 3.7e-35 122.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXG47552.1 - 1.7e-05 24.2 0.0 4.3e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KXG47552.1 - 0.00018 21.7 0.0 0.00047 20.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF1296 PF06972.11 KXG47553.1 - 0.0052 16.9 0.6 0.024 14.8 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1296) CUE PF02845.16 KXG47553.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 CUE domain OTU PF02338.19 KXG47553.1 - 0.033 14.7 0.0 0.059 13.9 0.0 1.4 1 0 0 1 1 1 0 OTU-like cysteine protease DMA PF03474.14 KXG47553.1 - 0.078 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 DMRTA motif DUF1053 PF06327.14 KXG47553.1 - 0.09 13.3 3.5 0.38 11.3 0.0 3.0 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1053) DcpS_C PF11969.8 KXG47553.1 - 0.11 13.0 0.0 0.27 11.7 0.0 1.7 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Cep3 PF16846.5 KXG47553.1 - 0.29 9.6 0.8 0.4 9.1 0.8 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Not3 PF04065.15 KXG47553.1 - 2 7.8 11.2 15 4.9 0.3 2.8 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component GATase PF00117.28 KXG47554.1 - 4.5e-11 42.9 0.0 6.4e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KXG47554.1 - 0.013 15.1 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.16 KXG47555.1 - 4.1e-41 141.1 52.8 1.1e-32 113.3 27.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG47555.1 - 6.8e-11 41.7 18.0 6.8e-11 41.7 18.0 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXG47555.1 - 6.3e-09 34.8 14.2 6.3e-09 34.8 14.2 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KXG47555.1 - 2.3e-06 26.5 5.8 2.3e-06 26.5 5.8 3.5 2 1 2 4 4 4 3 MFS/sugar transport protein WD40 PF00400.32 KXG47556.1 - 8.8e-09 35.9 14.5 0.043 14.7 0.3 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat Fungal_trans_2 PF11951.8 KXG47556.1 - 9.3e-09 34.6 1.2 6.1e-08 31.9 0.0 2.3 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG47556.1 - 0.00058 19.9 10.1 0.0011 19.1 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tautomerase PF01361.21 KXG47556.1 - 0.023 14.6 0.3 0.046 13.6 0.3 1.4 1 0 0 1 1 1 0 Tautomerase enzyme ANAPC4_WD40 PF12894.7 KXG47556.1 - 0.046 14.0 0.1 6.1 7.2 0.0 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DEAD PF00270.29 KXG47557.1 - 2.9e-44 150.9 0.1 4.3e-44 150.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG47557.1 - 2.3e-18 66.6 0.0 9.7e-18 64.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXG47557.1 - 3.4e-17 62.4 0.1 6.9e-17 61.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXG47557.1 - 3.8e-06 27.0 0.2 1.2e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXG47557.1 - 0.041 13.1 0.4 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase FAM176 PF14851.6 KXG47557.1 - 0.16 11.7 4.6 0.21 11.3 0.1 2.9 3 0 0 3 3 3 0 FAM176 family CENP-B_dimeris PF09026.10 KXG47557.1 - 1.9 8.9 6.5 8.1 6.9 3.5 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pantoate_ligase PF02569.15 KXG47558.1 - 3e-92 308.6 0.0 3.5e-92 308.4 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase ATP-sulfurylase PF01747.17 KXG47558.1 - 0.094 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 ATP-sulfurylase Acyltransferase PF01553.21 KXG47559.1 - 2.4e-16 59.6 0.0 4.3e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Cellulase PF00150.18 KXG47561.1 - 5.6e-16 58.8 2.9 7.1e-16 58.5 2.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KXG47561.1 - 0.00022 21.0 0.5 0.0003 20.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_2_C PF02836.17 KXG47561.1 - 0.0011 18.2 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KXG47561.1 - 0.012 14.9 0.1 0.026 13.9 0.1 1.5 2 0 0 2 2 2 0 Beta-galactosidase AP_endonuc_2 PF01261.24 KXG47561.1 - 0.028 13.9 0.0 0.51 9.7 0.0 2.1 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Filament PF00038.21 KXG47562.1 - 0.00056 19.6 64.2 0.00085 19.0 48.7 2.6 1 1 1 2 2 2 2 Intermediate filament protein DUF3584 PF12128.8 KXG47562.1 - 0.19 9.2 66.5 0.026 12.1 6.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF4972 PF16342.5 KXG47562.1 - 1.3 8.7 12.9 0.17 11.6 7.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4972) Methyltransf_16 PF10294.9 KXG47564.1 - 0.0067 16.2 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Cys_Met_Meta_PP PF01053.20 KXG47565.1 - 7.1e-140 465.9 0.1 8.1e-140 465.7 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXG47565.1 - 1e-09 38.0 0.2 1.6e-09 37.5 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXG47565.1 - 4.1e-07 29.6 0.2 7e-07 28.9 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KXG47565.1 - 3.4e-06 26.3 1.2 5.5e-06 25.6 0.5 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXG47565.1 - 0.0015 17.9 0.1 0.0026 17.1 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase RNA_pol_Rbc25 PF08292.12 KXG47566.1 - 2.5e-36 124.8 2.0 7.9e-36 123.1 2.0 1.7 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KXG47566.1 - 5.3e-14 52.3 0.0 7.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KXG47566.1 - 0.12 12.7 0.0 0.26 11.7 0.0 1.5 2 0 0 2 2 2 0 S1 RNA binding domain NUFIP1 PF10453.9 KXG47567.1 - 6.2e-17 61.2 2.0 6.2e-17 61.2 2.0 3.2 4 0 0 4 4 4 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 KXG47567.1 - 1.9e-08 34.0 4.7 3.9e-08 33.0 4.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXG47567.1 - 1e-05 25.4 7.8 1.7e-05 24.7 7.8 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KXG47567.1 - 5.7e-05 22.8 4.5 9.1e-05 22.2 4.5 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KXG47567.1 - 0.0002 22.0 0.1 0.0002 22.0 0.1 2.7 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 KXG47567.1 - 0.41 11.2 5.7 0.77 10.3 5.7 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Exonuc_VII_L PF02601.15 KXG47567.1 - 2.3 7.7 15.8 3.6 7.1 15.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 KXG47567.1 - 9.3 5.0 10.2 13 4.5 10.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GPI-anchored PF10342.9 KXG47568.1 - 3.2e-22 79.1 1.9 3.2e-22 79.1 1.9 2.7 2 1 0 2 2 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KXG47568.1 - 0.00012 21.9 4.4 0.00019 21.2 4.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Big_3_4 PF13754.6 KXG47568.1 - 0.0038 16.9 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function SOG2 PF10428.9 KXG47568.1 - 0.068 12.4 16.5 0.074 12.2 16.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF572 PF04502.13 KXG47568.1 - 0.24 11.0 6.4 0.29 10.7 6.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SPICE PF15678.5 KXG47568.1 - 0.24 10.7 11.0 0.3 10.4 11.0 1.0 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression Raftlin PF15250.6 KXG47568.1 - 0.82 8.4 7.0 1 8.0 7.0 1.0 1 0 0 1 1 1 0 Raftlin Macoilin PF09726.9 KXG47568.1 - 3.6 6.0 12.1 4 5.9 12.1 1.1 1 0 0 1 1 1 0 Macoilin family CCDC106 PF15794.5 KXG47568.1 - 4.2 7.0 9.4 6 6.5 9.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF5427 PF10310.9 KXG47568.1 - 6.4 5.6 12.2 8.2 5.3 12.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Apt1 PF10351.9 KXG47568.1 - 6.6 5.5 14.5 8.1 5.2 14.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain NAD_binding_9 PF13454.6 KXG47570.1 - 7.7e-09 35.7 0.0 1.2e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXG47570.1 - 1.1e-08 34.6 0.0 3.7e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG47570.1 - 0.0022 17.2 0.0 0.026 13.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXG47570.1 - 0.0044 16.3 0.0 0.058 12.6 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KXG47571.1 - 1.4e-16 60.6 0.0 2.2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG47571.1 - 2.3e-07 30.4 0.0 3.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RRM_1 PF00076.22 KXG47573.1 - 1.3e-05 25.0 0.0 0.021 14.7 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.11 KXG47574.1 - 1.3e-20 74.3 0.7 1.3e-20 74.3 0.7 2.2 2 0 0 2 2 2 1 Sds3-like SUIM_assoc PF16619.5 KXG47574.1 - 0.00038 20.4 8.3 0.0013 18.7 8.3 1.9 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF1487 PF07368.11 KXG47574.1 - 0.29 10.6 0.4 2 7.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1487) Ank_2 PF12796.7 KXG47575.1 - 1.9e-13 50.8 0.7 1.7e-06 28.5 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG47575.1 - 8.5e-13 48.5 0.2 6e-05 23.5 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) NACHT PF05729.12 KXG47575.1 - 4.3e-10 39.8 0.0 1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.6 KXG47575.1 - 1.2e-08 34.5 0.4 0.062 13.9 0.0 5.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KXG47575.1 - 3.2e-06 27.3 1.2 3.1 8.4 0.1 5.2 4 0 0 4 4 4 1 Ankyrin repeat AAA_16 PF13191.6 KXG47575.1 - 3.6e-06 27.5 0.2 1.6e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXG47575.1 - 8.2e-06 26.1 0.0 7.4e-05 23.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Ank_5 PF13857.6 KXG47575.1 - 1.5e-05 25.1 0.8 0.015 15.6 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) NACHT_N PF17100.5 KXG47575.1 - 0.0044 16.9 0.0 0.0099 15.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase KAP_NTPase PF07693.14 KXG47575.1 - 0.018 14.3 0.8 0.091 12.0 0.2 2.3 1 1 0 2 2 2 0 KAP family P-loop domain PIF1 PF05970.14 KXG47575.1 - 0.086 12.0 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_19 PF13245.6 KXG47575.1 - 0.16 12.3 0.0 0.42 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 KXG47576.1 - 2.5e-24 85.8 0.8 3.6e-24 85.2 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain 3HCDH_N PF02737.18 KXG47577.1 - 1.3e-31 109.8 0.0 1.9e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXG47577.1 - 5.3e-09 36.6 0.0 1.1e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 KXG47577.1 - 1.4e-05 25.1 0.0 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF5050 PF16472.5 KXG47577.1 - 0.00019 20.8 0.0 0.24 10.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF5050) NAD_binding_2 PF03446.15 KXG47577.1 - 0.00071 19.8 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase SGL PF08450.12 KXG47577.1 - 0.0014 18.3 0.1 1.9 8.0 0.0 3.3 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region 2-Hacid_dh_C PF02826.19 KXG47577.1 - 0.031 13.6 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXG47577.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_1 PF00175.21 KXG47578.1 - 3.1e-32 111.4 0.0 6.2e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXG47578.1 - 1.7e-28 98.9 0.0 4.4e-28 97.5 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KXG47578.1 - 1.4e-22 79.6 0.2 3.3e-22 78.4 0.2 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KXG47578.1 - 1.1e-05 25.6 0.0 0.0005 20.2 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KXG47578.1 - 0.01 16.1 0.0 3.8 7.7 0.0 2.5 1 1 1 2 2 2 0 Siderophore-interacting FAD-binding domain p450 PF00067.22 KXG47579.1 - 5.9e-67 226.4 0.0 7e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3453 PF11935.8 KXG47580.1 - 2.5e-71 239.9 0.3 9.6e-71 238.0 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Coiled-coil_56 PF09813.9 KXG47581.1 - 2e-05 24.6 0.0 2.1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 STT3 PF02516.14 KXG47582.1 - 3.9e-143 477.9 33.8 3.6e-138 461.6 32.1 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Glucan_synthase PF02364.15 KXG47582.1 - 0.12 10.5 0.1 0.17 10.0 0.1 1.2 1 0 0 1 1 1 0 1,3-beta-glucan synthase component CSN8_PSD8_EIF3K PF10075.9 KXG47583.1 - 3e-32 111.6 0.0 4.3e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SDH_sah PF01972.16 KXG47583.1 - 0.12 11.3 0.0 0.64 9.0 0.0 2.0 2 0 0 2 2 2 0 Serine dehydrogenase proteinase SAC3_GANP PF03399.16 KXG47583.1 - 0.17 11.2 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 SAC3/GANP family ATP-synt_E PF05680.12 KXG47584.1 - 3.3e-26 91.4 0.6 3.7e-26 91.3 0.6 1.0 1 0 0 1 1 1 1 ATP synthase E chain Adhesin_P1_N PF18652.1 KXG47584.1 - 0.02 14.9 2.7 0.03 14.3 2.7 1.5 1 1 0 1 1 1 0 Adhesin P1 N-terminal domain FCH PF00611.23 KXG47584.1 - 0.025 14.8 1.4 0.025 14.8 1.4 1.4 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Chordopox_A13L PF05961.11 KXG47584.1 - 0.074 13.3 1.8 0.17 12.1 0.7 1.9 1 1 1 2 2 2 0 Chordopoxvirus A13L protein WD40 PF00400.32 KXG47585.1 - 0.00062 20.5 9.7 0.6 11.1 0.0 5.4 5 1 0 5 5 5 3 WD domain, G-beta repeat MFS_1 PF07690.16 KXG47586.1 - 4.3e-30 104.8 33.7 4.3e-30 104.8 33.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KXG47586.1 - 0.34 10.7 6.6 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Pkinase PF00069.25 KXG47587.1 - 8.3e-30 104.0 0.0 1.1e-13 51.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG47587.1 - 1.1e-08 34.8 0.0 0.00033 20.0 0.0 3.0 3 1 0 3 3 3 2 Protein tyrosine kinase PMT PF02366.18 KXG47590.1 - 2e-87 292.9 16.5 3.2e-87 292.2 16.5 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXG47590.1 - 1.3e-66 224.0 2.1 1.3e-66 224.0 2.1 2.9 2 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXG47590.1 - 8.6e-21 74.6 0.1 1.3e-20 74.0 0.1 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KXG47590.1 - 1.9 8.7 20.3 0.07 13.4 9.5 3.6 4 1 0 4 4 4 0 Dolichyl-phosphate-mannose-protein mannosyltransferase YL1 PF05764.13 KXG47591.1 - 0.00098 19.3 2.3 0.00098 19.3 2.3 2.1 2 0 0 2 2 2 1 YL1 nuclear protein Nucleo_P87 PF07267.11 KXG47591.1 - 0.083 11.7 5.4 0.17 10.7 5.4 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FancD2 PF14631.6 KXG47591.1 - 1.9 5.8 4.9 2.6 5.4 4.9 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease CDC45 PF02724.14 KXG47591.1 - 3.2 5.9 7.5 6.3 5.0 7.5 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF1764 PF08576.10 KXG47591.1 - 9.8 7.1 11.2 0.61 11.0 5.3 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) RNA_pol_L_2 PF13656.6 KXG47592.1 - 1e-25 89.3 0.0 1.8e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KXG47592.1 - 6e-11 41.6 0.0 1e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain EF-hand_4 PF12763.7 KXG47593.1 - 1.6e-26 92.2 0.0 2.9e-14 52.9 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 KXG47593.1 - 1.3e-08 34.3 0.7 3.1e-08 33.2 0.7 1.7 1 0 0 1 1 1 1 WH2 motif DUF1720 PF08226.11 KXG47593.1 - 1.5e-08 34.9 86.1 3.6e-06 27.3 43.7 8.0 6 1 1 7 7 7 4 Domain of unknown function (DUF1720) EF-hand_7 PF13499.6 KXG47593.1 - 0.053 14.0 0.0 0.053 14.0 0.0 3.4 4 0 0 4 4 4 0 EF-hand domain pair EF-hand_1 PF00036.32 KXG47593.1 - 0.079 12.5 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 EF hand MFS_1 PF07690.16 KXG47594.1 - 4.9e-37 127.7 40.1 4.9e-37 127.7 40.1 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM40 PF15817.5 KXG47594.1 - 0.1 12.4 0.8 0.35 10.6 0.8 2.0 1 0 0 1 1 1 0 Transmembrane protein 40 family Fungal_trans PF04082.18 KXG47595.1 - 3.4e-13 49.2 5.9 4.7e-13 48.8 5.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3629 PF12302.8 KXG47595.1 - 0.033 13.6 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) TFR_dimer PF04253.15 KXG47595.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain Na_Ca_ex PF01699.24 KXG47596.1 - 9.3e-51 171.7 43.6 2.7e-28 98.8 17.3 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Cnd2 PF05786.14 KXG47597.1 - 0 1028.9 3.4 0 1028.7 3.4 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KXG47597.1 - 0.045 14.0 1.5 0.065 13.4 0.0 2.0 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal MARVEL PF01284.23 KXG47598.1 - 4.7e-05 23.4 5.5 0.00023 21.2 3.3 2.2 2 0 0 2 2 2 1 Membrane-associating domain DUF1218 PF06749.12 KXG47598.1 - 0.033 14.7 0.5 0.033 14.7 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) FixQ PF05545.11 KXG47598.1 - 0.11 12.5 6.7 1.1 9.2 0.7 2.9 2 1 1 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Phage_Gp23 PF10669.9 KXG47598.1 - 0.13 12.6 0.7 2.6 8.4 0.4 2.4 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) EphA2_TM PF14575.6 KXG47598.1 - 0.16 12.9 0.3 6.1 7.8 0.0 3.1 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Cation_efflux PF01545.21 KXG47598.1 - 0.77 9.4 4.5 0.18 11.5 0.4 1.8 2 0 0 2 2 2 0 Cation efflux family DUF202 PF02656.15 KXG47598.1 - 6.3 7.3 10.2 1.3 9.6 0.6 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF202) zf-H2C2_2 PF13465.6 KXG47599.1 - 1.1e-11 44.6 16.7 1.9e-06 28.1 1.9 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXG47599.1 - 6.4e-10 38.9 21.4 0.00086 19.6 4.7 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXG47599.1 - 6.3e-07 29.7 19.0 0.021 15.6 3.7 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXG47599.1 - 2.1e-06 27.5 15.9 0.0055 16.7 0.0 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 KXG47599.1 - 0.0045 17.3 9.0 0.012 15.9 5.5 2.6 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 KXG47599.1 - 0.0078 16.3 6.5 0.018 15.1 1.7 2.5 2 0 0 2 2 2 1 Zinc ribbon domain Rad50_zn_hook PF04423.14 KXG47599.1 - 0.011 15.5 2.1 0.23 11.3 0.3 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_9 PF16293.5 KXG47599.1 - 0.014 15.3 1.7 2.9 7.8 0.2 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KXG47599.1 - 0.041 13.8 0.9 0.041 13.8 0.9 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2HE PF16278.5 KXG47599.1 - 0.054 14.0 14.5 0.11 13.0 1.6 3.1 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DZR PF12773.7 KXG47599.1 - 0.092 12.8 6.7 0.81 9.8 6.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.19 KXG47599.1 - 0.17 11.9 2.7 0.47 10.5 2.7 1.6 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 KXG47599.1 - 0.43 10.9 4.0 27 5.1 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon zf-C2H2_jaz PF12171.8 KXG47599.1 - 0.44 10.9 12.2 0.4 11.0 1.2 3.7 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.9 KXG47599.1 - 0.47 10.6 5.7 5.4 7.2 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger domain zinc-ribbons_6 PF07191.12 KXG47599.1 - 1.4 9.0 5.0 5.7 7.0 5.0 1.9 1 1 0 1 1 1 0 zinc-ribbons zf-FPG_IleRS PF06827.14 KXG47599.1 - 1.6 8.7 6.4 2 8.3 0.6 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-ISL3 PF14690.6 KXG47599.1 - 3 8.6 9.5 11 6.8 0.3 3.3 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_ribbon_SprT PF17283.2 KXG47599.1 - 6 6.9 11.7 13 5.8 0.8 2.5 1 1 2 3 3 3 0 SprT-like zinc ribbon domain Stk19 PF10494.9 KXG47602.1 - 5.8e-70 235.8 0.0 8.4e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DUF3074 PF11274.8 KXG47602.1 - 1.9e-33 116.0 0.0 2.8e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Glyco_transf_20 PF00982.21 KXG47603.1 - 5.4e-159 529.9 0.0 7.4e-159 529.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KXG47603.1 - 1.4e-36 125.8 0.1 2.4e-36 125.0 0.1 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase CAS_CSE1 PF03378.15 KXG47603.1 - 0.13 10.7 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus RTA1 PF04479.13 KXG47604.1 - 2.8e-54 183.9 11.1 2.8e-54 183.9 11.1 1.5 1 1 1 2 2 2 1 RTA1 like protein DUF2721 PF11026.8 KXG47604.1 - 6.4 6.7 13.4 6 6.8 1.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) 4HBT_3 PF13622.6 KXG47605.1 - 4.8e-51 174.4 1.2 5.5e-51 174.2 1.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KXG47606.1 - 6.3e-08 32.9 0.0 1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily eIF3m_C_helix PF18005.1 KXG47608.1 - 2.7e-11 42.9 3.2 7.7e-11 41.5 3.2 1.8 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 KXG47608.1 - 5.2e-11 43.0 0.0 1.3e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 PCI domain T3SSipB PF16535.5 KXG47608.1 - 6.2 7.3 8.1 5.1 7.6 1.6 2.7 3 0 0 3 3 3 0 Type III cell invasion protein SipB ADK PF00406.22 KXG47609.1 - 2.6e-42 144.5 0.0 3.4e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXG47609.1 - 1.5e-32 112.9 0.0 2.1e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXG47609.1 - 6.8e-08 33.1 0.0 9.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXG47609.1 - 1.8e-07 31.4 0.0 3.9e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KXG47609.1 - 2.3e-06 27.4 0.0 0.018 14.7 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Ploopntkinase3 PF18751.1 KXG47609.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 FSH1 PF03959.13 KXG47610.1 - 4.1e-20 72.3 0.0 8.4e-20 71.3 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Cutinase PF01083.22 KXG47610.1 - 4.1e-12 46.4 0.0 4.4e-09 36.5 0.1 3.1 3 0 0 3 3 3 2 Cutinase ketoacyl-synt PF00109.26 KXG47611.1 - 3.4e-69 233.2 0.0 7.4e-69 232.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXG47611.1 - 1.2e-62 211.0 0.1 4.1e-62 209.3 0.1 2.0 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KXG47611.1 - 2.6e-51 175.0 0.0 4.5e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXG47611.1 - 4.3e-49 167.4 0.0 6.2e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KXG47611.1 - 1.4e-38 131.6 0.1 5.6e-38 129.6 0.1 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KXG47611.1 - 2.1e-16 61.2 0.0 7.6e-16 59.4 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KXG47611.1 - 3e-16 59.9 0.0 8.8e-16 58.4 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KXG47611.1 - 9.5e-16 57.8 0.1 2.3e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KXG47611.1 - 1.3e-12 47.8 0.0 4.9e-12 45.9 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KXG47611.1 - 2.1e-11 43.9 0.1 4.9e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KXG47611.1 - 1.2e-06 28.3 0.1 2.6e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KXG47611.1 - 1.6e-06 28.4 1.2 4.5e-06 26.9 1.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAT PF16073.5 KXG47611.1 - 0.00032 20.5 0.3 0.0024 17.7 0.3 2.1 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thiolase_N PF00108.23 KXG47611.1 - 0.01 15.2 0.1 0.023 14.1 0.1 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain YjeF_N PF03853.15 KXG47611.1 - 0.033 14.1 0.1 11 5.9 0.0 2.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus ACP_syn_III PF08545.10 KXG47611.1 - 0.056 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NmrA PF05368.13 KXG47611.1 - 0.18 11.3 0.1 0.4 10.2 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family Hexokinase_2 PF03727.16 KXG47612.1 - 2.1e-58 197.6 0.0 3.1e-58 197.1 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXG47612.1 - 2.1e-46 158.3 0.0 3.1e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase NmrA PF05368.13 KXG47614.1 - 3.4e-41 141.3 0.0 9e-41 139.9 0.0 1.7 2 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KXG47614.1 - 2.5e-11 43.8 0.0 3.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXG47614.1 - 4.9e-06 26.2 0.0 8.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KXG47614.1 - 0.00014 22.1 0.0 0.00026 21.2 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 KXG47614.1 - 0.0016 17.5 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KXG47614.1 - 0.0088 16.3 0.0 0.031 14.5 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KXG47614.1 - 0.021 15.2 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KXG47614.1 - 0.026 14.5 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 KXG47614.1 - 0.032 13.7 0.0 0.095 12.1 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase adh_short_C2 PF13561.6 KXG47614.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Arylsulfotran_2 PF14269.6 KXG47615.1 - 4.7e-42 144.4 1.2 1.2e-41 143.1 1.3 1.6 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXG47615.1 - 3.7e-11 42.6 1.8 2.1e-10 40.1 1.9 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) NAD_binding_1 PF00175.21 KXG47616.1 - 2.1e-27 95.9 0.0 3.5e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXG47616.1 - 1.9e-15 57.0 0.0 3.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXG47616.1 - 3.2e-08 33.8 0.0 0.00016 21.9 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain CDO_I PF05995.12 KXG47617.1 - 5.8e-39 133.1 0.0 7.7e-39 132.7 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KXG47617.1 - 0.0035 16.8 0.1 0.0054 16.2 0.1 1.5 1 1 0 1 1 1 1 PCO_ADO Fungal_trans PF04082.18 KXG47618.1 - 4.6e-15 55.4 0.3 8.3e-15 54.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MinC_N PF05209.13 KXG47618.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain DUF2458 PF10454.9 KXG47619.1 - 3.7e-65 218.8 0.3 4.7e-65 218.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Ndc1_Nup PF09531.10 KXG47619.1 - 0.045 12.5 4.3 0.045 12.4 4.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ATG16 PF08614.11 KXG47619.1 - 5.2 7.2 8.7 3.3 7.9 2.8 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) COX14 PF14880.6 KXG47620.1 - 2.8e-19 68.7 0.2 2.8e-19 68.7 0.2 2.3 3 0 0 3 3 3 1 Cytochrome oxidase c assembly ECM11 PF15463.6 KXG47620.1 - 0.0019 18.8 0.2 0.0064 17.1 0.0 1.9 2 0 0 2 2 2 1 Extracellular mutant protein 11 Phage_GPD PF05954.11 KXG47620.1 - 0.027 13.8 0.3 0.054 12.8 0.3 1.5 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) DAHP_synth_1 PF00793.20 KXG47621.1 - 1.2e-98 329.4 0.0 1.4e-98 329.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family RNase_H PF00075.24 KXG47623.1 - 3.5e-11 43.5 0.0 5.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KXG47623.1 - 0.00052 19.8 0.0 0.72 9.7 0.0 2.7 3 0 0 3 3 3 2 Reverse transcriptase-like Thiolase_N PF00108.23 KXG47624.1 - 5.2e-73 245.6 0.2 7e-73 245.2 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXG47624.1 - 7.7e-44 148.3 1.6 1.4e-43 147.5 0.8 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXG47624.1 - 0.016 14.8 1.3 0.057 13.0 0.1 2.3 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain Polysacc_deac_2 PF04748.13 KXG47624.1 - 0.045 12.9 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Ribosomal_L50 PF10501.9 KXG47625.1 - 2.5e-11 43.7 0.1 3.7e-11 43.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal subunit 39S Rtf2 PF04641.12 KXG47626.1 - 9.9e-64 215.2 2.6 1.9e-63 214.3 2.6 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KXG47626.1 - 1.4e-09 37.6 0.4 0.0018 18.0 0.0 2.9 2 1 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KXG47626.1 - 0.0011 19.0 0.6 0.0034 17.4 0.1 2.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXG47626.1 - 0.0026 17.7 0.1 0.0026 17.7 0.1 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-NOSIP PF15906.5 KXG47626.1 - 0.028 14.6 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 KXG47626.1 - 0.076 12.9 0.2 0.19 11.6 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Plasmodium_Vir PF05795.11 KXG47626.1 - 0.35 10.2 3.2 0.54 9.6 3.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Prok-RING_4 PF14447.6 KXG47626.1 - 0.41 10.5 3.1 1.2 9.1 0.3 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF3827 PF12877.7 KXG47626.1 - 2.4 6.4 6.2 4.1 5.7 6.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3827) PRKCSH-like PF12999.7 KXG47627.1 - 1.1e-43 149.1 5.8 2.7e-27 95.7 1.8 3.5 4 0 0 4 4 4 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KXG47627.1 - 1e-34 119.4 4.1 2.7e-34 118.1 0.6 2.4 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KXG47627.1 - 6.2e-08 33.5 0.3 2.3e-07 31.7 0.3 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRCC PF10253.9 KXG47627.1 - 0.027 15.2 1.4 0.048 14.4 0.3 1.9 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Fib_alpha PF08702.10 KXG47627.1 - 0.061 13.5 7.6 1.1 9.4 0.1 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family ATG27 PF09451.10 KXG47627.1 - 0.07 13.0 0.3 0.07 13.0 0.3 1.8 2 0 0 2 2 2 0 Autophagy-related protein 27 GTP-bdg_M PF16360.5 KXG47627.1 - 1.3 9.7 8.5 0.33 11.6 3.9 2.5 2 1 0 2 2 2 0 GTP-binding GTPase Middle Region NTP_transf_2 PF01909.23 KXG47628.1 - 7.9e-11 42.1 0.0 1.7e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KXG47628.1 - 9.6e-08 32.1 0.7 2.7e-07 30.7 0.7 1.8 1 1 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 KXG47628.1 - 0.065 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase zf-CCCH_8 PF18633.1 KXG47628.1 - 0.089 12.9 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 Bravo_FIGEY PF13882.6 KXG47628.1 - 0.17 13.3 0.0 0.17 13.3 0.0 2.5 3 0 0 3 3 3 0 Bravo-like intracellular region Aldo_ket_red PF00248.21 KXG47629.1 - 2.4e-66 223.9 0.0 3.4e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pam16 PF03656.13 KXG47630.1 - 6.8e-31 106.9 0.4 8.2e-31 106.7 0.4 1.0 1 0 0 1 1 1 1 Pam16 Pex24p PF06398.11 KXG47631.1 - 8.8e-101 337.5 0.5 1.2e-100 337.1 0.5 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Wzy_C PF04932.15 KXG47631.1 - 0.13 11.9 1.8 0.97 9.0 1.8 2.1 1 1 0 1 1 1 0 O-Antigen ligase Pkinase_Tyr PF07714.17 KXG47632.1 - 6.6e-05 22.3 0.1 0.00029 20.2 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXG47632.1 - 0.00052 19.5 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KXG47633.1 - 6.6e-43 145.2 1.2 1.4e-12 48.0 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Pkinase PF00069.25 KXG47633.1 - 5.2e-32 111.3 0.0 7.7e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.6 KXG47633.1 - 7.6e-29 96.6 0.1 2.4e-05 24.4 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KXG47633.1 - 2.3e-27 94.2 0.1 6.4e-05 23.2 0.0 6.7 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 KXG47633.1 - 3.9e-26 91.1 0.6 4.4e-09 36.7 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG47633.1 - 3.5e-24 84.5 1.2 2.2e-06 27.8 0.1 4.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KXG47633.1 - 1.4e-13 50.8 0.0 2.3e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG47633.1 - 1.8e-09 37.4 0.0 3.5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like AnkUBD PF18418.1 KXG47633.1 - 0.0061 16.7 0.0 0.41 10.8 0.0 2.9 3 0 0 3 3 3 1 Ankyrin ubiquitin-binding domain Pkinase_fungal PF17667.1 KXG47633.1 - 0.023 13.5 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Sugar_tr PF00083.24 KXG47634.1 - 9.1e-05 21.5 0.1 0.00011 21.2 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG47634.1 - 0.00023 20.2 7.5 0.00023 20.2 7.5 1.5 1 1 0 2 2 2 1 Major Facilitator Superfamily SNARE_assoc PF09335.11 KXG47634.1 - 0.088 13.3 3.6 0.053 14.0 1.8 1.6 2 1 0 2 2 2 0 SNARE associated Golgi protein G3P_acyltransf PF02660.15 KXG47634.1 - 0.14 12.2 2.5 0.25 11.4 2.5 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase LptF_LptG PF03739.14 KXG47634.1 - 0.72 8.6 3.9 1.1 8.0 3.9 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG MFS_1 PF07690.16 KXG47635.1 - 5.2e-35 121.0 33.7 7.3e-35 120.5 33.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KXG47636.1 - 6.9e-43 146.9 0.0 8.6e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cu_amine_oxid PF01179.20 KXG47637.1 - 2.1e-164 547.4 3.6 2.5e-164 547.1 3.6 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KXG47637.1 - 0.0018 18.4 0.1 0.0036 17.5 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Presenilin PF01080.17 KXG47638.1 - 0.0041 15.9 1.7 0.0053 15.6 1.7 1.2 1 0 0 1 1 1 1 Presenilin Apt1 PF10351.9 KXG47638.1 - 0.0065 15.4 10.7 0.0074 15.2 10.7 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain Transformer PF06495.11 KXG47638.1 - 0.02 15.0 2.1 0.02 15.0 2.1 2.2 2 0 0 2 2 2 0 Fruit fly transformer protein Alpha_GJ PF03229.13 KXG47638.1 - 0.027 15.0 7.3 0.027 15.0 7.3 3.3 2 1 1 3 3 3 0 Alphavirus glycoprotein J SID-1_RNA_chan PF13965.6 KXG47638.1 - 0.028 12.9 0.8 0.034 12.6 0.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Macoilin PF09726.9 KXG47638.1 - 0.091 11.3 9.2 0.11 11.0 9.2 1.2 1 0 0 1 1 1 0 Macoilin family SpoIIIAH PF12685.7 KXG47638.1 - 0.18 11.6 17.5 0.31 10.8 17.5 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Miga PF10265.9 KXG47638.1 - 0.37 9.7 6.3 0.48 9.3 6.3 1.2 1 0 0 1 1 1 0 Mitoguardin TRAP_alpha PF03896.16 KXG47638.1 - 0.51 9.5 3.9 0.93 8.6 3.3 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit GCOM2 PF15328.6 KXG47638.1 - 0.69 10.2 11.5 1.1 9.6 11.5 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 Peptidase_S64 PF08192.11 KXG47638.1 - 1.2 7.5 11.2 1.4 7.3 11.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 PA26 PF04636.13 KXG47638.1 - 2.8 6.8 6.4 3.7 6.4 6.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FAM176 PF14851.6 KXG47638.1 - 4.2 7.0 7.1 2.1e+02 1.5 0.0 2.6 2 1 0 2 2 2 0 FAM176 family Med13_C PF06333.12 KXG47638.1 - 5.1 6.3 19.0 0.58 9.4 11.6 2.1 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain MCM_bind PF09739.9 KXG47638.1 - 7.7 4.8 9.9 11 4.3 9.9 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor ATP-synt_S1 PF05827.12 KXG47639.1 - 0.0001 22.2 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) OAD_gamma PF04277.13 KXG47639.1 - 0.056 14.0 0.4 0.097 13.3 0.4 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Nop25 PF09805.9 KXG47640.1 - 5.5e-38 130.5 16.7 5.5e-38 130.5 16.7 2.8 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) Tropomyosin_1 PF12718.7 KXG47641.1 - 1.1e-48 165.0 36.2 1.3e-48 164.7 36.2 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KXG47641.1 - 2.5e-09 36.9 35.9 0.0001 21.8 14.5 2.8 1 1 1 2 2 2 2 Tropomyosin Uso1_p115_C PF04871.13 KXG47641.1 - 0.0011 19.3 37.3 0.012 16.0 15.1 2.1 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.9 KXG47641.1 - 0.0024 17.9 5.6 0.0024 17.9 5.6 2.9 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CASP_C PF08172.12 KXG47641.1 - 0.0085 15.5 19.1 0.15 11.4 0.9 2.1 2 0 0 2 2 2 2 CASP C terminal KASH_CCD PF14662.6 KXG47641.1 - 0.0087 15.9 22.6 0.0087 15.9 22.6 2.2 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH KLRAQ PF10205.9 KXG47641.1 - 0.01 16.0 23.9 0.021 15.0 10.0 2.8 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein GAS PF13851.6 KXG47641.1 - 0.018 14.4 32.3 0.21 10.9 23.1 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KXG47641.1 - 0.032 13.1 33.7 0.19 10.6 12.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.12 KXG47641.1 - 0.039 14.0 20.4 0.16 12.0 6.9 2.1 1 1 1 2 2 2 0 Laminin Domain II ATG16 PF08614.11 KXG47641.1 - 0.045 14.0 34.9 0.68 10.1 14.5 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 KXG47641.1 - 0.096 12.8 32.5 2.7 8.1 13.8 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.6 KXG47641.1 - 0.11 12.9 33.6 0.34 11.3 15.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) MPS2 PF17060.5 KXG47641.1 - 0.16 11.2 18.1 0.28 10.4 18.1 1.4 1 1 0 1 1 1 0 Monopolar spindle protein 2 DUF3450 PF11932.8 KXG47641.1 - 0.23 10.7 29.4 0.077 12.3 5.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DHR10 PF18595.1 KXG47641.1 - 0.25 11.4 36.6 1.9 8.5 13.4 2.6 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain bZIP_1 PF00170.21 KXG47641.1 - 0.38 10.9 30.0 4.8 7.3 0.1 4.3 2 1 2 4 4 4 0 bZIP transcription factor Fez1 PF06818.15 KXG47641.1 - 0.41 11.1 28.7 2.1 8.8 21.0 2.0 1 1 1 2 2 2 0 Fez1 DUF724 PF05266.14 KXG47641.1 - 0.6 9.9 26.6 0.43 10.4 9.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 KXG47641.1 - 0.64 10.1 15.9 3.4 7.7 2.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fmp27_WPPW PF10359.9 KXG47641.1 - 0.74 8.6 27.1 0.16 10.7 11.7 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain UPF0242 PF06785.11 KXG47641.1 - 0.79 9.8 33.9 2.6 8.1 13.6 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Nup54 PF13874.6 KXG47641.1 - 0.92 9.6 27.6 1.4 9.0 9.3 3.1 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 MAD PF05557.13 KXG47641.1 - 0.98 7.7 31.7 0.61 8.4 20.6 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein Jnk-SapK_ap_N PF09744.9 KXG47641.1 - 1 9.6 33.9 2.6 8.3 23.4 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 KXG47641.1 - 1.2 9.6 41.3 1.1 9.8 22.6 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region NABP PF07990.12 KXG47641.1 - 1.3 8.5 7.1 1.4 8.3 7.1 1.2 1 0 0 1 1 1 0 Nucleic acid binding protein NABP ZapB PF06005.12 KXG47641.1 - 1.3 9.5 39.6 2.6e+02 2.1 18.1 3.8 1 1 1 2 2 2 0 Cell division protein ZapB SlyX PF04102.12 KXG47641.1 - 1.6 9.4 26.3 2 9.1 2.4 3.9 1 1 3 4 4 4 0 SlyX DUF4407 PF14362.6 KXG47641.1 - 1.7 7.9 25.3 3.2 7.0 25.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) BRE1 PF08647.11 KXG47641.1 - 1.8 8.7 32.2 8.3 6.6 9.2 3.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Atg14 PF10186.9 KXG47641.1 - 1.9 7.5 25.6 0.93 8.5 10.6 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lebercilin PF15619.6 KXG47641.1 - 1.9 8.1 35.1 1.5 8.4 16.1 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TMF_TATA_bd PF12325.8 KXG47641.1 - 2.1 8.6 29.3 17 5.6 20.9 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 KXG47641.1 - 2.3 8.3 38.4 1.5 8.9 13.9 2.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.6 KXG47641.1 - 2.9 8.1 35.4 2.6 8.2 3.3 4.1 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 PspA_IM30 PF04012.12 KXG47641.1 - 2.9 7.4 34.6 1.2 8.7 4.3 2.2 1 1 1 2 2 2 0 PspA/IM30 family FlaC_arch PF05377.11 KXG47641.1 - 3.5 8.1 19.2 7.1 7.1 3.7 4.3 1 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 KXG47641.1 - 5.2 7.6 22.2 60 4.2 8.8 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 bZIP_2 PF07716.15 KXG47641.1 - 5.3 7.2 36.2 5.9 7.1 4.5 5.1 2 2 4 6 6 6 0 Basic region leucine zipper DUF2203 PF09969.9 KXG47641.1 - 6.2 7.6 21.4 6 7.6 6.9 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF5320 PF17253.2 KXG47641.1 - 6.4 7.9 22.4 4 8.6 4.9 3.3 3 1 0 3 3 3 0 Family of unknown function (DUF5320) YabA PF06156.13 KXG47641.1 - 7.1 7.3 26.0 23 5.7 0.4 2.9 1 1 1 2 2 1 0 Initiation control protein YabA TMF_DNA_bd PF12329.8 KXG47641.1 - 7.7 6.6 36.9 0.85 9.7 14.0 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding CHDCT2 PF08074.11 KXG47641.1 - 7.7 6.7 12.4 2.6 8.2 6.7 2.0 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain DUF641 PF04859.12 KXG47641.1 - 7.9 6.8 23.4 0.51 10.7 6.1 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF812 PF05667.11 KXG47641.1 - 8.8 5.1 30.5 13 4.6 30.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) VGPC1_C PF16799.5 KXG47641.1 - 9.3 6.3 14.3 0.45 10.5 3.2 3.1 2 1 1 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 PHtD_u1 PF16645.5 KXG47642.1 - 0.019 15.4 0.3 0.019 15.4 0.3 2.1 2 0 0 2 2 2 0 Unstructured region on Pneumococcal histidine triad protein Draxin PF15550.6 KXG47642.1 - 0.57 10.0 5.7 0.35 10.7 3.4 1.8 1 1 0 1 1 1 0 Draxin CMAS PF02353.20 KXG47643.1 - 3.2e-61 207.0 0.0 3.9e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KXG47643.1 - 8.1e-10 39.3 0.0 1.6e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG47643.1 - 5e-09 36.2 0.0 8.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG47643.1 - 1.2e-08 35.5 0.0 2.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG47643.1 - 2.1e-05 25.2 0.0 4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KXG47643.1 - 0.0054 16.3 0.0 0.009 15.6 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 KXG47643.1 - 0.0082 15.7 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KXG47643.1 - 0.066 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KXG47643.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MetW PF07021.12 KXG47643.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 KXG47643.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain EXS PF03124.14 KXG47644.1 - 2.8e-100 335.9 15.6 3.2e-100 335.7 15.6 1.0 1 0 0 1 1 1 1 EXS family 7TM_GPCR_Srd PF10317.9 KXG47644.1 - 0.082 12.1 0.5 0.95 8.6 0.1 2.3 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd Pex2_Pex12 PF04757.14 KXG47645.1 - 2.2e-46 158.3 5.8 3e-46 157.8 5.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KXG47645.1 - 3.3e-11 42.9 8.6 5.4e-11 42.1 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXG47645.1 - 2.9e-10 39.8 5.5 4.5e-10 39.2 5.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXG47645.1 - 5.3e-10 39.0 6.6 8.2e-10 38.4 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXG47645.1 - 9e-10 38.7 9.4 1.4e-09 38.1 9.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXG47645.1 - 1.4e-08 34.6 3.6 1.4e-08 34.6 3.6 1.6 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXG47645.1 - 3.9e-07 29.8 6.4 6.5e-07 29.1 6.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXG47645.1 - 6.3e-07 29.3 6.2 1.1e-06 28.5 6.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXG47645.1 - 2.6e-05 24.4 6.5 5.3e-05 23.4 6.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KXG47645.1 - 7.3e-05 22.9 8.3 0.00013 22.0 8.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KXG47645.1 - 0.011 15.6 3.0 0.02 14.8 3.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KXG47645.1 - 0.026 14.7 5.8 0.044 13.9 5.8 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KXG47645.1 - 0.071 13.2 3.2 0.14 12.2 2.9 1.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KXG47645.1 - 0.16 11.8 6.4 0.34 10.7 6.4 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 KXG47645.1 - 4 7.7 7.4 10 6.5 7.4 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DNA_pol_A_exo1 PF01612.20 KXG47646.1 - 2.2e-19 69.8 0.0 3.5e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease LSM PF01423.22 KXG47647.1 - 4e-20 71.3 0.1 4.4e-20 71.1 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXG47647.1 - 0.11 12.7 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain adh_short PF00106.25 KXG47648.1 - 3.3e-12 46.3 0.3 4.4e-12 45.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG47648.1 - 1.2e-10 41.4 0.1 1.4e-10 41.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KXG47648.1 - 3.1e-06 27.2 0.4 6.9e-06 26.1 0.4 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXG47648.1 - 3.9e-06 26.6 1.4 3.9e-06 26.6 1.4 1.7 2 1 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 KXG47648.1 - 0.00086 18.8 0.1 0.0013 18.2 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXG47648.1 - 0.0034 17.3 0.1 0.0051 16.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 KXG47648.1 - 0.008 16.6 0.2 0.03 14.8 0.2 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DUF1776 PF08643.10 KXG47648.1 - 0.021 14.2 0.0 0.073 12.4 0.0 1.7 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 KXG47648.1 - 0.039 13.4 0.1 0.062 12.7 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 KXG47648.1 - 0.081 13.1 1.2 0.15 12.2 0.7 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus AA_permease PF00324.21 KXG47649.1 - 2e-147 491.7 40.9 2.4e-147 491.4 40.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG47649.1 - 1.1e-35 123.3 39.3 1.4e-35 122.9 39.3 1.1 1 0 0 1 1 1 1 Amino acid permease RhoGAP PF00620.27 KXG47650.1 - 8.8e-16 58.1 0.2 2.2e-15 56.8 0.2 1.6 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 KXG47650.1 - 2.7e-08 33.8 0.0 5.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KXG47650.1 - 6.2e-08 32.8 0.0 1.8e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Phage_TAC_8 PF10666.9 KXG47650.1 - 0.035 14.4 1.1 0.2 12.0 0.2 2.4 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Gp14 ()A118 Amidohydro_2 PF04909.14 KXG47651.1 - 1.1e-15 58.2 0.7 2.5e-15 57.0 0.1 1.7 2 0 0 2 2 2 1 Amidohydrolase WD40 PF00400.32 KXG47652.1 - 6.3e-89 289.5 32.2 1.9e-11 44.3 0.0 10.4 10 1 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG47652.1 - 1e-40 137.9 0.0 4.9e-05 23.5 0.0 9.2 2 2 7 9 9 9 8 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXG47652.1 - 3.9e-17 62.2 0.2 0.075 12.0 0.1 8.7 1 1 7 8 8 8 5 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KXG47652.1 - 3.6e-10 39.3 6.0 1.1 9.0 0.0 7.9 8 0 0 8 8 8 3 Proteasome subunit A N-terminal signature Nup160 PF11715.8 KXG47652.1 - 2.5e-09 36.4 9.4 0.087 11.4 0.0 6.9 4 3 3 8 8 8 4 Nucleoporin Nup120/160 PD40 PF07676.12 KXG47652.1 - 1.6e-07 31.1 6.4 5.2 7.1 0.0 8.3 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KXG47652.1 - 1.2e-06 28.1 0.0 0.53 9.6 0.0 4.5 2 1 4 6 6 6 2 WD40-like domain PALB2_WD40 PF16756.5 KXG47652.1 - 4.1e-05 22.7 9.0 4 6.3 0.0 7.0 1 1 7 9 9 9 2 Partner and localizer of BRCA2 WD40 domain Nbas_N PF15492.6 KXG47652.1 - 0.00047 19.6 6.2 11 5.2 0.0 5.6 1 1 2 6 6 6 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 KXG47652.1 - 0.00069 18.2 0.0 0.19 10.2 0.0 3.3 2 2 1 3 3 3 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 KXG47652.1 - 0.0097 14.7 0.0 2.9 6.5 0.0 3.9 3 2 2 5 5 5 1 Nup133 N terminal like Frtz PF11768.8 KXG47652.1 - 0.045 12.1 0.0 10 4.3 0.0 3.5 2 1 3 5 5 5 0 WD repeat-containing and planar cell polarity effector protein Fritz IKI3 PF04762.12 KXG47652.1 - 0.076 11.0 0.0 1.7 6.5 0.0 2.8 2 1 1 3 3 3 0 IKI3 family TruB_C PF09142.11 KXG47652.1 - 0.12 12.1 0.2 1.2e+02 2.6 0.0 4.7 6 0 0 6 6 6 0 tRNA Pseudouridine synthase II, C terminal FCP1_C PF09309.10 KXG47652.1 - 0.15 11.9 0.0 75 3.1 0.0 4.3 5 0 0 5 5 5 0 FCP1, C-terminal Me-amine-dh_H PF06433.11 KXG47652.1 - 0.17 10.7 0.0 39 3.0 0.0 3.4 4 1 1 5 5 5 0 Methylamine dehydrogenase heavy chain (MADH) adh_short_C2 PF13561.6 KXG47653.1 - 5e-54 183.3 0.0 6.2e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG47653.1 - 6.5e-43 146.5 0.2 8.2e-43 146.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG47653.1 - 2e-10 40.9 0.6 3.2e-10 40.2 0.6 1.2 1 0 0 1 1 1 1 KR domain LOR PF04525.12 KXG47654.1 - 1.2e-10 41.3 0.0 1.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 LURP-one-related MR_MLE_C PF13378.6 KXG47655.1 - 2.2e-40 138.6 0.0 2.9e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KXG47655.1 - 1.5e-09 38.1 0.0 2.5e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.18 KXG47656.1 - 1.2e-24 86.8 0.2 1.7e-24 86.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 KXG47657.1 - 3.8e-68 229.7 0.0 5.2e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG47657.1 - 2.5e-49 167.9 0.0 4.5e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG47657.1 - 1.8e-05 24.2 0.0 0.00071 19.0 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXG47657.1 - 0.00019 20.3 0.0 0.00033 19.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Thioredoxin_7 PF13899.6 KXG47658.1 - 1.6e-16 60.3 0.0 2.9e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KXG47658.1 - 1.6e-14 53.4 0.1 7.4e-14 51.3 0.0 2.1 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.20 KXG47658.1 - 1e-08 35.2 0.0 7.5e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 UBX domain Thioredoxin_2 PF13098.6 KXG47658.1 - 0.071 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredox_DsbH PF03190.15 KXG47658.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 AAA PF00004.29 KXG47659.1 - 5.7e-11 43.0 0.0 6.2e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXG47659.1 - 1.4e-09 38.6 0.1 4e-09 37.1 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXG47659.1 - 1.1e-08 35.5 0.0 2.6e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 KXG47659.1 - 8.6e-08 32.1 0.0 3.5e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 KXG47659.1 - 7.2e-05 22.8 0.0 0.00022 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA lid domain NTPase_1 PF03266.15 KXG47659.1 - 0.0014 18.6 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_7 PF12775.7 KXG47659.1 - 0.0016 18.0 0.0 0.0037 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region KTI12 PF08433.10 KXG47659.1 - 0.0019 17.7 0.3 0.78 9.1 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 Rad17 PF03215.15 KXG47659.1 - 0.0067 16.4 0.2 0.027 14.4 0.0 2.1 2 1 0 2 2 2 1 Rad17 P-loop domain PIF1 PF05970.14 KXG47659.1 - 0.007 15.6 0.0 0.022 13.9 0.0 1.7 2 0 0 2 2 2 1 PIF1-like helicase TIP49 PF06068.13 KXG47659.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 KXG47659.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 KXG47659.1 - 0.017 14.3 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KXG47659.1 - 0.018 15.4 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 KXG47659.1 - 0.047 14.0 0.0 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KXG47659.1 - 0.09 12.5 0.0 0.31 10.7 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 KXG47659.1 - 0.11 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FtsJ PF01728.19 KXG47660.1 - 5.2e-12 46.2 0.0 7.8e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DVL PF08137.12 KXG47661.1 - 2.9 7.9 4.3 0.7 9.8 0.9 1.7 2 0 0 2 2 2 0 DVL family D-ser_dehydrat PF14031.6 KXG47662.1 - 3.5e-27 94.9 0.7 1e-26 93.4 0.1 2.1 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KXG47662.1 - 1.4e-12 47.8 0.0 2.1e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain LDB19 PF13002.7 KXG47663.1 - 1.7e-57 194.3 0.0 2.7e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 KXG47663.1 - 4.1e-08 33.4 0.0 1.9e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain PIG-L PF02585.17 KXG47665.1 - 9.8e-29 100.6 0.0 1.3e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP13 PF12921.7 KXG47666.1 - 1.5e-22 79.6 0.3 3.4e-22 78.5 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial ATPase expression PPR_3 PF13812.6 KXG47666.1 - 1.8e-08 34.3 0.0 0.0017 18.4 0.0 3.0 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 KXG47666.1 - 0.0036 17.5 0.0 5 7.4 0.0 3.1 3 0 0 3 3 3 2 PPR repeat family LSM PF01423.22 KXG47667.1 - 4.1e-19 68.0 0.2 5.2e-19 67.7 0.2 1.2 1 0 0 1 1 1 1 LSM domain GTP_EFTU PF00009.27 KXG47668.1 - 3.4e-18 65.9 0.0 5.6e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXG47668.1 - 3.3e-07 30.6 2.0 1.2e-06 28.8 2.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KXG47668.1 - 2.6e-05 24.5 0.0 6.4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.9 KXG47668.1 - 0.012 15.4 0.4 1.2 8.9 0.0 3.0 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KXG47668.1 - 0.037 14.1 0.1 0.098 12.8 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Peptidase_S64 PF08192.11 KXG47670.1 - 0.14 10.6 0.1 0.25 9.8 0.1 1.3 1 0 0 1 1 1 0 Peptidase family S64 SNF2_N PF00176.23 KXG47671.1 - 2.4e-69 233.7 0.0 3.4e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KXG47671.1 - 5.6e-24 83.9 0.0 1.6e-23 82.4 0.0 1.9 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KXG47671.1 - 2.7e-13 50.2 0.0 6.2e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG47671.1 - 0.00018 21.6 0.0 0.00041 20.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 KXG47671.1 - 0.00025 20.8 9.0 0.00044 20.1 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXG47671.1 - 0.00095 19.0 7.8 0.0022 17.8 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXG47671.1 - 0.0045 17.3 11.2 0.013 15.9 11.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXG47671.1 - 0.0052 16.8 10.2 0.011 15.8 10.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXG47671.1 - 0.0071 16.2 12.1 0.014 15.2 12.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXG47671.1 - 0.017 15.1 10.8 0.032 14.2 10.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXG47671.1 - 1.8 8.8 10.9 3.8 7.7 10.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SQS_PSY PF00494.19 KXG47672.1 - 4.6e-48 164.0 0.0 6e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase CorA PF01544.18 KXG47673.1 - 1.2e-24 87.2 6.7 2e-17 63.4 0.6 3.3 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 KXG47674.1 - 4.4e-31 108.1 28.1 5.7e-30 104.4 26.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DNApol_Exo PF18136.1 KXG47675.1 - 6.1e-94 314.3 0.1 9.9e-94 313.6 0.1 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KXG47675.1 - 1.1e-53 182.6 0.0 1.7e-53 182.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A zf-C3HC4_3 PF13920.6 KXG47676.1 - 0.052 13.4 1.1 0.078 12.9 1.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0052 PF01933.18 KXG47677.1 - 3.2e-61 207.1 0.0 4.1e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 MFS_1 PF07690.16 KXG47678.1 - 4.3e-19 68.6 26.8 4.1e-17 62.2 17.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TPT PF03151.16 KXG47679.1 - 6.1e-26 91.4 21.8 7.4e-26 91.2 21.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXG47679.1 - 8.2e-05 21.9 19.8 0.0015 17.8 19.8 2.2 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXG47679.1 - 0.64 10.2 36.3 2.7 8.2 11.5 2.4 2 0 0 2 2 2 0 EamA-like transporter family Methyltransf_PK PF05891.12 KXG47680.1 - 6.9e-69 231.7 0.0 8e-69 231.5 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KXG47680.1 - 0.00016 22.3 0.1 0.00038 21.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG47680.1 - 0.00089 19.1 0.0 0.0015 18.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG47680.1 - 0.0098 16.5 0.1 0.018 15.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain CitG PF01874.16 KXG47680.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase Amidohydro_1 PF01979.20 KXG47681.1 - 0.00011 21.7 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family SRR1 PF07985.12 KXG47681.1 - 0.083 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 SRR1 PhyH PF05721.13 KXG47682.1 - 7.9e-09 36.1 0.1 1.3e-08 35.3 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KXG47682.1 - 4e-08 32.4 0.1 0.00033 19.5 0.1 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) Fungal_trans PF04082.18 KXG47682.1 - 0.00029 20.0 1.0 0.00052 19.1 0.4 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain DUF4246 PF14033.6 KXG47683.1 - 1.7e-141 472.5 0.4 2.3e-112 376.4 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 KXG47683.1 - 0.0069 16.8 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase F-box-like PF12937.7 KXG47684.1 - 0.00018 21.3 0.8 0.00034 20.4 0.8 1.5 1 0 0 1 1 1 1 F-box-like TRP PF06011.12 KXG47685.1 - 0.0029 16.4 27.8 0.0064 15.3 1.9 2.4 2 1 0 2 2 2 2 Transient receptor potential (TRP) ion channel F-box-like PF12937.7 KXG47686.1 - 2.5e-05 24.0 0.2 5.9e-05 22.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like Asp PF00026.23 KXG47687.1 - 1.7e-74 251.1 4.3 2.1e-74 250.8 4.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXG47687.1 - 8.5e-08 32.6 1.7 0.0011 19.2 0.4 3.0 2 2 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXG47687.1 - 2.4e-05 24.9 0.9 0.028 15.1 0.3 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KXG47687.1 - 0.0063 16.3 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Zn_clus PF00172.18 KXG47688.1 - 0.0016 18.5 5.5 0.0026 17.8 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PriC PF07445.12 KXG47688.1 - 0.025 14.5 0.1 0.042 13.8 0.1 1.3 1 0 0 1 1 1 0 Primosomal replication protein priC Atg14 PF10186.9 KXG47689.1 - 8.8e-17 61.2 18.6 6.6e-15 55.0 0.2 2.4 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KXG47689.1 - 1.6e-10 40.4 1.7 0.00097 18.1 0.1 3.3 3 0 0 3 3 3 3 Vacuolar protein sorting 38 APG6 PF04111.12 KXG47689.1 - 0.027 14.4 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Apg6 BARA domain DUF3958 PF13125.6 KXG47689.1 - 6.6 7.0 11.5 0.48 10.7 3.2 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF3958) Mhr1 PF12829.7 KXG47690.1 - 4.1e-29 100.5 0.4 9.5e-29 99.3 0.4 1.7 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination PP2C PF00481.21 KXG47691.1 - 8.2e-64 215.7 0.2 6.4e-52 176.7 0.2 3.2 1 1 1 2 2 2 2 Protein phosphatase 2C APH PF01636.23 KXG47692.1 - 6.7e-08 32.7 1.0 1.2e-07 31.9 0.2 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG47692.1 - 0.031 13.9 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pro_isomerase PF00160.21 KXG47693.1 - 1.2e-40 139.4 0.0 2.2e-40 138.5 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 KXG47693.1 - 8.6e-05 22.6 0.0 0.00052 20.1 0.0 2.3 1 1 1 2 2 2 1 U-box domain zf-NOSIP PF15906.5 KXG47693.1 - 0.00023 21.2 0.0 0.00051 20.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 KXG47693.1 - 0.00054 19.4 0.0 0.0029 17.0 0.0 2.1 1 1 0 1 1 1 1 Rtf2 RING-finger YjeF_N PF03853.15 KXG47694.1 - 1.6e-43 148.6 0.2 2.3e-43 148.0 0.2 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KXG47694.1 - 2.4e-06 28.3 2.0 2.9e-06 28.1 0.2 2.0 2 0 0 2 2 2 1 FDF domain NTP_transferase PF00483.23 KXG47694.1 - 0.19 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase PIF1 PF05970.14 KXG47695.1 - 8.6e-66 222.6 0.0 9.2e-51 173.1 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KXG47695.1 - 1.5e-24 86.8 0.0 2.5e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXG47695.1 - 1.5e-12 48.1 0.0 2.7e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXG47695.1 - 2.7e-06 27.7 0.0 7.8e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KXG47695.1 - 6.8e-05 23.2 0.2 0.039 14.4 0.0 2.9 2 1 0 2 2 2 1 RNA helicase Herpes_Helicase PF02689.14 KXG47695.1 - 8.5e-05 20.7 0.0 0.001 17.1 0.0 2.4 3 0 0 3 3 3 1 Helicase AAA_7 PF12775.7 KXG47695.1 - 8.7e-05 22.1 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KXG47695.1 - 0.00046 20.6 0.0 0.001 19.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.6 KXG47695.1 - 0.0019 18.0 0.1 0.0058 16.4 0.1 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KXG47695.1 - 0.0033 17.0 0.1 0.0033 17.0 0.1 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 KXG47695.1 - 0.0039 17.6 0.1 0.008 16.6 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KXG47695.1 - 0.017 14.4 0.0 0.042 13.1 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KXG47695.1 - 0.021 14.0 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain SH3_13 PF18335.1 KXG47695.1 - 0.024 14.5 0.0 0.073 12.9 0.0 1.8 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain T2SSE PF00437.20 KXG47695.1 - 0.025 13.7 0.0 0.053 12.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 KXG47695.1 - 0.031 13.7 0.1 0.14 11.6 0.0 2.0 1 1 0 2 2 2 0 PhoH-like protein RsgA_GTPase PF03193.16 KXG47695.1 - 0.038 13.9 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ResIII PF04851.15 KXG47695.1 - 0.045 13.7 0.4 0.14 12.2 0.3 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF5605 PF18310.1 KXG47695.1 - 0.058 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) NACHT PF05729.12 KXG47695.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TrwB_AAD_bind PF10412.9 KXG47695.1 - 0.074 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 KXG47695.1 - 0.076 13.5 0.2 0.6 10.6 0.0 2.6 3 0 0 3 3 2 0 ABC transporter Helicase_RecD PF05127.14 KXG47695.1 - 0.087 12.7 0.2 0.39 10.6 0.2 2.0 1 1 0 1 1 1 0 Helicase ATPase_2 PF01637.18 KXG47695.1 - 0.09 12.7 0.5 0.46 10.4 0.5 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KXG47695.1 - 0.097 12.7 0.4 1.1 9.2 0.4 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KXG47695.1 - 0.11 12.3 0.0 0.11 12.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain PTCB-BRCT PF12738.7 KXG47696.1 - 5e-51 170.5 0.6 1.3e-22 79.5 0.1 4.3 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 KXG47696.1 - 4.7e-31 107.0 0.6 3.1e-14 53.1 0.1 4.8 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXG47696.1 - 2.8e-15 56.5 0.0 0.00032 21.0 0.0 4.4 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KXG47696.1 - 5.1e-07 29.9 2.6 0.046 14.0 0.0 4.3 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KXG47696.1 - 0.025 14.7 0.0 12 6.1 0.0 3.6 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Dynamin_N PF00350.23 KXG47697.1 - 2.4e-17 63.5 0.0 5.2e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KXG47697.1 - 1.7e-10 40.9 0.0 2.1e-09 37.4 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXG47697.1 - 3.3e-07 30.0 0.2 9.4e-06 25.3 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF883 PF05957.13 KXG47697.1 - 0.03 14.9 1.1 29 5.4 0.0 3.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) IIGP PF05049.13 KXG47697.1 - 0.045 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) TsaE PF02367.17 KXG47697.1 - 0.049 13.6 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KXG47697.1 - 0.053 13.1 0.9 0.65 9.6 0.6 2.6 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.26 KXG47697.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2205 PF10224.9 KXG47697.1 - 0.075 13.0 0.1 0.22 11.5 0.1 1.8 1 0 0 1 1 1 0 Short coiled-coil protein AAA_18 PF13238.6 KXG47697.1 - 0.08 13.5 0.0 0.3 11.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXG47697.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Snf7 PF03357.21 KXG47698.1 - 3.5e-27 95.1 28.7 1.2e-19 70.6 14.3 2.8 2 1 1 3 3 3 2 Snf7 YlqD PF11068.8 KXG47698.1 - 0.18 12.2 13.6 1.1 9.7 2.1 2.2 2 0 0 2 2 2 0 YlqD protein DUF3000 PF11452.8 KXG47699.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) APH PF01636.23 KXG47700.1 - 2e-13 50.8 0.0 3.1e-13 50.2 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG47700.1 - 0.00079 19.1 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KXG47700.1 - 0.001 18.7 0.0 0.023 14.3 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.14 KXG47700.1 - 0.034 13.4 0.0 0.2 10.8 0.0 1.9 2 0 0 2 2 2 0 Fructosamine kinase Pkinase PF00069.25 KXG47701.1 - 9e-10 38.4 0.1 0.00017 21.0 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG47701.1 - 1e-05 24.9 0.1 0.00059 19.2 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 KXG47701.1 - 0.0077 15.8 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 RIO1 family TIM PF00121.18 KXG47703.1 - 8.9e-92 306.8 0.8 1e-91 306.7 0.8 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 KXG47703.1 - 0.015 14.8 0.1 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 CutC family MDM10 PF12519.8 KXG47704.1 - 1.6e-149 498.7 3.1 8.2e-128 427.2 4.7 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 RL10P_insert PF17777.1 KXG47705.1 - 5.9e-21 74.3 0.0 1.1e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KXG47705.1 - 1.7e-18 66.6 0.0 3.7e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.8 KXG47706.1 - 1.5e-25 89.6 2.6 3.2e-25 88.6 2.6 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KXG47706.1 - 7.8e-16 57.7 0.1 1.4e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXG47706.1 - 2.4e-05 24.4 0.0 5.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif L51_S25_CI-B8 PF05047.16 KXG47707.1 - 6.4e-15 54.8 0.2 9.2e-15 54.3 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF3328 PF11807.8 KXG47708.1 - 4.7e-42 144.3 0.0 5.1e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) ABC_tran PF00005.27 KXG47709.1 - 1.6e-45 155.0 0.0 5.8e-25 88.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXG47709.1 - 9e-15 55.0 8.3 9e-15 55.0 8.3 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KXG47709.1 - 6.1e-13 48.7 2.1 0.0049 16.3 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXG47709.1 - 4.1e-10 40.0 1.1 0.015 15.1 0.0 4.0 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXG47709.1 - 7.7e-08 32.0 1.6 0.0025 17.5 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KXG47709.1 - 4.5e-07 30.6 2.8 0.0097 16.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXG47709.1 - 1.6e-06 28.1 0.1 0.028 14.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXG47709.1 - 3.4e-06 27.6 0.1 0.0093 16.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXG47709.1 - 7.6e-06 26.2 2.1 0.014 15.6 0.1 3.0 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 KXG47709.1 - 7.4e-05 21.9 0.2 0.0027 16.8 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KXG47709.1 - 0.00022 20.7 1.5 0.45 9.8 0.1 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KXG47709.1 - 0.00057 19.9 0.5 0.52 10.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Sigma54_activat PF00158.26 KXG47709.1 - 0.001 18.8 0.2 1.3 8.7 0.0 2.8 3 0 0 3 3 3 2 Sigma-54 interaction domain ATPase_2 PF01637.18 KXG47709.1 - 0.0026 17.7 0.1 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KXG47709.1 - 0.0028 17.4 1.4 6.2 6.5 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF87 PF01935.17 KXG47709.1 - 0.0037 17.4 2.2 1.1 9.3 0.3 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain cobW PF02492.19 KXG47709.1 - 0.0061 16.2 0.7 0.2 11.3 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KXG47709.1 - 0.0068 15.6 0.2 8 5.6 0.1 3.1 3 0 0 3 3 3 0 NB-ARC domain AAA_30 PF13604.6 KXG47709.1 - 0.009 15.7 0.5 0.19 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.15 KXG47709.1 - 0.014 14.2 1.2 0.12 11.2 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein NACHT PF05729.12 KXG47709.1 - 0.018 14.9 0.5 3.2 7.6 0.0 2.6 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.13 KXG47709.1 - 0.022 13.9 0.1 0.29 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KXG47709.1 - 0.032 14.6 0.3 1.6 9.2 0.1 2.6 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 KXG47709.1 - 0.038 13.5 1.8 0.91 9.0 0.1 2.6 2 1 0 2 2 2 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 KXG47709.1 - 0.057 12.7 0.2 0.5 9.6 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain Dynamin_N PF00350.23 KXG47709.1 - 0.074 13.1 4.1 0.85 9.7 0.0 2.8 3 0 0 3 3 2 0 Dynamin family AAA_15 PF13175.6 KXG47709.1 - 0.081 12.6 0.7 7.9 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.7 KXG47709.1 - 0.09 11.7 0.4 3.8 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain Mg_chelatase PF01078.21 KXG47709.1 - 0.092 12.1 0.5 3 7.2 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_27 PF13514.6 KXG47709.1 - 0.15 11.6 0.0 0.64 9.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXG47709.1 - 0.97 8.7 2.8 2.7 7.2 0.1 2.6 4 0 0 4 4 3 0 Zeta toxin zf-RING_UBOX PF13445.6 KXG47710.1 - 0.00078 19.4 2.6 0.0016 18.5 2.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXG47710.1 - 0.0011 19.3 1.6 0.0021 18.4 1.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXG47710.1 - 0.0023 17.8 5.7 0.0037 17.2 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain FYVE PF01363.21 KXG47710.1 - 0.004 17.2 2.3 0.007 16.5 2.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger Prok-RING_4 PF14447.6 KXG47710.1 - 0.032 14.1 4.9 0.25 11.2 5.2 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KXG47710.1 - 0.044 13.6 4.0 0.13 12.1 4.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXG47710.1 - 0.063 13.1 4.3 0.22 11.4 4.3 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXG47710.1 - 0.3 11.0 8.4 1.7 8.6 8.5 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 KXG47710.1 - 0.51 10.6 6.6 3.6 7.9 1.4 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Prp19 PF08606.11 KXG47711.1 - 4.5e-31 106.6 1.3 7.3e-31 106.0 1.3 1.3 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 KXG47711.1 - 4.9e-13 49.2 0.5 2e-05 24.8 0.0 4.8 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXG47711.1 - 1.5e-12 47.8 3.2 0.00026 21.7 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat WD40_like PF17005.5 KXG47711.1 - 2.2e-08 33.8 0.1 4.7e-06 26.2 0.1 2.5 2 1 0 2 2 2 2 WD40-like domain Coatomer_WDAD PF04053.14 KXG47711.1 - 2.2e-08 33.6 0.6 0.0011 18.1 0.1 2.2 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.11 KXG47711.1 - 0.00048 20.1 0.2 0.0055 16.6 0.0 2.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A U-box PF04564.15 KXG47711.1 - 0.0043 17.2 0.0 0.0082 16.3 0.0 1.4 1 0 0 1 1 1 1 U-box domain Frtz PF11768.8 KXG47711.1 - 0.015 13.6 0.0 0.29 9.4 0.0 2.1 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KXG47711.1 - 0.051 12.5 0.1 0.18 10.7 0.1 1.9 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-Nse PF11789.8 KXG47711.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Mcl1_mid PF12341.8 KXG47711.1 - 0.095 12.0 0.0 0.27 10.5 0.0 1.7 1 1 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region V_ATPase_I_N PF18670.1 KXG47711.1 - 0.36 11.3 2.7 0.25 11.7 0.3 2.0 2 0 0 2 2 2 0 V-type ATPase subunit I, N-terminal domain DUF4604 PF15377.6 KXG47712.1 - 4.9e-19 69.4 19.0 5.6e-19 69.2 19.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) CDC45 PF02724.14 KXG47712.1 - 4.4 5.5 11.4 4.5 5.4 11.4 1.0 1 0 0 1 1 1 0 CDC45-like protein GTP_EFTU PF00009.27 KXG47713.1 - 3.6e-58 196.3 0.0 5.6e-58 195.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KXG47713.1 - 2.1e-15 56.5 0.0 6.2e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXG47713.1 - 9.9e-09 35.5 0.0 1.6e-07 31.6 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXG47713.1 - 1e-06 28.7 0.0 2.6e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KXG47713.1 - 0.0016 18.2 0.0 0.0082 15.9 0.0 2.2 2 1 1 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KXG47713.1 - 0.079 13.0 0.0 0.22 11.6 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase EXOSC1 PF10447.9 KXG47714.1 - 2.7e-28 98.7 4.2 3.9e-28 98.2 4.2 1.2 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KXG47714.1 - 2.2e-11 43.3 0.2 3.9e-11 42.6 0.2 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region DUF5567 PF17722.1 KXG47714.1 - 0.12 12.2 0.2 0.12 12.2 0.2 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5567) Arm PF00514.23 KXG47715.1 - 4.1e-74 242.6 30.2 2.9e-13 49.3 0.1 11.4 11 1 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KXG47715.1 - 2e-18 66.5 12.5 2.1e-05 24.9 0.2 8.3 8 2 1 9 9 9 5 HEAT-like repeat HEAT_2 PF13646.6 KXG47715.1 - 9.3e-17 61.2 9.0 5.8e-05 23.4 0.1 6.8 3 3 3 6 6 6 4 HEAT repeats HEAT PF02985.22 KXG47715.1 - 3.6e-16 57.9 14.0 0.34 11.3 0.0 9.0 10 0 0 10 10 8 5 HEAT repeat Arm_2 PF04826.13 KXG47715.1 - 1.3e-12 47.7 4.8 6.7e-08 32.3 1.3 2.5 1 1 1 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 KXG47715.1 - 1.6e-11 43.5 7.3 7e-07 28.2 0.9 2.7 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 KXG47715.1 - 4.6e-10 38.3 0.9 9.1e-10 37.3 0.6 1.6 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KXG47715.1 - 3.1e-09 36.6 0.8 6.1e-05 22.5 0.7 3.0 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 KXG47715.1 - 2.8e-05 24.2 7.5 0.067 13.2 0.1 5.1 2 2 3 6 6 6 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 KXG47715.1 - 9.9e-05 22.4 2.0 15 5.8 0.0 5.2 2 1 6 8 8 7 0 V-ATPase subunit H DUF3361 PF11841.8 KXG47715.1 - 0.00011 22.2 7.1 1.1 9.2 0.1 4.1 1 1 1 4 4 4 3 Domain of unknown function (DUF3361) DUF5578 PF17741.1 KXG47715.1 - 0.00033 20.2 6.9 2.8 7.3 0.0 5.2 2 1 3 6 6 6 2 Family of unknown function (DUF5578) IFRD PF05004.13 KXG47715.1 - 0.003 16.7 6.1 1.4 7.9 0.3 4.5 3 2 1 4 4 4 2 Interferon-related developmental regulator (IFRD) Atx10homo_assoc PF09759.9 KXG47715.1 - 0.0062 16.5 7.3 1.4 9.0 0.4 4.9 3 2 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain Vac14_Fab1_bd PF12755.7 KXG47715.1 - 0.012 16.1 0.1 2.5 8.8 0.0 3.6 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 KXG47715.1 - 0.028 15.1 6.1 27 5.8 0.3 6.2 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 KXG47715.1 - 0.029 14.3 1.7 1.7 8.6 0.6 3.2 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central FHA PF00498.26 KXG47716.1 - 4.6e-14 52.5 0.0 7.9e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXG47716.1 - 0.00029 21.1 0.0 0.0005 20.3 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain F-box-like_2 PF13013.6 KXG47718.1 - 0.052 13.5 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain NmrA PF05368.13 KXG47719.1 - 8.9e-12 45.1 0.0 1.2e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG47719.1 - 0.033 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Glyco_hydro_67M PF07488.12 KXG47719.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 middle domain Bestrophin PF01062.21 KXG47720.1 - 3.7e-43 148.0 0.0 4.5e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel AAA_lid_2 PF17863.1 KXG47721.1 - 8.2e-07 28.8 0.1 1.7e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 AAA lid domain Vps16_N PF04841.13 KXG47722.1 - 2.3e-98 329.6 0.0 3.2e-98 329.2 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KXG47722.1 - 2.8e-86 289.5 0.0 5.1e-86 288.6 0.0 1.4 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 KXG47722.1 - 0.002 18.4 0.0 0.23 11.8 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain CREPT PF16566.5 KXG47722.1 - 0.067 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Alb1 PF09135.11 KXG47723.1 - 3.4e-31 108.2 13.3 4.9e-31 107.7 13.3 1.2 1 0 0 1 1 1 1 Alb1 Dynamin_N PF00350.23 KXG47723.1 - 0.26 11.3 2.7 1.7 8.7 2.7 2.0 1 1 0 1 1 1 0 Dynamin family UCH PF00443.29 KXG47724.1 - 3.5e-32 111.9 0.0 6.5e-32 111.0 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXG47724.1 - 1.8e-06 27.8 0.8 1.3e-05 24.9 0.8 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase F-box PF00646.33 KXG47725.1 - 0.0021 17.9 0.1 0.0021 17.9 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXG47725.1 - 0.027 14.4 0.0 0.075 12.9 0.0 1.7 1 0 0 1 1 1 0 F-box-like DUF2020 PF09449.10 KXG47726.1 - 0.095 12.5 0.2 0.69 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2020) 2-Hacid_dh_C PF02826.19 KXG47727.1 - 1.2e-36 125.7 0.0 1.8e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXG47727.1 - 2.4e-19 69.4 0.0 3e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 KXG47727.1 - 0.027 14.1 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 KXG47727.1 - 0.13 12.4 1.8 0.27 11.3 0.3 2.2 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PUL PF08324.11 KXG47728.1 - 1.7e-66 224.3 0.6 2.3e-66 223.9 0.6 1.1 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 KXG47728.1 - 1.9e-42 144.7 0.0 4.6e-42 143.4 0.0 1.7 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 KXG47728.1 - 1.5e-14 53.8 0.0 3e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXG47728.1 - 0.00011 22.6 0.4 0.0033 17.9 0.4 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 KXG47728.1 - 0.00069 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KXG47728.1 - 0.018 15.1 0.0 0.053 13.6 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin domain AhpC-TSA PF00578.21 KXG47728.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family OST3_OST6 PF04756.13 KXG47728.1 - 0.083 12.2 0.0 0.16 11.3 0.0 1.5 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family Redoxin PF08534.10 KXG47728.1 - 0.14 11.9 0.1 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 Redoxin EF-hand_8 PF13833.6 KXG47729.1 - 0.0044 16.8 0.0 0.13 12.1 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KXG47729.1 - 0.011 15.6 0.1 0.79 9.8 0.0 3.4 4 1 0 4 4 4 0 EF-hand domain EF-hand_7 PF13499.6 KXG47729.1 - 0.012 16.0 0.0 2.4 8.7 0.0 3.1 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_9 PF14658.6 KXG47729.1 - 0.089 13.1 0.1 15 6.0 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain RuvA_C PF07499.13 KXG47729.1 - 0.096 13.2 0.0 0.34 11.4 0.0 2.0 1 1 0 1 1 1 0 RuvA, C-terminal domain RRM_1 PF00076.22 KXG47730.1 - 2.8e-14 52.7 0.0 4.4e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KXG47730.1 - 9.6e-06 26.1 1.3 9.6e-06 26.1 1.3 2.8 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 KXG47730.1 - 4e-05 23.4 0.0 6.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KXG47730.1 - 0.03 14.4 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Snf7 PF03357.21 KXG47731.1 - 6.8e-21 74.6 8.8 6.8e-21 74.6 8.8 1.8 2 0 0 2 2 2 1 Snf7 PSD4 PF07631.11 KXG47731.1 - 0.027 15.0 1.8 0.07 13.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1592) Gon7 PF08738.10 KXG47731.1 - 0.031 14.4 5.6 0.068 13.3 2.7 2.3 2 1 0 2 2 2 0 Gon7 family BMFP PF04380.13 KXG47731.1 - 0.07 13.6 9.3 0.71 10.4 1.5 3.8 2 1 1 3 3 3 0 Membrane fusogenic activity Snapin_Pallidin PF14712.6 KXG47731.1 - 8 7.0 10.3 1.9 9.0 3.9 2.7 3 1 0 3 3 3 0 Snapin/Pallidin CS PF04969.16 KXG47732.1 - 6.6e-07 30.3 0.0 1.1e-06 29.6 0.0 1.4 1 0 0 1 1 1 1 CS domain DFRP_C PF16543.5 KXG47733.1 - 3.9e-23 81.7 7.2 3.9e-23 81.7 7.2 3.9 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 KXG47733.1 - 2.4e-05 24.1 2.9 2.4e-05 24.1 2.9 2.7 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXG47733.1 - 0.00051 19.8 10.3 0.003 17.3 2.9 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 KXG47733.1 - 0.00062 20.4 6.2 0.00062 20.4 6.2 3.9 2 2 2 4 4 4 2 Torus domain zf_CCCH_4 PF18345.1 KXG47733.1 - 0.0055 16.7 7.4 0.0055 16.7 7.4 3.2 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH_3 PF15663.5 KXG47733.1 - 0.013 15.7 3.1 0.39 11.0 0.1 2.8 2 1 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KXG47733.1 - 0.66 10.5 16.0 0.45 11.1 4.7 3.0 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger T2SSM PF04612.12 KXG47733.1 - 3.4 7.7 7.6 0.97 9.5 3.2 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DAO PF01266.24 KXG47734.1 - 1.1e-29 104.1 0.1 1.3e-29 104.0 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 KXG47734.1 - 0.1 12.1 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Malic_M PF03949.15 KXG47734.1 - 0.15 11.3 0.6 0.82 8.9 0.1 2.0 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain SCF PF02404.15 KXG47736.1 - 0.23 10.8 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Stem cell factor adh_short PF00106.25 KXG47737.1 - 2.8e-24 85.7 0.1 3.4e-24 85.4 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG47737.1 - 2.1e-23 83.1 0.1 2.7e-23 82.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG47737.1 - 3.6e-06 27.0 0.1 5.4e-06 26.4 0.1 1.3 1 1 0 1 1 1 1 KR domain MlaE PF02405.16 KXG47737.1 - 0.13 12.0 0.3 0.3 10.8 0.1 1.6 2 0 0 2 2 2 0 Permease MlaE zf-HIT PF04438.16 KXG47738.1 - 4.7e-10 39.1 10.1 8.7e-10 38.3 10.1 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KXG47738.1 - 0.86 9.8 7.5 1.9 8.7 7.5 1.6 1 0 0 1 1 1 0 MYND finger Glyco_hydro_16 PF00722.21 KXG47739.1 - 0.0065 16.0 0.3 0.013 15.0 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Peptidase_C48 PF02902.19 KXG47740.1 - 6.8e-31 107.8 0.0 9.6e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PAP2 PF01569.21 KXG47741.1 - 2.3e-17 63.0 2.7 2.3e-17 63.0 2.7 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KXG47741.1 - 0.00035 20.3 7.3 0.00095 18.9 7.3 1.8 1 1 0 1 1 1 1 PAP2 superfamily Ras PF00071.22 KXG47742.1 - 1.5e-48 164.4 0.0 1.9e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXG47742.1 - 5.5e-21 75.0 0.0 8.4e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG47742.1 - 3.3e-05 23.4 0.0 0.00019 20.9 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 KXG47742.1 - 0.037 13.6 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 KXG47742.1 - 0.05 13.0 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit cNMPbd_u2 PF16643.5 KXG47742.1 - 0.56 10.7 3.3 1.2 9.6 2.8 1.7 2 0 0 2 2 2 0 Unstructured region on cNMP-binding protein DASH_Dad1 PF08649.10 KXG47743.1 - 5.7e-26 90.5 4.5 7.2e-26 90.1 4.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 KXG47743.1 - 0.024 14.6 0.4 0.034 14.1 0.4 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 V_ATPase_I PF01496.19 KXG47743.1 - 0.063 11.2 0.2 0.068 11.1 0.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF866 PF05907.13 KXG47745.1 - 4.5e-58 195.5 0.5 6.9e-58 195.0 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) LSM PF01423.22 KXG47745.1 - 5.9e-18 64.3 0.0 9.2e-18 63.7 0.0 1.3 1 0 0 1 1 1 1 LSM domain DUF4379 PF14311.6 KXG47745.1 - 4.5 7.7 6.4 0.54 10.7 0.7 2.4 2 1 1 3 3 3 0 Probable Zinc-ribbon domain HalOD2 PF18547.1 KXG47745.1 - 7.1 6.6 6.6 18 5.3 5.0 2.3 2 1 0 2 2 2 0 Halobacterial output domain 2 FAD_binding_3 PF01494.19 KXG47746.1 - 1.2e-73 248.4 0.0 1.5e-73 248.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXG47746.1 - 1.1e-37 129.6 0.1 2.1e-37 128.7 0.1 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 KXG47746.1 - 0.0011 18.6 0.1 0.015 14.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG47746.1 - 0.0015 17.8 0.0 0.026 13.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG47746.1 - 0.008 16.4 0.0 0.03 14.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXG47746.1 - 0.013 16.0 0.0 0.063 13.8 0.0 2.2 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXG47746.1 - 0.038 13.6 0.0 0.091 12.4 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KXG47746.1 - 0.097 11.7 0.0 0.23 10.5 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 KXG47746.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 KXG47746.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DDHD PF02862.17 KXG47748.1 - 4.8e-26 92.3 0.0 1.8e-15 57.7 0.0 2.9 2 1 0 3 3 3 2 DDHD domain Abhydrolase_6 PF12697.7 KXG47748.1 - 0.22 12.1 2.0 0.19 12.3 0.1 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family MoCF_biosynth PF00994.24 KXG47749.1 - 7.5e-46 155.4 0.0 6.5e-23 81.0 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KXG47749.1 - 9.9e-40 135.9 2.1 1.9e-39 135.0 2.1 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KXG47749.1 - 4.7e-14 52.3 0.2 1.2e-13 51.0 0.2 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 KXG47749.1 - 2.2 7.6 16.8 3.4 7.0 16.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ATP-synt_C PF00137.21 KXG47750.1 - 1.3e-25 89.5 26.2 2.9e-14 53.1 10.5 2.4 2 0 0 2 2 2 2 ATP synthase subunit C Oxidored_q2 PF00420.24 KXG47750.1 - 1.8 8.2 9.3 1 9.0 4.2 2.9 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L SLATT_5 PF18160.1 KXG47750.1 - 3.3 7.0 4.2 0.64 9.3 0.2 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Ras PF00071.22 KXG47751.1 - 2.7e-59 199.4 0.2 3.5e-59 199.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXG47751.1 - 4.4e-37 127.0 0.4 7.9e-37 126.1 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG47751.1 - 1.5e-17 63.6 0.1 1.8e-17 63.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXG47751.1 - 1.2e-06 28.5 0.2 0.001 19.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KXG47751.1 - 4.5e-06 26.3 0.1 2.9e-05 23.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KXG47751.1 - 5.6e-06 25.9 0.0 8.4e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KXG47751.1 - 1.4e-05 25.1 0.0 2.4e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXG47751.1 - 4.2e-05 23.0 0.2 5.4e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TIR_2 PF13676.6 KXG47751.1 - 0.086 13.5 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 TIR domain AAA_7 PF12775.7 KXG47751.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MmgE_PrpD PF03972.14 KXG47752.1 - 6.3e-130 433.6 4.2 7.2e-130 433.4 4.2 1.0 1 0 0 1 1 1 1 MmgE/PrpD family AAA_29 PF13555.6 KXG47752.1 - 0.12 12.1 1.4 0.38 10.5 0.2 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Kei1 PF08552.11 KXG47753.1 - 6.4e-67 225.1 2.8 7.7e-67 224.9 2.8 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 NIR_SIR PF01077.22 KXG47754.1 - 4.3e-51 172.6 0.0 2e-44 150.9 0.0 2.6 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KXG47754.1 - 1.6e-27 95.1 0.0 5.5e-13 48.6 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KXG47754.1 - 7.1e-27 94.4 0.0 1.4e-26 93.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 KXG47754.1 - 1.2e-06 28.4 0.1 2.5e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Abhydrolase_3 PF07859.13 KXG47755.1 - 2.8e-26 92.7 0.0 3.8e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXG47755.1 - 5.5e-13 48.5 0.0 6.6e-12 45.0 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KXG47755.1 - 0.0071 15.8 0.0 0.033 13.7 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 KXG47755.1 - 0.15 10.9 0.2 0.27 10.1 0.0 1.4 2 0 0 2 2 2 0 Carboxylesterase family GATase PF00117.28 KXG47756.1 - 6.9e-08 32.5 0.0 9.9e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXG47756.1 - 0.035 13.8 0.0 0.5 10.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 Ank_2 PF12796.7 KXG47757.1 - 2e-59 198.1 10.4 1.1e-14 54.7 0.1 6.0 4 1 2 6 6 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG47757.1 - 2.8e-48 161.7 6.9 9.5e-06 26.1 0.1 11.5 2 2 9 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 KXG47757.1 - 2.1e-44 148.1 9.8 2.2e-06 27.8 0.0 11.7 11 0 0 11 11 11 10 Ankyrin repeat Ank_3 PF13606.6 KXG47757.1 - 2.9e-37 122.4 3.2 0.00016 21.8 0.0 12.1 12 0 0 12 12 11 10 Ankyrin repeat Ank_5 PF13857.6 KXG47757.1 - 5.7e-35 118.9 9.1 1.6e-07 31.4 0.0 8.8 2 2 8 10 10 10 9 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 KXG47757.1 - 8.7e-11 41.5 0.1 2.8e-10 39.8 0.1 1.9 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KXG47757.1 - 8e-09 35.6 0.0 1.9e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Nitro_FeMo-Co PF02579.17 KXG47757.1 - 2.3e-05 24.6 16.9 0.76 10.1 0.2 6.9 2 1 5 7 7 7 3 Dinitrogenase iron-molybdenum cofactor AAA_16 PF13191.6 KXG47757.1 - 0.00023 21.6 0.3 0.0021 18.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 KXG47757.1 - 0.034 14.6 0.0 0.27 11.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GHL15 PF14885.6 KXG47757.1 - 0.23 11.4 2.2 0.48 10.3 2.2 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 DUF3843 PF12954.7 KXG47759.1 - 0.18 10.7 0.1 0.22 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) RNA_pol PF00940.19 KXG47761.1 - 1.3e-182 607.3 0.0 1.7e-182 606.9 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KXG47761.1 - 2.7e-85 286.7 0.2 4.4e-85 286.0 0.2 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Sin_N PF04801.13 KXG47761.1 - 1.2e-26 94.0 0.2 3.5e-26 92.4 0.2 1.7 1 1 0 1 1 1 1 Sin-like protein conserved region Fungal_trans PF04082.18 KXG47762.1 - 2.3e-38 131.8 0.0 4e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG47762.1 - 2.5e-09 37.1 9.2 4.1e-09 36.4 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF92 PF01940.16 KXG47763.1 - 7e-83 277.7 10.9 9.1e-83 277.3 10.9 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Lycopene_cycl PF05834.12 KXG47763.1 - 0.097 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein SP_C-Propep PF08999.10 KXG47765.1 - 0.00071 19.3 0.3 0.00089 19.0 0.3 1.1 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide ASFV_J13L PF05568.11 KXG47765.1 - 0.0012 18.7 0.2 0.0013 18.6 0.2 1.1 1 0 0 1 1 1 1 African swine fever virus J13L protein Vpu PF00558.19 KXG47765.1 - 0.003 17.3 1.2 0.0039 16.9 1.2 1.1 1 0 0 1 1 1 1 Vpu protein MscL PF01741.18 KXG47765.1 - 0.0037 17.5 0.1 0.0043 17.3 0.1 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL TMEM154 PF15102.6 KXG47765.1 - 0.0059 16.5 3.2 0.0068 16.3 3.2 1.1 1 0 0 1 1 1 1 TMEM154 protein family FeoB_associated PF12669.7 KXG47765.1 - 0.01 16.2 2.7 0.014 15.8 2.7 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Sigma_reg_N PF13800.6 KXG47765.1 - 0.017 15.4 0.1 0.021 15.1 0.1 1.1 1 0 0 1 1 1 0 Sigma factor regulator N-terminal EphA2_TM PF14575.6 KXG47765.1 - 0.03 15.2 0.0 0.031 15.1 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5385 PF17359.2 KXG47765.1 - 0.06 12.9 2.1 0.077 12.6 2.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF2207 PF09972.9 KXG47765.1 - 0.12 11.1 0.5 0.14 10.9 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3328 PF11807.8 KXG47765.1 - 0.2 11.4 0.0 0.21 11.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) RIFIN PF02009.16 KXG47765.1 - 8.9 6.1 7.0 11 5.9 7.0 1.0 1 0 0 1 1 1 0 Rifin Na_Ca_ex PF01699.24 KXG47766.1 - 2.4e-35 121.7 35.8 2e-18 66.8 11.8 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 KXG47767.1 - 1.7e-10 41.0 16.9 1.7e-10 41.0 16.9 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 KXG47768.1 - 3.6e-22 78.9 42.3 2.2e-12 47.2 16.0 2.3 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF1240 PF06836.12 KXG47768.1 - 0.051 14.1 1.7 0.051 14.1 1.7 3.1 3 1 0 4 4 4 0 Protein of unknown function (DUF1240) TPR_10 PF13374.6 KXG47769.1 - 5.5e-80 261.3 3.5 6.6e-11 41.7 0.0 9.2 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 KXG47769.1 - 6.9e-59 196.1 7.0 1.2e-12 48.0 0.1 6.7 3 2 2 6 6 6 6 Tetratricopeptide repeat Cation_ATPase_C PF00689.21 KXG47769.1 - 1.7e-44 151.7 8.7 1.7e-44 151.7 8.7 5.1 4 1 1 5 5 4 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXG47769.1 - 6e-37 126.9 0.4 6e-37 126.9 0.4 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXG47769.1 - 1.5e-18 66.7 0.0 3.3e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXG47769.1 - 2e-17 64.2 0.0 8.9e-17 62.1 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase TPR_7 PF13176.6 KXG47769.1 - 6.1e-14 50.9 10.5 0.069 13.2 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KXG47769.1 - 1.1e-13 51.3 13.2 3.4e-08 33.2 1.3 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_4 PF07721.14 KXG47769.1 - 2.1e-11 43.3 3.4 0.028 15.0 0.6 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXG47769.1 - 2.1e-09 36.8 2.6 1.8 9.0 0.1 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXG47769.1 - 4e-09 35.9 7.1 0.7 10.2 0.1 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXG47769.1 - 4.9e-09 35.6 1.9 0.77 9.7 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat Cation_ATPase_N PF00690.26 KXG47769.1 - 3.9e-07 29.7 1.1 1.2e-06 28.1 0.0 2.5 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus TPR_16 PF13432.6 KXG47769.1 - 2.9e-05 24.6 8.9 1.3 9.7 0.4 5.5 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXG47769.1 - 0.00089 19.5 13.2 13 6.4 0.1 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXG47769.1 - 0.0016 19.1 10.1 4.6 8.3 0.1 6.5 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXG47769.1 - 0.0054 17.3 5.2 13 6.6 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXG47769.1 - 0.0073 16.8 11.8 21 5.7 0.2 6.6 5 2 3 8 8 7 0 Tetratricopeptide repeat DevR PF01905.16 KXG47769.1 - 0.04 13.0 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 Hydrolase_3 PF08282.12 KXG47769.1 - 0.076 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PHO4 PF01384.20 KXG47770.1 - 3.3e-103 345.3 17.2 3.8e-103 345.1 17.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family Peptidase_M56 PF05569.11 KXG47770.1 - 0.33 10.1 1.7 0.76 8.9 1.7 1.6 1 0 0 1 1 1 0 BlaR1 peptidase M56 UPF0444 PF15475.6 KXG47770.1 - 0.69 10.2 8.9 1 9.7 0.8 3.0 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 Methyltransf_33 PF10017.9 KXG47772.1 - 7.1e-82 275.0 0.0 1e-81 274.5 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KXG47772.1 - 3.9e-20 72.5 0.6 6.3e-20 71.8 0.6 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KXG47772.1 - 1.4e-06 28.9 1.1 3.1e-06 27.7 1.1 1.7 1 0 0 1 1 1 1 DinB superfamily Aldedh PF00171.22 KXG47773.1 - 2.8e-132 441.5 0.1 3.2e-132 441.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXG47773.1 - 1.6e-05 24.2 0.0 2.8e-05 23.4 0.0 1.4 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) ATP-synt_D PF01813.17 KXG47773.1 - 0.0072 16.2 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 ATP synthase subunit D YfdX PF10938.8 KXG47773.1 - 0.19 11.7 2.1 0.32 10.9 0.2 2.1 2 0 0 2 2 2 0 YfdX protein DnaB_bind PF10410.9 KXG47773.1 - 0.62 10.3 2.1 0.97 9.7 0.2 2.3 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase LigT_PEase PF02834.16 KXG47774.1 - 0.0089 16.2 0.0 0.11 12.7 0.0 2.3 2 0 0 2 2 2 1 LigT like Phosphoesterase NB-ARC PF00931.22 KXG47775.1 - 5.1e-17 61.9 0.0 8.6e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.6 KXG47775.1 - 2.4e-16 59.8 9.7 2e-07 31.2 1.0 5.0 3 1 1 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXG47775.1 - 9.8e-09 34.8 8.6 0.015 15.2 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXG47775.1 - 2.2e-06 27.4 5.6 0.34 11.2 0.0 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXG47775.1 - 2.7e-06 27.1 12.4 0.21 11.8 0.2 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXG47775.1 - 4.1e-06 26.4 1.5 0.13 12.1 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXG47775.1 - 6e-06 26.7 7.2 0.031 14.8 0.5 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat Goodbye PF17109.5 KXG47775.1 - 9.4e-05 22.9 0.0 0.001 19.5 0.0 2.7 3 0 0 3 3 3 1 fungal STAND N-terminal Goodbye domain AAA_16 PF13191.6 KXG47775.1 - 0.0015 19.0 0.0 0.013 15.9 0.0 2.8 1 1 0 1 1 1 1 AAA ATPase domain TPR_MalT PF17874.1 KXG47775.1 - 0.0026 17.2 7.8 0.048 13.0 2.3 2.3 1 1 0 2 2 2 2 MalT-like TPR region AAA_22 PF13401.6 KXG47775.1 - 0.004 17.4 0.0 0.014 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KXG47775.1 - 0.014 14.9 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein TPR_16 PF13432.6 KXG47775.1 - 0.022 15.4 12.5 0.21 12.2 2.1 4.7 3 2 1 4 4 3 0 Tetratricopeptide repeat SNAP PF14938.6 KXG47775.1 - 0.058 12.8 2.7 0.049 13.0 0.7 1.8 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP ATPase_2 PF01637.18 KXG47775.1 - 0.068 13.1 0.1 0.29 11.0 0.1 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ANAPC3 PF12895.7 KXG47775.1 - 0.13 12.4 5.1 2.4 8.5 1.7 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF5113 PF17140.4 KXG47775.1 - 0.14 11.9 0.3 0.37 10.6 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) DUF5099 PF17025.5 KXG47775.1 - 0.17 12.3 0.0 0.69 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5099) TPR_7 PF13176.6 KXG47775.1 - 0.26 11.4 4.1 3 8.1 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXG47775.1 - 0.55 11.0 4.4 2.4e+02 2.7 0.1 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXG47775.1 - 1 10.4 15.5 11 7.2 0.5 5.8 5 2 2 7 7 5 0 Tetratricopeptide repeat TFIIA_gamma_C PF02751.14 KXG47777.1 - 7.2e-25 86.9 2.7 1.3e-24 86.1 2.7 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KXG47777.1 - 2.4e-22 78.7 0.1 3.9e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Hexokinase_1 PF00349.21 KXG47778.1 - 6.5e-61 205.7 0.0 8.9e-61 205.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KXG47778.1 - 3e-47 161.1 0.0 5.9e-46 156.8 0.0 2.2 1 1 0 1 1 1 1 Hexokinase GILT PF03227.16 KXG47779.1 - 9.7e-12 45.1 1.0 9.7e-12 45.1 1.0 2.5 2 1 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) C5-epim_C PF06662.13 KXG47780.1 - 0.022 14.2 0.1 0.098 12.1 0.1 1.9 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus ABC_tran_Xtn PF12848.7 KXG47780.1 - 0.082 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter MFS_1 PF07690.16 KXG47781.1 - 2.6e-35 122.0 23.9 2.6e-35 122.0 23.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 KXG47781.1 - 1.3e-05 24.6 0.0 1.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG47781.1 - 0.00042 19.7 0.0 0.22 10.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG47781.1 - 0.15 12.0 0.0 25 4.8 0.2 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding TPR_2 PF07719.17 KXG47782.1 - 3.1e-10 39.4 8.9 0.00039 20.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXG47782.1 - 2e-09 36.9 6.0 0.0014 18.4 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXG47782.1 - 1.3e-05 24.8 3.4 0.019 14.6 0.1 4.4 5 0 0 5 5 5 2 TPR repeat TPR_19 PF14559.6 KXG47782.1 - 0.0015 19.0 0.2 0.47 11.0 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXG47782.1 - 0.0059 16.9 7.4 0.24 11.7 1.4 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXG47782.1 - 0.011 16.4 4.9 26 5.6 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXG47782.1 - 0.021 15.0 4.6 0.99 9.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXG47782.1 - 0.026 14.5 2.8 15 5.9 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXG47782.1 - 0.047 14.5 7.5 37 5.5 0.0 4.9 4 1 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG47782.1 - 0.052 13.8 4.0 0.41 10.9 0.3 3.5 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KXG47782.1 - 0.84 10.5 5.7 2.9 8.8 1.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KXG47782.1 - 2.7 7.3 5.5 0.96 8.8 0.5 2.4 3 1 1 4 4 4 0 MalT-like TPR region Zn_clus PF00172.18 KXG47783.1 - 6e-08 32.7 9.0 1e-07 31.9 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXG47783.1 - 2.5e-06 26.7 0.7 3.7e-06 26.2 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXG47784.1 - 6.5e-33 114.1 47.9 3.6e-20 72.2 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXG47784.1 - 1.1e-07 30.8 31.1 2.7e-06 26.2 9.0 2.8 1 1 2 3 3 3 2 MFS/sugar transport protein TPR_2 PF07719.17 KXG47785.1 - 2.4e-07 30.3 5.0 0.17 12.1 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXG47785.1 - 6.5e-05 22.6 2.8 0.16 11.8 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXG47785.1 - 0.00014 21.5 6.7 1.4 8.6 0.1 5.7 7 0 0 7 7 7 2 TPR repeat TPR_16 PF13432.6 KXG47785.1 - 0.00081 20.0 7.7 1.1 9.9 0.1 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 KXG47785.1 - 0.0027 18.2 2.7 13 6.8 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXG47785.1 - 0.0071 16.6 3.1 0.21 11.9 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXG47785.1 - 0.024 15.1 0.0 0.024 15.1 0.0 4.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXG47785.1 - 0.18 12.2 1.6 1.7e+02 2.9 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXG47785.1 - 9.6 7.3 13.2 7 7.8 0.1 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat FAD_binding_4 PF01565.23 KXG47786.1 - 9.8e-18 64.2 0.1 1.8e-17 63.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG47786.1 - 1e-06 28.7 0.3 2.7e-06 27.4 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like DEAD PF00270.29 KXG47788.1 - 1.2e-17 64.2 0.0 2.9e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXG47788.1 - 1.9e-11 44.2 0.0 6e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXG47788.1 - 5.3e-06 26.8 0.6 2.5e-05 24.6 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain PhoH PF02562.16 KXG47788.1 - 0.086 12.3 0.0 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein HD PF01966.22 KXG47789.1 - 0.00011 22.4 0.7 0.00011 22.4 0.7 1.7 2 0 0 2 2 2 1 HD domain adh_short_C2 PF13561.6 KXG47790.1 - 5.4e-55 186.5 0.2 6.7e-55 186.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG47790.1 - 8.3e-47 159.2 0.1 9.8e-47 158.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG47790.1 - 1.3e-14 54.5 0.3 1.7e-14 54.1 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXG47790.1 - 4e-05 23.2 0.1 5.5e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HATPase_c PF02518.26 KXG47790.1 - 0.027 15.0 0.0 0.047 14.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NAD_binding_2 PF03446.15 KXG47790.1 - 0.037 14.2 0.0 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GDP_Man_Dehyd PF16363.5 KXG47790.1 - 0.14 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase GCP_N_terminal PF17681.1 KXG47791.1 - 4.6e-34 118.4 0.0 7.4e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXG47791.1 - 3.9e-20 72.5 0.0 7.5e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal ThiF PF00899.21 KXG47792.1 - 8.9e-109 362.5 0.0 9.6e-73 244.5 0.0 2.3 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KXG47792.1 - 3.8e-96 321.9 0.6 1e-95 320.4 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KXG47792.1 - 1.6e-30 105.6 0.0 3.4e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 KXG47792.1 - 1.3e-29 102.2 0.1 2.6e-29 101.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KXG47792.1 - 1.2e-26 92.7 1.3 3.4e-26 91.2 1.3 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle GST_N_2 PF13409.6 KXG47793.1 - 6.3e-24 84.1 0.0 1.7e-23 82.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXG47793.1 - 7.6e-17 61.1 0.0 1.7e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXG47793.1 - 2.8e-07 30.6 0.0 6.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXG47793.1 - 1.6e-05 25.2 0.1 0.00078 19.8 0.1 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXG47793.1 - 0.00022 21.3 0.0 0.00045 20.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXG47793.1 - 0.0072 16.9 0.0 0.012 16.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KXG47793.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain QIL1 PF15884.5 KXG47793.1 - 0.037 14.6 0.0 0.19 12.4 0.0 2.1 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 Mito_carr PF00153.27 KXG47794.1 - 1.7e-66 220.2 5.0 6.1e-22 77.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KXG47794.1 - 6.1e-22 77.8 3.0 1.2e-11 44.9 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXG47794.1 - 3e-21 73.3 6.1 4.4e-06 25.9 0.2 4.8 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KXG47794.1 - 5.4e-19 66.4 5.1 8e-05 22.3 0.1 4.8 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXG47794.1 - 1.6e-17 62.1 6.3 9.6e-05 21.7 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KXG47794.1 - 2.4e-12 46.5 1.2 1.3e-05 24.9 0.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXG47794.1 - 1.3e-07 31.9 0.0 0.0019 18.5 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KXG47794.1 - 0.066 13.1 0.1 30 4.6 0.0 3.1 3 0 0 3 3 3 0 EF hand Cyclin_N PF00134.23 KXG47795.1 - 1.7e-10 40.7 0.1 6.2e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KXG47795.1 - 0.11 12.9 0.7 0.4 11.1 0.2 2.2 2 1 0 2 2 2 0 Cyclin C-terminal domain DUF4452 PF14618.6 KXG47796.1 - 2.3e-68 229.3 9.5 3e-68 229.0 9.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Asp PF00026.23 KXG47797.1 - 9.5e-61 205.9 1.2 1.7e-60 205.1 0.8 1.6 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXG47797.1 - 1.9e-10 41.3 1.1 2.5e-05 24.6 0.4 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXG47797.1 - 5.6e-06 26.9 0.5 0.0037 17.9 0.2 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KXG47797.1 - 0.0023 17.7 0.0 0.018 14.8 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KXG47797.1 - 0.0089 16.6 0.0 0.25 11.9 0.0 2.9 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease tRNA_bind PF01588.20 KXG47798.1 - 7.6e-22 77.2 0.0 6.2e-21 74.3 0.0 2.2 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 KXG47798.1 - 5e-05 23.3 0.0 9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXG47798.1 - 0.011 16.0 0.0 0.011 16.0 0.0 2.2 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KXG47798.1 - 0.064 13.1 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ferlin_C PF16165.5 KXG47798.1 - 2.2 8.2 5.2 3.7 7.5 5.2 1.2 1 0 0 1 1 1 0 Ferlin C-terminus Ank_2 PF12796.7 KXG47799.1 - 2.7e-29 101.6 1.3 1.7e-08 34.9 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG47799.1 - 3.8e-25 87.9 1.5 1.5e-06 28.6 0.1 6.1 4 3 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG47799.1 - 6.8e-19 67.7 2.0 2.5e-07 30.9 0.1 5.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KXG47799.1 - 1.8e-18 66.1 2.0 0.00046 20.5 0.2 7.8 8 1 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.6 KXG47799.1 - 3e-16 57.9 2.6 0.0016 18.7 0.0 7.9 9 0 0 9 9 9 3 Ankyrin repeat bZIP_1 PF00170.21 KXG47800.1 - 6e-06 26.3 6.0 8.4e-06 25.8 6.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXG47800.1 - 7.4e-05 22.8 7.4 0.0001 22.3 7.4 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXG47800.1 - 0.00022 21.7 5.5 0.00035 21.0 5.5 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor CASP_C PF08172.12 KXG47800.1 - 0.031 13.6 1.1 0.04 13.2 1.1 1.1 1 0 0 1 1 1 0 CASP C terminal ADH_N PF08240.12 KXG47801.1 - 7.4e-24 83.7 0.1 1.6e-23 82.6 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG47801.1 - 1.5e-23 83.2 2.3 2.3e-23 82.6 2.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXG47801.1 - 5.3e-07 29.3 3.6 7.3e-07 28.9 3.6 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 KXG47801.1 - 0.00018 21.4 1.8 0.00064 19.6 0.0 2.8 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-associated Shikimate_DH PF01488.20 KXG47801.1 - 0.0059 16.7 0.6 0.016 15.3 0.1 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KXG47801.1 - 0.035 13.5 0.1 0.086 12.2 0.1 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KXG47801.1 - 0.12 12.9 1.2 1.8 9.1 1.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXG47801.1 - 0.29 10.3 2.0 0.35 10.0 1.5 1.5 1 1 1 2 2 2 0 FAD binding domain Anp1 PF03452.14 KXG47802.1 - 7.4e-113 376.3 0.0 1.1e-112 375.7 0.0 1.3 1 0 0 1 1 1 1 Anp1 KR PF08659.10 KXG47802.1 - 1e-07 32.1 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KXG47802.1 - 1.6e-07 31.0 0.0 2.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KXG47802.1 - 0.02 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG47802.1 - 0.16 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Dcc1 PF09724.9 KXG47803.1 - 1.2e-26 93.9 0.0 1.4e-26 93.6 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Acetyltransf_7 PF13508.7 KXG47804.1 - 5.1e-06 26.8 0.0 9.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG47804.1 - 0.00016 21.9 0.0 0.00044 20.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KXG47804.1 - 0.00042 20.4 0.1 0.0017 18.4 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXG47804.1 - 0.0006 19.8 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KXG47804.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase FR47 PF08445.10 KXG47804.1 - 0.02 14.9 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein HORMA PF02301.18 KXG47805.1 - 4.3e-11 42.8 0.0 5.8e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 HORMA domain IBN_N PF03810.19 KXG47806.1 - 4.9e-08 32.8 0.1 4.3e-07 29.8 0.1 2.8 1 1 0 1 1 1 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.15 KXG47806.1 - 0.00065 18.3 0.0 0.0018 16.9 0.0 1.7 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus RIX1 PF08167.12 KXG47806.1 - 0.00075 19.3 0.1 0.0088 15.8 0.0 2.9 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Xpo1 PF08389.12 KXG47806.1 - 0.00099 19.2 0.1 0.1 12.7 0.0 4.1 5 1 0 5 5 5 1 Exportin 1-like protein Cnd3 PF12719.7 KXG47806.1 - 0.0057 15.9 0.1 0.036 13.3 0.1 2.4 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Proteasom_PSMB PF10508.9 KXG47806.1 - 0.028 13.0 0.0 2.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Methyltransf_23 PF13489.6 KXG47807.1 - 4.4e-25 88.4 0.0 6.8e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG47807.1 - 3.6e-13 50.0 0.0 9.6e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG47807.1 - 1.1e-11 44.7 0.0 7.7e-11 42.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG47807.1 - 5e-11 43.2 0.0 1.8e-10 41.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG47807.1 - 1.9e-10 41.2 0.0 4.4e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXG47807.1 - 2.5e-05 23.8 0.0 0.00033 20.2 0.0 2.3 2 1 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 KXG47807.1 - 0.0015 17.9 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KXG47807.1 - 0.0023 18.1 0.0 0.0056 16.8 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase CMAS PF02353.20 KXG47807.1 - 0.011 15.0 0.0 0.028 13.7 0.0 1.7 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KXG47807.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase MTS PF05175.14 KXG47807.1 - 0.021 14.4 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain DUF4377 PF14302.6 KXG47807.1 - 0.15 12.1 0.1 31 4.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4377) DUF938 PF06080.12 KXG47807.1 - 0.17 11.6 0.0 0.45 10.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Zn_clus PF00172.18 KXG47808.1 - 8e-09 35.5 6.4 1.3e-08 34.8 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myc-LZ PF02344.15 KXG47808.1 - 0.065 13.3 0.4 1.1 9.4 0.1 2.2 2 0 0 2 2 2 0 Myc leucine zipper domain TolA_bind_tri PF16331.5 KXG47808.1 - 0.14 12.3 4.4 0.23 11.5 4.4 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation SlyX PF04102.12 KXG47808.1 - 0.33 11.6 3.2 0.67 10.6 3.2 1.4 1 0 0 1 1 1 0 SlyX Melibiase_2 PF16499.5 KXG47809.1 - 1.1e-64 218.3 0.8 1.6e-64 217.8 0.8 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KXG47809.1 - 5.5e-11 42.4 0.3 4.7e-10 39.4 0.0 2.7 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KXG47809.1 - 1.5e-05 24.1 0.4 3.8e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Melibiase DUF4751 PF15942.5 KXG47809.1 - 0.059 13.3 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4751) PhyH PF05721.13 KXG47810.1 - 9.6e-10 39.1 0.4 2.4e-09 37.8 0.4 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Het-C PF07217.11 KXG47811.1 - 8.6e-276 915.9 0.0 1.2e-275 915.4 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Fungal_trans PF04082.18 KXG47814.1 - 5.5e-09 35.4 0.1 9.2e-09 34.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-TRAF PF02176.18 KXG47815.1 - 3.8e-11 43.5 21.0 4.6e-08 33.6 3.2 4.1 1 1 3 4 4 4 4 TRAF-type zinc finger zf-RING_UBOX PF13445.6 KXG47815.1 - 3.4e-07 30.2 10.8 1.4e-06 28.2 10.8 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-TRAF_2 PF15965.5 KXG47815.1 - 4.7e-07 30.2 10.2 4.7e-07 30.2 10.2 3.1 1 1 0 2 2 2 2 TRAF-like zinc-finger zf-C3HC4_4 PF15227.6 KXG47815.1 - 4.4e-06 26.7 13.3 4.4e-06 26.7 13.3 2.7 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KXG47815.1 - 6.9e-06 25.8 10.6 6.9e-06 25.8 10.6 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXG47815.1 - 8.3e-06 26.1 11.8 8.3e-06 26.1 11.8 3.7 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 KXG47815.1 - 0.00018 21.4 10.2 0.00018 21.4 10.2 3.2 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXG47815.1 - 0.00058 19.7 9.1 0.00058 19.7 9.1 3.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) TSC22 PF01166.18 KXG47815.1 - 0.21 11.9 1.0 5.2 7.5 0.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family SNARE PF05739.19 KXG47816.1 - 2.1e-08 34.0 1.1 3.8e-08 33.2 1.1 1.5 1 0 0 1 1 1 1 SNARE domain DUF4407 PF14362.6 KXG47816.1 - 0.011 15.1 0.6 0.049 13.0 0.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Snapin_Pallidin PF14712.6 KXG47816.1 - 0.022 15.2 1.0 0.85 10.1 0.1 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Use1 PF09753.9 KXG47816.1 - 0.039 13.7 0.3 0.14 11.9 0.3 2.0 1 1 0 1 1 1 0 Membrane fusion protein Use1 ABC_tran_CTD PF16326.5 KXG47816.1 - 0.045 14.0 1.9 0.078 13.2 0.4 2.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain HrpB7 PF09486.10 KXG47816.1 - 0.46 10.8 7.6 0.14 12.6 0.8 2.5 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) EspB_PE PF18625.1 KXG47816.1 - 0.59 10.6 4.2 0.32 11.5 0.9 2.3 2 1 1 3 3 3 0 ESX-1 secreted protein B PE domain XhlA PF10779.9 KXG47816.1 - 1.2 9.4 9.5 3.3 8.0 6.6 2.8 2 1 0 2 2 2 0 Haemolysin XhlA Jacalin PF01419.17 KXG47818.1 - 0.002 18.0 0.2 0.0048 16.8 0.2 1.7 1 1 0 1 1 1 1 Jacalin-like lectin domain Mo-co_dimer PF03404.16 KXG47818.1 - 0.049 13.6 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain ParA PF10609.9 KXG47819.1 - 5.1e-97 324.2 0.0 5.9e-97 323.9 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXG47819.1 - 9.1e-09 35.5 0.0 1.9e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KXG47819.1 - 1e-05 24.9 1.4 0.00024 20.4 0.3 2.6 1 1 1 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.6 KXG47819.1 - 1.3e-05 25.2 0.1 0.00013 21.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KXG47819.1 - 0.0019 18.1 0.1 0.5 10.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 KXG47819.1 - 0.017 14.5 0.0 0.039 13.2 0.0 1.6 1 1 0 1 1 1 0 ATPase MipZ RsgA_GTPase PF03193.16 KXG47819.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 KXG47819.1 - 0.034 13.9 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KXG47819.1 - 0.036 13.9 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 KXG47819.1 - 0.045 13.3 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 KXG47819.1 - 0.099 12.1 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 KXG47819.1 - 0.14 12.5 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KXG47819.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KXG47819.1 - 0.19 11.7 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KXG47819.1 - 0.22 10.7 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Kinesin PF00225.23 KXG47820.1 - 1.1e-57 195.5 0.1 8.6e-31 107.1 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KXG47820.1 - 5.5e-11 42.6 0.0 1.2e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding PEMT PF04191.13 KXG47821.1 - 1.5e-59 198.9 8.7 1.9e-36 124.7 1.5 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase SKICH PF17751.1 KXG47821.1 - 0.0041 17.7 0.1 0.055 14.0 0.1 2.3 1 1 0 1 1 1 1 SKICH domain HECW_N PF16562.5 KXG47821.1 - 0.0056 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 RNase_PH PF01138.21 KXG47822.1 - 1.8e-31 109.4 0.1 3.4e-31 108.5 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 ProRS-C_1 PF09180.11 KXG47824.1 - 2.1e-22 79.1 2.5 5.4e-22 77.8 2.5 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KXG47824.1 - 1.1e-18 67.8 0.0 1.8e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXG47824.1 - 8e-11 42.0 0.0 3.6e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain Cpn60_TCP1 PF00118.24 KXG47825.1 - 1.3e-149 499.0 18.3 1.5e-149 498.8 18.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pex14_N PF04695.13 KXG47826.1 - 6.7 7.3 15.2 0.099 13.3 5.5 2.5 1 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UCMA PF17085.5 KXG47826.1 - 7.1 6.7 18.0 1.7 8.6 13.9 2.1 2 0 0 2 2 2 0 Unique cartilage matrix associated protein WD40 PF00400.32 KXG47827.1 - 8.4e-17 61.2 3.0 0.00013 22.7 0.1 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG47827.1 - 9.3e-08 32.3 0.0 0.016 15.5 0.0 4.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Met_asp_mut_E PF06368.11 KXG47827.1 - 0.16 10.4 0.0 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) ORC6 PF05460.13 KXG47827.1 - 1.3 8.2 5.3 2.1 7.6 5.3 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MFS_1 PF07690.16 KXG47828.1 - 3.5e-31 108.4 4.7 4.3e-31 108.1 4.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG47828.1 - 7.9e-06 25.0 8.5 1.8e-05 23.8 8.5 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KXG47828.1 - 0.018 13.3 2.0 0.023 13.0 0.4 1.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MFS_5 PF05631.14 KXG47828.1 - 0.04 12.8 0.1 0.063 12.2 0.1 1.4 1 1 0 1 1 1 0 Sugar-tranasporters, 12 TM S1 PF00575.23 KXG47829.1 - 1e-70 234.0 24.5 4.8e-15 55.7 1.8 12.0 12 0 0 12 12 12 9 S1 RNA binding domain Suf PF05843.14 KXG47829.1 - 1.9e-08 34.6 12.7 0.0086 16.1 0.0 5.3 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KXG47829.1 - 9.8e-07 29.2 0.1 0.021 15.3 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXG47829.1 - 1.1e-05 25.9 3.1 1.1 10.2 0.5 5.9 4 2 3 7 7 6 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 KXG47829.1 - 0.00061 19.7 0.0 20 5.2 0.0 5.3 5 0 0 5 5 5 0 RNase II-type exonuclease C-terminal S1 domain PPR PF01535.20 KXG47829.1 - 0.0033 17.6 0.2 9.7 6.7 0.0 3.7 3 0 0 3 3 3 2 PPR repeat TPR_15 PF13429.6 KXG47829.1 - 0.0042 16.3 1.8 0.48 9.6 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KXG47829.1 - 0.0092 16.0 0.2 0.017 15.1 0.2 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 TPR_16 PF13432.6 KXG47829.1 - 0.01 16.5 0.2 28 5.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat S1_2 PF13509.6 KXG47829.1 - 0.017 15.2 0.2 6 7.0 0.0 4.0 4 0 0 4 4 4 0 S1 domain PPR_2 PF13041.6 KXG47829.1 - 0.018 15.2 0.0 36 4.7 0.0 3.5 3 0 0 3 3 3 0 PPR repeat family LID PF17916.1 KXG47831.1 - 0.11 12.1 1.1 0.26 11.0 1.1 1.6 1 0 0 1 1 1 0 LIM interaction domain (LID) DUF726 PF05277.12 KXG47831.1 - 1.1 8.2 6.2 1.6 7.6 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) UreD PF01774.17 KXG47832.1 - 3.2e-77 259.3 0.0 4.6e-77 258.7 0.0 1.2 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.11 KXG47833.1 - 8.7e-40 135.2 6.5 2.9e-39 133.5 2.6 3.1 2 0 0 2 2 2 1 STAG domain Nipped-B_C PF12830.7 KXG47833.1 - 0.019 14.9 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus MIF4G PF02854.19 KXG47833.1 - 0.047 13.3 0.0 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 MIF4G domain HEAT_2 PF13646.6 KXG47833.1 - 0.62 10.5 3.9 0.48 10.9 0.2 2.9 4 0 0 4 4 4 0 HEAT repeats BLOC1_2 PF10046.9 KXG47833.1 - 2.4 8.5 8.1 0.34 11.2 0.6 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Arm PF00514.23 KXG47834.1 - 1e-91 298.5 13.5 4.1e-14 52.0 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KXG47834.1 - 5.2e-27 94.1 4.9 1.3e-26 92.9 4.9 1.7 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KXG47834.1 - 8.7e-24 82.8 3.7 1.9e-23 81.8 3.7 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 KXG47834.1 - 6.5e-20 71.2 6.7 1.3e-08 35.2 0.0 6.3 5 2 2 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 KXG47834.1 - 7.2e-18 64.8 0.1 6.8e-08 32.8 0.0 5.0 1 1 3 5 5 5 3 HEAT repeats HEAT PF02985.22 KXG47834.1 - 3.8e-16 57.8 0.7 3.5e-06 26.8 0.0 7.0 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.13 KXG47834.1 - 1.7e-08 34.2 0.0 0.0022 17.5 0.0 3.9 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.8 KXG47834.1 - 7.9e-05 22.8 0.0 1.5 9.0 0.0 4.6 4 1 0 4 4 4 1 V-ATPase subunit H HEAT_PBS PF03130.16 KXG47834.1 - 0.026 15.2 1.2 1.5 9.8 0.0 4.1 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Gcn1_N PF12074.8 KXG47834.1 - 0.058 12.7 0.0 8.7 5.5 0.0 2.3 2 0 0 2 2 2 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal RICTOR_V PF14668.6 KXG47834.1 - 0.11 12.7 3.8 1.5 9.1 0.0 4.3 4 2 1 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 POT1PC PF16686.5 KXG47835.1 - 5.2e-37 127.1 0.2 3.2e-35 121.3 0.1 2.4 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KXG47835.1 - 1e-20 74.1 0.1 2.6e-20 72.7 0.0 1.8 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.25 KXG47835.1 - 0.0031 17.5 0.0 0.8 9.7 0.0 2.5 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain zf-CCCH_2 PF14608.6 KXG47836.1 - 0.08 13.4 0.2 0.08 13.4 0.2 3.1 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger TRAP_alpha PF03896.16 KXG47837.1 - 1.4e-14 54.0 0.0 2.1e-14 53.4 0.0 1.3 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit PepSY_TM PF03929.16 KXG47837.1 - 0.11 12.2 0.0 4.3 6.9 0.0 2.0 2 0 0 2 2 2 0 PepSY-associated TM region zf-C2HE PF16278.5 KXG47838.1 - 2.5e-20 72.7 0.1 5.7e-20 71.5 0.1 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 KXG47838.1 - 4.4e-17 62.6 1.6 1.2e-16 61.2 1.6 1.7 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXG47838.1 - 8.6e-17 61.7 5.2 7.5e-16 58.6 5.2 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HA2 PF04408.23 KXG47839.1 - 1.2e-18 67.4 0.4 3.9e-17 62.5 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXG47839.1 - 7.4e-16 58.3 0.0 1.7e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.22 KXG47839.1 - 8.1e-14 51.9 0.0 2.2e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 RWD domain Helicase_C PF00271.31 KXG47839.1 - 1.6e-13 51.0 0.0 3.4e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXG47839.1 - 8.3e-10 38.7 0.0 1.6e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 KXG47839.1 - 0.0046 16.4 0.0 0.0081 15.6 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein T2SSE PF00437.20 KXG47839.1 - 0.0077 15.3 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 KXG47839.1 - 0.0099 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KXG47839.1 - 0.011 16.0 2.9 0.28 11.5 2.9 2.4 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KXG47839.1 - 0.019 14.4 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 KaiC DND1_DSRM PF14709.7 KXG47839.1 - 0.038 14.2 0.1 0.12 12.7 0.1 1.9 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 dsRBD2 PF17842.1 KXG47839.1 - 0.058 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 ResIII PF04851.15 KXG47839.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 KXG47839.1 - 0.23 11.9 0.1 0.23 11.9 0.1 1.8 2 0 0 2 2 1 0 AAA domain Cyclin_N PF00134.23 KXG47840.1 - 1.7e-43 147.4 0.2 3.9e-43 146.2 0.2 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXG47840.1 - 2.2e-32 111.6 0.0 5.8e-32 110.3 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF433 PF04255.14 KXG47840.1 - 0.14 12.1 0.5 0.89 9.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF433) Zn_clus PF00172.18 KXG47841.1 - 0.0032 17.5 12.7 0.006 16.7 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 KXG47841.1 - 0.093 12.2 0.1 0.33 10.5 0.1 2.0 1 0 0 1 1 1 0 Histone chaperone domain CHZ RNA_pol_Rpc4 PF05132.14 KXG47842.1 - 1.4e-33 116.4 0.1 1.4e-33 116.4 0.1 3.9 2 2 1 3 3 3 1 RNA polymerase III RPC4 CRCB PF02537.15 KXG47845.1 - 2.5e-38 130.3 16.1 7.9e-22 77.4 7.2 2.6 2 1 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) UPRTase PF14681.6 KXG47846.1 - 1.9e-70 236.5 0.0 2.9e-69 232.7 0.0 1.9 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KXG47846.1 - 8.4e-06 25.4 0.0 7.2e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GNVR PF13807.6 KXG47846.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase Fungal_trans PF04082.18 KXG47847.1 - 1.2e-18 67.1 2.0 1.9e-18 66.4 2.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KXG47847.1 - 8.8e-07 29.1 14.9 7.4e-05 23.0 5.5 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXG47847.1 - 0.00092 19.5 14.3 0.038 14.5 5.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXG47847.1 - 0.002 18.8 12.6 0.26 12.2 4.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KXG47847.1 - 0.018 15.7 0.3 0.37 11.5 0.1 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF3361 PF11841.8 KXG47847.1 - 0.08 12.9 0.1 10 6.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) zf-C2H2_jaz PF12171.8 KXG47847.1 - 0.94 9.8 6.1 1.3 9.4 3.7 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KXG47847.1 - 1.5 9.0 3.7 5.7 7.2 3.7 2.0 1 0 0 1 1 1 0 Zinc ribbon domain RasGEF PF00617.19 KXG47848.1 - 5.1e-59 199.4 0.0 9.4e-59 198.6 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXG47848.1 - 4.4e-30 104.0 0.6 9e-30 103.0 0.6 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KXG47848.1 - 1.4e-14 53.4 0.2 1.4e-14 53.4 0.2 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXG47848.1 - 5.3e-13 48.6 0.1 1.4e-12 47.2 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXG47848.1 - 1.6e-10 40.5 0.1 4.8e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.26 KXG47848.1 - 0.0069 16.4 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 WW domain JAB PF01398.21 KXG47849.1 - 3.5e-30 104.4 0.0 6.7e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KXG47849.1 - 1.6e-18 67.4 0.0 3.7e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KXG47849.1 - 0.00029 20.6 0.0 0.00048 19.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MAP65_ASE1 PF03999.12 KXG47850.1 - 1.6e-71 241.8 13.3 2.8e-71 241.0 13.3 1.3 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) LTXXQ PF07813.12 KXG47850.1 - 0.52 11.1 6.8 0.45 11.2 0.3 3.4 3 0 0 3 3 3 0 LTXXQ motif family protein Occludin_ELL PF07303.13 KXG47850.1 - 2.4 8.9 4.4 3.2 8.5 0.1 3.2 2 2 0 2 2 2 0 Occludin homology domain ABC_tran PF00005.27 KXG47851.1 - 2e-48 164.4 0.0 6e-29 101.3 0.1 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXG47851.1 - 1e-29 104.1 29.4 1.7e-22 80.4 8.8 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KXG47851.1 - 1.6e-09 37.5 1.8 0.00016 21.2 0.2 3.9 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXG47851.1 - 7.6e-09 35.8 0.1 0.034 14.0 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KXG47851.1 - 6.4e-06 26.7 0.0 0.19 12.3 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KXG47851.1 - 7.5e-06 25.7 0.2 0.17 11.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KXG47851.1 - 9.9e-06 25.8 0.0 0.033 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXG47851.1 - 2.3e-05 24.0 1.6 0.17 11.6 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXG47851.1 - 2.7e-05 24.5 0.1 0.32 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KXG47851.1 - 0.00023 21.2 0.3 0.54 10.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.12 KXG47851.1 - 0.0013 18.7 1.1 0.17 11.8 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_24 PF13479.6 KXG47851.1 - 0.0014 18.4 0.2 0.22 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KXG47851.1 - 0.0026 17.9 1.3 0.34 11.0 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain NB-ARC PF00931.22 KXG47851.1 - 0.0038 16.4 0.1 2.2 7.4 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain RsgA_GTPase PF03193.16 KXG47851.1 - 0.0042 17.0 0.7 3.9 7.3 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXG47851.1 - 0.0067 16.8 0.1 2.9 8.2 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KXG47851.1 - 0.0068 16.9 2.4 0.66 10.4 0.5 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KXG47851.1 - 0.0076 16.2 0.1 0.32 11.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KXG47851.1 - 0.023 14.3 0.9 2 7.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 KXG47851.1 - 0.023 14.4 1.7 5 6.8 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 KXG47851.1 - 0.04 13.4 0.1 10 5.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KXG47851.1 - 0.042 13.2 0.7 8.8 5.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 KXG47851.1 - 0.043 13.6 0.1 0.68 9.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 KXG47851.1 - 0.054 13.9 0.2 11 6.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 KXG47851.1 - 0.096 13.1 0.0 2.8 8.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KXG47851.1 - 0.12 11.4 0.8 5.7 5.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.23 KXG47851.1 - 0.12 12.4 2.5 2.5 8.1 0.2 2.4 2 0 0 2 2 2 0 Dynamin family dNK PF01712.19 KXG47851.1 - 0.24 11.3 0.7 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase CLP1_P PF16575.5 KXG47851.1 - 0.24 11.2 0.5 5.1 6.8 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 KXG47851.1 - 0.3 10.8 0.9 1.6 8.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 KXG47851.1 - 0.71 9.2 2.3 9.5 5.5 0.1 2.7 3 0 0 3 3 2 0 KaiC tRNA-synt_1c PF00749.21 KXG47852.1 - 9.6e-92 307.2 0.0 1.2e-91 306.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ_C PF01556.18 KXG47853.1 - 4.8e-36 124.1 0.2 8.2e-36 123.3 0.2 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXG47853.1 - 1.1e-15 57.4 3.0 4.3e-15 55.6 3.0 2.0 1 1 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXG47853.1 - 1.8e-13 50.6 20.3 3.1e-13 49.9 20.3 1.4 1 0 0 1 1 1 1 DnaJ central domain RseC_MucC PF04246.12 KXG47853.1 - 0.099 12.6 0.2 0.099 12.6 0.2 2.2 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF1356 PF07092.12 KXG47853.1 - 2 7.7 5.7 8.5 5.6 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) HypA PF01155.19 KXG47853.1 - 3.6 7.6 12.5 7 6.7 2.3 2.3 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 KXG47853.1 - 8.4 6.6 10.7 2.7 8.2 0.8 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 ILVD_EDD PF00920.21 KXG47854.1 - 5.2e-129 431.2 0.0 3e-125 418.8 0.0 2.0 1 1 1 2 2 2 2 Dehydratase family SHOCT PF09851.9 KXG47854.1 - 0.48 10.2 0.1 0.48 10.2 0.1 2.6 3 0 0 3 3 3 0 Short C-terminal domain Sugar_tr PF00083.24 KXG47855.1 - 9e-119 397.3 29.2 1e-118 397.1 29.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG47855.1 - 1.9e-23 82.9 50.9 3e-21 75.7 28.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Aa_trans PF01490.18 KXG47856.1 - 1.2e-33 116.4 24.4 1.9e-33 115.8 24.4 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Abhydrolase_6 PF12697.7 KXG47857.1 - 2.1e-19 71.0 0.2 2.5e-19 70.7 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG47857.1 - 3.4e-17 62.9 0.2 6.8e-17 62.0 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG47857.1 - 4.6e-09 35.9 0.0 7.4e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 KXG47857.1 - 9.9e-05 21.8 0.0 0.0057 16.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KXG47857.1 - 0.00026 20.7 0.0 0.00038 20.2 0.0 1.2 1 0 0 1 1 1 1 Putative esterase UPF0227 PF05728.12 KXG47857.1 - 0.0011 19.0 0.1 0.0019 18.1 0.1 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Palm_thioest PF02089.15 KXG47857.1 - 0.0051 16.7 0.0 0.006 16.4 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Peptidase_S9 PF00326.21 KXG47857.1 - 0.013 14.9 0.0 0.32 10.5 0.0 2.6 3 0 0 3 3 3 0 Prolyl oligopeptidase family PGAP1 PF07819.13 KXG47857.1 - 0.017 14.9 0.0 0.093 12.4 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Thioesterase PF00975.20 KXG47857.1 - 0.019 15.1 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase PF07224.11 KXG47857.1 - 0.021 13.9 0.1 0.035 13.1 0.1 1.3 1 1 0 1 1 1 0 Chlorophyllase IMS_HHH PF11798.8 KXG47857.1 - 0.078 13.3 0.0 0.48 10.9 0.0 2.2 2 0 0 2 2 2 0 IMS family HHH motif Abhydrolase_2 PF02230.16 KXG47857.1 - 0.097 12.5 0.1 2.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 KXG47857.1 - 0.17 10.8 0.1 0.41 9.5 0.1 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme Ku PF02735.16 KXG47857.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain 4HBT PF03061.22 KXG47859.1 - 3.5e-14 52.9 0.0 6.6e-14 52.0 0.0 1.5 1 1 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KXG47859.1 - 4.8e-05 23.8 0.0 7.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KXG47859.1 - 0.00049 19.5 0.2 0.00076 18.8 0.2 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase Hexapep PF00132.24 KXG47860.1 - 9.6e-10 37.8 12.2 4.1e-05 23.1 2.8 3.5 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KXG47860.1 - 6.8e-05 22.0 5.3 0.00044 19.3 5.3 2.0 1 1 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 KXG47860.1 - 0.0084 15.8 11.3 0.044 13.5 4.4 2.8 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Dicer_N PF17895.1 KXG47860.1 - 0.02 14.7 0.2 0.039 13.8 0.2 1.4 1 0 0 1 1 1 0 Giardia Dicer N-terminal domain DUF4954 PF16314.5 KXG47860.1 - 0.047 11.8 2.6 0.068 11.3 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) MFS_1 PF07690.16 KXG47861.1 - 6.7e-24 84.5 49.8 6.7e-24 84.5 49.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PseudoU_synth_2 PF00849.22 KXG47862.1 - 2.1e-26 92.9 0.0 3.4e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KXG47862.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 S4 domain Fringe PF02434.16 KXG47863.1 - 7.4e-06 25.6 3.0 8.9e-05 22.0 0.5 3.1 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.6 KXG47863.1 - 0.27 11.2 1.8 0.53 10.2 0.7 1.9 2 0 0 2 2 2 0 PAN domain Ribosomal_L32e PF01655.18 KXG47864.1 - 8.7e-50 167.7 1.0 2e-49 166.5 1.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L32 GFO_IDH_MocA PF01408.22 KXG47864.1 - 3.5e-15 56.9 0.0 8.7e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXG47864.1 - 0.0059 16.6 0.0 0.015 15.3 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Sec2p PF06428.11 KXG47865.1 - 6.5e-10 38.8 10.0 6.5e-10 38.8 10.0 1.9 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p bZIP_1 PF00170.21 KXG47865.1 - 0.00033 20.7 11.6 0.065 13.3 0.0 3.2 2 1 1 3 3 3 2 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 KXG47865.1 - 0.0013 19.0 17.7 0.64 10.2 0.0 2.1 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 ATG16 PF08614.11 KXG47865.1 - 0.004 17.4 19.6 0.01 16.1 11.9 2.4 1 1 0 2 2 2 1 Autophagy protein 16 (ATG16) FAM76 PF16046.5 KXG47865.1 - 0.013 14.9 0.3 0.017 14.5 0.3 1.2 1 0 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 KXG47865.1 - 0.022 13.6 11.5 0.47 9.3 9.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 KXG47865.1 - 0.042 13.4 9.2 0.072 12.6 6.6 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF2746 PF10874.8 KXG47865.1 - 0.047 14.1 0.1 0.11 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Fib_alpha PF08702.10 KXG47865.1 - 0.08 13.1 2.8 15 5.7 0.0 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Cluap1 PF10234.9 KXG47865.1 - 0.21 11.0 12.4 0.15 11.4 10.1 1.7 2 0 0 2 2 2 0 Clusterin-associated protein-1 Vac_Fusion PF02346.16 KXG47865.1 - 0.4 10.4 4.6 2.7 7.7 2.2 2.3 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 YabA PF06156.13 KXG47865.1 - 0.58 10.8 3.3 51 4.6 0.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA YlqD PF11068.8 KXG47865.1 - 1.2 9.5 11.3 1 9.7 8.7 1.9 2 0 0 2 2 2 0 YlqD protein SlyX PF04102.12 KXG47865.1 - 1.4 9.5 14.0 48 4.7 0.0 4.1 2 1 2 4 4 4 0 SlyX GCN5L1 PF06320.13 KXG47865.1 - 4.8 7.4 9.5 5.4 7.2 6.6 2.0 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) COG2 PF06148.11 KXG47865.1 - 7.2 6.7 9.8 37 4.4 0.0 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 RRM_1 PF00076.22 KXG47866.1 - 1e-15 57.3 1.6 1.2e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TraT PF05818.12 KXG47867.1 - 0.022 14.4 0.3 0.049 13.3 0.0 1.6 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Osmo_CC PF08946.10 KXG47867.1 - 0.025 14.8 0.4 0.051 13.8 0.4 1.4 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Fmp27 PF10344.9 KXG47868.1 - 1.6e-247 824.0 0.0 4.6e-247 822.4 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 KXG47868.1 - 1.6e-191 637.4 0.0 1.6e-191 637.4 0.0 4.1 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KXG47868.1 - 5.8e-174 579.5 2.1 5.8e-174 579.5 2.1 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 KXG47868.1 - 2.4e-55 186.9 0.7 7.1e-55 185.4 0.0 2.3 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KXG47868.1 - 1.2e-54 184.4 0.0 2.7e-54 183.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KXG47868.1 - 4.2e-29 101.3 0.0 3.8e-28 98.2 0.0 2.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Glyco_hydro_35 PF01301.19 KXG47869.1 - 3.3e-88 296.4 0.3 4.2e-88 296.0 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 KXG47869.1 - 4.2e-09 36.2 0.1 4.1e-08 33.0 0.1 2.1 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 KXG47869.1 - 0.00036 21.1 0.0 0.0084 16.7 0.0 2.7 2 1 0 2 2 2 1 Beta-galactosidase jelly roll domain Cellulase PF00150.18 KXG47869.1 - 0.0085 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NA37 PF04245.13 KXG47869.1 - 0.23 10.9 0.0 0.37 10.2 0.0 1.2 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein DUF1857 PF08982.11 KXG47870.1 - 4.1e-44 150.0 0.0 4.6e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) B-block_TFIIIC PF04182.12 KXG47872.1 - 7.8e-21 74.0 0.1 7.5e-20 70.9 0.0 2.6 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC MG3 PF17791.1 KXG47872.1 - 0.15 12.4 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 Macroglobulin domain MG3 MarR_2 PF12802.7 KXG47872.1 - 0.29 11.1 2.1 2.4 8.1 0.0 3.1 3 0 0 3 3 3 0 MarR family Aldedh PF00171.22 KXG47873.1 - 2e-120 402.5 1.7 2.1e-119 399.1 1.1 1.9 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF1344 PF07076.11 KXG47873.1 - 0.11 12.5 0.0 8.9 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) LuxC PF05893.14 KXG47873.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) NAD_binding_1 PF00175.21 KXG47874.1 - 4.3e-11 43.4 0.0 1.2e-10 42.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KXG47874.1 - 5.3e-10 39.8 0.0 1.3e-09 38.5 0.0 1.7 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.12 KXG47874.1 - 3.8e-07 30.4 0.0 3.8e-06 27.1 0.0 2.6 2 1 1 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 KXG47874.1 - 9.9e-05 22.6 0.0 0.00022 21.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NMO PF03060.15 KXG47875.1 - 2e-31 109.6 3.4 5.7e-21 75.3 0.8 2.7 2 1 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KXG47875.1 - 1.2e-06 27.8 5.1 5.5e-05 22.3 3.6 2.6 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXG47875.1 - 2.4e-06 26.8 2.8 3e-06 26.5 0.8 2.0 3 0 0 3 3 3 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXG47875.1 - 0.00099 18.3 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Aminotran_1_2 PF00155.21 KXG47877.1 - 5.3e-46 157.5 0.0 6.4e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Tyrosinase PF00264.20 KXG47878.1 - 4.9e-50 170.9 3.5 8.6e-50 170.1 3.5 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KXG47878.1 - 9.3e-19 68.3 0.0 1.6e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain Gal-bind_lectin PF00337.22 KXG47878.1 - 2.6e-08 33.5 0.0 1e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Galactoside-binding lectin AP_endonuc_2 PF01261.24 KXG47879.1 - 1e-26 93.7 0.0 1.6e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AMP-binding PF00501.28 KXG47880.1 - 5.4e-58 196.6 0.0 3.2e-57 194.0 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG47880.1 - 0.00048 21.1 0.0 0.0012 19.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UQ_con PF00179.26 KXG47881.1 - 9.4e-19 67.5 0.0 1.4e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXG47881.1 - 0.048 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 RWD domain F_bP_aldolase PF01116.20 KXG47881.1 - 0.073 12.5 0.1 0.093 12.2 0.1 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II BRE PF06113.12 KXG47881.1 - 0.23 10.3 0.0 0.32 9.8 0.0 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) MGC-24 PF05283.11 KXG47881.1 - 0.42 11.0 7.5 0.38 11.2 3.5 2.1 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DHHC PF01529.20 KXG47882.1 - 1.4e-37 128.8 8.4 2.8e-37 127.8 8.4 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Nod_GRP PF07806.11 KXG47882.1 - 0.34 10.8 4.4 1.1 9.2 4.4 1.9 1 0 0 1 1 1 0 Nodule-specific GRP repeat Yip1 PF04893.17 KXG47882.1 - 4.6 6.9 14.4 0.13 12.0 3.5 2.2 2 0 0 2 2 2 0 Yip1 domain Rhomboid PF01694.22 KXG47883.1 - 4e-31 108.0 7.4 4e-31 108.0 7.4 1.7 3 0 0 3 3 3 1 Rhomboid family Kinetochor_Ybp2 PF08568.10 KXG47884.1 - 1.8e-148 495.9 0.0 2.2e-148 495.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin PLDc_2 PF13091.6 KXG47885.1 - 1e-16 61.1 0.0 2.8e-06 27.3 0.0 3.6 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KXG47885.1 - 1.5e-13 50.3 1.7 1.6e-05 24.9 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif bZIP_1 PF00170.21 KXG47886.1 - 0.0054 16.8 3.3 0.01 15.9 3.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor HR1 PF02185.16 KXG47886.1 - 0.025 14.7 5.9 0.025 14.7 5.9 1.7 2 0 0 2 2 2 0 Hr1 repeat TBK1_CCD1 PF18394.1 KXG47886.1 - 0.051 13.1 0.3 0.077 12.6 0.3 1.2 1 0 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 DUF719 PF05334.13 KXG47886.1 - 0.1 12.8 0.5 0.14 12.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF719) DUF4525 PF15027.6 KXG47886.1 - 0.16 11.7 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Gp58 PF07902.11 KXG47886.1 - 1.2 7.4 5.8 1.6 6.9 5.8 1.1 1 0 0 1 1 1 0 gp58-like protein FAD_binding_3 PF01494.19 KXG47887.1 - 5.2e-18 65.4 0.0 2.7e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.24 KXG47887.1 - 1.4e-05 24.6 0.2 0.014 14.7 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 KXG47887.1 - 5e-05 23.1 0.7 0.00071 19.3 0.5 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXG47887.1 - 0.00028 20.3 2.5 0.34 10.1 0.1 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXG47887.1 - 0.00048 19.3 0.6 0.39 9.7 0.4 3.0 4 0 0 4 4 4 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXG47887.1 - 0.011 15.9 0.2 0.027 14.7 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG47887.1 - 0.02 14.1 4.2 0.072 12.3 2.2 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG47887.1 - 0.063 12.4 0.2 0.12 11.4 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KXG47887.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF2530 PF10745.9 KXG47887.1 - 1.1 9.5 5.7 0.95 9.7 1.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Pyr_redox PF00070.27 KXG47887.1 - 3.7 8.2 4.4 5.6 7.6 0.4 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FA_hydroxylase PF04116.13 KXG47888.1 - 2.4e-21 76.5 11.8 2.4e-21 76.5 11.8 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Cyanate_lyase PF02560.14 KXG47889.1 - 2.1e-32 110.8 0.0 3e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.22 KXG47889.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix zf-C2H2_4 PF13894.6 KXG47890.1 - 0.004 17.9 12.9 0.68 10.9 0.3 4.9 5 0 0 5 5 5 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXG47890.1 - 0.055 13.5 5.4 1.2 9.2 0.9 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXG47890.1 - 0.18 12.3 12.6 11 6.8 0.5 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type Elf1 PF05129.13 KXG47890.1 - 0.19 11.8 2.2 0.18 11.9 0.7 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.6 KXG47890.1 - 0.24 11.9 0.1 0.24 11.9 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 KXG47890.1 - 7.7 6.9 15.2 1.7e+02 2.6 10.8 3.4 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Carb_kinase PF01256.17 KXG47891.1 - 0.16 11.4 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate kinase CYSTM PF12734.7 KXG47891.1 - 2.4 8.6 17.6 3 8.2 17.6 1.4 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Mt_ATP-synt_B PF05405.14 KXG47892.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ank_2 PF12796.7 KXG47893.1 - 6.5e-14 52.3 0.1 1.1e-06 29.1 0.0 3.4 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG47893.1 - 1.1e-12 46.9 1.1 0.0048 17.3 0.0 6.2 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 KXG47893.1 - 4.7e-08 33.1 0.6 0.64 10.6 0.1 4.9 4 1 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KXG47893.1 - 1.1e-07 32.3 0.9 0.0078 16.8 0.0 4.8 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG47893.1 - 0.00069 19.9 0.3 0.024 15.0 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) TetR_C_23 PF17931.1 KXG47893.1 - 0.02 15.0 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PH_10 PF15411.6 KXG47894.1 - 2.4e-26 92.4 0.0 4.3e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KXG47894.1 - 4.6e-12 46.5 0.0 7.7e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXG47894.1 - 6.9e-11 42.3 0.0 3.8e-10 39.9 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXG47894.1 - 1.8e-06 28.5 0.0 4.4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 KXG47894.1 - 0.00015 22.0 7.9 0.00029 21.1 7.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXG47894.1 - 0.0074 16.2 7.7 0.013 15.4 7.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KXG47894.1 - 0.012 15.3 3.0 0.025 14.3 3.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXG47894.1 - 0.032 14.1 7.2 0.06 13.2 7.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXG47894.1 - 0.033 14.5 4.2 0.071 13.4 4.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KXG47894.1 - 0.033 13.8 8.7 0.019 14.6 5.5 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type NlpE_C PF17185.4 KXG47894.1 - 0.14 12.5 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 NlpE C-terminal OB domain zf-C3HC4 PF00097.25 KXG47894.1 - 0.16 11.9 7.1 0.3 11.0 7.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXG47894.1 - 0.17 11.8 4.6 0.3 11.0 4.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) preSET_CXC PF18264.1 KXG47894.1 - 0.57 10.7 2.8 1.2 9.6 2.8 1.5 1 0 0 1 1 1 0 CXC domain zf-RING-like PF08746.11 KXG47894.1 - 1.3 9.3 6.8 2.5 8.5 6.8 1.4 1 0 0 1 1 1 0 RING-like domain Cpn60_TCP1 PF00118.24 KXG47895.1 - 3e-147 491.2 7.0 3.8e-147 490.9 7.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M48 PF01435.18 KXG47895.1 - 1.5e-35 122.8 0.0 5.6e-34 117.6 0.0 2.4 2 0 0 2 2 2 1 Peptidase family M48 Ribosomal_L12 PF00542.19 KXG47896.1 - 3.3e-20 72.2 3.3 3.8e-19 68.8 2.8 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KXG47896.1 - 5.2e-13 48.5 6.6 5.2e-13 48.5 6.6 3.1 4 1 0 4 4 4 1 Ribosomal protein L7/L12 dimerisation domain SpoVIF PF14069.6 KXG47896.1 - 0.051 13.4 0.3 0.28 11.0 0.0 2.1 2 1 0 2 2 2 0 Stage VI sporulation protein F TPR_7 PF13176.6 KXG47897.1 - 0.0024 17.8 0.2 2.2 8.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXG47897.1 - 0.024 15.1 1.0 0.27 11.8 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXG47897.1 - 0.036 14.7 4.4 0.98 10.2 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXG47897.1 - 0.06 14.2 1.6 2.8 9.0 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG47897.1 - 0.73 10.1 3.2 11 6.3 0.1 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Velvet PF11754.8 KXG47898.1 - 4.9e-58 197.0 0.0 6.3e-57 193.4 0.0 2.1 1 1 0 1 1 1 1 Velvet factor Auts2 PF15336.6 KXG47898.1 - 0.0029 17.7 2.3 0.0029 17.7 2.3 2.0 2 0 0 2 2 2 1 Autism susceptibility gene 2 protein DUF1143 PF06608.11 KXG47898.1 - 0.46 10.5 2.8 0.71 9.9 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) DUF3915 PF13054.6 KXG47898.1 - 3.7 7.6 5.4 6.4 6.8 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) SYF2 PF08231.12 KXG47900.1 - 4.3e-56 189.7 15.8 4.3e-56 189.7 15.8 2.2 2 1 0 2 2 2 1 SYF2 splicing factor Adenylsucc_synt PF00709.21 KXG47900.1 - 0.09 11.7 0.7 0.17 10.7 0.2 1.7 1 1 1 2 2 2 0 Adenylosuccinate synthetase NAD_binding_10 PF13460.6 KXG47901.1 - 8.1e-07 29.1 0.0 9e-06 25.7 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXG47901.1 - 4.2e-05 23.1 0.0 8.2e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXG47901.1 - 0.00011 21.3 0.0 0.00029 19.9 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KXG47901.1 - 0.01 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KXG47901.1 - 0.038 13.1 0.0 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXG47901.1 - 0.14 11.3 0.1 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein YEATS PF03366.16 KXG47902.1 - 1.6e-35 120.9 1.3 2.5e-35 120.3 1.3 1.3 1 0 0 1 1 1 1 YEATS family M16C_assoc PF08367.11 KXG47902.1 - 0.12 11.5 1.4 0.18 10.9 1.4 1.2 1 0 0 1 1 1 0 Peptidase M16C associated IDO PF01231.18 KXG47903.1 - 1.6e-145 485.2 0.0 1.9e-145 485.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 KXG47903.1 - 0.021 13.6 0.0 0.053 12.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) Aminotran_5 PF00266.19 KXG47904.1 - 5.1e-09 35.6 0.0 6.3e-08 32.0 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXG47904.1 - 0.024 14.0 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.18 KXG47905.1 - 8.5e-07 28.3 0.2 9.6e-06 24.8 0.1 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Epsilon_antitox PF08998.11 KXG47905.1 - 0.1 12.9 0.2 4.1 7.7 0.1 2.4 2 0 0 2 2 2 0 Bacterial epsilon antitoxin COX7a PF02238.15 KXG47906.1 - 9.4e-24 83.6 2.8 1.2e-23 83.3 2.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Thiamine_BP PF01910.17 KXG47908.1 - 2.3e-30 104.4 0.1 2.6e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Ins_P5_2-kin PF06090.12 KXG47909.1 - 4.3e-46 157.9 0.0 1.1e-45 156.5 0.0 1.6 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase NUDIX PF00293.28 KXG47911.1 - 1.6e-22 79.9 0.0 1.9e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KXG47911.1 - 0.00025 21.0 0.0 0.00044 20.2 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain IGR PF09597.10 KXG47911.1 - 0.12 12.6 0.0 0.59 10.3 0.0 2.0 2 0 0 2 2 2 0 IGR protein motif adh_short PF00106.25 KXG47912.1 - 2.1e-33 115.4 0.0 2.6e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG47912.1 - 5e-21 75.3 0.0 6.5e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG47912.1 - 4.7e-09 36.4 0.5 6.4e-08 32.7 0.5 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXG47912.1 - 3.4e-07 30.0 0.0 4.9e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXG47912.1 - 0.00056 19.1 0.0 0.00073 18.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.18 KXG47912.1 - 0.0013 18.9 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.6 KXG47912.1 - 0.0036 17.2 0.1 0.006 16.5 0.0 1.4 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXG47912.1 - 0.0049 16.3 0.1 0.011 15.1 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KXG47912.1 - 0.0057 16.9 0.0 0.021 15.1 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KXG47912.1 - 0.016 14.4 0.2 0.023 13.8 0.2 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein UPF0146 PF03686.13 KXG47912.1 - 0.035 14.0 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) VasI PF11319.8 KXG47912.1 - 0.053 13.2 0.0 0.098 12.3 0.0 1.5 1 1 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 DUF1776 PF08643.10 KXG47912.1 - 0.055 12.8 0.3 0.18 11.1 0.1 1.9 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.19 KXG47912.1 - 0.065 12.2 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Gp_dh_N PF00044.24 KXG47912.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain LOR PF04525.12 KXG47913.1 - 3.6e-06 26.7 0.0 1.3e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 LURP-one-related MFS_1 PF07690.16 KXG47914.1 - 6.8e-22 77.9 77.3 3e-20 72.5 51.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 KXG47914.1 - 0.026 13.2 19.3 0.023 13.3 14.1 2.9 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like Metallophos PF00149.28 KXG47916.1 - 2e-33 116.7 0.1 2.8e-33 116.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXG47916.1 - 3.2e-13 49.9 0.2 5.6e-13 49.1 0.2 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Polysacc_deac_1 PF01522.21 KXG47917.1 - 2.2e-29 101.9 0.0 3.8e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Creatininase PF02633.14 KXG47917.1 - 1.9e-06 27.5 0.0 3.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Creatinine amidohydrolase DUF1682 PF07946.14 KXG47918.1 - 6e-111 370.7 0.8 6.9e-111 370.5 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) YajC PF02699.15 KXG47918.1 - 0.037 13.9 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit DUF3301 PF11743.8 KXG47918.1 - 0.072 12.8 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) Haspin_kinase PF12330.8 KXG47920.1 - 2.5e-40 138.6 0.0 3.4e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain p450 PF00067.22 KXG47921.1 - 4.6e-76 256.4 0.0 5.5e-76 256.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nucleoside_tran PF01733.18 KXG47922.1 - 2.9e-44 151.7 13.7 3.1e-42 145.1 13.7 2.4 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 KXG47922.1 - 0.00035 19.6 25.1 0.00056 18.9 11.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2207 PF09972.9 KXG47922.1 - 0.0088 14.9 0.3 2 7.1 0.2 2.2 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) 7tm_3 PF00003.22 KXG47922.1 - 0.94 9.1 14.5 4.7 6.9 1.9 2.9 1 1 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR ABC_membrane PF00664.23 KXG47923.1 - 7.2e-52 176.7 9.6 9.3e-52 176.4 9.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXG47923.1 - 3.2e-36 124.9 0.0 7.3e-36 123.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KXG47923.1 - 3.6e-05 23.3 0.1 0.0039 16.7 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXG47923.1 - 0.0081 15.9 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KXG47923.1 - 0.013 15.9 0.1 0.047 14.1 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KXG47923.1 - 0.031 14.6 0.1 0.23 11.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXG47923.1 - 0.037 13.8 0.0 0.1 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KXG47923.1 - 0.044 14.2 0.0 0.24 11.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 KXG47923.1 - 0.049 12.4 0.3 0.25 10.1 0.1 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 KXG47923.1 - 0.054 13.2 0.1 0.44 10.2 0.0 2.2 2 1 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.6 KXG47923.1 - 0.067 13.4 1.2 1.4 9.3 0.6 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 KXG47923.1 - 0.15 11.8 0.0 2.6 7.8 0.0 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_23 PF13476.6 KXG47923.1 - 0.17 12.4 1.0 0.35 11.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain CDC37_N PF03234.14 KXG47924.1 - 9.2e-49 165.6 2.4 9.2e-49 165.6 2.4 2.6 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KXG47924.1 - 8.4e-42 141.8 0.1 2.6e-41 140.3 0.0 1.9 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KXG47924.1 - 5.3e-34 116.3 2.9 2e-33 114.5 2.4 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain DUF922 PF06037.11 KXG47924.1 - 0.067 13.0 0.0 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) EF-G-binding_N PF07299.11 KXG47924.1 - 0.34 11.5 5.1 2.6 8.6 0.1 4.1 3 1 1 4 4 4 0 Elongation factor G-binding protein, N-terminal DUF4407 PF14362.6 KXG47924.1 - 0.72 9.1 5.6 0.94 8.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Clathrin_lg_ch PF01086.17 KXG47925.1 - 1.2e-70 238.1 5.3 1.5e-70 237.9 5.3 1.1 1 0 0 1 1 1 1 Clathrin light chain CTD_bind PF04818.13 KXG47926.1 - 2.2e-16 60.4 0.1 5.8e-16 59.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CREPT PF16566.5 KXG47926.1 - 0.0055 16.9 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour DUF3277 PF11681.8 KXG47926.1 - 0.0078 16.1 0.1 0.38 10.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3277) CTK3 PF12243.8 KXG47926.1 - 0.071 13.1 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Cas9_Topo PF17894.1 KXG47926.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 Muted PF14942.6 KXG47926.1 - 0.11 12.9 0.9 0.22 11.9 0.9 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein SNARE PF05739.19 KXG47927.1 - 1.2e-13 50.8 0.4 1.2e-13 50.8 0.4 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KXG47927.1 - 2e-05 24.3 6.0 0.00085 19.1 0.5 2.3 2 0 0 2 2 2 2 Syntaxin HlyD_D4 PF16572.5 KXG47927.1 - 0.0091 15.8 0.1 0.023 14.6 0.1 1.7 1 0 0 1 1 1 1 Long alpha hairpin domain of cation efflux system protein, CusB Syntaxin_2 PF14523.6 KXG47927.1 - 0.017 15.5 0.5 0.017 15.5 0.5 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Chordopox_A13L PF05961.11 KXG47927.1 - 0.078 13.2 0.0 0.67 10.2 0.0 2.4 3 0 0 3 3 3 0 Chordopoxvirus A13L protein MCPsignal PF00015.21 KXG47927.1 - 0.21 11.4 7.6 0.13 12.1 1.3 2.8 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF641 PF04859.12 KXG47927.1 - 1.4 9.3 4.6 4 7.8 0.8 2.6 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) SlyX PF04102.12 KXG47927.1 - 5.3 7.7 6.1 7.5 7.3 0.1 3.2 2 2 2 4 4 4 0 SlyX EF-hand_1 PF00036.32 KXG47928.1 - 1.3e-41 137.0 11.6 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXG47928.1 - 3.6e-36 123.4 5.3 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KXG47928.1 - 1.9e-34 117.3 11.5 2.4e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KXG47928.1 - 3.8e-30 101.2 8.5 7.1e-09 34.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXG47928.1 - 6.8e-26 88.6 9.8 4.7e-06 25.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KXG47928.1 - 1.4e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KXG47928.1 - 6.8e-10 38.8 1.6 0.00078 19.4 0.3 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KXG47928.1 - 5.9e-09 36.2 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KXG47928.1 - 1e-06 28.6 0.1 0.008 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KXG47928.1 - 6.4e-06 26.2 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KXG47928.1 - 9.4e-05 23.2 0.2 0.0025 18.6 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 KXG47928.1 - 0.00013 21.9 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 KXG47928.1 - 0.00059 19.8 1.6 0.52 10.2 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 KXG47928.1 - 0.00062 20.1 0.7 0.66 10.3 0.1 2.6 2 1 1 3 3 3 2 RNA polymerase Rpb4 Dockerin_1 PF00404.18 KXG47928.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 KXG47928.1 - 0.0057 15.3 0.0 0.0058 15.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KXG47928.1 - 0.0084 16.0 0.7 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 KXG47928.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 KXG47928.1 - 0.023 14.9 0.0 0.18 12.0 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein RuvA_C PF07499.13 KXG47928.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain dCache_2 PF08269.11 KXG47928.1 - 0.061 12.5 0.1 1 8.5 0.1 2.1 1 1 1 2 2 2 0 Cache domain MotA_activ PF09114.10 KXG47928.1 - 0.061 13.5 0.3 0.91 9.7 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain DUF4497 PF14924.6 KXG47928.1 - 0.092 13.2 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RloB PF13707.6 KXG47928.1 - 0.11 12.7 1.3 0.72 10.0 0.2 2.1 1 1 1 2 2 2 0 RloB-like protein DUF5132 PF17195.4 KXG47928.1 - 0.16 12.1 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Med20 PF08612.11 KXG47929.1 - 3.3e-78 262.1 0.0 3.8e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Glyco_hydro_47 PF01532.20 KXG47930.1 - 1.2e-180 601.4 0.0 1.3e-180 601.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CstA PF02554.14 KXG47931.1 - 0.2 10.5 11.9 0.48 9.3 11.9 1.5 1 1 0 1 1 1 0 Carbon starvation protein CstA FA_desaturase PF00487.24 KXG47931.1 - 0.21 11.4 9.8 5.2 6.8 5.1 2.4 2 1 0 2 2 2 0 Fatty acid desaturase Phage_holin_2_1 PF04971.12 KXG47931.1 - 0.3 11.1 1.9 0.39 10.7 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage P21 holin S AA_permease_2 PF13520.6 KXG47932.1 - 2.6e-55 188.0 49.0 3.2e-55 187.7 49.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG47932.1 - 3e-23 82.1 40.0 4.2e-23 81.7 40.0 1.1 1 0 0 1 1 1 1 Amino acid permease FAD_binding_1 PF00667.20 KXG47933.1 - 1e-45 156.1 0.0 1.4e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KXG47933.1 - 7.5e-10 39.4 0.0 1.7e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PTR2 PF00854.21 KXG47935.1 - 6.4e-53 180.0 0.1 4.2e-37 127.9 0.0 2.4 1 1 1 2 2 2 2 POT family Imm35 PF15567.6 KXG47935.1 - 0.034 14.3 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 35 Homeobox_KN PF05920.11 KXG47936.1 - 5.9e-22 77.3 0.2 1.1e-21 76.4 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KXG47936.1 - 3.3e-07 30.0 0.1 5.6e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Homeodomain Alpha-amylase PF00128.24 KXG47938.1 - 1.5e-68 231.9 4.2 2.1e-68 231.4 4.2 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KXG47938.1 - 1.9e-19 69.7 0.1 6.5e-18 64.8 0.1 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1966) Glyco_hydro_31 PF01055.26 KXG47939.1 - 1.8e-153 511.9 2.0 2.5e-153 511.4 2.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KXG47939.1 - 5.1e-32 110.5 0.1 9.5e-32 109.6 0.1 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KXG47939.1 - 0.00011 22.4 0.1 0.00049 20.4 0.1 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like Fungal_trans PF04082.18 KXG47940.1 - 1.3e-10 40.8 0.0 1.8e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.6 KXG47941.1 - 1.1e-15 57.9 0.0 1.5e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG47941.1 - 8.4e-12 45.6 0.0 4.9e-11 43.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG47941.1 - 5.4e-11 43.1 0.0 1.1e-10 42.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG47941.1 - 1e-09 39.0 0.0 7.4e-08 33.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG47941.1 - 6.5e-08 32.5 0.0 1.8e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Hydrolase PF00702.26 KXG47942.1 - 1.4e-23 84.3 0.0 2.2e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXG47942.1 - 3.1e-17 62.7 10.5 2.8e-10 40.0 0.0 2.4 1 1 1 2 2 2 2 E1-E2 ATPase Hydrolase_3 PF08282.12 KXG47942.1 - 2.9e-06 27.2 1.1 6.4e-05 22.8 0.2 2.5 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXG47942.1 - 0.017 15.2 0.0 0.048 13.8 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXG47942.1 - 0.076 13.1 0.0 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MauE PF07291.11 KXG47942.1 - 0.45 10.3 8.5 0.12 12.1 2.4 2.3 2 0 0 2 2 2 0 Methylamine utilisation protein MauE BRAP2 PF07576.12 KXG47944.1 - 3e-34 117.2 0.0 5.1e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KXG47944.1 - 2.8e-19 69.2 7.0 5.2e-19 68.3 5.4 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KXG47944.1 - 1.4e-08 34.9 9.4 1.4e-08 34.9 9.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXG47944.1 - 4.6e-06 26.4 9.7 4.6e-06 26.4 9.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXG47944.1 - 0.00011 21.9 4.8 0.00011 21.9 4.8 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXG47944.1 - 0.0002 21.2 8.8 0.0002 21.2 8.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXG47944.1 - 0.00024 20.9 16.2 0.00033 20.5 5.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXG47944.1 - 0.00029 20.7 8.2 0.00029 20.7 8.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXG47944.1 - 0.00039 20.6 7.3 0.00039 20.6 7.3 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXG47944.1 - 0.0004 20.3 5.5 0.0004 20.3 5.5 2.7 2 1 0 2 2 1 1 RING-type zinc-finger zf-RING_6 PF14835.6 KXG47944.1 - 0.0011 18.7 2.6 0.0032 17.3 2.6 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KXG47944.1 - 0.0055 16.7 5.3 0.021 14.8 5.3 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXG47944.1 - 0.077 12.9 20.1 0.04 13.8 9.9 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 ZapB PF06005.12 KXG47944.1 - 0.18 12.3 3.2 0.36 11.3 0.1 2.4 1 1 1 2 2 2 0 Cell division protein ZapB zf-RING_4 PF14570.6 KXG47944.1 - 0.95 9.3 6.9 2.1 8.2 6.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PRKG1_interact PF15898.5 KXG47944.1 - 1.9 9.4 6.2 0.83 10.6 2.7 2.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain TPR_MLP1_2 PF07926.12 KXG47944.1 - 2.3 8.3 10.8 4.7 7.3 10.8 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ubiquitin PF00240.23 KXG47945.1 - 4.4e-135 439.7 20.4 3.3e-33 113.3 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 KXG47945.1 - 6.6e-64 211.7 21.0 2e-15 56.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXG47945.1 - 8.1e-23 80.7 10.7 0.00043 20.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 KXG47945.1 - 1.7e-16 59.9 3.0 0.027 14.4 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KXG47945.1 - 3.9e-15 56.0 8.2 0.028 14.8 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXG47945.1 - 2.1e-14 53.6 2.6 0.12 12.4 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KXG47945.1 - 5.6e-13 49.4 1.4 0.37 11.4 0.0 4.2 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KXG47945.1 - 5.2e-11 42.7 0.8 0.52 10.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 KXG47945.1 - 3.7e-07 30.1 24.0 16 5.6 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 KXG47945.1 - 2.9e-06 26.8 0.4 1.8 7.8 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 KXG47945.1 - 3.8e-06 27.0 2.5 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 KXG47945.1 - 7.1e-06 26.3 0.0 30 5.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 KXG47945.1 - 1.2e-05 25.0 4.7 10 6.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain Big_7 PF17957.1 KXG47945.1 - 4e-05 24.3 0.1 52 4.7 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 KXG47945.1 - 0.00014 21.9 4.3 7.1 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KXG47945.1 - 0.00042 19.8 0.0 23 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) YcgR_2 PF12945.7 KXG47945.1 - 0.00091 19.3 6.2 29 4.9 0.1 4.3 4 0 0 4 4 4 0 Flagellar protein YcgR DUF493 PF04359.14 KXG47945.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 KXG47945.1 - 0.0037 16.9 0.0 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 KXG47945.1 - 0.0052 17.4 1.0 1.4e+02 3.1 0.0 4.2 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 KXG47945.1 - 0.0068 16.5 0.0 91 3.3 0.0 4.3 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 KXG47945.1 - 0.11 12.7 5.8 1.1e+02 3.1 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Baculo_p48 PF04878.13 KXG47945.1 - 0.12 11.2 0.0 61 2.4 0.0 3.0 3 0 0 3 3 3 0 Baculovirus P48 protein Tash_PEST PF07708.11 KXG47945.1 - 0.14 12.4 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Myosin_N PF02736.19 KXG47945.1 - 0.23 11.3 6.3 1.1e+02 2.8 0.0 5.2 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain HAMP_N3 PF18575.1 KXG47945.1 - 0.23 11.0 1.5 2e+02 1.6 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 PI3K_p85B PF02192.16 KXG47945.1 - 1.9 8.3 9.3 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Zn_clus PF00172.18 KXG47946.1 - 0.004 17.2 7.7 0.0074 16.4 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPX PF03105.19 KXG47946.1 - 2.8 7.8 8.7 5.4 6.8 8.7 1.5 1 0 0 1 1 1 0 SPX domain SelP_N PF04592.14 KXG47946.1 - 3.9 6.8 12.6 11 5.4 12.6 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.9 KXG47946.1 - 4.3 5.8 10.1 6 5.3 10.1 1.1 1 0 0 1 1 1 0 Macoilin family Prenyltrans PF00432.21 KXG47947.1 - 2.4e-37 126.4 27.1 8.2e-12 44.7 0.8 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KXG47947.1 - 0.00033 19.9 0.0 0.16 11.1 0.0 2.3 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KXG47947.1 - 0.001 18.3 0.0 0.0075 15.4 0.1 1.9 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain dsrm PF00035.26 KXG47948.1 - 0.00021 21.9 0.0 0.00053 20.6 0.0 1.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KXG47948.1 - 0.0045 17.2 0.5 0.016 15.5 0.5 1.8 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 APH PF01636.23 KXG47949.1 - 5e-15 56.1 0.0 1.7e-06 28.2 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Grg1 PF11034.8 KXG47950.1 - 1e-30 105.8 12.4 1.1e-30 105.6 12.4 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 PTPLA PF04387.14 KXG47952.1 - 5.8e-56 188.8 4.2 9.7e-56 188.0 4.2 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Hpt PF01627.23 KXG47953.1 - 4.4e-09 36.5 0.0 9.3e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Hpt domain CdiI_2 PF18593.1 KXG47953.1 - 0.053 14.2 1.1 0.26 12.0 0.0 2.3 2 0 0 2 2 2 0 CdiI immunity protein NusB PF01029.18 KXG47953.1 - 0.063 13.5 0.1 0.063 13.5 0.1 2.2 2 1 0 2 2 2 0 NusB family DUF1788 PF08747.11 KXG47953.1 - 3.5 7.7 6.3 2.1 8.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) MCU PF04678.13 KXG47955.1 - 3.4e-26 92.4 0.1 7.7e-26 91.3 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Adaptin_binding PF10199.9 KXG47956.1 - 8.1e-19 68.4 0.8 1.6e-18 67.4 0.8 1.5 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 LSM PF01423.22 KXG47957.1 - 1e-15 57.2 0.4 1.4e-15 56.7 0.4 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXG47957.1 - 0.061 13.5 0.1 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain PGP_phosphatase PF09419.10 KXG47958.1 - 7.7e-60 201.3 0.0 9.1e-60 201.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KXG47958.1 - 0.00019 21.4 0.0 0.00038 20.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Homeodomain PF00046.29 KXG47959.1 - 4.3e-19 68.1 2.3 8.6e-19 67.1 2.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXG47959.1 - 0.0046 16.8 0.7 0.01 15.7 0.7 1.6 1 0 0 1 1 1 1 Homeobox KN domain ANF_receptor PF01094.28 KXG47959.1 - 0.18 10.9 0.9 0.27 10.3 0.9 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region Fungal_trans_2 PF11951.8 KXG47960.1 - 1.8e-24 86.3 0.3 2.2e-24 86.0 0.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_3 PF00202.21 KXG47961.1 - 6.4e-87 291.8 0.0 8.2e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXG47961.1 - 4.4e-05 22.8 0.0 0.00048 19.4 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II TonB_2 PF13103.6 KXG47961.1 - 0.046 14.0 0.0 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 TonB C terminal Acetyltransf_3 PF13302.7 KXG47963.1 - 6.6e-15 56.0 0.0 8.8e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG47963.1 - 0.00016 21.9 0.0 0.00023 21.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MFS_1 PF07690.16 KXG47964.1 - 6.2e-28 97.7 56.5 1.1e-23 83.8 35.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG47964.1 - 4e-16 58.9 26.0 4.5e-14 52.2 5.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter adh_short PF00106.25 KXG47965.1 - 2.2e-36 125.2 0.0 3.3e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase MFS_1 PF07690.16 KXG47965.1 - 2.2e-29 102.5 21.0 3.7e-29 101.7 21.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily adh_short_C2 PF13561.6 KXG47965.1 - 1.4e-21 77.1 0.0 2.3e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG47965.1 - 1.1e-05 25.4 0.0 4.2e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KXG47965.1 - 0.00033 20.6 0.1 0.00055 19.9 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding ApbA PF02558.16 KXG47965.1 - 0.016 14.9 0.6 0.14 11.8 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 KXG47965.1 - 0.016 14.6 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KXG47965.1 - 0.22 11.6 0.0 0.42 10.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PAD_porph PF04371.15 KXG47966.1 - 5.3e-88 295.4 0.0 6.2e-88 295.2 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase DUF563 PF04577.14 KXG47967.1 - 4.8e-35 121.6 0.0 6.5e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Swm2 PF17083.5 KXG47967.1 - 0.0054 16.7 0.0 0.019 15.0 0.0 1.9 2 0 0 2 2 2 1 Nucleolar protein Swm2 PhoLip_ATPase_C PF16212.5 KXG47968.1 - 1.5e-70 237.8 20.2 1.5e-70 237.8 20.2 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXG47968.1 - 2.8e-23 81.4 2.7 9e-23 79.8 0.8 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KXG47968.1 - 4.3e-13 49.2 0.0 4.3e-13 49.2 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KXG47968.1 - 1.9e-12 47.9 2.4 9.7e-06 26.0 0.2 3.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXG47968.1 - 7.8e-12 45.1 0.1 1.1e-10 41.4 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXG47968.1 - 0.003 17.3 0.2 0.011 15.5 0.1 1.7 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1345 PF07077.11 KXG47968.1 - 0.29 10.8 4.1 10 5.8 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) COX6C PF02937.15 KXG47968.1 - 0.37 11.0 2.6 0.3 11.3 0.1 2.2 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIc vWA-TerF-like PF10138.9 KXG47969.1 - 1.4e-06 28.6 0.0 2.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus PhyH PF05721.13 KXG47970.1 - 1.1e-22 81.3 0.0 4.6e-22 79.3 0.0 1.9 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) HD PF01966.22 KXG47970.1 - 1.1e-07 32.1 0.4 7.2e-07 29.5 0.4 2.0 2 0 0 2 2 2 1 HD domain MIOX PF05153.15 KXG47970.1 - 0.00081 19.0 0.1 0.0036 16.9 0.0 1.9 2 0 0 2 2 2 1 Myo-inositol oxygenase HDOD PF08668.12 KXG47970.1 - 0.0025 17.3 0.1 0.0052 16.3 0.1 1.5 1 0 0 1 1 1 1 HDOD domain HD_4 PF13328.6 KXG47970.1 - 0.014 15.1 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 HD domain 2OG-FeII_Oxy_5 PF13759.6 KXG47970.1 - 0.067 13.6 0.0 0.22 12.0 0.0 1.8 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Sugar_tr PF00083.24 KXG47971.1 - 3e-39 135.2 29.4 6.4e-26 91.2 11.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXG47971.1 - 1.3e-26 93.3 33.9 6.7e-14 51.6 14.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG47971.1 - 0.1 11.0 6.7 0.031 12.7 0.9 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF4229 PF14012.6 KXG47971.1 - 1.4 9.1 12.5 1 9.5 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) GFO_IDH_MocA PF01408.22 KXG47972.1 - 2.5e-14 54.1 0.0 5.7e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXG47972.1 - 0.0008 20.0 0.1 0.0018 18.9 0.1 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KXG47972.1 - 0.035 14.5 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SRP_TPR_like PF17004.5 KXG47973.1 - 7e-22 77.6 2.9 2.1e-20 72.9 1.2 2.3 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 KXG47973.1 - 1.2e-17 64.0 2.2 1.2e-17 64.0 2.2 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 KXG47973.1 - 4e-08 33.7 12.0 0.26 11.8 0.3 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXG47973.1 - 2.2e-06 28.0 10.3 17 6.6 0.0 7.6 4 1 3 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXG47973.1 - 1.7e-05 24.6 7.4 2.6 8.4 0.1 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXG47973.1 - 0.00019 21.4 3.2 8.7 6.8 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG47973.1 - 0.00038 20.6 10.6 1.1 9.5 3.6 4.6 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KXG47973.1 - 0.0028 18.2 13.7 0.11 13.2 0.2 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXG47973.1 - 0.036 14.1 5.5 7.3 6.9 0.1 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 KXG47973.1 - 0.068 13.4 0.1 27 5.3 0.0 4.0 5 0 0 5 5 5 0 PPR repeat Cytochrom_B562 PF07361.11 KXG47973.1 - 0.21 12.3 4.2 3.6 8.3 1.7 3.0 3 0 0 3 3 2 0 Cytochrome b562 TPR_1 PF00515.28 KXG47973.1 - 0.35 10.8 6.1 3.5 7.6 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXG47973.1 - 0.58 10.9 10.4 28 5.6 0.3 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3405 PF11885.8 KXG47974.1 - 3.3e-153 511.0 4.0 2.8e-152 508.0 4.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) Phospholamban PF04272.14 KXG47974.1 - 0.042 13.3 0.1 0.077 12.5 0.1 1.3 1 0 0 1 1 1 0 Phospholamban Fringe PF02434.16 KXG47975.1 - 1.4e-09 37.8 0.0 2.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 KXG47975.1 - 6.7e-08 32.2 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 zf-C2H2 PF00096.26 KXG47976.1 - 7.1e-19 67.1 28.2 3.5e-05 24.0 1.7 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXG47976.1 - 2.3e-18 65.7 29.6 1.4e-06 28.5 1.5 5.6 6 0 0 6 6 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXG47976.1 - 2.7e-10 40.2 25.5 0.004 17.9 1.3 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXG47976.1 - 8.1e-06 26.0 2.5 0.5 10.7 0.1 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXG47976.1 - 0.00089 19.6 15.0 0.012 16.0 0.3 4.0 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KXG47976.1 - 0.013 15.1 2.3 1.1 8.9 0.2 2.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger FOXP-CC PF16159.5 KXG47976.1 - 0.013 16.1 10.5 0.2 12.3 0.6 3.4 3 1 1 4 4 4 0 FOXP coiled-coil domain DDE_Tnp_1_6 PF13751.6 KXG47976.1 - 0.018 15.2 0.5 0.047 13.9 0.5 1.6 1 0 0 1 1 1 0 Transposase DDE domain zf-C2H2_11 PF16622.5 KXG47976.1 - 0.019 14.7 0.8 0.019 14.7 0.8 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 KXG47976.1 - 0.021 15.0 1.1 2.9 8.0 0.1 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger Yippee-Mis18 PF03226.14 KXG47976.1 - 0.3 11.3 1.8 17 5.7 0.1 2.2 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF4764 PF15961.5 KXG47976.1 - 1.6 7.3 7.8 0.065 11.9 0.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) Zn_ribbon_recom PF13408.6 KXG47976.1 - 4.2 8.0 7.1 1.9 9.0 2.7 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain HNH PF01844.23 KXG47976.1 - 6.8 7.0 8.4 7.7 6.8 0.1 3.8 4 0 0 4 4 4 0 HNH endonuclease CorA PF01544.18 KXG47977.1 - 1.5e-08 34.4 0.6 3.6e-08 33.1 0.6 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein EMC3_TMCO1 PF01956.16 KXG47977.1 - 0.0075 16.0 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF2417 PF10329.9 KXG47977.1 - 0.049 13.0 0.2 10 5.5 0.1 2.5 2 0 0 2 2 2 0 Region of unknown function (DUF2417) HAD_2 PF13419.6 KXG47978.1 - 2.7e-18 66.7 0.0 4.8e-18 65.9 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXG47978.1 - 2.6e-06 27.9 0.0 0.001 19.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXG47978.1 - 1.5e-05 24.9 0.0 4.3e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like PEP_mutase PF13714.6 KXG47979.1 - 1.3e-69 234.3 6.4 1.4e-69 234.2 6.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ComA PF02679.15 KXG47979.1 - 0.056 12.9 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Aconitase_B_N PF11791.8 KXG47979.1 - 0.06 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Aconitate B N-terminal domain ELL PF10390.9 KXG47980.1 - 0.0007 19.2 0.2 0.0007 19.2 0.2 2.2 2 1 0 2 2 2 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.13 KXG47980.1 - 0.14 12.9 3.8 0.4 11.4 1.0 2.5 2 0 0 2 2 2 0 Occludin homology domain DUF155 PF02582.14 KXG47981.1 - 8.4e-52 175.8 0.0 1.4e-51 175.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 HAD_2 PF13419.6 KXG47982.1 - 1.8e-05 24.9 0.0 3.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXG47982.1 - 0.0047 17.0 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Mrr_N PF14338.6 KXG47982.1 - 0.043 13.9 0.0 0.7 10.1 0.0 2.3 2 0 0 2 2 2 0 Mrr N-terminal domain NIF PF03031.18 KXG47982.1 - 0.096 12.5 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase Transferase PF02458.15 KXG47983.1 - 1.1e-08 34.2 0.0 0.0007 18.4 0.0 2.4 3 0 0 3 3 3 2 Transferase family Aminotran_1_2 PF00155.21 KXG47984.1 - 2.2e-92 310.0 0.0 2.5e-92 309.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SART-1 PF03343.13 KXG47985.1 - 4.3e-187 623.5 65.2 4.9e-187 623.3 65.2 1.0 1 0 0 1 1 1 1 SART-1 family SurA_N_2 PF13623.6 KXG47985.1 - 0.053 13.4 1.3 0.19 11.6 0.3 2.5 2 0 0 2 2 2 0 SurA N-terminal domain PTH2 PF01981.16 KXG47986.1 - 1.2e-41 141.7 0.1 1.6e-41 141.3 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Nop14 PF04147.12 KXG47986.1 - 0.2 9.8 2.7 0.23 9.6 2.7 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KXG47986.1 - 5.8 4.9 7.0 7.1 4.6 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi HMGL-like PF00682.19 KXG47988.1 - 2.5e-78 263.3 0.5 3.9e-78 262.7 0.5 1.3 1 0 0 1 1 1 1 HMGL-like Pyridoxal_deC PF00282.19 KXG47988.1 - 2.3e-18 66.1 0.0 3.7e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXG47988.1 - 1.4e-08 34.1 0.0 9e-08 31.5 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXG47988.1 - 2.4e-06 27.0 0.0 5.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXG47988.1 - 0.0004 19.8 0.0 0.00067 19.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KXG47988.1 - 0.02 13.5 0.0 0.26 9.8 0.0 2.4 3 0 0 3 3 3 0 Cys/Met metabolism PLP-dependent enzyme Ribosomal_L30 PF00327.20 KXG47989.1 - 3.9e-15 55.5 0.2 6.1e-15 54.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Sec6 PF06046.13 KXG47990.1 - 3.2e-173 577.2 8.5 3.2e-173 577.2 8.5 1.7 2 0 0 2 2 2 1 Exocyst complex component Sec6 Myb_DNA-bind_5 PF13873.6 KXG47990.1 - 0.15 12.1 1.2 42 4.3 0.0 3.7 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain Vps53_N PF04100.12 KXG47990.1 - 0.52 9.2 10.3 0.19 10.6 1.7 2.5 2 0 0 2 2 2 0 Vps53-like, N-terminal HEAT_2 PF13646.6 KXG47990.1 - 1.2 9.5 5.7 1.8 9.0 0.4 4.0 3 2 0 3 3 3 0 HEAT repeats DUF737 PF05300.11 KXG47990.1 - 4.6 7.6 6.3 5.2 7.4 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF737) PEP-utilisers_N PF05524.13 KXG47990.1 - 6.6 6.9 7.1 14 5.9 4.4 3.0 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal AKAP7_NLS PF10469.9 KXG47991.1 - 2.3e-10 40.7 0.0 3.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain RED_N PF07808.13 KXG47992.1 - 1.5e-07 31.3 1.9 3.7e-07 30.0 1.9 1.6 1 0 0 1 1 1 1 RED-like protein N-terminal region GvpG PF05120.12 KXG47992.1 - 4.3 7.4 5.3 0.62 10.1 0.4 2.2 3 0 0 3 3 3 0 Gas vesicle protein G zf-UBR PF02207.20 KXG47993.1 - 8.5e-19 67.5 15.0 1.8e-18 66.4 15.0 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KXG47993.1 - 0.00046 19.9 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 KXG47993.1 - 0.0044 17.3 0.8 0.0044 17.3 0.8 3.5 3 1 1 4 4 4 1 Ring finger domain DNA_pol_phi PF04931.13 KXG47993.1 - 4.8 5.2 17.3 14 3.6 17.3 1.7 2 0 0 2 2 2 0 DNA polymerase phi Nop14 PF04147.12 KXG47993.1 - 6.8 4.8 10.5 12 3.9 10.5 1.3 1 0 0 1 1 1 0 Nop14-like family UCR_UQCRX_QCR9 PF05365.12 KXG47994.1 - 4e-24 84.3 3.7 4.9e-24 84.0 3.7 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4203 PF13886.6 KXG47994.1 - 0.003 17.3 0.0 0.003 17.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Mago-bind PF09282.10 KXG47995.1 - 1.4e-14 53.6 4.3 2.5e-14 52.8 4.3 1.4 1 0 0 1 1 1 1 Mago binding Amino_oxidase PF01593.24 KXG47996.1 - 8.2e-29 101.2 0.0 1.2e-28 100.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXG47996.1 - 2.3e-13 50.2 0.3 9.9e-12 44.9 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXG47996.1 - 4.4e-05 23.2 0.1 0.00023 20.9 0.0 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase zf-CCCH_2 PF14608.6 KXG47997.1 - 8.2e-12 45.1 60.9 0.00037 20.9 14.0 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 KXG47997.1 - 0.0017 18.6 0.0 0.0029 17.9 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) p450 PF00067.22 KXG47998.1 - 6.7e-57 193.2 0.0 8.9e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FGGY_C PF02782.16 KXG47999.1 - 6.7e-74 247.9 0.5 1.1e-73 247.2 0.5 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXG47999.1 - 3.5e-68 229.8 0.0 4.7e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KXG47999.1 - 0.017 14.7 0.2 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MIP PF00230.20 KXG48000.1 - 1.1e-48 165.9 3.0 1.5e-48 165.5 3.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein GYF PF02213.16 KXG48001.1 - 1.2e-18 66.5 0.4 2.5e-18 65.5 0.4 1.6 1 0 0 1 1 1 1 GYF domain Homeodomain PF00046.29 KXG48001.1 - 3.3 7.6 5.6 1.4 8.8 2.6 2.0 2 0 0 2 2 2 0 Homeodomain CTNNB1_binding PF08347.11 KXG48002.1 - 0.1 12.8 1.8 0.11 12.6 0.7 1.6 1 1 1 2 2 2 0 N-terminal CTNNB1 binding ADH_zinc_N PF00107.26 KXG48003.1 - 6.9e-23 81.1 0.6 1.3e-22 80.1 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG48003.1 - 4e-11 44.1 0.0 1.1e-10 42.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG48003.1 - 0.0042 17.0 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXG48003.1 - 0.016 14.6 0.4 0.04 13.4 0.3 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Trp_syntA PF00290.20 KXG48005.1 - 2.8e-95 318.1 0.0 5.5e-95 317.1 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KXG48005.1 - 1.9e-51 175.3 1.7 3e-51 174.6 1.7 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ATP-synt_ab PF00006.25 KXG48006.1 - 7.6e-69 231.6 0.0 1e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KXG48006.1 - 2e-11 44.2 0.2 4e-11 43.3 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Usp PF00582.26 KXG48007.1 - 2.6e-21 76.6 1.8 1.4e-19 71.0 1.8 2.7 1 1 0 1 1 1 1 Universal stress protein family DnaJ PF00226.31 KXG48008.1 - 2e-19 69.5 0.3 2e-19 69.5 0.3 2.0 2 0 0 2 2 2 1 DnaJ domain zf-C4H2 PF10146.9 KXG48008.1 - 0.0051 17.1 4.5 0.0051 17.1 4.5 1.5 2 0 0 2 2 2 1 Zinc finger-containing protein DUF4200 PF13863.6 KXG48008.1 - 0.028 14.8 10.5 0.028 14.8 10.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) IDEAL PF08858.10 KXG48008.1 - 0.035 13.8 0.0 0.14 11.9 0.0 2.1 1 0 0 1 1 1 0 IDEAL domain RR_TM4-6 PF06459.12 KXG48008.1 - 5.2 6.8 12.0 0.19 11.5 5.5 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Inv-AAD PF18785.1 KXG48009.1 - 9.7e-46 154.8 0.0 1.3e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KXG48009.1 - 1.4e-11 44.2 0.0 5.3e-11 42.3 0.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 KXG48009.1 - 2.7e-05 24.1 0.0 5.5e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Stn1 PF10451.9 KXG48010.1 - 3.1e-11 42.7 0.1 3.2e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 KXG48010.1 - 0.013 15.5 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Mitofilin PF09731.9 KXG48010.1 - 1.7 7.4 8.6 2.4 6.9 8.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Stc1 PF12898.7 KXG48012.1 - 9.6e-15 54.9 13.1 1.6e-14 54.2 13.1 1.4 1 0 0 1 1 1 1 Stc1 domain Pkinase PF00069.25 KXG48013.1 - 2.8e-57 194.1 0.0 4.3e-57 193.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48013.1 - 1e-30 106.9 0.0 5.7e-29 101.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KXG48013.1 - 0.0015 17.6 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KXG48013.1 - 0.097 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RNase_PH PF01138.21 KXG48014.1 - 2.5e-12 47.4 0.0 6.4e-12 46.1 0.0 1.7 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXG48014.1 - 0.01 15.8 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Fmp27 PF10344.9 KXG48015.1 - 0.0056 14.8 0.0 0.0077 14.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Cytochrom_C PF00034.21 KXG48016.1 - 6.3e-13 49.7 0.1 1.1e-12 48.9 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KXG48016.1 - 4.4e-07 30.1 2.7 2.4e-06 27.8 2.7 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KXG48016.1 - 0.00035 20.3 0.1 0.00077 19.2 0.0 1.6 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 KXG48016.1 - 0.068 12.7 0.1 0.078 12.6 0.1 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Haem_bd PF14376.6 KXG48016.1 - 0.62 10.0 2.1 0.69 9.9 0.2 2.0 2 1 0 2 2 2 0 Haem-binding domain Baculo_PEP_C PF04513.12 KXG48017.1 - 0.29 11.2 2.4 0.67 10.0 0.2 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dala_Dala_lig_C PF07478.13 KXG48019.1 - 7.4e-12 45.2 0.0 1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KXG48019.1 - 0.00021 21.4 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KXG48019.1 - 0.0011 18.8 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 KXG48019.1 - 0.0043 16.6 0.0 0.0078 15.7 0.0 1.5 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 KXG48019.1 - 0.0048 16.5 0.1 0.021 14.4 0.1 2.0 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 KXG48019.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain ATE_C PF04377.15 KXG48020.1 - 2.3e-47 161.0 1.6 3.8e-47 160.3 1.6 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KXG48020.1 - 2.2e-19 69.6 0.3 5.3e-19 68.4 0.3 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 KXG48020.1 - 0.01 16.0 0.3 0.018 15.2 0.3 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NUDIX PF00293.28 KXG48021.1 - 1.4e-18 67.2 0.4 1.7e-18 67.0 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain RNA_pol_A_bac PF01000.26 KXG48022.1 - 7.8e-31 106.8 0.0 1.2e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KXG48022.1 - 7.8e-14 50.9 0.0 1.1e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain adh_short_C2 PF13561.6 KXG48023.1 - 3.8e-46 157.6 0.0 4.7e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG48023.1 - 1.3e-31 109.6 0.0 1.6e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Aa_trans PF01490.18 KXG48024.1 - 5.4e-24 84.7 24.5 8.5e-24 84.0 24.5 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KXG48024.1 - 1.1e-05 24.6 10.6 1.1e-05 24.6 10.6 2.8 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Pro_dh PF01619.18 KXG48025.1 - 2.3e-52 178.4 0.0 4.5e-52 177.4 0.0 1.4 1 1 0 1 1 1 1 Proline dehydrogenase P5CR_dimer PF14748.6 KXG48026.1 - 9.1e-22 77.3 0.2 2.2e-21 76.1 0.1 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KXG48026.1 - 1.2e-09 38.6 0.0 2.4e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KXG48026.1 - 0.0001 22.0 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 KXG48026.1 - 0.11 12.0 0.0 0.67 9.5 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Aldedh PF00171.22 KXG48027.1 - 2.1e-79 267.2 0.0 1.9e-73 247.5 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Cupin_2 PF07883.11 KXG48028.1 - 6.1e-08 32.3 0.2 0.00023 20.8 0.0 2.5 2 1 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 KXG48028.1 - 2.7e-07 30.3 0.0 4.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Cupin FMO-like PF00743.19 KXG48029.1 - 1.6e-13 49.9 1.3 2.4e-13 49.3 0.1 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXG48029.1 - 4.8e-10 39.5 0.1 2.6e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXG48029.1 - 5.2e-06 25.8 0.2 6.3e-05 22.3 0.1 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXG48029.1 - 8.2e-06 25.9 0.1 0.0087 16.1 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 KXG48029.1 - 0.00017 21.3 0.8 0.32 10.5 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXG48029.1 - 0.0011 18.3 0.1 0.025 13.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG48029.1 - 0.0041 16.4 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KXG48029.1 - 0.26 10.0 1.1 0.53 8.9 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Fungal_trans PF04082.18 KXG48030.1 - 8e-14 51.3 1.3 1.3e-13 50.6 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain VD10_N PF08476.10 KXG48030.1 - 0.049 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Viral D10 N-terminal Calcipressin PF04847.12 KXG48031.1 - 3e-31 108.6 0.5 3.8e-31 108.3 0.5 1.1 1 0 0 1 1 1 1 Calcipressin Phage_cap_P2 PF05125.12 KXG48031.1 - 0.19 10.7 0.1 0.29 10.1 0.1 1.2 1 0 0 1 1 1 0 Phage major capsid protein, P2 family FAD_binding_3 PF01494.19 KXG48032.1 - 1.4e-09 37.6 1.4 8.3e-09 35.1 1.4 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXG48032.1 - 0.00028 21.0 0.1 0.0027 17.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXG48032.1 - 0.001 18.7 2.4 0.029 14.0 0.2 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG48032.1 - 0.054 12.7 0.0 0.095 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MerR-DNA-bind PF09278.11 KXG48032.1 - 0.095 13.2 0.1 0.27 11.8 0.1 1.8 1 0 0 1 1 1 0 MerR, DNA binding Pyr_redox PF00070.27 KXG48032.1 - 0.12 12.9 0.1 1.5 9.4 0.0 2.8 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KXG48032.1 - 0.23 10.2 0.1 0.38 9.5 0.1 1.3 1 0 0 1 1 1 0 MCRA family AA_permease_2 PF13520.6 KXG48033.1 - 1.6e-58 198.6 23.0 7.9e-57 193.0 13.7 2.1 1 1 1 2 2 2 2 Amino acid permease ADH_zinc_N PF00107.26 KXG48035.1 - 1.7e-17 63.6 0.0 3.1e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG48035.1 - 6.9e-12 46.6 0.0 1.4e-11 45.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG48035.1 - 1e-08 35.0 0.0 1.1e-07 31.7 0.0 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GrpE PF01025.19 KXG48036.1 - 3.5e-39 134.1 4.2 5.4e-39 133.5 4.2 1.2 1 0 0 1 1 1 1 GrpE Peptidase_S49 PF01343.18 KXG48036.1 - 0.033 14.1 0.7 0.051 13.5 0.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 HisK_N PF09385.10 KXG48036.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.4 1 1 0 1 1 1 0 Histidine kinase N terminal tRNA-synt_2d PF01409.20 KXG48037.1 - 4.9e-48 163.8 0.3 4.5e-25 88.5 0.0 2.3 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KXG48037.1 - 6.8e-28 96.9 0.0 2.2e-27 95.3 0.0 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.27 KXG48038.1 - 8.4e-38 128.2 0.4 2.6e-17 62.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein COX6B PF02297.17 KXG48039.1 - 2.4e-18 66.1 7.6 2.8e-18 65.9 7.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.14 KXG48039.1 - 0.0088 16.0 0.5 0.012 15.6 0.5 1.2 1 0 0 1 1 1 1 APOBEC-like C-terminal domain B12D PF06522.11 KXG48040.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.22 KXG48041.1 - 8.1e-18 64.0 0.2 4.3e-17 61.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXG48041.1 - 0.0023 18.0 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 KXG48041.1 - 0.034 14.2 0.0 0.076 13.1 0.0 1.7 1 0 0 1 1 1 0 Limkain b1 DUF2934 PF11154.8 KXG48041.1 - 0.12 12.1 1.5 0.24 11.1 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) SRA1 PF07304.11 KXG48042.1 - 1e-13 51.3 0.0 1e-13 51.3 0.0 3.5 4 1 0 4 4 4 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 KXG48042.1 - 1.5e-10 41.5 5.7 0.87 10.6 0.1 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Sec16_C PF12931.7 KXG48042.1 - 0.0019 17.9 0.1 0.019 14.6 0.1 2.4 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 ANAPC4_WD40 PF12894.7 KXG48042.1 - 0.0021 18.3 0.4 0.048 14.0 0.1 3.3 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Pex14_N PF04695.13 KXG48043.1 - 1.7e-44 152.2 3.7 1.7e-44 152.2 3.7 2.6 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PAPA-1 PF04795.12 KXG48044.1 - 2.7e-31 108.2 5.3 2.7e-31 108.2 5.3 3.2 3 0 0 3 3 3 1 PAPA-1-like conserved region MctB PF11382.8 KXG48045.1 - 0.025 14.3 0.0 0.029 14.1 0.0 1.0 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Mus7 PF09462.10 KXG48046.1 - 5.6e-203 676.2 0.0 7.6e-203 675.8 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family Glyco_hydro_71 PF03659.14 KXG48047.1 - 4.8e-129 430.4 5.6 6.5e-129 430.0 5.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 FMO-like PF00743.19 KXG48047.1 - 1.9e-19 69.5 0.0 2.1e-09 36.4 0.0 2.4 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXG48047.1 - 1.6e-07 30.9 0.0 5.6e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG48047.1 - 8.4e-07 28.5 0.0 8.2e-05 22.0 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG48047.1 - 4.2e-05 22.9 0.1 0.00066 18.9 0.0 2.4 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DUF4402 PF14352.6 KXG48047.1 - 0.12 13.1 1.1 0.23 12.1 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) DUF4050 PF13259.6 KXG48048.1 - 1.5e-52 178.6 11.1 4.1e-52 177.2 11.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) N-SET PF11764.8 KXG48048.1 - 1.2 9.3 5.3 2.7 8.1 4.7 2.0 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N AAA PF00004.29 KXG48049.1 - 1.8e-40 138.5 0.0 2.6e-37 128.2 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXG48049.1 - 1.4e-08 34.4 0.1 3.6e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KXG48049.1 - 2.4e-05 24.8 0.2 0.0011 19.3 0.0 3.4 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KXG48049.1 - 0.00012 21.8 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KXG48049.1 - 0.0003 20.1 0.0 0.00069 18.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KXG48049.1 - 0.00038 20.8 0.9 0.021 15.1 0.1 3.2 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 KXG48049.1 - 0.0011 18.9 0.0 0.004 17.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXG48049.1 - 0.0012 19.0 0.0 0.0054 16.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 KXG48049.1 - 0.0048 17.3 0.1 0.13 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXG48049.1 - 0.0083 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 KXG48049.1 - 0.02 15.2 0.1 0.048 13.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXG48049.1 - 0.021 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KXG48049.1 - 0.031 14.7 0.0 0.09 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KXG48049.1 - 0.047 13.7 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KXG48049.1 - 0.047 13.1 1.0 1.4 8.3 0.2 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.6 KXG48049.1 - 0.068 13.7 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXG48049.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain HTH_ABP1_N PF18107.1 KXG48049.1 - 0.13 12.0 2.8 0.77 9.5 2.3 2.5 2 1 0 2 2 2 0 Fission yeast centromere protein N-terminal domain TsaE PF02367.17 KXG48049.1 - 0.14 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE LIM_bind PF01803.16 KXG48050.1 - 5.3e-70 235.7 0.1 5.3e-70 235.7 0.1 4.5 2 1 1 3 3 3 1 LIM-domain binding protein cobW PF02492.19 KXG48051.1 - 5.2e-33 114.1 0.0 6.4e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KXG48051.1 - 1.7e-05 24.0 1.3 0.00019 20.5 1.3 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KXG48051.1 - 0.0039 17.6 0.0 0.0054 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KXG48051.1 - 0.0062 16.5 0.0 0.0092 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KXG48051.1 - 0.018 14.9 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 KXG48051.1 - 0.019 15.0 0.0 0.049 13.7 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase CbiA PF01656.23 KXG48051.1 - 0.043 13.9 0.0 0.097 12.7 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KXG48051.1 - 0.045 14.3 0.0 0.068 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 KXG48051.1 - 0.046 13.5 0.0 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 KXG48051.1 - 0.053 13.4 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 KXG48051.1 - 0.099 12.6 0.0 0.15 12.0 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 KXG48051.1 - 0.12 12.0 0.1 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KXG48051.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain BING4CT PF08149.11 KXG48052.1 - 1.7e-38 130.2 0.0 3.6e-35 119.6 0.0 2.7 2 0 0 2 2 2 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KXG48052.1 - 1.9e-08 34.5 0.2 0.76 10.1 0.0 5.7 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXG48052.1 - 0.00021 22.0 0.1 0.35 11.8 0.0 4.2 4 1 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KXG48052.1 - 0.003 16.7 0.0 0.0074 15.4 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region HNF_C PF09354.10 KXG48052.1 - 0.048 14.7 0.0 0.12 13.4 0.0 1.6 1 0 0 1 1 1 0 HNF3 C-terminal domain TTRAP PF14203.6 KXG48052.1 - 0.068 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein RIBIOP_C PF04950.12 KXG48053.1 - 8e-105 350.4 0.0 1.5e-104 349.6 0.0 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KXG48053.1 - 3.1e-21 75.2 0.0 8.2e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain SNAP PF14938.6 KXG48054.1 - 1.2e-114 382.6 10.6 1.3e-114 382.4 10.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KXG48054.1 - 5.5e-05 23.4 13.7 0.026 14.8 0.9 4.4 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXG48054.1 - 0.0024 17.6 19.1 0.21 11.5 0.4 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXG48054.1 - 0.0033 17.4 10.4 0.44 10.7 0.3 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXG48054.1 - 0.013 16.1 12.5 0.66 10.7 0.8 5.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXG48054.1 - 0.013 15.7 16.9 0.041 14.1 0.4 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2811 PF10929.8 KXG48054.1 - 0.015 15.5 0.3 0.043 14.1 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) Spatacsin_C PF14649.6 KXG48054.1 - 0.022 13.9 9.1 4.2 6.4 7.1 3.0 1 1 1 2 2 2 0 Spatacsin C-terminus PhoU PF01895.19 KXG48054.1 - 0.03 14.8 2.8 7.7 7.1 0.2 3.1 2 1 1 3 3 2 0 PhoU domain Hep_59 PF07052.11 KXG48054.1 - 0.046 14.5 1.0 0.1 13.3 1.0 1.6 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 DUF5344 PF17279.2 KXG48054.1 - 0.055 14.1 1.6 2.6 8.7 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5344) TPR_14 PF13428.6 KXG48054.1 - 0.078 13.8 11.9 2.5 9.1 1.6 5.0 2 1 3 5 5 5 0 Tetratricopeptide repeat NSF PF02071.20 KXG48054.1 - 0.097 13.4 17.6 1.2 10.2 0.6 7.0 7 0 0 7 7 6 0 Aromatic-di-Alanine (AdAR) repeat MIT PF04212.18 KXG48054.1 - 0.2 11.7 15.5 3.8 7.7 0.7 4.3 2 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 KXG48054.1 - 0.76 10.0 24.2 1.3 9.3 0.8 7.1 4 3 3 8 8 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXG48054.1 - 0.97 9.4 6.2 5.6 7.0 0.0 4.0 3 1 2 5 5 5 0 Tetratricopeptide repeat Glu-tRNAGln PF02686.15 KXG48055.1 - 1.3e-11 44.6 0.2 7.1e-11 42.2 0.2 2.0 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF726 PF05277.12 KXG48056.1 - 5e-124 413.7 0.7 6.5e-124 413.3 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 KXG48056.1 - 3.8e-05 23.9 0.1 0.00026 21.2 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Cutinase PF01083.22 KXG48056.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Cutinase EFTUD2 PF16004.5 KXG48056.1 - 7.7 7.1 9.3 0.39 11.3 0.2 2.6 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus ADH_zinc_N_2 PF13602.6 KXG48057.1 - 2.5e-27 96.5 0.1 4.1e-27 95.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXG48057.1 - 3.4e-15 56.2 0.0 5.7e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG48057.1 - 4.7e-05 23.2 0.2 0.0012 18.7 0.0 2.4 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Fe_hyd_lg_C PF02906.14 KXG48057.1 - 0.03 14.0 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Peptidase_M20 PF01546.28 KXG48058.1 - 2.6e-26 92.6 0.1 3.8e-26 92.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXG48058.1 - 3.3e-12 46.3 0.0 8.2e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF3995 PF13160.6 KXG48058.1 - 0.16 12.4 1.4 0.35 11.2 0.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3995) 2OG-FeII_Oxy PF03171.20 KXG48060.1 - 3.9e-15 56.2 0.0 6.9e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXG48060.1 - 7.7e-14 52.5 0.0 2.3e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.16 KXG48061.1 - 2.3e-28 99.2 31.7 2.3e-28 99.2 31.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 KXG48061.1 - 0.018 14.9 1.3 0.038 13.8 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Hexapep PF00132.24 KXG48062.1 - 1.1e-08 34.4 3.1 0.002 17.7 1.2 2.6 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KXG48062.1 - 0.00046 19.2 1.1 0.0009 18.3 1.1 1.4 1 1 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 KXG48062.1 - 0.0013 19.2 0.0 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_hydro_114 PF03537.13 KXG48063.1 - 3.4e-82 275.2 1.1 2.2e-79 266.0 0.1 2.3 2 1 0 2 2 2 2 Glycoside-hydrolase family GH114 PfaD_N PF18328.1 KXG48063.1 - 0.05 13.5 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Fatty acid synthase subunit PfaD N-terminal domain RNA_pol_Rpb1_1 PF04997.12 KXG48063.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Glyco_hydro_75 PF07335.11 KXG48064.1 - 1.7e-44 152.0 0.2 2.4e-44 151.5 0.2 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 EB PF01683.18 KXG48064.1 - 4.9 7.5 10.1 1.7 9.0 6.6 1.9 2 0 0 2 2 2 0 EB module NPV_P10 PF05531.12 KXG48065.1 - 8.2 7.0 17.1 2 9.0 0.0 5.8 4 2 3 7 7 7 0 Nucleopolyhedrovirus P10 protein ParD_antitoxin PF03693.14 KXG48065.1 - 9.8 6.7 7.2 9.9 6.7 0.6 3.5 3 0 0 3 3 3 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Pkinase PF00069.25 KXG48066.1 - 2.5e-63 213.9 0.0 3.4e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48066.1 - 2.4e-33 115.5 0.0 3.3e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG48066.1 - 2.8e-07 30.2 0.0 4.4e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXG48066.1 - 0.0011 18.9 0.9 0.0035 17.3 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXG48066.1 - 0.0029 17.0 0.1 0.0054 16.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXG48066.1 - 0.018 13.9 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KXG48066.1 - 0.021 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Cellulase PF00150.18 KXG48067.1 - 1.3e-13 51.1 1.0 1.3e-13 51.1 1.0 1.8 1 1 1 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Radical_SAM PF04055.21 KXG48067.1 - 0.085 13.2 0.0 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Radical SAM superfamily HATPase_c PF02518.26 KXG48068.1 - 1.6e-16 60.8 0.0 3.9e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXG48068.1 - 6.1e-12 45.7 0.0 1.7e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXG48068.1 - 6.2e-12 45.4 0.9 6.2e-12 45.4 0.9 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PHY PF00360.20 KXG48068.1 - 3.8e-07 29.6 0.0 1.4e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Phytochrome region PAS_2 PF08446.11 KXG48068.1 - 0.0024 18.5 0.0 0.0078 16.9 0.0 1.9 1 0 0 1 1 1 1 PAS fold GAF PF01590.26 KXG48068.1 - 0.081 13.6 0.0 0.28 11.8 0.0 1.9 1 0 0 1 1 1 0 GAF domain HATPase_c_5 PF14501.6 KXG48068.1 - 0.11 12.5 0.0 0.72 9.8 0.0 2.4 1 1 0 1 1 1 0 GHKL domain SNF2_N PF00176.23 KXG48069.1 - 3.7e-68 229.8 0.1 2.6e-66 223.7 0.1 2.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXG48069.1 - 7e-16 58.6 0.0 2.1e-15 57.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG48069.1 - 5.8e-08 32.9 0.0 5.8e-08 32.9 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 KXG48069.1 - 0.0085 15.0 0.3 2.3 7.0 0.1 2.2 2 0 0 2 2 2 2 P-loop containing NTP hydrolase pore-1 SDA1 PF05285.12 KXG48069.1 - 0.058 12.8 34.2 0.21 11.0 16.9 2.5 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 KXG48069.1 - 3 7.1 48.0 0.019 14.3 17.4 2.8 3 0 0 3 3 3 0 BUD22 TPP_enzyme_N PF02776.18 KXG48070.1 - 1.5e-41 141.9 0.3 4.9e-41 140.2 0.1 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXG48070.1 - 4e-22 78.6 0.3 3.8e-21 75.5 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXG48070.1 - 5.2e-09 36.0 0.0 1.2e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Peptidase_S78_2 PF14550.6 KXG48070.1 - 0.058 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative phage serine protease XkdF XFP_N PF09364.10 KXG48070.1 - 0.18 10.6 0.4 0.28 9.9 0.4 1.2 1 0 0 1 1 1 0 XFP N-terminal domain SIR2 PF02146.17 KXG48071.1 - 2.7e-39 134.9 0.0 9e-39 133.2 0.0 1.7 1 1 0 1 1 1 1 Sir2 family APG12 PF04110.13 KXG48073.1 - 3.7e-29 101.0 0.0 6.9e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KXG48073.1 - 0.0052 17.0 0.0 0.0069 16.6 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.15 KXG48074.1 - 5e-108 360.4 1.5 6e-108 360.1 1.5 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KXG48074.1 - 1e-05 25.2 0.3 1.7e-05 24.4 0.3 1.5 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 KXG48074.1 - 0.00045 19.3 0.0 0.00067 18.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4861) Dfp1_Him1_M PF08630.10 KXG48075.1 - 3e-40 137.3 0.0 8.9e-40 135.8 0.0 1.9 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 KXG48075.1 - 8.6e-21 73.8 0.1 1.6e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 KXG48075.1 - 0.027 14.4 0.0 0.085 12.8 0.0 1.9 1 0 0 1 1 1 0 twin BRCT domain Peptidase_M24 PF00557.24 KXG48076.1 - 1.9e-49 168.2 0.0 2.9e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXG48076.1 - 6.8e-37 125.9 0.0 1.2e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RuBisCO_large PF00016.20 KXG48076.1 - 0.043 13.0 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Creatinase_N PF01321.18 KXG48076.1 - 0.12 13.1 0.0 1 10.0 0.0 2.3 1 1 0 1 1 1 0 Creatinase/Prolidase N-terminal domain Pyridox_ox_2 PF12900.7 KXG48077.1 - 1.1e-36 125.9 0.0 1.5e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ank_2 PF12796.7 KXG48078.1 - 1.9e-37 127.7 2.8 8.5e-13 48.7 0.0 8.6 7 1 1 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG48078.1 - 6.1e-30 103.2 7.0 5.4e-05 23.7 0.0 11.8 11 2 1 12 12 12 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG48078.1 - 3.6e-26 88.4 13.5 0.0081 16.6 0.0 12.3 12 0 0 12 12 12 5 Ankyrin repeat Ank_5 PF13857.6 KXG48078.1 - 1.8e-21 75.9 10.1 0.013 15.8 0.0 10.9 12 1 0 13 13 13 5 Ankyrin repeats (many copies) Ank PF00023.30 KXG48078.1 - 1.9e-15 56.5 23.0 0.00029 21.1 0.0 9.3 12 0 0 12 12 12 5 Ankyrin repeat RIBIOP_C PF04950.12 KXG48078.1 - 0.005 16.3 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Pes-10 PF07149.11 KXG48078.1 - 0.16 11.0 4.8 0.076 12.1 2.1 1.8 2 0 0 2 2 2 0 Pes-10 UQ_con PF00179.26 KXG48079.1 - 1.8e-36 124.9 0.2 2.2e-36 124.6 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXG48079.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain LAMTOR PF15454.6 KXG48080.1 - 4e-19 69.0 0.1 6.5e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator SVIP PF15811.5 KXG48080.1 - 0.13 12.7 1.3 0.35 11.4 0.1 2.1 2 0 0 2 2 2 0 Small VCP/p97-interacting protein DUF2011 PF09428.10 KXG48081.1 - 7.7e-33 112.6 0.8 1.5e-31 108.5 0.0 2.3 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) Tht1 PF04163.12 KXG48083.1 - 0.00035 19.5 11.8 0.00035 19.5 11.8 2.1 2 1 0 2 2 2 1 Tht1-like nuclear fusion protein Baculo_PEP_C PF04513.12 KXG48083.1 - 0.0013 18.7 3.6 0.0013 18.7 3.6 2.4 1 1 2 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus FH2 PF02181.23 KXG48083.1 - 0.02 14.0 11.8 0.082 12.0 7.7 2.3 1 1 0 2 2 2 0 Formin Homology 2 Domain ROS_MUCR PF05443.11 KXG48083.1 - 0.13 12.3 0.2 0.13 12.3 0.2 3.2 2 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein DUF1664 PF07889.12 KXG48083.1 - 0.51 10.4 14.6 0.15 12.1 6.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KXG48083.1 - 3.7 7.7 19.9 15 5.8 0.1 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family RNA_polI_A14 PF08203.11 KXG48083.1 - 8.4 7.2 8.2 2.7 8.8 3.8 2.5 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Ribosomal_L6 PF00347.23 KXG48084.1 - 9.1e-25 87.1 0.0 6.4e-11 42.8 0.0 3.0 2 2 0 2 2 2 2 Ribosomal protein L6 Inositol_P PF00459.25 KXG48085.1 - 1.4e-50 172.3 0.2 2.3e-50 171.6 0.2 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family VHS PF00790.19 KXG48086.1 - 6.8e-25 87.6 0.0 1.5e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 VHS domain ENTH PF01417.20 KXG48086.1 - 0.00035 20.6 0.0 0.00086 19.3 0.0 1.6 1 0 0 1 1 1 1 ENTH domain GAT PF03127.14 KXG48086.1 - 0.00094 19.4 0.0 0.0024 18.1 0.0 1.8 1 1 0 1 1 1 1 GAT domain Elongin_A PF06881.11 KXG48086.1 - 0.083 13.4 0.0 0.27 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Dexa_ind PF15198.6 KXG48086.1 - 0.19 11.9 0.2 6 7.0 0.1 2.2 2 0 0 2 2 2 0 Dexamethasone-induced ABM PF03992.16 KXG48087.1 - 0.00069 19.7 0.3 0.1 12.7 0.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF4107 PF13389.6 KXG48087.1 - 0.073 13.2 0.0 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) Hydrolase_4 PF12146.8 KXG48088.1 - 0.00024 20.4 0.1 0.0052 16.1 0.1 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXG48088.1 - 0.00046 20.9 0.0 0.00085 20.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KXG48088.1 - 0.00048 20.0 0.1 0.00078 19.3 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 KXG48088.1 - 0.0005 19.6 0.0 0.00073 19.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 KXG48088.1 - 0.0017 18.1 0.1 0.43 10.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KXG48088.1 - 0.0048 16.7 0.0 3.7 7.3 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase YdjM PF04307.14 KXG48088.1 - 0.012 14.9 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase LIDHydrolase PF10230.9 KXG48088.1 - 0.041 13.5 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Cutinase PF01083.22 KXG48088.1 - 0.19 11.7 0.1 0.33 10.9 0.1 1.3 1 0 0 1 1 1 0 Cutinase Flavoprotein PF02441.19 KXG48089.1 - 9e-14 51.5 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein MFS_1 PF07690.16 KXG48090.1 - 3.4e-42 144.6 45.0 3.4e-42 144.6 45.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG48090.1 - 3.9e-17 62.2 13.0 3.9e-17 62.2 13.0 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KXG48090.1 - 1.4 7.1 9.0 0.062 11.6 1.5 2.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Amidase PF01425.21 KXG48092.1 - 1e-100 337.8 0.0 2.1e-100 336.8 0.0 1.5 1 1 0 1 1 1 1 Amidase Cas_NE0113 PF09623.10 KXG48092.1 - 0.06 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) Abhydrolase_3 PF07859.13 KXG48093.1 - 5.7e-36 124.4 0.0 7e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KXG48093.1 - 2.3e-08 33.9 0.0 0.00023 20.8 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KXG48093.1 - 1.7e-05 24.4 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KXG48093.1 - 0.17 11.4 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Tannase PF07519.11 KXG48094.1 - 4.4e-122 408.4 1.2 5.2e-122 408.1 1.2 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KXG48094.1 - 0.00073 18.9 0.0 0.015 14.6 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXG48094.1 - 0.0021 17.6 0.4 0.014 14.8 0.4 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family BDM PF10684.9 KXG48094.1 - 0.027 14.8 0.0 0.061 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative biofilm-dependent modulation protein Abhydrolase_1 PF00561.20 KXG48094.1 - 0.087 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold NolX PF05819.11 KXG48094.1 - 0.25 10.6 0.0 0.41 9.9 0.0 1.2 1 0 0 1 1 1 0 NolX protein MFS_1 PF07690.16 KXG48096.1 - 5.6e-16 58.4 53.2 1.5e-15 57.0 51.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MiAMP1 PF09117.10 KXG48096.1 - 0.14 12.4 0.1 13 6.1 0.0 2.4 2 0 0 2 2 2 0 MiAMP1 DUF3043 PF11241.8 KXG48096.1 - 1.8 8.6 3.8 1.4 8.9 2.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) DAO PF01266.24 KXG48097.1 - 6.3e-29 101.7 0.1 7.5e-29 101.4 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXG48097.1 - 0.0013 19.2 1.4 0.0041 17.6 0.9 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG48097.1 - 0.012 14.9 0.2 0.029 13.6 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG48097.1 - 0.048 12.7 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 KXG48097.1 - 0.051 12.8 0.3 0.093 12.0 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KXG48097.1 - 0.19 11.6 0.3 0.3 10.9 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KXG48097.1 - 0.21 10.8 0.2 0.34 10.1 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG48097.1 - 0.23 11.7 1.4 0.42 10.9 0.2 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PTR2 PF00854.21 KXG48098.1 - 2e-75 254.1 9.7 2.9e-75 253.6 9.7 1.2 1 0 0 1 1 1 1 POT family DUF1435 PF07256.12 KXG48098.1 - 0.059 13.5 0.2 0.19 11.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1435) Abhydrolase_3 PF07859.13 KXG48099.1 - 1.2e-54 185.4 0.0 1.5e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXG48099.1 - 5.4e-06 25.5 0.1 1.3e-05 24.3 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KXG48099.1 - 0.00013 21.6 0.0 0.009 15.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase_phd PF10503.9 KXG48099.1 - 0.025 14.0 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Gpi16 PF04113.14 KXG48100.1 - 1.3e-244 812.8 0.0 1.7e-244 812.5 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.15 KXG48101.1 - 2.2e-73 247.0 1.5 2.6e-73 246.8 1.5 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.21 KXG48101.1 - 0.011 15.6 0.2 0.016 15.0 0.2 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.6 KXG48101.1 - 0.011 16.1 3.2 0.027 14.8 3.2 1.6 1 0 0 1 1 1 0 Syntaxin-like protein ApoLp-III PF07464.11 KXG48101.1 - 0.028 14.5 0.4 0.051 13.7 0.4 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Glutaredoxin2_C PF04399.13 KXG48101.1 - 0.037 13.9 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DegS PF05384.11 KXG48101.1 - 0.049 13.1 1.6 0.59 9.6 0.2 2.3 1 1 1 2 2 2 0 Sensor protein DegS TPR_MLP1_2 PF07926.12 KXG48101.1 - 0.064 13.3 1.9 0.11 12.5 1.9 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein GIT1_C PF12205.8 KXG48101.1 - 0.16 12.0 0.4 0.38 10.9 0.2 1.7 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Occludin_ELL PF07303.13 KXG48101.1 - 0.5 11.1 2.8 6.5 7.5 0.1 2.8 2 1 1 3 3 2 0 Occludin homology domain XhlA PF10779.9 KXG48101.1 - 5 7.4 5.3 3.1 8.1 0.8 2.3 2 0 0 2 2 2 0 Haemolysin XhlA SPOC PF07744.13 KXG48102.1 - 4e-25 88.5 0.0 7.8e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KXG48102.1 - 3.9e-24 85.3 0.9 3.9e-24 85.3 0.9 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KXG48102.1 - 1.4e-10 40.9 13.1 2.4e-10 40.1 13.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 KXG48102.1 - 0.019 15.3 0.4 0.019 15.3 0.4 2.4 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.6 KXG48102.1 - 0.062 12.9 5.6 0.11 12.1 5.6 1.4 1 0 0 1 1 1 0 PHD-finger MPLKIP PF15502.6 KXG48102.1 - 0.32 11.2 1.9 1.4 9.2 1.9 2.2 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein CEBP_ZZ PF16366.5 KXG48102.1 - 0.52 10.6 4.6 1 9.6 4.6 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Terminase_GpA PF05876.12 KXG48102.1 - 1.7 7.1 5.8 2.5 6.6 5.8 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zinc_ribbon_10 PF10058.9 KXG48102.1 - 1.9 8.3 7.7 4.9 7.0 6.7 2.3 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF573 PF04504.14 KXG48103.1 - 0.036 14.7 0.6 0.092 13.4 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Arabinose_trans PF04602.12 KXG48103.1 - 0.048 12.5 0.5 0.063 12.1 0.5 1.1 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein CENP-Q PF13094.6 KXG48103.1 - 0.61 10.3 13.8 1.5 9.0 13.8 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FF PF01846.19 KXG48104.1 - 2.7e-12 46.7 5.6 4.9e-10 39.4 0.2 3.3 3 0 0 3 3 3 2 FF domain WW PF00397.26 KXG48104.1 - 3.8e-10 39.7 4.8 1.4e-08 34.7 2.3 3.0 2 0 0 2 2 2 2 WW domain VGLL4 PF15245.6 KXG48104.1 - 0.032 14.3 0.3 0.076 13.1 0.3 1.6 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Proteasome PF00227.26 KXG48105.1 - 1.4e-61 207.3 0.2 1.7e-61 207.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXG48105.1 - 2.9e-13 49.2 0.1 8.9e-13 47.7 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 KXG48105.1 - 0.016 15.3 0.4 0.049 13.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 KXG48105.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Con-6 PF10346.9 KXG48107.1 - 9.4e-26 89.5 2.6 1.4e-14 53.8 0.3 3.0 3 0 0 3 3 3 2 Conidiation protein 6 HIM1 PF08732.10 KXG48107.1 - 2.5e-08 33.7 0.0 3.8e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 HIM1 Epimerase PF01370.21 KXG48107.1 - 2.9e-06 26.9 0.0 8.5e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXG48107.1 - 7.4e-06 26.0 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KXG48107.1 - 0.00041 20.8 0.2 0.0037 17.7 0.0 2.2 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KXG48107.1 - 0.0026 17.3 1.3 0.013 15.1 1.3 1.9 1 1 0 1 1 1 1 NmrA-like family DUF1471 PF07338.13 KXG48107.1 - 0.025 14.5 0.6 0.054 13.5 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) TraC PF07820.12 KXG48107.1 - 0.076 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 TraC-like protein NAD_binding_4 PF07993.12 KXG48107.1 - 0.16 11.1 0.1 3.4 6.8 0.0 2.3 2 1 0 2 2 2 0 Male sterility protein adh_short PF00106.25 KXG48108.1 - 1.7e-06 27.6 0.0 3.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG48108.1 - 8.8e-06 25.4 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.17 KXG48108.1 - 0.0058 17.2 0.1 0.019 15.5 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 KXG48108.1 - 0.0094 15.8 0.5 0.013 15.4 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KXG48108.1 - 0.021 14.4 0.1 0.048 13.2 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family 3HCDH_N PF02737.18 KXG48108.1 - 0.026 14.4 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KXG48108.1 - 0.053 13.0 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KXG48108.1 - 0.053 12.9 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXG48108.1 - 0.083 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PS_Dcarbxylase PF02666.15 KXG48109.1 - 1.1e-55 188.4 0.1 1.4e-55 188.0 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Ank PF00023.30 KXG48110.1 - 1.1e-27 95.2 3.8 0.00067 20.0 0.0 7.7 6 2 2 8 8 8 6 Ankyrin repeat Ank_2 PF12796.7 KXG48110.1 - 8e-24 84.0 0.2 9.1e-08 32.6 0.0 5.2 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG48110.1 - 7.9e-22 77.3 0.6 2.8e-06 27.7 0.0 6.5 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG48110.1 - 2.9e-21 73.3 4.4 0.0066 16.9 0.0 8.8 9 1 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 KXG48110.1 - 9.8e-11 41.7 4.3 0.037 14.4 0.0 6.2 6 1 1 7 7 7 3 Ankyrin repeats (many copies) F-box-like PF12937.7 KXG48110.1 - 0.097 12.6 0.5 0.2 11.6 0.5 1.5 1 0 0 1 1 1 0 F-box-like Acyl-CoA_dh_1 PF00441.24 KXG48111.1 - 9.8e-33 113.5 0.8 1.6e-32 112.8 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXG48111.1 - 1.9e-23 82.5 0.1 3.2e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXG48111.1 - 7.8e-16 58.7 0.3 3.3e-15 56.7 0.0 2.2 2 2 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXG48111.1 - 1.3e-05 25.5 0.5 2.1e-05 24.8 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FAD_binding_1 PF00667.20 KXG48112.1 - 9.6e-62 208.4 0.0 1.7e-61 207.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain POR PF01558.18 KXG48112.1 - 7.6e-10 39.1 0.3 1.7e-09 38.0 0.3 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.21 KXG48112.1 - 2.8e-09 37.6 0.0 7.9e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 KXG48112.1 - 6.8e-06 26.3 0.1 1.7e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KXG48112.1 - 0.0011 18.8 0.3 0.0066 16.3 0.1 2.4 2 0 0 2 2 2 1 Transketolase, C-terminal domain FtsJ PF01728.19 KXG48113.1 - 2.6e-63 213.3 0.0 3.4e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.29 KXG48114.1 - 7e-45 152.9 0.2 1.4e-44 152.0 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG48114.1 - 9.4e-28 96.8 0.1 1.2e-26 93.2 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXG48114.1 - 0.01 16.1 0.3 0.037 14.3 0.3 2.0 1 1 0 1 1 1 0 AAA domain Zip PF02535.22 KXG48114.1 - 0.11 11.7 2.7 0.19 10.9 2.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIP PF07454.11 KXG48114.1 - 0.37 10.2 7.0 0.94 8.9 7.0 1.6 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) GCN5L1 PF06320.13 KXG48114.1 - 0.44 10.7 0.0 0.44 10.7 0.0 3.4 3 0 0 3 3 2 0 GCN5-like protein 1 (GCN5L1) Presenilin PF01080.17 KXG48114.1 - 0.44 9.3 10.4 0.85 8.3 10.4 1.5 1 0 0 1 1 1 0 Presenilin DUF2477 PF10631.9 KXG48114.1 - 0.68 10.6 2.3 2.7 8.7 2.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Neur_chan_memb PF02932.16 KXG48114.1 - 2.3 8.2 5.2 1 9.3 2.3 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region NPR3 PF03666.13 KXG48114.1 - 5.2 5.8 10.6 13 4.4 10.6 1.7 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 KXG48114.1 - 6.9 6.8 8.1 0.34 11.0 1.8 2.1 3 0 0 3 3 3 0 DDHD domain SAPS PF04499.15 KXG48114.1 - 9.7 4.8 9.7 23 3.6 9.7 1.6 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1688 PF07958.11 KXG48115.1 - 2.8e-164 546.8 0.0 3.1e-164 546.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) 4HBT PF03061.22 KXG48118.1 - 3e-08 33.9 0.0 6.4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DUF2717 PF10911.8 KXG48119.1 - 0.059 13.1 0.1 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2717) LAGLIDADG_3 PF14528.6 KXG48120.1 - 0.03 14.6 0.1 2.9 8.3 0.0 2.3 1 1 1 2 2 2 0 LAGLIDADG-like domain HECT PF00632.25 KXG48121.1 - 3.7e-76 256.5 0.0 5.8e-76 255.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.22 KXG48121.1 - 0.0033 17.6 0.7 0.21 11.9 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KXG48121.1 - 0.0079 16.7 0.1 0.16 12.5 0.0 2.9 2 0 0 2 2 2 1 HEAT-like repeat Arm PF00514.23 KXG48121.1 - 0.27 11.3 7.4 18 5.6 0.1 5.3 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 KXG48121.1 - 0.28 9.7 4.0 0.13 10.8 0.1 2.4 3 0 0 3 3 3 0 Adaptin N terminal region CTP_transf_like PF01467.26 KXG48122.1 - 2.2e-26 92.8 0.0 2.9e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like SIS PF01380.22 KXG48123.1 - 2.4e-13 50.1 0.0 2.4e-12 46.9 0.0 2.1 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.6 KXG48123.1 - 1.6e-06 28.2 0.1 0.00022 21.2 0.1 2.3 1 1 1 2 2 2 2 SIS domain Ubie_methyltran PF01209.18 KXG48124.1 - 4.8e-81 271.5 0.0 6.3e-81 271.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KXG48124.1 - 1.5e-16 60.9 0.0 3.9e-16 59.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG48124.1 - 8.4e-15 55.2 0.0 1.9e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG48124.1 - 4.1e-11 42.9 0.0 5.2e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG48124.1 - 5.5e-11 43.1 0.0 9.7e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG48124.1 - 3.1e-06 27.1 0.0 4.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KXG48124.1 - 0.014 15.3 0.0 0.084 12.7 0.0 2.1 2 1 0 2 2 2 0 Hypothetical methyltransferase AA_permease PF00324.21 KXG48125.1 - 1.9e-106 356.5 42.6 2.2e-106 356.3 42.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG48125.1 - 4e-36 124.8 46.9 4.5e-36 124.6 46.9 1.0 1 0 0 1 1 1 1 Amino acid permease Halogen_Hydrol PF10112.9 KXG48125.1 - 5.6 6.9 7.2 18 5.3 0.3 2.8 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Fungal_trans PF04082.18 KXG48126.1 - 1.7e-14 53.5 0.0 2.5e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KXG48127.1 - 2.3e-69 234.4 10.9 5.4e-52 177.2 1.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXG48127.1 - 2.6e-17 62.8 34.4 1.6e-11 43.7 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG48127.1 - 0.0026 16.2 0.3 0.0041 15.6 0.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3792 PF12670.7 KXG48127.1 - 0.66 10.2 19.0 0.027 14.6 6.7 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3792) AnmK PF03702.14 KXG48128.1 - 2.3e-84 283.6 0.0 2.7e-84 283.4 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase NAGidase PF07555.13 KXG48130.1 - 6e-101 337.6 1.6 8.5e-101 337.1 1.6 1.2 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase Glyco_hydro_20b PF02838.15 KXG48130.1 - 8e-21 75.1 0.2 1.8e-20 74.0 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_67N PF03648.14 KXG48130.1 - 0.0041 17.4 0.1 0.0082 16.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus DUF917 PF06032.12 KXG48130.1 - 0.012 14.4 0.6 0.021 13.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF917) Ig_mannosidase PF17753.1 KXG48131.1 - 4.8e-22 77.5 0.2 1.7e-21 75.7 0.1 2.0 2 0 0 2 2 2 1 Ig-fold domain Mannosidase_ig PF17786.1 KXG48131.1 - 8.7e-13 48.7 0.0 1.6e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Ig_GlcNase PF18368.1 KXG48131.1 - 0.051 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Exo-beta-D-glucosaminidase Ig-fold domain Y_phosphatase3 PF13350.6 KXG48132.1 - 1.5e-55 188.7 0.0 1.8e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KXG48132.1 - 1.6e-05 24.6 0.0 2.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KXG48132.1 - 0.00045 19.8 0.0 0.0011 18.6 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KXG48132.1 - 0.021 14.9 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Myotub-related PF06602.14 KXG48132.1 - 0.025 13.5 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain E1_dh PF00676.20 KXG48134.1 - 2.4e-89 299.3 0.0 3e-89 298.9 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KXG48134.1 - 0.00012 21.9 0.0 0.0016 18.3 0.0 2.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ish1 PF10281.9 KXG48134.1 - 0.024 15.0 0.2 0.024 15.0 0.2 1.7 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein XFP_N PF09364.10 KXG48134.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 XFP N-terminal domain Spherulin4 PF12138.8 KXG48135.1 - 3.6e-51 174.1 1.7 4.2e-51 173.9 1.7 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 zf-RING_4 PF14570.6 KXG48136.1 - 1.8e-19 69.3 13.5 3.6e-19 68.3 13.5 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KXG48136.1 - 3.2e-06 26.9 6.8 5.6e-06 26.1 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KXG48136.1 - 0.00016 21.4 0.0 0.00036 20.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 KXG48136.1 - 0.00081 19.7 10.6 0.0016 18.7 10.6 1.5 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 KXG48136.1 - 0.0051 16.8 4.5 0.0094 15.9 4.5 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 KXG48136.1 - 0.068 13.0 8.4 0.49 10.3 8.7 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KXG48136.1 - 0.11 12.4 12.2 0.22 11.4 12.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXG48136.1 - 0.79 9.7 11.7 1.5 8.9 11.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXG48136.1 - 1 9.4 10.1 2.3 8.3 10.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.7 KXG48136.1 - 5.7 7.1 10.5 1.3e+02 2.7 11.2 2.4 1 1 1 2 2 2 0 Double zinc ribbon Rtf2 PF04641.12 KXG48136.1 - 8.3 5.7 19.2 0.032 13.6 2.4 2.9 2 0 0 2 2 2 0 Rtf2 RING-finger Complex1_30kDa PF00329.19 KXG48137.1 - 2e-45 154.3 0.0 2.9e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BUD22 PF09073.10 KXG48138.1 - 1.6e-103 347.4 19.0 1.8e-103 347.2 19.0 1.0 1 0 0 1 1 1 1 BUD22 Cwf_Cwc_15 PF04889.12 KXG48138.1 - 10 5.8 17.6 0.73 9.5 9.7 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Spt46 PF17734.1 KXG48138.1 - 10 5.9 8.3 0.12 12.2 0.5 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 46 Fungal_trans PF04082.18 KXG48139.1 - 4e-28 98.2 0.0 6.8e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG48139.1 - 2.8e-05 24.1 10.8 4.9e-05 23.4 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Shikimate_DH PF01488.20 KXG48140.1 - 9.2e-05 22.5 0.0 0.0029 17.7 0.0 2.3 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_alpha PF03313.15 KXG48140.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain Pro_dh PF01619.18 KXG48141.1 - 6.9e-64 216.2 0.1 8.7e-64 215.9 0.1 1.1 1 0 0 1 1 1 1 Proline dehydrogenase AA_permease PF00324.21 KXG48142.1 - 7e-103 344.8 42.4 2.1e-101 339.9 42.4 2.1 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG48142.1 - 2.7e-22 79.2 45.0 4.5e-19 68.6 45.0 3.0 1 1 0 1 1 1 1 Amino acid permease Aldedh PF00171.22 KXG48143.1 - 1.5e-107 360.0 0.0 1.8e-107 359.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AP_endonuc_2 PF01261.24 KXG48144.1 - 1.3e-36 126.0 0.0 2.2e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel 6PGD PF00393.19 KXG48145.1 - 5.9e-84 281.9 0.0 7.3e-84 281.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KXG48145.1 - 5.4e-36 124.1 0.1 1.2e-35 123.0 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KXG48145.1 - 5e-05 23.3 0.1 8.1e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXG48145.1 - 0.0058 16.2 0.1 0.099 12.2 0.1 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KXG48145.1 - 0.0061 15.9 0.3 0.012 15.0 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXG48145.1 - 0.037 14.6 0.1 0.096 13.3 0.1 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KXG48145.1 - 0.06 13.0 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KXG48145.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PNP_UDP_1 PF01048.20 KXG48146.1 - 1.2e-41 142.5 0.2 1.5e-41 142.2 0.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily GHL6 PF14871.6 KXG48146.1 - 0.14 12.3 0.1 12 6.1 0.0 3.0 2 1 1 3 3 3 0 Hypothetical glycosyl hydrolase 6 Abhydrolase_6 PF12697.7 KXG48148.1 - 1.3e-16 61.9 0.0 1.4e-16 61.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KXG48148.1 - 0.00037 19.5 0.0 0.00059 18.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KXG48148.1 - 0.00075 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXG48148.1 - 0.0026 17.4 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KXG48148.1 - 0.018 14.8 0.1 0.036 13.8 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 KXG48148.1 - 0.02 15.0 0.0 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.13 KXG48148.1 - 0.064 13.0 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase PF07224.11 KXG48148.1 - 0.088 11.8 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase DUF747 PF05346.11 KXG48149.1 - 3.5e-118 394.7 3.0 4.5e-118 394.4 3.0 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family KCH PF16944.5 KXG48150.1 - 3.3e-101 338.3 4.2 3.9e-101 338.0 4.2 1.0 1 0 0 1 1 1 1 Fungal potassium channel adh_short PF00106.25 KXG48151.1 - 5.5e-09 35.8 0.0 1e-08 34.9 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG48151.1 - 0.001 18.6 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG48151.1 - 0.0072 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 KR domain p450 PF00067.22 KXG48152.1 - 8.6e-65 219.3 0.0 7.2e-64 216.2 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_4 PF08386.10 KXG48153.1 - 9.5e-23 80.3 0.0 5.6e-22 77.8 0.0 2.0 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 KXG48153.1 - 5.7e-19 68.8 0.0 1.1e-13 51.4 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold EDR1 PF14381.6 KXG48153.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 TPR_12 PF13424.6 KXG48154.1 - 6e-14 52.1 11.9 1.4e-09 38.1 0.3 6.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXG48154.1 - 2.6e-07 30.3 17.8 0.0044 16.8 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat NACHT PF05729.12 KXG48154.1 - 4.3e-07 30.0 0.2 1.8e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 NACHT domain TPR_7 PF13176.6 KXG48154.1 - 2.8e-05 23.8 3.7 3.5 7.9 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXG48154.1 - 0.0013 18.6 14.2 17 5.8 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_16 PF13191.6 KXG48154.1 - 0.0071 16.7 0.0 0.051 13.9 0.0 2.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXG48154.1 - 0.0082 16.4 0.0 0.033 14.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_19 PF14559.6 KXG48154.1 - 0.019 15.4 4.4 5.9 7.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXG48154.1 - 0.041 14.7 8.3 1.3e+02 3.8 0.1 6.9 4 2 2 6 6 6 0 Tetratricopeptide repeat Sigma54_activ_2 PF14532.6 KXG48154.1 - 0.048 13.8 0.0 0.74 9.9 0.0 2.5 1 1 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KXG48154.1 - 0.063 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TPR_1 PF00515.28 KXG48154.1 - 0.28 11.1 8.3 4.2 7.3 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Asparaginase_2 PF01112.18 KXG48155.1 - 2.5e-54 184.4 0.0 2.1e-49 168.2 0.0 3.3 3 1 0 3 3 3 2 Asparaginase Zn_clus PF00172.18 KXG48155.1 - 2.1e-06 27.7 5.8 4.2e-06 26.8 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_2 PF13409.6 KXG48156.1 - 2.6e-12 46.9 0.1 6.9e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXG48156.1 - 2.8e-12 46.9 0.0 4.5e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXG48156.1 - 3.5e-12 46.5 0.0 5.4e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXG48156.1 - 2.4e-06 27.7 0.0 5.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXG48156.1 - 7.1e-06 26.1 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXG48156.1 - 0.022 14.8 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TruD PF01142.18 KXG48156.1 - 0.17 10.6 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) FAA_hydrolase PF01557.18 KXG48157.1 - 3.6e-55 187.0 0.0 4.7e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KXG48157.1 - 7.9e-33 112.9 0.1 1.2e-32 112.2 0.1 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal HgmA PF04209.13 KXG48158.1 - 1.3e-210 699.6 0.1 1.4e-210 699.4 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase TPR_17 PF13431.6 KXG48159.1 - 0.0006 20.0 0.2 0.029 14.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXG48159.1 - 0.16 11.7 0.2 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 TPR repeat Glyoxalase PF00903.25 KXG48160.1 - 5.7e-20 71.8 0.4 6e-16 58.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXG48160.1 - 1.1e-12 48.1 0.1 4.3e-06 27.0 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KXG48160.1 - 5.1e-07 30.0 0.1 0.019 15.1 0.1 2.8 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KXG48160.1 - 6.8e-06 26.3 0.2 0.00018 21.7 0.1 2.5 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF4844 PF16133.5 KXG48160.1 - 0.08 13.5 0.1 0.31 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) zinc_ribbon_15 PF17032.5 KXG48161.1 - 0.00026 21.7 1.6 0.0031 18.2 0.1 2.4 2 0 0 2 2 2 1 zinc-ribbon family zf_CCCH_4 PF18345.1 KXG48161.1 - 0.0015 18.5 2.0 0.0048 16.9 2.0 1.9 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KXG48161.1 - 0.0077 16.1 2.4 0.0077 16.1 2.4 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DZR PF12773.7 KXG48161.1 - 0.77 9.8 5.3 3.1 7.9 0.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon E7 PF00527.18 KXG48161.1 - 3.2 8.0 5.2 6.1 7.1 0.0 2.8 2 0 0 2 2 2 0 E7 protein, Early protein DUF3295 PF11702.8 KXG48162.1 - 3.4e-192 640.2 23.9 4e-192 640.0 23.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KXG48162.1 - 2.3e-12 46.5 1.9 6.2e-12 45.1 1.9 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Cpn60_TCP1 PF00118.24 KXG48163.1 - 1.5e-155 518.6 4.3 1.7e-155 518.4 4.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chromo_shadow PF01393.19 KXG48164.1 - 1.3e-17 63.6 1.3 5.2e-15 55.3 0.1 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KXG48164.1 - 1.3e-09 37.8 1.0 2.4e-09 37.0 1.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF908 PF06012.12 KXG48164.1 - 0.071 12.5 0.3 0.064 12.7 0.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Rap1_C PF11626.8 KXG48165.1 - 1.2e-22 79.8 0.0 1.7e-21 76.1 0.0 2.2 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 KXG48165.1 - 2.7e-17 62.7 0.1 7.3e-17 61.3 0.0 1.8 2 0 0 2 2 2 1 Rap1 Myb domain BRCT_2 PF16589.5 KXG48165.1 - 1.9e-11 44.2 0.0 3.2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DHHC PF01529.20 KXG48166.1 - 5.8e-31 107.4 7.1 5.8e-31 107.4 7.1 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Adeno_E1A PF02703.14 KXG48166.1 - 0.35 10.4 1.6 0.51 9.9 1.6 1.2 1 0 0 1 1 1 0 Early E1A protein Atx10homo_assoc PF09759.9 KXG48167.1 - 1.7e-31 108.2 0.5 4.7e-31 106.7 0.1 2.0 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain zf-RING_2 PF13639.6 KXG48168.1 - 2.5e-08 34.1 2.5 3.7e-08 33.6 2.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXG48168.1 - 6.2e-06 26.4 3.4 4.5e-05 23.7 3.4 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXG48168.1 - 0.00051 20.0 6.4 0.00085 19.3 6.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXG48168.1 - 0.0022 18.0 0.6 0.0035 17.4 0.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_9 PF14369.6 KXG48168.1 - 0.0045 17.2 0.4 0.01 16.1 0.4 1.6 1 0 0 1 1 1 1 zinc-ribbon zf-C3HC4_2 PF13923.6 KXG48168.1 - 0.0061 16.4 3.7 0.017 15.0 3.5 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXG48168.1 - 0.025 14.4 0.9 0.044 13.7 0.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXG48168.1 - 0.035 13.9 1.3 0.06 13.1 1.3 1.4 1 0 0 1 1 1 0 RING-like zinc finger LPD38 PF18857.1 KXG48168.1 - 0.12 12.5 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 38 Putative_PNPOx PF01243.20 KXG48169.1 - 2.6e-12 46.7 0.0 8.5e-06 25.9 0.0 2.6 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 KXG48169.1 - 0.00012 22.4 0.0 0.00061 20.1 0.0 2.2 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain E1-E2_ATPase PF00122.20 KXG48170.1 - 1.7 8.1 3.5 2.7 7.5 3.5 1.4 1 0 0 1 1 1 0 E1-E2 ATPase DUF2070 PF09843.9 KXG48170.1 - 8.1 4.6 13.6 10 4.3 13.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) NTP_transferase PF00483.23 KXG48171.1 - 7.1e-31 107.7 0.0 1.1e-30 107.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KXG48171.1 - 8.8e-09 35.9 0.0 1.4e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KXG48171.1 - 5.6e-08 32.2 4.2 1.1e-05 24.9 0.1 3.3 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) IspD PF01128.19 KXG48171.1 - 0.0052 16.6 0.0 0.0093 15.7 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Abhydrolase_6 PF12697.7 KXG48174.1 - 7.2e-15 56.2 0.6 9e-15 55.9 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 KXG48174.1 - 0.0038 16.8 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 KXG48174.1 - 0.059 13.1 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein RcnB PF11776.8 KXG48174.1 - 0.085 12.9 0.2 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 Nickel/cobalt transporter regulator DUF676 PF05057.14 KXG48174.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Dynamin_N PF00350.23 KXG48175.1 - 6.4e-25 88.1 0.0 7.5e-24 84.7 0.0 2.7 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KXG48175.1 - 8.3e-23 81.0 0.8 5.2e-19 68.5 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 KXG48175.1 - 0.00049 20.2 0.0 0.0021 18.2 0.0 2.2 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXG48175.1 - 0.00058 19.9 0.0 0.01 15.9 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arc_C PF18162.1 KXG48175.1 - 0.0024 17.7 0.2 0.008 16.0 0.1 1.9 2 0 0 2 2 2 1 Arc C-lobe Roc PF08477.13 KXG48175.1 - 0.017 15.4 0.5 0.21 11.8 0.0 3.0 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 KXG48175.1 - 0.036 13.1 0.0 4.6 6.2 0.0 2.5 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_15 PF13175.6 KXG48175.1 - 0.26 10.9 1.2 1.8 8.2 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain tRNA-synt_2 PF00152.20 KXG48176.1 - 4.8e-76 255.8 0.8 6.4e-76 255.4 0.8 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXG48176.1 - 4.2e-13 49.1 0.1 9.3e-13 48.0 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXG48176.1 - 0.00039 20.0 0.2 0.58 9.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF3512 PF12024.8 KXG48176.1 - 0.13 11.7 0.3 0.27 10.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) zf-C3HC4_3 PF13920.6 KXG48176.1 - 0.27 11.1 5.9 0.66 9.9 5.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-4CXXC_R1 PF10497.9 KXG48176.1 - 0.4 10.9 6.3 1.1 9.5 6.3 1.7 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-B_box PF00643.24 KXG48176.1 - 0.48 10.6 4.3 1 9.6 4.3 1.5 1 0 0 1 1 1 0 B-box zinc finger zf-C3HC4_2 PF13923.6 KXG48176.1 - 0.9 9.4 5.2 0.92 9.4 3.4 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXG48176.1 - 7.7 6.6 8.3 24 5.0 5.9 2.4 2 0 0 2 2 2 0 zinc-RING finger domain COX15-CtaA PF02628.15 KXG48177.1 - 1.1e-115 386.2 5.0 1.3e-115 385.9 5.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein zf-C3HC PF07967.13 KXG48178.1 - 6.1e-40 136.3 0.2 3.9e-37 127.3 0.1 2.4 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 KXG48178.1 - 1.5e-34 118.1 1.0 3.5e-32 110.4 0.0 2.9 3 0 0 3 3 3 2 Rsm1-like Pox_MCEL PF03291.16 KXG48179.1 - 8.5e-68 228.9 0.0 8.3e-44 150.0 0.0 3.3 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 KXG48179.1 - 6.5e-09 36.4 0.0 0.0048 17.6 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXG48179.1 - 4.8e-08 33.6 0.0 3.3e-07 31.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG48179.1 - 2.9e-06 27.8 0.0 0.017 15.8 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KXG48179.1 - 6e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG48179.1 - 0.00018 21.3 0.0 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KXG48179.1 - 0.05 12.8 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family zf-Nse PF11789.8 KXG48180.1 - 8.2e-23 80.0 1.1 1.8e-22 78.9 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KXG48180.1 - 0.00049 20.1 0.2 0.0027 17.7 0.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXG48180.1 - 0.0041 16.9 1.2 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 KXG48180.1 - 0.02 14.6 3.4 0.13 12.0 3.4 2.0 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_2 PF13639.6 KXG48180.1 - 0.23 11.8 1.4 0.49 10.8 1.4 1.6 1 1 0 1 1 1 0 Ring finger domain MFS_1 PF07690.16 KXG48181.1 - 2.8e-11 42.9 28.1 2.8e-11 42.9 28.1 1.7 3 0 0 3 3 3 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXG48181.1 - 3.8e-08 33.2 4.6 3.8e-08 33.2 4.6 2.8 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 Mito_carr PF00153.27 KXG48182.1 - 3.1e-55 184.1 3.4 6.6e-18 64.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.22 KXG48183.1 - 2.3e-57 194.8 0.0 3.2e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PEPCK_ATP PF01293.20 KXG48184.1 - 1.3e-214 713.2 0.0 1.5e-214 712.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 KXG48184.1 - 0.15 12.2 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain Abhydrolase_3 PF07859.13 KXG48186.1 - 1.3e-35 123.2 0.0 1.9e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXG48186.1 - 1.8e-11 43.6 0.0 4.4e-11 42.3 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KXG48186.1 - 0.019 13.8 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase PEX11 PF05648.14 KXG48188.1 - 1.7e-75 253.4 0.1 1.9e-75 253.2 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) TBPIP PF07106.13 KXG48188.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain Arch_fla_DE PF04659.13 KXG48188.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Archaeal flagella protein Sugar_tr PF00083.24 KXG48189.1 - 6.8e-31 107.6 29.0 7.7e-22 77.8 9.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXG48189.1 - 5.1e-16 58.6 64.1 1.5e-14 53.7 41.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0182 PF03699.13 KXG48189.1 - 0.11 10.6 0.2 0.21 9.7 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) SurA_N_3 PF13624.6 KXG48189.1 - 2.2 8.0 5.6 5 6.9 0.2 2.9 3 0 0 3 3 3 0 SurA N-terminal domain PDR_CDR PF06422.12 KXG48189.1 - 2.4 8.1 6.3 8.8 6.3 0.1 3.5 3 0 0 3 3 3 0 CDR ABC transporter RPN7 PF10602.9 KXG48190.1 - 3.2e-53 180.0 0.2 5e-53 179.4 0.2 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KXG48190.1 - 5.2e-15 55.8 0.0 1.2e-14 54.7 0.0 1.7 1 0 0 1 1 1 1 PCI domain Aminotran_1_2 PF00155.21 KXG48191.1 - 7.8e-39 133.9 0.0 1.1e-38 133.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Exo_endo_phos PF03372.23 KXG48192.1 - 3.5e-05 23.4 0.0 6.1e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Copper-fist PF00649.18 KXG48193.1 - 1.9e-21 75.2 2.9 1.9e-21 75.2 2.9 2.1 2 0 0 2 2 2 1 Copper fist DNA binding domain Zn_clus PF00172.18 KXG48194.1 - 2.8e-10 40.2 8.2 4.6e-10 39.5 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IL34 PF15036.6 KXG48194.1 - 0.065 13.3 0.1 3 7.8 0.0 2.3 2 0 0 2 2 2 0 Interleukin 34 DELLA PF12041.8 KXG48194.1 - 0.069 13.0 0.0 1.8 8.5 0.0 2.7 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal zf_ZIC PF18366.1 KXG48196.1 - 0.001 19.1 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 Zic proteins zinc finger domain SspK PF08176.12 KXG48196.1 - 0.017 15.3 0.0 0.071 13.4 0.0 2.1 2 0 0 2 2 2 0 Small acid-soluble spore protein K family RFX_DNA_binding PF02257.15 KXG48196.1 - 0.024 15.3 0.0 0.049 14.3 0.0 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain RPE65 PF03055.15 KXG48197.1 - 1.9e-115 386.7 0.0 2.2e-115 386.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Fungal_trans PF04082.18 KXG48198.1 - 4.2e-15 55.5 0.1 6.6e-15 54.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG48198.1 - 6.9e-08 32.5 12.4 8.2e-08 32.3 7.8 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 KXG48198.1 - 0.21 10.0 0.1 0.31 9.4 0.1 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B ArfGap PF01412.18 KXG48200.1 - 9.3e-40 135.4 0.2 1.3e-39 134.8 0.2 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelR PF01641.18 KXG48201.1 - 2.4e-50 169.7 0.1 2.7e-50 169.5 0.1 1.0 1 0 0 1 1 1 1 SelR domain MCM_OB PF17207.3 KXG48201.1 - 0.033 14.0 0.1 0.063 13.1 0.0 1.4 2 0 0 2 2 2 0 MCM OB domain TackOD1 PF18551.1 KXG48201.1 - 0.039 13.6 0.2 0.095 12.4 0.1 1.6 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 zinc_ribbon_10 PF10058.9 KXG48201.1 - 0.044 13.5 0.4 0.44 10.3 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DZR PF12773.7 KXG48201.1 - 0.064 13.3 1.5 5.2 7.2 0.1 2.4 2 1 0 2 2 2 0 Double zinc ribbon DNA_RNApol_7kD PF03604.13 KXG48201.1 - 1.2 8.9 4.1 13 5.5 0.4 2.7 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Smr PF01713.21 KXG48202.1 - 0.0062 16.9 0.1 0.016 15.6 0.1 1.7 1 0 0 1 1 1 1 Smr domain CUE PF02845.16 KXG48202.1 - 0.011 15.5 0.1 0.024 14.3 0.1 1.7 1 0 0 1 1 1 0 CUE domain YCII PF03795.14 KXG48203.1 - 1.9e-06 28.2 0.0 2.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Zds_C PF08632.10 KXG48204.1 - 1.8e-27 94.8 1.6 3.2e-27 94.0 1.6 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Ysc84 PF04366.12 KXG48205.1 - 1.9e-39 134.4 0.7 3.4e-39 133.5 0.7 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KXG48205.1 - 1.1e-12 47.3 0.2 3.6e-12 45.7 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KXG48205.1 - 1.7e-11 43.6 0.3 6.5e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KXG48205.1 - 8.7e-10 38.3 0.0 1.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain EF_assoc_2 PF08356.12 KXG48206.1 - 1.1e-34 118.2 0.0 2e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KXG48206.1 - 2.1e-30 104.1 0.1 3.8e-30 103.3 0.1 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KXG48206.1 - 4.7e-24 84.8 0.0 5.3e-14 52.1 0.0 2.5 3 0 0 3 3 2 2 Ras family Roc PF08477.13 KXG48206.1 - 1.7e-11 44.4 0.0 1.7e-06 28.2 0.0 3.5 4 0 0 4 4 3 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXG48206.1 - 2.4e-09 37.3 0.0 0.00032 20.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase ANAPC4_WD40 PF12894.7 KXG48206.1 - 7.4e-09 35.8 0.0 0.0058 16.9 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXG48206.1 - 5.8e-08 33.3 11.5 0.0013 19.5 0.3 5.7 5 0 0 5 5 5 1 WD domain, G-beta repeat EF-hand_1 PF00036.32 KXG48206.1 - 9.6e-07 27.9 1.0 0.019 14.5 0.2 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KXG48206.1 - 9.6e-06 25.1 0.9 0.02 14.8 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain IKI3 PF04762.12 KXG48206.1 - 2.5e-05 22.5 0.0 0.0037 15.3 0.0 2.1 1 1 1 2 2 2 2 IKI3 family EF-hand_7 PF13499.6 KXG48206.1 - 6.8e-05 23.2 0.1 0.027 14.9 0.1 3.1 3 0 0 3 3 2 1 EF-hand domain pair AAA_29 PF13555.6 KXG48206.1 - 8.7e-05 22.2 0.3 0.034 13.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KXG48206.1 - 0.00019 21.8 0.1 0.32 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KXG48206.1 - 0.0014 19.2 0.0 2.9 8.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXG48206.1 - 0.0016 18.8 0.3 3.4 8.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXG48206.1 - 0.0018 18.6 0.0 0.46 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KXG48206.1 - 0.0019 18.3 0.9 1.1 9.3 0.0 2.9 3 0 0 3 3 2 1 Dynamin family GTP_EFTU PF00009.27 KXG48206.1 - 0.0029 17.2 0.1 6.7 6.2 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Viral_helicase1 PF01443.18 KXG48206.1 - 0.007 16.1 0.3 0.078 12.7 0.0 2.5 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 KXG48206.1 - 0.011 15.6 0.2 4.1 7.3 0.1 3.3 3 0 0 3 3 3 0 RsgA GTPase EF-hand_5 PF13202.6 KXG48206.1 - 0.014 14.9 2.0 0.48 10.0 0.2 2.7 2 0 0 2 2 2 0 EF hand RNA_helicase PF00910.22 KXG48206.1 - 0.014 15.8 0.0 2.2 8.7 0.0 2.9 2 0 0 2 2 2 0 RNA helicase EF-hand_8 PF13833.6 KXG48206.1 - 0.015 15.2 0.4 2.5 8.0 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair ABC_tran PF00005.27 KXG48206.1 - 0.031 14.8 0.1 12 6.4 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Cytochrom_D1 PF02239.16 KXG48206.1 - 0.033 12.7 0.0 0.057 11.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain NACHT PF05729.12 KXG48206.1 - 0.033 14.1 0.2 8.8 6.2 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KXG48206.1 - 0.035 13.7 0.0 5.9 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KXG48206.1 - 0.044 13.1 0.2 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KXG48206.1 - 0.072 12.8 0.1 0.56 9.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KXG48206.1 - 0.089 12.7 0.0 5.3 6.9 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 eIF2A PF08662.11 KXG48206.1 - 0.097 12.5 0.1 0.4 10.5 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A AAA_33 PF13671.6 KXG48206.1 - 0.099 12.8 0.1 14 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain EF-hand_10 PF14788.6 KXG48206.1 - 0.12 12.3 1.0 0.48 10.3 0.2 2.2 2 0 0 2 2 2 0 EF hand AAA_7 PF12775.7 KXG48206.1 - 0.13 11.7 0.1 3 7.3 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region YpsA PF06908.11 KXG48206.1 - 0.21 11.6 0.0 9.6 6.2 0.0 2.3 2 0 0 2 2 2 0 YspA SLOG family DUF815 PF05673.13 KXG48206.1 - 0.25 10.5 0.2 4.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) GPI-anchored PF10342.9 KXG48207.1 - 5.7e-19 68.7 1.9 5.7e-19 68.7 1.9 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AAA_22 PF13401.6 KXG48208.1 - 0.0012 19.1 0.2 0.47 10.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KXG48208.1 - 0.0021 18.5 0.4 0.013 15.9 0.1 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 KXG48208.1 - 0.019 15.0 0.0 1.4 9.0 0.2 2.5 3 0 0 3 3 3 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KXG48208.1 - 0.048 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 KXG48208.1 - 0.078 12.3 0.0 0.25 10.6 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_10 PF12846.7 KXG48208.1 - 0.097 11.6 0.3 7.1 5.4 0.0 2.4 3 0 0 3 3 3 0 AAA-like domain Ank_2 PF12796.7 KXG48209.1 - 5.5e-15 55.7 0.0 1.3e-10 41.7 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG48209.1 - 9.2e-15 54.8 1.4 4e-07 30.5 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG48209.1 - 3.4e-11 42.3 1.6 0.066 13.8 0.0 6.2 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 KXG48209.1 - 1.4e-06 28.5 1.4 0.076 13.5 0.0 5.0 4 1 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KXG48209.1 - 1.3e-05 25.4 0.5 0.2 12.0 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Fungal_trans_2 PF11951.8 KXG48210.1 - 0.00015 20.7 0.0 0.00026 19.9 0.0 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.13 KXG48211.1 - 9e-39 133.2 6.6 1.3e-38 132.7 6.6 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4131 PF13567.6 KXG48211.1 - 1.5 8.5 5.2 1.1 8.9 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4029 PF13221.6 KXG48211.1 - 3.4 8.4 6.0 2.8 8.7 1.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4029) DAO PF01266.24 KXG48212.1 - 4.7e-40 138.3 0.0 6.4e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Zn_clus PF00172.18 KXG48212.1 - 2.5e-09 37.1 8.8 5.5e-09 36.0 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_8 PF13450.6 KXG48212.1 - 2.4e-05 24.5 0.0 6.8e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG48212.1 - 0.00061 19.1 0.0 0.026 13.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG48212.1 - 0.0025 17.0 0.0 0.11 11.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Glu_dehyd_C PF16912.5 KXG48212.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus GIDA PF01134.22 KXG48212.1 - 0.021 13.9 0.0 0.26 10.3 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KXG48212.1 - 0.024 13.9 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KXG48212.1 - 0.027 14.5 0.4 2.7 8.0 0.0 2.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXG48212.1 - 0.042 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXG48212.1 - 0.044 13.8 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 KXG48212.1 - 0.075 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXG48212.1 - 0.16 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Arrestin_C PF02752.22 KXG48214.1 - 5.6e-20 72.2 0.0 1.7e-19 70.6 0.1 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KXG48214.1 - 1.4e-10 41.4 0.0 2.2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KXG48214.1 - 0.0082 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like YfcL PF08891.11 KXG48215.1 - 0.1 13.0 0.3 11 6.4 0.0 2.6 2 0 0 2 2 2 0 YfcL protein PH PF00169.29 KXG48215.1 - 0.15 12.6 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 PH domain TolA_bind_tri PF16331.5 KXG48215.1 - 0.66 10.1 3.5 1.9 8.6 3.5 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation Nup54 PF13874.6 KXG48215.1 - 8.9 6.4 9.1 5.3 7.1 1.3 2.9 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Glyoxalase PF00903.25 KXG48217.1 - 8.3e-40 135.9 0.0 4.6e-19 68.9 0.0 2.9 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.18 KXG48217.1 - 3.3e-19 69.0 0.0 6.1e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase_4 PF13669.6 KXG48217.1 - 6e-12 45.8 0.0 0.00011 22.4 0.0 3.8 1 1 3 4 4 4 4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KXG48217.1 - 9.5e-05 22.6 0.0 0.17 12.0 0.0 3.5 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KXG48217.1 - 0.00035 21.3 0.0 2.5 9.0 0.0 3.3 2 1 0 2 2 2 2 Glyoxalase-like domain Pkinase PF00069.25 KXG48218.1 - 7.2e-70 235.4 0.0 9.2e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48218.1 - 5.8e-30 104.4 0.0 7.4e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXG48218.1 - 0.00027 20.0 0.1 0.022 13.7 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 KXG48218.1 - 0.00081 18.8 0.0 0.0015 17.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXG48218.1 - 0.013 15.4 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KXG48218.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 2OG-FeII_Oxy_2 PF13532.6 KXG48219.1 - 1.8e-26 93.6 0.0 3.8e-26 92.5 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidase PF01425.21 KXG48220.1 - 2.3e-101 340.0 0.0 2.9e-101 339.7 0.0 1.1 1 0 0 1 1 1 1 Amidase ABC2_membrane PF01061.24 KXG48221.1 - 1.3e-84 282.9 55.2 7.7e-47 159.4 22.9 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KXG48221.1 - 7e-37 127.0 0.0 2.6e-17 63.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXG48221.1 - 7e-29 99.6 11.7 3.3e-26 91.0 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KXG48221.1 - 1.5e-10 41.5 1.4 3.2e-10 40.5 0.1 2.4 2 0 0 2 2 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KXG48221.1 - 7.1e-08 31.9 38.7 2.5e-06 26.9 17.4 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KXG48221.1 - 8.8e-07 29.5 0.2 6.4e-05 23.4 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KXG48221.1 - 1.6e-05 24.9 2.0 0.12 12.2 0.1 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KXG48221.1 - 2e-05 25.1 0.1 0.0098 16.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KXG48221.1 - 4.2e-05 23.2 0.1 0.0092 15.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXG48221.1 - 4.6e-05 23.4 0.1 0.00016 21.6 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KXG48221.1 - 0.00022 21.5 0.2 0.1 12.9 0.2 3.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXG48221.1 - 0.00037 20.1 0.1 0.0048 16.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KXG48221.1 - 0.0017 18.6 0.4 0.19 11.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KXG48221.1 - 0.0049 16.8 0.1 0.07 13.1 0.0 2.6 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 KXG48221.1 - 0.0055 16.5 0.2 0.067 12.9 0.2 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KXG48221.1 - 0.0058 16.0 0.1 2.6 7.3 0.1 3.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_28 PF13521.6 KXG48221.1 - 0.0065 16.7 0.1 0.0065 16.7 0.1 2.4 3 0 0 3 3 1 1 AAA domain AAA_17 PF13207.6 KXG48221.1 - 0.0073 16.7 0.1 0.23 11.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KXG48221.1 - 0.018 14.6 0.1 0.21 11.2 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KXG48221.1 - 0.021 14.9 0.4 0.8 9.8 0.3 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_ATPase PF09818.9 KXG48221.1 - 0.025 13.4 0.1 1.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class dNK PF01712.19 KXG48221.1 - 0.037 13.9 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_23 PF13476.6 KXG48221.1 - 0.067 13.7 2.2 0.07 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KXG48221.1 - 0.074 12.5 0.1 8.7 5.7 0.0 2.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 KXG48221.1 - 0.14 11.2 0.3 0.34 9.9 0.1 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA PF00004.29 KXG48221.1 - 0.22 11.9 0.1 1.5 9.3 0.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-C2HC_2 PF13913.6 KXG48221.1 - 0.41 10.6 1.5 1.1 9.3 0.2 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 KXG48221.1 - 4 8.5 4.5 2.5 9.2 0.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger ThiJ_like PF17124.5 KXG48223.1 - 6.9e-12 45.5 0.0 8.7e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 KXG48223.1 - 3.6e-11 43.1 0.0 1.3e-10 41.4 0.0 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family Glyco_transf_4 PF13439.6 KXG48223.1 - 0.1 12.6 0.0 0.37 10.8 0.0 1.8 1 1 0 1 1 1 0 Glycosyltransferase Family 4 AMP-binding PF00501.28 KXG48224.1 - 4e-57 193.7 0.0 6e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KXG48224.1 - 6.2e-12 45.7 0.0 1.5e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 KXG48224.1 - 8.6e-11 41.1 10.5 1.1e-05 24.9 0.1 6.2 7 0 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXG48224.1 - 2e-05 24.2 10.2 0.7 9.7 0.2 6.3 6 0 0 6 6 6 3 Hexapeptide repeat of succinyl-transferase GH3 PF03321.13 KXG48224.1 - 0.18 10.6 0.0 0.91 8.3 0.0 1.9 2 0 0 2 2 2 0 GH3 auxin-responsive promoter DUF1993 PF09351.10 KXG48225.1 - 4.8e-54 182.8 0.2 5.4e-54 182.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) LOR PF04525.12 KXG48226.1 - 2.1e-07 30.7 0.1 3.6e-06 26.7 0.1 2.1 1 1 0 1 1 1 1 LURP-one-related Methyltransf_32 PF13679.6 KXG48227.1 - 8.8e-21 74.5 0.0 2.3e-20 73.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Dickkopf_N PF04706.12 KXG48228.1 - 0.35 11.4 4.8 0.66 10.5 4.8 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region CarbpepA_inh PF02977.15 KXG48228.1 - 0.69 9.8 10.1 1.6 8.6 10.0 1.7 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor Kdo PF06293.14 KXG48229.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_4 PF06347.13 KXG48229.1 - 0.18 11.6 0.6 0.32 10.8 0.6 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain NmrA PF05368.13 KXG48230.1 - 1.9e-24 86.5 0.3 2.5e-24 86.1 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG48230.1 - 2.5e-15 56.8 0.0 7e-15 55.4 0.0 1.7 1 1 1 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXG48230.1 - 9.1e-08 32.4 0.0 1.7e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KXG48230.1 - 2.1e-07 31.4 0.1 5.4e-07 30.1 0.0 1.7 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXG48230.1 - 3.5e-05 23.9 0.0 6.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KXG48230.1 - 0.00088 19.4 0.0 0.0018 18.4 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TRH PF05438.12 KXG48231.1 - 1.5 8.5 9.7 12 5.6 4.9 2.9 1 1 1 2 2 2 0 Thyrotropin-releasing hormone (TRH) DUF3328 PF11807.8 KXG48232.1 - 4.7e-60 203.1 1.4 6.1e-60 202.7 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) ABC_tran PF00005.27 KXG48233.1 - 3.5e-34 118.3 0.0 5.6e-16 59.3 0.0 3.2 2 2 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXG48233.1 - 3e-27 96.0 18.2 7.4e-27 94.7 9.6 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KXG48233.1 - 3.6e-10 39.7 6.6 0.0011 18.4 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXG48233.1 - 9.5e-08 31.7 1.3 0.0015 18.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXG48233.1 - 2.1e-07 31.0 0.3 0.0082 16.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KXG48233.1 - 6.1e-07 30.1 2.9 0.00035 21.2 0.3 2.3 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KXG48233.1 - 3.7e-05 23.7 0.3 0.68 9.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 KXG48233.1 - 3.7e-05 23.0 0.2 0.049 12.8 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain AAA_22 PF13401.6 KXG48233.1 - 3.9e-05 24.0 0.1 0.096 13.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KXG48233.1 - 8e-05 22.4 0.2 0.2 11.4 0.0 3.8 4 0 0 4 4 4 1 IstB-like ATP binding protein MMR_HSR1 PF01926.23 KXG48233.1 - 9.3e-05 22.5 0.5 0.044 13.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 KXG48233.1 - 0.00016 21.3 0.0 0.46 10.0 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 KXG48233.1 - 0.00023 20.9 0.1 0.043 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KXG48233.1 - 0.0011 18.0 0.1 0.086 11.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 KXG48233.1 - 0.0011 19.3 0.0 1.2 9.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 KXG48233.1 - 0.0037 17.5 0.4 1.3 9.2 0.1 3.2 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KXG48233.1 - 0.0045 16.8 1.9 2.1 8.0 0.7 2.2 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 KXG48233.1 - 0.0054 16.9 0.1 1.7 8.9 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 KXG48233.1 - 0.0058 16.7 2.0 0.23 11.5 0.1 2.4 2 0 0 2 2 2 1 Dynamin family ABC_ATPase PF09818.9 KXG48233.1 - 0.01 14.6 0.3 0.056 12.2 0.1 2.1 2 1 1 3 3 3 0 Predicted ATPase of the ABC class AAA_33 PF13671.6 KXG48233.1 - 0.011 16.0 0.1 3.6 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 KXG48233.1 - 0.012 15.5 0.2 0.32 10.9 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 KXG48233.1 - 0.014 15.8 0.0 0.25 11.8 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KXG48233.1 - 0.023 14.3 1.1 1.8 8.1 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KXG48233.1 - 0.027 14.4 0.2 9.3 6.1 0.1 2.7 2 0 0 2 2 2 0 NACHT domain Pox_A32 PF04665.12 KXG48233.1 - 0.029 13.9 0.2 0.46 9.9 0.0 2.7 3 0 0 3 3 3 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 KXG48233.1 - 0.032 13.6 0.2 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.6 KXG48233.1 - 0.033 14.4 1.8 3.8 7.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXG48233.1 - 0.094 13.3 0.1 3.8 8.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KXG48233.1 - 0.11 12.0 3.4 0.33 10.4 0.1 2.6 3 0 0 3 3 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KXG48233.1 - 0.12 12.8 0.2 26 5.2 0.0 3.4 3 0 0 3 3 3 0 RNA helicase TrwB_AAD_bind PF10412.9 KXG48233.1 - 0.13 11.1 0.0 0.27 10.1 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 KXG48233.1 - 0.17 11.1 0.2 0.51 9.6 0.0 1.9 2 0 0 2 2 1 0 Zeta toxin PRK PF00485.18 KXG48233.1 - 0.21 11.3 3.4 0.16 11.7 0.1 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF3611 PF12263.8 KXG48233.1 - 0.21 11.5 2.8 0.15 11.9 0.2 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF3611) DUF87 PF01935.17 KXG48233.1 - 0.51 10.4 1.8 1.7 8.7 0.2 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain ERG4_ERG24 PF01222.17 KXG48234.1 - 4e-146 487.1 7.2 4.8e-146 486.9 7.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KXG48234.1 - 1.5e-05 24.7 0.2 4e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Saf_2TM PF18303.1 KXG48234.1 - 0.076 12.6 0.1 0.6 9.7 0.0 2.4 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Ferlin_C PF16165.5 KXG48234.1 - 0.18 11.8 1.3 0.82 9.6 1.3 2.1 1 0 0 1 1 1 0 Ferlin C-terminus WGG PF10273.9 KXG48235.1 - 3.7e-30 104.4 0.8 7e-30 103.5 0.8 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Ribosomal_60s PF00428.19 KXG48235.1 - 0.063 13.9 7.8 0.22 12.1 7.8 1.9 1 1 0 1 1 1 0 60s Acidic ribosomal protein zf-ZPR1 PF03367.13 KXG48235.1 - 0.23 11.3 1.5 0.38 10.6 1.4 1.3 1 1 0 1 1 1 0 ZPR1 zinc-finger domain GTP_EFTU PF00009.27 KXG48236.1 - 1.9e-37 128.7 0.0 2.9e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXG48236.1 - 2.8e-28 98.5 0.0 5.4e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXG48236.1 - 0.00035 20.9 0.0 0.00092 19.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXG48236.1 - 0.0097 16.0 0.0 0.034 14.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF5035 PF16438.5 KXG48236.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5035) Ran-binding PF05508.11 KXG48237.1 - 2.8e-122 407.6 0.2 3.5e-122 407.3 0.2 1.1 1 0 0 1 1 1 1 RanGTP-binding protein RTP1_C2 PF10304.9 KXG48237.1 - 0.12 12.1 1.1 0.27 11.0 0.2 2.0 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 APP_amyloid PF10515.9 KXG48237.1 - 0.27 11.8 0.9 0.77 10.3 0.9 1.8 1 0 0 1 1 1 0 Beta-amyloid precursor protein C-terminus BSD PF03909.17 KXG48238.1 - 8.9e-20 70.5 1.3 1.7e-19 69.5 1.3 1.5 1 0 0 1 1 1 1 BSD domain KfrA_N PF11740.8 KXG48238.1 - 0.26 12.0 0.1 0.26 12.0 0.1 2.8 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term Rad4 PF03835.15 KXG48240.1 - 2.2e-35 121.5 0.1 6.2e-35 120.0 0.1 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KXG48240.1 - 2.8e-29 101.3 0.0 6e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KXG48240.1 - 2.7e-20 71.9 0.1 7.2e-20 70.6 0.1 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KXG48240.1 - 4.1e-18 66.1 0.1 4.1e-18 66.1 0.1 2.7 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 Cep57_MT_bd PF06657.13 KXG48240.1 - 0.015 15.7 0.2 0.047 14.1 0.2 1.8 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Transglut_core PF01841.19 KXG48240.1 - 0.016 15.7 0.0 0.047 14.1 0.0 1.9 1 0 0 1 1 1 0 Transglutaminase-like superfamily AbfS_sensor PF18225.1 KXG48240.1 - 0.024 14.6 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 0 Sensor histidine kinase (AbfS) sensor domain Methyltransf_23 PF13489.6 KXG48241.1 - 6.5e-22 78.1 0.0 9.6e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG48241.1 - 2.9e-10 40.7 0.0 6.9e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG48241.1 - 7.4e-08 32.3 0.0 8.5e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG48241.1 - 1.8e-07 31.8 0.0 1.1e-06 29.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG48241.1 - 1.3e-06 29.0 0.0 2.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG48241.1 - 0.001 18.4 0.0 0.005 16.2 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXG48241.1 - 0.0064 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.9 KXG48241.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KXG48241.1 - 0.029 13.8 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Proteasome PF00227.26 KXG48243.1 - 7e-45 152.9 0.1 9.1e-45 152.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KXG48243.1 - 2.9e-13 48.9 0.4 2.9e-13 48.9 0.4 1.9 2 0 0 2 2 2 1 Proteasome beta subunits C terminal ANAPC4_WD40 PF12894.7 KXG48244.1 - 0.041 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1664 PF07889.12 KXG48244.1 - 0.26 11.3 0.8 3 7.9 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KH_1 PF00013.29 KXG48246.1 - 2e-44 149.2 3.0 2.5e-17 62.4 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXG48246.1 - 2.1e-12 46.7 2.2 0.005 16.6 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KXG48246.1 - 3.8e-06 26.7 0.1 0.76 9.7 0.0 3.3 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 KXG48246.1 - 8.5e-05 22.5 0.0 0.016 15.2 0.0 2.5 2 0 0 2 2 2 1 KH-like RNA-binding domain KH_5 PF13184.6 KXG48246.1 - 0.00013 22.0 7.0 0.35 11.0 0.2 3.3 3 0 0 3 3 3 2 NusA-like KH domain SR-25 PF10500.9 KXG48246.1 - 1.2 8.7 6.6 2 8.0 6.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CENP-K PF11802.8 KXG48247.1 - 0.69 9.4 19.4 2.9 7.4 0.1 2.8 2 2 0 2 2 2 0 Centromere-associated protein K DEAD PF00270.29 KXG48248.1 - 5.1e-22 78.5 0.0 3.5e-21 75.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG48248.1 - 4e-18 65.8 0.2 6.6e-15 55.4 0.1 3.4 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RQC PF09382.10 KXG48248.1 - 2.1e-16 59.7 0.0 4.7e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 KXG48248.1 - 1.2e-15 58.0 7.5 3.9e-15 56.3 7.5 2.0 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 KXG48248.1 - 2e-09 37.3 0.0 6.5e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 HRDC domain ResIII PF04851.15 KXG48248.1 - 0.00014 21.9 0.0 0.00043 20.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4110 PF13422.6 KXG48249.1 - 2.4e-32 110.9 4.7 2.4e-32 110.9 4.7 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 KXG48249.1 - 3e-26 91.1 12.6 1.6e-06 28.0 0.0 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KXG48249.1 - 4.2e-25 87.5 13.9 1.7e-08 34.5 0.2 6.7 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KXG48249.1 - 1.4e-16 60.0 6.0 8.2e-06 25.7 0.1 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KXG48249.1 - 7.8e-15 54.2 5.1 0.00017 21.5 0.0 5.9 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 KXG48249.1 - 5.2e-14 51.9 5.3 0.00062 20.0 0.2 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KXG48249.1 - 4.1e-13 48.7 0.0 1.4e-05 24.6 0.0 4.6 4 0 0 4 4 4 4 Kelch motif LPD15 PF18828.1 KXG48249.1 - 0.086 12.7 0.3 0.086 12.7 0.3 2.3 3 0 0 3 3 3 0 Large polyvalent-protein-associated domain 15 PI3K_1B_p101 PF10486.9 KXG48249.1 - 6.6 4.4 7.7 12 3.5 7.7 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pyridoxal_deC PF00282.19 KXG48250.1 - 1.3e-25 89.9 0.0 1.9e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KXG48250.1 - 0.00075 18.9 0.0 0.00094 18.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KXG48250.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXG48250.1 - 0.022 13.9 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II SepSecS PF05889.13 KXG48250.1 - 0.033 12.9 0.0 0.1 11.3 0.0 1.7 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS MFS_1 PF07690.16 KXG48251.1 - 6.6e-34 117.4 41.6 2.3e-32 112.3 41.6 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG48251.1 - 1.1e-15 57.1 23.3 1.8e-15 56.4 23.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXG48251.1 - 5e-13 48.7 9.5 5e-13 48.7 9.5 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter Abhydrolase_1 PF00561.20 KXG48251.1 - 5.9e-13 49.0 0.0 1.7e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG48251.1 - 1.9e-07 30.6 0.0 3.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 MFS_3 PF05977.13 KXG48251.1 - 0.00092 17.7 3.4 0.00092 17.7 3.4 2.5 2 1 0 3 3 3 1 Transmembrane secretion effector OATP PF03137.20 KXG48251.1 - 0.0062 14.9 1.5 0.02 13.2 1.5 1.8 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S9 PF00326.21 KXG48251.1 - 0.039 13.4 0.0 0.14 11.6 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 KXG48251.1 - 0.088 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Peptidase_S28 PF05577.12 KXG48251.1 - 0.12 11.1 0.0 12 4.5 0.0 2.2 2 0 0 2 2 2 0 Serine carboxypeptidase S28 DUF21 PF01595.20 KXG48251.1 - 3.1 7.5 6.3 5.5 6.6 1.7 2.8 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Mon1 PF03164.14 KXG48252.1 - 8.8e-156 519.0 0.0 1e-155 518.8 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Dopey_N PF04118.14 KXG48253.1 - 2.6e-112 374.9 0.0 5.9e-112 373.7 0.0 1.6 1 0 0 1 1 1 1 Dopey, N-terminal Hpt PF01627.23 KXG48253.1 - 0.11 12.8 0.9 2.7 8.3 0.0 3.5 4 0 0 4 4 4 0 Hpt domain DivIC PF04977.15 KXG48254.1 - 0.034 13.9 0.2 0.04 13.7 0.2 1.2 1 0 0 1 1 1 0 Septum formation initiator GIT_CC PF16559.5 KXG48254.1 - 0.13 12.1 0.3 0.38 10.6 0.1 1.7 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor zf-HIT PF04438.16 KXG48255.1 - 4.7e-08 32.8 11.8 7.8e-08 32.1 11.8 1.4 1 0 0 1 1 1 1 HIT zinc finger Med3 PF11593.8 KXG48255.1 - 0.022 14.0 3.3 0.032 13.4 3.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MBOAT PF03062.19 KXG48256.1 - 9.8e-41 140.3 16.9 2.6e-34 119.1 4.2 2.4 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Cortexin PF11057.8 KXG48256.1 - 0.2 11.6 1.2 2.1 8.2 0.2 3.2 3 1 0 3 3 3 0 Cortexin of kidney AOX PF01786.17 KXG48257.1 - 1.6e-99 331.8 0.0 2.2e-99 331.4 0.0 1.2 1 0 0 1 1 1 1 Alternative oxidase CH PF00307.31 KXG48258.1 - 0.031 14.4 0.1 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 Calponin homology (CH) domain KAR9 PF08580.10 KXG48259.1 - 2.9e-230 766.4 6.1 2.9e-230 766.4 6.1 2.1 2 1 1 3 3 3 1 Yeast cortical protein KAR9 FlaC_arch PF05377.11 KXG48259.1 - 0.07 13.5 3.7 27 5.2 0.0 4.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 KXG48259.1 - 0.25 11.9 3.7 4.4 7.8 0.3 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Sec8_exocyst PF04048.14 KXG48259.1 - 0.35 10.7 2.9 15 5.5 0.2 3.0 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Prominin PF05478.11 KXG48259.1 - 7.4 4.4 7.3 2.8 5.8 0.7 2.6 3 0 0 3 3 3 0 Prominin Acetyltransf_1 PF00583.25 KXG48260.1 - 1.1e-06 28.9 0.0 1.4e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KXG48260.1 - 8.4e-06 26.5 0.0 1.3e-05 25.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXG48260.1 - 0.00019 21.8 0.0 0.00032 21.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXG48260.1 - 0.0033 17.6 0.0 0.0045 17.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG48260.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.7 KXG48260.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR_2 PF13233.6 KXG48261.1 - 5.2e-21 75.2 0.1 6.9e-21 74.8 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KXG48261.1 - 1.6e-10 40.9 0.0 2.4e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MTS PF05175.14 KXG48262.1 - 0.0024 17.4 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF4470 PF14737.6 KXG48263.1 - 6.8e-22 77.5 0.0 1.3e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KXG48263.1 - 1.3e-10 41.1 9.1 2.9e-10 40.1 9.1 1.6 1 0 0 1 1 1 1 MYND finger AD PF09793.9 KXG48264.1 - 6.9e-27 93.4 0.0 1.1e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain GTP_EFTU PF00009.27 KXG48265.1 - 1.5e-08 34.4 0.0 3.7e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXG48265.1 - 0.0019 18.2 0.3 1.5 8.7 0.2 2.6 2 0 0 2 2 2 2 RsgA GTPase LSM PF01423.22 KXG48266.1 - 1.3e-17 63.2 0.0 1.6e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXG48266.1 - 0.002 18.3 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain NUC153 PF08159.12 KXG48267.1 - 8.9e-12 44.6 0.8 2e-11 43.5 0.1 2.1 2 0 0 2 2 2 1 NUC153 domain WD40 PF00400.32 KXG48267.1 - 0.00053 20.7 0.1 31 5.7 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG48267.1 - 0.099 12.9 0.0 1.5 9.2 0.0 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Chorion_2 PF03964.15 KXG48267.1 - 0.59 11.0 5.8 1.9 9.4 5.8 1.9 1 0 0 1 1 1 0 Chorion family 2 Med13_C PF06333.12 KXG48268.1 - 3.5e-87 292.8 3.2 3.5e-87 292.8 3.2 2.4 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KXG48268.1 - 1.4e-69 234.9 1.9 2.5e-69 234.1 1.9 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KXG48268.1 - 5.7e-32 111.5 7.3 1.1e-18 67.9 0.1 3.7 3 1 1 4 4 4 2 MID domain of medPIWI Rsm1 PF08600.10 KXG48268.1 - 0.022 14.9 0.0 0.072 13.3 0.0 1.8 1 0 0 1 1 1 0 Rsm1-like RRM_1 PF00076.22 KXG48269.1 - 3.7e-16 58.7 0.0 7.4e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXG48269.1 - 0.099 12.8 0.2 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif 6PGD PF00393.19 KXG48270.1 - 9.9e-129 428.8 0.0 1.2e-128 428.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KXG48270.1 - 5.9e-50 169.5 0.0 8.5e-50 169.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXG48270.1 - 0.065 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PGK PF00162.19 KXG48270.1 - 0.24 10.3 0.0 0.38 9.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase p450 PF00067.22 KXG48271.1 - 1.1e-71 242.0 0.0 1.3e-71 241.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Get5_bdg PF16843.5 KXG48271.1 - 0.054 13.0 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein BAR PF03114.18 KXG48271.1 - 0.21 11.2 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 BAR domain RCC1 PF00415.18 KXG48272.1 - 1.1e-24 86.8 0.2 3.8e-06 27.4 0.0 6.7 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXG48272.1 - 4.7e-12 45.4 4.9 3.3e-08 33.1 0.1 3.3 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KXG48272.1 - 1.2e-11 44.8 0.0 1.3e-09 38.2 0.1 2.6 2 0 0 2 2 2 1 BTB/POZ domain Ank_4 PF13637.6 KXG48272.1 - 2.1e-10 40.9 0.1 5.7e-05 23.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG48272.1 - 4.7e-07 29.6 0.1 0.02 15.4 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KXG48272.1 - 2.7e-05 24.7 0.0 6.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXG48272.1 - 0.00027 21.2 0.0 0.5 10.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Dynamin_N PF00350.23 KXG48273.1 - 3.6e-29 102.0 0.2 8.3e-29 100.8 0.0 1.7 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KXG48273.1 - 1.1e-26 93.7 0.2 4.4e-19 68.8 0.0 2.2 1 1 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KXG48273.1 - 0.0011 19.0 0.0 0.64 10.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GED PF02212.18 KXG48273.1 - 0.0075 16.4 0.0 0.026 14.7 0.0 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain AAA_15 PF13175.6 KXG48273.1 - 0.015 15.0 0.0 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 KXG48273.1 - 0.062 13.7 0.1 0.51 10.7 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 KXG48273.1 - 0.082 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system LIP PF03583.14 KXG48274.1 - 1.1e-59 202.1 0.2 1.5e-59 201.7 0.2 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 KXG48274.1 - 1.3e-05 24.8 0.1 0.039 13.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KXG48274.1 - 0.027 14.0 0.3 0.18 11.3 0.1 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KXG48274.1 - 0.053 13.3 0.2 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KXG48274.1 - 0.053 12.8 0.1 0.15 11.3 0.0 1.8 3 0 0 3 3 3 0 Serine aminopeptidase, S33 ATG13 PF10033.9 KXG48275.1 - 1.4e-75 254.0 0.0 2.5e-75 253.3 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 HSD3 PF15244.6 KXG48275.1 - 1.6 8.1 6.5 2.7 7.4 6.5 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Ank_2 PF12796.7 KXG48276.1 - 0.025 15.2 0.0 0.046 14.3 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF4484 PF14831.6 KXG48277.1 - 0.037 14.1 1.5 7.2 6.6 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) PBP1_TM PF14812.6 KXG48277.1 - 9.1 6.7 8.0 7.5 7.0 3.5 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal U3_snoRNA_assoc PF08297.11 KXG48277.1 - 9.8 7.0 10.0 0.43 11.3 1.1 3.2 3 0 0 3 3 3 0 U3 snoRNA associated VHS PF00790.19 KXG48278.1 - 1.8e-39 134.8 0.9 1.7e-38 131.7 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KXG48278.1 - 5.2e-16 58.5 2.3 8.4e-16 57.9 2.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger GAT PF03127.14 KXG48278.1 - 2.4e-05 24.6 0.1 7.4e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 KXG48278.1 - 8.6e-05 22.2 20.1 0.012 15.5 2.9 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 KXG48278.1 - 0.06 13.6 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Npa1 PF11707.8 KXG48278.1 - 0.086 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal DZR PF12773.7 KXG48278.1 - 0.22 11.6 2.4 0.47 10.5 2.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KXG48278.1 - 0.34 10.9 2.0 0.8 9.7 2.0 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain UCH PF00443.29 KXG48279.1 - 4.9e-51 173.7 0.0 8.9e-51 172.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXG48279.1 - 1.9e-17 63.9 0.2 8.9e-15 55.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 KXG48279.1 - 5.7e-06 26.5 0.0 1.7e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.20 KXG48279.1 - 1.3e-05 25.6 0.0 3.6e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Cyt-b5 PF00173.28 KXG48280.1 - 4.8e-17 61.9 0.3 2.2e-08 34.1 0.0 2.5 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DUF4366 PF14283.6 KXG48280.1 - 0.073 13.1 0.1 2.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) KH_1 PF00013.29 KXG48281.1 - 9.6e-92 300.8 21.1 3.1e-12 46.1 0.1 13.3 13 1 0 13 13 13 9 KH domain SLS PF14611.6 KXG48281.1 - 1.8e-12 47.6 4.1 0.76 9.6 0.0 8.6 6 3 1 7 7 7 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KXG48281.1 - 1.6e-11 43.9 22.4 0.0024 17.6 0.2 7.3 6 1 1 7 7 7 5 KH domain KH_4 PF13083.6 KXG48281.1 - 0.0042 16.9 6.2 11 5.9 0.1 5.3 5 0 0 5 5 5 2 KH domain RL10P_insert PF17777.1 KXG48281.1 - 0.04 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Insertion domain in 60S ribosomal protein L10P DUF2570 PF10828.8 KXG48281.1 - 0.043 13.6 0.7 11 5.9 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) LeuA_dimer PF08502.10 KXG48281.1 - 0.065 13.1 0.3 4.5 7.2 0.0 3.1 3 0 0 3 3 3 0 LeuA allosteric (dimerisation) domain Acylphosphatase PF00708.18 KXG48281.1 - 0.14 12.6 2.1 1.4 9.3 0.2 3.4 3 0 0 3 3 3 0 Acylphosphatase KH_5 PF13184.6 KXG48281.1 - 0.21 11.7 11.0 44 4.2 0.1 6.2 7 0 0 7 7 7 0 NusA-like KH domain Glyco_hydro_43 PF04616.14 KXG48282.1 - 8.5e-33 113.9 7.6 1.1e-32 113.5 7.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 SprB PF13573.6 KXG48282.1 - 0.27 11.0 2.3 2.4 8.0 0.2 2.5 2 0 0 2 2 2 0 SprB repeat Pkinase PF00069.25 KXG48284.1 - 8.2e-71 238.4 0.0 1.2e-70 237.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48284.1 - 3.1e-44 151.2 0.0 5.1e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KXG48284.1 - 6.4e-22 77.7 0.1 1.7e-21 76.3 0.1 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KXG48284.1 - 3.7e-07 29.3 0.3 1.3e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KXG48284.1 - 1.1e-06 28.2 0.0 2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXG48284.1 - 0.018 14.0 0.4 0.11 11.5 0.4 2.1 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KXG48284.1 - 0.06 13.3 5.1 0.43 10.4 0.1 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KXG48284.1 - 0.086 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.12 KXG48284.1 - 0.18 11.5 0.0 0.42 10.2 0.0 1.6 1 0 0 1 1 1 0 DSHCT (NUC185) domain VHS PF00790.19 KXG48285.1 - 1e-35 122.7 1.1 1.8e-35 121.9 1.1 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KXG48285.1 - 1.9e-16 59.4 0.1 5.7e-16 57.9 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXG48285.1 - 1.7e-14 53.4 0.1 3.2e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXG48285.1 - 7.4e-14 51.2 0.0 1.5e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KXG48285.1 - 9.9e-10 38.6 1.7 9.9e-10 38.6 1.7 1.9 2 0 0 2 2 2 1 GAT domain Hrs_helical PF12210.8 KXG48285.1 - 0.055 14.0 0.2 0.19 12.3 0.2 1.9 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate UIM PF02809.20 KXG48285.1 - 0.11 12.5 3.3 0.27 11.2 3.3 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif Pkinase PF00069.25 KXG48286.1 - 1.5e-16 60.6 0.0 1.9e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48286.1 - 5.6e-09 35.7 0.1 9.6e-09 34.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXG48286.1 - 3.2e-05 24.0 0.2 0.0027 17.7 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXG48286.1 - 7e-05 22.5 0.1 0.00012 21.7 0.1 1.4 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 KXG48286.1 - 0.00023 20.6 0.0 0.00038 19.9 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KXG48286.1 - 0.012 15.3 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase LOR PF04525.12 KXG48287.1 - 4.4e-09 36.2 0.0 9.7e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 LURP-one-related NmrA PF05368.13 KXG48288.1 - 2.2e-60 204.2 0.1 2.7e-60 203.8 0.1 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG48288.1 - 5.3e-17 62.3 0.2 9.4e-17 61.5 0.1 1.4 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXG48288.1 - 1.3e-05 24.3 0.0 1.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXG48288.1 - 5.7e-05 22.7 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXG48288.1 - 0.0018 18.5 0.1 0.0027 18.0 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KXG48288.1 - 0.07 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ADH_zinc_N PF00107.26 KXG48288.1 - 0.079 12.9 0.5 0.44 10.5 0.2 2.3 3 0 0 3 3 3 0 Zinc-binding dehydrogenase GATase PF00117.28 KXG48289.1 - 0.0029 17.4 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Fungal_trans PF04082.18 KXG48290.1 - 1e-13 51.0 2.7 2.1e-12 46.7 2.7 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain RNase_P_pop3 PF08228.11 KXG48290.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 UCH_1 PF13423.6 KXG48291.1 - 1.7e-94 317.0 0.1 2.3e-94 316.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KXG48291.1 - 2.1e-15 57.6 0.0 9.6e-15 55.5 0.0 2.1 2 1 1 3 3 3 1 Exonuclease UCH PF00443.29 KXG48291.1 - 9.6e-05 22.0 0.0 0.00087 18.8 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Fungal_trans PF04082.18 KXG48292.1 - 1.7e-10 40.4 0.4 3.1e-10 39.6 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sporozoite_P67 PF05642.11 KXG48293.1 - 0.13 10.4 1.8 0.12 10.4 1.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen P33MONOX PF15302.6 KXG48293.1 - 0.68 9.6 5.3 0.91 9.2 5.3 1.1 1 0 0 1 1 1 0 P33 mono-oxygenase TALPID3 PF15324.6 KXG48293.1 - 0.97 7.0 4.8 1.1 6.9 4.8 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Glyoxalase PF00903.25 KXG48294.1 - 5.4e-15 55.7 4.0 2.8e-13 50.2 1.6 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.19 KXG48295.1 - 8.2e-38 130.5 0.0 2e-22 79.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXG48295.1 - 1.9e-05 24.8 0.2 4.8e-05 23.5 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXG48295.1 - 8.7e-05 21.9 0.3 0.00016 21.0 0.2 1.5 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KXG48295.1 - 0.0015 17.3 0.2 0.0065 15.2 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KXG48295.1 - 0.0025 17.1 0.9 0.0038 16.5 0.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXG48295.1 - 0.0099 15.0 1.0 0.017 14.2 0.3 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXG48295.1 - 0.017 14.3 0.8 0.026 13.6 0.8 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KXG48295.1 - 0.024 13.9 0.2 0.04 13.2 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXG48295.1 - 0.046 14.0 0.4 0.12 12.6 0.2 1.8 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.27 KXG48295.1 - 0.085 13.4 0.3 0.18 12.4 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXG48295.1 - 0.14 11.4 0.4 0.23 10.8 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAA_hydrolase PF01557.18 KXG48296.1 - 5.9e-55 186.3 0.0 7.6e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GTP_EFTU PF00009.27 KXG48297.1 - 1.4e-48 165.0 0.0 2.2e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MFS_1 PF07690.16 KXG48297.1 - 1.2e-37 129.7 26.9 6.9e-37 127.2 28.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily HBS1_N PF08938.10 KXG48297.1 - 3.9e-20 71.9 3.8 7e-20 71.1 3.8 1.4 1 0 0 1 1 1 1 HBS1 N-terminus Sugar_tr PF00083.24 KXG48297.1 - 1.4e-11 44.0 2.9 1.4e-11 44.0 2.9 2.6 2 0 0 2 2 2 1 Sugar (and other) transporter GTP_EFTU_D2 PF03144.25 KXG48297.1 - 4.4e-10 39.8 0.0 9.3e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KXG48297.1 - 5.3e-08 33.2 0.0 3.5e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KXG48297.1 - 2.7e-07 30.7 0.0 4.6e-06 26.7 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXG48297.1 - 0.001 18.4 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KXG48297.1 - 0.0011 18.4 0.1 0.062 12.7 0.1 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit TRI12 PF06609.13 KXG48297.1 - 0.0026 16.3 2.5 0.0043 15.5 2.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Arf PF00025.21 KXG48297.1 - 0.015 14.8 0.0 3.8 6.9 0.0 2.3 1 1 1 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 KXG48297.1 - 0.018 15.2 0.1 3.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Acyltransf_C PF16076.5 KXG48297.1 - 0.027 14.6 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Acyltransferase C-terminus FeoB_N PF02421.18 KXG48297.1 - 0.067 12.7 0.5 0.93 9.0 0.2 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.18 KXG48297.1 - 0.13 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Septin PBP1_TM PF14812.6 KXG48297.1 - 0.17 12.3 0.3 0.45 10.9 0.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HSP70 PF00012.20 KXG48298.1 - 5.1e-259 860.5 16.8 5.8e-259 860.3 16.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXG48298.1 - 4.9e-17 61.7 1.6 8.5e-16 57.7 0.4 2.2 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 KXG48298.1 - 0.0022 17.0 0.8 0.013 14.6 0.3 2.0 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FIVAR PF07554.13 KXG48298.1 - 0.21 12.4 7.6 23 5.8 0.8 4.3 3 1 0 3 3 3 0 FIVAR domain Hydantoinase_A PF01968.18 KXG48298.1 - 0.28 10.4 6.5 0.8 8.9 0.1 3.6 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase CCDC50_N PF15295.6 KXG48298.1 - 0.46 10.6 6.2 0.66 10.1 0.9 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus FtsA PF14450.6 KXG48298.1 - 0.7 10.3 8.3 16 6.0 0.3 3.7 3 2 0 3 3 3 0 Cell division protein FtsA GLE1 PF07817.13 KXG48298.1 - 1.3 8.2 3.7 3.1 7.0 0.0 2.9 3 1 0 3 3 3 0 GLE1-like protein DUF4845 PF16137.5 KXG48298.1 - 1.4 9.8 4.4 18 6.3 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4845) Haem_degrading PF03928.14 KXG48299.1 - 6.6e-36 123.0 0.5 8.8e-36 122.6 0.5 1.2 1 0 0 1 1 1 1 Haem-degrading Pneumo_NS1 PF03438.13 KXG48299.1 - 0.034 14.3 0.0 0.051 13.7 0.0 1.2 1 0 0 1 1 1 0 Pneumovirus NS1 protein ADH_zinc_N PF00107.26 KXG48301.1 - 4.9e-25 88.0 0.4 7.8e-25 87.4 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG48301.1 - 1.8e-21 76.1 0.3 3.2e-21 75.3 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXG48301.1 - 1.9e-07 32.2 0.0 3.9e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPALS PF18178.1 KXG48301.1 - 0.14 11.6 0.4 0.21 11.0 0.4 1.2 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family Arylsulfotran_2 PF14269.6 KXG48303.1 - 8.4e-111 370.1 8.1 1.1e-110 369.7 8.1 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Bys1 PF04681.12 KXG48304.1 - 1.9e-09 37.6 0.0 2.6e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Fe-ADH PF00465.19 KXG48305.1 - 1.6e-102 343.1 0.1 2e-102 342.7 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KXG48305.1 - 3.8e-15 56.3 0.0 2.1e-11 44.0 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 KXG48305.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Fungal_trans_2 PF11951.8 KXG48306.1 - 0.0031 16.4 0.1 0.0076 15.1 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain HR1 PF02185.16 KXG48306.1 - 0.31 11.2 1.3 2 8.6 0.1 2.1 2 0 0 2 2 2 0 Hr1 repeat 2-Hacid_dh_C PF02826.19 KXG48307.1 - 1.5e-55 187.3 0.1 9.9e-55 184.6 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXG48307.1 - 2.1e-36 124.5 0.3 1.2e-35 122.1 0.1 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 KXG48307.1 - 0.0023 18.4 0.0 0.008 16.7 0.0 2.0 1 0 0 1 1 1 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.21 KXG48307.1 - 0.0059 16.7 0.0 0.045 13.8 0.0 2.2 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 KXG48307.1 - 0.012 14.9 0.9 0.043 13.1 0.9 1.9 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 KXG48307.1 - 0.024 14.2 0.0 0.082 12.5 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain HALZ PF02183.18 KXG48307.1 - 0.047 13.9 4.0 0.18 12.1 4.0 2.1 1 0 0 1 1 1 0 Homeobox associated leucine zipper ACT PF01842.25 KXG48307.1 - 0.06 13.1 0.3 0.56 10.0 0.0 2.7 3 0 0 3 3 3 0 ACT domain NAD_binding_2 PF03446.15 KXG48307.1 - 0.078 13.1 0.2 0.35 11.0 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase APG6_N PF17675.1 KXG48307.1 - 0.14 12.7 14.7 0.28 11.7 14.7 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region Serine_rich PF08824.10 KXG48307.1 - 0.15 12.0 0.8 0.36 10.8 0.8 1.6 1 0 0 1 1 1 0 Serine rich protein interaction domain zf-C2H2_2 PF12756.7 KXG48308.1 - 1.3e-36 125.0 22.3 2.8e-31 107.8 6.1 3.3 2 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KXG48308.1 - 4.7e-06 26.8 7.6 4.7e-06 26.8 7.6 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXG48308.1 - 3.2e-05 24.2 6.0 3.2e-05 24.2 6.0 3.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KXG48308.1 - 0.087 13.7 18.5 1.7 9.7 1.0 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger Rpr2 PF04032.16 KXG48308.1 - 0.14 12.5 2.8 2.5 8.4 0.2 3.0 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2 PF00096.26 KXG48308.1 - 0.21 12.1 27.7 0.057 13.9 3.2 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KXG48308.1 - 2.6 8.1 12.2 4.7 7.3 0.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger CEBP_ZZ PF16366.5 KXG48308.1 - 5.9 7.2 11.3 0.23 11.7 0.3 3.4 3 0 0 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain HECT PF00632.25 KXG48309.1 - 2.5e-70 237.4 0.0 5e-70 236.4 0.0 1.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KXG48309.1 - 1.8e-20 72.9 1.9 3.7e-20 71.9 1.9 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A His_Phos_1 PF00300.22 KXG48310.1 - 1.6e-17 63.9 0.3 2.9e-17 63.0 0.1 1.5 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF21 PF01595.20 KXG48312.1 - 1.8e-31 109.2 0.0 2.9e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KXG48312.1 - 0.00024 21.5 0.6 0.037 14.5 0.0 3.3 3 0 0 3 3 3 2 CBS domain HALZ PF02183.18 KXG48313.1 - 0.01 16.0 3.3 0.01 16.0 3.3 5.0 6 0 0 6 6 6 0 Homeobox associated leucine zipper HCV_NS4a PF01006.20 KXG48313.1 - 0.02 14.7 1.0 0.035 13.9 1.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a UPF0242 PF06785.11 KXG48313.1 - 0.3 11.2 38.3 0.12 12.5 0.2 4.1 2 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus GIT_CC PF16559.5 KXG48313.1 - 0.64 9.9 7.6 8.2 6.4 0.6 4.0 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fungal_TACC PF12709.7 KXG48313.1 - 0.86 10.1 21.6 1.3 9.5 1.0 5.6 3 1 3 6 6 6 0 Fungal Transforming acidic coiled-coil (TACC) proteins YabA PF06156.13 KXG48313.1 - 4 8.1 29.8 0.76 10.4 2.3 4.9 3 2 2 5 5 5 0 Initiation control protein YabA HAP1_N PF04849.13 KXG48313.1 - 9.8 5.3 41.4 0.3 10.2 8.1 4.7 2 2 3 5 5 5 0 HAP1 N-terminal conserved region AhpC-TSA PF00578.21 KXG48314.1 - 6.7e-30 103.5 0.0 9.4e-30 103.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXG48314.1 - 6.7e-14 51.8 0.0 8.6e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KXG48314.1 - 4.4e-13 48.8 0.3 6.9e-13 48.2 0.3 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Glyco_hydro_3_C PF01915.22 KXG48315.1 - 1.2e-47 162.5 0.0 3.7e-47 160.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXG48315.1 - 1.9e-33 116.2 0.0 3.6e-33 115.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXG48315.1 - 9.6e-20 70.5 0.2 1.6e-19 69.8 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.16 KXG48316.1 - 3.9e-43 147.7 62.5 4e-43 147.7 58.5 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG48316.1 - 1.5e-15 57.1 31.0 6.1e-15 55.0 15.4 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KXG48316.1 - 1.2e-12 47.0 29.7 2.5e-12 46.0 29.5 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_25 PF13649.6 KXG48316.1 - 2e-09 38.0 0.0 6e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG48316.1 - 3.1e-07 31.1 0.0 5.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG48316.1 - 4.8e-07 29.7 0.0 8.3e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG48316.1 - 0.0002 22.0 0.0 0.0004 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG48316.1 - 0.00044 20.1 0.0 0.00074 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_M20 PF01546.28 KXG48317.1 - 7.2e-24 84.6 0.0 9.8e-22 77.7 0.0 2.4 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXG48317.1 - 2e-06 27.7 0.0 3.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXG48317.1 - 0.00014 21.6 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 WD40 PF00400.32 KXG48317.1 - 0.0054 17.5 16.0 0.13 13.2 0.2 5.4 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG48317.1 - 0.053 13.8 0.1 2.4 8.5 0.1 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TraQ PF09679.10 KXG48318.1 - 0.015 15.2 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) PT PF04886.12 KXG48318.1 - 5.2 6.7 7.3 2.3 7.8 3.7 2.2 2 0 0 2 2 2 0 PT repeat CENP-F_N PF10481.9 KXG48318.1 - 9.3 5.8 11.5 4.3 6.9 0.0 2.5 3 0 0 3 3 3 0 Cenp-F N-terminal domain FAD_binding_3 PF01494.19 KXG48319.1 - 3.6e-25 89.0 0.4 6.3e-25 88.2 0.4 1.3 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KXG48319.1 - 1.8e-05 24.0 7.6 1.9e-05 24.0 4.4 2.2 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG48319.1 - 2.1e-05 23.9 1.9 0.00014 21.2 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXG48319.1 - 2.3e-05 23.6 0.9 5.3e-05 22.4 0.9 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXG48319.1 - 3.5e-05 23.9 0.8 9.5e-05 22.6 0.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXG48319.1 - 0.00013 22.4 0.5 0.00099 19.6 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG48319.1 - 0.00013 21.6 8.7 0.016 14.8 5.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KXG48319.1 - 0.00019 20.7 1.8 0.00032 20.0 1.8 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KXG48319.1 - 0.00034 19.6 3.0 0.02 13.7 0.6 2.8 2 1 1 3 3 3 2 Tryptophan halogenase GIDA PF01134.22 KXG48319.1 - 0.00087 18.5 1.2 0.0014 17.8 1.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXG48319.1 - 0.00087 18.7 3.0 0.0016 17.8 3.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KXG48319.1 - 0.0019 17.6 1.3 0.69 9.1 0.2 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KXG48319.1 - 0.0028 16.4 3.4 0.0028 16.4 3.4 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KXG48319.1 - 0.14 11.3 0.3 0.31 10.3 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Arginosuc_synth PF00764.19 KXG48320.1 - 3.9e-158 526.8 0.0 4.5e-158 526.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KXG48320.1 - 0.0067 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KXG48320.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Transket_pyr PF02779.24 KXG48321.1 - 6.9e-43 146.4 0.0 1.2e-42 145.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXG48321.1 - 1.3e-32 112.3 0.0 3.1e-32 111.1 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KXG48321.1 - 0.14 12.5 0.1 0.46 10.8 0.0 1.9 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II NmrA PF05368.13 KXG48322.1 - 1.5e-23 83.6 0.0 2.1e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG48322.1 - 1.1e-19 71.0 0.0 1.5e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXG48322.1 - 3.2e-07 30.1 0.2 1e-06 28.4 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXG48322.1 - 8.6e-06 26.0 0.2 3.4e-05 24.1 0.1 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KXG48322.1 - 0.00068 19.7 0.4 0.004 17.3 0.1 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 KXG48322.1 - 0.00083 19.4 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KXG48322.1 - 0.02 15.5 0.0 0.046 14.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 KXG48322.1 - 0.023 13.7 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.19 KXG48322.1 - 0.039 13.3 0.2 0.08 12.3 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KXG48322.1 - 0.048 12.8 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein RmlD_sub_bind PF04321.17 KXG48322.1 - 0.059 12.5 0.1 0.091 11.8 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 KXG48322.1 - 0.082 12.4 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.24 KXG48322.1 - 0.11 12.9 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF572 PF04502.13 KXG48323.1 - 3.9e-68 230.5 0.8 4.4e-68 230.4 0.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Filament PF00038.21 KXG48324.1 - 0.00039 20.1 15.6 0.00039 20.1 15.6 7.6 1 1 4 7 7 7 5 Intermediate filament protein GAS PF13851.6 KXG48324.1 - 0.0025 17.2 10.4 0.0025 17.2 10.4 8.7 1 1 6 8 8 8 3 Growth-arrest specific micro-tubule binding PKcGMP_CC PF16808.5 KXG48324.1 - 0.026 14.4 0.4 0.026 14.4 0.4 6.8 8 0 0 8 8 8 0 Coiled-coil N-terminus of cGMP-dependent protein kinase RVT_N PF13655.6 KXG48324.1 - 0.16 12.2 7.2 2.1 8.7 1.0 4.3 4 0 0 4 4 4 0 N-terminal domain of reverse transcriptase Pox_A_type_inc PF04508.12 KXG48324.1 - 0.19 11.7 0.0 0.19 11.7 0.0 6.5 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat Spc7 PF08317.11 KXG48324.1 - 2 7.2 173.1 0.081 11.8 22.3 9.1 1 1 6 8 8 8 0 Spc7 kinetochore protein PTPA PF03095.15 KXG48326.1 - 5.8e-115 383.9 0.0 6.7e-115 383.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Methyltranf_PUA PF13636.6 KXG48326.1 - 0.027 14.5 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA-binding PUA-like domain of methyltransferase RsmF Zip PF02535.22 KXG48327.1 - 2.7e-55 187.9 0.8 5.5e-55 186.9 0.8 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter DUF1282 PF06930.12 KXG48327.1 - 0.062 13.1 0.4 0.062 13.1 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) HC2 PF07382.11 KXG48328.1 - 0.072 13.2 93.2 0.049 13.7 57.3 2.1 1 1 1 2 2 2 0 Histone H1-like nucleoprotein HC2 IMS PF00817.20 KXG48329.1 - 2e-42 144.7 0.0 3.6e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 KXG48329.1 - 1.3e-21 76.8 0.1 2.5e-21 75.9 0.1 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 KXG48329.1 - 3.3e-14 53.6 0.0 7.8e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 KXG48329.1 - 1.5e-11 43.3 9.3 1.3e-06 27.6 1.5 4.4 3 0 0 3 3 3 3 Ubiquitin binding region BRCT_2 PF16589.5 KXG48329.1 - 2.2e-09 37.6 0.0 4.6e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 KXG48329.1 - 2.1e-05 24.6 0.0 6.4e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif BRCT PF00533.26 KXG48329.1 - 0.00019 21.7 0.0 0.00067 20.0 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KXG48329.1 - 0.00045 20.5 0.0 0.00095 19.4 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain mCpol PF18182.1 KXG48329.1 - 0.0038 17.5 0.0 0.008 16.5 0.0 1.5 1 0 0 1 1 1 1 minimal CRISPR polymerase domain HHH_5 PF14520.6 KXG48329.1 - 0.0073 16.9 0.1 0.023 15.3 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cdd1 PF11731.8 KXG48329.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus PTCB-BRCT PF12738.7 KXG48329.1 - 0.017 15.0 0.0 0.079 12.9 0.0 2.2 2 0 0 2 2 2 0 twin BRCT domain DUF1805 PF08827.11 KXG48329.1 - 0.14 12.5 0.0 0.4 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) MgtE_N PF03448.17 KXG48329.1 - 0.16 12.6 1.6 24 5.6 0.3 3.9 3 0 0 3 3 3 0 MgtE intracellular N domain FKBP_C PF00254.28 KXG48330.1 - 3.6e-32 110.5 0.0 1.3e-31 108.7 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KXG48330.1 - 8.8e-30 103.4 5.3 8.8e-30 103.4 5.3 2.8 2 2 0 2 2 2 1 Nucleoplasmin-like domain zf-RING_2 PF13639.6 KXG48331.1 - 6.3e-12 45.6 9.1 6.3e-12 45.6 9.1 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KXG48331.1 - 7.8e-11 41.5 3.3 1.6e-10 40.5 3.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXG48331.1 - 3e-09 36.6 9.2 3e-09 36.6 9.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXG48331.1 - 7.4e-08 32.6 10.7 1.4e-07 31.7 7.7 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KXG48331.1 - 2.5e-07 30.5 4.2 4.3e-07 29.7 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXG48331.1 - 6.4e-06 25.9 8.1 1.2e-05 25.1 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXG48331.1 - 3.2e-05 23.9 1.8 3.2e-05 23.9 1.8 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXG48331.1 - 7e-05 22.7 5.8 0.00012 21.9 5.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-HC5HC2H PF13771.6 KXG48331.1 - 0.00092 19.4 5.1 0.13 12.5 0.3 2.2 1 1 1 2 2 2 2 PHD-like zinc-binding domain Prok-RING_4 PF14447.6 KXG48331.1 - 0.001 18.9 6.7 0.0017 18.2 6.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-HC5HC2H_2 PF13832.6 KXG48331.1 - 0.0041 17.3 5.6 0.34 11.1 0.5 2.2 1 1 1 2 2 2 2 PHD-zinc-finger like domain zf-ANAPC11 PF12861.7 KXG48331.1 - 0.018 15.1 11.2 0.041 13.9 7.5 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KXG48331.1 - 0.081 12.7 3.4 0.15 11.9 3.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KXG48331.1 - 0.084 13.0 3.7 0.21 11.8 3.7 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KXG48331.1 - 0.085 12.5 8.5 0.16 11.6 8.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KXG48331.1 - 0.81 10.1 9.6 0.64 10.4 7.3 1.9 2 0 0 2 2 2 0 RING-like domain RINGv PF12906.7 KXG48331.1 - 2.3 8.4 7.8 6.8 6.9 7.8 1.8 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 KXG48331.1 - 5.8 6.9 10.2 0.76 9.7 6.0 1.8 2 0 0 2 2 2 0 PHD-finger MAGUK_N_PEST PF10608.9 KXG48333.1 - 0.045 14.2 7.0 0.96 9.9 7.0 2.1 1 1 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK Peptidase_M3 PF01432.20 KXG48334.1 - 5.3e-117 391.9 0.0 8.2e-117 391.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 KXG48334.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Effector protein DUF2644 PF10841.8 KXG48334.1 - 0.19 12.0 0.1 0.49 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) ApoO PF09769.9 KXG48335.1 - 3.7e-40 136.9 0.2 2.3e-39 134.3 0.1 2.1 2 0 0 2 2 2 1 Apolipoprotein O GRASP55_65 PF04495.14 KXG48336.1 - 4.6e-41 140.4 0.0 6.2e-40 136.7 0.0 2.0 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KXG48336.1 - 0.001 18.8 0.0 0.34 10.8 0.0 2.8 2 0 0 2 2 2 2 PDZ domain Methyltransf_15 PF09445.10 KXG48337.1 - 7.6e-52 175.2 0.0 9.5e-52 174.9 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 KXG48337.1 - 3.5e-10 40.0 0.0 4.6e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 KXG48337.1 - 3.2e-07 30.1 0.0 4.4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 KXG48337.1 - 2.6e-06 27.3 0.0 4.4e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 KXG48337.1 - 0.00047 19.5 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_31 PF13847.6 KXG48337.1 - 0.00065 19.5 0.0 0.00084 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KXG48337.1 - 0.0014 18.6 0.0 0.0028 17.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG48337.1 - 0.0072 17.0 0.0 0.013 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KXG48337.1 - 0.016 14.4 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_5 PF01795.19 KXG48337.1 - 0.031 13.8 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family Methyltransf_11 PF08241.12 KXG48337.1 - 0.031 14.9 0.0 0.054 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF3591 PF12157.8 KXG48338.1 - 8e-176 585.0 0.3 1.1e-175 584.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 KXG48338.1 - 0.0053 16.8 0.7 0.0088 16.1 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KXG48338.1 - 0.0067 16.2 1.2 0.016 15.0 1.2 1.7 1 0 0 1 1 1 1 Zinc knuckle Pkinase PF00069.25 KXG48339.1 - 9.4e-48 162.9 0.3 8.9e-26 90.8 0.0 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48339.1 - 2.8e-20 72.7 0.0 9.3e-12 44.8 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KXG48339.1 - 0.0031 17.5 0.4 0.0091 15.9 0.3 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXG48339.1 - 0.084 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Orbi_NS1 PF01718.16 KXG48339.1 - 0.14 10.6 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein AAA PF00004.29 KXG48340.1 - 1.5e-17 64.3 0.0 3.4e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXG48340.1 - 0.00099 19.4 0.6 0.012 15.9 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KXG48340.1 - 0.0015 18.9 0.0 0.006 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KXG48340.1 - 0.042 13.8 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KXG48340.1 - 0.046 13.4 0.1 0.081 12.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXG48340.1 - 0.098 13.0 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 KXG48341.1 - 3.2e-31 108.3 0.9 1e-30 106.7 0.9 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF927 PF06048.11 KXG48341.1 - 0.2 11.2 0.0 0.43 10.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF927) MSC PF09402.10 KXG48342.1 - 1.4e-107 360.1 0.0 1.9e-107 359.7 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KXG48342.1 - 1.4e-16 59.9 0.0 2.7e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain PP2C PF00481.21 KXG48343.1 - 9.2e-53 179.5 0.0 1.4e-52 178.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 KXG48343.1 - 7.1e-35 118.5 62.0 0.00012 22.4 1.1 12.6 8 2 6 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXG48343.1 - 2.8e-34 116.7 62.1 3.2e-07 30.0 3.8 11.1 5 3 7 13 13 13 11 Leucine rich repeat Guanylate_cyc PF00211.20 KXG48343.1 - 4.7e-26 91.5 0.0 9.2e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.33 KXG48343.1 - 1.7e-06 27.8 50.9 8.7 7.3 0.3 15.6 14 3 0 14 14 14 3 Leucine Rich Repeat LRR_9 PF14580.6 KXG48343.1 - 3e-06 26.8 13.4 0.0061 16.1 0.1 4.4 2 1 2 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.6 KXG48343.1 - 1.6e-05 24.9 4.4 0.57 10.1 0.2 4.6 3 2 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) Ad_cyc_g-alpha PF08509.11 KXG48343.1 - 0.001 18.7 0.2 0.0037 16.9 0.2 2.0 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain Glyco_hydro_16 PF00722.21 KXG48344.1 - 7e-47 159.2 4.2 7e-47 159.2 4.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 F-box-like PF12937.7 KXG48345.1 - 0.01 15.7 0.1 0.022 14.7 0.1 1.6 1 0 0 1 1 1 0 F-box-like bZIP_1 PF00170.21 KXG48346.1 - 1.8e-05 24.7 1.9 4.5e-05 23.5 1.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor DASH_Dad3 PF08656.10 KXG48346.1 - 0.054 13.6 0.2 0.18 11.9 0.1 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF4988 PF16378.5 KXG48346.1 - 0.087 12.5 0.4 0.22 11.2 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function Aminotran_5 PF00266.19 KXG48347.1 - 1.3e-14 54.0 0.0 4.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXG48347.1 - 9.8e-05 21.7 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II cIII PF08134.11 KXG48347.1 - 0.021 14.6 0.1 0.045 13.5 0.1 1.5 1 0 0 1 1 1 0 cIII protein family Pro_CA PF00484.19 KXG48348.1 - 1.1e-12 48.5 0.5 4.9e-12 46.4 0.5 1.9 1 1 0 1 1 1 1 Carbonic anhydrase LEH PF07858.12 KXG48348.1 - 0.072 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain Fis1_TPR_C PF14853.6 KXG48349.1 - 3.1e-25 88.0 0.5 4.9e-25 87.3 0.5 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KXG48349.1 - 2.7e-16 58.9 0.1 4.4e-16 58.2 0.1 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KXG48349.1 - 0.013 15.6 1.4 0.013 15.6 1.4 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Spc24 PF08286.11 KXG48350.1 - 2.4e-37 127.4 1.4 5.1e-36 123.1 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.20 KXG48350.1 - 0.015 15.3 2.1 2.5 8.1 1.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit CLZ PF16526.5 KXG48350.1 - 0.066 13.6 8.4 1.4 9.3 1.5 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels APG6_N PF17675.1 KXG48350.1 - 0.077 13.5 10.7 0.11 13.1 10.7 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4795 PF16043.5 KXG48350.1 - 0.09 12.4 3.8 0.25 10.9 3.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4559 PF15112.6 KXG48350.1 - 0.11 12.2 1.5 0.14 11.9 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) TPR_MLP1_2 PF07926.12 KXG48350.1 - 0.33 11.0 11.2 0.19 11.8 2.6 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DMPK_coil PF08826.10 KXG48350.1 - 0.49 10.6 9.5 1 9.5 0.9 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like FlaC_arch PF05377.11 KXG48350.1 - 0.65 10.4 4.8 16 6.0 0.1 2.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 KXG48350.1 - 0.72 10.5 7.8 0.86 10.3 0.8 2.5 2 1 0 2 2 2 0 SlyX XhlA PF10779.9 KXG48350.1 - 3.3 8.0 7.2 6.5 7.0 1.0 2.2 2 0 0 2 2 2 0 Haemolysin XhlA DUF2034 PF10356.9 KXG48351.1 - 7.5e-41 139.6 0.0 1.1e-25 90.2 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KXG48351.1 - 1.2e-07 31.8 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.8 KXG48352.1 - 1.3e-58 197.3 5.4 2.6e-57 193.1 5.4 1.9 1 1 0 1 1 1 1 Subunit 21 of Mediator complex DUF4455 PF14643.6 KXG48352.1 - 0.0045 15.7 0.4 0.0064 15.2 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) APG6_N PF17675.1 KXG48352.1 - 0.005 17.4 1.2 0.02 15.4 1.8 1.6 2 0 0 2 2 2 1 Apg6 coiled-coil region DUF4515 PF14988.6 KXG48352.1 - 0.018 14.9 1.2 0.029 14.2 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Med9 PF07544.13 KXG48352.1 - 0.031 14.3 1.2 0.15 12.2 1.1 2.1 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 EzrA PF06160.12 KXG48352.1 - 0.092 10.9 0.4 0.12 10.5 0.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Dzip-like_N PF13815.6 KXG48352.1 - 0.2 11.6 1.1 0.34 10.9 1.1 1.3 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal SNF2_N PF00176.23 KXG48353.1 - 5.7e-63 212.8 0.0 8.8e-63 212.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXG48353.1 - 2.4e-09 37.5 0.0 8.7e-09 35.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXG48353.1 - 8.2e-05 22.4 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXG48353.1 - 0.0014 18.7 0.0 0.0034 17.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 KXG48353.1 - 0.054 13.4 7.5 0.016 15.1 3.5 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 MCPVI PF02993.14 KXG48353.1 - 0.074 12.9 1.1 0.34 10.7 1.0 2.1 2 0 0 2 2 2 0 Minor capsid protein VI zf-RING_5 PF14634.6 KXG48353.1 - 0.65 10.0 5.5 1.2 9.2 5.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KXG48353.1 - 1.8 8.9 6.8 4.4 7.7 6.8 1.7 1 0 0 1 1 1 0 Ring finger domain PI3_PI4_kinase PF00454.27 KXG48354.1 - 5.4e-44 150.9 0.0 7.6e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GATA PF00320.27 KXG48355.1 - 1.5e-15 56.5 2.6 2.5e-15 55.8 2.6 1.4 1 0 0 1 1 1 1 GATA zinc finger Pox_A_type_inc PF04508.12 KXG48355.1 - 0.00016 21.4 2.3 0.1 12.5 0.5 3.4 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat CENP-F_N PF10481.9 KXG48355.1 - 0.0066 16.1 1.6 0.087 12.4 0.0 2.1 1 1 1 2 2 2 1 Cenp-F N-terminal domain TF_Zn_Ribbon PF08271.12 KXG48355.1 - 0.011 15.2 0.6 0.023 14.2 0.6 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DivIVA PF05103.13 KXG48355.1 - 0.046 13.8 1.6 0.46 10.6 1.6 2.0 1 1 0 1 1 1 0 DivIVA protein CLZ PF16526.5 KXG48355.1 - 0.15 12.4 4.9 3.4 8.1 1.6 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ArfGap PF01412.18 KXG48355.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf CENP-F_leu_zip PF10473.9 KXG48355.1 - 0.21 11.6 4.9 8.8 6.3 1.4 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.15 KXG48355.1 - 0.62 10.2 8.7 4.5 7.4 0.1 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Nodulin-like PF06813.13 KXG48356.1 - 1.9e-23 83.2 1.7 3.8e-23 82.3 1.7 1.5 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 KXG48356.1 - 1.2e-13 50.7 40.1 1.4e-13 50.5 33.1 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Serinc PF03348.15 KXG48357.1 - 1.1e-149 499.0 10.7 1.3e-149 498.8 10.7 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF21 PF01595.20 KXG48357.1 - 0.015 15.0 1.8 0.015 15.0 1.8 3.4 2 1 2 4 4 4 0 Cyclin M transmembrane N-terminal domain MutL_C PF08676.11 KXG48358.1 - 8.1e-24 84.1 0.0 2e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KXG48358.1 - 1.7e-18 66.4 0.0 2.1e-17 62.9 0.0 2.8 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KXG48358.1 - 2.2e-11 43.7 0.1 6.1e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXG48358.1 - 1.7e-06 28.5 0.1 1.1e-05 25.9 0.0 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SDA1 PF05285.12 KXG48358.1 - 0.21 11.0 14.0 0.34 10.3 14.0 1.3 1 0 0 1 1 1 0 SDA1 GCN5L1 PF06320.13 KXG48359.1 - 2.5e-20 72.7 2.3 3.9e-20 72.1 2.3 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Noggin PF05806.12 KXG48359.1 - 0.1 12.5 0.3 0.13 12.1 0.3 1.2 1 0 0 1 1 1 0 Noggin Sugar_tr PF00083.24 KXG48360.1 - 9.7e-100 334.5 18.8 1.1e-99 334.4 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG48360.1 - 5.2e-31 107.8 46.7 3.5e-26 92.0 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG48360.1 - 0.0071 14.8 1.0 0.0071 14.8 1.0 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3712 PF12505.8 KXG48361.1 - 9.5e-27 93.7 0.0 1.8e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) DUF1279 PF06916.13 KXG48361.1 - 0.011 16.3 0.1 0.026 15.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) 7TM_GPCR_Srh PF10318.9 KXG48361.1 - 0.082 11.9 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Mannosyl_trans3 PF11051.8 KXG48362.1 - 3.8e-58 197.0 0.0 2e-57 194.6 0.0 1.9 1 1 0 1 1 1 1 Mannosyltransferase putative TetR_C_37 PF18665.1 KXG48362.1 - 0.1 13.2 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Chitin_synth_2 PF03142.15 KXG48363.1 - 1e-240 799.9 0.8 1.4e-240 799.4 0.8 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KXG48363.1 - 1.6e-72 244.8 0.0 2.1e-71 241.1 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 KXG48363.1 - 9e-16 57.8 0.1 2.6e-12 46.7 0.0 2.9 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 KXG48363.1 - 6.1e-15 54.9 0.1 7.5e-14 51.4 0.4 2.5 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 KXG48363.1 - 8.8e-10 38.8 4.4 2.3e-09 37.4 4.4 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXG48363.1 - 2.7e-09 37.3 0.0 7.4e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RsgA_GTPase PF03193.16 KXG48363.1 - 0.016 15.1 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KXG48363.1 - 0.027 14.8 0.1 0.094 13.1 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain Glycos_transf_2 PF00535.26 KXG48363.1 - 0.067 13.0 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 ABC_tran PF00005.27 KXG48363.1 - 0.11 13.0 0.0 0.33 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Chitin_synth_2 PF03142.15 KXG48364.1 - 7.1e-229 760.8 0.0 9.7e-229 760.3 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 KXG48364.1 - 1.5e-15 56.9 0.8 4.2e-15 55.4 0.8 1.8 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 KXG48364.1 - 8.7e-13 48.6 2.1 8.7e-13 48.6 2.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 KXG48364.1 - 8.7e-12 45.0 0.9 1.7e-06 28.0 0.1 3.1 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 KXG48364.1 - 1.3e-11 44.8 0.0 2.8e-10 40.5 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 KXG48364.1 - 7e-09 34.5 0.0 2.1e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 KXG48364.1 - 0.0011 18.5 0.0 0.0076 15.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXG48364.1 - 0.0087 15.9 0.0 0.26 11.1 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_hydro_2_N PF02837.18 KXG48365.1 - 1.3e-13 51.2 0.0 3.3e-13 49.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KXG48365.1 - 1.4e-11 44.1 0.1 7.5e-10 38.4 0.1 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 KXG48365.1 - 1.8e-07 31.8 0.0 3.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 tify PF06200.14 KXG48365.1 - 0.12 11.8 0.5 0.23 10.8 0.5 1.5 1 0 0 1 1 1 0 tify domain KH_1 PF00013.29 KXG48366.1 - 5.3e-32 109.4 4.3 3.4e-08 33.2 0.0 6.5 6 0 0 6 6 6 5 KH domain HAD_2 PF13419.6 KXG48368.1 - 6.7e-09 36.1 0.0 1.1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXG48368.1 - 1.2e-07 32.3 0.0 2.5e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXG48368.1 - 0.003 17.6 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF4437 PF14499.6 KXG48368.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Dynactin PF12455.8 KXG48369.1 - 4.9e-87 291.8 10.5 4.9e-87 291.8 10.5 4.9 3 1 0 5 5 5 2 Dynein associated protein CAP_GLY PF01302.25 KXG48369.1 - 1.5e-23 82.5 0.2 2.7e-23 81.7 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF2353 PF09789.9 KXG48369.1 - 0.00052 19.5 26.7 0.00052 19.5 26.7 4.1 3 1 1 4 4 4 2 Uncharacterized coiled-coil protein (DUF2353) Solute_trans_a PF03619.16 KXG48371.1 - 5.9e-83 278.4 8.9 7.8e-83 278.0 8.9 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Aminotran_1_2 PF00155.21 KXG48373.1 - 5.1e-19 68.7 0.0 6.6e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KXG48373.1 - 0.00071 18.5 0.0 0.0015 17.4 0.0 1.4 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Wax2_C PF12076.8 KXG48373.1 - 0.057 13.1 0.4 0.1 12.3 0.4 1.3 1 0 0 1 1 1 0 WAX2 C-terminal domain TPP_enzyme_N PF02776.18 KXG48374.1 - 3e-39 134.4 0.0 2.3e-38 131.5 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXG48374.1 - 5.2e-21 75.0 0.1 1.3e-20 73.7 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXG48374.1 - 3.4e-15 56.0 0.2 1.4e-14 54.0 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain DUF2207 PF09972.9 KXG48375.1 - 3 6.5 0.0 3 6.5 0.0 3.0 1 1 2 3 3 3 0 Predicted membrane protein (DUF2207) DUF2235 PF09994.9 KXG48376.1 - 1e-78 264.6 0.0 1.4e-78 264.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Sec20 PF03908.13 KXG48376.1 - 0.13 12.2 1.0 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Sec20 MmgE_PrpD PF03972.14 KXG48377.1 - 5.7e-109 364.6 0.0 7.9e-109 364.1 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family PLDc_2 PF13091.6 KXG48377.1 - 1e-19 70.8 0.0 2.8e-12 46.7 0.1 2.7 3 0 0 3 3 3 2 PLD-like domain Regulator_TrmB PF11495.8 KXG48377.1 - 0.0026 17.0 0.0 0.0075 15.5 0.0 1.7 2 0 0 2 2 2 1 Archaeal transcriptional regulator TrmB PLDc PF00614.22 KXG48377.1 - 0.016 15.3 0.1 2.1 8.7 0.0 2.7 2 0 0 2 2 2 0 Phospholipase D Active site motif BCDHK_Adom3 PF10436.9 KXG48378.1 - 2.6e-46 157.4 0.0 3.5e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXG48378.1 - 4e-13 49.8 0.0 1.2e-12 48.3 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXG48378.1 - 0.22 11.4 0.0 1.9 8.3 0.0 2.1 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.16 KXG48379.1 - 0.0017 19.0 0.1 0.0019 18.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1989 PF09347.10 KXG48380.1 - 6.8e-61 204.7 0.0 8.8e-61 204.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) RIBIOP_C PF04950.12 KXG48381.1 - 1.9e-95 319.6 0.0 1.9e-95 319.6 0.0 1.7 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KXG48381.1 - 1.4e-28 98.8 0.0 4.1e-28 97.3 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 KXG48381.1 - 8.4e-06 26.1 0.2 2.7e-05 24.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KXG48381.1 - 9e-05 22.9 0.0 0.00025 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KXG48381.1 - 0.00028 21.4 0.9 0.0012 19.3 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.6 KXG48381.1 - 0.0003 21.0 1.4 0.00043 20.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain GTP_EFTU PF00009.27 KXG48381.1 - 0.00042 19.9 0.0 0.083 12.4 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXG48381.1 - 0.00044 20.3 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 KXG48381.1 - 0.0015 18.4 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KXG48381.1 - 0.002 18.5 0.0 0.004 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXG48381.1 - 0.0022 18.4 0.0 0.0056 17.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXG48381.1 - 0.0089 16.6 0.7 0.049 14.2 0.1 2.7 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 KXG48381.1 - 0.0092 15.2 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain cobW PF02492.19 KXG48381.1 - 0.013 15.1 0.1 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KXG48381.1 - 0.017 15.4 0.1 0.069 13.4 0.1 2.1 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXG48381.1 - 0.017 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KXG48381.1 - 0.022 14.2 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RNA_helicase PF00910.22 KXG48381.1 - 0.023 15.1 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KXG48381.1 - 0.025 14.3 0.1 0.069 12.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXG48381.1 - 0.03 14.4 0.0 0.086 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KXG48381.1 - 0.035 14.0 1.0 0.056 13.4 0.0 1.8 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea MobB PF03205.14 KXG48381.1 - 0.037 13.9 0.1 0.16 11.9 0.1 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.14 KXG48381.1 - 0.039 13.2 0.0 0.083 12.1 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain NTPase_1 PF03266.15 KXG48381.1 - 0.044 13.7 0.3 0.087 12.7 0.3 1.5 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 KXG48381.1 - 0.046 13.2 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KXG48381.1 - 0.047 13.7 0.1 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Roc PF08477.13 KXG48381.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KXG48381.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 KXG48381.1 - 0.076 12.6 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXG48381.1 - 0.092 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 KXG48381.1 - 0.12 12.1 0.1 0.71 9.6 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 KXG48381.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_21 PF13304.6 KXG48381.1 - 6.2 6.5 10.7 2.3 7.9 0.0 2.9 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MFS_1 PF07690.16 KXG48384.1 - 3.5e-41 141.3 27.9 3.5e-41 141.3 27.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG48384.1 - 1.7e-10 40.0 1.4 1.7e-10 40.0 1.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXG48384.1 - 4.3e-06 25.9 19.7 1.2e-05 24.4 19.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter LapA_dom PF06305.11 KXG48384.1 - 2.1 8.2 9.6 2.2 8.2 0.8 3.9 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain DUF1772 PF08592.11 KXG48384.1 - 2.9 8.2 18.4 0.33 11.3 0.2 4.4 3 2 0 3 3 3 0 Domain of unknown function (DUF1772) Fungal_trans PF04082.18 KXG48385.1 - 8.8e-19 67.6 0.0 1.4e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_24 PF13578.6 KXG48386.1 - 1.1e-12 48.9 0.0 1.7e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF1442 PF07279.11 KXG48386.1 - 1.2e-05 24.7 0.0 1.7e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1442) Methyltransf_3 PF01596.17 KXG48386.1 - 1.5e-05 24.3 0.0 3.1e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.6 KXG48386.1 - 0.07 12.9 0.1 3.7 7.3 0.1 2.0 1 1 1 2 2 2 0 Methyltransferase domain Glyoxalase PF00903.25 KXG48387.1 - 1.5e-11 44.6 0.1 8e-11 42.2 0.1 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXG48387.1 - 3.6e-05 24.0 0.0 0.00042 20.6 0.0 2.3 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KXG48387.1 - 0.17 12.7 0.0 1 10.2 0.0 2.2 2 1 0 2 2 2 0 Glyoxalase-like domain PWI PF01480.17 KXG48388.1 - 1.2e-11 44.8 0.2 3.3e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 PWI domain Nup35_RRM_2 PF14605.6 KXG48388.1 - 1.5e-06 28.1 0.0 0.0014 18.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 KXG48388.1 - 4.2e-06 26.5 0.4 0.0003 20.5 0.1 2.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXG48388.1 - 0.0069 16.2 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 Occluded RNA-recognition motif DUF4407 PF14362.6 KXG48388.1 - 8.2 5.7 11.8 13 5.1 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GTP_EFTU PF00009.27 KXG48389.1 - 3.3e-65 219.3 0.0 4.8e-65 218.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KXG48389.1 - 5.9e-34 116.5 0.0 1.7e-33 114.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KXG48389.1 - 2.3e-22 78.8 0.0 8e-22 77.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KXG48389.1 - 1.9e-12 47.1 0.0 6e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KXG48389.1 - 1.8e-11 44.2 0.5 6.4e-11 42.5 0.2 2.2 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXG48389.1 - 0.0001 22.3 0.0 0.00025 21.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Asp PF00026.23 KXG48390.1 - 1.9e-43 149.1 2.2 3.2e-43 148.3 2.2 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KXG48390.1 - 1e-05 25.4 0.1 0.00011 22.0 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal RhoGAP-FF1 PF16512.5 KXG48391.1 - 0.57 10.9 1.7 0.76 10.5 0.5 1.8 2 0 0 2 2 2 0 p190-A and -B Rho GAPs FF domain Pkinase PF00069.25 KXG48392.1 - 2.9e-57 194.1 0.0 3.8e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48392.1 - 1.3e-43 149.2 0.0 1.9e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG48392.1 - 0.0002 20.7 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXG48392.1 - 0.0025 16.6 0.3 0.012 14.4 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KXG48392.1 - 0.004 16.5 0.1 0.009 15.4 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXG48392.1 - 0.0041 17.1 0.0 0.018 14.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXG48392.1 - 0.013 15.1 0.1 0.043 13.4 0.1 1.8 1 1 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KXG48392.1 - 0.031 13.9 0.0 0.087 12.4 0.0 1.8 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 KXG48394.1 - 4.3e-67 226.3 0.0 5.8e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48394.1 - 9.9e-33 113.5 0.0 1.6e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG48394.1 - 1.7e-05 24.3 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXG48394.1 - 0.00041 19.2 0.0 0.0008 18.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXG48394.1 - 0.0015 17.9 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KXG48394.1 - 0.013 15.0 0.1 0.045 13.3 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL SRR1 PF07985.12 KXG48395.1 - 1.6e-06 28.1 0.0 3.6e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 SRR1 Aminotran_1_2 PF00155.21 KXG48396.1 - 7.5e-23 81.3 0.0 8.6e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KXG48396.1 - 0.022 13.6 0.0 0.046 12.5 0.0 1.5 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase DUF3455 PF11937.8 KXG48397.1 - 4.8e-43 147.3 0.1 5.9e-43 147.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) SF3b1 PF08920.10 KXG48398.1 - 1.1e-22 80.8 1.1 4.1e-22 78.9 1.1 2.1 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 KXG48398.1 - 5.5e-14 52.3 7.4 0.54 10.7 0.0 8.0 6 1 3 9 9 9 5 HEAT repeats HEAT_EZ PF13513.6 KXG48398.1 - 2.2e-12 47.2 1.1 0.0072 16.8 0.0 7.1 7 0 0 7 7 7 2 HEAT-like repeat HEAT PF02985.22 KXG48398.1 - 4.7e-09 35.7 11.0 0.31 11.4 0.2 8.6 9 0 0 9 9 8 2 HEAT repeat Cnd1 PF12717.7 KXG48398.1 - 6.1e-08 32.9 2.0 0.66 10.0 0.0 6.5 5 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXG48398.1 - 2.3e-05 24.9 0.2 4.2 8.0 0.0 4.9 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KXG48398.1 - 0.00015 21.7 0.7 0.45 10.4 0.1 5.0 4 2 0 4 4 4 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 KXG48398.1 - 0.00019 20.2 0.0 0.4 9.2 0.0 3.4 2 2 2 4 4 4 2 Adaptin N terminal region NUC173 PF08161.12 KXG48398.1 - 0.0057 16.3 0.1 0.93 9.1 0.0 4.2 4 1 1 5 5 5 1 NUC173 domain MMS19_C PF12460.8 KXG48398.1 - 0.04 13.0 0.0 4.6 6.3 0.0 3.6 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KXG48398.1 - 0.085 12.4 0.2 1.3 8.5 0.0 2.8 3 0 0 3 3 3 0 CLASP N terminal zf-H2C2_2 PF13465.6 KXG48399.1 - 3.3e-10 39.9 14.6 3.6e-05 24.0 0.4 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KXG48399.1 - 1e-09 38.3 11.6 2.1e-05 24.7 4.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXG48399.1 - 1.1e-06 29.0 10.9 0.0012 19.4 3.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KXG48399.1 - 6e-06 26.5 1.3 1.7e-05 25.0 1.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KXG48399.1 - 5.5e-05 23.0 9.0 0.00011 22.0 2.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXG48399.1 - 0.00073 19.8 1.8 0.00073 19.8 1.8 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXG48399.1 - 0.069 13.5 1.1 0.069 13.5 1.1 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KXG48399.1 - 0.09 12.7 4.2 2.8 7.9 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Actin_micro PF17003.5 KXG48399.1 - 0.22 10.7 0.2 0.29 10.2 0.2 1.1 1 0 0 1 1 1 0 Putative actin-like family zf-C2H2_11 PF16622.5 KXG48399.1 - 0.24 11.2 6.4 4.8 7.0 0.5 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type FAD_binding_2 PF00890.24 KXG48400.1 - 1.2e-42 146.5 0.5 7.1e-42 143.9 0.5 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXG48400.1 - 3.1e-10 40.2 1.8 3.1e-10 40.2 1.8 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG48400.1 - 3.9e-07 29.6 0.8 3.3e-05 23.3 0.2 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG48400.1 - 0.00014 21.2 0.4 0.00037 19.8 0.0 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KXG48400.1 - 0.00015 20.6 1.7 0.026 13.2 0.0 3.1 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.12 KXG48400.1 - 0.00045 19.4 0.2 0.00096 18.3 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein GMC_oxred_N PF00732.19 KXG48400.1 - 0.0046 16.4 0.1 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_9 PF13454.6 KXG48400.1 - 0.0071 16.4 0.4 0.43 10.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KXG48400.1 - 0.018 14.4 1.5 0.23 10.8 1.5 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase Anophelin PF10731.9 KXG48400.1 - 0.024 14.5 0.0 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito NAD_binding_8 PF13450.6 KXG48400.1 - 0.026 14.7 0.1 0.067 13.4 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXG48400.1 - 0.039 13.2 0.0 1.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG48400.1 - 0.082 13.5 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXG48400.1 - 1.8 7.5 4.5 1.5 7.8 0.1 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Spem1 PF15670.5 KXG48401.1 - 0.0079 15.8 1.8 0.016 14.8 1.8 1.4 1 0 0 1 1 1 1 Spermatid maturation protein 1 Sec1 PF00995.23 KXG48402.1 - 4.4e-115 386.1 0.0 5e-115 385.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Transposase_22 PF02994.14 KXG48402.1 - 0.064 13.4 0.4 0.24 11.6 0.0 2.2 3 0 0 3 3 3 0 L1 transposable element RBD-like domain Telomere_reg-2 PF10193.9 KXG48403.1 - 5.3e-28 97.6 0.0 2.4e-27 95.5 0.0 2.2 2 0 0 2 2 2 1 Telomere length regulation protein AphA_like PF14557.6 KXG48403.1 - 0.0051 16.5 0.2 0.18 11.5 0.0 2.8 3 0 0 3 3 3 1 Putative AphA-like transcriptional regulator ThiF PF00899.21 KXG48404.1 - 3e-66 223.3 0.0 4.4e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KXG48404.1 - 5.5e-29 100.1 0.1 9.8e-29 99.3 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KXG48404.1 - 0.00019 21.5 0.3 0.0016 18.5 0.0 2.2 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KXG48404.1 - 0.044 14.1 0.3 0.49 10.7 0.1 2.6 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain E1_UFD PF09358.10 KXG48404.1 - 0.045 14.5 0.0 0.12 13.1 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin fold domain UDPG_MGDP_dh_N PF03721.14 KXG48404.1 - 0.05 13.2 0.7 0.18 11.3 0.1 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Cu-oxidase_2 PF07731.14 KXG48404.1 - 0.058 13.1 0.1 0.098 12.4 0.1 1.3 1 0 0 1 1 1 0 Multicopper oxidase UBA_e1_thiolCys PF10585.9 KXG48404.1 - 0.066 13.1 4.3 0.56 10.1 0.1 2.3 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site Pyr_redox PF00070.27 KXG48404.1 - 0.072 13.7 0.1 0.21 12.2 0.0 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Ecm33 PF12454.8 KXG48404.1 - 0.075 13.2 0.3 0.16 12.1 0.3 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein PglD_N PF17836.1 KXG48404.1 - 0.14 12.8 1.3 0.34 11.6 0.7 2.0 1 1 1 2 2 2 0 PglD N-terminal domain RNA_pol_A_bac PF01000.26 KXG48405.1 - 3.7e-28 98.2 0.0 7.9e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KXG48405.1 - 1e-19 69.7 0.0 1.4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.19 KXG48406.1 - 2.1e-123 410.7 0.0 2.9e-123 410.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KXG48406.1 - 0.0093 14.9 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase F-box-like PF12937.7 KXG48407.1 - 0.009 15.9 0.0 0.026 14.4 0.0 1.8 1 1 0 1 1 1 1 F-box-like SAP PF02037.27 KXG48408.1 - 3.8e-11 42.5 0.6 1.3e-10 40.8 0.1 2.1 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 KXG48408.1 - 3.6e-08 33.1 0.3 3.6e-08 33.1 0.3 1.9 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain Creatinase_N PF01321.18 KXG48408.1 - 0.025 15.2 0.9 5.3 7.7 0.1 2.3 2 0 0 2 2 2 0 Creatinase/Prolidase N-terminal domain CW_binding_2 PF04122.12 KXG48408.1 - 0.034 14.8 0.4 0.07 13.8 0.4 1.5 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 PT PF04886.12 KXG48408.1 - 1 9.0 10.2 0.42 10.2 0.7 2.5 2 0 0 2 2 2 0 PT repeat FANC_SAP PF18081.1 KXG48408.1 - 1.7 8.8 4.5 1.1 9.5 0.4 2.4 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain Usp PF00582.26 KXG48408.1 - 3 8.3 7.1 0.56 10.7 0.7 2.3 2 0 0 2 2 2 0 Universal stress protein family Methyltransf_11 PF08241.12 KXG48409.1 - 0.0042 17.7 0.0 0.011 16.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ATP-synt_DE PF00401.20 KXG48409.1 - 0.056 13.7 3.6 0.23 11.8 3.9 1.9 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Annexin PF00191.20 KXG48410.1 - 4.3e-56 186.9 0.6 1.8e-16 59.9 0.0 4.3 4 0 0 4 4 4 4 Annexin RPA_interact_N PF14766.6 KXG48410.1 - 0.094 12.4 0.4 0.22 11.2 0.4 1.6 1 0 0 1 1 1 0 Replication protein A interacting N-terminal DBP10CT PF08147.12 KXG48410.1 - 0.31 11.3 1.7 0.61 10.4 1.7 1.4 1 0 0 1 1 1 0 DBP10CT (NUC160) domain zf-C3HC4 PF00097.25 KXG48411.1 - 1.5e-07 31.2 2.1 1.5e-07 31.2 2.1 4.3 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXG48411.1 - 7.8e-07 29.0 2.1 7.8e-07 29.0 2.1 3.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXG48411.1 - 2.5e-05 24.5 4.0 2.5e-05 24.5 4.0 4.3 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.6 KXG48411.1 - 5.4e-05 23.0 5.0 5.4e-05 23.0 5.0 3.6 3 3 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXG48411.1 - 5.5e-05 23.2 3.1 5.5e-05 23.2 3.1 3.8 5 1 0 5 5 5 1 zinc finger of C3HC4-type, RING SH3_9 PF14604.6 KXG48411.1 - 0.00018 21.3 0.1 0.00018 21.3 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain zf-RING_5 PF14634.6 KXG48411.1 - 0.00025 21.0 2.5 0.00025 21.0 2.5 5.4 5 0 0 5 5 5 1 zinc-RING finger domain SH3_1 PF00018.28 KXG48411.1 - 0.0033 17.0 0.1 0.0081 15.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain zf-RING_6 PF14835.6 KXG48411.1 - 0.0063 16.4 0.1 0.0063 16.4 0.1 2.9 3 0 0 3 3 3 1 zf-RING of BARD1-type protein SH3_2 PF07653.17 KXG48411.1 - 0.01 15.5 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain CBM_21 PF03370.13 KXG48412.1 - 8.4e-37 125.8 0.6 1.3e-36 125.2 0.6 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KXG48412.1 - 2.2e-10 41.0 2.4 4.7e-10 39.9 2.4 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Aft1_HRR PF11787.8 KXG48412.1 - 0.36 12.0 10.7 0.25 12.5 0.8 4.1 3 0 0 3 3 3 0 Aft1 HRR domain CENP-T_C PF15511.6 KXG48413.1 - 4.4e-09 36.4 0.1 5.3e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KXG48413.1 - 1.9e-05 25.1 0.2 2.2e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KXG48413.1 - 5e-05 23.4 0.2 7.3e-05 22.9 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXG48413.1 - 0.00012 22.3 0.1 0.00021 21.5 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KXG48413.1 - 0.00017 21.9 0.1 0.00023 21.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KXG48413.1 - 0.0038 17.3 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXG48413.1 - 0.0045 17.0 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 KXG48413.1 - 0.05 13.4 0.2 0.061 13.1 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TFIID_20kDa PF03847.13 KXG48413.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 KXG48413.1 - 0.073 13.1 0.0 0.082 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region PAD_porph PF04371.15 KXG48414.1 - 1.4e-90 303.9 0.0 1.6e-90 303.6 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Fungal_trans_2 PF11951.8 KXG48415.1 - 9.5e-05 21.4 0.3 0.00016 20.6 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain PLAC9 PF15205.6 KXG48415.1 - 0.04 14.3 0.0 0.22 11.9 0.0 2.1 2 0 0 2 2 2 0 Placenta-specific protein 9 Acetyltransf_3 PF13302.7 KXG48416.1 - 4.7e-11 43.5 0.0 6.5e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG48416.1 - 6.9e-10 39.2 0.0 1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXG48416.1 - 0.00021 21.7 0.1 0.00033 21.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXG48416.1 - 0.00087 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mito_carr PF00153.27 KXG48417.1 - 4.8e-47 157.8 1.6 2.3e-16 59.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF883 PF05957.13 KXG48417.1 - 0.13 12.9 3.5 1.3 9.7 2.6 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF346 PF03984.13 KXG48417.1 - 0.28 11.0 1.7 0.65 9.8 1.7 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) Phasin_2 PF09361.10 KXG48417.1 - 1.2 9.5 5.1 5.6 7.3 1.0 2.9 2 1 0 2 2 2 0 Phasin protein F-box-like PF12937.7 KXG48418.1 - 0.00072 19.4 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like Acetyltransf_3 PF13302.7 KXG48419.1 - 9.3e-19 68.5 0.0 1.2e-18 68.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG48419.1 - 1.6e-05 25.1 0.0 2.3e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KXG48419.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Nsp2a_N PF17896.1 KXG48419.1 - 0.17 11.0 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Replicase polyprotein 1a N-terminal domain Cornifin PF02389.15 KXG48420.1 - 0.00032 20.9 0.1 0.0011 19.2 0.1 1.7 1 1 0 1 1 1 1 Cornifin (SPRR) family PBCV_basic_adap PF08789.10 KXG48420.1 - 0.055 13.6 0.7 5.1e+02 0.9 0.0 5.1 6 0 0 6 6 6 0 PBCV-specific basic adaptor domain 2OG-FeII_Oxy_3 PF13640.6 KXG48421.1 - 5.7e-09 36.8 0.1 4.4e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily EBP PF05241.12 KXG48422.1 - 2.3e-66 222.7 6.5 2.7e-66 222.4 6.5 1.0 1 0 0 1 1 1 1 Emopamil binding protein SesA PF17107.5 KXG48423.1 - 7.3e-05 23.0 0.0 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3292 PF11696.8 KXG48424.1 - 1.8e-227 756.8 0.0 2.3e-227 756.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) DUF2182 PF09948.9 KXG48424.1 - 0.021 14.7 0.4 0.038 13.9 0.4 1.3 1 0 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) Pex24p PF06398.11 KXG48424.1 - 0.022 13.8 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Ank_2 PF12796.7 KXG48425.1 - 4.6e-61 203.4 18.8 1.6e-14 54.3 0.2 12.8 6 2 6 13 13 13 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG48425.1 - 2e-52 174.9 25.7 4.4e-07 30.3 0.0 19.4 15 5 7 22 22 22 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG48425.1 - 9.3e-49 162.9 25.3 8.3e-10 38.7 0.1 16.6 13 5 5 18 18 18 12 Ankyrin repeats (many copies) Ank PF00023.30 KXG48425.1 - 8.1e-43 143.1 36.2 4.3e-07 30.1 0.0 19.1 19 1 0 19 19 19 11 Ankyrin repeat Ank_3 PF13606.6 KXG48425.1 - 2.7e-33 110.3 27.9 5.3e-08 32.5 0.0 19.7 24 0 0 24 24 24 6 Ankyrin repeat L31 PF09784.9 KXG48428.1 - 5.5e-46 155.2 1.5 6.2e-46 155.0 1.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Acyltransferase PF01553.21 KXG48429.1 - 2.7e-08 33.5 0.0 3.8e-07 29.8 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase Amidase PF01425.21 KXG48431.1 - 3.8e-65 220.6 0.0 1.2e-61 209.1 0.0 2.1 1 1 1 2 2 2 2 Amidase Glyco_transf_52 PF07922.11 KXG48432.1 - 0.19 11.0 0.6 0.35 10.1 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase family 52 TPR_12 PF13424.6 KXG48434.1 - 7.1e-24 83.9 8.0 4.3e-08 33.3 0.0 5.7 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXG48434.1 - 2.9e-13 49.0 5.4 0.0083 15.9 0.0 5.3 6 0 0 6 6 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXG48434.1 - 7e-13 47.6 4.3 0.0042 17.1 0.0 6.1 6 0 0 6 6 5 4 Tetratricopeptide repeat NB-ARC PF00931.22 KXG48434.1 - 6.2e-12 45.2 0.6 1.4e-11 44.1 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain TPR_10 PF13374.6 KXG48434.1 - 1.1e-09 37.9 6.1 0.15 11.9 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat AAA_16 PF13191.6 KXG48434.1 - 2.9e-07 31.0 0.1 1.6e-06 28.6 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain TPR_7 PF13176.6 KXG48434.1 - 1.4e-06 27.9 2.3 9.5 6.5 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXG48434.1 - 4.4e-06 26.3 0.0 0.25 11.0 0.0 4.1 3 0 0 3 3 3 1 TPR repeat TPR_MalT PF17874.1 KXG48434.1 - 5.2e-05 22.8 1.7 0.011 15.1 0.2 3.4 3 1 0 3 3 3 1 MalT-like TPR region SNAP PF14938.6 KXG48434.1 - 9.2e-05 22.0 0.0 0.041 13.3 0.0 2.6 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 KXG48434.1 - 0.00028 21.4 1.1 4.5 8.3 0.0 5.2 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXG48434.1 - 0.00057 19.9 5.1 7 7.1 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXG48434.1 - 0.0058 17.1 0.0 3.3 8.6 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXG48434.1 - 0.0071 16.8 0.0 0.24 11.9 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.6 KXG48434.1 - 0.0071 16.6 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_16 PF13432.6 KXG48434.1 - 0.0079 16.8 4.7 0.87 10.3 0.1 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TFIIA_gamma_N PF02268.16 KXG48434.1 - 0.027 14.5 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain AAA_24 PF13479.6 KXG48434.1 - 0.043 13.5 0.1 0.6 9.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain Prefoldin PF02996.17 KXG48434.1 - 0.088 12.7 3.1 5.6 6.9 0.1 3.0 2 0 0 2 2 2 0 Prefoldin subunit DUF1722 PF08349.11 KXG48434.1 - 0.09 13.1 0.3 0.43 10.9 0.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) DUF3856 PF12968.7 KXG48434.1 - 0.11 12.5 2.1 20 5.3 0.0 3.8 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 KXG48434.1 - 0.25 12.1 8.7 27 5.7 0.1 5.6 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 KXG48434.1 - 9.4 6.3 7.3 67 3.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.29 KXG48435.1 - 4.9e-42 143.7 0.8 7.8e-42 143.0 0.8 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG48435.1 - 2.7e-32 111.4 1.2 7.2e-30 103.6 0.1 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KXG48435.1 - 2.5e-08 34.1 1.3 2.6e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CCDC106 PF15794.5 KXG48435.1 - 5 6.8 10.6 0.14 11.9 3.7 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 TBCC_N PF16752.5 KXG48437.1 - 6.3 7.3 8.5 12 6.4 1.8 2.6 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Guanylate_kin PF00625.21 KXG48438.1 - 5.1e-52 176.2 0.0 6.3e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 KXG48438.1 - 0.0011 19.2 0.1 0.068 13.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXG48438.1 - 0.0013 19.1 0.1 0.0038 17.6 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KXG48438.1 - 0.0016 17.7 0.1 0.14 11.4 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 KXG48438.1 - 0.0022 18.1 0.1 0.012 15.7 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KXG48438.1 - 0.003 17.8 0.0 0.005 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KXG48438.1 - 0.0049 16.8 0.0 0.0089 15.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 KXG48438.1 - 0.016 15.7 0.2 0.082 13.5 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXG48438.1 - 0.031 14.0 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 KXG48438.1 - 0.034 13.7 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 KXG48438.1 - 0.04 13.6 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 KXG48438.1 - 0.042 14.4 0.1 0.049 14.1 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KXG48438.1 - 0.042 13.3 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Rad17 PF03215.15 KXG48438.1 - 0.043 13.7 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 KXG48438.1 - 0.045 13.7 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 KXG48438.1 - 0.075 12.9 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 KXG48438.1 - 0.082 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 KXG48438.1 - 0.098 12.9 0.5 0.39 10.9 0.1 2.1 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KXG48438.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain FixS PF03597.15 KXG48439.1 - 0.19 11.5 2.6 0.38 10.5 2.6 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type tRNA-synt_1d PF00750.19 KXG48441.1 - 6.4e-99 331.2 7.5 1.4e-97 326.8 7.5 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (R) ABC_tran PF00005.27 KXG48441.1 - 3.3e-27 95.7 1.0 6.8e-27 94.7 0.1 2.1 2 0 0 2 2 1 1 ABC transporter DALR_1 PF05746.15 KXG48441.1 - 4.7e-26 91.3 0.2 4.7e-26 91.3 0.2 1.9 2 0 0 2 2 1 1 DALR anticodon binding domain ABC2_membrane PF01061.24 KXG48441.1 - 5.5e-26 91.3 30.6 8.2e-26 90.7 30.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter Arg_tRNA_synt_N PF03485.16 KXG48441.1 - 1.3e-08 35.3 0.2 9.9e-08 32.5 0.0 2.5 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain AAA_16 PF13191.6 KXG48441.1 - 2.7e-07 31.1 0.2 7.1e-07 29.8 0.2 1.7 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXG48441.1 - 3.6e-06 27.0 0.0 0.0002 21.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KXG48441.1 - 3.5e-05 23.5 0.2 8.9e-05 22.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.15 KXG48441.1 - 0.00064 19.7 0.0 0.0028 17.6 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 KXG48441.1 - 0.00067 19.8 0.0 0.0018 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXG48441.1 - 0.0013 19.0 0.0 0.0032 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KXG48441.1 - 0.0015 18.4 0.2 1.1 9.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TsaE PF02367.17 KXG48441.1 - 0.0038 17.2 0.0 0.023 14.7 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KXG48441.1 - 0.007 16.9 0.0 0.024 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXG48441.1 - 0.0073 16.7 0.1 0.029 14.8 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KXG48441.1 - 0.0093 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 KXG48441.1 - 0.01 15.5 0.0 0.03 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXG48441.1 - 0.011 16.0 0.0 0.04 14.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXG48441.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 KXG48441.1 - 0.016 15.2 0.0 0.16 12.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KXG48441.1 - 0.019 15.1 0.1 0.095 12.8 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 KXG48441.1 - 0.02 15.4 2.2 0.91 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXG48441.1 - 0.023 15.1 0.0 0.071 13.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Phage_GP20 PF06810.11 KXG48441.1 - 0.027 14.3 1.5 0.059 13.2 1.5 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 ATPase_2 PF01637.18 KXG48441.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_13 PF13166.6 KXG48441.1 - 0.048 12.3 4.7 0.1 11.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KXG48441.1 - 0.05 12.8 1.4 1.1 8.4 0.0 3.3 3 1 1 4 4 4 0 NB-ARC domain cobW PF02492.19 KXG48441.1 - 0.069 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KXG48441.1 - 0.07 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 NTPase CbiA PF01656.23 KXG48441.1 - 0.096 12.7 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Golgin_A5 PF09787.9 KXG48441.1 - 0.21 11.0 3.9 0.52 9.7 0.3 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 FAD_binding_6 PF00970.24 KXG48442.1 - 2.4e-33 114.4 0.0 3.8e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXG48442.1 - 3.7e-27 95.1 0.0 5.8e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KXG48442.1 - 1.1e-06 28.9 0.0 0.00046 20.3 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KXG48442.1 - 0.021 15.0 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF3605 PF12239.8 KXG48443.1 - 1e-59 201.3 0.0 1.2e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Methyltransf_2 PF00891.18 KXG48446.1 - 1.1e-22 80.4 0.0 1.8e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KXG48446.1 - 0.0091 16.0 0.0 0.03 14.3 0.0 1.8 2 0 0 2 2 2 1 Dimerisation domain Rrf2 PF02082.20 KXG48446.1 - 0.15 12.4 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator SMC_N PF02463.19 KXG48447.1 - 2.9e-73 245.9 0.3 5.2e-73 245.1 0.3 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXG48447.1 - 8.1e-32 110.0 0.0 5.2e-31 107.4 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KXG48447.1 - 6.2e-19 69.3 3.1 6.2e-19 69.3 3.1 7.0 2 2 3 5 5 3 1 AAA domain AAA_21 PF13304.6 KXG48447.1 - 1.2e-16 61.5 10.5 9.7e-11 42.0 0.0 3.5 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KXG48447.1 - 3.9e-15 56.4 40.8 4.5e-10 39.8 10.6 4.3 2 2 1 3 3 3 2 AAA ATPase domain APG6_N PF17675.1 KXG48447.1 - 0.0023 18.4 11.4 0.0023 18.4 11.4 8.4 2 2 4 8 8 8 2 Apg6 coiled-coil region FtsK_SpoIIIE PF01580.18 KXG48447.1 - 0.003 17.0 1.6 0.14 11.5 0.0 3.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF4201 PF13870.6 KXG48447.1 - 0.0041 16.9 10.3 0.0041 16.9 10.3 7.2 4 1 2 7 7 7 1 Domain of unknown function (DUF4201) AAA_29 PF13555.6 KXG48447.1 - 0.0054 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain XH PF03469.14 KXG48447.1 - 0.0069 16.3 6.1 0.019 14.8 0.6 3.7 2 0 0 2 2 2 1 XH domain FliD_N PF02465.18 KXG48447.1 - 0.011 16.3 3.0 0.011 16.3 3.0 7.8 5 3 2 8 8 7 0 Flagellar hook-associated protein 2 N-terminus TMF_TATA_bd PF12325.8 KXG48447.1 - 0.013 15.7 4.7 0.013 15.7 4.7 9.0 6 3 3 9 9 9 0 TATA element modulatory factor 1 TATA binding DUF1192 PF06698.11 KXG48447.1 - 0.1 12.7 0.1 0.1 12.7 0.1 6.9 8 0 0 8 8 7 0 Protein of unknown function (DUF1192) DUF211 PF02680.14 KXG48447.1 - 0.18 12.0 2.1 4.1 7.6 0.2 3.1 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 DUF87 PF01935.17 KXG48447.1 - 2.9 7.9 0.0 2.9 7.9 0.0 6.3 3 2 2 5 5 3 0 Helicase HerA, central domain RIO1 PF01163.22 KXG48448.1 - 5.5e-72 241.3 0.1 5.5e-72 241.3 0.1 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KXG48448.1 - 0.005 16.8 0.0 0.81 9.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family APG17 PF04108.12 KXG48449.1 - 1.2e-129 432.9 0.3 1.4e-129 432.7 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 HD_2 PF12917.7 KXG48449.1 - 0.0055 16.5 0.0 0.49 10.1 0.0 2.4 2 0 0 2 2 2 1 HD containing hydrolase-like enzyme HR1 PF02185.16 KXG48449.1 - 0.02 15.0 1.8 0.25 11.5 0.2 2.6 2 0 0 2 2 2 0 Hr1 repeat Apt1 PF10351.9 KXG48449.1 - 0.41 9.4 3.7 0.22 10.3 0.1 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain Sec34 PF04136.15 KXG48449.1 - 0.66 9.8 3.2 10 6.0 0.0 3.2 3 0 0 3 3 3 0 Sec34-like family Fib_alpha PF08702.10 KXG48449.1 - 0.98 9.6 2.7 9.2 6.4 0.1 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family WD40 PF00400.32 KXG48450.1 - 3.7e-43 144.6 11.0 1e-06 29.3 0.0 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 KXG48450.1 - 4.3e-14 52.1 0.8 9.5e-14 51.0 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXG48450.1 - 1.4e-10 40.8 0.1 3.3e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KXG48450.1 - 1.3e-09 37.2 7.5 0.061 12.0 0.1 5.2 2 2 2 5 5 5 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXG48450.1 - 7.4e-05 23.0 0.3 0.59 10.5 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KXG48450.1 - 0.00045 20.1 0.3 0.0047 16.8 0.0 2.8 3 0 0 3 3 3 1 F-box UCH PF00443.29 KXG48451.1 - 3.5e-60 203.7 0.0 5.3e-60 203.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXG48451.1 - 5.8e-12 45.8 0.0 0.00019 21.2 0.0 3.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KXG48451.1 - 8e-08 32.8 0.0 4e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 DUSP domain PX PF00787.24 KXG48453.1 - 2.4e-17 63.0 0.0 1.3e-16 60.5 0.0 2.3 3 0 0 3 3 3 1 PX domain Vps5 PF09325.10 KXG48453.1 - 2.4e-06 27.3 9.7 0.003 17.1 2.2 2.2 2 0 0 2 2 2 2 Vps5 C terminal like Peptidase_C10 PF01640.17 KXG48453.1 - 0.035 14.4 0.0 0.068 13.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase C10 family Macoilin PF09726.9 KXG48453.1 - 5.9 5.3 7.0 12 4.4 6.7 1.5 1 1 1 2 2 2 0 Macoilin family Glyco_hydro_43 PF04616.14 KXG48454.1 - 2.1e-41 142.2 0.9 2.8e-41 141.7 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF2428 PF10350.9 KXG48456.1 - 5.3e-63 212.8 0.0 5.3e-63 212.8 0.0 2.5 3 0 0 3 3 3 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KXG48456.1 - 5.9e-05 23.0 5.3 11 6.6 0.0 6.8 7 0 0 7 7 7 2 HEAT repeat TraL PF07178.11 KXG48456.1 - 0.19 12.2 1.1 0.28 11.7 0.0 1.7 2 0 0 2 2 2 0 TraL protein Tim17 PF02466.19 KXG48457.1 - 1.9e-27 95.9 4.0 2.5e-27 95.4 4.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Fungal_trans_2 PF11951.8 KXG48458.1 - 4.1e-36 124.6 3.9 5.5e-36 124.2 3.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG48458.1 - 3.2e-11 43.2 8.7 6.5e-11 42.2 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclase PF04199.13 KXG48459.1 - 3.7e-13 49.9 0.0 4.9e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Pkinase PF00069.25 KXG48460.1 - 8.8e-45 153.1 0.0 2.8e-43 148.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48460.1 - 7.1e-26 91.0 0.0 1.1e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXG48460.1 - 0.00052 18.9 0.0 0.00081 18.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXG48460.1 - 0.00055 19.4 0.0 0.0014 18.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXG48460.1 - 0.2 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lipase_3 PF01764.25 KXG48461.1 - 5.9e-20 71.6 0.0 9.5e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KXG48461.1 - 0.0014 19.3 2.3 0.0017 19.0 1.9 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FAD_binding_4 PF01565.23 KXG48462.1 - 1.7e-25 89.4 0.7 2.7e-25 88.8 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG48462.1 - 4e-14 52.4 0.1 1.1e-13 51.0 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like RAI16-like PF10257.9 KXG48464.1 - 8.9e-86 288.0 0.0 1.3e-85 287.5 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein MFS_1 PF07690.16 KXG48464.1 - 2.7e-15 56.2 16.0 2.7e-15 56.2 16.0 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 KXG48464.1 - 0.029 12.6 0.0 0.068 11.5 0.0 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CBFD_NFYB_HMF PF00808.23 KXG48465.1 - 3.2e-16 59.3 2.1 5.2e-16 58.7 2.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXG48465.1 - 1.5e-05 25.4 0.8 1.5e-05 25.4 0.8 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KXG48465.1 - 0.17 12.2 0.5 0.3 11.4 0.5 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X zf-C3HC4_3 PF13920.6 KXG48466.1 - 0.00051 19.8 12.1 0.0009 19.1 12.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 KXG48466.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 U-box domain Oxidored_q6 PF01058.22 KXG48467.1 - 1.7e-22 79.6 0.1 2.4e-22 79.2 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Fungal_trans PF04082.18 KXG48468.1 - 1.9e-24 86.1 1.4 2.6e-24 85.7 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG48468.1 - 0.00029 20.9 10.8 0.00052 20.1 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Corona_M PF01635.18 KXG48468.1 - 0.077 12.3 0.2 0.14 11.4 0.2 1.4 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein DUF1899 PF08953.11 KXG48469.1 - 2.3e-33 113.9 0.0 4.9e-33 112.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KXG48469.1 - 4.6e-21 74.4 0.1 9.8e-21 73.4 0.1 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KXG48469.1 - 2.9e-17 62.7 4.8 0.00034 21.4 0.2 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG48469.1 - 2.3e-06 27.8 0.0 0.03 14.6 0.0 3.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXG48469.1 - 0.00068 18.4 0.2 0.3 9.7 0.3 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 SlyX PF04102.12 KXG48469.1 - 0.14 12.8 2.8 0.24 12.0 1.8 1.8 2 0 0 2 2 2 0 SlyX DivIC PF04977.15 KXG48469.1 - 0.45 10.3 1.5 0.94 9.3 1.5 1.4 1 0 0 1 1 1 0 Septum formation initiator SPX PF03105.19 KXG48469.1 - 3.7 7.4 5.6 5.1 6.9 5.6 1.1 1 0 0 1 1 1 0 SPX domain Kinesin PF00225.23 KXG48470.1 - 4.6e-105 351.2 0.7 4.6e-105 351.2 0.7 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXG48470.1 - 5e-60 201.8 0.0 1.5e-59 200.2 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 KXG48470.1 - 0.012 16.1 0.0 0.012 16.1 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain Bac_DnaA PF00308.18 KXG48470.1 - 0.027 14.3 0.0 0.027 14.3 0.0 2.0 3 0 0 3 3 3 0 Bacterial dnaA protein ATPase_2 PF01637.18 KXG48470.1 - 0.028 14.3 4.4 0.98 9.3 0.0 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KXG48470.1 - 0.46 10.8 0.0 0.46 10.8 0.0 2.9 2 1 1 3 3 3 0 AAA domain WEMBL PF05701.11 KXG48470.1 - 0.78 8.4 38.9 0.046 12.4 11.6 2.4 2 1 1 3 3 3 0 Weak chloroplast movement under blue light CCDC23 PF15674.5 KXG48470.1 - 2.5 8.1 6.0 2.3 8.3 1.7 2.9 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 23 Filament PF00038.21 KXG48470.1 - 3.5 7.1 40.0 1.9 8.0 29.6 3.5 2 1 1 3 3 3 0 Intermediate filament protein Abhydrolase_1 PF00561.20 KXG48471.1 - 4.7e-18 65.7 0.0 7.9e-14 51.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold NUDIX PF00293.28 KXG48471.1 - 1.4e-13 51.0 0.3 2.8e-13 50.1 0.3 1.4 1 0 0 1 1 1 1 NUDIX domain Abhydrolase_6 PF12697.7 KXG48471.1 - 8.5e-09 36.3 0.1 2.4e-08 34.9 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG48471.1 - 2.1e-08 33.7 0.0 4e-07 29.5 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 IF-2B PF01008.17 KXG48471.1 - 1.4e-07 31.0 0.0 2.6e-06 26.8 0.0 2.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family Ndr PF03096.14 KXG48471.1 - 0.00019 20.2 0.0 0.0003 19.6 0.0 1.4 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 KXG48471.1 - 0.03 14.4 0.0 0.082 13.0 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein Homeodomain PF00046.29 KXG48471.1 - 0.089 12.7 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Homeodomain GFA PF04828.14 KXG48472.1 - 2.6e-20 72.5 0.2 3.9e-20 72.0 0.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Yippee-Mis18 PF03226.14 KXG48472.1 - 0.21 11.8 2.9 1 9.6 0.9 2.1 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PRK PF00485.18 KXG48473.1 - 2.7e-08 33.8 0.1 4.4e-07 29.8 0.1 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KXG48473.1 - 2.4e-06 28.1 0.0 3.4e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXG48473.1 - 7.5e-06 26.2 0.0 0.00016 21.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KXG48473.1 - 9.1e-05 22.2 0.0 0.00052 19.7 0.0 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KXG48473.1 - 0.00033 21.1 0.1 0.00069 20.0 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KXG48473.1 - 0.00038 19.8 0.1 0.0013 18.1 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 KXG48473.1 - 0.00052 20.4 0.0 0.00084 19.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KXG48473.1 - 0.0014 19.1 0.0 0.009 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXG48473.1 - 0.0019 18.5 0.0 0.0046 17.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain Thymidylate_kin PF02223.17 KXG48473.1 - 0.0026 17.5 0.1 0.082 12.6 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase KTI12 PF08433.10 KXG48473.1 - 0.0045 16.5 0.0 0.0064 16.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 T2SSE PF00437.20 KXG48473.1 - 0.0048 16.0 0.0 0.0077 15.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein MeaB PF03308.16 KXG48473.1 - 0.0056 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KXG48473.1 - 0.0057 16.4 0.0 0.0089 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KXG48473.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 KXG48473.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KXG48473.1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 KXG48473.1 - 0.028 14.3 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 KXG48473.1 - 0.045 13.6 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 NTPase ResIII PF04851.15 KXG48473.1 - 0.052 13.6 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KXG48473.1 - 0.052 13.3 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KXG48473.1 - 0.056 13.2 0.1 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF2075 PF09848.9 KXG48473.1 - 0.061 12.5 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.14 KXG48473.1 - 0.092 12.6 0.1 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 KXG48473.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KXG48473.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 KXG48473.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Hemerythrin PF01814.23 KXG48474.1 - 3.2e-10 40.7 0.3 5.3e-10 40.0 0.3 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Glyco_hydro_16 PF00722.21 KXG48475.1 - 4.2e-05 23.1 0.8 8.8e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 FAM196 PF15265.6 KXG48475.1 - 3.4 7.1 9.5 4.7 6.6 9.5 1.1 1 0 0 1 1 1 0 FAM196 family PAP1 PF08601.10 KXG48475.1 - 9.4 5.8 18.6 14 5.3 18.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 NAD_binding_4 PF07993.12 KXG48476.1 - 7.9e-29 100.6 0.0 1.5e-28 99.7 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXG48476.1 - 1.5e-25 89.7 0.1 4.7e-25 88.1 0.1 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KXG48476.1 - 4.3e-09 36.2 0.0 1.1e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXG48476.1 - 1.9e-08 34.5 0.0 4.8e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 KXG48476.1 - 0.015 14.4 0.0 0.032 13.4 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXG48476.1 - 0.044 12.8 0.0 0.13 11.3 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXG48476.1 - 0.15 11.1 0.0 0.85 8.7 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXG48476.1 - 0.21 11.4 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding AP_endonuc_2 PF01261.24 KXG48477.1 - 4.3e-28 98.2 0.7 6.8e-28 97.5 0.7 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Methyltransf_2 PF00891.18 KXG48478.1 - 1.8e-19 69.9 0.0 3.5e-19 68.9 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KXG48478.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain Dimerisation PF08100.11 KXG48478.1 - 0.045 13.8 0.6 0.17 11.9 0.6 2.0 1 1 0 1 1 1 0 Dimerisation domain BcrAD_BadFG PF01869.20 KXG48479.1 - 2.7e-15 56.6 0.5 7.7e-15 55.1 0.5 1.7 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.6 KXG48479.1 - 0.017 15.1 0.1 0.1 12.6 0.1 2.3 1 1 0 1 1 1 0 SIS domain MFS_1 PF07690.16 KXG48480.1 - 1.3e-17 63.8 33.2 1.3e-17 63.8 33.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXG48480.1 - 1.6e-09 37.7 3.2 1.6e-09 37.7 3.2 3.2 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 LapA_dom PF06305.11 KXG48480.1 - 0.28 11.0 0.0 0.28 11.0 0.0 2.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF3433 PF11915.8 KXG48484.1 - 2.6e-35 120.7 19.4 7.7e-19 67.9 1.9 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) IncD PF17628.2 KXG48484.1 - 5.8 6.7 5.7 35 4.2 0.0 3.1 3 0 0 3 3 3 0 Inclusion membrane protein D ApbA PF02558.16 KXG48485.1 - 2.6e-33 114.8 0.2 3.5e-33 114.4 0.2 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXG48485.1 - 4.9e-30 104.3 0.0 7.9e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Sacchrp_dh_NADP PF03435.18 KXG48485.1 - 0.054 13.7 0.3 0.19 12.0 0.1 2.1 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FMN_dh PF01070.18 KXG48486.1 - 8.2e-115 383.5 0.0 1e-114 383.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXG48486.1 - 4.7e-22 77.9 0.0 1.6e-20 73.0 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXG48486.1 - 1.5e-06 27.6 0.0 2.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXG48486.1 - 3.5e-05 23.0 0.4 0.00021 20.4 0.1 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KXG48486.1 - 0.023 14.0 0.2 6.5 6.0 0.0 2.6 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KXG48486.1 - 0.064 12.5 0.1 0.12 11.5 0.1 1.5 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase MR_MLE_C PF13378.6 KXG48487.1 - 1.9e-55 187.8 0.0 2.6e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KXG48487.1 - 4.1e-19 68.9 0.0 1.1e-18 67.5 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF1990 PF09348.10 KXG48487.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) Glyco_hydro_71 PF03659.14 KXG48488.1 - 2.1e-127 425.0 2.5 2.5e-127 424.8 2.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.6 KXG48488.1 - 0.14 12.2 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Apt1 PF10351.9 KXG48489.1 - 0.013 14.4 11.7 0.015 14.2 11.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Utp14 PF04615.13 KXG48489.1 - 0.016 13.9 9.4 0.018 13.7 9.4 1.1 1 0 0 1 1 1 0 Utp14 protein DUF3021 PF11457.8 KXG48489.1 - 0.076 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) GCOM2 PF15328.6 KXG48489.1 - 4.7 7.5 16.3 9.4 6.6 16.3 1.6 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 PI3K_1B_p101 PF10486.9 KXG48489.1 - 6.1 4.5 13.7 8 4.1 13.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Methyltransf_2 PF00891.18 KXG48490.1 - 8.8e-23 80.7 0.0 1.4e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KXG48490.1 - 0.0012 18.8 0.2 0.0027 17.7 0.2 1.7 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 KXG48490.1 - 0.0014 18.6 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.20 KXG48490.1 - 0.088 13.2 0.0 0.25 11.7 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator CIA30 PF08547.12 KXG48492.1 - 7.9e-40 136.5 0.0 1.3e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) MFS_1 PF07690.16 KXG48492.1 - 4.5e-37 127.8 50.0 5.5e-37 127.5 45.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG48492.1 - 3.4e-08 32.8 15.4 3.4e-08 32.8 15.4 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KXG48492.1 - 2.3e-05 23.9 6.1 2.3e-05 23.9 6.1 1.9 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB CBM_11 PF03425.13 KXG48492.1 - 0.02 14.7 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) Aminotran_5 PF00266.19 KXG48493.1 - 2.8e-17 62.8 0.0 3.7e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXG48493.1 - 0.0047 16.2 0.0 0.007 15.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II AA_permease PF00324.21 KXG48494.1 - 3e-120 402.1 34.2 3.7e-120 401.8 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG48494.1 - 7.3e-34 117.3 37.5 8.8e-34 117.0 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_76 PF03663.14 KXG48495.1 - 5.7e-141 470.3 27.0 7.1e-141 470.0 27.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Pkinase PF00069.25 KXG48495.1 - 3.6e-10 39.7 0.0 5.9e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48495.1 - 0.0031 16.8 0.0 0.0089 15.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase F-box-like PF12937.7 KXG48496.1 - 0.021 14.7 0.1 0.053 13.4 0.1 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KXG48496.1 - 0.042 13.7 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 KXG48496.1 - 0.12 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 F-box Ig_GlcNase PF18368.1 KXG48497.1 - 5e-31 107.0 1.0 5e-31 107.0 1.0 2.2 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 KXG48497.1 - 4.9e-14 52.9 0.9 2.1e-13 50.9 0.2 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 KXG48497.1 - 1.4e-07 32.0 0.1 5e-07 30.2 0.1 2.1 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2_N PF02837.18 KXG48497.1 - 6.1e-06 26.2 0.0 1.7e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Ig_mannosidase PF17753.1 KXG48497.1 - 0.0065 16.2 0.2 0.047 13.4 0.0 2.5 3 0 0 3 3 3 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 KXG48497.1 - 0.017 14.3 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_76 PF03663.14 KXG48498.1 - 6e-162 539.3 26.3 7e-162 539.1 26.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXG48498.1 - 7.1e-07 28.6 9.6 0.0073 15.4 0.0 3.2 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 ADH_N PF08240.12 KXG48499.1 - 7.6e-26 90.1 0.6 2e-25 88.8 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG48499.1 - 7.5e-18 64.8 1.6 1.5e-17 63.8 1.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG48499.1 - 0.00086 20.4 0.0 0.0015 19.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_1 PF00232.18 KXG48500.1 - 1.1e-76 258.1 0.3 1.4e-74 251.2 0.3 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Med17 PF10156.9 KXG48501.1 - 5.5e-100 335.2 0.0 8e-100 334.7 0.0 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex FAD_binding_3 PF01494.19 KXG48502.1 - 2.3e-78 263.9 0.0 1.4e-76 258.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXG48502.1 - 6.8e-42 144.3 2.0 3.5e-37 128.8 0.2 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Phe_hydrox_dim PF07976.12 KXG48502.1 - 2.3e-33 115.6 0.0 4.6e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 KXG48502.1 - 5.3e-10 39.4 2.9 0.00099 19.3 0.1 3.0 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG48502.1 - 9.9e-09 34.8 0.0 0.00045 19.6 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG48502.1 - 2.6e-07 30.2 0.3 0.0092 15.2 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.24 KXG48502.1 - 4.8e-05 22.6 4.2 0.0024 17.0 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KXG48502.1 - 0.00011 21.4 0.4 0.29 10.1 0.0 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 KXG48502.1 - 0.00035 21.1 0.1 7 7.3 0.1 3.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG48502.1 - 0.00036 19.9 0.0 0.0044 16.3 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG48502.1 - 0.00042 20.4 1.3 0.035 14.1 0.1 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KXG48502.1 - 0.00053 18.8 0.2 0.0039 16.0 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KXG48502.1 - 0.002 17.6 0.1 0.0043 16.5 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXG48502.1 - 0.0033 16.6 0.1 0.0054 15.9 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXG48502.1 - 0.0051 16.1 0.1 0.043 13.1 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 KXG48502.1 - 0.0058 15.8 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 KXG48502.1 - 0.009 15.3 2.3 0.66 9.2 0.1 3.4 5 0 0 5 5 5 1 Flavin containing amine oxidoreductase SE PF08491.10 KXG48502.1 - 0.14 11.2 0.0 3.6 6.6 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Dala_Dala_lig_C PF07478.13 KXG48503.1 - 3.5e-25 88.7 0.0 4.8e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KXG48503.1 - 0.00018 21.6 0.0 0.00037 20.6 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KXG48503.1 - 0.00045 19.8 0.0 0.0019 17.8 0.0 2.1 3 0 0 3 3 3 1 ATP-grasp domain GARS_A PF01071.19 KXG48503.1 - 0.006 16.4 0.0 0.0099 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PFK PF00365.20 KXG48504.1 - 1.3e-188 625.1 1.2 3e-103 345.1 0.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase XylR_N PF06505.11 KXG48504.1 - 0.035 13.8 0.4 3.1 7.6 0.0 2.8 3 0 0 3 3 3 0 Activator of aromatic catabolism DAGK_cat PF00781.24 KXG48504.1 - 0.12 12.0 0.0 0.5 10.0 0.1 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain ISN1 PF06437.11 KXG48505.1 - 9.4e-199 660.4 0.0 1.1e-198 660.3 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase DUF4646 PF15496.6 KXG48506.1 - 6.8e-09 36.4 0.1 3.7e-08 34.0 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) Erf4 PF10256.9 KXG48506.1 - 0.0091 16.1 0.0 0.022 14.9 0.0 1.6 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family CbtA PF09490.10 KXG48506.1 - 0.062 13.1 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Sugar_tr PF00083.24 KXG48507.1 - 1.1e-78 265.1 20.5 1.4e-78 264.8 20.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG48507.1 - 1.5e-14 53.7 52.6 1.6e-13 50.3 26.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2456 PF10445.9 KXG48507.1 - 0.12 12.4 5.4 2.8 8.1 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) MFS_1 PF07690.16 KXG48508.1 - 4.5e-26 91.6 28.6 4.5e-26 91.6 28.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF5422 PF17459.2 KXG48508.1 - 0.12 12.6 3.5 4.4 7.5 0.9 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5422) Fungal_trans PF04082.18 KXG48509.1 - 5e-09 35.6 0.6 9.2e-09 34.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 KXG48510.1 - 3.5e-64 216.1 51.0 2e-35 122.2 15.5 3.7 3 1 1 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KXG48510.1 - 3.2e-36 124.8 0.0 1.9e-18 67.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXG48510.1 - 7.8e-21 73.8 0.0 7.8e-21 73.8 0.0 3.5 4 0 0 4 4 3 1 CDR ABC transporter AAA_16 PF13191.6 KXG48510.1 - 3.5e-07 30.8 0.1 0.00058 20.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KXG48510.1 - 3.9e-07 30.2 0.0 0.39 10.5 0.0 3.7 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KXG48510.1 - 1.4e-06 27.7 29.1 2.4e-06 26.9 11.9 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KXG48510.1 - 3.6e-05 23.7 0.0 0.00097 19.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KXG48510.1 - 6.4e-05 23.5 0.0 0.047 14.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 KXG48510.1 - 0.00059 19.3 0.0 0.39 10.1 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXG48510.1 - 0.00077 19.2 0.1 0.024 14.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 KXG48510.1 - 0.0017 18.3 0.2 0.44 10.4 0.1 3.5 4 0 0 4 4 3 1 NACHT domain AAA_28 PF13521.6 KXG48510.1 - 0.0051 17.1 0.3 0.081 13.2 0.1 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KXG48510.1 - 0.0066 16.7 0.0 0.42 10.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KXG48510.1 - 0.012 15.7 0.0 4.3 7.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KXG48510.1 - 0.015 15.1 0.0 0.87 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXG48510.1 - 0.015 14.9 0.3 0.071 12.7 0.0 2.1 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.6 KXG48510.1 - 0.046 13.9 0.0 0.26 11.4 0.0 2.3 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 KXG48510.1 - 0.084 12.5 0.2 1.6 8.3 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KXG48510.1 - 0.14 12.1 0.0 13 5.7 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 KXG48510.1 - 0.17 12.4 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KXG48510.1 - 0.18 11.6 0.0 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SurE PF01975.17 KXG48511.1 - 3.7e-33 115.0 0.4 5.1e-33 114.5 0.4 1.1 1 0 0 1 1 1 1 Survival protein SurE NPP1 PF05630.11 KXG48512.1 - 5.4e-61 206.1 0.0 6.7e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Glyco_hydro_61 PF03443.14 KXG48513.1 - 7e-65 218.8 0.2 1.2e-64 218.0 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KXG48513.1 - 5.5e-13 48.6 8.9 5.5e-13 48.6 8.9 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain MFS_1 PF07690.16 KXG48514.1 - 2.5e-33 115.5 23.3 3.1e-33 115.1 23.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXG48514.1 - 0.069 11.7 27.2 0.009 14.6 11.3 2.9 2 2 1 3 3 3 0 MFS/sugar transport protein Glyco_hydro_88 PF07470.13 KXG48515.1 - 1.6e-96 323.4 4.0 1.9e-96 323.1 4.0 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KXG48515.1 - 0.0061 15.1 0.1 0.0079 14.7 0.1 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_76 PF03663.14 KXG48515.1 - 0.25 10.8 8.7 2.8 7.4 2.5 2.9 1 1 2 3 3 3 0 Glycosyl hydrolase family 76 Amidohydro_1 PF01979.20 KXG48516.1 - 1.6e-73 248.0 0.2 2e-73 247.7 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXG48516.1 - 3.7e-20 72.8 0.3 7.6e-16 58.6 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KXG48516.1 - 0.005 16.2 0.0 0.0083 15.5 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase Aldedh PF00171.22 KXG48517.1 - 1.1e-142 475.8 0.0 1.4e-142 475.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family P5CR_dimer PF14748.6 KXG48519.1 - 5.3e-35 119.8 1.9 5.5e-35 119.7 0.7 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KXG48519.1 - 5.4e-17 62.2 0.2 1.3e-16 60.9 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KXG48519.1 - 0.021 14.4 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KXG48519.1 - 0.027 14.5 0.2 0.1 12.6 0.2 2.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 KXG48519.1 - 0.062 13.5 0.2 0.33 11.1 0.1 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.17 KXG48519.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase zinc_ribbon_10 PF10058.9 KXG48520.1 - 2.7e-18 65.4 0.3 5e-18 64.6 0.3 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Ribonuclease_3 PF00636.26 KXG48521.1 - 4.5e-41 139.7 0.0 5.2e-23 81.7 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXG48521.1 - 1e-28 100.1 0.0 2.4e-13 50.4 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KXG48521.1 - 4e-24 84.6 0.0 1.2e-23 83.1 0.0 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 KXG48521.1 - 3.9e-16 59.4 0.1 1.5e-15 57.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXG48521.1 - 8.8e-09 35.4 0.1 1.2e-06 28.4 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KXG48521.1 - 0.0022 18.0 0.0 0.0077 16.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DIOX_N PF14226.6 KXG48522.1 - 1.3e-20 74.3 0.0 2.1e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG48522.1 - 3e-12 46.9 0.0 4.7e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily peroxidase PF00141.23 KXG48524.1 - 6.2e-83 278.0 0.0 6e-44 150.4 0.0 2.3 2 0 0 2 2 2 2 Peroxidase MFS_1 PF07690.16 KXG48527.1 - 1.6e-23 83.2 34.2 1.6e-23 83.2 34.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Avian_gp85 PF03708.14 KXG48527.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Avian retrovirus envelope protein, gp85 M20_dimer PF07687.14 KXG48528.1 - 1.7e-09 37.6 0.0 5.5e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KXG48528.1 - 6.1e-07 29.3 0.1 1e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 GMC_oxred_N PF00732.19 KXG48531.1 - 1.2e-55 189.0 0.0 1.6e-55 188.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG48531.1 - 2e-30 106.2 0.0 3.2e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KXG48531.1 - 4.3e-06 26.5 0.1 0.0036 16.9 0.0 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXG48531.1 - 4.8e-06 25.9 0.1 7.4e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXG48531.1 - 3.5e-05 23.2 0.3 0.18 11.0 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXG48531.1 - 0.00031 20.0 0.1 0.55 9.3 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KXG48531.1 - 0.0004 20.6 0.2 0.0013 18.9 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXG48531.1 - 0.00049 18.9 0.1 0.061 12.0 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 KXG48531.1 - 0.0029 16.9 0.1 0.0088 15.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CBM_11 PF03425.13 KXG48531.1 - 0.0035 17.2 0.1 0.0064 16.4 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) FAD_binding_2 PF00890.24 KXG48531.1 - 0.012 14.8 0.3 0.048 12.7 0.0 2.1 2 1 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KXG48531.1 - 0.15 12.1 0.0 0.41 10.6 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KXG48531.1 - 1.3 8.3 3.1 2.1 7.6 0.3 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase bZIP_1 PF00170.21 KXG48533.1 - 5.6e-10 39.2 10.6 1.9e-08 34.2 9.0 2.6 2 1 0 2 2 2 1 bZIP transcription factor BLOC1_2 PF10046.9 KXG48533.1 - 0.035 14.4 0.6 0.068 13.5 0.6 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_2 PF07716.15 KXG48533.1 - 0.11 12.6 13.0 0.55 10.3 7.3 3.0 2 1 1 3 3 3 0 Basic region leucine zipper DUF2205 PF10224.9 KXG48533.1 - 0.33 11.0 2.2 0.79 9.8 2.2 1.6 1 0 0 1 1 1 0 Short coiled-coil protein Anoctamin PF04547.12 KXG48534.1 - 1e-118 397.1 4.3 1.2e-118 396.8 4.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel ECF_trnsprt PF12822.7 KXG48534.1 - 0.062 13.4 11.6 0.048 13.8 1.1 3.2 1 1 1 2 2 2 0 ECF transporter, substrate-specific component GRIP PF01465.20 KXG48535.1 - 6.4e-17 61.2 0.2 1.5e-16 60.0 0.2 1.7 1 0 0 1 1 1 1 GRIP domain Acetyltransf_1 PF00583.25 KXG48535.1 - 1.4e-14 54.3 0.0 3.5e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Spc7 PF08317.11 KXG48535.1 - 5.8e-09 35.3 144.8 0.00094 18.1 19.5 8.3 2 2 6 8 8 8 5 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KXG48535.1 - 4.3e-08 33.3 158.8 6.5e-05 23.0 11.0 10.1 3 2 6 9 9 9 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KXG48535.1 - 2.4e-07 30.3 143.1 0.049 13.0 11.3 9.8 3 2 7 10 10 10 6 Growth-arrest specific micro-tubule binding Acetyltransf_7 PF13508.7 KXG48535.1 - 4.1e-06 27.1 0.0 8.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG48535.1 - 4.9e-06 26.4 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein DUF3584 PF12128.8 KXG48535.1 - 5.2e-06 24.3 47.7 5.2e-06 24.3 47.7 5.8 3 2 3 6 6 6 2 Protein of unknown function (DUF3584) EzrA PF06160.12 KXG48535.1 - 0.00011 20.6 109.8 0.00032 19.0 47.5 4.8 2 2 1 4 4 4 2 Septation ring formation regulator, EzrA Acetyltransf_10 PF13673.7 KXG48535.1 - 0.0002 21.3 0.0 0.00059 19.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fez1 PF06818.15 KXG48535.1 - 0.00044 20.8 144.5 0.18 12.3 21.2 8.4 1 1 5 6 6 5 2 Fez1 DHR10 PF18595.1 KXG48535.1 - 0.0008 19.5 12.3 0.0008 19.5 12.3 11.7 6 2 5 12 12 10 2 Designed helical repeat protein 10 domain Fib_alpha PF08702.10 KXG48535.1 - 0.0024 18.0 90.3 0.0034 17.6 13.8 8.9 3 3 3 7 7 7 3 Fibrinogen alpha/beta chain family Leu_zip PF15294.6 KXG48535.1 - 0.0026 17.3 22.4 0.0026 17.3 22.4 6.2 2 2 3 6 6 6 2 Leucine zipper DUF4201 PF13870.6 KXG48535.1 - 0.0037 17.0 4.4 0.0037 17.0 4.4 11.1 3 3 8 11 11 10 4 Domain of unknown function (DUF4201) CC2-LZ PF16516.5 KXG48535.1 - 0.0044 17.3 7.3 0.0044 17.3 7.3 12.3 5 3 6 12 12 12 3 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FPP PF05911.11 KXG48535.1 - 0.018 13.2 140.4 0.0084 14.4 19.4 6.0 2 2 4 6 6 6 0 Filament-like plant protein, long coiled-coil Baculo_PEP_C PF04513.12 KXG48535.1 - 0.021 14.9 50.8 1.4 9.0 0.9 7.2 3 2 3 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus Acetyltransf_3 PF13302.7 KXG48535.1 - 0.066 13.9 0.0 0.27 11.9 0.0 2.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Golgin_A5 PF09787.9 KXG48535.1 - 0.082 12.4 140.1 0.17 11.3 21.3 7.4 2 2 5 7 7 7 0 Golgin subfamily A member 5 APG6_N PF17675.1 KXG48535.1 - 0.15 12.6 178.4 0.051 14.1 9.6 11.9 4 2 9 13 13 11 0 Apg6 coiled-coil region HMMR_N PF15905.5 KXG48535.1 - 0.22 10.9 140.5 0.78 9.1 37.8 7.4 2 2 4 7 7 7 0 Hyaluronan mediated motility receptor N-terminal Filament PF00038.21 KXG48535.1 - 0.73 9.4 129.7 0.4 10.2 43.2 8.1 2 2 3 5 5 5 0 Intermediate filament protein MAD PF05557.13 KXG48535.1 - 0.92 7.8 139.1 0.024 13.0 10.4 5.5 2 2 3 5 5 5 0 Mitotic checkpoint protein AAA_13 PF13166.6 KXG48535.1 - 1.2 7.7 110.7 0.19 10.4 23.3 5.6 1 1 2 4 4 4 0 AAA domain DUF4763 PF15960.5 KXG48535.1 - 1.3 8.2 105.7 0.008 15.5 16.4 8.0 2 2 6 8 8 8 0 Domain of unknown function (DUF4763) ATG16 PF08614.11 KXG48535.1 - 3.9 7.6 172.6 6.2 7.0 4.4 9.8 2 1 5 8 8 8 0 Autophagy protein 16 (ATG16) DUF812 PF05667.11 KXG48535.1 - 4.5 6.0 141.9 0.49 9.2 9.8 7.1 1 1 6 7 7 7 0 Protein of unknown function (DUF812) cNMP_binding PF00027.29 KXG48536.1 - 1.7e-30 104.9 0.4 1.2e-18 67.0 0.0 5.7 5 1 1 6 6 6 4 Cyclic nucleotide-binding domain Patatin PF01734.22 KXG48536.1 - 6.7e-17 62.3 5.8 3.7e-15 56.7 5.8 2.7 1 1 0 1 1 1 1 Patatin-like phospholipase MARVEL PF01284.23 KXG48537.1 - 9.6e-16 58.1 7.0 1.2e-15 57.7 7.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF202 PF02656.15 KXG48537.1 - 0.068 13.6 4.5 13 6.3 4.5 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Ribosomal_S12 PF17487.2 KXG48537.1 - 0.069 13.9 1.4 0.069 13.9 1.4 1.9 3 0 0 3 3 3 0 Ribosomal protein S12 DUF2615 PF11027.8 KXG48537.1 - 0.24 11.6 0.0 0.6 10.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Actin PF00022.19 KXG48538.1 - 1.6e-53 181.8 0.0 9.2e-29 100.3 0.0 2.3 2 1 0 2 2 2 2 Actin DASH_Dad4 PF08650.10 KXG48539.1 - 2.6e-32 110.6 8.4 2.8e-32 110.5 8.4 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.17 KXG48539.1 - 0.05 13.8 0.3 0.052 13.7 0.3 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Biotin_carb_C PF02785.19 KXG48539.1 - 0.12 12.5 0.1 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain YL1_C PF08265.11 KXG48540.1 - 1.1e-15 57.1 0.3 2e-15 56.2 0.3 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Got1 PF04178.12 KXG48541.1 - 3.5e-13 50.0 13.7 4.5e-13 49.6 13.7 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family PIRT PF15099.6 KXG48541.1 - 9.2 5.9 7.2 82 2.8 7.2 2.1 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family Profilin PF00235.19 KXG48542.1 - 2.6e-32 111.8 0.2 2.8e-32 111.7 0.2 1.0 1 0 0 1 1 1 1 Profilin Sec63 PF02889.16 KXG48544.1 - 1.4e-132 440.6 0.0 7.6e-81 271.0 0.0 2.5 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KXG48544.1 - 1.4e-51 174.8 0.2 5.7e-26 91.3 0.3 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 KXG48544.1 - 1.4e-22 80.5 0.0 3.1e-11 43.6 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXG48544.1 - 1.9e-17 63.6 0.1 6.5e-07 29.7 0.0 4.2 4 2 0 4 4 4 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXG48544.1 - 2.6e-08 34.2 0.2 0.0008 19.7 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXG48544.1 - 4.4e-07 29.8 0.1 0.01 15.6 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KXG48544.1 - 4.5e-05 23.8 0.4 0.0094 16.3 0.4 2.6 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 KXG48544.1 - 0.00091 19.4 0.1 0.0027 17.9 0.1 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain IstB_IS21 PF01695.17 KXG48544.1 - 0.053 13.3 0.3 4.5 7.0 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein TniB PF05621.11 KXG48544.1 - 0.071 12.5 0.7 16 4.8 0.0 3.4 4 0 0 4 4 4 0 Bacterial TniB protein Synaptobrevin PF00957.21 KXG48545.1 - 6.6e-15 54.7 0.7 1.1e-14 54.0 0.7 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KXG48545.1 - 3.8e-12 46.1 0.0 8e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain 4HBT_3 PF13622.6 KXG48546.1 - 1.8e-60 205.3 0.7 2.1e-60 205.0 0.7 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KXG48546.1 - 1.3e-21 76.8 0.0 1.9e-15 56.9 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT PF03061.22 KXG48546.1 - 0.032 14.6 0.0 0.33 11.3 0.0 2.3 2 0 0 2 2 2 0 Thioesterase superfamily HPP PF04982.13 KXG48547.1 - 2e-40 137.8 7.5 2.8e-40 137.3 7.5 1.3 1 0 0 1 1 1 1 HPP family BPD_transp_2 PF02653.16 KXG48547.1 - 0.014 14.6 2.1 0.017 14.3 2.1 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component CbiM PF01891.16 KXG48547.1 - 0.027 14.3 4.3 0.96 9.2 0.0 2.2 1 1 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region DUF4131 PF13567.6 KXG48547.1 - 0.36 10.5 9.2 2.3 7.8 1.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4231 PF14015.6 KXG48547.1 - 0.5 10.9 0.1 0.5 10.9 0.1 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Cupin_2 PF07883.11 KXG48548.1 - 5.3e-10 38.9 0.0 7e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXG48548.1 - 9e-05 22.1 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_7 PF12973.7 KXG48548.1 - 0.036 14.0 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 ChrR Cupin-like domain DUF4437 PF14499.6 KXG48548.1 - 0.046 12.8 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) DMSP_lyase PF16867.5 KXG48548.1 - 0.057 13.1 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Sugar_tr PF00083.24 KXG48549.1 - 1.2e-61 209.0 30.7 1.5e-61 208.7 30.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG48549.1 - 2e-15 56.6 46.5 2.4e-15 56.3 39.6 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXG48549.1 - 0.0019 16.8 7.0 0.0019 16.8 7.0 3.9 2 2 2 4 4 4 2 MFS/sugar transport protein DUF872 PF05915.12 KXG48549.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.7 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF2207 PF09972.9 KXG48550.1 - 0.0014 17.5 0.1 0.0014 17.5 0.1 2.4 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) SUR7 PF06687.12 KXG48551.1 - 0.073 12.7 2.5 0.15 11.7 1.0 1.9 2 0 0 2 2 2 0 SUR7/PalI family T4SS_CagC PF16943.5 KXG48551.1 - 0.21 11.7 5.7 0.17 12.1 0.8 2.5 1 1 1 2 2 2 0 Cag pathogenicity island, type IV secretory system DUF3671 PF12420.8 KXG48551.1 - 2.3 8.3 4.5 80 3.4 4.5 2.4 1 1 0 1 1 1 0 Protein of unknown function FAD_binding_4 PF01565.23 KXG48552.1 - 1.2e-23 83.4 0.0 1.8e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG48552.1 - 1.4e-06 28.3 0.8 5.3e-06 26.4 0.1 2.3 2 0 0 2 2 2 1 Berberine and berberine like SSF PF00474.17 KXG48553.1 - 4.1e-24 85.2 31.4 6.2e-24 84.6 31.4 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Methyltransf_25 PF13649.6 KXG48553.1 - 5.3e-17 62.3 0.0 1.5e-16 60.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG48553.1 - 4.9e-16 59.2 0.0 2.1e-15 57.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG48553.1 - 1.9e-14 53.8 0.0 3.1e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG48553.1 - 1.9e-14 54.2 0.0 4.1e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG48553.1 - 3.6e-14 52.9 0.0 6.3e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXG48553.1 - 0.00092 18.6 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KXG48553.1 - 0.0017 17.3 0.0 0.004 16.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DUF5394 PF17372.2 KXG48553.1 - 0.0044 16.6 1.2 0.0047 16.5 0.0 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF5394) Ubie_methyltran PF01209.18 KXG48553.1 - 0.0051 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KXG48553.1 - 0.012 15.3 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KXG48553.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KXG48553.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXG48553.1 - 0.05 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PulG PF11773.8 KXG48553.1 - 0.15 11.9 0.1 23 4.9 0.1 2.6 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin Bac_luciferase PF00296.20 KXG48554.1 - 5.8e-54 183.6 0.0 9.2e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_N PF08240.12 KXG48555.1 - 1.5e-06 28.1 0.0 2.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2OG-FeII_Oxy_2 PF13532.6 KXG48556.1 - 4.2e-26 92.3 0.0 7.2e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3431 PF11913.8 KXG48557.1 - 2.4e-82 275.9 0.0 3.1e-82 275.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Ras PF00071.22 KXG48559.1 - 0.096 12.3 0.0 9.5 5.8 0.0 2.1 2 0 0 2 2 2 0 Ras family Sugar_tr PF00083.24 KXG48560.1 - 1.3e-102 344.0 24.9 1.5e-102 343.8 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG48560.1 - 2.3e-24 86.0 36.7 4e-15 55.6 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.12 KXG48560.1 - 0.034 14.3 4.1 0.25 11.5 0.0 3.1 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 FMN_dh PF01070.18 KXG48561.1 - 5.2e-122 407.2 0.1 6.3e-122 406.9 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXG48561.1 - 4.7e-23 81.1 0.0 9.3e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXG48561.1 - 9e-08 31.6 0.0 1.5e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KXG48561.1 - 6.8e-05 22.4 0.1 0.00012 21.6 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXG48561.1 - 0.00014 21.0 0.5 0.00038 19.6 0.1 1.9 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KXG48561.1 - 0.027 13.8 0.0 6.2 6.1 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 KXG48561.1 - 0.044 12.9 0.2 1.1 8.4 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF561) His_biosynth PF00977.21 KXG48561.1 - 0.099 12.1 2.2 1.1 8.6 0.1 2.4 2 1 0 3 3 3 0 Histidine biosynthesis protein G3P_antiterm PF04309.12 KXG48561.1 - 0.15 11.5 0.0 13 5.1 0.0 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Metallophos PF00149.28 KXG48562.1 - 1.1e-10 42.4 0.0 2.5e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXG48562.1 - 5.2e-05 23.5 1.3 0.0014 18.8 1.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 KXG48563.1 - 9.1e-42 143.2 0.2 2.5e-22 79.5 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48563.1 - 7.9e-15 54.8 0.5 3e-10 39.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXG48563.1 - 0.096 11.4 0.6 0.12 11.1 0.3 1.5 1 1 0 1 1 1 0 Fungal protein kinase DNA_binding_1 PF01035.20 KXG48564.1 - 2.5e-23 82.0 0.1 3.2e-23 81.7 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Bud13 PF09736.9 KXG48565.1 - 2.3e-48 164.3 8.8 2.3e-48 164.3 8.8 2.8 2 1 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex SPATIAL PF15256.6 KXG48565.1 - 0.2 12.0 4.1 0.34 11.2 4.1 1.4 1 0 0 1 1 1 0 SPATIAL DUF2477 PF10631.9 KXG48565.1 - 0.29 11.8 0.6 1.9 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) RR_TM4-6 PF06459.12 KXG48565.1 - 2.6 7.8 14.0 4.8 6.9 14.0 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Brr6_like_C_C PF10104.9 KXG48566.1 - 6.3e-38 129.6 0.2 9.9e-38 128.9 0.2 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain PBP1_TM PF14812.6 KXG48566.1 - 0.054 13.9 3.6 0.096 13.1 1.8 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pex14_N PF04695.13 KXG48566.1 - 0.24 12.0 0.0 0.24 12.0 0.0 3.3 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MFS_1 PF07690.16 KXG48567.1 - 6.8e-31 107.5 50.3 1.1e-30 106.8 50.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG48567.1 - 1.2e-08 34.3 35.7 5e-08 32.2 10.4 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter Glyco_transf_20 PF00982.21 KXG48568.1 - 6.5e-131 437.3 0.0 3.1e-116 388.9 0.0 2.1 1 1 1 2 2 2 2 Glycosyltransferase family 20 DUF693 PF05113.13 KXG48568.1 - 0.0052 16.1 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF693) Glycos_transf_1 PF00534.20 KXG48568.1 - 0.015 14.8 0.4 0.24 10.9 0.4 2.4 1 1 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KXG48568.1 - 0.031 14.7 0.0 0.099 13.0 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferases group 1 AA_permease PF00324.21 KXG48569.1 - 1e-134 449.8 42.8 1.2e-134 449.5 42.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG48569.1 - 4.3e-33 114.8 46.7 5e-33 114.5 46.7 1.0 1 0 0 1 1 1 1 Amino acid permease Ribonuclease PF00545.20 KXG48570.1 - 4.6e-09 36.9 0.1 6e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 ribonuclease MF_alpha_N PF05436.11 KXG48570.1 - 0.11 12.4 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus GST_N_3 PF13417.6 KXG48571.1 - 4.8e-13 49.3 0.1 1.1e-12 48.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXG48571.1 - 1.4e-12 47.8 0.0 8.9e-12 45.2 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXG48571.1 - 3.3e-09 36.8 0.1 5.1e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXG48571.1 - 5.6e-09 36.2 0.1 1.1e-08 35.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXG48571.1 - 2.5e-08 34.0 0.1 4.2e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXG48571.1 - 0.00058 20.4 0.0 0.0053 17.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXG48571.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KXG48571.1 - 0.0022 18.7 0.0 0.028 15.2 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase N-terminal domain Methyltransf_31 PF13847.6 KXG48572.1 - 2.2e-28 99.0 0.0 2.8e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG48572.1 - 1.5e-24 86.4 0.0 2.4e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG48572.1 - 1.9e-24 86.2 0.0 3.2e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG48572.1 - 8.9e-19 67.7 0.0 1.2e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXG48572.1 - 2.2e-15 57.2 0.0 3.1e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG48572.1 - 8.7e-15 54.9 0.0 1.3e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXG48572.1 - 2.1e-07 30.6 0.0 3.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.12 KXG48572.1 - 4.3e-07 29.7 0.0 5.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KXG48572.1 - 5.2e-06 26.1 0.0 7.2e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 KXG48572.1 - 0.00042 20.0 0.0 0.00058 19.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.19 KXG48572.1 - 0.00071 19.4 0.0 0.00091 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 KXG48572.1 - 0.0066 15.4 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 KXG48572.1 - 0.0093 15.9 0.0 0.017 15.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 KXG48572.1 - 0.022 13.9 0.0 0.032 13.3 0.0 1.3 1 1 0 1 1 1 0 DREV methyltransferase TehB PF03848.14 KXG48572.1 - 0.025 14.0 0.0 0.034 13.6 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 KXG48572.1 - 0.043 13.7 0.0 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_32 PF13679.6 KXG48572.1 - 0.044 13.8 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 KXG48572.1 - 0.051 13.7 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_29 PF03141.16 KXG48572.1 - 0.098 11.2 0.0 0.15 10.6 0.0 1.4 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 KXG48572.1 - 0.14 11.2 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CMAS PF02353.20 KXG48572.1 - 0.17 11.1 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase WW PF00397.26 KXG48573.1 - 2.8e-07 30.5 1.2 2.8e-07 30.5 1.2 2.3 2 0 0 2 2 2 1 WW domain SARAF PF06682.12 KXG48573.1 - 0.45 10.1 8.4 0.2 11.2 6.8 1.3 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Na_Ca_ex PF01699.24 KXG48574.1 - 1.1e-39 135.8 36.9 4.2e-20 72.3 15.8 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4672 PF15716.5 KXG48574.1 - 2.7 7.6 7.2 5 6.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4672) CorA PF01544.18 KXG48575.1 - 1.2e-35 123.3 0.0 1.6e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Anoctamin PF04547.12 KXG48576.1 - 4.8e-94 315.7 3.9 5.8e-94 315.5 3.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF3368 PF11848.8 KXG48576.1 - 0.17 11.7 0.0 6.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) UbiA PF01040.18 KXG48576.1 - 0.62 9.3 6.2 0.087 12.1 1.5 1.9 2 0 0 2 2 2 0 UbiA prenyltransferase family Tri3 PF07428.11 KXG48577.1 - 3.4e-06 26.2 0.0 3.2e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 DUF5454 PF17535.2 KXG48577.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5454) Transp_cyt_pur PF02133.15 KXG48579.1 - 1.2e-77 261.6 40.9 1.4e-77 261.4 40.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ldr_toxin PF13940.6 KXG48579.1 - 0.083 13.0 4.1 0.061 13.4 1.2 2.5 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system DUF3784 PF12650.7 KXG48579.1 - 0.33 11.2 0.0 0.33 11.2 0.0 6.1 7 1 1 8 8 8 0 Domain of unknown function (DUF3784) TauD PF02668.16 KXG48580.1 - 7.7e-27 94.8 0.0 9.9e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXG48580.1 - 0.009 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 CsiD PEP_mutase PF13714.6 KXG48581.1 - 6.3e-36 124.0 0.0 7.4e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KXG48581.1 - 8.2e-19 67.5 0.1 1.1e-18 67.0 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Dynactin_p62 PF05502.13 KXG48581.1 - 0.097 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Dynactin p62 family Fungal_trans PF04082.18 KXG48582.1 - 4e-19 68.7 2.4 1.5e-18 66.8 2.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG48582.1 - 4.9e-08 33.0 11.3 8.5e-08 32.2 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polysacc_deac_1 PF01522.21 KXG48583.1 - 8.4e-10 38.6 0.0 1.4e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Amidase PF01425.21 KXG48584.1 - 1.1e-83 281.7 0.2 1.4e-83 281.4 0.2 1.0 1 0 0 1 1 1 1 Amidase ThrE PF06738.12 KXG48585.1 - 2.4e-67 226.8 22.6 1.5e-62 211.1 4.4 3.0 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KXG48585.1 - 5.8e-13 49.1 7.9 5.8e-13 49.1 7.9 2.7 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE Pectate_lyase_3 PF12708.7 KXG48586.1 - 3.9e-54 183.8 13.7 2.1e-45 155.2 3.8 3.0 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KXG48586.1 - 0.01 15.5 1.4 0.041 13.6 0.0 2.5 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase MACPF PF01823.19 KXG48587.1 - 0.00043 20.5 2.2 0.00095 19.3 1.1 1.9 1 1 1 2 2 2 1 MAC/Perforin domain DUF5114 PF17141.4 KXG48587.1 - 0.034 14.7 0.1 0.13 12.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5114) Phasin PF05597.11 KXG48588.1 - 0.067 13.2 0.5 0.089 12.8 0.5 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF883 PF05957.13 KXG48588.1 - 8.5 7.1 7.6 7.3 7.3 0.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) AA_permease_2 PF13520.6 KXG48590.1 - 1.6e-73 247.9 43.6 2e-73 247.7 43.6 1.0 1 0 0 1 1 1 1 Amino acid permease CopD PF05425.13 KXG48590.1 - 0.05 14.0 0.3 0.05 14.0 0.3 4.3 3 1 2 5 5 5 0 Copper resistance protein D Innexin PF00876.18 KXG48590.1 - 2.2 7.5 5.2 0.18 11.1 0.1 1.7 2 0 0 2 2 2 0 Innexin VIT1 PF01988.19 KXG48590.1 - 7.4 6.4 11.0 0.26 11.1 0.6 3.1 3 0 0 3 3 3 0 VIT family MIP PF00230.20 KXG48591.1 - 3.2e-37 128.4 7.2 8e-37 127.1 7.2 1.5 1 1 0 1 1 1 1 Major intrinsic protein NAD_binding_1 PF00175.21 KXG48592.1 - 1.5e-14 54.5 0.0 2.8e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KXG48592.1 - 1.8e-07 31.7 0.0 5e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.24 KXG48592.1 - 6.7e-06 26.4 0.0 1.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXG48592.1 - 2.6e-05 24.4 0.0 0.00014 22.0 0.0 2.1 2 1 1 3 3 3 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 KXG48592.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Protoglobin FAD_binding_8 PF08022.12 KXG48592.1 - 0.066 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 FAD-binding domain Guanylate_kin PF00625.21 KXG48592.1 - 0.2 11.3 0.0 0.44 10.2 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase NmrA PF05368.13 KXG48593.1 - 2.1e-19 70.0 0.0 2.5e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG48593.1 - 1.5e-14 54.3 0.0 2.3e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXG48593.1 - 0.0015 17.6 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ApbA PF02558.16 KXG48593.1 - 0.0093 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KXG48593.1 - 0.019 15.2 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HLH PF00010.26 KXG48595.1 - 7.6e-10 38.6 0.0 1.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 KXG48595.1 - 0.033 14.4 0.9 0.064 13.5 0.9 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Peptidase_S64 PF08192.11 KXG48595.1 - 5.3 5.4 11.2 7.1 5.0 11.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 AA_permease_2 PF13520.6 KXG48596.1 - 3.8e-60 203.9 50.0 4.7e-60 203.6 50.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG48596.1 - 1e-22 80.4 40.1 1.3e-22 80.1 40.1 1.1 1 0 0 1 1 1 1 Amino acid permease Pro-kuma_activ PF09286.11 KXG48597.1 - 5.7e-37 127.2 0.1 2.5e-36 125.1 0.1 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXG48597.1 - 1.8e-11 43.9 0.0 4.1e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Subtilase family adh_short PF00106.25 KXG48598.1 - 4.7e-11 42.5 0.0 2.4e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase GHD PF17834.1 KXG48598.1 - 0.0095 16.0 0.0 0.081 13.0 0.0 2.3 2 0 0 2 2 2 1 Beta-sandwich domain in beta galactosidase KR PF08659.10 KXG48598.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 KR domain Alpha_GJ PF03229.13 KXG48599.1 - 0.19 12.3 14.3 1 9.9 7.9 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF4241 PF14025.6 KXG48599.1 - 0.25 11.6 1.9 0.48 10.7 0.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4241) Sugar_tr PF00083.24 KXG48600.1 - 7.7e-110 367.8 25.6 1.1e-109 367.4 25.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG48600.1 - 9.4e-28 97.1 37.6 1.8e-18 66.6 12.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG48600.1 - 0.0023 16.4 3.7 0.0041 15.6 3.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXG48601.1 - 2e-25 89.6 8.7 2.5e-24 86.0 8.7 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG48601.1 - 3.2e-19 69.1 16.3 4.2e-19 68.7 16.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 KXG48602.1 - 3e-05 24.2 0.0 6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pkinase PF00069.25 KXG48603.1 - 2.1e-23 83.0 0.0 1e-22 80.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48603.1 - 3.9e-06 26.3 0.0 1.5e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3533 PF12051.8 KXG48604.1 - 2.2e-129 431.7 10.2 2.6e-129 431.5 10.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ECH_1 PF00378.20 KXG48606.1 - 3.5e-43 147.7 0.0 4.6e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXG48606.1 - 5.7e-26 91.8 0.0 8.5e-24 84.7 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase RAC_head PF16717.5 KXG48607.1 - 2e-29 102.4 3.7 2e-29 102.4 3.7 3.3 2 1 0 2 2 2 1 Ribosome-associated complex head domain DnaJ PF00226.31 KXG48607.1 - 2.9e-16 59.3 0.4 2.9e-16 59.3 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain AAA_23 PF13476.6 KXG48607.1 - 1.1 9.7 16.8 0.25 11.8 12.9 1.8 2 0 0 2 2 2 0 AAA domain LMBR1 PF04791.16 KXG48607.1 - 2.3 7.0 8.0 2.4 7.0 8.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Complex1_LYR PF05347.15 KXG48608.1 - 6.1e-06 26.2 0.1 9.9e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RRM_1 PF00076.22 KXG48609.1 - 2.3e-08 33.7 0.0 4.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXG48609.1 - 0.0041 17.1 0.0 0.0067 16.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Sterol_MT_C PF08498.10 KXG48610.1 - 6.6e-27 93.6 0.1 1.5e-26 92.4 0.1 1.6 2 0 0 2 2 2 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KXG48610.1 - 2e-21 76.4 0.0 3.4e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG48610.1 - 2.8e-19 69.6 0.0 5.1e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG48610.1 - 1.7e-17 63.6 0.0 2.6e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG48610.1 - 5.6e-11 42.6 0.0 8.7e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXG48610.1 - 1.3e-10 41.0 0.1 1.9e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KXG48610.1 - 4.7e-10 39.2 0.0 7.6e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXG48610.1 - 6.6e-09 36.4 0.0 1.4e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KXG48610.1 - 0.00035 19.2 0.0 0.00047 18.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_15 PF09445.10 KXG48610.1 - 0.00043 19.9 0.1 0.00075 19.1 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KXG48610.1 - 0.0011 18.4 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KXG48610.1 - 0.0012 18.6 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KXG48610.1 - 0.004 16.8 0.0 0.0078 15.8 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KXG48610.1 - 0.0046 16.5 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 KXG48610.1 - 0.007 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 KXG48610.1 - 0.038 14.0 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KXG48610.1 - 0.053 12.9 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Ank_2 PF12796.7 KXG48611.1 - 1.7e-44 150.3 0.1 1.6e-11 44.6 0.0 6.8 4 2 3 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.30 KXG48611.1 - 6.4e-34 114.9 0.3 3.5e-07 30.4 0.0 9.9 7 2 2 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 KXG48611.1 - 7.4e-30 99.7 2.1 0.00042 20.5 0.0 10.9 11 0 0 11 11 11 6 Ankyrin repeat Ank_4 PF13637.6 KXG48611.1 - 6.6e-29 99.9 8.4 3.7e-05 24.2 0.0 10.1 7 4 3 10 10 10 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG48611.1 - 9.9e-23 79.9 5.8 7.8e-06 26.1 0.0 9.2 8 2 2 10 10 10 4 Ankyrin repeats (many copies) Phosphoesterase PF04185.14 KXG48612.1 - 6.1e-35 121.1 0.8 2.7e-34 118.9 0.8 1.9 1 1 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.23 KXG48612.1 - 0.0045 16.4 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 Sulfatase HIF-1a_CTAD PF08778.10 KXG48612.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain Sugar_tr PF00083.24 KXG48613.1 - 3.2e-111 372.4 24.8 3.7e-111 372.2 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG48613.1 - 5.7e-18 65.0 38.2 6.8e-12 45.0 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KXG48614.1 - 3.3e-46 157.8 21.5 3.3e-46 157.8 21.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG48614.1 - 1.7e-14 53.6 0.4 1.7e-14 53.6 0.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXG48614.1 - 4.3e-07 28.8 1.5 7.9e-07 27.9 1.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TRIQK PF15168.6 KXG48614.1 - 0.14 12.1 0.3 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family OATP PF03137.20 KXG48614.1 - 1.3 7.2 5.0 0.42 8.8 0.3 2.3 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_M35 PF02102.15 KXG48615.1 - 0.057 12.3 0.0 0.072 11.9 0.0 1.1 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Fungal_trans_2 PF11951.8 KXG48617.1 - 2.6e-31 108.8 0.9 6e-31 107.6 0.7 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KXG48618.1 - 1.6e-54 184.9 0.1 1.9e-54 184.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG48618.1 - 1.6e-40 138.7 0.1 1.9e-40 138.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG48618.1 - 3.2e-10 40.2 0.5 4.6e-10 39.7 0.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXG48618.1 - 0.00039 20.4 0.2 0.00063 19.7 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KXG48618.1 - 0.0027 17.1 0.6 0.0059 15.9 0.6 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sacchrp_dh_NADP PF03435.18 KXG48618.1 - 0.0053 17.0 0.1 0.01 16.1 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ChuX_HutX PF06228.13 KXG48618.1 - 0.0066 16.2 0.0 0.88 9.4 0.0 2.3 1 1 1 2 2 2 1 Haem utilisation ChuX/HutX Epimerase PF01370.21 KXG48618.1 - 0.023 14.2 0.1 0.039 13.4 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXG48618.1 - 0.041 13.0 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Aldedh PF00171.22 KXG48619.1 - 3.3e-130 434.7 0.0 4.3e-130 434.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GATase PF00117.28 KXG48619.1 - 3.3e-08 33.5 0.0 6.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KXG48619.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Phage_HK97_TLTM PF06120.11 KXG48619.1 - 0.0043 16.3 0.1 0.01 15.1 0.1 1.6 1 0 0 1 1 1 1 Tail length tape measure protein Peptidase_C26 PF07722.13 KXG48619.1 - 0.005 16.6 0.1 0.031 14.0 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KXG48619.1 - 0.069 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family SNO PF01174.19 KXG48619.1 - 0.07 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 SNO glutamine amidotransferase family DnaB_bind PF10410.9 KXG48619.1 - 0.12 12.6 1.8 0.39 10.9 0.3 2.5 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase Gln-synt_C PF00120.24 KXG48620.1 - 2.6e-77 260.1 0.0 3.2e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Cation_efflux PF01545.21 KXG48621.1 - 1.3e-13 51.1 9.4 1.8e-13 50.6 9.4 1.1 1 0 0 1 1 1 1 Cation efflux family Cutinase PF01083.22 KXG48623.1 - 1e-48 165.6 1.2 1.2e-48 165.4 1.2 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KXG48623.1 - 0.00031 20.7 0.0 0.00049 20.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 KXG48623.1 - 0.00097 18.8 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain FBP_C PF16571.5 KXG48623.1 - 0.05 13.1 0.1 0.094 12.2 0.1 1.4 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger DUF2974 PF11187.8 KXG48623.1 - 0.059 12.9 0.1 0.078 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 KXG48623.1 - 0.089 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Cyclase PF04199.13 KXG48624.1 - 3.8e-09 36.9 0.0 5.2e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase DUF5490 PF17593.2 KXG48624.1 - 0.039 14.0 0.1 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5490) RHD3 PF05879.12 KXG48625.1 - 0 1062.2 0.0 0 1061.9 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KXG48625.1 - 7.1e-07 28.7 0.1 1.2e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KXG48625.1 - 7.8e-06 26.1 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KXG48625.1 - 0.00066 19.7 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KXG48625.1 - 0.0016 18.7 0.5 0.0043 17.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Phi_1 PF04674.12 KXG48625.1 - 0.12 11.6 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region Lipase_GDSL_2 PF13472.6 KXG48626.1 - 9.1e-07 29.4 0.7 2.7e-06 27.9 0.7 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXG48626.1 - 6.5e-06 26.3 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Fungal_trans PF04082.18 KXG48626.1 - 0.00026 20.1 0.2 0.00072 18.7 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain GTP_EFTU PF00009.27 KXG48627.1 - 1.7e-57 194.1 0.2 2.4e-57 193.6 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXG48627.1 - 3.4e-20 72.4 0.0 6.2e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXG48627.1 - 1.6e-17 63.6 1.7 1.6e-17 63.6 1.7 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXG48627.1 - 8.4e-06 25.8 0.1 1.8e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXG48627.1 - 0.0015 18.4 0.3 0.0071 16.3 0.1 2.0 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 KXG48627.1 - 0.022 14.4 0.2 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KXG48627.1 - 0.04 13.7 0.1 6.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IF3_N PF05198.16 KXG48628.1 - 4.9e-11 42.7 0.0 8.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 KXG48628.1 - 6.6e-09 35.6 0.3 1.3e-08 34.7 0.3 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 KXG48628.1 - 3.9e-05 23.4 1.5 7.1e-05 22.5 1.4 1.4 1 1 0 1 1 1 1 Mitochondrial translation initiation factor Extensin_1 PF02095.15 KXG48628.1 - 8.4 6.9 7.9 0.83 10.0 2.7 2.1 2 0 0 2 2 2 0 Extensin-like protein repeat GDA1_CD39 PF01150.17 KXG48629.1 - 1.1e-100 337.4 0.0 1.4e-100 336.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4598 PF15370.6 KXG48630.1 - 2.6e-32 111.6 5.2 2.6e-32 111.6 5.2 4.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4598) COMPASS-Shg1 PF05205.12 KXG48630.1 - 1.2e-26 93.3 0.0 1.2e-26 93.3 0.0 2.4 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF4692 PF15763.5 KXG48630.1 - 0.2 12.1 0.1 0.2 12.1 0.1 3.6 2 1 1 3 3 3 0 Regulator of human erythroid cell expansion (RHEX) zf-rbx1 PF12678.7 KXG48632.1 - 5.1e-09 36.3 1.4 1.3e-08 35.0 1.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXG48632.1 - 5.4e-08 33.0 6.7 1.4e-07 31.7 2.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KXG48632.1 - 1.2e-06 28.3 0.8 2e-06 27.5 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXG48632.1 - 4e-06 26.7 1.0 1.1e-05 25.3 1.0 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXG48632.1 - 6.6e-06 25.9 2.1 6.6e-06 25.9 2.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXG48632.1 - 0.00017 21.2 1.2 0.00085 18.9 0.6 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KXG48632.1 - 0.00038 20.3 1.3 0.00038 20.3 1.3 1.8 3 0 0 3 3 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KXG48632.1 - 0.00053 19.8 1.2 0.00053 19.8 1.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXG48632.1 - 0.0022 18.0 1.9 0.0022 18.0 1.9 3.5 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_11 PF17123.5 KXG48632.1 - 0.0023 17.6 11.8 0.012 15.3 0.3 3.6 4 0 0 4 4 4 2 RING-like zinc finger zf-ANAPC11 PF12861.7 KXG48632.1 - 0.0099 15.9 1.1 0.022 14.8 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.8 KXG48632.1 - 0.06 11.2 0.6 0.091 10.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) Oxidored_q2 PF00420.24 KXG48632.1 - 0.16 11.6 2.4 0.37 10.4 2.4 1.6 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PQ-loop PF04193.14 KXG48632.1 - 1.4 8.7 10.3 0.26 11.1 0.4 3.0 3 0 0 3 3 2 0 PQ loop repeat zf-C3H2C3 PF17122.5 KXG48632.1 - 1.5 8.9 3.4 2.3 8.4 1.6 2.3 2 0 0 2 2 2 0 Zinc-finger RINGv PF12906.7 KXG48632.1 - 3.5 7.8 5.8 0.55 10.4 1.6 1.8 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.8 KXG48632.1 - 6.8 7.0 6.5 36 4.6 6.5 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain GCV_H PF01597.19 KXG48633.1 - 4.8e-36 123.3 2.4 5.8e-36 123.1 2.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 KXG48633.1 - 0.087 12.7 1.4 0.78 9.6 0.4 2.2 1 1 1 2 2 2 0 Biotin-requiring enzyme Ribosomal_S6 PF01250.17 KXG48634.1 - 1.1e-21 76.9 0.0 1.4e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 4HBT_3 PF13622.6 KXG48635.1 - 2.6e-30 106.5 0.9 4.8e-30 105.6 0.9 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily PIG-Y PF15159.6 KXG48636.1 - 1.4e-22 80.4 8.6 2e-22 79.8 8.6 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 KXG48636.1 - 0.036 14.6 1.9 5.2 7.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF2956 PF11169.8 KXG48636.1 - 5.8 7.2 6.0 1.9 8.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) RRM_1 PF00076.22 KXG48637.1 - 1.3e-61 204.4 0.0 6.8e-21 73.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXG48637.1 - 6.1e-11 42.0 0.0 0.00098 18.9 0.0 3.9 3 2 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KXG48637.1 - 1.2e-08 34.6 0.0 0.00058 19.5 0.0 3.4 2 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXG48637.1 - 0.0001 22.3 0.1 0.34 11.1 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KXG48637.1 - 0.00053 19.9 0.0 0.42 10.7 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 KXG48637.1 - 0.0014 18.6 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) SET_assoc PF11767.8 KXG48637.1 - 0.0018 17.9 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 2 Histone lysine methyltransferase SET associated RRM_8 PF11835.8 KXG48637.1 - 0.0074 16.5 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 1 RRM-like domain Arrestin_C PF02752.22 KXG48639.1 - 4.6e-20 72.4 0.0 2e-19 70.4 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KXG48639.1 - 7.4e-08 32.6 0.0 0.001 19.2 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KXG48639.1 - 0.0087 15.8 0.0 0.19 11.4 0.0 2.4 2 0 0 2 2 2 1 Arrestin_N terminal like Acetyltransf_10 PF13673.7 KXG48640.1 - 2.8e-11 43.4 0.0 5e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG48640.1 - 1.1e-09 38.5 0.0 2e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXG48640.1 - 1.4e-08 35.1 0.0 2.2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXG48640.1 - 8.1e-05 22.7 0.2 0.28 11.3 0.0 3.0 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG48640.1 - 0.0025 17.8 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXG48640.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase APH PF01636.23 KXG48641.1 - 6.1e-08 32.9 0.1 9.4e-07 29.0 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG48641.1 - 0.094 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Chs7 PF12271.8 KXG48642.1 - 1.9e-115 385.2 14.4 2.2e-115 385.0 14.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 KXG48642.1 - 0.018 15.3 3.9 0.018 15.3 3.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) Abhydrolase_6 PF12697.7 KXG48643.1 - 2e-05 25.3 1.4 2.9e-05 24.8 1.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KXG48643.1 - 3.1e-05 23.6 0.0 5.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KXG48643.1 - 0.001 18.8 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KXG48643.1 - 0.0026 17.1 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 KXG48643.1 - 0.042 13.0 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase EII-GUT PF03608.13 KXG48643.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 PTS system enzyme II sorbitol-specific factor DUF900 PF05990.12 KXG48643.1 - 0.17 11.3 0.1 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) GATase_4 PF13230.6 KXG48644.1 - 3.9e-11 42.4 0.0 6.6e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KXG48644.1 - 8.2e-08 32.5 0.0 1.4e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Dynamin_N PF00350.23 KXG48645.1 - 4e-45 153.9 0.0 7.2e-45 153.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KXG48645.1 - 4.6e-14 52.3 0.0 2.6e-11 43.3 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KXG48645.1 - 5.5e-06 26.5 0.1 0.00035 20.6 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KXG48645.1 - 0.0073 16.1 0.3 0.24 11.1 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 KXG48645.1 - 0.022 15.1 1.0 0.25 11.7 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain Se-cys_synth_N PF12390.8 KXG48645.1 - 0.048 13.9 0.0 0.19 11.9 0.0 2.1 1 0 0 1 1 1 0 Selenocysteine synthase N terminal AAA_21 PF13304.6 KXG48645.1 - 0.072 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Pyr_redox_2 PF07992.14 KXG48646.1 - 2.9e-52 177.7 0.0 3.7e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG48646.1 - 5.2e-11 43.0 0.0 1.8e-09 38.0 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG48646.1 - 0.00048 19.5 0.0 0.3 10.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Cyclin PF08613.11 KXG48647.1 - 5.7e-16 59.3 0.1 1.6e-15 57.8 0.1 1.7 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KXG48647.1 - 0.00064 19.5 0.0 0.00097 18.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L27A PF00828.19 KXG48648.1 - 1.2e-28 100.4 0.4 1.6e-28 99.9 0.4 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pkinase PF00069.25 KXG48649.1 - 4.8e-46 157.3 0.0 6.2e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48649.1 - 4.1e-25 88.5 0.0 3.1e-20 72.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXG48649.1 - 0.046 12.5 0.0 0.1 11.4 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase SH3_1 PF00018.28 KXG48650.1 - 1.5e-06 27.7 0.0 3.1e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXG48650.1 - 0.0023 17.7 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_16 PF18348.1 KXG48650.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain PQ-loop PF04193.14 KXG48652.1 - 1.2e-37 127.5 12.4 4.5e-19 68.0 0.5 2.4 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 KXG48652.1 - 0.045 13.8 5.6 0.2 11.7 0.0 2.6 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF4648 PF15505.6 KXG48652.1 - 0.14 13.1 0.1 0.3 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) Cyclin PF08613.11 KXG48653.1 - 6.4e-13 49.4 0.0 9.6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXG48653.1 - 7.8e-05 22.4 0.3 0.00015 21.5 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain TT_ORF2 PF02957.15 KXG48653.1 - 1.2 10.1 8.1 0.12 13.3 1.2 2.6 3 0 0 3 3 3 0 TT viral ORF2 His_Phos_1 PF00300.22 KXG48654.1 - 4.7e-30 104.7 0.0 1.1e-29 103.5 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) P5-ATPase PF12409.8 KXG48654.1 - 0.24 11.5 0.0 0.24 11.5 0.0 2.4 3 0 0 3 3 3 0 P5-type ATPase cation transporter Dor1 PF04124.12 KXG48655.1 - 1.3e-56 191.8 3.4 8.1e-46 156.2 2.8 2.4 2 0 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 KXG48655.1 - 0.00013 22.0 0.7 0.00043 20.3 0.7 2.0 1 0 0 1 1 1 1 Vps51/Vps67 PhoD PF09423.10 KXG48656.1 - 2.8e-113 378.5 0.7 3.6e-113 378.2 0.7 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KXG48656.1 - 5.2e-35 119.9 0.0 1.1e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Acetyltransf_3 PF13302.7 KXG48656.1 - 9.3e-08 32.8 0.0 3.3e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Pur_ac_phosph_N PF16656.5 KXG48656.1 - 1.6e-05 25.4 0.5 3.9e-05 24.1 0.5 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Transferase PF02458.15 KXG48657.1 - 1.6e-14 53.4 0.0 3.1e-14 52.5 0.0 1.4 1 1 0 1 1 1 1 Transferase family PhyH PF05721.13 KXG48658.1 - 1.2e-21 77.9 0.0 2.2e-21 77.1 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KXG48658.1 - 6.5e-07 28.5 0.4 3.5e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1479) FAD_binding_4 PF01565.23 KXG48659.1 - 1.8e-17 63.4 3.3 3e-17 62.6 3.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG48659.1 - 1.6e-08 34.5 0.1 1.6e-08 34.5 0.1 1.9 2 0 0 2 2 2 1 Berberine and berberine like Pyridoxal_deC PF00282.19 KXG48660.1 - 2.3e-67 227.3 0.0 3.2e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KXG48660.1 - 9.9e-08 31.6 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KXG48660.1 - 3.5e-07 29.5 0.0 4.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXG48660.1 - 1.7e-05 24.2 0.0 5.3e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II SepSecS PF05889.13 KXG48660.1 - 0.07 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DegT_DnrJ_EryC1 PF01041.17 KXG48660.1 - 0.17 11.2 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family p450 PF00067.22 KXG48661.1 - 2.9e-32 112.0 0.0 4.1e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Catalase PF00199.19 KXG48662.1 - 9.6e-129 429.8 0.0 1.2e-128 429.5 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KXG48662.1 - 3.5e-06 27.1 0.3 8.5e-06 25.9 0.1 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive Methyltransf_11 PF08241.12 KXG48663.1 - 1.7e-20 73.5 0.0 2.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG48663.1 - 9.2e-20 71.2 0.0 1.6e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG48663.1 - 6.3e-19 68.3 0.0 7.6e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG48663.1 - 5.9e-17 62.0 0.0 9.4e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXG48663.1 - 4.1e-16 59.1 0.0 5.8e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KXG48663.1 - 4.5e-12 45.8 0.0 1e-11 44.7 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXG48663.1 - 1.2e-11 45.2 0.0 2.4e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KXG48663.1 - 1.7e-05 23.9 0.0 2.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 KXG48663.1 - 4.9e-05 23.2 0.0 7.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 KXG48663.1 - 0.00014 21.5 0.1 0.00022 20.8 0.1 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 NodS PF05401.11 KXG48663.1 - 0.00081 19.1 0.0 0.0016 18.1 0.0 1.4 2 0 0 2 2 2 1 Nodulation protein S (NodS) MTS PF05175.14 KXG48663.1 - 0.00099 18.7 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KXG48663.1 - 0.001 18.7 0.1 0.0051 16.4 0.1 1.9 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 KXG48663.1 - 0.0019 17.7 0.0 0.0094 15.4 0.0 2.1 2 1 1 3 3 3 1 Putative methyltransferase Methyltransf_8 PF05148.15 KXG48663.1 - 0.017 15.0 0.1 1.4 8.7 0.0 2.7 2 1 0 2 2 2 0 Hypothetical methyltransferase DREV PF05219.12 KXG48663.1 - 0.03 13.4 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase ADH_zinc_N PF00107.26 KXG48663.1 - 0.08 12.9 0.0 0.16 11.9 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_32 PF13679.6 KXG48663.1 - 0.14 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Trp_DMAT PF11991.8 KXG48664.1 - 4.7e-107 358.5 0.1 5.7e-107 358.3 0.1 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase TNT PF14021.6 KXG48665.1 - 7.1e-32 109.8 0.0 1.1e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Tuberculosis necrotizing toxin Phosphoesterase PF04185.14 KXG48666.1 - 1.6e-58 198.6 3.6 3e-58 197.7 3.6 1.4 1 1 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.19 KXG48667.1 - 3.8e-62 210.0 2.2 4.5e-62 209.7 2.2 1.1 1 0 0 1 1 1 1 VIT family Abhydrolase_9_N PF15420.6 KXG48667.1 - 0.031 14.3 0.9 0.057 13.4 0.9 1.4 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus SLATT_fungal PF18142.1 KXG48667.1 - 0.13 12.3 1.0 0.18 11.8 0.1 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain PAP2_3 PF14378.6 KXG48668.1 - 1.3e-24 86.9 13.0 1.8e-24 86.5 13.0 1.1 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 KXG48668.1 - 9.6e-12 44.8 2.2 1.8e-11 43.9 2.2 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KXG48668.1 - 0.12 12.9 4.3 0.38 11.3 4.3 1.8 1 0 0 1 1 1 0 PAP2 superfamily C-terminal LCAT PF02450.15 KXG48669.1 - 8.7e-107 357.7 0.0 1.1e-106 357.4 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 KXG48669.1 - 0.032 13.8 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) BAAT_C PF08840.11 KXG48669.1 - 0.042 13.8 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF900 PF05990.12 KXG48669.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Acetyltransf_1 PF00583.25 KXG48670.1 - 1.6e-19 70.2 0.0 2.4e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXG48670.1 - 9.9e-13 48.1 0.0 1.4e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXG48670.1 - 7.9e-12 45.4 0.0 1.4e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG48670.1 - 8.8e-11 41.6 0.0 1.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KXG48670.1 - 1.6e-08 35.3 0.0 2.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXG48670.1 - 2.3e-06 27.4 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXG48670.1 - 6.4e-06 26.3 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXG48670.1 - 0.00022 21.3 0.0 0.0004 20.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KXG48670.1 - 0.0045 17.1 0.0 0.0059 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KXG48670.1 - 0.05 13.2 0.0 0.065 12.8 0.0 1.3 1 1 0 1 1 1 0 GNAT acetyltransferase PanZ PF12568.8 KXG48670.1 - 0.053 13.2 0.1 0.081 12.7 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_15 PF17013.5 KXG48670.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 KXG48670.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PPR_2 PF13041.6 KXG48671.1 - 0.014 15.6 0.0 0.74 10.1 0.0 3.3 3 0 0 3 3 3 0 PPR repeat family Pex24p PF06398.11 KXG48672.1 - 2.5e-07 30.0 6.4 4.4e-07 29.2 6.4 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Mis14 PF08641.12 KXG48673.1 - 6.3e-28 97.7 4.7 6.3e-28 97.7 4.7 1.7 2 0 0 2 2 2 1 Kinetochore protein Mis14 like PBP_sp32 PF07222.12 KXG48673.1 - 0.11 11.9 1.8 0.18 11.3 1.8 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Rep_4 PF05797.11 KXG48673.1 - 0.93 8.6 3.3 1.3 8.0 3.3 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) DUF4637 PF15470.6 KXG48673.1 - 1.3 8.7 5.1 2.2 8.0 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pox_Ag35 PF03286.14 KXG48673.1 - 2.4 7.9 8.7 3.9 7.2 8.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SAPS PF04499.15 KXG48673.1 - 4.5 5.9 8.7 5.8 5.6 8.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CRAL_TRIO PF00650.20 KXG48674.1 - 3.3e-36 124.4 0.0 4.6e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXG48674.1 - 4.4e-09 36.4 0.6 1.1e-08 35.1 0.6 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXG48674.1 - 0.00065 19.9 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TMF_DNA_bd PF12329.8 KXG48674.1 - 0.055 13.5 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Glyco_transf_24 PF18404.1 KXG48674.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Glucosyltransferase 24 RasGAP PF00616.19 KXG48675.1 - 2.7e-59 200.4 0.3 5.3e-59 199.4 0.0 1.6 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KXG48675.1 - 5.1e-31 107.6 0.5 5.1e-31 107.6 0.5 2.2 2 0 0 2 2 2 1 RasGAP C-terminus MarR PF01047.22 KXG48675.1 - 0.11 12.5 0.2 0.57 10.2 0.1 2.3 2 0 0 2 2 2 0 MarR family CD36 PF01130.21 KXG48675.1 - 0.11 11.1 0.1 0.18 10.3 0.1 1.3 1 0 0 1 1 1 0 CD36 family DNA_pol_A_exo1 PF01612.20 KXG48676.1 - 1.9e-40 138.4 0.1 3e-40 137.8 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KXG48676.1 - 9.1e-29 100.0 0.7 3.2e-28 98.3 0.3 2.2 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 KXG48676.1 - 1.7e-10 40.8 0.0 3.5e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 HRDC domain UPF0203 PF05254.12 KXG48677.1 - 8.8e-27 93.2 0.8 1e-26 93.0 0.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KXG48677.1 - 0.00022 21.5 0.5 0.00045 20.5 0.5 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KXG48677.1 - 0.0019 18.2 1.5 0.018 15.1 0.4 2.1 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 KXG48677.1 - 0.0049 17.0 1.6 0.2 11.9 1.6 2.0 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein DUF5339 PF17274.2 KXG48677.1 - 0.46 11.4 3.2 2.4 9.1 0.2 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5339) Gpi1 PF05024.15 KXG48678.1 - 3.7e-78 261.9 8.5 7.1e-78 261.0 8.5 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) MutS_V PF00488.21 KXG48679.1 - 6.4e-81 270.9 0.1 1.2e-80 270.1 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXG48679.1 - 2.3e-38 132.3 0.5 5.9e-38 131.0 0.5 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 KXG48679.1 - 1.4e-18 67.5 0.2 4.7e-18 65.8 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KXG48679.1 - 5.2e-17 62.0 2.3 7.3e-17 61.5 1.0 2.0 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.20 KXG48679.1 - 2.1e-15 57.0 0.0 1.7e-14 54.0 0.0 2.3 2 0 0 2 2 2 1 MutS domain I Vip3A_N PF12495.8 KXG48679.1 - 0.041 13.8 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal SUR7 PF06687.12 KXG48679.1 - 0.086 12.5 0.0 0.42 10.2 0.0 2.1 2 1 0 2 2 2 0 SUR7/PalI family CDT1_C PF16679.5 KXG48680.1 - 8.5e-21 74.2 0.0 1.3e-19 70.4 0.0 2.3 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain Spc7_N PF15402.6 KXG48680.1 - 4.7 5.3 9.6 7.9 4.6 9.6 1.4 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Apolipoprotein PF01442.18 KXG48681.1 - 0.0038 17.1 4.0 0.0081 16.1 4.0 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain LUC7 PF03194.15 KXG48681.1 - 0.016 14.9 3.4 0.019 14.6 3.4 1.0 1 0 0 1 1 1 0 LUC7 N_terminus DUF883 PF05957.13 KXG48681.1 - 0.027 15.1 8.0 0.11 13.1 2.7 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ApoO PF09769.9 KXG48681.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Apolipoprotein O ZnuA PF01297.17 KXG48681.1 - 0.14 11.6 1.7 0.15 11.5 1.7 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Atg14 PF10186.9 KXG48681.1 - 0.14 11.2 0.5 0.16 11.0 0.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3584 PF12128.8 KXG48681.1 - 0.18 9.3 5.3 0.22 9.0 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) THOC7 PF05615.13 KXG48681.1 - 0.18 12.1 4.7 0.25 11.6 4.7 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 SNARE PF05739.19 KXG48681.1 - 0.37 10.8 3.9 1.1 9.3 0.8 2.3 2 0 0 2 2 2 0 SNARE domain OmpH PF03938.14 KXG48681.1 - 0.51 10.7 6.6 0.68 10.3 6.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-C2H2 PF00096.26 KXG48682.1 - 5.7e-06 26.5 15.4 0.0056 17.1 2.3 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXG48682.1 - 0.00026 21.3 3.8 0.00026 21.3 3.8 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXG48682.1 - 0.0079 16.9 15.4 0.07 14.0 2.9 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger TylF PF05711.11 KXG48682.1 - 0.082 12.2 0.0 0.33 10.2 0.0 1.8 2 0 0 2 2 2 0 Macrocin-O-methyltransferase (TylF) zf-H2C2_5 PF13909.6 KXG48682.1 - 1.3 8.8 5.6 2.3 8.0 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Glyco_hydro_72 PF03198.14 KXG48683.1 - 2.1e-136 454.3 5.8 2.6e-136 454.0 5.8 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KXG48683.1 - 1.1e-06 28.3 0.2 6.4e-06 25.8 0.2 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KXG48683.1 - 0.001 18.2 1.1 0.0033 16.6 1.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain COG5 PF10392.9 KXG48684.1 - 2.4e-39 134.5 1.0 2.4e-39 134.5 1.0 2.3 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Aldolase_II PF00596.21 KXG48685.1 - 1.8e-47 161.7 0.2 2.5e-47 161.3 0.2 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SYS1 PF09801.9 KXG48686.1 - 4e-54 182.7 7.5 4.7e-54 182.5 7.5 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF3792 PF12670.7 KXG48686.1 - 0.51 10.5 0.1 0.51 10.5 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) DUF4199 PF13858.6 KXG48686.1 - 3.6 8.0 8.0 4.8 7.6 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) COX6B PF02297.17 KXG48687.1 - 2.3e-23 82.2 3.3 3.1e-23 81.8 3.3 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 KXG48687.1 - 0.032 14.5 1.4 0.072 13.4 1.4 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 RRM_1 PF00076.22 KXG48688.1 - 9e-06 25.4 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXG48688.1 - 0.18 11.4 0.0 0.44 10.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U3_assoc_6 PF08640.11 KXG48689.1 - 4.5e-29 100.3 0.8 4.5e-29 100.3 0.8 1.9 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KXG48689.1 - 9.1e-06 26.1 1.0 0.034 15.0 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat Suf PF05843.14 KXG48689.1 - 3.5e-05 23.9 0.6 0.12 12.3 0.0 2.6 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 KXG48689.1 - 0.015 14.5 0.1 0.023 13.8 0.1 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Frag1 PF10277.9 KXG48690.1 - 1.1e-42 146.1 8.8 1.1e-42 146.1 8.8 2.9 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family DUF4271 PF14093.6 KXG48690.1 - 1.9 8.4 11.0 0.28 11.1 0.6 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4271) Metal_resist PF13801.6 KXG48691.1 - 6.5 7.0 16.4 0.44 10.7 6.8 2.4 2 0 0 2 2 2 0 Heavy-metal resistance Lactamase_B_6 PF16661.5 KXG48692.1 - 1.6e-65 220.1 0.0 3.8e-65 219.0 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KXG48692.1 - 1.5e-47 162.0 0.1 3.5e-47 160.8 0.1 1.7 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KXG48692.1 - 1.4e-15 57.5 0.0 8.9e-15 54.9 0.0 2.3 2 1 0 3 3 3 1 Beta-Casp domain RMMBL PF07521.12 KXG48692.1 - 6.5e-12 45.2 0.0 1.7e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KXG48692.1 - 0.016 15.2 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily AA_permease_2 PF13520.6 KXG48693.1 - 1.1e-59 202.4 43.5 1.1e-59 202.4 43.5 1.2 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG48693.1 - 1.8e-19 69.7 38.8 2.3e-19 69.4 38.8 1.1 1 0 0 1 1 1 1 Amino acid permease Sec23_trunk PF04811.15 KXG48694.1 - 2.3e-55 187.8 0.0 5.3e-55 186.6 0.0 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KXG48694.1 - 8.8e-26 89.7 0.0 2e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KXG48694.1 - 1.8e-17 63.8 0.0 3.6e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KXG48694.1 - 8.5e-16 57.7 5.2 1.7e-15 56.7 5.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXG48694.1 - 9e-08 31.9 0.0 2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat DUF1678 PF07913.11 KXG48694.1 - 0.12 12.1 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) SLS PF14611.6 KXG48694.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator ABC_tran PF00005.27 KXG48696.1 - 7.1e-51 172.3 0.0 7.1e-25 88.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 KXG48696.1 - 8.2e-50 169.1 32.3 1.1e-30 106.6 9.9 2.3 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 KXG48696.1 - 2e-11 44.3 7.6 0.0019 18.1 0.1 4.7 5 0 0 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXG48696.1 - 1.2e-09 38.8 0.1 0.0011 19.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXG48696.1 - 1.5e-09 38.0 0.2 0.0022 17.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KXG48696.1 - 9.9e-08 32.7 0.1 0.0018 18.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KXG48696.1 - 2.2e-07 30.5 4.5 0.00047 19.7 0.3 4.1 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXG48696.1 - 2.5e-06 27.1 4.2 0.039 13.7 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KXG48696.1 - 3e-06 27.0 0.0 0.1 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KXG48696.1 - 9.5e-06 25.9 0.1 0.2 11.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 KXG48696.1 - 5.7e-05 23.1 0.1 0.072 13.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 KXG48696.1 - 9.6e-05 22.8 0.0 0.53 10.7 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KXG48696.1 - 0.0001 22.3 3.0 0.021 14.9 0.2 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 KXG48696.1 - 0.00014 21.1 0.1 0.01 14.9 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_28 PF13521.6 KXG48696.1 - 0.00015 22.0 0.2 1.1 9.5 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 KXG48696.1 - 0.00017 21.6 0.1 0.13 12.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KXG48696.1 - 0.00041 20.7 0.0 0.59 10.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 KXG48696.1 - 0.00044 20.2 0.0 0.096 12.6 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea cobW PF02492.19 KXG48696.1 - 0.00045 19.8 0.8 0.36 10.4 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KXG48696.1 - 0.00098 19.3 0.1 0.55 10.5 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DnaB_C PF03796.15 KXG48696.1 - 0.0011 18.3 0.1 0.54 9.5 0.0 2.3 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_18 PF13238.6 KXG48696.1 - 0.0012 19.3 0.0 0.57 10.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXG48696.1 - 0.0013 18.9 0.0 0.81 9.8 0.0 3.1 4 0 0 4 4 2 1 AAA domain AAA_15 PF13175.6 KXG48696.1 - 0.0014 18.5 0.0 2.5 7.7 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 KXG48696.1 - 0.0016 18.2 0.6 0.5 10.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KXG48696.1 - 0.0024 17.6 0.1 1.8 8.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KXG48696.1 - 0.0037 17.0 0.1 0.72 9.6 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain SRPRB PF09439.10 KXG48696.1 - 0.0039 16.6 0.4 2.2 7.7 0.1 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit KAP_NTPase PF07693.14 KXG48696.1 - 0.0053 16.0 0.0 2.5 7.3 0.0 2.2 2 0 0 2 2 2 1 KAP family P-loop domain Cytidylate_kin PF02224.18 KXG48696.1 - 0.01 15.6 0.7 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase PRK PF00485.18 KXG48696.1 - 0.019 14.7 0.3 3.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_11 PF13086.6 KXG48696.1 - 0.02 14.7 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KXG48696.1 - 0.02 15.2 0.1 11 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXG48696.1 - 0.022 14.1 0.1 2.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KXG48696.1 - 0.029 13.7 0.1 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 KXG48696.1 - 0.04 13.7 0.2 9.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF2627 PF11118.8 KXG48696.1 - 0.048 14.2 3.3 8.4 7.1 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) AAA_7 PF12775.7 KXG48696.1 - 0.048 13.2 0.2 9.3 5.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KXG48696.1 - 0.057 13.2 0.2 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 KXG48696.1 - 0.061 12.8 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF4388 PF14332.6 KXG48696.1 - 0.072 13.4 0.1 1.9 8.8 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4388) ATP-synt_ab PF00006.25 KXG48696.1 - 0.083 12.5 0.1 9.2 5.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.17 KXG48696.1 - 0.086 12.9 1.2 4.7 7.2 1.2 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain TsaE PF02367.17 KXG48696.1 - 0.091 12.8 0.2 16 5.5 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 KXG48696.1 - 0.098 12.6 0.3 17 5.3 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KXG48696.1 - 0.12 12.3 0.1 7.8 6.4 0.0 2.6 3 0 0 3 3 2 0 NTPase DUF2075 PF09848.9 KXG48696.1 - 0.15 11.3 0.1 6.9 5.8 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KXG48696.1 - 0.19 10.9 0.1 4.4 6.4 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_35 PF14516.6 KXG48696.1 - 0.2 10.5 0.2 5.9 5.6 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain SRP54 PF00448.22 KXG48696.1 - 0.22 11.1 0.3 19 4.8 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Pox_A32 PF04665.12 KXG48696.1 - 0.27 10.7 1.1 15 5.0 0.3 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Septin PF00735.18 KXG48696.1 - 0.28 10.4 0.2 21 4.3 0.0 2.3 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.23 KXG48696.1 - 0.4 10.7 4.5 5.6 7.0 0.5 2.5 2 0 0 2 2 2 0 Dynamin family Fungal_trans_2 PF11951.8 KXG48697.1 - 4.3e-64 216.7 0.2 5.3e-64 216.4 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG48697.1 - 7.6e-10 38.8 10.8 1.2e-09 38.2 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2385 PF09539.10 KXG48697.1 - 0.056 14.0 0.0 22 5.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) AT_hook PF02178.19 KXG48697.1 - 0.44 10.6 6.8 1.1 9.3 6.8 1.8 1 0 0 1 1 1 0 AT hook motif Gti1_Pac2 PF09729.9 KXG48698.1 - 3.4e-44 151.1 5.4 2.1e-37 129.0 0.1 2.8 2 1 1 3 3 3 2 Gti1/Pac2 family tRNA-synt_2 PF00152.20 KXG48699.1 - 1.7e-66 224.5 0.0 6.5e-66 222.5 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXG48699.1 - 1.6e-06 28.0 0.0 3.1e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RRM_1 PF00076.22 KXG48700.1 - 3.3e-12 46.0 0.0 6.4e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tmemb_cc2 PF10267.9 KXG48700.1 - 0.0034 16.6 0.1 0.0034 16.6 0.1 2.3 4 0 0 4 4 4 1 Predicted transmembrane and coiled-coil 2 protein Gp-FAR-1 PF05823.12 KXG48700.1 - 0.015 15.6 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FAM184 PF15665.5 KXG48700.1 - 0.048 13.4 0.2 0.048 13.4 0.2 1.8 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B MOZ_SAS PF01853.18 KXG48701.1 - 3.2e-61 206.1 0.0 4.9e-61 205.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KXG48701.1 - 9.1e-18 63.6 0.2 1.5e-17 62.9 0.2 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Cpn60_TCP1 PF00118.24 KXG48702.1 - 2.3e-163 544.4 0.2 2.5e-163 544.2 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nop PF01798.18 KXG48703.1 - 3.6e-88 294.9 0.1 3.6e-88 294.9 0.1 1.6 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KXG48703.1 - 5.1e-19 68.4 0.1 5.1e-19 68.4 0.1 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain YL1 PF05764.13 KXG48703.1 - 0.27 11.3 21.9 0.41 10.7 21.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein RNA_polI_A34 PF08208.11 KXG48703.1 - 5.1 7.1 28.6 9.4 6.3 28.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3767 PF12597.8 KXG48705.1 - 1.7e-31 108.0 0.0 2.5e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF4381 PF14316.6 KXG48705.1 - 0.13 12.6 1.8 0.3 11.3 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF1744 PF08490.12 KXG48706.1 - 1.3e-148 494.8 0.0 1.9e-148 494.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KXG48706.1 - 3.2e-85 286.3 1.3 1.2e-84 284.3 1.2 2.0 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain Pkinase PF00069.25 KXG48706.1 - 1.1e-72 244.6 0.0 1.8e-72 243.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48706.1 - 2.6e-29 102.3 0.0 4.4e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DNA_pol_B PF00136.21 KXG48706.1 - 8e-15 54.5 0.1 4.4e-11 42.2 0.0 3.6 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KXG48706.1 - 4.9e-08 32.9 0.0 2.7e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Kinase-like PF14531.6 KXG48706.1 - 3e-06 26.8 0.0 5.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RNase_H_2 PF13482.6 KXG48706.1 - 9.3e-05 22.5 0.0 0.00036 20.5 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily Kdo PF06293.14 KXG48706.1 - 0.00027 20.4 0.1 0.003 16.9 0.0 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXG48706.1 - 0.00049 19.0 0.0 0.0009 18.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXG48706.1 - 0.0036 17.2 0.1 0.0081 16.1 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-MIZ PF02891.20 KXG48706.1 - 0.2 11.4 2.9 5.2 6.9 0.6 2.8 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-CHY PF05495.12 KXG48706.1 - 0.5 10.9 2.3 1.6 9.2 2.3 1.9 1 0 0 1 1 1 0 CHY zinc finger AMMECR1 PF01871.17 KXG48707.1 - 1.7e-40 138.3 0.0 4.9e-40 136.9 0.0 1.7 2 0 0 2 2 2 1 AMMECR1 Apt1 PF10351.9 KXG48707.1 - 0.00016 20.7 3.9 0.00016 20.7 3.9 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain DUF4129 PF13559.6 KXG48707.1 - 0.033 14.4 1.6 0.16 12.2 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4129) SMN PF06003.12 KXG48707.1 - 0.063 12.5 5.7 0.099 11.9 5.7 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) TRAP_alpha PF03896.16 KXG48707.1 - 0.31 10.2 4.4 0.48 9.6 4.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ndc1_Nup PF09531.10 KXG48707.1 - 0.47 9.1 6.9 0.55 8.9 6.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CytochromB561_N PF09786.9 KXG48707.1 - 0.55 9.2 11.3 0.72 8.8 11.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Macoilin PF09726.9 KXG48707.1 - 0.64 8.5 11.0 0.84 8.1 11.0 1.1 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 KXG48707.1 - 1.5 6.5 10.7 2 6.1 10.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4551 PF15087.6 KXG48707.1 - 2 7.2 11.4 2.5 6.8 11.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Presenilin PF01080.17 KXG48707.1 - 2.9 6.6 9.9 3.8 6.2 9.9 1.1 1 0 0 1 1 1 0 Presenilin YebO PF13974.6 KXG48707.1 - 3.6 7.7 6.1 7.5 6.7 6.1 1.5 1 0 0 1 1 1 0 YebO-like protein SPX PF03105.19 KXG48707.1 - 5.9 6.7 17.5 8 6.3 17.5 1.1 1 0 0 1 1 1 0 SPX domain CDC45 PF02724.14 KXG48707.1 - 6.4 4.9 11.0 8.3 4.6 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein HNH_2 PF13391.6 KXG48708.1 - 1.2e-12 47.8 0.0 2.1e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease SHMT PF00464.19 KXG48709.1 - 9.9e-208 689.6 0.0 1.1e-207 689.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KXG48709.1 - 7.6e-07 28.6 0.0 1.8e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXG48709.1 - 0.0021 17.1 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXG48709.1 - 0.0099 15.2 0.0 0.018 14.3 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KXG48709.1 - 0.058 11.9 0.0 0.1 11.1 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Med9 PF07544.13 KXG48710.1 - 6.5e-17 61.4 0.0 1.6e-16 60.1 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DUF2730 PF10805.8 KXG48710.1 - 0.02 14.9 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Med21 PF11221.8 KXG48710.1 - 0.043 14.1 2.5 0.087 13.1 2.5 1.7 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Spc29 PF17082.5 KXG48710.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 iPGM_N PF06415.13 KXG48711.1 - 7.5e-76 254.3 0.0 1.1e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KXG48711.1 - 1.2e-69 234.5 0.0 1.3e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 KXG48711.1 - 7.2e-07 29.1 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXG48711.1 - 9.7e-05 21.9 0.0 0.00017 21.1 0.0 1.6 1 1 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.20 KXG48711.1 - 0.069 12.1 0.0 0.2 10.6 0.0 1.6 2 0 0 2 2 2 0 Alkaline phosphatase Prefoldin_2 PF01920.20 KXG48712.1 - 1.6e-23 82.7 11.9 1.9e-23 82.4 11.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Spc24 PF08286.11 KXG48712.1 - 2.2e-05 24.6 11.2 0.0019 18.4 2.0 2.1 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 Prefoldin_3 PF13758.6 KXG48712.1 - 0.0096 16.0 2.5 0.015 15.4 2.5 1.3 1 0 0 1 1 1 1 Prefoldin subunit APG6_N PF17675.1 KXG48712.1 - 0.015 15.8 16.9 0.035 14.6 4.4 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region PHM7_cyt PF14703.6 KXG48712.1 - 0.022 15.0 4.0 0.04 14.1 4.0 1.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Uds1 PF15456.6 KXG48712.1 - 0.031 14.4 4.0 0.047 13.9 4.0 1.2 1 0 0 1 1 1 0 Up-regulated During Septation DUF3727 PF12527.8 KXG48712.1 - 0.034 14.4 2.6 1.7 9.0 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3727) bZIP_1 PF00170.21 KXG48712.1 - 0.043 13.9 7.0 0.82 9.8 0.4 2.6 2 1 1 3 3 3 0 bZIP transcription factor TMF_TATA_bd PF12325.8 KXG48712.1 - 0.05 13.8 10.9 0.67 10.2 2.4 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 KXG48712.1 - 0.054 12.4 12.2 0.078 11.9 12.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 KXG48712.1 - 0.068 12.9 15.6 0.8 9.5 1.5 3.1 2 1 1 3 3 3 0 Septum formation initiator THOC7 PF05615.13 KXG48712.1 - 0.07 13.4 10.1 0.18 12.1 10.1 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 Prefoldin PF02996.17 KXG48712.1 - 0.078 12.9 11.3 0.23 11.4 11.3 1.7 1 1 0 1 1 1 0 Prefoldin subunit XhlA PF10779.9 KXG48712.1 - 0.11 12.7 0.4 0.11 12.7 0.4 1.8 2 0 0 2 2 2 0 Haemolysin XhlA DUF5082 PF16888.5 KXG48712.1 - 0.11 12.7 10.7 0.78 10.0 10.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Chibby PF14645.6 KXG48712.1 - 0.15 12.5 5.9 3.5 8.0 1.5 2.9 1 1 2 3 3 3 0 Chibby family Occludin_ELL PF07303.13 KXG48712.1 - 0.15 12.8 5.0 0.61 10.8 0.3 2.2 2 1 0 2 2 2 0 Occludin homology domain GAS PF13851.6 KXG48712.1 - 0.16 11.3 11.9 1.1 8.6 2.3 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KXG48712.1 - 0.2 11.7 14.2 0.58 10.2 2.5 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HAP1_N PF04849.13 KXG48712.1 - 0.21 10.7 12.2 0.76 8.9 12.3 1.7 1 1 0 1 1 1 0 HAP1 N-terminal conserved region FlaC_arch PF05377.11 KXG48712.1 - 0.31 11.5 11.0 1.2 9.6 2.5 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Rx_N PF18052.1 KXG48712.1 - 0.35 11.2 8.3 0.94 9.8 1.5 2.3 2 1 0 2 2 2 0 Rx N-terminal domain DUF4407 PF14362.6 KXG48712.1 - 0.43 9.9 8.7 0.62 9.4 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 KXG48712.1 - 0.48 10.9 4.7 7.6 7.1 1.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein JIP_LZII PF16471.5 KXG48712.1 - 0.52 10.5 9.4 1.5 9.1 1.7 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II WEMBL PF05701.11 KXG48712.1 - 0.58 8.8 16.0 0.39 9.3 5.5 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light CorA PF01544.18 KXG48712.1 - 0.75 9.1 5.7 1.1 8.6 2.5 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DHR10 PF18595.1 KXG48712.1 - 0.76 9.9 16.0 0.33 11.0 3.8 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Osmo_CC PF08946.10 KXG48712.1 - 0.91 9.8 7.9 0.16 12.3 2.1 2.3 2 1 0 2 2 2 0 Osmosensory transporter coiled coil BRE1 PF08647.11 KXG48712.1 - 1 9.5 12.3 1.6 8.8 3.1 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase YabA PF06156.13 KXG48712.1 - 1 10.0 10.3 6 7.6 2.4 2.1 1 1 1 2 2 2 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 KXG48712.1 - 1.4 9.3 16.3 2.2 8.6 0.5 3.2 2 2 1 3 3 3 0 ABC transporter C-terminal domain UPF0242 PF06785.11 KXG48712.1 - 1.5 8.9 16.3 1.3 9.1 3.3 2.0 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Snapin_Pallidin PF14712.6 KXG48712.1 - 2.3 8.7 10.3 0.28 11.6 0.8 2.3 2 1 0 2 2 2 0 Snapin/Pallidin DUF1664 PF07889.12 KXG48712.1 - 2.4 8.2 8.5 3.1 7.8 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fmp27_WPPW PF10359.9 KXG48712.1 - 2.9 6.6 9.3 3.9 6.2 2.3 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain TolA_bind_tri PF16331.5 KXG48712.1 - 3.3 7.8 16.2 3.6 7.7 6.9 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation Siah-Interact_N PF09032.11 KXG48712.1 - 3.4 8.0 12.2 1.4 9.3 2.7 2.4 2 1 0 2 2 2 0 Siah interacting protein, N terminal Sec34 PF04136.15 KXG48712.1 - 3.6 7.5 8.6 10 6.0 1.2 2.1 2 0 0 2 2 2 0 Sec34-like family FTA4 PF13093.6 KXG48712.1 - 4.6 7.1 10.3 1.4 8.8 2.9 2.0 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 LPP PF04728.13 KXG48712.1 - 4.9 7.6 10.1 12 6.3 0.9 2.8 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Csm1_N PF18504.1 KXG48712.1 - 5 7.5 11.7 6.8 7.1 0.8 3.1 2 1 1 3 3 3 0 Csm1 N-terminal domain SlyX PF04102.12 KXG48712.1 - 7 7.3 13.9 1.8 9.3 1.6 2.8 2 1 0 2 2 2 0 SlyX DUF724 PF05266.14 KXG48712.1 - 7.1 6.4 10.8 91 2.8 10.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) ERM PF00769.19 KXG48712.1 - 9.6 5.9 16.6 31 4.3 16.6 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family AAA PF00004.29 KXG48713.1 - 4.6e-42 143.6 0.0 8.4e-42 142.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KXG48713.1 - 1.1e-29 102.2 0.0 4.4e-29 100.3 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KXG48713.1 - 2e-23 82.3 2.0 2e-23 82.3 2.0 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KXG48713.1 - 4.9e-06 26.3 0.0 1.9e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KXG48713.1 - 9.3e-06 25.5 0.0 2.3e-05 24.2 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXG48713.1 - 1.2e-05 25.7 0.1 0.00016 22.1 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KXG48713.1 - 2.5e-05 24.3 0.0 0.00012 22.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KXG48713.1 - 2.8e-05 23.4 0.0 0.0011 18.2 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KXG48713.1 - 5.2e-05 23.6 0.0 0.011 16.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 KXG48713.1 - 7.4e-05 22.6 0.0 0.00016 21.4 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 KXG48713.1 - 0.00011 22.4 0.0 0.0068 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXG48713.1 - 0.00011 22.5 0.1 0.02 15.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 KXG48713.1 - 0.00011 21.5 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 KXG48713.1 - 0.00034 20.7 0.0 0.00068 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXG48713.1 - 0.0004 20.9 0.0 0.0022 18.5 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.6 KXG48713.1 - 0.0013 18.5 0.0 0.011 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXG48713.1 - 0.0015 18.7 0.0 0.0055 16.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXG48713.1 - 0.0076 15.8 0.2 0.64 9.6 0.1 2.9 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.6 KXG48713.1 - 0.0082 16.6 0.2 0.036 14.5 0.0 2.2 2 1 1 3 3 2 1 AAA domain AAA_7 PF12775.7 KXG48713.1 - 0.013 15.0 0.0 0.089 12.3 0.0 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KXG48713.1 - 0.02 14.3 0.1 0.07 12.5 0.1 2.0 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI USP8_dimer PF08969.11 KXG48713.1 - 0.023 14.9 3.5 0.048 13.8 3.5 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain ATPase_2 PF01637.18 KXG48713.1 - 0.041 13.8 0.9 1.3 8.9 0.0 2.9 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Torsin PF06309.11 KXG48713.1 - 0.044 13.9 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Torsin Parvo_NS1 PF01057.17 KXG48713.1 - 0.061 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 KXG48713.1 - 0.067 12.6 0.1 0.16 11.4 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 KXG48713.1 - 0.083 12.8 0.0 0.67 9.9 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Cytidylate_kin PF02224.18 KXG48713.1 - 0.12 12.1 0.2 0.5 10.1 0.0 2.1 3 0 0 3 3 2 0 Cytidylate kinase Bac_DnaA PF00308.18 KXG48713.1 - 0.13 12.1 0.0 0.57 10.0 0.0 2.0 1 1 0 1 1 1 0 Bacterial dnaA protein AFG1_ATPase PF03969.16 KXG48713.1 - 0.14 11.0 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase Cnn_1N PF07989.11 KXG48714.1 - 2.1e-22 79.1 5.8 2.1e-22 79.1 5.8 14.6 7 5 8 15 15 15 3 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 KXG48714.1 - 6.3e-22 78.0 1.4 6.3e-22 78.0 1.4 4.3 3 1 0 3 3 3 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Pox_A_type_inc PF04508.12 KXG48714.1 - 2.3 8.2 0.0 2.3 8.2 0.0 9.9 10 0 0 10 10 10 0 Viral A-type inclusion protein repeat SGT1 PF07093.11 KXG48715.1 - 4.5e-93 312.7 19.0 1.2e-86 291.4 0.1 2.1 1 1 1 2 2 2 2 SGT1 protein Folliculin PF11704.8 KXG48716.1 - 3.3e-52 177.1 0.0 6.7e-52 176.1 0.0 1.5 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport 3Beta_HSD PF01073.19 KXG48717.1 - 3.5e-10 39.3 0.8 3.9e-10 39.2 0.8 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXG48717.1 - 3.5e-07 29.9 0.1 4.2e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXG48717.1 - 4.9e-06 26.3 1.4 6.4e-06 25.9 1.4 1.2 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KXG48717.1 - 0.00011 21.8 0.0 0.00014 21.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Stevor PF17410.2 KXG48718.1 - 0.031 13.8 1.7 0.051 13.1 1.1 1.5 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame PPTA PF01239.22 KXG48718.1 - 0.045 13.5 0.5 0.14 11.9 0.5 1.8 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat CSN8_PSD8_EIF3K PF10075.9 KXG48719.1 - 4.1e-49 166.3 0.0 5.3e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family FGAR-AT_linker PF18072.1 KXG48719.1 - 0.11 13.0 0.1 10 6.7 0.1 2.6 2 1 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain PDCD2_C PF04194.13 KXG48720.1 - 6e-42 143.7 0.0 3e-41 141.4 0.0 2.0 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain A2L_zn_ribbon PF08792.10 KXG48720.1 - 0.14 11.9 0.4 7.5 6.4 0.1 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain Prenylcys_lyase PF07156.14 KXG48721.1 - 6.9e-93 311.6 0.0 9.6e-93 311.2 0.0 1.2 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KXG48721.1 - 2.8e-13 49.9 0.0 6.3e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXG48721.1 - 7.9e-10 38.6 0.0 7.6e-09 35.4 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KXG48721.1 - 4.8e-08 33.0 0.1 1.2e-05 25.1 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXG48721.1 - 0.0015 18.5 0.2 0.012 15.6 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXG48721.1 - 0.002 17.4 0.1 0.076 12.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXG48721.1 - 0.034 12.9 0.1 0.23 10.1 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Peptidase_M17_N PF02789.17 KXG48721.1 - 0.056 13.3 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain TPP_enzyme_M PF00205.22 KXG48721.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain ApbA PF02558.16 KXG48721.1 - 0.078 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KXG48721.1 - 0.079 13.5 0.2 8.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GATase PF00117.28 KXG48722.1 - 2.5e-41 141.5 0.0 4.2e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KXG48722.1 - 5.8e-36 122.4 0.0 1.3e-35 121.3 0.0 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 KXG48722.1 - 1.5e-09 37.3 0.0 5.5e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KXG48722.1 - 2.3e-05 24.3 0.1 7.9e-05 22.5 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 KXG48722.1 - 7.5e-05 21.7 0.1 0.00019 20.4 0.1 1.6 2 0 0 2 2 2 1 tRNA methyl transferase Arginosuc_synth PF00764.19 KXG48722.1 - 0.0009 18.6 0.1 0.0013 18.1 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase PAPS_reduct PF01507.19 KXG48722.1 - 0.0012 18.9 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 KXG48722.1 - 0.007 15.9 0.0 0.051 13.1 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 KXG48722.1 - 0.019 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 KXG48722.1 - 0.19 11.4 0.0 0.43 10.3 0.0 1.6 2 0 0 2 2 2 0 PP-loop family CLP1_P PF16575.5 KXG48723.1 - 8.3e-27 94.2 0.0 1.5e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_helicase PF00910.22 KXG48723.1 - 0.043 14.2 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KXG48723.1 - 0.059 13.5 2.8 0.099 12.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KXG48723.1 - 0.082 13.5 0.2 0.27 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXG48723.1 - 0.11 12.9 0.2 3.3 8.1 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain G-alpha PF00503.20 KXG48723.1 - 0.16 11.1 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 KXG48723.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_polI_A34 PF08208.11 KXG48724.1 - 1.9e-42 145.7 17.9 1.9e-42 145.7 17.9 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF2052 PF09747.9 KXG48724.1 - 0.31 11.1 15.2 0.81 9.8 5.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Sporozoite_P67 PF05642.11 KXG48724.1 - 0.99 7.4 17.0 0.044 11.9 6.1 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen FAM60A PF15396.6 KXG48724.1 - 2.7 7.9 15.5 5.3 7.0 6.1 2.4 2 0 0 2 2 2 0 Protein Family FAM60A GRAM PF02893.20 KXG48725.1 - 2.9e-35 120.6 2.0 3.4e-23 81.7 0.1 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 KXG48725.1 - 4e-26 91.7 0.0 7.6e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 KXG48725.1 - 1e-14 54.9 0.1 9.8e-14 51.7 0.0 2.5 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 KXG48725.1 - 3.2e-06 27.5 1.0 9.8e-05 22.7 1.0 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KXG48725.1 - 0.00015 21.8 0.0 0.00032 20.8 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KXG48725.1 - 0.00023 21.4 0.0 0.00056 20.1 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DUF4288 PF14119.6 KXG48725.1 - 0.023 15.1 0.0 0.059 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) UDPGT PF00201.18 KXG48725.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase PH_6 PF15406.6 KXG48725.1 - 0.13 12.5 0.0 0.41 10.9 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Prefoldin PF02996.17 KXG48726.1 - 2.1e-29 101.9 0.3 3.5e-29 101.1 0.2 1.4 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 KXG48726.1 - 6.7e-05 22.8 0.6 0.00023 21.1 0.1 2.0 2 1 0 2 2 2 1 Prefoldin subunit DUF4201 PF13870.6 KXG48726.1 - 0.0078 16.0 0.9 0.13 12.0 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Syntaxin-6_N PF09177.11 KXG48726.1 - 0.01 16.4 1.9 1.9 9.1 1.9 2.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal End3 PF12761.7 KXG48726.1 - 0.019 15.1 0.5 0.038 14.1 0.5 1.7 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 FlaC_arch PF05377.11 KXG48726.1 - 0.11 12.9 3.6 1.1 9.7 0.1 3.0 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Vma12 PF11712.8 KXG48727.1 - 5.3e-37 127.0 0.0 7e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Amidohydro_1 PF01979.20 KXG48728.1 - 1.4e-29 103.5 0.0 2.7e-29 102.6 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXG48728.1 - 4.7e-12 46.1 0.0 7.8e-07 28.9 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.14 KXG48728.1 - 0.097 12.4 0.0 0.27 11.0 0.0 1.8 1 1 0 1 1 1 0 Amidohydrolase 5-nucleotidase PF06189.12 KXG48728.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase LAT PF15234.6 KXG48729.1 - 0.025 14.3 0.7 0.039 13.7 0.7 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells Glyco_H_20C_C PF18088.1 KXG48729.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycoside Hydrolase 20C C-terminal domain Ribosomal_S14 PF00253.21 KXG48730.1 - 3.3e-21 74.8 1.3 3.8e-21 74.6 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e SpoIIIAH PF12685.7 KXG48730.1 - 0.25 11.1 1.0 0.44 10.4 0.3 1.7 1 1 1 2 2 2 0 SpoIIIAH-like protein DASH_Spc19 PF08287.11 KXG48731.1 - 4.2e-53 179.5 4.5 5.7e-53 179.0 4.5 1.2 1 0 0 1 1 1 1 Spc19 Mur_ligase_M PF08245.12 KXG48731.1 - 0.018 15.0 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Mur ligase middle domain Rsm22 PF09243.10 KXG48732.1 - 1.4e-31 109.8 0.0 1.2e-29 103.4 0.0 2.6 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Rogdi_lz PF10259.9 KXG48733.1 - 3.7e-86 288.9 0.2 4.2e-86 288.7 0.2 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein SUR7 PF06687.12 KXG48734.1 - 1.2e-38 132.9 8.4 1.4e-38 132.6 8.4 1.0 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.12 KXG48734.1 - 0.0016 18.0 0.9 0.0033 16.9 0.9 1.5 1 0 0 1 1 1 1 Clc-like Claudin_2 PF13903.6 KXG48734.1 - 0.026 14.3 9.7 0.026 14.3 7.4 2.2 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF4491 PF14898.6 KXG48734.1 - 0.15 12.6 4.7 2.5 8.6 1.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4491) Amastin PF07344.11 KXG48734.1 - 0.77 9.6 13.6 0.017 14.9 6.9 1.7 2 1 0 2 2 2 0 Amastin surface glycoprotein HSP70 PF00012.20 KXG48735.1 - 7e-82 275.5 0.7 7e-82 275.5 0.7 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXG48735.1 - 1e-09 37.7 0.1 1.6e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Peripla_BP_6 PF13458.6 KXG48735.1 - 0.0029 17.3 0.6 0.0052 16.5 0.4 1.5 1 1 0 1 1 1 1 Periplasmic binding protein KH_6 PF15985.5 KXG48736.1 - 1.7e-16 60.3 0.1 4.3e-16 59.0 0.0 1.7 2 0 0 2 2 2 1 KH domain Rrp40_N PF18311.1 KXG48736.1 - 6.8e-10 38.7 0.6 2.1e-09 37.1 0.6 1.9 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain Myb_DNA-bind_6 PF13921.6 KXG48737.1 - 3.4e-17 62.4 3.2 5.9e-11 42.4 1.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXG48737.1 - 4e-16 58.9 9.4 3.9e-08 33.4 0.6 3.5 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KXG48737.1 - 6.4e-05 23.2 0.1 6.4e-05 23.2 0.1 3.1 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 KXG48737.1 - 0.064 13.5 1.8 0.91 9.8 0.1 2.4 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Glyco_transf_24 PF18404.1 KXG48738.1 - 2.4e-147 489.5 1.1 3.8e-147 488.8 1.1 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KXG48738.1 - 9.6e-68 228.9 0.0 3.6e-65 220.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KXG48738.1 - 2.8e-44 151.6 0.2 1.9e-43 148.9 0.4 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KXG48738.1 - 1.1e-42 145.1 1.3 3.2e-42 143.7 0.0 2.4 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KXG48738.1 - 1.2e-41 141.2 0.0 2.4e-41 140.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_12 PF18400.1 KXG48738.1 - 2.7e-39 135.0 0.6 1.1e-22 80.8 0.4 2.6 1 1 1 2 2 2 2 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KXG48738.1 - 0.00084 19.0 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 TINF2_N PF14973.6 KXG48739.1 - 0.08 13.3 0.0 0.45 10.9 0.0 2.0 1 1 1 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus Rpp20 PF12328.8 KXG48740.1 - 1.7e-48 164.0 17.6 4.4e-48 162.7 17.6 1.6 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KXG48740.1 - 4.9e-20 71.1 1.4 8.4e-20 70.4 1.4 1.4 1 0 0 1 1 1 1 Alba ATG2_CAD PF13329.6 KXG48740.1 - 0.1 12.4 0.2 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif Presenilin PF01080.17 KXG48740.1 - 0.36 9.5 6.5 0.46 9.2 6.5 1.1 1 0 0 1 1 1 0 Presenilin FHA PF00498.26 KXG48741.1 - 2.8e-16 59.6 0.0 5.5e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXG48741.1 - 0.00084 19.6 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain LMP PF04778.12 KXG48741.1 - 0.0077 16.2 2.4 0.0077 16.2 2.4 2.3 3 0 0 3 3 3 1 LMP repeated region YhfZ_C PF14503.6 KXG48741.1 - 0.0087 15.6 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 YhfZ C-terminal domain DUF3080 PF11279.8 KXG48741.1 - 0.012 14.9 1.1 0.012 14.9 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3080) VWA_2 PF13519.6 KXG48741.1 - 0.11 13.1 1.4 0.57 10.9 0.2 2.7 3 0 0 3 3 3 0 von Willebrand factor type A domain IL6 PF00489.17 KXG48741.1 - 0.41 10.2 3.2 3.2 7.3 0.6 2.3 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family DUF2408 PF10303.9 KXG48741.1 - 0.99 10.0 9.1 0.051 14.1 1.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) EMP24_GP25L PF01105.24 KXG48741.1 - 1.6 8.7 4.7 0.54 10.2 0.3 2.4 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD COG2 PF06148.11 KXG48741.1 - 2.2 8.4 13.5 0.28 11.3 4.1 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FUSC PF04632.12 KXG48741.1 - 2.6 6.5 4.3 0.98 7.9 1.3 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF2203 PF09969.9 KXG48741.1 - 2.9 8.7 12.8 6.6 7.5 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF1366 PF07104.11 KXG48741.1 - 6.3 6.5 11.6 27 4.5 4.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1366) Romo1 PF10247.9 KXG48742.1 - 3.8e-28 97.7 16.2 5e-28 97.3 16.2 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KXG48742.1 - 0.00029 21.2 2.8 0.00036 20.9 2.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TMEM141 PF15110.6 KXG48742.1 - 2.5 8.7 4.7 3.1 8.4 0.8 2.1 1 1 0 2 2 2 0 TMEM141 protein family ABC_tran PF00005.27 KXG48743.1 - 1.5e-34 119.4 0.0 3.2e-34 118.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KXG48743.1 - 2.4e-22 79.9 4.9 4.4e-22 79.0 4.9 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KXG48743.1 - 7e-08 32.2 0.0 7.5e-06 25.5 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KXG48743.1 - 0.0046 16.7 0.3 0.0078 16.0 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 KXG48743.1 - 0.0097 15.2 0.7 0.053 12.8 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 KXG48743.1 - 0.011 16.1 0.1 0.025 15.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KXG48743.1 - 0.011 16.2 1.3 0.011 16.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.6 KXG48743.1 - 0.013 15.7 0.1 0.041 14.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 KXG48743.1 - 0.023 14.8 0.0 0.079 13.0 0.0 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_21 PF13304.6 KXG48743.1 - 0.036 13.9 0.1 0.092 12.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXG48743.1 - 0.037 13.8 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 KXG48743.1 - 0.038 13.2 0.2 0.086 12.0 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 KXG48743.1 - 0.048 14.1 0.1 0.35 11.3 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KXG48743.1 - 0.06 13.1 0.1 0.15 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXG48743.1 - 0.064 13.8 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KXG48743.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase TMEM208_SND2 PF05620.11 KXG48743.1 - 0.13 12.0 0.3 0.73 9.6 0.2 2.2 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 MMR_HSR1 PF01926.23 KXG48743.1 - 0.14 12.3 0.0 0.42 10.7 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 KXG48743.1 - 0.15 11.6 0.0 0.38 10.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KXG48743.1 - 0.18 11.9 0.1 2.1 8.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 KXG48743.1 - 0.18 11.8 0.1 0.34 10.9 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RPN2_C PF18004.1 KXG48743.1 - 0.25 11.2 1.2 0.57 10.1 1.2 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Sporozoite_P67 PF05642.11 KXG48744.1 - 0.94 7.5 13.0 1 7.4 13.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BES1_N PF05687.13 KXG48744.1 - 1.2 9.5 6.5 1.5 9.2 6.5 1.1 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal MAP65_ASE1 PF03999.12 KXG48744.1 - 1.8 7.2 8.2 1.9 7.1 8.2 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) adh_short PF00106.25 KXG48745.1 - 1e-35 123.0 0.0 1.6e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG48745.1 - 2.6e-28 99.2 0.0 4.1e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG48745.1 - 5.2e-11 42.8 0.0 7.5e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 KR domain LRR_8 PF13855.6 KXG48745.1 - 1.2e-09 37.8 9.9 1.6e-08 34.2 7.6 2.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KXG48745.1 - 3.8e-06 27.2 1.6 3.8e-06 27.2 1.6 3.2 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) Epimerase PF01370.21 KXG48745.1 - 0.017 14.6 0.1 0.12 11.8 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXG48745.1 - 0.044 12.9 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain LRR_1 PF00560.33 KXG48745.1 - 0.26 12.0 6.2 77 4.4 0.1 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat zf-RING_2 PF13639.6 KXG48746.1 - 3.1e-12 46.6 5.4 5.1e-12 45.9 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXG48746.1 - 1.1e-08 35.2 2.0 2.3e-08 34.2 2.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXG48746.1 - 1.8e-08 34.1 4.1 3e-08 33.4 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KXG48746.1 - 6.2e-08 32.6 0.0 1.4e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-RING_11 PF17123.5 KXG48746.1 - 1.1e-07 31.4 2.4 1.1e-07 31.4 2.4 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXG48746.1 - 1.2e-07 31.5 3.3 2e-07 30.8 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXG48746.1 - 1.3e-06 28.2 2.4 2.1e-06 27.6 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXG48746.1 - 4.2e-05 23.3 3.1 6.5e-05 22.7 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXG48746.1 - 4.6e-05 23.4 2.4 7.3e-05 22.7 0.6 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXG48746.1 - 0.002 18.1 1.1 0.0039 17.2 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXG48746.1 - 0.023 14.5 2.7 0.043 13.7 2.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXG48746.1 - 0.15 12.3 3.7 0.32 11.2 3.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KXG48746.1 - 0.32 10.6 2.3 0.61 9.8 2.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KXG48746.1 - 0.5 10.6 2.5 1.4 9.2 2.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KXG48746.1 - 0.55 10.6 2.9 1.1 9.6 2.9 1.5 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 KXG48746.1 - 0.69 10.1 3.5 1.4 9.1 3.5 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 KXG48746.1 - 1.5 8.7 2.9 2.9 7.7 2.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Raptor_N PF14538.6 KXG48749.1 - 2.9e-64 215.4 0.0 5.4e-64 214.6 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KXG48749.1 - 5.7e-05 23.8 11.0 0.83 10.6 0.1 6.6 5 1 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 KXG48749.1 - 0.0032 17.5 0.1 3.3 7.8 0.0 2.7 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.22 KXG48749.1 - 0.12 12.7 1.3 28 5.3 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat Kelch_3 PF13415.6 KXG48750.1 - 2.2e-33 113.9 8.2 3.2e-06 27.3 0.1 6.0 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KXG48750.1 - 2.6e-32 110.6 8.0 5.8e-07 29.4 0.8 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KXG48750.1 - 5.8e-28 96.4 7.1 8.4e-06 25.6 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 KXG48750.1 - 7.5e-28 95.9 3.3 5.5e-11 41.9 0.7 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KXG48750.1 - 2.5e-25 87.9 6.3 2.1e-08 34.2 0.8 6.3 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KXG48750.1 - 1.1e-18 66.4 8.8 1.5e-06 27.9 0.5 6.5 6 0 0 6 6 6 4 Kelch motif RAG2 PF03089.14 KXG48750.1 - 0.099 11.6 0.1 1.2 8.0 0.0 2.7 3 1 1 4 4 4 0 Recombination activating protein 2 Strep_SA_rep PF06696.11 KXG48750.1 - 1.9 8.5 5.4 3.6 7.7 1.0 3.2 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Pkinase PF00069.25 KXG48751.1 - 5.5e-26 91.5 0.0 7.3e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48751.1 - 7.3e-14 51.7 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXG48751.1 - 5e-09 35.4 0.0 7.3e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXG48751.1 - 0.00022 21.2 0.0 0.0016 18.4 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family bZIP_1 PF00170.21 KXG48752.1 - 3.5e-10 39.8 9.3 8.2e-10 38.6 9.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXG48752.1 - 4.1e-05 23.6 14.9 5.3e-05 23.2 13.1 1.9 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXG48752.1 - 0.0075 16.8 11.5 0.013 16.0 11.5 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor MIS13 PF08202.11 KXG48752.1 - 0.009 15.3 2.3 0.012 14.9 2.3 1.1 1 0 0 1 1 1 1 Mis12-Mtw1 protein family ZapB PF06005.12 KXG48752.1 - 0.013 15.9 5.3 0.013 15.9 5.3 1.8 1 1 1 2 2 2 0 Cell division protein ZapB PAP1 PF08601.10 KXG48752.1 - 0.018 14.8 12.8 0.64 9.7 0.0 2.0 2 0 0 2 2 2 0 Transcription factor PAP1 DUF5595 PF18077.1 KXG48752.1 - 0.022 14.9 1.8 0.039 14.0 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) YabA PF06156.13 KXG48752.1 - 0.028 15.1 0.8 0.047 14.3 0.8 1.4 1 0 0 1 1 1 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 KXG48752.1 - 0.03 14.6 6.7 0.05 13.8 6.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF5094 PF17015.5 KXG48752.1 - 0.04 14.0 6.5 0.056 13.5 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) V_ATPase_I PF01496.19 KXG48752.1 - 0.048 11.6 4.3 0.061 11.2 4.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF3_subunit PF08597.10 KXG48752.1 - 0.051 13.5 5.9 0.068 13.1 5.9 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DivIC PF04977.15 KXG48752.1 - 0.069 12.9 5.2 0.12 12.1 5.2 1.4 1 0 0 1 1 1 0 Septum formation initiator SHE3 PF17078.5 KXG48752.1 - 0.07 12.8 5.3 0.095 12.4 5.3 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 HALZ PF02183.18 KXG48752.1 - 0.07 13.4 1.8 0.12 12.6 1.8 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper PSI_PsaF PF02507.15 KXG48752.1 - 0.13 12.1 1.4 0.21 11.4 1.4 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III GvpL_GvpF PF06386.11 KXG48752.1 - 0.23 11.3 4.0 0.35 10.8 4.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF NRBF2 PF08961.10 KXG48752.1 - 0.62 9.6 6.3 1.2 8.7 6.2 1.5 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator dsrm PF00035.26 KXG48752.1 - 0.75 10.5 2.5 2.3 9.0 2.5 1.9 1 1 0 1 1 1 0 Double-stranded RNA binding motif UPF0242 PF06785.11 KXG48752.1 - 1 9.4 6.5 1.5 8.9 6.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 KXG48752.1 - 2.1 7.4 7.6 3 6.9 7.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4554 PF15091.6 KXG48752.1 - 3.8 6.3 5.1 5.1 5.9 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) DUF4407 PF14362.6 KXG48752.1 - 4.5 6.5 6.0 6.9 5.9 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phosducin PF02114.16 KXG48753.1 - 4.7e-12 45.4 0.1 5.9e-12 45.1 0.1 1.2 1 0 0 1 1 1 1 Phosducin Adaptin_N PF01602.20 KXG48754.1 - 1.1e-111 374.0 0.2 1.4e-111 373.7 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KXG48754.1 - 1e-57 194.5 2.4 2.7e-57 193.2 2.4 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KXG48754.1 - 1.8e-33 115.1 0.3 9.3e-33 112.8 0.1 2.4 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KXG48754.1 - 7.9e-18 64.6 0.3 1.8e-11 44.2 0.0 5.4 4 1 2 6 6 6 1 HEAT repeats Cnd1 PF12717.7 KXG48754.1 - 2.3e-10 40.8 6.1 0.00021 21.4 0.1 5.0 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXG48754.1 - 0.00023 21.1 4.9 0.2 12.0 0.1 5.5 6 0 0 6 6 6 1 HEAT repeat HEAT_PBS PF03130.16 KXG48754.1 - 0.0023 18.4 0.8 14 6.7 0.0 5.0 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.9 KXG48754.1 - 0.0071 14.9 0.5 0.52 8.8 0.0 3.0 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.6 KXG48754.1 - 0.0086 16.6 0.7 0.049 14.2 0.2 2.6 2 0 0 2 2 2 1 HEAT-like repeat DUF1548 PF07579.11 KXG48754.1 - 0.15 12.4 0.2 0.94 9.8 0.1 2.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1548) tRNA-synt_2 PF00152.20 KXG48755.1 - 8.8e-72 241.8 0.1 1.2e-71 241.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXG48755.1 - 7.1e-07 29.1 0.1 1.4e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Hydrolase_6 PF13344.6 KXG48756.1 - 2.5e-25 88.5 0.0 4.3e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXG48756.1 - 8.2e-17 61.0 0.0 3.5e-16 59.0 0.0 2.1 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.26 KXG48756.1 - 8.5e-06 26.2 0.0 0.1 12.9 0.1 3.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXG48756.1 - 0.038 14.4 0.0 6.2 7.2 0.0 2.6 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXG48756.1 - 0.039 14.0 0.0 10 6.1 0.0 2.6 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase F-box-like PF12937.7 KXG48757.1 - 0.018 15.0 0.4 0.018 15.0 0.4 2.3 2 0 0 2 2 2 0 F-box-like SIP1 PF04938.12 KXG48758.1 - 6.2e-14 52.2 0.0 4.3e-11 43.0 0.0 2.4 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) PX PF00787.24 KXG48759.1 - 4.3e-13 49.2 0.0 1e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 PX domain BCIP PF13862.6 KXG48759.1 - 0.032 14.0 0.1 0.061 13.1 0.1 1.4 1 0 0 1 1 1 0 p21-C-terminal region-binding protein Ank_2 PF12796.7 KXG48760.1 - 1.3e-58 195.6 0.5 2e-16 60.4 0.0 8.9 5 2 4 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG48760.1 - 6.3e-47 157.4 2.5 1.6e-06 28.6 0.0 11.8 8 4 6 14 14 14 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG48760.1 - 1.5e-44 144.8 8.4 0.00013 22.1 0.0 16.1 16 0 0 16 16 16 10 Ankyrin repeat Ank_5 PF13857.6 KXG48760.1 - 2.7e-33 113.6 8.2 0.00025 21.3 0.0 14.1 11 2 5 16 16 16 8 Ankyrin repeats (many copies) Ank PF00023.30 KXG48760.1 - 9.4e-31 104.9 14.8 0.00036 20.9 0.0 13.6 14 0 0 14 14 14 7 Ankyrin repeat SpoU_sub_bind PF08032.12 KXG48760.1 - 0.087 13.1 0.1 25 5.3 0.0 4.6 7 0 0 7 7 7 0 RNA 2'-O ribose methyltransferase substrate binding Cyclase PF04199.13 KXG48762.1 - 4e-14 53.0 0.1 6e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.12 KXG48762.1 - 0.057 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Sugar_tr PF00083.24 KXG48763.1 - 1.7e-77 261.2 23.3 2.8e-77 260.5 23.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG48763.1 - 1.9e-20 73.1 38.1 2.4e-14 53.0 17.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KXG48764.1 - 7.7e-10 38.2 0.0 1.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.25 KXG48764.1 - 7.6e-07 29.4 0.0 1.9e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXG48764.1 - 0.0053 17.2 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXG48764.1 - 0.0085 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ecotin PF03974.13 KXG48764.1 - 0.024 14.6 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 Ecotin PIN_12 PF16289.5 KXG48764.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 PIN domain Homeodomain PF00046.29 KXG48765.1 - 5.4e-15 55.0 2.2 1.2e-14 53.9 2.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXG48765.1 - 0.048 13.6 0.1 0.17 11.8 0.1 1.9 1 0 0 1 1 1 0 Homeobox KN domain Amino_oxidase PF01593.24 KXG48766.1 - 3e-55 188.3 0.1 9.5e-55 186.7 0.1 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXG48766.1 - 4e-16 59.0 0.2 1.1e-15 57.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXG48766.1 - 6.2e-07 29.5 0.9 0.017 15.1 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXG48766.1 - 7.7e-07 28.6 0.3 2.9e-05 23.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG48766.1 - 4.2e-05 23.3 6.0 0.00042 20.0 6.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXG48766.1 - 7.9e-05 21.5 0.6 0.00098 17.9 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KXG48766.1 - 8.3e-05 23.1 1.0 0.00016 22.2 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG48766.1 - 0.0017 17.5 0.0 0.0029 16.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXG48766.1 - 0.0095 15.2 0.2 0.016 14.5 0.2 1.2 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KXG48766.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KXG48766.1 - 0.012 14.9 2.5 1.4 8.1 0.6 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Prenylcys_lyase PF07156.14 KXG48766.1 - 0.014 14.5 0.1 0.021 14.0 0.1 1.1 1 0 0 1 1 1 0 Prenylcysteine lyase FAD_oxidored PF12831.7 KXG48766.1 - 0.016 14.6 1.1 0.023 14.1 0.7 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXG48766.1 - 0.018 14.3 0.4 0.031 13.5 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KXG48766.1 - 0.1 12.5 0.4 0.19 11.6 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tantalus PF15386.6 KXG48767.1 - 0.11 12.5 0.1 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Drosophila Tantalus-like DUF2235 PF09994.9 KXG48769.1 - 1.5e-102 342.9 0.1 1.9e-102 342.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.15 KXG48770.1 - 5.6e-37 127.5 0.0 3.2e-23 82.1 0.0 3.3 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KXG48770.1 - 5.1e-05 22.2 0.1 0.00089 18.1 0.0 2.1 2 0 0 2 2 2 1 Cytochrome P450 PilP PF04351.13 KXG48770.1 - 0.098 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Pilus assembly protein, PilP PHD PF00628.29 KXG48771.1 - 1.7e-10 40.6 7.1 1.7e-10 40.6 7.1 2.6 2 0 0 2 2 2 1 PHD-finger APH PF01636.23 KXG48771.1 - 0.006 16.5 0.0 0.049 13.6 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Neuropep_like PF15161.6 KXG48771.1 - 0.088 12.5 0.3 0.31 10.7 0.3 1.9 1 0 0 1 1 1 0 Neuropeptide-like ORC6 PF05460.13 KXG48771.1 - 1.2 8.4 13.5 3 7.0 13.5 1.6 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ndc1_Nup PF09531.10 KXG48771.1 - 1.8 7.2 3.2 2.9 6.5 3.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lys-AminoMut_A PF09043.11 KXG48772.1 - 0.048 12.1 0.0 0.075 11.5 0.0 1.2 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit zf-CCCH_6 PF18585.1 KXG48772.1 - 0.3 11.0 1.4 0.69 9.8 0.0 2.4 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 F-box-like PF12937.7 KXG48772.1 - 0.6 10.0 4.0 0.58 10.1 0.6 2.8 2 1 0 2 2 2 0 F-box-like Meth_synt_2 PF01717.18 KXG48773.1 - 2.6e-10 40.1 0.0 7.4e-07 28.7 0.0 2.5 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KXG48773.1 - 0.023 14.2 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain Arf PF00025.21 KXG48775.1 - 4.2e-71 238.0 0.1 4.9e-71 237.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXG48775.1 - 3.5e-16 59.5 0.1 4.8e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXG48775.1 - 3.5e-13 49.5 0.0 3.9e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KXG48775.1 - 6.9e-13 48.5 1.3 1.2e-08 34.6 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KXG48775.1 - 5.4e-12 45.5 0.0 6.6e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KXG48775.1 - 4.1e-10 39.4 0.0 4.7e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXG48775.1 - 7.1e-06 26.1 0.1 1.6e-05 25.0 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXG48775.1 - 0.0019 17.8 0.0 0.004 16.7 0.0 1.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KXG48775.1 - 0.0098 15.4 0.4 0.018 14.6 0.2 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B 6PF2K PF01591.18 KXG48775.1 - 0.017 14.4 0.3 0.03 13.6 0.3 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Glycos_transf_1 PF00534.20 KXG48776.1 - 9e-18 64.4 0.0 3.2e-17 62.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXG48776.1 - 1.8e-13 51.1 0.0 3.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KXG48776.1 - 5.4e-06 26.7 0.0 1.2e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 ThuA PF06283.11 KXG48776.1 - 0.081 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Trehalose utilisation Hexapep PF00132.24 KXG48777.1 - 1.1e-06 28.2 9.1 0.011 15.4 4.1 5.0 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXG48777.1 - 0.0086 15.8 0.4 0.0086 15.8 0.4 2.7 3 1 1 4 4 4 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KXG48777.1 - 0.13 11.2 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase KI67R PF08065.12 KXG48778.1 - 0.51 10.9 6.8 1.2 9.7 6.8 1.6 1 0 0 1 1 1 0 KI67R (NUC007) repeat AMP-binding PF00501.28 KXG48779.1 - 6.7e-77 258.9 0.0 1.5e-76 257.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KXG48779.1 - 1.5e-61 207.8 0.0 3.1e-61 206.8 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KXG48779.1 - 7.6e-52 175.6 3.1 1.5e-51 174.7 3.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG48779.1 - 3.5e-38 131.5 2.0 7e-38 130.5 2.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG48779.1 - 6.7e-18 65.2 3.0 2.1e-14 53.9 2.3 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KXG48779.1 - 2.5e-17 63.1 0.0 2.4e-09 37.0 0.0 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXG48779.1 - 2.8e-12 46.8 0.0 6.1e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KXG48779.1 - 1.4e-09 37.4 0.1 0.00014 21.0 0.0 3.2 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXG48779.1 - 7.7e-07 28.5 0.5 8.3e-05 21.8 0.0 2.7 3 0 0 3 3 3 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXG48779.1 - 4e-05 23.6 0.7 0.00021 21.3 0.9 2.2 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXG48779.1 - 0.0033 16.6 0.9 2 7.4 0.3 3.2 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein AMP-binding_C PF13193.6 KXG48779.1 - 0.02 15.8 0.1 0.14 13.1 0.0 2.7 2 0 0 2 2 1 0 AMP-binding enzyme C-terminal domain ApbA PF02558.16 KXG48779.1 - 0.03 14.0 0.1 0.064 12.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DFP PF04127.15 KXG48779.1 - 0.061 13.1 2.0 0.25 11.1 1.7 2.1 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein GDP_Man_Dehyd PF16363.5 KXG48779.1 - 0.072 12.5 0.0 2.3 7.5 0.0 2.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KXG48779.1 - 0.12 11.7 0.1 0.32 10.3 0.1 1.8 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.13 KXG48779.1 - 1.6 8.2 3.9 5.8 6.4 1.9 2.9 5 0 0 5 5 5 0 NmrA-like family Sugar_tr PF00083.24 KXG48780.1 - 4.1e-104 349.0 21.5 4.7e-104 348.8 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG48780.1 - 4.6e-28 98.2 40.7 7.6e-26 90.9 22.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG48780.1 - 4.2 6.1 18.0 1.8 7.3 8.9 2.4 2 0 0 2 2 2 0 MFS_1 like family Phage_holin_3_2 PF04550.12 KXG48780.1 - 4.9 7.8 9.2 1 9.9 3.6 2.7 3 0 0 3 3 3 0 Phage holin family 2 Fungal_trans PF04082.18 KXG48781.1 - 4.2e-28 98.1 0.0 7.1e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG48781.1 - 1.1e-10 41.4 12.9 2e-10 40.6 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4446 PF14584.6 KXG48781.1 - 0.24 11.4 0.0 0.46 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) 2OG-FeII_Oxy_3 PF13640.6 KXG48782.1 - 6.6e-13 49.4 0.1 1.2e-12 48.5 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-C2H2 PF00096.26 KXG48783.1 - 4.8e-07 29.9 15.3 3.4e-05 24.1 2.8 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXG48783.1 - 9.7e-06 25.8 5.7 2.7e-05 24.4 3.3 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXG48783.1 - 0.00011 22.7 1.7 0.00011 22.7 1.7 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXG48783.1 - 0.003 17.8 1.9 0.0039 17.5 0.7 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXG48783.1 - 0.004 17.1 1.3 0.0083 16.1 1.3 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KXG48783.1 - 0.009 16.3 2.8 0.02 15.2 2.8 1.6 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-TRAF PF02176.18 KXG48783.1 - 0.14 12.9 5.0 0.36 11.6 2.4 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger FOXP-CC PF16159.5 KXG48783.1 - 0.18 12.5 7.2 0.89 10.2 0.4 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-Di19 PF05605.12 KXG48783.1 - 3 8.2 8.1 13 6.1 0.4 2.4 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KXG48783.1 - 9.7 6.6 7.4 5.1 7.5 4.1 2.2 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Forkhead PF00250.18 KXG48784.1 - 2.3e-35 120.7 0.9 4.1e-35 119.9 0.9 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KXG48784.1 - 2.3e-08 34.3 0.0 6.1e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 FHA domain TENA_THI-4 PF03070.16 KXG48785.1 - 4.1e-10 39.8 0.0 5.1e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 TENA/THI-4/PQQC family ING PF12998.7 KXG48787.1 - 8.3e-07 29.5 0.0 2.1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KXG48787.1 - 4.3e-06 26.5 10.1 8.3e-06 25.6 10.1 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KXG48787.1 - 0.019 15.2 2.1 0.039 14.2 2.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain BrnA_antitoxin PF14384.6 KXG48787.1 - 0.065 13.7 0.8 14 6.3 0.0 3.5 2 0 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system zf-HC5HC2H_2 PF13832.6 KXG48787.1 - 0.13 12.4 2.1 0.23 11.6 2.1 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain PH_14 PF17787.1 KXG48787.1 - 0.27 11.1 2.5 0.15 12.0 0.2 1.7 2 0 0 2 2 2 0 PH domain GFO_IDH_MocA PF01408.22 KXG48788.1 - 2.4e-10 41.3 0.0 5.7e-10 40.1 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DHDPS PF00701.22 KXG48789.1 - 5.3e-33 114.0 0.0 1.5e-26 92.8 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family ADH_N PF08240.12 KXG48791.1 - 6.9e-26 90.3 4.2 1.2e-25 89.5 4.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG48791.1 - 9.9e-17 61.1 0.0 2.2e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXG48791.1 - 0.00019 20.8 0.1 0.00033 20.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.32 KXG48792.1 - 2.4e-28 97.8 11.9 5e-05 24.0 1.3 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.7 KXG48792.1 - 7.9e-11 41.7 0.2 1.7e-10 40.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KXG48792.1 - 5.8e-05 23.3 0.0 2 8.8 0.0 4.7 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KXG48792.1 - 0.00056 19.7 0.1 0.0011 18.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain PQQ PF01011.21 KXG48792.1 - 0.0018 18.1 0.1 3.5 7.7 0.0 3.5 3 0 0 3 3 3 1 PQQ enzyme repeat WD40_like PF17005.5 KXG48792.1 - 0.0025 17.2 0.1 0.022 14.1 0.1 2.2 2 0 0 2 2 2 1 WD40-like domain DUF5046 PF16465.5 KXG48792.1 - 0.012 15.1 0.3 0.2 11.1 0.0 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF5046) PQQ_2 PF13360.6 KXG48792.1 - 0.012 15.2 0.0 0.35 10.4 0.0 2.5 1 1 1 2 2 2 0 PQQ-like domain Nup160 PF11715.8 KXG48792.1 - 0.018 13.7 0.7 3.3 6.3 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 F-box_4 PF15966.5 KXG48792.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 F-box EB1 PF03271.17 KXG48793.1 - 1.1e-16 60.8 1.1 2.2e-16 59.8 1.1 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KXG48793.1 - 2.6e-06 27.6 0.6 4.6e-06 26.8 0.6 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 KXG48793.1 - 0.019 13.5 0.0 0.029 12.9 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like CH_2 PF06294.11 KXG48793.1 - 0.028 14.5 0.3 0.047 13.8 0.3 1.4 1 0 0 1 1 1 0 CH-like domain in sperm protein FTCD_C PF04961.12 KXG48793.1 - 0.052 13.3 0.1 0.078 12.7 0.1 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Adeno_E3_CR2 PF02439.15 KXG48794.1 - 0.01 15.6 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Cation_ATPase_C PF00689.21 KXG48795.1 - 2.5e-48 164.2 7.9 8.7e-48 162.4 7.9 2.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXG48795.1 - 7.2e-38 129.9 0.1 7.2e-38 129.9 0.1 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXG48795.1 - 6.9e-20 70.9 0.0 1.3e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXG48795.1 - 2.8e-18 67.0 0.3 7.2e-18 65.6 0.3 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXG48795.1 - 7.5e-08 32.0 0.1 4.9e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXG48795.1 - 4.8e-05 23.2 0.0 0.0027 17.5 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Antimicrobial_3 PF08025.11 KXG48795.1 - 0.021 14.7 0.6 0.084 12.8 0.6 2.0 1 0 0 1 1 1 0 Spider antimicrobial peptide DUF1774 PF08611.10 KXG48795.1 - 0.094 13.0 6.2 0.2 12.0 0.1 2.9 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) P16-Arc PF04699.14 KXG48796.1 - 1.3e-45 155.5 0.0 1.5e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Herpes_TAF50 PF03326.13 KXG48796.1 - 0.12 11.0 0.2 0.18 10.4 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) PAS_4 PF08448.10 KXG48796.1 - 0.13 12.5 0.1 0.39 11.0 0.0 1.8 2 0 0 2 2 2 0 PAS fold Methyltransf_11 PF08241.12 KXG48797.1 - 2.5e-11 44.0 0.0 5.6e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG48797.1 - 4.6e-09 36.3 0.0 7.6e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG48797.1 - 2.5e-07 31.3 0.0 7.5e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG48797.1 - 3.6e-06 27.6 0.0 6.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG48797.1 - 0.00066 19.5 0.0 0.0018 18.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Dynactin_p62 PF05502.13 KXG48798.1 - 1.3e-191 637.5 0.8 1.3e-191 637.5 0.0 1.3 2 0 0 2 2 2 1 Dynactin p62 family Mu-like_Com PF10122.9 KXG48798.1 - 2.5 7.6 5.6 2.9 7.4 0.8 2.8 2 0 0 2 2 2 0 Mu-like prophage protein Com Pox_Ag35 PF03286.14 KXG48798.1 - 2.9 7.6 5.6 8.1 6.2 5.6 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Trm112p PF03966.16 KXG48798.1 - 5.4 7.7 6.7 19 5.9 0.4 3.4 3 1 0 3 3 3 0 Trm112p-like protein Ribosomal_S7e PF01251.18 KXG48799.1 - 2e-82 275.4 0.2 3e-82 274.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S7e Ras PF00071.22 KXG48799.1 - 5.5e-56 188.6 0.0 2.2e-55 186.7 0.0 1.9 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KXG48799.1 - 4.4e-34 117.3 0.0 1e-33 116.1 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG48799.1 - 6.1e-14 51.8 0.0 1.3e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXG48799.1 - 2.6e-05 23.9 0.0 8.5e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXG48799.1 - 0.00013 21.5 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXG48799.1 - 0.00025 21.1 0.0 0.00062 19.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXG48799.1 - 0.00094 19.6 0.4 0.0028 18.1 0.1 2.0 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXG48799.1 - 0.11 12.8 0.1 9 6.6 0.0 3.1 2 1 1 3 3 3 0 AAA domain Acetate_kinase PF00871.17 KXG48800.1 - 1.3e-88 297.4 0.0 1.5e-88 297.1 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family XFP_N PF09364.10 KXG48801.1 - 1.3e-148 494.7 0.0 1.7e-148 494.3 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 KXG48801.1 - 4.2e-80 268.0 0.0 6.4e-80 267.4 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 KXG48801.1 - 1.6e-74 249.4 0.0 2.5e-74 248.8 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 KXG48801.1 - 0.021 14.6 0.1 0.046 13.5 0.1 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain RTA1 PF04479.13 KXG48802.1 - 4.2e-73 245.4 12.6 6e-73 244.8 12.6 1.2 1 0 0 1 1 1 1 RTA1 like protein AAA_16 PF13191.6 KXG48803.1 - 9.3e-06 26.1 0.0 3.2e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KXG48803.1 - 0.013 15.5 0.0 0.036 14.0 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF2193 PF09959.9 KXG48803.1 - 0.017 13.6 0.0 0.027 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) AAA_7 PF12775.7 KXG48803.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region nsp7 PF08716.10 KXG48803.1 - 0.056 14.1 0.0 0.27 11.9 0.0 2.1 2 0 0 2 2 2 0 nsp7 replicase AAA_5 PF07728.14 KXG48803.1 - 0.11 12.5 0.1 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXG48803.1 - 0.18 11.1 0.3 0.48 9.8 0.1 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI CLU PF13236.6 KXG48804.1 - 9.4e-75 251.2 0.0 1.7e-74 250.3 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KXG48804.1 - 5.7e-54 182.8 0.1 2e-53 181.0 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KXG48804.1 - 3.1e-26 91.5 6.1 7e-13 48.7 0.1 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 KXG48804.1 - 3.4e-25 88.2 0.1 1.1e-24 86.5 0.1 2.0 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 KXG48804.1 - 1.7e-22 78.6 0.6 1.5e-06 27.8 0.0 5.3 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXG48804.1 - 0.064 13.4 17.2 0.38 11.0 0.2 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXG48804.1 - 0.44 10.9 15.0 0.069 13.4 0.7 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXG48804.1 - 5.1 7.7 5.4 3.2e+02 2.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat NAD_binding_6 PF08030.12 KXG48806.1 - 1.5e-19 70.6 0.0 3.2e-17 63.1 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KXG48806.1 - 2.1e-18 66.6 9.8 2.1e-18 66.6 9.8 2.7 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXG48806.1 - 1.5e-14 54.0 0.0 6.9e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain Tannase PF07519.11 KXG48807.1 - 8.3e-91 305.2 4.9 1e-90 305.0 4.9 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase RTA1 PF04479.13 KXG48807.1 - 1.6e-58 197.7 10.3 1.6e-58 197.7 10.3 1.7 1 1 1 2 2 2 1 RTA1 like protein Hydrolase_4 PF12146.8 KXG48807.1 - 1e-06 28.2 0.0 0.0022 17.3 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXG48807.1 - 5.5e-05 22.7 0.2 0.14 11.6 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KXG48807.1 - 0.00022 21.0 0.6 0.00052 19.7 0.6 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXG48807.1 - 0.091 12.4 1.0 0.24 11.0 1.0 1.8 1 1 0 1 1 1 0 Putative esterase GST_N PF02798.20 KXG48808.1 - 3.4e-16 59.3 0.0 6.6e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXG48808.1 - 5.9e-15 55.4 0.0 1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXG48808.1 - 8.8e-13 48.4 0.0 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXG48808.1 - 3.9e-11 43.0 0.0 8.9e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXG48808.1 - 2e-10 40.8 0.0 3.6e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXG48808.1 - 4.2e-07 29.9 0.0 7.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SF1-HH PF16275.5 KXG48809.1 - 4.6e-43 146.1 1.5 4.6e-43 146.1 1.5 2.0 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KXG48809.1 - 7.2e-12 44.8 11.1 1.4e-05 25.0 0.8 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KXG48809.1 - 7e-08 32.2 0.1 1.3e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 KXG48809.1 - 1.1e-06 28.5 5.4 0.0014 18.5 2.9 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KXG48809.1 - 0.00072 19.3 6.3 0.32 10.9 0.5 3.1 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KXG48809.1 - 0.0016 18.2 5.0 0.44 10.3 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 KXG48809.1 - 0.015 15.1 0.5 0.015 15.1 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle HCO3_cotransp PF00955.21 KXG48810.1 - 3.8e-84 283.4 12.2 4.1e-46 157.9 6.1 2.1 1 1 1 2 2 2 2 HCO3- transporter family DEAD PF00270.29 KXG48811.1 - 5.5e-42 143.5 0.0 1.4e-41 142.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG48811.1 - 4.7e-31 107.4 0.0 1.6e-30 105.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG48811.1 - 1.6e-07 31.5 0.0 3.5e-07 30.4 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KXG48811.1 - 0.00097 17.9 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 KXG48811.1 - 0.044 13.4 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase SPAN-X PF07458.12 KXG48812.1 - 0.033 14.6 0.1 0.097 13.1 0.1 1.8 1 0 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome PRCC PF10253.9 KXG48812.1 - 3.9 8.2 10.7 0.24 12.2 5.2 1.7 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting DUF1793 PF08760.11 KXG48813.1 - 1.6e-70 236.8 0.5 1.6e-70 236.8 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KXG48813.1 - 1.8e-62 210.1 1.1 6.7e-49 165.9 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KXG48813.1 - 1.1e-50 172.5 0.6 1.9e-50 171.8 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KXG48813.1 - 0.0031 17.0 0.1 0.0073 15.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Stm1_N PF09598.10 KXG48814.1 - 2.6e-16 60.2 5.9 2.6e-16 60.2 5.9 5.2 2 2 1 3 3 3 1 Stm1 Epimerase PF01370.21 KXG48815.1 - 1.3e-12 47.7 1.5 5.8e-10 39.0 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXG48815.1 - 4.5e-10 39.7 0.2 7.1e-10 39.1 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KXG48815.1 - 1.3e-08 34.3 0.1 2.8e-07 29.9 0.1 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KXG48815.1 - 7.7e-08 32.2 0.2 1.3e-07 31.5 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KXG48815.1 - 0.00019 20.9 0.4 0.00035 20.1 0.1 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXG48815.1 - 0.0004 19.6 0.3 0.00076 18.7 0.2 1.5 2 0 0 2 2 2 1 Male sterility protein TrkA_N PF02254.18 KXG48815.1 - 0.00043 20.5 0.0 0.00095 19.4 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 KXG48815.1 - 0.001 18.2 0.1 0.0025 16.9 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KXG48815.1 - 0.0012 18.4 0.2 0.0018 17.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KXG48815.1 - 0.015 15.5 0.1 0.037 14.3 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KXG48815.1 - 0.078 12.6 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA APH PF01636.23 KXG48816.1 - 0.016 15.1 0.1 0.025 14.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family bZIP_1 PF00170.21 KXG48817.1 - 4e-05 23.6 9.5 7.9e-05 22.7 9.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXG48817.1 - 0.015 15.3 9.8 0.015 15.3 9.8 2.0 2 0 0 2 2 2 0 Basic region leucine zipper GvpL_GvpF PF06386.11 KXG48817.1 - 0.25 11.3 2.8 0.41 10.5 2.8 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4407 PF14362.6 KXG48817.1 - 0.27 10.5 3.9 3.1 7.1 3.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pex19 PF04614.12 KXG48818.1 - 1.6e-75 254.1 5.5 2.4e-75 253.5 5.5 1.3 1 0 0 1 1 1 1 Pex19 protein family Pup PF05639.11 KXG48818.1 - 0.065 14.1 1.6 0.13 13.1 0.3 2.2 2 0 0 2 2 2 0 Pup-like protein MRI PF15325.6 KXG48818.1 - 7.5 7.7 13.2 4.5 8.4 1.0 2.9 2 1 1 3 3 3 0 Modulator of retrovirus infection Pkinase PF00069.25 KXG48820.1 - 5.7e-07 29.2 0.0 1.2e-06 28.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48820.1 - 5.9e-07 29.0 0.0 4.7e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KXG48820.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_IclR PF09339.10 KXG48820.1 - 0.14 12.0 0.2 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain Mid2 PF04478.12 KXG48821.1 - 2.9e-07 30.4 1.4 2.9e-07 30.4 1.4 2.7 2 2 1 3 3 3 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 KXG48821.1 - 0.013 14.9 1.3 0.054 12.9 1.3 2.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SPX PF03105.19 KXG48821.1 - 0.016 15.1 10.3 0.017 15.0 10.3 1.2 1 0 0 1 1 1 0 SPX domain Endomucin PF07010.12 KXG48821.1 - 0.06 13.3 39.4 0.07 13.1 39.4 1.1 1 0 0 1 1 1 0 Endomucin Utp14 PF04615.13 KXG48821.1 - 0.075 11.6 6.1 0.086 11.4 6.1 1.0 1 0 0 1 1 1 0 Utp14 protein Presenilin PF01080.17 KXG48821.1 - 0.2 10.4 4.4 0.28 9.9 4.4 1.3 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 KXG48821.1 - 0.27 9.7 8.8 0.33 9.5 8.8 1.1 1 0 0 1 1 1 0 Macoilin family FeoB_associated PF12669.7 KXG48821.1 - 0.39 11.2 4.0 1.4 9.4 4.0 1.8 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Dicty_REP PF05086.12 KXG48821.1 - 2.2 6.2 18.2 2.6 5.9 18.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mrx7 PF10906.8 KXG48823.1 - 6.1e-12 45.6 0.4 1e-11 44.9 0.4 1.4 1 1 0 1 1 1 1 MIOREX complex component 7 Fungal_trans_2 PF11951.8 KXG48824.1 - 1.2e-29 103.3 0.3 1.1e-28 100.2 0.3 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG48824.1 - 1.9e-06 27.9 8.0 3.2e-06 27.2 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NYAP_N PF15439.6 KXG48824.1 - 0.043 13.0 0.1 0.069 12.3 0.1 1.2 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Pkinase PF00069.25 KXG48825.1 - 4.3e-65 219.7 0.0 6e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48825.1 - 2.9e-31 108.7 0.0 4.7e-30 104.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXG48825.1 - 0.002 17.5 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXG48825.1 - 0.0068 15.4 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KXG48825.1 - 0.01 15.5 0.1 0.57 9.8 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KXG48825.1 - 0.022 14.7 0.0 0.063 13.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KXG48825.1 - 0.03 13.7 0.2 0.17 11.1 0.0 2.2 2 1 0 2 2 2 0 Kinase-like ANAPC_CDC26 PF10471.9 KXG48826.1 - 0.00024 21.9 0.7 0.00042 21.1 0.6 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 NAD_binding_8 PF13450.6 KXG48827.1 - 6e-08 32.8 0.0 1.5e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXG48827.1 - 4.2e-05 23.0 0.0 6.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KXG48827.1 - 0.0027 17.0 0.4 0.011 14.9 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG48827.1 - 0.0045 16.3 0.2 0.0074 15.6 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXG48827.1 - 0.005 16.2 0.0 0.0072 15.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXG48827.1 - 0.0085 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXG48827.1 - 0.012 14.9 0.1 0.023 13.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KXG48827.1 - 0.045 13.3 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXG48827.1 - 0.061 12.4 0.1 0.15 11.1 0.1 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 KXG48827.1 - 0.092 11.4 0.1 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 KXG48827.1 - 0.093 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain TPT PF03151.16 KXG48828.1 - 1.6e-25 90.1 27.5 2.1e-25 89.7 27.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXG48828.1 - 0.044 13.0 27.5 0.18 11.0 27.5 2.0 1 1 0 1 1 1 0 UAA transporter family Glu_cys_ligase PF04262.14 KXG48830.1 - 0.035 12.7 0.4 0.048 12.3 0.4 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase DUF1515 PF07439.11 KXG48830.1 - 0.08 13.0 3.3 0.24 11.4 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) CENP-F_leu_zip PF10473.9 KXG48830.1 - 0.14 12.2 8.3 0.22 11.5 8.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YPEB PF14620.6 KXG48830.1 - 0.14 11.5 2.6 0.21 10.9 2.6 1.3 1 0 0 1 1 1 0 YpeB sporulation CCDC92 PF14916.6 KXG48830.1 - 0.48 10.2 4.0 23 4.8 0.0 3.0 3 0 0 3 3 3 0 Coiled-coil domain of unknown function Allexi_40kDa PF05549.11 KXG48830.1 - 0.64 9.5 5.3 1.4 8.4 5.3 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein Syntaxin-6_N PF09177.11 KXG48830.1 - 0.71 10.5 6.6 1.5 9.4 4.8 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal GAS PF13851.6 KXG48830.1 - 0.94 8.8 9.6 3 7.2 9.6 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF848 PF05852.11 KXG48830.1 - 1.7 8.8 7.3 4.6 7.3 6.5 2.0 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) FlxA PF14282.6 KXG48830.1 - 1.9 8.6 8.3 6.3 6.9 6.5 2.2 1 1 1 2 2 2 0 FlxA-like protein APG6_N PF17675.1 KXG48830.1 - 3.5 8.2 11.4 3.7 8.1 9.9 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region Wbp11 PF09429.10 KXG48830.1 - 5.1 7.6 11.5 9.6 6.7 0.2 2.5 2 1 0 2 2 2 0 WW domain binding protein 11 FAM76 PF16046.5 KXG48830.1 - 5.9 6.1 9.5 5.7 6.2 0.2 2.1 1 1 1 2 2 2 0 FAM76 protein TFIIB PF00382.19 KXG48831.1 - 3.7e-32 110.2 0.3 1.9e-16 59.8 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KXG48831.1 - 5.1e-27 94.2 0.4 5.2e-26 90.9 0.0 2.8 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KXG48831.1 - 0.00028 20.4 2.3 0.00072 19.0 2.3 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KXG48831.1 - 0.00064 19.5 0.1 0.96 9.2 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain IBR PF01485.21 KXG48831.1 - 0.15 12.3 0.7 0.3 11.3 0.7 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain GP67 PF17634.2 KXG48831.1 - 0.15 12.5 15.1 0.34 11.3 15.1 1.6 1 0 0 1 1 1 0 Gene product 67 E1-E2_ATPase PF00122.20 KXG48832.1 - 1.6e-49 167.9 0.3 1.4e-48 164.8 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 KXG48832.1 - 3.3e-48 162.0 0.8 8.5e-15 55.0 0.0 4.8 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KXG48832.1 - 1.3e-35 123.6 0.3 2.4e-35 122.7 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXG48832.1 - 9.3e-07 28.8 1.5 0.001 18.9 0.5 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXG48832.1 - 0.002 18.5 0.0 0.008 16.6 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CmcI PF04989.12 KXG48832.1 - 0.012 15.3 1.2 0.061 13.0 0.1 2.7 4 0 0 4 4 4 0 Cephalosporin hydroxylase Fer2_BFD PF04324.15 KXG48832.1 - 0.099 13.0 0.1 37 4.8 0.0 3.9 3 0 0 3 3 3 0 BFD-like [2Fe-2S] binding domain ERCC4 PF02732.15 KXG48833.1 - 4.4e-25 88.7 0.0 7.1e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain DUF3669 PF12417.8 KXG48834.1 - 7.3e-21 74.2 0.3 2e-20 72.7 0.3 1.8 1 0 0 1 1 1 1 Zinc finger protein DUF2252 PF10009.9 KXG48834.1 - 0.086 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Epimerase PF01370.21 KXG48835.1 - 7.8e-20 71.4 0.0 8.8e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG48835.1 - 6.7e-14 52.0 0.0 2.2e-13 50.3 0.0 1.7 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXG48835.1 - 9.2e-12 44.5 0.0 1.1e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXG48835.1 - 2.7e-06 26.7 0.0 5.1e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXG48835.1 - 5.2e-06 25.8 0.1 0.077 12.2 0.0 2.7 2 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KXG48835.1 - 5.9e-05 23.0 0.0 8.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KXG48835.1 - 0.0097 15.8 0.0 0.77 9.6 0.0 2.3 1 1 1 2 2 2 1 KR domain Ldh_1_N PF00056.23 KXG48835.1 - 0.014 15.5 0.0 0.036 14.2 0.0 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KXG48835.1 - 0.029 13.5 0.0 0.22 10.6 0.0 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 KXG48835.1 - 0.036 13.5 0.0 0.081 12.4 0.0 1.7 1 1 0 1 1 1 0 short chain dehydrogenase Fungal_trans PF04082.18 KXG48836.1 - 8.4e-07 28.3 0.3 1.7e-06 27.2 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG48836.1 - 7.7e-06 25.9 10.8 1.3e-05 25.2 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LKAAEAR PF15478.6 KXG48837.1 - 1.9 8.8 7.8 1.4 9.2 6.4 1.5 1 1 1 2 2 2 0 Family of unknown function with LKAAEAR motif ChAPs PF09295.10 KXG48838.1 - 1.8e-155 517.8 0.0 2.3e-155 517.5 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 KXG48838.1 - 6.2e-05 23.5 1.2 0.13 13.2 0.1 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXG48838.1 - 9.9e-05 22.0 0.1 1.9 8.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXG48838.1 - 0.00017 21.4 0.8 0.22 11.8 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXG48838.1 - 0.0004 20.8 0.1 1.4 9.5 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 KXG48838.1 - 0.00052 19.3 1.4 0.15 11.3 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXG48838.1 - 0.0034 17.6 0.1 3.5 8.0 0.1 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXG48838.1 - 0.0035 17.2 0.5 6.7 7.0 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXG48838.1 - 0.0049 17.0 0.1 4.4 7.8 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXG48838.1 - 0.068 13.3 0.2 2.2 8.5 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXG48839.1 - 0.19 12.3 1.5 51 4.5 0.9 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXG48839.1 - 0.33 10.7 2.2 1 9.1 2.2 1.9 1 0 0 1 1 1 0 TPR repeat Kinesin PF00225.23 KXG48840.1 - 6.8e-59 199.4 0.0 1.1e-58 198.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXG48840.1 - 4.8e-12 46.0 0.0 6.9e-10 39.0 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding bZIP_2 PF07716.15 KXG48840.1 - 0.0026 17.8 3.0 0.0075 16.3 3.0 1.8 1 0 0 1 1 1 1 Basic region leucine zipper DUF2277 PF10041.9 KXG48840.1 - 0.094 13.1 0.0 0.4 11.1 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) EzrA PF06160.12 KXG48840.1 - 0.75 7.9 6.8 7.1 4.7 0.5 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Stathmin PF00836.19 KXG48840.1 - 4.3 7.3 12.4 1.2 9.2 8.7 1.9 1 1 0 1 1 1 0 Stathmin family DUF87 PF01935.17 KXG48840.1 - 5.6 7.0 7.4 5.9 6.9 0.5 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain RTA1 PF04479.13 KXG48841.1 - 3.7e-39 134.5 7.8 5e-39 134.1 7.8 1.2 1 0 0 1 1 1 1 RTA1 like protein tRNA-synt_2b PF00587.25 KXG48842.1 - 7e-21 75.0 0.0 1e-20 74.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KXG48842.1 - 8.4e-10 38.9 2.9 4.2e-09 36.6 2.9 1.9 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain GOLGA2L5 PF15070.6 KXG48842.1 - 1.1e-05 24.3 0.8 1.6e-05 23.8 0.8 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 CENP-F_leu_zip PF10473.9 KXG48842.1 - 0.015 15.3 1.9 0.29 11.2 0.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 KXG48842.1 - 0.019 14.7 2.1 0.91 9.3 0.2 2.4 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 KXG48842.1 - 0.02 15.3 0.2 5.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 KXG48842.1 - 0.24 11.5 0.2 0.24 11.5 0.2 2.7 3 0 0 3 3 2 0 bZIP transcription factor LPP PF04728.13 KXG48842.1 - 0.31 11.5 1.9 11 6.5 0.3 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF4200 PF13863.6 KXG48842.1 - 1.1 9.6 4.2 3.5 8.1 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Csm1_N PF18504.1 KXG48842.1 - 1.4 9.3 6.6 2.6 8.5 0.5 2.7 1 1 1 2 2 2 0 Csm1 N-terminal domain JIP_LZII PF16471.5 KXG48842.1 - 1.9 8.8 7.2 16 5.7 1.5 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Spc7 PF08317.11 KXG48842.1 - 1.9 7.3 6.9 6.3 5.6 7.1 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 KXG48842.1 - 2.2 7.6 5.3 0.92 8.8 2.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Swi5 PF07061.11 KXG48842.1 - 2.7 8.2 4.4 19 5.4 0.4 2.5 2 0 0 2 2 2 0 Swi5 PI3K_P85_iSH2 PF16454.5 KXG48842.1 - 8.3 6.0 7.1 2.6 7.6 1.0 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TMF_DNA_bd PF12329.8 KXG48842.1 - 9.4 6.3 8.8 27 4.9 7.4 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding BTB PF00651.31 KXG48843.1 - 0.0012 19.0 0.0 0.019 15.2 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Y_phosphatase PF00102.27 KXG48844.1 - 8.4e-52 176.1 0.0 1.1e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KXG48844.1 - 0.0043 17.0 0.0 0.0075 16.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KXG48844.1 - 0.0055 16.8 0.0 0.016 15.3 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.20 KXG48844.1 - 0.021 14.7 1.5 0.11 12.3 1.4 2.0 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain VanZ PF04892.12 KXG48845.1 - 2e-06 28.5 2.5 3.4e-06 27.7 2.5 1.3 1 1 0 1 1 1 1 VanZ like family DUF2842 PF11003.8 KXG48845.1 - 0.031 14.5 0.3 0.059 13.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2842) Phage_holin_2_4 PF16082.5 KXG48845.1 - 0.046 13.4 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Bromodomain PF00439.25 KXG48846.1 - 4.4e-17 61.9 0.0 1e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 KXG48846.1 - 2.1e-09 37.2 0.0 7.4e-09 35.5 0.0 1.9 1 0 0 1 1 1 1 Bromodomain associated Talin_middle PF09141.10 KXG48846.1 - 0.066 13.2 0.2 0.3 11.1 0.2 2.1 2 0 0 2 2 2 0 Talin, middle domain PBP1_TM PF14812.6 KXG48846.1 - 0.17 12.3 13.9 0.13 12.7 7.5 3.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Piwi PF02171.17 KXG48847.1 - 2.3e-60 204.4 0.0 4.1e-60 203.6 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KXG48847.1 - 9.5e-13 49.0 0.0 3.8e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KXG48847.1 - 3.7e-12 45.7 0.1 1.8e-11 43.5 0.0 2.2 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 KXG48847.1 - 6.7e-11 42.1 0.3 1.6e-10 40.9 0.3 1.6 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KXG48847.1 - 3e-08 33.9 0.0 7.8e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KXG48847.1 - 6.9e-08 32.6 0.0 1.9e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute DUF2397 PF09660.10 KXG48847.1 - 0.049 12.5 5.1 0.085 11.7 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) tRNA_synt_1c_R1 PF04558.15 KXG48848.1 - 0.067 13.2 0.4 0.089 12.8 0.4 1.1 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Suf PF05843.14 KXG48849.1 - 7.8e-90 301.8 0.1 7.8e-90 301.8 0.1 4.2 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KXG48849.1 - 0.0011 19.6 0.6 1.6 9.7 0.4 4.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXG48849.1 - 0.0084 16.7 0.0 0.059 14.0 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat HAT PF02184.16 KXG48849.1 - 0.025 14.5 0.0 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat ASF1_hist_chap PF04729.13 KXG48850.1 - 3.2e-72 241.5 0.0 4.2e-72 241.1 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.12 KXG48850.1 - 0.0075 14.6 23.8 0.0099 14.2 23.8 1.0 1 0 0 1 1 1 1 Nop14-like family Lgl_C PF08596.10 KXG48851.1 - 7.3e-131 436.5 0.0 4.9e-130 433.7 0.0 2.0 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KXG48851.1 - 6e-06 26.9 4.5 0.13 13.2 0.2 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG48851.1 - 6.7e-06 26.3 0.0 0.41 11.0 0.0 4.8 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M23 PF01551.22 KXG48851.1 - 0.023 14.9 0.0 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M23 Nup160 PF11715.8 KXG48851.1 - 0.12 11.0 0.0 6.7 5.2 0.0 2.6 3 0 0 3 3 3 0 Nucleoporin Nup120/160 APH PF01636.23 KXG48852.1 - 1.9e-06 28.0 0.1 3.4e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family THUMP PF02926.17 KXG48853.1 - 4.6e-12 46.2 0.0 1.2e-11 44.9 0.0 1.6 2 0 0 2 2 2 1 THUMP domain TPP_enzyme_N PF02776.18 KXG48854.1 - 9.9e-33 113.2 0.0 1.6e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXG48854.1 - 1.8e-24 86.0 0.0 3.3e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KXG48854.1 - 2.8e-14 53.2 0.0 6.6e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MFS_1 PF07690.16 KXG48855.1 - 4e-22 78.6 58.0 7e-14 51.5 37.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2976 PF11190.8 KXG48855.1 - 0.28 11.0 8.3 0.21 11.4 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) Pkinase PF00069.25 KXG48856.1 - 1e-60 205.3 0.0 1.8e-60 204.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48856.1 - 5.2e-43 147.2 0.0 7.9e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG48856.1 - 5.6e-08 32.4 0.0 8.3e-07 28.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXG48856.1 - 0.0017 17.3 0.0 0.0052 15.6 0.0 1.8 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXG48856.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXG48856.1 - 0.02 14.8 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sec34 PF04136.15 KXG48857.1 - 7.9e-50 168.6 1.6 1.5e-49 167.7 1.6 1.5 1 0 0 1 1 1 1 Sec34-like family HeLo PF14479.6 KXG48857.1 - 0.14 12.0 0.8 0.52 10.1 0.7 2.0 1 1 0 1 1 1 0 Prion-inhibition and propagation RCC1 PF00415.18 KXG48858.1 - 7.7e-33 112.9 0.5 3.6e-06 27.5 0.0 6.9 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXG48858.1 - 1.3e-18 66.3 14.8 1.4e-11 43.9 0.1 6.6 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 KXG48858.1 - 0.014 15.2 0.0 0.33 10.8 0.0 2.7 3 0 0 3 3 3 0 Peptidase family C25, C terminal ig-like domain PUF PF00806.19 KXG48859.1 - 1.8e-15 55.7 0.0 0.37 10.6 0.0 7.7 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat Pyridoxal_deC PF00282.19 KXG48860.1 - 1.2e-80 271.0 0.0 1.1e-79 267.9 0.0 2.3 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KXG48860.1 - 2.1e-05 24.0 0.0 3.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KXG48860.1 - 3.7e-05 22.9 0.0 6.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V SepSecS PF05889.13 KXG48860.1 - 0.16 10.6 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS RINT1_TIP1 PF04437.13 KXG48861.1 - 1.3e-181 604.9 2.1 2e-181 604.3 0.1 2.0 2 0 0 2 2 2 1 RINT-1 / TIP-1 family CRISPR_Cse2 PF09485.10 KXG48861.1 - 1.3 9.5 8.5 2.9 8.4 6.3 2.7 1 1 1 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DNA_ligase_A_M PF01068.21 KXG48862.1 - 1.2e-53 181.8 0.1 9.1e-51 172.4 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXG48862.1 - 2.5e-38 132.1 0.0 5.1e-38 131.1 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KXG48862.1 - 2.7e-19 69.6 0.0 8.7e-19 68.0 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KXG48862.1 - 0.00028 21.2 0.0 0.00053 20.3 0.0 1.4 1 0 0 1 1 1 1 RNA ligase Whi5 PF08528.11 KXG48863.1 - 0.0069 16.0 0.4 0.014 15.0 0.4 1.5 1 0 0 1 1 1 1 Whi5 like Metallopep PF12044.8 KXG48864.1 - 2.9e-173 576.4 0.0 3.6e-173 576.1 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.6 KXG48864.1 - 0.036 14.2 0.3 0.067 13.3 0.3 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KXG48864.1 - 0.11 13.0 0.5 0.25 11.9 0.5 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CP2 PF04516.15 KXG48865.1 - 1.8e-81 272.8 0.0 3.1e-81 272.1 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor TAF PF02969.17 KXG48867.1 - 0.12 12.6 1.5 89 3.4 0.0 3.2 3 0 0 3 3 3 0 TATA box binding protein associated factor (TAF) DUF3328 PF11807.8 KXG48868.1 - 3.3e-26 92.4 0.0 7.3e-26 91.3 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Tetraspanin PF00335.20 KXG48868.1 - 0.18 11.5 0.6 8.7 6.0 0.0 2.0 2 0 0 2 2 2 0 Tetraspanin family DUF3357 PF11837.8 KXG48869.1 - 0.028 14.9 0.0 0.039 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) ABC_tran PF00005.27 KXG48870.1 - 1.3e-37 129.4 0.0 2.8e-21 76.5 0.1 2.7 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXG48870.1 - 3.3e-32 112.2 35.8 2.2e-20 73.5 16.3 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KXG48870.1 - 1.7e-08 34.2 1.9 0.41 10.1 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KXG48870.1 - 1.5e-07 31.5 0.0 0.00088 19.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KXG48870.1 - 3.1e-06 27.2 3.2 0.35 10.6 0.0 4.1 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXG48870.1 - 5e-06 26.2 1.7 0.033 13.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 KXG48870.1 - 3.1e-05 24.0 1.5 0.0089 16.0 0.0 3.0 3 0 0 3 3 2 1 NACHT domain Viral_helicase1 PF01443.18 KXG48870.1 - 4e-05 23.5 0.1 0.0092 15.7 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 KXG48870.1 - 7.1e-05 23.4 0.7 0.51 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 KXG48870.1 - 0.00015 21.2 2.4 0.11 11.9 0.1 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.6 KXG48870.1 - 0.00023 21.5 0.6 0.81 10.0 0.0 3.4 3 1 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 KXG48870.1 - 0.00035 20.5 1.2 0.59 10.0 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXG48870.1 - 0.00071 20.0 1.3 0.93 9.9 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 KXG48870.1 - 0.00073 18.7 0.4 0.43 9.6 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.6 KXG48870.1 - 0.00074 19.1 0.3 0.54 9.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 KXG48870.1 - 0.00078 19.5 0.9 0.34 11.0 0.1 2.3 2 0 0 2 2 2 1 Dynamin family cobW PF02492.19 KXG48870.1 - 0.00099 18.7 2.1 0.18 11.4 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.15 KXG48870.1 - 0.0013 17.6 0.8 0.81 8.4 0.1 2.3 2 0 0 2 2 2 2 Adenovirus IVa2 protein DUF87 PF01935.17 KXG48870.1 - 0.0017 18.5 4.2 0.011 15.9 0.5 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_33 PF13671.6 KXG48870.1 - 0.0025 18.0 0.1 3.1 7.9 0.1 2.7 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KXG48870.1 - 0.0032 17.4 0.2 0.25 11.2 0.0 2.7 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KXG48870.1 - 0.0048 16.1 0.3 4.3 6.4 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain AAA_18 PF13238.6 KXG48870.1 - 0.012 16.2 1.1 5 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXG48870.1 - 0.015 14.5 0.1 5.9 6.1 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 KXG48870.1 - 0.016 15.6 0.1 5 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 KXG48870.1 - 0.017 15.1 0.3 0.65 10.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 KXG48870.1 - 0.022 14.0 0.0 2.6 7.2 0.0 3.1 3 0 0 3 3 3 0 KAP family P-loop domain DUF815 PF05673.13 KXG48870.1 - 0.028 13.6 0.3 5.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MeaB PF03308.16 KXG48870.1 - 0.046 12.7 0.5 2.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SbcCD_C PF13558.6 KXG48870.1 - 0.047 13.9 0.1 3.1 8.1 0.0 3.1 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 KXG48870.1 - 0.055 13.2 0.4 0.38 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 KXG48870.1 - 0.059 12.3 1.8 4.7 6.0 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.17 KXG48870.1 - 0.067 13.0 0.2 11 5.7 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 KXG48870.1 - 0.11 12.0 0.1 8 5.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 KXG48870.1 - 0.11 12.0 0.5 17 4.9 0.1 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DEAD PF00270.29 KXG48870.1 - 0.15 11.9 0.1 6.2 6.5 0.0 2.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_30 PF13604.6 KXG48870.1 - 0.18 11.5 1.7 1.8 8.3 0.1 2.5 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 KXG48870.1 - 0.18 11.8 0.4 27 4.8 0.1 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 KXG48870.1 - 0.27 10.9 0.3 20 4.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DAP3 PF10236.9 KXG48870.1 - 0.34 10.1 1.2 7.3 5.6 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.9 KXG48870.1 - 0.7 9.1 2.1 13 4.9 0.3 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Clathrin PF00637.20 KXG48871.1 - 2.3e-19 69.7 0.1 9e-19 67.8 0.1 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_1 PF10366.9 KXG48871.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 WD40_like PF17005.5 KXG48871.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain zf-RING_5 PF14634.6 KXG48871.1 - 0.25 11.4 0.3 0.48 10.4 0.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain CENP-B_dimeris PF09026.10 KXG48871.1 - 0.28 11.6 9.5 0.79 10.1 9.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PQQ_3 PF13570.6 KXG48871.1 - 0.52 10.9 2.4 2.5 8.7 0.2 3.0 3 0 0 3 3 3 0 PQQ-like domain DUF155 PF02582.14 KXG48872.1 - 1.7e-47 161.8 0.0 5e-47 160.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Ribonuclease_T2 PF00445.18 KXG48873.1 - 2e-43 148.7 0.2 3.1e-43 148.1 0.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family zf-H2C2_2 PF13465.6 KXG48874.1 - 3e-08 33.7 3.6 0.0046 17.3 0.6 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXG48874.1 - 2.5e-06 27.6 17.6 0.0035 17.7 4.5 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KXG48874.1 - 4.9e-06 26.4 4.8 0.019 14.9 3.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KXG48874.1 - 1.2e-05 25.7 16.1 0.0027 18.4 3.6 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXG48874.1 - 0.0035 17.6 2.3 0.0035 17.6 2.3 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KXG48874.1 - 0.55 10.7 3.2 1.7 9.2 3.2 1.9 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 KXG48874.1 - 1.2 9.2 4.9 0.9 9.6 2.1 2.1 1 1 1 2 2 2 0 BED zinc finger Ank_2 PF12796.7 KXG48875.1 - 1.4e-19 70.4 0.0 2.6e-08 34.3 0.0 3.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG48875.1 - 8.4e-19 67.7 1.1 7.3e-06 26.4 0.0 4.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG48875.1 - 5.1e-16 57.2 2.2 0.48 11.2 0.0 6.4 6 1 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KXG48875.1 - 6.4e-12 45.4 2.9 0.0089 16.4 0.1 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 KXG48875.1 - 1.8e-07 31.3 0.4 0.0069 16.7 0.1 4.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) ubiquitin PF00240.23 KXG48876.1 - 4.3e-34 116.1 0.6 7.9e-34 115.2 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 KXG48876.1 - 1.2e-26 92.6 1.8 1.2e-26 92.6 1.8 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KXG48876.1 - 2.7e-16 59.2 0.7 4.9e-16 58.3 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXG48876.1 - 2.7e-05 24.5 0.4 0.00013 22.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXG48876.1 - 0.0013 18.8 0.6 0.0029 17.7 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KXG48876.1 - 0.0042 17.4 0.9 0.0079 16.5 0.0 1.8 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KXG48876.1 - 0.0054 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KXG48876.1 - 0.013 16.0 0.7 0.019 15.5 0.7 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KXG48876.1 - 0.021 14.9 1.0 5.9 7.0 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 KXG48876.1 - 0.028 14.6 0.2 0.048 13.9 0.2 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Glyco_hydro_18 PF00704.28 KXG48877.1 - 1.1e-88 298.0 0.1 1.2e-88 297.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Aldo_ket_red PF00248.21 KXG48878.1 - 8.8e-22 77.6 0.7 7e-07 28.7 0.0 3.0 1 1 1 3 3 3 3 Aldo/keto reductase family DUF1455 PF07306.11 KXG48879.1 - 0.022 14.7 0.3 0.093 12.7 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1455) DeoRC PF00455.22 KXG48879.1 - 0.059 13.3 0.1 0.077 12.9 0.1 1.3 1 0 0 1 1 1 0 DeoR C terminal sensor domain Proteasome PF00227.26 KXG48880.1 - 3.9e-50 170.0 0.0 5.5e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXG48880.1 - 5.8e-13 48.2 0.3 9.2e-13 47.6 0.3 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2373 PF10180.9 KXG48881.1 - 7.5e-21 73.7 0.3 1.4e-20 72.9 0.3 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) GCP_C_terminal PF04130.13 KXG48882.1 - 2e-103 346.1 0.1 3.1e-103 345.5 0.1 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KXG48882.1 - 2.6e-83 280.2 0.0 8.1e-83 278.5 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal K_channel_TID PF07941.11 KXG48882.1 - 0.5 10.9 3.1 1.6 9.2 3.1 1.9 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Fringe PF02434.16 KXG48883.1 - 1.2e-09 38.0 0.1 2.8e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 Fringe-like PAN_4 PF14295.6 KXG48883.1 - 0.00019 21.2 1.0 0.00047 20.0 1.0 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KXG48883.1 - 0.00092 19.1 0.1 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 PAN domain Citrate_bind PF16114.5 KXG48883.1 - 0.21 11.1 0.1 0.34 10.4 0.1 1.2 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding Aft1_HRA PF11786.8 KXG48884.1 - 2.8e-25 88.4 9.3 2.8e-25 88.4 9.3 2.4 2 0 0 2 2 2 1 Aft1 HRA domain Aft1_HRR PF11787.8 KXG48884.1 - 9.7e-21 74.7 5.3 9.7e-21 74.7 5.3 3.8 3 1 0 3 3 3 1 Aft1 HRR domain Aft1_OSA PF11785.8 KXG48884.1 - 4.3e-20 71.9 12.7 4.3e-20 71.9 12.7 3.5 3 2 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 KXG48884.1 - 6.5e-13 48.6 5.4 1.6e-12 47.3 5.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXG48884.1 - 6e-06 26.2 6.3 1.5e-05 25.0 6.3 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXG48884.1 - 0.012 16.2 4.1 0.012 16.2 4.1 2.6 1 1 1 2 2 2 0 bZIP Maf transcription factor Menin PF05053.13 KXG48884.1 - 1.1 7.5 12.8 1.6 7.0 12.8 1.1 1 0 0 1 1 1 0 Menin Transthyretin PF00576.21 KXG48885.1 - 4.6e-33 114.2 0.0 6.6e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 HIUase/Transthyretin family ArsA_ATPase PF02374.15 KXG48886.1 - 1.8e-114 382.0 0.1 2.1e-114 381.8 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KXG48886.1 - 2.3e-14 53.7 0.2 3.5e-13 49.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 KXG48886.1 - 3.5e-13 49.7 0.0 7.5e-13 48.6 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 KXG48886.1 - 2.2e-06 27.3 0.0 5.2e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 KXG48886.1 - 1.7e-05 24.4 2.9 0.00013 21.5 0.1 2.5 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 KXG48886.1 - 2.7e-05 23.9 1.1 0.00082 19.0 0.1 2.8 3 1 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 KXG48886.1 - 8.2e-05 22.2 0.1 0.00029 20.4 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ PhoH PF02562.16 KXG48886.1 - 0.018 14.5 0.1 0.053 13.0 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 KXG48886.1 - 0.037 13.6 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain A1_Propeptide PF07966.12 KXG48886.1 - 0.096 12.6 2.1 0.12 12.2 0.1 2.3 2 0 0 2 2 2 0 A1 Propeptide NB-ARC PF00931.22 KXG48886.1 - 0.13 11.5 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KXG48886.1 - 0.14 12.6 0.0 0.25 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain eIF3_N PF09440.10 KXG48888.1 - 5e-50 169.4 3.2 5.9e-50 169.2 1.9 1.8 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KXG48888.1 - 7e-14 52.2 0.1 2.5e-13 50.4 0.0 2.0 2 0 0 2 2 2 1 PCI domain Img2 PF05046.14 KXG48889.1 - 1.1e-25 89.8 0.0 1.7e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) GspL_C PF12693.7 KXG48889.1 - 0.03 14.2 1.1 0.14 12.0 1.4 1.9 1 1 1 2 2 2 0 GspL periplasmic domain DUF4554 PF15091.6 KXG48889.1 - 0.098 11.5 0.8 0.12 11.3 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) ARID PF01388.21 KXG48890.1 - 2.3e-19 69.8 0.0 7.2e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain AAA PF00004.29 KXG48891.1 - 2e-46 157.7 0.2 7.2e-46 155.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXG48891.1 - 1.2e-10 41.2 0.1 7.6e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KXG48891.1 - 5e-09 36.5 0.0 1e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXG48891.1 - 6.7e-09 35.9 0.6 2.2e-08 34.2 0.1 2.2 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXG48891.1 - 1.9e-07 31.6 0.6 3.5e-05 24.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KXG48891.1 - 2.3e-05 24.7 1.1 0.0055 17.0 0.1 2.7 1 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 KXG48891.1 - 6.4e-05 22.2 0.0 0.00012 21.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KXG48891.1 - 0.00021 21.3 0.0 0.00074 19.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 KXG48891.1 - 0.00024 20.9 0.1 0.00055 19.7 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KXG48891.1 - 0.0003 20.5 0.0 0.001 18.9 0.0 1.9 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KXG48891.1 - 0.00066 19.2 0.0 0.0061 16.1 0.1 2.3 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 KXG48891.1 - 0.0011 19.5 0.0 0.0034 17.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 KXG48891.1 - 0.0014 18.6 0.0 0.0048 16.8 0.0 1.9 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 KXG48891.1 - 0.0015 18.9 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 KXG48891.1 - 0.0017 18.5 0.0 0.0043 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KXG48891.1 - 0.0033 16.7 0.0 0.0066 15.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 KXG48891.1 - 0.0037 17.3 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KXG48891.1 - 0.0047 16.8 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXG48891.1 - 0.0053 16.7 0.3 0.11 12.4 0.0 2.9 3 0 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 KXG48891.1 - 0.0078 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KXG48891.1 - 0.0079 16.5 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KXG48891.1 - 0.0085 15.8 0.2 0.2 11.3 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 KXG48891.1 - 0.009 15.4 0.0 0.45 9.9 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein AAA_24 PF13479.6 KXG48891.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXG48891.1 - 0.013 15.3 0.1 0.033 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXG48891.1 - 0.013 15.3 0.1 0.045 13.5 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 KXG48891.1 - 0.044 13.7 1.2 0.41 10.5 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KXG48891.1 - 0.046 13.5 0.1 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 KXG48891.1 - 0.06 12.2 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase Bac_DnaA PF00308.18 KXG48891.1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase PF06745.13 KXG48891.1 - 0.076 12.3 0.9 0.91 8.8 0.0 2.4 3 0 0 3 3 2 0 KaiC AAA_25 PF13481.6 KXG48891.1 - 0.079 12.5 1.3 0.22 11.1 0.4 2.2 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KXG48891.1 - 0.083 12.2 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 KXG48891.1 - 0.092 13.2 0.2 2.3 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_Hsp90 PF03225.14 KXG48891.1 - 0.12 10.8 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AAA_19 PF13245.6 KXG48891.1 - 0.13 12.6 0.1 0.4 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXG48891.1 - 0.15 12.6 0.1 0.57 10.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KXG48891.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 KXG48891.1 - 0.2 10.7 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 FAD_binding_3 PF01494.19 KXG48892.1 - 4.1e-17 62.5 0.0 6e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG48892.1 - 3.5e-08 33.0 0.0 7.1e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG48892.1 - 1e-06 28.6 0.0 0.0046 16.6 0.1 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXG48892.1 - 1.3e-05 25.7 0.0 0.00014 22.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXG48892.1 - 0.00082 19.0 1.3 0.0027 17.4 0.1 2.3 2 1 1 3 3 3 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 KXG48892.1 - 0.002 18.3 0.1 0.0045 17.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXG48892.1 - 0.0026 16.9 0.1 0.0039 16.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KXG48892.1 - 0.0077 15.1 0.1 1.1 8.0 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase TrkA_N PF02254.18 KXG48892.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain TPMT PF05724.11 KXG48893.1 - 3.3e-29 102.1 0.0 5.1e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 KXG48893.1 - 3.8e-05 24.3 0.0 7.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG48893.1 - 0.00037 21.1 0.0 0.00062 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG48893.1 - 0.00076 19.4 0.0 0.0016 18.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG48893.1 - 0.0083 15.9 0.0 0.015 15.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain bZIP_1 PF00170.21 KXG48894.1 - 2.6e-06 27.4 1.4 4.8e-06 26.6 1.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor Asp PF00026.23 KXG48895.1 - 3.1e-109 365.2 0.0 3.7e-109 365.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXG48895.1 - 1.7e-16 60.9 1.1 2.5e-14 53.9 0.9 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXG48895.1 - 2.3e-05 24.9 0.4 0.17 12.6 0.0 3.4 3 2 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KXG48895.1 - 0.00017 22.1 0.0 0.89 10.2 0.0 3.5 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KXG48895.1 - 0.021 14.6 0.0 0.3 10.8 0.0 2.4 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal NIF PF03031.18 KXG48896.1 - 6.3e-29 100.8 0.4 1.2e-28 99.8 0.0 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KXG48896.1 - 5.4e-08 33.1 0.0 1.9e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KXG48896.1 - 0.00053 19.9 0.1 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 KXG48896.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KXG48896.1 - 0.026 14.6 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXG48896.1 - 0.026 14.9 0.0 0.072 13.5 0.0 1.8 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Arginase PF00491.21 KXG48898.1 - 2.2e-76 257.0 0.5 2.7e-76 256.8 0.5 1.0 1 0 0 1 1 1 1 Arginase family GatB_N PF02934.15 KXG48899.1 - 1.2e-97 326.6 0.0 1.9e-97 326.0 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KXG48899.1 - 1.2e-25 90.1 0.0 2.6e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 GatB domain Osw5 PF17062.5 KXG48900.1 - 0.35 11.0 2.6 0.91 9.7 2.6 1.6 1 0 0 1 1 1 0 Outer spore wall 5 COG4 PF08318.12 KXG48901.1 - 0.074 12.1 0.0 0.17 10.9 0.0 1.6 1 0 0 1 1 1 0 COG4 transport protein Bromodomain PF00439.25 KXG48901.1 - 0.17 12.0 0.1 0.53 10.4 0.1 1.8 1 0 0 1 1 1 0 Bromodomain NETI PF14044.6 KXG48902.1 - 0.16 11.7 0.0 5.1 6.9 0.0 2.4 2 0 0 2 2 2 0 NETI protein ECH_1 PF00378.20 KXG48903.1 - 2.2e-43 148.4 0.1 6.1e-43 146.9 0.1 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXG48903.1 - 6e-28 98.3 0.1 1e-27 97.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase LmjF365940-deam PF14421.6 KXG48903.1 - 0.11 12.1 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases NB-ARC PF00931.22 KXG48904.1 - 1.8e-11 43.8 0.0 2.9e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KXG48904.1 - 1.6e-05 25.3 0.0 3.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_6 PF12697.7 KXG48904.1 - 0.00027 21.6 0.0 0.00027 21.6 0.0 2.6 2 1 0 2 2 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KXG48904.1 - 0.00034 20.2 0.0 0.00094 18.7 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) NACHT PF05729.12 KXG48904.1 - 0.0024 17.8 0.1 0.022 14.7 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KXG48904.1 - 0.0027 18.0 0.0 0.0066 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KXG48904.1 - 0.0034 16.7 0.2 0.024 13.9 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin ATPase PF06745.13 KXG48904.1 - 0.01 15.2 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 KaiC PGAP1 PF07819.13 KXG48904.1 - 0.015 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein AAA_33 PF13671.6 KXG48904.1 - 0.067 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KXG48904.1 - 0.097 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 KXG48904.1 - 0.12 12.1 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KXG48904.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Podoplanin PF05808.11 KXG48905.1 - 1e-05 25.7 1.4 1.7e-05 25.0 0.3 1.8 2 0 0 2 2 2 1 Podoplanin DUF4690 PF15756.5 KXG48905.1 - 0.00011 22.8 3.6 0.00012 22.6 1.9 2.0 2 0 0 2 2 2 1 Small Novel Rich in Cartilage MGC-24 PF05283.11 KXG48905.1 - 0.00074 20.0 0.7 0.0016 18.9 0.7 1.5 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glycophorin_A PF01102.18 KXG48905.1 - 0.0039 17.4 0.0 0.0068 16.6 0.0 1.3 1 0 0 1 1 1 1 Glycophorin A BatD PF13584.6 KXG48905.1 - 0.075 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF2755 PF10954.8 KXG48905.1 - 0.097 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) MSA-2c PF12238.8 KXG48905.1 - 0.11 12.4 5.2 0.054 13.5 2.4 1.8 2 0 0 2 2 2 0 Merozoite surface antigen 2c SSP160 PF06933.11 KXG48905.1 - 0.99 7.5 9.1 1.4 7.1 9.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pkinase PF00069.25 KXG48906.1 - 4.1e-10 39.5 0.0 6.2e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48906.1 - 9.7e-07 28.3 0.0 2.1e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXG48906.1 - 0.0013 18.7 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG48906.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KXG48906.1 - 0.062 12.1 0.0 0.097 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXG48906.1 - 0.099 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3176 PF11374.8 KXG48907.1 - 6.8e-37 125.9 1.3 1.5e-36 124.8 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Aldo_ket_red PF00248.21 KXG48908.1 - 3.8e-73 246.3 0.0 4.3e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HHH_6 PF14579.6 KXG48908.1 - 0.16 12.2 0.0 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Transp_cyt_pur PF02133.15 KXG48909.1 - 4e-101 338.9 29.8 4.7e-101 338.7 29.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.6 KXG48910.1 - 2.3e-25 89.7 0.1 3.4e-25 89.1 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG48910.1 - 5.2e-19 68.6 0.0 1.1e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KXG48912.1 - 1.6e-39 135.9 59.7 8.8e-38 130.1 59.7 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG48912.1 - 3.4e-14 52.2 28.6 4.4e-14 51.8 28.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF883 PF05957.13 KXG48913.1 - 0.072 13.7 7.3 0.95 10.1 0.6 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KXG48913.1 - 0.58 10.7 17.7 2.9 8.5 2.4 3.0 1 1 1 2 2 2 0 YtxH-like protein Tn916-Xis PF09035.10 KXG48913.1 - 1 9.6 5.4 0.65 10.2 0.8 2.3 2 0 0 2 2 2 0 Excisionase from transposon Tn916 FHA PF00498.26 KXG48914.1 - 3.3e-13 49.8 0.0 5.9e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXG48914.1 - 0.076 13.3 0.0 1.9 8.9 0.0 2.5 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DnaJ PF00226.31 KXG48915.1 - 2.8e-10 40.2 0.8 5.3e-10 39.3 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain HATPase_c PF02518.26 KXG48916.1 - 2.3e-22 79.6 0.8 7e-22 78.1 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXG48916.1 - 1e-20 73.9 0.6 1.1e-19 70.7 0.2 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KXG48916.1 - 1.2e-16 60.5 1.0 4e-16 58.8 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KXG48916.1 - 9.1e-10 38.7 2.8 0.014 15.6 0.4 4.1 3 1 1 4 4 4 3 PAS fold PAS_4 PF08448.10 KXG48916.1 - 9.5e-06 25.8 0.1 0.00013 22.1 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 KXG48916.1 - 0.00075 19.7 0.0 0.39 11.0 0.0 3.6 3 1 0 3 3 3 1 PAS domain PAS PF00989.25 KXG48916.1 - 0.0037 17.2 0.0 4.4 7.3 0.0 3.2 2 0 0 2 2 2 2 PAS fold MotA_ExbB PF01618.16 KXG48916.1 - 0.052 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family HSBP1 PF06825.12 KXG48916.1 - 6.1 6.8 7.3 7.6 6.5 0.2 3.2 3 0 0 3 3 3 0 Heat shock factor binding protein 1 KxDL PF10241.9 KXG48917.1 - 8.6e-32 109.3 1.1 1.1e-31 108.9 1.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF4407 PF14362.6 KXG48917.1 - 0.024 14.0 1.8 0.028 13.8 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KXG48917.1 - 0.058 12.3 1.6 0.075 11.9 1.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Pectate_lyase_3 PF12708.7 KXG48918.1 - 3.1e-36 125.2 5.9 8.2e-19 68.3 1.9 2.9 2 0 0 2 2 2 2 Pectate lyase superfamily protein LysM PF01476.20 KXG48918.1 - 1.8e-11 43.9 0.3 0.0044 17.1 0.0 4.1 3 1 0 3 3 3 3 LysM domain End_N_terminal PF12218.8 KXG48918.1 - 0.0002 21.0 0.9 0.0014 18.3 0.3 2.2 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase Glyco_hydro_18 PF00704.28 KXG48919.1 - 7e-54 183.7 0.2 1e-51 176.5 0.2 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 AAA PF00004.29 KXG48921.1 - 1.8e-54 183.7 0.0 8e-40 136.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 KXG48921.1 - 4.3e-12 45.6 0.2 1.1e-10 41.1 0.1 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_lid_3 PF17862.1 KXG48921.1 - 8.6e-11 41.5 0.1 2e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KXG48921.1 - 7.5e-09 36.0 0.0 0.0001 22.6 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KXG48921.1 - 3e-08 34.2 0.3 0.0065 16.9 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 KXG48921.1 - 5.7e-07 29.8 0.0 4.2e-05 23.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KXG48921.1 - 1.7e-06 27.6 0.1 0.0044 16.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KXG48921.1 - 2.1e-06 27.6 0.2 0.073 12.8 0.1 2.9 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KXG48921.1 - 3e-06 26.7 0.1 0.024 13.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 KXG48921.1 - 4.5e-06 26.7 0.0 0.0012 18.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXG48921.1 - 4.8e-06 26.8 0.0 0.076 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KXG48921.1 - 5.6e-06 26.4 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.18 KXG48921.1 - 6.5e-06 26.2 0.0 1.6e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_18 PF13238.6 KXG48921.1 - 1.9e-05 25.2 0.0 0.087 13.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 KXG48921.1 - 5.5e-05 23.2 0.6 13 5.6 0.0 4.2 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KXG48921.1 - 8.2e-05 22.4 0.0 0.019 14.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXG48921.1 - 0.00036 20.9 0.0 0.063 13.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 KXG48921.1 - 0.00039 20.7 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KXG48921.1 - 0.00082 18.9 0.1 0.042 13.4 0.0 3.0 4 0 0 4 4 3 1 P-loop containing dynein motor region TsaE PF02367.17 KXG48921.1 - 0.0018 18.3 0.0 0.41 10.6 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KXG48921.1 - 0.0035 17.1 0.0 0.19 11.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 KXG48921.1 - 0.0052 16.2 0.1 0.074 12.4 0.1 2.3 2 0 0 2 2 2 1 KaiC Parvo_NS1 PF01057.17 KXG48921.1 - 0.0063 15.6 0.0 0.91 8.6 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 NACHT PF05729.12 KXG48921.1 - 0.0079 16.1 0.2 6 6.7 0.0 2.9 3 0 0 3 3 2 0 NACHT domain AAA_25 PF13481.6 KXG48921.1 - 0.008 15.8 0.5 3 7.4 0.0 3.1 2 2 1 3 3 3 1 AAA domain ABC_tran PF00005.27 KXG48921.1 - 0.0092 16.5 0.2 0.05 14.1 0.1 2.1 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 KXG48921.1 - 0.01 15.0 0.1 1.8 7.7 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_11 PF13086.6 KXG48921.1 - 0.02 14.7 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KXG48921.1 - 0.027 14.9 0.0 14 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KXG48921.1 - 0.031 13.7 0.0 6 6.2 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Sigma54_activat PF00158.26 KXG48921.1 - 0.034 13.9 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 KXG48921.1 - 0.038 13.9 0.0 0.49 10.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KXG48921.1 - 0.044 13.2 0.0 3.8 6.9 0.0 3.0 2 1 0 3 3 3 0 Bacterial TniB protein AAA_19 PF13245.6 KXG48921.1 - 0.056 13.8 0.0 0.72 10.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain PhoH PF02562.16 KXG48921.1 - 0.069 12.6 0.1 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 KXG48921.1 - 0.11 12.3 0.0 0.68 9.6 0.0 2.3 3 0 0 3 3 3 0 AAA domain Cir_N PF10197.9 KXG48922.1 - 6.8e-06 26.2 3.3 6.8e-06 26.2 3.3 3.1 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR 6PF2K PF01591.18 KXG48922.1 - 1.1 8.6 3.9 0.86 8.9 0.9 2.1 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Methyltransf_25 PF13649.6 KXG48923.1 - 1.9e-11 44.5 0.4 7.9e-11 42.5 0.0 2.3 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG48923.1 - 1.2e-09 38.6 0.0 4.2e-09 36.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXG48923.1 - 1.9e-09 37.4 0.2 4.6e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KXG48923.1 - 2.3e-08 34.0 0.0 6.3e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KXG48923.1 - 2e-06 27.8 0.3 4.3e-06 26.7 0.3 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXG48923.1 - 1.7e-05 24.4 0.2 4.1e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KXG48923.1 - 3.7e-05 23.6 0.0 9.3e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KXG48923.1 - 0.00051 19.5 0.1 0.00098 18.6 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 KXG48923.1 - 0.0016 17.5 0.1 0.0051 15.8 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 KXG48923.1 - 0.0024 18.6 0.2 0.01 16.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KXG48923.1 - 0.0053 16.5 0.0 0.0088 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 KXG48923.1 - 0.0067 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Ubie_methyltran PF01209.18 KXG48923.1 - 0.019 14.3 0.1 0.043 13.1 0.1 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KXG48923.1 - 0.027 15.5 0.0 0.1 13.7 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain PRMT5 PF05185.16 KXG48923.1 - 0.037 13.9 1.4 0.67 9.8 1.4 2.2 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.9 KXG48923.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Surfac_D-trimer PF09006.11 KXG48923.1 - 0.075 12.9 0.1 1.4 8.9 0.2 2.6 3 0 0 3 3 2 0 Lung surfactant protein D coiled-coil trimerisation Methyltransf_32 PF13679.6 KXG48923.1 - 0.089 12.8 0.4 0.77 9.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.18 KXG48923.1 - 0.095 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Mo25 PF08569.11 KXG48924.1 - 1.9e-128 428.5 0.2 2.1e-128 428.3 0.2 1.0 1 0 0 1 1 1 1 Mo25-like RepA_N PF06970.11 KXG48924.1 - 0.022 14.7 0.2 0.049 13.6 0.2 1.5 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus RabGAP-TBC PF00566.18 KXG48925.1 - 4.4e-33 114.7 0.0 8.8e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain 3HCDH_N PF02737.18 KXG48926.1 - 5.4e-30 104.6 0.0 8.8e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXG48926.1 - 1.8e-10 41.2 0.0 3.8e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 KXG48926.1 - 2.7e-07 30.7 0.0 3.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 KXG48926.1 - 1.9e-05 24.9 0.1 4.6e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXG48926.1 - 0.0038 17.8 0.3 0.0085 16.6 0.3 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 KXG48927.1 - 1.5e-40 139.2 29.8 2.1e-40 138.7 29.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_5_1 PF06946.11 KXG48927.1 - 0.28 11.6 0.1 0.28 11.6 0.1 2.4 3 0 0 3 3 3 0 Bacteriophage A118-like holin, Hol118 FeoB_C PF07664.12 KXG48927.1 - 0.34 10.6 0.0 0.34 10.6 0.0 4.2 5 1 1 6 6 6 0 Ferrous iron transport protein B C terminus MFS_1_like PF12832.7 KXG48927.1 - 4.8 5.9 16.9 0.04 12.8 2.7 2.5 2 1 0 3 3 3 0 MFS_1 like family Cg6151-P PF10233.9 KXG48928.1 - 1.1e-40 138.5 14.6 1.3e-40 138.2 14.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P PEMT PF04191.13 KXG48928.1 - 0.014 15.8 8.8 0.38 11.2 0.5 2.3 1 1 1 2 2 2 0 Phospholipid methyltransferase COPI_assoc PF08507.10 KXG48928.1 - 0.036 14.1 13.4 0.053 13.6 13.4 1.3 1 0 0 1 1 1 0 COPI associated protein DUF4149 PF13664.6 KXG48928.1 - 0.079 13.3 7.4 0.059 13.7 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) YfhO PF09586.10 KXG48928.1 - 0.84 7.8 5.4 1 7.5 5.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO IncE PF17627.2 KXG48928.1 - 1 9.4 6.8 0.22 11.5 2.2 2.0 2 0 0 2 2 2 0 Inclusion membrane protein E DUF3784 PF12650.7 KXG48928.1 - 1.3 9.3 13.9 0.82 9.9 5.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3784) DUF2892 PF11127.8 KXG48928.1 - 4.9 7.3 12.4 0.67 10.0 0.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2892) DUF202 PF02656.15 KXG48928.1 - 7.6 7.1 14.4 2.6 8.5 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) S_4TM PF18159.1 KXG48928.1 - 9.6 5.4 7.0 5.9 6.1 2.6 2.0 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain Aim21 PF11489.8 KXG48929.1 - 4.9e-247 822.5 74.3 4.9e-247 822.5 74.3 2.1 2 0 0 2 2 2 1 Altered inheritance of mitochondria protein 21 FANCL_C PF11793.8 KXG48930.1 - 3e-06 27.3 2.1 5.5e-06 26.5 2.1 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 KXG48930.1 - 1.3e-05 25.2 5.6 2.5e-05 24.3 5.6 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KXG48930.1 - 0.041 14.2 4.7 0.076 13.4 4.7 1.5 1 0 0 1 1 1 0 Ring finger domain MRP-L28 PF09812.9 KXG48931.1 - 1.1e-07 32.1 0.0 1.6e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DUF2489 PF10675.9 KXG48931.1 - 0.083 12.8 1.2 0.13 12.2 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Ras PF00071.22 KXG48932.1 - 5.4e-45 152.9 0.0 6.3e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXG48932.1 - 2.2e-19 69.8 0.0 4.8e-19 68.7 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG48932.1 - 4.6e-06 26.2 0.0 6.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXG48932.1 - 0.014 14.8 0.0 0.029 13.8 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KXG48932.1 - 0.06 13.1 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KXG48932.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NST1 PF13945.6 KXG48933.1 - 8.6e-68 228.2 0.0 8.6e-68 228.2 0.0 4.3 3 1 1 4 4 4 1 Salt tolerance down-regulator Red1 PF07964.11 KXG48933.1 - 8.1 4.5 33.9 24 3.0 33.9 1.8 1 0 0 1 1 1 0 Rec10 / Red1 Vps35 PF03635.17 KXG48934.1 - 0 1024.4 0.4 0 1024.2 0.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF4746 PF15928.5 KXG48934.1 - 0.018 14.5 5.6 0.03 13.8 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF913 PF06025.12 KXG48934.1 - 0.14 11.2 1.2 0.51 9.3 0.8 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CobT PF06213.12 KXG48934.1 - 0.2 11.0 10.7 0.37 10.1 10.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Vfa1 PF08432.10 KXG48934.1 - 0.21 11.9 7.4 0.36 11.1 7.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FancD2 PF14631.6 KXG48934.1 - 0.6 7.4 5.3 0.91 6.8 5.3 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Zn-ribbon_8 PF09723.10 KXG48935.1 - 0.12 12.5 4.0 0.57 10.3 0.9 3.0 3 0 0 3 3 3 0 Zinc ribbon domain AAA_12 PF13087.6 KXG48936.1 - 1.6e-40 138.8 0.0 2.7e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXG48936.1 - 5.6e-27 95.2 0.1 1.2e-26 94.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXG48936.1 - 6.3e-09 36.3 0.2 2.3e-07 31.2 0.1 3.1 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KXG48936.1 - 3.5e-06 26.5 0.4 0.024 13.9 0.1 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KXG48936.1 - 4.2e-05 23.4 0.3 0.0037 17.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 KXG48936.1 - 0.0014 18.2 0.0 0.0046 16.5 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KXG48936.1 - 0.0056 16.5 0.7 0.47 10.2 0.0 3.2 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KXG48936.1 - 0.032 14.2 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TPP_enzyme_N PF02776.18 KXG48937.1 - 5.3e-56 188.9 0.0 2.5e-54 183.5 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXG48937.1 - 2.9e-47 160.3 0.0 4.5e-46 156.4 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXG48937.1 - 9.5e-39 132.3 0.1 1.7e-38 131.5 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 KXG48937.1 - 0.13 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Uma2 PF05685.12 KXG48938.1 - 0.021 14.4 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative restriction endonuclease GalKase_gal_bdg PF10509.9 KXG48939.1 - 2.1e-19 68.8 0.0 4.9e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KXG48939.1 - 2e-15 56.8 1.8 5.3e-15 55.4 1.8 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXG48939.1 - 1e-12 48.3 0.0 2.5e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal RNase_H2-Ydr279 PF09468.10 KXG48940.1 - 6.1e-40 137.0 2.3 7.6e-40 136.7 0.1 2.3 2 1 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KXG48940.1 - 3e-20 72.3 0.1 8e-20 70.9 0.1 1.8 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain LIM_bind PF01803.16 KXG48940.1 - 0.9 9.0 6.0 0.46 10.0 0.4 2.2 2 0 0 2 2 2 0 LIM-domain binding protein zf-primase PF09329.11 KXG48941.1 - 1.3e-18 66.5 2.2 2.2e-18 65.8 2.2 1.4 1 0 0 1 1 1 1 Primase zinc finger DASH_Duo1 PF08651.10 KXG48943.1 - 5.2e-31 106.2 1.5 1.2e-30 105.1 1.5 1.6 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF5568 PF17724.1 KXG48943.1 - 0.042 13.7 3.9 0.067 13.0 3.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5568) DASH_Dad2 PF08654.10 KXG48943.1 - 0.13 12.7 4.8 0.3 11.5 4.8 1.6 1 1 0 1 1 1 0 DASH complex subunit Dad2 DUF4047 PF13256.6 KXG48943.1 - 0.14 12.3 1.1 0.28 11.4 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DUF745 PF05335.13 KXG48943.1 - 0.57 9.9 10.3 1.4 8.6 10.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) PP2C PF00481.21 KXG48944.1 - 2.6e-43 148.5 0.0 4.7e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KXG48944.1 - 1.4e-05 24.8 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KXG48944.1 - 0.054 13.4 0.0 13 5.7 0.0 2.6 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) TnpW PF14202.6 KXG48944.1 - 0.2 11.5 1.2 0.33 10.8 0.2 1.8 2 0 0 2 2 2 0 Transposon-encoded protein TnpW MFS_1 PF07690.16 KXG48945.1 - 8.5e-41 140.0 47.1 1.8e-39 135.7 44.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG48945.1 - 6e-17 61.3 17.5 3.4e-16 58.8 11.4 2.1 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) FCH PF00611.23 KXG48946.1 - 8e-14 51.7 0.5 6.9e-13 48.7 0.0 2.6 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KXG48946.1 - 3.1e-12 45.9 0.0 5.8e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXG48946.1 - 1.4e-11 43.9 0.0 4.7e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KXG48946.1 - 2.2e-11 43.4 0.0 4.1e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Rapsyn_N PF10579.9 KXG48946.1 - 0.13 12.3 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region F-box_5 PF18511.1 KXG48947.1 - 1.3 8.6 4.7 15 5.3 0.2 3.2 3 0 0 3 3 3 0 F-box WD40 PF00400.32 KXG48948.1 - 0.22 12.4 1.0 31 5.6 0.1 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat Abhydrolase_1 PF00561.20 KXG48949.1 - 7e-08 32.4 1.0 5.4e-07 29.5 1.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG48949.1 - 2.6e-07 31.5 2.7 3.2e-07 31.2 2.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG48949.1 - 0.0013 18.0 0.5 0.0016 17.8 0.5 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KXG48949.1 - 0.052 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) EHN PF06441.12 KXG48949.1 - 0.18 12.2 0.6 1.2 9.5 0.0 2.3 2 1 0 2 2 2 0 Epoxide hydrolase N terminus DUF1749 PF08538.10 KXG48950.1 - 6.7e-106 353.7 0.0 7.6e-106 353.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KXG48950.1 - 1.7e-05 25.6 0.0 2.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG48950.1 - 0.061 12.6 0.0 0.67 9.2 0.0 2.3 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Glycos_transf_2 PF00535.26 KXG48951.1 - 7e-36 123.6 0.0 8.4e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXG48951.1 - 1.7e-12 47.7 0.0 2.2e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KXG48951.1 - 2.7e-06 27.1 0.0 3.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXG48951.1 - 0.0007 19.1 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KXG48951.1 - 0.05 14.1 0.0 0.093 13.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KXG48951.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_transf_7N PF13733.6 KXG48951.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 TPR_19 PF14559.6 KXG48952.1 - 4.1e-05 24.0 0.2 0.69 10.5 0.0 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXG48952.1 - 0.016 15.3 0.1 48 4.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXG48952.1 - 0.021 15.5 0.3 0.12 13.0 0.0 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KXG48952.1 - 0.028 14.1 0.1 1.8 8.2 0.1 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_12 PF13424.6 KXG48952.1 - 0.049 13.9 0.2 1.9 8.9 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXG48952.1 - 0.059 13.5 0.1 39 4.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXG48952.1 - 0.081 13.6 0.7 10 7.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 KXG48953.1 - 5.4e-06 26.4 0.1 8.2e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KXG48953.1 - 0.00039 19.9 0.0 0.00057 19.4 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family HlyIII PF03006.20 KXG48954.1 - 4.1e-55 186.9 9.6 4.6e-55 186.8 9.6 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF998 PF06197.13 KXG48954.1 - 0.077 12.6 12.7 0.0095 15.5 5.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF3325 PF11804.8 KXG48954.1 - 0.14 12.3 0.2 0.14 12.3 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3325) adh_short_C2 PF13561.6 KXG48956.1 - 6.1e-47 160.1 4.4 2.6e-39 135.2 4.5 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG48956.1 - 4e-43 147.1 4.3 5.2e-43 146.8 4.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG48956.1 - 7.6e-15 55.3 0.7 1e-14 54.8 0.7 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXG48956.1 - 0.0026 17.7 0.8 0.0043 16.9 0.8 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KXG48956.1 - 0.0072 16.4 0.9 0.012 15.7 0.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Polysacc_synt_2 PF02719.15 KXG48956.1 - 0.056 12.6 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 KXG48956.1 - 0.11 12.0 0.4 0.18 11.4 0.4 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pkinase PF00069.25 KXG48957.1 - 4.4e-53 180.3 0.0 5.7e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48957.1 - 6.1e-33 114.2 0.0 7.5e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG48957.1 - 8.8e-06 25.2 0.0 0.00067 19.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXG48957.1 - 0.00019 21.4 0.0 0.0014 18.6 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXG48957.1 - 0.025 13.6 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KXG48957.1 - 0.039 13.3 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UL11 PF11094.8 KXG48957.1 - 0.08 12.8 0.1 0.22 11.4 0.1 1.8 1 0 0 1 1 1 0 Membrane-associated tegument protein Choline_kinase PF01633.20 KXG48957.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 KXG48957.1 - 0.12 12.0 0.0 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 KXG48958.1 - 1.2e-50 172.3 0.0 1.7e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48958.1 - 4.1e-22 78.7 0.0 8.9e-22 77.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KXG48958.1 - 0.071 12.1 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TMA7 PF09072.10 KXG48959.1 - 1.5e-22 80.2 22.0 1.6e-22 80.1 22.0 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 DHR10 PF18595.1 KXG48960.1 - 0.00092 19.3 4.0 0.0021 18.1 4.0 1.5 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain Cnn_1N PF07989.11 KXG48960.1 - 0.079 13.1 0.5 0.15 12.3 0.1 1.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Cyt-b5 PF00173.28 KXG48961.1 - 3.7e-14 52.6 0.0 5.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Surp PF01805.20 KXG48962.1 - 1.2e-12 47.6 0.0 2.8e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Surp module NTF2 PF02136.20 KXG48963.1 - 6.9e-35 120.2 0.3 7.7e-35 120.1 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 KXG48963.1 - 0.019 15.3 0.0 0.024 15.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) PQ-loop PF04193.14 KXG48964.1 - 1.4e-20 72.8 22.0 3.6e-12 45.9 2.2 3.3 3 1 1 4 4 4 2 PQ loop repeat DUF5400 PF17379.2 KXG48964.1 - 0.062 13.8 1.2 0.062 13.8 1.2 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5400) Ish1 PF10281.9 KXG48965.1 - 1.8e-82 271.3 18.4 3.6e-13 49.6 0.0 7.5 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.7 KXG48965.1 - 1.3e-09 37.6 0.3 0.14 11.9 0.1 5.7 6 0 0 6 6 6 2 HeH/LEM domain SAP PF02037.27 KXG48965.1 - 3.5e-09 36.2 0.0 1.6 8.6 0.0 6.4 6 1 0 6 6 6 2 SAP domain ANAPC2 PF08672.11 KXG48965.1 - 0.00011 22.7 0.3 31 5.2 0.0 5.6 7 0 0 7 7 5 0 Anaphase promoting complex (APC) subunit 2 Slx4 PF09494.10 KXG48965.1 - 0.0005 20.0 0.9 22 5.1 0.0 5.4 6 0 0 6 6 6 0 Slx4 endonuclease LEM PF03020.15 KXG48965.1 - 0.0032 17.0 0.0 23 4.7 0.0 4.4 4 0 0 4 4 4 0 LEM domain Thymopoietin PF08198.11 KXG48965.1 - 0.016 14.8 0.0 5.4 6.7 0.0 3.6 4 0 0 4 4 4 0 Thymopoietin protein CPSase_sm_chain PF00988.22 KXG48965.1 - 0.024 14.5 0.1 4 7.3 0.0 4.1 5 1 1 6 6 6 0 Carbamoyl-phosphate synthase small chain, CPSase domain SLATT_4 PF18186.1 KXG48965.1 - 0.036 13.7 1.2 0.1 12.2 1.2 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 Caudo_TAP PF02413.17 KXG48965.1 - 0.073 13.2 4.8 0.21 11.7 0.7 3.0 2 1 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK DUF4224 PF13986.6 KXG48965.1 - 0.15 12.0 0.0 19 5.2 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4224) 6PGD PF00393.19 KXG48965.1 - 0.34 10.2 8.7 0.42 9.9 1.7 3.8 3 2 2 5 5 5 0 6-phosphogluconate dehydrogenase, C-terminal domain HEPN_Swt1 PF18731.1 KXG48965.1 - 0.58 10.5 4.5 0.25 11.7 0.3 2.5 2 1 1 3 3 3 0 Swt1-like HEPN SAM_2 PF07647.17 KXG48965.1 - 8.9 6.5 7.0 44 4.3 0.3 4.4 6 0 0 6 6 5 0 SAM domain (Sterile alpha motif) APH PF01636.23 KXG48966.1 - 2.3e-12 47.4 0.0 4.9e-12 46.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KXG48966.1 - 0.22 10.3 0.0 2.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DUF3169 PF11368.8 KXG48967.1 - 0.012 15.1 0.4 0.02 14.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Not1 PF04054.15 KXG48968.1 - 3.8e-140 467.0 0.1 7.1e-140 466.1 0.1 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KXG48968.1 - 5.7e-96 320.3 0.6 1.5e-95 318.8 0.6 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KXG48968.1 - 2.2e-51 173.7 1.8 5.5e-51 172.4 1.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KXG48968.1 - 1.7e-41 141.5 0.0 4.7e-41 140.0 0.0 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KXG48968.1 - 1.1e-28 100.2 1.0 7.1e-28 97.6 0.0 2.8 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Zemlya PF17646.1 KXG48968.1 - 0.11 12.9 0.1 0.35 11.3 0.1 1.9 1 0 0 1 1 1 0 Closterovirus 1a polyprotein central region Seipin PF06775.14 KXG48969.1 - 2e-62 210.8 0.1 3e-62 210.2 0.1 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) TTL PF03133.15 KXG48969.1 - 9.6e-57 192.3 0.0 1.5e-56 191.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 KXG48969.1 - 4.8e-49 166.8 0.0 7.3e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 KXG48969.1 - 2.7e-05 23.5 0.0 0.00031 20.1 0.0 2.1 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KXG48969.1 - 0.042 13.1 0.0 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Glyco_trans_4_4 PF13579.6 KXG48969.1 - 0.09 13.2 0.9 0.21 12.0 0.1 2.1 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Dala_Dala_lig_C PF07478.13 KXG48969.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus PrpF PF04303.13 KXG48970.1 - 4.2e-110 368.2 0.5 4.9e-110 368.0 0.5 1.0 1 0 0 1 1 1 1 PrpF protein Pex14_N PF04695.13 KXG48972.1 - 9.1e-44 149.9 0.6 9.1e-44 149.9 0.6 3.2 2 1 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.12 KXG48972.1 - 0.011 15.7 3.7 1.1 9.3 1.2 2.5 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 KXG48972.1 - 0.046 11.2 3.9 0.061 10.8 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 KXG48972.1 - 0.062 12.8 1.6 0.095 12.1 1.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1043 PF06295.12 KXG48972.1 - 0.1 12.6 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF4211 PF13926.6 KXG48972.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) FlgN PF05130.12 KXG48972.1 - 0.21 12.1 5.7 0.34 11.4 5.7 1.3 1 0 0 1 1 1 0 FlgN protein Prominin PF05478.11 KXG48972.1 - 0.24 9.3 0.1 0.32 8.9 0.1 1.1 1 0 0 1 1 1 0 Prominin TRADD_N PF09034.10 KXG48972.1 - 0.29 11.2 0.6 0.47 10.5 0.6 1.3 1 0 0 1 1 1 0 TRADD, N-terminal domain LMBR1 PF04791.16 KXG48972.1 - 0.29 10.0 0.0 0.33 9.8 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ERM PF00769.19 KXG48972.1 - 0.4 10.4 8.0 0.18 11.6 4.3 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF1664 PF07889.12 KXG48972.1 - 0.87 9.6 4.8 0.33 11.0 0.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Ndc80_HEC PF03801.13 KXG48973.1 - 5.4e-60 201.5 0.0 1.2e-59 200.3 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family CENP-F_leu_zip PF10473.9 KXG48973.1 - 0.00039 20.5 10.5 0.00039 20.5 10.5 4.2 2 2 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 KXG48973.1 - 0.0042 16.7 20.9 0.0042 16.7 20.9 2.7 2 1 0 2 2 2 1 Intermediate filament protein DUF16 PF01519.16 KXG48973.1 - 0.014 15.9 7.7 0.014 15.9 7.7 3.8 3 1 1 4 4 4 0 Protein of unknown function DUF16 Strep_SA_rep PF06696.11 KXG48973.1 - 0.35 10.9 2.1 40 4.4 0.0 3.6 3 0 0 3 3 3 0 Streptococcal surface antigen repeat Prominin PF05478.11 KXG48973.1 - 1.9 6.4 19.9 0.094 10.7 6.4 2.1 2 0 0 2 2 2 0 Prominin Cep57_CLD PF14073.6 KXG48973.1 - 2.1 8.3 36.2 0.1 12.6 15.5 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 NPV_P10 PF05531.12 KXG48973.1 - 5.2 7.6 13.9 18 5.9 0.6 4.2 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 KXG48973.1 - 6.5 5.5 41.3 1.1 8.1 13.2 3.1 2 2 0 2 2 2 0 Spc7 kinetochore protein APH PF01636.23 KXG48974.1 - 5.5e-10 39.6 0.0 1.1e-09 38.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG48974.1 - 1.6e-05 24.6 0.0 8.1e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KXG48974.1 - 0.098 12.0 0.0 0.58 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain PT PF04886.12 KXG48974.1 - 0.13 11.8 69.8 0.1 12.2 28.3 4.1 2 2 1 3 3 3 0 PT repeat MFS_1 PF07690.16 KXG48975.1 - 1.1e-33 116.6 58.0 1.1e-32 113.3 58.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KXG48977.1 - 7.4e-17 61.2 0.0 1.3e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain A_deaminase PF00962.22 KXG48979.1 - 1.6e-37 129.6 0.0 1.9e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.16 KXG48980.1 - 4.6e-28 98.1 33.6 4.6e-28 98.1 33.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXG48980.1 - 1.5e-06 27.8 18.7 1.8e-05 24.2 5.3 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF2628 PF10947.8 KXG48980.1 - 1.1 9.6 6.6 0.2 12.0 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) Methyltransf_23 PF13489.6 KXG48981.1 - 2.8e-35 121.6 0.0 3.8e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG48981.1 - 5.4e-08 33.4 0.1 2.4e-07 31.4 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG48981.1 - 3.4e-07 30.9 0.0 7.3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG48981.1 - 7.6e-06 25.8 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG48981.1 - 2.3e-05 24.9 0.1 7.1e-05 23.4 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG48981.1 - 0.0032 16.8 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family zf-TFIIIC PF12660.7 KXG48981.1 - 0.018 15.0 0.0 0.035 14.0 0.0 1.5 1 1 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex TYA PF01021.19 KXG48981.1 - 0.031 14.6 3.5 0.07 13.5 3.5 1.5 1 0 0 1 1 1 0 TYA transposon protein DUF3611 PF12263.8 KXG48981.1 - 0.25 11.3 0.0 0.38 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) DAO PF01266.24 KXG48982.1 - 1.9e-45 156.0 1.1 2.2e-45 155.8 1.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG48982.1 - 3.2e-08 33.2 0.0 0.0069 15.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG48982.1 - 1.3e-06 28.5 0.5 0.077 13.0 0.0 2.6 2 1 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXG48982.1 - 5.9e-06 25.6 0.1 0.0026 16.9 0.0 2.3 2 1 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.22 KXG48982.1 - 2.3e-05 23.7 0.0 0.00018 20.7 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KXG48982.1 - 3.5e-05 22.9 0.0 0.014 14.3 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase GMC_oxred_N PF00732.19 KXG48982.1 - 0.00026 20.5 0.1 0.21 10.9 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 KXG48982.1 - 0.00027 21.1 0.8 0.00067 19.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXG48982.1 - 0.00088 19.8 0.0 0.0022 18.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG48982.1 - 0.00088 18.6 0.0 0.081 12.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG48982.1 - 0.0021 17.3 0.0 0.0065 15.7 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KXG48982.1 - 0.0022 17.2 0.4 0.035 13.2 0.4 2.1 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KXG48982.1 - 0.029 13.7 0.0 0.43 9.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase TrkA_N PF02254.18 KXG48982.1 - 0.031 14.5 0.0 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain K_oxygenase PF13434.6 KXG48982.1 - 0.093 11.9 0.0 3.5 6.7 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KXG48982.1 - 0.1 11.9 0.3 0.6 9.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 KXG48982.1 - 0.15 12.5 0.0 0.74 10.3 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding TBP PF00352.21 KXG48983.1 - 1.3e-67 223.7 0.1 9.5e-33 112.0 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KXG48983.1 - 6.7e-05 22.9 0.0 0.23 11.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KXG48983.1 - 0.14 12.0 0.1 0.69 9.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) ETF_QO PF05187.13 KXG48984.1 - 2.6e-47 159.3 0.5 4.1e-47 158.6 0.5 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KXG48984.1 - 2e-07 31.0 0.7 0.00039 20.1 0.5 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXG48984.1 - 4.9e-07 29.2 0.5 0.0018 17.4 0.9 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXG48984.1 - 1.6e-06 28.3 0.0 5.3e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG48984.1 - 1.9e-05 24.1 0.0 7.2e-05 22.2 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXG48984.1 - 0.00015 21.3 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXG48984.1 - 0.00044 19.1 0.5 0.00069 18.4 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KXG48984.1 - 0.00071 20.1 0.3 0.9 10.1 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG48984.1 - 0.00088 18.6 0.0 0.019 14.2 0.1 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KXG48984.1 - 0.00097 18.5 0.3 0.0019 17.5 0.3 1.5 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KXG48984.1 - 0.001 18.0 0.0 0.19 10.6 0.2 2.2 1 1 1 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 KXG48984.1 - 0.0012 18.8 0.2 0.0039 17.2 0.2 1.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXG48984.1 - 0.0072 15.6 0.7 0.012 14.9 0.7 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 KXG48984.1 - 0.022 15.3 0.9 0.06 14.0 0.9 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 KXG48984.1 - 0.084 11.9 0.3 0.12 11.4 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KXG48984.1 - 0.12 11.5 0.2 0.2 10.7 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_2 PF12797.7 KXG48984.1 - 0.12 12.6 0.6 0.3 11.3 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain RRM_1 PF00076.22 KXG48985.1 - 5.4e-24 83.8 0.0 5.5e-13 48.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXG48985.1 - 0.0057 16.5 0.0 0.051 13.4 0.0 2.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KXG48985.1 - 0.035 14.2 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif FolB PF02152.18 KXG48987.1 - 2.6e-25 89.1 0.0 1.8e-21 76.8 0.1 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase Pkinase PF00069.25 KXG48988.1 - 2.8e-65 220.3 0.0 3.6e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG48988.1 - 9.5e-28 97.2 0.0 1.4e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXG48988.1 - 0.0099 14.9 0.2 0.015 14.3 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KXG48988.1 - 0.027 13.2 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KXG48988.1 - 0.061 12.6 0.3 0.22 10.8 0.1 1.8 1 1 1 2 2 2 0 Kinase-like APH PF01636.23 KXG48988.1 - 0.18 11.7 0.4 1.1 9.2 0.2 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cyclin_N PF00134.23 KXG48989.1 - 4.8e-15 55.4 1.3 1.1e-14 54.2 0.6 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXG48989.1 - 0.00013 22.0 0.1 0.0021 18.2 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain Pex24p PF06398.11 KXG48989.1 - 0.025 13.6 0.1 0.21 10.6 0.0 2.0 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Cyclin_C_2 PF16899.5 KXG48989.1 - 0.053 13.9 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 Cyclin C-terminal domain TFIIB PF00382.19 KXG48989.1 - 1.2 9.2 4.2 2.2 8.4 0.6 2.5 2 0 0 2 2 2 0 Transcription factor TFIIB repeat HNH_2 PF13391.6 KXG48990.1 - 1.2e-08 35.0 0.1 2.2e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease EAF PF09816.9 KXG48991.1 - 1e-19 70.7 0.2 2e-19 69.9 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor AMPK1_CBM PF16561.5 KXG48992.1 - 6.4e-18 64.8 0.8 1.2e-17 63.9 0.8 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 KXG48992.1 - 0.082 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) cNMP_binding PF00027.29 KXG48993.1 - 2.3e-40 136.6 0.0 6.4e-21 74.2 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain 2OG-FeII_Oxy_3 PF13640.6 KXG48994.1 - 6.2e-10 39.8 0.0 9.7e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Forkhead PF00250.18 KXG48995.1 - 4.4e-17 62.1 0.0 9.2e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KXG48995.1 - 9.3e-07 29.1 0.0 1.9e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain Aminotran_1_2 PF00155.21 KXG48996.1 - 1.7e-65 221.6 0.0 2.1e-65 221.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Tmemb_18A PF09771.9 KXG48996.1 - 0.088 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 188 Beta_elim_lyase PF01212.21 KXG48996.1 - 0.12 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase AMP-binding PF00501.28 KXG48997.1 - 7.5e-39 133.5 0.0 1.2e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KXG48997.1 - 1.3e-09 37.9 2.6 1.7e-09 37.5 1.0 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KXG48997.1 - 0.00022 22.2 0.0 0.00078 20.4 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TrkH PF02386.16 KXG48998.1 - 6.6e-26 90.8 0.3 6.6e-26 90.8 0.3 1.9 2 0 0 2 2 2 1 Cation transport protein UPF0542 PF15086.6 KXG48998.1 - 0.041 13.8 0.2 0.13 12.2 0.2 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Peptidase_M16_C PF05193.21 KXG49001.1 - 1e-50 172.3 0.0 5.1e-50 170.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXG49001.1 - 8.5e-41 139.4 0.0 3.3e-39 134.2 0.0 2.1 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Tom22 PF04281.13 KXG49002.1 - 7.8e-51 171.5 1.1 8.9e-51 171.3 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4211 PF13926.6 KXG49003.1 - 1.8e-41 141.6 1.5 9.5e-41 139.2 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4211) Sugar_tr PF00083.24 KXG49004.1 - 5.4e-100 335.4 23.2 6.3e-100 335.2 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG49004.1 - 1.6e-35 122.7 43.8 4.6e-29 101.5 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1980 PF09323.10 KXG49004.1 - 0.092 12.7 0.0 0.56 10.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) ketoacyl-synt PF00109.26 KXG49005.1 - 4.1e-69 233.0 0.7 1.1e-68 231.6 0.7 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXG49005.1 - 4.9e-31 107.2 0.0 1.4e-30 105.7 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KXG49005.1 - 2.5e-26 92.4 0.0 6e-26 91.2 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Acyl_transf_1 PF00698.21 KXG49005.1 - 1.5e-23 83.9 1.9 3.2e-23 82.8 1.9 1.5 1 0 0 1 1 1 1 Acyl transferase domain HTH_51 PF18558.1 KXG49005.1 - 1.9e-21 75.8 0.0 4.4e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain PP-binding PF00550.25 KXG49005.1 - 6.9e-15 55.2 3.1 1.5e-12 47.6 0.1 3.3 3 0 0 3 3 3 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KXG49005.1 - 1.9e-12 47.8 0.0 4.7e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG49005.1 - 5.5e-11 43.0 0.0 1.1e-09 38.8 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG49005.1 - 7.1e-10 39.0 0.0 1.9e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 KXG49005.1 - 1.1e-09 38.4 13.6 1.5e-08 34.6 0.1 5.0 5 0 0 5 5 5 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_11 PF08241.12 KXG49005.1 - 1.5e-07 31.9 0.0 6.8e-07 29.9 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KXG49005.1 - 2.9e-07 30.1 0.2 1e-06 28.3 0.2 1.9 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 KXG49005.1 - 4.9e-07 29.7 0.0 2.2e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.21 KXG49005.1 - 6.6e-07 29.0 0.0 1.7e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 KXG49005.1 - 0.00019 21.8 0.0 0.00072 20.0 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension DXP_reductoisom PF02670.16 KXG49005.1 - 0.0039 17.9 0.0 0.023 15.4 0.0 2.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 KXG49005.1 - 0.018 15.2 0.1 0.078 13.1 0.0 2.1 2 0 0 2 2 1 0 Dihydrodipicolinate reductase, N-terminus ACP_syn_III PF08545.10 KXG49005.1 - 0.02 14.7 2.4 0.036 13.9 0.4 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III KR PF08659.10 KXG49005.1 - 0.021 14.7 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 KXG49005.1 - 0.084 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ribosomal_60s PF00428.19 KXG49005.1 - 8.2 7.1 8.0 8.9 7.0 4.9 2.8 2 0 0 2 2 1 0 60s Acidic ribosomal protein FAD_binding_3 PF01494.19 KXG49006.1 - 8.3e-24 84.5 0.0 1.3e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXG49006.1 - 3.8e-07 30.0 0.7 9.5e-07 28.7 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG49006.1 - 0.0005 20.2 0.0 0.0015 18.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXG49006.1 - 0.00075 20.0 2.8 0.0031 18.0 1.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXG49006.1 - 0.0046 16.9 0.1 0.0079 16.1 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.10 KXG49006.1 - 0.01 14.9 0.0 0.18 10.8 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.14 KXG49006.1 - 0.022 14.0 0.3 0.054 12.7 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG49006.1 - 0.024 13.9 0.1 0.23 10.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3721 PF12518.8 KXG49006.1 - 0.084 12.7 2.5 7.5 6.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function HI0933_like PF03486.14 KXG49006.1 - 0.086 11.5 0.6 0.12 11.0 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_4 PF01565.23 KXG49007.1 - 1.2e-23 83.4 2.0 2e-23 82.7 2.0 1.3 1 0 0 1 1 1 1 FAD binding domain SnoaL_4 PF13577.6 KXG49008.1 - 4.5e-16 59.1 0.5 5.6e-16 58.8 0.5 1.0 1 0 0 1 1 1 1 SnoaL-like domain Fungal_trans PF04082.18 KXG49009.1 - 3.7e-13 49.1 0.0 1.3e-12 47.3 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.12 KXG49010.1 - 2.6e-10 40.1 0.1 1e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG49010.1 - 8.8e-08 32.2 0.3 1.7e-07 31.3 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.16 KXG49011.1 - 1.8e-37 129.1 49.9 1.8e-37 129.1 49.9 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG49011.1 - 3.4e-11 42.3 18.3 5.3e-11 41.7 18.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5559 PF17714.1 KXG49012.1 - 0.05 13.5 0.3 0.11 12.3 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5559) DUF5434 PF17502.2 KXG49012.1 - 0.15 12.0 2.4 0.098 12.6 0.4 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5434) Cep57_CLD PF14073.6 KXG49012.1 - 0.29 11.1 3.2 0.29 11.2 0.7 2.0 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Spt20 PF12090.8 KXG49012.1 - 5.9 6.4 10.2 2.3 7.8 5.4 2.1 2 0 0 2 2 2 0 Spt20 family Transferase PF02458.15 KXG49013.1 - 1e-09 37.6 0.0 1.4e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Transferase family ketoacyl-synt PF00109.26 KXG49014.1 - 7.2e-70 235.4 0.3 1.6e-69 234.3 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXG49014.1 - 6.9e-59 198.8 0.0 3.4e-58 196.5 0.0 2.3 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KXG49014.1 - 2.1e-55 188.1 0.3 4.4e-55 187.0 0.3 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXG49014.1 - 1.8e-47 162.4 2.2 3.9e-47 161.3 2.2 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXG49014.1 - 1.7e-34 118.3 0.1 9.8e-34 115.9 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXG49014.1 - 2.6e-16 60.1 0.0 9.3e-16 58.3 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KXG49014.1 - 4.2e-16 60.2 0.8 3.5e-15 57.2 0.1 3.1 4 0 0 4 4 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXG49014.1 - 1.8e-13 50.6 1.6 8.9e-13 48.4 0.0 3.0 3 1 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KXG49014.1 - 4.1e-09 37.1 0.0 1.3e-07 32.3 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG49014.1 - 2e-07 31.0 0.0 4.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXG49014.1 - 6.8e-07 28.9 0.0 2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 KXG49014.1 - 0.00072 19.9 0.8 0.0028 18.0 0.8 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAT PF16073.5 KXG49014.1 - 0.0017 18.1 0.3 0.0051 16.6 0.3 1.8 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_31 PF13847.6 KXG49014.1 - 0.0022 17.8 0.0 0.0054 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG49014.1 - 0.0027 18.3 0.0 0.011 16.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KXG49014.1 - 0.0042 16.5 0.6 0.026 13.9 0.1 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KXG49014.1 - 0.0077 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.12 KXG49014.1 - 0.015 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Sacchrp_dh_NADP PF03435.18 KXG49014.1 - 0.015 15.5 0.0 0.18 12.0 0.0 2.8 3 0 0 3 3 2 0 Saccharopine dehydrogenase NADP binding domain TauD PF02668.16 KXG49015.1 - 9.8e-33 114.1 0.1 1.5e-32 113.5 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXG49015.1 - 0.19 10.8 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 CsiD MFS_1 PF07690.16 KXG49016.1 - 2.4e-23 82.7 24.5 2.4e-23 82.7 24.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2142 PF09913.9 KXG49016.1 - 0.024 13.5 7.1 0.058 12.3 7.1 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2142) DUF2530 PF10745.9 KXG49016.1 - 0.046 14.0 0.5 0.046 14.0 0.5 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2530) DUF4534 PF15049.6 KXG49016.1 - 0.091 12.5 0.6 0.23 11.2 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4534) FMO-like PF00743.19 KXG49017.1 - 1.3e-17 63.5 0.0 3.1e-17 62.2 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXG49017.1 - 8.7e-12 44.9 0.1 4e-10 39.4 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG49017.1 - 1.6e-06 28.2 0.7 2.2e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXG49017.1 - 1.2e-05 24.7 0.6 0.0021 17.4 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG49017.1 - 4.2e-05 22.9 0.5 0.0061 15.7 0.2 3.2 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXG49017.1 - 4.2e-05 23.6 0.0 0.00015 21.8 0.0 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXG49017.1 - 0.0032 18.0 0.4 0.74 10.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG49017.1 - 0.039 13.6 0.0 2.9 7.4 0.0 2.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXG49017.1 - 0.05 12.9 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KXG49017.1 - 0.083 12.1 0.3 1.1 8.4 0.0 2.4 3 0 0 3 3 3 0 Thi4 family HI0933_like PF03486.14 KXG49017.1 - 0.23 10.1 0.7 0.41 9.3 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein zf-C3HC4_3 PF13920.6 KXG49018.1 - 0.00012 21.9 3.6 0.00031 20.6 3.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXG49018.1 - 0.0066 16.4 7.8 0.0066 16.4 7.8 2.3 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXG49018.1 - 0.02 14.7 7.8 0.02 14.7 7.8 2.6 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXG49018.1 - 0.15 12.0 4.9 0.44 10.4 4.9 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXG49018.1 - 0.73 9.9 13.9 0.8 9.8 4.6 3.6 3 1 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXG49018.1 - 0.92 9.7 7.2 0.88 9.8 3.3 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KXG49018.1 - 2.5 8.5 14.1 2.9 8.3 6.6 3.0 3 1 0 3 3 3 0 Ring finger domain DUF3405 PF11885.8 KXG49019.1 - 1.2e-233 776.4 0.3 1.6e-233 776.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Fic PF02661.18 KXG49020.1 - 2.1e-18 67.0 0.0 7.5e-18 65.2 0.0 2.0 1 0 0 1 1 1 1 Fic/DOC family HTH_51 PF18558.1 KXG49020.1 - 0.026 14.4 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Arf PF00025.21 KXG49021.1 - 1.4e-77 259.0 0.1 2.2e-77 258.4 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXG49021.1 - 7.4e-14 51.6 0.0 1.2e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KXG49021.1 - 2.4e-13 50.3 0.0 4.9e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXG49021.1 - 5.7e-12 45.5 0.0 9.3e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KXG49021.1 - 1.1e-11 44.5 0.8 1.6e-08 34.1 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KXG49021.1 - 2e-09 37.2 0.0 3.4e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXG49021.1 - 3.5e-05 23.9 0.0 7.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SieB PF14163.6 KXG49021.1 - 0.088 12.3 1.8 0.2 11.1 1.8 1.5 1 0 0 1 1 1 0 Super-infection exclusion protein B 6PF2K PF01591.18 KXG49021.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CorA PF01544.18 KXG49021.1 - 0.55 9.5 4.8 0.9 8.8 0.3 2.7 4 0 0 4 4 4 0 CorA-like Mg2+ transporter protein Ribosomal_L1 PF00687.21 KXG49022.1 - 2.1e-46 158.2 0.6 2.4e-46 158.0 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DEK_C PF08766.11 KXG49022.1 - 0.063 13.2 0.5 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 DEK C terminal domain WH2 PF02205.20 KXG49024.1 - 8.9e-11 41.3 3.3 2.3e-10 40.0 1.1 2.4 2 0 0 2 2 2 1 WH2 motif LSM PF01423.22 KXG49025.1 - 6.7e-15 54.5 0.1 8.8e-15 54.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain SURF4 PF02077.15 KXG49028.1 - 4.4e-94 315.0 8.3 4.9e-94 314.9 8.3 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 KXG49028.1 - 0.59 10.8 20.3 0.48 11.1 0.7 3.0 3 2 0 3 3 3 0 DoxX Halogen_Hydrol PF10112.9 KXG49028.1 - 7.6 6.5 7.0 13 5.8 2.8 2.5 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Atg14 PF10186.9 KXG49029.1 - 1.3 8.0 9.6 0.092 11.8 5.0 1.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4574 PF15141.6 KXG49029.1 - 3.8 7.5 7.4 34 4.4 6.5 2.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 IU_nuc_hydro PF01156.19 KXG49030.1 - 5e-56 190.5 0.0 8.8e-56 189.7 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF2249 PF10006.9 KXG49030.1 - 0.05 13.5 0.0 0.28 11.1 0.0 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Transketolase_C PF02780.20 KXG49030.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Transketolase, C-terminal domain HLH PF00010.26 KXG49032.1 - 1.2e-13 50.8 0.1 2.2e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FERM_M PF00373.18 KXG49032.1 - 0.046 14.1 0.0 0.084 13.3 0.0 1.5 1 0 0 1 1 1 0 FERM central domain TEBP_beta PF07404.11 KXG49032.1 - 6.3 6.0 8.1 11 5.2 8.1 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Fungal_trans PF04082.18 KXG49033.1 - 1.8e-17 63.3 0.1 3e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG49033.1 - 3.7e-09 36.6 8.9 6.8e-09 35.7 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXG49035.1 - 7.5e-37 127.1 34.0 7.5e-37 127.1 34.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG49035.1 - 5.9e-11 41.9 4.6 5.9e-11 41.9 4.6 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter APH PF01636.23 KXG49037.1 - 7.2e-15 55.6 0.0 4.8e-14 52.9 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG49037.1 - 0.0013 18.4 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KXG49037.1 - 0.16 11.3 0.0 0.37 10.1 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain FMO-like PF00743.19 KXG49038.1 - 4.3e-23 81.5 0.0 2.2e-22 79.2 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXG49038.1 - 1.2e-20 74.0 0.0 8.1e-20 71.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG49038.1 - 6.9e-13 48.5 0.0 1.5e-10 40.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG49038.1 - 4.4e-10 39.2 0.1 7.7e-08 31.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KXG49038.1 - 1.7e-07 30.8 0.8 0.00073 18.9 0.3 3.1 2 1 1 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 KXG49038.1 - 3.9e-06 27.0 0.0 0.00029 21.0 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KXG49038.1 - 5e-06 26.0 0.0 0.0098 15.3 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KXG49038.1 - 8e-06 26.3 0.2 0.11 13.0 0.1 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 KXG49038.1 - 0.00029 20.5 0.1 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_9 PF13454.6 KXG49038.1 - 0.00052 20.0 0.1 0.98 9.4 0.0 3.3 2 1 1 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXG49038.1 - 0.00053 19.1 0.1 0.043 12.9 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein 3HCDH_N PF02737.18 KXG49038.1 - 0.0015 18.5 0.1 0.058 13.3 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXG49038.1 - 0.0017 18.6 0.1 0.45 10.8 0.0 2.6 3 0 0 3 3 2 1 TrkA-N domain FAD_binding_2 PF00890.24 KXG49038.1 - 0.0025 17.0 0.6 0.017 14.2 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_2 PF03446.15 KXG49038.1 - 0.0075 16.5 0.6 1.7 8.8 0.2 2.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 KXG49038.1 - 0.01 16.2 0.0 0.16 12.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 KXG49038.1 - 0.012 14.3 0.9 0.53 8.9 0.0 2.6 4 0 0 4 4 4 0 HI0933-like protein Shikimate_DH PF01488.20 KXG49038.1 - 0.028 14.5 0.0 0.51 10.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KXG49038.1 - 0.037 13.3 0.1 6 6.1 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KXG49038.1 - 0.042 13.5 0.0 15 5.2 0.0 2.8 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KXG49038.1 - 0.045 12.8 0.2 8 5.4 0.1 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A ELFV_dehydrog PF00208.21 KXG49038.1 - 0.16 11.7 0.6 0.28 10.9 0.6 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase UDPG_MGDP_dh_N PF03721.14 KXG49038.1 - 0.21 11.1 0.3 1.8 8.1 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Transferase PF02458.15 KXG49039.1 - 0.0063 15.2 0.0 0.11 11.1 0.0 2.3 1 1 0 1 1 1 1 Transferase family CLASP_N PF12348.8 KXG49041.1 - 1.6e-147 489.1 0.0 2.8e-86 288.8 0.0 2.3 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 KXG49041.1 - 2.7e-10 39.6 0.2 0.04 14.2 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 KXG49041.1 - 6.9e-08 32.7 0.0 0.048 13.7 0.0 4.2 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXG49041.1 - 7.4e-05 23.1 2.5 15 6.1 0.1 5.6 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KXG49041.1 - 0.0011 19.4 0.2 2 9.0 0.0 3.5 3 0 0 3 3 3 2 HEAT-like repeat Fanconi_A_N PF15865.5 KXG49041.1 - 0.022 14.2 0.4 3.7 6.8 0.1 2.6 2 0 0 2 2 2 0 Fanconi anaemia group A protein N terminus DUF3361 PF11841.8 KXG49041.1 - 0.062 13.2 0.5 0.88 9.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) Condensin2nSMC PF12422.8 KXG49041.1 - 0.11 12.6 0.0 17 5.6 0.0 3.1 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit BSP PF04450.12 KXG49042.1 - 2.5e-76 256.1 0.0 3e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Ribonuclease_3 PF00636.26 KXG49043.1 - 1.3e-06 29.0 0.0 1e-05 26.1 0.0 2.3 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXG49043.1 - 1.6e-06 28.3 0.0 0.00049 20.2 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.26 KXG49043.1 - 3e-05 24.6 0.2 9.7e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif PfkB PF00294.24 KXG49045.1 - 3.5e-11 43.0 0.0 9.5e-11 41.5 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase CAP_N PF01213.19 KXG49046.1 - 3.2e-112 375.1 10.4 3.2e-112 375.1 10.4 2.4 2 1 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KXG49046.1 - 1.7e-58 196.6 0.9 2.4e-58 196.2 0.9 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KXG49046.1 - 0.3 10.8 4.2 5.7 6.7 3.3 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor C Totivirus_coat PF05518.11 KXG49046.1 - 5.8 4.8 8.8 11 3.9 8.8 1.4 1 0 0 1 1 1 0 Totivirus coat protein DUF4210 PF13915.6 KXG49047.1 - 1.5e-31 108.8 0.3 7.3e-31 106.6 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 KXG49047.1 - 1.6e-21 76.2 1.2 1.6e-21 76.2 1.2 1.9 2 0 0 2 2 2 1 Chromosome segregation during meiosis TOH_N PF12549.8 KXG49047.1 - 0.079 12.8 2.6 0.37 10.7 2.6 2.2 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal rRNA_processing PF08524.11 KXG49048.1 - 0.022 14.8 22.1 0.071 13.1 22.1 1.7 1 1 0 1 1 1 0 rRNA processing Presenilin PF01080.17 KXG49048.1 - 3 6.5 5.1 3.7 6.2 5.1 1.1 1 0 0 1 1 1 0 Presenilin Sec5 PF15469.6 KXG49049.1 - 3e-36 125.0 0.0 9.4e-36 123.4 0.0 1.9 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 KXG49049.1 - 2.9e-05 24.0 0.2 0.0001 22.3 0.2 2.0 1 0 0 1 1 1 1 Vps51/Vps67 Sec15 PF04091.12 KXG49049.1 - 0.0064 15.9 0.5 0.015 14.7 0.1 1.8 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like COG2 PF06148.11 KXG49049.1 - 0.078 13.1 0.1 0.29 11.2 0.1 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 GTP-bdg_M PF16360.5 KXG49049.1 - 0.12 13.0 3.0 0.26 11.9 0.3 2.6 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region DUF445 PF04286.12 KXG49049.1 - 0.32 10.8 1.7 12 5.5 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF445) CtIP_N PF10482.9 KXG49049.1 - 0.39 10.8 1.6 1.8 8.6 0.1 2.7 3 0 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Iso_dh PF00180.20 KXG49050.1 - 2.7e-101 339.2 0.0 3.4e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.7 KXG49050.1 - 0.01 15.9 0.1 0.31 11.1 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Eaf7 PF07904.13 KXG49051.1 - 3.8e-29 101.2 0.0 9.6e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Nop14 PF04147.12 KXG49051.1 - 0.82 7.8 7.0 1.3 7.1 7.0 1.4 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KXG49051.1 - 0.9 8.8 6.7 1.8 7.8 6.7 1.5 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 KXG49051.1 - 5.5 5.1 12.2 8.1 4.6 12.2 1.2 1 0 0 1 1 1 0 CDC45-like protein GCP_C_terminal PF04130.13 KXG49052.1 - 1.2e-66 225.3 0.0 1.7e-66 224.8 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KXG49052.1 - 9.6e-55 186.3 0.0 1.5e-54 185.7 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Mo-co_dimer PF03404.16 KXG49053.1 - 5.6e-59 198.1 0.3 1.1e-58 197.1 0.3 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 KXG49053.1 - 3.9e-52 176.3 0.0 6.8e-52 175.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 KXG49053.1 - 1e-34 118.8 0.0 1.7e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXG49053.1 - 3.3e-30 104.9 0.0 6.5e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KXG49053.1 - 2.1e-16 59.8 0.0 4e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KXG49053.1 - 0.0047 17.1 0.0 0.77 9.9 0.0 2.4 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Pyr_redox_2 PF07992.14 KXG49054.1 - 3.4e-43 147.9 0.4 6.3e-43 147.1 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 KXG49054.1 - 5.3e-22 78.0 0.0 1.2e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Rieske_2 PF13806.6 KXG49054.1 - 1.9e-16 59.9 0.0 4.2e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.27 KXG49054.1 - 1.1e-14 54.8 0.8 1.1e-14 54.8 0.8 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KXG49054.1 - 2.9e-14 52.8 0.2 1.5e-13 50.5 0.0 2.3 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Fer2_BFD PF04324.15 KXG49054.1 - 3e-14 53.1 9.6 1.7e-12 47.5 5.9 2.9 3 0 0 3 3 3 2 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 KXG49054.1 - 7.2e-11 41.8 0.0 1.7e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 KXG49054.1 - 6.2e-06 26.0 0.4 0.021 14.7 0.0 3.0 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 KXG49054.1 - 0.00047 20.2 0.8 0.65 10.0 0.0 3.3 3 1 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXG49054.1 - 0.0087 15.2 0.0 0.0087 15.2 0.0 1.8 2 1 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 KXG49054.1 - 0.12 12.9 0.1 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding MFS_1 PF07690.16 KXG49055.1 - 5.5e-24 84.7 49.9 1.9e-22 79.7 25.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily rhaM PF05336.13 KXG49056.1 - 7.9e-38 128.8 0.1 8.9e-38 128.7 0.1 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase Abhydrolase_1 PF00561.20 KXG49057.1 - 1.4e-20 74.1 0.7 2.3e-20 73.3 0.4 1.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG49057.1 - 3.8e-16 59.1 0.0 1.1e-15 57.6 0.1 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXG49057.1 - 8.5e-16 59.2 3.1 1.2e-15 58.8 3.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KXG49057.1 - 0.00018 20.3 0.0 0.00026 19.8 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 KXG49057.1 - 0.00027 20.7 0.0 0.0006 19.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KXG49057.1 - 0.0005 19.9 0.0 0.00071 19.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.11 KXG49057.1 - 0.0013 18.1 0.2 0.002 17.5 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KXG49057.1 - 0.004 16.8 0.0 0.011 15.4 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Eno-Rase_NADH_b PF12242.8 KXG49057.1 - 0.0066 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Say1_Mug180 PF10340.9 KXG49057.1 - 0.012 14.5 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 0 Steryl acetyl hydrolase UPF0227 PF05728.12 KXG49057.1 - 0.068 13.1 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF676 PF05057.14 KXG49057.1 - 0.088 12.3 0.4 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 KXG49057.1 - 0.12 12.3 0.1 2.4 8.0 0.0 2.2 1 1 0 2 2 2 0 Serine hydrolase Lipase_2 PF01674.18 KXG49057.1 - 0.14 11.6 0.1 0.33 10.5 0.1 1.6 1 1 0 1 1 1 0 Lipase (class 2) DUF1057 PF06342.12 KXG49057.1 - 0.19 10.8 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) TPR_19 PF14559.6 KXG49058.1 - 0.055 14.0 14.3 34 5.0 0.0 7.4 7 1 0 7 7 7 0 Tetratricopeptide repeat Na_Ca_ex_C PF16494.5 KXG49058.1 - 6.1 7.3 13.5 22 5.5 0.0 4.2 4 0 0 4 4 4 0 C-terminal extension of sodium/calcium exchanger domain Ribosomal_L5e PF17144.4 KXG49060.1 - 9.2e-83 276.1 0.5 2.4e-82 274.8 0.5 1.8 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KXG49060.1 - 2.7e-32 111.6 11.4 2.7e-32 111.6 11.4 2.1 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region HAD_2 PF13419.6 KXG49060.1 - 9.7e-08 32.3 1.1 3.1e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXG49060.1 - 1.7e-05 24.8 0.0 3.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KXG49060.1 - 0.0013 19.0 0.1 0.013 15.8 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase MtrA PF04208.14 KXG49060.1 - 0.037 13.7 0.3 0.068 12.8 0.3 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A PrmC_N PF17827.1 KXG49060.1 - 0.062 13.9 0.0 16 6.2 0.0 2.8 2 0 0 2 2 2 0 PrmC N-terminal domain FTA4 PF13093.6 KXG49061.1 - 2.8e-55 187.3 8.2 2.8e-55 187.3 8.2 2.4 2 1 1 3 3 3 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 RRF_GI PF12614.8 KXG49061.1 - 0.0028 17.8 1.4 0.0091 16.2 1.4 1.8 1 0 0 1 1 1 1 Ribosome recycling factor PE PF00934.20 KXG49061.1 - 0.22 11.8 2.1 0.52 10.7 0.1 2.4 2 0 0 2 2 2 0 PE family DUF4404 PF14357.6 KXG49061.1 - 2.5 8.8 9.8 0.65 10.7 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) HalX PF08663.10 KXG49061.1 - 2.7 8.4 8.9 14 6.1 5.5 3.1 2 0 0 2 2 2 0 HalX domain Exonuc_VII_L PF02601.15 KXG49061.1 - 6.6 6.2 12.4 1.8 8.0 2.9 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Prefoldin_2 PF01920.20 KXG49061.1 - 6.7 6.7 8.6 0.99 9.4 2.9 2.5 2 1 0 2 2 2 0 Prefoldin subunit ABC_membrane_2 PF06472.15 KXG49063.1 - 2.9e-104 348.2 0.6 2.9e-104 348.2 0.6 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KXG49063.1 - 4.8e-19 69.2 0.0 9.2e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXG49063.1 - 7.8e-05 22.6 0.0 0.00025 20.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXG49063.1 - 0.004 17.7 0.0 0.0099 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KXG49063.1 - 0.022 14.5 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 KXG49063.1 - 0.025 14.0 0.1 0.15 11.5 0.1 2.2 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Reticulon PF02453.17 KXG49063.1 - 0.03 14.3 0.1 0.062 13.3 0.1 1.5 1 0 0 1 1 1 0 Reticulon RuvB_N PF05496.12 KXG49063.1 - 0.058 13.1 0.1 1.5 8.5 0.0 2.8 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain AAA_27 PF13514.6 KXG49063.1 - 0.11 12.1 0.0 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KXG49063.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 KXG49063.1 - 0.21 11.3 0.1 0.38 10.4 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 KXG49063.1 - 0.21 11.9 1.4 0.95 9.8 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain HAD PF12710.7 KXG49064.1 - 1.6e-29 103.7 0.0 2.5e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KXG49064.1 - 0.00022 20.7 0.0 0.32 10.4 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.26 KXG49064.1 - 0.014 15.6 0.9 0.06 13.6 0.1 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Phosphorylase PF00343.20 KXG49065.1 - 0 1059.2 0.0 0 1059.0 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase AAA_35 PF14516.6 KXG49065.1 - 0.014 14.2 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain G-alpha PF00503.20 KXG49066.1 - 4.4e-112 374.7 0.3 5.1e-112 374.5 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KXG49066.1 - 3.4e-15 56.0 1.3 3.5e-10 39.6 0.3 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXG49066.1 - 0.0002 20.8 0.1 0.37 10.1 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KXG49066.1 - 0.0056 16.9 0.4 1.1 9.6 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Rota_NS53 PF00981.17 KXG49066.1 - 0.018 14.0 0.5 1.3 7.8 0.2 2.1 2 0 0 2 2 2 0 Rotavirus RNA-binding Protein 53 (NS53) MCM PF00493.23 KXG49066.1 - 0.076 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 KXG49066.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.25 KXG49067.1 - 3.5e-67 226.6 0.0 4.6e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG49067.1 - 1e-31 110.2 0.0 1.3e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXG49067.1 - 1.1e-05 24.6 0.1 1.5e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXG49067.1 - 0.00015 21.1 0.1 0.00053 19.4 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXG49067.1 - 0.00054 19.4 0.0 0.046 13.0 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 KXG49067.1 - 0.00098 19.1 0.0 0.0024 17.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KXG49067.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KXG49067.1 - 0.047 13.3 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.9 KXG49068.1 - 2.4e-138 461.0 0.0 3.2e-138 460.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 KXG49068.1 - 8.4e-07 28.9 0.1 0.008 16.1 0.0 2.5 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 KXG49068.1 - 5.9e-05 22.8 1.0 0.00092 18.9 0.0 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Uds1 PF15456.6 KXG49068.1 - 0.25 11.5 4.3 1.3 9.2 4.7 2.0 2 0 0 2 2 2 0 Up-regulated During Septation Cullin PF00888.22 KXG49069.1 - 1.4e-192 641.6 13.4 1.9e-192 641.2 13.4 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KXG49069.1 - 9.6e-27 92.8 4.9 1.4e-26 92.3 3.4 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain AMP-binding PF00501.28 KXG49070.1 - 8.3e-134 446.3 0.1 8.4e-68 228.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.12 KXG49070.1 - 3.9e-38 131.1 0.0 1.1e-37 129.6 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Condensation PF00668.20 KXG49070.1 - 6.3e-31 107.5 0.0 1.5e-30 106.3 0.0 1.6 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KXG49070.1 - 8.8e-15 54.8 2.8 4.6e-06 26.9 0.1 3.7 4 0 0 4 4 4 2 Phosphopantetheine attachment site Epimerase PF01370.21 KXG49070.1 - 5.5e-07 29.3 0.0 1.5e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 KXG49070.1 - 0.00016 22.6 0.0 0.02 15.9 0.0 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 KXG49070.1 - 0.003 16.6 0.3 0.11 11.5 0.0 2.4 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KXG49070.1 - 0.078 13.4 0.0 1.3 9.4 0.0 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KXG49071.1 - 5.5e-22 78.5 0.0 7.7e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG49071.1 - 1.5e-09 38.0 0.0 2.1e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Methyltransf_2 PF00891.18 KXG49072.1 - 4.6e-20 71.8 0.0 5e-19 68.4 0.0 2.0 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 KXG49072.1 - 0.013 15.5 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_33 PF10017.9 KXG49072.1 - 0.013 14.7 0.0 0.085 12.0 0.0 2.0 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent p450 PF00067.22 KXG49073.1 - 4.9e-33 114.6 0.0 6.2e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CotJA PF11007.8 KXG49073.1 - 0.12 12.2 1.0 0.45 10.4 0.0 2.4 3 0 0 3 3 3 0 Spore coat associated protein JA (CotJA) FAD_binding_3 PF01494.19 KXG49074.1 - 1.5e-12 47.5 0.9 1.2e-11 44.4 0.9 2.3 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KXG49074.1 - 8.1e-07 28.5 0.1 1.3e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG49074.1 - 1.8e-05 24.1 0.1 0.0089 15.3 0.1 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG49074.1 - 0.0003 20.5 0.9 0.13 11.8 0.3 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KXG49074.1 - 0.0006 18.6 0.1 0.0013 17.6 0.1 1.6 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KXG49074.1 - 0.0018 18.4 0.1 0.0061 16.8 0.1 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXG49074.1 - 0.0046 16.1 0.0 0.0071 15.5 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXG49074.1 - 0.0047 16.3 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXG49074.1 - 0.029 13.7 0.1 0.052 12.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KXG49074.1 - 0.25 10.4 0.5 1.2 8.2 0.1 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein p450 PF00067.22 KXG49075.1 - 3.6e-62 210.6 0.0 4.3e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXG49076.1 - 8.3e-59 199.5 0.0 6.4e-58 196.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 KXG49077.1 - 2.1e-33 115.8 0.0 2.7e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG49077.1 - 8.3e-12 45.4 0.2 1.2e-11 44.8 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXG49077.1 - 0.0002 20.9 0.1 0.018 14.5 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXG49077.1 - 0.0016 17.5 0.0 0.48 9.4 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KXG49077.1 - 0.0071 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KXG49077.1 - 0.0084 16.7 0.1 0.022 15.4 0.1 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KXG49077.1 - 0.042 14.1 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain PALP PF00291.25 KXG49077.1 - 0.048 13.1 0.1 0.073 12.5 0.1 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme p450 PF00067.22 KXG49078.1 - 8e-38 130.4 0.0 1.6e-37 129.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 KXG49078.1 - 4.8e-29 101.6 0.0 7.3e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG49078.1 - 3e-10 40.3 0.0 5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXG49078.1 - 0.095 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 KXG49078.1 - 0.12 12.2 0.1 0.38 10.7 0.1 1.7 2 0 0 2 2 2 0 KR domain DapB_N PF01113.20 KXG49078.1 - 0.14 12.3 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus FAD_binding_4 PF01565.23 KXG49079.1 - 4e-19 68.7 3.9 8.3e-19 67.7 3.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG49079.1 - 0.00076 19.5 0.3 0.0027 17.8 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like LacI PF00356.21 KXG49079.1 - 0.0062 16.3 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Trp_DMAT PF11991.8 KXG49080.1 - 1.9e-95 320.4 0.1 2.2e-95 320.1 0.1 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Trp_DMAT PF11991.8 KXG49081.1 - 1.1e-94 317.9 0.0 1.3e-94 317.6 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase adh_short_C2 PF13561.6 KXG49082.1 - 6.7e-25 88.0 0.0 8.4e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG49082.1 - 1.5e-18 67.0 0.0 2e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG49082.1 - 0.00039 20.4 0.0 0.00057 19.9 0.0 1.2 1 0 0 1 1 1 1 KR domain ATP_bind_2 PF03668.15 KXG49082.1 - 0.075 12.3 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 P-loop ATPase protein family ATP-grasp_5 PF13549.6 KXG49082.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain LDcluster4 PF18306.1 KXG49082.1 - 0.12 12.0 1.1 0.18 11.4 0.2 1.7 2 0 0 2 2 2 0 SLOG cluster4 family Cupin_1 PF00190.22 KXG49083.1 - 1.6e-06 27.8 0.0 2.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KXG49083.1 - 2.2e-06 27.2 0.5 9.4e-06 25.3 0.1 2.0 2 1 1 3 3 3 1 Cupin domain ARD PF03079.14 KXG49083.1 - 0.0037 17.5 0.0 0.0056 16.9 0.0 1.4 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.7 KXG49083.1 - 0.0067 16.2 0.0 0.0082 15.9 0.0 1.1 1 0 0 1 1 1 1 Cupin MARVEL PF01284.23 KXG49084.1 - 0.27 11.3 4.5 0.44 10.6 4.5 1.3 1 0 0 1 1 1 0 Membrane-associating domain Mit_KHE1 PF10173.9 KXG49085.1 - 5.8e-61 205.9 0.3 5.8e-61 205.9 0.3 1.5 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related ABC2_membrane_4 PF12730.7 KXG49085.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein End3 PF12761.7 KXG49086.1 - 3e-67 226.7 0.2 4.4e-67 226.1 0.2 1.3 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KXG49086.1 - 8.1e-51 170.3 0.2 1.3e-47 160.0 0.2 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KXG49086.1 - 3.8e-08 32.3 0.2 2.6e-07 29.7 0.3 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KXG49086.1 - 1.8e-06 28.3 0.2 1.3e-05 25.6 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KXG49086.1 - 6.3e-05 22.6 0.2 0.00064 19.5 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KXG49086.1 - 0.0017 18.2 0.0 0.0043 16.9 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXG49086.1 - 0.0018 17.6 0.2 0.0081 15.6 0.2 2.1 1 0 0 1 1 1 1 EF hand DUF4407 PF14362.6 KXG49086.1 - 0.28 10.5 2.2 0.4 10.0 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 KXG49086.1 - 0.36 11.5 3.0 14 6.4 0.1 2.9 2 0 0 2 2 2 0 SlyX DUF4201 PF13870.6 KXG49086.1 - 1.8 8.3 8.3 0.66 9.7 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.12 KXG49086.1 - 3.2 7.8 8.4 1.9 8.6 1.0 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KXG49086.1 - 8.1 5.2 9.5 0.93 8.3 3.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Pectate_lyase PF03211.13 KXG49087.1 - 4.6e-77 258.2 7.5 5.5e-77 257.9 7.5 1.0 1 0 0 1 1 1 1 Pectate lyase SNF2_N PF00176.23 KXG49088.1 - 1e-62 211.9 0.1 2.4e-62 210.7 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXG49088.1 - 6.7e-24 84.4 0.4 4.7e-22 78.4 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KXG49088.1 - 2.1e-07 30.4 0.0 1e-05 24.9 0.0 2.7 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KXG49088.1 - 3e-06 27.4 0.0 1.1e-05 25.5 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DSPc PF00782.20 KXG49090.1 - 1.5e-12 47.5 0.1 2.2e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KXG49090.1 - 0.0029 17.9 0.1 0.0049 17.1 0.1 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain UPF0492 PF15744.5 KXG49090.1 - 0.089 12.0 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 Abhydrolase_1 PF00561.20 KXG49091.1 - 8.3e-22 78.1 0.0 1.4e-20 74.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KXG49091.1 - 8.6e-18 64.4 0.0 2.1e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Aldo_ket_red PF00248.21 KXG49093.1 - 1.1e-51 175.8 0.0 1.5e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family EamA PF00892.20 KXG49093.1 - 1e-10 41.9 24.9 2.4e-05 24.5 1.8 2.5 2 0 0 2 2 2 2 EamA-like transporter family CSG2 PF16965.5 KXG49093.1 - 3e-07 29.7 4.6 3e-07 29.7 4.6 2.0 2 1 0 2 2 2 1 Ceramide synthase regulator Nuc_sug_transp PF04142.15 KXG49093.1 - 0.0057 15.9 0.1 0.0057 15.9 0.1 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter DUF202 PF02656.15 KXG49093.1 - 0.046 14.2 0.4 0.046 14.2 0.4 4.1 5 1 0 5 5 5 0 Domain of unknown function (DUF202) Tubulin PF00091.25 KXG49095.1 - 1.2e-68 231.2 0.0 2e-68 230.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXG49095.1 - 2.8e-43 147.1 0.3 5.2e-43 146.2 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KXG49095.1 - 3.3e-08 33.9 0.0 6.9e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KXG49095.1 - 0.068 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain DUF1754 PF08555.10 KXG49096.1 - 5.4e-13 49.6 19.1 8.8e-13 48.9 19.1 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) CDC27 PF09507.10 KXG49096.1 - 0.028 13.8 17.6 0.032 13.6 17.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Dsh_C PF12316.8 KXG49096.1 - 0.65 10.4 5.1 0.85 10.0 5.1 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CAML PF14963.6 KXG49096.1 - 1.4 9.0 7.0 1.7 8.7 7.0 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand MCM3AP_GANP PF16769.5 KXG49096.1 - 4 5.6 8.8 4.8 5.3 8.8 1.0 1 0 0 1 1 1 0 MCM3AP domain of GANP Vfa1 PF08432.10 KXG49096.1 - 4.5 7.6 13.9 5.4 7.3 13.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Trypan_PARP PF05887.11 KXG49096.1 - 4.5 7.3 9.9 6.8 6.7 9.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RR_TM4-6 PF06459.12 KXG49096.1 - 6 6.6 14.3 7.1 6.4 14.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KXG49096.1 - 6.1 5.0 16.9 7.1 4.8 16.9 1.0 1 0 0 1 1 1 0 CDC45-like protein HSP70 PF00012.20 KXG49096.1 - 6.8 4.7 10.4 8.4 4.4 10.4 1.0 1 0 0 1 1 1 0 Hsp70 protein PAF-AH_p_II PF03403.13 KXG49097.1 - 1.5e-15 56.6 0.0 3.5e-07 29.1 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KXG49097.1 - 4e-08 32.5 0.4 1.1e-07 31.0 0.2 1.8 2 1 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KXG49097.1 - 0.00064 18.8 0.0 0.015 14.4 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase Abhydrolase_5 PF12695.7 KXG49097.1 - 0.0049 16.7 0.1 3.2 7.5 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG49097.1 - 0.0077 15.9 0.1 0.025 14.2 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG49097.1 - 0.03 14.9 0.2 0.043 14.4 0.2 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG49097.1 - 0.031 13.5 0.0 0.63 9.3 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KXG49097.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) CBM_20 PF00686.19 KXG49098.1 - 6e-33 112.6 0.2 1.1e-32 111.8 0.2 1.4 1 0 0 1 1 1 1 Starch binding domain LPMO_10 PF03067.15 KXG49098.1 - 4.8e-08 33.9 4.9 8.7e-08 33.0 3.8 2.1 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading PTPA PF03095.15 KXG49099.1 - 4e-108 361.4 0.0 4.7e-108 361.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF202 PF02656.15 KXG49100.1 - 8e-22 77.5 0.7 8e-22 77.5 0.7 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KXG49100.1 - 4.4 7.1 11.4 6.2 6.6 11.4 1.1 1 0 0 1 1 1 0 SPX domain Actin PF00022.19 KXG49101.1 - 7.7e-111 370.6 0.0 5.2e-110 367.9 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXG49101.1 - 0.0051 15.7 0.0 0.026 13.3 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein BBS2_Mid PF14783.6 KXG49101.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region NAD_binding_2 PF03446.15 KXG49102.1 - 3e-27 95.7 0.0 4.9e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXG49102.1 - 1.2e-14 54.5 0.2 3e-14 53.3 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KXG49102.1 - 0.00074 20.1 0.0 0.0027 18.2 0.0 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IMPDH PF00478.25 KXG49102.1 - 0.054 12.5 0.8 1.2 8.1 0.3 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain 2-Hacid_dh_C PF02826.19 KXG49102.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Zemlya PF17646.1 KXG49102.1 - 0.15 12.4 0.2 0.78 10.1 0.1 2.0 2 0 0 2 2 2 0 Closterovirus 1a polyprotein central region GTP_cyclohydro2 PF00925.20 KXG49103.1 - 1.4e-58 197.1 0.1 7.5e-58 194.7 0.0 1.9 2 0 0 2 2 2 1 GTP cyclohydrolase II DUF3425 PF11905.8 KXG49103.1 - 3.1e-23 82.1 1.0 5.1e-23 81.4 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KXG49103.1 - 0.033 14.3 5.6 0.099 12.8 5.6 1.8 1 1 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KXG49103.1 - 2.3 8.4 7.1 22 5.2 7.1 2.2 1 1 0 1 1 1 0 Basic region leucine zipper DUF1325 PF07039.11 KXG49104.1 - 7.6e-35 119.9 0.0 1.4e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.10 KXG49104.1 - 0.051 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Tudor_3 PF18115.1 KXG49104.1 - 0.077 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KXG49104.1 - 0.15 12.1 0.1 0.38 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) PMI_typeI PF01238.21 KXG49105.1 - 1.1e-148 495.5 0.0 1.3e-148 495.2 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KXG49105.1 - 0.00085 19.0 0.2 0.042 13.6 0.1 2.3 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 KXG49105.1 - 0.0096 15.8 0.0 0.72 9.8 0.0 2.6 2 0 0 2 2 2 1 AraC-like ligand binding domain NPHI_C PF08469.10 KXG49105.1 - 0.026 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal Abhydrolase_3 PF07859.13 KXG49106.1 - 3.5e-26 92.4 0.0 4.6e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXG49106.1 - 8e-23 80.9 0.0 1.1e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KXG49106.1 - 0.0087 15.6 0.0 0.026 14.0 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2974 PF11187.8 KXG49106.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Coatomer_E PF04733.14 KXG49107.1 - 2.7e-61 207.5 3.1 3.1e-61 207.3 3.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KXG49107.1 - 1.2e-11 45.0 14.6 0.00095 19.6 0.9 4.5 2 1 2 4 4 4 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG49107.1 - 1.3e-08 35.0 1.5 0.00079 19.6 0.7 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KXG49107.1 - 2.5e-08 34.4 10.9 0.0029 18.2 3.4 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXG49107.1 - 3.8e-07 30.3 5.0 0.0073 16.9 0.4 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXG49107.1 - 2.7e-06 27.7 12.6 0.22 12.4 0.8 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 KXG49107.1 - 3.3e-05 24.1 17.1 0.029 15.0 0.2 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXG49107.1 - 3.8e-05 23.5 11.0 0.15 12.3 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXG49107.1 - 0.00045 20.4 11.8 0.79 10.1 4.2 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXG49107.1 - 0.0017 18.1 3.5 1.8 8.5 0.0 4.9 6 0 0 6 6 5 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KXG49107.1 - 0.036 14.1 0.0 0.09 12.8 0.0 1.7 1 0 0 1 1 1 0 Putative TPR-like repeat Type_III_YscG PF09477.10 KXG49107.1 - 0.04 14.0 4.7 1.4 9.0 1.3 3.2 1 1 1 3 3 3 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_9 PF13371.6 KXG49107.1 - 0.042 14.0 4.1 31 4.8 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KXG49107.1 - 0.067 13.1 4.4 0.26 11.2 0.8 2.7 1 1 2 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal PYRIN PF02758.16 KXG49107.1 - 0.072 13.3 0.5 7.1 6.9 0.1 2.5 1 1 1 2 2 2 0 PAAD/DAPIN/Pyrin domain TPR_15 PF13429.6 KXG49107.1 - 0.14 11.4 9.6 0.38 9.9 2.5 3.1 1 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KXG49107.1 - 0.36 11.2 7.3 3 8.3 2.3 3.4 2 1 2 4 4 4 0 Bacterial transcriptional activator domain TPR_17 PF13431.6 KXG49107.1 - 0.42 11.1 2.7 1e+02 3.6 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.7 KXG49107.1 - 0.47 10.7 5.2 0.36 11.1 2.1 2.3 2 1 0 2 2 2 0 Tetratrico peptide repeat TPR_20 PF14561.6 KXG49107.1 - 3.4 8.1 14.6 0.13 12.6 2.5 3.6 4 1 1 5 5 3 0 Tetratricopeptide repeat A_deaminase PF00962.22 KXG49109.1 - 1.3e-21 77.3 0.0 2.2e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase RVT_1 PF00078.27 KXG49109.1 - 0.00033 20.2 0.0 0.00068 19.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pox_A_type_inc PF04508.12 KXG49109.1 - 0.21 11.5 2.6 23 5.1 0.1 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat MFS_1 PF07690.16 KXG49110.1 - 3e-40 138.2 43.6 6.1e-40 137.2 42.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG49110.1 - 1.1e-11 43.9 18.2 1.8e-11 43.2 18.2 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_3 PF01494.19 KXG49112.1 - 2.3e-19 69.9 0.0 1.5e-18 67.1 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG49112.1 - 4.7e-05 22.8 0.0 0.0055 16.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG49112.1 - 5.8e-05 23.2 0.1 0.00025 21.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXG49112.1 - 0.00032 20.1 0.0 0.017 14.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXG49112.1 - 0.028 13.5 0.1 0.87 8.6 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.17 KXG49112.1 - 0.033 13.4 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family SE PF08491.10 KXG49112.1 - 0.033 13.2 0.0 0.18 10.8 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox PF00070.27 KXG49112.1 - 0.037 14.6 0.0 0.33 11.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG49112.1 - 0.051 12.7 0.0 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KXG49112.1 - 0.089 12.4 0.2 1.3 8.6 0.1 2.1 1 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXG49112.1 - 0.18 11.7 0.6 19 5.2 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding DIOX_N PF14226.6 KXG49113.1 - 9.4e-26 90.9 0.0 1.6e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG49113.1 - 3.4e-17 62.8 0.0 6.1e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_4 PF01565.23 KXG49114.1 - 2.2e-24 85.8 1.0 4.1e-24 84.9 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG49114.1 - 4.7e-13 49.0 0.4 9.7e-13 48.0 0.4 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KXG49114.1 - 0.058 12.8 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.23 KXG49115.1 - 3e-20 72.4 0.2 6.6e-20 71.3 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG49115.1 - 2.5e-06 27.5 0.5 5.8e-06 26.3 0.5 1.6 1 0 0 1 1 1 1 Berberine and berberine like ketoacyl-synt PF00109.26 KXG49116.1 - 1.1e-75 254.5 0.0 2.3e-75 253.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 KXG49116.1 - 2.5e-74 250.4 0.0 7.9e-74 248.7 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 KXG49116.1 - 1.2e-62 212.2 0.0 2e-62 211.3 0.0 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 KXG49116.1 - 9.5e-55 185.3 0.5 1.5e-52 178.2 0.0 3.6 4 0 0 4 4 4 1 KR domain PS-DH PF14765.6 KXG49116.1 - 6.3e-47 160.2 0.0 1.1e-46 159.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXG49116.1 - 3.6e-41 141.7 0.1 7.5e-41 140.7 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXG49116.1 - 7.5e-28 96.9 0.0 2.1e-27 95.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KXG49116.1 - 7.1e-25 87.6 0.0 2.8e-24 85.7 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KXG49116.1 - 3.2e-20 72.2 0.1 1.3e-09 38.3 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KXG49116.1 - 1.4e-16 61.0 0.0 5.3e-16 59.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXG49116.1 - 9.5e-15 55.0 0.0 3.2e-14 53.3 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KXG49116.1 - 1.4e-11 44.9 0.0 6.6e-10 39.6 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.21 KXG49116.1 - 3.5e-11 43.0 0.0 3.3e-07 30.0 0.0 2.7 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXG49116.1 - 3.7e-11 42.6 0.0 1.7e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.6 KXG49116.1 - 4e-11 42.9 0.0 2.1e-09 37.3 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG49116.1 - 1.3e-10 41.3 0.0 4.5e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXG49116.1 - 1.4e-10 40.9 0.0 8.1e-10 38.5 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_11 PF08241.12 KXG49116.1 - 5e-08 33.5 0.0 2.8e-07 31.1 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KXG49116.1 - 0.00016 21.3 0.0 0.00046 19.8 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KXG49116.1 - 0.0011 18.9 0.0 0.49 10.3 0.0 3.8 4 0 0 4 4 4 1 NAD(P)H-binding Thiolase_N PF00108.23 KXG49116.1 - 0.0014 18.1 0.0 0.0029 17.0 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Sacchrp_dh_NADP PF03435.18 KXG49116.1 - 0.017 15.4 0.0 1.1 9.6 0.0 2.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KXG49116.1 - 0.082 12.3 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Ubie_methyltran PF01209.18 KXG49116.1 - 0.16 11.3 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GFO_IDH_MocA PF01408.22 KXG49117.1 - 8.9e-18 65.3 0.0 1.5e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KXG49117.1 - 0.0037 17.7 0.0 0.0066 16.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KXG49117.1 - 0.038 14.7 0.0 0.077 13.7 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NmrA PF05368.13 KXG49118.1 - 1.3e-53 182.0 0.3 1.5e-53 181.7 0.3 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG49118.1 - 1.2e-18 67.7 0.3 1.8e-18 67.1 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXG49118.1 - 1.5e-06 27.4 0.0 3.2e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXG49118.1 - 7.9e-05 22.2 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KXG49118.1 - 0.00039 20.6 0.3 0.0011 19.2 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KXG49118.1 - 0.0013 19.0 0.3 0.0064 16.7 0.1 2.1 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KXG49118.1 - 0.0056 16.1 0.0 0.016 14.6 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 KXG49118.1 - 0.029 14.3 0.1 0.26 11.3 0.1 2.2 1 1 1 2 2 2 0 Zinc-binding dehydrogenase DXP_reductoisom PF02670.16 KXG49118.1 - 0.042 14.5 0.1 0.086 13.6 0.1 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase KR PF08659.10 KXG49118.1 - 0.063 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 KR domain PI-PLC-X PF00388.19 KXG49119.1 - 4.5e-60 201.4 0.0 8.4e-60 200.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KXG49119.1 - 1.2e-43 148.1 0.1 2.6e-42 143.8 0.2 2.5 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_8 PF13833.6 KXG49119.1 - 0.0024 17.7 0.1 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_like PF09279.11 KXG49119.1 - 0.011 16.2 0.0 0.026 15.0 0.0 1.7 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_6 PF13405.6 KXG49119.1 - 0.021 14.7 1.1 0.15 12.1 0.3 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 KXG49119.1 - 0.023 14.2 0.1 0.11 12.0 0.1 2.3 2 0 0 2 2 2 0 EF hand GDPD PF03009.17 KXG49119.1 - 0.049 13.4 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family p25-alpha PF05517.12 KXG49119.1 - 0.081 13.1 0.7 0.62 10.2 0.7 2.3 1 1 1 2 2 2 0 p25-alpha Ndufs5 PF10200.9 KXG49119.1 - 0.16 12.2 0.1 0.41 10.9 0.1 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa EF-hand_7 PF13499.6 KXG49119.1 - 0.18 12.3 1.5 0.84 10.1 0.3 2.5 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 KXG49119.1 - 4.2 7.0 4.9 0.67 9.6 0.2 2.2 3 0 0 3 3 3 0 EF hand Transp_cyt_pur PF02133.15 KXG49120.1 - 3.4e-152 507.3 40.3 3.9e-152 507.1 40.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF543 PF04418.12 KXG49121.1 - 4.1e-28 97.2 0.2 4.8e-28 97.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.9 KXG49122.1 - 9.7e-63 211.8 2.0 4.9e-62 209.5 0.0 2.6 2 0 0 2 2 2 1 Urb2/Npa2 family AvrE_T3Es PF11725.8 KXG49123.1 - 3.2 4.8 5.6 4 4.5 5.6 1.0 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) GST_N_4 PF17172.4 KXG49124.1 - 3.9e-24 85.3 0.1 6.6e-24 84.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KXG49124.1 - 1.1e-19 69.9 0.0 2.4e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KXG49124.1 - 2.3e-14 53.8 0.1 3.8e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 KXG49124.1 - 5.4e-06 26.7 0.1 1.2e-05 25.6 0.0 1.6 2 0 0 2 2 2 1 SAM35, subunit of SAM coomplex GST_C_2 PF13410.6 KXG49124.1 - 0.017 15.1 0.1 0.032 14.2 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_11 PF08241.12 KXG49125.1 - 8.8e-09 35.9 0.0 2.3e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG49125.1 - 1.4e-08 35.3 0.0 3e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG49125.1 - 4.6e-07 29.8 0.0 8.2e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG49125.1 - 1e-06 29.4 0.0 1.9e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG49125.1 - 9.3e-06 25.5 0.0 1.6e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_33 PF10017.9 KXG49125.1 - 0.0014 17.9 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_32 PF13679.6 KXG49125.1 - 0.0043 17.1 0.0 0.0064 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG49125.1 - 0.0045 16.3 0.0 0.0065 15.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXG49125.1 - 0.063 12.8 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain CDC14 PF08045.11 KXG49126.1 - 9e-125 415.5 0.0 1e-124 415.3 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component polyprenyl_synt PF00348.17 KXG49127.1 - 1.1e-65 221.2 0.0 1.4e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF1771 PF08590.10 KXG49128.1 - 8.1e-25 87.0 7.7 8.1e-25 87.0 7.7 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KXG49128.1 - 1.3e-10 41.4 0.2 3.9e-10 39.9 0.2 1.9 1 0 0 1 1 1 1 Smr domain DUF4407 PF14362.6 KXG49128.1 - 0.25 10.6 3.0 0.45 9.8 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KXG49128.1 - 0.32 11.3 8.3 6.1 7.2 3.1 2.5 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) G-alpha PF00503.20 KXG49129.1 - 1.4e-124 415.8 2.8 1.7e-124 415.6 2.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KXG49129.1 - 2.4e-15 56.4 1.6 2.4e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KXG49129.1 - 4e-05 23.4 0.0 0.00018 21.3 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KXG49129.1 - 0.002 17.5 3.8 0.043 13.2 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KXG49129.1 - 0.0047 17.1 1.0 2.4 8.4 0.0 3.3 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KXG49129.1 - 0.014 15.2 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 KXG49129.1 - 0.054 12.6 0.1 0.12 11.5 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 KXG49129.1 - 0.083 12.4 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KXG49129.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KXG49129.1 - 0.14 12.3 0.1 8.9 6.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Use1 PF09753.9 KXG49130.1 - 6e-07 29.4 11.9 1.6e-06 28.1 11.9 1.8 1 1 0 1 1 1 1 Membrane fusion protein Use1 RXT2_N PF08595.11 KXG49130.1 - 0.21 11.6 7.6 0.12 12.4 5.3 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF572 PF04502.13 KXG49130.1 - 3.2 7.3 17.2 4.5 6.8 17.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Uso1_p115_C PF04871.13 KXG49130.1 - 4.2 7.8 17.1 3.4 8.1 1.6 2.6 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Miga PF10265.9 KXG49131.1 - 0.023 13.7 0.1 0.027 13.5 0.1 1.0 1 0 0 1 1 1 0 Mitoguardin AMP-binding PF00501.28 KXG49132.1 - 2.1e-90 303.3 0.0 2.8e-90 303.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG49132.1 - 9.7e-14 52.1 0.2 3e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Nup188_C PF18378.1 KXG49133.1 - 1.2e-140 468.6 5.4 1.8e-140 468.0 5.4 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KXG49133.1 - 3.8e-84 283.3 0.0 9.8e-84 281.9 0.0 1.7 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.21 KXG49134.1 - 1.9e-98 328.7 0.0 5.3e-98 327.2 0.0 1.7 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 KXG49134.1 - 8.5e-57 192.1 0.0 3.6e-55 186.8 0.0 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 KXG49134.1 - 4.9e-47 160.2 0.0 8.3e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXG49134.1 - 2.4e-05 24.2 0.4 6.7e-05 22.7 0.4 1.7 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 KXG49134.1 - 0.0024 17.7 0.2 0.039 13.7 0.0 2.8 4 0 0 4 4 4 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 KXG49134.1 - 0.031 13.7 0.1 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.14 KXG49134.1 - 0.057 12.6 0.1 0.59 9.3 0.0 2.6 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Peripla_BP_2 PF01497.18 KXG49134.1 - 0.076 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein BRCT PF00533.26 KXG49135.1 - 1.8e-07 31.4 0.0 4.2e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KXG49135.1 - 1.4e-05 24.9 0.0 3.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KXG49135.1 - 2.3e-05 24.7 0.0 6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain WGR PF05406.15 KXG49135.1 - 0.00014 21.9 0.1 0.00027 21.0 0.1 1.5 1 0 0 1 1 1 1 WGR domain LIG3_BRCT PF16759.5 KXG49135.1 - 0.03 14.6 0.4 0.21 11.9 0.0 2.3 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Brix PF04427.18 KXG49136.1 - 3.6e-31 108.8 0.0 4.6e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Brix domain UPF1_Zn_bind PF09416.10 KXG49137.1 - 6.1e-72 240.6 2.3 8.4e-72 240.1 1.1 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KXG49137.1 - 5.5e-60 202.4 0.0 1e-59 201.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXG49137.1 - 7.8e-54 183.2 2.5 1.8e-30 106.6 0.2 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KXG49137.1 - 1.4e-32 111.8 0.0 2.6e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KXG49137.1 - 1.7e-13 50.7 0.2 1.6e-12 47.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXG49137.1 - 6e-11 42.9 0.1 2.1e-10 41.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KXG49137.1 - 5e-06 26.6 0.0 9.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KXG49137.1 - 7.8e-05 22.5 0.2 0.41 10.3 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KXG49137.1 - 0.00012 21.4 0.2 0.012 14.9 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KXG49137.1 - 0.0006 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 KXG49137.1 - 0.0029 16.8 0.1 0.56 9.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase UvrD-helicase PF00580.21 KXG49137.1 - 0.0038 16.8 0.0 0.041 13.4 0.1 2.4 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 KXG49137.1 - 0.012 15.4 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase ATPase PF06745.13 KXG49137.1 - 0.055 12.8 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_10 PF12846.7 KXG49137.1 - 0.069 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 KXG49137.1 - 0.14 12.4 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXG49137.1 - 2.7 8.4 4.9 0.73 10.3 0.5 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-C2H2_aberr PF17017.5 KXG49138.1 - 1.7e-07 31.5 0.3 1.7e-07 31.5 0.3 1.5 2 0 0 2 2 2 1 Aberrant zinc-finger zf-C2H2 PF00096.26 KXG49138.1 - 3.6e-05 24.0 16.5 0.4 11.2 3.7 3.8 3 1 0 3 3 3 3 Zinc finger, C2H2 type Cnn_1N PF07989.11 KXG49138.1 - 0.00099 19.2 0.2 0.0089 16.2 0.2 2.2 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 zf-C2H2_4 PF13894.6 KXG49138.1 - 0.066 14.1 8.9 18 6.5 0.6 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger Trimer_CC PF08954.11 KXG49138.1 - 0.072 12.7 4.8 0.17 11.5 4.8 1.6 1 0 0 1 1 1 0 Trimerisation motif Transpos_assoc PF13963.6 KXG49138.1 - 0.11 12.8 0.3 0.11 12.8 0.3 2.1 1 1 0 2 2 2 0 Transposase-associated domain zf-H2C2_2 PF13465.6 KXG49138.1 - 4.5 7.9 14.3 5.6 7.6 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Methyltransf_34 PF11312.8 KXG49139.1 - 2e-101 339.3 0.0 2.5e-101 339.0 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase CEND1 PF15677.5 KXG49139.1 - 0.9 10.1 7.3 2.1 8.9 7.3 1.5 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Band_7 PF01145.25 KXG49140.1 - 3.2e-24 85.9 8.3 7.6e-24 84.7 8.3 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KXG49140.1 - 0.00022 20.4 3.0 0.00029 20.0 3.0 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial UcrQ PF02939.16 KXG49141.1 - 1.2e-33 114.8 0.2 1.4e-33 114.6 0.2 1.1 1 0 0 1 1 1 1 UcrQ family Spermine_synth PF01564.17 KXG49142.1 - 3.3e-73 245.1 0.0 4.4e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KXG49142.1 - 1.3e-23 82.6 0.1 2.2e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KXG49142.1 - 1.9e-05 25.3 0.0 5.1e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG49142.1 - 0.00016 22.3 0.2 0.0018 18.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXG49142.1 - 0.037 13.6 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 KXG49142.1 - 0.098 12.6 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.24 KXG49143.1 - 1e-82 278.4 21.1 1.2e-82 278.2 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG49143.1 - 1e-13 51.0 52.5 1.4e-12 47.2 27.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FMN_dh PF01070.18 KXG49144.1 - 2.7e-118 395.0 0.0 3.1e-118 394.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXG49144.1 - 0.00024 20.2 1.0 0.00043 19.4 1.0 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXG49144.1 - 0.00059 19.1 0.1 0.00088 18.5 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KXG49144.1 - 0.00089 18.7 0.6 0.0012 18.3 0.6 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KXG49144.1 - 0.001 18.4 0.9 0.54 9.5 0.4 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KXG49144.1 - 0.025 14.1 0.2 0.35 10.3 0.0 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein Gpr1_Fun34_YaaH PF01184.19 KXG49145.1 - 1.7e-84 282.5 13.3 2e-84 282.3 13.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family HisKA_4TM PF16926.5 KXG49145.1 - 0.056 13.0 0.1 0.096 12.2 0.1 1.3 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase DUF745 PF05335.13 KXG49147.1 - 0.001 18.8 0.0 0.0013 18.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF745) Helo_like_N PF17111.5 KXG49147.1 - 0.0022 17.4 0.1 0.016 14.6 0.1 2.2 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins Med9 PF07544.13 KXG49147.1 - 0.011 15.8 0.1 0.018 15.2 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Atg14 PF10186.9 KXG49147.1 - 0.023 13.8 0.2 0.027 13.5 0.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Syntaxin PF00804.25 KXG49147.1 - 0.03 14.0 0.8 2.1 8.0 0.2 2.1 1 1 1 2 2 2 0 Syntaxin CortBP2 PF09727.9 KXG49147.1 - 0.037 13.9 0.1 0.045 13.7 0.1 1.1 1 0 0 1 1 1 0 Cortactin-binding protein-2 PLU-1 PF08429.11 KXG49147.1 - 0.066 12.4 0.0 0.095 11.9 0.0 1.3 1 0 0 1 1 1 0 PLU-1-like protein Lectin_N PF03954.14 KXG49147.1 - 0.12 12.1 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain 3HCDH_N PF02737.18 KXG49148.1 - 3.3e-26 92.3 0.0 5e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXG49148.1 - 4.8e-11 43.1 0.2 1.5e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KXG49148.1 - 0.05 13.8 0.0 0.091 12.9 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Transketolase_N PF00456.21 KXG49149.1 - 4.6e-149 495.9 0.1 6.2e-149 495.5 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KXG49149.1 - 3.8e-44 150.5 0.0 6.8e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXG49149.1 - 9.4e-12 44.9 0.0 2e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KXG49149.1 - 0.00035 19.9 0.0 0.00051 19.3 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KXG49149.1 - 0.0065 15.5 0.1 0.011 14.7 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component FAD_binding_3 PF01494.19 KXG49150.1 - 4.1e-78 263.1 0.0 9.1e-77 258.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXG49150.1 - 4.5e-36 124.4 0.0 8.1e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KXG49150.1 - 4.2e-05 22.4 0.0 6.3e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KXG49150.1 - 7e-05 23.0 0.1 0.00019 21.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXG49150.1 - 7.4e-05 22.1 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXG49150.1 - 0.00023 20.5 0.0 0.0019 17.5 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG49150.1 - 0.0012 18.0 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXG49150.1 - 0.0015 18.2 0.1 0.0035 17.0 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXG49150.1 - 0.0019 17.5 0.2 0.042 13.1 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXG49150.1 - 0.004 16.5 0.0 0.007 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXG49150.1 - 0.0058 15.8 0.0 0.0078 15.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KXG49150.1 - 0.027 15.0 0.0 0.065 13.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KXG49150.1 - 0.048 12.7 0.0 0.1 11.6 0.0 1.5 1 1 0 1 1 1 0 Squalene epoxidase AlaDh_PNT_C PF01262.21 KXG49150.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sugar_tr PF00083.24 KXG49151.1 - 2.4e-138 461.8 18.1 2.8e-138 461.6 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG49151.1 - 7.8e-27 94.1 42.8 5.3e-20 71.7 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXG49151.1 - 7.6e-08 31.3 19.4 6.6e-07 28.2 2.0 2.9 2 2 0 3 3 3 2 MFS/sugar transport protein Pox_A14 PF05767.12 KXG49151.1 - 0.33 11.1 6.0 1.1 9.5 0.0 3.8 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 DUF3533 PF12051.8 KXG49152.1 - 1.2e-84 284.4 13.6 1.6e-84 284.0 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF5488 PF17590.2 KXG49152.1 - 0.022 14.5 0.2 0.063 13.0 0.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5488) Flavin_Reduct PF01613.18 KXG49153.1 - 2.4e-19 69.9 0.0 3.1e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain UbiD PF01977.16 KXG49154.1 - 1e-118 396.8 0.0 1.4e-118 396.3 0.0 1.2 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF4423 PF14394.6 KXG49154.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Fungal_trans PF04082.18 KXG49155.1 - 4.7e-14 52.1 1.3 1.6e-13 50.3 0.6 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cep3 PF16846.5 KXG49155.1 - 0.00084 17.9 0.0 0.0013 17.3 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B Flavoprotein PF02441.19 KXG49156.1 - 1.2e-24 86.9 0.0 1.5e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Fungal_trans PF04082.18 KXG49157.1 - 9.5e-33 113.4 0.0 1.8e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG49157.1 - 1e-08 35.1 14.7 1.7e-08 34.4 14.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 KXG49157.1 - 0.03 14.4 0.2 0.079 13.1 0.2 1.7 1 0 0 1 1 1 0 bZIP transcription factor DUF4635 PF15466.6 KXG49157.1 - 0.085 12.4 0.4 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) SET PF00856.28 KXG49158.1 - 0.0022 18.4 0.0 0.0054 17.1 0.0 1.7 2 0 0 2 2 2 1 SET domain MMR_HSR1_C PF08438.10 KXG49160.1 - 1.4e-36 125.5 0.0 2.4e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KXG49160.1 - 3.9e-08 33.4 0.0 8.9e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miff PF05644.11 KXG49162.1 - 0.052 13.2 0.8 0.21 11.2 0.3 1.9 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff Ribosomal_L7Ae PF01248.26 KXG49163.1 - 8.6e-19 67.1 1.7 8.6e-19 67.1 1.7 2.6 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MAD PF05557.13 KXG49164.1 - 2e-57 195.1 73.2 1.9e-48 165.4 73.9 2.2 2 0 0 2 2 2 2 Mitotic checkpoint protein Tropomyosin_1 PF12718.7 KXG49164.1 - 0.0041 17.3 25.6 0.0041 17.3 25.6 6.8 4 2 2 6 6 6 2 Tropomyosin like Glyco_trans_1_3 PF13528.6 KXG49164.1 - 0.016 14.5 0.7 0.036 13.3 0.7 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF5320 PF17253.2 KXG49164.1 - 0.046 14.8 0.1 0.046 14.8 0.1 7.5 5 3 3 8 8 8 0 Family of unknown function (DUF5320) Flp_N PF03930.14 KXG49164.1 - 0.078 13.0 0.2 0.3 11.1 0.2 2.2 1 0 0 1 1 1 0 Recombinase Flp protein N-terminus Epimerase PF01370.21 KXG49165.1 - 1e-11 44.8 0.1 1.7e-11 44.1 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXG49165.1 - 1.8e-10 40.8 1.2 3.3e-10 39.9 1.2 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG49165.1 - 9.3e-10 38.7 0.5 1.3e-09 38.2 0.5 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KXG49165.1 - 2.2e-07 30.3 0.2 3e-07 29.8 0.2 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KXG49165.1 - 1.5e-06 27.4 0.0 2.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXG49165.1 - 2.4e-05 23.6 0.1 0.14 11.3 0.1 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXG49165.1 - 3.7e-05 23.3 0.1 0.028 13.8 0.1 2.4 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXG49165.1 - 0.0017 17.8 0.2 0.0062 16.0 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase DUF2845 PF11006.8 KXG49165.1 - 0.018 15.1 0.0 0.47 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2845) NAD_binding_4 PF07993.12 KXG49165.1 - 0.034 13.3 0.1 0.11 11.6 0.1 1.8 1 1 1 2 2 2 0 Male sterility protein KR PF08659.10 KXG49165.1 - 0.034 14.0 1.0 0.12 12.2 0.3 2.1 2 1 1 3 3 3 0 KR domain DapB_N PF01113.20 KXG49165.1 - 0.044 13.9 0.1 0.44 10.7 0.1 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Fungal_trans PF04082.18 KXG49166.1 - 5e-05 22.5 0.1 6.5e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2OG-FeII_Oxy PF03171.20 KXG49167.1 - 9.2e-13 48.5 0.0 2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXG49167.1 - 3.3e-10 40.7 0.0 7.5e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Ribonuc_L-PSP PF01042.21 KXG49168.1 - 5.3e-23 81.3 0.0 6.5e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF5130 PF17174.4 KXG49168.1 - 0.015 15.5 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5130) HpcH_HpaI PF03328.14 KXG49169.1 - 2.9e-32 111.6 0.3 3.6e-32 111.3 0.3 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 KXG49169.1 - 0.00055 19.1 0.1 0.015 14.5 0.1 2.5 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain MFS_1 PF07690.16 KXG49170.1 - 6.4e-39 133.9 17.5 6.4e-39 133.9 17.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily adh_short_C2 PF13561.6 KXG49171.1 - 2.4e-47 161.5 1.9 2.8e-47 161.3 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG49171.1 - 6.6e-46 156.2 2.0 8.5e-46 155.9 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG49171.1 - 1.3e-12 48.0 1.1 1.9e-12 47.4 1.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXG49171.1 - 2.2e-05 24.4 0.8 4.4e-05 23.4 0.8 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXG49171.1 - 0.00015 21.0 0.2 0.00019 20.7 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KXG49171.1 - 0.00036 20.8 0.2 0.00053 20.3 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXG49171.1 - 0.00052 19.6 0.5 0.0013 18.3 0.5 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG49171.1 - 0.00063 19.2 0.3 0.0011 18.5 0.3 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Ldh_1_N PF00056.23 KXG49171.1 - 0.039 14.1 0.5 0.082 13.0 0.5 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KXG49171.1 - 0.062 13.4 0.6 0.14 12.2 0.6 1.8 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF1411 PF07199.11 KXG49171.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) NAD_binding_10 PF13460.6 KXG49173.1 - 5.1e-13 49.3 0.0 2.5e-12 47.1 0.0 2.1 1 1 1 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KXG49173.1 - 4.3e-11 42.8 0.0 6.4e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 KXG49173.1 - 0.00042 20.8 0.0 0.0051 17.4 0.0 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KXG49173.1 - 0.0073 15.8 0.0 0.082 12.4 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family LpxI_N PF17930.1 KXG49173.1 - 0.033 14.1 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 LpxI N-terminal domain NAD_binding_7 PF13241.6 KXG49173.1 - 0.11 12.9 0.0 0.36 11.3 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KXG49173.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_transf_4 PF13439.6 KXG49173.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Mpv17_PMP22 PF04117.12 KXG49174.1 - 4.8e-10 39.5 0.1 2.2e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family Chal_sti_synt_N PF00195.19 KXG49175.1 - 6.8e-16 58.4 0.1 9.7e-16 57.9 0.1 1.1 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.12 KXG49175.1 - 0.0031 16.9 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein DUF742 PF05331.11 KXG49175.1 - 0.018 14.8 0.1 0.034 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF742) Thiolase_N PF00108.23 KXG49175.1 - 0.026 13.9 1.8 0.032 13.6 0.2 1.8 2 0 0 2 2 2 0 Thiolase, N-terminal domain Methyltransf_25 PF13649.6 KXG49176.1 - 3.8e-22 78.8 0.0 2.9e-21 76.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG49176.1 - 1.1e-17 64.2 0.0 2.5e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG49176.1 - 9.6e-15 55.0 0.1 2.9e-14 53.5 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG49176.1 - 2.8e-11 43.2 0.0 6.8e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family SET PF00856.28 KXG49176.1 - 6.3e-10 39.7 0.0 1e-09 39.0 0.0 1.5 1 1 0 1 1 1 1 SET domain Methyltransf_12 PF08242.12 KXG49176.1 - 1e-08 35.8 0.0 2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG49176.1 - 6.6e-08 32.6 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXG49176.1 - 3.6e-06 26.6 0.0 6.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXG49176.1 - 0.00011 21.8 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_8 PF05148.15 KXG49176.1 - 0.0021 17.9 0.0 0.055 13.3 0.0 2.3 2 0 0 2 2 2 1 Hypothetical methyltransferase DUF938 PF06080.12 KXG49176.1 - 0.0026 17.6 0.0 0.0063 16.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF938) CMAS PF02353.20 KXG49176.1 - 0.031 13.6 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 KXG49176.1 - 0.032 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Pox_MCEL PF03291.16 KXG49176.1 - 0.048 12.8 0.0 3.5 6.7 0.0 2.2 2 0 0 2 2 2 0 mRNA capping enzyme MetW PF07021.12 KXG49176.1 - 0.049 13.2 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW UPF0020 PF01170.18 KXG49176.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TehB PF03848.14 KXG49176.1 - 0.17 11.2 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB zf-C6H2 PF15801.5 KXG49176.1 - 1.6 9.1 5.7 4.5 7.6 5.7 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding CBM-like PF14683.6 KXG49177.1 - 2.6e-29 102.2 0.1 5.8e-29 101.1 0.1 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KXG49177.1 - 1.1e-27 95.6 0.2 2.9e-27 94.2 0.2 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KXG49177.1 - 7.6e-07 29.3 0.2 2.6e-06 27.6 0.2 1.9 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 KXG49177.1 - 0.0012 19.0 0.0 0.03 14.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) Hydrophobin PF01185.18 KXG49178.1 - 1e-08 35.7 11.2 1.3e-08 35.4 11.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Ferric_reduct PF01794.19 KXG49179.1 - 4.4e-23 81.8 15.5 7.8e-23 81.0 15.5 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXG49179.1 - 3.2e-11 43.6 0.0 5.7e-06 26.5 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXG49179.1 - 1.2e-10 41.5 0.0 0.00043 20.3 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KXG49179.1 - 0.0076 16.9 0.0 0.015 16.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ppx-GppA PF02541.16 KXG49180.1 - 2.9e-43 148.3 0.0 8.9e-43 146.7 0.0 1.6 1 1 0 1 1 1 1 Ppx/GppA phosphatase family Ferrochelatase PF00762.19 KXG49180.1 - 0.046 12.8 0.1 0.096 11.7 0.1 1.4 1 0 0 1 1 1 0 Ferrochelatase DUF3578 PF12102.8 KXG49180.1 - 0.16 11.5 0.1 0.55 9.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3578) AMP-binding PF00501.28 KXG49181.1 - 3.1e-104 348.9 0.0 3.6e-104 348.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG49181.1 - 2.5e-12 47.6 0.0 6.3e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyr_redox_2 PF07992.14 KXG49182.1 - 1.1e-26 93.7 0.0 2e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG49182.1 - 8.7e-16 58.3 0.3 1.3e-13 51.3 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG49182.1 - 0.0006 19.1 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXG49182.1 - 0.00065 19.4 1.6 0.28 10.7 0.1 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXG49182.1 - 0.0062 15.8 0.0 0.04 13.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase PQQ_2 PF13360.6 KXG49182.1 - 0.017 14.7 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 PQQ-like domain Lycopene_cycl PF05834.12 KXG49182.1 - 0.071 12.2 0.1 0.14 11.2 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NaeI PF09126.10 KXG49182.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease NaeI NAD_binding_8 PF13450.6 KXG49182.1 - 0.26 11.5 2.3 6.9 7.0 0.0 3.0 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXG49182.1 - 1.7 8.6 3.6 14 5.6 0.1 3.0 3 1 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXG49182.1 - 3.6 6.3 6.2 1.8 7.3 0.2 2.4 3 0 0 3 3 3 0 Tryptophan halogenase GST_N PF02798.20 KXG49183.1 - 2e-14 53.7 0.0 3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXG49183.1 - 1.3e-13 50.9 0.0 2.2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXG49183.1 - 5e-10 39.3 0.0 1.2e-09 38.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXG49183.1 - 1.1e-09 38.6 0.0 1.9e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXG49183.1 - 1.2e-09 38.2 0.0 2.8e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXG49183.1 - 8.2e-06 26.0 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KXG49183.1 - 0.031 14.1 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KXG49183.1 - 0.097 13.4 0.0 0.18 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GMC_oxred_N PF00732.19 KXG49184.1 - 1.8e-47 162.1 0.4 2.7e-47 161.6 0.4 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG49184.1 - 1.7e-32 112.9 0.1 3.4e-31 108.7 0.0 2.5 2 0 0 2 2 2 1 GMC oxidoreductase Thi4 PF01946.17 KXG49184.1 - 8.6e-07 28.4 0.0 5.7e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KXG49184.1 - 9e-07 28.3 0.4 1.4e-06 27.6 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG49184.1 - 2.4e-06 27.0 0.0 1.6e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXG49184.1 - 7.4e-06 25.4 0.1 1.4e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXG49184.1 - 4e-05 23.7 0.8 0.00044 20.4 0.4 2.6 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXG49184.1 - 0.00014 21.5 0.5 0.016 14.8 0.2 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXG49184.1 - 0.0009 18.7 0.9 0.0015 17.9 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXG49184.1 - 0.0044 16.1 0.0 0.021 13.9 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KXG49184.1 - 0.0098 14.6 0.1 0.018 13.8 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein ThiF PF00899.21 KXG49184.1 - 0.027 13.8 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.12 KXG49184.1 - 0.083 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KXG49184.1 - 0.11 11.4 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 KXG49184.1 - 0.13 12.8 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BTB_2 PF02214.22 KXG49185.1 - 2.9e-09 37.1 0.2 2.9e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 KXG49185.1 - 0.041 14.1 0.0 4 7.7 0.0 2.6 2 0 0 2 2 2 0 BTB/POZ domain Methyltr_RsmB-F PF01189.17 KXG49186.1 - 1.1e-15 57.9 0.0 1e-09 38.4 0.0 2.5 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Acetyltransf_1 PF00583.25 KXG49187.1 - 4.6e-08 33.3 0.0 9.2e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXG49187.1 - 3.6e-05 23.7 0.0 0.28 11.1 0.0 2.4 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXG49187.1 - 0.00014 22.2 0.0 0.00033 21.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXG49187.1 - 0.0019 18.3 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FYVE PF01363.21 KXG49188.1 - 6.8e-15 55.0 7.7 1.1e-14 54.3 7.7 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 KXG49188.1 - 0.02 15.0 9.5 0.04 14.1 9.5 1.4 1 0 0 1 1 1 0 AN1-like Zinc finger 2-Hacid_dh_C PF02826.19 KXG49189.1 - 3.1e-52 176.5 0.0 4.7e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXG49189.1 - 6.7e-30 103.5 0.0 7.9e-30 103.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 KXG49189.1 - 0.011 15.1 0.3 0.45 9.8 0.3 2.2 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KXG49189.1 - 0.023 14.9 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glycos_transf_1 PF00534.20 KXG49190.1 - 1.2e-34 119.3 0.0 1.7e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXG49190.1 - 5.7e-29 101.3 0.0 9.8e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXG49190.1 - 3e-13 50.1 0.0 1.1e-12 48.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KXG49190.1 - 1.3e-09 38.7 0.0 3.1e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KXG49190.1 - 1.7e-08 34.7 0.0 4.3e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 GST_N PF02798.20 KXG49191.1 - 1.3e-12 47.9 0.2 2.8e-12 46.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXG49191.1 - 3.1e-09 37.1 0.0 6.2e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXG49191.1 - 9.4e-09 35.5 0.1 2.5e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXG49191.1 - 4.8e-07 29.7 0.0 1.1e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXG49191.1 - 2.5e-06 27.6 0.0 4.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXG49191.1 - 2.1e-05 24.7 0.0 3.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXG49191.1 - 0.0097 16.5 0.0 0.024 15.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain NDUF_B4 PF07225.12 KXG49192.1 - 2.6e-06 27.3 0.0 2.8e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) SAP18 PF06487.12 KXG49193.1 - 5.8e-47 159.4 0.0 7.1e-47 159.1 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.15 KXG49194.1 - 6.4e-55 185.1 0.1 6.4e-55 185.1 0.1 1.8 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KXG49194.1 - 2.7e-11 42.8 1.4 2.7e-11 42.8 1.4 3.0 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like TFIIA PF03153.13 KXG49194.1 - 1.6 8.6 7.4 2.8 7.8 7.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Polysacc_deac_1 PF01522.21 KXG49195.1 - 6.4e-18 64.8 0.0 1.1e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase HD PF01966.22 KXG49195.1 - 3.7e-06 27.1 0.0 7.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 HD domain Polysacc_deac_2 PF04748.13 KXG49195.1 - 0.0051 16.0 0.0 0.014 14.6 0.0 1.7 2 0 0 2 2 2 1 Divergent polysaccharide deacetylase Arf PF00025.21 KXG49197.1 - 1.3e-39 135.5 0.0 6.1e-26 90.9 0.0 2.3 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 KXG49197.1 - 2.3e-14 53.3 0.0 1.8e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KXG49197.1 - 2e-10 40.9 0.0 9.2e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXG49197.1 - 1.3e-06 28.4 0.0 2.5e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KXG49197.1 - 1.5e-06 27.9 0.0 0.0012 18.5 0.0 2.7 2 1 0 2 2 2 2 Ras family Gtr1_RagA PF04670.12 KXG49197.1 - 2.3e-06 27.2 0.0 3.3e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KXG49197.1 - 3.4e-06 26.6 0.0 2.9e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KXG49197.1 - 0.00024 20.7 0.1 0.015 14.9 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KXG49197.1 - 0.064 12.8 0.1 0.13 11.8 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 KXG49197.1 - 0.11 13.0 0.0 0.14 12.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter PIGA PF08288.12 KXG49198.1 - 1.5e-45 153.7 2.3 3.2e-45 152.6 1.1 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KXG49198.1 - 2.5e-27 95.9 0.3 3.8e-27 95.3 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KXG49198.1 - 8.2e-27 93.8 0.0 1.3e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXG49198.1 - 6.4e-24 84.9 0.1 1.5e-23 83.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXG49198.1 - 1.5e-11 45.0 0.0 2.5e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KXG49198.1 - 0.00064 19.8 0.1 0.0013 18.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KXG49198.1 - 0.004 17.5 0.0 0.018 15.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KXG49198.1 - 0.11 12.2 0.0 0.24 11.0 0.0 1.5 1 1 0 1 1 1 0 Starch synthase catalytic domain DEAD PF00270.29 KXG49199.1 - 2.8e-34 118.4 0.0 8.1e-16 58.3 0.0 2.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG49199.1 - 6.5e-20 71.5 0.1 1.9e-19 70.0 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG49199.1 - 5.9e-08 32.9 0.0 4.1e-07 30.2 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SDA1 PF05285.12 KXG49199.1 - 0.00093 18.7 19.4 0.00093 18.7 19.4 2.2 2 0 0 2 2 2 1 SDA1 AAA_22 PF13401.6 KXG49199.1 - 0.13 12.5 0.0 12 6.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain Abhydrolase_7 PF12715.7 KXG49199.1 - 0.19 10.9 0.0 7.8 5.6 0.0 2.2 2 0 0 2 2 2 0 Abhydrolase family Glyco_hydro_3_C PF01915.22 KXG49200.1 - 2.4e-47 161.5 0.0 4.1e-47 160.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXG49200.1 - 3.9e-33 115.2 0.0 1e-32 113.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXG49200.1 - 2.6e-08 33.8 0.0 6.9e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain DDR PF08841.10 KXG49200.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Ank_2 PF12796.7 KXG49201.1 - 7.3e-48 161.1 4.1 4.4e-11 43.2 0.0 4.9 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG49201.1 - 4.8e-36 122.7 4.4 5.6e-07 30.0 0.1 8.0 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG49201.1 - 3.5e-31 103.7 5.6 0.0025 18.2 0.0 10.4 10 0 0 10 10 10 7 Ankyrin repeat Ank PF00023.30 KXG49201.1 - 2.8e-29 100.3 20.3 7.6e-05 23.0 0.0 9.3 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KXG49201.1 - 1.8e-23 82.3 7.6 0.00013 22.1 0.0 6.7 2 2 4 7 7 7 7 Ankyrin repeats (many copies) NACHT PF05729.12 KXG49201.1 - 2.9e-06 27.3 0.0 5.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXG49201.1 - 0.00082 19.7 0.0 0.0022 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain CHAD PF05235.14 KXG49201.1 - 0.0012 18.8 0.2 1.6 8.6 0.1 2.6 2 1 0 2 2 2 2 CHAD domain AAA_16 PF13191.6 KXG49201.1 - 0.01 16.3 0.0 0.075 13.4 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.14 KXG49201.1 - 0.13 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain Fungal_trans PF04082.18 KXG49202.1 - 8.9e-16 57.7 0.2 1.5e-15 56.9 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TCTP PF00838.17 KXG49203.1 - 7.7e-52 176.0 0.4 8.7e-52 175.8 0.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein SPOUT_MTase PF02590.17 KXG49203.1 - 0.076 13.0 0.6 0.41 10.6 0.5 1.8 1 1 1 2 2 2 0 Predicted SPOUT methyltransferase Frigida PF07899.11 KXG49203.1 - 0.091 12.0 0.2 0.13 11.5 0.2 1.1 1 0 0 1 1 1 0 Frigida-like protein FA_hydroxylase PF04116.13 KXG49204.1 - 5.7e-24 85.0 13.6 5.7e-24 85.0 13.6 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SRP19 PF01922.17 KXG49207.1 - 1.5e-35 122.0 0.0 2.4e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Aminotran_3 PF00202.21 KXG49208.1 - 1.4e-92 310.4 0.0 2e-92 310.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III EGF_alliinase PF04863.13 KXG49208.1 - 0.045 14.2 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Alliinase EGF-like domain CPSF73-100_C PF11718.8 KXG49209.1 - 2e-83 279.2 0.0 2.8e-83 278.7 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KXG49209.1 - 1.3e-28 99.5 0.0 2.9e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 KXG49209.1 - 1.5e-18 67.5 2.3 1.8e-18 67.3 0.1 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KXG49209.1 - 2e-15 56.8 0.0 3.2e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KXG49209.1 - 1.3e-11 44.2 0.0 2.7e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KXG49209.1 - 0.0018 17.8 0.1 0.0043 16.6 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXG49209.1 - 0.0071 16.2 0.0 0.018 14.9 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain LegC3_N PF18654.1 KXG49209.1 - 0.014 14.6 0.3 0.022 14.0 0.3 1.2 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain TAF4 PF05236.14 KXG49210.1 - 1.6e-30 106.8 0.6 2.4e-23 83.3 1.4 2.2 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family DUF2075 PF09848.9 KXG49210.1 - 0.43 9.8 1.7 0.84 8.8 1.7 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pkinase PF00069.25 KXG49211.1 - 1.2e-49 169.0 0.0 2.8e-49 167.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG49211.1 - 7.5e-19 68.0 0.0 3.3e-18 65.9 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Amidase PF01425.21 KXG49212.1 - 1e-75 255.5 2.0 1.2e-74 251.9 2.0 2.0 1 1 0 1 1 1 1 Amidase Mtc PF03820.17 KXG49213.1 - 2.8e-119 397.8 0.1 3.1e-119 397.6 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF2293 PF10056.9 KXG49215.1 - 3.3e-28 97.7 0.1 1.3e-27 95.8 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) Gly_transf_sug PF04488.15 KXG49217.1 - 2.3e-13 50.6 0.1 1.5e-12 48.0 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TRI5 PF06330.11 KXG49219.1 - 3.9e-16 58.9 1.9 8.3e-15 54.5 0.2 2.0 1 1 1 2 2 2 2 Trichodiene synthase (TRI5) p450 PF00067.22 KXG49221.1 - 4.1e-70 236.8 0.0 5.1e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KXG49222.1 - 2.8e-14 53.1 2.6 1.8e-13 50.5 2.6 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXG49222.1 - 5.1e-07 29.6 2.8 1.2e-06 28.4 2.1 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXG49222.1 - 0.00051 20.5 0.9 0.0021 18.6 0.9 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG49222.1 - 0.00057 20.1 0.6 0.0014 18.8 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG49222.1 - 0.0022 17.3 0.2 0.0069 15.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXG49222.1 - 0.012 15.5 0.3 0.024 14.5 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KXG49222.1 - 0.038 13.1 0.5 0.06 12.4 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KXG49222.1 - 0.073 11.8 0.5 0.12 11.0 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 KXG49222.1 - 0.077 12.1 1.5 0.12 11.4 1.5 1.3 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 KXG49222.1 - 0.097 12.0 0.1 0.2 10.9 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RNR_inhib PF08591.10 KXG49223.1 - 3.5e-18 66.9 0.1 9.3e-18 65.5 0.1 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor SDA1 PF05285.12 KXG49224.1 - 6.2e-89 298.8 50.4 6.3e-89 298.8 43.7 2.8 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 KXG49224.1 - 8.9e-22 77.2 0.1 2.4e-21 75.8 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain Ribosomal_S7 PF00177.21 KXG49225.1 - 3.7e-36 124.0 1.1 4.7e-36 123.7 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e AMP-binding PF00501.28 KXG49226.1 - 2.4e-67 227.4 1.4 1.7e-37 129.0 0.0 4.5 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 KXG49226.1 - 2.6e-09 37.9 0.0 7.5e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 KXG49226.1 - 0.019 14.9 0.3 0.044 13.8 0.3 1.5 1 0 0 1 1 1 0 Gas vesicle protein G Sulfatase PF00884.23 KXG49227.1 - 1.7e-64 218.2 0.3 2.5e-64 217.6 0.3 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXG49227.1 - 0.0058 16.3 2.7 0.018 14.6 2.7 1.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HMGL-like PF00682.19 KXG49228.1 - 1.7e-80 270.4 0.0 2.5e-80 269.9 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KXG49228.1 - 1.6e-22 79.8 0.0 3.5e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain tRNA-synt_2b PF00587.25 KXG49229.1 - 1.9e-31 109.4 0.0 3e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXG49229.1 - 8.7e-07 29.0 0.2 1e-05 25.6 0.2 2.2 1 1 0 1 1 1 1 Anticodon binding domain Baculo_PEP_C PF04513.12 KXG49230.1 - 0.036 14.1 2.0 1.1 9.2 0.3 2.3 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_16 PF00722.21 KXG49231.1 - 6.4e-44 149.5 2.1 6.4e-44 149.5 2.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_hydro_31 PF01055.26 KXG49232.1 - 1.7e-162 541.6 0.4 2.1e-162 541.3 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KXG49232.1 - 3.1e-32 111.2 0.0 5.5e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KXG49232.1 - 9.5e-16 57.9 0.6 9.5e-16 57.9 0.6 2.6 4 0 0 4 4 4 1 Galactose mutarotase-like ADH_N PF08240.12 KXG49233.1 - 3.2e-27 94.6 2.4 3.2e-27 94.6 2.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG49233.1 - 3.5e-13 49.7 0.0 5.8e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXG49233.1 - 0.0001 21.9 0.3 0.37 10.2 0.1 3.2 3 0 0 3 3 3 2 Glucose dehydrogenase C-terminus S1-like PF14444.6 KXG49233.1 - 0.17 11.8 0.1 3 7.8 0.0 2.4 2 0 0 2 2 2 0 S1-like ATP-synt_G PF04718.15 KXG49234.1 - 2.4e-32 111.7 0.0 4.3e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit LEA_4 PF02987.16 KXG49234.1 - 0.16 12.1 0.5 0.27 11.4 0.5 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein DEAD PF00270.29 KXG49235.1 - 4e-27 95.1 0.0 1.3e-26 93.5 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG49235.1 - 5.4e-23 81.4 0.0 1.3e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG49235.1 - 5.3e-05 23.3 0.1 0.00014 21.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 KXG49235.1 - 0.024 13.5 0.0 0.05 12.4 0.0 1.5 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Pannexin_like PF12534.8 KXG49235.1 - 8.7 5.3 5.5 15 4.6 5.5 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Methyltransf_16 PF10294.9 KXG49237.1 - 6.8e-20 71.5 0.0 1.2e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KXG49237.1 - 0.00013 21.9 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG49237.1 - 0.0017 19.0 0.0 0.0037 17.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG49237.1 - 0.052 14.3 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXG49237.1 - 0.093 12.5 0.0 0.28 11.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KXG49237.1 - 0.22 11.1 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain VPS28 PF03997.12 KXG49238.1 - 4.5e-73 245.0 0.0 5.2e-73 244.8 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Noc2 PF03715.13 KXG49239.1 - 3.6e-128 427.0 0.2 8.1e-128 425.9 0.2 1.6 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 KXG49239.1 - 0.007 14.6 0.0 0.007 14.6 0.0 3.2 2 1 1 3 3 3 1 Nop14-like family TrkH PF02386.16 KXG49240.1 - 7.8e-94 314.9 7.0 6.3e-90 302.0 2.8 2.1 2 0 0 2 2 2 2 Cation transport protein MoaC PF01967.21 KXG49240.1 - 7.1e-46 155.7 0.4 1.3e-45 154.8 0.4 1.4 1 0 0 1 1 1 1 MoaC family ABC_tran PF00005.27 KXG49240.1 - 6.7e-43 146.5 9.3 3.5e-22 79.4 0.2 3.8 3 1 0 3 3 2 2 ABC transporter Mob_synth_C PF06463.13 KXG49240.1 - 2.9e-36 124.2 0.1 1.1e-35 122.3 0.0 2.1 2 0 0 2 2 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KXG49240.1 - 3e-26 92.8 0.0 6.5e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily AAA_21 PF13304.6 KXG49240.1 - 1.1e-12 48.3 9.2 0.00039 20.3 0.3 4.3 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 KXG49240.1 - 1.2e-07 31.6 6.0 1.2e-07 31.6 6.0 2.0 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 KXG49240.1 - 3.9e-07 29.8 4.4 0.12 11.8 0.0 4.4 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXG49240.1 - 1.6e-05 24.6 1.0 0.034 13.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXG49240.1 - 1.7e-05 24.9 1.0 0.27 11.3 0.2 3.3 3 0 0 3 3 2 2 50S ribosome-binding GTPase Fer4_12 PF13353.6 KXG49240.1 - 0.00012 22.3 0.0 0.00033 20.9 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain AAA_30 PF13604.6 KXG49240.1 - 0.00021 21.1 1.1 0.068 12.9 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXG49240.1 - 0.00027 21.3 1.2 0.56 10.6 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 KXG49240.1 - 0.00063 20.0 1.0 0.061 13.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXG49240.1 - 0.0026 17.7 0.4 1.6 8.6 0.1 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KXG49240.1 - 0.0044 17.6 0.1 3.8 8.1 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXG49240.1 - 0.0049 17.2 0.7 3.6 7.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXG49240.1 - 0.0065 16.6 0.3 7 6.8 0.1 2.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXG49240.1 - 0.0078 16.1 0.5 5.1 7.0 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_23 PF13476.6 KXG49240.1 - 0.0097 16.4 16.7 0.41 11.1 0.0 3.7 2 1 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KXG49240.1 - 0.017 14.7 0.7 0.11 12.1 0.2 2.5 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KXG49240.1 - 0.02 13.5 4.8 2.1 6.9 0.1 3.0 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 KXG49240.1 - 0.049 12.6 0.7 5.2 6.0 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KXG49240.1 - 0.11 12.9 2.0 5 7.6 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KXG49240.1 - 0.15 11.7 0.5 3.6 7.1 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KXG49240.1 - 0.17 12.0 7.4 2 8.5 0.1 3.8 4 0 0 4 4 4 0 Helicase HerA, central domain RNA_helicase PF00910.22 KXG49240.1 - 0.17 12.3 0.2 5 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MobB PF03205.14 KXG49240.1 - 0.51 10.2 3.1 1.4 8.8 0.2 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.6 KXG49240.1 - 1.1 8.9 5.0 6 6.5 0.1 3.0 3 1 0 3 3 3 0 AAA ATPase domain bZIP_1 PF00170.21 KXG49241.1 - 4e-07 30.0 11.0 7.9e-07 29.1 11.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXG49241.1 - 0.28 11.3 16.6 0.024 14.7 10.8 2.3 2 1 0 2 2 2 0 Basic region leucine zipper Lactamase_B_4 PF13691.6 KXG49242.1 - 2.7e-25 87.8 0.1 6.2e-25 86.7 0.1 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KXG49242.1 - 9.4e-12 44.9 0.0 2.7e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 Beta-lactamase superfamily domain DUF2188 PF09954.9 KXG49242.1 - 0.061 13.5 0.2 0.061 13.5 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Lactamase_B PF00753.27 KXG49242.1 - 0.073 13.1 0.0 0.34 10.9 0.0 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily His_Phos_2 PF00328.22 KXG49243.1 - 1.4e-11 44.4 0.0 1e-09 38.2 0.0 2.4 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) adh_short PF00106.25 KXG49244.1 - 1.3e-31 109.5 0.1 2.6e-31 108.6 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG49244.1 - 9.1e-17 61.4 0.1 1.9e-16 60.3 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG49244.1 - 1.4e-07 31.6 0.4 2.3e-06 27.6 0.4 2.1 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXG49244.1 - 0.047 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) cobW PF02492.19 KXG49245.1 - 3.1e-49 167.0 5.5 6e-37 126.9 0.7 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXG49245.1 - 1.7e-21 75.9 0.1 6.8e-17 61.2 0.0 2.8 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 KXG49245.1 - 0.0026 17.6 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 KXG49245.1 - 0.0064 16.9 0.3 0.027 14.9 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 KXG49245.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KXG49245.1 - 0.031 14.4 0.0 0.18 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KXG49245.1 - 0.052 13.3 0.1 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 KXG49245.1 - 0.056 12.5 0.6 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein MeaB PF03308.16 KXG49245.1 - 0.069 12.1 1.4 3 6.7 0.1 2.7 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 KXG49245.1 - 0.082 12.7 0.1 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KXG49245.1 - 0.084 13.2 0.3 0.3 11.4 0.3 2.1 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXG49245.1 - 0.091 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 KXG49245.1 - 0.19 12.2 0.6 1.2 9.6 0.6 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SelP_N PF04592.14 KXG49245.1 - 2.6 7.4 7.5 9.8 5.5 0.1 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Gtr1_RagA PF04670.12 KXG49246.1 - 1.1e-55 188.5 0.3 2.2e-55 187.5 0.1 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KXG49246.1 - 0.05 13.4 0.1 0.085 12.6 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Cyt-b5 PF00173.28 KXG49247.1 - 1.7e-11 44.1 0.0 2.4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NQR2_RnfD_RnfE PF03116.15 KXG49247.1 - 0.029 13.8 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family Ribosomal_S25 PF03297.15 KXG49248.1 - 4.6e-38 129.5 3.0 5e-38 129.4 3.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.12 KXG49248.1 - 0.033 13.9 0.1 0.044 13.5 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain MarR_2 PF12802.7 KXG49248.1 - 0.037 13.9 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 KXG49248.1 - 0.076 13.4 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_24 PF13412.6 KXG49248.1 - 0.089 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding APH PF01636.23 KXG49249.1 - 6.3e-09 36.1 0.0 1.3e-08 35.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Zip PF02535.22 KXG49249.1 - 0.12 11.6 0.1 0.16 11.2 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter p450 PF00067.22 KXG49253.1 - 8.9e-45 153.3 0.0 1.9e-44 152.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 GST_N_2 PF13409.6 KXG49253.1 - 0.00026 21.2 0.0 0.00079 19.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXG49253.1 - 0.0015 18.9 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXG49253.1 - 0.0047 16.9 0.0 0.016 15.2 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXG49253.1 - 0.059 13.6 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXG49253.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AA_permease_2 PF13520.6 KXG49254.1 - 2.4e-60 204.6 42.9 2.8e-60 204.3 42.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG49254.1 - 4.2e-26 91.6 33.0 5.6e-26 91.2 33.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2721 PF11026.8 KXG49255.1 - 0.31 10.9 12.7 0.21 11.5 1.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DUF998 PF06197.13 KXG49255.1 - 0.64 9.6 8.6 0.69 9.5 1.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF998) Gpr1_Fun34_YaaH PF01184.19 KXG49256.1 - 3.5e-31 108.4 21.7 4.2e-31 108.2 21.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family YfhO PF09586.10 KXG49256.1 - 0.29 9.3 6.4 0.42 8.8 6.4 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO ADH_N PF08240.12 KXG49257.1 - 1.4e-29 102.1 1.0 2.5e-29 101.3 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG49257.1 - 3.9e-23 81.8 0.1 6.3e-23 81.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG49257.1 - 0.00068 20.7 0.0 0.0011 20.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXG49257.1 - 0.0039 16.6 0.2 0.0071 15.7 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXG49257.1 - 0.02 14.2 0.6 0.031 13.6 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KXG49257.1 - 0.031 13.7 0.3 0.055 12.9 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Aldedh PF00171.22 KXG49258.1 - 1.9e-183 610.2 0.6 2.2e-183 610.0 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GST_N_3 PF13417.6 KXG49259.1 - 4.3e-16 59.1 0.0 7.7e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXG49259.1 - 9.8e-15 54.7 0.0 4.1e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXG49259.1 - 7.9e-14 51.7 0.0 1.9e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXG49259.1 - 2.4e-10 40.5 0.0 4.3e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXG49259.1 - 1.1e-07 31.9 0.0 2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXG49259.1 - 0.023 14.7 0.1 0.053 13.6 0.1 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Metallophos PF00149.28 KXG49260.1 - 4.9e-10 40.2 0.2 8.5e-10 39.5 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXG49260.1 - 5.3e-08 33.2 0.2 1.6e-06 28.5 0.2 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_S39 PF02122.15 KXG49260.1 - 0.041 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Peptidase S39 Dus PF01207.17 KXG49261.1 - 9e-59 199.1 0.0 1.3e-58 198.6 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KXG49261.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase PD40 PF07676.12 KXG49262.1 - 0.00022 21.1 0.8 0.21 11.6 0.2 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KXG49262.1 - 0.0003 21.0 0.2 22 5.4 0.0 4.4 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Proteasome_A_N PF10584.9 KXG49262.1 - 0.0029 17.2 0.5 0.21 11.3 0.0 3.4 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature WD40 PF00400.32 KXG49262.1 - 0.14 13.1 8.2 8.2 7.5 0.3 4.6 5 1 1 6 6 6 0 WD domain, G-beta repeat DIOX_N PF14226.6 KXG49263.1 - 2.9e-20 73.2 0.0 4.9e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG49263.1 - 2.7e-14 53.5 0.0 4.7e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1564 PF07600.11 KXG49264.1 - 0.013 15.2 0.0 0.037 13.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) DIOX_N PF14226.6 KXG49265.1 - 3.5e-24 85.8 0.0 6.4e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG49265.1 - 1.6e-10 41.3 0.0 3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Asp_Glu_race PF01177.22 KXG49266.1 - 5.6e-15 55.8 0.0 9e-15 55.1 0.0 1.4 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Pantoate_transf PF02548.15 KXG49266.1 - 0.0027 17.1 0.2 0.62 9.4 0.0 2.1 1 1 0 2 2 2 2 Ketopantoate hydroxymethyltransferase AroM PF07302.11 KXG49266.1 - 0.0036 16.7 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 2 AroM protein Lipoxygenase PF00305.19 KXG49267.1 - 2.2e-48 165.2 6.2 3.3e-46 158.0 5.1 2.2 2 1 0 2 2 2 2 Lipoxygenase Questin_oxidase PF14027.6 KXG49269.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Questin oxidase-like SKG6 PF08693.10 KXG49270.1 - 0.0004 19.7 0.1 0.00087 18.6 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain BatA PF07584.11 KXG49270.1 - 0.15 12.4 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Phage_HK97_TLTM PF06120.11 KXG49270.1 - 0.2 10.8 0.1 0.26 10.4 0.1 1.1 1 0 0 1 1 1 0 Tail length tape measure protein SSP160 PF06933.11 KXG49270.1 - 0.33 9.1 4.3 0.44 8.7 4.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Metallophos PF00149.28 KXG49271.1 - 2.3e-12 47.9 0.2 3.4e-12 47.3 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXG49271.1 - 6.8e-05 23.1 0.0 0.0096 16.1 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain DLH PF01738.18 KXG49272.1 - 9e-23 81.0 0.0 1.3e-10 41.2 0.0 3.0 3 0 0 3 3 3 3 Dienelactone hydrolase family Methyltransf_31 PF13847.6 KXG49273.1 - 4.8e-27 94.6 0.0 7.9e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG49273.1 - 7.4e-23 81.1 0.0 2.4e-22 79.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG49273.1 - 1e-22 80.6 0.0 1.8e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG49273.1 - 4.3e-16 59.2 0.0 6.2e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG49273.1 - 6e-16 58.5 0.0 2.1e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXG49273.1 - 3.1e-14 53.5 0.0 5.6e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KXG49273.1 - 7.3e-10 38.3 0.0 1e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 KXG49273.1 - 2.9e-07 30.3 0.0 4.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KXG49273.1 - 5.3e-07 29.3 0.0 7.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KXG49273.1 - 1.7e-05 24.3 0.0 2.2e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 KXG49273.1 - 5.5e-05 23.0 0.0 7.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 KXG49273.1 - 0.00027 20.8 0.0 0.0024 17.8 0.0 1.9 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 KXG49273.1 - 0.00059 19.4 0.0 0.00083 18.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.11 KXG49273.1 - 0.0048 16.5 0.0 0.0071 16.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltr_RsmB-F PF01189.17 KXG49273.1 - 0.0076 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_PK PF05891.12 KXG49273.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_32 PF13679.6 KXG49273.1 - 0.039 13.9 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KXG49273.1 - 0.06 12.4 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CMAS PF02353.20 KXG49273.1 - 0.081 12.2 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DREV PF05219.12 KXG49273.1 - 0.091 11.8 0.0 0.18 10.9 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase PrmA PF06325.13 KXG49273.1 - 0.097 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KXG49273.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 2 0 0 2 2 1 0 FtsJ-like methyltransferase Methyltransf_29 PF03141.16 KXG49273.1 - 0.11 11.0 0.2 0.28 9.7 0.2 1.8 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase GST_N_2 PF13409.6 KXG49274.1 - 2.2e-08 34.3 0.0 4.3e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXG49274.1 - 1.6e-07 31.6 0.0 3.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXG49274.1 - 3.1e-06 27.3 0.0 6.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXG49274.1 - 1.7e-05 25.1 0.0 3.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXG49274.1 - 3.2e-05 24.1 0.0 6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXG49274.1 - 0.00059 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ADH_zinc_N PF00107.26 KXG49275.1 - 1.6e-10 41.0 0.1 2.9e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG49275.1 - 0.00015 21.7 2.4 0.00022 21.1 0.2 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Peptidase_S15 PF02129.18 KXG49276.1 - 1.9e-11 44.1 0.0 3.3e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KXG49276.1 - 2.1e-10 40.3 0.0 7.1e-09 35.3 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXG49276.1 - 6.8e-09 35.5 0.0 3.1e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KXG49276.1 - 7.1e-08 32.6 0.0 2.1e-07 31.1 0.0 1.8 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 KXG49276.1 - 8.7e-08 32.0 0.0 3.7e-07 29.9 0.0 2.0 2 1 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 KXG49276.1 - 1.8e-06 26.9 0.1 0.00023 19.9 0.0 2.6 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KXG49276.1 - 2.5e-06 27.3 0.0 1e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1100 PF06500.11 KXG49276.1 - 6.7e-05 21.9 0.0 0.00011 21.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_3 PF07859.13 KXG49276.1 - 0.00017 21.5 0.0 0.00037 20.4 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold FAD_binding_3 PF01494.19 KXG49277.1 - 1.1e-26 93.9 0.0 2.8e-26 92.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG49277.1 - 5.7e-06 25.8 0.4 5.2e-05 22.6 0.4 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG49277.1 - 0.00011 22.7 1.0 0.31 11.6 0.1 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG49277.1 - 0.0027 17.4 0.5 0.023 14.3 0.0 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXG49277.1 - 0.035 13.4 0.1 2.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S9 PF00326.21 KXG49278.1 - 2.3e-07 30.5 0.0 0.012 15.1 0.0 2.2 1 1 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXG49278.1 - 7.2e-06 25.4 0.0 2.3e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 KXG49278.1 - 1.2e-05 24.2 0.0 0.0012 17.6 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) DLH PF01738.18 KXG49278.1 - 0.00094 18.8 0.0 0.029 13.9 0.0 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXG49278.1 - 0.0013 18.4 0.1 0.5 10.0 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 KXG49278.1 - 0.047 13.6 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal ketoacyl-synt PF00109.26 KXG49279.1 - 6.5e-73 245.4 0.0 2.3e-72 243.6 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXG49279.1 - 8.2e-50 169.2 0.0 1.7e-47 161.7 0.0 2.7 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KXG49279.1 - 3e-48 164.6 0.0 4.9e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXG49279.1 - 6.6e-45 154.0 0.0 1.2e-44 153.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KXG49279.1 - 2.7e-32 112.0 0.0 1.6e-30 106.1 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 KXG49279.1 - 3.1e-29 101.4 0.0 7.1e-29 100.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KXG49279.1 - 2.2e-17 63.6 0.0 5.9e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG49279.1 - 5.9e-14 52.5 0.0 1.9e-13 50.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXG49279.1 - 2.6e-13 50.4 0.0 5.7e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 KXG49279.1 - 2.5e-12 47.3 0.0 9.3e-12 45.4 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Epimerase PF01370.21 KXG49279.1 - 1.4e-10 41.0 0.0 2.8e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KXG49279.1 - 5.6e-10 39.0 0.0 1.7e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KXG49279.1 - 5.9e-10 39.2 0.0 1.3e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG49279.1 - 4.5e-09 36.3 0.0 1.2e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 KXG49279.1 - 2e-08 33.6 0.0 4.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 KXG49279.1 - 2.4e-08 33.8 0.0 7.7e-08 32.2 0.0 1.9 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KXG49279.1 - 4.9e-08 33.2 0.1 1.6e-07 31.6 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 KXG49279.1 - 2.7e-07 30.2 0.0 5.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXG49279.1 - 0.0016 18.0 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Thiolase_N PF00108.23 KXG49279.1 - 0.0078 15.6 0.1 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 KXG49279.1 - 0.03 14.1 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase GDP_Man_Dehyd PF16363.5 KXG49279.1 - 0.031 13.7 0.0 0.22 10.9 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase RrnaAD PF00398.20 KXG49279.1 - 0.12 11.4 0.1 0.41 9.7 0.0 1.8 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.6 KXG49279.1 - 0.15 13.1 0.0 0.67 11.0 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain PmbA_TldD PF01523.16 KXG49279.1 - 0.19 11.6 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Methyltransf_33 PF10017.9 KXG49279.1 - 0.2 10.8 0.0 0.44 9.7 0.0 1.5 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent MFS_1 PF07690.16 KXG49280.1 - 9.3e-38 130.0 47.4 3.9e-37 128.0 47.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.18 KXG49281.1 - 2.1e-06 27.8 9.4 5.9e-06 26.3 9.4 1.8 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXG49282.1 - 8.1e-24 84.1 1.3 1.3e-23 83.4 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMN_dh PF01070.18 KXG49283.1 - 1.1e-98 330.5 0.3 4.9e-98 328.4 0.3 1.9 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Sugar_tr PF00083.24 KXG49283.1 - 7.1e-92 308.6 25.9 9e-92 308.3 25.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG49283.1 - 7.3e-39 133.7 46.5 5.1e-33 114.5 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyt-b5 PF00173.28 KXG49283.1 - 7.3e-20 70.9 0.0 1.5e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXG49283.1 - 1.8e-05 24.0 0.1 3.1e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXG49283.1 - 0.00028 20.0 0.5 0.00088 18.4 0.1 1.9 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXG49283.1 - 0.14 11.5 0.4 0.22 10.8 0.4 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Mannosidase_ig PF17786.1 KXG49284.1 - 1.1e-14 54.8 0.1 2.5e-14 53.7 0.1 1.7 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KXG49284.1 - 6.7e-05 22.6 0.0 0.00022 20.9 0.0 1.9 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 KXG49284.1 - 0.00016 22.3 0.0 0.00067 20.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KXG49284.1 - 0.0007 18.8 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KXG49284.1 - 0.023 14.6 0.0 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain Fungal_lectin PF07938.12 KXG49285.1 - 6.7e-08 32.3 0.1 0.0031 17.0 0.0 2.7 1 1 1 2 2 2 2 Fungal fucose-specific lectin FlgD_ig PF13860.6 KXG49286.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 FlgD Ig-like domain Pec_lyase_C PF00544.19 KXG49287.1 - 1.1e-15 57.8 12.5 2.1e-14 53.6 11.6 2.7 2 1 0 2 2 2 1 Pectate lyase Beta_helix PF13229.6 KXG49287.1 - 9.6e-05 22.3 17.1 0.00057 19.8 2.1 2.6 1 1 0 2 2 2 2 Right handed beta helix region Ribosomal_L7Ae PF01248.26 KXG49288.1 - 1.3e-19 69.7 0.0 1.6e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KXG49288.1 - 0.00018 21.6 0.2 0.00019 21.5 0.2 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 MFS_1 PF07690.16 KXG49289.1 - 1.2e-48 165.9 36.3 1.9e-48 165.2 36.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG49289.1 - 2.9e-12 46.2 5.2 2.9e-12 46.2 5.2 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter Methyltransf_25 PF13649.6 KXG49289.1 - 9.7e-09 35.8 0.0 2.8e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG49289.1 - 4.2e-07 30.5 0.0 1.2e-06 29.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TRI12 PF06609.13 KXG49289.1 - 2.2e-05 23.1 3.9 4.1e-05 22.2 3.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_31 PF13847.6 KXG49289.1 - 3.1e-05 23.8 0.1 0.00021 21.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG49289.1 - 0.0012 19.5 0.1 0.0051 17.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG49289.1 - 0.0038 17.1 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXG49289.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.22 KXG49290.1 - 2.3e-69 234.4 0.0 3.1e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1759 PF03564.15 KXG49290.1 - 0.031 14.2 0.1 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Amino_oxidase PF01593.24 KXG49291.1 - 2.4e-12 46.9 0.0 3.2e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KXG49291.1 - 4.2e-08 33.0 0.2 6.3e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG49291.1 - 5.3e-08 33.0 0.1 1.5e-07 31.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXG49291.1 - 5.7e-05 23.6 0.6 0.0065 17.0 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXG49291.1 - 0.00011 21.1 0.0 0.00052 18.8 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KXG49291.1 - 0.00032 20.1 1.0 0.0082 15.4 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG49291.1 - 0.00033 20.0 0.0 0.0072 15.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG49291.1 - 0.00039 19.6 0.3 0.001 18.3 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXG49291.1 - 0.0024 17.5 0.7 0.016 14.8 0.1 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXG49291.1 - 0.01 15.1 0.0 0.053 12.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXG49291.1 - 0.025 14.2 0.2 0.043 13.5 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 KXG49291.1 - 0.053 12.8 0.1 0.091 12.0 0.1 1.2 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KXG49291.1 - 0.089 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.6 KXG49291.1 - 0.13 11.4 0.0 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_DMAT PF11991.8 KXG49292.1 - 4.7e-102 342.1 0.0 6.1e-102 341.7 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase ketoacyl-synt PF00109.26 KXG49293.1 - 1.3e-76 257.6 0.0 8.9e-75 251.5 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 KXG49293.1 - 6.8e-73 245.7 0.1 1.4e-72 244.7 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KXG49293.1 - 1e-57 195.8 0.0 1.6e-57 195.2 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.21 KXG49293.1 - 1.1e-51 176.2 0.0 3.1e-51 174.8 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXG49293.1 - 2.8e-48 164.7 0.0 4.1e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KXG49293.1 - 3.1e-29 101.4 0.1 1.1e-28 99.6 0.0 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 KXG49293.1 - 7.7e-25 87.8 0.0 1.9e-23 83.3 0.0 2.7 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 KXG49293.1 - 4.4e-22 78.5 0.0 1.1e-20 73.9 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KXG49293.1 - 1.3e-18 67.1 0.3 5.7e-09 36.2 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KXG49293.1 - 6.1e-14 52.6 0.0 1.7e-13 51.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG49293.1 - 6.5e-14 52.1 0.0 2.2e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG49293.1 - 1e-12 48.6 0.1 4.2e-12 46.6 0.1 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG49293.1 - 1.4e-11 44.9 0.0 4.3e-11 43.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXG49293.1 - 3e-11 43.7 0.0 8.1e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 KXG49293.1 - 6.7e-11 42.2 0.0 1.4e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KXG49293.1 - 4.4e-10 39.4 0.0 8.8e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.18 KXG49293.1 - 1.6e-07 30.9 0.0 3.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KXG49293.1 - 5e-07 29.6 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase AMP-binding_C PF13193.6 KXG49293.1 - 1.6e-05 25.8 0.0 5.9e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 KXG49293.1 - 1.6e-05 24.4 0.2 6.8e-05 22.4 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain RrnaAD PF00398.20 KXG49293.1 - 0.0019 17.3 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 KXG49293.1 - 0.0024 17.7 0.9 0.0038 17.0 0.0 1.7 2 0 0 2 2 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KXG49293.1 - 0.0028 17.2 0.0 0.0084 15.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain 3Beta_HSD PF01073.19 KXG49293.1 - 0.0064 15.5 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_28 PF02636.17 KXG49293.1 - 0.012 15.3 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Rsm22 PF09243.10 KXG49293.1 - 0.017 14.4 0.1 0.031 13.5 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 DREV PF05219.12 KXG49293.1 - 0.026 13.6 0.0 0.067 12.3 0.0 1.6 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_24 PF13578.6 KXG49293.1 - 0.052 14.6 0.2 0.31 12.1 0.1 2.5 2 0 0 2 2 1 0 Methyltransferase domain adh_short PF00106.25 KXG49293.1 - 0.069 12.6 0.5 1.5 8.2 0.0 2.8 3 0 0 3 3 3 0 short chain dehydrogenase ACP_syn_III PF08545.10 KXG49293.1 - 0.19 11.6 0.5 0.97 9.3 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AMP-binding PF00501.28 KXG49294.1 - 4.3e-134 447.3 0.0 3.8e-67 226.7 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KXG49294.1 - 1.3e-108 363.7 0.0 2.3e-35 122.1 0.0 4.6 4 1 0 4 4 4 4 Condensation domain PP-binding PF00550.25 KXG49294.1 - 4.2e-29 100.7 2.7 2.4e-12 47.0 0.1 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXG49294.1 - 9e-07 29.8 0.0 0.57 11.2 0.0 3.8 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain 2-oxoacid_dh PF00198.23 KXG49294.1 - 0.034 13.6 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) MFS_1 PF07690.16 KXG49295.1 - 3.3e-24 85.5 16.8 3.3e-24 85.5 16.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KXG49296.1 - 1.5e-47 162.3 30.6 1.5e-47 162.3 30.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG49296.1 - 2.8e-10 39.7 10.0 2.8e-10 39.7 10.0 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXG49296.1 - 4.7e-10 38.5 2.7 8.5e-10 37.7 2.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PUCC PF03209.15 KXG49296.1 - 0.0022 17.0 5.3 0.0022 17.0 5.3 2.1 3 0 0 3 3 3 1 PUCC protein TRAP-gamma PF07074.12 KXG49296.1 - 0.037 13.6 0.3 0.15 11.7 0.1 2.1 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Lyase_aromatic PF00221.19 KXG49297.1 - 2.8e-141 471.4 5.9 3.5e-141 471.0 5.9 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase EBP PF05241.12 KXG49298.1 - 8.9e-53 178.4 5.6 1.1e-52 178.0 5.6 1.1 1 0 0 1 1 1 1 Emopamil binding protein Sugar_tr PF00083.24 KXG49299.1 - 1.3e-110 370.4 27.9 1.6e-110 370.1 27.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG49299.1 - 2.4e-19 69.5 36.3 8.3e-13 48.0 13.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OppC_N PF12911.7 KXG49299.1 - 1 9.4 4.1 0.53 10.3 0.3 2.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C MJ1316 PF04457.12 KXG49300.1 - 1.4e-19 70.6 0.4 1.9e-19 70.2 0.4 1.2 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain MIF PF01187.18 KXG49301.1 - 9.6e-08 32.3 0.1 2e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Macro PF01661.21 KXG49302.1 - 5.5e-10 39.3 0.0 9.9e-09 35.3 0.0 2.2 1 1 0 1 1 1 1 Macro domain CENP-X PF09415.10 KXG49303.1 - 2.8e-28 98.0 0.5 6.4e-28 96.9 0.0 1.8 2 0 0 2 2 2 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 KXG49303.1 - 0.003 17.8 0.0 0.0059 16.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2934 PF11154.8 KXG49303.1 - 0.066 12.9 0.3 0.11 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) Striatin PF08232.12 KXG49303.1 - 0.8 10.3 7.4 0.21 12.2 4.4 1.6 2 0 0 2 2 2 0 Striatin family Presenilin PF01080.17 KXG49303.1 - 2.9 6.6 5.6 2.9 6.6 5.6 1.2 1 0 0 1 1 1 0 Presenilin Hamartin PF04388.12 KXG49303.1 - 5.3 5.6 14.9 6.4 5.3 14.9 1.0 1 0 0 1 1 1 0 Hamartin protein DUF5094 PF17015.5 KXG49303.1 - 8.9 6.4 6.8 6.4 6.8 5.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) Dicty_REP PF05086.12 KXG49303.1 - 9.7 4.0 8.1 11 3.8 8.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mis12 PF05859.12 KXG49305.1 - 2.8e-47 160.2 0.0 5.4e-47 159.2 0.0 1.5 1 0 0 1 1 1 1 Mis12 protein Amidohydro_1 PF01979.20 KXG49306.1 - 8e-05 22.1 0.0 0.00014 21.3 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 KXG49306.1 - 0.00014 21.7 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Sensor PF13796.6 KXG49307.1 - 0.044 13.8 0.1 0.044 13.8 0.1 2.8 2 1 0 2 2 2 0 Putative sensor CD20 PF04103.15 KXG49307.1 - 0.072 13.2 1.3 0.21 11.7 1.2 2.0 1 1 0 1 1 1 0 CD20-like family SK_channel PF03530.14 KXG49307.1 - 0.2 11.6 0.6 0.92 9.5 0.0 2.1 2 1 0 2 2 2 0 Calcium-activated SK potassium channel Syndecan PF01034.20 KXG49307.1 - 1 9.3 3.3 1.4 8.9 0.2 2.4 2 0 0 2 2 2 0 Syndecan domain BCNT PF07572.12 KXG49308.1 - 1.1e-24 86.3 1.1 3.2e-24 84.8 1.1 1.8 1 0 0 1 1 1 1 Bucentaur or craniofacial development TFIIF_alpha PF05793.12 KXG49308.1 - 0.0099 14.5 22.4 0.015 13.9 22.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribonuclease_T2 PF00445.18 KXG49309.1 - 5.6e-44 150.5 1.2 8.2e-44 150.0 1.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family GT-D PF08759.11 KXG49309.1 - 0.11 12.1 0.2 0.19 11.4 0.2 1.3 1 1 0 1 1 1 0 Glycosyltransferase GT-D fold MFS_1 PF07690.16 KXG49310.1 - 1.1e-35 123.2 43.1 6e-29 101.1 20.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXG49310.1 - 3.3e-05 22.4 1.3 3.3e-05 22.4 1.3 1.7 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family zf-C2H2 PF00096.26 KXG49311.1 - 1.9e-08 34.3 12.5 0.00028 21.1 3.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXG49311.1 - 0.00012 22.3 4.8 0.00012 22.3 4.8 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXG49311.1 - 0.00019 22.0 8.9 0.0054 17.5 3.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KXG49311.1 - 0.0011 19.5 4.8 0.42 11.3 0.5 2.4 1 1 1 2 2 2 2 FOXP coiled-coil domain Sina PF03145.16 KXG49311.1 - 0.062 13.2 1.9 0.093 12.7 1.9 1.2 1 0 0 1 1 1 0 Seven in absentia protein family Spt20 PF12090.8 KXG49312.1 - 1.1e-59 201.9 0.2 1.1e-59 201.9 0.2 6.1 3 1 0 4 4 4 1 Spt20 family Hexapep PF00132.24 KXG49314.1 - 4.5e-09 35.7 3.9 0.0017 18.0 1.0 3.7 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KXG49314.1 - 0.0003 19.8 0.4 0.00053 19.0 0.4 1.4 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 KXG49314.1 - 0.00083 17.6 1.2 0.0012 17.1 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KXG49314.1 - 0.21 11.4 5.1 12 5.8 1.6 3.2 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase MFS_1 PF07690.16 KXG49316.1 - 7.1e-35 120.6 29.8 1e-34 120.1 29.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PhoLip_ATPase_C PF16212.5 KXG49316.1 - 2.6 7.7 20.3 0.029 14.1 6.8 2.8 1 1 2 3 3 3 0 Phospholipid-translocating P-type ATPase C-terminal Glyco_hydro_35 PF01301.19 KXG49318.1 - 9.6e-81 271.8 0.4 9.6e-81 271.8 0.4 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KXG49318.1 - 1.4e-58 196.4 11.1 6.5e-35 120.2 0.3 3.3 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KXG49318.1 - 2.4e-57 193.7 1.9 2.4e-57 193.7 1.9 1.7 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KXG49318.1 - 2e-28 97.8 0.2 2e-28 97.8 0.2 2.3 3 0 0 3 3 3 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 KXG49318.1 - 6.9e-06 25.7 0.2 1.6e-05 24.5 0.2 1.6 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Amidohydro_2 PF04909.14 KXG49318.1 - 0.059 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase ELO PF01151.18 KXG49319.1 - 9.3e-84 280.8 7.3 1.1e-83 280.6 7.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family AIM3 PF17096.5 KXG49320.1 - 0.0063 17.4 0.1 0.0063 17.4 0.1 4.9 4 1 0 4 4 4 1 Altered inheritance of mitochondria protein 3 MT0933_antitox PF14013.6 KXG49320.1 - 1.2 9.5 8.4 60 4.1 1.7 4.0 2 1 2 4 4 4 0 MT0933-like antitoxin protein FAD_binding_4 PF01565.23 KXG49321.1 - 4.1e-19 68.7 0.1 7.8e-19 67.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG49321.1 - 0.0055 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Thioesterase PF00975.20 KXG49322.1 - 0.00027 21.1 1.2 0.0016 18.6 0.0 2.3 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 KXG49322.1 - 0.0016 19.1 0.0 0.0028 18.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KXG49322.1 - 0.0083 15.9 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KXG49322.1 - 0.0085 16.0 0.2 0.024 14.5 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.8 KXG49322.1 - 0.03 13.9 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 KXG49322.1 - 0.034 13.4 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KXG49322.1 - 0.07 13.0 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Macoilin PF09726.9 KXG49322.1 - 0.075 11.6 7.2 0.094 11.3 7.2 1.1 1 0 0 1 1 1 0 Macoilin family LIDHydrolase PF10230.9 KXG49322.1 - 0.097 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Na_H_Exchanger PF00999.21 KXG49323.1 - 3.2e-40 138.1 28.3 6.6e-40 137.1 28.3 1.5 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3506 PF12014.8 KXG49323.1 - 0.092 12.8 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) SKG6 PF08693.10 KXG49324.1 - 2.6e-05 23.5 2.8 0.00038 19.8 0.3 2.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KXG49324.1 - 6e-05 22.9 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 KXG49324.1 - 0.00075 19.4 2.5 0.0018 18.2 2.5 1.8 1 1 0 1 1 1 1 TMEM154 protein family RIFIN PF02009.16 KXG49324.1 - 0.089 12.7 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Rifin DUF3188 PF11384.8 KXG49324.1 - 0.12 12.1 1.0 0.27 11.0 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) MGC-24 PF05283.11 KXG49324.1 - 1.4 9.4 11.4 0.43 11.0 6.8 2.4 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SPX PF03105.19 KXG49324.1 - 1.5 8.6 7.5 2.1 8.2 7.5 1.3 1 0 0 1 1 1 0 SPX domain TruD PF01142.18 KXG49325.1 - 4e-64 217.0 4.5 8.5e-60 202.7 1.4 3.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Keratin_2_head PF16208.5 KXG49326.1 - 0.39 10.8 31.9 0.47 10.6 31.9 1.0 1 0 0 1 1 1 0 Keratin type II head HSP70 PF00012.20 KXG49327.1 - 5.3e-66 223.1 8.5 5.3e-66 223.1 8.5 2.5 2 1 0 2 2 2 1 Hsp70 protein Lebercilin PF15619.6 KXG49327.1 - 0.78 9.4 13.8 1.9 8.1 3.3 2.8 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease NACHT_N PF17100.5 KXG49327.1 - 9.6 6.0 8.7 0.43 10.4 0.7 2.4 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase Tubulin_3 PF14881.6 KXG49329.1 - 6.4e-85 283.4 0.1 1.2e-84 282.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KXG49329.1 - 4e-43 146.5 0.4 2.3e-42 144.0 0.1 2.4 3 0 0 3 3 3 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KXG49329.1 - 0.00076 19.7 0.0 0.55 10.4 0.0 2.6 2 1 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain TTKRSYEDQ PF10212.9 KXG49330.1 - 0.23 10.4 9.2 0.29 10.1 8.8 1.3 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein Phage_lysis PF03245.13 KXG49330.1 - 0.69 10.1 10.4 0.45 10.6 3.0 2.9 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein AATF-Che1 PF13339.6 KXG49330.1 - 0.87 10.3 9.0 4.9 7.8 9.0 2.3 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Spc7 PF08317.11 KXG49330.1 - 2.3 7.0 23.7 0.96 8.3 19.7 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2347 PF09804.9 KXG49331.1 - 1.7e-102 342.8 0.0 2.3e-102 342.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KXG49331.1 - 3.6e-60 203.6 0.1 5.3e-60 203.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.9 KXG49331.1 - 0.00058 18.7 0.0 1 8.0 0.0 2.6 2 1 1 3 3 3 2 Transport protein Avl9 SPA PF08616.10 KXG49331.1 - 0.0045 16.9 0.0 0.011 15.7 0.0 1.6 1 1 0 1 1 1 1 Stabilization of polarity axis Dyp_perox PF04261.12 KXG49332.1 - 2e-09 36.9 0.3 4.8e-07 29.1 0.0 3.2 4 0 0 4 4 4 2 Dyp-type peroxidase family PD40 PF07676.12 KXG49332.1 - 0.12 12.4 0.1 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF1929 PF09118.11 KXG49333.1 - 4.2e-22 78.3 0.0 8.3e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.25 KXG49333.1 - 3.4e-17 62.7 0.1 6.9e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 F5/8 type C domain Kelch_6 PF13964.6 KXG49333.1 - 1.1e-12 47.7 0.1 0.0002 21.6 0.0 3.8 2 1 1 3 3 3 2 Kelch motif Kelch_1 PF01344.25 KXG49333.1 - 3.9e-12 45.6 0.3 1.4e-06 27.7 0.0 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 KXG49333.1 - 1.8e-09 37.4 0.1 0.00069 19.6 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain NACHT PF05729.12 KXG49333.1 - 7.4e-08 32.5 0.0 3.2e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 NACHT domain Ank_2 PF12796.7 KXG49333.1 - 1.1e-07 32.4 1.6 0.72 10.5 0.2 5.8 5 2 2 7 7 5 3 Ankyrin repeats (3 copies) Glyoxal_oxid_N PF07250.11 KXG49333.1 - 8.6e-07 28.4 0.1 0.0016 17.7 0.1 2.5 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus NACHT_N PF17100.5 KXG49333.1 - 6e-05 23.0 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Kelch_2 PF07646.15 KXG49333.1 - 0.00021 21.1 0.0 0.55 10.3 0.0 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 KXG49333.1 - 0.00053 20.2 0.3 3.2 8.1 0.0 4.4 4 0 0 4 4 3 1 Galactose oxidase, central domain AAA_22 PF13401.6 KXG49333.1 - 0.00071 19.9 0.0 0.0022 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXG49333.1 - 0.017 15.5 0.0 0.056 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.14 KXG49333.1 - 0.02 14.1 0.1 0.057 12.7 0.1 1.7 2 0 0 2 2 2 0 KAP family P-loop domain Ank_5 PF13857.6 KXG49333.1 - 0.05 14.0 0.1 14 6.2 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeats (many copies) YhdB PF14148.6 KXG49333.1 - 0.11 12.6 0.0 7.2 6.8 0.0 2.7 2 0 0 2 2 2 0 YhdB-like protein SNF2_N PF00176.23 KXG49335.1 - 7.4e-55 186.1 0.0 1.1e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AA_permease_2 PF13520.6 KXG49335.1 - 7.1e-43 147.0 50.1 1e-42 146.5 50.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG49335.1 - 4.1e-15 55.4 41.5 6.4e-15 54.7 41.5 1.2 1 0 0 1 1 1 1 Amino acid permease Helicase_C PF00271.31 KXG49335.1 - 7.6e-15 55.2 0.0 1.4e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG49335.1 - 1.9e-09 37.7 0.0 3.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXG49335.1 - 0.002 17.9 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KXG49335.1 - 0.063 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KXG49335.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase EMC3_TMCO1 PF01956.16 KXG49336.1 - 0.049 13.4 5.0 1.5 8.5 0.1 2.5 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF2721 PF11026.8 KXG49336.1 - 0.16 11.8 7.1 3.3 7.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) AAA_2 PF07724.14 KXG49337.1 - 9.5e-47 159.3 0.0 1.9e-45 155.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KXG49337.1 - 3e-33 113.8 1.3 3e-33 113.8 1.3 3.2 3 0 0 3 3 3 1 AAA lid domain AAA PF00004.29 KXG49337.1 - 8.8e-27 94.1 0.3 1.4e-14 54.6 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KXG49337.1 - 6.3e-23 80.6 0.3 2.1e-22 79.0 0.3 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KXG49337.1 - 5.4e-15 55.6 0.0 4.2e-09 36.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXG49337.1 - 1.2e-13 51.5 0.0 6.6e-05 23.2 0.0 4.8 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 KXG49337.1 - 3.7e-12 46.9 7.3 9.3e-07 29.4 0.0 5.1 5 1 1 6 6 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KXG49337.1 - 1.1e-08 34.9 0.0 5.1e-05 23.0 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 KXG49337.1 - 1.7e-06 27.9 0.0 0.1 12.3 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.6 KXG49337.1 - 2e-06 27.9 0.0 0.05 13.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXG49337.1 - 2.4e-06 28.1 0.0 0.064 13.8 0.0 3.6 3 0 0 3 3 2 2 AAA domain TniB PF05621.11 KXG49337.1 - 2.9e-06 26.8 0.2 0.067 12.6 0.0 4.7 4 1 0 4 4 4 1 Bacterial TniB protein AAA_7 PF12775.7 KXG49337.1 - 3.4e-06 26.7 0.0 0.015 14.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 KXG49337.1 - 1.3e-05 24.7 0.0 0.2 11.0 0.0 3.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXG49337.1 - 1.7e-05 25.0 0.0 0.26 11.4 0.0 3.4 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KXG49337.1 - 6.8e-05 23.2 0.0 0.56 10.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 KXG49337.1 - 0.00011 22.5 1.3 0.61 10.3 0.0 3.4 3 1 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 KXG49337.1 - 0.00011 22.2 4.4 0.11 12.3 0.3 4.2 4 1 0 4 4 3 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KXG49337.1 - 0.00016 22.2 0.5 0.55 10.7 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_30 PF13604.6 KXG49337.1 - 0.00017 21.4 0.0 1.3 8.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.12 KXG49337.1 - 0.00033 20.4 1.5 3.1 7.5 0.9 4.3 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KXG49337.1 - 0.00034 20.5 0.0 1 9.2 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KXG49337.1 - 0.00039 20.4 0.0 0.33 11.0 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KXG49337.1 - 0.00058 19.8 0.0 0.59 10.0 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 KXG49337.1 - 0.00082 19.1 0.0 0.71 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXG49337.1 - 0.0013 18.4 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.6 KXG49337.1 - 0.0022 18.3 0.1 0.63 10.4 0.1 3.2 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 KXG49337.1 - 0.0028 16.8 0.1 0.026 13.6 0.0 2.5 2 1 0 2 2 2 1 Type II/IV secretion system protein Roc PF08477.13 KXG49337.1 - 0.0035 17.5 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KXG49337.1 - 0.0048 16.5 0.1 0.9 9.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXG49337.1 - 0.0077 16.2 0.0 0.5 10.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.15 KXG49337.1 - 0.011 15.7 0.0 0.3 11.0 0.0 2.9 3 0 0 3 3 3 0 NTPase SRP54 PF00448.22 KXG49337.1 - 0.023 14.3 0.1 7.9 6.1 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 KXG49337.1 - 0.029 14.9 11.2 0.52 10.8 0.0 4.2 4 1 0 4 4 4 0 AAA domain Clp_N PF02861.20 KXG49337.1 - 0.032 14.4 0.5 2.5 8.3 0.0 3.7 3 0 0 3 3 3 0 Clp amino terminal domain, pathogenicity island component ResIII PF04851.15 KXG49337.1 - 0.074 13.0 0.0 12 5.8 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Torsin PF06309.11 KXG49337.1 - 0.08 13.0 0.0 0.42 10.7 0.0 2.1 3 0 0 3 3 2 0 Torsin Rad17 PF03215.15 KXG49337.1 - 0.087 12.7 0.0 14 5.6 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain V_ATPase_I PF01496.19 KXG49337.1 - 0.49 8.2 3.2 0.72 7.7 3.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sulfotransfer_3 PF13469.6 KXG49338.1 - 0.019 15.4 0.9 1.4 9.3 0.0 3.0 3 1 0 3 3 3 0 Sulfotransferase family PD40 PF07676.12 KXG49339.1 - 9.2e-48 159.3 26.5 4.8e-09 35.9 0.5 9.6 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 KXG49339.1 - 2.3e-10 39.8 4.7 0.19 10.5 0.0 6.7 5 1 2 7 7 7 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF5050 PF16472.5 KXG49339.1 - 1.5e-07 30.9 0.7 0.0014 17.9 0.0 4.1 4 1 0 4 4 4 2 Domain of unknown function (DUF5050) DUF3748 PF12566.8 KXG49339.1 - 0.00017 21.5 0.6 13 5.8 0.0 4.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3748) WD40 PF00400.32 KXG49339.1 - 0.006 17.4 11.3 16 6.6 0.3 6.5 7 1 0 7 7 7 1 WD domain, G-beta repeat Proteasome_A_N PF10584.9 KXG49339.1 - 0.12 12.1 8.0 17 5.2 0.1 5.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature ATG27 PF09451.10 KXG49340.1 - 7.7e-88 294.8 0.0 9e-88 294.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KXG49340.1 - 4.8e-07 30.0 0.2 0.0014 18.7 0.1 3.0 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat Prefoldin_2 PF01920.20 KXG49341.1 - 3.3e-24 84.9 3.8 3.3e-24 84.9 3.8 1.5 2 0 0 2 2 2 1 Prefoldin subunit Rab5-bind PF09311.11 KXG49341.1 - 0.012 15.0 8.5 0.024 14.1 6.4 1.9 2 0 0 2 2 2 0 Rabaptin-like protein DUF4735 PF15882.5 KXG49341.1 - 0.015 14.7 0.3 0.021 14.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) DUF5065 PF16723.5 KXG49341.1 - 0.15 12.2 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) AKNA PF12443.8 KXG49341.1 - 0.17 12.5 0.1 0.17 12.5 0.1 2.2 1 1 1 2 2 2 0 AT-hook-containing transcription factor eIF-4B PF06273.11 KXG49341.1 - 0.21 10.6 4.9 0.25 10.4 4.9 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DivIC PF04977.15 KXG49341.1 - 0.7 9.7 9.2 7.3 6.4 5.1 2.3 2 0 0 2 2 2 0 Septum formation initiator NYAP_N PF15439.6 KXG49341.1 - 2.4 7.3 10.3 0.45 9.7 6.5 1.6 2 1 0 2 2 2 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter V_ATPase_I PF01496.19 KXG49341.1 - 4.7 5.0 5.6 9.5 4.0 5.2 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family HSP70 PF00012.20 KXG49342.1 - 3.5e-11 42.0 0.4 7e-10 37.7 0.2 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KXG49342.1 - 0.027 13.3 0.2 0.3 9.9 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein N2227 PF07942.12 KXG49343.1 - 6.5e-91 304.3 0.0 8.1e-91 304.0 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 KXG49343.1 - 0.0024 18.6 0.0 0.019 15.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG49343.1 - 0.0056 16.5 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG49343.1 - 0.0079 16.8 0.0 0.021 15.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG49343.1 - 0.2 11.5 0.0 0.98 9.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain PAC4 PF16093.5 KXG49344.1 - 3.2e-26 91.3 0.1 4.6e-26 90.8 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Fungal_trans PF04082.18 KXG49345.1 - 2.1e-21 76.1 0.0 4.8e-21 75.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG49345.1 - 1.5e-05 25.0 14.8 3.6e-05 23.8 14.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tmemb_cc2 PF10267.9 KXG49345.1 - 0.74 8.9 6.5 0.038 13.1 0.7 1.6 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Isochorismatase PF00857.20 KXG49346.1 - 8.7e-16 58.6 0.6 2.9e-15 56.9 0.6 1.7 1 1 0 1 1 1 1 Isochorismatase family 4HBT_3 PF13622.6 KXG49347.1 - 4.4e-78 263.0 0.1 5.2e-78 262.7 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KXG49347.1 - 3.2e-23 82.0 0.0 2.9e-12 46.6 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase DUF4277 PF14104.6 KXG49347.1 - 0.045 14.1 0.0 0.087 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4277) DUF3445 PF11927.8 KXG49348.1 - 2.6e-68 230.0 0.0 3e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF1917 PF08939.10 KXG49348.1 - 0.16 11.9 0.2 0.71 9.7 0.1 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF1917) MFS_1 PF07690.16 KXG49349.1 - 1.6e-36 126.0 34.7 1.6e-36 126.0 34.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG49349.1 - 8.2e-16 57.9 7.9 8.2e-16 57.9 7.9 2.3 2 2 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KXG49349.1 - 6.4e-06 24.9 1.4 6.4e-06 24.9 1.4 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Colicin_im PF03857.13 KXG49349.1 - 0.057 13.4 3.3 4 7.4 0.0 2.5 2 0 0 2 2 2 0 Colicin immunity protein DUF3632 PF12311.8 KXG49350.1 - 6.8e-38 130.8 1.4 8.4e-38 130.5 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Mito_carr PF00153.27 KXG49351.1 - 6.4e-45 151.0 7.5 1.1e-16 60.5 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pro_racemase PF05544.11 KXG49352.1 - 6.2e-58 196.4 0.0 8.7e-57 192.6 0.0 2.0 1 1 0 1 1 1 1 Proline racemase DUF4338 PF14236.6 KXG49352.1 - 0.073 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) PAP_central PF04928.17 KXG49353.1 - 1.1e-109 365.2 0.0 1.6e-109 364.7 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KXG49353.1 - 3.3e-60 202.6 0.0 5.1e-60 202.0 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KXG49353.1 - 2.1e-11 44.0 0.0 4.5e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KXG49353.1 - 0.13 12.0 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Abhydrolase_1 PF00561.20 KXG49354.1 - 8.1e-13 48.6 0.1 3.5e-12 46.5 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG49354.1 - 0.00044 20.9 0.0 0.00064 20.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG49354.1 - 0.0012 18.1 0.0 0.0025 17.1 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KXG49354.1 - 0.016 14.9 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Flavin_Reduct PF01613.18 KXG49355.1 - 5.7e-18 65.4 0.0 7.9e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 KXG49355.1 - 0.17 11.7 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Fungal_trans PF04082.18 KXG49356.1 - 6.8e-21 74.5 0.1 1.6e-19 70.0 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG49356.1 - 5.1e-06 26.5 4.3 9.6e-06 25.6 4.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 KXG49358.1 - 1.5e-23 82.4 0.1 1.9e-23 82.1 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXG49358.1 - 0.00082 19.4 0.0 0.0013 18.8 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif TLP1_add_C PF18313.1 KXG49358.1 - 0.049 13.6 0.4 0.092 12.7 0.4 1.4 1 1 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain PAP_PilO PF06864.12 KXG49358.1 - 0.11 11.3 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF4078 PF13300.6 KXG49358.1 - 0.18 12.2 0.2 0.22 11.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) Thioredoxin PF00085.20 KXG49359.1 - 7.5e-28 96.5 0.1 8.3e-28 96.4 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXG49359.1 - 2.3e-06 27.9 0.0 3.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KXG49359.1 - 2.4e-06 28.0 0.8 1.3e-05 25.6 0.8 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KXG49359.1 - 2.3e-05 23.9 0.0 2.7e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KXG49359.1 - 3.6e-05 23.7 0.0 4.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.16 KXG49359.1 - 0.0011 18.0 0.0 0.0013 17.7 0.0 1.0 1 0 0 1 1 1 1 Phosducin TraF PF13728.6 KXG49359.1 - 0.003 17.4 0.0 0.0035 17.2 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KXG49359.1 - 0.017 15.3 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 KXG49359.1 - 0.018 15.3 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin HR_lesion PF05514.11 KXG49359.1 - 0.018 15.2 0.0 0.018 15.2 0.0 1.1 1 0 0 1 1 1 0 HR-like lesion-inducing Redoxin PF08534.10 KXG49359.1 - 0.021 14.6 0.2 0.45 10.2 0.2 2.0 1 1 1 2 2 2 0 Redoxin CSN7a_helixI PF18392.1 KXG49359.1 - 0.067 13.1 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Thioredoxin_9 PF14595.6 KXG49359.1 - 0.097 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.6 KXG49359.1 - 0.16 12.2 0.5 13 5.9 0.2 2.0 1 1 1 2 2 2 0 Thioredoxin Cu-oxidase_3 PF07732.15 KXG49360.1 - 1.7e-31 108.7 2.3 4.6e-31 107.3 0.2 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXG49360.1 - 5.7e-31 107.1 4.1 1.9e-25 89.2 0.4 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KXG49360.1 - 4.1e-15 56.2 0.0 4.8e-14 52.8 0.0 2.5 2 1 0 2 2 2 1 Multicopper oxidase Homeobox_KN PF05920.11 KXG49361.1 - 2.8e-17 62.3 1.4 8.1e-17 60.8 1.4 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KXG49361.1 - 1.5e-07 31.1 0.1 3.4e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 Homeodomain zf-C2H2 PF00096.26 KXG49361.1 - 2.1e-05 24.7 13.7 0.056 13.9 1.3 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXG49361.1 - 0.00076 20.1 20.7 0.0008 20.1 1.2 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger HTH_Tnp_Tc5 PF03221.16 KXG49361.1 - 0.0094 16.0 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-C2H2_3rep PF18868.1 KXG49361.1 - 0.47 11.1 5.6 3.7 8.3 0.2 2.5 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 KXG49361.1 - 1.4 9.5 11.7 5.7 7.5 1.0 4.4 4 1 0 4 4 4 0 Zinc-finger double domain MFS_1 PF07690.16 KXG49362.1 - 7.6e-10 38.2 32.4 3.7e-08 32.7 14.2 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG49362.1 - 9.9e-06 24.7 9.2 9.9e-06 24.7 9.2 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KXG49362.1 - 3.5e-05 22.8 17.4 0.012 14.5 11.9 2.5 2 1 0 2 2 2 2 MFS_1 like family DUF1768 PF08719.11 KXG49363.1 - 3e-50 170.6 0.2 4.4e-50 170.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Asp_Glu_race PF01177.22 KXG49364.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.7 1 1 0 1 1 1 0 Asp/Glu/Hydantoin racemase SDH_sah PF01972.16 KXG49364.1 - 0.15 11.0 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Asp_Glu_race PF01177.22 KXG49366.1 - 5e-39 134.5 0.4 5.4e-39 134.3 0.4 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase TRAPPC10 PF12584.8 KXG49367.1 - 1.1e-45 155.2 0.0 2.2e-45 154.1 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 KXG49367.1 - 0.037 13.6 0.4 0.071 12.7 0.4 1.4 1 0 0 1 1 1 0 Foie gras liver health family 1 MBOAT_2 PF13813.6 KXG49368.1 - 1.9e-24 85.7 0.1 1.9e-24 85.7 0.1 1.9 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Aminotran_3 PF00202.21 KXG49369.1 - 6.2e-51 173.3 0.0 7.1e-50 169.8 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III TIG PF01833.24 KXG49370.1 - 3e-10 40.0 0.5 1e-09 38.4 0.3 2.0 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.6 KXG49370.1 - 2.7e-08 33.9 4.4 2.1e-05 24.7 0.9 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXG49370.1 - 9.6e-07 29.0 2.8 0.019 15.4 0.8 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KXG49370.1 - 3e-06 27.7 0.0 6.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG49370.1 - 4.9e-05 23.8 0.7 0.00029 21.3 0.3 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG49370.1 - 0.00046 20.4 0.4 2.2 9.1 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeat Birna_VP3 PF01767.16 KXG49370.1 - 0.17 12.0 2.3 0.86 9.7 1.0 2.3 2 0 0 2 2 2 0 Birnavirus VP3 protein Glyco_hydro_61 PF03443.14 KXG49371.1 - 6.3e-65 219.0 0.0 9.9e-65 218.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Serglycin PF04360.12 KXG49371.1 - 7.8e-05 22.7 3.3 0.00014 21.9 3.3 1.4 1 0 0 1 1 1 1 Serglycin SUI1 PF01253.22 KXG49373.1 - 1.8e-21 76.5 0.9 6.8e-21 74.6 0.9 2.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 KXG49373.1 - 9.9e-10 39.0 0.1 1.2e-08 35.5 0.1 2.7 1 1 0 1 1 1 1 Pre-PUA-like domain Kin17_mid PF10357.9 KXG49373.1 - 0.0045 16.9 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein Blt1 PF12754.7 KXG49373.1 - 0.091 13.1 2.4 11 6.4 0.4 2.7 2 0 0 2 2 2 0 Blt1 N-terminal domain Sulfatase PF00884.23 KXG49374.1 - 6.9e-21 74.9 1.0 1.2e-20 74.2 1.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXG49374.1 - 0.00045 19.9 0.1 0.00086 19.0 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KXG49374.1 - 0.017 13.7 0.0 0.024 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Dabb PF07876.12 KXG49375.1 - 6.3e-18 65.2 0.0 7e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain La PF05383.17 KXG49376.1 - 1.5e-21 76.2 0.0 2.5e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KXG49376.1 - 8.9e-09 35.0 0.0 2.5e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chitin_synth_2 PF03142.15 KXG49377.1 - 1.1e-25 90.2 2.5 6.3e-24 84.5 2.3 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXG49377.1 - 2.1e-15 57.1 3.9 2.1e-15 57.1 3.9 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXG49377.1 - 2.3e-08 34.2 0.0 6.9e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXG49377.1 - 0.094 12.5 0.1 10 5.9 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 HSP70 PF00012.20 KXG49378.1 - 4.6e-163 543.6 1.8 4.6e-163 543.6 1.8 1.8 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KXG49378.1 - 1.5e-10 40.4 0.0 1.3e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KXG49378.1 - 0.0062 16.9 0.4 6.3 7.3 0.0 3.0 2 2 0 2 2 2 2 Cell division protein FtsA BcrAD_BadFG PF01869.20 KXG49378.1 - 0.067 12.7 0.2 0.33 10.4 0.1 2.2 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Ketoacyl-synt_C PF02801.22 KXG49378.1 - 0.088 12.8 0.0 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain WLM PF08325.10 KXG49379.1 - 3.1e-52 177.4 0.0 7.9e-52 176.1 0.0 1.6 1 1 0 2 2 2 1 WLM domain DUF45 PF01863.17 KXG49379.1 - 0.0032 17.5 0.0 0.0086 16.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 KXG49379.1 - 0.0044 16.9 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 SprT-like family ubiquitin PF00240.23 KXG49379.1 - 0.088 12.6 0.0 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin family Thiolase_N PF00108.23 KXG49380.1 - 1.2e-69 234.6 0.1 1.8e-69 234.0 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXG49380.1 - 8e-41 138.5 0.4 8e-41 138.5 0.4 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXG49380.1 - 0.012 15.2 3.2 0.016 14.8 1.9 1.8 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Pkinase PF00069.25 KXG49381.1 - 1.9e-53 181.5 0.0 2.4e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG49381.1 - 9.7e-23 80.8 0.0 1.4e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG49381.1 - 0.00013 21.4 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXG49381.1 - 0.0009 18.3 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXG49381.1 - 0.0074 15.7 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXG49381.1 - 0.032 13.8 0.0 0.078 12.6 0.0 1.6 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KXG49381.1 - 0.042 13.8 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KXG49381.1 - 0.05 13.2 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Response_reg PF00072.24 KXG49381.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Response regulator receiver domain DASH_Ask1 PF08655.10 KXG49383.1 - 3.9e-30 103.5 0.4 8.1e-30 102.5 0.3 1.6 2 0 0 2 2 2 1 DASH complex subunit Ask1 HIG_1_N PF04588.13 KXG49384.1 - 2.4e-07 30.9 1.3 2.4e-07 30.9 1.3 1.6 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF3899 PF13038.6 KXG49384.1 - 2.8 8.5 5.3 48 4.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Med26 PF08711.11 KXG49385.1 - 2.2e-12 46.8 0.3 4.5e-12 45.8 0.3 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Nup54 PF13874.6 KXG49386.1 - 1.9e-41 141.5 2.0 5.3e-41 140.0 0.0 2.1 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 KXG49386.1 - 1.7e-12 46.7 4.2 3.1e-12 45.9 4.2 1.5 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Nucleoporin_FG PF13634.6 KXG49386.1 - 4.9e-08 33.7 70.5 3.7e-06 27.7 17.2 3.2 2 1 1 3 3 3 2 Nucleoporin FG repeat region Fib_alpha PF08702.10 KXG49386.1 - 5e-05 23.5 2.5 9.3e-05 22.6 2.5 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF948 PF06103.11 KXG49386.1 - 0.047 14.0 0.2 1.3 9.3 0.1 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) EzrA PF06160.12 KXG49386.1 - 0.06 11.5 6.9 0.033 12.4 3.9 1.7 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA V-SNARE_C PF12352.8 KXG49386.1 - 0.083 13.2 1.5 10 6.5 0.1 2.5 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Adhesin_P1_N PF18652.1 KXG49386.1 - 0.094 12.7 3.5 0.31 11.1 3.5 1.9 1 1 0 1 1 1 0 Adhesin P1 N-terminal domain DUF745 PF05335.13 KXG49386.1 - 0.14 11.8 8.7 0.041 13.6 5.6 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF745) Spc24 PF08286.11 KXG49386.1 - 0.28 11.5 4.4 0.79 10.0 0.9 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF2564 PF10819.8 KXG49386.1 - 0.31 11.5 5.1 0.15 12.5 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) Spc7 PF08317.11 KXG49386.1 - 0.83 8.5 9.7 0.99 8.2 9.0 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 KXG49386.1 - 1 8.7 10.0 1.4 8.2 8.5 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4164 PF13747.6 KXG49386.1 - 1.1 9.5 4.7 1.6 9.1 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Prefoldin PF02996.17 KXG49386.1 - 2 8.3 7.7 1.7 8.6 0.4 2.7 1 1 0 2 2 2 0 Prefoldin subunit CdvA PF18822.1 KXG49386.1 - 2.6 7.9 10.8 19 5.1 8.1 3.2 2 1 0 2 2 2 0 CdvA-like coiled-coil domain Tup_N PF08581.10 KXG49386.1 - 3.3 8.1 7.3 0.7 10.2 1.8 2.5 3 0 0 3 3 3 0 Tup N-terminal Cor1 PF04803.12 KXG49386.1 - 5.7 7.2 9.8 0.11 12.8 2.2 2.1 2 0 0 2 2 1 0 Cor1/Xlr/Xmr conserved region CHCH PF06747.13 KXG49387.1 - 9.7e-07 28.8 4.8 9.7e-07 28.8 4.8 2.6 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 KXG49387.1 - 0.0022 18.0 9.0 0.0036 17.3 3.1 2.3 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 KXG49387.1 - 0.12 12.7 10.3 14 6.1 0.3 3.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KXG49387.1 - 2.3 8.3 13.4 2.6 8.1 3.9 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 KXG49387.1 - 3.3 8.0 10.9 6.3 7.1 1.0 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Glyco_hydro_71 PF03659.14 KXG49388.1 - 2.8e-134 447.7 1.5 2.8e-134 447.7 1.5 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 AA_permease_2 PF13520.6 KXG49389.1 - 9e-61 206.0 51.3 1.4e-60 205.3 51.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG49389.1 - 3.4e-35 121.6 47.2 5.1e-35 121.0 47.2 1.1 1 0 0 1 1 1 1 Amino acid permease ACBP PF00887.19 KXG49389.1 - 2.8e-20 72.3 0.0 6.2e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein TMEM208_SND2 PF05620.11 KXG49389.1 - 0.47 10.2 4.6 12 5.6 0.1 3.0 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF5090 PF17009.5 KXG49389.1 - 2 8.4 5.0 5.1 7.0 5.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) JmjC PF02373.22 KXG49390.1 - 3e-38 130.8 2.0 3.9e-38 130.4 0.7 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KXG49390.1 - 1.8e-17 63.5 3.5 3.1e-17 62.7 3.5 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KXG49390.1 - 3.5e-17 62.4 3.4 7.1e-17 61.4 3.4 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.17 KXG49390.1 - 8.3e-16 57.7 0.6 2.2e-15 56.3 0.6 1.8 1 0 0 1 1 1 1 jmjN domain 4HBT_2 PF13279.6 KXG49391.1 - 1.2e-06 29.0 0.0 2.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acetyltransf_1 PF00583.25 KXG49392.1 - 0.00067 19.9 0.1 0.0011 19.2 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 KXG49392.1 - 0.01 16.0 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 KXG49392.1 - 0.03 14.7 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXG49392.1 - 0.15 12.0 0.0 0.44 10.5 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ERG4_ERG24 PF01222.17 KXG49393.1 - 1.9e-138 461.8 21.2 2.2e-138 461.6 21.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Sugar_tr PF00083.24 KXG49395.1 - 1.1e-77 261.8 13.0 1.3e-77 261.6 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG49395.1 - 0.0012 17.9 15.9 0.0012 17.9 15.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_5 PF05631.14 KXG49395.1 - 0.0058 15.6 0.6 0.0095 14.9 0.6 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM SH3_9 PF14604.6 KXG49396.1 - 8.7e-08 31.9 0.1 2.6e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXG49396.1 - 2e-06 27.3 0.0 3.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXG49396.1 - 2.2e-05 24.1 0.0 0.00016 21.3 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Podoplanin PF05808.11 KXG49396.1 - 3.2e-05 24.1 15.4 3.2e-05 24.1 15.4 1.8 2 0 0 2 2 2 1 Podoplanin LapA_dom PF06305.11 KXG49396.1 - 0.088 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain RIFIN PF02009.16 KXG49396.1 - 0.11 12.4 5.2 0.24 11.2 5.2 1.5 1 1 0 1 1 1 0 Rifin Presenilin PF01080.17 KXG49396.1 - 0.39 9.4 2.4 0.59 8.9 2.4 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KXG49396.1 - 0.4 10.5 11.1 0.62 9.8 11.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 KXG49396.1 - 1.7 7.4 8.7 2.9 6.6 8.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Plasmodium_Vir PF05795.11 KXG49396.1 - 4 6.8 6.1 6.9 6.0 6.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pkinase PF00069.25 KXG49397.1 - 9.2e-45 153.0 0.0 1.2e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG49397.1 - 8.5e-17 61.3 0.0 1.3e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXG49397.1 - 4.1e-05 23.6 0.8 0.21 11.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXG49397.1 - 0.00011 21.1 0.0 0.00029 19.7 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXG49397.1 - 0.00041 19.8 0.0 0.0007 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXG49397.1 - 0.0013 18.2 0.1 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family KIX_2 PF16987.5 KXG49397.1 - 0.0021 18.0 0.6 0.0035 17.3 0.6 1.3 1 0 0 1 1 1 1 KIX domain YrbL-PhoP_reg PF10707.9 KXG49397.1 - 0.033 13.7 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 KXG49397.1 - 0.084 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 muHD PF10291.9 KXG49398.1 - 3.9e-82 275.6 0.0 5.3e-82 275.2 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KXG49398.1 - 2.8e-07 30.7 0.0 1e-06 28.9 0.0 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain COG2 PF06148.11 KXG49398.1 - 0.038 14.1 2.0 0.045 13.8 0.6 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1202 PF06717.11 KXG49398.1 - 0.07 12.5 0.3 0.13 11.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) AMP-binding PF00501.28 KXG49399.1 - 5.4e-98 328.4 0.0 7.9e-98 327.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KXG49399.1 - 3.9e-85 285.5 0.6 8.6e-85 284.3 0.2 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXG49399.1 - 9.2e-64 214.7 0.1 2.5e-62 210.0 0.1 2.4 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 KXG49399.1 - 2.4e-47 161.3 0.0 1.2e-46 159.0 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein Acyl_transf_1 PF00698.21 KXG49399.1 - 1.8e-46 159.1 0.0 3.4e-46 158.2 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXG49399.1 - 1.2e-41 141.4 0.5 2.7e-41 140.3 0.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KXG49399.1 - 2.9e-38 131.8 0.1 5.1e-38 131.0 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KXG49399.1 - 1.4e-25 89.4 0.5 3.6e-11 43.2 0.0 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KXG49399.1 - 1.8e-14 54.1 0.0 4.1e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 KXG49399.1 - 8.4e-09 35.2 0.0 1.1e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 KXG49399.1 - 5.8e-08 33.3 0.0 3.5e-07 30.9 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG49399.1 - 9.3e-08 32.7 0.0 2.4e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXG49399.1 - 6e-07 29.1 0.0 1.9e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_11 PF08241.12 KXG49399.1 - 6.4e-06 26.7 0.0 3e-05 24.6 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KXG49399.1 - 4.2e-05 23.1 0.1 7.4e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 KXG49399.1 - 0.00016 21.2 0.0 0.043 13.2 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Methyltransf_23 PF13489.6 KXG49399.1 - 0.0042 16.9 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KXG49399.1 - 0.0045 16.6 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Nodulation protein S (NodS) Polysacc_synt_2 PF02719.15 KXG49399.1 - 0.016 14.4 0.0 3.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.13 KXG49399.1 - 0.11 12.0 0.1 11 5.5 0.0 2.5 2 0 0 2 2 2 0 NmrA-like family Pkinase PF00069.25 KXG49401.1 - 3.3e-17 62.7 0.0 2.3e-16 60.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG49401.1 - 1.1e-05 24.8 0.1 0.00025 20.4 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 KXG49402.1 - 1.8e-108 355.3 26.3 1e-12 48.5 0.1 15.2 4 3 10 16 16 16 15 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG49402.1 - 3.6e-83 273.0 24.7 1.1e-08 35.4 0.0 22.7 10 6 15 26 26 26 20 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG49402.1 - 7.4e-69 219.5 42.1 0.018 15.5 0.0 31.0 33 0 0 33 33 33 16 Ankyrin repeat Ank_5 PF13857.6 KXG49402.1 - 1.6e-57 190.8 33.1 7.1e-05 23.0 0.0 20.5 11 4 9 20 20 20 15 Ankyrin repeats (many copies) Ank PF00023.30 KXG49402.1 - 4.5e-45 150.2 65.2 0.012 16.0 0.0 30.2 32 0 0 32 32 32 12 Ankyrin repeat NACHT PF05729.12 KXG49402.1 - 3.2e-06 27.2 0.0 2.9e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Goodbye PF17109.5 KXG49402.1 - 9.4e-06 26.1 0.0 3.4e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain AAA_22 PF13401.6 KXG49402.1 - 6.5e-05 23.2 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXG49402.1 - 0.0019 18.6 0.0 0.016 15.6 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain CRAL_TRIO PF00650.20 KXG49403.1 - 6e-42 143.1 0.0 1.1e-41 142.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXG49403.1 - 2.1e-10 40.7 0.0 5.3e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXG49403.1 - 5.9e-05 23.2 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Fungal_trans PF04082.18 KXG49404.1 - 6.7e-08 31.9 0.6 4e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain ATPgrasp_N PF18130.1 KXG49405.1 - 1.6e-08 35.0 0.0 3.2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp N-terminal domain MFS_1 PF07690.16 KXG49406.1 - 1.3e-27 96.7 42.5 1.4e-25 90.0 23.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG49406.1 - 0.00065 18.2 6.0 0.00065 18.2 6.0 2.3 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Chromo PF00385.24 KXG49407.1 - 8.7e-10 38.4 0.1 1.8e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-bind_6 PF13921.6 KXG49407.1 - 0.038 14.2 0.2 0.092 13.0 0.2 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Mtf2_C PF14061.6 KXG49407.1 - 0.085 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 SANT_DAMP1_like PF16282.5 KXG49407.1 - 0.15 12.3 0.0 0.42 10.8 0.0 1.7 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 KXG49407.1 - 0.17 12.1 0.1 0.44 10.8 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain FtsJ PF01728.19 KXG49408.1 - 4.4e-14 53.0 0.0 6.2e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DDE_1 PF03184.19 KXG49409.1 - 1.3e-30 106.4 0.0 2.2e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KXG49409.1 - 1.1e-09 38.2 0.1 5.7e-09 35.9 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 KXG49409.1 - 7.7e-05 22.4 0.6 0.00019 21.1 0.0 1.9 2 0 0 2 2 2 1 helix-turn-helix, Psq domain Trimer_CC PF08954.11 KXG49410.1 - 0.24 11.0 3.9 1.3 8.6 1.0 2.4 2 0 0 2 2 2 0 Trimerisation motif Glyco_transf_20 PF00982.21 KXG49411.1 - 2.7e-150 501.2 0.0 4.3e-150 500.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KXG49411.1 - 4e-83 278.1 0.0 6.8e-83 277.4 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase MFS_1 PF07690.16 KXG49412.1 - 2.7e-17 62.7 50.1 2.7e-17 62.7 50.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PP28 PF10252.9 KXG49413.1 - 2.4e-29 101.6 15.8 2.4e-29 101.6 15.8 3.0 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 YL1 PF05764.13 KXG49413.1 - 0.046 13.8 34.1 0.061 13.4 34.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein AF-4 PF05110.13 KXG49413.1 - 6.4 4.7 30.3 7.3 4.5 30.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein UNC-50 PF05216.13 KXG49414.1 - 1.1e-86 289.9 8.1 1.3e-86 289.7 8.1 1.0 1 0 0 1 1 1 1 UNC-50 family Sec7 PF01369.20 KXG49415.1 - 2.7e-27 95.7 0.0 6.8e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KXG49415.1 - 9.7e-20 71.1 0.2 1e-18 67.8 0.0 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain Tektin PF03148.14 KXG49415.1 - 0.18 10.5 0.2 0.3 9.8 0.2 1.2 1 0 0 1 1 1 0 Tektin family Cnn_1N PF07989.11 KXG49416.1 - 5e-23 81.0 9.7 5e-23 81.0 9.7 11.9 7 1 3 11 11 11 2 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 KXG49416.1 - 3.3e-22 78.5 29.0 8.7e-18 64.4 16.8 12.2 12 3 3 15 15 15 2 Micro-tubular organiser Mto1 C-term Mto2-binding region ZnuA PF01297.17 KXG49416.1 - 0.065 12.6 8.8 0.056 12.8 6.1 2.4 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic QRPTase_C PF01729.19 KXG49417.1 - 4.6e-48 163.2 0.3 2e-46 157.8 0.3 2.0 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KXG49417.1 - 9.8e-23 80.0 0.0 3e-22 78.5 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.19 KXG49417.1 - 0.18 11.2 0.1 1.3 8.3 0.0 2.2 1 1 2 3 3 3 0 Ribulose-phosphate 3 epimerase family Aldose_epim PF01263.20 KXG49418.1 - 1e-60 205.6 0.0 1.1e-60 205.5 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Zn_clus PF00172.18 KXG49419.1 - 9.9e-09 35.2 13.2 1.6e-08 34.5 13.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YccV-like PF08755.11 KXG49420.1 - 1.4e-28 99.2 0.0 2.9e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 KXG49420.1 - 1.1e-10 41.3 0.0 2.1e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 KXG49420.1 - 3.2e-08 33.3 0.8 6.4e-08 32.4 0.8 1.5 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.11 KXG49420.1 - 0.00092 19.7 0.0 0.0016 19.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 KXG49420.1 - 0.046 13.6 0.3 0.046 13.6 0.3 1.8 2 0 0 2 2 2 0 F-box domain DnaJ PF00226.31 KXG49421.1 - 2.1e-24 85.4 0.3 6e-24 83.9 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 KXG49421.1 - 5.8e-10 39.2 11.2 2.5e-09 37.2 7.2 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXG49421.1 - 3.4e-07 30.4 5.3 3.4e-07 30.4 5.3 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXG49421.1 - 2.7e-06 27.6 5.6 0.0084 16.4 3.0 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KXG49421.1 - 3.1e-06 27.3 8.4 0.016 15.6 0.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXG49421.1 - 1.8e-05 25.2 6.2 0.13 13.2 2.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger DUF4303 PF14136.6 KXG49421.1 - 0.0077 16.0 0.8 0.025 14.3 0.8 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4303) zf-MYST PF17772.1 KXG49421.1 - 0.0097 15.5 0.1 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 MYST family zinc finger domain DUF2256 PF10013.9 KXG49421.1 - 0.011 15.9 0.3 7.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) MIEAP PF16026.5 KXG49421.1 - 0.047 13.9 4.7 0.16 12.1 4.7 2.0 1 1 0 1 1 1 0 Mitochondria-eating protein LIM PF00412.22 KXG49421.1 - 0.12 12.6 4.1 5.5 7.3 0.1 2.5 2 0 0 2 2 2 0 LIM domain zf-C2HE PF16278.5 KXG49421.1 - 0.42 11.1 4.5 4.7 7.7 0.5 3.9 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 KXG49421.1 - 0.78 9.4 4.0 21 4.8 0.1 2.7 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Cytochrome_C7 PF14522.6 KXG49421.1 - 1.4 9.0 5.3 1.8 8.6 1.3 2.6 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c UPF0449 PF15136.6 KXG49421.1 - 6 7.4 8.7 1.6 9.3 1.9 2.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 R3H PF01424.22 KXG49422.1 - 1e-11 44.6 0.0 2.8e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KXG49422.1 - 5.2e-10 39.1 0.3 1e-09 38.1 0.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXG49422.1 - 0.00029 20.9 0.3 0.0007 19.6 0.3 1.7 1 0 0 1 1 1 1 G-patch domain DUF4136 PF13590.6 KXG49422.1 - 0.062 13.9 0.1 0.24 12.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4136) Peptidase_C54 PF03416.19 KXG49423.1 - 1.6e-52 178.6 0.0 3.1e-45 154.8 0.0 2.1 1 1 1 2 2 2 2 Peptidase family C54 Histone PF00125.24 KXG49424.1 - 3.6e-21 75.9 0.3 4.4e-21 75.6 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXG49424.1 - 0.00029 21.1 1.1 0.0004 20.6 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXG49424.1 - 0.0005 20.5 0.0 0.00083 19.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KXG49424.1 - 0.036 13.7 0.1 0.082 12.5 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 KXG49425.1 - 4.5e-21 74.3 2.6 8e-21 73.5 2.6 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXG49425.1 - 6.6e-17 62.1 0.0 8.9e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXG49425.1 - 9.5e-06 25.8 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.15 KXG49426.1 - 3e-10 40.0 0.9 4e-10 39.6 0.9 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Phageshock_PspD PF09584.10 KXG49426.1 - 0.084 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Phage shock protein PspD (Phageshock_PspD) 2-oxoacid_dh PF00198.23 KXG49427.1 - 2.1e-79 266.2 0.0 2.8e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXG49427.1 - 5e-17 61.5 1.3 1e-16 60.5 1.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KXG49427.1 - 0.005 16.6 0.2 0.083 12.7 0.1 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KXG49427.1 - 0.012 16.3 0.2 0.47 11.2 0.1 2.4 1 1 0 1 1 1 0 HlyD family secretion protein Ribosomal_60s PF00428.19 KXG49427.1 - 0.016 15.8 1.2 0.016 15.8 1.2 2.7 1 1 1 2 2 2 0 60s Acidic ribosomal protein RnfC_N PF13375.6 KXG49427.1 - 0.039 13.9 0.3 0.35 10.9 0.3 2.3 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain PCMT PF01135.19 KXG49429.1 - 4.3e-65 219.4 0.0 5.1e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KXG49429.1 - 8.6e-09 35.4 0.0 1.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG49429.1 - 4.2e-07 30.6 0.0 8.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXG49429.1 - 7.9e-07 29.2 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG49429.1 - 0.00011 22.0 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG49429.1 - 0.00015 22.3 0.0 0.00027 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KXG49429.1 - 0.0037 16.9 0.0 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KXG49429.1 - 0.0094 15.5 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KXG49429.1 - 0.014 16.1 0.0 0.025 15.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 KXG49429.1 - 0.029 15.4 0.0 0.052 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KXG49429.1 - 0.034 13.5 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 KXG49429.1 - 0.034 14.1 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KXG49429.1 - 0.035 13.5 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GCD14 PF08704.10 KXG49429.1 - 0.089 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 KXG49429.1 - 0.11 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase RrnaAD PF00398.20 KXG49429.1 - 0.12 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CMAS PF02353.20 KXG49429.1 - 0.17 11.1 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DnaJ PF00226.31 KXG49430.1 - 2.8e-21 75.4 1.5 2.8e-21 75.4 1.5 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 KXG49430.1 - 3.5e-17 61.0 0.3 0.17 12.1 0.0 9.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXG49430.1 - 1.9e-15 55.9 0.0 0.00089 19.0 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXG49430.1 - 5.9e-11 42.7 5.3 0.00017 22.0 0.5 4.9 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXG49430.1 - 9.4e-11 41.6 11.2 0.066 14.1 0.1 7.8 4 3 4 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXG49430.1 - 1.3e-10 40.6 0.0 0.48 10.8 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXG49430.1 - 2e-10 40.7 8.3 0.00073 19.6 0.4 5.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXG49430.1 - 2.3e-08 34.1 6.9 0.99 10.2 0.0 8.6 8 1 2 10 10 9 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXG49430.1 - 3.8e-05 23.8 0.8 0.24 11.8 0.0 5.6 7 1 1 8 8 5 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KXG49430.1 - 4.2e-05 23.2 1.5 0.061 13.0 0.0 2.8 2 0 0 2 2 2 2 Bacterial type III secretion protein (HrpB1_HrpK) PknG_TPR PF16918.5 KXG49430.1 - 0.00016 20.5 0.2 0.015 14.1 0.0 2.8 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_11 PF13414.6 KXG49430.1 - 0.0062 16.2 0.0 1 9.1 0.0 4.2 4 1 1 5 5 4 1 TPR repeat Na_Ca_ex_C PF16494.5 KXG49430.1 - 0.009 16.5 0.2 0.009 16.5 0.2 2.5 3 0 0 3 3 2 1 C-terminal extension of sodium/calcium exchanger domain ANAPC3 PF12895.7 KXG49430.1 - 0.0094 16.2 10.3 0.29 11.4 1.4 4.9 3 2 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 YfiO PF13525.6 KXG49430.1 - 0.018 14.7 2.3 0.12 12.0 0.3 2.9 2 2 0 2 2 2 0 Outer membrane lipoprotein RPT PF13446.6 KXG49430.1 - 0.024 14.5 0.0 0.44 10.5 0.0 3.1 3 1 0 3 3 3 0 A repeated domain in UCH-protein TPR_7 PF13176.6 KXG49430.1 - 0.07 13.2 9.2 59 4.0 0.2 6.4 6 2 1 7 7 6 0 Tetratricopeptide repeat TPR_18 PF13512.6 KXG49430.1 - 0.075 13.1 1.2 0.36 10.9 0.9 2.5 2 1 0 2 2 1 0 Tetratricopeptide repeat DUF2786 PF10979.8 KXG49430.1 - 0.1 12.6 1.7 0.32 10.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2786) KORA PF16509.5 KXG49430.1 - 0.14 12.5 0.1 0.47 10.8 0.1 2.0 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor TPR_16 PF13432.6 KXG49430.1 - 0.89 10.3 21.5 5.6 7.7 0.0 7.0 7 2 1 8 8 8 0 Tetratricopeptide repeat PCRF PF03462.18 KXG49431.1 - 2.4e-48 164.6 0.0 2.5e-47 161.3 0.0 2.3 3 0 0 3 3 3 1 PCRF domain RF-1 PF00472.20 KXG49431.1 - 1.1e-33 115.6 1.1 2.4e-33 114.5 1.1 1.5 1 0 0 1 1 1 1 RF-1 domain Phage_tail_T PF06223.12 KXG49431.1 - 0.1 13.1 0.1 0.39 11.3 0.0 1.9 2 0 0 2 2 2 0 Minor tail protein T FYRC PF05965.14 KXG49431.1 - 0.11 12.6 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 F/Y rich C-terminus Mito_carr PF00153.27 KXG49432.1 - 1.9e-50 168.7 5.2 8.1e-21 73.8 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DEAD PF00270.29 KXG49433.1 - 1.1e-42 145.8 0.0 1.5e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG49433.1 - 5.8e-28 97.4 0.7 7.9e-27 93.8 0.5 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG49433.1 - 0.0074 16.3 0.0 0.018 15.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SMC_N PF02463.19 KXG49434.1 - 2.1e-24 86.2 0.0 4.6e-24 85.1 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXG49434.1 - 1.6e-18 67.9 5.9 1.6e-18 67.9 5.9 5.5 2 2 1 3 3 1 1 AAA domain AAA_15 PF13175.6 KXG49434.1 - 5.2e-10 39.6 13.4 5.2e-10 39.6 13.4 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KXG49434.1 - 1.4e-08 34.9 1.8 1.6e-05 24.9 0.2 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXG49434.1 - 0.00015 21.4 0.0 0.00033 20.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain CALCOCO1 PF07888.11 KXG49434.1 - 0.00056 18.9 30.7 0.00056 18.9 30.7 2.9 2 1 1 3 3 3 1 Calcium binding and coiled-coil domain (CALCOCO1) like TPR_MLP1_2 PF07926.12 KXG49434.1 - 0.011 15.8 19.1 0.011 15.8 19.1 6.2 3 2 3 6 6 5 0 TPR/MLP1/MLP2-like protein SMC_hinge PF06470.13 KXG49434.1 - 0.015 15.6 0.0 0.079 13.3 0.0 2.3 2 0 0 2 2 1 0 SMC proteins Flexible Hinge Domain SbcCD_C PF13558.6 KXG49434.1 - 0.019 15.2 0.1 0.12 12.7 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 KXG49434.1 - 0.093 13.2 0.2 0.093 13.2 0.2 5.4 3 2 0 3 3 3 0 ABC transporter Vac_Fusion PF02346.16 KXG49434.1 - 0.15 11.7 1.6 0.67 9.6 0.3 2.8 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 PAP_assoc PF03828.19 KXG49435.1 - 0.00062 19.9 0.0 0.0033 17.6 0.0 2.3 2 1 0 2 2 2 1 Cid1 family poly A polymerase ADIP PF11559.8 KXG49436.1 - 0.013 15.5 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding JIP_LZII PF16471.5 KXG49436.1 - 0.029 14.6 1.2 4.7 7.5 0.1 2.4 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Rnk_N PF14760.6 KXG49436.1 - 0.064 13.7 0.4 0.89 10.1 0.4 2.4 2 0 0 2 2 2 0 Rnk N-terminus Spc7 PF08317.11 KXG49436.1 - 0.067 12.1 0.9 0.11 11.3 0.9 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 KXG49437.1 - 0.0023 18.4 2.0 0.0032 18.0 2.0 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region ADIP PF11559.8 KXG49437.1 - 0.82 9.7 9.6 0.068 13.2 3.9 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DDE_3 PF13358.6 KXG49438.1 - 1.7e-31 109.0 0.0 1e-30 106.4 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_33 PF13592.6 KXG49438.1 - 5.8e-06 25.9 0.4 1.5e-05 24.6 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn helix DDE_1 PF03184.19 KXG49438.1 - 7.5e-05 22.4 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 KXG49438.1 - 0.00014 21.6 0.1 0.00051 19.7 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain rve PF00665.26 KXG49438.1 - 0.00015 22.0 0.0 0.00039 20.6 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain MarR PF01047.22 KXG49438.1 - 0.035 14.0 0.1 0.25 11.3 0.1 2.1 2 0 0 2 2 2 0 MarR family HTH_31 PF13560.6 KXG49438.1 - 0.069 13.5 0.0 1.3 9.4 0.0 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_32 PF13565.6 KXG49438.1 - 0.087 13.5 0.0 0.36 11.5 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_26 PF13443.6 KXG49438.1 - 0.1 13.1 0.1 3.8 8.0 0.1 2.6 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain GCP_C_terminal PF04130.13 KXG49438.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal HTH_IclR PF09339.10 KXG49438.1 - 0.14 12.0 0.2 0.8 9.5 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_AraC PF00165.23 KXG49438.1 - 1.3 9.2 4.6 13 6.0 0.1 3.5 4 0 0 4 4 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family HNH_2 PF13391.6 KXG49439.1 - 7.3e-16 58.1 0.0 1.3e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease DNA_pol_A_exo1 PF01612.20 KXG49440.1 - 1e-12 48.1 0.0 1.8e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease DNA_pol_B_2 PF03175.13 KXG49440.1 - 0.08 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Alpha-amylase PF00128.24 KXG49441.1 - 3.3e-55 188.0 0.6 1.3e-53 182.7 0.6 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KXG49441.1 - 0.0019 18.4 0.0 0.0049 17.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Ank_2 PF12796.7 KXG49442.1 - 3.5e-45 152.5 0.0 6.1e-17 62.0 0.0 4.8 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG49442.1 - 2.5e-33 110.4 0.1 0.0011 19.2 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 KXG49442.1 - 2.5e-31 106.7 0.2 0.0042 17.5 0.2 9.0 9 0 0 9 9 8 7 Ankyrin repeat Ank_5 PF13857.6 KXG49442.1 - 4.4e-31 106.5 3.0 3.7e-11 43.0 0.1 7.9 2 2 6 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXG49442.1 - 6.6e-30 103.1 0.9 9.1e-11 42.1 0.0 6.6 2 2 6 8 8 8 6 Ankyrin repeats (many copies) NACHT PF05729.12 KXG49442.1 - 1.9e-09 37.7 0.2 4.6e-09 36.4 0.2 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXG49442.1 - 4.2e-07 30.5 1.1 1.3e-06 28.9 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXG49442.1 - 0.00043 20.6 0.0 0.0018 18.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXG49442.1 - 0.0012 19.3 0.1 0.026 14.9 0.0 3.3 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXG49442.1 - 0.0079 16.7 0.1 0.74 10.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KXG49442.1 - 0.052 12.7 0.0 0.15 11.2 0.0 1.8 1 1 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KXG49442.1 - 0.071 13.5 0.0 0.28 11.6 0.0 2.0 1 0 0 1 1 1 0 RNA helicase DLIC PF05783.11 KXG49442.1 - 0.14 11.0 0.0 0.28 9.9 0.0 1.5 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AMP-binding PF00501.28 KXG49443.1 - 2.5e-66 224.0 0.0 3.4e-66 223.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KXG49443.1 - 8.8e-29 100.4 0.0 1.5e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KXG49443.1 - 7e-05 22.0 0.0 0.0039 16.2 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 KXG49443.1 - 0.00081 19.7 0.1 0.0018 18.6 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KXG49443.1 - 0.028 14.3 0.0 0.11 12.4 0.0 2.0 1 1 0 1 1 1 0 KR domain Epimerase PF01370.21 KXG49443.1 - 0.16 11.4 0.0 1.1 8.7 0.0 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Cys_Met_Meta_PP PF01053.20 KXG49445.1 - 2.8e-148 493.5 0.0 3.7e-148 493.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXG49445.1 - 1.3e-11 44.4 0.3 2.4e-11 43.6 0.3 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KXG49445.1 - 3.9e-09 35.9 0.3 6.2e-09 35.3 0.3 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXG49445.1 - 2.9e-08 33.3 0.1 4.7e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KXG49445.1 - 6.8e-05 22.3 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KXG49445.1 - 0.0041 15.7 0.1 0.0058 15.2 0.1 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase CTD_bind PF04818.13 KXG49446.1 - 2.4e-08 34.7 0.0 4.5e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KXG49446.1 - 1.1e-05 25.2 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Citrate_synt PF00285.21 KXG49447.1 - 6.1e-100 334.8 0.0 7.7e-100 334.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Mito_carr PF00153.27 KXG49448.1 - 4.4e-26 90.6 4.0 6.7e-12 45.2 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Coprogen_oxidas PF01218.18 KXG49449.1 - 1.3e-135 450.9 0.0 2.5e-135 450.0 0.0 1.4 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.16 KXG49450.1 - 2.7e-51 172.1 0.2 3.2e-51 171.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KXG49450.1 - 3e-06 27.5 0.0 3.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Mito_carr PF00153.27 KXG49451.1 - 2.4e-28 97.9 1.4 7e-15 54.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein HOOK PF05622.12 KXG49452.1 - 2.6e-27 95.4 69.2 3.2e-27 95.0 38.0 3.0 1 1 1 2 2 2 1 HOOK protein CH_2 PF06294.11 KXG49452.1 - 1.6e-05 24.9 1.8 0.0081 16.3 0.2 3.3 2 0 0 2 2 2 2 CH-like domain in sperm protein TPR_MLP1_2 PF07926.12 KXG49452.1 - 0.0014 18.7 82.7 0.021 14.9 6.8 7.3 6 2 1 7 7 7 4 TPR/MLP1/MLP2-like protein ADIP PF11559.8 KXG49452.1 - 0.0065 16.6 2.5 0.0065 16.6 2.5 7.0 5 2 0 6 6 6 1 Afadin- and alpha -actinin-Binding DUF1411 PF07199.11 KXG49452.1 - 0.0092 15.7 2.4 0.069 12.8 1.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1411) ATG16 PF08614.11 KXG49452.1 - 0.016 15.5 78.2 0.063 13.5 8.0 5.7 4 2 1 5 5 5 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 KXG49452.1 - 0.017 15.0 82.8 0.29 10.9 21.7 5.3 3 1 2 5 5 5 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 KXG49452.1 - 0.029 13.2 78.7 0.11 11.4 8.6 5.2 4 1 2 6 6 6 0 Spc7 kinetochore protein HALZ PF02183.18 KXG49452.1 - 0.12 12.6 0.1 0.12 12.6 0.1 7.9 7 2 2 9 9 9 0 Homeobox associated leucine zipper Bacillus_HBL PF05791.11 KXG49452.1 - 0.12 12.2 0.2 0.12 12.2 0.2 5.9 5 2 1 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.10 KXG49452.1 - 0.58 10.3 54.9 0.19 11.9 7.0 5.7 3 2 3 6 6 6 0 Fibrinogen alpha/beta chain family HMMR_N PF15905.5 KXG49452.1 - 1.2 8.5 73.0 0.44 10.0 39.4 3.6 2 2 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Filament PF00038.21 KXG49452.1 - 2.3 7.7 62.9 1.2 8.7 28.2 5.2 3 1 1 4 4 4 0 Intermediate filament protein DUF4407 PF14362.6 KXG49452.1 - 3.3 7.0 53.0 0.86 8.9 16.9 4.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 KXG49452.1 - 7.4 7.0 61.2 2 8.8 4.6 7.8 7 1 0 8 8 8 0 Csm1 N-terminal domain UPF0242 PF06785.11 KXG49452.1 - 9.6 6.3 78.5 0.14 12.2 5.8 5.9 3 1 1 4 4 3 0 Uncharacterised protein family (UPF0242) N-terminus Inhibitor_I9 PF05922.16 KXG49453.1 - 0.1 13.3 0.0 0.14 12.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase inhibitor I9 CFIA_Pcf11 PF11526.8 KXG49454.1 - 4.4e-10 39.9 0.4 1.2e-09 38.5 0.4 1.8 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 KXG49454.1 - 6.8e-06 26.8 0.0 1.9e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-ISL3 PF14690.6 KXG49454.1 - 0.18 12.5 1.4 0.27 11.9 0.3 1.8 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf_UBZ PF18439.1 KXG49454.1 - 0.34 10.5 4.6 1.2 8.8 0.6 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_4 PF13894.6 KXG49454.1 - 0.69 10.9 2.9 37 5.5 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KXG49454.1 - 1.6 8.7 4.9 18 5.4 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type GFO_IDH_MocA PF01408.22 KXG49455.1 - 5.8e-17 62.6 0.1 8.2e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXG49455.1 - 0.0067 17.1 0.1 0.01 16.5 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ADK PF00406.22 KXG49456.1 - 1.3e-59 200.6 0.0 1.7e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXG49456.1 - 4.7e-23 82.1 0.1 8.3e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 KXG49456.1 - 1.7e-16 59.9 0.0 3.8e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KXG49456.1 - 7.7e-08 33.0 0.0 1.4e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXG49456.1 - 4.5e-05 23.6 0.0 8.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain TSC22 PF01166.18 KXG49456.1 - 0.069 13.5 0.2 0.16 12.3 0.2 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Thymidylate_kin PF02223.17 KXG49456.1 - 0.072 12.8 0.0 0.17 11.5 0.0 1.5 2 0 0 2 2 2 0 Thymidylate kinase AAA_28 PF13521.6 KXG49456.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran_CTD PF16326.5 KXG49456.1 - 0.18 12.1 0.2 0.18 12.1 0.2 2.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain MitMem_reg PF13012.6 KXG49457.1 - 1.8e-37 128.2 0.3 3.1e-37 127.4 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXG49457.1 - 6.4e-32 110.0 0.0 1.4e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease NARP1 PF12569.8 KXG49457.1 - 0.12 11.2 4.3 0.21 10.4 4.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 tRNA_bind_2 PF13725.6 KXG49457.1 - 0.37 10.5 4.5 0.54 9.9 4.5 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain UCH PF00443.29 KXG49458.1 - 5.8e-16 58.8 0.0 9.3e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXG49458.1 - 1.3e-05 24.9 0.1 2.8e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Myb_DNA-binding PF00249.31 KXG49459.1 - 3.5e-14 52.7 1.9 9.2e-11 41.8 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXG49459.1 - 9.2e-06 25.8 3.3 0.011 15.9 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain AGOG PF09171.10 KXG49459.1 - 0.13 11.6 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 N-glycosylase/DNA lyase Methyltransf_11 PF08241.12 KXG49460.1 - 1.7e-14 54.2 0.0 2.9e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG49460.1 - 4.4e-11 43.3 0.1 8.3e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG49460.1 - 1.7e-06 28.0 0.0 5.8e-06 26.2 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG49460.1 - 1.2e-05 26.0 0.0 2.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG49460.1 - 1.5e-05 24.8 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KXG49460.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 KXG49460.1 - 0.044 12.7 0.1 0.14 11.0 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 KXG49460.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase CAP_GLY PF01302.25 KXG49461.1 - 1.3e-25 89.2 0.0 1.9e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KXG49461.1 - 5.3e-14 52.4 0.0 8.5e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KXG49461.1 - 0.00021 21.0 0.0 0.001 18.8 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family CENP-C_C PF11699.8 KXG49462.1 - 5.1e-37 126.0 0.7 9.8e-37 125.0 0.7 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 KXG49462.1 - 9e-35 120.3 3.7 9e-35 120.3 3.7 3.6 3 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 KXG49462.1 - 1.2e-06 28.1 0.0 2.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXG49462.1 - 0.038 13.6 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Cupin RNase_HII PF01351.18 KXG49463.1 - 2.4e-47 161.3 0.0 3.3e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII Pex16 PF08610.10 KXG49464.1 - 3.3e-96 322.3 0.3 3.7e-96 322.1 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) SAE2 PF08573.10 KXG49465.1 - 5.3e-38 130.5 0.1 5.3e-38 130.5 0.1 3.6 2 1 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus HlyD_2 PF12700.7 KXG49465.1 - 0.044 12.5 0.1 0.07 11.9 0.1 1.3 1 0 0 1 1 1 0 HlyD family secretion protein GAS PF13851.6 KXG49465.1 - 0.21 10.9 11.3 0.021 14.2 4.1 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Histone_HNS PF00816.21 KXG49465.1 - 1.7 9.5 8.4 2.2 9.1 0.6 4.1 3 1 0 3 3 3 0 H-NS histone family zf-CCHC PF00098.23 KXG49467.1 - 1.2e-50 167.4 63.6 2.3e-09 36.9 2.0 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KXG49467.1 - 1.8e-13 50.0 40.9 0.0055 16.4 0.7 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KXG49467.1 - 4.7e-06 26.4 53.0 0.0051 16.8 1.6 6.8 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 KXG49467.1 - 0.00023 20.8 43.9 0.61 9.8 0.5 7.0 5 2 2 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 KXG49467.1 - 0.00086 19.1 47.1 0.038 13.8 0.9 6.9 4 2 3 7 7 7 4 Zinc knuckle zf-CCHC_2 PF13696.6 KXG49467.1 - 0.012 15.4 1.5 0.012 15.4 1.5 7.4 7 0 0 7 7 7 0 Zinc knuckle UPF0061 PF02696.14 KXG49468.1 - 1.4e-129 433.0 0.0 1.7e-129 432.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Aldo_ket_red PF00248.21 KXG49469.1 - 4.2e-40 137.8 0.5 1.9e-38 132.4 0.5 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family YflT PF11181.8 KXG49469.1 - 0.11 13.0 0.4 0.24 11.9 0.2 1.7 2 0 0 2 2 2 0 Heat induced stress protein YflT Choline_transpo PF04515.12 KXG49471.1 - 7.4e-23 81.2 19.7 7.4e-23 81.2 19.7 2.5 2 1 0 2 2 2 2 Plasma-membrane choline transporter Ras PF00071.22 KXG49472.1 - 1.4e-47 161.3 0.0 8.6e-37 126.2 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KXG49472.1 - 4.3e-28 97.9 0.0 1.7e-17 63.7 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG49472.1 - 4.7e-11 42.4 0.0 1.6e-10 40.7 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXG49472.1 - 2e-08 34.0 0.0 1.2e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXG49472.1 - 0.0006 19.9 0.0 0.0035 17.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXG49472.1 - 0.00067 19.1 0.0 0.0018 17.6 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KXG49472.1 - 0.0064 16.4 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KXG49472.1 - 0.0072 16.6 0.0 0.022 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXG49472.1 - 0.014 15.1 0.1 0.099 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Flu_M1_C PF08289.11 KXG49472.1 - 0.035 14.3 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain PMT PF02366.18 KXG49473.1 - 1.3e-71 241.1 14.7 1.3e-71 241.1 14.7 2.8 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXG49473.1 - 6.5e-63 211.9 13.9 6.5e-63 211.9 13.9 2.3 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXG49473.1 - 1.1e-36 126.4 0.2 1.7e-36 125.8 0.2 1.2 1 0 0 1 1 1 1 MIR domain Sugar_tr PF00083.24 KXG49474.1 - 1.2e-94 317.8 14.1 7.1e-93 311.9 14.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG49474.1 - 6.5e-23 81.2 31.9 2.5e-20 72.7 25.4 3.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.27 KXG49474.1 - 4.6e-18 64.9 0.3 1.4e-12 47.4 0.1 3.2 2 1 0 2 2 2 2 Mitochondrial carrier protein MFS_2 PF13347.6 KXG49474.1 - 1.5e-05 23.8 19.7 3.1e-05 22.7 7.6 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein FACT-Spt16_Nlob PF14826.6 KXG49475.1 - 2.5e-56 189.9 0.2 1.1e-55 187.9 0.2 2.2 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 KXG49475.1 - 5.2e-56 189.0 0.0 1.5e-55 187.6 0.0 1.9 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 KXG49475.1 - 2.1e-28 99.4 0.0 3.8e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KXG49475.1 - 2.1e-14 53.7 0.2 5.2e-14 52.4 0.1 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Arc_PepC PF06819.11 KXG49475.1 - 0.042 14.0 0.7 2.3 8.4 0.0 3.1 3 0 0 3 3 3 0 Archaeal Peptidase A24 C-terminal Domain CDC50 PF03381.15 KXG49476.1 - 5.2e-94 314.9 0.0 7e-94 314.5 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Peptidase_M43 PF05572.13 KXG49476.1 - 5.4e-10 39.4 0.0 1.5e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KXG49476.1 - 1.3e-05 25.4 4.8 3.3e-05 24.1 4.3 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KXG49476.1 - 0.00079 19.9 0.1 0.021 15.4 0.1 2.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KXG49476.1 - 0.15 11.9 0.9 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like SWIRM PF04433.17 KXG49477.1 - 3.5e-12 46.5 0.0 7.5e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain WD40 PF00400.32 KXG49478.1 - 1.7e-17 63.4 6.3 0.0036 18.1 0.0 8.9 10 0 0 10 10 10 5 WD domain, G-beta repeat DUF742 PF05331.11 KXG49478.1 - 0.016 15.0 0.1 0.22 11.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF742) Neugrin PF06413.11 KXG49480.1 - 3.9e-12 46.7 0.1 3.9e-12 46.7 0.1 2.2 1 1 1 2 2 2 1 Neugrin MRP-L20 PF12824.7 KXG49480.1 - 0.00015 22.0 10.0 0.00015 22.0 10.0 2.5 1 1 2 3 3 3 1 Mitochondrial ribosomal protein subunit L20 HTH_11 PF08279.12 KXG49480.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 HTH domain Acyl-CoA_dh_N PF02771.16 KXG49480.1 - 4 8.1 6.6 1.9 9.1 0.2 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Rgp1 PF08737.10 KXG49481.1 - 1.1e-137 459.7 0.0 1.8e-137 458.9 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 KXG49481.1 - 3.2e-05 24.0 0.0 0.00011 22.2 0.0 1.9 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KXG49481.1 - 0.052 14.0 0.0 0.35 11.3 0.0 2.3 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Mob1_phocein PF03637.17 KXG49482.1 - 9.6e-74 247.0 0.1 1.3e-73 246.6 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.18 KXG49483.1 - 5.5e-43 147.1 3.5 6.4e-43 146.8 3.5 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit ACT_6 PF13740.6 KXG49483.1 - 0.11 12.5 0.1 1.8 8.6 0.0 2.7 2 1 1 3 3 3 0 ACT domain Glyco_hydro_63 PF03200.16 KXG49484.1 - 1.4e-05 24.1 11.1 0.00017 20.5 0.2 4.0 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain OrfB_IS605 PF01385.19 KXG49485.1 - 0.014 15.6 0.5 0.018 15.2 0.5 1.2 1 0 0 1 1 1 0 Probable transposase FAM76 PF16046.5 KXG49485.1 - 0.022 14.1 2.7 0.026 13.9 2.7 1.2 1 0 0 1 1 1 0 FAM76 protein DUF4446 PF14584.6 KXG49485.1 - 0.087 12.8 1.1 0.11 12.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) SlyX PF04102.12 KXG49485.1 - 0.16 12.6 8.7 0.28 11.8 8.7 1.5 1 1 0 1 1 1 0 SlyX DUF4407 PF14362.6 KXG49485.1 - 0.4 10.0 6.3 0.49 9.7 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pox_A_type_inc PF04508.12 KXG49485.1 - 0.46 10.4 6.4 1.1 9.2 6.4 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat RIC3 PF15361.6 KXG49485.1 - 4 7.8 7.2 0.74 10.2 3.3 1.8 1 1 1 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Bromodomain PF00439.25 KXG49486.1 - 5.8e-08 32.7 0.0 5.1e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 Bromodomain Herpes_UL25 PF01499.16 KXG49486.1 - 0.048 12.2 0.2 0.11 11.0 0.2 1.5 1 0 0 1 1 1 0 Herpesvirus UL25 family Diphthamide_syn PF01866.17 KXG49487.1 - 1.6e-117 392.3 0.0 2e-117 391.9 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein HMGL-like PF00682.19 KXG49488.1 - 4.7e-46 157.5 0.2 7e-46 156.9 0.2 1.3 1 0 0 1 1 1 1 HMGL-like PE PF00934.20 KXG49488.1 - 0.18 12.1 0.2 0.18 12.1 0.2 2.2 2 0 0 2 2 2 0 PE family DUF1674 PF07896.12 KXG49489.1 - 5.2e-19 68.5 4.1 5.6e-19 68.4 3.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Aminotran_3 PF00202.21 KXG49490.1 - 2.1e-112 375.7 0.0 2.7e-112 375.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXG49490.1 - 0.00089 18.5 0.0 0.0018 17.5 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II APH PF01636.23 KXG49491.1 - 2.6e-10 40.6 0.2 7e-10 39.2 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG49491.1 - 0.00068 19.3 0.3 0.00068 19.3 0.3 1.9 2 1 1 3 3 3 1 Choline/ethanolamine kinase CLN3 PF02487.17 KXG49492.1 - 1.1e-155 518.6 2.1 1.9e-155 517.9 2.1 1.3 1 0 0 1 1 1 1 CLN3 protein Abhydrolase_3 PF07859.13 KXG49492.1 - 6.6e-32 111.1 0.0 3.2e-21 76.2 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold MFS_1 PF07690.16 KXG49492.1 - 0.00027 20.0 21.3 0.0024 16.8 19.8 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Say1_Mug180 PF10340.9 KXG49492.1 - 0.18 10.6 0.0 0.61 8.9 0.0 1.7 2 0 0 2 2 2 0 Steryl acetyl hydrolase DLH PF01738.18 KXG49493.1 - 5.2e-14 52.3 0.0 6.2e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family F-box PF00646.33 KXG49494.1 - 0.00032 20.5 2.0 0.00058 19.7 0.6 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXG49494.1 - 0.0065 16.3 0.3 0.018 14.9 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 KXG49494.1 - 0.056 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 F-box MFS_1 PF07690.16 KXG49495.1 - 7.2e-36 123.8 61.8 3.7e-26 91.9 31.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 KXG49496.1 - 1.4e-23 83.3 7.0 2.4e-09 37.7 0.0 8.6 1 1 9 12 12 12 9 Ankyrin repeats (3 copies) Velvet PF11754.8 KXG49496.1 - 4.5e-23 82.5 0.0 7.6e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Velvet factor NACHT_N PF17100.5 KXG49496.1 - 4.7e-10 39.7 0.2 1.6e-09 38.0 0.2 1.9 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank PF00023.30 KXG49496.1 - 8.5e-08 32.3 9.9 0.57 10.7 0.0 11.2 14 2 0 14 14 13 1 Ankyrin repeat Ank_4 PF13637.6 KXG49496.1 - 1.2e-07 32.1 0.2 0.0001 22.8 0.0 5.2 5 1 0 5 5 4 1 Ankyrin repeats (many copies) AAA_22 PF13401.6 KXG49496.1 - 1.2e-05 25.6 0.0 6.4e-05 23.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KXG49496.1 - 1.3e-05 25.2 0.0 3.7e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXG49496.1 - 3.7e-05 24.2 1.3 0.00081 19.8 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain Ank_3 PF13606.6 KXG49496.1 - 5.3e-05 23.3 3.1 0.23 12.1 0.0 8.2 11 0 0 11 11 7 1 Ankyrin repeat AAA_assoc_C PF09821.9 KXG49496.1 - 0.015 15.8 4.9 0.48 11.0 0.4 3.4 2 1 1 3 3 3 0 C-terminal AAA-associated domain RNA_helicase PF00910.22 KXG49496.1 - 0.022 15.1 0.0 0.17 12.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase KAP_NTPase PF07693.14 KXG49496.1 - 0.076 12.2 1.1 0.97 8.6 0.2 2.3 1 1 0 2 2 2 0 KAP family P-loop domain ATP1G1_PLM_MAT8 PF02038.16 KXG49497.1 - 0.49 9.9 3.7 1.6 8.2 0.1 2.8 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family GWT1 PF06423.12 KXG49497.1 - 5.4 7.1 6.2 13 5.9 6.1 1.7 1 1 0 1 1 1 0 GWT1 NACHT PF05729.12 KXG49498.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Fungal_trans PF04082.18 KXG49499.1 - 2.6e-13 49.6 0.1 3e-13 49.4 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.21 KXG49501.1 - 2.4e-98 329.8 42.1 2.8e-98 329.6 42.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG49501.1 - 1.5e-23 83.3 43.8 1.8e-23 83.1 43.8 1.1 1 0 0 1 1 1 1 Amino acid permease Hydrolase PF00702.26 KXG49502.1 - 1.7e-07 31.8 0.0 4.9e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXG49502.1 - 0.00086 19.4 0.0 0.0012 19.0 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KXG49502.1 - 0.033 14.6 2.0 0.057 13.8 0.6 2.0 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase RPAP1_C PF08620.10 KXG49502.1 - 0.075 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 RPAP1-like, C-terminal Hydrolase_6 PF13344.6 KXG49502.1 - 0.1 12.8 0.0 8.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DAO PF01266.24 KXG49503.1 - 6.5e-47 160.8 0.5 9e-47 160.3 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXG49503.1 - 0.0093 15.1 1.0 0.26 10.3 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KXG49503.1 - 0.021 14.8 4.5 0.24 11.4 0.2 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXG49503.1 - 0.038 13.2 1.7 8.6 5.5 1.4 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG49503.1 - 0.12 11.6 0.1 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family MIP PF00230.20 KXG49504.1 - 1.6e-43 149.0 9.2 2.3e-43 148.5 9.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein ThrE PF06738.12 KXG49504.1 - 4.6 6.5 6.3 6.8 6.0 4.8 2.1 1 1 1 2 2 2 0 Putative threonine/serine exporter Rxt3 PF08642.10 KXG49505.1 - 4.5e-42 143.8 0.1 1.4e-41 142.3 0.0 1.9 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KXG49505.1 - 0.002 18.2 0.0 0.0063 16.6 0.0 1.8 1 0 0 1 1 1 1 LCCL domain Carn_acyltransf PF00755.20 KXG49506.1 - 3.2e-207 689.8 0.0 3.7e-207 689.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Sec62 PF03839.16 KXG49508.1 - 8.6e-78 260.8 1.0 8.6e-78 260.8 1.0 2.0 2 0 0 2 2 2 1 Translocation protein Sec62 Pterin_4a PF01329.19 KXG49509.1 - 5.4e-09 36.1 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase MFS_1 PF07690.16 KXG49510.1 - 1.9e-23 83.0 29.0 1e-22 80.6 26.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2198 PF09964.9 KXG49510.1 - 0.13 12.3 2.4 10 6.3 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) DMSP_lyase PF16867.5 KXG49511.1 - 0.009 15.7 0.3 0.019 14.6 0.3 1.4 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase DUF2046 PF09755.9 KXG49511.1 - 0.017 14.3 0.9 0.017 14.3 0.9 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DASH_Spc34 PF08657.10 KXG49511.1 - 0.045 13.5 3.7 0.45 10.3 1.5 2.1 2 0 0 2 2 2 0 DASH complex subunit Spc34 SlyX PF04102.12 KXG49511.1 - 0.099 13.3 8.6 5.5 7.7 0.0 2.5 2 0 0 2 2 2 0 SlyX Atg14 PF10186.9 KXG49511.1 - 0.12 11.4 4.9 0.09 11.8 0.5 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMCO5 PF14992.6 KXG49511.1 - 0.18 11.3 2.5 0.64 9.6 2.5 1.8 1 1 0 1 1 1 0 TMCO5 family DUF16 PF01519.16 KXG49511.1 - 0.36 11.4 4.1 2 8.9 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 MerR-DNA-bind PF09278.11 KXG49511.1 - 1.3 9.6 8.7 0.58 10.7 0.3 2.4 2 0 0 2 2 2 0 MerR, DNA binding DUF2968 PF11180.8 KXG49511.1 - 1.7 8.2 16.0 0.46 10.1 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) TERB2 PF15101.6 KXG49511.1 - 1.9 8.5 6.2 23 5.0 2.5 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Spc24 PF08286.11 KXG49511.1 - 4 7.7 6.8 35 4.7 0.0 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.15 KXG49511.1 - 4 7.3 9.9 0.58 10.0 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator Pyr_redox_2 PF07992.14 KXG49513.1 - 5.8e-10 38.9 0.0 1.2e-09 37.8 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG49513.1 - 0.00033 20.8 0.0 0.00093 19.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KXG49513.1 - 0.021 15.2 0.0 3.6 8.1 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 KXG49513.1 - 0.022 13.5 0.0 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 KXG49513.1 - 0.035 14.1 0.0 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXG49513.1 - 0.053 12.6 0.1 0.31 10.0 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 KXG49513.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KXG49513.1 - 0.2 12.2 0.0 4.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cerato-platanin PF07249.12 KXG49514.1 - 2.9e-46 156.4 0.6 3.4e-46 156.2 0.6 1.1 1 0 0 1 1 1 1 Cerato-platanin DAO PF01266.24 KXG49515.1 - 5.1e-28 98.7 0.0 6.4e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG49515.1 - 6e-08 32.3 0.0 0.00036 19.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG49515.1 - 5.6e-07 29.7 0.0 1.6e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXG49515.1 - 7.6e-07 29.6 0.0 4e-06 27.3 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG49515.1 - 0.00038 20.5 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.22 KXG49515.1 - 0.00058 19.1 0.0 0.076 12.1 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 KXG49515.1 - 0.00097 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KXG49515.1 - 0.0016 18.6 0.0 0.0035 17.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KXG49515.1 - 0.0017 18.4 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.14 KXG49515.1 - 0.0037 16.0 0.0 0.068 11.9 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KXG49515.1 - 0.0093 15.1 0.0 0.024 13.7 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 KXG49515.1 - 0.014 15.7 0.1 0.033 14.4 0.0 1.6 2 0 0 2 2 1 0 TrkA-N domain Adeno_PVIII PF01310.18 KXG49515.1 - 0.017 14.7 0.1 0.047 13.3 0.0 1.7 2 0 0 2 2 2 0 Adenovirus hexon associated protein, protein VIII ApbA PF02558.16 KXG49515.1 - 0.032 13.9 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KXG49515.1 - 0.038 13.3 0.0 0.76 9.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG49515.1 - 0.04 13.1 0.0 0.08 12.1 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) IlvN PF07991.12 KXG49515.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 KXG49515.1 - 0.094 12.8 0.0 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KXG49515.1 - 0.11 11.8 0.0 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Amidase PF01425.21 KXG49516.1 - 1.1e-32 113.7 0.4 2.1e-32 112.7 0.4 1.4 1 0 0 1 1 1 1 Amidase adh_short PF00106.25 KXG49517.1 - 1.5e-25 89.8 0.0 2.1e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG49517.1 - 4.3e-21 75.5 0.0 5.5e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG49517.1 - 0.00017 21.6 0.0 0.0003 20.8 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXG49517.1 - 0.01 15.8 0.3 0.019 14.8 0.3 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Amino_oxidase PF01593.24 KXG49518.1 - 3.6e-32 112.3 0.2 5.1e-32 111.7 0.2 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXG49518.1 - 3.6e-05 23.9 0.0 0.0001 22.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG49518.1 - 0.0072 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG49518.1 - 0.046 13.3 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXG49518.1 - 0.085 12.1 0.4 0.14 11.3 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KXG49518.1 - 0.09 12.0 0.2 0.15 11.3 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_3 PF07859.13 KXG49519.1 - 7.1e-41 140.4 0.1 1.2e-32 113.5 0.0 3.0 3 0 0 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXG49519.1 - 4.7e-14 52.0 0.0 7.4e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KXG49519.1 - 0.015 14.6 0.0 0.036 13.3 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 COesterase PF00135.28 KXG49519.1 - 0.045 12.6 0.0 0.12 11.2 0.0 1.6 1 1 0 1 1 1 0 Carboxylesterase family ParA PF10609.9 KXG49520.1 - 2.4e-84 282.6 0.0 7.5e-84 281.0 0.0 1.7 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXG49520.1 - 8.7e-13 48.4 0.0 1.5e-11 44.4 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KXG49520.1 - 2.1e-09 37.6 1.6 1.8e-08 34.5 1.6 2.0 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KXG49520.1 - 2.3e-05 23.8 0.1 3.7e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KXG49520.1 - 0.001 18.4 0.9 0.0042 16.3 0.3 2.1 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.6 KXG49520.1 - 0.0015 18.2 0.0 0.0033 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 KXG49520.1 - 0.12 11.8 0.0 0.54 9.6 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family TRAUB PF08164.12 KXG49521.1 - 3.1e-29 101.3 0.0 3.1e-29 101.3 0.0 3.0 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KXG49521.1 - 5.4e-27 95.2 2.2 5.4e-27 95.2 2.2 2.8 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor Fungal_trans_2 PF11951.8 KXG49523.1 - 1.5e-08 33.8 0.4 1.9e-08 33.5 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain GFO_IDH_MocA PF01408.22 KXG49524.1 - 1.2e-21 77.7 0.1 2e-21 77.0 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXG49524.1 - 1.8e-06 27.9 0.0 3.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DapB_N PF01113.20 KXG49524.1 - 0.0042 17.2 0.0 0.07 13.3 0.0 2.4 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DUF2433 PF10360.9 KXG49525.1 - 1e-47 161.3 0.0 1.6e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.7 KXG49525.1 - 0.00073 19.8 0.0 0.003 17.8 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KXG49525.1 - 0.00089 19.8 0.0 0.0022 18.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FoP_duplication PF13865.6 KXG49525.1 - 2.6 8.6 14.4 9.4 6.9 14.4 2.0 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 PAP1 PF08601.10 KXG49526.1 - 9.6e-128 427.0 35.8 1.7e-115 386.7 11.7 3.9 2 1 2 4 4 4 3 Transcription factor PAP1 bZIP_1 PF00170.21 KXG49526.1 - 1.8e-07 31.1 9.5 3.7e-07 30.1 9.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor ERM PF00769.19 KXG49526.1 - 0.00022 21.2 0.4 0.00043 20.2 0.4 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family MbeD_MobD PF04899.12 KXG49526.1 - 0.0026 17.8 2.0 0.005 16.9 2.0 1.4 1 0 0 1 1 1 1 MbeD/MobD like SHE3 PF17078.5 KXG49526.1 - 0.029 14.1 3.3 0.051 13.3 3.3 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 KXG49526.1 - 0.046 14.2 9.8 0.089 13.3 9.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Adaptin_binding PF10199.9 KXG49526.1 - 0.078 13.6 3.1 0.086 13.4 0.5 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 HAUS-augmin3 PF14932.6 KXG49526.1 - 0.32 10.5 3.7 0.54 9.8 3.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 bZIP_2 PF07716.15 KXG49526.1 - 0.33 11.0 12.9 1.6 8.9 12.9 2.0 1 1 0 1 1 1 0 Basic region leucine zipper ABC_tran_Xtn PF12848.7 KXG49526.1 - 3.3 7.8 7.0 7 6.8 7.0 1.5 1 0 0 1 1 1 0 ABC transporter Macoilin PF09726.9 KXG49526.1 - 7.3 5.0 10.2 3.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Macoilin family Tudor_3 PF18115.1 KXG49527.1 - 9.8e-08 31.7 0.0 1.8e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KXG49527.1 - 0.0013 18.7 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 KXG49527.1 - 0.075 12.8 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain TUDOR PF00567.24 KXG49527.1 - 0.088 12.8 0.0 0.31 11.1 0.0 1.8 1 1 1 2 2 2 0 Tudor domain Patched PF02460.18 KXG49528.1 - 4e-75 253.5 11.1 1.9e-49 168.6 0.1 2.2 2 0 0 2 2 2 2 Patched family NPC1_N PF16414.5 KXG49528.1 - 1.4e-68 231.1 5.0 5.2e-63 212.9 2.2 2.2 1 1 1 2 2 2 2 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 KXG49528.1 - 7.4e-52 175.2 7.7 7.4e-52 175.2 7.7 3.4 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KXG49528.1 - 1.2e-05 24.4 9.5 1.2e-05 24.4 9.5 3.4 3 1 0 3 3 3 1 MMPL family REV1_C PF16727.5 KXG49528.1 - 0.15 12.5 0.2 0.33 11.4 0.2 1.5 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain HEAT_EZ PF13513.6 KXG49529.1 - 7e-17 61.6 9.6 5.5e-06 26.8 0.0 8.3 9 1 0 9 9 8 4 HEAT-like repeat HEAT PF02985.22 KXG49529.1 - 7.2e-17 60.0 1.5 0.00033 20.7 0.1 8.6 9 0 0 9 9 7 3 HEAT repeat HEAT_2 PF13646.6 KXG49529.1 - 3e-15 56.4 5.4 3.2e-05 24.2 0.0 7.7 7 3 4 11 11 10 5 HEAT repeats Vac14_Fab1_bd PF12755.7 KXG49529.1 - 1.3e-10 41.8 0.4 0.06 13.9 0.0 6.3 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KXG49529.1 - 2.4e-10 40.0 4.9 3.9e-05 22.9 0.9 4.0 3 1 1 4 4 4 3 Interferon-related developmental regulator (IFRD) IBN_N PF03810.19 KXG49529.1 - 1.1e-09 38.0 3.8 3e-08 33.5 0.3 3.5 4 0 0 4 4 3 1 Importin-beta N-terminal domain Cnd1 PF12717.7 KXG49529.1 - 1.4e-09 38.2 2.0 0.029 14.4 0.0 4.5 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 KXG49529.1 - 6.2e-09 35.5 2.1 0.00017 20.8 0.0 3.6 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KXG49529.1 - 8.4e-07 28.8 0.0 0.007 15.9 0.0 3.4 3 0 0 3 3 3 2 CLASP N terminal UME PF08064.13 KXG49529.1 - 1.3e-05 25.1 0.1 0.91 9.5 0.1 5.1 4 2 0 4 4 4 2 UME (NUC010) domain Arm PF00514.23 KXG49529.1 - 5.5e-05 23.1 2.6 0.97 9.6 0.0 5.8 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KXG49529.1 - 8.6e-05 22.7 1.3 6 7.1 0.4 5.0 4 1 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KXG49529.1 - 9.7e-05 21.1 1.5 0.63 8.5 0.0 4.0 3 1 1 4 4 4 2 Adaptin N terminal region ParcG PF10274.9 KXG49529.1 - 0.0058 16.8 1.7 1.4 9.0 0.2 3.6 3 1 1 4 4 4 1 Parkin co-regulated protein V-ATPase_H_C PF11698.8 KXG49529.1 - 0.0076 16.3 0.7 13 5.9 0.1 4.2 4 0 0 4 4 4 0 V-ATPase subunit H RIX1 PF08167.12 KXG49529.1 - 0.021 14.6 0.2 1.6 8.4 0.0 3.5 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis NUC173 PF08161.12 KXG49529.1 - 0.056 13.1 0.0 29 4.3 0.0 4.9 5 1 1 6 6 6 0 NUC173 domain UNC45-central PF11701.8 KXG49529.1 - 0.065 13.2 0.2 3.5 7.6 0.1 3.8 4 1 1 5 5 5 0 Myosin-binding striated muscle assembly central p450 PF00067.22 KXG49530.1 - 3.1e-50 171.3 0.0 2.7e-45 155.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF3231 PF11553.8 KXG49530.1 - 0.068 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) TRAM1 PF08390.11 KXG49530.1 - 0.081 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 TRAM1-like protein Fungal_trans PF04082.18 KXG49531.1 - 1.2e-11 44.2 0.1 3.6e-11 42.6 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KXG49531.1 - 0.032 13.1 0.1 0.54 9.0 0.0 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain Med7 PF05983.11 KXG49532.1 - 3.7e-61 206.5 4.3 4.8e-61 206.2 4.3 1.1 1 0 0 1 1 1 1 MED7 protein Glyco_hydro_61 PF03443.14 KXG49532.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 PAP2 PF01569.21 KXG49533.1 - 4.5e-28 97.7 0.8 4.5e-28 97.7 0.8 1.8 2 1 0 2 2 2 1 PAP2 superfamily DUF2933 PF11666.8 KXG49533.1 - 0.049 13.7 0.4 0.049 13.7 0.4 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2933) RseC_MucC PF04246.12 KXG49533.1 - 1.2 9.1 7.0 3.1 7.8 0.6 3.0 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC tRNA-synt_2c PF01411.19 KXG49534.1 - 2.8e-11 42.7 0.2 3.6e-11 42.3 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KXG49534.1 - 3.6e-06 27.0 0.3 8.4e-06 25.8 0.3 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Cu_amine_oxid PF01179.20 KXG49535.1 - 3.8e-158 526.7 0.0 5.5e-158 526.2 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Fungal_trans_2 PF11951.8 KXG49535.1 - 5e-75 252.7 1.5 7.4e-75 252.1 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Polysacc_deac_1 PF01522.21 KXG49535.1 - 1.2e-16 60.7 0.0 2.9e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXG49535.1 - 6.6e-08 32.5 0.0 1.6e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Cu_amine_oxidN2 PF02727.16 KXG49535.1 - 3e-05 24.2 0.1 6.1e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KXG49535.1 - 0.0099 16.3 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain F-actin_cap_A PF01267.17 KXG49537.1 - 1.6e-95 319.5 0.0 1.8e-95 319.4 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit PEX11 PF05648.14 KXG49538.1 - 5.8e-32 111.0 0.1 6.4e-32 110.8 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) 2-Hacid_dh_C PF02826.19 KXG49541.1 - 5.4e-46 156.2 0.0 8.6e-46 155.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXG49541.1 - 5.7e-08 32.5 0.0 7.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXG49541.1 - 0.025 14.8 0.1 0.044 13.9 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Acetyltransf_10 PF13673.7 KXG49542.1 - 1.2e-06 28.5 0.0 2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXG49542.1 - 1.8e-06 28.3 0.0 2.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG49542.1 - 6.3e-05 23.2 0.0 8.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KXG49542.1 - 0.01 15.9 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain p450 PF00067.22 KXG49543.1 - 1.2e-36 126.5 0.0 1.8e-36 125.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_25 PF01183.20 KXG49544.1 - 7.1e-41 140.3 0.1 8.2e-41 140.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Fungal_trans PF04082.18 KXG49545.1 - 7.6e-21 74.3 0.0 1.4e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_1 PF01979.20 KXG49546.1 - 6.8e-60 203.2 0.0 8.7e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXG49546.1 - 4.3e-11 42.9 0.2 5.6e-08 32.7 0.0 2.5 2 1 1 3 3 3 2 Amidohydrolase family A_deaminase PF00962.22 KXG49546.1 - 9.2e-05 21.9 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase Dpy-30 PF05186.13 KXG49546.1 - 0.048 13.4 0.1 0.14 11.8 0.1 1.8 1 0 0 1 1 1 0 Dpy-30 motif OPT PF03169.15 KXG49547.1 - 1.5e-166 555.7 57.5 1.7e-166 555.5 57.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DAO PF01266.24 KXG49548.1 - 1.9e-27 96.8 0.1 2.6e-27 96.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF604 PF04646.12 KXG49548.1 - 0.0049 16.3 0.1 0.0075 15.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Pyr_redox_2 PF07992.14 KXG49548.1 - 0.012 14.9 0.1 0.022 14.0 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXG49548.1 - 0.04 13.6 0.7 0.09 12.4 0.7 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 KXG49548.1 - 0.083 13.1 0.6 0.22 11.8 0.6 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 KXG49548.1 - 0.22 10.9 0.3 0.43 9.9 0.3 1.4 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.18 KXG49548.1 - 0.24 11.3 0.1 0.37 10.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HATPase_c PF02518.26 KXG49549.1 - 3.5e-25 88.7 0.0 1e-24 87.2 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXG49549.1 - 4.2e-25 88.1 0.5 9.4e-25 87.0 0.5 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXG49549.1 - 1.9e-16 59.8 0.3 4.6e-16 58.6 0.3 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KXG49549.1 - 2.8e-13 50.0 0.0 1e-11 45.0 0.0 2.7 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 KXG49549.1 - 1.5e-11 44.3 0.0 1e-06 28.7 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 KXG49549.1 - 6.1e-11 42.5 0.0 0.00038 20.7 0.0 2.3 2 0 0 2 2 2 2 PAS fold Pro-kuma_activ PF09286.11 KXG49550.1 - 1.7e-31 109.4 0.2 2.5e-16 60.3 0.0 2.9 3 1 1 4 4 4 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXG49550.1 - 0.0017 17.6 0.6 0.0033 16.7 0.6 1.4 1 0 0 1 1 1 1 Subtilase family Aldo_ket_red PF00248.21 KXG49551.1 - 5e-37 127.7 0.0 2.7e-36 125.3 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Recep_L_domain PF01030.24 KXG49552.1 - 0.0001 22.4 0.1 0.0069 16.5 0.1 2.2 1 1 0 1 1 1 1 Receptor L domain Ecm33 PF12454.8 KXG49552.1 - 0.00017 21.7 0.4 0.00017 21.7 0.4 2.6 1 1 2 3 3 3 1 GPI-anchored cell wall organization protein Amidase PF01425.21 KXG49553.1 - 4.4e-87 292.9 0.0 5.9e-87 292.5 0.0 1.2 1 0 0 1 1 1 1 Amidase Lipase_GDSL_2 PF13472.6 KXG49554.1 - 6.4e-11 43.0 0.8 8.5e-11 42.6 0.8 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXG49554.1 - 2e-07 31.2 0.2 2.9e-07 30.7 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Thiolase_N PF00108.23 KXG49555.1 - 5.9e-15 55.3 0.0 8.2e-13 48.3 0.0 2.2 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXG49555.1 - 7.8e-11 41.7 1.2 1.4e-09 37.6 0.0 2.9 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KXG49555.1 - 4.7e-06 26.3 0.0 0.00028 20.7 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KXG49555.1 - 0.00016 21.4 0.4 0.00042 20.0 0.4 1.6 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 KXG49555.1 - 0.0049 15.6 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) GFA PF04828.14 KXG49556.1 - 1.5e-09 38.1 0.1 1.5e-09 38.1 0.1 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme IQ PF00612.27 KXG49557.1 - 0.005 16.5 1.4 0.016 14.9 1.4 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif 2OG-FeII_Oxy_3 PF13640.6 KXG49558.1 - 2.5e-09 37.9 0.0 4.4e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.24 KXG49559.1 - 6.6e-94 315.3 26.4 7.5e-94 315.1 26.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG49559.1 - 1.6e-26 93.1 27.8 1.6e-26 93.1 27.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG49559.1 - 1.4e-05 23.7 1.7 1.4e-05 23.7 1.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ATP1G1_PLM_MAT8 PF02038.16 KXG49560.1 - 0.11 11.9 1.7 23 4.5 0.0 3.6 4 0 0 4 4 4 0 ATP1G1/PLM/MAT8 family Fungal_trans_2 PF11951.8 KXG49561.1 - 0.00072 18.5 0.0 0.0054 15.6 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG49561.1 - 0.0019 18.3 1.6 0.0035 17.4 1.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WHH PF14414.6 KXG49561.1 - 0.016 15.0 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH Ribonuclease_3 PF00636.26 KXG49562.1 - 0.095 13.3 0.0 0.12 13.0 0.0 1.5 1 1 0 1 1 1 0 Ribonuclease III domain Cauli_VI PF01693.16 KXG49563.1 - 3.5e-10 40.0 1.1 5.7e-10 39.3 0.4 1.8 2 0 0 2 2 2 1 Caulimovirus viroplasmin SinI PF08671.10 KXG49563.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Anti-repressor SinI GlyL_C PF12524.8 KXG49563.1 - 0.098 12.8 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 dsDNA virus glycoprotein L C terminal CVNH PF08881.10 KXG49564.1 - 8.9e-29 100.2 0.3 9.8e-29 100.0 0.3 1.0 1 0 0 1 1 1 1 CVNH domain MCM PF00493.23 KXG49565.1 - 2.8e-104 347.1 0.1 6.2e-104 346.0 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KXG49565.1 - 2.4e-36 124.4 0.5 5e-36 123.3 0.5 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXG49565.1 - 2.4e-29 101.6 2.1 6e-29 100.3 2.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXG49565.1 - 5.2e-15 55.9 0.2 1.3e-14 54.6 0.2 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXG49565.1 - 3.1e-06 26.7 0.0 0.00079 18.9 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXG49565.1 - 2.1e-05 24.5 0.0 4.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXG49565.1 - 0.00056 19.8 0.0 0.0019 18.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXG49565.1 - 0.063 13.0 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 KXG49565.1 - 0.1 13.0 0.1 0.37 11.2 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Imm35 PF15567.6 KXG49565.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 35 Mg_chelatase_C PF13335.6 KXG49565.1 - 0.15 12.8 1.0 0.35 11.5 0.4 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal Vps54 PF07928.12 KXG49566.1 - 3e-50 170.1 0.1 1.4e-49 167.9 0.1 2.3 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 KXG49566.1 - 6.9e-07 28.8 0.4 1.9e-06 27.4 0.4 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KXG49566.1 - 4.8e-05 23.3 0.1 0.00012 21.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Autophagy_N PF03986.13 KXG49568.1 - 0.036 14.0 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain Glycogen_syn PF05693.13 KXG49569.1 - 0 1150.8 0.0 0 1150.6 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_trans_1_4 PF13692.6 KXG49569.1 - 9.8e-06 26.0 0.0 0.015 15.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KXG49569.1 - 2.1e-05 24.1 0.0 0.0022 17.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KXG49569.1 - 3.9e-05 23.5 0.1 9.3e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 KXG49569.1 - 4.3e-05 23.6 0.6 9.9e-05 22.4 0.6 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KXG49569.1 - 0.0008 19.9 0.1 0.0018 18.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain NMT1 PF09084.11 KXG49570.1 - 6.6e-79 264.8 0.0 8.3e-79 264.5 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KXG49570.1 - 0.00025 20.8 0.5 0.12 12.0 0.0 3.1 3 1 0 3 3 3 2 NMT1-like family COG2 PF06148.11 KXG49572.1 - 7.3e-37 126.4 1.6 1e-36 126.0 1.6 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 KXG49572.1 - 8.1e-06 25.8 0.5 4e-05 23.6 0.2 2.2 1 1 1 2 2 2 1 Vps51/Vps67 COG5 PF10392.9 KXG49572.1 - 0.00074 19.7 0.2 0.0046 17.1 0.1 2.0 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF2046 PF09755.9 KXG49572.1 - 0.015 14.5 2.7 0.023 13.9 2.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Vps54_N PF10475.9 KXG49572.1 - 0.053 12.8 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Bul1_C PF04426.12 KXG49572.1 - 0.1 12.0 0.0 0.25 10.7 0.0 1.6 1 1 0 1 1 1 0 Bul1 C terminus DivIVA PF05103.13 KXG49572.1 - 0.11 12.6 1.8 0.25 11.4 0.4 2.0 1 1 1 2 2 2 0 DivIVA protein Neuregulin PF02158.15 KXG49572.1 - 0.16 11.3 0.4 2.2 7.6 0.5 2.0 1 1 0 2 2 2 0 Neuregulin intracellular region Bcr-Abl_Oligo PF09036.10 KXG49572.1 - 0.16 12.0 0.4 0.55 10.3 0.0 2.0 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Vir_act_alpha_C PF10400.9 KXG49572.1 - 0.25 12.1 5.0 7.3 7.4 2.6 2.6 2 1 1 3 3 3 0 Virulence activator alpha C-term SKA2 PF16740.5 KXG49572.1 - 0.25 11.1 2.5 0.98 9.2 0.4 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Spc7 PF08317.11 KXG49572.1 - 0.43 9.4 3.0 0.65 8.8 3.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein IFT57 PF10498.9 KXG49572.1 - 0.59 9.0 5.7 0.096 11.6 0.3 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Ribosomal_L1 PF00687.21 KXG49573.1 - 2.6e-28 99.2 0.0 3e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.21 KXG49574.1 - 4.3e-104 347.8 0.0 5.9e-104 347.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KXG49574.1 - 1.6e-36 125.8 0.1 2.7e-36 125.0 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KXG49574.1 - 0.027 13.8 0.3 0.066 12.5 0.2 1.5 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain E1-E2_ATPase PF00122.20 KXG49575.1 - 2.5e-34 118.3 7.2 4.4e-22 78.5 1.0 3.6 3 0 0 3 3 3 3 E1-E2 ATPase Hydrolase PF00702.26 KXG49575.1 - 1.3e-17 64.8 0.0 3.7e-17 63.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXG49575.1 - 3.7e-09 36.1 0.0 7.5e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXG49575.1 - 0.004 16.9 0.0 0.022 14.5 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FixP_N PF14715.6 KXG49575.1 - 2.9 7.7 5.8 24 4.7 0.7 2.8 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Glyco_hydro_18 PF00704.28 KXG49576.1 - 4.9e-25 88.9 4.1 2e-24 86.9 4.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Cation_ATPase_C PF00689.21 KXG49577.1 - 8.5e-50 169.0 9.2 2.1e-49 167.7 9.2 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXG49577.1 - 4.6e-33 114.3 0.1 4.6e-33 114.3 0.1 3.2 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXG49577.1 - 1.6e-23 82.6 0.0 2.9e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXG49577.1 - 4.1e-19 69.7 0.0 1e-18 68.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXG49577.1 - 3.4e-11 42.7 0.2 1.2e-09 37.7 0.1 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXG49577.1 - 5.4e-05 23.0 0.1 0.011 15.5 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Ferlin_C PF16165.5 KXG49577.1 - 0.016 15.2 0.1 0.042 13.8 0.1 1.6 1 0 0 1 1 1 0 Ferlin C-terminus NMT1 PF09084.11 KXG49578.1 - 0.00014 21.8 0.0 0.00067 19.7 0.0 1.9 1 1 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 KXG49578.1 - 0.00056 19.6 0.0 0.004 16.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 KXG49578.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 NMT1-like family SBP_bac_3 PF00497.20 KXG49578.1 - 0.089 12.2 0.0 3.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 PQ-loop PF04193.14 KXG49579.1 - 8e-21 73.6 3.7 5.2e-13 48.6 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat LMBR1 PF04791.16 KXG49579.1 - 0.0039 16.2 0.0 0.0081 15.1 0.0 1.4 1 1 0 1 1 1 1 LMBR1-like membrane protein ER_lumen_recept PF00810.18 KXG49579.1 - 0.02 15.7 3.5 0.067 14.0 2.9 1.9 1 1 0 1 1 1 0 ER lumen protein retaining receptor DUF4679 PF15728.5 KXG49579.1 - 0.077 12.0 9.7 0.11 11.6 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) Phage_holin_5_2 PF16079.5 KXG49579.1 - 0.15 12.4 0.1 0.15 12.4 0.1 2.7 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V CENP-H PF05837.12 KXG49580.1 - 0.0051 17.2 0.1 0.0051 17.2 0.1 2.3 2 0 0 2 2 2 1 Centromere protein H (CENP-H) DUF16 PF01519.16 KXG49580.1 - 0.022 15.2 9.3 0.036 14.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 RasGAP PF00616.19 KXG49580.1 - 0.078 12.7 0.0 0.3 10.8 0.0 1.8 1 1 1 2 2 2 0 GTPase-activator protein for Ras-like GTPase HSP20 PF00011.21 KXG49580.1 - 0.43 10.7 3.9 0.37 11.0 0.3 2.3 2 0 0 2 2 2 0 Hsp20/alpha crystallin family NDUF_B4 PF07225.12 KXG49580.1 - 0.54 10.2 3.4 2.5 8.0 0.1 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Abhydrolase_3 PF07859.13 KXG49582.1 - 1.8e-48 165.2 0.1 2.6e-48 164.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXG49582.1 - 3.2e-08 32.9 0.0 7.4e-08 31.7 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 KXG49582.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXG49582.1 - 0.02 14.3 0.0 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXG49582.1 - 0.081 12.2 0.1 0.77 9.0 0.0 2.4 2 1 1 3 3 3 0 Serine aminopeptidase, S33 DLH PF01738.18 KXG49582.1 - 0.097 12.2 0.3 0.31 10.6 0.0 2.0 3 0 0 3 3 3 0 Dienelactone hydrolase family GST_C_3 PF14497.6 KXG49583.1 - 2.6e-12 46.8 0.0 4.7e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXG49583.1 - 4.9e-12 46.1 0.0 8.5e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXG49583.1 - 1.9e-11 44.0 0.0 3.4e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXG49583.1 - 2.7e-11 43.6 0.0 5.6e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXG49583.1 - 4.3e-09 36.5 0.0 8.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXG49583.1 - 3.6e-07 30.1 0.1 8.3e-07 28.9 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_C7 PF01830.18 KXG49583.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase C7 family MFS_1 PF07690.16 KXG49584.1 - 9.8e-36 123.4 33.1 9.8e-36 123.4 33.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily SpoVAB PF13782.6 KXG49584.1 - 0.011 16.0 1.2 0.011 16.0 1.2 2.3 3 0 0 3 3 3 0 Stage V sporulation protein AB Glyco_hydro_31 PF01055.26 KXG49585.1 - 1.1e-136 456.5 8.3 1.5e-136 456.1 8.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXG49585.1 - 9.9e-26 89.9 0.4 6.6e-24 84.0 0.1 2.9 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KXG49585.1 - 9.7e-08 32.2 0.8 3.2e-07 30.5 0.8 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) NDK PF00334.19 KXG49586.1 - 1.1e-53 180.8 0.0 1.3e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.9 KXG49587.1 - 1.7e-30 105.2 0.0 3.2e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KXG49587.1 - 0.0023 18.4 0.0 0.0028 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) MTHFR PF02219.17 KXG49588.1 - 2.7e-96 322.3 0.0 3.8e-96 321.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TGT PF01702.18 KXG49589.1 - 3.9e-65 220.3 0.0 4.9e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylate_kin PF02223.17 KXG49590.1 - 2.5e-48 164.2 0.0 2.8e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 KXG49590.1 - 0.00049 19.6 0.1 0.0019 17.7 0.0 1.8 2 1 0 2 2 2 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KXG49590.1 - 0.027 13.7 0.1 2.2 7.5 0.0 2.3 2 1 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 KXG49590.1 - 0.045 14.3 0.0 0.18 12.4 0.0 1.8 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXG49590.1 - 0.096 13.1 0.1 0.22 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain GIY-YIG PF01541.24 KXG49591.1 - 5.9e-13 48.9 0.0 1.7e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain PLU-1 PF08429.11 KXG49592.1 - 3.2e-110 368.5 16.2 4e-106 355.0 15.0 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 KXG49592.1 - 4.5e-43 146.3 0.1 1.2e-42 145.0 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 KXG49592.1 - 2.2e-21 76.3 0.0 5.8e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 KXG49592.1 - 2.4e-17 62.6 29.9 2.6e-09 36.8 7.8 3.6 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.17 KXG49592.1 - 2.7e-17 62.4 3.5 7e-17 61.1 2.5 2.3 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.16 KXG49592.1 - 3.5e-13 49.7 8.8 1.1e-12 48.1 8.8 2.0 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.6 KXG49592.1 - 0.00021 21.0 1.7 0.00021 21.0 1.7 3.0 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 KXG49592.1 - 0.0025 17.3 2.4 0.0025 17.3 2.4 2.7 3 0 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.6 KXG49592.1 - 0.0053 16.7 2.5 0.0053 16.7 2.5 3.2 2 1 1 3 3 3 1 Prokaryotic RING finger family 1 PHD_4 PF16866.5 KXG49592.1 - 1.5 9.0 19.2 1.2 9.3 5.1 3.0 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 KXG49592.1 - 8.1 6.4 25.3 0.18 11.7 0.5 3.6 3 0 0 3 3 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PALP PF00291.25 KXG49593.1 - 8.4e-34 117.3 0.0 1e-33 117.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HEV_ORF1 PF02444.16 KXG49593.1 - 0.064 13.8 1.4 0.13 12.8 1.4 1.5 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) DHHA2 PF02833.14 KXG49594.1 - 2.6e-30 105.5 0.7 1e-29 103.6 0.0 2.1 3 0 0 3 3 3 1 DHHA2 domain DHH PF01368.20 KXG49594.1 - 1e-06 28.9 0.0 2.3e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 DHH family Transglut_core PF01841.19 KXG49595.1 - 3.7e-08 33.8 0.0 8.1e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 KXG49595.1 - 7.4e-08 32.0 0.1 2.1e-07 30.5 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXG49595.1 - 5.9e-06 25.8 0.4 1.9e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXG49595.1 - 0.014 15.2 2.3 0.021 14.7 0.2 2.4 3 0 0 3 3 3 0 Variant SH3 domain Cu-oxidase_3 PF07732.15 KXG49596.1 - 3.5e-41 139.9 5.5 2.3e-40 137.3 1.0 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXG49596.1 - 1.5e-25 89.6 13.8 2.7e-22 79.0 0.3 3.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KXG49596.1 - 2e-21 76.8 0.0 1.1e-19 71.1 0.0 2.6 2 1 0 2 2 2 1 Multicopper oxidase SAT PF16073.5 KXG49597.1 - 1.6e-85 286.7 0.6 6.1e-84 281.5 0.0 2.7 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 KXG49597.1 - 8.3e-80 268.0 0.0 1.4e-79 267.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXG49597.1 - 1.9e-43 149.2 0.1 4e-43 148.1 0.1 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXG49597.1 - 1.5e-33 115.3 0.1 3.5e-33 114.1 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KXG49597.1 - 1.5e-23 82.9 5.7 1.9e-11 44.1 1.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 KXG49597.1 - 2.7e-20 73.5 0.1 2.4e-19 70.4 0.0 2.8 3 1 0 3 3 3 1 Thioesterase domain PS-DH PF14765.6 KXG49597.1 - 8.4e-12 44.9 0.0 1.5e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.7 KXG49597.1 - 5.3e-05 23.9 0.2 0.0015 19.1 0.1 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 KXG49597.1 - 0.00017 21.0 0.0 0.00063 19.2 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KXG49597.1 - 0.0004 20.8 0.0 0.0014 19.0 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension HDA2-3 PF11496.8 KXG49598.1 - 6.9e-50 169.9 0.0 2e-48 165.1 0.0 2.4 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 UBA2_C PF16195.5 KXG49598.1 - 0.047 14.4 0.6 0.047 14.4 0.6 3.8 3 0 0 3 3 3 0 SUMO-activating enzyme subunit 2 C-terminus TMEM192 PF14802.6 KXG49598.1 - 0.4 9.8 4.5 0.32 10.0 1.2 2.1 2 0 0 2 2 2 0 TMEM192 family SirA PF10747.9 KXG49598.1 - 1.5 9.1 3.3 18 5.6 0.0 2.7 2 0 0 2 2 2 0 Sporulation inhibitor of replication protein SirA FMO-like PF00743.19 KXG49599.1 - 2e-45 155.2 0.0 2.6e-26 92.1 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXG49599.1 - 1.2e-14 54.3 0.0 3.3e-12 46.3 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG49599.1 - 2.1e-11 43.5 0.1 2.1e-08 33.7 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXG49599.1 - 2.7e-10 40.0 0.0 6.2e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG49599.1 - 4.1e-10 39.9 0.0 1.8e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KXG49599.1 - 9e-08 32.1 0.0 0.14 11.7 0.0 3.2 2 1 1 3 3 3 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG49599.1 - 5.6e-06 26.5 0.2 4.6e-05 23.6 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXG49599.1 - 1.3e-05 24.6 0.1 0.00086 18.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KXG49599.1 - 0.0064 17.0 0.3 5.3 7.7 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXG49599.1 - 0.012 14.4 0.1 0.77 8.4 0.0 2.7 3 0 0 3 3 3 0 HI0933-like protein GyrB_insert PF18053.1 KXG49599.1 - 0.11 12.4 0.1 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain POT1 PF02765.17 KXG49600.1 - 3.3e-15 56.2 0.0 5.7e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 NUDIX-like PF09296.11 KXG49604.1 - 2.9e-20 72.8 0.0 8e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.28 KXG49604.1 - 1.4e-17 64.0 0.1 2.8e-17 63.0 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 KXG49604.1 - 6.6e-06 25.7 1.7 1.5e-05 24.5 1.7 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain CN_hydrolase PF00795.22 KXG49605.1 - 4.8e-44 150.7 0.0 6.3e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KXG49605.1 - 1.3e-22 80.1 0.0 6.4e-22 77.9 0.0 2.0 1 1 0 1 1 1 1 NAD synthase APG6_N PF17675.1 KXG49606.1 - 2.9 8.4 7.8 2.3 8.8 6.0 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region Questin_oxidase PF14027.6 KXG49607.1 - 7e-86 288.8 0.0 9e-86 288.5 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like ERCC3_RAD25_C PF16203.5 KXG49608.1 - 2.5e-124 413.4 2.0 4.4e-124 412.6 2.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KXG49608.1 - 3.1e-36 124.3 0.0 8.6e-36 122.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG49608.1 - 5e-16 59.2 0.0 9.6e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXG49608.1 - 1.8e-13 50.8 0.1 4.1e-13 49.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KXG49608.1 - 1.1e-09 37.5 0.0 1.4e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KXG49608.1 - 0.00066 19.5 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KXG49608.1 - 0.0014 17.6 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF4748 PF15932.5 KXG49609.1 - 1.1e-22 79.5 1.8 1.3e-22 79.2 1.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4748) FAM165 PF14981.6 KXG49609.1 - 0.97 9.3 3.8 2.1 8.2 0.2 2.2 1 1 1 2 2 2 0 FAM165 family CTD_bind PF04818.13 KXG49610.1 - 1e-07 32.7 0.1 2.4e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. EBA-175_VI PF11556.8 KXG49611.1 - 0.49 10.8 5.0 0.58 10.5 1.4 2.1 2 0 0 2 2 2 0 Erythrocyte binding antigen 175 MFS_1 PF07690.16 KXG49612.1 - 1e-39 136.5 37.7 9.1e-35 120.2 24.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2615 PF11027.8 KXG49612.1 - 0.027 14.6 0.1 0.06 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) OATP PF03137.20 KXG49612.1 - 5.1 5.3 11.4 1.3 7.2 0.1 3.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Lactonase PF10282.9 KXG49613.1 - 9e-72 242.2 0.0 1.1e-71 241.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NHL PF01436.21 KXG49613.1 - 0.014 15.4 0.5 0.67 10.1 0.2 2.6 2 0 0 2 2 2 0 NHL repeat GMC_oxred_N PF00732.19 KXG49614.1 - 1.9e-73 247.5 0.0 2.4e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG49614.1 - 2.7e-23 83.1 0.0 4.9e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXG49614.1 - 0.00056 20.1 0.1 0.0013 18.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXG49614.1 - 0.0011 18.1 0.0 0.0022 17.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXG49614.1 - 0.0011 18.6 0.0 0.0046 16.6 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXG49614.1 - 0.002 17.4 0.1 0.0037 16.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KXG49614.1 - 0.029 13.4 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXG49614.1 - 0.041 13.1 0.1 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldose_epim PF01263.20 KXG49615.1 - 1.2e-47 162.7 0.2 1.8e-47 162.1 0.2 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Arm-DNA-bind_2 PF12167.8 KXG49615.1 - 0.017 15.0 0.0 0.065 13.2 0.0 1.8 2 0 0 2 2 2 0 Arm DNA-binding domain Ank_4 PF13637.6 KXG49616.1 - 1.9e-89 293.0 0.5 4.5e-10 39.8 0.0 8.5 1 1 8 10 10 10 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXG49616.1 - 5.8e-75 247.9 0.1 3.1e-14 53.3 0.0 6.2 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG49616.1 - 6.9e-57 182.7 0.0 0.0048 17.3 0.0 11.9 12 0 0 12 12 12 11 Ankyrin repeat Ank PF00023.30 KXG49616.1 - 7.4e-50 165.3 0.0 0.00028 21.2 0.0 11.6 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 KXG49616.1 - 2.1e-34 117.2 0.0 8.7e-06 25.9 0.0 8.0 3 3 6 10 10 10 9 Ankyrin repeats (many copies) DUF1204 PF06721.11 KXG49616.1 - 3.8e-06 26.5 10.1 5.9 6.3 0.1 7.4 1 1 7 8 8 8 3 Protein of unknown function (DUF1204) PEGA PF08308.11 KXG49616.1 - 1e-05 25.3 0.2 4.1 7.4 0.0 6.3 5 2 2 7 7 7 1 PEGA domain UXS1_N PF11803.8 KXG49616.1 - 0.00013 22.3 0.2 73 3.8 0.0 5.9 4 2 2 6 6 6 0 UDP-glucuronate decarboxylase N-terminal Phage_GP20 PF06810.11 KXG49616.1 - 0.00024 20.9 6.0 16 5.2 0.0 6.4 8 0 0 8 8 8 0 Phage minor structural protein GP20 P_C PF06640.11 KXG49616.1 - 0.00033 20.9 6.8 8.3 6.5 0.0 5.8 3 3 4 7 7 7 1 P protein C-terminus DUF5308 PF17233.2 KXG49616.1 - 0.00093 19.5 0.2 8.1 6.6 0.0 3.5 4 0 0 4 4 3 1 Family of unknown function (DUF5308) Cthe_2159 PF14262.6 KXG49616.1 - 0.0016 17.8 0.8 1.8 7.8 0.6 3.9 1 1 0 2 2 2 1 Carbohydrate-binding domain-containing protein Cthe_2159 DoxD PF04173.13 KXG49616.1 - 0.13 12.1 0.0 10 6.0 0.0 3.7 4 2 1 5 5 5 0 TQO small subunit DoxD Cyclophil_like2 PF18050.1 KXG49616.1 - 0.16 11.9 0.0 1e+02 2.9 0.0 4.1 5 1 0 5 5 5 0 Cyclophilin-like family VWA_3_C PF18571.1 KXG49616.1 - 0.4 10.6 25.7 6.9 6.6 0.1 8.3 10 0 0 10 10 10 0 von Willebrand factor type A C-terminal domain DUF348 PF03990.14 KXG49616.1 - 4.3 7.2 7.9 15 5.5 0.1 4.0 4 0 0 4 4 4 0 G5-linked-Ubiquitin-like domain p450 PF00067.22 KXG49617.1 - 7.3e-41 140.4 0.0 1e-40 139.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GatB_Yqey PF02637.18 KXG49617.1 - 0.087 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 GatB domain Fungal_trans PF04082.18 KXG49618.1 - 5.9e-13 48.5 0.1 1.7e-12 47.0 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG49618.1 - 0.00044 20.3 4.9 0.00076 19.5 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GP4 PF03010.14 KXG49618.1 - 0.44 10.4 0.1 0.44 10.4 0.1 1.7 2 0 0 2 2 2 0 GP4 Trp_DMAT PF11991.8 KXG49619.1 - 2.9e-114 382.3 0.0 3.3e-114 382.1 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase AMP-binding PF00501.28 KXG49620.1 - 1.6e-128 429.0 0.0 5.3e-72 242.7 0.0 3.3 2 1 1 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KXG49620.1 - 2.6e-73 247.3 0.0 3.9e-45 154.4 0.0 2.2 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KXG49620.1 - 1.9e-23 82.6 0.3 1.1e-06 28.9 0.0 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXG49620.1 - 3.1e-15 56.9 0.2 5.3e-06 27.3 0.1 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 KXG49620.1 - 0.082 12.7 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain CCDC24 PF15669.5 KXG49621.1 - 0.3 10.9 2.4 0.31 10.9 2.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family EMP24_GP25L PF01105.24 KXG49622.1 - 1.9e-47 161.6 4.1 2.1e-47 161.4 4.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD USP7_ICP0_bdg PF12436.8 KXG49623.1 - 3.2e-87 291.8 3.7 4.7e-87 291.3 1.8 2.1 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KXG49623.1 - 9.1e-74 247.6 1.6 3.1e-70 236.1 0.0 3.0 2 1 1 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KXG49623.1 - 1.9e-50 171.8 0.9 1.9e-50 171.8 0.9 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXG49623.1 - 6e-22 78.6 0.0 1.3e-21 77.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KXG49623.1 - 5.2e-07 29.8 0.0 1.8e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 MATH domain Rad60-SLD PF11976.8 KXG49623.1 - 0.038 13.8 2.7 2.2 8.2 0.1 4.4 4 1 0 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 KXG49623.1 - 0.11 13.2 0.0 19 6.0 0.0 2.8 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD Peptidase_C98 PF15499.6 KXG49623.1 - 0.63 9.5 4.0 0.32 10.4 0.2 2.3 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase BCDHK_Adom3 PF10436.9 KXG49624.1 - 5.8e-44 149.8 0.3 1.7e-43 148.3 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXG49624.1 - 4.6e-06 27.1 0.0 1.8e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXG49624.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pmp3 PF01679.17 KXG49625.1 - 1.4e-21 76.4 10.8 1.8e-21 76.1 10.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator NapE PF06796.11 KXG49625.1 - 0.38 10.3 3.4 0.51 9.9 3.4 1.2 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE SPC22 PF04573.12 KXG49626.1 - 4.8e-39 133.6 0.4 4.7e-28 97.8 0.2 2.2 2 0 0 2 2 2 2 Signal peptidase subunit GGACT PF06094.12 KXG49627.1 - 3.1e-17 63.3 0.1 5.1e-16 59.4 0.1 2.0 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Peptidase_C48 PF02902.19 KXG49628.1 - 3.1e-33 115.5 0.0 9.8e-33 113.8 0.0 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain IF4E PF01652.18 KXG49629.1 - 1.9e-54 183.7 0.0 3.2e-54 183.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.25 KXG49630.1 - 1.1e-69 234.8 0.0 1.4e-69 234.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG49630.1 - 4.1e-34 118.0 0.0 8.6e-34 117.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG49630.1 - 0.0001 21.7 0.0 0.0049 16.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXG49630.1 - 0.051 12.9 0.3 0.12 11.7 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXG49630.1 - 0.056 12.2 0.0 0.056 12.2 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 KXG49630.1 - 0.17 10.8 0.1 1.1 8.1 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain GTP_cyclohydroI PF01227.22 KXG49633.1 - 4.2e-73 244.6 0.7 5.5e-73 244.2 0.7 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KXG49633.1 - 0.012 15.7 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 QueF-like protein CAF1C_H4-bd PF12265.8 KXG49634.1 - 4.6e-29 100.5 0.7 2.4e-28 98.2 0.8 2.3 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KXG49634.1 - 3.3e-26 91.0 12.6 3.4e-06 27.7 0.2 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG49634.1 - 6.3e-06 26.4 0.6 0.21 11.9 0.0 4.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3751 PF12571.8 KXG49634.1 - 0.0096 16.0 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 2 Phage tail-collar fibre protein XRN_M PF17846.1 KXG49635.1 - 2.6e-100 336.4 4.0 4.1e-100 335.8 4.0 1.2 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KXG49635.1 - 6.8e-97 323.6 0.0 1.4e-96 322.6 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KXG49635.1 - 7.3e-74 247.7 0.1 2.4e-73 246.0 0.0 1.9 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KXG49635.1 - 1.1e-32 112.0 0.0 3e-32 110.7 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KXG49635.1 - 5.6e-24 84.0 0.3 1.2e-23 83.0 0.3 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KXG49635.1 - 2.2e-06 27.7 0.1 7.2e-06 26.0 0.1 2.0 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 SLBP_RNA_bind PF15247.6 KXG49635.1 - 0.29 11.3 1.5 0.43 10.7 0.3 1.9 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain WD40 PF00400.32 KXG49636.1 - 9.4e-39 130.7 21.1 3.2e-09 37.3 0.5 12.3 13 0 0 13 13 13 6 WD domain, G-beta repeat p450 PF00067.22 KXG49636.1 - 3.9e-31 108.3 0.0 7.6e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Utp12 PF04003.12 KXG49636.1 - 8.7e-28 96.8 0.0 1.9e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KXG49636.1 - 4.4e-24 84.6 0.0 0.00072 19.8 0.0 10.3 6 2 6 12 12 12 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXG49636.1 - 9.2e-09 34.7 0.4 0.13 11.2 0.0 4.5 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXG49636.1 - 5.2e-07 29.7 2.7 0.03 14.2 0.1 6.0 6 1 1 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXG49636.1 - 1.1e-05 24.4 4.5 0.37 9.4 0.0 5.2 2 2 2 5 5 5 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KXG49636.1 - 0.0026 18.2 0.6 8.3 7.0 0.1 4.9 5 0 0 5 5 5 1 PQQ-like domain WD40_like PF17005.5 KXG49636.1 - 0.0038 16.6 0.0 0.65 9.3 0.0 3.3 4 1 1 5 5 5 1 WD40-like domain Nbas_N PF15492.6 KXG49636.1 - 0.015 14.6 0.3 6.5 6.0 0.0 3.3 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.11 KXG49636.1 - 0.084 11.9 0.4 2.7 7.0 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) PD40 PF07676.12 KXG49636.1 - 0.1 12.6 0.1 20 5.3 0.0 4.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Septin PF00735.18 KXG49637.1 - 1.6e-112 375.4 0.3 2.3e-112 374.9 0.3 1.2 1 0 0 1 1 1 1 Septin WD40 PF00400.32 KXG49637.1 - 3.7e-15 56.0 9.2 0.00016 22.4 0.5 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG49637.1 - 4.6e-08 33.3 0.4 0.18 12.1 0.0 4.8 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain MMR_HSR1 PF01926.23 KXG49637.1 - 6.2e-07 29.5 0.0 1.5e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXG49637.1 - 1.2e-05 25.3 0.0 9.6e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KXG49637.1 - 3.4e-05 23.5 4.4 0.00011 21.9 0.3 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KXG49637.1 - 0.002 18.4 0.0 0.0061 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain PQQ PF01011.21 KXG49637.1 - 0.003 17.4 0.2 2 8.5 0.1 2.7 2 0 0 2 2 2 1 PQQ enzyme repeat Pox_A32 PF04665.12 KXG49637.1 - 0.0066 15.9 0.1 0.012 15.1 0.1 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein FLgD_tudor PF13861.6 KXG49637.1 - 0.0093 16.2 0.7 2.6 8.3 0.0 3.1 2 1 1 3 3 3 1 FlgD Tudor-like domain Roc PF08477.13 KXG49637.1 - 0.0097 16.1 0.3 0.035 14.3 0.1 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KXG49637.1 - 0.023 14.0 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 AIG1 family AAA_24 PF13479.6 KXG49637.1 - 0.025 14.3 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain FOXP-CC PF16159.5 KXG49637.1 - 0.026 15.1 1.0 0.074 13.7 1.0 1.7 1 0 0 1 1 1 0 FOXP coiled-coil domain IIGP PF05049.13 KXG49637.1 - 0.026 13.6 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Glyco_hydro_8 PF01270.17 KXG49637.1 - 0.052 12.4 0.1 0.11 11.3 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 Casc1_N PF15927.5 KXG49637.1 - 0.067 12.9 5.1 0.16 11.7 5.1 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus AAA_16 PF13191.6 KXG49637.1 - 0.074 13.4 0.0 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Ras PF00071.22 KXG49637.1 - 0.085 12.5 0.1 0.29 10.7 0.1 1.9 1 0 0 1 1 1 0 Ras family NACHT PF05729.12 KXG49637.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KXG49637.1 - 0.17 12.4 0.1 0.54 10.8 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 KXG49637.1 - 0.83 9.7 3.5 15 5.6 0.1 2.9 2 1 1 3 3 3 0 Dynamin family ACT_7 PF13840.6 KXG49638.1 - 6.3e-26 89.9 0.2 2.1e-17 62.6 0.0 3.3 3 0 0 3 3 3 3 ACT domain Chorion_3 PF05387.11 KXG49638.1 - 0.17 11.5 0.0 0.38 10.4 0.1 1.5 2 0 0 2 2 2 0 Chorion family 3 Cu-oxidase_3 PF07732.15 KXG49639.1 - 2e-42 144.0 9.3 6.5e-42 142.3 1.5 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXG49639.1 - 1.2e-38 131.9 1.7 1.2e-38 131.9 1.7 4.0 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 KXG49639.1 - 4.9e-36 124.2 2.1 1.2e-34 119.7 0.2 2.8 3 0 0 3 3 3 1 Multicopper oxidase COX4_pro_2 PF07835.12 KXG49640.1 - 0.0021 18.1 0.1 0.0044 17.1 0.1 1.5 1 0 0 1 1 1 1 Bacterial aa3 type cytochrome c oxidase subunit IV BNR PF02012.20 KXG49641.1 - 0.098 12.7 0.2 0.34 11.1 0.2 2.0 1 0 0 1 1 1 0 BNR/Asp-box repeat Scytalone_dh PF02982.14 KXG49642.1 - 1.2e-79 265.7 3.9 1.5e-79 265.4 3.9 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KXG49642.1 - 7.8e-08 32.5 1.9 9.5e-08 32.2 1.9 1.1 1 0 0 1 1 1 1 SnoaL-like domain adh_short_C2 PF13561.6 KXG49643.1 - 3.7e-55 187.0 0.4 6.4e-55 186.3 0.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG49643.1 - 7.9e-47 159.2 1.2 9.9e-47 158.9 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG49643.1 - 6.7e-16 58.7 0.9 8.9e-16 58.3 0.9 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KXG49643.1 - 0.0082 15.5 0.1 0.22 10.8 0.1 2.1 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KXG49643.1 - 0.026 14.0 0.7 0.039 13.4 0.7 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CABS1 PF15367.6 KXG49643.1 - 0.23 10.5 0.0 0.3 10.2 0.0 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 DUF1100 PF06500.11 KXG49644.1 - 1.6e-13 50.2 0.0 2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.18 KXG49644.1 - 2.2e-07 30.7 0.0 3.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KXG49644.1 - 2.2e-06 27.3 0.0 4.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KXG49644.1 - 0.0002 21.4 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 KXG49644.1 - 0.00035 20.3 0.0 0.0012 18.6 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 KXG49644.1 - 0.0028 18.3 2.2 0.0033 18.1 1.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG49644.1 - 0.018 14.3 0.0 0.07 12.4 0.0 1.9 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXG49644.1 - 0.12 12.0 0.0 0.33 10.6 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold NAAA-beta PF15508.6 KXG49645.1 - 2.5e-15 56.5 0.2 4.3e-15 55.7 0.2 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Zwint PF15556.6 KXG49645.1 - 0.077 12.5 0.8 0.12 11.8 0.8 1.2 1 0 0 1 1 1 0 ZW10 interactor Fungal_trans PF04082.18 KXG49646.1 - 1.9e-14 53.3 1.7 3.3e-14 52.6 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG49646.1 - 5.9e-06 26.3 9.9 1.5e-05 25.0 9.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L4 PF00573.22 KXG49647.1 - 4.7e-39 134.1 0.3 6.8e-39 133.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KXG49647.1 - 1.4e-30 105.2 1.6 1.4e-30 105.2 1.6 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Glyco_hydro_61 PF03443.14 KXG49648.1 - 0.003 17.5 0.0 0.0063 16.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 KXG49648.1 - 0.0065 17.1 1.1 0.026 15.2 0.0 2.1 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading TFIIF_alpha PF05793.12 KXG49648.1 - 3.7 6.0 4.9 4.5 5.7 4.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SOG2 PF10428.9 KXG49648.1 - 7.1 5.7 10.0 8.7 5.4 10.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein UPF0029 PF01205.19 KXG49649.1 - 2.3e-34 117.9 0.1 3.8e-34 117.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KXG49649.1 - 1.3e-07 31.9 0.0 1.7e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain LCCL PF03815.19 KXG49650.1 - 9e-25 86.6 0.1 1.4e-24 86.0 0.1 1.3 1 0 0 1 1 1 1 LCCL domain AhpC-TSA_2 PF13911.6 KXG49651.1 - 1.6e-11 44.3 0.0 3.5e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Zn_clus PF00172.18 KXG49651.1 - 5.1e-05 23.3 3.2 9.7e-05 22.4 3.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.6 KXG49652.1 - 8.6e-32 109.3 9.0 2.6e-10 40.4 0.1 6.7 3 1 4 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.6 KXG49652.1 - 9.4e-27 92.1 4.5 0.00015 21.6 0.0 8.4 8 1 0 8 8 8 6 Tetratricopeptide repeat TPR_MalT PF17874.1 KXG49652.1 - 1.4e-06 27.9 2.6 3.5e-06 26.6 0.7 2.6 3 1 0 3 3 3 1 MalT-like TPR region NB-ARC PF00931.22 KXG49652.1 - 2.4e-06 27.0 0.0 9.3e-06 25.0 0.0 2.1 2 1 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 KXG49652.1 - 7e-05 23.3 0.0 0.00042 20.7 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain TPR_8 PF13181.6 KXG49652.1 - 0.00013 21.9 0.1 16 6.0 0.0 4.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXG49652.1 - 0.00054 20.6 1.3 66 4.7 0.0 6.3 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXG49652.1 - 0.0015 18.3 0.9 2.3 8.2 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXG49652.1 - 0.0047 17.4 2.4 6.9 7.3 0.0 4.8 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXG49652.1 - 0.03 15.0 0.0 0.99 10.1 0.0 2.9 1 1 0 1 1 1 0 Tetratricopeptide repeat ATPase_2 PF01637.18 KXG49652.1 - 0.078 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Porphobil_deam PF01379.20 KXG49653.1 - 2.7e-62 209.9 0.0 3.6e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KXG49653.1 - 2.8e-13 50.0 0.1 5.8e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Epimerase PF01370.21 KXG49654.1 - 0.022 14.2 0.0 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AA_permease PF00324.21 KXG49655.1 - 9.7e-21 73.9 10.8 1.1e-20 73.7 10.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG49656.1 - 1.1e-80 271.6 32.5 1.2e-80 271.4 32.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG49656.1 - 5e-23 81.6 32.7 5.6e-23 81.5 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 KXG49656.1 - 0.5 11.1 0.0 0.5 11.1 0.0 3.3 4 1 0 4 4 4 0 PrgI family protein Sulfatase PF00884.23 KXG49657.1 - 2.4e-79 266.9 0.0 3e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KXG49657.1 - 0.0047 15.6 0.0 0.0069 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 KXG49657.1 - 0.0047 17.2 0.1 0.015 15.6 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KXG49657.1 - 0.017 14.7 0.6 0.16 11.5 0.5 2.5 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 KXG49657.1 - 0.028 14.3 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function Sulfatase_C PF14707.6 KXG49657.1 - 0.046 14.4 2.5 0.77 10.5 1.1 2.6 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Ribonuc_L-PSP PF01042.21 KXG49658.1 - 3.1e-19 69.2 0.1 5.3e-19 68.4 0.1 1.4 1 1 0 1 1 1 1 Endoribonuclease L-PSP Aldedh PF00171.22 KXG49659.1 - 2.4e-144 481.3 0.0 3.2e-144 480.9 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Amidohydro_2 PF04909.14 KXG49659.1 - 5.2e-39 134.8 0.0 7.9e-35 121.0 0.0 2.2 1 1 1 2 2 2 2 Amidohydrolase 3-HAO PF06052.12 KXG49660.1 - 3e-36 124.3 0.0 4.2e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KXG49660.1 - 0.0027 17.4 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXG49660.1 - 0.0048 16.5 0.0 0.0075 15.9 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 KXG49660.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 ARD/ARD' family Zn_clus PF00172.18 KXG49661.1 - 3.3e-10 39.9 10.4 3.3e-10 39.9 10.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXG49661.1 - 2.3e-07 30.1 0.0 4.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KXG49661.1 - 0.001 18.0 0.1 0.0083 15.0 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain NinF PF05810.12 KXG49661.1 - 0.0099 15.7 3.2 0.021 14.7 3.2 1.4 1 0 0 1 1 1 1 NinF protein Rep_fac-A_C PF08646.10 KXG49661.1 - 0.035 13.8 3.8 0.079 12.7 3.8 1.5 1 0 0 1 1 1 0 Replication factor-A C terminal domain DUF1338 PF07063.13 KXG49662.1 - 1.4e-107 359.7 0.0 1.6e-107 359.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) ADH_zinc_N PF00107.26 KXG49663.1 - 1.6e-24 86.3 0.2 2.9e-24 85.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG49663.1 - 1.4e-14 55.3 0.1 3.4e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG49663.1 - 1e-08 35.0 0.5 3.2e-07 30.2 0.0 2.7 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Asparaginase PF00710.20 KXG49664.1 - 2.6e-59 200.0 0.0 3.9e-59 199.4 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KXG49664.1 - 6.7e-28 97.2 0.1 1.9e-27 95.8 0.1 1.8 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KXG49664.1 - 5.4e-09 36.5 0.0 5.7e-08 33.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG49664.1 - 5.9e-08 33.1 0.4 0.00024 21.6 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXG49664.1 - 7.9e-07 29.3 1.1 0.00056 20.2 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KXG49664.1 - 8.6e-07 28.8 0.4 0.0025 18.2 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXG49664.1 - 1.5e-05 25.2 0.1 3.9e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) MTTB PF06253.11 KXG49664.1 - 0.056 11.4 0.3 0.083 10.9 0.3 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) NmrA PF05368.13 KXG49665.1 - 3.6e-71 239.4 0.0 4.3e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAP PF00956.18 KXG49666.1 - 1.4e-32 112.9 8.1 5.6e-29 101.2 3.1 2.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Syntaxin-6_N PF09177.11 KXG49667.1 - 1.4e-25 89.8 2.6 1.9e-25 89.3 0.3 2.2 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KXG49667.1 - 0.00042 20.3 0.6 0.00042 20.3 0.6 2.2 2 0 0 2 2 2 1 SNARE domain Prominin PF05478.11 KXG49667.1 - 0.00082 17.5 0.1 0.0013 16.8 0.1 1.3 1 0 0 1 1 1 1 Prominin ApoLp-III PF07464.11 KXG49667.1 - 0.005 16.9 0.5 0.93 9.6 0.0 2.6 3 0 0 3 3 3 1 Apolipophorin-III precursor (apoLp-III) DUF2205 PF10224.9 KXG49667.1 - 0.017 15.1 1.2 14 5.8 0.0 3.4 3 0 0 3 3 3 0 Short coiled-coil protein DUF4795 PF16043.5 KXG49667.1 - 0.073 12.7 5.2 0.66 9.5 5.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Laminin_II PF06009.12 KXG49667.1 - 0.079 13.0 1.7 5.8 6.9 0.7 2.6 2 1 0 2 2 2 0 Laminin Domain II Baculo_PEP_C PF04513.12 KXG49667.1 - 0.11 12.6 2.5 0.8 9.7 1.3 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus STAT_alpha PF01017.20 KXG49667.1 - 0.11 12.4 4.3 0.35 10.7 4.3 1.9 1 1 0 1 1 1 0 STAT protein, all-alpha domain Syntaxin_2 PF14523.6 KXG49667.1 - 0.12 12.8 1.3 0.2 12.1 0.2 1.9 2 0 0 2 2 2 0 Syntaxin-like protein NPV_P10 PF05531.12 KXG49667.1 - 0.14 12.6 6.9 21 5.6 0.1 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 KXG49667.1 - 0.18 12.1 1.8 0.69 10.2 0.5 2.4 2 2 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.11 KXG49667.1 - 0.25 11.1 2.4 1.5 8.6 0.3 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF2072 PF09845.9 KXG49667.1 - 0.39 11.0 2.5 0.31 11.3 0.4 1.9 1 1 1 2 2 2 0 Zn-ribbon containing protein DUF1664 PF07889.12 KXG49667.1 - 0.41 10.7 6.2 4.1 7.5 1.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KXG49667.1 - 0.64 10.2 11.7 1.6 8.9 4.2 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF2730 PF10805.8 KXG49667.1 - 0.77 9.9 5.1 17 5.6 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) UPF0242 PF06785.11 KXG49667.1 - 0.97 9.5 10.7 0.75 9.9 0.6 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 KXG49667.1 - 1.1 9.3 4.5 1.3 9.0 0.1 2.9 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.17 KXG49667.1 - 4.4 7.2 6.9 24 4.9 0.6 3.1 3 0 0 3 3 3 0 Prefoldin subunit p450 PF00067.22 KXG49668.1 - 2.1e-62 211.4 0.0 2.8e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.25 KXG49669.1 - 8.4e-21 74.4 0.0 1e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXG49669.1 - 1.7e-10 41.1 0.0 2.4e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXG49669.1 - 1.5e-09 37.9 0.0 1.8e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXG49669.1 - 6.3e-07 30.1 0.1 7.3e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG49669.1 - 7.7e-07 29.0 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KXG49669.1 - 0.0015 18.7 0.0 0.0019 18.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXG49669.1 - 0.013 15.6 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 KXG49669.1 - 0.079 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase SKG6 PF08693.10 KXG49671.1 - 1.1e-06 27.9 0.1 2.9e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CD34_antigen PF06365.12 KXG49671.1 - 0.0028 17.3 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family Podoplanin PF05808.11 KXG49671.1 - 0.0048 17.0 0.4 0.0082 16.3 0.4 1.4 1 0 0 1 1 1 1 Podoplanin Phage_HK97_TLTM PF06120.11 KXG49671.1 - 0.028 13.6 0.3 0.04 13.1 0.3 1.1 1 0 0 1 1 1 0 Tail length tape measure protein CbtA PF09490.10 KXG49671.1 - 0.053 13.3 0.1 0.076 12.8 0.1 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) BatA PF07584.11 KXG49671.1 - 0.079 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Mid2 PF04478.12 KXG49671.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Gram_pos_anchor PF00746.21 KXG49671.1 - 0.1 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF5305 PF17231.2 KXG49671.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Beta-APP PF03494.13 KXG49671.1 - 0.22 11.4 3.2 0.37 10.7 3.2 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) MGC-24 PF05283.11 KXG49671.1 - 0.81 10.1 9.7 0.37 11.2 7.0 1.8 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF1180 PF06679.12 KXG49671.1 - 9.6 6.6 10.1 4.1 7.8 7.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) VIT PF08487.10 KXG49672.1 - 1.2e-31 109.1 0.0 2.5e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KXG49672.1 - 2.6e-26 92.4 0.0 4.4e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KXG49672.1 - 1.6e-11 43.9 0.1 4.5e-11 42.5 0.1 1.7 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 KXG49672.1 - 1.7e-11 44.7 0.0 2.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXG49672.1 - 8.5e-09 36.0 0.0 1.7e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain RNA_pol_Rpb1_R PF05001.13 KXG49672.1 - 9.4e-05 22.6 63.6 0.0083 16.4 9.6 5.4 5 0 0 5 5 5 3 RNA polymerase Rpb1 C-terminal repeat VWA_CoxE PF05762.14 KXG49672.1 - 0.0048 16.3 0.0 0.009 15.4 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein B3_4 PF03483.17 KXG49673.1 - 2.1e-21 76.4 0.0 2.8e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 B3/4 domain Glyco_hydro_32C PF08244.12 KXG49674.1 - 4.7e-25 88.4 0.1 7.4e-25 87.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 KXG49674.1 - 2.8e-13 50.1 0.0 4.5e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain BTB PF00651.31 KXG49675.1 - 8e-05 22.8 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Methyltransf_32 PF13679.6 KXG49676.1 - 2.4e-22 79.6 0.8 1.1e-21 77.4 0.8 1.9 1 1 0 1 1 1 1 Methyltransferase domain Abhydrolase_2 PF02230.16 KXG49677.1 - 5e-14 52.6 0.0 7.2e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KXG49677.1 - 0.0028 18.3 0.3 0.0038 17.8 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3759 PF12585.8 KXG49678.1 - 3.9e-39 132.6 10.4 4.6e-39 132.4 10.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Serine_protease PF18405.1 KXG49678.1 - 0.18 10.9 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Gammaproteobacterial serine protease EXS PF03124.14 KXG49679.1 - 5.1e-97 325.1 37.0 6.5e-97 324.8 37.0 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KXG49679.1 - 1.4e-77 262.2 12.5 1.4e-77 262.2 12.5 2.1 2 1 0 2 2 2 1 SPX domain CagE_TrbE_VirB PF03135.14 KXG49679.1 - 0.047 13.8 2.0 0.098 12.7 2.0 1.4 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system Cas_DxTHG PF09455.10 KXG49679.1 - 0.6 9.6 2.6 0.47 10.0 0.7 1.7 1 1 1 2 2 2 0 CRISPR-associated (Cas) DxTHG family Aa_trans PF01490.18 KXG49680.1 - 7.2e-40 136.9 37.7 8.4e-40 136.7 37.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 KXG49680.1 - 0.0031 16.4 47.9 0.4 9.5 47.9 2.2 1 1 0 1 1 1 1 Amino acid permease PP-binding PF00550.25 KXG49681.1 - 1.9e-13 50.5 0.2 2.2e-13 50.3 0.2 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Fas_alpha_ACP PF18325.1 KXG49681.1 - 0.049 14.0 0.7 0.053 13.9 0.7 1.0 1 0 0 1 1 1 0 Fatty acid synthase subunit alpha Acyl carrier domain WGG PF10273.9 KXG49681.1 - 0.12 13.1 0.3 5.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Pre-rRNA-processing protein TSR2 LysM PF01476.20 KXG49682.1 - 1.2e-21 76.5 1.3 8.7e-05 22.5 0.0 4.5 5 0 0 5 5 5 4 LysM domain OapA PF04225.12 KXG49682.1 - 0.0048 17.0 0.0 2.1 8.5 0.0 2.8 3 0 0 3 3 3 2 Opacity-associated protein A LysM-like domain FhuF_C PF11575.8 KXG49682.1 - 2.4 8.2 5.9 62 3.7 0.1 3.7 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain Bax1-I PF01027.20 KXG49683.1 - 5.7e-51 173.3 30.8 6.5e-51 173.1 30.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spore_YhaL PF14147.6 KXG49683.1 - 0.15 11.8 1.2 0.37 10.5 0.2 2.2 2 0 0 2 2 2 0 Sporulation protein YhaL DUF1011 PF06237.12 KXG49683.1 - 1.6 9.1 14.6 8.1 6.8 2.3 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1011) Aa_trans PF01490.18 KXG49684.1 - 6.1e-93 311.7 13.8 8.6e-93 311.2 13.8 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KXG49684.1 - 3e-06 26.6 15.1 3e-06 26.6 15.1 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family adh_short PF00106.25 KXG49685.1 - 5.3e-36 123.9 0.0 6.8e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG49685.1 - 5.5e-28 98.1 0.0 7.7e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG49685.1 - 0.00027 20.9 0.0 0.021 14.7 0.0 2.2 2 0 0 2 2 2 1 KR domain DNA_ligase_A_C PF04679.15 KXG49685.1 - 0.051 14.2 0.2 0.25 11.9 0.0 2.0 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region DcuA_DcuB PF03605.14 KXG49685.1 - 0.12 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF1479 PF07350.12 KXG49686.1 - 1.2e-167 557.9 0.0 1.4e-167 557.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) MT0933_antitox PF14013.6 KXG49687.1 - 0.015 15.6 5.5 0.23 11.8 5.5 2.6 1 1 0 1 1 1 0 MT0933-like antitoxin protein EMC1_C PF07774.13 KXG49689.1 - 1e-78 263.9 0.0 4.8e-78 261.7 0.0 2.0 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KXG49689.1 - 1.7e-28 99.8 21.6 1.6e-27 96.6 7.0 3.4 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.21 KXG49689.1 - 1.7e-07 30.8 1.8 0.12 12.4 0.2 5.1 4 0 0 4 4 4 2 PQQ enzyme repeat FA_hydroxylase PF04116.13 KXG49690.1 - 3e-22 79.4 12.8 3e-22 79.4 12.8 2.6 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily CRAL_TRIO PF00650.20 KXG49691.1 - 9.6e-25 87.2 0.0 1.3e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXG49691.1 - 3.3e-11 43.2 0.3 1.1e-10 41.5 0.3 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SNase PF00565.17 KXG49692.1 - 3.4e-75 249.5 0.0 6.4e-24 84.5 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KXG49692.1 - 5.2e-23 81.4 0.0 3.5e-22 78.7 0.0 2.3 2 0 0 2 2 2 1 Tudor domain SMN PF06003.12 KXG49692.1 - 0.0004 19.7 0.0 0.00074 18.9 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 KXG49692.1 - 0.036 14.5 0.0 0.25 11.9 0.0 2.4 3 0 0 3 3 3 0 Agenet domain Sod_Cu PF00080.20 KXG49693.1 - 1.3e-45 155.1 4.4 1.5e-45 154.9 4.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TAL_FSA PF00923.19 KXG49694.1 - 7.7e-94 314.2 0.3 8.9e-94 314.0 0.3 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Beach PF02138.18 KXG49695.1 - 1.5e-119 398.5 1.2 1.5e-119 398.5 0.1 1.6 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 KXG49695.1 - 6.2e-13 48.7 0.1 1.4e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 KXG49695.1 - 8e-10 39.1 0.0 2.3e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 KXG49695.1 - 5.2e-06 27.1 1.8 0.044 14.7 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Peptidase_S8 PF00082.22 KXG49696.1 - 6.2e-39 134.0 10.8 1e-38 133.3 10.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXG49696.1 - 6.9e-20 71.5 0.2 1.2e-19 70.7 0.2 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 UQ_con PF00179.26 KXG49697.1 - 3.2e-39 133.8 0.0 4e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ABC_tran PF00005.27 KXG49698.1 - 3.1e-54 183.2 0.1 1.5e-31 109.7 0.1 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXG49698.1 - 1.1e-51 176.2 23.0 2.7e-33 115.8 3.6 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KXG49698.1 - 2e-07 30.7 6.4 0.0064 16.0 0.6 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXG49698.1 - 1e-06 29.4 0.3 0.0014 19.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KXG49698.1 - 7.9e-06 25.9 0.3 0.15 11.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXG49698.1 - 6.5e-05 23.2 1.9 3.2 8.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KXG49698.1 - 6.7e-05 22.8 0.3 0.22 11.4 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXG49698.1 - 0.00022 21.3 0.5 0.053 13.6 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 KXG49698.1 - 0.00039 20.6 1.1 0.084 12.9 0.2 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 KXG49698.1 - 0.001 19.5 0.2 1.2 9.5 0.1 2.9 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 KXG49698.1 - 0.0015 17.7 0.1 0.02 14.0 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 KXG49698.1 - 0.0021 17.8 0.0 0.86 9.3 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_29 PF13555.6 KXG49698.1 - 0.0026 17.5 3.7 0.77 9.5 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KXG49698.1 - 0.0037 16.9 0.6 0.64 9.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 KXG49698.1 - 0.0058 15.9 1.1 1.7 7.9 0.1 3.0 3 0 0 3 3 3 1 Zeta toxin AAA_7 PF12775.7 KXG49698.1 - 0.029 13.9 0.2 4.5 6.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region TIP49 PF06068.13 KXG49698.1 - 0.035 13.3 1.0 6.2 5.9 0.2 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain DEAD PF00270.29 KXG49698.1 - 0.043 13.6 0.3 5.1 6.8 0.0 3.3 3 0 0 3 3 3 0 DEAD/DEAH box helicase cobW PF02492.19 KXG49698.1 - 0.049 13.2 3.3 0.86 9.2 0.2 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KXG49698.1 - 0.054 13.9 1.0 11 6.4 0.1 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KXG49698.1 - 0.11 11.9 0.9 2 7.7 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 KXG49698.1 - 0.13 12.0 1.1 14 5.3 0.1 3.3 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 KXG49698.1 - 0.19 11.1 0.5 12 5.3 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein TrwB_AAD_bind PF10412.9 KXG49698.1 - 0.27 10.1 2.7 3.8 6.3 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Polysacc_deac_1 PF01522.21 KXG49700.1 - 6.2e-19 68.1 0.0 1.2e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXG49700.1 - 1.4e-05 24.9 0.1 4.4e-05 23.2 0.1 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KXG49700.1 - 0.07 11.5 0.0 0.092 11.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) DUF3519 PF12033.8 KXG49700.1 - 0.096 13.1 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3519) Amidase PF01425.21 KXG49701.1 - 8.1e-92 308.5 0.1 1e-91 308.2 0.1 1.1 1 0 0 1 1 1 1 Amidase adh_short_C2 PF13561.6 KXG49702.1 - 3.5e-59 200.2 0.2 5.5e-59 199.5 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG49702.1 - 1e-40 139.3 0.0 2.5e-40 138.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG49702.1 - 0.0008 19.4 0.1 0.0022 17.9 0.1 1.7 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 KXG49702.1 - 0.0054 17.4 0.1 0.015 16.0 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Glycos_transf_2 PF00535.26 KXG49702.1 - 0.074 12.9 0.3 4.1 7.2 0.2 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Methyltransf_11 PF08241.12 KXG49702.1 - 0.12 13.0 0.0 0.27 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF5448 PF17526.2 KXG49702.1 - 0.17 12.0 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5448) Fungal_trans PF04082.18 KXG49703.1 - 2.3e-21 76.0 0.3 4.8e-21 75.0 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXG49703.1 - 7.8e-08 32.4 15.1 1.8e-05 24.9 4.1 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXG49703.1 - 0.0032 18.2 13.8 0.0068 17.2 2.7 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXG49703.1 - 0.0039 17.6 1.4 0.0039 17.6 1.4 3.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-UBR PF02207.20 KXG49703.1 - 0.11 12.7 0.7 0.21 11.8 0.7 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-C2H2_jaz PF12171.8 KXG49703.1 - 0.12 12.7 0.2 0.25 11.7 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AAA_12 PF13087.6 KXG49704.1 - 9.7e-42 142.8 0.0 1.4e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXG49704.1 - 9e-24 84.7 0.0 8e-23 81.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXG49704.1 - 1.9e-08 34.3 0.0 3.1e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXG49704.1 - 5.5e-07 30.0 0.0 6.1e-06 26.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXG49704.1 - 0.0017 18.2 0.0 0.13 11.9 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KXG49704.1 - 0.0098 15.9 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KXG49704.1 - 0.028 13.7 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KXG49704.1 - 0.038 13.4 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.29 KXG49704.1 - 0.047 13.5 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase WD40 PF00400.32 KXG49705.1 - 1.1e-16 60.9 0.8 0.24 12.3 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG49705.1 - 0.0082 16.4 0.0 12 6.3 0.0 3.8 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KXG49705.1 - 0.1 11.5 0.0 0.28 10.1 0.0 1.6 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PRP38 PF03371.15 KXG49707.1 - 5.5e-64 215.2 0.0 6.9e-64 214.9 0.0 1.0 1 0 0 1 1 1 1 PRP38 family DUF3445 PF11927.8 KXG49708.1 - 2.2e-77 259.7 0.0 2.8e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) RTA1 PF04479.13 KXG49709.1 - 7.6e-64 215.1 9.6 7.6e-64 215.1 9.6 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF5518 PF17647.1 KXG49709.1 - 0.019 15.1 3.1 0.019 15.1 3.1 2.9 3 1 0 3 3 3 0 Family of unknown function (DUF5518) DUF4175 PF13779.6 KXG49709.1 - 4 5.2 3.7 9.9 3.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Sugar_tr PF00083.24 KXG49710.1 - 2.3e-119 399.2 21.3 3.5e-119 398.6 21.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG49710.1 - 1.3e-24 86.9 41.0 3e-24 85.6 36.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily WSC PF01822.19 KXG49712.1 - 1.9e-09 37.6 10.4 1.9e-09 37.6 10.4 2.2 2 0 0 2 2 2 1 WSC domain Podoplanin PF05808.11 KXG49712.1 - 2.9e-05 24.2 4.1 5.8e-05 23.2 4.1 1.5 1 0 0 1 1 1 1 Podoplanin DUF5305 PF17231.2 KXG49712.1 - 0.017 14.5 0.9 0.026 13.9 0.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Amnionless PF14828.6 KXG49712.1 - 0.019 13.8 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 Amnionless Pap_E4 PF02711.14 KXG49712.1 - 1.5 9.9 7.2 4.2 8.4 7.2 1.7 1 0 0 1 1 1 0 E4 protein SKG6 PF08693.10 KXG49712.1 - 6.1 6.3 6.5 2 7.9 0.3 2.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF4690 PF15756.5 KXG49712.1 - 9.2 6.9 16.2 3.6 8.2 10.7 2.5 1 1 1 2 2 2 0 Small Novel Rich in Cartilage HNH_2 PF13391.6 KXG49713.1 - 8.9e-08 32.2 0.0 2.8e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 HNH endonuclease AMP-binding PF00501.28 KXG49714.1 - 6.8e-52 176.5 0.0 9.2e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG49714.1 - 0.00035 21.5 0.0 0.00077 20.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IMS PF00817.20 KXG49715.1 - 8.7e-36 123.2 0.0 6.6e-34 117.1 0.0 2.3 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KXG49715.1 - 5.3e-14 52.9 0.0 1.4e-13 51.5 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KXG49715.1 - 1.6e-12 46.8 1.8 3.6e-12 45.6 1.8 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger DDOST_48kD PF03345.14 KXG49718.1 - 1.1e-155 518.6 0.0 1.3e-155 518.4 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta NAPRTase_C PF17956.1 KXG49718.1 - 0.028 14.9 0.0 0.066 13.6 0.0 1.7 1 1 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain DUF11 PF01345.18 KXG49718.1 - 0.082 13.2 0.0 1.1 9.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF11 DUF1116 PF06545.11 KXG49718.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) Pet191_N PF10203.9 KXG49719.1 - 1.5e-28 98.8 4.5 1.9e-28 98.5 4.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KXG49719.1 - 0.094 12.7 3.6 1.1 9.3 0.4 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like PAN_3 PF08277.12 KXG49719.1 - 0.1 12.4 0.6 0.24 11.2 0.3 1.7 2 0 0 2 2 2 0 PAN-like domain CX9C PF16860.5 KXG49719.1 - 0.15 12.1 4.6 5.6 7.1 0.2 2.4 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Abhydrolase_1 PF00561.20 KXG49720.1 - 1.3e-23 84.0 0.0 1.3e-22 80.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KXG49720.1 - 3.8e-23 80.8 0.2 1.1e-22 79.3 0.1 1.9 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KXG49720.1 - 2.1e-05 23.9 0.0 0.0097 15.2 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 KXG49720.1 - 0.0011 18.7 0.0 0.44 10.2 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Tannase PF07519.11 KXG49722.1 - 1.8e-148 495.4 3.6 2.1e-148 495.1 3.6 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Metallophos PF00149.28 KXG49723.1 - 2.3e-08 34.8 1.2 4.9e-08 33.7 1.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXG49723.1 - 4e-07 30.4 0.0 8.6e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ImpE PF07024.13 KXG49723.1 - 0.093 12.8 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 ImpE protein SNF2_N PF00176.23 KXG49724.1 - 6.4e-75 252.1 0.8 1.9e-74 250.5 0.8 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 KXG49724.1 - 2.7e-24 85.0 0.3 9e-24 83.4 0.3 1.9 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 KXG49724.1 - 9.5e-22 77.4 1.5 5.5e-20 71.8 0.0 3.8 3 1 1 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 KXG49724.1 - 1.9e-19 69.7 15.7 1.9e-19 69.7 15.7 3.5 3 0 0 3 3 3 1 HSA SnAC PF14619.6 KXG49724.1 - 1.1e-14 54.8 1.2 1.1e-14 54.8 1.2 4.0 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 KXG49724.1 - 2.9e-12 46.1 1.7 2.9e-12 46.1 1.7 2.2 2 0 0 2 2 2 1 QLQ ResIII PF04851.15 KXG49724.1 - 4.3e-10 39.8 0.0 4.3e-10 39.8 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PorB PF11565.8 KXG49724.1 - 0.084 13.3 0.6 17 5.9 0.2 2.9 2 0 0 2 2 2 0 Alpha helical Porin B BAR PF03114.18 KXG49725.1 - 1.8e-49 168.5 5.9 2.3e-49 168.2 5.9 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KXG49725.1 - 9.2e-07 28.3 3.3 1.3e-06 27.8 3.3 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking APG6_N PF17675.1 KXG49725.1 - 0.00099 19.6 4.9 0.00099 19.6 4.9 1.7 2 0 0 2 2 2 1 Apg6 coiled-coil region Ada_Zn_binding PF02805.16 KXG49726.1 - 1.1e-29 102.2 4.9 1.7e-29 101.6 4.9 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KXG49726.1 - 4.4e-10 39.4 0.0 7.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KXG49726.1 - 6e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Dynamin_N PF00350.23 KXG49727.1 - 6.7e-32 110.9 0.2 1.5e-31 109.7 0.2 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KXG49727.1 - 1.7e-28 99.7 0.1 1e-27 97.1 0.1 2.2 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KXG49727.1 - 4.9e-06 26.6 0.2 3.6e-05 23.8 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 KXG49727.1 - 0.00014 21.9 3.0 0.00028 21.0 0.6 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain DUF5082 PF16888.5 KXG49727.1 - 0.0065 16.7 4.6 5.1 7.4 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF5082) AAA_15 PF13175.6 KXG49727.1 - 0.066 12.9 2.4 0.071 12.8 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 KXG49727.1 - 0.076 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KXG49727.1 - 0.13 12.5 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KXG49727.1 - 0.16 11.5 0.0 15 5.1 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 KXG49727.1 - 0.47 10.8 2.6 7 7.0 0.0 3.3 4 0 0 4 4 4 0 AAA ATPase domain AAA_23 PF13476.6 KXG49727.1 - 2 8.8 0.0 2 8.8 0.0 3.2 3 2 0 3 3 3 0 AAA domain Prefoldin PF02996.17 KXG49727.1 - 2.3 8.1 7.7 1.1 9.2 0.1 3.8 4 0 0 4 4 4 0 Prefoldin subunit Ribosomal_L2_C PF03947.18 KXG49728.1 - 8.8e-43 145.5 5.2 1.6e-42 144.7 5.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KXG49728.1 - 1.6e-12 47.2 0.1 4.2e-12 45.9 0.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM1 PF15612.6 KXG49729.1 - 9.7e-08 31.4 0.0 2.2e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF1770 PF08589.10 KXG49730.1 - 2.9e-31 108.4 1.1 4.2e-31 107.9 1.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) PfkB PF00294.24 KXG49731.1 - 2.6e-69 233.8 0.1 2.9e-69 233.7 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KXG49731.1 - 0.022 14.2 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.9 KXG49732.1 - 3.5e-70 236.7 0.2 3e-69 233.6 0.0 2.1 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KXG49732.1 - 1.3e-24 87.4 1.0 5.9e-22 78.8 0.4 2.5 2 0 0 2 2 2 2 Telomerase activating protein Est1 zf-C2H2 PF00096.26 KXG49733.1 - 0.032 14.7 0.7 0.032 14.7 0.7 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXG49733.1 - 2.2 9.4 10.2 1.2 10.2 0.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Fungal_trans PF04082.18 KXG49734.1 - 4.4e-15 55.4 4.2 4.4e-15 55.4 4.2 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Pkinase PF00069.25 KXG49735.1 - 8.3e-70 235.2 0.0 1.7e-69 234.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG49735.1 - 8.2e-49 166.2 0.0 9.6e-48 162.7 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KXG49735.1 - 6.7e-25 87.3 0.0 1.2e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 KXG49735.1 - 4.1e-16 59.2 0.0 9.5e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KXG49735.1 - 9.6e-14 51.3 0.1 5e-13 48.9 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 KXG49735.1 - 9e-07 28.5 0.0 0.0026 17.1 0.0 2.3 1 1 0 2 2 2 2 Kinase-like RA PF00788.23 KXG49735.1 - 0.0026 18.4 0.0 0.0048 17.5 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pkinase_fungal PF17667.1 KXG49735.1 - 0.0032 16.3 0.0 0.0063 15.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase tRNA_lig_CPD PF08302.11 KXG49735.1 - 0.03 13.8 0.4 0.05 13.1 0.4 1.2 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Kdo PF06293.14 KXG49735.1 - 0.13 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L5_C PF00673.21 KXG49736.1 - 4.8e-30 103.6 0.0 7.7e-30 102.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KXG49736.1 - 0.00023 21.4 0.0 0.00043 20.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 UCH PF00443.29 KXG49737.1 - 9.6e-17 61.3 0.0 2.4e-16 60.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXG49737.1 - 1.3e-15 57.9 0.0 1.4e-06 28.1 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EnY2 PF10163.9 KXG49737.1 - 0.086 13.2 0.1 0.25 11.8 0.1 1.7 1 0 0 1 1 1 0 Transcription factor e(y)2 Pep3_Vps18 PF05131.14 KXG49738.1 - 4e-44 150.0 0.0 1.7e-43 148.0 0.0 2.1 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KXG49738.1 - 1.3e-06 28.3 5.1 0.00042 20.2 0.0 3.5 3 1 2 5 5 5 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 KXG49738.1 - 0.00031 20.3 0.2 0.00062 19.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KXG49738.1 - 0.00079 19.3 0.2 0.0018 18.2 0.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXG49738.1 - 0.00094 19.0 0.5 0.0025 17.6 0.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXG49738.1 - 0.0031 17.2 4.8 0.0031 17.2 4.8 1.9 2 0 0 2 2 2 1 RING-like zinc finger DUF2175 PF09943.9 KXG49738.1 - 0.0047 17.2 0.0 0.042 14.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_2 PF13639.6 KXG49738.1 - 0.0099 16.2 1.0 0.024 14.9 1.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXG49738.1 - 0.032 14.2 0.4 0.079 13.0 0.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger RPN1_RPN2_N PF17781.1 KXG49738.1 - 0.068 12.6 0.2 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 RPN1/RPN2 N-terminal domain zf-C3HC4 PF00097.25 KXG49738.1 - 0.078 12.9 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXG49738.1 - 0.12 12.6 0.4 0.49 10.7 0.6 1.9 2 0 0 2 2 1 0 RING-H2 zinc finger domain Vps39_2 PF10367.9 KXG49738.1 - 0.16 12.5 0.0 0.45 11.0 0.0 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3H2C3 PF17122.5 KXG49738.1 - 1.2 9.2 4.4 0.31 11.1 0.9 1.9 2 0 0 2 2 2 0 Zinc-finger Pkinase PF00069.25 KXG49739.1 - 1.2e-53 182.1 0.0 1.7e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG49739.1 - 1.8e-34 119.2 0.0 2.6e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG49739.1 - 1.6e-10 40.8 0.0 3.7e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KXG49739.1 - 0.014 14.7 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cas_APE2256 PF09651.10 KXG49739.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) Sad1_UNC PF07738.13 KXG49740.1 - 2.4e-30 105.2 0.1 4.4e-30 104.4 0.1 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CEP63 PF17045.5 KXG49740.1 - 0.014 15.3 5.4 0.025 14.5 5.4 1.3 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa HNH_2 PF13391.6 KXG49741.1 - 0.0019 18.3 0.1 0.0045 17.1 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease Paired_CXXCH_1 PF09699.10 KXG49741.1 - 0.26 11.1 2.2 3.3 7.5 2.2 2.3 1 1 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) Spo12 PF05032.12 KXG49742.1 - 9.9e-17 60.6 0.8 1.6e-16 59.9 0.8 1.4 1 0 0 1 1 1 1 Spo12 family Acyl-CoA_dh_1 PF00441.24 KXG49743.1 - 5.1e-31 107.9 2.3 8.4e-31 107.2 2.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXG49743.1 - 1.7e-20 73.0 0.0 5.3e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXG49743.1 - 9.3e-14 52.1 0.1 1.8e-13 51.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXG49743.1 - 5.1e-13 49.5 3.1 8.9e-13 48.7 3.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MMR_HSR1 PF01926.23 KXG49744.1 - 1.3e-16 60.7 1.5 3.7e-14 52.8 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KXG49744.1 - 3.8e-07 29.7 0.2 1.4e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXG49744.1 - 1.6e-05 24.9 0.2 0.013 15.4 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 KXG49744.1 - 0.0049 16.2 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 AIG1 family PIN_9 PF18477.1 KXG49744.1 - 0.015 15.6 0.7 2.5 8.4 0.2 2.6 2 0 0 2 2 2 0 PIN like domain cobW PF02492.19 KXG49744.1 - 0.035 13.7 0.4 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KXG49744.1 - 0.04 14.0 7.6 0.25 11.4 0.2 3.3 3 2 0 3 3 3 0 Dynamin family LTV PF04180.14 KXG49745.1 - 6.2e-118 394.9 6.3 7.1e-118 394.7 6.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein PLDc_2 PF13091.6 KXG49746.1 - 1.2e-15 57.6 0.0 7.5e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KXG49746.1 - 5.9e-09 35.7 0.5 0.0053 16.9 0.4 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif NDUFA12 PF05071.16 KXG49747.1 - 8.7e-31 106.6 0.4 1.1e-30 106.3 0.4 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 TPR_14 PF13428.6 KXG49748.1 - 1.4e-07 31.7 29.4 1.1 10.3 0.6 8.6 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 KXG49748.1 - 5.9e-05 22.7 3.8 7.1 6.6 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXG49748.1 - 0.00031 20.6 12.7 5.7 7.3 0.2 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXG49748.1 - 0.0013 19.2 13.3 0.18 12.3 0.3 6.2 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXG49748.1 - 0.0024 17.9 9.5 83 3.8 0.0 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXG49748.1 - 0.0054 17.0 13.7 15 6.0 0.1 6.2 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXG49748.1 - 0.016 15.8 19.9 0.66 10.7 0.4 6.6 6 1 1 7 7 7 0 Tetratricopeptide repeat PUL PF08324.11 KXG49748.1 - 0.021 14.1 0.1 0.76 9.0 0.0 2.7 2 0 0 2 2 2 0 PUL domain ANAPC3 PF12895.7 KXG49748.1 - 0.13 12.5 0.0 0.86 9.9 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RIX1 PF08167.12 KXG49749.1 - 1.4e-61 207.5 5.0 2.5e-60 203.5 3.1 2.5 2 0 0 2 2 2 2 rRNA processing/ribosome biogenesis Aldedh PF00171.22 KXG49750.1 - 2.5e-181 603.3 1.9 2.8e-181 603.1 1.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 KXG49751.1 - 9.3e-155 515.6 0.3 1.2e-154 515.3 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NmrA PF05368.13 KXG49751.1 - 1.1e-25 90.6 0.0 3.4e-25 89.0 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KXG49751.1 - 2.2e-06 27.7 0.0 4.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KXG49751.1 - 0.00068 20.1 0.0 0.0045 17.4 0.0 2.5 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXG49751.1 - 0.0013 19.0 0.1 0.024 14.9 0.0 2.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXG49751.1 - 0.0019 17.7 0.0 0.0054 16.2 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KXG49751.1 - 0.086 13.1 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.10 KXG49751.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 KR domain Oxidored_FMN PF00724.20 KXG49752.1 - 9.4e-34 117.2 0.0 1.4e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DAO PF01266.24 KXG49753.1 - 5.3e-45 154.5 0.1 6.3e-45 154.3 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXG49753.1 - 0.0033 16.7 0.0 0.056 12.7 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG49753.1 - 0.0036 17.3 1.6 0.81 9.7 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXG49753.1 - 0.055 12.6 0.0 0.13 11.4 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXG49753.1 - 0.058 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Aldedh PF00171.22 KXG49754.1 - 4.2e-181 602.5 0.9 4.8e-181 602.3 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family p450 PF00067.22 KXG49755.1 - 1e-46 159.7 0.0 1.5e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Cupin_3 PF05899.12 KXG49756.1 - 3.9e-08 32.9 0.3 5.8e-08 32.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KXG49756.1 - 9.6e-05 22.0 0.2 0.00016 21.3 0.2 1.4 1 0 0 1 1 1 1 Cupin domain EutQ PF06249.12 KXG49756.1 - 0.2 11.4 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ FMO-like PF00743.19 KXG49757.1 - 3.8e-12 45.4 0.0 8.8e-12 44.2 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXG49757.1 - 2.6e-09 36.8 0.0 1.3e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG49757.1 - 1.4e-07 31.6 0.0 3.5e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXG49757.1 - 7e-06 25.5 0.0 4.5e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG49757.1 - 9e-06 25.0 0.0 0.00029 20.1 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KXG49757.1 - 0.004 16.5 0.3 1.1 8.5 0.0 2.3 1 1 1 2 2 2 2 FAD binding domain Integrin_b_cyt PF08725.11 KXG49757.1 - 0.0077 15.9 0.3 0.018 14.7 0.3 1.6 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain GIDA PF01134.22 KXG49757.1 - 0.019 14.1 1.4 1.6 7.7 0.1 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KXG49757.1 - 0.066 13.2 0.8 4.6 7.2 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KXG49757.1 - 0.075 12.4 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KXG49757.1 - 0.086 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KXG49757.1 - 0.091 12.3 0.3 16 5.0 0.2 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Fungal_trans_2 PF11951.8 KXG49758.1 - 3.8e-33 114.8 0.5 7.2e-33 113.9 0.5 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain SesA PF17107.5 KXG49759.1 - 8.9e-19 67.9 1.4 1.8e-18 66.9 0.2 1.8 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Spore_III_AB PF09548.10 KXG49759.1 - 0.01 15.9 0.2 0.028 14.5 0.0 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) ALIX_LYPXL_bnd PF13949.6 KXG49759.1 - 0.023 14.0 0.3 0.04 13.2 0.3 1.4 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Casc1_N PF15927.5 KXG49759.1 - 0.03 14.0 1.0 0.055 13.2 1.0 1.4 1 1 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus SesA PF17107.5 KXG49760.1 - 1.3e-25 89.9 0.2 4.8e-25 88.1 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ribosomal_60s PF00428.19 KXG49760.1 - 0.051 14.2 1.1 0.11 13.1 0.2 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ank_2 PF12796.7 KXG49761.1 - 1.5e-60 201.7 0.1 4.5e-08 33.6 0.0 8.0 3 2 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG49761.1 - 1.5e-43 146.6 15.1 2.1e-06 28.1 0.2 11.7 7 3 5 12 12 12 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG49761.1 - 7e-43 144.1 8.7 1.8e-08 34.5 0.1 9.7 5 3 5 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG49761.1 - 1.4e-41 135.7 4.9 0.00059 20.1 0.0 14.8 14 0 0 14 14 14 10 Ankyrin repeat Ank PF00023.30 KXG49761.1 - 5.9e-41 137.2 5.7 4.7e-05 23.6 0.0 14.0 13 1 0 13 13 13 11 Ankyrin repeat DUF1993 PF09351.10 KXG49763.1 - 2.6e-41 141.4 0.0 3.2e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Acetyltransf_3 PF13302.7 KXG49763.1 - 0.0029 18.3 0.0 0.0069 17.1 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF521 PF04412.13 KXG49764.1 - 2.6e-131 438.1 0.0 6.6e-131 436.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF521) DUF126 PF01989.16 KXG49764.1 - 4.7e-29 100.0 0.2 9.2e-29 99.1 0.2 1.5 1 0 0 1 1 1 1 Aconitase X swivel domain GMC_oxred_N PF00732.19 KXG49765.1 - 3.9e-51 174.2 0.0 5.3e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG49765.1 - 4.3e-33 114.9 0.0 6.9e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KXG49765.1 - 0.00011 22.0 1.1 0.00034 20.3 1.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXG49765.1 - 0.00011 21.4 0.1 0.00017 20.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXG49765.1 - 0.003 16.7 0.3 1.3 8.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXG49765.1 - 0.0032 16.7 0.1 0.0092 15.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG49765.1 - 0.019 15.2 0.0 0.045 14.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXG49765.1 - 0.025 13.8 0.0 0.63 9.2 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 KXG49765.1 - 0.22 10.3 0.1 0.34 9.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase AA_permease_2 PF13520.6 KXG49766.1 - 3.5e-39 134.8 46.7 4.2e-39 134.6 46.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG49766.1 - 1.3e-19 70.2 39.0 1.7e-19 69.8 39.0 1.0 1 0 0 1 1 1 1 Amino acid permease SfLAP PF11139.8 KXG49766.1 - 0.00013 21.4 2.1 0.00046 19.7 2.1 2.0 1 1 0 1 1 1 1 Sap, sulfolipid-1-addressing protein DUF3040 PF11239.8 KXG49766.1 - 1.3 9.3 4.3 7.6 6.9 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Fungal_trans_2 PF11951.8 KXG49767.1 - 1.3e-22 80.2 11.1 2.5e-22 79.2 11.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG49767.1 - 2.9e-08 33.7 7.5 6.1e-08 32.7 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_3 PF05899.12 KXG49768.1 - 3.2e-10 39.6 0.2 4.4e-10 39.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KXG49768.1 - 4.9e-05 23.0 0.1 7.6e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 KXG49768.1 - 0.0016 18.2 0.0 0.0019 18.0 0.0 1.1 1 0 0 1 1 1 1 Cupin EutQ PF06249.12 KXG49768.1 - 0.02 14.7 0.1 0.023 14.5 0.1 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ HutD PF05962.11 KXG49768.1 - 0.052 13.5 0.0 0.066 13.2 0.0 1.1 1 0 0 1 1 1 0 HutD AraC_binding_2 PF14525.6 KXG49768.1 - 0.056 13.1 0.0 0.08 12.6 0.0 1.1 1 0 0 1 1 1 0 AraC-binding-like domain CENP-C_C PF11699.8 KXG49768.1 - 0.068 13.4 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 Mif2/CENP-C like DAO PF01266.24 KXG49769.1 - 9.5e-20 71.5 0.0 1.1e-19 71.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF1188 PF06690.11 KXG49769.1 - 0.048 13.2 0.0 0.57 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Malic_M PF03949.15 KXG49769.1 - 0.14 11.4 0.3 3.1 7.0 0.1 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain AA_permease_2 PF13520.6 KXG49770.1 - 8.6e-44 150.0 51.9 9.9e-44 149.8 51.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG49770.1 - 9.6e-16 57.4 44.7 1.3e-15 57.0 44.7 1.1 1 0 0 1 1 1 1 Amino acid permease MBOAT_2 PF13813.6 KXG49771.1 - 4e-21 75.1 4.0 1.5e-20 73.2 4.0 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family adh_short PF00106.25 KXG49772.1 - 3.9e-30 104.8 0.0 5.1e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG49772.1 - 2e-29 102.8 0.0 2.6e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG49772.1 - 0.00036 20.5 0.0 0.00056 19.9 0.0 1.2 1 0 0 1 1 1 1 KR domain SNF2_N PF00176.23 KXG49773.1 - 7.5e-66 222.2 0.0 1.2e-65 221.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KXG49773.1 - 9.2e-17 60.8 0.0 1.8e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KXG49773.1 - 1.4e-14 54.4 0.0 3.4e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KXG49773.1 - 7.2e-11 41.8 10.1 1.7e-10 40.6 10.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXG49773.1 - 7.2e-10 38.6 13.8 8.6e-10 38.3 9.5 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXG49773.1 - 4.9e-09 35.9 10.7 4.9e-09 35.9 10.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXG49773.1 - 1.9e-08 34.5 9.9 1.9e-08 34.5 9.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KXG49773.1 - 4.8e-07 29.6 9.6 1.1e-06 28.5 9.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXG49773.1 - 6.4e-07 29.4 9.5 1.2e-06 28.5 9.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KXG49773.1 - 7.1e-07 29.2 6.2 1.7e-06 27.9 6.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXG49773.1 - 1.3e-05 24.9 8.3 1.3e-05 24.9 8.3 1.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KXG49773.1 - 5.6e-05 23.4 7.6 0.00016 21.9 7.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KXG49773.1 - 0.0013 18.5 6.5 0.0039 17.0 6.0 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KXG49773.1 - 0.048 13.8 6.4 0.13 12.4 6.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 U-box PF04564.15 KXG49773.1 - 0.05 13.8 0.1 0.74 10.0 0.0 2.7 3 0 0 3 3 3 0 U-box domain zf-RING_11 PF17123.5 KXG49773.1 - 0.15 11.8 3.8 0.48 10.2 3.8 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 KXG49773.1 - 0.22 11.4 7.7 0.48 10.3 7.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SNF2_N PF00176.23 KXG49774.1 - 1.6e-44 152.1 0.0 2.8e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXG49774.1 - 7.4e-17 61.7 0.3 1.4e-16 60.8 0.3 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXG49774.1 - 2.4e-08 33.5 0.0 4.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KXG49774.1 - 0.0002 21.4 0.0 0.00051 20.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SAM_2 PF07647.17 KXG49774.1 - 0.00093 19.3 0.0 0.009 16.1 0.0 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXG49774.1 - 0.0085 16.5 0.0 0.024 15.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KXG49774.1 - 0.069 13.4 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Thioredoxin_14 PF18402.1 KXG49774.1 - 0.07 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain SWI2_SNF2 PF18766.1 KXG49774.1 - 0.12 12.0 0.0 4.2 7.0 0.0 2.5 3 0 0 3 3 3 0 SWI2/SNF2 ATPase GSH_synth_ATP PF03917.17 KXG49775.1 - 5e-128 427.0 0.0 6e-128 426.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KXG49775.1 - 1.7e-29 102.3 0.1 2.8e-29 101.6 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase FMN_dh PF01070.18 KXG49776.1 - 4.6e-107 358.1 0.0 5.4e-107 357.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXG49776.1 - 2.2e-06 27.1 0.1 3.9e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXG49776.1 - 2.5e-06 26.8 0.2 0.00029 20.0 0.0 2.8 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXG49776.1 - 0.0064 15.9 0.9 0.0082 15.6 0.1 1.6 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 KXG49776.1 - 0.022 14.2 0.0 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KXG49776.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Bestrophin PF01062.21 KXG49777.1 - 1e-36 126.8 0.0 2e-36 125.9 0.0 1.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel T6SS_VasE PF05936.12 KXG49777.1 - 0.0099 14.6 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE RNase_P_Rpp14 PF01900.19 KXG49778.1 - 0.073 13.3 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Rpp14/Pop5 family Sugar_tr PF00083.24 KXG49779.1 - 1.8e-92 310.6 18.6 2.2e-92 310.3 18.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG49779.1 - 1.2e-12 47.4 44.0 7.2e-10 38.3 30.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_3 PF00202.21 KXG49781.1 - 2.9e-125 418.1 0.0 3.3e-125 417.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Spt4 PF06093.13 KXG49782.1 - 1.6e-32 111.4 0.3 1.9e-32 111.2 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger TackOD1 PF18551.1 KXG49782.1 - 0.041 13.6 1.3 0.053 13.2 1.3 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 PPP5 PF08321.12 KXG49783.1 - 1e-31 109.1 0.9 1.5e-31 108.5 0.1 1.7 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 KXG49783.1 - 1.2e-31 110.8 0.0 1.8e-31 110.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_2 PF07719.17 KXG49783.1 - 2.1e-09 36.8 3.8 0.062 13.4 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXG49783.1 - 2.5e-09 36.5 3.7 0.00021 21.0 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXG49783.1 - 4.5e-08 32.6 4.1 0.011 15.5 0.4 3.5 3 0 0 3 3 3 3 TPR repeat TPR_19 PF14559.6 KXG49783.1 - 2.5e-05 24.7 0.3 0.071 13.6 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXG49783.1 - 0.00017 21.7 0.1 0.12 12.6 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXG49783.1 - 0.0022 18.6 4.8 8.5 7.1 0.1 3.5 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXG49783.1 - 0.0026 17.8 0.7 1.7 9.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXG49783.1 - 0.035 14.5 3.0 4.8 7.8 0.1 4.1 4 1 1 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXG49783.1 - 0.044 13.8 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 KXG49783.1 - 0.21 12.5 3.4 7.3 7.7 0.3 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF89 PF01937.19 KXG49784.1 - 6e-137 456.3 0.1 6.9e-137 456.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Cytochrom_C550 PF14495.6 KXG49784.1 - 0.076 12.7 0.0 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c-550 domain Cut12 PF11500.8 KXG49785.1 - 3.4e-50 169.7 10.1 3.4e-50 169.7 10.1 4.4 3 1 1 4 4 4 1 Spindle pole body formation-associated protein Lebercilin PF15619.6 KXG49785.1 - 2.8 7.6 52.6 11 5.6 28.0 3.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF2730 PF10805.8 KXG49785.1 - 9 6.5 22.7 0.42 10.7 2.4 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF2730) DUF4267 PF14087.6 KXG49786.1 - 3.1e-31 107.7 3.7 3.8e-31 107.5 3.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) SecD_SecF PF02355.16 KXG49786.1 - 0.21 11.0 2.8 0.16 11.4 1.3 1.5 1 1 0 1 1 1 0 Protein export membrane protein Ost5 PF05251.12 KXG49786.1 - 7.1 7.0 10.0 1.2 9.4 0.6 3.0 2 1 1 3 3 3 0 Oligosaccharyltransferase subunit 5 HGTP_anticodon2 PF12745.7 KXG49787.1 - 5.8e-85 285.0 3.3 5.8e-85 285.0 3.3 1.9 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 KXG49787.1 - 3.9e-68 229.7 0.0 2.4e-37 128.7 0.0 4.0 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXG49787.1 - 7.3e-35 120.5 0.0 5.1e-19 68.6 0.0 3.7 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 KXG49787.1 - 7.3e-17 61.7 0.0 2.1e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 KXG49787.1 - 2.1e-12 46.9 2.2 1.5e-11 44.1 0.0 2.3 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.23 KXG49787.1 - 0.00015 21.8 3.3 0.00073 19.5 0.1 2.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KXG49787.1 - 0.0027 17.4 0.0 0.086 12.4 0.0 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 HGTP_anticodon PF03129.20 KXG49787.1 - 0.0028 17.8 0.1 0.0086 16.2 0.1 1.9 1 0 0 1 1 1 1 Anticodon binding domain HIF-1a_CTAD PF08778.10 KXG49787.1 - 0.078 12.6 0.3 0.35 10.5 0.0 2.2 2 0 0 2 2 2 0 HIF-1 alpha C terminal transactivation domain DUF1682 PF07946.14 KXG49787.1 - 0.1 11.8 5.2 0.18 11.0 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Torus PF16131.5 KXG49788.1 - 1.7e-16 60.8 0.1 1.6e-15 57.7 0.0 2.4 2 1 1 3 3 3 1 Torus domain RRM_1 PF00076.22 KXG49788.1 - 7.1e-08 32.2 0.0 1.4e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXG49788.1 - 0.0069 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KXG49788.1 - 0.14 12.4 0.9 1.4 9.1 0.0 2.4 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter MMR_HSR1_Xtn PF16897.5 KXG49789.1 - 6.4e-35 119.4 1.9 8.4e-34 115.8 0.2 2.3 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KXG49789.1 - 1.2e-20 73.7 0.0 3e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KXG49789.1 - 1e-18 67.1 0.1 2.3e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KXG49789.1 - 2.3e-12 46.7 0.0 3.9e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXG49789.1 - 6.5e-05 23.1 0.2 0.047 13.7 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 KXG49789.1 - 0.021 13.8 0.3 0.11 11.5 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 KXG49789.1 - 0.037 13.1 0.0 0.082 12.0 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain AIG1 PF04548.16 KXG49789.1 - 0.046 13.0 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family GATase PF00117.28 KXG49790.1 - 1.1e-45 155.7 0.0 1.6e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KXG49790.1 - 1.5e-45 154.2 0.0 3.1e-45 153.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 KXG49790.1 - 2.1e-05 24.4 0.2 0.00057 19.7 0.2 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KXG49790.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Zn_clus PF00172.18 KXG49792.1 - 3.2e-08 33.6 11.2 5.7e-08 32.8 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXG49792.1 - 6.3e-06 25.4 0.1 1.5e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain PIG-X PF08320.12 KXG49793.1 - 1.4e-67 227.7 0.0 2.7e-67 226.7 0.0 1.5 1 0 0 1 1 1 1 PIG-X / PBN1 DnaJ_C PF01556.18 KXG49793.1 - 8.9e-32 110.2 0.7 1.4e-31 109.6 0.7 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXG49793.1 - 1e-26 92.8 3.9 1.7e-26 92.1 3.9 1.4 1 0 0 1 1 1 1 DnaJ domain Peptidase_S10 PF00450.22 KXG49795.1 - 1.5e-53 182.7 0.1 3.1e-53 181.7 0.1 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase PARP PF00644.20 KXG49796.1 - 6.5e-33 114.0 0.4 4.6e-32 111.2 0.0 2.5 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain BRCT PF00533.26 KXG49796.1 - 4.7e-05 23.7 0.1 0.00013 22.3 0.1 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PARP_reg PF02877.14 KXG49796.1 - 0.00016 21.7 3.7 0.00017 21.7 2.2 1.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain PTCB-BRCT PF12738.7 KXG49796.1 - 0.00029 20.7 0.2 0.00063 19.6 0.2 1.5 1 0 0 1 1 1 1 twin BRCT domain PBP PF01161.20 KXG49797.1 - 1e-14 54.9 0.1 1.4e-14 54.6 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein p450 PF00067.22 KXG49798.1 - 2.6e-56 191.3 0.0 3.7e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Vg_Tdu PF07545.14 KXG49798.1 - 1.4 8.7 4.5 24 4.8 0.0 2.7 3 0 0 3 3 3 0 Vestigial/Tondu family Ysc84 PF04366.12 KXG49799.1 - 5.8e-47 158.6 0.0 8.9e-47 158.0 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator ETF PF01012.21 KXG49800.1 - 1.2e-43 149.1 0.3 1.5e-43 148.8 0.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ribosomal_L20 PF00453.18 KXG49800.1 - 0.024 14.7 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L20 Flavodoxin_1 PF00258.25 KXG49801.1 - 1.6e-31 109.4 0.0 2.8e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KXG49801.1 - 1.5e-29 103.2 0.0 2.2e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KXG49801.1 - 4.3e-15 56.3 0.0 1.3e-14 54.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 KXG49801.1 - 0.0081 15.9 0.0 0.026 14.2 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin domain Flavodoxin_5 PF12724.7 KXG49801.1 - 0.024 14.9 0.0 0.13 12.5 0.0 2.2 2 1 1 3 3 3 0 Flavodoxin domain RNA_pol_3_Rpc31 PF11705.8 KXG49802.1 - 1.4e-60 205.4 13.3 2.2e-60 204.7 13.3 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 MitMem_reg PF13012.6 KXG49803.1 - 1.7e-11 44.5 6.6 4.4e-11 43.2 6.6 1.7 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXG49803.1 - 2.1e-09 37.3 0.1 7.6e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Herpes_UL35 PF04496.12 KXG49803.1 - 0.078 13.3 0.2 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 Herpesvirus UL35 family Solute_trans_a PF03619.16 KXG49804.1 - 2.3e-91 306.0 22.8 2.7e-91 305.8 22.8 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4781 PF16013.5 KXG49804.1 - 0.027 13.3 0.8 0.041 12.7 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) DUF1129 PF06570.11 KXG49804.1 - 4.9 6.6 10.0 1.1 8.8 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) SAP PF02037.27 KXG49805.1 - 1.1e-09 37.9 0.2 2.1e-09 36.9 0.2 1.5 1 0 0 1 1 1 1 SAP domain RSB_motif PF16294.5 KXG49805.1 - 2.1e-06 27.9 0.1 2.1e-06 27.9 0.1 4.8 2 1 0 3 3 3 1 RNSP1-SAP18 binding (RSB) motif Glyoxalase_3 PF13468.6 KXG49805.1 - 0.82 9.8 5.3 0.15 12.2 1.0 1.9 2 0 0 2 2 2 0 Glyoxalase-like domain Glyco_hydro_67M PF07488.12 KXG49806.1 - 1.3e-146 487.9 0.0 1.9e-146 487.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 KXG49806.1 - 7.6e-90 300.3 3.1 1.2e-89 299.7 3.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 KXG49806.1 - 2.7e-35 121.3 0.0 5e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 KXG49806.1 - 0.003 18.3 0.0 0.0089 16.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 NAGLU_N PF12971.7 KXG49806.1 - 0.01 15.6 1.3 0.16 11.8 0.0 2.8 3 0 0 3 3 3 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Avidin PF01382.17 KXG49806.1 - 0.35 11.4 3.7 0.9 10.0 0.2 3.1 4 0 0 4 4 4 0 Avidin family Ribosomal_L7Ae PF01248.26 KXG49807.1 - 4e-25 87.4 0.0 4.5e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Abhydrolase_1 PF00561.20 KXG49808.1 - 1.5e-48 165.7 0.0 4.8e-48 164.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG49808.1 - 0.00019 22.1 4.1 0.00046 20.8 4.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family CBP_CCPA PF17040.5 KXG49808.1 - 0.043 14.4 0.1 3.5 8.3 0.0 2.9 2 1 0 2 2 2 0 Cellulose-complementing protein A Glyco_hydro_3_C PF01915.22 KXG49810.1 - 3.8e-60 203.3 0.0 6.5e-60 202.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXG49810.1 - 6.4e-50 170.3 0.0 1e-49 169.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXG49810.1 - 1.5e-23 82.7 1.4 1.4e-22 79.6 1.5 2.5 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KXG49810.1 - 4.8e-15 55.6 0.0 1e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 PA14 domain THOC2_N PF16134.5 KXG49811.1 - 2.8e-246 819.1 0.0 6.3e-246 817.9 0.0 1.6 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KXG49811.1 - 3.4e-106 354.8 0.0 5.5e-106 354.2 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KXG49811.1 - 3e-30 104.1 0.1 1.3e-29 102.0 0.0 2.2 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Epimerase PF01370.21 KXG49812.1 - 2.2e-09 37.2 0.0 0.00078 19.0 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXG49812.1 - 4e-07 30.5 0.0 7.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KXG49812.1 - 5.6e-07 29.4 0.0 8.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG49812.1 - 7.1e-07 29.3 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXG49812.1 - 0.00084 18.6 0.0 0.0012 18.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXG49812.1 - 0.14 11.2 0.0 0.44 9.5 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Vps5 PF09325.10 KXG49813.1 - 1e-14 54.7 0.9 1.7e-14 54.0 0.9 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KXG49813.1 - 9.8e-10 38.4 0.0 2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 PX domain KAsynt_C_assoc PF16197.5 KXG49813.1 - 0.076 13.5 0.5 0.16 12.4 0.5 1.5 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension GTP_EFTU PF00009.27 KXG49814.1 - 1.6e-54 184.4 0.0 2.5e-54 183.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KXG49814.1 - 9.2e-26 89.8 0.0 2.1e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KXG49814.1 - 5.8e-16 58.3 0.0 5.6e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXG49814.1 - 2.9e-06 27.6 0.0 6.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KXG49814.1 - 0.0022 17.8 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain DUF2383 PF09537.10 KXG49814.1 - 0.13 12.6 0.0 0.51 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) ArfGap PF01412.18 KXG49815.1 - 1.6e-30 105.5 0.1 3.8e-30 104.4 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.22 KXG49816.1 - 2.1e-32 110.7 0.2 2.8e-15 55.9 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXG49816.1 - 1.3e-05 25.2 0.0 0.015 15.4 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 KXG49816.1 - 0.00034 20.2 0.0 0.74 9.4 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KXG49816.1 - 0.0012 19.1 1.9 0.35 11.1 0.3 3.2 2 2 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 KXG49816.1 - 0.0042 16.9 0.1 5.7 6.9 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KXG49816.1 - 0.031 14.1 0.0 0.3 10.9 0.0 2.3 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain FXMRP1_C_core PF12235.8 KXG49816.1 - 0.21 12.2 10.4 0.52 11.0 10.4 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal DUF2985 PF11204.8 KXG49817.1 - 9.4e-23 80.2 2.7 2e-22 79.1 2.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) NAD_binding_10 PF13460.6 KXG49818.1 - 1.8e-06 28.0 0.0 0.00011 22.2 0.0 2.7 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXG49818.1 - 0.0036 16.9 0.1 0.0075 15.8 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family Hydrophobin PF01185.18 KXG49819.1 - 1.5e-08 35.1 7.1 2.1e-08 34.7 7.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin A2M PF00207.22 KXG49819.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Alpha-2-macroglobulin family SMI1_KNR4 PF09346.10 KXG49821.1 - 0.0062 16.9 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) MFS_1 PF07690.16 KXG49822.1 - 2.9e-36 125.1 33.8 5.6e-33 114.3 25.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXG49822.1 - 1.2e-05 24.0 18.9 0.00037 19.2 1.2 2.7 2 2 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 KXG49822.1 - 0.0027 16.1 7.4 0.032 12.5 4.1 2.5 1 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KXG49822.1 - 0.0037 16.2 19.7 0.0072 15.2 7.2 2.5 3 0 0 3 3 3 2 MFS_1 like family PAD_porph PF04371.15 KXG49823.1 - 8.1e-100 334.2 0.0 9.4e-100 334.0 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Orn_Arg_deC_N PF02784.16 KXG49824.1 - 5.9e-63 212.5 0.0 7.4e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KXG49824.1 - 2.4e-13 50.1 0.0 4.1e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 KXG49824.1 - 0.0056 16.3 0.0 0.0079 15.9 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain CinA PF02464.17 KXG49824.1 - 0.035 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Competence-damaged protein Opi1 PF08618.10 KXG49825.1 - 9.5e-47 160.2 11.1 2.2e-33 116.1 1.7 3.1 1 1 2 3 3 3 3 Transcription factor Opi1 RdRP PF05183.12 KXG49826.1 - 5.2e-133 444.8 0.0 6.8e-133 444.4 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase AA_permease PF00324.21 KXG49827.1 - 4.3e-76 256.4 30.0 5.3e-76 256.1 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG49827.1 - 8.5e-18 64.4 29.6 1e-17 64.1 29.6 1.1 1 0 0 1 1 1 1 Amino acid permease Stevor PF17410.2 KXG49827.1 - 8.1 5.9 5.3 1.2 8.6 1.2 1.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame NmrA PF05368.13 KXG49828.1 - 1.2e-26 93.8 0.0 1.5e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG49828.1 - 4e-16 59.4 0.0 5.8e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXG49828.1 - 2.8e-06 27.6 0.1 4.6e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KXG49828.1 - 0.0029 18.0 0.0 0.0049 17.3 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KXG49828.1 - 0.0038 17.2 0.1 0.0062 16.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXG49828.1 - 0.0071 15.8 0.0 0.031 13.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KXG49831.1 - 7.6e-54 182.7 3.2 1.8e-53 181.5 3.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG49831.1 - 1.9e-33 115.6 4.3 1.3e-32 112.9 4.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG49831.1 - 1.4e-07 31.6 3.6 5.1e-07 29.8 0.3 2.1 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KXG49831.1 - 0.00056 19.4 1.3 0.019 14.4 0.1 2.4 2 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KXG49831.1 - 0.0061 15.9 0.2 0.013 14.9 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXG49831.1 - 0.12 13.0 0.5 0.24 12.0 0.5 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Voldacs PF03517.13 KXG49833.1 - 1.3e-23 83.7 1.7 6.6e-23 81.4 0.6 2.4 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling Phe_tRNA-synt_N PF02912.18 KXG49834.1 - 0.4 10.7 1.7 0.63 10.0 1.7 1.2 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Pribosyltran PF00156.27 KXG49835.1 - 1.7e-22 79.6 0.0 3e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain P-mevalo_kinase PF04275.14 KXG49835.1 - 6.8e-18 64.7 0.0 1.6e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 Phosphomevalonate kinase FAD_binding_4 PF01565.23 KXG49835.1 - 2.3e-05 24.2 0.4 5.8e-05 22.9 0.4 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG49835.1 - 0.00029 20.8 0.0 0.00063 19.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like UPRTase PF14681.6 KXG49835.1 - 0.00046 19.7 0.1 0.0011 18.4 0.1 1.6 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Methyltransf_23 PF13489.6 KXG49835.1 - 0.032 14.1 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PRTase_2 PF15609.6 KXG49835.1 - 0.043 13.3 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosyl transferase Sigma54_activat PF00158.26 KXG49835.1 - 0.18 11.5 0.0 0.42 10.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Acetyltransf_1 PF00583.25 KXG49836.1 - 6.3e-08 32.9 0.0 7.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXG49836.1 - 2.7e-06 27.7 0.0 3.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG49836.1 - 1.1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KXG49836.1 - 1.8e-05 24.7 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXG49836.1 - 0.0074 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KXG49836.1 - 0.034 14.8 0.0 0.055 14.1 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Beta-lactamase PF00144.24 KXG49837.1 - 2.3e-44 152.0 0.0 7.4e-44 150.3 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase FMO-like PF00743.19 KXG49838.1 - 8.9e-22 77.2 0.2 6.7e-18 64.4 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXG49838.1 - 1.3e-13 50.9 0.0 2.3e-11 43.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG49838.1 - 4.5e-10 39.2 0.0 2.6e-09 36.7 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXG49838.1 - 2.2e-09 37.0 0.0 1.6e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG49838.1 - 1.3e-07 31.8 0.0 3.1e-06 27.3 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXG49838.1 - 0.00022 21.2 1.4 7.6 6.5 0.0 4.3 4 0 0 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXG49838.1 - 0.00068 18.8 0.0 0.012 14.6 0.0 2.6 3 1 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.24 KXG49838.1 - 0.0028 17.3 0.6 0.17 11.4 0.0 2.8 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXG49838.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KXG49838.1 - 0.014 15.9 0.1 0.98 10.0 0.2 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG49838.1 - 0.016 14.5 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KXG49838.1 - 0.055 12.2 0.9 0.19 10.4 0.1 2.2 3 0 0 3 3 3 0 HI0933-like protein ThiF PF00899.21 KXG49838.1 - 0.17 11.2 0.0 50 3.1 0.0 3.0 3 0 0 3 3 3 0 ThiF family MFS_1 PF07690.16 KXG49839.1 - 3.3e-34 118.4 53.7 9.2e-33 113.6 51.1 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG49839.1 - 1.8e-19 69.6 28.1 2.8e-19 69.0 27.5 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXG49839.1 - 2.7e-12 46.3 6.0 2.7e-12 46.3 6.0 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KXG49839.1 - 0.15 10.4 10.4 0.064 11.5 3.4 3.0 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Metallophos PF00149.28 KXG49840.1 - 9.2e-37 127.5 0.0 1.5e-36 126.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1996 PF09362.10 KXG49841.1 - 1.9e-83 280.0 1.4 3.3e-83 279.3 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) zf-C3Hc3H PF13891.6 KXG49841.1 - 0.13 12.7 1.1 0.3 11.5 1.1 1.7 1 0 0 1 1 1 0 Potential DNA-binding domain Aldo_ket_red PF00248.21 KXG49842.1 - 3.5e-71 239.8 0.0 4.2e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_ABA_S PF18066.1 KXG49842.1 - 0.038 14.7 0.1 0.19 12.4 0.0 2.1 2 0 0 2 2 2 0 Phage ABA sandwich domain adh_short_C2 PF13561.6 KXG49844.1 - 1.4e-61 208.1 0.0 2.1e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG49844.1 - 2.3e-50 170.8 0.1 3.4e-50 170.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DIOX_N PF14226.6 KXG49844.1 - 5.9e-31 107.7 0.0 2.1e-30 105.9 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG49844.1 - 1.8e-13 50.8 0.0 4.4e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily KR PF08659.10 KXG49844.1 - 7.6e-05 22.7 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 KR domain HI0933_like PF03486.14 KXG49844.1 - 0.057 12.1 0.1 0.08 11.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Epimerase PF01370.21 KXG49844.1 - 0.072 12.5 0.1 0.18 11.2 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CM_2 PF01817.21 KXG49845.1 - 9.3e-13 48.3 0.1 1.1e-12 48.0 0.1 1.1 1 0 0 1 1 1 1 Chorismate mutase type II Nucleic_acid_bd PF13820.6 KXG49845.1 - 0.033 14.0 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative nucleic acid-binding region Osmo_CC PF08946.10 KXG49845.1 - 0.042 14.1 0.3 0.069 13.4 0.3 1.2 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Fungal_trans_2 PF11951.8 KXG49846.1 - 5e-38 130.9 0.2 6.5e-38 130.5 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG49846.1 - 3.6e-08 33.4 9.3 7.1e-08 32.4 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fmp27_GFWDK PF10347.9 KXG49846.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain PNTB PF02233.16 KXG49847.1 - 4.5e-171 569.8 23.7 4.5e-171 569.8 23.7 2.6 4 0 0 4 4 4 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KXG49847.1 - 1.5e-74 249.9 0.1 5.7e-74 248.0 0.1 2.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KXG49847.1 - 4.5e-44 150.0 0.0 9.8e-44 149.0 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AA_permease_2 PF13520.6 KXG49847.1 - 1.2e-43 149.6 50.0 1.2e-43 149.6 50.0 2.9 2 1 0 2 2 1 1 Amino acid permease PNTB_4TM PF12769.7 KXG49847.1 - 6.2e-30 103.5 3.6 6.2e-30 103.5 3.6 5.6 5 1 0 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch AA_permease PF00324.21 KXG49847.1 - 1.3e-15 57.0 38.7 1.3e-15 57.0 38.7 2.5 2 1 0 2 2 1 1 Amino acid permease 2-Hacid_dh_C PF02826.19 KXG49847.1 - 8.3e-05 22.0 0.1 0.22 10.9 0.0 3.2 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 KXG49847.1 - 0.0045 16.7 0.8 0.018 14.8 0.2 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N PF00107.26 KXG49847.1 - 0.033 14.2 0.1 0.18 11.8 0.1 2.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KXG49847.1 - 0.044 13.0 0.1 0.093 11.9 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXG49847.1 - 0.19 10.8 0.6 0.3 10.1 0.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ELO PF01151.18 KXG49849.1 - 2.7e-61 207.3 23.5 3.1e-61 207.1 23.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family COX5A PF02284.16 KXG49850.1 - 1.8e-37 127.5 0.2 2.5e-37 127.0 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Glyco_transf_15 PF01793.16 KXG49851.1 - 1.4e-112 376.1 5.2 1.7e-112 375.9 5.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_25 PF01755.17 KXG49851.1 - 0.036 13.9 0.3 0.053 13.4 0.3 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) GCP_N_terminal PF17681.1 KXG49852.1 - 2.4e-32 112.8 2.3 2.4e-32 112.8 2.3 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXG49852.1 - 8.4e-22 78.0 3.4 1.6e-21 77.1 3.4 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 KXG49852.1 - 6.1e-14 51.3 0.0 1.6e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 tRNA-synt_1b PF00579.25 KXG49853.1 - 1.4e-49 169.0 0.0 2e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) GATase_5 PF13507.6 KXG49854.1 - 1.9e-97 325.4 0.0 2.8e-97 324.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KXG49854.1 - 9e-38 129.8 0.2 2.2e-24 86.3 0.2 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KXG49854.1 - 2.7e-32 111.2 0.0 5.6e-32 110.1 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KXG49854.1 - 3.6e-22 78.7 0.0 8.2e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 KXG49854.1 - 0.064 13.9 0.2 0.35 11.6 0.0 2.3 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain LEA_3 PF03242.13 KXG49854.1 - 0.12 13.1 0.1 0.43 11.3 0.1 1.9 1 0 0 1 1 1 0 Late embryogenesis abundant protein MFS_1 PF07690.16 KXG49855.1 - 4e-44 151.0 29.1 4e-44 151.0 29.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG49855.1 - 5.1e-09 35.1 1.9 8.9e-09 34.3 1.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXG49855.1 - 3.9e-06 26.0 28.6 2.3e-05 23.5 28.6 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KXG49855.1 - 0.00091 18.6 2.4 0.00091 18.6 2.4 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2178 PF09946.9 KXG49855.1 - 3.2 8.0 7.0 9.4 6.5 0.4 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2178) OATP PF03137.20 KXG49855.1 - 6.3 4.9 12.0 0.15 10.3 1.3 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TOM13 PF08219.11 KXG49856.1 - 2.5e-37 126.7 0.1 3.2e-37 126.4 0.1 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.20 KXG49857.1 - 7e-23 81.3 0.3 1.3e-22 80.5 0.3 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein DUF3523 PF12037.8 KXG49857.1 - 0.017 14.5 8.2 0.036 13.5 8.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Acyl_transf_3 PF01757.22 KXG49858.1 - 5.7e-20 71.7 20.5 1e-19 70.8 20.5 1.4 1 1 0 1 1 1 1 Acyltransferase family TAFII28 PF04719.14 KXG49859.1 - 3.2e-25 88.0 1.9 7.9e-24 83.6 0.2 2.2 2 0 0 2 2 2 2 hTAFII28-like protein conserved region Baseplate_J PF04865.14 KXG49859.1 - 0.0094 15.1 0.6 0.014 14.6 0.6 1.2 1 0 0 1 1 1 1 Baseplate J-like protein Med3 PF11593.8 KXG49859.1 - 4.8 6.3 13.4 7.1 5.7 13.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SAM_decarbox PF01536.16 KXG49860.1 - 2.2e-132 441.4 0.0 2.6e-132 441.1 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TAF6_C PF07571.13 KXG49861.1 - 3.7e-30 104.1 0.0 9.1e-30 102.8 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KXG49861.1 - 3.7e-24 84.7 0.1 2e-23 82.3 0.1 2.1 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KXG49861.1 - 5.6e-06 26.8 0.4 2.3e-05 24.7 0.3 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXG49861.1 - 0.0051 16.9 0.1 0.013 15.6 0.1 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 KXG49861.1 - 0.048 13.9 0.9 0.11 12.7 0.1 2.0 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CRAL_TRIO PF00650.20 KXG49862.1 - 2.9e-16 59.6 0.0 4.5e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXG49862.1 - 9.3e-09 35.4 0.0 2e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Prok_Ub PF14454.6 KXG49862.1 - 0.082 12.6 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 Prokaryotic Ubiquitin MFS_1 PF07690.16 KXG49863.1 - 1.2e-32 113.3 36.2 1.1e-29 103.5 27.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG49863.1 - 0.00034 19.6 2.3 0.00034 19.6 2.3 2.8 2 1 1 3 3 3 2 MFS_1 like family MFS_3 PF05977.13 KXG49863.1 - 0.00041 18.9 1.8 0.00041 18.9 1.8 2.9 3 0 0 3 3 3 1 Transmembrane secretion effector FPN1 PF06963.12 KXG49863.1 - 0.012 14.2 3.1 1.5 7.3 3.1 2.4 1 1 0 1 1 1 0 Ferroportin1 (FPN1) IPP-2 PF04979.14 KXG49864.1 - 1.5e-19 71.0 15.9 1.5e-19 71.0 15.9 2.4 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) DUF3410 PF11890.8 KXG49864.1 - 0.033 14.0 0.3 9.4 6.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) CAF1A PF12253.8 KXG49865.1 - 2.5e-19 69.2 8.3 2.5e-19 69.2 8.3 4.0 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.8 KXG49865.1 - 0.29 10.8 74.5 0.034 13.9 69.7 1.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SRP-alpha_N PF04086.13 KXG49865.1 - 1.8 8.4 34.7 5.2 6.9 34.7 1.8 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Asp-B-Hydro_N PF05279.11 KXG49865.1 - 2.5 8.1 40.2 5.5 7.0 40.2 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Mitofilin PF09731.9 KXG49865.1 - 6.9 5.4 38.8 11 4.7 38.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Peroxin-3 PF04882.12 KXG49867.1 - 1.1e-172 575.3 0.4 1.4e-172 575.0 0.4 1.1 1 0 0 1 1 1 1 Peroxin-3 ATG101 PF07855.12 KXG49868.1 - 7e-53 178.8 0.0 8e-53 178.6 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Kdo PF06293.14 KXG49869.1 - 0.00016 21.1 0.4 0.00024 20.5 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXG49869.1 - 0.0011 19.0 0.3 0.0028 17.6 0.3 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXG49869.1 - 0.0016 18.1 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KXG49869.1 - 0.01 15.2 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_fungal PF17667.1 KXG49869.1 - 0.029 13.2 0.3 0.04 12.7 0.3 1.1 1 0 0 1 1 1 0 Fungal protein kinase WaaY PF06176.11 KXG49869.1 - 0.044 13.4 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) TB2_DP1_HVA22 PF03134.19 KXG49870.1 - 1.4e-23 82.6 8.3 1.4e-23 82.6 8.3 1.7 1 1 1 2 2 2 2 TB2/DP1, HVA22 family Ras PF00071.22 KXG49871.1 - 7.2e-44 149.2 0.0 9.3e-44 148.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXG49871.1 - 1.2e-11 44.9 0.0 1.7e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG49871.1 - 1e-05 25.1 0.0 1.3e-05 24.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXG49871.1 - 6.2e-05 22.6 0.0 8.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Carboxyl_trans PF01039.22 KXG49872.1 - 1.3e-137 459.4 0.1 1.6e-137 459.1 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Acyl-CoA_dh_1 PF00441.24 KXG49873.1 - 2.5e-40 138.1 1.8 4e-40 137.5 1.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXG49873.1 - 1.8e-33 115.6 0.1 3.6e-33 114.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXG49873.1 - 4.7e-27 94.0 0.1 9.9e-27 93.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXG49873.1 - 4.3e-15 56.2 0.3 6.8e-15 55.5 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KXG49873.1 - 0.00095 18.9 0.0 0.0037 17.0 0.0 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal p450 PF00067.22 KXG49876.1 - 5e-66 223.3 0.0 5.9e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CPSase_L_D2 PF02786.17 KXG49877.1 - 2.2e-73 246.3 0.0 4.4e-73 245.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KXG49877.1 - 3.6e-37 126.8 0.0 1e-36 125.3 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KXG49877.1 - 1.7e-32 112.2 0.0 4e-32 111.0 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KXG49877.1 - 1.2e-17 63.5 0.7 5.4e-17 61.4 0.5 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KXG49877.1 - 2e-09 37.3 0.0 4.6e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KXG49877.1 - 6.2e-07 29.1 0.3 0.028 14.2 0.1 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 KXG49877.1 - 4.1e-05 23.7 0.0 9.3e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KXG49877.1 - 0.0018 18.1 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.6 KXG49877.1 - 0.0027 18.4 0.1 3.2 8.5 0.0 2.9 2 0 0 2 2 2 2 HlyD family secretion protein ATPgrasp_ST PF14397.6 KXG49877.1 - 0.0063 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 KXG49877.1 - 0.033 14.1 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein adh_short_C2 PF13561.6 KXG49879.1 - 3.5e-55 187.1 0.1 4.7e-55 186.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG49879.1 - 7.9e-39 133.1 0.1 1.1e-38 132.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG49879.1 - 7.8e-12 45.5 0.1 1.2e-11 44.9 0.1 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXG49879.1 - 0.095 12.1 0.0 6.8 6.0 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase AMP-binding PF00501.28 KXG49880.1 - 3e-59 200.7 0.0 3.8e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KXG49880.1 - 0.0034 16.1 0.0 0.0075 15.0 0.0 1.5 1 1 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 KXG49880.1 - 0.0062 17.5 0.0 0.018 16.0 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain F-box-like PF12937.7 KXG49881.1 - 1.1e-06 28.5 0.4 3.7e-06 26.7 0.1 2.1 2 0 0 2 2 2 1 F-box-like DUF1752 PF08550.10 KXG49882.1 - 0.011 15.5 0.5 0.027 14.3 0.5 1.7 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) MARVEL PF01284.23 KXG49883.1 - 6.9e-07 29.4 4.0 6.9e-07 29.4 4.0 1.7 2 1 0 2 2 2 1 Membrane-associating domain VIT1 PF01988.19 KXG49883.1 - 0.0076 16.1 0.1 0.008 16.1 0.1 1.2 1 0 0 1 1 1 1 VIT family DUF1195 PF06708.11 KXG49883.1 - 0.045 13.5 0.1 0.076 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) PHD PF00628.29 KXG49885.1 - 3.9e-09 36.3 1.8 8.7e-09 35.2 1.8 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXG49885.1 - 0.019 14.5 1.8 0.03 13.9 1.8 1.3 1 0 0 1 1 1 0 PHD-finger eIF-5a PF01287.20 KXG49886.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Peptidase_M28 PF04389.17 KXG49887.1 - 1.9e-38 132.1 0.1 3.4e-38 131.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXG49887.1 - 1.6e-11 44.0 2.5 4.7e-11 42.6 2.5 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KXG49887.1 - 7.5e-05 22.5 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KXG49887.1 - 0.039 13.0 0.0 0.6 9.1 0.0 2.3 2 1 0 2 2 2 0 M42 glutamyl aminopeptidase Nicastrin PF05450.15 KXG49887.1 - 0.053 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Nicastrin DUF4628 PF15429.6 KXG49887.1 - 0.075 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) Abhydrolase_1 PF00561.20 KXG49888.1 - 2e-15 57.1 0.2 3e-15 56.6 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG49888.1 - 2.6e-11 44.6 12.5 5.9e-10 40.1 12.5 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG49888.1 - 2.4e-10 40.1 0.0 3.8e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KXG49888.1 - 0.0032 17.1 0.2 0.0086 15.7 0.2 1.7 1 1 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KXG49888.1 - 0.032 13.1 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase_phd PF10503.9 KXG49888.1 - 0.044 13.3 0.5 0.086 12.3 0.5 1.6 1 0 0 1 1 1 0 Esterase PHB depolymerase NTP_transf_5 PF14907.6 KXG49890.1 - 0.005 16.5 0.0 0.011 15.4 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised nucleotidyltransferase AbiEii PF08843.11 KXG49890.1 - 0.017 15.1 0.0 0.038 13.9 0.0 1.5 1 1 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system SRR1 PF07985.12 KXG49892.1 - 1.5e-17 63.4 0.1 3.7e-17 62.1 0.1 1.7 2 0 0 2 2 2 1 SRR1 RRP7 PF12923.7 KXG49892.1 - 0.0081 16.3 0.2 0.02 15.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Glyco_hydro_17 PF00332.18 KXG49893.1 - 5.7e-10 39.3 5.6 2.7e-06 27.2 0.9 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Rick_17kDa_Anti PF05433.15 KXG49893.1 - 0.023 14.6 1.4 0.023 14.6 1.4 2.9 2 0 0 2 2 2 0 Glycine zipper 2TM domain ISPD_C PF18706.1 KXG49893.1 - 0.17 11.5 0.1 0.24 11.0 0.1 1.2 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain Gram_pos_anchor PF00746.21 KXG49893.1 - 0.86 9.6 3.6 6.3 6.8 0.7 2.5 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF1269 PF06897.12 KXG49893.1 - 1.1 9.6 5.6 2.8 8.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) DHHC PF01529.20 KXG49896.1 - 6.3e-27 94.3 6.8 6.3e-27 94.3 6.8 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase zf-C3H1 PF10650.9 KXG49898.1 - 1.7e-13 50.0 0.5 2.7e-13 49.4 0.5 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain E1_dh PF00676.20 KXG49898.1 - 0.24 10.3 0.7 0.52 9.2 0.7 1.5 1 0 0 1 1 1 0 Dehydrogenase E1 component Myosin_head PF00063.21 KXG49899.1 - 5.1e-265 880.9 0.0 1.5e-264 879.4 0.0 1.9 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KXG49899.1 - 2.7e-15 55.4 277.1 1.1e-11 43.4 194.1 5.8 1 1 1 2 2 2 2 Myosin tail Myosin_N PF02736.19 KXG49899.1 - 2.4e-08 33.7 0.0 6.7e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KXG49899.1 - 0.15 12.3 0.0 0.15 12.3 0.0 4.7 5 0 0 5 5 5 0 AAA domain Isy1 PF06246.12 KXG49900.1 - 5.1e-76 255.6 0.3 5.9e-76 255.4 0.3 1.0 1 0 0 1 1 1 1 Isy1-like splicing family MMR_HSR1 PF01926.23 KXG49901.1 - 1.3e-15 57.4 0.0 3.1e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXG49901.1 - 3.9e-08 33.4 0.3 9.4e-08 32.1 0.3 1.6 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KXG49901.1 - 1.6e-06 27.7 0.1 2.6e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 KXG49901.1 - 9.6e-06 25.1 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 KXG49901.1 - 0.00028 20.3 0.0 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 KXG49901.1 - 0.0026 17.3 0.0 0.01 15.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KXG49901.1 - 0.01 16.4 0.1 0.022 15.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXG49901.1 - 0.016 15.6 0.0 0.032 14.6 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain Dynamin_N PF00350.23 KXG49901.1 - 0.017 15.2 0.1 0.52 10.3 0.1 2.4 1 1 1 2 2 2 0 Dynamin family SRPRB PF09439.10 KXG49901.1 - 0.018 14.5 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KXG49901.1 - 0.025 14.0 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 KXG49901.1 - 0.039 14.2 0.1 0.081 13.1 0.1 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG49901.1 - 0.039 13.4 0.0 0.38 10.2 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family G-alpha PF00503.20 KXG49901.1 - 0.089 11.9 0.0 0.26 10.4 0.0 1.5 1 1 0 1 1 1 0 G-protein alpha subunit NB-ARC PF00931.22 KXG49901.1 - 0.11 11.6 0.1 0.23 10.6 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain IIGP PF05049.13 KXG49901.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PI3Ka PF00613.20 KXG49902.1 - 1.1e-57 194.4 0.4 1.8e-57 193.7 0.4 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KXG49902.1 - 1.1e-43 149.8 0.0 1e-30 107.4 0.0 2.7 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KXG49902.1 - 2.5e-29 102.0 0.0 4.1e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.10 KXG49903.1 - 4.7e-33 113.3 0.9 1.1e-32 112.1 0.0 2.2 3 0 0 3 3 3 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KXG49903.1 - 2.4e-16 59.6 0.1 7.3e-16 58.0 0.1 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE tify PF06200.14 KXG49903.1 - 0.091 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 tify domain DUF4336 PF14234.6 KXG49904.1 - 2e-18 66.7 0.0 6e-14 52.0 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) MARVEL PF01284.23 KXG49905.1 - 3.3e-20 72.6 11.0 4.2e-20 72.3 11.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain LCCL PF03815.19 KXG49907.1 - 5.1e-22 77.8 0.0 8.5e-22 77.1 0.0 1.3 1 0 0 1 1 1 1 LCCL domain ThiF PF00899.21 KXG49908.1 - 1.4e-40 139.2 0.0 2.5e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 ThiF family Metallophos PF00149.28 KXG49908.1 - 2.7e-11 44.3 0.0 1.9e-10 41.6 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXG49908.1 - 2.8e-06 27.6 0.0 6.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sacchrp_dh_NADP PF03435.18 KXG49908.1 - 0.0057 16.9 0.1 0.18 12.1 0.1 2.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KXG49908.1 - 0.0079 16.4 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KXG49908.1 - 0.032 13.8 0.1 0.06 12.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Metallophos_3 PF14582.6 KXG49908.1 - 0.033 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily ApbA PF02558.16 KXG49908.1 - 0.04 13.6 0.1 0.078 12.6 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Melibiase_2 PF16499.5 KXG49908.1 - 0.052 12.7 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha galactosidase A NACHT PF05729.12 KXG49909.1 - 4.7e-07 29.9 0.0 1.3e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain SesA PF17107.5 KXG49909.1 - 2.9e-05 24.3 0.3 0.00011 22.4 0.0 2.1 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_16 PF13191.6 KXG49909.1 - 0.0011 19.3 0.1 0.0081 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KXG49909.1 - 0.023 15.2 0.6 0.61 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXG49909.1 - 0.025 14.8 0.1 0.14 12.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain SHE3 PF17078.5 KXG49909.1 - 0.028 14.1 1.4 0.062 13.0 1.4 1.5 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 NB-ARC PF00931.22 KXG49909.1 - 0.043 13.0 0.2 0.096 11.9 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 KXG49909.1 - 0.051 14.1 0.0 0.17 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXG49909.1 - 0.072 13.6 0.9 0.18 12.3 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 KXG49909.1 - 0.083 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXG49909.1 - 0.093 12.5 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Baculo_PEP_C PF04513.12 KXG49909.1 - 8.8 6.4 7.3 3.4 7.7 0.8 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mac PF12464.8 KXG49910.1 - 3.1e-11 43.3 0.2 4.8e-11 42.7 0.2 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 KXG49910.1 - 8.4e-11 41.4 5.0 2.8e-08 33.3 1.8 2.6 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KXG49910.1 - 1.9e-09 36.9 6.9 1e-07 31.4 3.3 2.9 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Abhydrolase_1 PF00561.20 KXG49911.1 - 3.2e-47 161.3 0.0 9.6e-47 159.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXG49911.1 - 0.00046 19.9 0.2 0.00091 18.9 0.0 1.5 2 0 0 2 2 2 1 Putative esterase Gly_transf_sug PF04488.15 KXG49912.1 - 1.3e-12 48.2 0.0 2.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif FAD_binding_4 PF01565.23 KXG49913.1 - 3.7e-23 81.8 1.0 6.9e-23 80.9 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG49913.1 - 2.7e-12 46.6 1.5 5.4e-12 45.6 1.5 1.5 1 0 0 1 1 1 1 Berberine and berberine like Pkinase PF00069.25 KXG49914.1 - 4.5e-62 209.8 0.0 5.8e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG49914.1 - 9.3e-37 126.7 0.0 1.3e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXG49914.1 - 1.3e-05 24.3 0.1 1.8e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXG49914.1 - 0.014 14.7 0.0 0.021 14.2 0.0 1.4 1 1 0 1 1 1 0 Kinase-like FTA2 PF13095.6 KXG49914.1 - 0.026 14.1 0.1 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KXG49914.1 - 0.034 12.9 0.0 0.074 11.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KXG49914.1 - 0.04 13.8 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KXG49914.1 - 0.087 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ATP-synt_C PF00137.21 KXG49915.1 - 3.8e-25 88.0 35.4 4.7e-17 62.1 13.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CNH PF00780.22 KXG49916.1 - 8.3e-81 271.6 0.0 1.9e-80 270.4 0.0 1.6 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 KXG49916.1 - 2.7e-44 150.6 0.0 5.7e-44 149.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KXG49916.1 - 8.7e-37 127.1 0.0 1.8e-36 126.1 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KXG49916.1 - 5.4e-13 48.8 0.0 1.3e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Septin PF00735.18 KXG49917.1 - 1.2e-89 300.3 0.5 3.4e-89 298.9 0.0 1.9 2 1 0 2 2 2 1 Septin AAA_22 PF13401.6 KXG49917.1 - 0.0039 17.5 0.0 0.012 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXG49917.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXG49917.1 - 0.012 15.5 0.8 0.091 12.7 0.0 2.4 3 0 0 3 3 3 0 RsgA GTPase IIGP PF05049.13 KXG49917.1 - 0.053 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 KXG49917.1 - 0.084 13.4 0.7 0.87 10.1 0.0 2.5 2 1 0 2 2 2 0 ABC transporter EB1 PF03271.17 KXG49917.1 - 0.12 12.6 2.6 2.7 8.3 0.9 2.6 2 0 0 2 2 2 0 EB1-like C-terminal motif MMR_HSR1 PF01926.23 KXG49917.1 - 0.16 12.0 0.0 0.43 10.7 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase WD40 PF00400.32 KXG49918.1 - 8.5e-07 29.6 0.7 0.094 13.6 0.0 3.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG49918.1 - 9.5e-05 22.6 0.0 0.011 16.0 0.0 3.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KXG49918.1 - 0.0045 16.4 0.0 0.096 12.0 0.0 2.2 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KXG49918.1 - 0.047 12.6 0.0 1.1 8.2 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KXG49918.1 - 0.26 9.5 0.0 0.41 8.9 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz RRM_1 PF00076.22 KXG49919.1 - 4.4e-20 71.3 0.1 1.6e-19 69.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXG49919.1 - 8e-06 25.9 0.0 2.2e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif OB_RNB PF08206.11 KXG49919.1 - 0.11 12.2 0.1 0.73 9.6 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_5 PF13893.6 KXG49919.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DLIC PF05783.11 KXG49920.1 - 1e-36 126.8 0.0 2.9e-35 122.0 0.0 2.4 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) Spermine_synth PF01564.17 KXG49921.1 - 5.4e-08 32.5 0.0 9.8e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain DUF2052 PF09747.9 KXG49922.1 - 1.5e-22 80.7 15.6 1.8e-11 44.5 0.3 2.1 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) AMP-binding PF00501.28 KXG49923.1 - 1.3e-96 323.8 0.0 1.6e-96 323.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG49923.1 - 1.8e-18 67.3 0.1 4e-18 66.2 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.25 KXG49924.1 - 4e-20 72.1 0.0 1.8e-17 63.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXG49924.1 - 4.7e-08 32.9 0.0 1.9e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KXG49924.1 - 0.0077 15.4 0.0 0.0093 15.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein SET PF00856.28 KXG49925.1 - 2.4e-10 41.1 0.6 1.8e-09 38.2 0.0 2.2 2 1 0 2 2 2 1 SET domain HC2 PF07382.11 KXG49925.1 - 0.00091 19.4 14.1 0.0013 18.8 14.1 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 UBA_4 PF14555.6 KXG49926.1 - 1.1e-11 44.3 2.1 4.8e-11 42.3 0.2 2.9 3 0 0 3 3 3 1 UBA-like domain UIM PF02809.20 KXG49926.1 - 0.093 12.7 1.8 0.37 10.8 1.8 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif Dynactin_p22 PF07426.11 KXG49927.1 - 2.6e-10 40.4 0.0 3.7e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 Dynamitin PF04912.14 KXG49927.1 - 0.055 12.8 0.3 0.25 10.6 0.0 1.9 2 0 0 2 2 2 0 Dynamitin SH3_1 PF00018.28 KXG49929.1 - 9.9e-09 34.7 0.1 1.9e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXG49929.1 - 2.4e-06 27.1 0.0 5.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KXG49929.1 - 1.1e-05 25.1 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF4203 PF13886.6 KXG49929.1 - 0.011 15.4 11.2 0.016 14.9 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) TMEM220 PF15071.6 KXG49929.1 - 0.24 12.2 2.1 0.45 11.3 1.8 1.6 1 1 0 1 1 1 0 Transmembrane family 220, helix MFS_1 PF07690.16 KXG49930.1 - 7.1e-44 150.2 42.1 7.1e-44 150.2 42.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG49930.1 - 6.4e-17 61.5 12.6 6.4e-17 61.5 12.6 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 KXG49930.1 - 0.0054 15.6 9.4 0.0054 15.6 9.4 3.3 2 2 1 3 3 3 2 MFS_1 like family Cys_Met_Meta_PP PF01053.20 KXG49931.1 - 4.6e-34 117.6 0.0 6e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Cu-oxidase_3 PF07732.15 KXG49932.1 - 1.3e-37 128.5 2.5 1.3e-37 128.5 2.5 2.4 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXG49932.1 - 2.9e-36 124.2 1.7 2.9e-36 124.2 1.7 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KXG49932.1 - 9.7e-29 100.5 1.9 4.4e-22 78.9 0.1 3.5 3 1 1 4 4 4 2 Multicopper oxidase Response_reg PF00072.24 KXG49934.1 - 4.5e-20 71.9 0.0 1.4e-13 50.9 0.0 2.2 2 0 0 2 2 2 2 Response regulator receiver domain Bot1p PF12298.8 KXG49935.1 - 2.6e-51 174.2 0.1 2.6e-51 174.2 0.1 1.6 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein RRM_1 PF00076.22 KXG49936.1 - 9.1e-17 60.6 0.0 2.7e-14 52.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXG49936.1 - 0.052 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Ribosomal_S16 PF00886.19 KXG49937.1 - 9.1e-25 86.5 0.1 1.4e-24 85.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.15 KXG49938.1 - 1.1e-23 84.0 0.0 2.2e-23 83.0 0.0 1.4 1 1 1 2 2 2 1 YjeF-related protein N-terminus Nup35_RRM_2 PF14605.6 KXG49938.1 - 0.023 14.7 0.0 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PUL PF08324.11 KXG49939.1 - 1.2e-75 254.4 0.6 1.7e-75 253.8 0.6 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KXG49939.1 - 2.6e-45 153.3 0.1 4.4e-45 152.6 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KXG49939.1 - 4.5e-26 90.6 6.5 1e-07 32.5 1.2 7.1 6 1 0 6 6 6 5 WD domain, G-beta repeat BBS2_Mid PF14783.6 KXG49939.1 - 0.066 13.3 0.3 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 KXG49940.1 - 8e-22 77.1 10.6 3.1e-07 31.0 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG49940.1 - 1.6e-07 31.5 0.2 0.15 12.4 0.0 4.5 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXG49940.1 - 0.0011 18.0 0.2 0.2 10.6 0.0 2.6 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 KXG49940.1 - 0.0021 17.0 0.0 0.13 11.1 0.0 2.1 2 0 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) Cytochrom_D1 PF02239.16 KXG49940.1 - 0.0068 15.0 0.0 0.012 14.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain dsrm PF00035.26 KXG49940.1 - 0.11 13.2 0.0 0.3 11.8 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif RRM_1 PF00076.22 KXG49941.1 - 1.3e-15 57.0 0.0 2.1e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KXG49941.1 - 3.6e-08 33.8 33.9 1.9e-07 31.5 9.5 4.3 4 0 0 4 4 4 3 C-terminal duplication domain of Friend of PRMT1 CH PF00307.31 KXG49942.1 - 4.2e-46 155.6 0.0 9.3e-22 77.3 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KXG49942.1 - 1.6e-26 92.2 0.1 4.3e-26 90.8 0.1 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KXG49942.1 - 2.1e-09 37.1 0.4 2.5e-05 24.0 0.1 2.8 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 KXG49942.1 - 0.00027 20.6 0.1 0.0017 18.2 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KXG49942.1 - 0.0019 17.6 0.1 0.024 14.2 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KXG49942.1 - 0.016 15.0 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair FliG_N PF14842.6 KXG49942.1 - 0.13 12.8 0.2 11 6.6 0.0 2.7 1 1 1 2 2 2 0 FliG N-terminal domain EF-hand_7 PF13499.6 KXG49942.1 - 0.16 12.4 5.1 0.33 11.4 0.2 3.5 3 0 0 3 3 3 0 EF-hand domain pair Baculo_PEP_C PF04513.12 KXG49942.1 - 1.8 8.6 4.5 2.2 8.3 0.9 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.21 KXG49942.1 - 1.9 9.0 5.5 0.91 10.0 0.1 3.1 2 1 0 3 3 3 0 Spectrin repeat Aldo_ket_red PF00248.21 KXG49943.1 - 3.3e-42 144.7 0.0 7.8e-40 136.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Rit1_C PF17184.4 KXG49944.1 - 2.3e-74 250.3 0.0 8.7e-46 156.6 0.0 2.1 1 1 0 2 2 2 2 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KXG49944.1 - 5.9e-34 116.7 0.0 1.8e-33 115.1 0.0 1.8 2 0 0 2 2 2 1 Rit1 DUSP-like domain HAD_2 PF13419.6 KXG49945.1 - 9.7e-21 74.6 0.1 1.7e-20 73.8 0.0 1.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXG49945.1 - 4.7e-07 30.3 0.3 2.1e-06 28.2 0.3 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXG49945.1 - 1.3e-05 25.1 0.0 3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 KXG49945.1 - 0.0026 17.6 0.0 0.03 14.1 0.0 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KXG49945.1 - 0.0053 17.2 0.0 0.0071 16.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HD_3 PF13023.6 KXG49945.1 - 0.059 13.3 0.6 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 HD domain NUDIX PF00293.28 KXG49946.1 - 2.1e-18 66.6 0.0 3.3e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 KXG49947.1 - 2.3e-07 30.9 0.0 4.2e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain EST1_DNA_bind PF10373.9 KXG49948.1 - 4.7e-05 23.0 0.3 0.00049 19.7 0.3 2.2 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Glycos_transf_2 PF00535.26 KXG49949.1 - 1.4e-24 86.8 0.0 1e-22 80.7 0.0 2.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXG49949.1 - 1.3e-07 31.7 0.2 0.0039 17.1 0.1 2.8 2 1 1 3 3 3 2 Glycosyltransferase like family 2 Striatin PF08232.12 KXG49951.1 - 0.0094 16.6 0.3 0.0094 16.6 0.3 2.0 2 0 0 2 2 2 1 Striatin family DUF3482 PF11981.8 KXG49951.1 - 0.12 11.8 0.7 0.18 11.2 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Autophagy_N PF03986.13 KXG49953.1 - 3.1e-46 156.7 0.0 5.9e-46 155.8 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KXG49953.1 - 1.4e-15 56.5 0.5 2.4e-15 55.7 0.5 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KXG49953.1 - 2.3e-13 50.5 0.1 4.2e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain AAA_12 PF13087.6 KXG49954.1 - 4.5e-24 85.2 0.2 8.7e-24 84.2 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXG49954.1 - 3e-11 43.6 0.6 5.6e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain zf-CCCH_4 PF18044.1 KXG49954.1 - 1.3e-06 28.1 2.4 2.6e-06 27.1 2.4 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KXG49954.1 - 2e-06 27.6 1.4 2e-06 27.6 1.4 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2075 PF09848.9 KXG49954.1 - 3e-06 26.7 0.2 0.014 14.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) zf_CCCH_4 PF18345.1 KXG49954.1 - 3.2e-06 27.0 6.3 8e-06 25.7 6.3 1.7 1 0 0 1 1 1 1 Zinc finger domain AAA_19 PF13245.6 KXG49954.1 - 3.4e-05 24.2 0.1 0.00016 22.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Torus PF16131.5 KXG49954.1 - 0.00028 21.6 0.1 0.00067 20.3 0.1 1.6 1 0 0 1 1 1 1 Torus domain AAA_30 PF13604.6 KXG49954.1 - 0.011 15.5 0.0 0.033 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KXG49954.1 - 0.16 11.7 0.6 9.9 5.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase zf-CCCH_2 PF14608.6 KXG49954.1 - 0.44 11.1 2.0 1.6 9.3 2.0 2.1 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger SRP54_N PF02881.19 KXG49954.1 - 0.89 9.8 3.4 15 5.9 0.4 2.9 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain Cyclin_N PF00134.23 KXG49955.1 - 0.00053 19.7 0.0 0.008 15.9 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 KXG49955.1 - 0.00083 19.4 0.0 0.028 14.5 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Hairy_orange PF07527.13 KXG49955.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Hairy Orange LPD39 PF18858.1 KXG49956.1 - 0.038 14.1 8.6 0.027 14.6 5.0 2.4 2 1 0 2 2 2 0 Large polyvalent protein associated domain 39 Exonuc_VII_L PF02601.15 KXG49956.1 - 0.04 13.5 4.7 0.06 12.9 4.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GPO PF05929.11 KXG49956.1 - 0.25 10.9 5.5 0.37 10.4 5.5 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2570 PF10828.8 KXG49956.1 - 0.52 10.2 4.3 0.34 10.8 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) HAUS5 PF14817.6 KXG49956.1 - 0.73 8.5 9.3 1 8.1 9.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Nup88 PF10168.9 KXG49956.1 - 1.1 6.9 8.5 1.7 6.4 8.5 1.2 1 0 0 1 1 1 0 Nuclear pore component DUF4407 PF14362.6 KXG49956.1 - 2.2 7.5 7.2 3.2 7.0 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SecY PF00344.20 KXG49957.1 - 2.1e-72 244.0 7.9 2.6e-72 243.7 7.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KXG49957.1 - 7.4e-17 60.9 0.3 2e-16 59.5 0.3 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p MARVEL PF01284.23 KXG49957.1 - 0.64 10.0 0.0 0.64 10.0 0.0 3.1 2 1 0 2 2 2 0 Membrane-associating domain ArgJ PF01960.18 KXG49958.1 - 2.4e-151 503.7 1.1 2.8e-151 503.5 1.1 1.0 1 0 0 1 1 1 1 ArgJ family ORC2 PF04084.14 KXG49959.1 - 1.5e-119 398.8 0.0 1.8e-119 398.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 FUN14 PF04930.15 KXG49960.1 - 2.3e-10 40.7 0.3 4.8e-10 39.7 0.3 1.5 1 0 0 1 1 1 1 FUN14 family DUF543 PF04418.12 KXG49960.1 - 0.024 14.6 2.2 0.83 9.7 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) SOR_SNZ PF01680.17 KXG49961.1 - 4.1e-108 359.9 6.0 6.6e-108 359.2 6.0 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KXG49961.1 - 1.8e-08 34.0 8.0 2.3e-06 27.1 0.2 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG TetR_C_27 PF17935.1 KXG49961.1 - 0.0001 22.3 0.0 0.00051 20.1 0.0 2.0 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Dus PF01207.17 KXG49961.1 - 0.00048 19.3 0.5 0.18 10.9 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) IGPS PF00218.21 KXG49961.1 - 0.003 16.8 0.1 0.27 10.4 0.0 2.5 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 KXG49961.1 - 0.0045 16.5 0.7 0.15 11.5 0.1 3.1 2 2 1 3 3 3 1 Histidine biosynthesis protein NanE PF04131.14 KXG49961.1 - 0.021 14.0 1.4 0.21 10.8 0.0 2.5 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 KXG49961.1 - 0.04 13.3 0.3 0.04 13.3 0.3 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase PA PF02225.22 KXG49961.1 - 0.17 12.0 2.6 1.1 9.3 0.4 2.5 2 0 0 2 2 2 0 PA domain IBN_N PF03810.19 KXG49962.1 - 3.2e-06 26.9 1.2 9.3e-06 25.5 1.2 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Importin_rep_3 PF18806.1 KXG49962.1 - 0.0001 22.2 0.0 0.00059 19.8 0.0 2.4 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep PF18773.1 KXG49962.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Importin 13 repeat Phage_Coat_Gp8 PF05371.12 KXG49962.1 - 0.23 11.2 1.0 5.1 6.9 0.0 2.8 2 0 0 2 2 2 0 Phage major coat protein, Gp8 Creatinase_N_2 PF16189.5 KXG49963.1 - 3.4e-53 180.0 0.1 1.2e-51 175.0 0.0 3.1 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Sec8_exocyst PF04048.14 KXG49963.1 - 5.9e-44 149.4 1.2 1.6e-43 148.0 1.2 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Peptidase_M24 PF00557.24 KXG49963.1 - 8.6e-41 139.9 0.0 1.4e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KXG49963.1 - 6.1e-18 64.7 0.1 2e-17 63.0 0.1 2.0 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KXG49963.1 - 1.6e-17 64.4 0.0 1.4e-16 61.3 0.0 2.6 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Vps54_N PF10475.9 KXG49963.1 - 2.8e-09 36.7 0.2 1.6e-08 34.2 0.4 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KXG49963.1 - 0.0038 15.9 0.2 0.0071 15.0 0.2 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Dor1 PF04124.12 KXG49963.1 - 0.3 9.7 2.0 0.54 8.9 2.0 1.3 1 0 0 1 1 1 0 Dor1-like family DPBB_1 PF03330.18 KXG49964.1 - 4e-08 33.4 0.1 2.3e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 KXG49964.1 - 0.0022 18.0 1.1 0.0052 16.8 0.8 1.8 1 1 1 2 2 2 1 Pollen allergen BNR PF02012.20 KXG49964.1 - 4.5 7.7 5.8 0.44 10.7 0.7 2.2 2 0 0 2 2 2 0 BNR/Asp-box repeat GREB1 PF15782.5 KXG49964.1 - 7.8 3.5 6.6 9.8 3.1 6.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Inhibitor_I9 PF05922.16 KXG49965.1 - 5.5e-13 49.4 0.2 8e-13 48.9 0.2 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 DAHP_snth_FXD PF18152.1 KXG49965.1 - 0.072 12.9 0.1 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain HLH PF00010.26 KXG49966.1 - 6.2e-11 42.1 0.9 1.5e-10 40.9 0.9 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2400 PF09674.10 KXG49966.1 - 0.027 14.5 0.1 0.041 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) CN_hydrolase PF00795.22 KXG49967.1 - 9.8e-15 54.6 0.0 1.8e-14 53.7 0.0 1.5 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Pkinase PF00069.25 KXG49968.1 - 1.5e-12 47.5 0.0 4.2e-09 36.1 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG49968.1 - 2.7e-05 23.6 0.3 0.00035 20.0 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase SAC3_GANP PF03399.16 KXG49969.1 - 4.8e-102 341.3 6.6 6.7e-102 340.8 6.6 1.2 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KXG49969.1 - 5.7e-05 23.1 0.2 0.00018 21.5 0.1 1.9 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family DUF2841 PF11001.8 KXG49970.1 - 2.2e-45 153.7 0.0 7.5e-45 152.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) ABC_membrane PF00664.23 KXG49971.1 - 4.1e-80 269.4 29.7 1.5e-43 149.4 11.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXG49971.1 - 1.7e-51 174.3 0.0 7.8e-30 104.2 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXG49971.1 - 3.2e-09 36.6 4.5 0.0065 15.9 0.1 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KXG49971.1 - 2.7e-06 27.4 0.4 0.11 12.6 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXG49971.1 - 7.2e-05 22.7 0.5 0.019 14.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KXG49971.1 - 0.00016 22.1 0.3 0.46 10.8 0.3 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KXG49971.1 - 0.00089 18.9 0.7 1.9 8.3 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 KXG49971.1 - 0.0024 18.0 0.5 1.8 8.6 0.1 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain Dynamin_N PF00350.23 KXG49971.1 - 0.004 17.2 0.7 0.48 10.5 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 KXG49971.1 - 0.0059 17.1 0.1 0.82 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXG49971.1 - 0.006 16.4 0.1 1.9 8.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KXG49971.1 - 0.011 15.5 1.6 0.28 10.9 0.0 3.0 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 KXG49971.1 - 0.016 15.4 0.7 12 6.2 0.0 3.7 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KXG49971.1 - 0.02 15.2 1.6 4 7.7 0.0 3.4 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KXG49971.1 - 0.028 14.1 0.2 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 KXG49971.1 - 0.15 12.4 0.0 7.8 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 KXG49971.1 - 0.8 9.6 5.8 0.36 10.7 0.1 2.8 3 0 0 3 3 3 0 NACHT domain AIG1 PF04548.16 KXG49971.1 - 8.9 5.6 6.4 39 3.5 0.1 3.2 3 0 0 3 3 3 0 AIG1 family Ank_4 PF13637.6 KXG49972.1 - 7.6e-15 55.1 0.0 0.0051 17.4 0.0 6.2 6 1 0 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG49972.1 - 5e-13 48.0 3.2 0.0029 18.0 0.0 6.9 7 0 0 7 7 7 2 Ankyrin repeat Ank_2 PF12796.7 KXG49972.1 - 2.6e-10 40.7 0.0 0.037 14.6 0.0 4.0 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXG49972.1 - 4.3e-10 39.6 0.3 0.33 11.5 0.0 5.3 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KXG49972.1 - 1.3e-08 34.9 2.0 0.0037 17.6 0.0 5.6 4 2 2 6 6 6 3 Ankyrin repeats (many copies) bVLRF1 PF18826.1 KXG49974.1 - 5.4e-62 208.1 0.4 9.7e-62 207.3 0.4 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 KXG49974.1 - 0.00044 20.5 0.0 0.00095 19.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KXG49974.1 - 0.00062 20.1 0.6 0.0018 18.6 0.6 1.9 1 0 0 1 1 1 1 Ankyrin repeat EURL PF06937.11 KXG49974.1 - 0.051 13.0 1.2 0.098 12.1 0.2 1.9 2 0 0 2 2 2 0 EURL protein zf-C2H2_2 PF12756.7 KXG49974.1 - 0.15 12.4 0.1 0.3 11.4 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) U79_P34 PF03064.16 KXG49974.1 - 5.4 6.3 10.3 0.048 13.0 0.8 2.2 3 0 0 3 3 3 0 HSV U79 / HCMV P34 Myb_DNA-bind_6 PF13921.6 KXG49975.1 - 0.00037 20.7 0.1 0.00064 19.9 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXG49975.1 - 0.0005 20.2 1.2 0.00086 19.5 1.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 KXG49975.1 - 0.019 15.1 0.1 0.035 14.3 0.1 1.3 1 0 0 1 1 1 0 Rap1 Myb domain Adap_comp_sub PF00928.21 KXG49976.1 - 9.6e-84 280.9 0.0 1.2e-83 280.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXG49976.1 - 7.1e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KXG49976.1 - 0.0051 16.3 0.3 0.009 15.5 0.3 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain DUF4203 PF13886.6 KXG49977.1 - 7.2e-52 176.0 25.4 9.9e-52 175.5 25.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Erf4 PF10256.9 KXG49977.1 - 1.1e-38 131.9 0.0 2.2e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family SSB PF00436.25 KXG49978.1 - 4.1e-18 65.3 0.0 5e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.15 KXG49979.1 - 4.8e-93 311.5 19.9 6.1e-93 311.2 19.9 1.1 1 0 0 1 1 1 1 Pheromone A receptor PHO4 PF01384.20 KXG49979.1 - 0.023 13.7 0.0 0.052 12.6 0.0 1.4 1 1 0 1 1 1 0 Phosphate transporter family DUF3671 PF12420.8 KXG49979.1 - 0.045 13.8 0.8 0.045 13.8 0.8 2.5 3 0 0 3 3 3 0 Protein of unknown function Methyltransf_25 PF13649.6 KXG49980.1 - 4.6e-07 30.5 0.0 9.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG49980.1 - 6.8e-06 26.0 0.0 0.00027 20.7 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KXG49980.1 - 7.5e-06 25.8 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KXG49980.1 - 0.00021 21.1 0.0 0.00041 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG49980.1 - 0.00096 19.9 0.0 0.0042 17.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG49980.1 - 0.0014 19.2 0.0 0.0058 17.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG49980.1 - 0.0024 17.3 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KXG49980.1 - 0.0028 17.3 0.0 0.018 14.7 0.0 1.9 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 KXG49980.1 - 0.0093 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Fibrillarin PF01269.17 KXG49980.1 - 0.057 12.5 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin MTS PF05175.14 KXG49980.1 - 0.06 12.9 0.1 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_24 PF13578.6 KXG49980.1 - 0.063 14.3 0.0 0.14 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CorA PF01544.18 KXG49981.1 - 3.1e-16 59.6 3.6 3.1e-16 59.6 3.6 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DeoRC PF00455.22 KXG49981.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 DeoR C terminal sensor domain DUF2417 PF10329.9 KXG49981.1 - 0.021 14.2 0.9 0.04 13.3 0.9 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Lentiviral_Tat PF02998.14 KXG49981.1 - 0.061 13.4 0.1 0.21 11.7 0.1 2.0 1 0 0 1 1 1 0 Lentiviral Tat protein YgaB PF14182.6 KXG49981.1 - 0.25 11.8 2.9 0.81 10.1 0.5 2.8 2 1 1 3 3 3 0 YgaB-like protein But2 PF09792.9 KXG49982.1 - 4.3e-05 23.9 0.0 7.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain CW_binding_1 PF01473.20 KXG49984.1 - 1.6e-07 31.2 20.0 78 3.9 0.0 9.9 10 0 0 10 10 10 1 Putative cell wall binding repeat NAGLU PF05089.12 KXG49984.1 - 7.8 5.3 12.4 5.7 5.8 1.8 2.7 1 1 2 3 3 3 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain DUF3328 PF11807.8 KXG49985.1 - 3.1e-23 82.7 3.8 1.7e-22 80.3 3.8 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Tyrosinase PF00264.20 KXG49986.1 - 1.3e-39 136.8 7.3 2.1e-39 136.1 7.3 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase N2227 PF07942.12 KXG49987.1 - 4.7e-54 183.4 0.0 7.3e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 KXG49987.1 - 1.4e-08 35.3 0.3 1.2e-06 29.0 0.1 3.6 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG49987.1 - 1.4e-06 28.9 0.2 0.00024 21.7 0.0 3.6 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG49987.1 - 1.9e-05 25.3 0.2 0.00042 21.0 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG49987.1 - 0.0035 17.2 0.0 0.0082 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG49987.1 - 0.051 13.4 0.2 0.26 11.1 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain Exo_endo_phos PF03372.23 KXG49988.1 - 1.9e-08 34.1 0.0 3.7e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DCP1 PF06058.13 KXG49989.1 - 8.9e-29 99.8 0.0 1.5e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family LIDHydrolase PF10230.9 KXG49990.1 - 2.4e-68 230.6 0.0 8.6e-67 225.5 0.0 2.0 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KXG49990.1 - 9.9e-06 26.3 0.0 1.1e-05 26.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KXG49990.1 - 0.0011 18.9 0.0 0.03 14.2 0.0 2.4 3 0 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG49990.1 - 0.0013 18.1 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 KXG49990.1 - 0.0047 16.2 0.0 0.0082 15.3 0.0 1.3 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 KXG49990.1 - 0.08 13.0 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 KXG49990.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF1749 PF08538.10 KXG49990.1 - 0.14 11.2 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF900 PF05990.12 KXG49990.1 - 0.18 11.3 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) SMK-1 PF04802.15 KXG49991.1 - 9.6e-79 263.7 0.4 2e-78 262.6 0.4 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Pap_E4 PF02711.14 KXG49991.1 - 0.32 12.0 4.4 1.3 10.0 4.4 2.1 1 0 0 1 1 1 0 E4 protein SLC35F PF06027.12 KXG49992.1 - 4.4e-99 331.8 22.0 5.3e-99 331.5 22.0 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KXG49992.1 - 3.1e-09 36.2 3.7 5.5e-09 35.4 3.7 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KXG49992.1 - 3.3e-09 37.0 28.7 1.6e-05 25.1 8.7 2.4 2 1 0 2 2 2 2 EamA-like transporter family DUF5518 PF17647.1 KXG49992.1 - 0.018 15.2 2.1 0.018 15.2 2.1 3.5 3 1 0 3 3 3 0 Family of unknown function (DUF5518) DUF2516 PF10724.9 KXG49992.1 - 4.3 7.7 9.6 11 6.4 1.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) CALM_bind PF16025.5 KXG49993.1 - 0.11 13.0 6.0 0.22 12.0 6.0 1.5 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding PAP_assoc PF03828.19 KXG49994.1 - 5.3e-18 65.0 0.1 1.2e-17 63.9 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KXG49994.1 - 8.9e-05 22.7 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KXG49994.1 - 0.016 15.3 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase SE PF08491.10 KXG49995.1 - 1.8e-90 302.7 0.0 2.1e-88 295.9 0.0 2.1 1 1 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KXG49995.1 - 4.7e-12 45.8 0.0 3e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXG49995.1 - 4.5e-07 29.8 0.3 1.1e-05 25.3 0.4 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG49995.1 - 0.00036 20.7 0.6 0.00076 19.7 0.6 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXG49995.1 - 0.00053 19.2 0.0 0.029 13.4 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXG49995.1 - 0.00081 18.8 0.2 0.0012 18.3 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXG49995.1 - 0.00086 18.5 1.0 0.00086 18.5 1.0 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KXG49995.1 - 0.0011 18.2 0.2 0.0033 16.7 0.0 1.7 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.16 KXG49995.1 - 0.0063 16.2 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KXG49995.1 - 0.0078 15.5 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXG49995.1 - 0.008 15.3 0.4 0.014 14.4 0.4 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 KXG49995.1 - 0.014 15.9 0.2 0.078 13.5 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KXG49995.1 - 0.015 14.7 0.2 0.025 14.0 0.2 1.3 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.14 KXG49995.1 - 0.069 11.8 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KXG49995.1 - 0.079 11.8 0.1 0.63 8.8 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.20 KXG49995.1 - 0.17 11.9 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 KXG49995.1 - 0.2 11.6 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PPR PF01535.20 KXG49996.1 - 0.0095 16.1 0.5 7.7 7.0 0.0 4.3 5 0 0 5 5 5 1 PPR repeat PPR_long PF17177.4 KXG49996.1 - 0.013 14.9 0.0 0.042 13.2 0.0 1.8 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP Ku PF02735.16 KXG49997.1 - 8.5e-43 146.4 0.0 1.7e-42 145.4 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KXG49997.1 - 7.4e-34 117.4 0.0 1.1e-33 116.9 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KXG49997.1 - 4.2e-25 88.2 0.0 1.3e-24 86.7 0.0 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KXG49997.1 - 5.3e-11 42.0 0.0 1.1e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 KXG49997.1 - 0.053 13.3 0.5 0.34 10.7 0.5 2.3 1 1 0 1 1 1 0 HeH/LEM domain VWA_2 PF13519.6 KXG49997.1 - 0.097 13.3 0.0 0.9 10.2 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain VWA PF00092.28 KXG49997.1 - 0.12 12.6 0.0 0.67 10.2 0.0 2.2 1 1 0 1 1 1 0 von Willebrand factor type A domain FAD_binding_3 PF01494.19 KXG49998.1 - 5.9e-70 236.2 0.1 1.3e-68 231.8 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXG49998.1 - 4.6e-31 108.1 0.0 8e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KXG49998.1 - 0.014 14.7 0.0 0.074 12.3 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG49998.1 - 0.046 14.0 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 KXG49998.1 - 0.049 12.7 0.0 0.13 11.3 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.14 KXG49998.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 KXG49998.1 - 0.12 11.5 1.0 0.29 10.1 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein DUF3431 PF11913.8 KXG49999.1 - 1.1e-77 260.7 0.0 1.4e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) zf-CCCH PF00642.24 KXG50000.1 - 3e-09 36.6 1.5 5.7e-09 35.7 1.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KXG50000.1 - 3.1e-07 30.1 5.7 5.8e-07 29.3 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXG50000.1 - 5e-07 29.6 6.9 9.9e-07 28.7 6.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXG50000.1 - 1.1e-06 28.3 9.0 2e-06 27.5 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXG50000.1 - 3.3e-06 27.0 8.9 5.4e-06 26.3 8.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 KXG50000.1 - 3.7e-06 26.8 5.4 7e-06 25.9 5.4 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 KXG50000.1 - 5.3e-06 26.5 3.2 1e-05 25.5 3.2 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4 PF00097.25 KXG50000.1 - 9e-06 25.5 10.5 1.6e-05 24.7 10.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXG50000.1 - 6.2e-05 23.2 7.2 0.00013 22.2 7.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 KXG50000.1 - 0.00088 19.0 1.2 0.00088 19.0 1.2 1.7 2 0 0 2 2 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 KXG50000.1 - 0.0018 18.1 6.2 0.0035 17.2 6.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXG50000.1 - 0.017 15.2 8.6 0.033 14.4 8.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.6 KXG50000.1 - 0.1 13.1 1.6 0.23 12.0 1.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-Nse PF11789.8 KXG50000.1 - 0.34 10.8 3.0 0.65 9.9 3.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 KXG50000.1 - 0.46 10.8 4.5 1 9.7 4.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Mcp5_PH PF12814.7 KXG50001.1 - 7.5e-45 152.0 0.1 2e-44 150.6 0.1 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KXG50001.1 - 2.3e-07 31.3 0.0 6.3e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 PH domain Methyltransf_23 PF13489.6 KXG50002.1 - 7.9e-14 51.8 0.0 1.1e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG50002.1 - 4e-09 37.0 0.0 1e-08 35.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG50002.1 - 1.4e-05 25.7 0.0 4.8e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG50002.1 - 0.00039 20.2 0.0 0.0015 18.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG50002.1 - 0.00039 21.1 0.0 0.029 15.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KXG50002.1 - 0.07 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF2439 PF10382.9 KXG50003.1 - 1.4e-28 99.0 0.3 2.2e-28 98.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Peptidase_S9 PF00326.21 KXG50004.1 - 6.5e-42 143.4 0.1 1e-41 142.7 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KXG50004.1 - 7.5e-11 42.0 0.0 2.4e-10 40.3 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KXG50004.1 - 2.5e-07 30.8 0.1 0.00085 19.3 0.0 2.3 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 KXG50004.1 - 1.7e-06 27.5 0.2 0.0015 17.8 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 KXG50004.1 - 3.5e-06 26.8 0.0 7.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_4 PF08386.10 KXG50004.1 - 5.9e-06 26.3 0.0 1.7e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Peptidase_S15 PF02129.18 KXG50004.1 - 1e-05 25.3 1.3 0.08 12.5 2.1 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 KXG50004.1 - 0.00011 22.1 0.6 0.0014 18.5 0.6 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KXG50004.1 - 0.00018 21.3 1.4 0.4 10.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KXG50004.1 - 0.00038 19.5 0.5 0.0006 18.8 0.5 1.2 1 0 0 1 1 1 1 Carboxylesterase family PD40 PF07676.12 KXG50004.1 - 0.0046 16.9 1.3 2.8 8.0 0.1 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat FSH1 PF03959.13 KXG50004.1 - 0.0077 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) OLF PF02191.16 KXG50004.1 - 0.052 13.1 0.0 0.12 11.9 0.0 1.5 2 0 0 2 2 2 0 Olfactomedin-like domain Esterase_phd PF10503.9 KXG50004.1 - 0.074 12.5 0.4 1.3 8.4 0.4 2.3 1 1 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 KXG50004.1 - 0.095 12.5 0.0 0.61 9.8 0.0 2.1 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DUF5050 PF16472.5 KXG50004.1 - 0.098 11.9 0.0 11 5.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5050) DUF5074 PF16819.5 KXG50004.1 - 0.11 12.6 0.1 22 5.1 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5074) SH3_9 PF14604.6 KXG50005.1 - 4.2e-16 58.5 0.1 8.2e-16 57.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXG50005.1 - 3e-14 52.4 0.1 5.2e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXG50005.1 - 4e-09 36.0 0.0 6.9e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 KXG50005.1 - 1.6e-08 34.5 2.0 2.6e-08 33.8 2.0 1.3 1 0 0 1 1 1 1 BAR domain p450 PF00067.22 KXG50007.1 - 4.2e-45 154.3 0.0 6.1e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KXG50008.1 - 0.0043 16.9 0.0 0.0092 15.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KXG50008.1 - 0.11 12.4 1.5 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 F-box Alpha-amylase PF00128.24 KXG50009.1 - 4.4e-16 59.4 1.8 2.6e-15 56.9 1.2 2.5 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KXG50009.1 - 1.2e-14 54.6 0.1 2.1e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KXG50009.1 - 3.4e-05 23.5 0.0 7.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXG50009.1 - 0.075 13.0 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Abhydrolase_1 PF00561.20 KXG50010.1 - 3e-11 43.5 0.0 5.2e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG50010.1 - 1.5e-10 42.1 0.0 1.9e-10 41.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG50010.1 - 7e-10 38.6 0.0 8.6e-09 35.0 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 KXG50010.1 - 1.5e-06 28.2 0.0 0.00032 20.7 0.0 2.1 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 KXG50010.1 - 7.3e-05 22.7 0.0 0.0004 20.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 KXG50010.1 - 0.00054 19.7 0.0 0.0026 17.5 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KXG50010.1 - 0.003 17.1 0.0 1 8.8 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Palm_thioest PF02089.15 KXG50010.1 - 0.023 14.6 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Thioesterase PF00975.20 KXG50010.1 - 0.039 14.1 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_4 PF08386.10 KXG50010.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein LIDHydrolase PF10230.9 KXG50010.1 - 0.22 11.1 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Glyco_hydro_16 PF00722.21 KXG50011.1 - 3.8e-10 39.5 0.0 2e-09 37.2 0.0 1.9 1 1 0 2 2 2 1 Glycosyl hydrolases family 16 Bin3 PF06859.12 KXG50012.1 - 1.8e-32 112.2 0.0 2.5e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 KXG50012.1 - 2.3e-12 47.1 0.0 3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG50012.1 - 4.2e-12 46.1 0.0 4.8e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG50012.1 - 2.4e-09 37.8 0.0 4.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG50012.1 - 1.9e-08 34.9 0.0 3.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG50012.1 - 1.6e-07 31.9 0.0 2.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXG50012.1 - 0.00015 21.4 0.0 0.00047 19.7 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KXG50012.1 - 0.00067 19.1 0.0 0.0014 18.1 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KXG50012.1 - 0.0064 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KXG50012.1 - 0.022 13.7 0.0 0.031 13.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 KXG50012.1 - 0.12 12.0 0.0 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Jacalin PF01419.17 KXG50013.1 - 0.017 15.1 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 Jacalin-like lectin domain GST_N_2 PF13409.6 KXG50014.1 - 3e-06 27.4 0.0 6.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXG50014.1 - 1.3e-05 25.6 0.0 3.1e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXG50014.1 - 0.0067 16.4 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXG50014.1 - 0.041 14.1 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXG50014.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Prenyltrans PF00432.21 KXG50015.1 - 4.7e-07 29.4 0.2 0.44 10.3 0.0 3.8 3 0 0 3 3 3 3 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KXG50015.1 - 0.0014 17.7 0.2 2.2 7.3 0.0 3.2 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain Terpene_synth PF01397.21 KXG50015.1 - 0.043 13.5 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain SQHop_cyclase_N PF13249.6 KXG50015.1 - 0.11 11.6 0.1 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain MFS_1 PF07690.16 KXG50017.1 - 8.1e-41 140.1 48.9 8.1e-41 140.1 48.9 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG50017.1 - 1.8e-13 49.8 23.9 3e-13 49.1 23.5 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Trp_halogenase PF04820.14 KXG50018.1 - 6e-28 97.9 0.0 2.8e-14 52.9 0.0 2.3 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KXG50018.1 - 1e-10 41.4 0.0 2.1e-10 40.4 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXG50018.1 - 3.9e-06 27.0 0.1 8.4e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXG50018.1 - 0.00095 18.6 0.5 0.0016 17.9 0.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG50018.1 - 0.001 18.4 0.0 0.0023 17.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG50018.1 - 0.0088 15.7 0.2 0.066 12.8 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KXG50018.1 - 0.011 14.9 0.1 0.017 14.3 0.1 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KXG50018.1 - 0.013 14.2 0.3 0.047 12.4 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KXG50018.1 - 0.048 12.8 0.1 0.07 12.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain ketoacyl-synt PF00109.26 KXG50019.1 - 4.2e-79 265.7 0.1 8.9e-79 264.6 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXG50019.1 - 2.4e-36 125.8 0.0 5.4e-36 124.7 0.0 1.5 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXG50019.1 - 2.1e-35 121.3 0.1 5.5e-35 119.9 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SAT PF16073.5 KXG50019.1 - 4.6e-17 62.5 0.3 3.6e-15 56.3 0.0 3.0 2 1 1 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 KXG50019.1 - 3.8e-07 30.4 0.9 1.2e-06 28.8 0.9 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KXG50019.1 - 1.2e-06 28.9 0.0 3.7e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KXG50019.1 - 2.6e-05 23.7 0.2 5.8e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_2 PF00891.18 KXG50020.1 - 1.6e-24 86.4 0.0 2.2e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KXG50020.1 - 0.00011 22.8 0.0 0.00022 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG50020.1 - 0.0023 18.6 0.0 0.0045 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG50020.1 - 0.0044 16.8 0.0 0.007 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXG50020.1 - 0.019 14.5 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain YtkA PF13115.6 KXG50020.1 - 0.07 13.7 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 YtkA-like Methyltransf_16 PF10294.9 KXG50020.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 KXG50021.1 - 8.2e-21 74.3 0.0 6.4e-20 71.4 0.0 2.0 2 0 0 2 2 2 1 O-methyltransferase domain FeoC PF09012.10 KXG50021.1 - 0.006 16.6 0.0 0.05 13.7 0.0 2.2 2 0 0 2 2 2 1 FeoC like transcriptional regulator Dimerisation PF08100.11 KXG50021.1 - 0.059 13.4 1.5 0.19 11.8 1.5 2.0 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_PK PF05891.12 KXG50021.1 - 0.068 12.7 0.0 0.33 10.5 0.0 2.0 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Rrf2 PF02082.20 KXG50021.1 - 0.077 13.3 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 Transcriptional regulator Methyltransf_2 PF00891.18 KXG50022.1 - 9.4e-19 67.5 0.0 1.3e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KXG50022.1 - 2.9e-06 27.2 0.1 8.5e-06 25.7 0.1 1.8 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 KXG50022.1 - 4e-05 23.5 0.0 9.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain G6PD_C PF02781.16 KXG50022.1 - 0.021 14.0 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, C-terminal domain Epimerase PF01370.21 KXG50023.1 - 0.00011 21.7 0.0 0.00039 20.0 0.0 1.8 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXG50023.1 - 0.0093 15.2 0.0 1.5 7.9 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein p450 PF00067.22 KXG50024.1 - 6.9e-62 209.7 0.0 8.1e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.7 KXG50025.1 - 8.5e-26 90.4 2.6 9.3e-18 64.6 0.6 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG50025.1 - 7.5e-22 77.4 5.6 4.9e-11 42.9 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG50025.1 - 6.3e-21 72.2 0.6 0.0014 18.9 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KXG50025.1 - 1.8e-18 66.4 9.5 3.3e-09 36.8 0.1 4.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KXG50025.1 - 1.9e-18 66.0 4.2 0.00027 21.3 0.1 4.4 4 0 0 4 4 4 4 Ankyrin repeat bZIP_1 PF00170.21 KXG50025.1 - 0.9 9.7 9.3 1.5 9.0 9.3 1.3 1 0 0 1 1 1 0 bZIP transcription factor ADH_zinc_N PF00107.26 KXG50026.1 - 2.3e-22 79.3 0.0 3.1e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG50026.1 - 0.057 14.5 0.0 0.091 13.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Aldedh PF00171.22 KXG50027.1 - 1.5e-131 439.1 0.0 1.8e-131 438.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXG50027.1 - 0.077 12.0 0.1 0.16 11.0 0.1 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) zf-Dof PF02701.15 KXG50028.1 - 0.059 13.5 2.0 11 6.3 0.0 4.0 4 1 0 4 4 4 0 Dof domain, zinc finger Glyco_hydro_61 PF03443.14 KXG50029.1 - 1.8e-46 158.7 0.1 2.2e-46 158.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Abhydrolase_2 PF02230.16 KXG50030.1 - 0.009 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 KXG50030.1 - 0.035 13.6 0.2 0.035 13.6 0.2 1.5 2 0 0 2 2 2 0 Esterase PHB depolymerase Esterase PF00756.20 KXG50030.1 - 0.054 13.1 0.3 0.086 12.5 0.3 1.4 1 1 0 1 1 1 0 Putative esterase SnoaL_2 PF12680.7 KXG50032.1 - 0.00011 22.7 0.2 0.00017 22.2 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain FA_hydroxylase PF04116.13 KXG50033.1 - 2.3e-25 89.5 13.6 2.3e-25 89.5 13.6 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily RTC PF01137.21 KXG50035.1 - 1.1e-50 172.0 0.0 1.3e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase CBFD_NFYB_HMF PF00808.23 KXG50035.1 - 0.004 17.4 0.0 0.86 9.9 0.0 2.4 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF588 PF04535.12 KXG50035.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF588) DUF4629 PF15442.6 KXG50035.1 - 0.11 12.8 0.0 4.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) CPSase_L_D2 PF02786.17 KXG50037.1 - 1.6e-57 194.5 0.0 2.3e-57 193.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KXG50037.1 - 4.4e-32 110.4 0.0 9.3e-32 109.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KXG50037.1 - 8.9e-28 97.0 0.0 1.5e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KXG50037.1 - 1.2e-10 41.0 0.4 5.1e-10 39.0 0.3 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KXG50037.1 - 2.6e-08 33.7 0.0 5.8e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXG50037.1 - 2.2e-05 24.1 0.1 3.9e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KXG50037.1 - 7e-05 22.9 0.0 0.00017 21.7 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 KXG50037.1 - 9.7e-05 21.7 0.0 0.00027 20.3 0.0 1.7 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp RnfC_N PF13375.6 KXG50037.1 - 0.00043 20.2 0.0 0.0019 18.1 0.0 2.1 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain RimK PF08443.11 KXG50037.1 - 0.0026 17.4 0.2 0.22 11.1 0.0 2.9 3 0 0 3 3 3 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 KXG50037.1 - 0.0098 15.4 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KXG50037.1 - 0.072 12.9 0.1 0.21 11.4 0.1 1.8 1 1 0 1 1 1 0 Biotin-lipoyl like ATPgrasp_Ter PF15632.6 KXG50037.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Carboxyl_trans PF01039.22 KXG50038.1 - 1.1e-75 255.2 0.0 1.5e-75 254.8 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ArAE_2_N PF10337.9 KXG50041.1 - 2.3e-122 409.4 0.2 4.9e-121 405.0 0.1 2.2 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KXG50041.1 - 3e-61 207.2 0.1 1e-60 205.4 0.0 2.0 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 HPP PF04982.13 KXG50041.1 - 1.6e-42 144.5 7.6 1.6e-42 144.5 7.6 3.9 3 1 0 3 3 3 2 HPP family FUSC_2 PF13515.6 KXG50041.1 - 1.2e-08 35.2 15.0 1.2e-08 35.2 15.0 5.2 5 1 0 5 5 5 2 Fusaric acid resistance protein-like ALMT PF11744.8 KXG50041.1 - 1.7 7.4 6.3 0.2 10.4 1.2 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF3592 PF12158.8 KXG50041.1 - 7.2 6.6 10.1 0.073 13.1 0.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3592) AA_permease PF00324.21 KXG50042.1 - 6.6e-114 381.1 41.2 7.6e-114 380.9 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG50042.1 - 2e-39 135.7 47.6 2.7e-39 135.2 47.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4231 PF14015.6 KXG50042.1 - 0.12 12.9 0.3 0.12 12.9 0.3 4.0 3 2 0 4 4 4 0 Protein of unknown function (DUF4231) S-methyl_trans PF02574.16 KXG50043.1 - 5.5e-56 190.3 0.0 6.5e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase DUF1772 PF08592.11 KXG50044.1 - 7.2e-05 23.1 0.1 0.0001 22.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) adh_short_C2 PF13561.6 KXG50045.1 - 5.7e-40 137.3 0.1 1.7e-25 89.9 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG50045.1 - 5.1e-29 101.1 0.7 2.9e-28 98.7 0.7 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG50045.1 - 9.1e-08 32.2 0.5 2.3e-07 30.9 0.2 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXG50045.1 - 0.023 14.1 0.1 2.2 7.7 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXG50045.1 - 0.073 12.2 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4056 PF13265.6 KXG50045.1 - 0.21 10.9 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) GAS PF13851.6 KXG50046.1 - 0.054 12.8 8.3 0.019 14.3 1.6 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Uso1_p115_C PF04871.13 KXG50046.1 - 0.96 9.8 6.7 2.3 8.6 6.7 1.7 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region RNAse_A_bac PF18431.1 KXG50046.1 - 2 9.4 5.4 2 9.4 2.6 2.2 1 1 1 2 2 2 0 Bacterial CdiA-CT RNAse A domain DUF16 PF01519.16 KXG50046.1 - 2.7 8.5 5.8 11 6.6 2.8 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 APG6_N PF17675.1 KXG50046.1 - 4.1 7.9 9.4 3.9 8.0 7.6 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region Med9 PF07544.13 KXG50046.1 - 4.9 7.3 5.8 31 4.8 0.9 2.6 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 RabGAP-TBC PF00566.18 KXG50049.1 - 9e-48 162.8 0.0 1.4e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 KXG50049.1 - 7.9e-05 22.5 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 KXG50049.1 - 0.0066 16.3 0.1 0.029 14.3 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain CNH PF00780.22 KXG50050.1 - 1e-65 222.1 0.0 1.7e-65 221.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KXG50050.1 - 7.6e-35 120.8 0.5 1.5e-34 119.9 0.5 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KXG50050.1 - 7e-13 48.9 0.0 2.8e-12 46.9 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KXG50050.1 - 0.1 13.1 0.0 0.33 11.5 0.0 1.9 2 0 0 2 2 2 0 PH domain 2OG-FeII_Oxy_2 PF13532.6 KXG50051.1 - 3.9e-31 108.8 0.0 9.7e-31 107.5 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SHOCT PF09851.9 KXG50051.1 - 0.00057 19.5 1.4 0.0011 18.6 1.4 1.5 1 0 0 1 1 1 1 Short C-terminal domain AMP-binding PF00501.28 KXG50052.1 - 1.4e-75 254.5 0.0 1.9e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG50052.1 - 6.9e-15 55.8 0.2 1.5e-14 54.7 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 KXG50053.1 - 0.0018 17.4 1.5 0.0033 16.5 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF805 PF05656.14 KXG50053.1 - 0.024 15.1 0.1 0.072 13.5 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF805) WD40 PF00400.32 KXG50054.1 - 3.6e-15 56.1 4.7 0.16 12.9 0.5 8.0 8 1 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG50054.1 - 9.4e-06 25.8 0.0 0.0063 16.8 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain NDUF_B12 PF08122.12 KXG50055.1 - 1.3e-27 95.6 1.1 1.9e-27 95.0 1.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family CAF1 PF04857.20 KXG50056.1 - 2.5e-22 79.5 0.0 4.4e-11 42.5 0.0 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease Pkinase PF00069.25 KXG50057.1 - 2.7e-22 79.4 0.0 5.3e-22 78.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG50057.1 - 9.5e-06 25.1 0.0 3e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXG50057.1 - 0.066 12.0 0.0 0.093 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXG50057.1 - 0.082 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXG50057.1 - 0.083 12.8 0.0 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Cu_amine_oxid PF01179.20 KXG50058.1 - 1.5e-158 528.1 0.0 1.8e-158 527.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KXG50058.1 - 2.5e-24 85.6 1.7 1.2e-22 80.2 0.1 2.5 1 1 1 2 2 2 2 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KXG50058.1 - 6.5e-14 51.9 0.0 1.1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain TPR_2 PF07719.17 KXG50059.1 - 2.8e-09 36.4 4.3 0.00038 20.4 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXG50059.1 - 4.6e-07 29.4 3.7 0.033 14.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat MARVEL PF01284.23 KXG50059.1 - 7.6e-07 29.2 4.3 1.3e-06 28.5 4.3 1.3 1 0 0 1 1 1 1 Membrane-associating domain TPR_12 PF13424.6 KXG50059.1 - 8.8e-06 25.9 2.8 0.0069 16.7 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXG50059.1 - 0.00036 20.3 1.8 0.29 11.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXG50059.1 - 0.0011 19.0 5.3 0.0092 16.1 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXG50059.1 - 0.0035 17.9 2.1 2.8 8.7 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat Cas9_a PF18470.1 KXG50059.1 - 0.0044 16.6 0.1 0.0075 15.8 0.1 1.2 1 0 0 1 1 1 1 Cas9 alpha-helical lobe domain TPR_19 PF14559.6 KXG50059.1 - 0.0099 16.4 0.7 0.51 10.9 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXG50059.1 - 0.05 14.5 4.1 0.13 13.2 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KXG50059.1 - 0.067 13.3 0.8 0.99 9.5 0.3 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 KXG50059.1 - 0.13 12.9 0.8 1.5 9.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat GFO_IDH_MocA PF01408.22 KXG50061.1 - 5e-25 88.7 0.1 8.6e-25 87.9 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXG50061.1 - 1.4e-10 41.2 0.0 2.6e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Methyltransf_24 PF13578.6 KXG50061.1 - 0.0027 18.7 0.0 0.0088 17.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain DapB_N PF01113.20 KXG50061.1 - 0.0031 17.6 0.1 0.0058 16.8 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.16 KXG50061.1 - 0.0031 18.1 0.1 0.024 15.3 0.0 2.1 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 KXG50061.1 - 0.09 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Shisa PF13908.6 KXG50062.1 - 0.0023 18.2 0.2 0.0036 17.6 0.2 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4448 PF14610.6 KXG50062.1 - 0.058 13.2 0.1 0.098 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Chitin_bind_1 PF00187.19 KXG50063.1 - 3e-07 30.8 4.4 3e-07 30.8 4.4 2.4 2 1 0 2 2 2 1 Chitin recognition protein LysM PF01476.20 KXG50063.1 - 4.3e-05 23.5 0.2 8.4e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 LysM domain Glyco_hydro_18 PF00704.28 KXG50063.1 - 0.088 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 HPP PF04982.13 KXG50066.1 - 6.9e-37 126.3 8.8 6.9e-37 126.3 8.8 1.8 2 0 0 2 2 2 1 HPP family ABC_tran PF00005.27 KXG50067.1 - 2.9e-45 154.2 0.0 1.1e-21 77.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KXG50067.1 - 7.4e-21 74.0 2.5 7.4e-21 74.0 2.5 2.8 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 KXG50067.1 - 4.1e-18 66.2 0.1 0.00026 20.9 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXG50067.1 - 1.4e-10 41.0 0.2 0.12 11.8 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXG50067.1 - 5.3e-08 33.6 0.8 0.06 13.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KXG50067.1 - 6.8e-08 32.1 0.5 0.0022 17.7 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KXG50067.1 - 1.7e-06 28.0 0.0 0.042 13.5 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 KXG50067.1 - 1.2e-05 25.6 0.0 0.0056 16.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXG50067.1 - 3.4e-05 24.3 0.0 0.52 10.7 0.0 3.5 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXG50067.1 - 3.4e-05 24.4 0.1 0.11 13.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KXG50067.1 - 3.6e-05 24.2 0.1 0.099 13.0 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KXG50067.1 - 4e-05 23.7 0.1 0.024 14.7 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXG50067.1 - 5.2e-05 23.2 3.6 0.0053 16.7 0.1 2.9 4 0 0 4 4 2 1 RsgA GTPase AAA_22 PF13401.6 KXG50067.1 - 5.5e-05 23.5 0.0 0.19 12.0 0.2 2.8 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KXG50067.1 - 0.0001 22.6 0.1 2.1 8.8 0.0 3.6 4 0 0 4 4 3 2 RNA helicase NB-ARC PF00931.22 KXG50067.1 - 0.00031 20.0 0.0 0.93 8.6 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain AAA_5 PF07728.14 KXG50067.1 - 0.00034 20.6 0.1 1.3 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KXG50067.1 - 0.00053 19.8 0.3 1.8 8.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KXG50067.1 - 0.00053 19.9 0.3 0.8 9.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 KXG50067.1 - 0.00082 19.6 1.4 0.1 12.7 0.0 3.3 4 0 0 4 4 3 1 AAA domain Roc PF08477.13 KXG50067.1 - 0.0045 17.2 0.0 5.4 7.2 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 KXG50067.1 - 0.0061 16.6 0.0 6.1 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KXG50067.1 - 0.009 15.6 0.4 5.8 6.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KXG50067.1 - 0.0094 15.5 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 KXG50067.1 - 0.01 15.4 0.0 1.2 8.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 KXG50067.1 - 0.036 13.7 0.0 0.31 10.7 0.0 2.5 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 KXG50067.1 - 0.044 13.7 0.2 3.5 7.5 0.1 2.7 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 KXG50067.1 - 0.11 12.5 0.0 15 5.5 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain Ras PF00071.22 KXG50067.1 - 0.12 12.0 0.2 15 5.1 0.0 2.9 3 0 0 3 3 3 0 Ras family ATPase_2 PF01637.18 KXG50067.1 - 0.13 12.2 0.2 27 4.6 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea FeoB_N PF02421.18 KXG50067.1 - 0.14 11.7 0.0 4.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF2813 PF11398.8 KXG50067.1 - 0.17 11.1 1.2 17 4.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) DUF87 PF01935.17 KXG50067.1 - 0.28 11.3 2.9 21 5.1 0.0 3.1 3 1 0 3 3 3 0 Helicase HerA, central domain AAA_30 PF13604.6 KXG50067.1 - 0.32 10.7 3.8 3.9 7.1 0.0 3.4 5 0 0 5 5 4 0 AAA domain Dynamin_N PF00350.23 KXG50067.1 - 0.37 10.8 3.0 33 4.5 0.0 3.6 3 1 0 4 4 3 0 Dynamin family DUF3584 PF12128.8 KXG50067.1 - 3.3 5.1 7.8 0.23 8.9 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) UQ_con PF00179.26 KXG50069.1 - 7.5e-43 145.5 0.0 3.5e-42 143.4 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Cyclin_C_2 PF16899.5 KXG50069.1 - 1.9e-34 118.2 0.1 8.9e-31 106.4 0.0 3.0 3 0 0 3 3 3 2 Cyclin C-terminal domain Cyclin_N PF00134.23 KXG50069.1 - 2.6e-05 24.0 0.0 4.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain UBA_3 PF09288.10 KXG50069.1 - 0.00022 20.9 0.0 0.0005 19.8 0.0 1.6 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 KXG50069.1 - 0.0013 18.5 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic E2 family B AAA PF00004.29 KXG50070.1 - 1.2e-40 139.0 0.0 2.2e-40 138.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXG50070.1 - 2.6e-10 39.9 0.5 4.8e-10 39.1 0.5 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KXG50070.1 - 1.3e-09 37.8 0.1 2.4e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KXG50070.1 - 6.2e-06 26.4 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXG50070.1 - 1e-05 25.9 0.2 0.02 15.1 0.1 2.5 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 KXG50070.1 - 1.4e-05 24.4 0.0 2.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KXG50070.1 - 4.1e-05 23.6 0.0 0.00012 22.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXG50070.1 - 0.00034 21.0 0.3 0.0075 16.7 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXG50070.1 - 0.00056 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KXG50070.1 - 0.0063 17.0 0.1 0.018 15.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 KXG50070.1 - 0.0074 16.5 0.0 0.0074 16.5 0.0 1.9 3 0 0 3 3 1 1 AAA domain PhoH PF02562.16 KXG50070.1 - 0.015 14.7 0.6 0.51 9.7 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 KXG50070.1 - 0.016 15.4 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXG50070.1 - 0.018 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 KXG50070.1 - 0.02 14.7 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KXG50070.1 - 0.026 13.8 0.2 0.51 9.6 0.1 2.2 1 1 0 2 2 2 0 KaiC AAA_14 PF13173.6 KXG50070.1 - 0.028 14.5 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXG50070.1 - 0.03 14.2 0.1 0.54 10.2 0.1 2.3 1 1 0 1 1 1 0 NACHT domain TIP49 PF06068.13 KXG50070.1 - 0.031 13.5 0.6 0.056 12.6 0.0 1.7 3 0 0 3 3 3 0 TIP49 P-loop domain RNA_helicase PF00910.22 KXG50070.1 - 0.048 14.0 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KXG50070.1 - 0.06 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KXG50070.1 - 0.079 12.5 0.1 0.35 10.3 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KXG50070.1 - 0.088 12.1 0.1 0.2 10.9 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KXG50070.1 - 0.13 11.9 1.1 0.59 9.7 0.4 2.3 1 1 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 KXG50070.1 - 0.15 11.7 0.5 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain DUF2075 PF09848.9 KXG50070.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KXG50070.1 - 0.28 10.9 2.1 0.33 10.7 0.3 2.1 2 1 0 2 2 2 0 AAA domain WD40 PF00400.32 KXG50071.1 - 1.4e-17 63.7 11.8 1.8e-05 25.4 0.5 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG50071.1 - 0.0008 19.7 0.0 0.33 11.3 0.0 3.3 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cwf_Cwc_15 PF04889.12 KXG50071.1 - 0.06 13.1 5.6 0.12 12.1 5.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein VID27_N PF17748.1 KXG50071.1 - 0.071 13.0 0.7 0.2 11.5 0.7 1.7 1 0 0 1 1 1 0 VID27 N-terminal region PBP1_TM PF14812.6 KXG50071.1 - 0.072 13.5 3.6 0.2 12.1 3.6 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 KXG50071.1 - 0.22 11.9 7.6 0.43 11.0 7.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCIP PF13324.6 KXG50071.1 - 0.26 10.8 1.4 0.39 10.3 1.4 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 KXG50071.1 - 1.2 8.4 5.7 1.8 7.8 5.7 1.2 1 0 0 1 1 1 0 NOA36 protein Mg_trans_NIPA PF05653.14 KXG50072.1 - 1.3e-59 201.7 9.0 2.5e-56 191.0 6.2 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KXG50072.1 - 5.4e-05 23.4 0.5 5.4e-05 23.4 0.5 3.4 3 1 0 3 3 3 1 EamA-like transporter family DUF1461 PF07314.11 KXG50072.1 - 0.49 10.3 1.9 1.2 9.0 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) DUF2569 PF10754.9 KXG50072.1 - 2.2 8.7 7.2 1.1 9.7 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Glyco_hydro_3 PF00933.21 KXG50073.1 - 1.8e-63 214.9 0.0 2.3e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KXG50073.1 - 2.7e-53 181.0 0.0 4.7e-53 180.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KXG50073.1 - 3.1e-21 75.3 1.8 3.4e-21 75.1 0.2 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain fn3_5 PF06280.12 KXG50073.1 - 0.2 12.4 1.7 0.43 11.3 1.7 1.5 1 0 0 1 1 1 0 Fn3-like domain KLRAQ PF10205.9 KXG50074.1 - 0.015 15.5 0.4 0.057 13.7 0.4 2.0 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Med21 PF11221.8 KXG50074.1 - 0.085 13.1 0.5 0.085 13.1 0.5 3.4 3 1 0 3 3 2 0 Subunit 21 of Mediator complex FlaC_arch PF05377.11 KXG50074.1 - 0.1 13.0 0.5 0.1 13.0 0.5 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 KXG50074.1 - 0.37 11.1 8.0 0.14 12.4 3.5 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain GAS PF13851.6 KXG50074.1 - 0.37 10.1 6.0 0.2 11.0 2.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding MAD PF05557.13 KXG50074.1 - 0.41 9.0 11.1 1.1 7.5 3.7 2.9 2 1 1 3 3 3 0 Mitotic checkpoint protein YabA PF06156.13 KXG50074.1 - 1.6 9.4 3.3 7.3 7.3 0.3 2.5 2 0 0 2 2 2 0 Initiation control protein YabA TolA_bind_tri PF16331.5 KXG50074.1 - 2.1 8.5 8.3 6 7.0 0.9 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF4140 PF13600.6 KXG50074.1 - 2.6 8.6 6.6 0.28 11.6 0.4 2.6 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 KXG50074.1 - 3.8 7.3 9.1 0.68 9.7 4.5 2.0 2 0 0 2 2 2 0 Septum formation initiator DivIVA PF05103.13 KXG50074.1 - 5.1 7.2 6.7 0.92 9.6 1.2 2.3 2 0 0 2 2 2 0 DivIVA protein VASt PF16016.5 KXG50075.1 - 1.3e-35 123.1 0.0 2.2e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KXG50075.1 - 2.2e-22 79.1 0.0 3.6e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Trypan_PARP PF05887.11 KXG50076.1 - 2.4 8.1 26.5 5.2e+03 -2.7 26.5 2.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Amelin PF05111.12 KXG50076.1 - 4.1 6.4 12.8 5.9 5.9 12.5 1.5 1 1 0 1 1 1 0 Ameloblastin precursor (Amelin) Amidase PF01425.21 KXG50077.1 - 5.3e-06 25.7 0.7 0.00017 20.7 0.5 2.1 2 0 0 2 2 2 2 Amidase His_biosynth PF00977.21 KXG50077.1 - 0.19 11.1 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein Sugar_tr PF00083.24 KXG50079.1 - 8.3e-66 222.7 22.6 9.5e-66 222.5 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG50079.1 - 6e-13 48.4 33.9 3.6e-12 45.9 29.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Thioredoxin PF00085.20 KXG50080.1 - 5.5e-27 93.8 0.1 7.3e-27 93.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXG50080.1 - 7.5e-08 32.6 0.1 2.6e-06 27.6 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KXG50080.1 - 3.7e-07 30.6 0.1 3.8e-06 27.3 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 KXG50080.1 - 2.6e-05 24.0 0.6 0.0012 18.6 0.2 2.3 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 KXG50080.1 - 3.2e-05 23.8 0.0 5.1e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 KXG50080.1 - 7.7e-05 22.2 0.1 0.0003 20.3 0.0 1.8 1 1 1 2 2 2 1 OST3 / OST6 family, transporter family TraF PF13728.6 KXG50080.1 - 0.00019 21.3 0.1 0.00027 20.9 0.1 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 KXG50080.1 - 0.0027 17.5 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KXG50080.1 - 0.0028 17.8 0.1 0.0066 16.6 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.6 KXG50080.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_5 PF13743.6 KXG50080.1 - 0.015 14.9 0.1 0.1 12.3 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 KXG50080.1 - 0.02 15.1 0.1 0.044 14.0 0.1 1.6 1 0 0 1 1 1 0 Glutaredoxin DSBA PF01323.20 KXG50080.1 - 0.023 14.5 1.4 2.4 7.9 0.1 2.2 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KXG50080.1 - 0.033 14.3 0.1 5 7.3 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin Phosducin PF02114.16 KXG50080.1 - 0.09 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosducin HyaE PF07449.11 KXG50080.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.4 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE SIMPL PF04402.14 KXG50081.1 - 2.7e-11 44.3 0.0 3.1e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DNAP_B_exo_N PF08452.10 KXG50081.1 - 0.2 11.1 1.3 0.37 10.2 1.3 1.4 1 0 0 1 1 1 0 DNA polymerase family B exonuclease domain, N-terminal DUF5362 PF17319.2 KXG50081.1 - 0.23 11.3 0.0 0.37 10.7 0.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5362) HMA PF00403.26 KXG50082.1 - 5.6e-11 42.7 0.4 7.1e-11 42.4 0.4 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain ABC2_membrane PF01061.24 KXG50083.1 - 2.6e-79 265.5 58.9 5.6e-42 143.6 16.3 2.5 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 KXG50083.1 - 1.2e-35 123.0 0.0 6.8e-17 62.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXG50083.1 - 2.2e-26 91.5 0.6 1.4e-20 73.0 0.0 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KXG50083.1 - 6.1e-14 52.4 0.1 1.5e-13 51.1 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KXG50083.1 - 6.6e-07 28.8 36.9 0.00064 18.9 15.4 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KXG50083.1 - 6e-06 26.7 0.1 0.0046 17.4 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KXG50083.1 - 1.9e-05 25.2 0.0 0.0023 18.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXG50083.1 - 9.6e-05 22.6 0.0 0.022 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXG50083.1 - 0.00015 21.4 0.2 0.0071 15.9 0.1 2.7 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 KXG50083.1 - 0.00016 21.6 0.0 0.07 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXG50083.1 - 0.00026 20.7 0.4 0.011 15.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXG50083.1 - 0.00081 19.3 0.1 0.0029 17.5 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 KXG50083.1 - 0.0023 18.2 0.0 0.053 13.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 KXG50083.1 - 0.015 15.7 0.0 1.2 9.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXG50083.1 - 0.02 14.6 1.0 2.3 7.9 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXG50083.1 - 0.028 14.7 1.6 0.39 11.0 0.1 3.0 3 1 0 3 3 3 0 AAA domain SMC_N PF02463.19 KXG50083.1 - 0.036 13.5 0.0 1.2 8.6 0.0 2.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 KXG50083.1 - 0.038 13.6 2.0 0.22 11.1 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KXG50083.1 - 0.043 13.7 0.6 7 6.5 0.2 2.4 2 0 0 2 2 2 0 NACHT domain MbeD_MobD PF04899.12 KXG50083.1 - 0.15 12.2 0.1 0.39 10.9 0.1 1.7 1 0 0 1 1 1 0 MbeD/MobD like PduV-EutP PF10662.9 KXG50083.1 - 0.15 11.8 0.4 8.5 6.1 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 KXG50083.1 - 0.19 12.1 0.3 15 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXG50083.1 - 0.33 11.4 0.1 0.33 11.4 0.1 3.2 4 0 0 4 4 3 0 AAA domain Beta-lactamase PF00144.24 KXG50085.1 - 1.2e-60 205.5 0.0 1.6e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KXG50085.1 - 4.3e-15 56.0 0.0 8.4e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Beta-lactamase2 PF13354.6 KXG50085.1 - 0.18 11.4 0.0 0.48 10.0 0.0 1.6 2 0 0 2 2 2 0 Beta-lactamase enzyme family Pkinase PF00069.25 KXG50086.1 - 2.7e-10 40.1 0.3 1.5e-07 31.0 0.1 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG50086.1 - 4.8e-07 29.3 0.1 0.00054 19.3 0.0 2.9 2 1 1 3 3 3 2 Protein tyrosine kinase Glyco_hydro_2_C PF02836.17 KXG50087.1 - 9.8e-101 336.8 0.0 1.5e-100 336.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KXG50087.1 - 1.7e-57 194.9 0.0 4.8e-57 193.4 0.0 1.7 2 0 0 2 2 2 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KXG50087.1 - 1.3e-50 171.6 0.4 2.6e-50 170.6 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KXG50087.1 - 1.2e-12 48.1 0.4 6.3e-12 45.8 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KXG50087.1 - 5.8e-11 43.0 0.1 1.4e-10 41.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Fungal_trans PF04082.18 KXG50087.1 - 4.7e-10 38.9 3.7 2e-09 36.9 3.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG50087.1 - 3.4e-08 33.5 8.1 3.4e-08 33.5 8.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4660 PF15559.6 KXG50087.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) Sugar_tr PF00083.24 KXG50088.1 - 2e-85 287.3 29.2 2.3e-85 287.1 29.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG50088.1 - 2.4e-09 36.6 35.9 2.4e-09 36.6 35.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KXG50089.1 - 2e-22 79.6 25.1 3.9e-20 72.1 23.7 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Ribosomal_L19 PF01245.20 KXG50090.1 - 8e-16 58.0 1.6 1.4e-15 57.2 1.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 PriA_3primeBD PF17764.1 KXG50090.1 - 0.098 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 3′ DNA-binding domain (3′BD) GatD_N PF18195.1 KXG50090.1 - 0.16 11.3 0.1 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 GatD N-terminal domain AMP-binding PF00501.28 KXG50092.1 - 1.1e-12 47.3 0.1 6.3e-12 44.8 0.1 1.8 1 1 0 1 1 1 1 AMP-binding enzyme NPCC PF08058.11 KXG50093.1 - 9.1e-24 84.0 0.0 1.3e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex component CytochromB561_N PF09786.9 KXG50093.1 - 0.00012 21.2 1.7 0.00015 21.0 1.7 1.0 1 0 0 1 1 1 1 Cytochrome B561, N terminal Hid1 PF12722.7 KXG50094.1 - 0 1110.1 0.0 0 1110.0 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KXG50094.1 - 1.9e-100 337.1 0.0 2.3e-100 336.9 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DASH_Spc19 PF08287.11 KXG50094.1 - 0.09 12.7 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 Spc19 HAT_KAT11 PF08214.11 KXG50096.1 - 3.1e-107 358.9 0.0 4.9e-107 358.3 0.0 1.3 1 0 0 1 1 1 1 Histone acetylation protein Glyco_transf_21 PF13506.6 KXG50097.1 - 1.8e-14 53.6 0.2 9.7e-07 28.4 0.0 3.5 2 1 0 3 3 3 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KXG50097.1 - 5.2e-06 26.5 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXG50097.1 - 0.0026 17.6 0.0 0.0068 16.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Ank_2 PF12796.7 KXG50098.1 - 6.8e-14 52.2 1.0 4.4e-13 49.6 1.1 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG50098.1 - 6e-13 49.0 1.0 1.1e-08 35.5 0.1 2.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXG50098.1 - 5.7e-12 45.5 2.7 4e-08 33.4 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXG50098.1 - 1.5e-11 44.3 1.1 8.1e-10 38.8 0.9 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG50098.1 - 2.3e-09 36.7 0.1 2.3e-06 27.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat WW PF00397.26 KXG50099.1 - 1e-06 28.7 1.9 1e-06 28.7 1.9 2.0 2 0 0 2 2 2 1 WW domain WRW PF10206.9 KXG50099.1 - 0.0043 17.4 8.8 1 9.8 0.9 3.2 3 0 0 3 3 3 2 Mitochondrial F1F0-ATP synthase, subunit f DUF3801 PF12687.7 KXG50099.1 - 0.039 14.0 8.7 0.081 13.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Pet100 PF09803.9 KXG50099.1 - 6.9 7.3 6.5 0.94 10.0 1.9 2.0 2 0 0 2 2 2 0 Pet100 CFEM PF05730.11 KXG50100.1 - 3.8e-05 23.7 6.1 3.8e-05 23.7 6.1 2.3 2 0 0 2 2 2 1 CFEM domain Tme5_EGF_like PF09064.10 KXG50100.1 - 0.022 14.6 3.3 0.081 12.8 3.3 2.0 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like Hydrophobin PF01185.18 KXG50101.1 - 4.8e-09 36.7 5.7 6.9e-09 36.2 5.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin NMO PF03060.15 KXG50103.1 - 9.7e-55 186.2 0.8 1.9e-53 182.0 0.8 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXG50103.1 - 1e-13 51.1 0.0 3.2e-12 46.1 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXG50103.1 - 1.5e-05 24.2 0.4 2.6e-05 23.4 0.4 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KXG50103.1 - 0.031 13.7 0.1 0.22 11.0 0.0 2.0 2 1 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.14 KXG50103.1 - 0.032 13.4 0.1 0.052 12.7 0.1 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 KXG50103.1 - 0.045 12.9 0.5 0.11 11.7 0.5 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase Sdh_cyt PF01127.22 KXG50104.1 - 2.9e-24 85.4 5.0 3.7e-24 85.1 5.0 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF5337 PF17272.2 KXG50104.1 - 0.51 10.2 5.0 0.22 11.3 1.9 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Ribonucleas_3_3 PF14622.6 KXG50105.1 - 2.1e-28 99.0 0.0 3.7e-28 98.2 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXG50105.1 - 1.7e-06 28.6 0.0 4.6e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Adap_comp_sub PF00928.21 KXG50106.1 - 1.5e-90 303.2 0.0 2.2e-90 302.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXG50106.1 - 1e-08 35.2 0.2 1.7e-08 34.5 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KXG50106.1 - 0.12 11.8 0.0 0.34 10.3 0.0 1.6 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Ank_2 PF12796.7 KXG50107.1 - 1e-40 138.2 0.0 1.7e-10 41.3 0.0 5.5 5 1 0 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG50107.1 - 1.5e-27 95.6 0.0 0.0076 16.8 0.0 10.8 6 3 4 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG50107.1 - 1.1e-16 59.1 8.3 0.67 10.7 0.0 12.3 14 1 1 15 15 11 3 Ankyrin repeat NACHT PF05729.12 KXG50107.1 - 8e-11 42.1 0.0 1.9e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 NACHT domain Ank PF00023.30 KXG50107.1 - 1.5e-10 41.0 7.9 14 6.3 0.2 10.0 11 1 1 12 12 9 0 Ankyrin repeat Ank_5 PF13857.6 KXG50107.1 - 4.1e-10 39.7 9.2 0.11 12.9 0.2 7.8 5 3 3 8 8 8 4 Ankyrin repeats (many copies) AAA_16 PF13191.6 KXG50107.1 - 9.9e-06 26.0 0.1 4.9e-05 23.8 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KXG50107.1 - 3.7e-05 24.0 0.0 9.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXG50107.1 - 0.0014 19.0 0.0 0.0041 17.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 KXG50107.1 - 0.0078 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase KAP_NTPase PF07693.14 KXG50107.1 - 0.021 14.1 0.5 4.9 6.3 0.3 2.4 1 1 0 2 2 2 0 KAP family P-loop domain NACHT_N PF17100.5 KXG50107.1 - 0.057 13.3 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase AAA_19 PF13245.6 KXG50107.1 - 0.074 13.4 0.0 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXG50107.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Acetyltransf_7 PF13508.7 KXG50107.1 - 0.13 12.7 0.0 2.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain NB-ARC PF00931.22 KXG50107.1 - 0.14 11.3 0.0 0.35 10.0 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.6 KXG50107.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NmrA PF05368.13 KXG50108.1 - 5.2e-34 117.8 0.0 6.4e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG50108.1 - 2e-21 76.7 0.0 2.8e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXG50108.1 - 8e-07 28.8 0.0 8.7e-06 25.4 0.0 2.3 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXG50108.1 - 0.00054 19.2 0.0 0.037 13.2 0.0 2.4 1 1 1 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KXG50108.1 - 0.0035 16.8 0.0 0.021 14.2 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KXG50108.1 - 0.0075 16.5 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KXG50108.1 - 0.014 14.4 0.0 0.031 13.3 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pterin_bind PF00809.22 KXG50108.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Pterin binding enzyme AP_endonuc_2 PF01261.24 KXG50108.1 - 0.041 13.3 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Rogdi_lz PF10259.9 KXG50108.1 - 0.07 12.6 0.1 0.61 9.5 0.1 2.0 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein TrkA_N PF02254.18 KXG50108.1 - 0.12 12.7 0.0 0.45 10.8 0.0 2.0 2 1 0 2 2 2 0 TrkA-N domain Gtr1_RagA PF04670.12 KXG50109.1 - 2.6e-95 318.2 0.4 3.2e-95 317.9 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KXG50109.1 - 4.3e-09 36.6 0.0 8.4e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXG50109.1 - 1.7e-08 34.2 0.0 2.6e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KXG50109.1 - 1.8e-08 34.0 0.0 2.6e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXG50109.1 - 2.3e-07 30.9 0.0 4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KXG50109.1 - 0.00087 18.5 2.2 0.52 9.4 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 KXG50109.1 - 0.0015 18.5 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain DUF815 PF05673.13 KXG50109.1 - 0.009 15.2 0.1 0.019 14.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 KXG50109.1 - 0.013 15.3 0.3 0.058 13.1 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KXG50109.1 - 0.018 15.6 0.0 0.035 14.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.10 KXG50109.1 - 0.032 13.7 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KXG50109.1 - 0.042 13.8 0.3 0.37 10.7 0.0 2.5 3 0 0 3 3 3 0 RsgA GTPase AAA_7 PF12775.7 KXG50109.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AIG1 PF04548.16 KXG50109.1 - 0.33 10.2 1.5 0.47 9.8 0.4 2.0 2 1 0 2 2 2 0 AIG1 family DUF1688 PF07958.11 KXG50110.1 - 6.4e-182 605.0 0.0 7.3e-182 604.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) TPR_2 PF07719.17 KXG50111.1 - 6.5e-05 22.8 0.9 0.56 10.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXG50111.1 - 0.00057 19.6 0.2 6.6 6.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.31 KXG50111.1 - 0.0016 18.3 0.6 0.0033 17.3 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain TPR_12 PF13424.6 KXG50111.1 - 0.02 15.2 0.1 0.17 12.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.31 KXG50111.1 - 0.065 13.4 0.0 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 DnaJ domain GCD14 PF08704.10 KXG50112.1 - 8.8e-62 209.0 0.6 5.6e-61 206.3 0.0 2.3 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit tRNA-synt_1e PF01406.19 KXG50113.1 - 2.3e-114 381.8 0.0 3.7e-114 381.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KXG50113.1 - 1.5e-06 27.2 0.4 0.022 13.5 0.1 3.2 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 KXG50113.1 - 0.0057 17.1 1.7 0.0074 16.7 0.0 2.2 2 0 0 2 2 2 1 DALR domain SAGA-Tad1 PF12767.7 KXG50113.1 - 0.27 11.0 2.3 0.48 10.1 2.3 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Pinin_SDK_memA PF04696.13 KXG50113.1 - 1.6 8.8 15.2 3 7.9 15.2 1.5 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region TAL_FSA PF00923.19 KXG50114.1 - 2.1e-43 148.7 0.0 3e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase PQ-loop PF04193.14 KXG50114.1 - 1.1e-39 134.0 11.4 1.3e-20 72.9 2.1 2.6 2 0 0 2 2 2 2 PQ loop repeat Cas9-BH PF16593.5 KXG50114.1 - 0.014 15.1 5.0 0.032 13.9 5.0 1.5 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 HTH_Bact PF18768.1 KXG50114.1 - 0.23 11.1 0.5 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix bacterial domain Melibiase_C PF17801.1 KXG50115.1 - 0.051 13.6 0.6 6.3 6.9 0.0 3.0 3 0 0 3 3 3 0 Alpha galactosidase C-terminal beta sandwich domain SQHop_cyclase_C PF13243.6 KXG50116.1 - 7.2e-49 166.6 0.3 4.2e-47 160.8 0.4 2.6 2 1 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KXG50116.1 - 9.8e-45 152.9 1.9 1.7e-40 138.9 0.3 3.2 4 0 0 4 4 4 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KXG50116.1 - 2.1e-30 104.1 5.7 1.8e-08 33.9 0.3 5.1 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat SGS PF05002.15 KXG50116.1 - 3e-27 94.5 0.6 9e-27 93.0 0.6 1.9 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KXG50116.1 - 1.6e-05 25.8 0.2 0.0087 17.1 0.0 2.4 1 1 1 2 2 2 2 CS domain Pec_lyase PF09492.10 KXG50116.1 - 0.0021 17.4 0.2 2.4 7.4 0.0 3.5 2 1 2 4 4 4 2 Pectic acid lyase TPR_2 PF07719.17 KXG50116.1 - 3.4 8.0 4.9 54 4.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TP6A_N PF04406.14 KXG50117.1 - 7.8e-20 70.6 0.2 1.3e-19 69.9 0.2 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase UQ_con PF00179.26 KXG50118.1 - 7.4e-50 168.2 0.0 8.4e-50 168.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Scramblase PF03803.15 KXG50119.1 - 2.6e-56 190.4 0.5 1.2e-29 103.2 0.0 3.0 2 1 0 2 2 2 2 Scramblase Ribosomal_L27 PF01016.19 KXG50121.1 - 4.5e-28 97.1 0.0 7.4e-28 96.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein GMC_oxred_N PF00732.19 KXG50122.1 - 2.3e-52 178.2 0.0 3.1e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG50122.1 - 5.3e-43 147.0 0.0 9.5e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXG50122.1 - 6.7e-05 23.0 0.5 0.0002 21.5 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG50122.1 - 9.5e-05 21.8 0.0 0.00024 20.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG50122.1 - 0.00023 20.4 0.1 0.0009 18.4 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXG50122.1 - 0.0014 18.3 0.7 0.0031 17.1 0.4 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXG50122.1 - 0.002 17.2 0.1 0.003 16.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KXG50122.1 - 0.019 14.1 0.3 0.042 12.9 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KXG50122.1 - 0.023 13.4 0.1 0.042 12.6 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KXG50122.1 - 0.036 13.3 0.0 8.9 5.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG50122.1 - 0.075 12.3 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KXG50122.1 - 0.13 11.6 0.5 0.22 10.8 0.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXG50122.1 - 0.23 10.3 0.4 0.38 9.5 0.4 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Ysc84 PF04366.12 KXG50123.1 - 1.3e-38 131.6 0.5 2.7e-38 130.6 0.5 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator TspO_MBR PF03073.15 KXG50124.1 - 1.5e-43 148.1 9.9 2.2e-43 147.5 9.9 1.3 1 0 0 1 1 1 1 TspO/MBR family Rad9_Rad53_bind PF08605.10 KXG50124.1 - 1.1e-29 103.3 0.0 1.8e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding Tudor_3 PF18115.1 KXG50124.1 - 3.2e-17 62.1 0.0 6.3e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain BRCT_2 PF16589.5 KXG50124.1 - 3.8e-08 33.6 0.0 1.5e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KXG50124.1 - 1.7e-07 31.5 0.0 5.8e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KXG50124.1 - 0.004 17.0 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KXG50124.1 - 0.16 12.1 0.0 7.5 6.7 0.0 2.7 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain tRNA_int_endo PF01974.17 KXG50125.1 - 3.4e-18 65.5 0.7 1.3e-17 63.6 0.7 1.9 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KXG50125.1 - 1.5e-05 24.6 0.0 0.014 15.1 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain MMR1 PF08505.10 KXG50125.1 - 0.88 9.8 6.7 1.4 9.2 6.7 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Nop10p PF04135.12 KXG50126.1 - 4.3e-22 77.9 0.4 5.4e-22 77.6 0.4 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family PIN_6 PF17146.4 KXG50127.1 - 8.7e-31 106.3 0.9 2.9e-30 104.6 0.0 2.2 2 0 0 2 2 2 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 KXG50127.1 - 2.6e-30 104.4 3.5 4.7e-30 103.6 3.5 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_15 PF17032.5 KXG50127.1 - 0.028 15.2 0.4 0.055 14.2 0.4 1.5 1 0 0 1 1 1 0 zinc-ribbon family zf-NADH-PPase PF09297.11 KXG50127.1 - 0.078 12.6 1.6 0.39 10.4 0.2 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain SDA1 PF05285.12 KXG50127.1 - 6.7 6.0 15.7 2.5 7.5 13.3 1.4 1 1 0 1 1 1 0 SDA1 Zn-ribbon_8 PF09723.10 KXG50127.1 - 6.7 6.9 5.9 1 9.5 1.3 2.1 2 0 0 2 2 2 0 Zinc ribbon domain DUF2448 PF10476.9 KXG50128.1 - 0.0082 16.0 1.9 0.019 14.8 1.9 1.6 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2448) DUF3995 PF13160.6 KXG50128.1 - 1.3 9.4 11.2 4 7.8 1.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) Peptidase_M18 PF02127.15 KXG50129.1 - 1.7e-136 455.5 0.0 2e-136 455.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KXG50129.1 - 0.042 12.9 0.1 1.1 8.2 0.0 2.3 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase ADH_N PF08240.12 KXG50130.1 - 4.8e-19 68.2 0.3 1.3e-18 66.9 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KXG50130.1 - 7.9e-05 22.5 1.0 7.9e-05 22.5 1.0 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 KXG50130.1 - 0.0043 16.5 0.3 0.034 13.6 0.0 2.2 3 0 0 3 3 3 1 Glucose dehydrogenase C-terminus Hap4_Hap_bind PF10297.9 KXG50131.1 - 1.1e-08 34.8 6.9 1.1e-08 34.8 6.9 2.4 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KXG50131.1 - 3.8e-07 30.1 8.9 3.7e-05 23.7 11.0 2.2 1 1 1 2 2 2 1 bZIP transcription factor Filament PF00038.21 KXG50131.1 - 0.027 14.0 3.3 0.044 13.4 3.3 1.3 1 0 0 1 1 1 0 Intermediate filament protein bZIP_2 PF07716.15 KXG50131.1 - 0.039 14.0 10.5 0.13 12.4 10.5 1.8 1 1 0 1 1 1 0 Basic region leucine zipper DUF812 PF05667.11 KXG50131.1 - 0.071 12.0 2.3 0.11 11.4 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) dsrm PF00035.26 KXG50131.1 - 0.088 13.5 0.0 0.29 11.9 0.0 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding motif Tropomyosin_1 PF12718.7 KXG50131.1 - 0.097 12.8 2.8 0.17 12.1 2.8 1.3 1 0 0 1 1 1 0 Tropomyosin like FlaC_arch PF05377.11 KXG50131.1 - 0.23 11.9 0.4 0.44 11.0 0.4 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF2353 PF09789.9 KXG50131.1 - 0.33 10.3 2.8 0.48 9.7 2.8 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Jnk-SapK_ap_N PF09744.9 KXG50131.1 - 2 8.6 6.6 3.2 7.9 6.6 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 bZIP_Maf PF03131.17 KXG50131.1 - 3.7 8.1 10.1 0.69 10.5 6.1 1.9 2 1 0 2 2 1 0 bZIP Maf transcription factor SRP54 PF00448.22 KXG50132.1 - 3.1e-75 252.1 2.6 5.7e-75 251.3 2.6 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KXG50132.1 - 4.3e-29 101.0 0.4 4.3e-29 101.0 0.4 4.2 4 1 0 4 4 2 1 Signal peptide binding domain SRP54_N PF02881.19 KXG50132.1 - 7.4e-20 71.0 0.5 1.8e-19 69.7 0.5 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KXG50132.1 - 8.6e-08 32.0 0.2 2.4e-07 30.5 0.2 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KXG50132.1 - 8.5e-06 26.0 0.1 2.4e-05 24.6 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KXG50132.1 - 1.5e-05 25.4 1.3 3.1e-05 24.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXG50132.1 - 1.7e-05 25.3 0.1 3.7e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KXG50132.1 - 0.00023 20.5 0.1 0.00052 19.3 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 KXG50132.1 - 0.00031 19.8 0.3 0.00031 19.8 0.3 2.6 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 KXG50132.1 - 0.001 19.0 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_30 PF13604.6 KXG50132.1 - 0.001 18.8 0.7 0.0033 17.2 0.4 2.1 2 0 0 2 2 1 1 AAA domain CbiA PF01656.23 KXG50132.1 - 0.0022 18.1 0.0 0.0067 16.5 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 KXG50132.1 - 0.0037 17.3 0.6 0.012 15.6 0.6 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit 6PF2K PF01591.18 KXG50132.1 - 0.004 16.5 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase SRPRB PF09439.10 KXG50132.1 - 0.0045 16.4 1.5 1.6 8.1 1.0 3.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KXG50132.1 - 0.0046 17.0 0.2 0.049 13.7 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KXG50132.1 - 0.005 17.1 0.0 0.016 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 KXG50132.1 - 0.005 16.7 0.5 0.014 15.1 0.1 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 KXG50132.1 - 0.0068 16.7 0.1 0.015 15.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXG50132.1 - 0.0069 16.9 0.0 0.018 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KXG50132.1 - 0.0079 15.9 0.1 0.027 14.1 0.1 1.9 1 0 0 1 1 1 1 Thymidylate kinase MobB PF03205.14 KXG50132.1 - 0.01 15.7 0.0 0.032 14.1 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.6 KXG50132.1 - 0.03 14.3 0.4 0.25 11.2 0.3 2.2 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 KXG50132.1 - 0.075 13.4 0.3 0.2 12.0 0.3 1.7 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KXG50132.1 - 0.087 12.3 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 1 0 ADP-ribosylation factor family AAA_24 PF13479.6 KXG50132.1 - 0.092 12.4 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXG50132.1 - 0.099 13.2 0.7 0.6 10.6 0.0 2.2 2 1 0 2 2 2 0 ABC transporter MipZ PF09140.11 KXG50132.1 - 0.12 11.6 0.6 2.1 7.6 0.6 2.3 1 1 0 1 1 1 0 ATPase MipZ AAA PF00004.29 KXG50132.1 - 0.15 12.5 0.4 0.44 11.0 0.4 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GET2 PF08690.10 KXG50132.1 - 0.84 9.3 6.6 1.6 8.4 6.6 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 Rrp15p PF07890.12 KXG50133.1 - 3.5e-36 124.5 4.4 3.5e-36 124.5 4.4 2.0 2 1 0 2 2 2 1 Rrp15p Fer2 PF00111.27 KXG50134.1 - 2.3e-14 53.1 1.1 3.3e-14 52.6 1.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.27 KXG50135.1 - 2.6e-12 46.5 5.4 0.00058 19.7 0.0 4.8 3 2 0 3 3 3 3 Mitochondrial carrier protein PhoD PF09423.10 KXG50136.1 - 3.7e-37 128.2 0.0 7.9e-37 127.1 0.0 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 KXG50136.1 - 0.00044 20.8 0.3 0.0013 19.3 0.3 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 KXG50136.1 - 0.041 14.2 1.1 0.23 11.8 0.7 2.4 2 0 0 2 2 2 0 Fibronectin type III domain DcuC PF03606.15 KXG50136.1 - 0.094 11.1 0.1 0.13 10.6 0.1 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier PhoD_N PF16655.5 KXG50136.1 - 0.13 12.8 0.5 0.63 10.6 0.3 2.3 1 1 1 2 2 2 0 PhoD-like phosphatase, N-terminal domain Glyco_hydro_18 PF00704.28 KXG50137.1 - 3.3e-15 56.6 0.0 4.8e-15 56.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Fez1 PF06818.15 KXG50138.1 - 0.00016 22.2 15.3 0.00016 22.2 15.3 4.6 4 1 1 5 5 5 2 Fez1 DivIC PF04977.15 KXG50138.1 - 0.0071 16.1 5.0 0.0071 16.1 5.0 8.7 4 4 5 9 9 9 3 Septum formation initiator RMMBL PF07521.12 KXG50138.1 - 0.014 15.4 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain BRE1 PF08647.11 KXG50138.1 - 0.014 15.4 10.2 0.014 15.4 10.2 6.3 3 2 2 5 5 5 0 BRE1 E3 ubiquitin ligase bZIP_2 PF07716.15 KXG50138.1 - 0.078 13.1 0.4 0.078 13.1 0.4 7.7 5 3 3 8 8 8 0 Basic region leucine zipper AbiGi PF10899.8 KXG50138.1 - 0.66 9.8 3.9 7.6 6.3 0.1 2.6 2 0 0 2 2 2 0 Putative abortive phage resistance protein AbiGi, antitoxin Goodbye PF17109.5 KXG50139.1 - 4.2e-30 104.7 0.0 1.7e-29 102.7 0.0 2.1 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain AAA_16 PF13191.6 KXG50139.1 - 0.00031 21.2 0.0 0.0019 18.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain TPR_8 PF13181.6 KXG50139.1 - 0.00058 19.9 1.7 8.8 6.8 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXG50139.1 - 0.0006 20.0 3.8 11 6.4 0.1 4.8 3 1 1 4 4 4 0 Tetratricopeptide repeat NACHT PF05729.12 KXG50139.1 - 0.0015 18.5 0.2 0.02 14.8 0.0 3.1 3 0 0 3 3 3 1 NACHT domain TPR_14 PF13428.6 KXG50139.1 - 0.0017 19.0 0.2 13 7.0 0.0 4.5 5 0 0 5 5 3 0 Tetratricopeptide repeat AAA_24 PF13479.6 KXG50139.1 - 0.0036 17.0 0.0 0.045 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain TPR_10 PF13374.6 KXG50139.1 - 0.0053 16.6 0.1 3.9 7.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.6 KXG50139.1 - 0.0085 16.4 0.0 0.2 11.9 0.0 3.2 3 1 0 3 3 2 1 AAA domain DUF2075 PF09848.9 KXG50139.1 - 0.012 14.9 0.0 0.027 13.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TPR_7 PF13176.6 KXG50139.1 - 0.014 15.4 2.5 2.9 8.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RNA_helicase PF00910.22 KXG50139.1 - 0.016 15.6 0.0 0.073 13.5 0.0 2.2 1 0 0 1 1 1 0 RNA helicase TPR_19 PF14559.6 KXG50139.1 - 0.037 14.5 0.2 2.6 8.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_14 PF13173.6 KXG50139.1 - 0.086 12.9 0.0 0.28 11.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXG50139.1 - 0.11 12.3 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein TPR_1 PF00515.28 KXG50139.1 - 0.11 12.4 2.5 8.7 6.4 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXG50139.1 - 0.12 12.6 6.0 32 5.0 0.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXG50139.1 - 0.12 13.1 0.0 0.91 10.2 0.0 2.5 3 0 0 3 3 2 0 Tetratricopeptide repeat ResIII PF04851.15 KXG50139.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ZZ PF00569.17 KXG50139.1 - 6.7 6.6 9.7 0.51 10.2 4.3 2.0 2 0 0 2 2 2 0 Zinc finger, ZZ type Internalin_N PF12354.8 KXG50140.1 - 0.52 10.4 1.5 8.1 6.6 0.1 3.0 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal Ribonuc_L-PSP PF01042.21 KXG50141.1 - 2.6e-37 127.5 0.0 2.8e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DsbB PF02600.16 KXG50141.1 - 0.066 13.6 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Disulfide bond formation protein DsbB API5 PF05918.11 KXG50141.1 - 0.1 11.4 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Abhydrolase_3 PF07859.13 KXG50142.1 - 5.3e-67 225.8 0.0 6.9e-67 225.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXG50142.1 - 2.4e-11 43.5 0.0 3.5e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KXG50142.1 - 7.4e-08 31.7 0.2 1.7e-07 30.5 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KXG50142.1 - 1.2e-05 24.4 0.0 2.7e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 KXG50142.1 - 0.019 13.9 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme AA_permease_2 PF13520.6 KXG50143.1 - 4.9e-46 157.4 38.1 1.2e-38 133.1 30.4 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KXG50143.1 - 7.6e-09 34.7 24.4 7.6e-09 34.7 24.4 1.9 2 0 0 2 2 2 1 Amino acid permease MFS_1 PF07690.16 KXG50144.1 - 4e-21 75.3 28.6 4e-21 75.3 28.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.6 KXG50144.1 - 0.097 12.3 0.1 0.097 12.3 0.1 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4131) DUF2397 PF09660.10 KXG50145.1 - 0.0018 17.3 3.1 0.0059 15.6 1.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2397) Flagellar_rod PF05149.12 KXG50145.1 - 0.34 10.3 4.7 5.7 6.3 0.2 2.1 2 0 0 2 2 2 0 Paraflagellar rod protein Pkinase PF00069.25 KXG50146.1 - 1.7e-61 207.9 0.0 2.7e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG50146.1 - 4e-39 134.5 0.0 5.9e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG50146.1 - 9.9e-08 31.6 0.0 3e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXG50146.1 - 0.0011 18.4 0.1 0.0019 17.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KXG50146.1 - 0.013 15.0 0.3 0.067 12.7 0.0 2.1 1 1 0 2 2 2 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KXG50146.1 - 0.017 14.7 0.0 0.066 12.8 0.0 1.8 1 1 1 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KXG50146.1 - 0.48 9.1 8.7 1.2 7.9 8.7 1.7 1 1 0 1 1 1 0 Fungal protein kinase Glyco_hydro_18 PF00704.28 KXG50147.1 - 3.1e-20 73.1 0.2 1e-19 71.4 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CoA_transf_3 PF02515.17 KXG50148.1 - 1.7e-68 231.4 0.0 6.7e-68 229.5 0.0 1.7 1 1 0 1 1 1 1 CoA-transferase family III GMC_oxred_N PF00732.19 KXG50149.1 - 2.9e-60 204.1 0.0 4.1e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG50149.1 - 5.5e-32 111.3 0.0 1.1e-31 110.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXG50149.1 - 0.00033 20.8 0.2 0.0011 19.1 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXG50149.1 - 0.00068 18.8 0.2 0.089 11.9 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXG50149.1 - 0.00077 18.8 0.1 0.12 11.6 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG50149.1 - 0.014 14.7 0.1 0.074 12.3 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXG50149.1 - 0.024 13.7 0.0 0.047 12.7 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein GFO_IDH_MocA PF01408.22 KXG50149.1 - 0.066 14.1 0.0 0.13 13.1 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Aminotran_3 PF00202.21 KXG50150.1 - 5.2e-80 269.1 0.0 6.4e-80 268.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans PF04082.18 KXG50151.1 - 1.6e-16 60.1 1.0 6.9e-16 58.1 1.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain TauD PF02668.16 KXG50152.1 - 2.2e-48 165.4 0.7 3.2e-48 164.9 0.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NOG1 PF06858.14 KXG50152.1 - 0.014 15.2 0.2 0.095 12.5 0.0 2.2 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) MFS_1 PF07690.16 KXG50153.1 - 2.1e-09 36.8 24.0 2.1e-09 36.8 24.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXG50153.1 - 1.6e-06 27.9 1.1 1.6e-06 27.9 1.1 2.5 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 SDF PF00375.18 KXG50153.1 - 0.011 14.8 0.0 0.023 13.7 0.0 1.5 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family Sugar_tr PF00083.24 KXG50153.1 - 0.062 12.2 13.3 0.41 9.5 13.3 2.1 1 1 0 1 1 1 0 Sugar (and other) transporter Transketolase_N PF00456.21 KXG50154.1 - 1.1e-13 50.8 1.5 2.1e-12 46.6 1.5 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 KXG50154.1 - 7.8e-13 48.4 0.0 1.8e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KXG50154.1 - 4.7e-06 26.4 1.6 1.4e-05 24.9 0.3 2.1 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 KXG50154.1 - 0.0012 18.6 1.0 0.0069 16.2 1.0 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KXG50154.1 - 0.021 13.8 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component Glyco_hydro_30 PF02055.16 KXG50155.1 - 1.2e-34 119.8 4.7 1.8e-34 119.3 4.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 KXG50155.1 - 6.1e-09 36.0 0.1 1.3e-08 34.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 KXG50155.1 - 0.00021 20.6 3.0 0.00028 20.2 0.1 2.2 1 1 0 2 2 2 1 Glycosyl hydrolase family 59 ADH_zinc_N_2 PF13602.6 KXG50156.1 - 5.3e-20 72.8 0.0 1.1e-19 71.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXG50156.1 - 2.7e-14 53.2 0.0 5.2e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG50156.1 - 5.6e-07 29.4 0.1 2.8e-06 27.2 0.0 2.1 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 KXG50156.1 - 0.00013 22.4 0.0 0.00031 21.2 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KXG50156.1 - 0.005 16.0 0.1 0.0089 15.2 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.18 KXG50156.1 - 0.041 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.20 KXG50156.1 - 0.041 14.0 0.1 0.074 13.2 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus bZIP_1 PF00170.21 KXG50157.1 - 0.0072 16.4 12.2 0.022 14.9 12.2 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXG50157.1 - 0.011 15.8 11.1 0.032 14.3 11.1 1.7 1 0 0 1 1 1 0 Basic region leucine zipper HSDR_N PF04313.14 KXG50158.1 - 0.11 12.5 0.1 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Pyr_redox_2 PF07992.14 KXG50159.1 - 2.6e-44 151.6 0.1 3.2e-44 151.3 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG50159.1 - 4.3e-13 49.6 0.1 6.2e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG50159.1 - 2.4e-07 30.7 4.4 0.076 12.6 0.1 4.0 3 1 1 4 4 4 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXG50159.1 - 3.2e-05 24.0 0.3 0.053 13.5 0.0 3.3 2 1 1 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXG50159.1 - 0.00077 18.8 0.3 29 3.8 0.1 4.0 1 1 2 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXG50159.1 - 0.0093 15.1 2.3 2.1 7.4 0.1 3.7 4 0 0 4 4 4 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXG50159.1 - 0.015 14.4 0.2 1.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 KXG50159.1 - 0.033 12.9 0.6 1.8 7.2 0.0 3.1 4 0 0 4 4 4 0 HI0933-like protein K_oxygenase PF13434.6 KXG50159.1 - 0.079 12.1 0.0 0.28 10.3 0.0 1.8 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 KXG50159.1 - 0.2 10.7 2.0 1.9 7.5 0.1 3.0 4 0 0 4 4 4 0 FAD binding domain Fungal_trans PF04082.18 KXG50160.1 - 3.3e-08 32.9 1.0 8.4e-08 31.6 1.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Phage_connect_1 PF05135.13 KXG50160.1 - 0.047 14.2 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein Gly_transf_sug PF04488.15 KXG50162.1 - 4.1e-13 49.8 0.1 9.1e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Inhibitor_I66 PF16850.5 KXG50162.1 - 0.085 12.7 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Peptidase inhibitor I66 MFS_1 PF07690.16 KXG50163.1 - 5.4e-36 124.3 49.7 7.8e-35 120.4 31.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM100 PF16311.5 KXG50163.1 - 0.45 10.1 1.5 2.2 7.9 0.3 2.2 2 0 0 2 2 2 0 Transmembrane protein 100 DUF63 PF01889.17 KXG50163.1 - 0.47 10.6 7.5 0.062 13.5 2.8 1.9 2 0 0 2 2 2 0 Membrane protein of unknown function DUF63 RNA_pol_I_A49 PF06870.12 KXG50164.1 - 1.8e-66 224.6 0.0 4.3e-66 223.3 0.0 1.5 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor Aminotran_1_2 PF00155.21 KXG50165.1 - 5e-87 292.4 0.0 6.3e-87 292.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXG50165.1 - 3.2e-07 29.2 0.0 5.8e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXG50165.1 - 4.1e-05 23.1 0.2 9.3e-05 21.9 0.2 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KXG50165.1 - 8.3e-05 21.7 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXG50165.1 - 0.0067 15.7 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase 2Fe-2S_Ferredox PF11591.8 KXG50165.1 - 0.011 15.6 2.0 0.045 13.6 2.0 2.0 1 0 0 1 1 1 0 Ferredoxin chloroplastic transit peptide SNF2_N PF00176.23 KXG50166.1 - 6.5e-65 219.1 2.2 1.5e-64 218.0 2.2 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KXG50166.1 - 2.2e-49 167.3 22.0 2.2e-49 167.3 22.0 4.4 5 0 0 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 KXG50166.1 - 4.5e-19 68.8 0.0 1.2e-18 67.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG50166.1 - 1.1e-06 28.7 2.2 1.3e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXG50166.1 - 0.0041 16.9 0.0 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KXG50166.1 - 0.013 14.7 1.2 0.078 12.1 0.0 2.8 3 1 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 ADH_N PF08240.12 KXG50167.1 - 1.3e-27 95.9 0.3 2.2e-27 95.1 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG50167.1 - 6.6e-24 84.4 0.7 1.1e-23 83.6 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG50167.1 - 5.7e-05 24.2 0.2 8.9e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXG50167.1 - 0.0041 16.5 0.1 0.0072 15.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXG50167.1 - 0.022 14.0 0.7 0.033 13.5 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KXG50167.1 - 1.4 8.3 5.6 0.11 11.9 0.4 1.8 2 0 0 2 2 2 0 short chain dehydrogenase AA_permease_2 PF13520.6 KXG50168.1 - 1.4e-59 202.0 28.7 1.8e-59 201.7 28.7 1.0 1 0 0 1 1 1 1 Amino acid permease Na_H_Exchanger PF00999.21 KXG50169.1 - 3.5e-70 236.7 40.3 4.5e-70 236.4 40.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4396 PF14342.6 KXG50169.1 - 1.3 9.4 14.0 1.7 9.0 3.5 3.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4396) MFS_2 PF13347.6 KXG50170.1 - 2.4e-10 39.6 9.1 5.5e-10 38.4 9.1 1.5 1 0 0 1 1 1 1 MFS/sugar transport protein PUCC PF03209.15 KXG50170.1 - 3.4e-05 23.0 3.5 5.7e-05 22.3 3.5 1.3 1 0 0 1 1 1 1 PUCC protein STE PF02200.16 KXG50171.1 - 5.1e-55 184.6 0.0 7.8e-55 184.0 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KXG50171.1 - 2.5e-12 46.5 10.4 1.8e-06 28.0 0.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXG50171.1 - 9.4e-09 35.3 4.0 9.4e-09 35.3 4.0 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXG50171.1 - 1.2e-08 35.0 8.4 0.00091 19.9 0.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXG50171.1 - 0.00031 20.7 4.3 0.0015 18.5 0.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXG50171.1 - 0.0039 17.4 0.1 0.92 9.9 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 KXG50171.1 - 0.049 14.3 2.4 0.091 13.5 2.4 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-Di19 PF05605.12 KXG50171.1 - 0.12 12.7 3.0 0.32 11.3 3.0 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding NOA36 PF06524.12 KXG50171.1 - 0.12 11.7 0.2 0.19 11.0 0.2 1.2 1 0 0 1 1 1 0 NOA36 protein zf-C2HC_2 PF13913.6 KXG50171.1 - 0.15 12.0 5.4 1.9 8.5 0.3 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KXG50171.1 - 1.9 8.3 9.9 9.1 6.1 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain MFS_1 PF07690.16 KXG50172.1 - 3.7e-31 108.3 33.4 3.7e-31 108.3 33.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3007 PF11460.8 KXG50172.1 - 2.4 8.5 7.7 0.25 11.6 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Amidohydro_3 PF07969.11 KXG50174.1 - 4.2e-70 237.5 0.8 5e-70 237.3 0.8 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXG50174.1 - 3.3e-12 46.4 0.1 7e-06 25.6 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family SOG2 PF10428.9 KXG50175.1 - 0.41 9.8 16.9 0.44 9.7 16.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein QWRF PF04484.12 KXG50175.1 - 0.75 9.5 12.4 0.97 9.1 12.4 1.2 1 0 0 1 1 1 0 QWRF family Tmemb_cc2 PF10267.9 KXG50175.1 - 1.2 8.2 8.7 1.4 8.0 8.7 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Macoilin PF09726.9 KXG50175.1 - 1.2 7.6 13.9 1.3 7.5 13.9 1.1 1 0 0 1 1 1 0 Macoilin family Sec10 PF07393.11 KXG50175.1 - 2.1 6.7 4.0 2.6 6.4 4.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 SPX PF03105.19 KXG50175.1 - 4.1 7.2 14.3 5.2 6.9 14.3 1.1 1 0 0 1 1 1 0 SPX domain Myc_target_1 PF15179.6 KXG50178.1 - 0.044 13.7 1.1 8 6.3 0.0 2.5 2 1 0 2 2 2 0 Myc target protein 1 DUF455 PF04305.14 KXG50179.1 - 6.5e-100 333.8 0.0 8.1e-100 333.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 KXG50179.1 - 3.9e-07 29.9 0.0 7.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KXG50179.1 - 1.9e-06 27.8 0.0 5e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Abhydrolase_3 PF07859.13 KXG50181.1 - 5.4e-37 127.7 0.0 7.5e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXG50181.1 - 0.00039 19.4 0.1 0.0019 17.1 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family DLH PF01738.18 KXG50181.1 - 0.004 16.7 0.0 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KXG50181.1 - 0.0041 16.6 0.0 0.0064 16.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KXG50181.1 - 0.0044 16.9 0.0 0.0065 16.3 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 KXG50181.1 - 0.0053 15.5 0.0 0.0067 15.1 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Aminotran_3 PF00202.21 KXG50182.1 - 1.8e-83 280.5 0.0 2e-83 280.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aldedh PF00171.22 KXG50183.1 - 2.2e-167 557.2 0.2 2.5e-167 557.1 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1726 PF08351.11 KXG50183.1 - 0.086 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) HAD_2 PF13419.6 KXG50184.1 - 1.7e-10 41.3 0.0 5.6e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase AATase PF07247.12 KXG50185.1 - 2.5e-17 62.6 0.1 6e-15 54.8 0.1 2.8 1 1 0 1 1 1 1 Alcohol acetyltransferase Fungal_trans PF04082.18 KXG50186.1 - 1.9e-24 86.1 0.1 6.3e-24 84.4 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF5623 PF18536.1 KXG50186.1 - 0.092 13.0 0.4 15 5.9 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF5623) Chloroa_b-bind PF00504.21 KXG50186.1 - 0.099 13.2 0.0 0.32 11.5 0.0 1.8 2 0 0 2 2 2 0 Chlorophyll A-B binding protein Hamartin PF04388.12 KXG50187.1 - 0.66 8.6 10.4 0.96 8.0 10.4 1.2 1 0 0 1 1 1 0 Hamartin protein SOG2 PF10428.9 KXG50187.1 - 1.6 7.9 11.2 1.9 7.6 11.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ank_2 PF12796.7 KXG50188.1 - 1.6e-19 70.2 0.3 2.3e-07 31.3 0.0 5.2 5 1 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXG50188.1 - 2.5e-17 62.7 0.4 7.7e-08 32.5 0.0 5.6 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXG50188.1 - 3e-17 62.7 1.7 3.1e-05 24.4 0.0 5.8 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG50188.1 - 5e-16 57.2 0.2 0.014 15.9 0.0 7.0 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 KXG50188.1 - 2.9e-10 40.1 0.2 0.12 12.9 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat Oxidored_FMN PF00724.20 KXG50189.1 - 1.1e-63 215.6 0.0 1.4e-63 215.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 KXG50189.1 - 0.043 13.3 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein RNA_pol_Rpo13 PF12136.8 KXG50189.1 - 0.058 13.3 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain Dus PF01207.17 KXG50189.1 - 0.065 12.3 1.1 0.086 11.9 0.0 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KXG50189.1 - 0.066 12.4 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase FA_desaturase PF00487.24 KXG50190.1 - 2.1e-12 47.4 22.5 2.1e-12 47.4 22.5 1.9 1 1 1 2 2 2 1 Fatty acid desaturase RseC_MucC PF04246.12 KXG50190.1 - 0.1 12.5 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC SnoaL PF07366.12 KXG50191.1 - 0.00013 21.8 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXG50191.1 - 0.0034 18.0 0.0 0.009 16.6 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like domain NblA PF04485.12 KXG50192.1 - 0.024 15.0 0.0 0.1 13.0 0.1 1.9 2 0 0 2 2 2 0 Phycobilisome degradation protein nblA 2HCT PF03390.15 KXG50192.1 - 0.12 11.0 3.2 0.19 10.3 3.2 1.2 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family Abhydrolase_1 PF00561.20 KXG50193.1 - 6.9e-13 48.8 0.0 1.6e-12 47.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.8 KXG50194.1 - 5.1e-05 22.2 6.1 0.00035 19.5 6.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4246 PF14033.6 KXG50195.1 - 1e-123 413.8 0.0 1.3e-123 413.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Glyco_hydro_71 PF03659.14 KXG50197.1 - 8.9e-130 432.8 5.7 1.3e-129 432.3 5.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Isochorismatase PF00857.20 KXG50199.1 - 4e-21 76.0 0.0 6.7e-21 75.2 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family SDA1 PF05285.12 KXG50201.1 - 7.8 5.8 15.0 11 5.4 15.0 1.2 1 0 0 1 1 1 0 SDA1 CoA_binding PF02629.19 KXG50202.1 - 7e-26 90.8 1.0 4.4e-25 88.2 0.3 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KXG50202.1 - 1.8e-21 76.6 0.1 3e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KXG50202.1 - 6.5e-07 29.2 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KXG50202.1 - 0.013 16.0 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain Radical_SAM_C PF16199.5 KXG50203.1 - 1.5e-32 111.5 0.1 4.2e-32 110.0 0.0 1.8 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KXG50203.1 - 5e-20 72.5 0.0 2.7e-19 70.2 0.0 2.2 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KXG50203.1 - 3.4e-11 43.4 0.1 6.4e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXG50203.1 - 1.5e-05 24.9 0.1 6.8e-05 22.8 0.0 2.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Topoisom_bac PF01131.20 KXG50203.1 - 0.3 10.1 0.6 0.44 9.5 0.6 1.2 1 0 0 1 1 1 0 DNA topoisomerase MASE4 PF17158.4 KXG50204.1 - 0.025 13.8 1.2 3.2 7.0 0.0 2.0 2 0 0 2 2 2 0 Membrane-associated sensor, integral membrane domain Smim3 PF17307.2 KXG50204.1 - 1.4 8.5 4.6 4.7 6.8 0.2 2.2 2 0 0 2 2 2 0 Small integral membrane protein 3 DUF5310 PF17237.2 KXG50204.1 - 1.6 8.7 5.0 16 5.4 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5310) His_biosynth PF00977.21 KXG50205.1 - 3.5e-32 111.7 0.0 4.6e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF4602 PF15375.6 KXG50206.1 - 8.2e-12 45.6 15.0 1.9e-11 44.4 15.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) DUF4055 PF13264.6 KXG50206.1 - 0.19 11.9 0.9 5.4 7.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) Ribonuc_L-PSP PF01042.21 KXG50207.1 - 2.5e-20 72.7 0.0 3e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.16 KXG50208.1 - 1.2e-40 139.6 38.0 1.2e-40 139.6 38.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG50208.1 - 1.6e-08 33.9 15.9 1.6e-08 33.9 15.9 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KXG50208.1 - 4.7e-05 22.4 2.6 4.7e-05 22.4 2.6 2.2 2 0 0 2 2 2 1 MFS_1 like family OATP PF03137.20 KXG50208.1 - 0.024 12.9 8.8 0.29 9.4 0.6 2.7 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Methyltransf_10 PF05971.12 KXG50209.1 - 4e-66 223.4 0.0 5.1e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KXG50209.1 - 2.8e-07 30.3 0.0 5.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KXG50209.1 - 0.00028 20.4 0.0 0.00047 19.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 KXG50209.1 - 0.047 13.3 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_16 PF10294.9 KXG50209.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase UPF0020 PF01170.18 KXG50209.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 KXG50209.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Cellulase PF00150.18 KXG50210.1 - 3.1e-31 108.9 2.2 8.9e-31 107.3 1.6 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) TPR_2 PF07719.17 KXG50210.1 - 1.4e-05 24.8 5.3 0.031 14.4 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXG50210.1 - 0.0015 18.3 6.7 0.45 10.4 0.0 4.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXG50210.1 - 0.017 14.8 0.1 8.7 6.1 0.1 3.5 2 1 1 3 3 3 0 TPR repeat Pro_dh-DNA_bdg PF14850.6 KXG50210.1 - 0.033 14.7 0.0 0.1 13.1 0.0 1.9 1 0 0 1 1 1 0 DNA-binding domain of Proline dehydrogenase ANAPC3 PF12895.7 KXG50210.1 - 0.063 13.5 0.7 0.27 11.5 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KXG50210.1 - 0.12 12.4 2.3 4.1 7.7 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXG50210.1 - 0.16 12.4 0.0 12 6.5 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXG50210.1 - 2.4 8.7 13.3 0.77 10.3 0.1 4.7 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXG50210.1 - 4.5 7.7 6.1 79 3.9 0.3 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Ank_4 PF13637.6 KXG50211.1 - 1.6e-10 41.3 0.3 2.7e-07 31.0 0.1 4.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXG50211.1 - 7.7e-05 23.2 0.0 0.065 13.8 0.0 3.1 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXG50211.1 - 0.0017 18.6 0.4 0.11 12.9 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG50211.1 - 0.0022 18.4 1.7 1 10.2 0.1 3.8 3 1 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.13 KXG50211.1 - 0.0033 17.3 0.4 0.025 14.4 0.4 2.3 1 1 0 1 1 1 1 KilA-N domain Baculo_PEP_C PF04513.12 KXG50211.1 - 0.084 12.9 0.4 0.23 11.5 0.1 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rick_17kDa_Anti PF05433.15 KXG50213.1 - 0.00066 19.5 14.7 0.00066 19.5 14.7 1.8 2 0 0 2 2 2 1 Glycine zipper 2TM domain Dehydrin PF00257.19 KXG50213.1 - 0.0088 16.6 11.2 0.0094 16.5 10.9 1.4 1 1 0 1 1 1 1 Dehydrin SNARE_assoc PF09335.11 KXG50213.1 - 0.095 13.2 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 SNARE associated Golgi protein DUF533 PF04391.12 KXG50213.1 - 0.11 12.1 3.6 0.19 11.3 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DUF755 PF05501.11 KXG50213.1 - 0.31 11.3 18.4 0.41 10.9 18.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AP3D1 PF06375.11 KXG50213.1 - 2.3 8.4 14.8 3 8.0 14.8 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Sugar_tr PF00083.24 KXG50214.1 - 1.2e-38 133.2 15.0 4.4e-38 131.3 15.0 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG50214.1 - 6.2e-32 110.9 36.1 2.9e-30 105.4 23.0 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_9_N PF15420.6 KXG50214.1 - 0.029 14.4 0.5 0.029 14.4 0.5 2.6 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus Abhydrolase_6 PF12697.7 KXG50215.1 - 1.1e-09 39.2 0.4 1.6e-09 38.7 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG50215.1 - 2.8e-09 37.0 1.2 1.1e-08 35.0 0.3 2.3 3 1 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG50215.1 - 1.7e-07 30.7 0.1 4.6e-07 29.4 0.1 1.8 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Epimerase PF01370.21 KXG50216.1 - 2.3e-15 56.7 0.1 1e-14 54.6 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXG50216.1 - 1.2e-13 50.8 0.0 2.5e-13 49.7 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXG50216.1 - 2.6e-09 37.2 0.0 4.5e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXG50216.1 - 6.2e-09 35.7 0.0 4e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXG50216.1 - 3.9e-08 32.8 0.0 2.4e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KXG50216.1 - 5.4e-06 25.7 0.0 9.4e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KXG50216.1 - 0.00027 20.6 0.0 0.00047 19.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KXG50216.1 - 0.00036 20.0 0.0 0.00093 18.7 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase F420_oxidored PF03807.17 KXG50216.1 - 0.12 13.0 0.0 0.39 11.3 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KXG50216.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KXG50216.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Fungal_trans_2 PF11951.8 KXG50217.1 - 4e-06 25.9 0.1 6.3e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KXG50218.1 - 5.3e-11 42.1 2.5 1.1e-10 41.1 2.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2573 PF10835.8 KXG50218.1 - 0.13 12.6 0.0 0.43 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2573) PALP PF00291.25 KXG50219.1 - 2.3e-62 211.1 0.2 2.8e-62 210.8 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PG_isomerase_N PF18353.1 KXG50219.1 - 0.038 14.4 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucose isomerase N-terminal domain GFA PF04828.14 KXG50220.1 - 1.4e-18 67.0 0.2 1.4e-18 67.0 0.2 1.9 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PGAP1 PF07819.13 KXG50221.1 - 9e-90 300.4 0.0 1.5e-89 299.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KXG50221.1 - 9.4e-07 29.6 0.2 2.3e-06 28.4 0.2 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG50221.1 - 0.00036 20.3 0.4 0.0014 18.3 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 KXG50221.1 - 0.00045 20.1 0.0 0.00094 19.1 0.0 1.6 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 KXG50221.1 - 0.0079 15.5 0.0 0.019 14.3 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LCAT PF02450.15 KXG50221.1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Esterase PF00756.20 KXG50221.1 - 0.014 15.1 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Putative esterase DUF676 PF05057.14 KXG50221.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) ABC_tran PF00005.27 KXG50222.1 - 3.5e-46 157.1 0.1 9.5e-24 84.5 0.0 3.4 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 KXG50222.1 - 7.9e-30 102.8 1.3 2.2e-29 101.3 1.3 1.9 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 KXG50222.1 - 1e-14 55.1 0.1 0.0023 17.8 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXG50222.1 - 4.9e-13 49.0 0.1 0.00014 21.4 0.0 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXG50222.1 - 1.2e-09 39.0 0.0 0.0013 19.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXG50222.1 - 3.2e-08 34.0 0.0 0.0058 16.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXG50222.1 - 4.7e-08 32.6 0.1 0.009 15.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain PduV-EutP PF10662.9 KXG50222.1 - 1.4e-06 28.1 0.0 0.054 13.2 0.0 2.8 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KXG50222.1 - 6.3e-06 26.3 0.0 0.0042 17.2 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXG50222.1 - 7.4e-06 26.0 0.0 0.0078 16.1 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KXG50222.1 - 1.1e-05 25.7 0.0 0.029 14.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 KXG50222.1 - 1.2e-05 25.8 0.2 0.27 11.6 0.0 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 KXG50222.1 - 1.3e-05 25.7 0.0 0.091 13.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KXG50222.1 - 9e-05 22.8 0.0 0.46 10.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase DUF87 PF01935.17 KXG50222.1 - 0.00014 22.0 0.6 0.065 13.3 0.3 3.0 3 0 0 3 3 2 1 Helicase HerA, central domain Dynamin_N PF00350.23 KXG50222.1 - 0.00015 21.9 0.0 0.001 19.2 0.0 2.5 3 0 0 3 3 2 1 Dynamin family G-alpha PF00503.20 KXG50222.1 - 0.00016 21.0 0.1 0.57 9.3 0.0 2.7 2 1 0 2 2 2 2 G-protein alpha subunit NACHT PF05729.12 KXG50222.1 - 0.00017 21.6 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 KXG50222.1 - 0.00021 21.3 0.0 0.35 10.9 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 KXG50222.1 - 0.00026 21.4 0.0 0.2 12.1 0.0 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KXG50222.1 - 0.00028 20.7 0.0 1.1 8.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain NB-ARC PF00931.22 KXG50222.1 - 0.0008 18.7 0.1 0.016 14.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 KXG50222.1 - 0.00094 19.4 0.0 1.9 8.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KXG50222.1 - 0.0014 18.2 0.4 0.72 9.4 0.0 3.6 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KXG50222.1 - 0.0016 18.2 0.1 0.99 9.1 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_13 PF13166.6 KXG50222.1 - 0.0019 17.0 0.0 0.37 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KXG50222.1 - 0.002 17.8 0.1 0.43 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KXG50222.1 - 0.002 17.1 0.2 0.84 8.6 0.1 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KXG50222.1 - 0.002 17.9 0.0 1.5 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXG50222.1 - 0.0055 16.3 0.0 3.9 7.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KXG50222.1 - 0.0073 16.5 0.0 2.1 8.6 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Roc PF08477.13 KXG50222.1 - 0.0098 16.1 0.0 5.5 7.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KXG50222.1 - 0.018 14.9 0.0 6.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MukB PF04310.12 KXG50222.1 - 0.02 14.7 0.0 5.6 6.7 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_5 PF07728.14 KXG50222.1 - 0.025 14.6 0.0 7.8 6.5 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Septin PF00735.18 KXG50222.1 - 0.03 13.6 0.4 2.8 7.1 0.0 2.9 3 0 0 3 3 3 0 Septin ATP-synt_ab PF00006.25 KXG50222.1 - 0.031 13.9 0.0 3 7.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 KXG50222.1 - 0.044 13.3 0.1 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KXG50222.1 - 0.049 13.5 0.0 0.67 9.8 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KXG50222.1 - 0.051 13.6 0.0 7.4 6.6 0.0 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Arf PF00025.21 KXG50222.1 - 0.065 12.7 0.1 6.6 6.2 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family PRK PF00485.18 KXG50222.1 - 0.072 12.8 0.0 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 KXG50222.1 - 0.096 12.6 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CLP1_P PF16575.5 KXG50222.1 - 0.098 12.4 0.6 3.8 7.3 0.0 3.0 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop FtsK_SpoIIIE PF01580.18 KXG50222.1 - 0.1 11.9 0.4 0.52 9.6 0.1 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 KXG50222.1 - 0.12 11.8 0.0 13 5.1 0.0 2.8 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI Helicase_C PF00271.31 KXG50223.1 - 1.7e-12 47.6 0.0 3.7e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG50223.1 - 6.9e-10 39.2 0.0 3.4e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWIRM PF04433.17 KXG50225.1 - 6.8e-32 109.7 0.1 2e-31 108.2 0.1 1.9 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KXG50225.1 - 1.9e-31 107.8 13.0 4.1e-31 106.8 13.0 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KXG50225.1 - 8.2e-09 35.5 0.1 1.8e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXG50225.1 - 6.2e-06 26.4 0.1 1.5e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Mei5 PF10376.9 KXG50225.1 - 0.091 12.6 4.5 0.18 11.6 4.5 1.4 1 0 0 1 1 1 0 Double-strand recombination repair protein AAA_9 PF12781.7 KXG50225.1 - 0.25 10.4 2.4 0.47 9.6 2.4 1.3 1 0 0 1 1 1 0 ATP-binding dynein motor region DUF883 PF05957.13 KXG50225.1 - 0.34 11.5 9.8 0.28 11.8 3.8 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Myb_DNA-bind_7 PF15963.5 KXG50225.1 - 1.1 9.2 0.0 1.1 9.2 0.0 2.8 3 0 0 3 3 3 0 Myb DNA-binding like ZZ PF00569.17 KXG50225.1 - 1.6 8.6 6.0 13 5.6 6.0 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type DUF1996 PF09362.10 KXG50227.1 - 4.2e-45 154.6 0.5 5.1e-45 154.3 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Metallophos PF00149.28 KXG50228.1 - 1.2e-09 38.9 0.0 1.8e-09 38.4 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXG50228.1 - 5.4e-05 23.4 0.0 0.00016 21.9 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 KXG50229.1 - 6.5e-09 35.5 0.0 7.9e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXG50229.1 - 2.1e-05 24.6 0.1 3e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXG50229.1 - 0.00012 21.5 0.1 0.00018 20.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXG50229.1 - 0.00047 19.5 0.3 0.00085 18.7 0.3 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXG50229.1 - 0.0024 16.7 0.0 0.0031 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KXG50229.1 - 0.0073 15.9 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase WaaY PF06176.11 KXG50229.1 - 0.2 11.2 0.1 0.32 10.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Zip PF02535.22 KXG50230.1 - 0.34 10.1 0.7 0.33 10.1 0.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2183 PF09949.9 KXG50231.1 - 1.2e-21 76.9 0.1 2.6e-21 75.8 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF3732 PF12532.8 KXG50232.1 - 0.0033 17.0 0.2 0.0051 16.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3732) Sod_Fe_C PF02777.18 KXG50232.1 - 0.031 14.4 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, C-terminal domain Epimerase PF01370.21 KXG50232.1 - 0.042 13.3 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ank_2 PF12796.7 KXG50233.1 - 6.2e-36 122.8 1.7 1.1e-13 51.6 0.3 4.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG50233.1 - 2.6e-33 113.9 2.5 1.1e-08 35.4 0.0 6.4 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG50233.1 - 8.5e-28 96.1 5.6 6.6e-09 35.9 0.2 7.9 4 1 4 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KXG50233.1 - 4.8e-26 90.0 4.3 0.001 19.4 0.3 8.2 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.6 KXG50233.1 - 3.3e-25 85.4 2.8 0.00046 20.4 0.1 8.5 9 0 0 9 9 9 6 Ankyrin repeat Pkinase PF00069.25 KXG50234.1 - 4.7e-11 42.5 0.0 2e-09 37.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG50234.1 - 4.8e-05 22.8 0.0 0.001 18.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXG50234.1 - 0.082 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2-Hacid_dh_C PF02826.19 KXG50235.1 - 2.9e-55 186.4 0.0 4.1e-55 185.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXG50235.1 - 1.2e-19 70.4 0.0 1.5e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXG50235.1 - 1.7e-07 31.6 0.3 4.8e-07 30.1 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXG50235.1 - 0.0095 16.5 0.0 0.021 15.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KXG50235.1 - 0.03 13.6 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 KXG50235.1 - 0.11 13.1 0.0 0.77 10.3 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain Aegerolysin PF06355.13 KXG50236.1 - 1.5e-27 96.3 1.9 1.7e-27 96.1 1.9 1.0 1 0 0 1 1 1 1 Aegerolysin Pkinase PF00069.25 KXG50237.1 - 1.6e-67 227.6 0.0 2e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG50237.1 - 9.2e-30 103.8 0.0 1.3e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXG50237.1 - 0.00047 20.1 0.3 0.0019 18.2 0.1 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXG50237.1 - 0.00086 18.3 0.3 0.052 12.5 0.1 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 KXG50237.1 - 0.0012 18.3 0.1 0.003 16.9 0.1 1.8 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KXG50237.1 - 0.026 13.6 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FA_desaturase PF00487.24 KXG50238.1 - 1.2e-13 51.5 20.5 2.4e-13 50.5 20.5 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXG50238.1 - 3.3e-11 43.2 0.0 5.8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CFEM PF05730.11 KXG50239.1 - 1.1e-14 54.3 6.8 1.6e-14 53.7 6.8 1.3 1 0 0 1 1 1 1 CFEM domain Acyl_transf_3 PF01757.22 KXG50241.1 - 1.9e-41 142.2 33.0 2.4e-41 142.0 33.0 1.1 1 0 0 1 1 1 1 Acyltransferase family Gly_transf_sug PF04488.15 KXG50242.1 - 1.7e-14 54.2 0.0 3.4e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Ank_2 PF12796.7 KXG50243.1 - 1.4e-63 211.5 0.0 1.8e-16 60.5 0.0 4.5 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG50243.1 - 3.1e-45 152.0 0.1 1.8e-11 44.3 0.0 7.1 3 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG50243.1 - 1.7e-40 132.4 0.1 0.0025 18.2 0.0 10.1 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 KXG50243.1 - 1.3e-36 124.1 2.8 5.3e-09 36.2 0.0 8.2 3 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KXG50243.1 - 3.2e-35 119.0 2.2 0.00065 20.0 0.0 9.4 9 1 0 9 9 9 7 Ankyrin repeat Methyltransf_2 PF00891.18 KXG50244.1 - 4.1e-17 62.2 0.0 8.6e-16 57.9 0.0 2.4 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KXG50244.1 - 3.4e-07 30.9 0.0 1.9e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXG50244.1 - 7.1e-05 22.4 0.0 0.0002 20.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KXG50244.1 - 7.4e-05 22.6 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG50244.1 - 0.00026 21.7 0.0 0.0016 19.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG50244.1 - 0.009 15.9 0.0 0.028 14.3 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG50244.1 - 0.012 15.0 0.0 0.047 13.0 0.0 1.8 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KXG50244.1 - 0.014 16.1 0.0 0.05 14.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 KXG50244.1 - 0.021 14.3 0.0 0.059 12.8 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.9 KXG50244.1 - 0.033 13.9 0.0 0.09 12.5 0.0 1.7 2 0 0 2 2 2 0 Lysine methyltransferase DREV PF05219.12 KXG50244.1 - 0.1 11.7 0.0 0.34 10.0 0.0 1.8 2 0 0 2 2 2 0 DREV methyltransferase TUSC2 PF15000.6 KXG50244.1 - 0.11 12.8 0.2 0.22 11.8 0.2 1.5 1 0 0 1 1 1 0 Tumour suppressor candidate 2 Methyltransf_18 PF12847.7 KXG50244.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXG50244.1 - 0.19 11.5 0.4 17 5.0 0.0 2.4 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) p450 PF00067.22 KXG50245.1 - 1.9e-56 191.7 0.0 2.5e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RICTOR_N PF14664.6 KXG50245.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term ketoacyl-synt PF00109.26 KXG50246.1 - 3.6e-74 249.6 0.0 1.2e-73 247.8 0.0 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXG50246.1 - 6.7e-33 113.2 1.3 1.4e-32 112.2 1.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 KXG50246.1 - 3.2e-27 94.2 0.1 1.8e-26 91.8 0.0 2.4 3 0 0 3 3 2 1 Helix-turn-helix domain PS-DH PF14765.6 KXG50246.1 - 5.7e-15 55.3 0.0 8.6e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 KXG50246.1 - 8.3e-14 52.1 0.0 2.1e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KXG50246.1 - 9.5e-13 48.3 0.9 2.4e-12 47.0 0.9 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 KXG50246.1 - 4e-11 43.0 0.0 1.2e-09 38.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Abhydrolase_3 PF07859.13 KXG50246.1 - 1.5e-10 41.3 0.0 9.8e-10 38.6 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_25 PF13649.6 KXG50246.1 - 3.6e-09 37.2 0.0 1.1e-08 35.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 KXG50246.1 - 8.3e-09 35.5 0.8 7.6e-08 32.4 0.0 2.8 3 0 0 3 3 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KXG50246.1 - 1.3e-07 31.4 0.0 0.011 15.3 0.0 3.0 3 0 0 3 3 3 2 Acyl transferase domain Zn_clus PF00172.18 KXG50246.1 - 1.8e-07 31.1 13.2 3.7e-07 30.2 13.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_31 PF13847.6 KXG50246.1 - 5.6e-07 29.5 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.21 KXG50246.1 - 1.2e-06 28.2 0.0 0.0052 16.3 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Methyltransf_11 PF08241.12 KXG50246.1 - 1.1e-05 26.0 0.0 3e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXG50246.1 - 1.4e-05 25.5 0.0 6.8e-05 23.3 0.0 2.2 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KXG50246.1 - 3.8e-05 23.2 0.1 7.1e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Fungal_trans PF04082.18 KXG50246.1 - 0.00026 20.1 0.0 0.00059 19.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.7 KXG50246.1 - 0.00056 20.6 0.7 0.002 18.8 0.7 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KXG50246.1 - 0.0013 18.3 0.0 2.8 7.5 0.0 3.5 3 0 0 3 3 3 1 Dienelactone hydrolase family Ubie_methyltran PF01209.18 KXG50246.1 - 0.0028 17.1 0.0 0.0063 15.9 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 KXG50246.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_33 PF10017.9 KXG50246.1 - 0.018 14.2 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Thioesterase PF00975.20 KXG50246.1 - 0.021 15.0 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.16 KXG50246.1 - 0.026 14.3 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase ACP_syn_III PF08545.10 KXG50246.1 - 0.034 14.0 1.1 0.19 11.6 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Hydrolase_4 PF12146.8 KXG50246.1 - 0.047 12.9 0.0 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 RrnaAD PF00398.20 KXG50246.1 - 0.05 12.7 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MFS_1 PF07690.16 KXG50247.1 - 7.7e-35 120.4 42.9 1.2e-34 119.8 42.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Adeno_E4_34 PF04528.13 KXG50247.1 - 0.58 10.0 5.0 0.081 12.8 0.4 1.7 2 0 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region NmrA PF05368.13 KXG50248.1 - 1e-12 48.1 0.0 1.1e-09 38.2 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KXG50248.1 - 2.8e-07 30.6 0.0 6.7e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Collagen PF01391.18 KXG50249.1 - 3e-05 23.7 13.5 5.9e-05 22.7 13.5 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Dynactin_p62 PF05502.13 KXG50250.1 - 0.13 11.0 0.5 0.17 10.6 0.5 1.0 1 0 0 1 1 1 0 Dynactin p62 family Collagen PF01391.18 KXG50251.1 - 5.5e-21 74.1 103.4 1.2e-08 34.6 32.2 3.9 2 1 2 4 4 4 3 Collagen triple helix repeat (20 copies) RuvA_N PF01330.21 KXG50251.1 - 0.01 15.9 0.1 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 RuvA N terminal domain PAN_1 PF00024.26 KXG50251.1 - 0.89 9.6 6.5 0.15 12.0 2.4 1.8 2 0 0 2 2 2 0 PAN domain Gly_transf_sug PF04488.15 KXG50254.1 - 1e-11 45.3 0.2 1.7e-11 44.6 0.2 1.5 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KXG50254.1 - 0.011 15.0 0.0 0.032 13.5 0.0 1.7 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DAO PF01266.24 KXG50255.1 - 4.5e-30 105.4 0.1 6.4e-30 104.9 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXG50255.1 - 2.1e-06 27.8 0.1 0.02 14.9 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 KXG50255.1 - 0.00012 21.3 0.1 0.00043 19.5 0.0 1.9 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KXG50255.1 - 0.00079 18.7 0.0 0.017 14.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXG50255.1 - 0.0022 17.1 0.2 0.16 11.0 0.0 2.4 2 1 1 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXG50255.1 - 0.0052 17.0 0.0 0.016 15.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 KXG50255.1 - 0.018 15.3 0.0 5.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_3 PF13738.6 KXG50255.1 - 0.039 13.2 0.0 7.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase S1-P1_nuclease PF02265.16 KXG50256.1 - 3.5e-69 233.4 0.4 4.1e-69 233.2 0.4 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease GST_C PF00043.25 KXG50258.1 - 1.7e-13 50.6 0.0 2.8e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXG50258.1 - 2.1e-13 50.5 0.0 4.1e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXG50258.1 - 8.1e-12 45.3 0.0 1.7e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXG50258.1 - 8.6e-12 45.1 0.0 1.4e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXG50258.1 - 1.8e-11 44.1 0.1 4e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXG50258.1 - 9.3e-09 35.2 0.1 1.7e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXG50258.1 - 0.034 14.7 0.1 0.28 11.8 0.1 2.1 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain SR-25 PF10500.9 KXG50259.1 - 0.45 10.1 8.8 0.52 9.9 8.8 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 KXG50259.1 - 0.76 10.1 7.8 0.88 9.9 7.8 1.2 1 0 0 1 1 1 0 Early growth response N-terminal domain SSP160 PF06933.11 KXG50259.1 - 9.4 4.3 10.9 11 4.1 10.9 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AAA PF00004.29 KXG50260.1 - 2.4e-11 44.2 0.0 6.6e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXG50260.1 - 2.4e-06 27.9 0.0 5.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXG50260.1 - 4.9e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXG50260.1 - 8.3e-05 22.4 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KXG50260.1 - 0.0019 18.2 0.0 0.0063 16.5 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KXG50260.1 - 0.002 18.5 0.2 0.027 14.8 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KXG50260.1 - 0.0028 17.8 0.0 0.0071 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KXG50260.1 - 0.0076 16.2 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_14 PF13173.6 KXG50260.1 - 0.048 13.7 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXG50260.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KXG50260.1 - 0.12 12.0 0.0 0.87 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXG50260.1 - 0.13 12.8 0.0 0.41 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXG50260.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ETF PF01012.21 KXG50261.1 - 7.1e-45 153.1 2.2 7.1e-45 153.1 2.2 1.7 2 1 1 3 3 3 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KXG50261.1 - 8.4e-33 112.3 0.2 1.7e-32 111.2 0.2 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Ribosomal_L1 PF00687.21 KXG50262.1 - 1.4e-61 207.8 2.7 2.3e-61 207.1 2.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SUN PF03856.13 KXG50263.1 - 2.4e-92 308.8 6.6 3.2e-92 308.4 6.6 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) MIF4G PF02854.19 KXG50265.1 - 4.9e-60 202.8 0.0 2.4e-34 118.9 0.0 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 KXG50265.1 - 8.8e-41 139.8 9.5 8.8e-41 139.8 9.5 2.9 3 0 0 3 3 3 1 Up-frameshift suppressor 2 TRI12 PF06609.13 KXG50266.1 - 2e-47 161.9 27.7 2.7e-47 161.5 27.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXG50266.1 - 2.5e-14 53.0 51.2 2.5e-14 53.0 51.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG50266.1 - 6.1e-09 35.2 11.2 6.1e-09 35.2 11.2 3.4 4 1 0 4 4 4 1 Sugar (and other) transporter adh_short PF00106.25 KXG50267.1 - 1.6e-41 141.9 0.0 2.1e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG50267.1 - 1.6e-29 103.2 0.0 2.1e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG50267.1 - 1.4e-05 25.1 0.1 2.8e-05 24.1 0.0 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXG50267.1 - 0.0022 17.5 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXG50267.1 - 0.053 13.4 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXG50267.1 - 0.19 12.0 0.0 1 9.6 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KXG50268.1 - 6.1e-34 117.2 0.0 8.6e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG50268.1 - 2.5e-25 89.4 0.0 3.8e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG50268.1 - 0.003 17.5 0.4 0.069 13.1 0.1 2.5 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 KXG50268.1 - 0.029 13.8 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_12 PF08242.12 KXG50268.1 - 0.099 13.4 0.0 0.18 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ABC_tran_CTD PF16326.5 KXG50269.1 - 0.065 13.5 1.0 0.61 10.4 0.0 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain CHCH PF06747.13 KXG50270.1 - 5.1e-08 32.9 4.5 8.6e-08 32.1 4.5 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KXG50270.1 - 0.0022 18.4 1.8 0.0043 17.4 1.8 1.5 1 0 0 1 1 1 1 GCK domain SecD-TM1 PF13721.6 KXG50270.1 - 0.15 12.5 0.0 1.2 9.6 0.0 2.0 2 0 0 2 2 2 0 SecD export protein N-terminal TM region Pneumo_att_G PF05539.11 KXG50270.1 - 4.3 6.8 6.1 7.2 6.1 6.1 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G TPK_catalytic PF04263.16 KXG50271.1 - 1.1e-31 109.4 0.0 2.6e-31 108.1 0.0 1.6 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KXG50271.1 - 1.2e-20 72.9 0.0 2.1e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain YqzE PF14038.6 KXG50271.1 - 0.13 12.2 0.1 1.1 9.3 0.1 2.1 2 0 0 2 2 2 0 YqzE-like protein Rho_N PF07498.12 KXG50272.1 - 0.032 14.1 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Mito_carr PF00153.27 KXG50273.1 - 6e-61 202.4 1.4 4.6e-19 68.1 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein UPF0121 PF03661.13 KXG50273.1 - 2.4e-31 109.0 8.0 3.8e-31 108.3 8.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) SH3_3 PF08239.11 KXG50274.1 - 0.0028 17.9 0.1 0.0052 17.0 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 KXG50274.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Zn_clus PF00172.18 KXG50276.1 - 1.7e-07 31.2 12.4 3.2e-07 30.4 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXG50276.1 - 3.2e-06 26.2 0.0 0.056 12.2 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Rax2 PF12768.7 KXG50277.1 - 3.8e-73 245.5 0.4 1.9e-69 233.4 0.0 3.2 2 1 0 2 2 2 2 Cortical protein marker for cell polarity Kelch_6 PF13964.6 KXG50277.1 - 0.091 13.1 1.4 10 6.6 0.0 4.6 6 0 0 6 6 6 0 Kelch motif POB3_N PF17292.2 KXG50278.1 - 3e-31 107.7 0.1 1.4e-29 102.3 0.0 2.9 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 KXG50278.1 - 8.1e-29 99.3 1.9 2.6e-28 97.7 0.0 2.9 5 0 0 5 5 5 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KXG50278.1 - 3.8e-27 94.5 0.1 5.9e-26 90.7 0.0 2.7 3 0 0 3 3 3 1 Histone chaperone Rttp106-like PH_TFIIH PF08567.11 KXG50278.1 - 0.022 15.1 0.0 0.86 10.0 0.0 3.1 4 0 0 4 4 4 0 TFIIH p62 subunit, N-terminal domain Septin PF00735.18 KXG50279.1 - 2.1e-121 404.5 0.2 2.1e-121 404.5 0.2 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KXG50279.1 - 1.4e-07 31.6 0.7 2.6e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXG50279.1 - 1e-06 28.5 1.4 0.0002 20.9 0.0 2.8 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXG50279.1 - 6.8e-06 26.1 1.4 0.00036 20.5 0.3 2.9 2 1 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KXG50279.1 - 0.0002 20.8 1.4 0.00047 19.5 0.0 2.1 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.27 KXG50279.1 - 0.00025 21.6 4.1 0.027 15.0 0.0 3.1 2 1 0 2 2 2 1 ABC transporter Roc PF08477.13 KXG50279.1 - 0.00056 20.1 0.0 0.0016 18.6 0.0 1.8 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KXG50279.1 - 0.0019 18.6 0.1 0.0057 17.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.22 KXG50279.1 - 0.0021 17.7 0.3 0.019 14.5 0.0 2.6 3 0 0 3 3 2 1 Ras family AAA_22 PF13401.6 KXG50279.1 - 0.0034 17.7 1.2 0.011 16.0 0.0 2.4 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXG50279.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KXG50279.1 - 0.03 14.1 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KXG50279.1 - 0.055 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activat PF00158.26 KXG50279.1 - 0.088 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 KXG50279.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TSNAXIP1_N PF15739.5 KXG50279.1 - 0.092 13.1 9.5 5.7 7.4 0.0 2.9 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus RNA_helicase PF00910.22 KXG50279.1 - 0.12 12.7 0.4 0.67 10.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 KXG50279.1 - 0.27 11.0 5.1 2.7 7.7 0.1 3.2 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.15 KXG50279.1 - 0.28 10.7 4.8 0.51 9.9 4.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 KXG50279.1 - 0.39 9.7 5.6 0.58 9.2 5.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF87 PF01935.17 KXG50279.1 - 0.51 10.4 3.3 3.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 KXG50279.1 - 0.72 9.9 8.1 0.2 11.7 0.3 3.4 2 2 0 3 3 3 0 Dynamin family AAA_23 PF13476.6 KXG50279.1 - 1.1 9.7 0.0 1.1 9.7 0.0 2.2 2 1 0 2 2 1 0 AAA domain Strep_SA_rep PF06696.11 KXG50279.1 - 4.6 7.4 6.4 2.2 8.4 3.4 2.0 1 1 1 2 2 2 0 Streptococcal surface antigen repeat DUF3987 PF13148.6 KXG50279.1 - 5.2 6.0 9.1 1.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Pkinase PF00069.25 KXG50280.1 - 2.7e-30 105.6 0.0 3.3e-29 102.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG50280.1 - 6.4e-13 48.6 0.0 2.9e-08 33.3 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase RRM_1 PF00076.22 KXG50281.1 - 2.5e-26 91.3 0.2 8.8e-12 44.7 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OGG_N PF07934.12 KXG50282.1 - 2.8e-25 88.7 1.1 5.9e-25 87.7 1.1 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KXG50282.1 - 1.5e-14 54.3 0.0 3.6e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ribosomal_S13_N PF08069.12 KXG50283.1 - 3e-29 100.8 0.1 4.7e-29 100.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KXG50283.1 - 1.1e-14 54.4 0.1 1.4e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KXG50283.1 - 0.015 15.2 0.1 0.037 14.0 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain VRR_NUC PF08774.11 KXG50284.1 - 3.1e-24 85.1 0.1 1.1e-23 83.3 0.0 2.0 2 0 0 2 2 2 1 VRR-NUC domain Dpy-30 PF05186.13 KXG50285.1 - 2.6e-15 55.8 0.1 3.3e-15 55.5 0.1 1.1 1 0 0 1 1 1 1 Dpy-30 motif RRM_1 PF00076.22 KXG50286.1 - 1.9e-20 72.4 0.0 3.1e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXG50286.1 - 0.00073 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EPL1 PF10513.9 KXG50287.1 - 1.4e-31 110.0 0.0 5.2e-31 108.2 0.0 2.0 1 1 0 1 1 1 1 Enhancer of polycomb-like zf-HC5HC2H_2 PF13832.6 KXG50287.1 - 1.3e-30 105.8 5.0 1.3e-30 105.8 5.0 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KXG50287.1 - 4.2e-26 91.0 1.7 4.2e-26 91.0 1.7 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KXG50287.1 - 5e-15 54.8 8.4 7.8e-14 50.9 2.3 2.6 2 0 0 2 2 2 2 PHD-finger PHD PF00628.29 KXG50287.1 - 3.4e-10 39.7 20.0 7.5e-09 35.3 9.5 2.6 2 0 0 2 2 2 2 PHD-finger Bromodomain PF00439.25 KXG50287.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Bromodomain zf-PHD-like PF15446.6 KXG50287.1 - 2.3 7.8 11.1 0.019 14.6 1.8 2.1 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING-like PF08746.11 KXG50287.1 - 3.8 7.9 19.8 0.031 14.6 4.6 2.6 2 0 0 2 2 2 0 RING-like domain Prok-RING_1 PF14446.6 KXG50287.1 - 9.7 6.2 15.8 0.83 9.6 7.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Peptidase_M22 PF00814.25 KXG50289.1 - 2.9e-44 151.8 0.0 2.3e-43 148.9 0.0 2.1 1 1 0 1 1 1 1 Glycoprotease family FGGY_C PF02782.16 KXG50289.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Mito_carr PF00153.27 KXG50291.1 - 1.9e-73 242.5 0.1 1.8e-25 88.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KXG50291.1 - 9.9e-12 45.1 4.6 1.5e-06 28.5 0.7 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 KXG50291.1 - 3.7e-11 42.0 6.6 1.8e-06 27.4 0.2 5.2 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 KXG50291.1 - 2.6e-08 32.8 11.9 5.7e-06 25.5 0.2 5.1 7 0 0 7 7 7 2 EF hand EF-hand_8 PF13833.6 KXG50291.1 - 1.8e-07 30.9 0.6 1.5 8.8 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KXG50291.1 - 2e-05 23.9 4.5 8.9e-05 21.8 0.3 3.3 3 0 0 3 3 3 1 EF hand DUF5321 PF17254.2 KXG50292.1 - 5.8e-57 191.6 5.5 7.2e-57 191.3 5.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) Moulting_cycle PF04870.16 KXG50292.1 - 0.095 12.0 7.8 0.13 11.5 7.8 1.2 1 0 0 1 1 1 0 Moulting cycle Presenilin PF01080.17 KXG50292.1 - 0.32 9.7 1.5 0.33 9.7 1.5 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_C50 PF03568.17 KXG50293.1 - 3.2e-156 520.4 0.0 2.8e-155 517.3 0.0 2.4 2 0 0 2 2 2 1 Peptidase family C50 CHAT PF12770.7 KXG50293.1 - 4.4e-05 23.0 0.9 0.0065 15.9 0.0 3.4 2 1 0 3 3 3 1 CHAT domain TPR_12 PF13424.6 KXG50293.1 - 0.0014 18.9 20.3 1.4 9.2 0.6 6.1 4 2 1 5 5 5 3 Tetratricopeptide repeat RPN7 PF10602.9 KXG50293.1 - 0.013 15.2 4.3 8.6 6.0 0.1 3.9 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_2 PF07719.17 KXG50293.1 - 0.016 15.3 13.0 3.8 7.9 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXG50293.1 - 0.28 11.1 3.8 37 4.4 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXG50293.1 - 0.61 11.1 17.5 5.6 8.1 0.2 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXG50293.1 - 0.83 10.0 6.5 11 6.5 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXG50293.1 - 1.6 9.4 12.3 34 5.2 0.2 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Esterase PF00756.20 KXG50294.1 - 6.1e-53 180.0 0.0 7.7e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KXG50294.1 - 2.9e-07 30.2 0.0 5.9e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXG50294.1 - 0.00031 20.3 0.0 0.00057 19.4 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXG50294.1 - 0.00091 18.6 0.1 0.0016 17.8 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KXG50294.1 - 0.0017 17.3 0.0 0.0037 16.2 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.12 KXG50294.1 - 0.0029 16.3 0.0 0.0041 15.8 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.25 KXG50294.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.20 KXG50294.1 - 0.02 14.6 0.7 0.037 13.7 0.7 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KXG50294.1 - 0.045 13.6 0.0 0.1 12.5 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KXG50294.1 - 0.056 12.4 0.0 0.35 9.8 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase Abhydrolase_6 PF12697.7 KXG50294.1 - 0.091 13.3 0.0 0.12 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXG50294.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KXG50294.1 - 0.2 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Xpo1 PF08389.12 KXG50295.1 - 3.1e-40 137.6 3.0 4.3e-40 137.2 0.0 2.9 4 0 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.22 KXG50295.1 - 0.0092 16.2 0.2 13 6.4 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat FGGY_C PF02782.16 KXG50296.1 - 4.7e-33 114.6 0.0 7.7e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXG50296.1 - 1.2e-22 80.7 0.0 2.5e-13 50.2 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain RHS_repeat PF05593.14 KXG50296.1 - 0.096 13.2 0.3 0.21 12.2 0.3 1.5 1 0 0 1 1 1 0 RHS Repeat Cation_efflux PF01545.21 KXG50297.1 - 1.3e-62 211.1 4.6 1.6e-62 210.8 4.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXG50297.1 - 6.6e-05 23.0 0.4 0.00018 21.6 0.4 1.8 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Pkinase PF00069.25 KXG50298.1 - 1.8e-73 247.2 0.0 2.4e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG50298.1 - 8.5e-35 120.3 0.0 1.3e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SIR2 PF02146.17 KXG50298.1 - 2.1e-31 109.2 0.0 3.6e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 Sir2 family Haspin_kinase PF12330.8 KXG50298.1 - 0.00074 18.6 0.0 0.0053 15.8 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXG50298.1 - 0.027 13.8 0.1 0.067 12.5 0.1 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXG50298.1 - 0.031 13.6 0.3 0.15 11.4 0.0 2.1 2 1 0 2 2 2 0 Kinase-like APH PF01636.23 KXG50298.1 - 0.068 13.1 0.3 0.21 11.5 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KXG50298.1 - 0.14 11.2 0.1 0.38 9.8 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 Dicty_CAR PF05462.11 KXG50299.1 - 2.5e-08 33.4 9.9 4.4e-08 32.6 9.9 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.8 KXG50299.1 - 1.1e-07 31.9 10.2 1.8e-07 31.2 10.2 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KXG50299.1 - 0.0075 15.6 5.9 0.0093 15.3 5.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TMEMspv1-c74-12 PF11044.8 KXG50299.1 - 0.19 11.8 0.3 0.19 11.8 0.3 1.9 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Nnf1 PF03980.14 KXG50300.1 - 1e-33 116.0 5.4 1.7e-33 115.3 5.4 1.4 1 0 0 1 1 1 1 Nnf1 BAG6 PF12057.8 KXG50300.1 - 0.002 17.8 0.4 0.0033 17.1 0.4 1.4 1 0 0 1 1 1 1 BCL2-associated athanogene 6 Apolipoprotein PF01442.18 KXG50300.1 - 0.042 13.7 10.4 0.21 11.5 8.0 2.1 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain TPR_11 PF13414.6 KXG50301.1 - 0.23 11.2 5.4 5.3 6.8 0.0 4.4 6 0 0 6 6 6 0 TPR repeat NTF2 PF02136.20 KXG50303.1 - 5.1e-27 94.8 0.2 8e-27 94.2 0.2 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KXG50303.1 - 1.3e-07 31.3 0.0 2.8e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP90 PF00183.18 KXG50304.1 - 5.5e-220 731.6 27.8 7e-220 731.3 27.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KXG50304.1 - 8.8e-15 55.2 0.1 1.7e-14 54.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXG50304.1 - 5.5e-09 36.0 0.1 5.5e-09 36.0 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 KXG50304.1 - 0.082 12.9 0.2 0.23 11.5 0.2 1.7 1 0 0 1 1 1 0 Tumour suppressor protein Bromodomain PF00439.25 KXG50305.1 - 1e-20 73.6 0.1 1.8e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_10 PF13673.7 KXG50305.1 - 2e-06 27.8 0.1 3.5e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG50305.1 - 2.1e-06 28.0 0.0 4.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXG50305.1 - 0.0023 18.3 0.2 0.0047 17.3 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank_2 PF12796.7 KXG50307.1 - 3.8e-39 133.1 4.9 3e-14 53.4 0.2 4.2 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG50307.1 - 2.5e-35 120.4 4.7 3.1e-08 34.0 0.1 6.5 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG50307.1 - 1e-33 111.5 3.1 1.2e-05 25.3 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 KXG50307.1 - 3.9e-31 106.1 12.9 4.2e-06 27.0 0.0 8.5 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 KXG50307.1 - 7.9e-24 83.4 6.6 3.2e-08 33.7 0.1 6.1 3 3 4 7 7 7 5 Ankyrin repeats (many copies) F-box-like PF12937.7 KXG50307.1 - 0.0026 17.6 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KXG50307.1 - 0.007 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 F-box F-box PF00646.33 KXG50307.1 - 0.028 14.3 0.1 0.055 13.4 0.1 1.4 1 0 0 1 1 1 0 F-box domain E3_binding PF02817.17 KXG50307.1 - 0.17 12.3 0.9 2.5 8.5 0.0 3.0 2 0 0 2 2 2 0 e3 binding domain DUF2520 PF10728.9 KXG50307.1 - 1.2 8.9 6.1 8.6 6.1 0.2 3.6 1 1 1 3 3 3 0 Domain of unknown function (DUF2520) VWA_3_C PF18571.1 KXG50307.1 - 3.3 7.7 9.0 13 5.8 0.1 4.1 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain But2 PF09792.9 KXG50308.1 - 7.8e-59 198.1 1.4 7.8e-59 198.1 1.4 2.1 2 1 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain Methyltransf_23 PF13489.6 KXG50309.1 - 3.2e-13 49.8 4.8 7.2e-13 48.7 4.8 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG50309.1 - 1.4e-12 47.6 0.0 2e-12 47.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG50309.1 - 1.1e-11 45.2 0.0 2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG50309.1 - 2e-11 44.5 0.0 3.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG50309.1 - 2e-08 34.8 0.0 4e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG50309.1 - 1.4e-05 24.5 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family tRNA_U5-meth_tr PF05958.11 KXG50309.1 - 0.01 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DREV PF05219.12 KXG50309.1 - 0.019 14.0 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase TPMT PF05724.11 KXG50309.1 - 0.03 14.0 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 KXG50309.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.10 KXG50309.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase UDPG_MGDP_dh_N PF03721.14 KXG50309.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Zip PF02535.22 KXG50309.1 - 0.7 9.1 7.2 0.95 8.6 7.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter F-box PF00646.33 KXG50310.1 - 0.015 15.1 0.5 0.038 13.9 0.5 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KXG50310.1 - 0.021 14.7 0.3 0.046 13.6 0.3 1.6 1 0 0 1 1 1 0 F-box-like Glyco_hydro_18 PF00704.28 KXG50311.1 - 1.9e-50 172.4 2.7 2.9e-50 171.8 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KXG50311.1 - 1.1e-05 25.8 6.4 1.1e-05 25.8 6.4 4.1 4 1 0 4 4 4 1 Chitin recognition protein LysM PF01476.20 KXG50311.1 - 0.00025 21.0 0.0 0.0032 17.5 0.1 2.6 3 0 0 3 3 3 1 LysM domain DNase_NucA_NucB PF14040.6 KXG50311.1 - 0.00099 19.5 1.4 0.07 13.5 0.0 2.9 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB Trypsin PF00089.26 KXG50313.1 - 0.017 14.9 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Trypsin Peptidase_S7 PF00949.21 KXG50313.1 - 0.027 14.3 0.1 0.25 11.2 0.1 2.3 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease Ank_2 PF12796.7 KXG50314.1 - 9.3e-27 93.4 2.3 1.3e-16 60.9 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXG50314.1 - 3.5e-21 74.6 6.6 1.8e-06 28.2 0.2 5.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KXG50314.1 - 6.2e-19 68.1 0.7 1.5e-05 25.5 0.0 4.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG50314.1 - 1.5e-17 61.8 0.3 0.00041 20.6 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KXG50314.1 - 3.6e-14 52.6 4.4 0.00026 21.2 0.1 4.5 2 1 3 5 5 5 4 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KXG50314.1 - 0.0016 18.2 4.3 0.9 9.5 0.1 4.3 5 0 0 5 5 5 2 von Willebrand factor type A C-terminal domain AMP-binding PF00501.28 KXG50315.1 - 4.8e-90 302.2 0.0 5.7e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG50315.1 - 3.4e-13 50.4 0.0 6.9e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 KXG50316.1 - 5e-07 29.0 0.2 2.9e-06 26.5 0.2 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KXG50317.1 - 3.2e-54 184.0 0.0 4e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG50317.1 - 3.8e-41 140.7 0.1 4.5e-41 140.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG50317.1 - 1.6e-09 37.9 0.1 5.6e-09 36.2 0.1 1.7 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 KXG50317.1 - 0.051 12.9 0.0 0.35 10.2 0.0 1.9 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KXG50317.1 - 0.11 11.9 0.1 0.17 11.3 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AA_permease_2 PF13520.6 KXG50318.1 - 1e-30 107.0 45.7 1.1e-24 87.1 27.9 2.1 1 1 1 2 2 2 2 Amino acid permease HATPase_c PF02518.26 KXG50318.1 - 1e-20 74.3 0.0 2.4e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXG50318.1 - 1.4e-19 70.3 0.0 8.6e-19 67.8 0.0 2.4 3 1 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 KXG50318.1 - 1.6e-13 50.5 0.3 3.5e-13 49.4 0.3 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AA_permease PF00324.21 KXG50318.1 - 5.1e-08 32.0 23.3 5.1e-08 32.0 23.3 2.1 2 0 0 2 2 2 1 Amino acid permease HATPase_c_3 PF13589.6 KXG50318.1 - 0.045 13.6 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YlaH PF14036.6 KXG50318.1 - 8.3 6.8 7.6 0.69 10.3 2.4 1.9 2 0 0 2 2 2 0 YlaH-like protein Fructosamin_kin PF03881.14 KXG50319.1 - 4.7e-25 88.4 0.0 6.1e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KXG50319.1 - 0.02 14.9 0.0 0.034 14.1 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family EcKinase PF02958.20 KXG50319.1 - 0.13 11.5 0.0 0.56 9.5 0.0 1.9 2 0 0 2 2 2 0 Ecdysteroid kinase ANAPC4_WD40 PF12894.7 KXG50320.1 - 1e-05 25.8 0.1 0.0064 16.8 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PGAP1 PF07819.13 KXG50320.1 - 6e-05 22.9 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KXG50320.1 - 0.0011 18.5 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NACHT PF05729.12 KXG50320.1 - 0.0013 18.7 0.1 0.0027 17.6 0.1 1.6 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.7 KXG50320.1 - 0.0037 17.9 0.0 0.0099 16.5 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family ATPase PF06745.13 KXG50320.1 - 0.006 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 KaiC Hydrolase_4 PF12146.8 KXG50320.1 - 0.018 14.3 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 HPS3_N PF14761.6 KXG50320.1 - 0.065 12.8 0.3 0.8 9.2 0.0 2.7 3 0 0 3 3 3 0 Hermansky-Pudlak syndrome 3 LCAT PF02450.15 KXG50320.1 - 0.081 12.1 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Rota_NS6 PF04866.12 KXG50320.1 - 0.12 12.6 0.7 0.41 10.9 0.2 2.3 2 0 0 2 2 2 0 Rotavirus non-structural protein 6 MFS_1 PF07690.16 KXG50321.1 - 2.7e-28 98.9 15.5 3.5e-28 98.6 15.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG50321.1 - 7.2e-08 31.7 7.0 9.6e-08 31.3 7.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KXG50321.1 - 0.018 13.9 6.3 0.052 12.4 6.3 1.7 1 1 0 1 1 1 0 MFS_1 like family OATP PF03137.20 KXG50321.1 - 1.8 6.8 7.2 0.34 9.1 0.5 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family adh_short PF00106.25 KXG50322.1 - 2.7e-26 92.2 0.0 2.3e-19 69.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXG50322.1 - 1.1e-14 54.5 0.0 2.8e-08 33.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG50322.1 - 1.4e-08 34.9 0.2 2e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXG50322.1 - 0.0046 16.1 0.0 0.0079 15.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXG50322.1 - 0.0074 15.8 0.1 0.019 14.4 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TPP_enzyme_C PF02775.21 KXG50322.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ABC_tran PF00005.27 KXG50323.1 - 2.7e-43 147.8 0.0 5.8e-27 94.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXG50323.1 - 9.1e-20 71.4 22.8 4.8e-18 65.8 11.4 2.5 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KXG50323.1 - 5.4e-11 42.4 3.3 0.0093 15.4 0.0 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXG50323.1 - 1e-09 38.7 0.2 0.00039 20.3 0.0 3.6 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXG50323.1 - 1e-09 38.8 0.3 0.0012 19.1 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KXG50323.1 - 2.3e-09 38.0 0.2 0.00077 20.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXG50323.1 - 1.4e-08 34.4 0.6 0.0062 16.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXG50323.1 - 9.2e-08 32.2 0.2 0.0039 17.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXG50323.1 - 1.2e-06 29.0 0.0 0.042 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 KXG50323.1 - 1.5e-06 27.9 0.1 0.044 13.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 KXG50323.1 - 1.6e-06 28.6 0.1 0.0099 16.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KXG50323.1 - 1.1e-05 25.4 2.1 0.058 13.3 0.0 3.4 3 0 0 3 3 3 1 NTPase NB-ARC PF00931.22 KXG50323.1 - 1.8e-05 24.1 1.8 0.088 12.0 0.0 3.4 4 0 0 4 4 3 1 NB-ARC domain IstB_IS21 PF01695.17 KXG50323.1 - 1.9e-05 24.5 2.5 0.25 11.0 0.0 3.6 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_33 PF13671.6 KXG50323.1 - 3.1e-05 24.2 0.0 0.48 10.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 KXG50323.1 - 3.4e-05 23.5 0.4 0.098 12.2 0.1 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 KXG50323.1 - 6.6e-05 23.0 0.1 0.21 11.6 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_15 PF13175.6 KXG50323.1 - 7e-05 22.7 0.1 0.21 11.3 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.6 KXG50323.1 - 7.7e-05 23.1 0.5 0.079 13.3 0.0 3.0 3 1 0 3 3 2 1 AAA domain ABC_ATPase PF09818.9 KXG50323.1 - 8.5e-05 21.5 2.3 0.41 9.4 0.0 3.8 4 0 0 4 4 4 1 Predicted ATPase of the ABC class ATPase_2 PF01637.18 KXG50323.1 - 8.7e-05 22.5 0.0 0.45 10.4 0.0 2.4 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea Adeno_IVa2 PF02456.15 KXG50323.1 - 0.00012 21.0 0.3 0.0046 15.8 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein Rad17 PF03215.15 KXG50323.1 - 0.00026 21.0 0.2 0.24 11.3 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 KXG50323.1 - 0.00032 20.7 0.0 1.5 8.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KXG50323.1 - 0.00036 20.4 0.8 1.3 8.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain Roc PF08477.13 KXG50323.1 - 0.00038 20.7 2.3 1.5 9.0 0.0 3.9 5 0 0 5 5 3 2 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 KXG50323.1 - 0.00039 20.8 0.1 0.96 9.9 0.0 2.9 3 0 0 3 3 2 1 RNA helicase MMR_HSR1 PF01926.23 KXG50323.1 - 0.00044 20.3 0.1 0.72 9.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXG50323.1 - 0.00047 20.2 0.0 0.06 13.4 0.0 2.4 2 0 0 2 2 2 1 Dynamin family T2SSE PF00437.20 KXG50323.1 - 0.00061 18.9 0.2 0.12 11.4 0.2 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.6 KXG50323.1 - 0.00063 20.3 0.0 0.54 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 KXG50323.1 - 0.00067 19.4 0.1 0.13 12.0 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 KXG50323.1 - 0.001 18.4 0.1 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 Septin ATP_bind_1 PF03029.17 KXG50323.1 - 0.0011 18.8 0.9 0.5 10.1 0.1 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein TsaE PF02367.17 KXG50323.1 - 0.0013 18.7 0.1 1.5 8.9 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 KXG50323.1 - 0.0016 18.2 0.1 0.14 11.8 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 KXG50323.1 - 0.0021 17.7 0.0 4.3 6.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_35 PF14516.6 KXG50323.1 - 0.0024 16.8 0.3 0.02 13.7 0.1 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_24 PF13479.6 KXG50323.1 - 0.0027 17.4 0.0 0.19 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXG50323.1 - 0.0028 17.6 0.8 2.3 8.1 0.0 2.7 3 0 0 3 3 2 1 NACHT domain AAA_30 PF13604.6 KXG50323.1 - 0.003 17.3 1.0 5.1 6.8 0.0 3.2 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 KXG50323.1 - 0.0042 17.0 0.2 1.1 9.1 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 KXG50323.1 - 0.0061 15.9 0.1 0.76 9.0 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.26 KXG50323.1 - 0.0075 16.0 0.0 2.8 7.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain ATP-synt_ab PF00006.25 KXG50323.1 - 0.0086 15.8 0.2 5 6.7 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 KXG50323.1 - 0.0086 15.3 0.1 1.4 8.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 KXG50323.1 - 0.01 16.1 0.4 5.4 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KXG50323.1 - 0.012 15.4 1.4 2.2 8.0 0.2 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase SbcCD_C PF13558.6 KXG50323.1 - 0.019 15.2 0.0 11 6.3 0.0 3.2 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 KXG50323.1 - 0.019 14.7 0.7 0.17 11.6 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_PrkA PF08298.11 KXG50323.1 - 0.032 13.2 0.1 0.55 9.1 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain GTP_EFTU PF00009.27 KXG50323.1 - 0.032 13.8 0.1 0.8 9.2 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Mg_chelatase PF01078.21 KXG50323.1 - 0.13 11.7 0.2 4.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SRPRB PF09439.10 KXG50323.1 - 0.16 11.4 0.1 19 4.6 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AA_permease PF00324.21 KXG50324.1 - 1.7e-134 449.0 47.7 2.3e-134 448.6 47.7 1.1 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.28 KXG50324.1 - 7.8e-82 275.1 0.0 1.9e-81 273.8 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme AA_permease_2 PF13520.6 KXG50324.1 - 5.3e-31 107.9 53.2 7.4e-31 107.4 53.2 1.1 1 0 0 1 1 1 1 Amino acid permease MARVEL PF01284.23 KXG50325.1 - 2.1e-22 79.7 12.1 2.4e-22 79.5 12.1 1.0 1 0 0 1 1 1 1 Membrane-associating domain RNA_pol_Rpc82 PF05645.13 KXG50326.1 - 4.5e-26 92.1 0.0 3.1e-21 76.3 0.0 2.5 2 1 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KXG50326.1 - 1.7e-18 66.5 1.9 7.8e-10 38.7 0.1 3.7 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KXG50326.1 - 0.00019 21.2 0.1 0.0093 15.8 0.0 2.7 2 1 0 2 2 2 1 TFIIE alpha subunit Peptidase_M16 PF00675.20 KXG50327.1 - 5e-19 68.7 0.1 1.1e-18 67.7 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXG50327.1 - 6e-14 52.5 0.0 1.4e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 KXG50327.1 - 0.0051 16.0 0.0 0.0096 15.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated DUF530 PF04409.12 KXG50327.1 - 0.086 11.2 0.1 0.14 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF530) Bac_DNA_binding PF00216.21 KXG50327.1 - 0.74 10.1 4.5 12 6.2 0.2 2.7 3 0 0 3 3 3 0 Bacterial DNA-binding protein Septin PF00735.18 KXG50328.1 - 1.4e-12 47.5 0.0 7.8e-12 45.1 0.0 1.9 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KXG50328.1 - 0.00011 22.3 0.0 0.00031 20.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KXG50328.1 - 0.0018 17.6 0.0 0.0037 16.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 KXG50328.1 - 0.0028 17.8 0.0 0.0071 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXG50328.1 - 0.0049 17.3 0.0 0.0098 16.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KXG50328.1 - 0.0055 17.0 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXG50328.1 - 0.0097 15.7 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 KXG50328.1 - 0.02 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 KXG50328.1 - 0.022 14.3 0.1 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GAPES3 PF17154.4 KXG50328.1 - 0.023 14.7 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain NACHT PF05729.12 KXG50328.1 - 0.07 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KXG50328.1 - 0.07 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 KXG50328.1 - 0.081 13.1 0.3 0.45 10.7 0.0 2.3 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KXG50328.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KXG50328.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KXG50328.1 - 0.1 13.1 0.0 0.28 11.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KXG50328.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KXG50328.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 KXG50328.1 - 0.22 10.7 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain HLH PF00010.26 KXG50329.1 - 1.1e-11 44.5 3.1 2e-11 43.7 3.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain P19Arf_N PF07392.12 KXG50329.1 - 0.14 12.6 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus FIVAR PF07554.13 KXG50329.1 - 2.4 9.0 9.7 9.7 7.0 9.7 2.1 1 0 0 1 1 1 0 FIVAR domain Sugar_tr PF00083.24 KXG50330.1 - 3.4e-79 266.8 18.5 4e-79 266.6 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG50330.1 - 1.6e-22 79.9 35.7 1e-13 51.0 14.4 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG50330.1 - 0.16 10.8 11.2 0.022 13.7 2.5 2.6 2 1 1 3 3 3 0 MFS_1 like family EF1G PF00647.19 KXG50331.1 - 4.7e-42 142.4 0.6 1e-41 141.3 0.6 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KXG50331.1 - 1.2e-14 54.3 0.1 2.6e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXG50331.1 - 6e-11 42.2 0.1 3.6e-10 39.7 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXG50331.1 - 6e-11 42.5 0.0 2.2e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXG50331.1 - 2.4e-05 24.4 0.0 6.9e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXG50331.1 - 5e-05 23.6 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXG50331.1 - 0.053 13.8 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain OAD_gamma PF04277.13 KXG50331.1 - 0.25 12.0 2.8 0.54 10.9 2.3 1.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Ribosomal_S9 PF00380.19 KXG50332.1 - 1e-27 97.1 1.7 2.8e-20 73.0 0.3 2.6 2 1 1 3 3 3 2 Ribosomal protein S9/S16 PDEase_I_N PF08499.12 KXG50332.1 - 0.028 14.2 0.3 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal DUF3391 PF11871.8 KXG50333.1 - 0.057 14.0 0.7 1.7 9.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) EF-hand_1 PF00036.32 KXG50334.1 - 5e-26 88.3 13.0 1.9e-07 30.2 1.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXG50334.1 - 1.3e-20 73.6 12.3 1.2e-12 48.0 1.8 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KXG50334.1 - 7.3e-20 69.2 7.4 5.9e-05 22.7 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXG50334.1 - 1.8e-17 61.9 10.8 8.7e-06 25.0 0.8 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KXG50334.1 - 2.1e-12 46.7 9.2 0.00017 21.4 0.4 4.0 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXG50334.1 - 3e-07 30.8 0.0 0.0021 18.3 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KXG50334.1 - 0.00029 20.7 7.3 0.36 10.8 0.6 3.7 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KXG50334.1 - 0.099 13.0 0.1 1.5 9.2 0.1 2.7 3 0 0 3 3 3 0 EF-hand domain PMBR PF09373.10 KXG50334.1 - 0.17 12.1 0.0 3 8.2 0.0 2.4 2 0 0 2 2 2 0 Pseudomurein-binding repeat EPL1 PF10513.9 KXG50335.1 - 2.3e-23 83.3 0.3 2.3e-23 83.3 0.3 3.0 2 1 0 2 2 2 1 Enhancer of polycomb-like Med3 PF11593.8 KXG50335.1 - 0.4 9.8 12.8 0.72 9.0 12.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SET PF00856.28 KXG50336.1 - 3.6e-22 79.5 0.0 7.7e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KXG50336.1 - 3.6e-10 40.6 1.2 1.2e-09 39.0 0.1 2.2 1 1 1 2 2 2 1 Rubisco LSMT substrate-binding Peptidase_M22 PF00814.25 KXG50337.1 - 2.6e-85 286.4 0.0 3.1e-85 286.2 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KXG50337.1 - 0.016 14.9 0.0 0.36 10.5 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus AMPK1_CBM PF16561.5 KXG50338.1 - 6.3e-29 100.0 0.0 1.1e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KXG50338.1 - 8.2e-25 86.9 2.9 1e-24 86.6 1.0 2.2 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 KXG50338.1 - 0.078 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Aminotran_1_2 PF00155.21 KXG50339.1 - 1e-38 133.5 0.0 1.5e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KXG50339.1 - 1.7e-06 27.5 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KXG50339.1 - 2.7e-05 23.3 0.0 4.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXG50339.1 - 6.7e-05 21.6 0.0 9.9e-05 21.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXG50339.1 - 0.088 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family TRAP_alpha PF03896.16 KXG50340.1 - 6.7 5.8 10.8 3.9 6.6 6.9 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Mannosyl_trans3 PF11051.8 KXG50341.1 - 8.6e-65 218.8 0.0 1.6e-39 135.9 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative NAD_binding_10 PF13460.6 KXG50342.1 - 2.6e-37 128.5 0.0 2.9e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXG50342.1 - 2.4e-09 37.1 0.1 3.5e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXG50342.1 - 2.9e-07 30.2 0.0 4.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXG50342.1 - 0.0065 15.6 0.1 0.014 14.6 0.1 1.7 2 1 0 2 2 2 1 RmlD substrate binding domain DapB_N PF01113.20 KXG50342.1 - 0.0068 16.5 0.0 0.013 15.7 0.0 1.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 KXG50342.1 - 0.0072 16.6 0.0 0.015 15.6 0.0 1.6 1 1 0 1 1 1 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 KXG50342.1 - 0.0075 15.7 0.0 0.014 14.8 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase T_hemolysin PF12261.8 KXG50342.1 - 0.016 15.0 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Thermostable hemolysin 3Beta_HSD PF01073.19 KXG50342.1 - 0.044 12.8 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family LpxI_N PF17930.1 KXG50342.1 - 1.2 9.1 4.3 5.2 7.0 0.1 2.6 2 1 1 3 3 3 0 LpxI N-terminal domain ABC1 PF03109.16 KXG50343.1 - 1.7e-34 118.5 0.0 4.7e-34 117.1 0.0 1.8 1 0 0 1 1 1 1 ABC1 family UreF PF01730.16 KXG50344.1 - 2.6e-22 79.8 0.1 3.9e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 UreF BRE1 PF08647.11 KXG50345.1 - 1.3e-26 92.5 8.9 1.3e-26 92.5 8.9 8.0 6 3 3 9 9 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KXG50345.1 - 2.3e-09 36.9 6.8 4e-09 36.2 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXG50345.1 - 4.6e-09 36.0 8.3 7.9e-09 35.2 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXG50345.1 - 7.2e-08 32.2 10.2 1.3e-07 31.4 10.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXG50345.1 - 1.3e-07 31.6 5.9 2.5e-07 30.6 5.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXG50345.1 - 2.2e-07 31.1 7.5 3.6e-07 30.4 7.5 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KXG50345.1 - 3.4e-07 30.0 7.6 5.7e-07 29.3 7.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXG50345.1 - 4.9e-06 26.4 10.1 8.1e-06 25.7 10.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DUF1272 PF06906.11 KXG50345.1 - 0.002 18.2 5.3 0.0042 17.1 5.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-rbx1 PF12678.7 KXG50345.1 - 0.004 17.4 5.2 0.012 15.9 4.5 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KXG50345.1 - 0.0067 16.6 6.4 0.012 15.7 6.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KXG50345.1 - 0.035 14.2 5.8 0.092 12.9 5.8 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KXG50345.1 - 0.042 13.7 6.9 0.31 10.9 7.6 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C2H2_jaz PF12171.8 KXG50345.1 - 0.16 12.3 5.9 3.7 7.9 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_17 PF17120.5 KXG50345.1 - 0.19 11.3 3.5 0.35 10.5 3.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 KXG50345.1 - 0.39 10.8 6.9 0.75 9.9 6.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-Nse PF11789.8 KXG50345.1 - 0.45 10.4 4.0 1.2 9.0 4.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ribbon_3 PF13248.6 KXG50345.1 - 0.91 9.0 2.8 2.5 7.6 2.8 1.8 1 1 0 1 1 1 0 zinc-ribbon domain FYVE PF01363.21 KXG50345.1 - 1.1 9.5 11.3 1 9.6 6.2 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-C2HC_2 PF13913.6 KXG50345.1 - 2.3 8.2 6.4 2.3 8.2 2.0 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 KXG50345.1 - 5.1 8.2 9.2 2.7 9.1 0.3 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger Myb_DNA-bind_7 PF15963.5 KXG50346.1 - 1.8e-29 101.4 0.2 1.8e-29 101.4 0.2 2.1 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KXG50346.1 - 4.6e-06 26.7 0.0 9.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4685 PF15737.5 KXG50346.1 - 0.49 10.8 5.5 1 9.8 4.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4685) SARAF PF06682.12 KXG50347.1 - 2.3e-98 329.9 2.3 4.1e-98 329.1 2.3 1.4 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Pkinase PF00069.25 KXG50348.1 - 4e-13 49.3 0.1 8.7e-13 48.2 0.1 1.5 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KXG50348.1 - 6.9e-06 26.2 0.0 1.1e-05 25.6 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXG50348.1 - 8e-06 25.3 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXG50348.1 - 3.2e-05 23.3 0.0 5.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KXG50348.1 - 0.00042 20.0 0.1 0.00067 19.3 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KXG50348.1 - 0.021 14.4 0.1 0.051 13.2 0.0 1.7 2 0 0 2 2 2 0 RIO1 family MMM1 PF10296.9 KXG50349.1 - 1.1e-131 438.9 0.0 1.4e-131 438.5 0.0 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 ATP_transf PF09830.9 KXG50349.1 - 3.3e-13 49.6 0.1 7.4e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase ARD PF03079.14 KXG50350.1 - 6e-47 159.7 0.0 7.3e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KXG50350.1 - 1.3e-10 40.8 0.0 2.1e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KXG50350.1 - 3.8e-06 26.8 0.0 5.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KXG50350.1 - 0.00042 19.9 0.0 0.00058 19.5 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KXG50350.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) GIDA PF01134.22 KXG50351.1 - 7.3e-155 515.9 0.0 8.9e-155 515.6 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KXG50351.1 - 2.6e-66 223.8 0.0 3.5e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 KXG50351.1 - 6.4e-06 25.8 1.0 1e-05 25.1 1.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG50351.1 - 1.5e-05 24.4 0.7 3e-05 23.4 0.4 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG50351.1 - 0.00097 18.3 2.1 0.00097 18.3 2.1 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KXG50351.1 - 0.0053 16.1 0.2 0.014 14.7 0.2 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KXG50351.1 - 0.018 13.8 0.4 0.2 10.3 0.3 2.1 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 KXG50351.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Gti1_Pac2 PF09729.9 KXG50352.1 - 5.2e-63 212.4 0.0 3.1e-62 209.9 0.0 1.9 2 0 0 2 2 2 1 Gti1/Pac2 family CDP-OH_P_transf PF01066.21 KXG50354.1 - 1.5e-14 54.5 0.8 1.5e-14 54.5 0.8 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ABC2_membrane PF01061.24 KXG50355.1 - 5.4e-80 267.7 55.8 7.1e-43 146.5 18.5 3.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KXG50355.1 - 1.7e-39 135.5 0.0 1.2e-20 74.4 0.0 2.9 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXG50355.1 - 9.5e-26 89.5 0.0 9.5e-26 89.5 0.0 3.5 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KXG50355.1 - 1.5e-15 57.6 0.9 6.1e-15 55.6 0.9 2.2 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_18 PF13238.6 KXG50355.1 - 1.4e-06 28.9 0.0 0.00046 20.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXG50355.1 - 1.1e-05 25.4 0.0 0.0079 16.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXG50355.1 - 1.3e-05 25.7 0.0 0.0064 16.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXG50355.1 - 4.1e-05 23.5 0.2 0.00044 20.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KXG50355.1 - 8.4e-05 22.8 0.0 0.0042 17.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KXG50355.1 - 9.4e-05 21.7 13.0 9.4e-05 21.7 13.0 3.2 4 0 0 4 4 3 1 ABC-2 family transporter protein cobW PF02492.19 KXG50355.1 - 0.00029 20.5 0.4 0.0052 16.4 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KXG50355.1 - 0.00064 20.0 3.3 0.0037 17.5 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 KXG50355.1 - 0.00068 19.3 0.1 0.22 11.1 0.1 2.7 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 KXG50355.1 - 0.0012 18.9 0.2 0.11 12.6 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KXG50355.1 - 0.0012 19.1 0.9 0.071 13.4 0.1 3.2 3 1 1 4 4 2 1 AAA domain AAA_29 PF13555.6 KXG50355.1 - 0.0024 17.6 0.1 0.48 10.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KXG50355.1 - 0.0027 17.2 0.3 0.035 13.5 0.0 2.6 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain TsaE PF02367.17 KXG50355.1 - 0.0028 17.6 0.5 0.3 11.1 0.2 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KXG50355.1 - 0.0046 16.9 1.4 0.3 11.0 0.4 2.5 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KXG50355.1 - 0.0057 16.4 0.1 0.24 11.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 KXG50355.1 - 0.0084 16.5 0.1 7.6 7.0 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KXG50355.1 - 0.024 13.8 0.2 3.3 6.8 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.18 KXG50355.1 - 0.14 11.4 0.3 0.5 9.6 0.1 1.9 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.9 KXG50355.1 - 0.28 10.9 0.7 1.8 8.3 0.2 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 KXG50355.1 - 0.57 10.5 2.5 34 4.7 0.2 2.8 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 KXG50355.1 - 9.8 5.8 10.5 3.3 7.4 0.5 2.9 4 0 0 4 4 2 0 AAA domain Tyr-DNA_phospho PF06087.12 KXG50356.1 - 1.2e-83 281.4 0.0 1.6e-83 281.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 KXG50356.1 - 2.6e-05 23.8 4.5 0.0029 17.4 1.2 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif PLDc_2 PF13091.6 KXG50356.1 - 0.00026 20.9 0.0 0.018 14.9 0.0 2.5 2 0 0 2 2 2 1 PLD-like domain HA2 PF04408.23 KXG50358.1 - 6e-28 97.3 0.0 6e-28 97.3 0.0 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXG50358.1 - 6.4e-12 45.8 0.0 2.2e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KXG50358.1 - 4.1e-08 33.5 0.0 9.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KXG50358.1 - 8.5e-08 32.2 0.0 1.1e-06 28.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXG50358.1 - 0.00067 19.9 0.0 0.0028 17.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain BUD22 PF09073.10 KXG50358.1 - 0.001 18.5 32.9 0.001 18.5 32.9 3.2 3 0 0 3 3 3 1 BUD22 AAA_30 PF13604.6 KXG50358.1 - 0.0011 18.8 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXG50358.1 - 0.0011 19.3 0.0 0.0027 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KXG50358.1 - 0.0038 17.2 0.0 2.8 7.9 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KXG50358.1 - 0.0059 15.9 0.7 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KXG50358.1 - 0.034 13.2 0.2 0.091 11.8 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 KXG50358.1 - 0.041 14.4 0.0 0.041 14.4 0.0 4.1 4 1 0 4 4 3 0 AAA domain PhoH PF02562.16 KXG50358.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Complex1_LYR_2 PF13233.6 KXG50358.1 - 1.4 9.7 4.6 2.1 9.1 0.2 2.8 2 0 0 2 2 2 0 Complex1_LYR-like cwf21 PF08312.12 KXG50359.1 - 1.6e-15 57.0 24.8 1.6e-15 57.0 24.8 2.5 1 1 1 2 2 2 1 cwf21 domain DUF1690 PF07956.11 KXG50359.1 - 1.1 9.7 11.1 0.21 12.0 7.9 1.4 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) PUF PF00806.19 KXG50360.1 - 1.9e-61 200.4 11.1 8.4e-10 37.8 0.3 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KXG50360.1 - 0.018 15.4 2.6 18 5.7 0.3 4.2 1 1 3 5 5 5 0 CPL (NUC119) domain DUF234 PF03008.14 KXG50360.1 - 0.11 13.0 1.0 0.53 10.8 0.1 2.5 3 0 0 3 3 3 0 Archaea bacterial proteins of unknown function PLN_propep PF16485.5 KXG50360.1 - 0.15 11.8 0.4 0.55 10.0 0.1 2.2 2 0 0 2 2 2 0 Protealysin propeptide LOB PF03195.14 KXG50360.1 - 0.29 11.7 1.8 5.8 7.6 0.2 3.8 3 1 1 4 4 4 0 Lateral organ boundaries (LOB) domain ParD PF09386.10 KXG50360.1 - 2.6 8.5 4.9 89 3.6 0.0 4.5 4 2 2 6 6 6 0 Antitoxin ParD DUF5326 PF17260.2 KXG50361.1 - 0.0091 16.1 0.5 0.014 15.5 0.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5326) DUF4083 PF13314.6 KXG50361.1 - 0.026 14.5 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF3377 PF11857.8 KXG50361.1 - 0.13 12.2 0.1 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF2621 PF11084.8 KXG50361.1 - 0.2 11.7 0.0 0.27 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) ketoacyl-synt PF00109.26 KXG50362.1 - 2.2e-82 276.5 0.0 4.3e-82 275.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXG50362.1 - 1e-65 222.4 0.1 2.5e-65 221.1 0.1 1.6 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KXG50362.1 - 1.1e-57 194.8 0.1 2.2e-57 193.8 0.1 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KXG50362.1 - 1.4e-51 175.5 1.1 3.2e-51 174.4 1.1 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KXG50362.1 - 2.4e-32 111.4 0.0 1.2e-31 109.1 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 KXG50362.1 - 4.3e-22 79.4 0.0 9.7e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain ADH_zinc_N PF00107.26 KXG50362.1 - 3.2e-21 75.7 0.1 1.1e-20 74.0 0.1 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KXG50362.1 - 4.4e-17 62.6 0.0 1e-16 61.4 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KXG50362.1 - 9.1e-16 59.1 0.0 5.4e-15 56.6 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXG50362.1 - 1.3e-11 44.3 0.0 1.4e-10 40.9 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG50362.1 - 1.9e-07 30.9 0.2 1.2e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Abhydrolase_6 PF12697.7 KXG50362.1 - 1.9e-06 28.6 0.2 1.9e-06 28.6 0.2 3.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family PP-binding PF00550.25 KXG50362.1 - 3.7e-06 27.2 0.0 1.1e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KXG50362.1 - 8.1e-06 25.4 0.4 1.6e-05 24.4 0.4 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 KXG50362.1 - 0.00015 21.6 0.1 0.00041 20.2 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KXG50362.1 - 0.009 15.3 1.4 0.021 14.1 1.3 1.7 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GDP_Man_Dehyd PF16363.5 KXG50362.1 - 0.035 13.5 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Hydrolase_4 PF12146.8 KXG50362.1 - 0.045 13.0 0.0 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PS-DH PF14765.6 KXG50363.1 - 2.6e-60 204.2 0.0 4.4e-60 203.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KXG50363.1 - 2.6e-57 193.6 0.1 1.5e-56 191.1 0.0 2.3 2 0 0 2 2 2 1 KR domain ketoacyl-synt PF00109.26 KXG50363.1 - 2.7e-57 194.3 0.0 4.9e-57 193.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXG50363.1 - 1.4e-50 172.6 0.0 2.2e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXG50363.1 - 7.6e-35 119.5 0.1 1.9e-34 118.2 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXG50363.1 - 1.9e-24 86.3 0.0 4.6e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KXG50363.1 - 4.9e-21 75.3 0.0 1.5e-20 73.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KXG50363.1 - 1.4e-14 54.2 0.0 1.4e-13 50.9 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KXG50363.1 - 3.8e-13 50.0 0.0 1.5e-12 48.1 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG50363.1 - 1.2e-11 44.8 0.0 3.1e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KXG50363.1 - 2.6e-11 44.7 0.0 1.2e-10 42.6 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 KXG50363.1 - 5.1e-11 42.6 0.0 1.2e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG50363.1 - 5.1e-10 39.9 0.0 1.5e-09 38.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KXG50363.1 - 3.3e-07 30.6 0.9 1.1e-06 28.9 0.9 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KXG50363.1 - 3.1e-06 27.0 0.0 7.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXG50363.1 - 3.6e-05 23.3 0.0 0.0019 17.7 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase DUF938 PF06080.12 KXG50363.1 - 0.00043 20.1 0.0 0.00099 18.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_16 PF10294.9 KXG50363.1 - 0.00056 19.7 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase 3Beta_HSD PF01073.19 KXG50363.1 - 0.0035 16.4 0.0 0.0071 15.4 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RrnaAD PF00398.20 KXG50363.1 - 0.019 14.0 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.14 KXG50363.1 - 0.034 13.7 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Thiolase_N PF00108.23 KXG50363.1 - 0.054 12.8 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Phosphodiest PF01663.22 KXG50365.1 - 4.6e-15 56.1 0.3 7.4e-15 55.4 0.3 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KXG50365.1 - 5.2e-06 26.0 0.2 1.1e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KXG50365.1 - 5.6e-05 22.7 0.1 9.4e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.12 KXG50365.1 - 0.063 13.4 0.7 13 5.9 0.1 2.3 2 0 0 2 2 2 0 PglZ domain Glyco_hydro_16 PF00722.21 KXG50366.1 - 3.5e-44 150.4 4.7 5.7e-44 149.7 4.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Inhibitor_I67 PF11405.8 KXG50366.1 - 0.096 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Bromelain inhibitor VI Fungal_trans PF04082.18 KXG50367.1 - 1e-05 24.7 0.6 1.8e-05 23.9 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3384 PF11864.8 KXG50368.1 - 5.3e-111 371.9 5.9 5.3e-111 371.9 5.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KXG50368.1 - 1.3e-46 158.5 0.0 2.2e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KXG50368.1 - 6.4e-42 143.9 0.0 3.7e-36 125.0 0.0 3.4 3 0 0 3 3 3 3 Tuberin CTP_synth_N PF06418.14 KXG50369.1 - 4.1e-121 403.3 0.0 5.5e-121 402.9 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KXG50369.1 - 8.8e-55 185.4 0.0 1.5e-54 184.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXG50369.1 - 1e-06 28.7 0.2 8.7e-06 25.6 0.2 2.2 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 KXG50369.1 - 0.081 13.0 0.0 0.1 12.7 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain CAS_CSE1 PF03378.15 KXG50370.1 - 3.1e-196 652.2 1.6 3.9e-196 651.8 0.6 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KXG50370.1 - 7e-158 525.3 2.4 1e-157 524.8 2.4 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KXG50370.1 - 2.9e-15 55.9 0.2 1.5e-14 53.7 0.2 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF1529 PF07485.11 KXG50370.1 - 0.005 16.7 0.0 0.037 13.9 0.0 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1259) Xpo1 PF08389.12 KXG50370.1 - 0.018 15.1 1.4 1 9.4 0.0 3.8 5 0 0 5 5 5 0 Exportin 1-like protein NARG2_C PF10505.9 KXG50370.1 - 0.089 12.3 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus RF-1 PF00472.20 KXG50371.1 - 2.4e-25 88.7 5.0 2.4e-25 88.7 5.0 1.3 1 1 0 1 1 1 1 RF-1 domain DUF5352 PF17303.2 KXG50371.1 - 0.54 10.1 2.7 0.83 9.5 2.6 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5352) SPT_ssu-like PF11779.8 KXG50372.1 - 1.4e-23 82.3 2.7 2.3e-23 81.6 2.7 1.4 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Pet100 PF09803.9 KXG50373.1 - 4.9e-18 65.4 0.1 6.2e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 Pet100 ECH_1 PF00378.20 KXG50374.1 - 1.7e-25 89.8 0.0 2.4e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXG50374.1 - 2.7e-18 66.6 0.0 3.1e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase D123 PF07065.14 KXG50375.1 - 3.1e-110 368.1 0.1 4.1e-110 367.7 0.1 1.2 1 0 0 1 1 1 1 D123 Vps51 PF08700.11 KXG50376.1 - 4.3e-14 52.4 0.0 3.2e-13 49.6 0.0 2.5 3 0 0 3 3 3 1 Vps51/Vps67 UvrD-helicase PF00580.21 KXG50377.1 - 9.7e-13 48.3 0.1 1.1e-08 34.9 0.0 3.0 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KXG50377.1 - 1.1e-07 31.6 0.0 6e-05 22.6 0.0 3.6 3 1 1 4 4 4 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 KXG50377.1 - 2.2e-06 27.4 0.1 0.013 15.3 0.3 2.6 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KXG50377.1 - 5.3e-06 26.8 0.0 3.4e-05 24.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain SNAP PF14938.6 KXG50377.1 - 0.00029 20.3 3.1 0.00095 18.7 3.1 1.8 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Clathrin PF00637.20 KXG50377.1 - 0.00084 19.2 0.4 0.019 14.8 0.1 3.2 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_8 PF13181.6 KXG50377.1 - 0.013 15.7 1.6 3 8.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_12 PF13087.6 KXG50377.1 - 0.032 13.9 0.0 0.66 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXG50377.1 - 0.033 14.6 0.2 4.9 7.5 0.0 3.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 KXG50377.1 - 0.042 14.1 0.5 2.5 8.4 0.1 3.3 3 0 0 3 3 3 0 AAA domain TPR_11 PF13414.6 KXG50377.1 - 0.046 13.4 0.5 1.3 8.8 0.0 3.1 3 0 0 3 3 3 0 TPR repeat TPR_7 PF13176.6 KXG50377.1 - 0.083 13.0 3.4 18 5.7 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC_tran PF00005.27 KXG50377.1 - 0.11 13.0 0.0 0.36 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter TPR_14 PF13428.6 KXG50377.1 - 0.12 13.2 1.0 1.1e+02 4.0 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXG50377.1 - 0.91 9.5 13.5 4.2 7.3 0.1 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXG50377.1 - 4.1 7.7 17.9 4.8 7.5 0.4 5.7 4 1 2 6 6 6 0 Tetratricopeptide repeat DUF1640 PF07798.11 KXG50378.1 - 2.6e-40 138.3 7.1 3.9e-40 137.7 7.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HIP1_clath_bdg PF16515.5 KXG50378.1 - 0.4 11.3 7.3 0.22 12.1 3.8 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LCIB_C_CA PF18599.1 KXG50378.1 - 2.3 7.4 5.0 0.39 10.0 1.1 1.6 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases HEAT_2 PF13646.6 KXG50380.1 - 2.3e-08 34.3 2.5 0.11 13.0 0.0 5.9 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.22 KXG50380.1 - 2.1e-05 24.4 9.2 1.6 9.2 0.0 8.3 9 0 0 9 9 9 2 HEAT repeat Nuc_recep-AF1 PF11825.8 KXG50380.1 - 0.082 13.0 0.1 0.31 11.1 0.1 2.0 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 HEAT_EZ PF13513.6 KXG50380.1 - 0.41 11.2 16.2 2.8 8.5 0.0 7.8 9 0 0 9 9 9 0 HEAT-like repeat Transcrip_reg PF01709.20 KXG50381.1 - 9.2e-70 234.8 0.5 1e-69 234.6 0.5 1.0 1 0 0 1 1 1 1 Transcriptional regulator NapD PF03927.13 KXG50381.1 - 0.044 13.8 1.3 10 6.3 0.0 3.2 2 1 1 3 3 3 0 NapD protein CENP-I PF07778.11 KXG50382.1 - 1.3e-42 146.3 0.3 4.4e-42 144.5 0.3 1.7 1 1 0 1 1 1 1 Mis6 CLPTM1 PF05602.12 KXG50383.1 - 9.3e-161 535.6 0.1 1.1e-160 535.4 0.1 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) adh_short PF00106.25 KXG50384.1 - 2.7e-24 85.7 0.0 5.1e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG50384.1 - 2.2e-16 60.2 0.0 3.2e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG50384.1 - 0.0018 18.2 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 KR domain ASXH PF13919.6 KXG50385.1 - 1.1e-38 132.4 1.8 2.4e-38 131.3 1.8 1.6 1 0 0 1 1 1 1 Asx homology domain Longin PF13774.6 KXG50386.1 - 9.8e-26 89.6 0.7 1.5e-25 89.0 0.7 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KXG50386.1 - 2.5e-14 52.8 0.0 5e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin SLM4 PF16818.5 KXG50386.1 - 0.047 13.7 0.3 0.38 10.7 0.0 2.0 1 1 1 2 2 2 0 Protein SLM4 EMP24_GP25L PF01105.24 KXG50386.1 - 0.096 12.6 0.3 0.19 11.7 0.1 1.6 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Elong_Iki1 PF10483.9 KXG50387.1 - 1.7e-101 339.7 0.0 1.9e-101 339.5 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Alpha-amylase PF00128.24 KXG50388.1 - 5.5e-110 368.1 1.1 9.2e-110 367.3 0.3 1.6 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KXG50388.1 - 9.2e-05 22.5 0.0 0.00024 21.1 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Glyco_hydro_42C PF08533.10 KXG50388.1 - 0.039 13.7 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain hDGE_amylase PF14701.6 KXG50388.1 - 0.055 12.6 0.1 0.084 11.9 0.1 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Sugar_tr PF00083.24 KXG50389.1 - 3.2e-85 286.7 18.2 3.7e-85 286.5 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG50389.1 - 7e-18 64.7 27.0 3.4e-17 62.4 22.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily SNRNP27 PF08648.12 KXG50392.1 - 1.6e-25 88.9 2.4 3.1e-25 88.0 2.4 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Glyco_hydro_63 PF03200.16 KXG50393.1 - 1e-174 581.9 3.0 9.5e-174 578.7 3.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KXG50393.1 - 1.1e-88 297.1 0.0 3e-88 295.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain DAO PF01266.24 KXG50393.1 - 5.4e-68 230.1 0.1 8.1e-68 229.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG50393.1 - 5.3e-06 25.9 0.1 0.054 12.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG50393.1 - 1.1e-05 25.6 0.2 2.8e-05 24.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXG50393.1 - 4.8e-05 22.4 0.1 0.0012 17.8 0.1 2.3 1 1 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.27 KXG50393.1 - 0.00085 19.8 0.3 0.029 14.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trehalase PF01204.18 KXG50393.1 - 0.0013 17.6 1.7 0.0025 16.7 1.4 1.5 1 1 0 1 1 1 1 Trehalase NAD_binding_9 PF13454.6 KXG50393.1 - 0.0035 17.4 0.5 0.23 11.5 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Mqo PF06039.15 KXG50393.1 - 0.0052 15.4 0.0 0.024 13.2 0.0 1.9 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.17 KXG50393.1 - 0.0085 15.4 0.2 0.015 14.5 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KXG50393.1 - 0.028 13.5 0.4 3 6.8 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain MCRA PF06100.11 KXG50393.1 - 0.038 12.8 0.5 0.066 12.0 0.1 1.5 2 0 0 2 2 2 0 MCRA family FAD_oxidored PF12831.7 KXG50393.1 - 0.18 11.1 0.9 3.1 7.0 0.9 2.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 KXG50393.1 - 0.19 12.0 0.3 3 8.1 0.1 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain MMtag PF10159.9 KXG50394.1 - 1.1e-33 115.3 3.8 1.1e-33 115.3 3.8 1.6 2 0 0 2 2 2 1 Multiple myeloma tumor-associated CDC27 PF09507.10 KXG50394.1 - 0.053 12.9 2.2 0.069 12.5 2.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CRT10 PF08728.10 KXG50395.1 - 2.4e-19 69.0 0.0 1.1e-10 40.5 0.0 2.4 2 0 0 2 2 2 2 CRT10 IBR PF01485.21 KXG50397.1 - 1.4e-18 66.8 42.5 4.1e-15 55.8 5.2 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 KXG50397.1 - 3.1e-17 62.9 0.1 5.1e-17 62.2 0.1 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_5 PF14634.6 KXG50397.1 - 0.001 19.0 11.1 0.001 19.0 11.1 4.0 3 1 1 4 4 3 1 zinc-RING finger domain zf-RING_11 PF17123.5 KXG50397.1 - 0.0028 17.4 5.4 0.0028 17.4 5.4 2.5 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_2 PF13639.6 KXG50397.1 - 0.0055 17.0 10.3 0.0055 17.0 10.3 4.5 4 1 1 5 5 5 1 Ring finger domain DUF3402 PF11882.8 KXG50398.1 - 9e-194 644.8 0.0 1.4e-193 644.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KXG50398.1 - 4e-88 295.4 0.0 6e-88 294.8 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein PAP2 PF01569.21 KXG50398.1 - 1.3e-15 57.4 4.2 3.3e-15 56.0 2.1 2.4 2 0 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 KXG50398.1 - 0.0097 16.0 0.1 0.1 12.7 0.1 2.3 1 1 0 1 1 1 1 Divergent PAP2 family DUF4131 PF13567.6 KXG50398.1 - 0.1 12.2 0.1 0.25 11.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) TbpB_C PF17483.2 KXG50398.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B adh_short_C2 PF13561.6 KXG50399.1 - 6.8e-59 199.2 1.8 8e-59 199.0 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG50399.1 - 2.4e-40 138.1 0.2 2.9e-40 137.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG50399.1 - 1.7e-06 28.1 0.4 3e-06 27.3 0.4 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXG50399.1 - 0.0003 20.3 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family LDcluster4 PF18306.1 KXG50399.1 - 0.21 11.1 3.6 2.9 7.5 3.1 2.3 1 1 1 2 2 2 0 SLOG cluster4 family Oxidored_FMN PF00724.20 KXG50400.1 - 2.6e-97 326.2 0.0 3e-97 325.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NUC173 PF08161.12 KXG50400.1 - 0.23 11.1 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 NUC173 domain AATase PF07247.12 KXG50401.1 - 1.3e-12 47.1 0.0 2.4e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.16 KXG50401.1 - 0.0036 17.1 0.0 0.008 16.0 0.0 1.5 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Fungal_trans_2 PF11951.8 KXG50402.1 - 0.0021 17.0 0.3 0.0044 15.9 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.26 KXG50403.1 - 9.7e-10 38.5 0.0 1.8e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG50403.1 - 8.7e-09 35.2 0.1 4.2e-08 33.0 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXG50403.1 - 0.0065 17.5 0.0 0.012 16.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sugar_tr PF00083.24 KXG50405.1 - 5.5e-83 279.3 21.5 6.8e-83 279.0 21.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG50405.1 - 4.4e-25 88.4 34.8 1.8e-24 86.3 34.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG50405.1 - 2.4e-07 29.6 1.7 2.4e-07 29.6 1.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1129 PF06570.11 KXG50405.1 - 2.4 7.6 4.8 0.85 9.1 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Mso1_Sec1_bdg PF14475.6 KXG50406.1 - 5.3e-13 48.3 0.0 1.1e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ecl1 PF12855.7 KXG50406.1 - 0.55 11.4 9.1 0.94 10.6 9.1 1.4 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Ribosomal_L28e PF01778.17 KXG50407.1 - 1.9e-38 131.7 1.0 3.5e-38 130.9 1.0 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 KXG50407.1 - 2.8e-30 104.9 11.1 2.8e-30 104.9 11.1 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KXG50407.1 - 2.1e-06 27.4 14.9 2.7e-06 27.0 14.9 1.1 1 0 0 1 1 1 1 BUD22 CxC6 PF18721.1 KXG50407.1 - 0.16 12.3 0.4 0.38 11.1 0.2 1.7 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Drc1-Sld2 PF11719.8 KXG50407.1 - 0.46 10.0 11.1 0.63 9.5 11.1 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nop14 PF04147.12 KXG50407.1 - 1.7 6.8 23.6 2 6.5 23.6 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KXG50407.1 - 5.4 5.2 20.2 2.8 6.1 16.8 1.9 2 0 0 2 2 2 0 CDC45-like protein SAPS PF04499.15 KXG50407.1 - 7.7 5.2 7.9 10 4.8 7.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Abhydrolase_6 PF12697.7 KXG50408.1 - 1e-08 36.1 0.0 1.3e-08 35.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG50408.1 - 3.3e-08 33.1 0.0 5.7e-08 32.3 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXG50408.1 - 1.3e-07 31.3 0.0 2e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KXG50408.1 - 1.7e-07 31.1 0.0 2.5e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 KXG50408.1 - 3e-06 26.2 0.0 6e-06 25.1 0.0 1.4 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 KXG50408.1 - 3.2e-06 27.2 0.0 6.8e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 KXG50408.1 - 6.3e-05 22.6 0.0 0.00012 21.7 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXG50408.1 - 0.0012 18.6 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1100 PF06500.11 KXG50408.1 - 0.0019 17.1 0.0 0.0025 16.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_2 PF02230.16 KXG50408.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PHB_depo_C PF06850.11 KXG50408.1 - 0.029 13.8 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 PHB de-polymerase C-terminus Abhydrolase_3 PF07859.13 KXG50408.1 - 0.033 14.1 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 KXG50409.1 - 1.5e-30 106.5 0.0 2.1e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXG50409.1 - 1.9e-05 25.4 0.9 2.3e-05 25.1 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXG50409.1 - 0.00049 20.0 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KXG50409.1 - 0.0013 18.5 0.0 0.0028 17.3 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold MFS_1 PF07690.16 KXG50410.1 - 3.2e-12 46.1 23.2 8.7e-06 24.9 2.9 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG50410.1 - 1e-10 40.7 1.5 1.1e-10 40.6 0.3 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_4 PF01565.23 KXG50411.1 - 1.1e-22 80.3 2.6 2.2e-22 79.3 2.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG50411.1 - 8.2e-08 32.2 0.4 1.7e-07 31.2 0.4 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KXG50411.1 - 0.0057 16.1 0.2 0.027 13.8 0.1 1.8 2 0 0 2 2 2 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding adh_short PF00106.25 KXG50412.1 - 1e-26 93.7 0.4 1.4e-26 93.2 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG50412.1 - 1.5e-19 70.5 1.5 1.8e-19 70.2 1.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG50412.1 - 6.2e-08 32.8 0.1 8.1e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXG50412.1 - 2.6e-06 27.5 0.4 3.5e-06 27.0 0.5 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXG50412.1 - 0.00093 18.7 0.2 0.0034 16.9 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG50412.1 - 0.038 13.4 0.0 0.13 11.6 0.0 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXG50412.1 - 0.054 13.0 0.1 0.084 12.4 0.1 1.4 1 1 0 1 1 1 0 NmrA-like family p450 PF00067.22 KXG50413.1 - 6.6e-61 206.5 0.0 8.8e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 KXG50414.1 - 1.2e-62 211.7 0.1 1.2e-62 211.7 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXG50414.1 - 8.1e-53 179.0 1.7 1.9e-52 177.8 1.7 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KXG50414.1 - 2e-52 178.3 0.0 3.5e-52 177.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXG50414.1 - 4.5e-48 164.4 0.0 8.6e-48 163.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXG50414.1 - 2e-35 121.3 0.4 6e-35 119.8 0.4 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXG50414.1 - 1.5e-18 67.2 0.0 4.2e-18 65.8 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KXG50414.1 - 2.2e-18 67.6 0.0 8.3e-18 65.7 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXG50414.1 - 6.9e-13 48.7 1.7 6.6e-12 45.5 0.0 3.3 4 0 0 4 4 3 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXG50414.1 - 1.1e-08 34.8 2.0 7.4e-08 32.1 1.1 2.6 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 KXG50414.1 - 4.6e-06 26.9 0.0 1.2e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KXG50414.1 - 2.7e-05 24.0 0.1 7.8e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 KXG50414.1 - 6e-05 22.7 0.8 6e-05 22.7 0.8 2.3 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase SAT PF16073.5 KXG50414.1 - 0.0025 17.6 0.1 0.023 14.4 0.1 2.2 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 KXG50414.1 - 0.0028 17.5 0.2 0.0099 15.7 0.2 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_25 PF13649.6 KXG50414.1 - 0.0096 16.6 0.0 0.041 14.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG50414.1 - 0.036 14.8 0.1 0.1 13.3 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXG50414.1 - 0.042 14.5 0.0 0.15 12.7 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_1 PF00561.20 KXG50415.1 - 1.2e-07 31.6 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG50415.1 - 6.4e-06 26.9 1.2 7.4e-06 26.7 1.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG50415.1 - 0.0001 21.7 0.0 0.00017 20.9 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KXG50415.1 - 0.028 14.3 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase BAAT_C PF08840.11 KXG50415.1 - 0.2 11.6 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PhoLip_ATPase_C PF16212.5 KXG50416.1 - 1.4e-47 162.6 7.2 1.4e-47 162.6 7.2 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXG50416.1 - 1.1e-16 60.3 1.2 2.3e-16 59.2 1.2 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KXG50416.1 - 1.2e-13 51.8 1.0 1.3e-07 32.1 0.3 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXG50416.1 - 3.8e-08 33.3 0.1 9.5e-07 28.8 0.0 2.6 2 1 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KXG50416.1 - 1.8e-07 30.9 3.3 0.0014 18.2 0.0 3.5 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase_3 PF08282.12 KXG50416.1 - 0.0011 18.8 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HIGH_NTase1_ass PF16581.5 KXG50416.1 - 0.092 12.7 0.1 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region Sec16_C PF12931.7 KXG50417.1 - 9.2e-109 363.7 0.0 1.3e-108 363.2 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.7 KXG50417.1 - 3e-65 220.7 21.4 3e-65 220.7 21.4 4.0 3 1 0 3 3 3 2 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.7 KXG50417.1 - 1.1e-33 116.4 0.0 2.5e-33 115.1 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Hus1 PF04005.12 KXG50418.1 - 1.2e-92 310.2 0.0 1.5e-92 309.9 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Hexokinase_2 PF03727.16 KXG50419.1 - 3.5e-71 239.4 0.0 4.4e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXG50419.1 - 5.3e-66 222.3 0.0 8.4e-66 221.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase GAS2 PF02187.17 KXG50420.1 - 3.2e-06 27.1 0.1 7.5e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Cas3_C PF18395.1 KXG50420.1 - 0.032 14.7 0.2 4.9 7.7 0.0 2.9 2 0 0 2 2 2 0 Cas3 C-terminal domain RabGAP-TBC PF00566.18 KXG50422.1 - 3.2e-41 141.3 1.1 7.8e-41 140.1 1.1 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KXG50422.1 - 6.2e-06 25.8 0.0 0.049 13.1 0.0 3.3 2 1 0 2 2 2 2 Rab-binding domain (RBD) Ring_hydroxyl_A PF00848.19 KXG50423.1 - 6.3e-22 78.6 4.6 1.3e-09 38.3 0.0 3.8 2 2 2 4 4 4 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KXG50423.1 - 1.8e-17 63.0 0.0 1.6e-16 60.0 0.0 2.4 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain Sigma_reg_N PF13800.6 KXG50423.1 - 0.14 12.4 0.2 0.61 10.4 0.1 2.0 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Ank_2 PF12796.7 KXG50424.1 - 4.6e-06 27.1 0.1 0.0014 19.2 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG50424.1 - 0.14 12.8 0.7 6.3 7.7 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat Polysacc_lyase PF14099.6 KXG50425.1 - 4.2e-54 183.6 11.0 4.8e-54 183.4 11.0 1.0 1 0 0 1 1 1 1 Polysaccharide lyase DUF1080 PF06439.11 KXG50425.1 - 0.00051 20.2 4.0 0.00077 19.6 4.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Phage_sheath_1N PF17481.2 KXG50425.1 - 0.039 14.4 0.0 0.053 14.0 0.0 1.5 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain Triabin PF03973.13 KXG50425.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Triabin F-box PF00646.33 KXG50426.1 - 0.12 12.2 0.0 0.43 10.5 0.0 1.9 1 0 0 1 1 1 0 F-box domain MFS_1 PF07690.16 KXG50427.1 - 1.3e-36 126.2 22.7 1.4e-27 96.5 0.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG50427.1 - 9.6e-12 44.5 7.8 7.2e-10 38.3 0.3 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 KXG50427.1 - 0.00074 18.9 2.6 0.00074 18.9 2.6 2.6 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KXG50427.1 - 0.003 16.5 6.2 0.003 16.5 6.2 3.2 2 2 0 2 2 2 1 MFS_1 like family Transferase PF02458.15 KXG50428.1 - 4.6e-18 65.1 0.0 5.4e-17 61.6 0.0 1.9 1 1 0 1 1 1 1 Transferase family FSH1 PF03959.13 KXG50429.1 - 1.5e-14 54.2 0.0 1.8e-13 50.6 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ketoacyl-synt PF00109.26 KXG50430.1 - 4.9e-60 203.2 0.0 8.8e-60 202.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXG50430.1 - 3.2e-57 193.4 1.3 6.6e-57 192.3 0.6 2.0 2 0 0 2 2 1 1 KR domain Acyl_transf_1 PF00698.21 KXG50430.1 - 2.1e-48 165.5 0.1 4e-48 164.6 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXG50430.1 - 4.2e-44 151.0 0.8 7.8e-44 150.1 0.8 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KXG50430.1 - 2.9e-38 130.5 0.2 7.9e-38 129.1 0.0 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KXG50430.1 - 5.1e-20 72.1 0.0 1.8e-19 70.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXG50430.1 - 1.7e-18 67.1 0.0 1.2e-10 41.9 0.0 2.9 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 KXG50430.1 - 1.2e-14 54.4 0.0 3.4e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KXG50430.1 - 1.7e-12 47.5 0.3 1.4e-11 44.5 0.1 2.7 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KXG50430.1 - 3e-12 46.7 0.1 1.1e-11 44.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KXG50430.1 - 5.5e-11 43.7 0.0 1.6e-09 38.9 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXG50430.1 - 7.3e-11 41.9 0.4 2.5e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KXG50430.1 - 1.1e-10 42.1 0.0 5.1e-10 39.9 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG50430.1 - 9e-10 39.1 0.0 4.1e-09 37.0 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 KXG50430.1 - 5.2e-09 36.3 0.1 1.7e-08 34.7 0.0 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KXG50430.1 - 5.4e-06 26.1 0.8 2.4e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 KXG50430.1 - 6.8e-06 25.6 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.10 KXG50430.1 - 0.00053 19.8 0.3 0.0032 17.3 0.3 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NodS PF05401.11 KXG50430.1 - 0.0013 18.4 0.0 0.0074 15.9 0.0 2.3 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 KXG50430.1 - 0.0016 18.2 0.0 0.004 16.9 0.0 1.6 1 1 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 KXG50430.1 - 0.0025 17.6 0.0 0.0084 15.9 0.0 1.9 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Thiolase_N PF00108.23 KXG50430.1 - 0.012 15.0 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Sacchrp_dh_NADP PF03435.18 KXG50430.1 - 0.032 14.5 0.2 0.68 10.2 0.0 2.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_28 PF02636.17 KXG50430.1 - 0.042 13.5 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 KXG50430.1 - 0.16 11.2 0.0 0.38 10.0 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase domain SRP-alpha_N PF04086.13 KXG50431.1 - 2.4e-78 264.0 0.0 3.2e-78 263.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KXG50431.1 - 1e-50 172.1 0.0 1.7e-50 171.4 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KXG50431.1 - 1.3e-09 38.1 0.0 3.7e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KXG50431.1 - 1.2e-07 31.0 0.0 2.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KXG50431.1 - 0.0004 20.2 0.0 0.00074 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXG50431.1 - 0.0037 17.0 0.1 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXG50431.1 - 0.011 16.2 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 KXG50431.1 - 0.018 15.1 0.0 0.089 12.8 0.0 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 KXG50431.1 - 0.045 13.8 0.1 0.5 10.5 0.1 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_31 PF13614.6 KXG50431.1 - 0.051 13.5 0.1 0.44 10.4 0.0 2.0 1 1 1 2 2 2 0 AAA domain Fer4_NifH PF00142.18 KXG50431.1 - 0.076 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_33 PF13671.6 KXG50431.1 - 0.1 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXG50431.1 - 0.11 13.1 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 KXG50431.1 - 0.12 12.8 0.0 0.38 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain YIF1 PF03878.15 KXG50432.1 - 5.5e-99 330.5 3.8 6.5e-99 330.3 3.8 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KXG50432.1 - 1.7e-05 24.6 5.7 1.7e-05 24.6 5.7 1.5 2 0 0 2 2 2 1 Yip1 domain DUF4271 PF14093.6 KXG50432.1 - 0.12 12.2 4.4 0.25 11.2 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) Ribosomal_L14e PF01929.17 KXG50433.1 - 1.7e-27 95.7 0.3 2.6e-27 95.1 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KXG50433.1 - 1.4e-07 31.2 0.2 2.7e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 KOW motif NAC PF01849.18 KXG50434.1 - 4.7e-22 77.7 0.0 8.8e-21 73.6 0.0 2.2 2 0 0 2 2 2 1 NAC domain NESP55 PF06390.12 KXG50434.1 - 0.003 17.2 4.0 0.003 17.2 4.0 1.6 2 0 0 2 2 2 1 Neuroendocrine-specific golgi protein P55 (NESP55) CENP-B_dimeris PF09026.10 KXG50434.1 - 0.1 13.0 7.5 9.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Mt_ATP-synt_D PF05873.12 KXG50435.1 - 6.3e-24 84.6 1.5 7.9e-24 84.3 1.5 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) LXG PF04740.12 KXG50435.1 - 0.029 14.1 4.0 0.082 12.6 2.0 1.8 1 1 1 2 2 2 0 LXG domain of WXG superfamily CheZ PF04344.13 KXG50435.1 - 0.036 14.0 1.4 0.053 13.4 0.9 1.4 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ T2SSM_b PF10741.9 KXG50435.1 - 0.038 13.8 0.3 0.097 12.5 0.0 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b E3_UbLigase_R4 PF13764.6 KXG50435.1 - 0.067 11.3 0.3 0.075 11.2 0.3 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 DUF948 PF06103.11 KXG50435.1 - 0.08 13.2 3.1 0.5 10.7 0.3 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ATPase PF06745.13 KXG50435.1 - 0.089 12.1 0.3 0.13 11.6 0.3 1.3 1 0 0 1 1 1 0 KaiC DUF2408 PF10303.9 KXG50435.1 - 0.13 12.8 1.9 0.2 12.2 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Tropomyosin PF00261.20 KXG50435.1 - 0.24 10.7 4.9 1.1 8.5 0.1 2.1 1 1 0 2 2 2 0 Tropomyosin Spectrin PF00435.21 KXG50435.1 - 0.26 11.8 5.0 1.6 9.3 1.4 2.3 1 1 0 2 2 2 0 Spectrin repeat FlaC_arch PF05377.11 KXG50435.1 - 0.61 10.5 3.0 7.3 7.1 0.5 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Aldedh PF00171.22 KXG50438.1 - 5.9e-119 397.6 0.0 7.5e-119 397.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2681 PF10883.8 KXG50438.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) HhH-GPD PF00730.25 KXG50439.1 - 1.2e-05 25.7 0.0 2.9e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KXG50439.1 - 0.009 15.8 0.5 0.044 13.7 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KXG50439.1 - 0.013 16.1 0.1 0.27 11.9 0.0 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix domain DUF2400 PF09674.10 KXG50439.1 - 0.1 12.6 0.0 11 5.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2400) GATase_6 PF13522.6 KXG50440.1 - 1.9e-13 50.7 0.0 5.8e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KXG50440.1 - 1.2e-10 41.4 0.0 2.4e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KXG50440.1 - 3.7e-07 29.8 0.0 1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KXG50440.1 - 4.1e-05 22.6 0.0 9.8e-05 21.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.6 KXG50440.1 - 0.048 13.2 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 Phosphoribosyl transferase DNA_photolyase PF00875.18 KXG50440.1 - 0.14 12.1 0.0 0.47 10.4 0.0 1.8 2 0 0 2 2 2 0 DNA photolyase DNA_methylase PF00145.17 KXG50441.1 - 6.4e-39 134.2 0.0 1.9e-26 93.2 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase MmgE_PrpD PF03972.14 KXG50442.1 - 5.9e-147 489.7 0.0 6.8e-147 489.6 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF1266 PF06889.11 KXG50442.1 - 0.058 13.4 0.1 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) Glyco_hydro_28 PF00295.17 KXG50443.1 - 3.4e-52 177.5 13.8 4.5e-52 177.1 13.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KXG50443.1 - 0.0042 17.0 8.7 0.013 15.4 8.5 2.0 1 1 0 1 1 1 1 Right handed beta helix region RACo_C_ter PF14574.6 KXG50443.1 - 0.12 11.4 1.0 8.8 5.3 0.1 2.2 2 0 0 2 2 2 0 C-terminal domain of RACo the ASKHA domain Pectinesterase PF01095.19 KXG50444.1 - 1.4e-52 178.2 5.1 1.9e-52 177.9 5.1 1.0 1 0 0 1 1 1 1 Pectinesterase DUF4402 PF14352.6 KXG50444.1 - 0.012 16.3 2.1 0.029 15.0 2.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) dCMP_cyt_deam_1 PF00383.23 KXG50445.1 - 6.4e-05 22.8 0.0 8.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KXG50445.1 - 0.031 13.9 0.1 5.9 6.4 0.0 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases MOFRL PF05161.13 KXG50445.1 - 0.18 12.0 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 MOFRL family E1-E2_ATPase PF00122.20 KXG50446.1 - 8.7e-38 129.6 15.1 2.5e-30 105.3 0.0 3.6 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXG50446.1 - 7.7e-25 87.7 8.6 7.7e-25 87.7 8.6 2.9 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXG50446.1 - 3.2e-20 73.3 0.1 6.7e-15 55.9 0.1 3.7 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXG50446.1 - 4.4e-18 64.7 0.0 9.5e-18 63.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KXG50446.1 - 1e-15 57.6 0.0 2e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXG50446.1 - 7.3e-05 22.6 0.3 0.011 15.5 0.3 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DctM PF06808.12 KXG50446.1 - 0.00037 19.4 8.2 0.0031 16.4 0.3 2.9 3 0 0 3 3 3 2 Tripartite ATP-independent periplasmic transporter, DctM component DUF2463 PF09591.10 KXG50446.1 - 0.076 12.9 0.4 0.16 11.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) Aminotran_1_2 PF00155.21 KXG50447.1 - 1.8e-34 119.5 0.0 2.2e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 KXG50447.1 - 0.00032 19.6 0.0 0.00048 19.0 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 KXG50447.1 - 0.005 15.8 0.0 0.93 8.4 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXG50447.1 - 0.11 11.1 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 KXG50448.1 - 2.8e-35 121.7 0.0 3.6e-17 62.1 0.0 3.0 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 KXG50448.1 - 2.6e-22 79.6 0.0 5e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Peptidase_M28 PF04389.17 KXG50448.1 - 3.8e-17 62.6 0.0 9.2e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 KXG50448.1 - 1.2e-15 57.7 0.0 3.5e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 KXG50448.1 - 7e-07 29.2 0.0 2.1e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 PA domain DIOX_N PF14226.6 KXG50449.1 - 2.8e-18 66.8 0.0 4.4e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG50449.1 - 3.7e-14 53.0 0.0 7e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KXG50450.1 - 1.8e-33 116.0 10.9 2.5e-33 115.5 10.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KXG50450.1 - 1.3e-06 27.0 0.2 0.00022 19.7 0.1 2.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KXG50450.1 - 2.2e-06 26.8 5.9 2.2e-06 26.8 5.9 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 KXG50450.1 - 3.5e-05 22.6 16.2 7.6e-05 21.4 6.9 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein CLN3 PF02487.17 KXG50450.1 - 0.21 10.6 2.9 4 6.4 0.3 2.3 2 0 0 2 2 2 0 CLN3 protein DUF5510 PF17629.2 KXG50450.1 - 0.25 11.3 2.0 0.44 10.5 0.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5510) MFS_3 PF05977.13 KXG50450.1 - 1 7.7 11.7 0.9 7.9 0.3 2.5 2 1 0 2 2 2 0 Transmembrane secretion effector MFS_1_like PF12832.7 KXG50450.1 - 1.2 8.0 11.2 0.38 9.6 0.3 3.0 2 1 1 3 3 3 0 MFS_1 like family MFS_1 PF07690.16 KXG50451.1 - 9.4e-44 149.8 55.3 1.5e-34 119.5 34.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG50451.1 - 9.4e-17 61.0 10.5 9.4e-17 61.0 10.5 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KXG50451.1 - 1.5e-15 56.7 18.6 2.1e-15 56.2 18.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) 7tm_4 PF13853.6 KXG50451.1 - 0.00084 19.2 0.5 0.0023 17.7 0.1 1.9 2 0 0 2 2 2 1 Olfactory receptor PUCC PF03209.15 KXG50451.1 - 0.18 10.7 21.2 0.17 10.8 11.6 2.5 2 0 0 2 2 2 0 PUCC protein p450 PF00067.22 KXG50452.1 - 1e-47 163.0 0.0 1.4e-47 162.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TauD PF02668.16 KXG50453.1 - 3.4e-12 46.7 0.4 3.7e-05 23.7 0.1 2.2 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXG50453.1 - 0.025 13.7 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 CsiD Glyco_hydro_12 PF01670.16 KXG50455.1 - 3.8e-42 144.7 7.4 4.5e-42 144.5 7.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Sugar_tr PF00083.24 KXG50456.1 - 2.1e-37 129.0 13.9 3.4e-20 72.4 0.3 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter Glyco_hydro_3_C PF01915.22 KXG50456.1 - 1.1e-19 71.2 0.1 1.9e-19 70.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KXG50456.1 - 1.5e-19 69.9 0.0 2.9e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 KXG50456.1 - 2.4e-19 69.9 0.0 3.1e-09 36.6 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain MFS_1 PF07690.16 KXG50456.1 - 2.1e-10 40.1 11.3 2.8e-08 33.1 7.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG50456.1 - 0.0025 16.3 2.7 0.0037 15.8 2.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar-bind PF04198.13 KXG50456.1 - 0.098 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain GMC_oxred_N PF00732.19 KXG50457.1 - 6.3e-43 147.2 0.0 1.1e-42 146.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG50457.1 - 2.8e-30 105.8 0.0 4.4e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_4 PF01565.23 KXG50458.1 - 2.5e-16 59.7 0.1 3.9e-16 59.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 KXG50458.1 - 0.00019 21.4 0.6 0.00019 21.4 0.6 1.8 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase Aa_trans PF01490.18 KXG50459.1 - 1.5e-40 139.2 31.3 1.8e-40 138.9 31.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KXG50459.1 - 0.0045 16.1 17.9 0.01 14.9 17.9 1.7 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family GWT1 PF06423.12 KXG50459.1 - 0.45 10.6 5.5 0.37 10.9 2.5 2.3 2 1 0 2 2 2 0 GWT1 CAAD PF14159.6 KXG50459.1 - 0.98 9.3 6.4 0.5 10.2 0.2 3.3 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase FAD_binding_4 PF01565.23 KXG50460.1 - 3.4e-21 75.4 1.9 3.4e-21 75.4 1.9 2.0 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.12 KXG50460.1 - 2.5e-10 40.3 0.5 6.3e-10 39.0 0.5 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF3425 PF11905.8 KXG50462.1 - 3.8e-21 75.3 0.2 8.1e-21 74.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.25 KXG50463.1 - 8.1e-32 110.3 0.0 1.2e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG50463.1 - 1.4e-21 77.1 0.0 2e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG50463.1 - 8.1e-05 22.6 0.3 0.0027 17.6 0.0 2.5 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 KXG50463.1 - 0.0091 15.5 0.0 0.033 13.7 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Abhydrolase_6 PF12697.7 KXG50464.1 - 5e-06 27.3 0.2 3.4e-05 24.5 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KXG50464.1 - 0.00022 20.8 0.0 0.0027 17.3 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KXG50464.1 - 0.00026 20.7 0.1 0.00039 20.1 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 KXG50464.1 - 0.00049 18.9 0.1 0.2 10.3 0.1 2.1 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) DUF1100 PF06500.11 KXG50464.1 - 0.0047 15.8 0.0 0.0065 15.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Hydrolase_4 PF12146.8 KXG50464.1 - 0.031 13.5 0.0 0.34 10.1 0.0 2.5 1 1 1 2 2 2 0 Serine aminopeptidase, S33 BAAT_C PF08840.11 KXG50464.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal FA_hydroxylase PF04116.13 KXG50465.1 - 6.4e-23 81.6 16.1 6.4e-23 81.6 16.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily BATS PF06968.13 KXG50466.1 - 1e-22 80.0 0.2 4.6e-22 78.0 0.0 2.1 2 1 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KXG50466.1 - 1.5e-15 58.0 0.0 1.3e-14 54.9 0.1 2.1 2 0 0 2 2 2 1 Radical SAM superfamily AMP-binding PF00501.28 KXG50467.1 - 2.3e-73 247.2 0.0 2.9e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG50467.1 - 5.8e-06 27.2 0.0 1.7e-05 25.7 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Citrate_synt PF00285.21 KXG50468.1 - 3.6e-95 319.1 0.0 4.4e-95 318.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain ABC_tran PF00005.27 KXG50469.1 - 6.7e-48 162.7 0.0 3.7e-26 92.3 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXG50469.1 - 2.1e-15 57.3 4.1 1.1e-05 25.4 0.0 4.2 2 2 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXG50469.1 - 1.5e-11 44.2 0.1 0.0019 17.7 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Chromo PF00385.24 KXG50469.1 - 3e-08 33.4 0.0 5.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 KXG50469.1 - 1.4e-06 28.4 0.0 0.03 14.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KXG50469.1 - 3.1e-06 27.9 4.0 0.011 16.3 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KXG50469.1 - 4.4e-06 26.4 1.1 0.054 13.2 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXG50469.1 - 2.1e-05 24.5 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 KXG50469.1 - 0.00034 20.8 2.1 0.29 11.2 0.4 3.5 4 0 0 4 4 4 1 Helicase HerA, central domain AAA_15 PF13175.6 KXG50469.1 - 0.00038 20.3 0.1 0.46 10.1 0.2 2.4 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 KXG50469.1 - 0.0004 20.3 0.1 0.089 12.7 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KXG50469.1 - 0.00088 19.6 0.1 0.2 12.0 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXG50469.1 - 0.00088 19.5 0.0 0.18 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KXG50469.1 - 0.0025 17.9 0.0 0.29 11.2 0.0 3.3 4 0 0 4 4 4 1 Dynamin family SbcCD_C PF13558.6 KXG50469.1 - 0.0028 17.9 0.0 1.3 9.3 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 KXG50469.1 - 0.0032 17.8 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KXG50469.1 - 0.011 15.4 0.2 1.3 8.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXG50469.1 - 0.014 15.5 0.1 3.9 7.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain MeaB PF03308.16 KXG50469.1 - 0.019 14.0 0.1 5.7 5.8 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DNA_ligase_OB_2 PF14743.6 KXG50469.1 - 0.023 14.7 0.3 0.069 13.2 0.3 1.8 1 0 0 1 1 1 0 DNA ligase OB-like domain AAA_30 PF13604.6 KXG50469.1 - 0.025 14.3 0.3 9 6.0 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KXG50469.1 - 0.025 15.0 0.0 1.3 9.5 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXG50469.1 - 0.027 15.0 0.0 8.5 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KXG50469.1 - 0.04 13.7 0.0 7.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 KXG50469.1 - 0.046 13.0 0.0 9.1 5.5 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_13 PF13166.6 KXG50469.1 - 0.047 12.3 0.0 2.2 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KXG50469.1 - 0.05 12.7 0.0 6.8 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ALF PF03752.13 KXG50469.1 - 0.11 12.5 6.6 5.1 7.2 0.3 3.7 3 0 0 3 3 3 0 Short repeats of unknown function CLASP_N PF12348.8 KXG50469.1 - 0.11 12.1 0.1 1 8.9 0.3 2.2 2 0 0 2 2 2 0 CLASP N terminal Roc PF08477.13 KXG50469.1 - 0.12 12.6 0.0 29 4.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MukB PF04310.12 KXG50469.1 - 0.13 12.1 0.1 17 5.1 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal TsaE PF02367.17 KXG50469.1 - 0.14 12.2 0.3 22 5.0 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KXG50469.1 - 0.18 11.0 1.3 0.51 9.5 0.0 2.3 3 0 0 3 3 2 0 NB-ARC domain HEAT_EZ PF13513.6 KXG50469.1 - 0.19 12.2 0.9 3.8 8.1 0.1 3.4 3 0 0 3 3 2 0 HEAT-like repeat AAA_27 PF13514.6 KXG50469.1 - 0.21 11.2 1.8 7.9 6.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain CLP1_P PF16575.5 KXG50469.1 - 0.49 10.2 2.8 24 4.7 0.0 3.3 4 0 0 4 4 4 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ABC_tran_Xtn PF12848.7 KXG50469.1 - 5.6 7.1 6.7 2.8 8.0 0.3 2.6 2 0 0 2 2 2 0 ABC transporter Glyco_hydro_3_C PF01915.22 KXG50471.1 - 1.7e-43 149.0 0.0 3e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXG50471.1 - 1.1e-37 130.1 0.0 1.7e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXG50471.1 - 2.3e-21 75.7 0.0 5e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Malate_synthase PF01274.22 KXG50473.1 - 4.3e-231 767.7 0.0 4.9e-231 767.6 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Gln-synt_C PF00120.24 KXG50474.1 - 4.9e-82 275.7 0.0 6.1e-82 275.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short_C2 PF13561.6 KXG50475.1 - 1.8e-59 201.2 0.1 3.2e-59 200.3 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG50475.1 - 9.3e-40 136.2 0.1 1.3e-39 135.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG50475.1 - 5.4e-08 32.9 0.4 9.6e-08 32.1 0.4 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXG50475.1 - 0.0025 17.7 0.1 0.0052 16.7 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KXG50475.1 - 0.0064 17.2 0.0 0.014 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain THF_DHG_CYH_C PF02882.19 KXG50475.1 - 0.028 13.7 0.1 0.071 12.4 0.0 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 KXG50475.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RecC_C PF17946.1 KXG50475.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 RecC C-terminal domain Epimerase PF01370.21 KXG50475.1 - 0.12 11.8 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Tannase PF07519.11 KXG50476.1 - 1.8e-18 66.7 1.2 2.3e-18 66.4 1.2 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Pro_racemase PF05544.11 KXG50478.1 - 6.4e-90 301.5 0.1 7.2e-90 301.3 0.1 1.0 1 0 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.16 KXG50478.1 - 0.059 12.8 0.1 0.079 12.4 0.1 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein Aa_trans PF01490.18 KXG50479.1 - 2e-40 138.8 32.0 2.3e-40 138.6 32.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4134 PF13572.6 KXG50479.1 - 0.026 14.8 1.9 0.026 14.8 1.9 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4134) GNVR PF13807.6 KXG50479.1 - 1.2 9.1 0.0 1.2 9.1 0.0 2.5 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase DUF5336 PF17270.2 KXG50479.1 - 1.9 8.1 6.2 5.5 6.6 6.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5336) AA_permease_2 PF13520.6 KXG50480.1 - 1.9e-43 148.9 49.5 2.5e-43 148.5 49.5 1.0 1 0 0 1 1 1 1 Amino acid permease LPMO_10 PF03067.15 KXG50481.1 - 4.4e-12 47.1 5.7 9.6e-12 46.0 5.7 1.6 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Pyr_redox_2 PF07992.14 KXG50483.1 - 3.3e-08 33.1 0.0 4e-06 26.3 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXG50483.1 - 4.7e-08 31.9 0.0 9.6e-07 27.6 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXG50483.1 - 1.3e-07 31.1 0.0 0.00011 21.4 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXG50483.1 - 1.5e-06 28.3 2.6 0.0083 16.1 0.1 4.0 3 2 0 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXG50483.1 - 3.9e-06 27.0 0.0 0.00024 21.3 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXG50483.1 - 0.00016 21.0 0.0 0.0057 15.9 0.0 2.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG50483.1 - 0.00092 18.9 0.1 2 7.9 0.0 3.1 2 1 0 3 3 3 2 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KXG50483.1 - 0.005 16.9 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KXG50483.1 - 0.027 13.8 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Viral_RdRp_C PF17501.2 KXG50483.1 - 0.077 13.5 0.2 2.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Viral RNA-directed RNA polymerase Sugar_tr PF00083.24 KXG50484.1 - 1.9e-131 439.1 27.9 2.2e-131 438.9 27.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG50484.1 - 5.2e-29 101.3 53.2 2.5e-24 85.9 33.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1689 PF07954.11 KXG50484.1 - 0.0047 17.3 0.2 0.15 12.5 0.0 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1689) TRI12 PF06609.13 KXG50484.1 - 0.024 13.1 10.0 0.074 11.5 4.9 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Cytochrom_B_C PF00032.17 KXG50484.1 - 2.6 8.4 7.0 2.9 8.2 3.1 2.6 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD Dioxygenase_C PF00775.21 KXG50485.1 - 9.5e-07 28.4 0.4 2.3e-06 27.2 0.1 1.7 2 0 0 2 2 2 1 Dioxygenase Rad4 PF03835.15 KXG50486.1 - 6.5e-35 120.0 0.0 1.9e-34 118.4 0.0 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KXG50486.1 - 1.2e-28 99.3 0.1 2.4e-28 98.3 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KXG50486.1 - 3.3e-14 52.4 0.0 7.3e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KXG50486.1 - 1.5e-13 51.5 0.3 1.5e-13 51.5 0.3 3.8 5 0 0 5 5 5 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KXG50486.1 - 0.0009 19.7 0.0 0.0029 18.0 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily Colicin_Pyocin PF01320.18 KXG50486.1 - 0.087 12.9 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein MHC_I_C PF06623.11 KXG50486.1 - 7.3 6.6 6.2 2.1 8.3 0.0 2.8 3 0 0 3 3 3 0 MHC_I C-terminus Secretin PF00263.21 KXG50488.1 - 0.051 13.2 1.1 3 7.5 0.3 3.1 3 0 0 3 3 3 0 Bacterial type II and III secretion system protein HAUS6_N PF14661.6 KXG50489.1 - 1.5e-40 139.2 0.0 2.4e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Trypan_PARP PF05887.11 KXG50489.1 - 0.015 15.3 11.2 0.028 14.4 11.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HD_3 PF13023.6 KXG50490.1 - 5.2e-49 166.3 0.3 6.3e-49 166.1 0.3 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KXG50490.1 - 8e-14 51.8 0.3 1.1e-13 51.4 0.3 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HIT PF01230.23 KXG50491.1 - 4e-24 85.2 0.2 8.6e-24 84.1 0.2 1.5 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXG50491.1 - 1.7e-05 25.2 0.1 2.7e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 KXG50491.1 - 0.048 13.4 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Mob1_phocein PF03637.17 KXG50492.1 - 1e-19 71.2 1.1 1.5e-19 70.6 1.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 KXG50492.1 - 5.7 7.3 8.3 0.62 10.4 3.6 1.8 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases cobW PF02492.19 KXG50493.1 - 1.3e-48 164.9 0.1 1.8e-48 164.5 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KXG50493.1 - 3e-05 24.0 0.1 0.23 11.4 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase CobW_C PF07683.14 KXG50493.1 - 0.00056 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 KXG50493.1 - 0.0099 16.3 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 KXG50493.1 - 0.013 15.3 2.5 0.24 11.2 2.5 2.2 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KXG50493.1 - 0.017 14.7 0.8 3.6 7.1 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXG50493.1 - 0.019 15.0 0.0 0.042 13.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase MeaB PF03308.16 KXG50493.1 - 0.037 13.0 0.5 1.9 7.4 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 KXG50493.1 - 0.039 13.0 0.0 0.071 12.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KXG50493.1 - 0.042 13.6 0.2 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KXG50493.1 - 0.043 14.3 0.0 0.078 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KXG50493.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KXG50493.1 - 0.081 12.9 0.2 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KXG50493.1 - 0.11 13.0 0.0 0.29 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXG50493.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXG50493.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 KXG50493.1 - 0.16 12.5 0.1 0.49 10.9 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Pkinase_Tyr PF07714.17 KXG50494.1 - 4e-09 36.1 0.0 3.4e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXG50494.1 - 4.9e-09 35.9 0.0 7.1e-08 32.1 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Lon_C PF05362.13 KXG50495.1 - 3.9e-64 216.0 0.0 7.2e-64 215.1 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KXG50495.1 - 8.3e-32 110.8 0.0 1.7e-31 109.7 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KXG50495.1 - 8.6e-22 78.0 0.0 1.9e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXG50495.1 - 2.2e-07 30.9 0.0 4.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KXG50495.1 - 3.3e-06 26.9 0.0 7.6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 KXG50495.1 - 5.5e-06 26.6 0.0 1.5e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 KXG50495.1 - 7.1e-06 25.2 0.2 1.6e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_22 PF13401.6 KXG50495.1 - 9.5e-06 25.9 0.1 0.00012 22.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXG50495.1 - 0.00012 22.5 1.1 0.00072 20.0 0.1 2.6 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KXG50495.1 - 0.00019 21.2 0.0 0.00056 19.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KXG50495.1 - 0.003 18.1 0.8 0.027 15.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KXG50495.1 - 0.0059 16.6 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DNTTIP1_dimer PF18192.1 KXG50495.1 - 0.016 15.5 1.1 3 8.3 0.1 3.0 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain IstB_IS21 PF01695.17 KXG50495.1 - 0.022 14.5 0.0 0.058 13.1 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 KXG50495.1 - 0.024 14.4 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXG50495.1 - 0.054 12.7 0.0 0.56 9.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 KXG50495.1 - 0.062 13.2 0.2 0.56 10.1 0.0 2.4 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.22 KXG50495.1 - 0.066 13.6 0.0 0.21 12.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase DUF4276 PF14103.6 KXG50495.1 - 0.071 13.3 0.2 0.18 12.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) RsgA_GTPase PF03193.16 KXG50495.1 - 0.089 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 KXG50495.1 - 0.14 12.7 1.8 0.41 11.2 0.1 2.3 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 KXG50495.1 - 0.17 11.4 0.6 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region F-box-like_2 PF13013.6 KXG50495.1 - 0.17 11.9 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain AAA_23 PF13476.6 KXG50495.1 - 2.7 8.5 5.8 6 7.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain DnaJ_C PF01556.18 KXG50496.1 - 2.3e-35 121.9 0.0 3.2e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXG50496.1 - 1.4e-22 79.6 5.3 2.6e-22 78.7 5.3 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXG50496.1 - 8.2e-09 35.7 18.4 1.8e-08 34.6 18.4 1.6 1 0 0 1 1 1 1 DnaJ central domain GRP PF07172.11 KXG50496.1 - 0.98 10.2 15.2 4.2 8.1 15.2 2.2 1 0 0 1 1 1 0 Glycine rich protein family BRO1 PF03097.18 KXG50497.1 - 9.7e-119 396.6 3.8 9.7e-119 396.6 3.8 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KXG50497.1 - 1.1e-67 228.5 15.3 1.1e-67 228.5 15.3 2.4 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV FadR_C PF07840.12 KXG50497.1 - 0.11 12.4 1.1 0.36 10.7 1.1 1.8 1 0 0 1 1 1 0 FadR C-terminal domain Fib_alpha PF08702.10 KXG50497.1 - 0.12 12.5 12.0 0.13 12.5 1.8 3.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family FAP206 PF12018.8 KXG50497.1 - 0.53 9.7 6.3 0.043 13.3 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function Sec8_exocyst PF04048.14 KXG50497.1 - 3.3 7.6 6.7 2.5 8.0 1.0 3.3 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain SAP30_Sin3_bdg PF13867.6 KXG50498.1 - 7.5e-09 35.8 0.1 1.4e-07 31.7 0.0 2.4 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 LMBR1 PF04791.16 KXG50498.1 - 0.22 10.4 0.2 0.24 10.3 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-C2H2 PF00096.26 KXG50499.1 - 4.3e-08 33.2 17.1 0.00069 19.9 4.5 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXG50499.1 - 1.9e-07 31.2 21.6 5.2e-05 23.5 3.3 4.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXG50499.1 - 0.0016 19.1 15.8 0.048 14.5 3.0 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 KXG50499.1 - 0.029 15.0 1.7 0.14 12.8 0.2 2.7 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KXG50499.1 - 0.031 14.6 1.4 0.11 12.8 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KXG50499.1 - 0.032 14.5 0.7 0.084 13.2 0.7 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KXG50499.1 - 0.11 12.5 0.8 8.3 6.5 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger LSM PF01423.22 KXG50502.1 - 1.6e-14 53.3 0.1 2.6e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 LSM domain DNA_pol3_chi PF04364.13 KXG50502.1 - 0.069 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC NUC173 PF08161.12 KXG50503.1 - 1.5e-80 269.7 0.0 2.6e-77 259.1 0.0 3.1 3 0 0 3 3 3 2 NUC173 domain CdiI_2 PF18593.1 KXG50503.1 - 0.018 15.7 0.1 7.7 7.3 0.0 3.2 3 0 0 3 3 3 0 CdiI immunity protein HEAT PF02985.22 KXG50503.1 - 0.034 14.4 1.5 16 6.1 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat TFCD_C PF12612.8 KXG50503.1 - 0.39 10.5 1.8 11 5.8 0.0 3.6 4 0 0 4 4 4 0 Tubulin folding cofactor D C terminal TFIIF_alpha PF05793.12 KXG50503.1 - 8.2 4.9 19.8 0.047 12.3 11.3 1.5 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cwf_Cwc_15 PF04889.12 KXG50503.1 - 9.3 5.9 12.7 0.36 10.5 5.8 2.1 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Epimerase PF01370.21 KXG50504.1 - 5.3e-12 45.7 0.0 1.5e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXG50504.1 - 1.1e-11 44.9 0.3 1.9e-11 44.2 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KXG50504.1 - 2.3e-09 37.7 0.1 4e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KXG50504.1 - 2.1e-08 34.0 0.2 3.3e-08 33.4 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KXG50504.1 - 4.6e-05 23.7 0.1 8.2e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KXG50504.1 - 4.9e-05 22.6 0.0 0.00013 21.2 0.1 1.7 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KXG50504.1 - 0.0006 19.0 0.2 0.00094 18.4 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 KXG50504.1 - 0.0031 17.6 0.1 0.0066 16.6 0.1 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 KXG50504.1 - 0.0064 17.2 0.1 0.01 16.5 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase RmlD_sub_bind PF04321.17 KXG50504.1 - 0.0075 15.4 0.3 0.057 12.5 0.2 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain GFO_IDH_MocA PF01408.22 KXG50504.1 - 0.012 16.4 0.2 0.03 15.1 0.2 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 3Beta_HSD PF01073.19 KXG50504.1 - 0.013 14.5 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family UVR PF02151.19 KXG50504.1 - 0.36 10.6 2.4 13 5.7 0.1 2.4 2 0 0 2 2 2 0 UvrB/uvrC motif F-box-like PF12937.7 KXG50505.1 - 0.00032 20.5 0.2 0.00082 19.2 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXG50505.1 - 0.014 15.3 2.6 0.025 14.5 0.9 2.3 2 1 0 2 2 2 0 F-box domain F-box_5 PF18511.1 KXG50505.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 F-box zf-C2H2 PF00096.26 KXG50506.1 - 1.5e-07 31.5 7.2 1.7e-06 28.2 0.2 2.6 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXG50506.1 - 1.2e-06 28.7 5.9 3.5e-05 24.0 0.2 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXG50506.1 - 3.4e-06 27.4 4.4 0.0037 18.0 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger Zap1_zf2 PF18217.1 KXG50506.1 - 0.026 14.5 0.1 0.092 12.8 0.1 2.0 1 1 0 1 1 1 0 Zap1 zinc finger 2 FOXP-CC PF16159.5 KXG50506.1 - 0.059 14.0 1.3 1.5 9.5 0.1 2.2 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KXG50506.1 - 0.15 11.8 11.0 0.34 10.7 0.5 2.9 2 1 0 2 2 2 0 C2H2-type zinc-finger domain MFS_1 PF07690.16 KXG50507.1 - 3.9e-16 58.9 49.0 2e-15 56.6 42.5 3.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG50507.1 - 4.6e-16 58.4 13.2 4.6e-16 58.4 13.2 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TNFR_16_TM PF18422.1 KXG50507.1 - 0.18 11.8 1.8 0.38 10.7 0.2 2.6 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Cpta_toxin PF07254.12 KXG50507.1 - 4.4 7.3 7.9 1.2 9.1 0.5 3.0 3 0 0 3 3 3 0 Membrane-bound toxin component of toxin-antitoxin system p450 PF00067.22 KXG50508.1 - 1.1e-62 212.3 0.0 1.4e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.15 KXG50509.1 - 3.7e-35 121.4 0.0 5.5e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Transferase family Condensation PF00668.20 KXG50509.1 - 0.0004 19.2 0.0 0.00064 18.5 0.0 1.3 1 0 0 1 1 1 1 Condensation domain SnoaL_2 PF12680.7 KXG50509.1 - 0.16 12.6 0.1 0.48 11.1 0.0 1.8 2 0 0 2 2 2 0 SnoaL-like domain DAO PF01266.24 KXG50510.1 - 7.2e-51 173.8 0.1 9.9e-51 173.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glyco_transf_28 PF03033.20 KXG50510.1 - 7.6e-22 77.9 0.0 2e-21 76.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Pyr_redox_3 PF13738.6 KXG50510.1 - 2.4e-05 23.8 0.0 0.00036 19.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG50510.1 - 0.012 15.9 0.1 0.037 14.3 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXG50510.1 - 0.015 14.5 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family ATG_C PF09333.11 KXG50510.1 - 0.018 15.4 0.0 0.16 12.3 0.0 2.5 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain NAD_binding_9 PF13454.6 KXG50510.1 - 0.019 14.9 0.1 0.083 12.9 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding VPS13_C PF16909.5 KXG50510.1 - 0.17 11.6 0.0 0.48 10.2 0.0 1.7 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal 2OG-FeII_Oxy_2 PF13532.6 KXG50511.1 - 1.7e-16 61.0 0.0 2.2e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KXG50511.1 - 0.0063 17.0 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyoxalase PF00903.25 KXG50512.1 - 0.099 12.8 0.0 0.28 11.4 0.0 1.7 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ala_racemase_N PF01168.20 KXG50513.1 - 8.8e-27 94.2 0.0 1.1e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 KXG50513.1 - 8.3e-21 74.5 0.0 2.1e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain SDH_alpha PF03313.15 KXG50513.1 - 0.013 15.2 0.3 0.67 9.6 0.1 2.3 2 0 0 2 2 2 0 Serine dehydratase alpha chain GTP_CH_N PF12471.8 KXG50513.1 - 0.079 12.7 0.0 0.81 9.4 0.0 2.3 3 0 0 3 3 3 0 GTP cyclohydrolase N terminal Glyco_hydro_16 PF00722.21 KXG50514.1 - 3.6e-07 29.8 0.1 7e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fructosamin_kin PF03881.14 KXG50515.1 - 5.1e-40 137.5 0.0 6.7e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KXG50515.1 - 0.0053 16.7 0.0 0.0089 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family NmrA PF05368.13 KXG50517.1 - 8.6e-39 133.5 0.0 1.1e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG50517.1 - 4.9e-12 46.1 0.0 6.4e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXG50517.1 - 8.4e-06 25.0 0.0 1.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXG50517.1 - 0.00011 21.8 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXG50517.1 - 0.0027 16.9 0.0 0.0037 16.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein CoA_transf_3 PF02515.17 KXG50519.1 - 0.1 11.7 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 CoA-transferase family III p450 PF00067.22 KXG50521.1 - 5.6e-70 236.4 0.0 7.8e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF481 PF04338.12 KXG50522.1 - 0.016 15.2 2.0 0.02 14.9 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF481 RNase_T PF00929.24 KXG50524.1 - 2.2e-09 38.1 0.0 4.4e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Exonuclease zf-C2H2_4 PF13894.6 KXG50524.1 - 0.0022 18.7 0.5 5.3 8.2 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger DNA_pol_A_exo1 PF01612.20 KXG50524.1 - 0.0099 15.6 0.0 0.021 14.5 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease zf-C2H2_2 PF12756.7 KXG50524.1 - 0.023 15.0 0.1 0.14 12.5 0.0 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KXG50524.1 - 0.023 15.0 3.1 3.7 7.9 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KXG50524.1 - 0.41 11.3 1.5 0.57 10.9 0.1 2.0 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KXG50524.1 - 0.79 10.2 6.6 3.4 8.2 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ribosomal_L3 PF00297.22 KXG50527.1 - 1.2e-183 610.2 11.1 1.6e-183 609.8 11.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.28 KXG50527.1 - 1.7e-49 163.7 27.3 8.6e-08 31.7 0.1 10.8 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KXG50527.1 - 1.1e-44 147.0 17.0 8.9e-06 25.4 0.0 10.9 11 1 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 KXG50527.1 - 1e-36 122.1 20.1 3.2e-06 26.9 0.0 10.9 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 KXG50527.1 - 7e-25 86.4 21.6 6.4e-05 22.6 1.4 9.7 6 2 3 9 9 9 7 TPR repeat TPR_17 PF13431.6 KXG50527.1 - 3.4e-24 83.4 17.6 4.2e-05 23.6 0.1 9.4 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXG50527.1 - 7.5e-24 82.4 4.6 0.00055 20.5 0.0 8.7 5 2 4 9 9 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 KXG50527.1 - 1.4e-23 83.1 16.8 0.00068 20.1 0.0 8.2 5 3 3 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 KXG50527.1 - 9.2e-23 80.3 15.9 8.3e-05 22.8 0.1 7.9 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXG50527.1 - 6.6e-18 65.1 21.6 8.2e-05 23.2 0.1 8.6 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXG50527.1 - 4.5e-17 61.5 15.0 0.015 15.9 0.0 9.9 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXG50527.1 - 7.3e-17 60.1 12.1 0.048 13.7 0.0 9.4 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXG50527.1 - 7.5e-15 54.8 12.4 0.046 13.9 0.1 7.5 4 2 5 9 9 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG50527.1 - 1.3e-10 41.3 10.6 2.1e-07 31.1 1.4 3.9 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KXG50527.1 - 1.1e-07 31.4 8.8 0.00066 19.0 1.6 4.7 1 1 1 3 3 3 3 Tetratricopeptide repeat BTAD PF03704.17 KXG50527.1 - 1.7e-05 25.3 4.8 0.023 15.1 0.0 3.5 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_21 PF09976.9 KXG50527.1 - 7.6e-05 22.5 6.5 0.064 13.0 0.0 4.4 3 2 1 5 5 4 1 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 KXG50527.1 - 0.00078 19.2 5.6 45 4.1 0.2 7.0 8 1 0 8 8 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KXG50527.1 - 0.0039 16.6 5.0 0.061 12.7 0.0 3.3 2 1 1 3 3 3 1 MalT-like TPR region DUF2225 PF09986.9 KXG50527.1 - 0.0056 16.4 4.6 1.9 8.1 0.0 3.2 3 1 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.10 KXG50527.1 - 0.67 8.9 2.1 11 4.8 0.2 2.6 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 KXG50527.1 - 7.1 7.0 6.9 15 6.0 0.1 3.9 3 1 2 5 5 4 0 Tetratricopeptide repeat NuiA PF07924.11 KXG50528.1 - 0.0086 16.5 0.0 5.4 7.4 0.0 2.2 2 0 0 2 2 2 2 Nuclease A inhibitor-like protein SKN1 PF03935.15 KXG50529.1 - 1.2e-222 739.8 0.2 1.4e-222 739.6 0.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) BCDHK_Adom3 PF10436.9 KXG50531.1 - 1.5e-74 249.2 0.0 2e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXG50531.1 - 8.6e-13 48.8 0.0 1.8e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXG50531.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.17 KXG50531.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Lyase_1 PF00206.20 KXG50532.1 - 1.6e-21 77.0 0.0 3.9e-21 75.8 0.0 1.6 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.9 KXG50532.1 - 2.8e-16 59.8 0.4 1.4e-15 57.6 0.0 2.3 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Exo70 PF03081.15 KXG50533.1 - 1.5e-83 280.9 0.0 3.3e-83 279.8 0.0 1.5 2 0 0 2 2 2 1 Exo70 exocyst complex subunit NPV_P10 PF05531.12 KXG50533.1 - 0.012 16.1 2.6 0.31 11.5 0.0 3.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PLA2_B PF01735.18 KXG50534.1 - 2.8e-28 98.6 0.0 8.8e-28 97.0 0.0 1.7 1 1 0 1 1 1 1 Lysophospholipase catalytic domain DSPc PF00782.20 KXG50535.1 - 3.3e-10 39.9 0.0 5.7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXG50535.1 - 1.4e-06 28.1 0.0 2.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KXG50535.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KXG50535.1 - 0.098 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate PPR_3 PF13812.6 KXG50537.1 - 3.2e-12 46.3 0.6 2.7e-05 24.2 0.0 6.0 4 2 3 7 7 7 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 KXG50537.1 - 3e-11 43.3 0.8 0.00018 21.7 0.1 7.1 6 3 2 8 8 8 2 PPR repeat family PPR PF01535.20 KXG50537.1 - 7.7e-08 32.1 8.2 5.6 7.4 0.1 7.8 8 0 0 8 8 8 3 PPR repeat PPR_long PF17177.4 KXG50537.1 - 3.7e-07 29.7 0.1 0.028 13.8 0.0 2.9 1 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KXG50537.1 - 0.0012 18.4 0.0 11 5.8 0.0 4.7 5 0 0 5 5 5 1 PPR repeat DUF1415 PF07209.12 KXG50537.1 - 0.051 13.3 0.0 0.19 11.4 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1415) LSM PF01423.22 KXG50538.1 - 5.9e-19 67.5 0.0 8.4e-19 67.0 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXG50538.1 - 0.0031 17.6 0.0 0.004 17.3 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain ABM PF03992.16 KXG50539.1 - 0.0049 16.9 0.1 0.0081 16.3 0.1 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Hat1_N PF10394.9 KXG50540.1 - 7.2e-52 175.9 0.0 1.3e-51 175.0 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Alginate_lyase PF05426.12 KXG50541.1 - 5.8e-14 52.3 1.8 1.3e-13 51.1 1.8 1.6 1 0 0 1 1 1 1 Alginate lyase Fungal_trans_2 PF11951.8 KXG50541.1 - 7.4e-06 25.0 0.1 1.5e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG50541.1 - 0.11 12.7 4.2 0.19 11.9 4.2 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Chorion_1 PF01723.16 KXG50541.1 - 0.17 11.9 2.6 0.34 10.8 2.6 1.4 1 0 0 1 1 1 0 Chorion protein Zip PF02535.22 KXG50542.1 - 7.9e-35 120.6 17.6 1.1e-31 110.3 17.6 3.0 1 1 0 1 1 1 1 ZIP Zinc transporter WD40 PF00400.32 KXG50543.1 - 5.1e-39 131.6 20.6 2.5e-07 31.3 0.1 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 KXG50543.1 - 6.6e-11 41.9 0.4 1.4e-10 40.9 0.4 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KXG50543.1 - 1.5e-08 34.8 0.7 0.38 11.1 0.0 6.1 1 1 5 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXG50543.1 - 5.6e-07 28.6 7.4 0.034 12.8 0.1 5.4 2 1 4 6 6 6 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KXG50543.1 - 8.3e-05 22.0 0.0 0.014 14.7 0.0 2.7 1 1 2 3 3 3 2 WD40-like domain F-box PF00646.33 KXG50543.1 - 0.00016 21.5 0.4 0.00042 20.1 0.4 1.8 1 0 0 1 1 1 1 F-box domain PALB2_WD40 PF16756.5 KXG50543.1 - 0.00067 18.7 3.4 0.7 8.8 0.0 3.9 2 1 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 KXG50543.1 - 0.028 14.0 3.1 0.15 11.6 1.0 2.8 1 1 1 2 2 2 0 PQQ-like domain F-box_5 PF18511.1 KXG50543.1 - 0.044 13.3 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 F-box Fungal_trans_2 PF11951.8 KXG50544.1 - 1.3e-05 24.2 0.7 1.3e-05 24.2 0.7 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3716 PF12511.8 KXG50545.1 - 9.9e-10 38.3 9.0 1.5e-09 37.8 9.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Mito_carr PF00153.27 KXG50546.1 - 1.2e-46 156.5 5.8 3.1e-16 59.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF155 PF02582.14 KXG50548.1 - 4.2e-52 176.8 0.0 7.3e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 U3_snoRNA_assoc PF08297.11 KXG50549.1 - 2.3e-16 60.2 1.6 2.3e-16 60.2 1.6 3.8 2 1 1 3 3 3 1 U3 snoRNA associated RRP14 PF15459.6 KXG50549.1 - 1 10.0 18.4 0.97 10.1 9.4 2.9 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 CTK3 PF12243.8 KXG50550.1 - 1.7e-51 173.3 0.2 3.4e-51 172.4 0.2 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KXG50550.1 - 4.6e-17 61.9 7.9 4.6e-17 61.9 7.9 1.9 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus DUF3873 PF12989.7 KXG50550.1 - 0.064 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) Voltage_CLC PF00654.20 KXG50551.1 - 1.4e-89 300.8 26.6 1.4e-89 300.8 26.6 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KXG50551.1 - 9.6e-05 22.8 0.0 0.14 12.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain Comm PF15957.5 KXG50551.1 - 0.22 11.9 0.3 1.5 9.2 0.3 2.3 2 0 0 2 2 2 0 Commissureless AAA_5 PF07728.14 KXG50552.1 - 6.1e-129 424.7 0.2 7e-22 77.9 0.0 9.7 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KXG50552.1 - 1e-49 167.2 6.6 5.7e-18 65.1 0.0 5.6 5 0 0 5 5 4 4 Midasin AAA lid domain AAA_7 PF12775.7 KXG50552.1 - 1.5e-30 106.1 1.7 9.5e-06 25.2 0.0 7.3 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA_lid_5 PF17865.1 KXG50552.1 - 3.2e-30 104.3 0.6 3.9e-28 97.6 0.0 3.1 3 0 0 3 3 2 1 Midasin AAA lid domain AAA_3 PF07726.11 KXG50552.1 - 1.1e-29 102.9 0.0 8.8e-11 41.8 0.0 7.4 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KXG50552.1 - 2e-28 99.4 0.0 0.00028 21.3 0.0 7.1 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXG50552.1 - 7.8e-25 88.2 15.2 4.5e-05 23.9 0.2 8.8 7 1 0 7 7 6 5 AAA ATPase domain Dynein_heavy PF03028.15 KXG50552.1 - 6.2e-23 81.1 0.0 3.8e-06 27.0 0.0 7.8 8 0 0 8 8 7 4 Dynein heavy chain region D6 P-loop domain AAA_33 PF13671.6 KXG50552.1 - 2.1e-19 70.1 0.0 0.0018 18.5 0.0 7.0 6 0 0 6 6 6 3 AAA domain AAA_30 PF13604.6 KXG50552.1 - 1.7e-18 67.0 0.0 0.0047 16.7 0.0 7.4 6 2 0 6 6 6 4 AAA domain AAA_22 PF13401.6 KXG50552.1 - 5.2e-18 65.6 0.4 0.063 13.6 0.0 8.0 7 0 0 7 7 6 4 AAA domain AAA_18 PF13238.6 KXG50552.1 - 2.7e-17 63.5 0.3 0.034 14.7 0.0 7.3 6 0 0 6 6 6 3 AAA domain AAA_14 PF13173.6 KXG50552.1 - 7.2e-17 61.7 0.0 0.013 15.6 0.0 7.2 7 0 0 7 7 6 3 AAA domain TsaE PF02367.17 KXG50552.1 - 3.2e-16 59.5 2.5 0.16 12.0 0.1 6.8 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_6 PF12774.7 KXG50552.1 - 1e-15 57.5 0.0 0.075 12.0 0.0 8.4 9 0 0 9 9 8 3 Hydrolytic ATP binding site of dynein motor region ABC_tran PF00005.27 KXG50552.1 - 1.7e-15 57.7 0.5 0.0097 16.4 0.0 7.0 6 0 0 6 6 6 3 ABC transporter Sigma54_activat PF00158.26 KXG50552.1 - 1.9e-14 53.7 0.0 0.011 15.5 0.0 6.0 6 0 0 6 6 6 3 Sigma-54 interaction domain Zeta_toxin PF06414.12 KXG50552.1 - 3.5e-13 49.3 2.0 0.8 9.0 0.0 7.6 7 0 0 7 7 7 3 Zeta toxin RNA_helicase PF00910.22 KXG50552.1 - 8.8e-13 48.6 0.9 0.91 9.9 0.0 6.8 6 0 0 6 6 6 3 RNA helicase Mg_chelatase PF01078.21 KXG50552.1 - 1.2e-12 47.7 0.3 2 7.8 0.0 8.7 9 0 0 9 9 9 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KXG50552.1 - 3.2e-12 46.7 8.5 0.076 12.9 0.1 6.4 6 0 0 6 6 6 4 NACHT domain SRP54 PF00448.22 KXG50552.1 - 2.1e-11 43.8 3.2 0.073 12.7 0.0 6.1 6 0 0 6 6 6 2 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 KXG50552.1 - 4.1e-11 43.1 4.3 0.083 12.8 0.1 6.3 6 0 0 6 6 6 2 RsgA GTPase RuvB_N PF05496.12 KXG50552.1 - 5.9e-11 42.4 6.9 0.32 10.7 0.0 7.1 7 0 0 7 7 7 3 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KXG50552.1 - 2.7e-10 40.7 3.3 0.51 10.7 0.0 6.8 6 1 0 6 6 5 1 AAA domain AAA_28 PF13521.6 KXG50552.1 - 3.8e-10 40.3 4.5 0.25 11.6 0.1 6.8 6 0 0 6 6 6 2 AAA domain MMR_HSR1 PF01926.23 KXG50552.1 - 2.3e-09 37.3 1.8 0.039 14.0 0.0 6.6 6 0 0 6 6 6 1 50S ribosome-binding GTPase Sigma54_activ_2 PF14532.6 KXG50552.1 - 3.4e-09 36.9 0.3 0.11 12.6 0.1 5.4 5 0 0 5 5 5 2 Sigma-54 interaction domain ATPase_2 PF01637.18 KXG50552.1 - 3.9e-09 36.8 0.0 1.9 8.3 0.0 6.1 6 0 0 6 6 6 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 KXG50552.1 - 8.4e-09 35.6 0.3 0.27 11.2 0.0 5.5 5 0 0 5 5 5 1 Rad17 P-loop domain PduV-EutP PF10662.9 KXG50552.1 - 1.3e-08 34.7 4.2 0.12 12.1 0.0 6.0 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 KXG50552.1 - 2.1e-08 34.0 5.8 2.3 7.7 0.0 6.4 7 0 0 7 7 5 2 AAA domain IstB_IS21 PF01695.17 KXG50552.1 - 2.2e-08 34.0 0.1 1 9.0 0.0 5.7 5 0 0 5 5 5 2 IstB-like ATP binding protein Roc PF08477.13 KXG50552.1 - 7.8e-08 32.6 1.5 11 6.3 0.0 6.3 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KXG50552.1 - 8.1e-08 31.7 2.0 0.6 9.2 0.1 5.5 6 0 0 6 6 6 2 Protein of unknown function (DUF815) AAA_29 PF13555.6 KXG50552.1 - 9.5e-08 31.7 2.2 1.6 8.6 0.0 6.3 6 0 0 6 6 6 1 P-loop containing region of AAA domain T2SSE PF00437.20 KXG50552.1 - 1.4e-07 30.9 2.4 0.25 10.4 0.0 6.0 6 0 0 6 6 6 1 Type II/IV secretion system protein TniB PF05621.11 KXG50552.1 - 3.3e-07 29.9 0.1 1.7 8.0 0.0 5.8 6 0 0 6 6 5 1 Bacterial TniB protein AAA_24 PF13479.6 KXG50552.1 - 4.7e-07 29.7 0.5 3.9 7.1 0.0 6.5 7 0 0 7 7 6 0 AAA domain MCM PF00493.23 KXG50552.1 - 6.1e-07 28.8 0.1 1.2 8.2 0.0 5.0 5 0 0 5 5 5 1 MCM P-loop domain Viral_helicase1 PF01443.18 KXG50552.1 - 7.7e-07 29.1 0.1 0.32 10.7 0.0 5.2 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KXG50552.1 - 2.8e-06 27.3 5.4 2.5 8.0 0.1 5.5 5 0 0 5 5 5 1 NTPase ATP_bind_1 PF03029.17 KXG50552.1 - 5.5e-06 26.3 3.1 3.4 7.4 0.1 6.0 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein AAA_9 PF12781.7 KXG50552.1 - 6.6e-06 25.4 0.0 0.037 13.2 0.0 4.6 6 0 0 6 6 5 1 ATP-binding dynein motor region SRPRB PF09439.10 KXG50552.1 - 1.2e-05 24.8 3.1 2.3 7.6 0.0 6.1 6 0 0 6 6 6 1 Signal recognition particle receptor beta subunit Bac_DnaA PF00308.18 KXG50552.1 - 2.1e-05 24.4 0.3 1.5 8.6 0.0 4.2 5 0 0 5 5 3 1 Bacterial dnaA protein TIP49 PF06068.13 KXG50552.1 - 5.9e-05 22.4 1.1 0.6 9.2 0.0 4.9 6 0 0 6 6 5 1 TIP49 P-loop domain ResIII PF04851.15 KXG50552.1 - 6.5e-05 23.0 0.1 2 8.4 0.0 4.7 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit cobW PF02492.19 KXG50552.1 - 7.3e-05 22.4 6.5 3.3 7.3 0.1 6.1 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 KXG50552.1 - 0.00026 21.0 0.0 0.71 9.9 0.0 4.0 4 0 0 4 4 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain PhoH PF02562.16 KXG50552.1 - 0.00039 19.9 0.6 1.6 8.1 0.0 4.5 5 0 0 5 5 4 1 PhoH-like protein NB-ARC PF00931.22 KXG50552.1 - 0.00076 18.7 2.6 8.5 5.5 0.0 5.4 6 0 0 6 6 5 0 NB-ARC domain FeoB_N PF02421.18 KXG50552.1 - 0.0029 17.1 5.1 0.65 9.5 0.0 5.1 6 0 0 6 6 5 1 Ferrous iron transport protein B DnaB_C PF03796.15 KXG50552.1 - 0.003 16.9 4.6 2.4 7.4 0.0 4.6 4 0 0 4 4 4 1 DnaB-like helicase C terminal domain ATPase PF06745.13 KXG50552.1 - 0.0036 16.7 1.0 29 3.9 0.0 5.0 5 0 0 5 5 5 0 KaiC CPT PF07931.12 KXG50552.1 - 0.0039 17.1 0.2 3.8 7.3 0.0 5.0 5 1 0 5 5 3 0 Chloramphenicol phosphotransferase-like protein MobB PF03205.14 KXG50552.1 - 0.0093 15.9 7.4 44 4.0 0.0 5.9 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.10 KXG50552.1 - 0.01 15.3 0.1 3.5 7.0 0.0 4.0 3 0 0 3 3 3 0 Chromatin associated protein KTI12 dNK PF01712.19 KXG50552.1 - 0.045 13.6 2.0 15 5.3 0.0 4.3 4 0 0 4 4 3 0 Deoxynucleoside kinase SUD-M PF11633.8 KXG50552.1 - 0.045 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain DEAD PF00270.29 KXG50552.1 - 0.084 12.6 0.4 20 4.9 0.0 3.6 4 0 0 4 4 3 0 DEAD/DEAH box helicase Septin PF00735.18 KXG50552.1 - 0.12 11.7 2.2 7.3 5.8 0.0 4.1 6 0 0 6 6 5 0 Septin MeaB PF03308.16 KXG50552.1 - 0.34 9.8 4.9 5.2 6.0 0.2 3.2 4 0 0 4 4 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 KXG50552.1 - 0.35 10.3 1.8 14 5.1 0.1 4.1 6 0 0 6 6 4 0 ADP-ribosylation factor family FAA_hydro_N_2 PF18288.1 KXG50552.1 - 5.6 7.5 7.4 19 5.7 0.0 4.6 4 0 0 4 4 3 0 Fumarylacetoacetase N-terminal domain 2 PRCC PF10253.9 KXG50553.1 - 6.5e-30 105.5 23.9 6.5e-30 105.5 23.9 3.0 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Pkinase PF00069.25 KXG50554.1 - 2.8e-71 240.0 0.0 3.4e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG50554.1 - 2.2e-37 128.8 0.0 2.9e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG50554.1 - 1.6e-06 27.7 0.0 3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXG50554.1 - 0.02 14.8 0.2 0.054 13.4 0.0 1.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family dbPDZ_assoc PF16610.5 KXG50554.1 - 0.1 12.8 1.6 0.18 12.0 1.6 1.3 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 zf-Tim10_DDP PF02953.15 KXG50555.1 - 1.6e-21 75.7 0.6 2e-21 75.4 0.6 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Lectin_leg-like PF03388.13 KXG50556.1 - 1.6e-63 214.1 0.0 2.1e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family PBP1_TM PF14812.6 KXG50556.1 - 0.038 14.3 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BRF1 PF07741.13 KXG50557.1 - 6.2 7.2 14.9 7.5 7.0 6.5 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain RFC1 PF08519.12 KXG50558.1 - 1.4e-57 194.3 0.0 4e-57 192.8 0.0 1.9 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain CRIM PF16978.5 KXG50558.1 - 1.7e-40 138.4 0.0 4.9e-40 136.9 0.0 1.8 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KXG50558.1 - 4.1e-25 88.2 0.1 1.5e-24 86.4 0.1 2.1 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology BRCT PF00533.26 KXG50558.1 - 1.4e-13 51.0 0.0 3.6e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KXG50558.1 - 1.4e-09 38.5 0.4 7.5e-09 36.1 0.1 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXG50558.1 - 6.9e-06 26.1 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KXG50558.1 - 0.00015 22.0 0.0 0.001 19.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain DTHCT PF08070.11 KXG50558.1 - 0.0022 18.7 7.0 0.0022 18.7 7.0 8.3 6 2 2 8 8 5 1 DTHCT (NUC029) region AAA_33 PF13671.6 KXG50558.1 - 0.0027 17.8 1.5 0.01 16.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KXG50558.1 - 0.0056 16.7 0.0 0.02 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXG50558.1 - 0.0064 16.9 0.1 0.026 14.9 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXG50558.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KXG50558.1 - 0.012 15.3 1.5 0.02 14.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXG50558.1 - 0.021 15.4 0.5 0.13 12.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KXG50558.1 - 0.037 14.0 0.0 0.092 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ribosomal_L16 PF00252.18 KXG50559.1 - 1.2e-31 109.4 0.1 1.5e-31 109.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DNA_pol3_delta2 PF13177.6 KXG50561.1 - 2.8e-10 40.2 0.0 6.3e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KXG50561.1 - 3e-06 27.7 0.0 7.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXG50561.1 - 4.3e-05 23.8 0.4 0.0002 21.6 0.1 2.2 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXG50561.1 - 0.0011 19.4 0.9 0.0077 16.6 0.4 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KXG50561.1 - 0.0054 16.5 0.2 0.014 15.1 0.2 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KXG50561.1 - 0.018 15.0 0.0 0.062 13.2 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain Rep_fac_C PF08542.11 KXG50561.1 - 0.034 14.5 0.0 0.094 13.1 0.0 1.8 1 0 0 1 1 1 0 Replication factor C C-terminal domain ABC_tran PF00005.27 KXG50561.1 - 0.067 13.7 0.0 0.1 13.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.14 KXG50561.1 - 0.074 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer CtaG_Cox11 PF04442.14 KXG50562.1 - 3.4e-60 202.4 0.0 4.5e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 TMEM135_C_rich PF15982.5 KXG50563.1 - 0.00044 20.9 1.8 0.0017 18.9 1.1 2.4 2 1 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 HLH PF00010.26 KXG50564.1 - 1.1e-06 28.5 0.0 3.5e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CENP-Q PF13094.6 KXG50565.1 - 4.3e-50 170.2 7.3 6.1e-50 169.7 7.3 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit HAP1_N PF04849.13 KXG50565.1 - 0.0015 17.8 5.2 0.0022 17.3 5.2 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Golgin_A5 PF09787.9 KXG50565.1 - 0.028 13.9 3.5 0.045 13.2 3.5 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF5622 PF18533.1 KXG50565.1 - 0.13 12.4 0.6 0.29 11.3 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5622) PRKG1_interact PF15898.5 KXG50565.1 - 0.13 13.1 7.5 0.1 13.5 4.7 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain SlyX PF04102.12 KXG50565.1 - 0.93 10.2 4.9 2.7 8.7 3.3 2.4 2 0 0 2 2 2 0 SlyX DUF1843 PF08898.10 KXG50565.1 - 5.6 7.5 7.9 3.6 8.2 0.9 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF1843) SPO22 PF08631.10 KXG50567.1 - 2.5e-17 63.3 0.0 4.5e-16 59.1 0.0 2.7 2 1 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like NAD_binding_1 PF00175.21 KXG50568.1 - 1.3e-32 112.6 0.0 2.5e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXG50568.1 - 1e-27 96.4 0.0 5.2e-27 94.1 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KXG50568.1 - 2.3e-22 78.9 0.1 4e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KXG50568.1 - 2.5e-06 27.7 0.0 0.0005 20.2 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KXG50568.1 - 0.0031 17.7 0.0 0.042 14.1 0.0 2.3 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain MDMPI_N PF11716.8 KXG50568.1 - 0.047 14.4 0.2 0.098 13.3 0.2 1.6 1 1 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain GreA_GreB PF01272.19 KXG50568.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Transcription elongation factor, GreA/GreB, C-term p450 PF00067.22 KXG50569.1 - 8e-74 249.0 0.0 9.4e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KXG50570.1 - 1.2e-27 96.8 33.1 2.2e-14 53.2 9.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG50570.1 - 0.00014 20.9 19.5 0.0065 15.4 5.1 2.1 1 1 1 2 2 2 2 MFS_1 like family Herpes_UL49_2 PF04823.12 KXG50571.1 - 0.021 14.9 0.0 0.094 12.8 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL49 tegument protein APH PF01636.23 KXG50572.1 - 2.2e-08 34.4 0.1 0.00022 21.3 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG50572.1 - 0.012 15.2 0.0 0.064 12.8 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF5582 PF17819.1 KXG50572.1 - 0.15 12.5 0.3 0.28 11.6 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5582) Aegerolysin PF06355.13 KXG50573.1 - 8.3e-39 132.7 0.3 9.7e-39 132.5 0.3 1.0 1 0 0 1 1 1 1 Aegerolysin DPM3 PF08285.11 KXG50574.1 - 0.11 12.7 2.2 0.21 11.8 0.2 2.4 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) FSH1 PF03959.13 KXG50575.1 - 4.4e-22 78.8 0.0 9.2e-22 77.7 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF1560 PF07597.11 KXG50575.1 - 0.049 13.7 0.0 0.71 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1560) DUF4786 PF16027.5 KXG50575.1 - 0.1 13.2 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4786) ketoacyl-synt PF00109.26 KXG50576.1 - 4.7e-69 232.8 0.1 7.4e-69 232.1 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXG50576.1 - 1.5e-59 200.9 0.1 3.7e-59 199.6 0.1 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KXG50576.1 - 1.4e-53 182.1 0.0 2.2e-53 181.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXG50576.1 - 2.7e-40 138.8 0.2 1e-39 136.9 0.0 2.1 2 1 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXG50576.1 - 3.6e-37 127.0 0.0 8.8e-37 125.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.26 KXG50576.1 - 1.2e-16 60.9 0.2 9.2e-16 58.0 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG50576.1 - 9.6e-15 55.8 0.0 2.3e-13 51.3 0.0 3.3 3 1 1 4 4 3 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KXG50576.1 - 1.3e-13 51.4 0.1 1.1e-11 45.2 0.1 2.7 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KXG50576.1 - 1.7e-13 51.1 0.0 6.4e-13 49.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG50576.1 - 3.4e-09 37.3 0.0 1.4e-08 35.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG50576.1 - 9.4e-09 35.8 0.0 4.2e-08 33.7 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 KXG50576.1 - 3e-08 33.4 1.7 3e-06 26.8 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KXG50576.1 - 2.4e-07 30.7 0.0 7.2e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KXG50576.1 - 1.6e-06 28.4 0.1 4e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 KXG50576.1 - 1.3e-05 25.0 0.0 3.7e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KXG50576.1 - 0.00028 20.3 0.0 0.0006 19.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 KXG50576.1 - 0.00059 19.6 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase DUF938 PF06080.12 KXG50576.1 - 0.00086 19.1 0.0 0.0028 17.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF938) ADH_N PF08240.12 KXG50576.1 - 0.0011 18.8 0.0 0.0036 17.2 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DREV PF05219.12 KXG50576.1 - 0.0073 15.4 0.0 0.02 14.0 0.0 1.7 1 0 0 1 1 1 1 DREV methyltransferase adh_short_C2 PF13561.6 KXG50576.1 - 0.023 14.3 0.2 0.25 10.9 0.0 2.5 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase SPRY PF00622.28 KXG50577.1 - 9.4e-19 67.7 0.0 1.7e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Rax2 PF12768.7 KXG50577.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity PDEase_II PF02112.15 KXG50578.1 - 1.1e-52 179.2 0.0 4e-26 91.9 0.0 3.1 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 KXG50578.1 - 0.00085 19.4 0.1 0.0018 18.3 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXG50578.1 - 0.0033 16.9 0.0 0.0064 16.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Terpene_synth_C PF03936.16 KXG50579.1 - 2.2e-06 27.2 0.2 4e-06 26.4 0.1 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain YjfB_motility PF14070.6 KXG50579.1 - 0.58 10.3 3.5 1.8 8.7 0.1 2.4 2 0 0 2 2 2 0 Putative motility protein Amidase PF01425.21 KXG50580.1 - 6.5e-82 275.9 0.0 1.2e-81 275.0 0.0 1.4 1 0 0 1 1 1 1 Amidase GWT1 PF06423.12 KXG50580.1 - 6.2e-42 143.2 1.9 1.5e-39 135.5 1.6 2.5 2 0 0 2 2 2 2 GWT1 DUF4818 PF16089.5 KXG50580.1 - 0.066 13.7 0.0 0.27 11.7 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4818) DEAD PF00270.29 KXG50581.1 - 3.5e-39 134.4 0.0 5.2e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG50581.1 - 3.9e-23 81.9 0.0 3e-22 79.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXG50581.1 - 6.2e-05 22.3 0.0 9.1e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KXG50581.1 - 0.00043 20.3 0.0 0.00074 19.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXG50581.1 - 0.0012 19.2 0.0 0.0026 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KXG50581.1 - 0.088 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KXG50581.1 - 0.096 12.5 0.0 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 Helicase bZIP_1 PF00170.21 KXG50582.1 - 3.5e-06 27.0 8.1 6e-06 26.3 6.0 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KXG50582.1 - 0.0013 18.8 13.2 0.015 15.3 8.3 2.3 1 1 1 2 2 2 1 Basic region leucine zipper FlxA PF14282.6 KXG50582.1 - 0.005 16.8 4.4 0.011 15.7 4.4 1.6 1 0 0 1 1 1 1 FlxA-like protein Lzipper-MIP1 PF14389.6 KXG50582.1 - 0.0063 16.8 2.5 1.5 9.1 0.1 2.5 1 1 1 2 2 2 2 Leucine-zipper of ternary complex factor MIP1 Not3 PF04065.15 KXG50582.1 - 0.031 13.7 3.3 0.05 13.0 3.3 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Spc7 PF08317.11 KXG50582.1 - 0.082 11.8 5.9 0.11 11.3 5.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 KXG50582.1 - 0.083 13.1 6.7 0.12 12.6 6.7 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 YabA PF06156.13 KXG50582.1 - 0.097 13.3 1.0 0.15 12.7 1.0 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Ribosomal_S20p PF01649.18 KXG50582.1 - 0.1 13.3 2.6 0.15 12.7 2.6 1.2 1 0 0 1 1 1 0 Ribosomal protein S20 DUF4618 PF15397.6 KXG50582.1 - 0.1 12.0 5.4 0.13 11.6 5.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) APG6_N PF17675.1 KXG50582.1 - 0.1 13.1 4.4 0.17 12.4 4.4 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region ABC_tran_CTD PF16326.5 KXG50582.1 - 0.13 12.5 4.8 0.24 11.7 4.8 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain BLOC1_2 PF10046.9 KXG50582.1 - 0.14 12.5 1.9 0.23 11.8 1.9 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.15 KXG50582.1 - 0.19 11.5 4.7 2.3 8.0 2.7 2.4 1 1 1 2 2 2 0 Septum formation initiator LPP PF04728.13 KXG50582.1 - 0.26 11.7 2.6 4.2 7.8 0.2 3.0 2 1 1 3 3 3 0 Lipoprotein leucine-zipper VSG_B PF13206.6 KXG50582.1 - 0.37 10.0 1.4 0.47 9.7 1.4 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain Csm1_N PF18504.1 KXG50582.1 - 0.42 11.0 5.0 1.8 9.0 1.7 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain V_ATPase_I PF01496.19 KXG50582.1 - 0.46 8.3 1.7 0.55 8.1 1.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.8 KXG50582.1 - 0.76 9.9 9.5 1.2 9.3 9.5 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 KXG50582.1 - 0.94 10.1 6.7 7.8 7.2 6.7 2.6 1 1 0 1 1 1 0 SlyX Acyl-CoA_dh_1 PF00441.24 KXG50583.1 - 9.7e-39 133.0 7.3 1.6e-38 132.3 7.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXG50583.1 - 7.5e-28 97.5 1.9 1.3e-27 96.7 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXG50583.1 - 4.7e-25 87.6 0.0 9.7e-25 86.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXG50583.1 - 3e-16 59.9 4.1 5.1e-16 59.2 4.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KXG50583.1 - 0.006 16.3 0.0 0.014 15.1 0.0 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Spore_YtrH PF14034.6 KXG50584.1 - 0.97 9.6 5.2 6.6 7.0 0.0 3.1 3 0 0 3 3 3 0 Sporulation protein YtrH MFS_1 PF07690.16 KXG50585.1 - 5.5e-29 101.2 28.8 5.5e-29 101.2 28.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG50585.1 - 1.9e-09 36.9 13.4 1.9e-09 36.9 13.4 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter FAD_binding_3 PF01494.19 KXG50586.1 - 9.1e-75 252.1 0.0 1.3e-74 251.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXG50586.1 - 0.00033 21.1 0.0 0.041 14.4 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG50586.1 - 0.00045 19.6 0.6 0.012 14.9 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG50586.1 - 0.00064 19.0 0.0 0.008 15.4 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG50586.1 - 0.002 18.3 0.0 0.0078 16.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXG50586.1 - 0.0044 16.1 0.1 2.1 7.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KXG50586.1 - 0.014 14.7 0.0 0.047 13.0 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KXG50586.1 - 0.05 12.3 0.0 0.1 11.3 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein MCD_N PF17408.2 KXG50586.1 - 0.06 13.5 0.1 10 6.4 0.0 2.6 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain DUF3347 PF11827.8 KXG50586.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) DAO PF01266.24 KXG50586.1 - 0.15 11.6 0.0 0.36 10.4 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans PF04082.18 KXG50587.1 - 7.9e-17 61.2 0.0 1.1e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SIMPL PF04402.14 KXG50588.1 - 1.4e-29 104.0 0.0 1.5e-29 103.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Abhydrolase_6 PF12697.7 KXG50590.1 - 5.5e-21 76.2 0.1 6.3e-21 76.0 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG50590.1 - 0.00051 19.4 0.1 0.0044 16.3 0.1 2.2 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KXG50590.1 - 0.018 14.6 0.0 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family LrgB PF04172.16 KXG50591.1 - 0.013 15.1 2.1 0.013 15.1 2.1 1.7 2 0 0 2 2 2 0 LrgB-like family DUF2062 PF09835.9 KXG50591.1 - 2.7 7.8 9.2 0.16 11.8 1.5 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) Ldh_2 PF02615.14 KXG50592.1 - 2.8e-124 414.6 0.3 3.1e-124 414.5 0.3 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Pkinase PF00069.25 KXG50593.1 - 4e-63 213.3 0.0 6.7e-63 212.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG50593.1 - 1.2e-35 123.1 0.0 3.8e-30 105.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXG50593.1 - 3.3e-06 26.6 0.0 0.0044 16.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KXG50593.1 - 0.00047 20.2 0.0 0.0015 18.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXG50593.1 - 0.0012 18.5 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KXG50593.1 - 0.019 14.3 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXG50593.1 - 0.029 13.3 0.1 0.046 12.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Senescence PF06911.12 KXG50594.1 - 2.7e-54 184.3 5.5 4.4e-54 183.6 5.5 1.4 1 0 0 1 1 1 1 Senescence-associated protein DUF3082 PF11282.8 KXG50594.1 - 0.0057 16.9 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3082) Metallophos PF00149.28 KXG50595.1 - 2e-09 38.2 0.9 2.8e-09 37.8 0.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Dus PF01207.17 KXG50596.1 - 6.9e-40 137.1 0.0 5.3e-28 98.0 0.0 2.8 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 KXG50596.1 - 0.00045 19.9 0.5 0.00045 19.9 0.5 2.7 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 KXG50596.1 - 0.13 12.2 0.1 0.98 9.4 0.1 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KXG50596.1 - 1.1 9.9 9.2 1 10.1 3.0 2.5 1 1 1 2 2 2 0 Torus domain zf_CCCH_4 PF18345.1 KXG50596.1 - 1.6 8.9 11.5 0.16 12.1 0.5 2.9 3 0 0 3 3 3 0 Zinc finger domain Peptidase_M24 PF00557.24 KXG50597.1 - 2.3e-21 76.4 0.0 2.8e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Bap31 PF05529.12 KXG50598.1 - 5.1e-50 168.8 5.3 6.3e-50 168.5 5.3 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KXG50598.1 - 3.3e-14 52.6 3.4 6e-14 51.8 3.4 1.5 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain FlxA PF14282.6 KXG50598.1 - 0.11 12.4 0.7 0.18 11.8 0.7 1.3 1 0 0 1 1 1 0 FlxA-like protein MMM1 PF10296.9 KXG50599.1 - 5.4e-06 25.7 0.0 1.2e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 zf-C2H2 PF00096.26 KXG50601.1 - 2.4e-05 24.6 10.2 0.072 13.6 1.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KXG50601.1 - 3.7e-05 24.0 0.6 0.025 14.7 0.0 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KXG50601.1 - 0.00014 22.4 11.8 0.031 15.1 1.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXG50601.1 - 0.013 15.7 1.0 1.2 9.5 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KXG50601.1 - 0.02 15.3 0.5 0.02 15.3 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger double domain TFIIA PF03153.13 KXG50602.1 - 2.5e-79 268.3 6.9 4.1e-79 267.5 6.9 1.3 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Unstab_antitox PF09720.10 KXG50602.1 - 0.23 11.5 2.6 1.5 9.0 1.8 2.4 1 1 1 2 2 2 0 Putative addiction module component ANAPC4_WD40 PF12894.7 KXG50603.1 - 2.2e-15 56.7 5.8 5.2e-06 26.7 0.2 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXG50603.1 - 1e-14 54.7 18.9 0.00038 21.2 0.1 6.9 6 1 1 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXG50603.1 - 1.2e-05 24.4 0.1 0.0014 17.6 0.0 3.1 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXG50603.1 - 0.00047 20.1 2.5 0.0098 15.8 0.2 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Kelch_4 PF13418.6 KXG50604.1 - 6.5e-26 90.1 9.9 1.4e-07 31.3 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KXG50604.1 - 2.8e-23 81.4 0.1 0.00022 21.2 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 KXG50604.1 - 8.6e-20 70.3 1.0 6.1e-05 23.2 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KXG50604.1 - 2.6e-19 69.0 7.6 9.8e-08 32.1 0.0 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KXG50604.1 - 6.2e-19 67.2 0.7 7.2e-06 25.8 0.1 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 KXG50604.1 - 2.4e-17 62.2 0.0 7.6e-05 22.2 0.1 4.9 5 0 0 5 5 5 4 Kelch motif BTB PF00651.31 KXG50604.1 - 4.5e-10 39.7 0.0 7.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain bPH_6 PF10756.9 KXG50604.1 - 0.048 13.8 0.0 0.18 11.9 0.0 2.1 1 0 0 1 1 1 0 Bacterial PH domain BACK PF07707.15 KXG50604.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch Glyco_hydro_1 PF00232.18 KXG50605.1 - 6.7e-155 515.9 0.0 8.4e-155 515.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 CUE PF02845.16 KXG50605.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 CUE domain MFS_1 PF07690.16 KXG50606.1 - 3.1e-31 108.6 31.4 3.1e-31 108.6 31.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXG50606.1 - 2.6e-05 23.7 8.9 2.6e-05 23.7 8.9 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Amidase PF01425.21 KXG50607.1 - 5.1e-53 180.6 0.1 1.1e-45 156.5 0.1 2.1 2 0 0 2 2 2 2 Amidase Sel1 PF08238.12 KXG50608.1 - 2.6e-33 113.7 35.7 4.7e-05 23.9 0.1 11.2 11 0 0 11 11 11 8 Sel1 repeat Zn_clus PF00172.18 KXG50608.1 - 0.019 15.1 6.3 0.036 14.2 6.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.17 KXG50608.1 - 0.46 10.7 12.9 38 4.7 0.1 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXG50608.1 - 1.2 9.3 7.7 32 4.9 0.0 5.1 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXG50608.1 - 9 6.3 8.0 51 3.9 0.0 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat RNA_pol_Rpb1_1 PF04997.12 KXG50609.1 - 1.6e-111 372.7 0.0 2.4e-111 372.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KXG50609.1 - 6.1e-103 343.9 0.1 9.7e-103 343.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KXG50609.1 - 1.3e-74 249.9 0.0 2.7e-74 248.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KXG50609.1 - 3.7e-64 216.1 1.9 7.7e-64 215.1 1.3 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KXG50609.1 - 5.3e-45 152.7 9.0 2.7e-44 150.5 7.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KXG50609.1 - 2.8e-44 150.8 0.0 7e-44 149.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KXG50609.1 - 7.4e-38 128.8 0.1 1.8e-37 127.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KXG50609.1 - 4.7e-17 61.3 203.6 0.0015 18.8 0.1 14.6 12 2 2 14 14 14 13 RNA polymerase Rpb1 C-terminal repeat YorP PF09629.10 KXG50609.1 - 0.17 12.1 0.0 2.9 8.2 0.0 2.6 3 0 0 3 3 3 0 YorP protein WD40 PF00400.32 KXG50610.1 - 2.8e-13 50.1 10.0 3.6e-05 24.4 0.3 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG50610.1 - 7.8e-11 42.1 0.4 0.0051 17.1 0.0 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXG50610.1 - 1.8e-05 24.7 0.1 0.07 13.0 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KXG50610.1 - 0.037 12.6 0.0 0.086 11.4 0.0 1.6 1 0 0 1 1 1 0 Cytochrome D1 heme domain Methyltransf_23 PF13489.6 KXG50611.1 - 3.5e-15 56.2 0.0 6.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG50611.1 - 8.5e-09 36.0 0.0 2.5e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG50611.1 - 9.5e-07 29.5 0.0 2.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG50611.1 - 3.7e-05 23.5 0.0 6.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG50611.1 - 3.8e-05 24.3 0.0 9.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KXG50611.1 - 0.00015 21.9 0.0 0.00032 20.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KXG50611.1 - 0.00069 19.2 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXG50611.1 - 0.0083 15.6 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 KXG50611.1 - 0.0093 15.4 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KXG50611.1 - 0.044 13.1 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KXG50611.1 - 0.05 12.9 0.0 0.27 10.5 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KXG50611.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 KXG50611.1 - 0.22 11.2 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase WD40 PF00400.32 KXG50612.1 - 7.2e-15 55.1 1.8 0.00037 21.2 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KXG50612.1 - 0.1 11.3 0.0 0.37 9.5 0.0 2.1 2 1 0 2 2 2 0 Nup133 N terminal like DUF4553 PF15090.6 KXG50613.1 - 1 8.3 36.4 1.1 8.1 36.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) Thg1 PF04446.12 KXG50614.1 - 1.5e-52 176.9 0.0 2e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KXG50614.1 - 1.5e-51 173.7 1.2 1.9e-51 173.3 1.2 1.1 1 0 0 1 1 1 1 Thg1 C terminal domain fn3 PF00041.21 KXG50615.1 - 9.7e-07 29.0 0.0 2.4e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain LNS2 PF08235.13 KXG50616.1 - 2.3e-96 321.6 0.0 3.2e-96 321.2 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KXG50616.1 - 6.3e-41 138.5 0.0 1.3e-40 137.5 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 KXG50616.1 - 0.0026 17.4 0.0 0.073 12.6 0.0 2.5 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) WRNPLPNID PF15017.6 KXG50616.1 - 0.52 11.2 18.7 1.6 9.6 18.7 1.9 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Nop14 PF04147.12 KXG50616.1 - 3.7 5.6 19.0 4.8 5.3 19.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KXG50616.1 - 4.5 5.4 10.6 6.4 4.9 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KXG50616.1 - 7.6 5.8 15.3 12 5.2 15.3 1.2 1 0 0 1 1 1 0 SDA1 TFIID-31kDa PF02291.15 KXG50617.1 - 1.1e-45 154.6 0.0 1.5e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Cmc1 PF08583.10 KXG50618.1 - 8.1e-15 54.6 5.4 1.6e-14 53.7 5.4 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 KXG50618.1 - 0.0014 18.6 0.7 0.0022 17.9 0.7 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Utp11 PF03998.13 KXG50619.1 - 9e-59 199.4 28.4 1e-58 199.1 28.4 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KXG50619.1 - 0.014 14.7 0.2 0.049 12.9 0.0 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 PhoU PF01895.19 KXG50619.1 - 0.11 13.0 2.0 0.18 12.3 0.1 2.2 2 0 0 2 2 2 0 PhoU domain MAJIN PF15077.6 KXG50619.1 - 3.6 7.3 9.7 0.69 9.7 5.7 1.8 2 0 0 2 2 2 0 Membrane-anchored junction protein CIAPIN1 PF05093.13 KXG50620.1 - 1.6e-42 144.1 3.3 2.8e-42 143.3 3.3 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KXG50620.1 - 4.1e-37 127.3 0.0 5.7e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Histidinol_dh PF00815.20 KXG50621.1 - 4e-160 533.3 3.2 5.6e-160 532.8 3.2 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KXG50621.1 - 3.4e-23 81.3 0.1 7e-23 80.2 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KXG50621.1 - 1.8e-14 53.9 0.3 4.3e-14 52.7 0.3 1.6 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 KXG50621.1 - 0.27 11.4 1.7 0.38 11.0 0.4 1.9 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Glyco_hydro_47 PF01532.20 KXG50622.1 - 7e-143 476.8 0.0 8e-143 476.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TPKR_C2 PF16920.5 KXG50622.1 - 0.066 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain MiaE_2 PF13794.6 KXG50622.1 - 0.2 11.3 0.3 0.96 9.1 0.0 2.0 3 0 0 3 3 3 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Arylsulfotran_2 PF14269.6 KXG50623.1 - 1.4e-59 201.9 5.0 1.9e-59 201.5 5.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXG50623.1 - 1.4e-17 63.7 0.5 8.6e-16 57.8 0.5 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) EF-hand_1 PF00036.32 KXG50623.1 - 0.084 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 EF hand TPR_2 PF07719.17 KXG50624.1 - 2.7e-07 30.2 14.8 0.0003 20.7 0.0 6.4 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXG50624.1 - 2e-06 28.2 2.4 0.16 12.5 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXG50624.1 - 0.0001 22.2 0.9 1.7 9.0 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXG50624.1 - 0.00034 20.3 10.1 0.0072 16.1 0.0 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXG50624.1 - 0.001 19.7 8.7 0.97 10.4 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXG50624.1 - 0.0013 18.4 0.5 8.9 6.1 0.0 5.6 7 1 1 8 8 8 1 TPR repeat TPR_7 PF13176.6 KXG50624.1 - 0.002 18.0 3.3 54 4.2 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXG50624.1 - 0.021 15.1 7.3 0.056 13.7 0.3 4.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXG50624.1 - 0.04 14.5 2.1 0.74 10.6 0.6 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXG50624.1 - 0.048 13.5 2.5 21 5.2 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Sod_Fe_N PF00081.22 KXG50625.1 - 1e-33 115.6 2.3 1e-33 115.6 2.3 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 KXG50625.1 - 7.1e-32 109.6 0.1 1.7e-31 108.4 0.0 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain adh_short_C2 PF13561.6 KXG50626.1 - 2.8e-44 151.4 0.6 3.4e-44 151.1 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG50626.1 - 2.9e-40 137.8 0.4 3.7e-40 137.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG50626.1 - 3.3e-10 40.2 0.2 4.8e-10 39.6 0.2 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXG50626.1 - 0.04 13.3 0.0 0.72 9.2 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Amidase PF01425.21 KXG50627.1 - 1.6e-89 301.0 0.0 2e-89 300.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Aa_trans PF01490.18 KXG50628.1 - 9.3e-14 50.9 26.2 2.3e-10 39.8 11.5 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Cyt_c_ox_IV PF12270.8 KXG50628.1 - 0.031 14.4 1.4 0.031 14.4 1.4 4.7 4 1 0 5 5 5 0 Cytochrome c oxidase subunit IV NLPC_P60 PF00877.19 KXG50630.1 - 9.5e-21 73.8 0.0 1.7e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family SH3_3 PF08239.11 KXG50630.1 - 0.00052 20.2 0.2 0.001 19.3 0.2 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain DUF1175 PF06672.11 KXG50630.1 - 0.00084 19.1 0.0 0.87 9.2 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1175) Amidase_5 PF05382.13 KXG50630.1 - 0.009 15.9 0.9 0.016 15.1 0.1 1.9 1 1 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase Pyr_redox_2 PF07992.14 KXG50631.1 - 3.6e-37 128.2 0.0 5.5e-34 117.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG50631.1 - 1.4e-08 35.2 0.0 1.6e-07 31.8 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG50631.1 - 0.023 14.9 0.0 9.8 6.5 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXG50631.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RTA1 PF04479.13 KXG50632.1 - 1.1e-70 237.5 11.6 1.1e-70 237.5 11.6 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF3382 PF11862.8 KXG50632.1 - 0.083 13.2 3.8 1.6 9.1 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) DUF4131 PF13567.6 KXG50632.1 - 3.6 7.2 6.0 3.9 7.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ank_2 PF12796.7 KXG50633.1 - 2.7e-47 159.3 0.1 2.5e-13 50.4 0.2 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG50633.1 - 4.2e-36 122.9 5.0 1.1e-12 48.2 0.1 6.1 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KXG50633.1 - 1.3e-34 117.1 6.9 0.00015 22.0 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 KXG50633.1 - 3.7e-34 112.9 6.2 0.00042 20.5 0.0 8.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KXG50633.1 - 2.2e-30 104.3 7.3 2.8e-07 30.7 0.0 6.9 2 2 5 7 7 7 6 Ankyrin repeats (many copies) CorA PF01544.18 KXG50633.1 - 2e-13 50.3 1.1 4.3e-13 49.2 1.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein S6PP_C PF08472.10 KXG50634.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal Aminotran_1_2 PF00155.21 KXG50635.1 - 3.6e-15 56.0 0.0 4.7e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KXG50635.1 - 0.0023 16.8 0.0 0.016 14.0 0.0 1.9 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Pectate_lyase_3 PF12708.7 KXG50636.1 - 5.3e-101 336.9 19.5 5.7e-88 294.3 5.4 3.4 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KXG50636.1 - 5.3e-07 29.2 0.9 0.027 14.2 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase NosD PF05048.13 KXG50636.1 - 0.0012 18.2 1.0 0.0032 16.8 1.0 1.8 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Cation_efflux PF01545.21 KXG50637.1 - 1.2e-14 54.5 6.7 1.5e-14 54.2 6.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXG50637.1 - 1.2e-09 38.2 0.3 3.2e-09 36.8 0.3 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Adaptin_binding PF10199.9 KXG50637.1 - 1.4 9.5 3.9 3.8 8.2 3.9 1.7 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Pro_isomerase PF00160.21 KXG50639.1 - 8.8e-45 152.8 0.5 1e-44 152.6 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Metallophos PF00149.28 KXG50640.1 - 1.6e-13 51.6 0.1 2.2e-13 51.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXG50640.1 - 2.2e-10 41.0 0.4 4e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Transp_inhibit PF18791.1 KXG50640.1 - 0.16 11.5 0.0 0.51 9.9 0.0 1.8 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain Methyltransf_25 PF13649.6 KXG50641.1 - 7.7e-15 55.4 0.0 1.6e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG50641.1 - 6.9e-14 52.3 0.0 1.6e-13 51.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG50641.1 - 3.1e-12 46.5 0.0 4.3e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG50641.1 - 1.7e-10 41.5 0.0 3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG50641.1 - 5.6e-08 32.8 0.0 8.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXG50641.1 - 7.8e-05 22.3 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KXG50641.1 - 0.0035 16.8 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 KXG50641.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KXG50641.1 - 0.037 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CheR PF01739.18 KXG50641.1 - 0.061 12.8 0.0 2.1 7.8 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.18 KXG50641.1 - 0.075 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 KXG50641.1 - 0.21 10.9 0.0 0.38 10.0 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family LPMO_10 PF03067.15 KXG50642.1 - 2e-13 51.5 1.2 2e-13 51.5 1.2 1.5 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DUF5642 PF18702.1 KXG50642.1 - 0.0017 18.1 7.0 0.0038 17.0 7.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5642) ADH_zinc_N_2 PF13602.6 KXG50643.1 - 4.5e-25 89.2 0.0 7.7e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXG50643.1 - 7.7e-19 68.0 0.0 1.1e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXG50643.1 - 0.0034 16.9 0.0 0.013 14.9 0.0 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Methyltransf_23 PF13489.6 KXG50644.1 - 3.7e-11 43.1 0.0 5.4e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG50644.1 - 1e-06 29.4 0.0 2.6e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG50644.1 - 0.0058 17.3 0.0 0.015 16.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG50644.1 - 0.0072 16.9 0.0 0.019 15.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXG50644.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain Methyltransf_31 PF13847.6 KXG50644.1 - 0.031 14.1 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KXG50644.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 KXG50644.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KXG50644.1 - 0.14 11.5 0.0 5 6.4 0.0 2.8 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KXG50644.1 - 0.2 11.0 0.0 0.41 10.0 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GAT PF03127.14 KXG50645.1 - 5.8e-17 61.8 0.0 1.2e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 GAT domain VHS PF00790.19 KXG50645.1 - 0.004 17.0 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 VHS domain HAD_2 PF13419.6 KXG50646.1 - 1.4e-12 48.1 0.0 9.9e-12 45.3 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXG50646.1 - 0.00025 21.4 0.0 0.012 15.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase EcoEI_R_C PF08463.10 KXG50646.1 - 0.032 14.4 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 EcoEI R protein C-terminal 2-Hacid_dh_C PF02826.19 KXG50647.1 - 1.8e-54 183.8 0.0 3.1e-54 183.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_L22 PF00237.19 KXG50647.1 - 4.3e-39 132.9 0.7 3.1e-38 130.1 0.0 2.7 2 1 1 3 3 3 1 Ribosomal protein L22p/L17e 2-Hacid_dh PF00389.30 KXG50647.1 - 1.1e-18 67.2 0.0 2.3e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXG50647.1 - 0.0011 19.2 0.6 0.0025 18.0 0.3 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.12 KXG50648.1 - 1.4e-28 98.9 0.9 2.7e-28 98.0 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KXG50648.1 - 4.5e-14 52.4 0.5 2e-06 27.5 0.0 2.3 1 1 1 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 KXG50648.1 - 5.9e-13 48.9 0.4 2e-12 47.2 0.4 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KXG50648.1 - 0.023 15.0 0.3 0.045 14.0 0.3 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KXG50648.1 - 0.032 13.9 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N_2 PF13602.6 KXG50648.1 - 0.034 15.2 0.0 0.08 14.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KXG50649.1 - 6.2e-46 156.8 0.7 7.1e-46 156.6 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG50649.1 - 8.5e-44 149.3 0.4 1.1e-43 149.0 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG50649.1 - 5.1e-12 46.1 0.3 7e-12 45.6 0.3 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXG50649.1 - 1.9e-05 24.6 0.1 4.5e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXG50649.1 - 2.7e-05 23.8 0.2 6.2e-05 22.6 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG50649.1 - 5.6e-05 22.7 0.1 0.0001 21.8 0.1 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXG50649.1 - 0.00022 20.5 0.0 0.00029 20.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KXG50649.1 - 0.00059 20.1 0.0 0.00087 19.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 KXG50649.1 - 0.057 13.5 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ACT_7 PF13840.6 KXG50649.1 - 0.089 12.6 0.2 0.48 10.2 0.0 2.2 2 0 0 2 2 2 0 ACT domain Fungal_trans PF04082.18 KXG50650.1 - 6.5e-11 41.8 0.0 1.9e-09 37.0 0.0 2.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG50650.1 - 9.1e-07 28.9 9.8 1.6e-06 28.1 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 KXG50651.1 - 1.3e-51 175.5 0.1 1.6e-51 175.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG50651.1 - 1.3e-48 165.0 0.0 1.8e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG50651.1 - 1.2e-08 35.1 0.3 3.3e-08 33.6 0.0 1.8 2 1 1 3 3 3 1 KR domain Epimerase PF01370.21 KXG50651.1 - 0.00038 20.0 0.0 0.00046 19.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KXG50651.1 - 0.031 13.6 0.0 0.092 12.1 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 KXG50651.1 - 0.037 13.1 0.1 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXG50651.1 - 0.07 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Ferric_reduct PF01794.19 KXG50652.1 - 7.8e-26 90.6 7.1 2.1e-25 89.2 7.1 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXG50652.1 - 7.7e-13 48.8 0.0 4.3e-08 33.4 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXG50652.1 - 2.3e-11 43.8 0.1 1.5e-06 28.3 0.1 2.6 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KXG50652.1 - 0.067 13.9 0.0 0.39 11.4 0.0 2.3 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain ABC2_membrane PF01061.24 KXG50653.1 - 1.4e-88 295.7 55.2 3.1e-48 164.0 22.2 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KXG50653.1 - 4.9e-38 130.7 0.0 2.9e-18 66.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXG50653.1 - 6e-33 112.6 1.3 4.2e-32 109.9 0.2 3.5 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KXG50653.1 - 1.5e-18 67.2 0.2 4e-18 65.8 0.2 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KXG50653.1 - 6.6e-07 29.4 0.5 7.6e-05 22.7 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KXG50653.1 - 4.2e-05 24.0 0.1 0.0061 17.0 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KXG50653.1 - 4.4e-05 23.1 0.0 0.00063 19.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXG50653.1 - 0.00063 19.4 1.4 0.028 14.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KXG50653.1 - 0.0015 18.4 0.2 2.9 7.6 0.1 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KXG50653.1 - 0.0021 18.6 0.0 0.037 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXG50653.1 - 0.0078 16.4 0.8 0.11 12.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.19 KXG50653.1 - 0.0096 15.4 0.0 0.45 9.9 0.0 2.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXG50653.1 - 0.023 15.0 0.4 1.3 9.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain Abhydrolase_5 PF12695.7 KXG50653.1 - 0.024 14.4 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_17 PF13207.6 KXG50653.1 - 0.026 15.0 0.0 1.7 9.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KXG50653.1 - 0.04 14.3 0.0 11 6.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 KXG50653.1 - 0.046 13.5 0.1 2.7 7.7 0.0 2.6 3 0 0 3 3 2 0 IstB-like ATP binding protein NACHT PF05729.12 KXG50653.1 - 0.062 13.2 3.7 3.8 7.4 0.2 3.2 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.6 KXG50653.1 - 0.073 12.8 1.1 3.9 7.1 0.3 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KXG50653.1 - 0.18 12.3 0.0 31 5.0 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KXG50653.1 - 0.26 10.9 0.5 1.3 8.6 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.7 KXG50653.1 - 1.7 7.6 42.7 0.066 12.3 14.1 3.1 2 1 1 3 3 3 0 ABC-2 family transporter protein UBX PF00789.20 KXG50654.1 - 2e-10 40.7 0.0 4.9e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KXG50654.1 - 3.1e-10 39.7 0.0 5.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain dCMP_cyt_deam_1 PF00383.23 KXG50654.1 - 0.21 11.5 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region DUF1682 PF07946.14 KXG50654.1 - 1.2 8.3 6.6 1.1 8.4 5.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Pan3_PK PF18101.1 KXG50655.1 - 9.9e-61 203.7 0.2 1.5e-60 203.2 0.2 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KXG50655.1 - 4.7e-06 26.2 0.0 7.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG50655.1 - 0.072 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase MMR_HSR1_Xtn PF16897.5 KXG50655.1 - 0.11 12.5 0.1 0.98 9.5 0.0 2.2 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Fasciclin PF02469.22 KXG50656.1 - 4.5e-40 136.8 0.0 9.2e-23 80.9 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Lactamase_B_4 PF13691.6 KXG50656.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 tRNase Z endonuclease Dioxygenase_C PF00775.21 KXG50657.1 - 6.3e-40 136.5 0.0 8.6e-40 136.1 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXG50657.1 - 2.4e-31 107.4 0.0 4.3e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus ACOX PF01756.19 KXG50657.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA oxidase Zn_clus PF00172.18 KXG50658.1 - 0.059 13.5 9.9 0.14 12.3 9.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.22 KXG50659.1 - 1.3e-22 79.2 0.7 1.6e-22 78.9 0.7 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 KXG50659.1 - 0.0026 18.3 7.1 0.0041 17.6 7.1 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 DUF150_C PF17384.2 KXG50659.1 - 0.0091 16.1 0.1 0.015 15.5 0.1 1.3 1 0 0 1 1 1 1 RimP C-terminal SH3 domain Vps39_2 PF10367.9 KXG50660.1 - 4.5e-06 27.1 0.0 1.5e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KXG50660.1 - 0.0065 16.7 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 CASP_C PF08172.12 KXG50661.1 - 3e-89 298.7 2.0 3e-89 298.7 2.0 3.3 2 1 3 5 5 5 1 CASP C terminal ZapB PF06005.12 KXG50661.1 - 0.061 13.8 0.4 0.061 13.8 0.4 6.8 5 1 0 5 5 5 0 Cell division protein ZapB YqjK PF13997.6 KXG50661.1 - 1.4 9.2 4.2 1.1e+02 3.2 0.1 4.1 3 0 0 3 3 3 0 YqjK-like protein SlyX PF04102.12 KXG50661.1 - 2.6 8.7 0.0 2.6 8.7 0.0 5.9 6 0 0 6 6 6 0 SlyX DUF4407 PF14362.6 KXG50661.1 - 2.6 7.3 44.6 2.3 7.5 0.1 4.4 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) betaPIX_CC PF16523.5 KXG50661.1 - 2.7 7.9 17.7 1.8 8.5 4.4 4.1 3 1 0 3 3 3 0 betaPIX coiled coil Cep57_MT_bd PF06657.13 KXG50661.1 - 4.8 7.7 25.6 0.94 10.0 2.1 4.8 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF3455 PF11937.8 KXG50662.1 - 1.4e-47 162.0 0.1 1.9e-47 161.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 KXG50662.1 - 3e-30 104.2 0.1 5.6e-30 103.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) Fibrillarin PF01269.17 KXG50663.1 - 9.9e-105 348.7 0.0 1.2e-104 348.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KXG50663.1 - 2.4e-06 27.4 0.1 4.2e-06 26.6 0.1 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KXG50663.1 - 0.016 15.0 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KXG50663.1 - 0.054 13.1 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Epimerase PF01370.21 KXG50664.1 - 3.7e-20 72.4 0.0 4.9e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXG50664.1 - 2e-13 50.0 0.0 2.7e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXG50664.1 - 4.7e-12 45.9 0.0 1.1e-11 44.8 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXG50664.1 - 2.3e-07 30.2 0.0 3.2e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXG50664.1 - 0.00016 21.7 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KXG50664.1 - 0.00029 20.4 0.0 0.00073 19.0 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KXG50664.1 - 0.00044 19.5 0.0 0.044 12.9 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KXG50664.1 - 0.0021 17.3 0.0 0.0041 16.3 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KXG50664.1 - 0.0034 17.3 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXG50664.1 - 0.0042 17.3 0.0 0.0068 16.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 KXG50664.1 - 0.0046 17.1 0.0 0.016 15.3 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KXG50664.1 - 0.015 15.7 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Peptidase_M16 PF00675.20 KXG50665.1 - 2.4e-56 189.8 0.1 7.8e-56 188.2 0.2 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXG50665.1 - 5.5e-41 140.6 0.0 1.1e-38 133.1 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain Methyltr_RsmB-F PF01189.17 KXG50666.1 - 2.8e-32 112.0 0.0 3.7e-25 88.7 0.0 3.2 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F ABC_membrane PF00664.23 KXG50667.1 - 4.5e-93 311.9 38.0 1.1e-49 169.5 18.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXG50667.1 - 1.5e-67 226.3 0.0 2.1e-32 112.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXG50667.1 - 4.1e-11 42.7 9.1 0.00039 19.9 0.0 4.8 4 2 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXG50667.1 - 2e-09 38.0 3.0 8.8e-05 23.0 0.1 3.4 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KXG50667.1 - 8.5e-09 35.8 1.5 0.004 17.4 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXG50667.1 - 8.3e-08 31.9 0.1 0.00058 19.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXG50667.1 - 2.4e-07 30.8 0.0 0.014 15.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KXG50667.1 - 8e-07 29.0 1.2 0.046 13.4 0.0 3.9 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 KXG50667.1 - 7.5e-06 25.0 0.3 0.023 13.5 0.1 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 KXG50667.1 - 3.9e-05 23.5 0.0 0.01 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KXG50667.1 - 0.00015 21.3 0.6 0.28 10.7 0.0 2.8 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_23 PF13476.6 KXG50667.1 - 0.00021 21.9 2.7 0.065 13.7 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 KXG50667.1 - 0.00033 20.6 3.1 2.7 7.7 0.0 4.0 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KXG50667.1 - 0.00052 19.6 0.2 2.1 7.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KXG50667.1 - 0.00066 20.1 1.3 3.8 8.0 0.3 4.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXG50667.1 - 0.0015 18.5 0.0 2.8 8.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 KXG50667.1 - 0.0017 18.1 0.0 4 7.0 0.0 3.4 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 KXG50667.1 - 0.0018 18.5 0.0 1.9 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXG50667.1 - 0.0021 17.8 1.5 1.7 8.3 0.0 3.7 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_28 PF13521.6 KXG50667.1 - 0.0028 17.9 0.4 0.18 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KXG50667.1 - 0.0046 16.2 0.0 1.3 8.3 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Rad17 PF03215.15 KXG50667.1 - 0.0065 16.4 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain SbcCD_C PF13558.6 KXG50667.1 - 0.0089 16.2 1.7 2.9 8.2 0.1 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 KXG50667.1 - 0.0096 15.1 0.0 1 8.4 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit AAA_24 PF13479.6 KXG50667.1 - 0.011 15.4 0.0 3.7 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXG50667.1 - 0.015 14.5 1.3 1.4 8.1 0.2 3.0 2 1 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 KXG50667.1 - 0.02 15.4 0.0 5.8 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KXG50667.1 - 0.038 13.6 0.0 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PRK PF00485.18 KXG50667.1 - 0.044 13.5 0.1 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.21 KXG50667.1 - 0.07 12.5 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KXG50667.1 - 0.074 13.4 0.0 13 6.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Synapsin_N PF10581.9 KXG50667.1 - 0.093 12.7 0.0 0.58 10.2 0.0 2.2 2 0 0 2 2 2 0 Synapsin N-terminal MMR_HSR1 PF01926.23 KXG50667.1 - 0.11 12.5 0.1 25 5.0 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zn_clus PF00172.18 KXG50668.1 - 0.0007 19.7 2.9 0.0022 18.1 2.9 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXG50668.1 - 0.019 14.0 0.4 0.031 13.3 0.4 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain DIT1_PvcA PF05141.12 KXG50670.1 - 4.3e-96 321.6 0.0 5.2e-96 321.3 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein NAD_binding_4 PF07993.12 KXG50671.1 - 4.4e-32 111.2 0.0 7.4e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXG50671.1 - 8.3e-23 80.7 0.0 1.4e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KXG50671.1 - 7.5e-11 41.9 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXG50671.1 - 3.9e-07 30.3 0.1 1e-06 29.0 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KXG50671.1 - 0.0037 17.2 0.1 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KXG50671.1 - 0.044 13.2 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXG50671.1 - 0.047 12.8 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KXG50671.1 - 0.052 14.0 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXG50671.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glyco_hydro_35 PF01301.19 KXG50672.1 - 4.2e-100 335.4 0.0 5.8e-100 335.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KXG50672.1 - 5.4e-62 208.8 2.0 8.9e-62 208.1 2.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KXG50672.1 - 2.3e-59 198.9 5.9 2.9e-33 114.8 0.2 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KXG50672.1 - 4.5e-23 80.6 0.1 1e-22 79.4 0.1 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 CARDB PF07705.11 KXG50672.1 - 0.15 12.3 0.3 53 4.1 0.0 3.5 3 0 0 3 3 3 0 CARDB DUF3060 PF11259.8 KXG50672.1 - 0.5 10.1 3.0 2.5 7.9 0.2 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3060) CYSTM PF12734.7 KXG50674.1 - 0.0049 17.2 76.8 2.2e+03 -1.0 58.8 5.4 2 2 0 2 2 2 0 Cysteine-rich TM module stress tolerance RNA_pol_Rpb5_C PF01191.19 KXG50675.1 - 6e-34 115.7 0.1 9.6e-34 115.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KXG50675.1 - 2.7e-24 85.6 0.0 4e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KXG50675.1 - 0.015 15.3 0.0 0.036 14.1 0.0 1.6 2 0 0 2 2 2 0 Restriction endonuclease Zw10 PF06248.13 KXG50676.1 - 0.00058 18.6 10.2 0.00058 18.6 10.2 2.2 2 1 1 3 3 3 1 Centromere/kinetochore Zw10 EzrA PF06160.12 KXG50676.1 - 0.002 16.4 18.3 0.002 16.4 18.3 3.6 2 1 1 3 3 3 3 Septation ring formation regulator, EzrA Syntaxin PF00804.25 KXG50676.1 - 0.0027 17.4 12.7 0.0027 17.4 12.7 4.1 2 1 2 4 4 4 2 Syntaxin ABC_tran_CTD PF16326.5 KXG50676.1 - 0.0064 16.7 5.5 0.0064 16.7 5.5 7.1 3 2 5 8 8 8 1 ABC transporter C-terminal domain DUF2968 PF11180.8 KXG50676.1 - 0.015 15.0 9.3 0.015 15.0 9.3 4.3 4 1 0 4 4 4 0 Protein of unknown function (DUF2968) HalX PF08663.10 KXG50676.1 - 0.1 12.9 0.3 0.1 12.9 0.3 5.3 5 3 2 7 7 7 0 HalX domain Fib_alpha PF08702.10 KXG50676.1 - 1.3 9.2 34.7 0.38 10.9 6.3 4.9 2 1 3 5 5 5 0 Fibrinogen alpha/beta chain family MtrG PF04210.13 KXG50676.1 - 1.6 8.6 4.4 20 5.1 0.0 3.8 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G IL3 PF02059.15 KXG50676.1 - 1.8 8.7 13.6 0.38 10.8 3.5 3.0 1 1 2 3 3 3 0 Interleukin-3 DUF1664 PF07889.12 KXG50676.1 - 2.9 8.0 21.9 4.5 7.3 1.8 4.3 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) MARVEL PF01284.23 KXG50677.1 - 4.5 7.3 15.2 9.1 6.3 0.2 3.2 2 1 1 3 3 3 0 Membrane-associating domain Aminotran_1_2 PF00155.21 KXG50678.1 - 4.8e-60 203.6 0.0 6e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CAP160 PF07918.11 KXG50678.1 - 9.5 6.1 6.4 3.9 7.3 2.3 2.2 2 0 0 2 2 2 0 CAP160 repeat DUF1115 PF06544.12 KXG50679.1 - 5.1e-11 42.9 0.0 7.8e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Tam41_Mmp37 PF09139.11 KXG50680.1 - 1.7e-129 431.9 0.0 2e-129 431.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial BIR PF00653.21 KXG50681.1 - 1.8e-46 156.7 6.1 1.2e-22 80.3 0.1 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C2H2_jaz PF12171.8 KXG50682.1 - 4.2e-08 33.3 0.7 6.8e-08 32.6 0.7 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXG50682.1 - 2.3e-05 24.6 0.9 3.8e-05 23.9 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KXG50682.1 - 0.0074 16.7 0.6 0.013 15.9 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KXG50682.1 - 0.16 12.1 0.3 0.26 11.4 0.3 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger DUF3340 PF11818.8 KXG50682.1 - 0.99 9.6 16.1 0.65 10.1 7.5 2.1 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Pyrid_ox_like PF16242.5 KXG50683.1 - 2e-20 72.9 0.0 3.1e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KXG50683.1 - 6.3e-08 32.7 0.0 1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 KXG50683.1 - 0.058 13.1 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative FMN-binding domain AMP-binding PF00501.28 KXG50684.1 - 3.3e-134 447.7 0.0 3.2e-70 236.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.12 KXG50684.1 - 2.8e-37 128.3 0.0 6.1e-37 127.2 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.20 KXG50684.1 - 6.6e-36 123.9 0.0 1e-35 123.3 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KXG50684.1 - 7.6e-20 71.0 0.9 8.3e-10 38.9 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXG50684.1 - 1.7e-06 28.9 0.0 0.00072 20.5 0.0 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 KXG50684.1 - 0.00013 21.6 0.0 0.00029 20.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ATP-grasp_4 PF13535.6 KXG50684.1 - 0.046 13.3 0.1 0.088 12.4 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain GDP_Man_Dehyd PF16363.5 KXG50684.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXG50684.1 - 0.19 10.7 0.0 6.2 5.7 0.0 2.6 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_2 PF00891.18 KXG50685.1 - 9.8e-18 64.2 0.0 1.4e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KXG50685.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain Tctex-1 PF03645.13 KXG50685.1 - 0.044 14.0 0.0 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 Tctex-1 family MFS_1 PF07690.16 KXG50686.1 - 2.6e-38 131.9 51.4 2.6e-38 131.9 51.4 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG50686.1 - 1.3e-09 37.5 13.5 1.3e-09 37.5 13.5 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter ADH_N PF08240.12 KXG50687.1 - 5.9e-09 35.8 0.0 1.3e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG50687.1 - 2.7e-06 27.4 0.2 4.5e-06 26.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2001 PF09393.10 KXG50687.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Phage tail tube protein TFIID-18kDa PF02269.16 KXG50688.1 - 7.8e-27 93.1 0.2 1.5e-25 89.0 0.1 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 KXG50688.1 - 0.023 14.8 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 hTAFII28-like protein conserved region TP_methylase PF00590.20 KXG50690.1 - 6.5e-23 81.8 0.2 1e-22 81.2 0.2 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases MFS_1 PF07690.16 KXG50691.1 - 1.3e-15 57.2 34.7 1.3e-15 57.2 34.7 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 KXG50691.1 - 0.021 13.2 0.3 0.038 12.4 0.3 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector Arylsulfotran_2 PF14269.6 KXG50693.1 - 1.5e-58 198.5 9.4 2.3e-58 197.9 9.4 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXG50693.1 - 1.7e-20 73.3 8.8 1.2e-18 67.2 8.8 2.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Sulfotransfer_4 PF17784.1 KXG50694.1 - 4.3e-74 249.0 0.0 5.2e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXG50694.1 - 0.00029 21.3 0.1 0.0031 17.9 0.0 2.2 1 1 1 2 2 2 1 Sulfotransferase family Ist1 PF03398.14 KXG50695.1 - 8.2e-43 146.2 0.7 2.1e-22 79.8 2.8 2.3 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway Cys_Met_Meta_PP PF01053.20 KXG50696.1 - 8.7e-62 208.8 0.0 2.1e-61 207.6 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXG50696.1 - 0.009 15.2 0.0 0.018 14.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXG50696.1 - 0.051 12.5 0.0 0.095 11.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Importin_rep_5 PF18816.1 KXG50696.1 - 0.061 13.6 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 Importin repeat Fungal_trans_2 PF11951.8 KXG50697.1 - 6.7e-28 97.6 0.2 7.6e-28 97.4 0.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain PsbJ PF01788.17 KXG50698.1 - 0.019 14.8 0.1 0.026 14.4 0.1 1.2 1 0 0 1 1 1 0 PsbJ DUF3169 PF11368.8 KXG50698.1 - 0.033 13.7 0.0 0.037 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) SUN PF03856.13 KXG50699.1 - 1.7e-80 270.0 7.4 2.6e-80 269.4 7.4 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) SOG2 PF10428.9 KXG50699.1 - 2.4 7.2 23.5 3.3 6.8 23.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Cutinase PF01083.22 KXG50700.1 - 4.6e-50 170.0 8.4 7.1e-50 169.4 8.4 1.3 1 0 0 1 1 1 1 Cutinase LCM PF04072.14 KXG50700.1 - 7.9e-17 61.8 0.0 1.3e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase PE-PPE PF08237.11 KXG50700.1 - 0.00036 20.2 0.2 0.00059 19.5 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain zf-RING_2 PF13639.6 KXG50701.1 - 1e-07 32.2 9.0 2e-07 31.2 9.0 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KXG50701.1 - 5.6e-05 23.2 6.2 0.00014 22.0 6.2 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KXG50701.1 - 0.00013 21.9 2.2 0.00034 20.6 2.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KXG50701.1 - 0.00018 21.7 8.0 0.00043 20.5 8.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXG50701.1 - 0.00037 20.3 9.6 0.00078 19.3 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXG50701.1 - 0.0049 16.7 8.4 0.0099 15.7 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KXG50701.1 - 0.16 12.1 7.6 0.39 10.9 7.6 1.7 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.22 KXG50701.1 - 0.21 11.5 5.8 0.47 10.4 5.8 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_11 PF17123.5 KXG50701.1 - 0.24 11.2 2.9 0.58 10.0 2.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KXG50701.1 - 0.28 10.8 6.2 0.57 9.8 6.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KXG50701.1 - 0.33 10.8 6.6 5.5 6.9 0.5 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KXG50701.1 - 0.59 10.5 8.2 1.1 9.6 8.2 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 KXG50701.1 - 1.1 9.1 5.7 2.1 8.2 5.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KXG50701.1 - 2.5 8.1 7.2 4.7 7.2 7.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 KXG50701.1 - 2.9 8.0 5.7 6.3 6.9 5.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_9 PF13901.6 KXG50701.1 - 3 7.8 7.8 13 5.7 7.3 2.1 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Prok-RING_4 PF14447.6 KXG50701.1 - 4.7 7.1 6.2 11 6.0 6.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DEAD_2 PF06733.15 KXG50702.1 - 4.8e-56 189.1 1.0 6.5e-56 188.7 0.1 1.7 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 KXG50702.1 - 6.2e-50 169.5 3.1 3.8e-45 153.9 0.8 2.8 3 0 0 3 3 3 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KXG50702.1 - 7.8e-44 149.9 0.0 2.1e-43 148.5 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 KXG50702.1 - 5.8e-05 23.2 0.3 0.0035 17.4 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXG50702.1 - 0.0047 16.7 0.0 0.65 9.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXG50702.1 - 0.013 15.8 0.3 2.4 8.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KXG50702.1 - 0.029 13.6 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.23 KXG50702.1 - 0.067 11.9 0.0 0.42 9.3 0.0 2.0 1 1 0 1 1 1 0 SNF2 family N-terminal domain ADH_N PF08240.12 KXG50703.1 - 1.6e-29 102.0 0.1 2.7e-29 101.2 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG50703.1 - 2.4e-17 63.1 0.0 4.1e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG50703.1 - 0.00042 21.4 0.0 0.00089 20.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KXG50703.1 - 0.00051 19.9 0.3 0.001 18.9 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated RNA_pol_Rpb1_5 PF04998.17 KXG50704.1 - 1.5e-86 290.2 0.3 2.8e-86 289.3 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KXG50704.1 - 7.3e-67 224.7 0.1 1.6e-66 223.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KXG50704.1 - 1.5e-31 109.4 0.0 3.5e-30 105.0 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KXG50704.1 - 5.2e-27 95.0 1.8 2.5e-26 92.7 0.0 2.9 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KXG50704.1 - 3.7e-16 59.0 0.0 3.7e-16 59.0 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 PRP3 PF08572.10 KXG50705.1 - 1.1e-71 241.2 12.7 1.1e-71 241.2 12.7 1.8 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KXG50705.1 - 1.8e-46 157.9 0.0 1.8e-46 157.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Gar1 PF04410.14 KXG50706.1 - 3.2e-45 153.7 0.6 3.2e-45 153.7 0.6 2.0 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Cwf_Cwc_15 PF04889.12 KXG50706.1 - 0.0053 16.5 11.0 0.0053 16.5 11.0 3.1 3 0 0 3 3 3 2 Cwf15/Cwc15 cell cycle control protein DUF3445 PF11927.8 KXG50707.1 - 3.3e-83 278.7 0.0 4.6e-83 278.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_transf_22 PF03901.17 KXG50707.1 - 1.2e-81 275.1 21.9 1.5e-81 274.8 21.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Exo5 PF09810.9 KXG50708.1 - 6.4e-140 466.8 0.0 9.4e-140 466.3 0.0 1.2 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease Mpv17_PMP22 PF04117.12 KXG50708.1 - 1.1e-15 57.6 0.2 2.8e-15 56.3 0.2 1.8 1 0 0 1 1 1 1 Mpv17 / PMP22 family PDDEXK_1 PF12705.7 KXG50708.1 - 0.062 13.2 0.0 27 4.5 0.0 3.1 2 1 0 2 2 2 0 PD-(D/E)XK nuclease superfamily MFS_1 PF07690.16 KXG50709.1 - 3.5e-38 131.5 51.3 6.5e-38 130.5 45.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Histone PF00125.24 KXG50710.1 - 1e-51 174.7 2.5 1.1e-51 174.6 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXG50710.1 - 6e-06 26.6 0.0 9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXG50710.1 - 4.9e-05 23.4 0.5 7.4e-05 22.8 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KXG50710.1 - 6.5e-05 23.5 1.2 7.7e-05 23.3 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KXG50710.1 - 0.0032 17.7 0.3 0.0065 16.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXG50710.1 - 0.026 14.6 0.2 0.042 13.9 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KXG50711.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KXG50711.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KXG50711.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXG50711.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KXG50711.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KXG50711.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXG50711.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KXG50711.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KXG50711.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region zf-C2H2 PF00096.26 KXG50712.1 - 7.3e-09 35.6 19.2 3.4e-05 24.1 1.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXG50712.1 - 9.1e-06 26.1 13.5 0.0098 16.7 0.7 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-BED PF02892.15 KXG50712.1 - 0.093 12.8 2.7 0.33 11.0 1.8 2.3 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 KXG50712.1 - 2.3 8.8 19.2 2.8 8.5 1.5 4.8 5 0 0 5 5 5 0 Zinc-finger double domain zf-Di19 PF05605.12 KXG50712.1 - 2.7 8.4 7.7 1.6 9.1 2.3 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Sulfotransfer_4 PF17784.1 KXG50713.1 - 2.9e-52 177.6 0.0 3.4e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXG50713.1 - 1.5e-07 32.0 0.1 0.0017 18.8 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family OAD_gamma PF04277.13 KXG50714.1 - 0.23 12.1 1.2 0.54 10.9 1.2 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain p450 PF00067.22 KXG50715.1 - 4.4e-61 207.0 0.0 8.5e-61 206.1 0.0 1.4 1 1 1 2 2 2 1 Cytochrome P450 Ntox34 PF15606.6 KXG50715.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 34 EPSP_synthase PF00275.20 KXG50716.1 - 1.4e-128 429.1 0.0 2.9e-128 428.1 0.0 1.5 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KXG50716.1 - 1e-97 326.4 0.0 1.7e-97 325.7 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KXG50716.1 - 2.2e-59 201.5 0.0 4.9e-59 200.4 0.0 1.6 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KXG50716.1 - 3.9e-40 137.6 0.0 1.4e-39 135.8 0.0 1.9 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KXG50716.1 - 1.2e-24 86.4 0.0 3.2e-24 85.0 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KXG50716.1 - 1.9e-07 31.0 0.0 4.6e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 KXG50716.1 - 2.4e-07 30.4 0.5 8.4e-07 28.7 0.1 2.1 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KXG50716.1 - 0.0019 18.2 0.0 0.0051 16.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_16 PF13191.6 KXG50716.1 - 0.029 14.7 0.1 0.27 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KXG50716.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXG50716.1 - 0.17 12.4 0.0 0.51 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Uso1_p115_head PF04869.14 KXG50717.1 - 2.5e-108 361.9 0.0 1.3e-107 359.6 0.0 2.3 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KXG50717.1 - 1.3e-19 70.8 38.7 1.3e-19 70.8 38.7 5.6 1 1 4 5 5 4 3 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.21 KXG50717.1 - 3e-05 23.8 81.8 0.013 15.1 18.3 5.0 1 1 3 4 4 4 2 Intermediate filament protein Jnk-SapK_ap_N PF09744.9 KXG50717.1 - 0.0019 18.5 12.0 0.0019 18.5 12.0 6.0 1 1 4 5 5 4 2 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 KXG50717.1 - 0.0074 16.3 5.7 0.0074 16.3 5.7 6.2 1 1 4 6 6 6 1 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KXG50717.1 - 0.0093 16.0 17.8 0.0093 16.0 17.8 5.9 2 2 4 6 6 6 2 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 KXG50717.1 - 0.12 9.9 86.5 0.014 12.9 28.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 KXG50717.1 - 0.12 11.2 91.7 0.19 10.6 13.7 4.4 1 1 3 4 4 4 0 Spc7 kinetochore protein Tropomyosin PF00261.20 KXG50717.1 - 0.15 11.4 87.5 0.14 11.5 16.2 5.1 1 1 3 4 4 4 0 Tropomyosin Golgin_A5 PF09787.9 KXG50717.1 - 0.48 9.8 87.4 0.045 13.2 9.0 4.7 1 1 4 5 5 5 0 Golgin subfamily A member 5 DUF4686 PF15742.5 KXG50717.1 - 1.1 8.3 86.5 0.13 11.4 26.9 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4686) AAA_13 PF13166.6 KXG50717.1 - 1.3 7.6 72.4 0.0086 14.8 18.8 3.7 1 1 4 5 5 5 0 AAA domain Pox_A_type_inc PF04508.12 KXG50717.1 - 1.7 8.6 7.9 43 4.2 0.4 5.3 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat FAM184 PF15665.5 KXG50717.1 - 7.7 6.2 85.0 0.011 15.6 23.9 4.1 1 1 3 4 4 3 0 Family with sequence similarity 184, A and B XRN_M PF17846.1 KXG50718.1 - 1.6e-147 492.1 1.6 1.7e-146 488.6 0.0 2.6 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KXG50718.1 - 1.3e-99 332.5 1.8 5.2e-99 330.6 0.0 2.1 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 KXG50718.1 - 0.17 12.0 4.2 0.34 11.1 4.2 1.5 1 0 0 1 1 1 0 Zinc knuckle tRNA-synt_1 PF00133.22 KXG50719.1 - 5.9e-222 738.2 0.0 1e-221 737.4 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXG50719.1 - 1.7e-23 83.3 0.0 3.8e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KXG50719.1 - 1.5e-14 53.5 0.1 1.9e-06 26.9 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) Sfi1 PF08457.10 KXG50720.1 - 2.8e-211 703.0 93.3 5.5e-210 698.7 84.7 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein Rav1p_C PF12234.8 KXG50721.1 - 4.4e-280 930.6 0.1 6.1e-280 930.2 0.1 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal p450 PF00067.22 KXG50722.1 - 8.7e-58 196.2 0.0 1.1e-57 195.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ig_mannosidase PF17753.1 KXG50723.1 - 0.11 12.2 0.1 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Ig-fold domain SGL PF08450.12 KXG50724.1 - 3.7e-24 85.6 0.9 9.8e-24 84.3 0.9 1.8 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KXG50724.1 - 5.1e-06 26.6 0.1 4.3e-05 23.6 0.1 2.3 1 1 1 2 2 2 1 Arylesterase Str_synth PF03088.16 KXG50724.1 - 4.9e-05 23.4 0.0 0.00014 21.9 0.0 1.8 1 1 0 1 1 1 1 Strictosidine synthase PD40 PF07676.12 KXG50724.1 - 0.0075 16.2 0.2 0.047 13.6 0.3 2.3 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Kin17_mid PF10357.9 KXG50725.1 - 1.5e-51 173.5 1.2 2.7e-51 172.7 1.2 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 KXG50725.1 - 0.033 14.6 3.3 0.082 13.3 3.3 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXG50725.1 - 0.086 13.2 2.7 0.2 12.0 0.5 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Ribosomal_S18 PF01084.20 KXG50725.1 - 0.26 11.6 1.2 0.68 10.2 1.2 1.7 1 0 0 1 1 1 0 Ribosomal protein S18 CarbpepA_inh PF02977.15 KXG50725.1 - 0.26 11.1 2.3 0.51 10.2 2.3 1.4 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor zf-C2H2_jaz PF12171.8 KXG50725.1 - 0.33 11.3 3.8 0.78 10.1 3.8 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Actin PF00022.19 KXG50726.1 - 7.1e-22 77.6 0.0 4e-18 65.2 0.0 3.1 3 0 0 3 3 3 3 Actin CBFD_NFYB_HMF PF00808.23 KXG50727.1 - 7.9e-18 64.5 0.3 7.9e-18 64.5 0.3 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXG50727.1 - 5.1e-08 33.4 1.1 1.5e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KXG50727.1 - 0.0082 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated DUF5333 PF17267.2 KXG50727.1 - 0.013 15.7 0.7 0.017 15.3 0.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5333) SPOB_ab PF14682.6 KXG50727.1 - 0.029 14.4 0.5 0.039 14.0 0.5 1.2 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal CENP-T_C PF15511.6 KXG50727.1 - 0.044 13.9 0.1 0.097 12.8 0.0 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 KXG50727.1 - 0.068 13.2 0.1 0.17 11.9 0.1 1.7 1 1 1 2 2 2 0 Transcription initiation factor IID, 31kD subunit YolD PF08863.10 KXG50727.1 - 0.43 10.7 7.2 0.4 10.8 5.5 1.7 2 0 0 2 2 2 0 YolD-like protein adh_short PF00106.25 KXG50728.1 - 3.9e-44 150.5 0.7 4.6e-44 150.2 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG50728.1 - 1.8e-30 106.2 0.2 2.2e-30 105.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG50728.1 - 1.5e-13 51.1 0.7 2.3e-13 50.4 0.7 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXG50728.1 - 0.00032 20.7 0.8 0.00047 20.1 0.8 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXG50728.1 - 0.0013 18.2 0.1 0.0052 16.3 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KXG50728.1 - 0.009 16.1 0.1 0.014 15.4 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KXG50728.1 - 0.043 14.4 0.0 0.12 13.0 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.10 KXG50728.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DAO PF01266.24 KXG50729.1 - 5.9e-43 147.8 0.0 6.8e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXG50729.1 - 6.1e-05 23.5 0.1 0.29 11.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG50729.1 - 0.002 17.4 0.0 0.73 9.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KXG50729.1 - 0.012 14.2 0.0 0.088 11.3 0.0 1.9 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.6 KXG50729.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain zf-CCCH PF00642.24 KXG50730.1 - 1.6e-07 31.0 17.4 2.5e-07 30.4 2.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXG50730.1 - 0.0049 16.9 3.3 0.0049 16.9 3.3 3.2 3 0 0 3 3 3 1 Zinc finger domain RRM_1 PF00076.22 KXG50730.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 KXG50730.1 - 0.047 13.9 2.2 0.13 12.4 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger containing family Torus PF16131.5 KXG50730.1 - 2.6 8.8 9.0 0.57 10.9 0.8 2.4 1 1 1 2 2 2 0 Torus domain SMC_Nse1 PF07574.13 KXG50731.1 - 5.8e-66 222.1 0.9 7.3e-66 221.8 0.9 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KXG50731.1 - 1.3e-13 51.0 11.9 2.2e-13 50.3 11.9 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 KXG50731.1 - 0.0062 16.8 8.5 0.01 16.1 8.5 1.4 1 0 0 1 1 1 1 Ring finger domain DUF4796 PF16044.5 KXG50731.1 - 0.0084 15.7 0.4 0.072 12.7 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4796) zf-ANAPC11 PF12861.7 KXG50731.1 - 0.015 15.4 2.2 0.025 14.6 2.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXG50731.1 - 0.18 11.5 6.7 0.29 10.8 6.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FYDLN_acid PF09538.10 KXG50731.1 - 0.93 10.2 4.5 0.37 11.5 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-HC5HC2H_2 PF13832.6 KXG50731.1 - 1.1 9.4 8.5 3.1 8.0 8.5 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KXG50731.1 - 1.3 9.3 10.1 4.7 7.5 10.2 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_2 PF13923.6 KXG50731.1 - 1.7 8.5 8.2 3 7.8 8.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KXG50731.1 - 2.3 8.5 6.6 7.7 6.8 6.6 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Glyco_hydro_65N PF03636.15 KXG50732.1 - 1.8e-33 116.1 0.0 5.5e-33 114.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 KXG50732.1 - 6.4e-24 84.5 2.1 5.5e-18 65.0 0.7 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 KXG50732.1 - 0.00032 20.6 0.1 0.00084 19.2 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Catalase PF00199.19 KXG50733.1 - 2.4e-164 547.0 0.0 3e-164 546.7 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 KXG50733.1 - 2.6e-49 166.8 0.2 4.2e-49 166.1 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 KXG50733.1 - 9.5e-17 61.0 0.1 2.3e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Acetyltransf_1 PF00583.25 KXG50734.1 - 1.7e-08 34.7 0.0 2.4e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXG50734.1 - 3.4e-06 27.4 0.0 5.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXG50734.1 - 1.6e-05 24.8 0.0 2.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXG50734.1 - 0.08 13.0 0.1 1.9 8.6 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Cupin_2 PF07883.11 KXG50735.1 - 9.8e-08 31.6 0.1 0.00063 19.4 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Na_Ca_ex PF01699.24 KXG50736.1 - 3.8e-32 111.3 38.6 4.9e-16 59.0 14.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Epimerase PF01370.21 KXG50737.1 - 1.4e-16 60.7 0.0 3.1e-16 59.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXG50737.1 - 7.1e-14 51.5 0.0 1.1e-13 50.8 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXG50737.1 - 7.2e-12 45.6 0.0 6.3e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXG50737.1 - 1.7e-10 40.5 0.0 3.8e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KXG50737.1 - 3.4e-07 30.1 0.2 1.1e-06 28.4 0.3 1.7 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KXG50737.1 - 4.3e-07 29.6 0.0 7.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXG50737.1 - 0.00016 20.9 0.0 0.00023 20.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KXG50737.1 - 0.00033 20.2 0.0 0.00097 18.6 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KXG50737.1 - 0.0068 16.3 0.7 0.09 12.7 0.7 2.1 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KXG50737.1 - 0.12 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Pyridoxal_deC PF00282.19 KXG50738.1 - 1.8e-99 333.0 0.0 2.1e-99 332.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KXG50738.1 - 0.0021 17.4 0.0 0.0052 16.1 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase SUKH_6 PF14568.6 KXG50738.1 - 0.069 13.6 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Cupin_2 PF07883.11 KXG50739.1 - 8.7e-05 22.2 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_2 PF07883.11 KXG50740.1 - 3.7e-08 33.0 0.0 6.5e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain SIR2 PF02146.17 KXG50741.1 - 7.1e-50 169.4 0.0 1.1e-49 168.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family KH_dom-like PF14714.6 KXG50741.1 - 0.026 14.8 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal TPP_enzyme_M PF00205.22 KXG50741.1 - 0.17 11.6 0.0 0.59 9.9 0.0 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Zn_clus PF00172.18 KXG50742.1 - 1.6e-08 34.5 10.6 3.1e-08 33.6 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXG50742.1 - 0.0011 18.1 0.5 0.0018 17.4 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXG50743.1 - 8.6e-28 97.3 46.3 2.3e-24 86.0 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_32C PF08244.12 KXG50744.1 - 1.9e-23 83.2 3.0 2.8e-23 82.7 3.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 KXG50744.1 - 4.6e-16 59.3 0.0 7.9e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Poxvirus_B22R PF04395.12 KXG50745.1 - 0.049 13.2 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 Poxvirus B22R protein p450 PF00067.22 KXG50746.1 - 3e-46 158.1 0.0 4e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S28 PF05577.12 KXG50747.1 - 6.9e-57 193.2 6.5 1.9e-56 191.7 5.9 1.8 2 1 0 2 2 2 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 KXG50747.1 - 0.066 11.9 0.8 0.21 10.2 0.8 1.8 1 1 0 1 1 1 0 PS-10 peptidase S37 NAD_binding_10 PF13460.6 KXG50748.1 - 5.4e-06 26.4 0.0 7e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXG50748.1 - 0.0023 17.2 0.0 0.0035 16.6 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KXG50748.1 - 0.0058 16.1 0.0 0.0076 15.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXG50748.1 - 0.049 14.1 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KXG50748.1 - 0.065 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 KXG50748.1 - 0.2 10.8 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RhgB_N PF09284.10 KXG50749.1 - 4.1e-109 363.9 5.0 4.1e-109 363.9 5.0 1.6 2 0 0 2 2 2 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KXG50749.1 - 8.9e-43 146.0 0.0 2.4e-42 144.6 0.0 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KXG50749.1 - 3.8e-23 81.1 9.1 3.8e-23 81.1 9.1 3.1 4 1 0 4 4 4 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KXG50749.1 - 0.00019 21.6 1.3 0.00019 21.6 1.3 4.1 5 0 0 5 5 5 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KXG50749.1 - 0.0096 15.9 0.1 0.037 14.0 0.1 2.0 1 0 0 1 1 1 1 CarboxypepD_reg-like domain DUF5011 PF16403.5 KXG50749.1 - 2.1 8.5 5.6 2.5 8.3 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) Amidohydro_1 PF01979.20 KXG50750.1 - 4.3e-63 213.7 0.0 7.9e-63 212.8 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXG50750.1 - 7.8e-06 25.6 0.3 0.0019 17.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF5111 PF17138.4 KXG50750.1 - 0.076 12.9 0.4 0.15 11.9 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5111) GDC-P PF02347.16 KXG50751.1 - 3.3e-174 579.7 0.0 2.5e-162 540.6 0.0 2.3 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KXG50751.1 - 0.00082 18.7 0.2 0.0017 17.7 0.2 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase MFS_1 PF07690.16 KXG50752.1 - 1.9e-33 115.9 33.2 1.9e-33 115.9 33.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KXG50753.1 - 1.3e-16 60.4 12.3 1.3e-16 60.4 12.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG50753.1 - 1.3e-09 37.4 0.6 1.3e-09 37.4 0.6 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter DUF5305 PF17231.2 KXG50753.1 - 0.053 12.9 0.1 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5305) MFS_1 PF07690.16 KXG50754.1 - 1.8e-42 145.5 53.0 1.8e-42 145.5 53.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG50754.1 - 2.6e-11 43.1 6.3 2.6e-11 43.1 6.3 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter DUF5305 PF17231.2 KXG50754.1 - 0.18 11.2 1.2 0.69 9.3 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5305) SnoaL_2 PF12680.7 KXG50755.1 - 0.00036 21.1 0.0 0.0017 18.9 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 KXG50755.1 - 0.0049 16.7 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.18 KXG50755.1 - 0.039 13.5 0.0 0.1 12.2 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family YrhK PF14145.6 KXG50756.1 - 0.23 11.4 21.7 9.8 6.1 3.6 4.2 3 2 0 3 3 3 0 YrhK-like protein Glyco_hydro_12 PF01670.16 KXG50757.1 - 3.2e-76 256.0 11.4 3.7e-76 255.8 11.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Glyco_hydro_16 PF00722.21 KXG50759.1 - 2.5e-07 30.3 0.0 7.8e-07 28.7 0.0 1.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KXG50759.1 - 0.037 12.4 0.2 0.25 9.7 0.1 1.9 1 1 1 2 2 2 0 Beta-glucan synthesis-associated protein (SKN1) MFS_1 PF07690.16 KXG50760.1 - 3e-32 111.9 89.9 4.1e-29 101.6 64.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily YrhC PF14143.6 KXG50760.1 - 0.17 12.0 0.2 0.17 12.0 0.2 3.6 3 1 2 5 5 5 0 YrhC-like protein Zn_clus PF00172.18 KXG50761.1 - 0.00046 20.3 15.7 0.00083 19.4 15.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDH-cyt PF16010.5 KXG50761.1 - 0.041 13.6 0.1 0.08 12.6 0.1 1.3 1 0 0 1 1 1 0 Cytochrome domain of cellobiose dehydrogenase Peptidase_M4_C PF02868.15 KXG50762.1 - 1.1e-38 132.8 0.0 1.8e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 KXG50762.1 - 4.7e-24 85.5 0.4 7.4e-24 84.9 0.4 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain PLN_propep PF16485.5 KXG50762.1 - 3.3e-08 33.1 0.1 6e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 Protealysin propeptide Ank_2 PF12796.7 KXG50763.1 - 1.5e-55 185.7 1.4 1.5e-10 41.5 0.3 5.9 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG50763.1 - 1.8e-46 155.9 5.3 5.8e-10 39.5 0.0 8.6 5 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG50763.1 - 1.5e-41 135.6 5.8 0.00021 21.5 0.0 11.4 11 1 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 KXG50763.1 - 2.4e-40 136.0 6.1 2.6e-06 27.6 0.0 9.7 4 3 7 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 KXG50763.1 - 8.1e-30 102.0 5.2 0.015 15.7 0.0 12.1 12 0 0 12 12 12 7 Ankyrin repeat Cas9_C PF18525.1 KXG50763.1 - 0.01 16.0 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Cas9 C-terminal domain DUF3435 PF11917.8 KXG50765.1 - 2.1e-22 79.7 0.0 3.8e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Tim54 PF11711.8 KXG50766.1 - 4.5e-152 506.2 1.1 5.2e-152 506.0 1.1 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.8 KXG50767.1 - 6.6e-217 721.5 17.7 2.9e-214 712.8 11.9 2.1 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 KXG50767.1 - 8.3e-18 63.0 27.4 0.00043 20.2 0.2 10.9 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXG50767.1 - 1.3e-17 64.0 22.3 0.0065 17.0 0.9 7.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.6 KXG50767.1 - 1.6e-16 59.5 21.6 0.026 15.3 0.2 11.4 8 3 4 12 12 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXG50767.1 - 8.1e-12 45.6 24.2 0.0032 18.1 0.6 8.2 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KXG50767.1 - 1.3e-07 31.2 13.6 0.00024 20.7 0.1 6.0 7 0 0 7 7 7 2 TPR repeat TPR_1 PF00515.28 KXG50767.1 - 1.6e-07 30.9 31.4 0.00011 21.8 0.2 9.6 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXG50767.1 - 3.1e-07 30.1 25.9 0.001 19.1 0.1 9.4 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXG50767.1 - 1.5e-06 28.1 12.9 0.74 10.3 0.1 7.5 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXG50767.1 - 3.5e-06 27.2 23.4 0.31 11.4 0.3 7.7 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXG50767.1 - 5.3e-06 26.5 10.7 0.0049 17.0 2.0 4.7 6 1 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG50767.1 - 0.00023 21.3 18.7 0.002 18.3 1.0 5.8 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KXG50767.1 - 0.0015 17.8 1.3 0.0015 17.8 1.3 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXG50767.1 - 0.012 15.6 6.6 10 6.2 0.0 5.2 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF3087 PF11286.8 KXG50767.1 - 0.016 14.7 2.3 0.45 10.0 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) FXR_C3 PF16097.5 KXG50767.1 - 0.067 13.9 3.2 0.42 11.3 0.0 2.5 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 TPR_6 PF13174.6 KXG50767.1 - 0.13 13.0 16.8 9.6 7.1 0.2 7.2 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXG50767.1 - 0.36 11.6 13.1 0.17 12.6 0.7 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 KXG50767.1 - 0.47 10.5 3.7 0.58 10.2 0.0 3.1 4 0 0 4 4 3 0 Tetratricopeptide repeat MIT PF04212.18 KXG50767.1 - 1.9 8.6 15.1 3 8.0 0.2 5.9 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Fapy_DNA_glyco PF01149.24 KXG50768.1 - 6.2e-35 120.3 0.0 1.7e-34 118.9 0.0 1.7 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KXG50768.1 - 2.8e-22 78.5 0.0 5.6e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KXG50768.1 - 0.0076 15.1 0.0 0.016 14.0 0.0 1.5 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) EIIBC-GUT_N PF03612.14 KXG50768.1 - 0.29 10.9 3.9 0.53 10.0 3.9 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2263 PF10021.9 KXG50769.1 - 3.2e-19 69.8 0.0 1.3e-18 67.7 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) NRDE-2 PF08424.10 KXG50769.1 - 0.023 13.8 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Macro PF01661.21 KXG50769.1 - 0.041 13.9 0.0 0.31 11.1 0.0 2.3 2 1 1 3 3 3 0 Macro domain Fe_hyd_lg_C PF02906.14 KXG50770.1 - 6.7e-50 170.0 0.0 1.3e-49 169.1 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DNA_RNApol_7kD PF03604.13 KXG50771.1 - 4.5e-17 61.4 5.7 5.8e-17 61.1 5.7 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 KXG50771.1 - 0.00099 19.1 0.1 0.0011 19.0 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2197 PF09963.9 KXG50771.1 - 0.0015 18.7 0.8 0.14 12.4 0.0 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2197) zf_UBZ PF18439.1 KXG50771.1 - 0.0015 18.1 0.8 1.1 8.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KXG50771.1 - 0.013 15.5 0.3 0.019 15.0 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_13 PF09855.9 KXG50771.1 - 0.017 15.2 0.2 0.28 11.4 0.0 2.1 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zinc-ribbon_6 PF10005.9 KXG50771.1 - 0.032 14.9 0.2 0.042 14.5 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KXG50771.1 - 0.49 10.6 3.5 3.6 7.8 3.6 2.0 1 1 2 3 3 3 0 Zinc ribbon domain Glycos_transf_3 PF00591.21 KXG50772.1 - 1.8e-56 191.6 0.0 1.2e-46 159.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KXG50772.1 - 4.1e-09 36.1 0.3 8.5e-09 35.1 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Ribosomal_L10 PF00466.20 KXG50773.1 - 0.011 15.8 0.0 0.27 11.4 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L10 PI-PLC-X PF00388.19 KXG50774.1 - 3.1e-08 33.3 0.0 1.2e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain 2-oxoacid_dh PF00198.23 KXG50775.1 - 4.6e-79 265.2 0.1 6.3e-79 264.7 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXG50775.1 - 5.7e-14 51.7 0.0 1.2e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KXG50775.1 - 1.8e-11 44.2 2.3 4e-11 43.1 0.2 2.5 2 0 0 2 2 2 1 e3 binding domain SKI PF01202.22 KXG50776.1 - 2e-10 41.0 0.0 3.5e-10 40.2 0.0 1.4 1 1 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 KXG50776.1 - 1.6e-08 34.8 0.0 2.2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXG50776.1 - 4.7e-07 30.4 0.1 7e-06 26.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 KXG50776.1 - 1.9e-05 24.7 0.0 0.07 13.0 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase Rad17 PF03215.15 KXG50776.1 - 9.9e-05 22.3 0.0 0.0002 21.4 0.0 1.5 2 0 0 2 2 2 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 KXG50776.1 - 0.00015 21.6 0.0 0.00051 19.8 0.0 1.7 2 0 0 2 2 2 1 Cytidylate kinase AAA_17 PF13207.6 KXG50776.1 - 0.00032 21.2 0.0 0.0016 18.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXG50776.1 - 0.012 16.0 0.1 0.023 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KXG50776.1 - 0.017 15.5 0.1 0.086 13.3 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXG50776.1 - 0.022 15.0 0.2 0.053 13.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain CoaE PF01121.20 KXG50776.1 - 0.032 13.9 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase ABC_tran PF00005.27 KXG50776.1 - 0.036 14.6 0.2 0.063 13.8 0.2 1.8 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 KXG50776.1 - 0.04 14.3 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 KXG50776.1 - 0.06 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase RuvB_N PF05496.12 KXG50776.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 KXG50776.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 KXG50776.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Vps26 PF03643.15 KXG50777.1 - 5.2e-129 429.1 0.2 6.4e-129 428.8 0.2 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KXG50777.1 - 0.00021 21.3 0.1 0.59 10.2 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KXG50777.1 - 0.0072 16.8 0.1 0.1 13.0 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Sec7_N PF12783.7 KXG50778.1 - 1.8e-42 144.9 6.2 5.9e-41 140.0 0.1 4.4 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KXG50778.1 - 3.7e-41 140.7 3.5 1.3e-40 138.9 3.5 2.0 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 KXG50778.1 - 3.5e-20 71.8 2.4 5.2e-20 71.2 1.0 1.9 2 0 0 2 2 2 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 KXG50778.1 - 0.0052 16.6 0.0 0.84 9.5 0.0 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Ipi1_N PF12333.8 KXG50778.1 - 2 9.0 6.8 24 5.6 0.1 5.0 5 0 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation UQ_con PF00179.26 KXG50779.1 - 6.3e-17 61.5 0.0 7.4e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXG50779.1 - 0.047 14.0 0.0 0.05 13.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain Complex1_LYR PF05347.15 KXG50780.1 - 1.1e-12 47.7 0.5 4.5e-12 45.8 0.1 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXG50780.1 - 0.021 15.5 0.4 0.046 14.5 0.3 1.7 1 1 0 1 1 1 0 Complex1_LYR-like RWD PF05773.22 KXG50781.1 - 5.1e-24 84.8 0.8 5.1e-24 84.8 0.8 1.6 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 KXG50781.1 - 2.3e-05 24.8 14.7 9.8e-05 22.8 14.6 2.1 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 TPR_2 PF07719.17 KXG50782.1 - 1.6e-09 37.2 1.1 0.01 15.9 0.0 5.7 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXG50782.1 - 8.6e-09 35.6 6.0 2e-07 31.2 0.5 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXG50782.1 - 9.3e-09 34.8 0.0 0.0018 18.3 0.0 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXG50782.1 - 2.5e-07 31.2 4.9 0.0037 17.9 0.6 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXG50782.1 - 3.7e-07 30.5 9.8 0.0027 18.2 2.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXG50782.1 - 8.3e-07 28.7 6.7 2.5e-06 27.1 0.3 2.8 2 1 0 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 KXG50782.1 - 6e-06 26.7 12.4 0.026 15.3 1.2 5.8 5 2 2 7 7 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXG50782.1 - 6.6e-06 25.7 0.6 0.04 13.6 0.0 3.5 5 0 0 5 5 5 2 TPR repeat TPR_1 PF00515.28 KXG50782.1 - 0.00014 21.5 0.2 0.063 13.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXG50782.1 - 0.00035 20.9 2.9 0.012 16.2 0.4 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXG50782.1 - 0.00095 19.0 2.2 3.2 8.0 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG50782.1 - 0.0025 18.0 0.0 2.9 8.2 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KXG50782.1 - 0.0042 17.4 0.0 1.6e+02 3.1 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXG50782.1 - 0.0057 16.8 9.2 1.9 8.7 0.6 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat Vps39_1 PF10366.9 KXG50782.1 - 0.016 15.5 0.8 0.11 12.8 0.2 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_10 PF13374.6 KXG50782.1 - 0.019 14.9 2.9 0.77 9.7 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 KXG50782.1 - 0.052 12.6 0.5 4.8 6.1 0.1 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 KXG50782.1 - 0.083 13.6 7.9 48 4.9 0.5 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 KXG50782.1 - 0.13 11.9 2.0 0.36 10.5 0.1 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain SIR2 PF02146.17 KXG50783.1 - 1.4e-58 197.7 0.0 2.3e-58 197.0 0.0 1.4 1 0 0 1 1 1 1 Sir2 family UPF0020 PF01170.18 KXG50783.1 - 5.1e-07 29.6 0.1 0.00012 21.8 0.1 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 TPP_enzyme_M PF00205.22 KXG50783.1 - 0.0025 17.6 0.0 0.69 9.7 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 KXG50783.1 - 0.0092 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) HIT PF01230.23 KXG50784.1 - 5.7e-17 62.3 0.7 2.9e-16 60.0 0.4 1.9 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 KXG50784.1 - 9.1e-05 22.9 0.0 0.00015 22.3 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KXG50784.1 - 0.0046 16.8 0.1 0.019 14.8 0.1 1.9 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Cyclin_N PF00134.23 KXG50785.1 - 1.3e-45 154.2 0.1 7.6e-45 151.8 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXG50785.1 - 9.5e-36 122.5 0.1 1.6e-35 121.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_L2_C PF03947.18 KXG50786.1 - 1e-50 171.1 3.8 4.5e-50 169.1 1.0 2.9 2 2 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KXG50786.1 - 1.2e-23 82.8 0.2 2.2e-23 82.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PAS PF00989.25 KXG50786.1 - 0.14 12.2 0.2 0.35 10.9 0.1 1.7 2 0 0 2 2 2 0 PAS fold Fungal_trans PF04082.18 KXG50787.1 - 1.2e-19 70.5 0.0 2.8e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG50787.1 - 1.4e-09 37.9 9.8 2.8e-09 36.9 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KXG50788.1 - 1.9e-23 82.3 10.4 1e-06 29.3 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG50788.1 - 2.3e-16 59.9 0.0 0.0044 17.3 0.0 6.1 2 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KXG50788.1 - 3.6e-09 35.6 0.0 4.2e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 KXG50788.1 - 7.7e-05 22.7 0.0 0.14 12.0 0.0 3.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 KXG50788.1 - 0.021 13.8 0.3 0.044 12.7 0.0 1.6 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 KXG50788.1 - 0.032 12.9 0.2 0.39 9.3 0.1 2.0 1 1 0 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.12 KXG50788.1 - 0.077 13.0 5.1 18 5.4 0.1 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat VID27 PF08553.10 KXG50788.1 - 0.13 11.3 0.0 0.69 8.9 0.0 1.9 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Ribonuc_P_40 PF08584.11 KXG50789.1 - 2.1e-70 237.2 0.0 2.1e-70 237.2 0.0 3.0 2 1 1 3 3 3 1 Ribonuclease P 40kDa (Rpp40) subunit Dna2 PF08696.11 KXG50790.1 - 1.3e-66 224.3 0.1 2.8e-66 223.2 0.1 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KXG50790.1 - 2.1e-52 177.7 0.0 3.1e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXG50790.1 - 3.4e-32 112.3 0.3 1.1e-15 58.1 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 KXG50790.1 - 5.4e-15 55.6 0.0 1.2e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXG50790.1 - 4e-12 46.7 0.1 9.6e-12 45.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 KXG50790.1 - 8.9e-08 32.3 0.1 1.8e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 KXG50790.1 - 4.6e-07 30.1 0.1 9.8e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 KXG50790.1 - 1.6e-05 24.7 0.3 0.44 10.3 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KXG50790.1 - 0.00013 21.9 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KXG50790.1 - 0.00016 21.3 0.1 0.00031 20.4 0.1 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 KXG50790.1 - 0.0019 17.9 1.0 0.0034 17.0 0.2 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Csa1 PF06023.12 KXG50790.1 - 0.0032 16.9 0.0 0.0093 15.3 0.0 1.7 1 1 0 1 1 1 1 CRISPR-associated exonuclease Csa1 PIF1 PF05970.14 KXG50790.1 - 0.0041 16.3 0.1 0.02 14.0 0.1 2.1 1 1 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 KXG50790.1 - 0.0045 17.4 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 KXG50790.1 - 0.011 15.8 0.4 0.036 14.1 0.4 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 KXG50790.1 - 0.011 15.0 0.1 0.15 11.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.14 KXG50790.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 KXG50790.1 - 0.033 13.7 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 KXG50790.1 - 0.039 14.0 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KXG50790.1 - 0.046 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KXG50790.1 - 0.067 13.3 0.2 0.18 11.9 0.2 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_18 PF13238.6 KXG50790.1 - 0.12 12.9 0.0 0.4 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KXG50790.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ZoocinA_TRD PF16775.5 KXG50790.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Target recognition domain of lytic exoenzyme AAA_22 PF13401.6 KXG50790.1 - 0.16 12.2 0.6 1.6 9.0 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KXG50790.1 - 0.16 12.4 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXG50790.1 - 0.16 12.1 0.3 0.77 9.9 0.1 2.2 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.15 KXG50790.1 - 0.2 11.5 0.2 0.61 10.0 0.2 1.7 1 0 0 1 1 1 0 NTPase ESSS PF10183.9 KXG50791.1 - 1.5e-18 66.9 0.0 1.8e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CN_hydrolase PF00795.22 KXG50792.1 - 7.4e-52 176.3 0.0 9e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RNB PF00773.19 KXG50793.1 - 1.2e-99 333.8 0.1 2.6e-99 332.7 0.0 1.6 2 0 0 2 2 2 1 RNB domain Rrp44_S1 PF17215.3 KXG50793.1 - 1.2e-29 102.1 0.8 1.2e-29 102.1 0.8 2.1 2 0 0 2 2 2 1 S1 domain Rrp44_CSD1 PF17216.3 KXG50793.1 - 4.6e-29 101.0 0.0 1.4e-28 99.4 0.0 1.8 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 KXG50793.1 - 8.6e-21 73.8 0.0 2.2e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KXG50793.1 - 1.3e-08 34.8 0.0 1.3e-05 25.3 0.0 3.0 3 0 0 3 3 3 2 Cold shock domain PIN_4 PF13638.6 KXG50793.1 - 2.5e-07 31.0 0.0 6.3e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 PIN domain MFS_1 PF07690.16 KXG50794.1 - 3.7e-24 85.3 44.3 3.7e-24 85.3 44.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily LIM PF00412.22 KXG50795.1 - 3.2e-26 91.3 26.5 2.3e-10 40.5 3.6 3.9 3 1 0 3 3 3 3 LIM domain Zn_ribbon_recom PF13408.6 KXG50795.1 - 0.072 13.6 1.4 0.2 12.2 0.1 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Methyltransf_4 PF02390.17 KXG50796.1 - 1.6e-45 154.7 0.8 2.6e-32 111.7 0.4 3.1 1 1 1 2 2 2 2 Putative methyltransferase MTS PF05175.14 KXG50796.1 - 0.0013 18.3 0.0 0.037 13.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KXG50796.1 - 0.0018 18.9 0.1 0.012 16.3 0.0 2.4 2 1 0 3 3 3 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXG50796.1 - 0.0033 17.4 0.0 0.0053 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG50796.1 - 0.027 15.2 0.0 0.079 13.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF913 PF06025.12 KXG50796.1 - 0.03 13.3 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Methyltransf_31 PF13847.6 KXG50796.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.11 KXG50796.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) ESCRT-II PF05871.12 KXG50797.1 - 1.5e-51 174.4 0.0 1.8e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit RTT107_BRCT_5 PF16770.5 KXG50798.1 - 2.3e-35 120.4 0.5 3.4e-31 107.1 0.0 4.8 6 0 0 6 6 6 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KXG50798.1 - 1.8e-33 114.3 1.5 9.2e-20 70.4 0.5 6.0 6 1 0 6 6 6 4 twin BRCT domain BRCT PF00533.26 KXG50798.1 - 1.2e-27 96.0 0.0 5.1e-08 33.2 0.0 6.7 6 1 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXG50798.1 - 3.5e-24 85.0 0.0 0.00027 21.3 0.0 6.4 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KXG50798.1 - 2.8e-09 37.2 0.0 0.0047 17.2 0.0 4.1 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KXG50798.1 - 5.7e-05 23.1 0.0 2.5 8.2 0.0 4.8 6 0 0 6 6 6 2 BRCA1 C Terminus (BRCT) domain Sox17_18_mid PF12067.8 KXG50798.1 - 0.024 14.7 1.3 1.1 9.4 0.2 2.8 3 0 0 3 3 3 0 Sox 17/18 central domain zf-C2H2_4 PF13894.6 KXG50799.1 - 0.051 14.4 0.1 0.14 13.1 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger HNH_2 PF13391.6 KXG50800.1 - 3.6e-15 55.9 0.1 7.2e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease Sulfate_transp PF00916.20 KXG50801.1 - 4.9e-64 216.4 25.9 7e-64 215.9 25.9 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KXG50801.1 - 9.9e-15 54.4 0.0 1.8e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KXG50801.1 - 4.4e-11 42.4 0.0 9.2e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 STAS domain Sld5 PF05916.11 KXG50802.1 - 8.7e-13 48.7 0.0 1.4e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein FliT PF05400.13 KXG50802.1 - 0.037 14.8 0.0 0.39 11.6 0.0 2.6 3 0 0 3 3 3 0 Flagellar protein FliT DIOX_N PF14226.6 KXG50803.1 - 1.4e-29 103.3 0.0 2.2e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG50803.1 - 2.9e-11 43.7 0.0 6.9e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PRP4 PF08799.11 KXG50805.1 - 0.47 10.1 3.1 17 5.0 1.2 3.3 3 0 0 3 3 3 0 pre-mRNA processing factor 4 (PRP4) like DUF4690 PF15756.5 KXG50807.1 - 0.038 14.6 1.5 0.038 14.6 1.5 2.6 3 0 0 3 3 3 0 Small Novel Rich in Cartilage DUF202 PF02656.15 KXG50807.1 - 0.64 10.5 2.6 8.2 7.0 2.6 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Insulin_TMD PF17870.1 KXG50807.1 - 4.7 7.3 5.6 0.94 9.6 1.5 1.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Rcd1 PF04078.13 KXG50808.1 - 3.9e-126 419.6 2.3 4.7e-126 419.4 2.3 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TFIIA PF03153.13 KXG50808.1 - 1.8 8.4 13.8 2.2 8.2 13.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ARS2 PF04959.13 KXG50808.1 - 9.8 6.5 10.7 16 5.8 10.7 1.2 1 0 0 1 1 1 0 Arsenite-resistance protein 2 PHD PF00628.29 KXG50809.1 - 5.9e-09 35.7 9.7 1.7e-08 34.2 9.7 1.8 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXG50809.1 - 0.0047 16.5 5.9 0.0047 16.5 5.9 1.9 2 0 0 2 2 2 1 PHD-finger DUF1524 PF07510.11 KXG50809.1 - 0.0073 16.2 3.0 0.013 15.3 0.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1524) C1_2 PF03107.16 KXG50809.1 - 7.1 7.0 6.6 1.4 9.3 1.9 2.1 2 0 0 2 2 2 0 C1 domain HMG_box PF00505.19 KXG50810.1 - 1.9e-10 41.0 0.1 4.5e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXG50810.1 - 0.012 16.2 0.5 0.037 14.6 0.5 1.9 1 0 0 1 1 1 0 HMG-box domain Prefoldin_2 PF01920.20 KXG50811.1 - 7.2e-19 67.7 4.0 8.9e-19 67.4 4.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit T6PP_N PF18572.1 KXG50811.1 - 0.31 10.9 4.0 1 9.2 4.0 1.8 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain CENP-H PF05837.12 KXG50811.1 - 0.96 9.9 6.7 4.5 7.7 0.4 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4200 PF13863.6 KXG50811.1 - 1.5 9.3 9.4 0.71 10.3 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Mito_carr PF00153.27 KXG50813.1 - 2.5e-52 174.8 3.4 3.5e-18 65.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ceramidase PF05875.12 KXG50814.1 - 1.2e-103 346.1 7.5 1.4e-103 345.9 7.5 1.0 1 0 0 1 1 1 1 Ceramidase Abhydrolase_6 PF12697.7 KXG50815.1 - 2.3e-14 54.5 1.2 4e-14 53.7 1.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG50815.1 - 4.5e-07 29.4 0.0 6.7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXG50815.1 - 2e-05 24.4 0.0 3.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KXG50815.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein VPS9 PF02204.18 KXG50816.1 - 1.1e-29 102.7 0.0 2.3e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KXG50816.1 - 3.2e-15 56.2 0.6 7.9e-15 54.9 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KXG50816.1 - 4.9e-10 38.9 0.5 1e-08 34.7 0.0 2.4 2 0 0 2 2 2 1 CUE domain Asn_synthase PF00733.21 KXG50817.1 - 5.9e-14 52.5 0.3 4.2e-06 26.7 0.0 3.1 2 1 1 3 3 3 2 Asparagine synthase GATase_7 PF13537.6 KXG50817.1 - 1.9e-06 27.8 0.0 7.4e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXG50817.1 - 0.00072 19.1 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Aluminium induced protein GATase_6 PF13522.6 KXG50817.1 - 0.0055 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain bZIP_2 PF07716.15 KXG50818.1 - 0.00015 21.8 7.6 0.0003 20.8 7.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper PKcGMP_CC PF16808.5 KXG50818.1 - 0.00051 19.8 4.0 0.0009 19.0 4.0 1.3 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase XLF PF09302.11 KXG50818.1 - 0.051 13.7 0.5 0.091 12.9 0.5 1.3 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component bZIP_1 PF00170.21 KXG50818.1 - 0.15 12.1 7.8 0.3 11.2 7.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor SlyX PF04102.12 KXG50818.1 - 0.19 12.4 1.6 0.4 11.3 1.6 1.5 1 0 0 1 1 1 0 SlyX MFS_1 PF07690.16 KXG50819.1 - 6.8e-36 123.9 43.7 1.2e-35 123.1 42.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG50819.1 - 1.1e-09 37.7 8.7 1.1e-09 37.7 8.7 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter PetG PF02529.15 KXG50819.1 - 6 6.8 6.8 8.4 6.3 0.1 2.8 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 PH_6 PF15406.6 KXG50820.1 - 9.2e-38 129.0 3.1 9.2e-38 129.0 3.1 3.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KXG50820.1 - 6.4e-08 33.1 0.2 3.7e-07 30.6 0.0 2.4 2 1 0 2 2 2 1 PH domain PH_13 PF16652.5 KXG50820.1 - 0.11 12.2 0.1 0.11 12.2 0.1 2.2 3 0 0 3 3 3 0 Pleckstrin homology domain Ribosomal_L6 PF00347.23 KXG50820.1 - 0.23 12.2 2.2 0.85 10.3 0.4 2.7 2 0 0 2 2 2 0 Ribosomal protein L6 PH_4 PF15404.6 KXG50820.1 - 0.45 10.3 0.0 0.45 10.3 0.0 3.7 2 1 0 2 2 2 0 Pleckstrin homology domain Acetyltransf_3 PF13302.7 KXG50822.1 - 9.5e-29 100.8 0.0 1.2e-28 100.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG50822.1 - 0.0027 17.9 0.0 0.014 15.6 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family V_ATPase_I PF01496.19 KXG50823.1 - 0 1077.7 0.0 0 1077.5 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CheZ PF04344.13 KXG50823.1 - 0.014 15.3 2.0 0.068 13.1 0.2 2.3 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ DUF1515 PF07439.11 KXG50823.1 - 0.036 14.1 0.1 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DASH_Dam1 PF08653.10 KXG50823.1 - 0.14 12.0 0.8 9.2 6.2 0.0 3.6 4 0 0 4 4 4 0 DASH complex subunit Dam1 Filament PF00038.21 KXG50823.1 - 0.56 9.7 4.7 20 4.6 0.0 2.6 2 1 0 2 2 2 0 Intermediate filament protein Nup54 PF13874.6 KXG50823.1 - 0.62 10.2 2.0 1.5 8.9 0.4 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF2626 PF11117.8 KXG50823.1 - 1.4 9.7 8.1 5.5 7.8 8.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2626) Tektin PF03148.14 KXG50823.1 - 2.5 6.8 5.7 6.3 5.4 0.5 2.7 2 1 1 3 3 3 0 Tektin family FBPase PF00316.20 KXG50824.1 - 1.9e-66 223.2 0.0 2.6e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain MFS_1 PF07690.16 KXG50825.1 - 2.4e-38 132.0 42.4 8.4e-31 107.2 23.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG50825.1 - 4.9e-07 28.9 6.3 1.4e-06 27.4 3.5 2.7 1 1 2 3 3 3 1 MFS_1 like family LRR19-TM PF15176.6 KXG50825.1 - 0.07 13.1 0.2 13 5.8 0.0 3.1 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain Aha1_N PF09229.11 KXG50827.1 - 2.1e-41 141.3 2.5 4.8e-41 140.2 1.3 2.0 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KXG50827.1 - 2.9e-19 69.5 0.4 5e-19 68.8 0.4 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Sacchrp_dh_C PF16653.5 KXG50828.1 - 2.3e-92 309.9 0.0 4.1e-92 309.0 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KXG50828.1 - 2e-26 92.8 0.7 3.2e-26 92.1 0.7 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXG50828.1 - 1.1e-08 35.3 0.3 2.3e-08 34.2 0.3 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KXG50828.1 - 2.5e-06 27.5 0.5 8.5e-06 25.8 0.3 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KXG50828.1 - 0.00082 19.0 0.5 0.0013 18.3 0.5 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KXG50828.1 - 0.001 18.2 0.1 0.0014 17.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family IlvN PF07991.12 KXG50828.1 - 0.0014 18.2 0.2 0.011 15.3 0.1 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KXG50828.1 - 0.0079 16.7 0.2 0.016 15.7 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KXG50828.1 - 0.027 13.8 0.7 0.041 13.2 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KXG50828.1 - 0.068 13.6 0.3 0.16 12.5 0.3 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.25 KXG50828.1 - 0.088 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Prenyltransf PF01255.19 KXG50829.1 - 1.7e-80 269.7 0.0 3.1e-80 268.9 0.0 1.4 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Acyltransferase PF01553.21 KXG50831.1 - 2e-08 34.0 0.0 4e-07 29.7 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase ABC2_membrane_4 PF12730.7 KXG50831.1 - 0.015 15.3 6.7 0.42 10.5 0.5 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein UCR_hinge PF02320.16 KXG50832.1 - 1.7e-25 89.0 9.1 3.5e-25 88.0 9.1 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein RR_TM4-6 PF06459.12 KXG50832.1 - 0.15 11.9 14.2 0.22 11.3 14.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 KXG50832.1 - 0.27 10.6 18.9 0.45 9.9 18.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Spore_coat_CotO PF14153.6 KXG50832.1 - 0.37 10.7 17.7 0.64 9.9 17.7 1.4 1 0 0 1 1 1 0 Spore coat protein CotO SAPS PF04499.15 KXG50832.1 - 0.52 9.0 6.7 0.77 8.5 6.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 KXG50832.1 - 0.65 9.3 21.1 0.9 8.8 21.1 1.1 1 0 0 1 1 1 0 BUD22 Smg8_Smg9 PF10220.9 KXG50832.1 - 0.71 8.1 6.8 0.95 7.7 6.8 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Myc_N PF01056.18 KXG50832.1 - 0.87 9.4 16.0 1.4 8.8 16.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DUF913 PF06025.12 KXG50832.1 - 2.7 6.9 7.0 4.4 6.2 7.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4045 PF13254.6 KXG50832.1 - 4.1 7.0 15.7 6.2 6.3 15.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) MFS_1 PF07690.16 KXG50833.1 - 6.7e-20 71.3 31.3 5.1e-12 45.4 10.2 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG50833.1 - 1.6 7.5 10.4 0.021 13.7 2.2 2.0 2 1 0 2 2 2 0 MFS_1 like family Uds1 PF15456.6 KXG50834.1 - 1.7e-45 154.3 0.7 1.7e-45 154.3 0.7 7.7 5 3 1 6 6 6 1 Up-regulated During Septation DUF4460 PF14687.6 KXG50834.1 - 0.12 12.5 7.6 20 5.3 0.0 5.8 3 2 2 6 6 6 0 Domain of unknown function (DUF4460) HsbA PF12296.8 KXG50834.1 - 0.81 10.1 8.5 1.1 9.7 0.4 4.5 2 1 1 4 4 4 0 Hydrophobic surface binding protein A DUF4407 PF14362.6 KXG50834.1 - 0.84 8.9 86.1 0.015 14.7 17.3 5.9 2 1 4 6 6 6 0 Domain of unknown function (DUF4407) GIT_CC PF16559.5 KXG50834.1 - 1.7 8.6 40.3 1.4 8.9 0.5 10.3 7 2 5 12 12 12 0 GIT coiled-coil Rho guanine nucleotide exchange factor ApoO PF09769.9 KXG50834.1 - 3.2 7.7 19.8 11 6.0 0.2 6.1 2 1 4 6 6 6 0 Apolipoprotein O Fez1 PF06818.15 KXG50834.1 - 5.1 7.5 90.1 0.028 14.9 22.9 5.9 2 2 3 6 6 6 0 Fez1 GST_C_2 PF13410.6 KXG50836.1 - 3.9e-08 33.2 1.1 1.3e-07 31.5 1.2 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXG50836.1 - 5.9e-05 23.3 0.1 0.00024 21.3 0.1 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXG50836.1 - 0.00042 20.7 0.1 0.0014 19.0 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXG50836.1 - 0.00053 20.2 0.1 0.0013 18.9 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain WD40 PF00400.32 KXG50837.1 - 1.1e-29 102.0 16.8 5.1e-06 27.1 0.1 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat F-box-like PF12937.7 KXG50837.1 - 2.1e-10 40.3 1.5 4.7e-10 39.2 1.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXG50837.1 - 4.8e-08 32.7 0.3 9.2e-08 31.8 0.3 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KXG50837.1 - 1.8e-06 28.1 1.4 0.0042 17.4 0.1 3.4 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXG50837.1 - 8e-05 21.5 2.0 0.96 8.0 0.0 3.5 3 1 0 3 3 3 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KXG50837.1 - 0.052 12.9 0.1 5 6.3 0.1 2.8 2 1 1 3 3 3 0 WD40-like domain PH_10 PF15411.6 KXG50838.1 - 3.8e-40 137.0 0.0 8.8e-40 135.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 KXG50838.1 - 3.1e-34 117.1 0.0 6.1e-34 116.1 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 KXG50838.1 - 1.5e-25 90.5 2.1 2.7e-25 89.7 2.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 KXG50838.1 - 1.2e-08 34.7 0.1 2.9e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 PB1 domain Aminotran_1_2 PF00155.21 KXG50839.1 - 5.5e-34 117.9 0.0 7.2e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-C2H2 PF00096.26 KXG50840.1 - 1.5e-17 62.9 40.1 3.5e-05 24.0 5.0 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXG50840.1 - 6.2e-15 54.9 29.1 3.1e-05 24.2 0.7 4.8 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXG50840.1 - 6.3e-06 26.6 36.0 0.089 13.7 3.8 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KXG50840.1 - 0.13 12.5 13.7 0.69 10.3 1.2 3.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon TFIIA PF03153.13 KXG50840.1 - 4 7.3 18.8 4.6 7.1 18.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suc_Fer-like PF06999.12 KXG50841.1 - 1.2e-69 234.1 0.0 1.5e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF4129 PF13559.6 KXG50842.1 - 3.4e-05 24.0 0.1 9.7e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) NICE-3 PF07406.11 KXG50842.1 - 0.0012 18.9 0.1 0.051 13.6 0.0 2.1 2 0 0 2 2 2 2 NICE-3 protein adh_short PF00106.25 KXG50843.1 - 8e-10 38.5 0.0 1.9e-05 24.2 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXG50843.1 - 0.043 13.4 0.0 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG50843.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 KR domain NTP_transferase PF00483.23 KXG50844.1 - 6.2e-53 179.9 0.0 1.2e-52 179.0 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KXG50844.1 - 1.9e-14 52.7 11.2 6.3e-11 41.5 4.6 4.0 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KXG50844.1 - 7.2e-10 39.4 0.0 1.1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KXG50844.1 - 5.5e-06 26.0 3.0 5.5e-06 26.0 3.0 3.1 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KXG50844.1 - 0.0048 15.1 0.3 0.007 14.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.19 KXG50844.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Peptidase_M41 PF01434.18 KXG50846.1 - 1.1e-56 191.7 1.0 2.1e-56 190.8 0.6 1.7 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 KXG50846.1 - 3.6e-43 147.1 0.0 9.1e-43 145.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXG50846.1 - 1.2e-09 37.8 0.0 3.2e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXG50846.1 - 1.4e-05 25.1 0.0 4e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXG50846.1 - 2.5e-05 24.7 0.5 0.00044 20.7 0.5 2.7 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KXG50846.1 - 7.3e-05 22.1 3.5 0.00015 21.1 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 KXG50846.1 - 0.00033 20.9 0.2 0.026 14.8 0.2 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXG50846.1 - 0.00054 19.7 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KXG50846.1 - 0.005 17.0 0.0 0.014 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXG50846.1 - 0.0082 15.7 1.0 0.76 9.3 0.3 2.5 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXG50846.1 - 0.014 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KXG50846.1 - 0.016 15.7 0.0 0.094 13.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 KXG50846.1 - 0.023 14.8 0.0 0.079 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KXG50846.1 - 0.028 13.8 0.3 0.053 12.9 0.3 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KXG50846.1 - 0.096 12.9 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KXG50846.1 - 0.097 11.8 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase PF06745.13 KXG50846.1 - 0.1 11.9 0.7 1.5 8.1 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_17 PF13207.6 KXG50846.1 - 0.11 12.9 0.0 0.31 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXG50846.1 - 0.12 12.2 0.3 1.9 8.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KXG50846.1 - 0.19 11.3 0.1 0.47 9.9 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KXG50846.1 - 0.3 10.3 2.8 0.79 9.0 0.4 2.6 2 1 1 3 3 3 0 Zeta toxin FGGY_C PF02782.16 KXG50847.1 - 4.1e-73 245.3 1.7 7.4e-73 244.5 1.7 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXG50847.1 - 1.2e-61 208.4 0.0 1.7e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KXG50847.1 - 0.0088 15.6 0.3 2.2 7.7 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family DUF3429 PF11911.8 KXG50848.1 - 3.2e-43 147.5 13.3 4.6e-43 147.0 13.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) SHR-BD PF06650.12 KXG50849.1 - 7.5e-97 323.9 0.0 1.7e-95 319.5 0.0 3.0 2 1 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 KXG50849.1 - 8.8e-94 313.3 9.4 1.5e-88 296.2 0.5 5.5 5 0 0 5 5 5 2 Repeating coiled region of VPS13 VPS13 PF16908.5 KXG50849.1 - 1.1e-78 264.3 0.0 7.1e-77 258.4 0.0 3.4 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KXG50849.1 - 1.3e-74 249.8 4.4 2.5e-69 232.6 0.5 2.9 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KXG50849.1 - 1.1e-41 141.6 0.0 3.5e-41 140.0 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KXG50849.1 - 6.4e-07 29.6 0.0 2.5e-06 27.7 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain DUF3405 PF11885.8 KXG50850.1 - 5.9e-159 530.0 9.1 3.7e-156 520.8 9.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) BLM10_mid PF16507.5 KXG50851.1 - 6.1e-206 685.1 0.0 1.1e-205 684.3 0.0 1.4 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KXG50851.1 - 2.2e-29 101.2 0.0 1.2e-28 98.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 KXG50851.1 - 7e-20 71.1 0.0 2.1e-19 69.6 0.0 1.9 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal CLASP_N PF12348.8 KXG50851.1 - 2.8e-05 23.8 0.1 0.079 12.5 0.0 2.7 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 KXG50851.1 - 0.022 15.0 0.0 2.1 8.8 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat Aldo_ket_red PF00248.21 KXG50853.1 - 8.9e-72 241.7 0.0 1.1e-71 241.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FMO-like PF00743.19 KXG50854.1 - 5.4e-12 44.9 0.1 3.1e-10 39.1 0.2 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXG50854.1 - 6.4e-12 45.3 0.0 9.4e-10 38.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG50854.1 - 1.9e-10 40.8 0.1 7.1e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXG50854.1 - 2.9e-06 26.7 0.0 5.1e-05 22.7 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG50854.1 - 1.4e-05 24.4 0.1 0.0026 16.9 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXG50854.1 - 0.0017 18.4 1.3 0.02 14.8 0.0 3.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXG50854.1 - 0.0083 16.7 0.2 3.4 8.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG50854.1 - 0.07 12.7 0.1 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXG50854.1 - 0.076 12.3 0.6 0.83 8.9 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KXG50854.1 - 0.1 11.8 0.2 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 KXG50854.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Oxidored_FMN PF00724.20 KXG50856.1 - 8.4e-73 245.6 0.0 1.2e-72 245.1 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 KXG50856.1 - 0.084 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) DUF5510 PF17629.2 KXG50857.1 - 4.4 7.3 12.6 5.3 7.0 6.3 3.0 2 1 0 2 2 2 0 Family of unknown function (DUF5510) Fungal_trans PF04082.18 KXG50858.1 - 4.6e-17 61.9 3.2 4.6e-17 61.9 3.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Beta_elim_lyase PF01212.21 KXG50859.1 - 3.2e-36 125.1 0.0 3.7e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KXG50859.1 - 5.3e-07 29.1 0.0 8e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXG50859.1 - 6.7e-05 22.0 0.0 8.6e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.19 KXG50859.1 - 0.006 15.3 0.0 0.011 14.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Arylsulfotran_2 PF14269.6 KXG50860.1 - 2.6e-41 141.9 0.1 4.4e-41 141.2 0.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXG50860.1 - 3.8e-12 45.8 0.1 1.7e-10 40.4 0.1 2.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF1180 PF06679.12 KXG50860.1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) BSMAP PF12280.8 KXG50860.1 - 0.7 10.1 0.0 0.7 10.1 0.0 2.3 3 0 0 3 3 3 0 Brain specific membrane anchored protein Sulfatase PF00884.23 KXG50861.1 - 3.9e-15 56.0 0.8 6.7e-15 55.3 0.8 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXG50861.1 - 1.3e-05 24.9 0.1 1.9e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KXG50861.1 - 0.0027 16.4 0.9 0.0053 15.4 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 KXG50861.1 - 0.038 13.0 1.8 0.12 11.4 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1501) AAA PF00004.29 KXG50862.1 - 3.2e-15 56.7 0.0 7.2e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KXG50862.1 - 0.0032 17.6 0.0 0.015 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KXG50862.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXG50862.1 - 0.024 15.0 0.0 0.074 13.4 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KXG50862.1 - 0.026 14.5 0.0 0.074 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 KXG50862.1 - 0.041 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXG50862.1 - 0.084 13.2 0.2 0.46 10.7 0.0 2.2 1 1 1 2 2 2 0 AAA domain NAD_binding_4 PF07993.12 KXG50863.1 - 3.9e-73 245.8 0.0 5.8e-73 245.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXG50863.1 - 1.1e-66 225.2 0.0 1.9e-66 224.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Pro_CA PF00484.19 KXG50863.1 - 5e-42 143.8 0.0 1.1e-41 142.8 0.0 1.6 1 0 0 1 1 1 1 Carbonic anhydrase Epimerase PF01370.21 KXG50863.1 - 1.4e-11 44.4 0.0 4.5e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Condensation PF00668.20 KXG50863.1 - 2.7e-10 39.5 0.0 2.1e-09 36.6 0.0 2.0 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KXG50863.1 - 5e-07 30.0 0.0 1.3e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KXG50863.1 - 1.2e-06 27.8 0.0 2.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KXG50863.1 - 9e-05 23.4 0.0 0.00094 20.1 0.0 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.17 KXG50863.1 - 0.0024 17.0 0.0 0.09 11.9 0.0 2.4 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXG50863.1 - 0.0063 16.4 0.2 0.061 13.2 0.2 2.4 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXG50863.1 - 0.0064 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXG50863.1 - 0.039 13.4 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Ald_Xan_dh_C2 PF02738.18 KXG50865.1 - 6e-202 672.0 1.9 8.5e-202 671.4 1.9 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KXG50865.1 - 1.1e-47 162.0 0.0 2e-47 161.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 KXG50865.1 - 4.5e-32 110.3 0.1 1.7e-31 108.4 0.1 2.1 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 KXG50865.1 - 3.5e-31 107.8 0.0 7.7e-31 106.7 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 KXG50865.1 - 1.5e-29 101.8 0.0 3.2e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KXG50865.1 - 5e-07 29.6 2.2 5.5e-07 29.5 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Baculo_PEP_C PF04513.12 KXG50866.1 - 0.017 15.2 8.1 0.065 13.3 1.1 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dynamin_M PF01031.20 KXG50866.1 - 0.1 11.8 0.0 11 5.2 0.0 2.6 2 1 0 3 3 3 0 Dynamin central region YtxH PF12732.7 KXG50866.1 - 0.15 12.6 0.3 65 4.2 0.0 3.4 3 0 0 3 3 3 0 YtxH-like protein ETRAMP PF09716.10 KXG50866.1 - 0.27 11.3 2.0 49 4.1 0.3 3.7 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) ApoLp-III PF07464.11 KXG50866.1 - 1.4 9.0 6.1 1.8 8.6 1.2 3.1 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) zf-MYND PF01753.18 KXG50867.1 - 0.28 11.3 6.4 0.73 10.0 6.4 1.8 1 0 0 1 1 1 0 MYND finger FAM199X PF15814.5 KXG50867.1 - 2.2 7.2 14.3 0.021 13.9 6.2 1.7 2 0 0 2 2 2 0 Protein family FAM199X Aminotran_1_2 PF00155.21 KXG50868.1 - 2.2e-69 234.4 0.0 2.5e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXG50868.1 - 0.0019 16.8 0.0 0.0029 16.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KXG50868.1 - 0.0065 15.8 0.0 0.0096 15.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KXG50868.1 - 0.1 11.5 0.0 0.2 10.5 0.0 1.4 2 0 0 2 2 2 0 Aminotransferase class-V MgsA_C PF12002.8 KXG50869.1 - 4e-57 192.8 0.0 6.8e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KXG50869.1 - 3.9e-23 81.6 1.0 1e-22 80.3 0.3 2.0 2 0 0 2 2 2 1 AAA C-terminal domain AAA PF00004.29 KXG50869.1 - 1.1e-12 48.5 0.0 2.5e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXG50869.1 - 3.9e-09 36.5 0.0 7.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KXG50869.1 - 1.8e-05 24.2 0.0 0.14 11.6 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KXG50869.1 - 5.8e-05 22.9 0.0 0.0029 17.3 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KXG50869.1 - 7.8e-05 22.7 0.0 0.0013 18.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXG50869.1 - 0.00031 21.2 0.4 0.093 13.1 0.1 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_3 PF07726.11 KXG50869.1 - 0.0015 18.4 0.0 0.0059 16.5 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXG50869.1 - 0.0029 17.9 0.0 0.0088 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXG50869.1 - 0.0062 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.15 KXG50869.1 - 0.012 15.6 0.1 2.3 8.2 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KXG50869.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KXG50869.1 - 0.021 14.9 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 KXG50869.1 - 0.028 14.1 0.1 0.063 13.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 KXG50869.1 - 0.034 13.4 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain PIF1 PF05970.14 KXG50869.1 - 0.038 13.2 0.1 0.062 12.5 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_18 PF13238.6 KXG50869.1 - 0.09 13.3 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXG50869.1 - 0.093 12.5 0.1 5.6 6.8 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KXG50869.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXG50869.1 - 0.2 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Zn_clus PF00172.18 KXG50870.1 - 0.63 10.2 8.3 1.5 9.0 8.3 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain EF-hand_1 PF00036.32 KXG50871.1 - 2.6e-14 51.6 2.8 1.7e-05 24.0 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KXG50871.1 - 2.8e-14 53.3 3.1 6.8e-08 32.9 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXG50871.1 - 3.8e-13 48.2 3.6 1.7e-05 24.3 0.2 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KXG50871.1 - 1.6e-10 40.7 3.0 5.8e-08 32.5 0.1 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 KXG50871.1 - 0.038 13.9 0.0 0.096 12.7 0.0 1.7 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF3572 PF12096.8 KXG50871.1 - 0.04 14.1 0.1 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) EF-hand_5 PF13202.6 KXG50871.1 - 6.6 6.4 10.3 6.9 6.4 0.1 3.6 4 0 0 4 4 4 0 EF hand Reprolysin_5 PF13688.6 KXG50872.1 - 3.3e-61 206.9 9.6 4e-61 206.6 7.7 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KXG50872.1 - 2.2e-49 167.9 3.1 4.1e-49 167.0 3.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KXG50872.1 - 1.8e-42 145.5 3.5 5e-42 144.0 3.5 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like IMS PF00817.20 KXG50872.1 - 1.3e-35 122.7 0.0 2.1e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KXG50872.1 - 3.3e-18 66.5 0.1 1e-17 64.9 0.1 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain Disintegrin PF00200.23 KXG50872.1 - 3.8e-16 59.6 33.8 3.8e-16 59.6 33.8 4.5 3 1 0 3 3 2 1 Disintegrin Reprolysin_3 PF13582.6 KXG50872.1 - 2.5e-09 37.7 1.4 7.3e-09 36.2 0.1 2.5 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like IMS_HHH PF11798.8 KXG50872.1 - 3.5e-06 27.0 0.0 0.00015 21.9 0.0 3.0 3 0 0 3 3 3 1 IMS family HHH motif Pep_M12B_propep PF01562.19 KXG50872.1 - 0.00075 19.7 0.0 0.0038 17.4 0.0 2.1 2 0 0 2 2 2 1 Reprolysin family propeptide HHH_5 PF14520.6 KXG50872.1 - 0.0013 19.3 0.0 0.0033 18.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Mid2 PF04478.12 KXG50872.1 - 0.0078 16.1 0.7 0.032 14.1 0.7 2.0 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SRP-alpha_N PF04086.13 KXG50873.1 - 0.82 9.5 6.9 0.27 11.1 4.3 1.5 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal C2 PF00168.30 KXG50874.1 - 9e-30 103.0 0.0 9.1e-17 61.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain Fungal_trans PF04082.18 KXG50875.1 - 4.5e-19 68.5 1.2 6.8e-19 67.9 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 KXG50876.1 - 2.4e-22 79.9 0.0 4e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXG50876.1 - 2.9e-17 62.6 0.0 4.6e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Fungal_trans PF04082.18 KXG50876.1 - 0.00098 18.2 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain YihI PF04220.12 KXG50876.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) FabA PF07977.13 KXG50877.1 - 0.038 13.6 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 FabA-like domain Alk_phosphatase PF00245.20 KXG50878.1 - 5.5e-69 233.1 1.5 1.2e-68 232.0 1.5 1.5 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 KXG50878.1 - 3.6e-08 33.2 4.4 1.4e-06 27.9 4.4 2.3 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXG50878.1 - 5.2e-06 26.3 0.3 9.6e-06 25.4 0.3 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KXG50878.1 - 0.00025 19.8 0.4 0.0004 19.1 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KXG50878.1 - 0.02 14.2 0.3 0.039 13.3 0.3 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily HHH_3 PF12836.7 KXG50878.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Aa_trans PF01490.18 KXG50879.1 - 2.4e-39 135.2 38.5 3.1e-39 134.8 38.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MFS_1 PF07690.16 KXG50882.1 - 3.3e-44 151.2 7.3 3.3e-44 151.2 7.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG50882.1 - 3.6e-11 42.6 6.5 3.6e-11 42.6 6.5 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_5 PF05631.14 KXG50882.1 - 2.5e-06 26.7 3.3 1.7e-05 23.9 1.0 2.1 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 KXG50882.1 - 0.0013 17.6 3.1 0.032 13.1 3.4 2.2 2 0 0 2 2 2 1 MFS_1 like family Octopine_DH PF02317.17 KXG50883.1 - 2.4e-43 147.8 0.0 3.7e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.23 KXG50883.1 - 1.7e-07 31.3 0.0 3.6e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_8 PF13450.6 KXG50883.1 - 0.00028 21.0 0.1 0.00057 20.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG50883.1 - 0.0021 17.3 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXG50883.1 - 0.0035 16.5 0.1 0.0064 15.6 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.16 KXG50883.1 - 0.007 16.0 0.0 0.016 14.8 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KXG50883.1 - 0.011 16.3 0.0 0.025 15.1 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.19 KXG50883.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 KXG50883.1 - 0.022 13.9 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KXG50883.1 - 0.028 13.1 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 KXG50883.1 - 0.03 13.9 0.1 0.048 13.2 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXG50883.1 - 0.05 14.2 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG50883.1 - 0.17 11.1 0.2 0.33 10.2 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 KXG50884.1 - 6.3e-16 58.2 0.0 9.9e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG50884.1 - 4.1e-09 36.4 11.7 7e-09 35.7 11.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 KXG50885.1 - 2.9e-14 53.4 0.0 3.8e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KXG50885.1 - 0.08 12.4 0.1 0.21 11.0 0.1 1.6 1 1 1 2 2 2 0 short chain dehydrogenase Aa_trans PF01490.18 KXG50886.1 - 1.4e-40 139.3 32.4 1.7e-40 139.0 32.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.6 KXG50886.1 - 1.3 8.9 6.5 8.9 6.2 0.1 3.4 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase NDUF_B12 PF08122.12 KXG50886.1 - 5 7.3 5.7 2.6 8.2 0.0 3.2 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF2534 PF10749.9 KXG50886.1 - 6.5 7.0 9.5 0.19 11.9 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2534) zf-C2H2 PF00096.26 KXG50887.1 - 1.9e-07 31.2 20.8 0.02 15.4 3.6 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXG50887.1 - 0.00013 22.5 24.1 0.0024 18.6 3.7 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KXG50887.1 - 0.11 12.9 8.0 0.12 12.8 2.8 2.6 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF1272 PF06906.11 KXG50887.1 - 0.25 11.4 3.8 1.5 8.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) zf-H2C2_2 PF13465.6 KXG50887.1 - 0.83 10.2 7.9 2.1 8.9 0.3 3.8 3 1 0 3 3 3 0 Zinc-finger double domain GET2 PF08690.10 KXG50888.1 - 1.2e-14 54.8 7.3 6e-14 52.4 7.3 1.8 1 1 0 1 1 1 1 GET complex subunit GET2 PepSY_TM PF03929.16 KXG50888.1 - 0.21 11.2 0.0 0.21 11.2 0.0 2.2 2 1 0 2 2 2 0 PepSY-associated TM region PALP PF00291.25 KXG50889.1 - 6.1e-64 216.3 1.0 6.1e-64 216.3 1.0 1.9 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.28 KXG50889.1 - 4.5e-28 98.4 0.1 1.2e-27 97.0 0.1 1.8 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXG50889.1 - 9.7e-19 67.3 0.0 3.5e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXG50889.1 - 0.00096 18.9 0.2 0.0024 17.6 0.2 1.7 1 0 0 1 1 1 1 Peptidase family M28 LpxI_N PF17930.1 KXG50889.1 - 0.022 14.7 0.0 0.09 12.7 0.0 2.1 1 0 0 1 1 1 0 LpxI N-terminal domain Peptidase_M20 PF01546.28 KXG50890.1 - 2.2e-34 119.0 0.0 3.3e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KXG50890.1 - 2.1e-05 24.3 0.0 7e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.14 KXG50890.1 - 7.8e-05 22.5 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain AMP-binding PF00501.28 KXG50891.1 - 2.4e-88 296.6 0.0 3.1e-88 296.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG50891.1 - 2.5e-26 92.5 1.4 5.4e-26 91.4 0.3 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KXG50891.1 - 8.8e-17 60.8 0.5 2.2e-16 59.5 0.5 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Nup96 PF12110.8 KXG50892.1 - 1.1e-82 277.5 2.9 1.1e-82 277.5 1.2 1.8 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KXG50892.1 - 9e-50 168.7 0.0 1.5e-49 167.9 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KXG50892.1 - 2.7e-05 24.9 134.5 0.00017 22.4 40.0 10.3 4 3 4 8 8 8 4 Nucleoporin FG repeat region Rep_2 PF01719.17 KXG50893.1 - 3.1 7.5 7.1 51 3.6 7.1 2.4 1 1 0 1 1 1 0 Plasmid replication protein MFS_1 PF07690.16 KXG50894.1 - 5.7e-49 166.9 33.4 3e-46 158.0 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXG50894.1 - 0.57 8.4 6.8 0.25 9.6 3.1 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Complex1_51K PF01512.17 KXG50895.1 - 4.1e-46 156.6 0.0 6.4e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KXG50895.1 - 4.2e-29 100.4 0.3 8.5e-29 99.5 0.3 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KXG50895.1 - 1.2e-08 34.7 0.0 3.7e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 SLBB domain DUF3568 PF12092.8 KXG50895.1 - 0.17 11.9 0.4 0.34 11.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) SET PF00856.28 KXG50896.1 - 0.0001 22.7 0.0 0.00024 21.5 0.0 1.7 2 0 0 2 2 2 1 SET domain SAPS PF04499.15 KXG50897.1 - 4.1e-199 662.4 0.5 2.4e-197 656.6 0.0 2.9 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein Glyco_hydro_26 PF02156.15 KXG50898.1 - 9.1e-74 248.7 3.2 1.1e-73 248.4 3.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Snf7 PF03357.21 KXG50899.1 - 1.5e-43 148.4 15.2 1.8e-43 148.1 15.2 1.0 1 0 0 1 1 1 1 Snf7 DUF3584 PF12128.8 KXG50899.1 - 0.00062 17.4 5.5 0.00076 17.1 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF4201 PF13870.6 KXG50899.1 - 0.0012 18.7 6.7 0.0012 18.7 6.7 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) NPV_P10 PF05531.12 KXG50899.1 - 0.0023 18.3 8.3 0.081 13.4 1.1 2.7 3 0 0 3 3 3 2 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 KXG50899.1 - 0.0052 17.1 4.5 1.2 9.6 0.0 3.5 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Zwint PF15556.6 KXG50899.1 - 0.062 12.8 10.8 0.12 11.8 11.0 1.4 1 1 0 1 1 1 0 ZW10 interactor AF0941-like PF14591.6 KXG50899.1 - 0.062 13.9 4.8 0.1 13.2 4.8 1.3 1 0 0 1 1 1 0 AF0941-like Alpha-2-MRAP_C PF06401.11 KXG50899.1 - 0.071 13.1 4.6 0.1 12.5 2.6 2.0 1 1 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain HHH_2 PF12826.7 KXG50899.1 - 0.089 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF848 PF05852.11 KXG50899.1 - 0.09 12.9 7.1 0.041 14.0 4.4 1.8 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FlaC_arch PF05377.11 KXG50899.1 - 0.19 12.1 8.5 5 7.6 0.0 3.4 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF5082 PF16888.5 KXG50899.1 - 0.23 11.7 9.2 3 8.1 4.7 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Prefoldin_2 PF01920.20 KXG50899.1 - 0.27 11.2 0.0 0.27 11.2 0.0 3.7 2 1 1 3 3 2 0 Prefoldin subunit XhlA PF10779.9 KXG50899.1 - 0.88 9.8 7.0 6.9 7.0 0.0 3.4 2 1 2 4 4 4 0 Haemolysin XhlA Baculo_PEP_C PF04513.12 KXG50899.1 - 1.1 9.3 4.7 8.5 6.4 0.2 2.3 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 KXG50899.1 - 7.1 7.3 11.1 3.9e+02 1.8 8.5 3.6 1 1 1 2 2 2 0 SlyX Nramp PF01566.18 KXG50900.1 - 8.9e-95 317.7 18.4 8.9e-95 317.7 18.4 1.9 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Drf_GBD PF06371.13 KXG50901.1 - 1.1e-16 60.9 3.9 3.3e-10 39.9 0.0 2.7 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Xpo1 PF08389.12 KXG50901.1 - 0.046 13.8 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Exportin 1-like protein DUF218 PF02698.17 KXG50903.1 - 1.8e-09 37.7 0.0 2.7e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Thiolase_N PF00108.23 KXG50904.1 - 4.7e-73 245.8 3.7 4.7e-73 245.8 3.7 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXG50904.1 - 3.1e-44 149.6 0.3 7.3e-44 148.4 0.3 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXG50904.1 - 0.0022 17.6 3.1 0.011 15.3 0.5 2.9 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXG50904.1 - 0.034 14.0 1.9 6.2 6.8 0.1 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III RraA-like PF03737.15 KXG50905.1 - 6.3e-30 104.3 0.2 1.9e-29 102.8 0.2 1.8 1 1 0 1 1 1 1 Aldolase/RraA Acetyltransf_2 PF00797.17 KXG50906.1 - 1.6e-24 87.1 0.0 3e-24 86.1 0.0 1.5 1 1 0 1 1 1 1 N-acetyltransferase MWFE PF15879.5 KXG50907.1 - 2.3e-28 98.1 0.8 2.8e-28 97.9 0.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit MOZ_SAS PF01853.18 KXG50908.1 - 3.5e-74 248.4 0.0 5.6e-74 247.7 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KXG50908.1 - 8.6e-22 76.5 2.3 1.7e-21 75.5 2.3 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 KXG50908.1 - 1.5e-08 34.6 11.4 4.1e-08 33.2 11.4 1.8 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 KXG50908.1 - 0.6 10.1 18.1 0.17 11.8 14.1 2.1 2 0 0 2 2 2 0 PHD-finger Velvet PF11754.8 KXG50909.1 - 1.8e-47 162.4 10.6 2.5e-32 112.8 0.5 3.2 2 1 1 3 3 3 3 Velvet factor BP28CT PF08146.12 KXG50910.1 - 0.061 13.2 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 BP28CT (NUC211) domain SNF2_N PF00176.23 KXG50911.1 - 1.5e-41 142.3 0.0 5.9e-37 127.2 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain HMG_box PF00505.19 KXG50911.1 - 2.2e-22 79.2 0.5 4.5e-22 78.2 0.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXG50911.1 - 1.2e-08 35.4 0.6 5.2e-08 33.4 0.2 2.2 2 0 0 2 2 2 1 HMG-box domain Helicase_C PF00271.31 KXG50911.1 - 5.7e-08 33.1 0.1 1.1e-07 32.1 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_18 PF13238.6 KXG50911.1 - 0.00099 19.7 0.0 0.0027 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KXG50911.1 - 0.0028 18.2 0.2 0.38 11.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain PRK PF00485.18 KXG50911.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Lipase_GDSL_2 PF13472.6 KXG50912.1 - 0.011 16.2 0.0 0.02 15.3 0.0 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Ribosomal_S6e PF01092.19 KXG50913.1 - 4.8e-55 184.9 0.0 1.1e-54 183.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e Pribosyltran_N PF13793.6 KXG50914.1 - 1.2e-45 154.2 0.4 1.1e-44 151.0 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KXG50914.1 - 5.2e-40 137.4 1.7 3.1e-33 115.3 0.7 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KXG50914.1 - 1.1e-17 64.0 1.0 1.5e-16 60.3 0.6 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXG50914.1 - 0.00022 20.7 0.2 0.00041 19.9 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF913 PF06025.12 KXG50915.1 - 3.6e-130 434.2 0.0 3.6e-130 434.2 0.0 5.5 5 1 0 5 5 5 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KXG50915.1 - 2.1e-113 379.4 4.4 2.1e-113 379.4 4.4 2.9 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) HECT PF00632.25 KXG50915.1 - 5.4e-95 318.4 0.0 8.9e-95 317.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 KXG50915.1 - 2.1e-29 100.0 20.5 1.3e-10 40.4 0.8 4.1 3 0 0 3 3 3 3 Ubiquitin binding region An_peroxidase PF03098.15 KXG50916.1 - 6.4e-39 133.9 0.1 2e-27 96.0 0.1 3.3 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KXG50916.1 - 2.4e-08 33.2 0.0 3e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Cytochrome P450 SpoVIF PF14069.6 KXG50916.1 - 0.05 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Stage VI sporulation protein F Steroid_dh PF02544.16 KXG50917.1 - 3.1e-31 108.4 1.0 4.3e-31 107.9 1.0 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KXG50917.1 - 1.7e-06 27.7 1.4 2.6e-06 27.2 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KXG50917.1 - 0.0049 17.2 0.3 0.0049 17.2 0.3 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase Glyco_transf_34 PF05637.12 KXG50918.1 - 3.2e-59 200.5 0.0 4.3e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family CN_hydrolase PF00795.22 KXG50918.1 - 1.2e-32 113.3 0.0 1.6e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_L28 PF00830.19 KXG50920.1 - 2.5e-17 62.8 0.6 4.9e-17 61.9 0.6 1.4 1 0 0 1 1 1 1 Ribosomal L28 family TIP49 PF06068.13 KXG50921.1 - 3.8e-167 555.9 0.0 4.5e-167 555.6 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KXG50921.1 - 4.6e-20 71.5 0.0 1.4e-19 70.0 0.0 1.9 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 KXG50921.1 - 3.6e-11 43.6 0.1 3.8e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXG50921.1 - 2e-10 40.6 0.1 7.3e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXG50921.1 - 7.4e-06 26.3 0.1 0.043 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXG50921.1 - 0.00013 22.5 0.1 0.0016 18.9 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KXG50921.1 - 0.00013 22.3 0.7 0.086 13.2 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KXG50921.1 - 0.00081 19.4 0.2 0.19 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KXG50921.1 - 0.00083 19.6 0.1 0.0019 18.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KXG50921.1 - 0.0015 18.3 0.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 KXG50921.1 - 0.006 15.9 0.3 0.015 14.6 0.3 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.6 KXG50921.1 - 0.0075 15.9 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXG50921.1 - 0.016 14.6 0.1 0.76 9.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 KXG50921.1 - 0.042 13.2 0.1 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ATPase PF06745.13 KXG50921.1 - 0.048 13.0 0.7 0.15 11.4 0.1 1.9 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 KXG50921.1 - 0.057 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KXG50921.1 - 0.058 13.9 0.0 0.28 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KXG50921.1 - 0.071 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KXG50921.1 - 0.1 12.1 0.1 0.43 10.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 KXG50921.1 - 0.11 12.2 0.2 1.7 8.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain TetR_C_30 PF17939.1 KXG50921.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain V-SNARE PF05008.15 KXG50922.1 - 2.3e-20 72.8 4.5 2.3e-20 72.8 4.5 2.4 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KXG50922.1 - 1.3e-14 54.2 3.4 1.3e-14 54.2 3.4 2.6 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Thump_like PF18096.1 KXG50922.1 - 0.0062 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 THUMP domain-like BORCS8 PF10167.9 KXG50922.1 - 0.0082 16.1 0.9 0.3 11.1 0.0 2.4 2 0 0 2 2 2 1 BLOC-1-related complex sub-unit 8 YqjK PF13997.6 KXG50922.1 - 0.13 12.6 6.9 2 8.7 0.0 3.4 3 0 0 3 3 3 0 YqjK-like protein CHDCT2 PF08074.11 KXG50922.1 - 0.17 12.1 4.0 0.96 9.6 0.5 2.1 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Fusion_gly PF00523.18 KXG50922.1 - 0.2 9.9 2.8 0.35 9.1 0.2 2.3 2 0 0 2 2 2 0 Fusion glycoprotein F0 zf-C4H2 PF10146.9 KXG50922.1 - 1.8 8.8 9.7 0.8 10.0 3.1 2.3 1 1 1 2 2 2 0 Zinc finger-containing protein Exonuc_VII_L PF02601.15 KXG50922.1 - 3.5 7.1 14.2 18 4.8 14.2 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4083 PF13314.6 KXG50922.1 - 6.4 6.8 9.9 22 5.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF2407_C PF13373.6 KXG50923.1 - 1.2e-43 148.7 0.2 1.9e-43 148.0 0.2 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KXG50923.1 - 2.2e-34 118.2 0.1 2e-33 115.0 0.0 2.1 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXG50923.1 - 0.06 13.5 0.1 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXG50923.1 - 0.066 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family GRA6 PF05084.13 KXG50923.1 - 0.13 12.2 0.4 0.27 11.2 0.1 1.6 2 0 0 2 2 2 0 Granule antigen protein (GRA6) Fe-S_biosyn PF01521.20 KXG50924.1 - 1e-18 67.5 0.0 1.4e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF1741 PF08427.10 KXG50925.1 - 5.9e-93 310.8 0.0 1.1e-92 309.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) DUF3383 PF11863.8 KXG50925.1 - 0.036 13.1 0.8 0.059 12.4 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) MBOAT_2 PF13813.6 KXG50925.1 - 0.1 12.9 0.1 0.33 11.3 0.1 1.8 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family MRG PF05712.13 KXG50926.1 - 1.3e-56 191.1 0.2 1.9e-56 190.6 0.2 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KXG50926.1 - 1.4e-08 34.5 2.6 3.3e-08 33.3 2.6 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KXG50926.1 - 0.046 13.6 2.6 0.13 12.2 2.6 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Cnl2_NKP2 PF09447.10 KXG50927.1 - 1.4e-26 92.4 1.0 1.4e-26 92.4 1.0 2.0 2 0 0 2 2 2 1 Cnl2/NKP2 family protein HrpB7 PF09486.10 KXG50927.1 - 0.015 15.7 2.4 0.021 15.2 2.4 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) KfrA_N PF11740.8 KXG50927.1 - 0.017 15.8 1.6 0.46 11.2 0.3 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Mod_r PF07200.13 KXG50927.1 - 0.022 14.8 0.6 0.032 14.3 0.6 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF948 PF06103.11 KXG50927.1 - 0.032 14.5 0.1 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 KXG50927.1 - 0.04 14.4 4.8 1.7 9.2 2.2 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF2203 PF09969.9 KXG50927.1 - 0.041 14.6 0.7 0.5 11.1 0.1 2.2 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) GlutR_dimer PF00745.20 KXG50927.1 - 0.13 12.7 2.5 0.15 12.5 0.8 2.0 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Phage_Mu_Gam PF07352.12 KXG50927.1 - 0.28 11.1 2.9 7 6.5 0.6 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein ABC_tran_CTD PF16326.5 KXG50927.1 - 5.1 7.4 9.1 20 5.5 1.8 2.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain Ctf8 PF09696.10 KXG50928.1 - 1.9e-45 154.7 0.1 1.7e-44 151.6 0.1 1.9 1 1 0 1 1 1 1 Ctf8 NHR2 PF08788.11 KXG50928.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 NHR2 domain like Glyoxalase PF00903.25 KXG50929.1 - 4.4e-18 65.7 0.2 5.9e-14 52.4 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXG50929.1 - 1e-11 45.0 0.1 9e-05 22.7 0.0 3.0 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KXG50929.1 - 3.2e-06 27.4 0.0 0.11 12.6 0.0 3.2 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KXG50929.1 - 0.00023 21.4 0.0 0.19 11.9 0.0 3.0 3 0 0 3 3 3 2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Dabb PF07876.12 KXG50930.1 - 2.9e-12 47.0 0.0 3.2e-12 46.9 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Nepo_coat_N PF03689.15 KXG50930.1 - 0.14 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Nepovirus coat protein, N-terminal domain RabGAP-TBC PF00566.18 KXG50931.1 - 2.7e-52 177.5 0.6 1.8e-51 174.9 0.0 2.6 3 1 0 3 3 3 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 KXG50931.1 - 0.2 11.8 15.5 1.1 9.4 7.2 3.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Z1 PF10593.9 KXG50931.1 - 0.75 9.2 7.4 1.7 8.1 7.4 1.6 1 0 0 1 1 1 0 Z1 domain HALZ PF02183.18 KXG50931.1 - 3.8 7.8 6.1 0.86 9.9 0.7 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper YabA PF06156.13 KXG50931.1 - 5.4 7.7 18.9 1.5 9.5 3.2 4.2 2 1 2 4 4 4 0 Initiation control protein YabA PPTA PF01239.22 KXG50932.1 - 1.1e-37 126.7 12.9 9.8e-08 31.5 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PHM7_cyt PF14703.6 KXG50932.1 - 0.06 13.6 0.1 1.5 9.0 0.0 2.4 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter WD40 PF00400.32 KXG50933.1 - 5.6e-09 36.5 0.8 0.00014 22.6 0.0 5.7 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG50933.1 - 2.5e-07 30.9 0.0 0.022 15.1 0.0 4.2 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KXG50935.1 - 1.5e-24 86.3 0.0 2.4e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KXG50935.1 - 0.088 13.1 0.0 38 4.7 0.0 3.9 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Costars PF14705.6 KXG50935.1 - 0.14 12.3 0.0 0.45 10.7 0.0 1.8 1 0 0 1 1 1 0 Costars Bromodomain PF00439.25 KXG50936.1 - 4.1e-39 132.5 0.8 4.1e-20 71.6 0.1 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KXG50936.1 - 7.5e-21 74.1 1.6 1.8e-20 72.9 1.6 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF3573 PF12097.8 KXG50936.1 - 1.3 7.8 5.0 2.1 7.1 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) HAUS4 PF14735.6 KXG50937.1 - 8.9e-08 32.1 1.5 8.9e-08 32.1 1.5 2.0 2 1 0 2 2 2 1 HAUS augmin-like complex subunit 4 DUF1843 PF08898.10 KXG50937.1 - 0.19 12.2 4.4 0.42 11.1 0.2 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) zf-CSL PF05207.13 KXG50938.1 - 7.5e-23 80.0 0.3 9.2e-23 79.7 0.3 1.1 1 0 0 1 1 1 1 CSL zinc finger Frataxin_Cyay PF01491.16 KXG50939.1 - 4.7e-35 119.9 0.1 6.9e-35 119.4 0.1 1.2 1 0 0 1 1 1 1 Frataxin-like domain Glyco_hydro_cc PF11790.8 KXG50940.1 - 8.2e-68 228.5 0.9 9.4e-68 228.3 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF3243 PF11588.8 KXG50940.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) Aa_trans PF01490.18 KXG50942.1 - 1.4e-48 165.7 31.4 1.6e-48 165.5 31.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Vma12 PF11712.8 KXG50942.1 - 1.2 9.2 3.7 0.5 10.4 0.1 2.2 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase p450 PF00067.22 KXG50943.1 - 2.5e-77 260.6 0.0 3.1e-77 260.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 KXG50945.1 - 3.8e-87 293.0 22.0 4.6e-87 292.7 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG50945.1 - 1.5e-24 86.6 34.6 1.5e-24 86.6 34.6 2.4 1 1 2 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG50945.1 - 8.1e-06 24.5 2.5 1.7e-05 23.5 2.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TPR_19 PF14559.6 KXG50945.1 - 0.19 12.2 0.0 0.38 11.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat OATP PF03137.20 KXG50945.1 - 1.2 7.4 10.0 2.5 6.3 1.3 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF2530 PF10745.9 KXG50945.1 - 5.8 7.2 13.3 0.097 12.9 3.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) OppC_N PF12911.7 KXG50945.1 - 9.6 6.3 7.8 0.93 9.5 0.3 3.0 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Glyco_transf_25 PF01755.17 KXG50946.1 - 1.3e-06 28.4 0.0 0.00026 20.9 0.0 2.5 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) FAD_binding_3 PF01494.19 KXG50947.1 - 5.1e-15 55.6 0.2 3.1e-14 53.0 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain MFS_1 PF07690.16 KXG50948.1 - 3.4e-47 161.1 44.1 3.4e-47 161.1 44.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Response_reg PF00072.24 KXG50949.1 - 4.3e-24 84.9 0.2 1.1e-23 83.6 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KXG50949.1 - 7.2e-23 81.2 0.0 1.4e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KXG50949.1 - 2.9e-09 36.8 0.0 6.9e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 KXG50949.1 - 0.00013 22.2 0.1 0.00034 20.8 0.0 1.8 1 1 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KXG50949.1 - 0.00054 20.2 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_7 PF12860.7 KXG50949.1 - 0.0049 17.0 0.7 0.34 11.1 0.0 3.4 3 1 0 3 3 3 1 PAS fold PAS_9 PF13426.7 KXG50949.1 - 0.023 14.9 0.0 0.095 13.0 0.0 2.2 1 0 0 1 1 1 0 PAS domain PAS_8 PF13188.7 KXG50949.1 - 0.11 12.5 0.0 0.52 10.4 0.0 2.2 1 0 0 1 1 1 0 PAS domain HATPase_c_5 PF14501.6 KXG50949.1 - 0.13 12.2 0.8 7 6.6 0.0 3.2 3 0 0 3 3 3 0 GHKL domain p450 PF00067.22 KXG50950.1 - 1.6e-50 172.3 0.0 2.8e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 PIG-X PF08320.12 KXG50950.1 - 0.013 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 PIG-X / PBN1 Fungal_trans_2 PF11951.8 KXG50951.1 - 6.7e-10 38.3 0.2 2.3e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG50951.1 - 3e-07 30.4 10.5 4.6e-07 29.8 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polyketide_cyc2 PF10604.9 KXG50952.1 - 1.1e-08 35.4 0.0 1.4e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MFS_1 PF07690.16 KXG50953.1 - 1.2e-27 96.8 23.2 1.2e-27 96.8 23.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG50953.1 - 3.7e-07 29.4 2.7 3.7e-07 29.4 2.7 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXG50953.1 - 0.0016 16.9 0.5 0.0028 16.1 0.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) APH PF01636.23 KXG50954.1 - 1.9e-13 50.9 0.0 5e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Zwint PF15556.6 KXG50954.1 - 0.063 12.8 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 ZW10 interactor Acyl-CoA_dh_M PF02770.19 KXG50955.1 - 0.0011 19.2 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Abhydrolase_6 PF12697.7 KXG50956.1 - 1.1e-14 55.6 0.0 1.4e-14 55.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 KXG50956.1 - 0.00068 19.5 0.0 0.0027 17.6 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_5 PF12695.7 KXG50956.1 - 0.0053 16.5 0.1 0.0077 16.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 KXG50956.1 - 0.042 13.4 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) EIIA-man PF03610.16 KXG50956.1 - 0.06 13.6 0.0 0.089 13.0 0.0 1.3 1 0 0 1 1 1 0 PTS system fructose IIA component PE-PPE PF08237.11 KXG50956.1 - 0.068 12.7 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Hydrolase_4 PF12146.8 KXG50956.1 - 0.17 11.1 0.1 0.42 9.8 0.1 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXG50956.1 - 0.21 11.2 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.16 KXG50958.1 - 2.5e-36 125.4 97.6 6.6e-34 117.4 57.8 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Rhodanese PF00581.20 KXG50960.1 - 9.7e-33 112.9 0.0 2.4e-07 31.3 0.0 4.4 4 0 0 4 4 4 4 Rhodanese-like domain TPR_1 PF00515.28 KXG50962.1 - 5.6e-05 22.8 10.0 0.00016 21.4 0.2 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXG50962.1 - 0.00013 21.7 3.8 0.29 11.3 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXG50962.1 - 0.00097 19.1 0.1 0.00097 19.1 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXG50962.1 - 0.0042 16.7 9.3 0.08 12.6 0.1 4.1 6 0 0 6 6 6 2 TPR repeat TPR_19 PF14559.6 KXG50962.1 - 0.4 11.2 7.0 12 6.4 0.4 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXG50962.1 - 0.44 10.9 5.3 1.6 9.1 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXG50962.1 - 1.7 9.0 14.4 23 5.4 0.1 4.8 4 2 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXG50962.1 - 1.9 9.5 10.0 12 7.1 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DIOX_N PF14226.6 KXG50963.1 - 4.8e-20 72.5 0.0 1.1e-19 71.3 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG50963.1 - 4.6e-14 52.7 0.0 8.2e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Beta-lactamase PF00144.24 KXG50964.1 - 1e-29 103.9 0.0 1.7e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase GerPE PF10970.8 KXG50964.1 - 0.08 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Spore germination protein GerPE Sugar_tr PF00083.24 KXG50966.1 - 3.9e-100 335.8 22.0 4.7e-100 335.6 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG50966.1 - 8.7e-28 97.2 18.8 8.7e-28 97.2 18.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Pox_A14 PF05767.12 KXG50966.1 - 0.0074 16.4 0.3 0.046 13.9 0.3 2.4 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 SfLAP PF11139.8 KXG50966.1 - 0.23 10.9 8.6 3.5 7.0 0.4 3.5 2 2 1 3 3 3 0 Sap, sulfolipid-1-addressing protein Hep_59 PF07052.11 KXG50967.1 - 1.2e-17 64.6 0.1 1.2e-17 64.6 0.1 2.7 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Actin PF00022.19 KXG50968.1 - 1.1e-147 492.0 0.0 1.2e-147 491.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXG50968.1 - 0.0044 15.9 0.0 1.3 7.8 0.0 2.9 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 KXG50968.1 - 0.037 14.4 0.1 0.12 12.8 0.1 1.9 2 1 0 2 2 2 0 Cell division protein FtsA Arf PF00025.21 KXG50969.1 - 2.2e-43 147.7 0.0 2.6e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KXG50969.1 - 4.5e-19 68.6 0.0 5.2e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXG50969.1 - 4.2e-15 56.0 0.0 6e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXG50969.1 - 7.7e-08 32.4 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXG50969.1 - 7.8e-07 28.7 0.0 9.5e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KXG50969.1 - 9.4e-06 25.2 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KXG50969.1 - 0.00018 20.8 0.1 0.00096 18.4 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 KXG50969.1 - 0.0049 16.9 0.1 0.0079 16.2 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 KXG50969.1 - 0.011 15.8 0.1 0.073 13.1 0.1 1.9 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.18 KXG50969.1 - 0.057 13.0 0.2 0.19 11.2 0.0 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B DUF1979 PF09322.10 KXG50969.1 - 0.06 13.3 0.5 3.2 7.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) RsgA_GTPase PF03193.16 KXG50969.1 - 0.12 12.3 0.1 12 5.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase RNA_pol_Rpb2_6 PF00562.28 KXG50970.1 - 2.6e-115 385.6 0.3 3.5e-115 385.2 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXG50970.1 - 1.3e-36 126.1 0.0 2e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KXG50970.1 - 1.5e-27 95.6 0.0 3.6e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 KXG50970.1 - 1.9e-26 91.8 0.0 4.4e-26 90.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 KXG50970.1 - 1.3e-23 83.6 0.0 2.8e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KXG50970.1 - 1.9e-15 57.0 0.0 1.7e-14 54.0 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 Sugar_tr PF00083.24 KXG50971.1 - 5.6e-88 295.8 25.4 6.5e-88 295.6 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG50971.1 - 2.6e-20 72.7 24.6 2.6e-20 72.7 24.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG50971.1 - 1.1 8.1 15.7 0.022 13.7 6.7 2.1 2 0 0 2 2 2 0 MFS_1 like family Alpha-amylase PF00128.24 KXG50972.1 - 3.4e-119 398.4 2.2 4.1e-116 388.2 0.4 2.1 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KXG50972.1 - 2e-07 31.0 0.0 5.8e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KXG50972.1 - 0.012 14.7 0.0 0.027 13.6 0.0 1.5 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Staygreen PF12638.7 KXG50972.1 - 0.021 14.6 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 Staygreen protein MAM33 PF02330.16 KXG50972.1 - 0.026 14.5 0.8 0.078 12.9 0.6 1.8 2 0 0 2 2 2 0 Mitochondrial glycoprotein Fungal_trans PF04082.18 KXG50973.1 - 6.6e-05 22.1 0.5 0.001 18.2 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Rhabdo_ncap_2 PF03216.13 KXG50973.1 - 0.08 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleoprotein Proteasome PF00227.26 KXG50974.1 - 3.1e-42 144.2 0.4 3.7e-40 137.4 0.4 2.1 1 1 0 1 1 1 1 Proteasome subunit Pil1 PF13805.6 KXG50975.1 - 3.2e-98 328.4 6.5 4.2e-98 328.1 6.5 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 DUF4559 PF15112.6 KXG50975.1 - 0.011 15.4 0.5 0.014 15.1 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Spectrin PF00435.21 KXG50975.1 - 0.16 12.4 2.9 0.35 11.4 1.5 2.2 2 0 0 2 2 2 0 Spectrin repeat Seryl_tRNA_N PF02403.22 KXG50975.1 - 0.27 11.5 4.5 0.22 11.8 2.3 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CCDC-167 PF15188.6 KXG50975.1 - 1.2 9.5 6.2 0.43 11.0 1.5 2.5 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DivIC PF04977.15 KXG50975.1 - 1.5 8.7 8.8 0.15 11.8 0.5 2.8 2 1 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 KXG50975.1 - 1.5 9.4 8.3 11 6.6 6.4 2.4 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF349 PF03993.12 KXG50975.1 - 2.5 8.4 6.0 7.8 6.9 3.6 3.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) SWI-SNF_Ssr4 PF08549.10 KXG50976.1 - 2e-228 760.7 23.5 2.3e-213 710.9 4.9 2.9 1 1 2 3 3 3 3 Fungal domain of unknown function (DUF1750) MFS_1 PF07690.16 KXG50977.1 - 1.6e-30 106.3 28.0 1.6e-30 106.3 28.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG50977.1 - 0.0062 15.4 2.4 0.0062 15.4 2.4 2.1 3 0 0 3 3 3 1 MFS_1 like family Thi4 PF01946.17 KXG50979.1 - 2e-110 367.6 0.0 2.5e-110 367.3 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KXG50979.1 - 1.9e-08 34.3 0.2 1.6e-07 31.3 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG50979.1 - 2.1e-05 24.6 0.6 6.3e-05 23.1 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXG50979.1 - 5.6e-05 22.4 0.4 9.7e-05 21.6 0.4 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXG50979.1 - 0.00039 20.5 0.2 0.0015 18.6 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXG50979.1 - 0.00079 18.7 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG50979.1 - 0.0014 17.8 1.8 0.014 14.5 1.5 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KXG50979.1 - 0.007 15.7 0.1 0.01 15.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXG50979.1 - 0.042 13.2 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXG50979.1 - 0.054 12.7 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXG50979.1 - 0.15 10.9 0.2 0.21 10.4 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 KXG50979.1 - 0.2 10.3 0.5 0.39 9.4 0.5 1.4 1 0 0 1 1 1 0 HI0933-like protein Exo_endo_phos PF03372.23 KXG50980.1 - 1.1e-15 57.8 0.1 1.8e-15 57.1 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Luciferase_cat PF10285.9 KXG50980.1 - 0.15 11.4 0.1 0.24 10.8 0.1 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain WD40 PF00400.32 KXG50981.1 - 2.9e-48 160.8 17.9 9.4e-12 45.3 0.2 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG50981.1 - 6.5e-18 64.8 0.1 7.7e-05 22.9 0.0 6.2 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXG50981.1 - 3.2e-09 37.0 0.0 6.9e-05 22.8 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXG50981.1 - 2.8e-06 26.3 9.7 0.13 10.9 0.1 5.2 3 2 3 6 6 6 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXG50981.1 - 3.7e-05 22.9 0.3 0.92 8.4 0.0 3.8 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KXG50981.1 - 0.00011 21.6 0.0 0.023 14.0 0.0 3.0 2 1 1 3 3 3 1 WD40-like domain Nbas_N PF15492.6 KXG50981.1 - 0.044 13.1 0.3 5 6.4 0.1 3.2 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 KXG50981.1 - 0.046 11.7 0.0 0.062 11.3 0.0 1.1 1 0 0 1 1 1 0 IKI3 family VID27 PF08553.10 KXG50981.1 - 0.062 12.4 0.0 0.26 10.3 0.0 2.1 1 1 0 1 1 1 0 VID27 C-terminal WD40-like domain FAM150 PF15129.6 KXG50981.1 - 0.19 11.9 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 FAM150 family HTH_32 PF13565.6 KXG50982.1 - 3.3e-08 34.0 4.0 0.0004 20.9 0.1 2.4 1 1 1 2 2 2 2 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KXG50982.1 - 0.0083 16.4 0.5 0.035 14.4 0.0 2.0 2 0 0 2 2 2 1 Transposase Complex1_LYR PF05347.15 KXG50982.1 - 0.025 14.6 0.8 0.054 13.6 0.4 1.8 2 0 0 2 2 2 0 Complex 1 protein (LYR family) TRP PF06011.12 KXG50983.1 - 3.1e-138 461.1 6.0 4.1e-138 460.7 6.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXG50983.1 - 9.1e-41 139.5 0.6 1.4e-40 138.8 0.6 1.3 1 0 0 1 1 1 1 ML-like domain Shisa PF13908.6 KXG50983.1 - 0.00061 20.1 4.7 0.26 11.5 0.2 3.0 3 0 0 3 3 3 2 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 KXG50983.1 - 0.04 13.8 12.5 0.56 10.1 0.1 4.0 3 1 0 3 3 3 0 TMEM154 protein family DUF1180 PF06679.12 KXG50983.1 - 0.051 14.0 9.5 1.1 9.7 0.6 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Abi_C PF14355.6 KXG50983.1 - 0.14 12.3 0.6 0.33 11.1 0.6 1.6 1 0 0 1 1 1 0 Abortive infection C-terminus DUF3169 PF11368.8 KXG50983.1 - 0.16 11.4 8.2 0.31 10.5 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) HemY_N PF07219.13 KXG50983.1 - 0.19 11.9 7.1 2.4 8.4 0.8 3.5 3 1 0 3 3 3 0 HemY protein N-terminus AJAP1_PANP_C PF15298.6 KXG50983.1 - 0.31 11.2 6.1 1.8 8.7 0.1 2.5 2 0 0 2 2 2 0 AJAP1/PANP C-terminus ETRAMP PF09716.10 KXG50983.1 - 0.46 10.6 0.0 0.46 10.6 0.0 3.6 4 0 0 4 4 2 0 Malarial early transcribed membrane protein (ETRAMP) CCDC24 PF15669.5 KXG50983.1 - 1.4 8.8 3.9 2.5 7.9 3.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF2663 PF10864.8 KXG50983.1 - 1.6 9.2 11.9 0.35 11.3 2.7 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2663) RRM_1 PF00076.22 KXG50984.1 - 1.5e-33 114.4 0.2 2.1e-15 56.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXG50984.1 - 1.2e-10 41.4 0.1 0.00025 21.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KXG50984.1 - 0.002 18.1 0.0 0.59 10.2 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KXG50984.1 - 0.0037 17.3 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif RabGAP-TBC PF00566.18 KXG50985.1 - 1.4e-50 172.0 0.0 2.3e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CENP-B_dimeris PF09026.10 KXG50985.1 - 1.8 9.0 6.0 3.3 8.1 6.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RrnaAD PF00398.20 KXG50986.1 - 7.8e-64 215.3 0.0 1.8e-63 214.1 0.0 1.6 1 1 1 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KXG50986.1 - 5.8e-08 33.3 0.0 1.5e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG50986.1 - 2e-05 25.2 0.0 5e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXG50986.1 - 3.1e-05 23.8 0.0 5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KXG50986.1 - 0.00044 20.1 0.0 0.00082 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG50986.1 - 0.00052 20.7 0.0 0.0012 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG50986.1 - 0.00069 19.4 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXG50986.1 - 0.0025 17.1 0.0 0.0041 16.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 KXG50986.1 - 0.0076 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KXG50986.1 - 0.0077 15.8 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXG50986.1 - 0.11 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_28 PF02636.17 KXG50986.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.7 KXG50986.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PRP1_N PF06424.12 KXG50987.1 - 2e-52 177.5 7.5 5.1e-52 176.2 7.5 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 KXG50987.1 - 3.8e-29 101.0 14.7 1.2e-07 32.2 0.3 9.6 6 3 2 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 KXG50987.1 - 1.4e-28 97.1 35.1 1.6e-05 25.3 0.2 14.2 5 3 10 15 15 13 10 Tetratricopeptide repeat TPR_16 PF13432.6 KXG50987.1 - 5.5e-14 52.5 23.6 0.0034 18.0 0.0 8.1 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXG50987.1 - 4.5e-13 48.2 11.2 0.32 11.2 0.0 9.5 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXG50987.1 - 8.6e-11 41.3 0.8 0.45 10.3 0.0 7.7 7 1 1 8 8 8 2 TPR repeat TPR_8 PF13181.6 KXG50987.1 - 3.3e-08 33.1 0.2 3.2 8.2 0.0 7.0 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXG50987.1 - 4.9e-07 29.3 0.4 0.15 12.0 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXG50987.1 - 7.6e-07 29.1 6.0 6.7 7.3 0.0 9.2 11 1 1 12 12 10 1 Tetratricopeptide repeat TPR_21 PF09976.9 KXG50987.1 - 1.9e-05 24.4 13.7 0.027 14.2 2.9 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 KXG50987.1 - 0.00024 21.2 6.3 0.23 11.6 0.0 5.4 4 1 1 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG50987.1 - 0.00097 19.3 1.0 0.42 10.9 0.1 4.3 4 1 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 ZNRF_3_ecto PF18212.1 KXG50987.1 - 0.0046 16.9 0.5 6.1 6.9 0.1 3.9 4 0 0 4 4 4 1 ZNRF-3 Ectodomain TPR_4 PF07721.14 KXG50987.1 - 0.012 16.1 11.7 6.8 7.6 0.1 6.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Suf PF05843.14 KXG50987.1 - 0.014 15.4 4.1 4.7 7.1 0.0 3.8 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) TPR_7 PF13176.6 KXG50987.1 - 0.016 15.2 1.2 67 3.9 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXG50987.1 - 0.028 15.1 13.0 94 4.0 0.0 8.7 9 0 0 9 9 8 0 Tetratricopeptide repeat PTPRCAP PF15713.5 KXG50987.1 - 0.069 13.4 6.9 0.21 11.9 6.9 1.8 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated AdenylateSensor PF16579.5 KXG50987.1 - 0.086 13.3 1.1 12 6.4 0.0 3.7 3 1 1 4 4 3 0 Adenylate sensor of SNF1-like protein kinase Ribosomal_60s PF00428.19 KXG50987.1 - 1.8 9.2 7.1 0.78 10.4 1.8 3.1 3 0 0 3 3 2 0 60s Acidic ribosomal protein SAGA-Tad1 PF12767.7 KXG50988.1 - 2.2e-52 178.2 0.0 4.3e-52 177.2 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit FUSC_2 PF13515.6 KXG50988.1 - 6.9e-30 103.8 10.8 6.9e-30 103.8 10.8 2.7 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KXG50988.1 - 3.4e-05 23.8 0.4 7.6e-05 22.7 0.4 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ALMT PF11744.8 KXG50988.1 - 0.0043 15.9 17.5 0.27 10.0 0.0 3.7 3 1 0 3 3 3 2 Aluminium activated malate transporter FUSC PF04632.12 KXG50988.1 - 0.14 10.7 18.5 2.4 6.6 0.1 3.7 3 0 0 3 3 3 0 Fusaric acid resistance protein family Phage_holin_3_1 PF05106.12 KXG50988.1 - 0.19 12.2 1.3 0.85 10.1 1.3 2.2 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) Phage_holin_Dp1 PF16938.5 KXG50988.1 - 0.33 11.2 4.5 1.2 9.4 0.1 3.3 3 0 0 3 3 3 0 Putative phage holin Dp-1 WD40 PF00400.32 KXG50989.1 - 9.3e-23 80.1 30.0 0.00029 21.6 0.1 9.9 9 1 1 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG50989.1 - 2.5e-15 56.6 4.9 0.00032 20.9 0.0 7.2 5 3 3 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S18 PF01084.20 KXG50989.1 - 3.6e-14 52.7 0.0 7.8e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 RAB3GAP2_N PF14655.6 KXG50989.1 - 0.14 11.3 0.0 0.35 10.1 0.0 1.6 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CorA PF01544.18 KXG50990.1 - 1.4e-05 24.6 0.0 4.5e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PPR_2 PF13041.6 KXG50990.1 - 1.6e-05 25.0 1.4 5.8 7.2 0.0 6.8 6 2 0 6 6 6 1 PPR repeat family PPR PF01535.20 KXG50990.1 - 3e-05 24.0 3.4 0.48 10.8 0.2 6.5 7 0 0 7 7 7 1 PPR repeat PPR_long PF17177.4 KXG50990.1 - 0.0002 20.8 2.5 0.14 11.5 0.2 3.8 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP DUF5325 PF17259.2 KXG50990.1 - 0.072 13.0 0.4 0.21 11.5 0.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5325) RasGEF_N_2 PF14663.6 KXG50990.1 - 0.5 10.8 2.0 55 4.2 0.0 3.7 3 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain p450 PF00067.22 KXG50991.1 - 5e-77 259.6 0.0 6.1e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidohydro_2 PF04909.14 KXG50992.1 - 1.5e-39 136.6 0.8 1.7e-39 136.4 0.8 1.0 1 0 0 1 1 1 1 Amidohydrolase DUF3982 PF13138.6 KXG50992.1 - 0.054 13.3 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3982) SnoaL_2 PF12680.7 KXG50993.1 - 6.2e-05 23.6 0.1 8.9e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain GMC_oxred_N PF00732.19 KXG50994.1 - 1.1e-55 189.1 0.0 1.6e-55 188.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG50994.1 - 6.9e-37 127.2 0.0 1.2e-36 126.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXG50994.1 - 2.8e-06 26.7 2.5 4e-05 22.9 1.6 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXG50994.1 - 0.00013 21.7 7.7 0.00048 19.8 5.6 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG50994.1 - 0.0025 17.1 0.5 0.0051 16.1 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG50994.1 - 0.0045 17.2 2.6 0.0045 17.2 2.6 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXG50994.1 - 0.0072 15.4 0.3 0.013 14.6 0.3 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KXG50994.1 - 0.011 14.6 0.1 0.017 14.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KXG50994.1 - 0.012 14.9 0.9 0.12 11.6 1.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG50994.1 - 0.07 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KXG50994.1 - 0.092 12.0 0.8 0.14 11.3 0.8 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KXG50994.1 - 0.23 10.8 1.7 4.3 6.6 2.8 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KXG50994.1 - 0.27 9.9 1.2 0.4 9.3 1.2 1.2 1 0 0 1 1 1 0 HI0933-like protein ADH_N PF08240.12 KXG50995.1 - 4.5e-16 58.7 0.9 7.3e-16 58.0 0.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG50995.1 - 1e-14 54.6 0.0 2.1e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXG50995.1 - 0.0028 17.0 0.0 0.0054 16.0 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXG50995.1 - 0.005 16.2 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Haem_degrading PF03928.14 KXG50995.1 - 0.064 13.3 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Haem-degrading ELFV_dehydrog PF00208.21 KXG50995.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase MFS_1 PF07690.16 KXG50996.1 - 1.1e-29 103.5 52.8 2.3e-28 99.1 52.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2784 PF10861.8 KXG50996.1 - 0.0001 22.3 5.1 0.00011 22.2 2.5 2.4 1 1 1 2 2 2 1 Protein of Unknown function (DUF2784) Cation_ATPase_C PF00689.21 KXG50996.1 - 3.4 7.3 18.5 2.9 7.6 13.2 3.0 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus DUF5056 PF16479.5 KXG50996.1 - 9.3 6.6 6.0 2.9 8.2 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) COesterase PF00135.28 KXG50997.1 - 7.7e-66 223.0 0.0 3.1e-65 221.0 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG50997.1 - 1.4e-06 28.3 0.1 5.6e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXG50997.1 - 0.034 13.6 0.2 0.057 12.9 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Gpr1_Fun34_YaaH PF01184.19 KXG50998.1 - 1.3e-38 132.7 18.8 1.6e-38 132.4 18.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF202 PF02656.15 KXG50998.1 - 0.93 10.0 16.2 32 5.1 0.4 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF202) ABC2_membrane PF01061.24 KXG50999.1 - 2.2e-59 200.4 52.1 4.4e-31 108.0 17.3 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KXG50999.1 - 4.1e-45 153.7 0.1 7.6e-22 78.3 0.1 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXG50999.1 - 1.6e-30 104.8 1.8 1.3e-22 79.5 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter AAA_16 PF13191.6 KXG50999.1 - 3e-06 27.7 0.9 0.00043 20.7 0.2 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KXG50999.1 - 1.5e-05 24.8 0.2 0.039 13.7 0.1 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXG50999.1 - 2e-05 24.6 1.2 7e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KXG50999.1 - 3.6e-05 23.7 0.2 0.61 9.8 0.0 3.8 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KXG50999.1 - 0.0014 19.2 0.0 0.26 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_trans_N PF14510.6 KXG50999.1 - 0.0015 19.1 0.2 0.0081 16.8 0.0 2.2 2 0 0 2 2 2 1 ABC-transporter N-terminal SMC_N PF02463.19 KXG50999.1 - 0.0017 17.9 0.2 0.15 11.5 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KXG50999.1 - 0.0018 18.2 1.1 0.63 10.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain ABC2_membrane_3 PF12698.7 KXG50999.1 - 0.003 16.7 11.2 0.003 16.7 11.2 3.6 3 1 1 4 4 4 2 ABC-2 family transporter protein AAA_22 PF13401.6 KXG50999.1 - 0.014 15.7 1.2 4.7 7.5 0.4 3.0 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXG50999.1 - 0.052 13.7 1.1 1 9.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 KXG50999.1 - 0.052 13.6 0.6 0.41 10.7 0.5 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 KXG50999.1 - 0.084 12.6 1.3 3.1 7.6 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 KXG50999.1 - 0.13 11.3 0.2 12 4.8 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein SbcCD_C PF13558.6 KXG50999.1 - 0.13 12.5 0.1 6.1 7.1 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 KXG50999.1 - 0.13 11.9 0.8 8.2 6.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXG50999.1 - 0.15 12.3 0.7 0.46 10.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KXG50999.1 - 0.23 11.9 1.0 13 6.3 0.5 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KXG50999.1 - 0.37 10.6 6.6 0.55 10.0 0.5 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.19 KXG50999.1 - 1.1 8.8 4.2 5 6.7 1.4 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain adh_short_C2 PF13561.6 KXG51000.1 - 7.7e-45 153.3 0.0 9.7e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG51000.1 - 6.4e-33 113.9 0.0 8.1e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG51000.1 - 1.2e-05 25.3 0.0 1.7e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KXG51000.1 - 0.052 12.7 0.0 0.61 9.2 0.0 2.0 1 1 0 1 1 1 0 Male sterility protein NAD_binding_7 PF13241.6 KXG51000.1 - 0.13 12.8 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_4 PF01565.23 KXG51001.1 - 4.2e-21 75.2 0.4 9.2e-21 74.0 0.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG51001.1 - 5.1e-08 32.9 0.6 1e-07 32.0 0.6 1.5 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans PF04082.18 KXG51002.1 - 2.8e-19 69.2 3.1 4.3e-19 68.6 3.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG51002.1 - 2.6e-07 30.6 10.6 7.2e-07 29.2 10.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gon7 PF08738.10 KXG51002.1 - 0.04 14.0 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Gon7 family DivIC PF04977.15 KXG51002.1 - 0.23 11.3 1.4 0.67 9.8 1.4 1.7 1 0 0 1 1 1 0 Septum formation initiator p450 PF00067.22 KXG51003.1 - 6.8e-79 265.8 0.0 8.5e-79 265.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.11 KXG51004.1 - 8.5e-05 22.2 0.2 0.00025 20.7 0.1 1.8 2 0 0 2 2 2 1 Cupin domain 2OG-FeII_Oxy_5 PF13759.6 KXG51004.1 - 0.12 12.8 0.1 14 6.2 0.1 2.5 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase ketoacyl-synt PF00109.26 KXG51005.1 - 6.5e-85 284.7 0.7 1e-84 284.1 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXG51005.1 - 3.2e-64 217.4 0.4 5.4e-64 216.7 0.0 1.6 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.10 KXG51005.1 - 2.2e-62 210.2 0.0 7.3e-62 208.5 0.0 2.0 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 KXG51005.1 - 3.4e-42 143.2 1.7 4.2e-42 142.9 0.4 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXG51005.1 - 3.3e-13 50.1 0.0 7.3e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 KXG51005.1 - 6.5e-13 48.6 0.2 1.5e-12 47.4 0.2 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KXG51005.1 - 1.7e-11 44.3 0.0 5.5e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 KXG51005.1 - 7.4e-07 28.8 0.0 7.8e-06 25.5 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 KXG51005.1 - 4.9e-06 26.1 0.8 2.4e-05 23.8 0.2 2.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KXG51005.1 - 0.24 11.3 0.8 13 5.8 1.4 2.8 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ThrE PF06738.12 KXG51007.1 - 3.4e-71 239.4 15.7 2.1e-63 213.9 5.0 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KXG51007.1 - 5.8e-12 45.9 10.0 5.8e-12 45.9 10.0 2.7 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE Tom5 PF10642.9 KXG51007.1 - 0.63 10.1 2.3 1.6 8.8 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase LOR PF04525.12 KXG51008.1 - 0.0098 15.5 0.1 0.16 11.5 0.0 2.2 2 0 0 2 2 2 1 LURP-one-related ELFV_dehydrog PF00208.21 KXG51009.1 - 2.7e-64 217.2 0.0 4e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KXG51009.1 - 1.2e-16 59.6 0.0 1.3e-11 42.8 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KXG51009.1 - 0.016 15.1 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain TFIIIC_sub6 PF10419.9 KXG51011.1 - 3.2e-23 81.4 0.0 6.6e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Vps62 PF06101.11 KXG51012.1 - 9.6e-12 44.0 1.1 9.6e-12 44.0 1.1 2.1 3 0 0 3 3 3 1 Vacuolar protein sorting-associated protein 62 WD40 PF00400.32 KXG51013.1 - 0.00018 22.2 1.5 1.1 10.2 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat Strabismus PF06638.11 KXG51013.1 - 0.013 14.2 0.5 0.019 13.6 0.5 1.2 1 0 0 1 1 1 0 Strabismus protein STIMATE PF12400.8 KXG51014.1 - 6.9e-40 136.5 5.2 6.9e-40 136.5 5.2 1.7 2 0 0 2 2 2 1 STIMATE family RRM_1 PF00076.22 KXG51015.1 - 9.6e-15 54.2 1.2 1.6e-14 53.5 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXG51015.1 - 5.7e-05 22.7 0.1 8.9e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXG51015.1 - 0.017 14.9 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif JHD PF17811.1 KXG51016.1 - 1.3e-10 41.8 0.7 2.8e-10 40.6 0.7 1.6 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 KXG51016.1 - 7.8e-09 36.0 0.1 8.2e-08 32.7 0.1 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KXG51016.1 - 1.1e-08 35.1 0.0 2.5e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain PHD PF00628.29 KXG51016.1 - 2.1e-08 33.9 5.7 2.1e-08 33.9 5.7 2.7 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 KXG51016.1 - 0.0043 16.6 3.9 0.0053 16.3 2.0 2.3 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 KXG51016.1 - 0.78 10.0 5.1 0.39 11.0 1.2 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain Dickkopf_N PF04706.12 KXG51016.1 - 7.8 7.1 12.2 10 6.7 0.3 2.9 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region Med3 PF11593.8 KXG51017.1 - 1.2 8.3 7.6 1.4 8.0 7.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cu-oxidase_3 PF07732.15 KXG51018.1 - 4.7e-37 126.6 2.6 4.7e-37 126.6 2.6 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXG51018.1 - 1.2e-35 122.2 14.5 2.9e-35 121.0 0.3 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KXG51018.1 - 1.4e-32 113.0 0.3 1.1e-29 103.6 0.1 2.7 2 1 1 3 3 3 2 Multicopper oxidase TPR_2 PF07719.17 KXG51019.1 - 6.9e-11 41.4 5.7 0.0003 20.7 0.0 6.2 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXG51019.1 - 2.9e-09 36.3 0.2 0.0087 15.8 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXG51019.1 - 2.3e-08 33.6 0.0 0.79 10.1 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXG51019.1 - 1.4e-06 28.9 13.6 0.02 15.5 0.3 6.3 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXG51019.1 - 4.2e-06 26.9 5.3 1.6 9.0 0.1 5.7 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXG51019.1 - 0.0001 22.7 4.7 0.12 12.9 0.0 5.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXG51019.1 - 0.00021 21.1 1.7 4.5 7.5 0.0 5.2 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXG51019.1 - 0.00033 20.4 4.7 1.8 8.6 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXG51019.1 - 0.00071 20.2 8.3 0.43 11.5 0.2 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXG51019.1 - 0.071 13.8 4.8 7.8 7.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXG51019.1 - 0.088 13.0 0.0 1.8 8.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Hexokinase_2 PF03727.16 KXG51020.1 - 8e-82 274.3 0.0 9.5e-81 270.7 0.0 2.2 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 KXG51020.1 - 1.1e-74 250.6 0.0 1.2e-73 247.3 0.0 2.1 2 0 0 2 2 2 1 Hexokinase SIR2 PF02146.17 KXG51020.1 - 2.9e-56 190.2 0.0 4.7e-56 189.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family PLCC PF14466.6 KXG51020.1 - 0.039 14.1 0.0 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 PLAT/LH2 and C2-like Ca2+-binding lipoprotein T2SSF PF00482.23 KXG51020.1 - 0.11 12.5 0.5 3.2 7.7 0.0 3.0 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F FGGY_N PF00370.21 KXG51020.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Pup PF05639.11 KXG51020.1 - 0.25 12.3 1.6 0.6 11.1 1.6 1.6 1 0 0 1 1 1 0 Pup-like protein COG4 PF08318.12 KXG51021.1 - 1.5e-124 415.5 0.0 2.2e-124 414.9 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein Ammonium_transp PF00909.21 KXG51022.1 - 2.2e-114 382.3 29.3 2.5e-114 382.1 29.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family E1-E2_ATPase PF00122.20 KXG51023.1 - 6.8e-47 159.3 0.4 2e-46 157.8 0.4 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXG51023.1 - 1e-43 149.2 0.3 1e-43 149.2 0.3 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXG51023.1 - 1.9e-20 74.1 0.9 2e-19 70.7 0.9 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXG51023.1 - 8.7e-20 70.2 0.0 1.7e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KXG51023.1 - 2.4e-13 49.9 0.0 5.1e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXG51023.1 - 8.5e-05 22.4 1.7 0.0007 19.4 1.1 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.13 KXG51024.1 - 2.2e-37 127.6 0.1 4.2e-37 126.7 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KXG51024.1 - 8.7e-08 31.3 0.5 2.3e-07 30.0 0.5 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Zn_clus PF00172.18 KXG51025.1 - 0.0085 16.2 9.2 0.017 15.2 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavokinase PF01687.17 KXG51026.1 - 4e-31 107.6 0.0 6.6e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase SnoaL PF07366.12 KXG51026.1 - 2.5e-05 24.1 0.0 4.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXG51026.1 - 0.087 13.5 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain FadA PF09403.10 KXG51027.1 - 0.14 12.7 1.0 0.53 10.8 0.5 2.2 1 1 0 2 2 2 0 Adhesion protein FadA Chlam_PMP PF02415.17 KXG51027.1 - 1.2 9.8 3.4 76 4.1 0.0 3.6 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Indigoidine_A PF04227.12 KXG51028.1 - 7.6e-116 386.5 0.1 1.2e-115 385.9 0.1 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KXG51028.1 - 2.6e-16 59.8 0.4 7.4e-11 41.9 0.0 2.5 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Ribophorin_I PF04597.14 KXG51029.1 - 9.1e-148 493.1 0.1 1e-147 492.9 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I DUF1460 PF07313.12 KXG51029.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) Myb_Cef PF11831.8 KXG51030.1 - 3.9e-57 193.6 0.6 3.9e-57 193.6 0.6 2.7 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KXG51030.1 - 6.4e-22 77.5 5.8 6.5e-11 42.2 0.6 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXG51030.1 - 6.4e-21 74.4 4.1 5.3e-14 52.2 0.9 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KXG51030.1 - 0.02 15.0 0.3 0.27 11.4 0.0 2.8 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Nop53 PF07767.11 KXG51031.1 - 1.3e-103 347.5 30.1 1.6e-103 347.2 30.1 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) RNase_T PF00929.24 KXG51032.1 - 4.6e-19 69.5 0.0 1.3e-18 68.1 0.0 1.7 1 1 0 1 1 1 1 Exonuclease RNase_H2_suC PF08615.11 KXG51033.1 - 6.8e-25 87.9 0.1 8.2e-25 87.6 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DcpS PF05652.12 KXG51034.1 - 3.6e-34 117.7 0.0 6.2e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KXG51034.1 - 1.1e-29 103.2 0.0 2.1e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding EpuA PF11772.8 KXG51035.1 - 0.011 15.3 0.7 0.011 15.3 0.7 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Peptidase_C12 PF01088.21 KXG51036.1 - 2.4e-53 181.0 0.0 2.9e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 MFS_1 PF07690.16 KXG51037.1 - 8.6e-39 133.4 49.1 8.6e-39 133.4 49.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MT-A70 PF05063.14 KXG51038.1 - 1.3e-22 80.6 0.3 3.3e-16 59.7 0.1 2.9 2 1 0 2 2 2 2 MT-A70 PUF PF00806.19 KXG51039.1 - 1e-27 94.2 0.0 4e-05 23.1 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 KXG51039.1 - 2.5e-10 40.0 0.0 5.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 PF05764.13 KXG51040.1 - 7.7e-57 193.2 24.9 7.7e-57 193.2 24.9 2.8 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 KXG51040.1 - 7.8e-12 44.7 0.4 1.5e-11 43.8 0.4 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain BTD PF09270.10 KXG51041.1 - 0.0064 16.7 0.0 0.017 15.4 0.0 1.5 1 1 0 2 2 2 1 Beta-trefoil DNA-binding domain SKA2 PF16740.5 KXG51041.1 - 0.03 14.1 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 zf-C4H2 PF10146.9 KXG51041.1 - 0.099 12.9 0.2 0.12 12.7 0.2 1.2 1 1 0 1 1 1 0 Zinc finger-containing protein Ecl1 PF12855.7 KXG51042.1 - 9.7e-23 82.2 15.6 1.2e-22 81.9 15.6 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins SmpA_OmlA PF04355.13 KXG51042.1 - 0.044 13.6 0.0 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 SmpA / OmlA family BAR_3 PF16746.5 KXG51044.1 - 0.0065 16.2 0.0 0.0077 16.0 0.0 1.1 1 0 0 1 1 1 1 BAR domain of APPL family tRNA-synt_2 PF00152.20 KXG51045.1 - 1.3e-72 244.6 0.0 2e-72 243.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXG51045.1 - 5.8e-08 32.6 0.0 1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RRM_1 PF00076.22 KXG51046.1 - 9.4e-38 127.9 0.0 9.7e-12 44.5 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXG51046.1 - 1.6e-13 50.3 0.0 0.0012 18.7 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM PF10378.9 KXG51046.1 - 2.2e-09 36.9 0.8 1.9e-08 33.9 0.8 2.7 1 0 0 1 1 1 1 Putative RRM domain RRM_3 PF08777.11 KXG51046.1 - 0.00011 22.1 0.1 0.42 10.7 0.0 3.0 3 0 0 3 3 3 2 RNA binding motif DUF4523 PF15023.6 KXG51046.1 - 0.00024 21.0 0.0 0.47 10.3 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_Rrp7 PF17799.1 KXG51046.1 - 0.002 18.0 0.0 1.5 8.6 0.0 3.9 2 1 2 4 4 4 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KXG51046.1 - 0.0021 18.2 0.0 4 7.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif Iwr1 PF08574.10 KXG51047.1 - 1.7e-20 73.8 10.8 1.7e-20 73.8 10.8 2.5 3 0 0 3 3 3 1 Transcription factor Iwr1 KAR9 PF08580.10 KXG51048.1 - 1.6 7.2 13.3 1.9 6.9 13.3 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 CAP59_mtransfer PF11735.8 KXG51050.1 - 9e-78 261.3 0.0 1.4e-77 260.7 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF1349 PF07081.11 KXG51051.1 - 3e-28 98.8 0.0 3.9e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) MFS_1 PF07690.16 KXG51052.1 - 5.6e-21 74.8 42.4 1.4e-19 70.3 42.4 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Pox_A14 PF05767.12 KXG51052.1 - 0.19 11.9 2.7 0.2 11.8 0.1 2.4 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 Ras PF00071.22 KXG51053.1 - 4.3e-52 176.0 0.0 5.7e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXG51053.1 - 1.1e-18 67.6 0.0 1.5e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG51053.1 - 5.8e-06 25.9 0.0 7.8e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Arginase PF00491.21 KXG51054.1 - 8.9e-94 314.1 0.0 1.2e-93 313.7 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KXG51054.1 - 0.00071 19.8 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 UPF0489 domain ketoacyl-synt PF00109.26 KXG51055.1 - 7.3e-58 196.1 0.5 7.3e-58 196.1 0.5 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXG51055.1 - 8.7e-33 112.8 2.8 1.8e-32 111.8 1.9 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain SCA7 PF08313.12 KXG51055.1 - 6.9e-31 106.0 3.1 3e-30 103.9 0.8 2.7 2 0 0 2 2 2 1 SCA7, zinc-binding domain Thiolase_N PF00108.23 KXG51055.1 - 1.6e-05 24.4 1.8 0.00013 21.5 0.3 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXG51055.1 - 0.044 13.4 1.8 0.53 10.0 0.4 2.6 2 0 0 2 2 2 0 Thiolase, C-terminal domain CDC45 PF02724.14 KXG51055.1 - 1.3 7.3 12.3 1.9 6.7 12.3 1.2 1 0 0 1 1 1 0 CDC45-like protein mRNA_cap_enzyme PF01331.19 KXG51056.1 - 7.5e-53 179.3 0.1 1e-52 178.8 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KXG51056.1 - 1.3e-33 115.8 0.0 2.2e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KXG51056.1 - 1.8e-07 31.0 0.1 4.1e-06 26.6 0.1 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KXG51056.1 - 0.00041 20.7 0.0 0.031 14.6 0.0 2.2 2 0 0 2 2 2 1 RNA ligase MOZ_SAS PF01853.18 KXG51057.1 - 1.3e-79 266.0 0.0 1.9e-79 265.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 KXG51057.1 - 2.7e-23 81.6 0.0 5.6e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 KXG51057.1 - 2.7e-21 74.9 0.1 6e-21 73.8 0.1 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KXG51057.1 - 0.0045 17.4 0.0 0.009 16.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG51057.1 - 0.039 14.2 0.0 0.096 12.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family F1F0-ATPsyn_F PF10791.9 KXG51058.1 - 4.4e-40 136.0 0.1 1.1e-39 134.8 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi ETC_C1_NDUFA4 PF04800.12 KXG51059.1 - 1.8e-36 124.3 2.3 2.4e-36 123.8 2.3 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region HEAT_2 PF13646.6 KXG51060.1 - 4.1e-28 97.6 0.8 4e-12 46.3 0.0 3.6 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 KXG51060.1 - 1.3e-17 62.6 0.0 0.0045 17.5 0.0 6.3 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.22 KXG51060.1 - 1.1e-09 37.7 1.5 1 9.8 0.0 5.7 7 0 0 7 7 7 3 HEAT repeat Cnd1 PF12717.7 KXG51060.1 - 0.00061 19.9 0.0 0.17 11.9 0.0 2.9 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXG51060.1 - 0.0042 17.6 4.8 18 6.0 0.0 4.9 4 1 1 5 5 5 2 HEAT-like repeat Cohesin_HEAT PF12765.7 KXG51060.1 - 0.012 15.8 0.0 0.38 11.1 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion RuvA_C PF07499.13 KXG51060.1 - 0.11 13.0 3.4 6.6 7.3 0.3 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain Nipped-B_C PF12830.7 KXG51061.1 - 4.4e-48 163.7 2.2 2.8e-46 157.9 0.7 3.0 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KXG51061.1 - 9.5e-13 48.2 0.3 3.6e-12 46.4 0.3 2.1 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 KXG51061.1 - 3.6e-05 23.9 1.2 0.0053 16.8 0.0 3.7 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.7 KXG51061.1 - 0.00054 19.9 0.6 0.25 11.2 0.0 4.7 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT PF02985.22 KXG51061.1 - 0.0035 17.5 0.4 2 8.9 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat MA3 PF02847.17 KXG51061.1 - 0.005 16.8 0.1 3.9 7.5 0.0 3.6 3 0 0 3 3 3 1 MA3 domain CLAMP PF14769.6 KXG51061.1 - 0.11 13.0 0.1 0.4 11.1 0.1 1.9 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Pyr_redox_2 PF07992.14 KXG51062.1 - 7.3e-41 140.3 0.0 1e-40 139.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG51062.1 - 2e-12 47.5 0.0 1.6e-10 41.4 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KXG51062.1 - 3.4e-05 23.1 0.0 0.00015 21.0 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KXG51062.1 - 3.5e-05 24.1 0.0 7.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KXG51062.1 - 0.00036 20.2 0.1 0.001 18.8 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KXG51062.1 - 0.00072 18.9 0.2 0.0024 17.3 0.0 1.9 2 0 0 2 2 2 1 EF hand CLTH PF10607.9 KXG51063.1 - 1.6e-31 109.2 0.0 2.1e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KXG51063.1 - 1.5e-09 37.5 0.0 2.8e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 LisH HU-HIG PF18291.1 KXG51063.1 - 0.079 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 HU domain fused to wHTH, Ig, or Glycine-rich motif PRK PF00485.18 KXG51064.1 - 1.3e-46 158.8 0.1 1.9e-46 158.3 0.1 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KXG51064.1 - 1.3e-39 135.8 0.0 2.3e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KXG51064.1 - 0.098 12.2 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase domain NUC153 PF08159.12 KXG51065.1 - 1.1e-13 50.7 10.2 2.8e-12 46.2 1.0 3.8 3 0 0 3 3 3 2 NUC153 domain Spore_III_AF PF09581.10 KXG51065.1 - 3.3e-05 24.0 0.0 0.013 15.5 0.0 3.6 2 2 1 3 3 3 1 Stage III sporulation protein AF (Spore_III_AF) P5-ATPase PF12409.8 KXG51065.1 - 2.6 8.2 3.5 7.8 6.6 0.1 3.0 2 0 0 2 2 2 0 P5-type ATPase cation transporter FNIP_N PF14636.6 KXG51066.1 - 1.5e-29 103.9 0.8 1.5e-29 103.9 0.8 4.0 2 1 1 3 3 3 1 Folliculin-interacting protein N-terminus Glyco_hydro_31 PF01055.26 KXG51067.1 - 7.2e-114 381.4 2.1 9.1e-114 381.0 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXG51067.1 - 7.1e-19 67.9 0.0 4.7e-18 65.3 0.1 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like IML1 PF12257.8 KXG51068.1 - 7.3e-113 376.4 0.0 1e-112 375.9 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KXG51068.1 - 6.7e-28 96.6 0.7 1.2e-27 95.7 0.7 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MFS_1 PF07690.16 KXG51070.1 - 3.5e-36 124.9 27.1 3.5e-36 124.9 27.1 2.4 1 1 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KXG51070.1 - 9.3e-16 57.6 2.3 1.9e-15 56.7 2.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Herpes_UL32 PF06070.11 KXG51070.1 - 0.67 7.6 2.6 1 7.0 2.6 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Trp_syntA PF00290.20 KXG51071.1 - 1.7e-66 223.8 0.1 2.3e-66 223.3 0.1 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain MFS_1 PF07690.16 KXG51071.1 - 3.4e-20 72.3 31.7 5e-20 71.7 31.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Gpr1_Fun34_YaaH PF01184.19 KXG51072.1 - 9.3e-18 64.6 14.4 1.1e-14 54.5 9.3 2.1 1 1 1 2 2 2 2 GPR1/FUN34/yaaH family Pyr_redox_3 PF13738.6 KXG51073.1 - 4.9e-19 68.7 0.0 2.1e-16 60.0 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG51073.1 - 1.9e-14 53.6 0.0 5.5e-12 45.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXG51073.1 - 1.2e-13 50.3 0.3 6.7e-11 41.3 0.1 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXG51073.1 - 2.2e-10 40.2 0.1 3.4e-08 33.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXG51073.1 - 3.7e-06 27.1 0.0 2.2e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXG51073.1 - 1.5e-05 24.4 0.1 3.5e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXG51073.1 - 0.00025 21.5 0.9 1.6 9.3 0.1 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG51073.1 - 0.00081 18.6 0.1 0.0015 17.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXG51073.1 - 0.0011 17.8 0.1 0.0036 16.1 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KXG51073.1 - 0.017 14.4 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SnoaL_2 PF12680.7 KXG51073.1 - 0.018 15.6 0.0 0.054 14.1 0.0 1.8 1 0 0 1 1 1 0 SnoaL-like domain GIDA PF01134.22 KXG51073.1 - 0.027 13.6 0.4 0.33 10.0 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXG51073.1 - 0.027 13.8 0.1 0.059 12.7 0.1 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KXG51073.1 - 0.055 12.7 0.0 0.58 9.4 0.0 2.2 2 0 0 2 2 2 0 Thi4 family 2-Hacid_dh_C PF02826.19 KXG51073.1 - 0.11 11.8 0.0 0.7 9.2 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NTF2 PF02136.20 KXG51073.1 - 0.14 12.7 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain NAD_binding_10 PF13460.6 KXG51075.1 - 6e-19 68.7 0.0 7.5e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXG51075.1 - 4.3e-07 29.7 0.0 8e-07 28.8 0.0 1.4 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 KXG51075.1 - 0.00017 21.1 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 KXG51076.1 - 5.4e-19 68.2 0.0 9.3e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG51076.1 - 6.2e-05 23.0 7.6 0.00011 22.2 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_Ca_ex PF01699.24 KXG51077.1 - 6.3e-45 152.8 37.6 1.8e-23 83.1 17.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Vut_1 PF02592.15 KXG51077.1 - 0.0026 18.1 1.7 0.0026 18.1 1.7 3.2 3 2 1 4 4 4 1 Putative vitamin uptake transporter Glyco_hydro_72 PF03198.14 KXG51078.1 - 1e-130 435.6 7.0 1.3e-130 435.3 7.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KXG51078.1 - 2.8e-20 72.8 2.8 7.6e-20 71.4 2.8 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 KXG51078.1 - 0.00051 19.6 0.3 0.0014 18.1 0.3 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KXG51078.1 - 0.00099 18.3 1.9 0.0025 17.0 1.9 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Mannitol_dh_C PF08125.13 KXG51079.1 - 1.6e-71 240.6 0.0 2.3e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KXG51079.1 - 3.5e-43 147.3 0.0 6.3e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain GMC_oxred_N PF00732.19 KXG51080.1 - 6.5e-62 209.6 0.0 8.4e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG51080.1 - 1.4e-34 119.7 0.0 5.2e-34 117.8 0.0 2.0 3 0 0 3 3 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXG51080.1 - 1.3e-05 25.3 0.2 3.3e-05 24.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXG51080.1 - 4.8e-05 23.1 0.6 0.0053 16.4 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXG51080.1 - 7.4e-05 22.0 0.0 0.076 12.1 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KXG51080.1 - 0.00031 19.9 0.1 0.00055 19.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXG51080.1 - 0.00076 18.8 0.1 0.0084 15.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG51080.1 - 0.0026 17.0 0.2 0.057 12.7 0.1 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KXG51080.1 - 0.045 13.8 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXG51080.1 - 0.05 12.8 0.0 0.095 11.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KXG51080.1 - 0.054 12.7 0.4 10 5.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXG51080.1 - 0.083 13.2 0.0 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.14 KXG51080.1 - 0.17 10.6 0.4 0.3 9.7 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein PsiA PF06952.11 KXG51080.1 - 0.19 11.0 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 PsiA protein Alpha_L_fucos PF01120.17 KXG51082.1 - 1e-26 94.3 0.0 3.1e-26 92.7 0.0 1.6 1 1 1 2 2 2 1 Alpha-L-fucosidase F5_F8_type_C PF00754.25 KXG51082.1 - 0.0029 17.7 0.1 0.0079 16.3 0.1 1.7 1 0 0 1 1 1 1 F5/8 type C domain MFS_1 PF07690.16 KXG51084.1 - 5.2e-34 117.7 74.4 5.3e-33 114.4 49.0 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Aa_trans PF01490.18 KXG51085.1 - 1.3e-40 139.4 35.1 1.5e-40 139.1 35.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KXG51085.1 - 6.2e-06 25.5 14.1 6.2e-06 25.5 14.1 2.2 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family GWT1 PF06423.12 KXG51085.1 - 0.4 10.8 10.1 0.079 13.1 1.0 2.9 2 1 0 2 2 2 0 GWT1 MFS_1 PF07690.16 KXG51086.1 - 3.7e-32 111.6 30.4 5.1e-32 111.2 30.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXG51086.1 - 0.00012 21.5 8.1 0.00012 21.5 8.1 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Metallophos PF00149.28 KXG51087.1 - 2.2e-17 64.3 0.1 4.1e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KXG51087.1 - 2e-15 57.4 0.1 5.2e-15 56.0 0.1 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KXG51087.1 - 1.6e-13 51.0 1.1 3.5e-13 49.9 1.1 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 KXG51087.1 - 0.00019 21.9 0.1 0.00041 20.8 0.1 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain fn3 PF00041.21 KXG51087.1 - 0.06 13.7 0.4 0.11 12.8 0.4 1.4 1 0 0 1 1 1 0 Fibronectin type III domain GMC_oxred_N PF00732.19 KXG51089.1 - 1.6e-52 178.8 0.0 2.1e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG51089.1 - 1.7e-32 112.9 0.0 3.1e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXG51089.1 - 4.8e-05 22.6 0.0 7.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KXG51089.1 - 0.0017 17.5 0.0 0.12 11.4 0.0 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.24 KXG51089.1 - 0.0018 17.9 0.0 0.38 10.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG51089.1 - 0.0026 17.9 0.0 0.0058 16.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXG51089.1 - 0.0057 15.9 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG51089.1 - 0.011 15.0 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXG51089.1 - 0.15 10.7 0.0 1.2 7.8 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Fungal_trans PF04082.18 KXG51090.1 - 1.6e-15 56.8 2.6 2.7e-15 56.1 2.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhzC-PhzF PF02567.16 KXG51091.1 - 1.9e-38 132.6 0.0 2.2e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein p450 PF00067.22 KXG51092.1 - 3.3e-64 217.3 0.0 4.1e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_6 PF00970.24 KXG51093.1 - 2.6e-33 114.3 0.0 4.7e-33 113.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXG51093.1 - 1.5e-32 112.5 0.0 6.6e-32 110.4 0.0 2.1 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KXG51093.1 - 1.1e-23 83.1 0.0 2.3e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KXG51093.1 - 3.3e-05 24.1 0.0 0.00078 19.6 0.0 2.8 2 1 1 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KXG51093.1 - 0.016 15.4 0.0 1.3 9.2 0.0 2.6 2 1 1 3 3 3 0 Siderophore-interacting FAD-binding domain 3HCDH_N PF02737.18 KXG51094.1 - 2.7e-27 95.8 0.0 1.3e-26 93.6 0.0 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXG51094.1 - 4e-11 43.4 0.0 7.2e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain SGL PF08450.12 KXG51094.1 - 0.01 15.5 0.5 6.3 6.3 0.0 3.5 2 2 2 5 5 5 0 SMP-30/Gluconolactonase/LRE-like region Ldl_recept_b PF00058.17 KXG51094.1 - 0.018 15.5 0.0 13 6.3 0.0 4.0 4 0 0 4 4 4 0 Low-density lipoprotein receptor repeat class B ApbA PF02558.16 KXG51094.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lactonase PF10282.9 KXG51095.1 - 6.2e-83 278.9 0.0 7.4e-83 278.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller He_PIG PF05345.12 KXG51095.1 - 0.017 15.3 1.1 0.049 13.8 0.4 2.2 2 0 0 2 2 2 0 Putative Ig domain RP-C_C PF11800.8 KXG51096.1 - 0.52 10.4 4.2 0.44 10.6 0.3 2.3 3 0 0 3 3 3 0 Replication protein C C-terminal region GATase PF00117.28 KXG51097.1 - 0.00029 20.7 0.0 0.00043 20.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I TauD PF02668.16 KXG51098.1 - 3.6e-31 109.0 0.0 4.6e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cullin PF00888.22 KXG51099.1 - 8.2e-23 80.9 1.8 1.3e-22 80.2 1.8 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KXG51099.1 - 4.7e-22 78.3 0.1 2.4e-21 76.0 0.0 2.2 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Pkr1 PF08636.10 KXG51100.1 - 2.6e-30 104.4 5.5 3.3e-30 104.0 5.5 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Mem_trans PF03547.18 KXG51100.1 - 0.014 13.9 0.0 0.014 13.8 0.0 1.0 1 0 0 1 1 1 0 Membrane transport protein NEMP PF10225.9 KXG51100.1 - 0.021 14.5 0.1 0.025 14.3 0.1 1.1 1 0 0 1 1 1 0 NEMP family FHIPEP PF00771.20 KXG51100.1 - 0.17 10.3 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family Sugar_tr PF00083.24 KXG51101.1 - 7.3e-122 407.5 16.9 1.1e-121 406.9 16.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG51101.1 - 2.6e-27 95.7 31.1 9.1e-22 77.5 11.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ni_hydr_CYTB PF01292.20 KXG51101.1 - 1 9.0 17.0 0.3 10.6 6.4 2.6 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 NACHT PF05729.12 KXG51102.1 - 0.0006 19.8 0.0 0.00066 19.6 0.0 1.2 1 0 0 1 1 1 1 NACHT domain Nit_Regul_Hom PF10126.9 KXG51102.1 - 0.018 15.0 0.0 0.033 14.2 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII KAP_NTPase PF07693.14 KXG51102.1 - 0.037 13.3 0.3 0.049 12.9 0.3 1.2 1 0 0 1 1 1 0 KAP family P-loop domain F-box-like PF12937.7 KXG51103.1 - 0.00029 20.7 0.1 0.00084 19.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXG51103.1 - 0.014 15.3 0.1 0.037 13.9 0.1 1.7 1 0 0 1 1 1 0 F-box domain Glyco_hydro_15 PF00723.21 KXG51104.1 - 3.2e-50 171.2 0.0 4.3e-48 164.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 TPT PF03151.16 KXG51105.1 - 6.8e-22 78.2 16.8 8.5e-22 77.8 16.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXG51105.1 - 7.6e-05 22.9 34.6 0.001 19.2 14.3 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KXG51105.1 - 0.0034 16.6 18.4 0.0054 16.0 18.4 1.3 1 0 0 1 1 1 1 UAA transporter family Draxin PF15550.6 KXG51105.1 - 9.1 6.1 8.2 0.98 9.2 3.4 1.6 2 0 0 2 2 2 0 Draxin AP_endonuc_2 PF01261.24 KXG51106.1 - 5.5e-30 104.4 0.0 7.9e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Nuc_deoxyrib_tr PF05014.15 KXG51106.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Antigen_Bd37 PF11641.8 KXG51106.1 - 9.7 5.6 6.7 0.97 8.9 0.8 2.0 2 0 0 2 2 2 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Mad3_BUB1_I PF08311.12 KXG51107.1 - 3.6e-44 149.7 0.1 8.8e-44 148.5 0.0 1.7 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 KXG51107.1 - 1.4e-11 44.3 0.0 1.1e-10 41.5 0.0 2.5 3 0 0 3 3 3 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 KXG51107.1 - 9.5e-09 35.0 0.0 9.7e-08 31.7 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG51107.1 - 0.0045 16.3 0.0 0.012 14.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 KXG51107.1 - 0.045 13.9 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Kinase-like PF14531.6 KXG51107.1 - 0.084 12.2 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like p450 PF00067.22 KXG51109.1 - 1.4e-44 152.6 0.0 1.8e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C15 PF01470.17 KXG51110.1 - 1e-12 48.7 0.0 9e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Pyroglutamyl peptidase MOSC PF03473.17 KXG51111.1 - 3.2e-31 108.0 0.0 5.1e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXG51111.1 - 3.6e-22 78.5 0.0 2.1e-20 72.8 0.0 2.2 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain DNA_pol_phi PF04931.13 KXG51112.1 - 4.3e-256 851.9 24.6 5.3e-256 851.6 24.6 1.1 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 KXG51112.1 - 0.016 14.7 26.0 0.033 13.6 26.0 1.5 1 0 0 1 1 1 0 SDA1 RTP1_C1 PF10363.9 KXG51112.1 - 0.12 12.6 0.1 21 5.3 0.0 3.5 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Tub_N PF16322.5 KXG51112.1 - 3.4 8.0 12.6 15 6.0 12.6 2.1 1 0 0 1 1 1 0 Tubby N-terminal Rhodanese PF00581.20 KXG51113.1 - 1.2e-11 45.1 0.0 2.2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain CwfJ_C_1 PF04677.15 KXG51115.1 - 4e-24 84.8 0.0 1.4e-23 83.0 0.0 1.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KXG51115.1 - 4.8e-15 56.3 0.4 8.8e-15 55.4 0.4 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.12 KXG51116.1 - 1.7e-196 654.3 0.5 1.7e-196 654.3 0.5 4.5 5 0 0 5 5 5 1 Down-regulated in metastasis BP28CT PF08146.12 KXG51116.1 - 0.0042 16.9 0.1 0.049 13.5 0.0 3.0 2 0 0 2 2 2 1 BP28CT (NUC211) domain HEAT PF02985.22 KXG51116.1 - 0.011 15.9 6.3 0.12 12.7 0.0 6.1 7 0 0 7 7 7 0 HEAT repeat Arm_2 PF04826.13 KXG51116.1 - 0.041 13.3 0.1 0.25 10.8 0.0 2.1 2 0 0 2 2 2 0 Armadillo-like MMS19_C PF12460.8 KXG51116.1 - 3.7 6.6 15.1 3.5 6.6 0.0 5.2 5 1 0 5 5 5 0 RNAPII transcription regulator C-terminal zf-DNL PF05180.12 KXG51117.1 - 2.9e-28 97.6 0.8 4.4e-28 97.0 0.8 1.3 1 0 0 1 1 1 1 DNL zinc finger TFIIS_C PF01096.18 KXG51117.1 - 0.0042 16.9 3.6 0.17 11.8 0.8 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) zf-CSL PF05207.13 KXG51117.1 - 0.0082 15.8 0.4 0.015 15.0 0.4 1.4 1 0 0 1 1 1 1 CSL zinc finger Elf1 PF05129.13 KXG51117.1 - 0.011 15.8 0.2 0.018 15.1 0.2 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 KXG51117.1 - 0.034 14.3 0.7 0.074 13.2 0.7 1.5 1 0 0 1 1 1 0 Zinc ribbon domain TIP41 PF04176.13 KXG51117.1 - 0.035 13.6 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 TIP41-like family HypA PF01155.19 KXG51117.1 - 0.065 13.3 0.6 0.1 12.6 0.6 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 KXG51117.1 - 0.082 13.3 0.4 16 5.9 0.0 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-LSD1 PF06943.12 KXG51117.1 - 0.15 11.9 0.7 0.86 9.5 0.2 2.1 2 0 0 2 2 2 0 LSD1 zinc finger DNA_RNApol_7kD PF03604.13 KXG51117.1 - 0.29 10.8 1.3 4.6 7.0 0.3 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit E7 PF00527.18 KXG51117.1 - 0.38 11.0 4.4 2.8 8.2 4.4 2.2 1 1 0 1 1 1 0 E7 protein, Early protein Zn_Tnp_IS1595 PF12760.7 KXG51117.1 - 4.5 7.3 7.3 24 5.0 0.5 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Cullin PF00888.22 KXG51118.1 - 8.9e-200 665.4 9.3 8.9e-200 665.4 9.3 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KXG51118.1 - 1.4e-25 89.1 1.0 1.4e-25 89.1 1.0 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain SLD5_C PF16922.5 KXG51119.1 - 2.2e-14 53.4 0.8 3.5e-14 52.7 0.8 1.3 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KXG51119.1 - 1.5e-09 38.3 0.3 2.6e-09 37.5 0.3 1.4 1 1 0 1 1 1 1 GINS complex protein RCR PF12273.8 KXG51120.1 - 7.7e-21 75.0 14.3 9.4e-21 74.7 14.3 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF2157 PF09925.9 KXG51120.1 - 0.076 12.8 0.0 0.076 12.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) SARAF PF06682.12 KXG51120.1 - 2.9 7.5 5.3 0.65 9.6 2.1 1.5 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Peptidase_S10 PF00450.22 KXG51122.1 - 8.5e-110 368.0 1.2 9.9e-110 367.8 1.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.16 KXG51123.1 - 2.4e-16 59.6 30.3 3.5e-16 59.1 30.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXG51123.1 - 1.5e-10 41.0 4.9 1.5e-10 41.0 4.9 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 KXG51123.1 - 0.0012 17.8 6.3 0.0012 17.8 6.3 2.3 1 1 1 2 2 2 1 MFS_1 like family ABC2_membrane_5 PF13346.6 KXG51123.1 - 4.5 6.8 17.9 0.035 13.6 6.4 2.7 2 1 1 3 3 3 0 ABC-2 family transporter protein Amidohydro_1 PF01979.20 KXG51124.1 - 2e-14 53.7 0.0 2.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXG51124.1 - 1e-09 38.4 1.5 2.8e-07 30.4 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family GMC_oxred_N PF00732.19 KXG51125.1 - 4.8e-53 180.5 0.0 6.1e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG51125.1 - 2.3e-36 125.5 0.0 3.4e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXG51125.1 - 3.9e-07 29.5 0.2 0.01 14.9 0.1 2.4 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.12 KXG51125.1 - 0.00038 19.6 0.0 0.00056 19.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXG51125.1 - 0.00054 20.1 0.1 0.0018 18.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXG51125.1 - 0.0018 17.9 0.3 0.051 13.2 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG51125.1 - 0.009 15.3 0.0 0.037 13.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG51125.1 - 0.03 14.9 0.3 1.6 9.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG51125.1 - 0.037 13.3 0.1 0.72 9.1 0.0 2.5 3 0 0 3 3 3 0 Thi4 family FAD_oxidored PF12831.7 KXG51125.1 - 0.049 13.0 0.2 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KXG51125.1 - 0.2 10.7 0.2 1.5 7.8 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Aldedh PF00171.22 KXG51126.1 - 2.5e-157 524.1 0.3 2.9e-157 523.9 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glucosamine_iso PF01182.20 KXG51127.1 - 2.5e-20 73.4 0.0 3.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.21 KXG51128.1 - 3.8e-67 226.9 0.0 5e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 KXG51128.1 - 0.00049 20.3 0.0 0.0016 18.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 KXG51128.1 - 0.004 17.1 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_6 PF13480.7 KXG51128.1 - 0.075 13.2 0.0 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain NDT80_PhoG PF05224.12 KXG51129.1 - 1.5e-41 142.7 0.0 3.1e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family CPSF_A PF03178.15 KXG51130.1 - 1.6e-104 349.7 0.0 4.2e-104 348.3 0.0 1.8 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 KXG51130.1 - 4.7e-19 68.4 0.0 6e-18 64.7 0.0 2.3 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.16 KXG51131.1 - 3e-19 69.3 25.1 9.3e-17 61.1 22.6 2.5 2 1 0 2 2 2 1 LMBR1-like membrane protein Anemone_cytotox PF06369.12 KXG51131.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Sea anemone cytotoxic protein TMIE PF16038.5 KXG51131.1 - 0.15 11.9 0.2 0.88 9.4 0.0 2.3 2 0 0 2 2 2 0 TMIE protein Zip PF02535.22 KXG51132.1 - 4.7e-48 164.1 0.0 7.5e-48 163.5 0.0 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter PsbH PF00737.20 KXG51132.1 - 7.1 6.5 6.3 0.67 9.7 0.8 2.1 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Thiolase_N PF00108.23 KXG51133.1 - 9.4e-92 307.0 0.8 1.2e-91 306.7 0.4 1.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXG51133.1 - 2e-43 147.0 2.6 2.5e-43 146.7 1.4 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXG51133.1 - 8.5e-07 28.8 1.2 2.7e-06 27.1 0.6 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXG51133.1 - 0.07 13.0 2.0 0.31 10.9 0.1 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.27 KXG51134.1 - 3.7e-46 157.1 0.0 5.7e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KXG51134.1 - 8.4e-38 129.7 11.8 1.5e-37 128.9 11.8 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KXG51134.1 - 1.2e-23 83.2 0.0 3.1e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KXG51134.1 - 7.5e-20 70.8 0.0 2e-19 69.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXG51134.1 - 6.3e-12 45.7 0.0 1.5e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXG51134.1 - 1.6e-07 31.3 0.2 1.4e-06 28.3 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KXG51134.1 - 1.1e-06 28.7 0.1 2e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KXG51134.1 - 0.0068 16.0 0.0 0.036 13.7 0.0 2.1 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 KXG51134.1 - 0.19 11.1 0.2 4.3 6.7 0.1 2.7 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit FeS_assembly_P PF01883.19 KXG51135.1 - 7.6e-09 35.6 0.0 2.1e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Fungal_trans PF04082.18 KXG51136.1 - 4.9e-05 22.5 0.4 7.9e-05 21.8 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HSP70 PF00012.20 KXG51138.1 - 8.1e-222 737.6 6.5 8.1e-222 737.6 6.5 2.1 2 0 0 2 2 2 1 Hsp70 protein RRF PF01765.19 KXG51138.1 - 3.4e-44 150.6 1.7 3.4e-44 150.6 1.7 2.6 4 0 0 4 4 4 1 Ribosome recycling factor MreB_Mbl PF06723.13 KXG51138.1 - 4.5e-16 58.6 0.6 1.3e-15 57.0 0.2 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KXG51138.1 - 0.00055 19.7 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain PilJ PF13675.6 KXG51138.1 - 0.065 13.3 1.6 0.22 11.5 1.6 1.9 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term PcfJ PF14284.6 KXG51138.1 - 0.17 11.8 1.7 0.36 10.7 1.7 1.6 1 0 0 1 1 1 0 PcfJ-like protein tRNA-synt_2c PF01411.19 KXG51140.1 - 1.3e-216 720.4 0.0 1.9e-216 719.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KXG51140.1 - 2.1e-17 62.9 0.6 4.6e-17 61.8 0.6 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KXG51140.1 - 2.4e-11 44.2 2.6 2.4e-11 44.2 2.6 2.2 2 0 0 2 2 2 1 DHHA1 domain Rad4 PF03835.15 KXG51140.1 - 0.079 12.6 0.6 0.16 11.7 0.6 1.5 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain Pro_isomerase PF00160.21 KXG51141.1 - 2.5e-49 167.6 0.8 2.8e-49 167.4 0.8 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-RING_2 PF13639.6 KXG51142.1 - 4.9e-12 46.0 6.9 8.1e-12 45.3 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXG51142.1 - 1.3e-08 34.6 6.0 2.1e-08 33.8 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXG51142.1 - 1.6e-08 34.1 1.9 2.8e-08 33.4 1.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXG51142.1 - 5e-08 32.7 4.4 8.2e-08 32.0 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXG51142.1 - 3.5e-06 26.9 3.6 5.9e-06 26.1 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXG51142.1 - 7.2e-06 26.2 10.1 3.2e-05 24.1 10.1 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXG51142.1 - 0.00023 21.1 1.1 0.00023 21.1 1.1 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXG51142.1 - 0.0022 17.8 2.8 0.0038 17.1 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXG51142.1 - 0.0024 17.9 3.1 0.0061 16.6 3.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXG51142.1 - 0.01 15.4 3.4 0.019 14.5 3.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KXG51142.1 - 0.09 12.6 6.6 0.16 11.8 6.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KXG51142.1 - 0.11 12.4 5.7 0.24 11.3 5.7 1.6 1 0 0 1 1 1 0 PHD-finger OAD_gamma PF04277.13 KXG51142.1 - 0.2 12.3 0.0 0.62 10.7 0.0 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain zf-C3HC4_4 PF15227.6 KXG51142.1 - 0.21 11.8 5.0 0.47 10.7 5.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXG51142.1 - 0.37 10.7 6.0 1.1 9.2 6.0 1.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 KXG51142.1 - 0.45 10.6 3.5 1.2 9.2 3.5 1.7 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 KXG51142.1 - 0.59 10.3 4.1 1.4 9.1 4.1 1.7 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KXG51142.1 - 0.62 10.3 3.6 1.8 8.8 3.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 KXG51142.1 - 5.6 7.0 8.6 0.19 11.7 1.4 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF3844 PF12955.7 KXG51143.1 - 1.5e-35 121.5 5.2 2.7e-35 120.6 5.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) CKS PF01111.19 KXG51145.1 - 7.7e-35 119.0 0.5 7.7e-35 119.0 0.5 1.4 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit Bromodomain PF00439.25 KXG51146.1 - 8.2e-15 54.6 0.0 1.5e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain RRM_1 PF00076.22 KXG51147.1 - 8.1e-33 112.1 0.0 7.4e-16 57.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXG51147.1 - 0.00077 19.1 0.0 0.14 11.7 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXG51147.1 - 0.0015 18.6 0.0 0.0093 16.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 KXG51147.1 - 0.0093 15.6 0.1 0.34 10.6 0.1 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain Limkain-b1 PF11608.8 KXG51147.1 - 0.013 15.6 0.1 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 RRM_occluded PF16842.5 KXG51147.1 - 0.081 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KXG51147.1 - 0.091 13.0 0.1 9 6.5 0.0 2.3 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Cas_Cas2CT1978 PF09707.10 KXG51147.1 - 0.12 12.5 0.0 5 7.3 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) DUF2015 PF09435.10 KXG51148.1 - 1.7e-47 159.9 0.0 2.1e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.17 KXG51149.1 - 2e-23 83.3 1.9 6.5e-23 81.7 1.9 1.8 1 1 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_N PF00056.23 KXG51150.1 - 5.9e-45 152.8 0.1 8.5e-45 152.3 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KXG51150.1 - 1e-44 152.4 0.0 1.4e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KXG51150.1 - 6e-05 22.2 0.0 8.8e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TRAPP PF04051.16 KXG51151.1 - 4.6e-43 146.4 0.0 5.7e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PorB PF11565.8 KXG51151.1 - 0.0038 17.6 0.0 0.18 12.3 0.0 2.2 2 0 0 2 2 2 1 Alpha helical Porin B PINIT PF14324.6 KXG51152.1 - 2.4e-39 135.0 0.5 5.2e-39 133.9 0.5 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KXG51152.1 - 2.8e-22 78.2 7.1 4.9e-22 77.4 7.1 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KXG51152.1 - 3.3e-07 30.0 3.0 8.4e-07 28.7 3.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KXG51152.1 - 0.00034 20.3 0.8 0.00058 19.6 0.1 1.8 2 0 0 2 2 2 1 SAP domain Prok-RING_4 PF14447.6 KXG51152.1 - 0.086 12.7 3.7 0.18 11.7 3.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FYVE_2 PF02318.16 KXG51152.1 - 0.15 12.3 1.3 0.26 11.5 1.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.6 KXG51152.1 - 2.2 8.5 5.2 4.3 7.6 5.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2423 PF10338.9 KXG51153.1 - 7.4e-21 74.1 0.9 7.4e-21 74.1 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Mitoc_L55 PF09776.9 KXG51153.1 - 2.9 7.7 6.2 1 9.1 0.2 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L55 Phosphodiest PF01663.22 KXG51154.1 - 3.2e-12 46.7 3.0 2.7e-07 30.5 0.4 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXG51154.1 - 1e-05 25.1 0.0 8.3e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Sulfatase DUF229 PF02995.17 KXG51154.1 - 0.13 10.9 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) PT PF04886.12 KXG51155.1 - 0.0042 16.6 3.7 0.0084 15.6 3.7 1.4 1 0 0 1 1 1 1 PT repeat Peptidase_S8_N PF16361.5 KXG51155.1 - 0.24 11.9 3.0 0.53 10.8 2.5 1.8 2 0 0 2 2 2 0 N-terminal of Subtilase family RRM_2 PF04059.12 KXG51156.1 - 2.3e-31 107.8 0.0 3.8e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 KXG51156.1 - 4.9e-05 23.1 0.0 0.061 13.1 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec15 PF04091.12 KXG51157.1 - 2.1e-107 359.2 1.3 2.1e-107 359.2 1.3 1.7 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 KXG51157.1 - 2.8e-05 24.0 1.9 0.00012 21.9 0.8 2.6 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG5 PF10392.9 KXG51157.1 - 0.00097 19.3 4.7 0.0025 18.0 2.6 2.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 COG2 PF06148.11 KXG51157.1 - 0.0015 18.6 1.5 0.0015 18.6 1.5 2.9 3 1 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec5 PF15469.6 KXG51157.1 - 0.011 15.6 6.5 0.033 14.0 2.3 2.9 3 0 0 3 3 3 0 Exocyst complex component Sec5 DUF3510 PF12022.8 KXG51157.1 - 0.015 15.7 4.5 1.3 9.4 0.0 3.7 2 2 2 4 4 4 0 Domain of unknown function (DUF3510) Vps51 PF08700.11 KXG51157.1 - 0.033 14.3 1.6 0.16 12.1 0.2 2.7 2 0 0 2 2 2 0 Vps51/Vps67 Mre11_DNA_bind PF04152.14 KXG51157.1 - 0.068 13.5 0.9 0.32 11.3 0.0 2.5 2 0 0 2 2 2 0 Mre11 DNA-binding presumed domain ApoLp-III PF07464.11 KXG51157.1 - 0.4 10.8 6.7 2.3 8.3 0.4 3.3 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Vps54_N PF10475.9 KXG51157.1 - 1.6 7.9 8.4 0.098 11.9 2.5 1.9 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Fcf2 PF08698.11 KXG51158.1 - 8.1e-37 125.5 0.8 8.1e-37 125.5 0.8 2.1 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing PNP_UDP_1 PF01048.20 KXG51159.1 - 5.4e-47 160.0 0.1 8.1e-47 159.4 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily tRNA-synt_1b PF00579.25 KXG51160.1 - 1.7e-54 185.2 0.0 2.5e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_S10 PF00338.22 KXG51160.1 - 1.8e-27 95.4 0.0 4.7e-27 94.1 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DAHP_synth_1 PF00793.20 KXG51160.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 DAHP synthetase I family FAP PF07174.11 KXG51160.1 - 1.9 7.9 22.5 2.8 7.3 22.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Asp PF00026.23 KXG51161.1 - 2.6e-72 243.9 6.8 3.1e-72 243.6 6.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXG51161.1 - 2.1e-13 50.9 4.8 9.2e-12 45.6 4.8 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXG51161.1 - 2.3e-06 28.2 0.4 0.12 13.0 0.0 4.2 4 1 1 5 5 5 2 Aspartyl protease TAXi_C PF14541.6 KXG51161.1 - 0.1 12.4 0.1 1 9.1 0.0 2.5 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal MTS PF05175.14 KXG51162.1 - 8.9e-08 31.9 0.0 0.00011 21.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 KXG51162.1 - 1.3e-06 28.3 0.0 2.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG51162.1 - 9.6e-06 26.2 0.0 1.8e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG51162.1 - 0.00035 20.5 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 KXG51162.1 - 0.0025 17.2 0.0 0.093 12.0 0.0 2.1 2 0 0 2 2 2 1 RNA methyltransferase Ubie_methyltran PF01209.18 KXG51162.1 - 0.0034 16.7 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AviRa PF11599.8 KXG51162.1 - 0.0061 16.0 0.0 0.02 14.4 0.0 1.9 1 1 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_12 PF08242.12 KXG51162.1 - 0.012 16.4 0.0 0.022 15.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KXG51162.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KXG51162.1 - 0.034 14.8 0.0 0.059 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KXG51162.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase FA_hydroxylase PF04116.13 KXG51163.1 - 8.7e-24 84.4 15.7 8.7e-24 84.4 15.7 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily WD40 PF00400.32 KXG51164.1 - 2.9e-63 208.3 11.1 1.8e-09 38.0 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG51164.1 - 5.6e-21 74.6 0.0 0.00033 20.9 0.0 6.5 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 KXG51164.1 - 1.6e-18 66.8 10.0 2.7e-18 66.0 10.0 1.4 1 0 0 1 1 1 1 Tup N-terminal WD40_like PF17005.5 KXG51164.1 - 2.6e-07 30.3 0.0 0.34 10.2 0.0 4.3 4 1 2 6 6 6 3 WD40-like domain Ge1_WD40 PF16529.5 KXG51164.1 - 7.8e-07 28.3 0.1 0.22 10.5 0.0 4.9 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KXG51164.1 - 1.6e-05 23.6 1.0 0.00026 19.7 0.2 2.5 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 KXG51164.1 - 5.5e-05 22.0 0.1 0.3 9.7 0.0 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KXG51164.1 - 0.00039 20.3 0.0 0.025 14.5 0.0 2.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KXG51164.1 - 0.034 13.5 0.0 6.1 6.1 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KXG51164.1 - 0.067 13.1 0.0 12 6.0 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat UPF0242 PF06785.11 KXG51164.1 - 0.69 10.0 6.7 1.1 9.4 6.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPX2 PF06886.11 KXG51164.1 - 0.79 10.0 6.0 1.6 9.0 6.0 1.5 1 1 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) zf-C2H2 PF00096.26 KXG51165.1 - 4e-19 67.9 21.5 0.00015 22.0 0.7 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXG51165.1 - 3.4e-11 43.0 19.2 0.0097 16.7 0.9 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXG51165.1 - 6.6e-11 42.1 33.5 1.7e-08 34.5 2.3 5.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_8 PF15909.5 KXG51165.1 - 4.2e-05 23.8 8.0 0.00063 20.0 3.4 3.4 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KXG51165.1 - 0.0001 22.5 4.4 0.057 13.6 0.1 3.2 2 1 1 3 3 3 2 Aberrant zinc-finger zf-met PF12874.7 KXG51165.1 - 0.0032 17.8 10.9 0.059 13.8 0.4 4.8 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-DNA_Pol PF08996.10 KXG51165.1 - 0.13 12.0 6.2 1.1 9.0 1.4 2.4 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-C2H2_6 PF13912.6 KXG51165.1 - 0.99 9.5 16.6 4.7 7.3 0.6 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger MIF4G_like PF09088.11 KXG51166.1 - 6.7e-88 293.5 0.2 1.1e-87 292.8 0.2 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KXG51166.1 - 6.6e-76 255.3 0.0 1.1e-75 254.6 0.0 1.4 1 0 0 1 1 1 1 MIF4G like DUF5448 PF17526.2 KXG51166.1 - 0.011 15.9 0.0 0.99 9.6 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5448) DUF2326 PF10088.9 KXG51166.1 - 0.26 11.0 0.9 1.5 8.6 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein conserved in bacteria (DUF2326) Pkinase PF00069.25 KXG51167.1 - 2.9e-66 223.5 0.0 3.4e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG51167.1 - 1.3e-24 86.8 0.0 1.7e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG51167.1 - 8e-06 25.4 0.0 3.7e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXG51167.1 - 0.00079 19.4 0.3 0.022 14.7 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KXG51167.1 - 0.19 11.0 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Porin_3 PF01459.22 KXG51168.1 - 9.2e-82 274.5 0.1 1.1e-81 274.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.10 KXG51168.1 - 0.047 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term 6PF2K PF01591.18 KXG51169.1 - 5.5e-63 212.2 0.1 8e-63 211.7 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXG51169.1 - 3.8e-20 72.4 0.7 1.8e-19 70.2 0.7 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KXG51169.1 - 0.019 15.1 0.0 0.052 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 KXG51169.1 - 0.077 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 KXG51169.1 - 0.13 12.1 0.0 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase Urm1 PF09138.11 KXG51170.1 - 1.3e-35 121.7 0.1 1.4e-35 121.5 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KXG51170.1 - 0.00038 21.0 0.0 0.00047 20.7 0.0 1.1 1 0 0 1 1 1 1 ThiS family WD40 PF00400.32 KXG51171.1 - 1.5e-31 107.9 28.2 4.7e-06 27.2 0.1 12.0 12 0 0 12 12 12 8 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXG51171.1 - 1.2e-05 24.5 0.4 0.35 9.8 0.0 4.1 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KXG51171.1 - 7.9e-05 22.9 9.8 33 4.9 0.0 7.9 7 2 2 9 9 9 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KXG51171.1 - 0.0016 18.5 0.2 27 4.9 0.0 5.6 6 1 0 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Albumin_I_a PF16720.5 KXG51172.1 - 0.075 12.9 0.2 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 Albumin I chain a Fungal_trans PF04082.18 KXG51173.1 - 9.3e-10 38.0 0.5 2e-09 36.9 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.21 KXG51174.1 - 1.1e-106 357.6 0.0 1.4e-106 357.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Rep_fac_C PF08542.11 KXG51175.1 - 3.1e-22 78.8 0.0 1.7e-21 76.4 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KXG51175.1 - 2.4e-12 46.9 0.0 4.1e-09 36.4 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 KXG51175.1 - 5.4e-11 43.0 0.0 9.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KXG51175.1 - 7.2e-07 29.3 0.0 3e-06 27.3 0.0 2.0 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 KXG51175.1 - 5.5e-06 26.9 0.0 0.00045 20.6 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXG51175.1 - 3.8e-05 23.5 0.0 8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KXG51175.1 - 0.00013 21.8 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KXG51175.1 - 0.00014 21.7 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KXG51175.1 - 0.00024 21.4 0.1 0.61 10.4 0.1 2.4 1 1 1 2 2 2 2 AAA domain DNA_pol3_delta PF06144.13 KXG51175.1 - 0.0008 19.2 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 KXG51175.1 - 0.0056 16.1 0.0 0.055 12.9 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 KXG51175.1 - 0.0062 16.0 0.0 3.9 6.9 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein Rad17 PF03215.15 KXG51175.1 - 0.0082 16.1 0.0 0.015 15.2 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 KXG51175.1 - 0.0083 15.9 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KXG51175.1 - 0.0098 14.9 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_assoc_2 PF16193.5 KXG51175.1 - 0.025 14.9 0.0 0.079 13.3 0.0 1.9 2 0 0 2 2 1 0 AAA C-terminal domain AAA_19 PF13245.6 KXG51175.1 - 0.03 14.7 0.2 0.078 13.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KXG51175.1 - 0.03 14.2 0.3 0.15 12.0 0.2 2.1 1 1 1 2 2 2 0 NTPase KTI12 PF08433.10 KXG51175.1 - 0.035 13.6 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_25 PF13481.6 KXG51175.1 - 0.051 13.1 0.1 0.25 10.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXG51175.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KXG51175.1 - 0.056 13.2 0.1 1.7 8.4 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.6 KXG51175.1 - 0.057 13.1 0.2 0.15 11.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain RGS12_usC PF16612.5 KXG51175.1 - 0.18 12.3 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 C-terminal unstructured region of RGS12 Imm49 PF15575.6 KXG51176.1 - 0.014 15.2 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 49 DUF410 PF04190.13 KXG51177.1 - 4e-88 295.5 0.0 4.8e-88 295.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RAI1 PF08652.11 KXG51178.1 - 1.3e-27 95.7 0.0 2.6e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease IPPT PF01715.17 KXG51179.1 - 3.4e-60 203.7 0.4 5.2e-60 203.1 0.4 1.2 1 0 0 1 1 1 1 IPP transferase zf-met PF12874.7 KXG51179.1 - 3.6e-07 30.4 1.6 8.6e-07 29.2 1.6 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXG51179.1 - 1.7e-05 25.0 3.8 3.2e-05 24.1 3.8 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXG51179.1 - 0.0073 16.6 2.3 0.057 13.8 2.2 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KXG51179.1 - 0.038 14.8 0.7 0.082 13.8 0.7 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Ring_hydroxyl_A PF00848.19 KXG51179.1 - 0.047 13.7 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) zf-C2H2_6 PF13912.6 KXG51179.1 - 0.29 11.2 3.6 0.49 10.4 3.6 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger ABC_tran PF00005.27 KXG51180.1 - 1e-16 61.7 0.1 9.1e-16 58.6 0.1 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXG51180.1 - 4.8e-11 43.0 1.2 3.2e-05 23.9 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXG51180.1 - 0.0012 18.3 0.0 0.54 9.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXG51180.1 - 0.0017 18.1 0.2 0.0031 17.2 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXG51180.1 - 0.0021 18.0 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 KXG51180.1 - 0.0022 17.6 0.1 0.0044 16.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain DUF3584 PF12128.8 KXG51180.1 - 0.0034 15.0 0.4 0.0047 14.5 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_23 PF13476.6 KXG51180.1 - 0.0072 16.8 0.1 0.011 16.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KXG51180.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 KXG51180.1 - 0.011 16.0 0.2 0.028 14.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KXG51180.1 - 0.016 14.9 0.1 0.024 14.4 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 KXG51180.1 - 0.03 14.7 1.2 0.074 13.4 1.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 KXG51180.1 - 0.039 14.2 0.0 0.091 13.0 0.0 1.6 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 KXG51180.1 - 0.049 14.1 0.3 0.28 11.6 0.3 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXG51180.1 - 0.056 13.7 0.4 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 KXG51180.1 - 0.078 12.4 0.2 0.17 11.3 0.2 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_33 PF13671.6 KXG51180.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 KXG51180.1 - 0.13 10.9 0.1 0.17 10.5 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXG51180.1 - 0.13 12.3 0.1 0.85 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KXG51180.1 - 0.16 12.0 0.0 0.61 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 KXG51180.1 - 0.17 10.7 0.1 0.28 9.9 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) SRP54 PF00448.22 KXG51180.1 - 0.2 11.3 0.1 0.32 10.6 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Sugar_tr PF00083.24 KXG51181.1 - 6.2e-86 289.0 11.7 7e-86 288.9 11.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG51181.1 - 8.3e-23 80.9 11.2 8.3e-23 80.9 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_32N PF00251.20 KXG51182.1 - 9.1e-43 146.9 0.0 1.4e-42 146.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KXG51182.1 - 1.6e-26 93.2 0.0 2.3e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.20 KXG51182.1 - 0.019 14.9 3.8 0.13 12.3 0.0 3.5 3 0 0 3 3 3 0 BNR/Asp-box repeat CC2D2AN-C2 PF15625.6 KXG51182.1 - 0.033 13.9 0.0 1.8 8.3 0.0 2.7 3 0 0 3 3 3 0 CC2D2A N-terminal C2 domain DUF4975 PF16346.5 KXG51182.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) AA_permease_2 PF13520.6 KXG51183.1 - 1.4e-61 208.7 38.9 2.5e-61 207.8 38.9 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG51183.1 - 1.7e-26 92.9 22.9 1.7e-26 92.9 22.9 2.1 2 0 0 2 2 2 1 Amino acid permease DUF1673 PF07895.11 KXG51183.1 - 0.27 10.9 1.9 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) NAD_binding_1 PF00175.21 KXG51184.1 - 1e-08 35.8 0.0 0.0058 17.3 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXG51184.1 - 0.00019 21.8 0.0 0.00062 20.1 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXG51184.1 - 0.0026 17.9 0.0 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Aminotran_5 PF00266.19 KXG51185.1 - 1.2e-28 100.2 0.0 4.1e-18 65.5 0.0 2.1 1 1 0 2 2 2 2 Aminotransferase class-V DUF4328 PF14219.6 KXG51185.1 - 0.059 12.9 0.1 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) HscB_4_cys PF18256.1 KXG51186.1 - 0.055 13.3 1.1 0.055 13.3 1.1 2.4 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Inhibitor_I67 PF11405.8 KXG51186.1 - 1.3 9.3 6.6 1 9.7 0.4 2.9 3 0 0 3 3 3 0 Bromelain inhibitor VI TrmE_N PF10396.9 KXG51187.1 - 2.9e-37 127.5 0.0 5.7e-37 126.6 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 KXG51187.1 - 1.5e-26 93.8 0.0 3.9e-26 92.5 0.0 1.7 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 KXG51187.1 - 1.1e-17 64.1 0.1 1.8e-17 63.5 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXG51187.1 - 8e-05 22.2 0.1 0.00022 20.8 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXG51187.1 - 0.00016 21.7 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.27 KXG51187.1 - 0.00026 20.6 0.0 0.02 14.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KXG51187.1 - 0.0041 16.9 0.0 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 KXG51187.1 - 0.13 12.4 0.1 0.4 10.9 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KXG51187.1 - 0.16 11.8 0.2 0.71 9.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Trp_ring PF18669.1 KXG51187.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.6 3 0 0 3 3 3 0 Trimeric autotransporter adhesin Trp ring domain FH2 PF02181.23 KXG51188.1 - 3.6e-90 302.8 2.4 3.6e-90 302.8 2.4 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KXG51188.1 - 5.5e-68 228.2 0.5 1.5e-67 226.8 0.0 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KXG51188.1 - 1.4e-52 178.1 0.6 5.2e-51 173.0 0.1 2.7 1 1 1 2 2 2 2 Diaphanous FH3 Domain 2-Hacid_dh_C PF02826.19 KXG51190.1 - 1.6e-51 174.2 0.0 2.9e-51 173.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXG51190.1 - 8.3e-16 57.9 0.0 1.1e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXG51190.1 - 0.00037 20.7 0.0 0.00087 19.5 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KXG51190.1 - 0.0053 16.1 0.1 0.3 10.4 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Suc_Fer-like PF06999.12 KXG51191.1 - 1.4e-58 198.0 0.0 2.5e-58 197.2 0.0 1.4 1 0 0 1 1 1 1 Sucrase/ferredoxin-like tRNA-synt_1 PF00133.22 KXG51191.1 - 2.1e-53 181.6 0.0 2.9e-35 121.6 0.0 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KXG51191.1 - 4.8e-39 133.8 0.0 7.5e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KXG51191.1 - 1.6e-26 93.0 0.2 8e-20 70.9 0.0 4.2 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KXG51191.1 - 4.2e-09 36.5 0.0 9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.19 KXG51191.1 - 0.0052 15.8 0.0 0.0087 15.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) adh_short PF00106.25 KXG51192.1 - 4.6e-32 111.1 0.0 6.2e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG51192.1 - 2.1e-21 76.6 0.0 2.5e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG51192.1 - 1.3e-10 41.5 0.0 1.8e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXG51192.1 - 4.8e-06 26.2 0.1 9.6e-06 25.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXG51192.1 - 0.00097 18.3 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXG51192.1 - 0.0014 17.8 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KXG51192.1 - 0.0044 16.9 0.0 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KXG51192.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 KXG51192.1 - 0.019 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.19 KXG51192.1 - 0.044 12.8 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXG51192.1 - 0.14 11.3 0.0 16 4.6 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein Sec1 PF00995.23 KXG51193.1 - 5.7e-134 448.5 0.0 6.6e-134 448.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_tran_WecB PF03808.13 KXG51193.1 - 0.059 13.3 0.0 0.96 9.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family MBOAT PF03062.19 KXG51194.1 - 1.6e-54 185.6 8.9 4.7e-54 184.0 8.9 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Synaptobrevin PF00957.21 KXG51195.1 - 0.029 14.2 0.5 0.061 13.1 0.5 1.5 1 0 0 1 1 1 0 Synaptobrevin Gram_pos_anchor PF00746.21 KXG51195.1 - 1.7 8.7 3.0 1.7 8.7 0.1 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif CPBP PF02517.16 KXG51196.1 - 2.6e-16 59.8 6.4 2.6e-16 59.8 6.4 2.5 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease COesterase PF00135.28 KXG51197.1 - 3.3e-84 283.6 0.0 4.6e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG51197.1 - 1.7e-06 28.0 0.1 8.9e-06 25.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3328 PF11807.8 KXG51198.1 - 1.3e-25 90.5 4.7 2.4e-25 89.6 4.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) OPT PF03169.15 KXG51199.1 - 7.3e-122 408.1 39.8 8.3e-122 407.9 39.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GST_N_2 PF13409.6 KXG51200.1 - 1.2e-10 41.6 0.0 3.5e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXG51200.1 - 7.3e-10 38.9 0.0 1.3e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXG51200.1 - 2.7e-09 37.2 0.0 5.1e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXG51200.1 - 5.3e-08 32.8 0.0 9.1e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXG51200.1 - 1.1e-07 32.1 0.0 2.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXG51200.1 - 1.4e-07 31.6 0.0 2.5e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cu_amine_oxid PF01179.20 KXG51201.1 - 3.6e-109 365.4 0.8 5.7e-78 262.6 0.1 2.1 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KXG51201.1 - 0.0004 20.7 0.0 0.00099 19.5 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Sugar_tr PF00083.24 KXG51203.1 - 9.3e-77 258.8 27.2 1.1e-76 258.6 27.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG51203.1 - 1.9e-19 69.9 39.4 3.9e-18 65.5 34.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG51203.1 - 0.00099 18.1 3.3 0.00099 18.1 3.3 2.4 2 0 0 2 2 2 1 MFS_1 like family DUF3270 PF11674.8 KXG51203.1 - 1.1 9.5 3.4 6.1 7.1 0.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) Phage_holin_2_4 PF16082.5 KXG51203.1 - 2.2 8.1 5.4 0.41 10.4 0.3 2.4 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Peptidase_A24 PF01478.18 KXG51205.1 - 0.22 11.9 7.9 0.72 10.3 0.8 3.0 3 0 0 3 3 3 0 Type IV leader peptidase family CorA PF01544.18 KXG51206.1 - 5.8e-15 55.4 4.8 4.4e-14 52.5 3.3 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Tim17 PF02466.19 KXG51208.1 - 2.7e-31 108.2 7.8 3.4e-31 107.9 7.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.6 KXG51208.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal NmrA PF05368.13 KXG51209.1 - 7.3e-20 71.5 0.0 8.8e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KXG51209.1 - 3e-06 27.5 0.0 3.5e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 KXG51209.1 - 0.0015 18.1 0.0 0.0081 15.7 0.0 2.0 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus NAD_binding_10 PF13460.6 KXG51209.1 - 0.028 14.3 0.0 0.12 12.2 0.0 2.2 2 2 0 2 2 2 0 NAD(P)H-binding Shikimate_DH PF01488.20 KXG51209.1 - 0.062 13.4 0.1 0.94 9.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KXG51209.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.6 1 1 0 1 1 1 0 TrkA-N domain Fructosamin_kin PF03881.14 KXG51210.1 - 2.6e-31 108.9 0.0 3.5e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KXG51210.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family EcKinase PF02958.20 KXG51210.1 - 0.07 12.4 0.0 0.095 12.0 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase ANAPC4_WD40 PF12894.7 KXG51211.1 - 1.2e-06 28.7 0.1 8.4 6.8 0.0 6.0 4 3 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXG51211.1 - 1.4e-05 25.7 1.4 19 6.3 0.0 7.2 6 1 0 6 6 6 1 WD domain, G-beta repeat NACHT PF05729.12 KXG51211.1 - 0.0043 17.0 0.1 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KXG51211.1 - 0.0082 16.5 0.0 0.025 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Abhydrolase_6 PF12697.7 KXG51211.1 - 0.011 16.3 0.0 0.12 13.0 0.0 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family MFS_1 PF07690.16 KXG51212.1 - 6.4e-26 91.1 53.9 3.9e-19 68.8 29.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG51212.1 - 0.00063 18.7 11.2 0.00063 18.7 11.2 1.9 1 1 1 2 2 2 1 MFS_1 like family Fungal_trans PF04082.18 KXG51213.1 - 9.9e-13 47.7 0.0 1.7e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KXG51214.1 - 6.8e-23 81.1 0.0 5.6e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXG51214.1 - 4.4e-11 42.8 0.0 2.6e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG51214.1 - 2.5e-08 34.1 0.0 4.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXG51214.1 - 4.4e-05 23.1 0.0 5.8e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXG51214.1 - 0.019 14.1 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 KXG51215.1 - 1.2e-09 38.3 0.1 2e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG51215.1 - 3.3e-08 33.4 0.1 1.8e-07 31.0 0.2 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXG51215.1 - 0.064 14.3 0.0 0.12 13.4 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase F-box-like PF12937.7 KXG51217.1 - 0.00066 19.5 0.4 0.0013 18.6 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KXG51217.1 - 0.046 13.6 0.1 0.046 13.6 0.1 1.8 2 0 0 2 2 2 0 F-box F-box PF00646.33 KXG51217.1 - 0.15 12.0 0.3 0.36 10.8 0.3 1.6 1 0 0 1 1 1 0 F-box domain Aldedh PF00171.22 KXG51218.1 - 2.1e-130 435.3 0.0 2.4e-130 435.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TRAPPC9-Trs120 PF08626.11 KXG51219.1 - 0 1507.9 0.0 0 1507.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 KXG51219.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3684 PF12449.8 KXG51220.1 - 0 1404.0 0.0 0 1403.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KXG51220.1 - 0.00023 21.0 0.0 0.00053 19.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GP11 PF08677.10 KXG51220.1 - 0.086 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 GP11 baseplate wedge protein WLM PF08325.10 KXG51220.1 - 2.4 8.2 6.4 0.5 10.4 0.5 2.2 2 0 0 2 2 2 0 WLM domain Chorismate_bind PF00425.18 KXG51221.1 - 7e-64 215.9 0.0 1.1e-61 208.7 0.0 2.6 2 1 0 2 2 2 1 chorismate binding enzyme GATase PF00117.28 KXG51221.1 - 1.6e-30 106.3 0.0 2.6e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KXG51221.1 - 4.8e-10 39.8 0.0 1.4e-09 38.3 0.0 1.8 1 1 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KXG51221.1 - 0.0021 17.9 0.6 0.011 15.5 0.6 2.0 1 1 0 1 1 1 1 Peptidase C26 Med6 PF04934.14 KXG51222.1 - 3.6e-38 130.4 0.0 4.8e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component DUF2890 PF11081.8 KXG51222.1 - 0.15 12.1 12.3 0.038 14.1 3.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Ank_5 PF13857.6 KXG51223.1 - 0.00023 21.4 0.1 0.42 11.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXG51223.1 - 0.00078 20.0 0.0 0.0072 16.9 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXG51223.1 - 0.024 15.1 0.3 5.9 7.5 0.2 3.5 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 KXG51223.1 - 0.029 15.0 0.1 0.16 12.6 0.1 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG51223.1 - 0.078 13.6 0.0 16 6.4 0.0 3.5 2 0 0 2 2 2 0 Ankyrin repeat Lysine_decarbox PF03641.14 KXG51224.1 - 3.5e-28 98.3 0.0 5.3e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase Proteasome PF00227.26 KXG51225.1 - 2.7e-49 167.2 0.0 3.4e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXG51225.1 - 1.3e-12 47.2 0.4 2e-12 46.6 0.4 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.14 KXG51226.1 - 2.6e-45 153.1 6.4 2.9e-45 153.0 6.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4231 PF14015.6 KXG51226.1 - 0.25 11.8 1.1 6.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF4349 PF14257.6 KXG51226.1 - 0.35 10.3 0.0 0.35 10.3 0.0 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) Sld7_C PF18596.1 KXG51227.1 - 2.8e-15 56.2 0.0 5.5e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Sld7 C-terminal domain UPF0220 PF05255.11 KXG51228.1 - 2.5e-71 238.6 2.6 2.8e-71 238.4 2.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF998 PF06197.13 KXG51228.1 - 9.5e-06 25.3 5.9 1.1e-05 25.1 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF998) ATP1G1_PLM_MAT8 PF02038.16 KXG51228.1 - 0.02 14.3 1.0 0.041 13.3 0.1 2.0 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Fes1 PF08609.10 KXG51229.1 - 1.3e-30 106.1 1.4 2.9e-30 105.0 0.8 1.8 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_EZ PF13513.6 KXG51229.1 - 1.1e-07 32.2 0.1 6.2e-05 23.4 0.0 2.9 3 1 1 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 KXG51229.1 - 2.6e-06 27.7 0.1 6.6e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 HEAT repeats Arm PF00514.23 KXG51229.1 - 3.7e-05 23.6 0.0 0.0022 18.0 0.0 2.5 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KXG51229.1 - 0.00023 21.2 0.0 0.026 14.7 0.0 2.7 2 0 0 2 2 2 1 HEAT repeat Adaptin_N PF01602.20 KXG51229.1 - 0.012 14.3 0.0 0.018 13.6 0.0 1.2 1 0 0 1 1 1 0 Adaptin N terminal region V-ATPase_H_C PF11698.8 KXG51229.1 - 0.017 15.3 0.1 0.35 11.0 0.0 2.1 1 1 1 2 2 2 0 V-ATPase subunit H Atx10homo_assoc PF09759.9 KXG51229.1 - 0.035 14.1 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Actin PF00022.19 KXG51230.1 - 3.9e-150 500.0 0.0 1.5e-149 498.0 0.0 1.7 1 1 0 1 1 1 1 Actin GARS_A PF01071.19 KXG51231.1 - 2.1e-81 272.3 0.0 3.2e-81 271.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 KXG51231.1 - 5.4e-34 117.6 0.0 9.9e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 KXG51231.1 - 8.6e-34 116.2 0.0 2.8e-33 114.6 0.0 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KXG51231.1 - 2e-26 92.1 0.2 5e-26 90.8 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KXG51231.1 - 7.4e-15 55.4 1.5 3.2e-14 53.3 1.5 2.1 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_2 PF08442.10 KXG51231.1 - 0.00033 20.3 0.0 0.0016 18.0 0.0 2.0 3 0 0 3 3 3 1 ATP-grasp domain ATP-grasp PF02222.22 KXG51231.1 - 0.00056 19.5 0.0 0.00098 18.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KXG51231.1 - 0.0011 19.0 0.1 0.004 17.2 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KXG51231.1 - 0.0016 18.0 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 KXG51231.1 - 0.016 14.8 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 KXG51231.1 - 0.036 13.3 0.0 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Pet127 PF08634.10 KXG51232.1 - 1.1e-115 385.9 0.2 1.6e-115 385.3 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Peptidase_S49 PF01343.18 KXG51232.1 - 0.1 12.5 0.5 0.21 11.5 0.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 PGA2 PF07543.12 KXG51232.1 - 3.5 7.6 9.7 16 5.5 9.7 2.2 1 0 0 1 1 1 0 Protein trafficking PGA2 LRR_6 PF13516.6 KXG51233.1 - 0.013 15.5 0.6 2e+02 2.4 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich repeat SOAR PF16533.5 KXG51233.1 - 0.045 13.7 0.0 0.18 11.8 0.0 2.0 1 0 0 1 1 1 0 STIM1 Orai1-activating region T4_Rnl2_C PF18043.1 KXG51233.1 - 0.046 13.9 0.0 0.097 12.8 0.0 1.5 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal IGPD PF00475.18 KXG51235.1 - 3.4e-56 189.5 0.6 4.6e-56 189.1 0.6 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Arena_RNA_pol PF06317.11 KXG51235.1 - 0.28 8.3 0.0 0.37 7.9 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase Catalase-rel PF06628.12 KXG51236.1 - 0.023 14.9 0.1 0.042 14.1 0.1 1.4 1 0 0 1 1 1 0 Catalase-related immune-responsive Gly_transf_sug PF04488.15 KXG51237.1 - 1.1e-19 70.9 0.0 2e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DER1 PF04511.15 KXG51238.1 - 3.5e-49 167.3 5.9 4.1e-49 167.1 5.9 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 KXG51238.1 - 0.2 11.6 5.6 0.31 11.0 5.6 1.3 1 0 0 1 1 1 0 Rhomboid family Histone PF00125.24 KXG51239.1 - 1.4e-41 141.9 0.4 2.4e-41 141.1 0.4 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXG51239.1 - 0.0002 21.5 0.0 0.00041 20.5 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXG51239.1 - 0.003 17.9 0.1 0.0056 17.0 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KXG51239.1 - 0.02 15.2 0.5 0.05 13.9 0.5 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cohesin_load PF10345.9 KXG51240.1 - 4.3e-177 590.2 5.2 5.1e-177 590.0 5.2 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 KXG51240.1 - 0.11 12.8 0.1 0.11 12.8 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Pox_Ag35 PF03286.14 KXG51240.1 - 0.27 11.0 0.9 0.77 9.5 0.9 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Abhydrolase_1 PF00561.20 KXG51241.1 - 2.5e-11 43.7 0.1 8.8e-11 41.9 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG51241.1 - 3.1e-08 33.2 0.0 1.5e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Bunya_G1 PF03557.15 KXG51241.1 - 0.25 9.3 0.1 0.73 7.7 0.0 1.6 2 0 0 2 2 2 0 Bunyavirus glycoprotein G1 Complex1_LYR_2 PF13233.6 KXG51243.1 - 4.1e-06 27.5 0.2 5.7e-06 27.0 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KXG51243.1 - 1.1e-05 25.4 0.1 2e-05 24.5 0.1 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) RNA_pol_L_2 PF13656.6 KXG51244.1 - 2e-32 110.7 0.0 2.6e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KXG51244.1 - 3.5e-14 52.0 0.0 4.8e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Miff PF05644.11 KXG51245.1 - 0.12 12.0 2.2 0.17 11.5 2.2 1.3 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff RRP36 PF06102.12 KXG51246.1 - 2e-46 158.0 25.1 2e-46 158.0 25.1 2.1 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 ALMT PF11744.8 KXG51246.1 - 0.24 10.2 19.5 0.02 13.7 8.1 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter NIF PF03031.18 KXG51247.1 - 5e-25 88.1 0.0 4.3e-24 85.0 0.0 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase NST1 PF13945.6 KXG51247.1 - 6.8 6.8 9.0 22 5.1 9.0 1.8 1 0 0 1 1 1 0 Salt tolerance down-regulator Ring_hydroxyl_A PF00848.19 KXG51248.1 - 1.1e-11 45.1 0.1 1.4e-11 44.7 0.1 1.2 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) DAO PF01266.24 KXG51249.1 - 2.5e-37 129.3 0.0 2.8e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXG51249.1 - 0.1 11.6 0.2 0.28 10.2 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Condensation PF00668.20 KXG51251.1 - 1e-65 222.3 0.0 1.3e-65 221.9 0.0 1.0 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KXG51251.1 - 7.9e-14 51.8 0.0 1.5e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.28 KXG51253.1 - 2.9e-53 181.0 0.0 3.4e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme FAD_binding_8 PF08022.12 KXG51254.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain AMP-binding PF00501.28 KXG51255.1 - 3.7e-53 180.7 0.0 4.5e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme WD40 PF00400.32 KXG51256.1 - 9.1e-138 444.1 47.5 3.6e-12 46.6 0.2 13.6 13 0 0 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG51256.1 - 1.9e-60 201.2 0.0 3.6e-06 27.2 0.0 14.0 3 1 12 15 15 14 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXG51256.1 - 2.1e-20 73.0 0.6 0.027 13.5 0.0 10.8 3 2 8 11 11 11 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KXG51256.1 - 3.6e-17 61.7 9.1 3.4 7.4 0.0 11.3 11 0 0 11 11 11 5 Proteasome subunit A N-terminal signature NACHT PF05729.12 KXG51256.1 - 5.1e-11 42.8 0.1 1.4e-10 41.3 0.1 1.7 1 0 0 1 1 1 1 NACHT domain PQQ_2 PF13360.6 KXG51256.1 - 6.8e-11 42.2 14.6 0.0086 15.7 0.7 5.8 2 1 3 6 6 6 5 PQQ-like domain WD40_like PF17005.5 KXG51256.1 - 1.6e-10 40.8 0.0 0.039 13.3 0.0 6.4 4 2 4 8 8 8 1 WD40-like domain PD40 PF07676.12 KXG51256.1 - 5.1e-10 39.0 14.2 18 5.4 0.0 11.6 13 0 0 13 13 12 0 WD40-like Beta Propeller Repeat Helo_like_N PF17111.5 KXG51256.1 - 5.3e-10 39.0 0.2 1.2e-09 37.8 0.2 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Frtz PF11768.8 KXG51256.1 - 3.1e-09 35.7 0.0 0.016 13.6 0.0 5.9 3 1 5 8 8 8 2 WD repeat-containing and planar cell polarity effector protein Fritz Big_7 PF17957.1 KXG51256.1 - 6.4e-08 33.3 0.2 8.4 7.2 0.0 7.6 5 4 4 9 9 7 0 Bacterial Ig domain Cytochrom_D1 PF02239.16 KXG51256.1 - 1e-05 24.2 0.0 2.6 6.5 0.0 4.9 1 1 2 5 5 5 1 Cytochrome D1 heme domain AAA_16 PF13191.6 KXG51256.1 - 2e-05 25.0 0.4 6.9e-05 23.3 0.1 2.0 2 0 0 2 2 1 1 AAA ATPase domain TruB_C PF09142.11 KXG51256.1 - 6.2e-05 22.7 2.3 1.2e+02 2.6 0.0 8.0 10 0 0 10 10 9 0 tRNA Pseudouridine synthase II, C terminal Coatomer_WDAD PF04053.14 KXG51256.1 - 6.7e-05 22.1 0.0 2.4 7.1 0.0 4.5 2 1 4 6 6 6 2 Coatomer WD associated region RAB3GAP2_N PF14655.6 KXG51256.1 - 7.2e-05 22.2 0.7 0.49 9.6 0.0 5.7 6 2 1 7 7 7 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 KXG51256.1 - 7.6e-05 21.6 0.4 0.54 8.8 0.0 4.8 5 0 0 5 5 5 1 Nucleoporin Nup120/160 Nbas_N PF15492.6 KXG51256.1 - 0.00022 20.7 10.7 0.36 10.1 0.0 7.4 3 3 2 7 7 7 1 Neuroblastoma-amplified sequence, N terminal PSII_BNR PF14870.6 KXG51256.1 - 0.0022 17.3 0.3 7.3 5.7 0.0 4.0 2 1 1 4 4 4 0 Photosynthesis system II assembly factor YCF48 DUF484 PF04340.12 KXG51256.1 - 0.0036 17.0 0.9 0.3 10.7 0.5 3.1 3 0 0 3 3 3 1 Protein of unknown function, DUF484 AAA_22 PF13401.6 KXG51256.1 - 0.013 15.8 0.0 0.033 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXG51256.1 - 0.028 14.9 0.0 0.076 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KXG51256.1 - 0.029 14.3 0.1 0.05 13.5 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 KXG51256.1 - 0.05 12.8 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain SesA PF17107.5 KXG51256.1 - 0.064 13.5 1.4 0.13 12.4 1.4 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3829 PF12889.7 KXG51256.1 - 0.079 12.4 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Thymidylate_kin PF02223.17 KXG51256.1 - 0.11 12.1 1.0 0.14 11.9 0.1 1.6 2 0 0 2 2 1 0 Thymidylate kinase AAA_13 PF13166.6 KXG51256.1 - 0.37 9.4 0.7 4.9 5.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Retro_M PF02813.14 KXG51256.1 - 1 9.8 11.4 27 5.3 0.0 6.8 3 2 4 7 7 7 0 Retroviral M domain Bacillus_HBL PF05791.11 KXG51256.1 - 1.7 8.4 4.2 1.6 8.5 1.7 2.0 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Hydrolase_4 PF12146.8 KXG51257.1 - 9.4e-06 25.1 0.0 0.0045 16.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXG51257.1 - 0.00091 18.8 0.0 0.11 11.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family LIP PF03583.14 KXG51257.1 - 0.0038 16.6 0.2 0.57 9.5 0.2 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_6 PF12697.7 KXG51257.1 - 0.0047 17.6 0.1 0.007 17.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KXG51257.1 - 0.02 13.8 0.0 0.052 12.5 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S15 PF02129.18 KXG51257.1 - 0.028 14.0 0.1 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) ArgJ PF01960.18 KXG51258.1 - 1.4e-120 402.5 0.4 1.8e-120 402.1 0.4 1.1 1 0 0 1 1 1 1 ArgJ family Acetyltransf_10 PF13673.7 KXG51259.1 - 2.6e-08 33.8 0.0 3.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXG51259.1 - 1.7e-05 25.2 0.0 2.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG51259.1 - 2.8e-05 24.4 0.0 4.4e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family AA_permease_2 PF13520.6 KXG51260.1 - 6.2e-64 216.4 44.3 7.8e-64 216.1 44.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG51260.1 - 8.6e-17 60.9 34.8 1.2e-16 60.4 34.8 1.1 1 0 0 1 1 1 1 Amino acid permease TctB PF07331.11 KXG51261.1 - 2.2 8.5 21.3 0.059 13.6 11.1 2.4 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF3176 PF11374.8 KXG51262.1 - 7.9e-37 125.7 0.5 2e-36 124.4 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) stn_TNFRSF12A PF12191.8 KXG51262.1 - 0.026 14.8 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain TPR_12 PF13424.6 KXG51263.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat CAP59_mtransfer PF11735.8 KXG51265.1 - 6.3e-72 242.1 0.0 9e-72 241.6 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Gly_transf_sug PF04488.15 KXG51265.1 - 2.4e-06 28.1 0.0 5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif PIG-L PF02585.17 KXG51266.1 - 9.7e-23 81.2 0.0 1.4e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Gly_transf_sug PF04488.15 KXG51267.1 - 7.6e-11 42.5 0.0 1.7e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Nuc_sug_transp PF04142.15 KXG51268.1 - 9e-32 110.5 14.9 1.2e-31 110.1 14.9 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KXG51268.1 - 2.6e-06 26.9 5.9 2.6e-06 26.9 5.9 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXG51268.1 - 2e-05 24.8 24.6 0.0027 17.9 12.0 2.5 3 0 0 3 3 3 2 EamA-like transporter family TMEM234 PF10639.9 KXG51268.1 - 0.028 14.4 0.9 0.028 14.4 0.9 2.4 2 1 0 2 2 2 0 Putative transmembrane family 234 HAUS4 PF14735.6 KXG51268.1 - 0.2 11.3 0.1 0.32 10.6 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Aminotran_1_2 PF00155.21 KXG51269.1 - 3e-51 174.7 0.0 3.5e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II NifU PF01106.17 KXG51269.1 - 0.055 13.6 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 NifU-like domain DDRGK PF09756.9 KXG51269.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 DDRGK domain ECH_1 PF00378.20 KXG51269.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase MFS_1 PF07690.16 KXG51270.1 - 2.2e-39 135.4 29.9 2.2e-39 135.4 29.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG51270.1 - 3.8e-11 42.5 26.0 6.1e-11 41.8 26.1 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter FeoB_Cyto PF17910.1 KXG51272.1 - 0.14 12.7 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 FeoB cytosolic helical domain MreB_Mbl PF06723.13 KXG51273.1 - 0.0066 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein AAA_16 PF13191.6 KXG51274.1 - 6.6e-07 29.9 0.3 7.9e-06 26.4 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain TPR_12 PF13424.6 KXG51274.1 - 4.1e-06 27.0 26.2 1.5 9.1 0.5 9.9 9 1 0 9 9 9 3 Tetratricopeptide repeat NACHT PF05729.12 KXG51274.1 - 3.9e-05 23.6 0.7 0.00093 19.2 0.2 3.1 2 1 0 2 2 2 1 NACHT domain TPR_7 PF13176.6 KXG51274.1 - 0.00019 21.2 3.9 6 7.1 0.2 6.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXG51274.1 - 0.00019 21.2 19.2 18 5.4 0.0 9.2 10 0 0 10 10 10 0 Tetratricopeptide repeat AAA_22 PF13401.6 KXG51274.1 - 0.00019 21.7 0.7 0.004 17.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain TPR_14 PF13428.6 KXG51274.1 - 0.0015 19.2 17.7 23 6.1 0.0 10.0 10 0 0 10 10 9 0 Tetratricopeptide repeat AAA_30 PF13604.6 KXG51274.1 - 0.008 15.9 0.0 0.026 14.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_19 PF14559.6 KXG51274.1 - 0.0099 16.4 9.3 19 5.9 0.2 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat DRY_EERY PF09750.9 KXG51274.1 - 0.035 14.4 0.3 0.14 12.4 0.3 2.0 1 0 0 1 1 1 0 Alternative splicing regulator TPR_2 PF07719.17 KXG51274.1 - 2 8.7 17.5 2.1 8.6 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Fungal_trans_2 PF11951.8 KXG51275.1 - 4.1e-07 29.1 0.6 6.2e-07 28.6 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KXG51276.1 - 6.4e-11 41.8 0.0 1.2e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KXG51277.1 - 5.7e-18 65.3 0.0 2.8e-09 36.7 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 KXG51277.1 - 0.00086 18.4 0.0 0.0041 16.2 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 KXG51277.1 - 0.0014 18.8 0.0 0.0035 17.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXG51277.1 - 0.0019 17.5 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXG51277.1 - 0.036 14.3 0.0 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain AAA_27 PF13514.6 KXG51277.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DAO PF01266.24 KXG51277.1 - 0.11 12.1 0.0 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Cellulase PF00150.18 KXG51278.1 - 7.5e-17 61.7 5.3 1e-16 61.2 5.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KXG51278.1 - 2e-11 43.6 10.2 7.3e-11 41.8 10.2 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF4038 PF13204.6 KXG51278.1 - 2.1e-06 27.6 1.6 3e-06 27.1 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_2_C PF02836.17 KXG51278.1 - 4.1e-05 22.8 0.2 9.8e-05 21.6 0.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KXG51278.1 - 0.002 17.6 0.3 0.004 16.6 0.3 1.5 1 0 0 1 1 1 1 Beta-galactosidase NAD_binding_4 PF07993.12 KXG51279.1 - 7.1e-21 74.5 0.2 2.3e-11 43.3 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein PP-binding PF00550.25 KXG51279.1 - 9.7e-05 22.7 0.0 0.00022 21.5 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Orbi_VP4 PF05059.12 KXG51279.1 - 0.19 9.7 0.0 0.27 9.2 0.0 1.2 1 0 0 1 1 1 0 Orbivirus VP4 core protein Aconitase PF00330.20 KXG51280.1 - 4.4e-67 227.1 0.0 1.6e-65 222.0 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXG51280.1 - 9e-16 58.4 0.0 1.8e-14 54.2 0.0 2.3 1 1 0 1 1 1 1 Aconitase C-terminal domain Iso_dh PF00180.20 KXG51280.1 - 3.7e-10 39.5 0.0 6.1e-08 32.2 0.0 2.2 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HMGL-like PF00682.19 KXG51281.1 - 1.2e-71 241.4 0.0 2.2e-71 240.5 0.0 1.4 1 0 0 1 1 1 1 HMGL-like She2p PF11435.8 KXG51281.1 - 0.17 11.5 0.1 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 RNA binding protein She2p DIOX_N PF14226.6 KXG51282.1 - 2.4e-22 79.9 0.1 3.9e-22 79.2 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG51282.1 - 1e-09 38.8 0.0 1.8e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aminotran_4 PF01063.19 KXG51283.1 - 4.2e-34 118.3 0.0 5.2e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV MFS_1 PF07690.16 KXG51284.1 - 5.7e-19 68.2 63.6 1.2e-14 54.0 36.7 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily Phage_holin_5_1 PF06946.11 KXG51284.1 - 6.5 7.2 7.8 3.4 8.1 0.5 3.0 2 1 1 3 3 3 0 Bacteriophage A118-like holin, Hol118 G0-G1_switch_2 PF15103.6 KXG51286.1 - 0.024 15.1 0.5 0.07 13.6 0.0 2.0 2 1 1 3 3 3 0 G0/G1 switch protein 2 XkdW PF09636.10 KXG51286.1 - 0.12 12.4 0.1 0.38 10.9 0.0 1.8 2 0 0 2 2 2 0 XkdW protein Amino_oxidase PF01593.24 KXG51287.1 - 2.7e-10 40.1 0.0 2.9e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DUF3055 PF11256.8 KXG51287.1 - 0.22 11.8 0.0 0.33 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3055) Amino_oxidase PF01593.24 KXG51288.1 - 5.3e-17 62.2 0.0 5.6e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXG51288.1 - 6.4e-13 48.7 0.2 9e-13 48.3 0.2 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXG51288.1 - 8.3e-09 35.5 0.0 9e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXG51288.1 - 7.8e-08 32.1 0.5 1.5e-07 31.1 0.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG51288.1 - 1.7e-07 30.8 0.1 1.8e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG51288.1 - 1.9e-06 27.2 1.5 2.3e-06 26.9 1.0 1.4 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXG51288.1 - 1.9e-06 26.8 0.2 2.4e-06 26.5 0.2 1.1 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KXG51288.1 - 1.4e-05 24.4 0.1 1.7e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KXG51288.1 - 2.5e-05 24.8 0.4 4.1e-05 24.0 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG51288.1 - 3.7e-05 23.1 0.1 5e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KXG51288.1 - 4.4e-05 22.9 0.1 5.9e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KXG51288.1 - 0.00012 21.3 0.1 0.00014 21.1 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.18 KXG51288.1 - 0.013 15.4 0.4 0.017 15.0 0.4 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXG51288.1 - 0.023 14.0 0.1 0.026 13.8 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 KXG51288.1 - 0.035 12.6 0.0 0.044 12.2 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 KXG51288.1 - 0.059 13.4 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 KXG51288.1 - 0.066 12.4 0.3 0.098 11.9 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG51288.1 - 0.11 12.4 0.2 0.26 11.2 0.1 1.6 1 1 1 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXG51288.1 - 0.2 10.5 1.2 0.31 9.8 0.4 1.6 1 1 1 2 2 2 0 Tryptophan halogenase GDI PF00996.18 KXG51288.1 - 0.21 10.1 0.1 0.26 9.8 0.1 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor ApbA PF02558.16 KXG51288.1 - 0.23 11.1 0.3 0.37 10.4 0.3 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CMAS PF02353.20 KXG51289.1 - 3.5e-59 200.4 1.1 4.3e-59 200.1 1.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KXG51289.1 - 1.9e-10 41.2 0.0 3.5e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG51289.1 - 4.3e-09 37.0 0.0 7.9e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG51289.1 - 4.9e-09 36.2 0.0 8.1e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG51289.1 - 6.4e-05 23.6 0.0 0.00013 22.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXG51289.1 - 0.0034 17.0 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 KXG51289.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KXG51289.1 - 0.017 14.9 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXG51289.1 - 0.019 14.8 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KXG51289.1 - 0.036 14.1 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3435 PF11917.8 KXG51290.1 - 4.1e-24 85.3 4.2 5.7e-24 84.8 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Myb_DNA-bind_6 PF13921.6 KXG51290.1 - 0.0011 19.2 0.1 0.0029 17.8 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain TPD52 PF04201.15 KXG51290.1 - 0.061 12.9 0.3 0.14 11.7 0.1 1.7 2 0 0 2 2 2 0 Tumour protein D52 family Pkinase PF00069.25 KXG51291.1 - 1e-32 113.5 0.0 1.1e-15 57.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG51291.1 - 1.4e-09 37.6 0.0 0.00019 20.8 0.0 2.9 3 1 0 3 3 3 2 Protein tyrosine kinase DUF2570 PF10828.8 KXG51292.1 - 0.41 10.5 4.5 0.89 9.4 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Pkinase PF00069.25 KXG51293.1 - 7.7e-20 71.4 0.0 1.1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG51293.1 - 7.5e-18 64.7 0.0 1.1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXG51293.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXG51293.1 - 0.082 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KXG51293.1 - 0.18 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF2841 PF11001.8 KXG51295.1 - 4.6e-27 94.5 0.0 8.9e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF4099 PF13351.6 KXG51295.1 - 0.14 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4099) AAA PF00004.29 KXG51296.1 - 4.8e-18 65.9 0.0 4.4e-17 62.7 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KXG51296.1 - 1.1e-17 64.6 1.8 1.7e-17 64.0 1.8 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.6 KXG51296.1 - 0.00027 21.4 0.0 0.00051 20.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KXG51296.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 KXG51296.1 - 0.019 14.3 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 KaiC DUF815 PF05673.13 KXG51296.1 - 0.021 14.0 0.0 0.046 12.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KXG51296.1 - 0.059 13.8 0.0 0.34 11.3 0.0 2.4 3 0 0 3 3 3 0 RNA helicase AAA_5 PF07728.14 KXG51296.1 - 0.064 13.3 0.0 0.33 11.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KXG51296.1 - 0.14 12.6 0.0 0.53 10.8 0.0 2.1 1 1 0 1 1 1 0 ABC transporter NUDIX PF00293.28 KXG51297.1 - 3.4e-06 27.1 0.0 5.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain fragilysinNterm PF16376.5 KXG51299.1 - 0.09 12.5 1.5 0.14 11.9 1.5 1.3 1 0 0 1 1 1 0 N-terminal domain of fragilysin APH PF01636.23 KXG51300.1 - 6e-14 52.5 0.0 1.1e-12 48.4 0.0 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG51300.1 - 0.013 15.1 1.3 0.073 12.6 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF4441 PF14536.6 KXG51301.1 - 0.052 13.7 2.2 0.12 12.6 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) DUF3435 PF11917.8 KXG51302.1 - 4e-90 302.7 1.4 4.7e-90 302.5 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2_4 PF13894.6 KXG51302.1 - 0.011 16.5 1.3 0.011 16.5 1.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger DUF4248 PF14053.6 KXG51302.1 - 0.16 12.0 0.1 16 5.6 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) zf-C2H2 PF00096.26 KXG51302.1 - 0.78 10.3 11.0 0.27 11.8 1.7 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type NAD_binding_4 PF07993.12 KXG51303.1 - 2.4e-42 144.9 0.0 4.3e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXG51303.1 - 4.9e-36 124.2 0.0 8.2e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KXG51303.1 - 7.9e-12 45.4 0.0 2.2e-11 43.9 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXG51303.1 - 2.6e-10 41.1 0.1 4.2e-09 37.3 0.1 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 KXG51303.1 - 3.9e-09 36.3 0.0 8e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Dynamin_N PF00350.23 KXG51303.1 - 1.2e-07 32.0 0.0 2.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family 3Beta_HSD PF01073.19 KXG51303.1 - 0.0075 15.3 0.0 2.4 7.1 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Dynamin_M PF01031.20 KXG51303.1 - 0.023 13.9 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Dynamin central region GDP_Man_Dehyd PF16363.5 KXG51303.1 - 0.2 11.0 0.4 0.75 9.1 0.4 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase F-box-like PF12937.7 KXG51304.1 - 2.1e-05 24.3 1.0 2.1e-05 24.3 1.0 1.7 2 0 0 2 2 2 1 F-box-like Nop14 PF04147.12 KXG51304.1 - 0.23 9.7 3.9 0.26 9.4 3.9 1.0 1 0 0 1 1 1 0 Nop14-like family Utp14 PF04615.13 KXG51304.1 - 0.78 8.2 4.8 0.98 7.9 4.8 1.1 1 0 0 1 1 1 0 Utp14 protein CDC45 PF02724.14 KXG51304.1 - 6.4 4.9 7.4 7.9 4.6 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Ank_3 PF13606.6 KXG51305.1 - 6.2e-16 56.9 2.4 4.3e-05 23.6 0.0 6.1 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 KXG51305.1 - 1.4e-14 54.2 0.4 7.3e-05 23.2 0.0 4.6 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXG51305.1 - 7.5e-14 52.1 0.0 6.3e-06 26.7 0.0 3.4 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXG51305.1 - 9.4e-14 51.2 0.4 3.4e-05 24.1 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KXG51305.1 - 1e-10 41.6 0.4 0.0034 17.6 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) PPS_PS PF02006.16 KXG51305.1 - 0.049 13.2 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase NAD_binding_6 PF08030.12 KXG51306.1 - 3.7e-05 23.9 0.0 4.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF3723 PF12520.8 KXG51307.1 - 3.4e-73 247.1 0.2 4.8e-73 246.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Cupin_7 PF12973.7 KXG51309.1 - 0.1 12.5 1.6 7.3 6.6 0.0 2.5 2 0 0 2 2 2 0 ChrR Cupin-like domain ABC_tran_CTD PF16326.5 KXG51311.1 - 0.064 13.5 0.6 0.089 13.1 0.6 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF501 PF04417.12 KXG51311.1 - 0.074 12.9 0.1 0.094 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF501) HMMR_N PF15905.5 KXG51311.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal FTA4 PF13093.6 KXG51312.1 - 0.00074 19.5 0.0 0.00074 19.5 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 TMF_DNA_bd PF12329.8 KXG51312.1 - 0.018 15.1 0.1 0.035 14.1 0.0 1.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 KXG51312.1 - 0.066 13.0 0.1 0.097 12.5 0.1 1.2 1 0 0 1 1 1 0 Septum formation initiator NPV_P10 PF05531.12 KXG51312.1 - 0.076 13.5 0.1 0.38 11.3 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Trimer_CC PF08954.11 KXG51312.1 - 0.11 12.1 0.2 0.87 9.2 0.0 2.1 1 1 1 2 2 2 0 Trimerisation motif Lebercilin PF15619.6 KXG51312.1 - 0.12 12.0 0.1 0.17 11.6 0.1 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Patatin PF01734.22 KXG51313.1 - 8.5e-15 55.5 2.8 3.4e-11 43.7 0.0 3.1 2 2 1 3 3 3 2 Patatin-like phospholipase PUB_1 PF18486.1 KXG51313.1 - 0.11 12.3 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain Gag_p19 PF02228.16 KXG51313.1 - 0.16 12.4 0.2 0.39 11.2 0.1 1.7 1 1 0 1 1 1 0 Major core protein p19 ATPase_2 PF01637.18 KXG51313.1 - 0.25 11.2 0.3 1.8 8.4 0.1 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NUDIX PF00293.28 KXG51314.1 - 1.6e-07 31.4 0.2 3.9e-07 30.2 0.2 1.7 1 1 0 1 1 1 1 NUDIX domain EST1_DNA_bind PF10373.9 KXG51315.1 - 0.29 10.6 3.7 0.31 10.5 1.0 2.4 2 1 0 2 2 2 0 Est1 DNA/RNA binding domain HMG_CoA_synt_C PF08540.10 KXG51316.1 - 3.8e-97 325.3 0.8 4.7e-97 325.0 0.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KXG51316.1 - 5.6e-84 280.3 0.0 8.9e-84 279.7 0.0 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Mur_ligase_C PF02875.21 KXG51316.1 - 0.038 14.2 0.0 0.08 13.2 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Catalase-rel PF06628.12 KXG51317.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Catalase-related immune-responsive APH PF01636.23 KXG51319.1 - 1.2e-19 71.2 0.0 1.9e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG51319.1 - 0.00014 21.6 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KXG51319.1 - 0.0023 17.3 0.0 0.83 9.0 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXG51319.1 - 0.044 13.4 0.0 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 RIO1 family DUF3652 PF12372.8 KXG51321.1 - 0.29 11.1 4.7 55 3.8 0.1 4.7 2 1 3 5 5 5 0 Huntingtin protein region DUF2408 PF10303.9 KXG51321.1 - 3.3 8.3 12.2 1.6 9.3 7.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Peptidase_S8 PF00082.22 KXG51322.1 - 5.7e-30 104.6 16.1 1e-29 103.7 16.1 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXG51322.1 - 2.9e-13 50.3 0.0 6.3e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 ADH_zinc_N PF00107.26 KXG51323.1 - 3.9e-16 59.2 0.0 5.8e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXG51323.1 - 6.5e-05 22.4 0.1 9.8e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXG51323.1 - 0.00056 19.3 0.0 0.00082 18.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KXG51323.1 - 0.0086 17.1 0.0 0.013 16.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 KXG51323.1 - 0.069 12.9 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.21 KXG51323.1 - 0.28 10.5 1.3 0.46 9.8 1.3 1.3 1 0 0 1 1 1 0 ThiF family Abhydrolase_6 PF12697.7 KXG51324.1 - 1.1e-12 49.1 0.3 2e-12 48.2 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG51324.1 - 2.2e-08 33.6 0.0 3.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXG51324.1 - 0.00017 21.3 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold RRM_1 PF00076.22 KXG51325.1 - 7.1e-24 83.4 0.0 8.4e-24 83.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXG51325.1 - 0.0036 17.4 0.0 0.0063 16.6 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 KXG51325.1 - 0.024 14.7 0.0 0.029 14.4 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif Limkain-b1 PF11608.8 KXG51325.1 - 0.1 12.7 0.1 0.12 12.5 0.1 1.3 1 1 0 1 1 1 0 Limkain b1 RRM_occluded PF16842.5 KXG51325.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif Helo_like_N PF17111.5 KXG51328.1 - 2.8e-91 304.5 10.0 1.8e-83 279.0 0.9 2.2 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins PRESAN PF09687.10 KXG51328.1 - 0.0052 17.3 2.6 0.018 15.6 0.0 2.6 2 1 0 3 3 3 1 Plasmodium RESA N-terminal DUF1043 PF06295.12 KXG51328.1 - 0.0076 16.3 3.1 0.054 13.5 0.6 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1043) DUF1664 PF07889.12 KXG51328.1 - 0.055 13.5 7.6 0.29 11.2 2.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF5320 PF17253.2 KXG51328.1 - 0.075 14.1 0.2 7.3 7.7 0.0 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5320) GTP-bdg_M PF16360.5 KXG51328.1 - 0.24 12.0 2.1 22 5.7 0.1 3.6 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region Syntaxin-6_N PF09177.11 KXG51328.1 - 0.46 11.1 12.9 3.1 8.4 2.5 3.0 2 1 0 3 3 3 0 Syntaxin 6, N-terminal LMBR1 PF04791.16 KXG51328.1 - 0.71 8.7 2.0 0.85 8.4 2.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF16 PF01519.16 KXG51328.1 - 1.1 9.8 7.6 8.1 7.0 0.4 3.0 2 1 0 3 3 2 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 KXG51328.1 - 1.3 9.6 5.6 11 6.6 0.0 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein HMMR_N PF15905.5 KXG51328.1 - 3.4 7.0 16.9 2.6 7.5 3.0 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal LOH1CR12 PF10158.9 KXG51328.1 - 4.3 7.4 6.6 4.9 7.2 0.8 3.3 1 1 3 4 4 4 0 Tumour suppressor protein AATF-Che1 PF13339.6 KXG51328.1 - 5 7.8 11.9 14 6.3 5.2 3.2 1 1 2 3 3 3 0 Apoptosis antagonizing transcription factor CLZ PF16526.5 KXG51328.1 - 8.4 6.8 9.2 3.3 8.1 0.6 3.6 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HAD_2 PF13419.6 KXG51329.1 - 1.7e-08 34.8 0.0 4.2e-08 33.5 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXG51329.1 - 5.9e-05 23.1 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KXG51329.1 - 0.0005 20.4 0.0 0.0014 19.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3293 PF11697.8 KXG51329.1 - 0.11 13.0 0.2 0.61 10.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3293) Glyco_hydro_3_C PF01915.22 KXG51330.1 - 2.2e-52 178.0 0.1 3.4e-52 177.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXG51330.1 - 8.3e-34 117.4 0.0 2.3e-33 115.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXG51330.1 - 4.8e-26 90.7 0.1 9.1e-26 89.8 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Herpes_UL37_1 PF03970.13 KXG51330.1 - 0.053 12.7 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL37 tegument protein DUF3632 PF12311.8 KXG51331.1 - 6.4e-37 127.7 1.0 8.5e-37 127.3 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Sugar_tr PF00083.24 KXG51332.1 - 6.2e-85 285.7 21.4 7e-85 285.6 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG51332.1 - 5.9e-17 61.6 12.5 5.9e-17 61.6 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane_4 PF12730.7 KXG51332.1 - 0.29 11.1 0.1 0.29 11.1 0.1 4.1 2 2 3 5 5 5 0 ABC-2 family transporter protein Ank_2 PF12796.7 KXG51333.1 - 5.8e-70 231.9 0.0 5.2e-15 55.8 0.0 6.9 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG51333.1 - 1.2e-53 172.7 0.0 0.00036 20.8 0.0 13.1 13 0 0 13 13 13 11 Ankyrin repeat Ank PF00023.30 KXG51333.1 - 4e-47 156.7 0.0 0.002 18.5 0.0 12.2 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.6 KXG51333.1 - 9.6e-44 146.9 0.3 2.6e-07 30.8 0.0 10.6 2 2 9 11 11 11 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXG51333.1 - 3.6e-41 139.0 0.0 7.4e-07 29.6 0.0 8.7 2 1 7 9 9 9 9 Ankyrin repeats (many copies) NACHT_N PF17100.5 KXG51333.1 - 1e-16 61.5 3.6 1.1e-16 61.4 1.8 2.0 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase Cthe_2159 PF14262.6 KXG51333.1 - 0.013 14.9 0.0 5 6.4 0.0 3.7 1 1 2 4 4 4 0 Carbohydrate-binding domain-containing protein Cthe_2159 NACHT PF05729.12 KXG51333.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.14 KXG51333.1 - 0.34 10.1 2.8 1.2 8.4 2.8 1.9 1 1 0 1 1 1 0 KAP family P-loop domain RelA_SpoT PF04607.17 KXG51334.1 - 2.3e-12 47.2 0.5 4.3e-12 46.3 0.1 1.7 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins tRNA-synt_1 PF00133.22 KXG51335.1 - 1.6e-224 746.7 0.1 1.9e-223 743.1 0.1 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXG51335.1 - 3.6e-31 108.2 1.4 3.6e-31 108.2 1.4 2.3 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KXG51335.1 - 1.4e-14 53.6 0.0 4.1e-07 29.1 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KXG51335.1 - 5.7e-07 29.2 4.8 8.9e-05 22.1 0.0 2.8 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KXG51335.1 - 0.051 12.9 0.0 0.51 9.6 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain PepSY PF03413.19 KXG51335.1 - 0.37 11.4 0.0 0.37 11.4 0.0 3.1 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Pkinase PF00069.25 KXG51336.1 - 5e-64 216.2 0.1 5.9e-64 216.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG51336.1 - 5e-18 65.3 0.0 6.8e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXG51336.1 - 3.7e-07 30.3 0.6 0.00011 22.2 0.1 2.6 2 1 0 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXG51336.1 - 0.003 16.4 0.0 0.0057 15.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXG51336.1 - 0.0087 15.4 0.1 0.015 14.7 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXG51336.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 KXG51336.1 - 0.024 14.2 0.6 0.046 13.3 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Aconitase_B_N PF11791.8 KXG51336.1 - 0.064 13.3 0.0 0.54 10.3 0.0 2.1 2 1 0 2 2 2 0 Aconitate B N-terminal domain RNase_P_p30 PF01876.16 KXG51337.1 - 7.5e-67 224.9 0.0 1e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Baculo_gp41 PF04700.12 KXG51338.1 - 0.028 14.2 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region Ureidogly_lyase PF04115.12 KXG51339.1 - 5.9e-64 215.3 0.0 6.9e-64 215.1 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase MutS_V PF00488.21 KXG51340.1 - 7e-73 244.7 0.1 1.3e-72 243.8 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXG51340.1 - 4.6e-44 150.9 3.5 4.6e-44 150.9 3.5 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KXG51340.1 - 5e-20 71.8 0.0 1.2e-19 70.6 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KXG51340.1 - 1e-06 29.1 0.0 2.9e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.6 KXG51340.1 - 0.051 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KXG51340.1 - 0.089 13.3 0.2 0.3 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KXG51340.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sec63 PF02889.16 KXG51341.1 - 3.1e-168 557.4 0.1 3.7e-93 311.4 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KXG51341.1 - 1.8e-49 167.9 0.1 9.5e-28 97.1 0.0 3.9 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KXG51341.1 - 4.1e-29 101.0 0.2 1.5e-28 99.2 0.2 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KXG51341.1 - 2.2e-22 79.9 0.0 1.2e-11 44.9 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXG51341.1 - 3.3e-12 46.7 0.0 8.5e-07 29.3 0.0 3.8 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXG51341.1 - 6.6e-06 26.4 1.2 0.032 14.5 0.1 3.5 3 1 0 3 3 3 2 AAA domain T2SSE PF00437.20 KXG51341.1 - 0.0014 17.7 0.0 1.3 8.0 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 KXG51341.1 - 0.014 14.9 0.0 0.8 9.1 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 KXG51341.1 - 0.15 12.4 0.1 20 5.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain Peptidase_S9 PF00326.21 KXG51342.1 - 2.8e-51 174.0 0.9 4.9e-51 173.2 0.5 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 KXG51342.1 - 0.00039 19.2 0.1 0.012 14.3 0.1 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KXG51342.1 - 0.0011 18.7 0.2 0.0022 17.7 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXG51342.1 - 0.064 12.9 0.5 0.16 11.6 0.5 1.6 1 1 0 1 1 1 0 Putative esterase PD40 PF07676.12 KXG51342.1 - 0.99 9.4 3.5 6.7 6.8 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Glyco_hydro_43 PF04616.14 KXG51344.1 - 7.5e-26 91.1 1.6 1.4e-16 60.7 0.6 2.4 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 MFS_1 PF07690.16 KXG51345.1 - 1e-26 93.8 33.5 1.4e-26 93.3 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG51345.1 - 0.092 11.6 29.1 0.33 9.8 14.4 3.1 2 1 0 3 3 3 0 Sugar (and other) transporter adh_short PF00106.25 KXG51346.1 - 7.8e-08 32.0 0.0 1.4e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG51346.1 - 0.00098 18.7 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG51346.1 - 0.017 15.1 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 KR domain PRA1 PF03208.19 KXG51346.1 - 0.13 11.8 0.2 0.27 10.8 0.1 1.5 2 0 0 2 2 2 0 PRA1 family protein Pkinase PF00069.25 KXG51347.1 - 2.7e-35 122.0 0.0 7.2e-20 71.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG51347.1 - 7.7e-13 48.3 0.0 4.3e-06 26.2 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXG51347.1 - 0.011 15.0 0.0 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KXG51347.1 - 0.039 13.9 0.2 0.077 12.9 0.2 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family CAP_GLY PF01302.25 KXG51348.1 - 8.5e-15 54.5 0.8 1.6e-14 53.6 0.8 1.4 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KXG51348.1 - 4.8e-11 42.2 10.6 4.5e-05 23.2 0.9 2.7 2 0 0 2 2 2 2 CLIP1 zinc knuckle DUF812 PF05667.11 KXG51348.1 - 0.0017 17.3 25.9 0.0048 15.9 13.5 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF812) FAM76 PF16046.5 KXG51348.1 - 0.01 15.2 3.7 0.01 15.2 3.7 3.1 2 1 1 4 4 3 0 FAM76 protein CC2-LZ PF16516.5 KXG51348.1 - 0.013 15.8 27.1 0.031 14.6 0.7 3.5 2 1 1 3 3 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Fez1 PF06818.15 KXG51348.1 - 0.018 15.5 34.2 0.34 11.4 14.3 3.4 2 1 0 3 3 3 0 Fez1 BLOC1_2 PF10046.9 KXG51348.1 - 0.025 14.9 18.8 0.13 12.6 1.8 3.8 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.11 KXG51348.1 - 0.032 14.0 0.6 0.032 14.0 0.6 3.3 2 1 1 3 3 3 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 KXG51348.1 - 0.04 14.4 9.4 0.68 10.4 0.5 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.6 KXG51348.1 - 0.048 12.3 22.2 0.031 12.9 12.2 2.8 1 1 2 3 3 3 0 AAA domain TMF_DNA_bd PF12329.8 KXG51348.1 - 0.052 13.6 29.1 0.55 10.3 2.2 5.0 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding EzrA PF06160.12 KXG51348.1 - 0.092 10.9 25.5 0.1 10.7 9.4 3.1 2 1 0 3 3 3 0 Septation ring formation regulator, EzrA DUF3552 PF12072.8 KXG51348.1 - 0.17 11.2 37.6 0.16 11.4 5.5 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF3552) TPR_MLP1_2 PF07926.12 KXG51348.1 - 0.2 11.7 35.5 0.95 9.5 12.7 3.9 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Cauli_AT PF03233.13 KXG51348.1 - 0.23 11.4 6.6 1.7 8.5 0.5 3.2 3 0 0 3 3 3 0 Aphid transmission protein Lebercilin PF15619.6 KXG51348.1 - 0.26 10.9 30.6 0.24 11.0 2.2 2.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Pox_A_type_inc PF04508.12 KXG51348.1 - 0.36 10.7 19.0 1.2 9.1 2.0 4.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Fib_alpha PF08702.10 KXG51348.1 - 0.59 10.3 13.8 2.5 8.3 0.3 3.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family FliJ PF02050.16 KXG51348.1 - 1 9.6 24.3 2.9 8.1 7.4 3.6 2 1 2 4 4 4 0 Flagellar FliJ protein Spc7 PF08317.11 KXG51348.1 - 1.2 7.9 35.6 2.6 6.9 12.1 3.2 1 1 1 3 3 3 0 Spc7 kinetochore protein AAA_assoc_2 PF16193.5 KXG51348.1 - 1.3 9.5 4.1 0.92 9.9 0.4 2.6 3 0 0 3 3 2 0 AAA C-terminal domain Laminin_II PF06009.12 KXG51348.1 - 1.7 8.6 14.7 7.8 6.5 3.1 3.4 2 1 1 3 3 3 0 Laminin Domain II C1_2 PF03107.16 KXG51348.1 - 1.8 8.9 4.2 20 5.6 0.3 2.4 2 0 0 2 2 2 0 C1 domain APG6_N PF17675.1 KXG51348.1 - 2.3 8.8 38.5 2.1 8.9 4.7 3.5 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF1664 PF07889.12 KXG51348.1 - 3.1 7.8 17.6 1.4 8.9 3.6 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KXG51348.1 - 4.5 6.6 23.2 8.4 5.6 8.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) HemX PF04375.14 KXG51348.1 - 4.6 6.4 23.0 5.8 6.1 5.6 3.2 1 1 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF16 PF01519.16 KXG51348.1 - 4.7 7.8 21.7 7.3 7.1 1.1 4.3 4 1 1 5 5 4 0 Protein of unknown function DUF16 Csm1_N PF18504.1 KXG51348.1 - 4.9 7.6 25.5 3 8.3 0.8 5.9 4 2 3 7 7 6 0 Csm1 N-terminal domain zf_PR_Knuckle PF18445.1 KXG51348.1 - 5.1 7.0 4.8 10 6.0 0.5 2.4 2 0 0 2 2 2 0 PR zinc knuckle motif XhlA PF10779.9 KXG51348.1 - 5.8 7.2 20.1 1.2 9.4 3.1 3.8 3 0 0 3 3 3 0 Haemolysin XhlA Atg14 PF10186.9 KXG51348.1 - 6.4 5.8 29.0 9.5 5.2 11.2 3.4 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 KXG51348.1 - 6.6 7.4 27.8 2 9.1 6.9 4.1 3 1 0 3 3 3 0 SlyX DHR10 PF18595.1 KXG51348.1 - 8.1 6.5 35.2 0.19 11.8 13.7 3.8 2 2 1 3 3 3 0 Designed helical repeat protein 10 domain 3-HAO PF06052.12 KXG51349.1 - 5.7e-56 188.4 0.0 6.7e-56 188.1 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KXG51349.1 - 0.00045 19.9 0.0 0.00089 18.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXG51349.1 - 0.0026 17.4 0.1 0.0039 16.8 0.1 1.2 1 0 0 1 1 1 1 Cupin DZR PF12773.7 KXG51349.1 - 0.029 14.4 1.4 0.069 13.2 1.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon AraC_binding PF02311.19 KXG51349.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain RTC_insert PF05189.13 KXG51350.1 - 1.7e-27 96.0 0.0 2.7e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 KXG51350.1 - 2.1e-26 92.5 0.1 2.5e-26 92.2 0.1 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase SLAC1 PF03595.17 KXG51351.1 - 8e-83 278.4 40.4 9.2e-83 278.2 40.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel HSCB_C PF07743.13 KXG51353.1 - 2.5e-21 75.9 2.2 6.7e-21 74.6 1.0 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KXG51353.1 - 2.9e-06 27.3 0.0 6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 KXG51354.1 - 4.2e-30 103.3 22.1 1.5e-06 28.8 3.0 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.11 KXG51354.1 - 8.9e-15 53.9 6.1 8.9e-15 53.9 6.1 2.0 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 KXG51354.1 - 1.2e-08 35.1 0.0 0.011 16.1 0.1 4.7 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXG51354.1 - 0.025 13.9 0.0 0.061 12.6 0.0 1.6 1 1 0 1 1 1 0 WD40-like domain Nbas_N PF15492.6 KXG51354.1 - 0.056 12.8 0.0 0.37 10.1 0.0 2.1 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal SpoIIE PF07228.12 KXG51355.1 - 1.6e-11 44.5 0.1 7.4e-11 42.3 0.1 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KXG51355.1 - 9.3e-08 32.0 0.2 1.8e-07 31.0 0.2 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KXG51355.1 - 1.2e-07 31.6 0.0 0.0084 15.8 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PWWP PF00855.17 KXG51356.1 - 4.7e-17 62.2 0.0 4.7e-17 62.2 0.0 3.2 3 1 0 3 3 3 1 PWWP domain PAP2_3 PF14378.6 KXG51357.1 - 5e-30 104.6 16.6 3.2e-13 49.8 0.1 3.1 3 0 0 3 3 3 3 PAP2 superfamily PAP2 PF01569.21 KXG51357.1 - 0.0014 18.4 1.2 0.0014 18.4 1.2 2.3 2 1 1 3 3 3 1 PAP2 superfamily PrgI PF12666.7 KXG51357.1 - 0.087 13.5 2.9 0.27 12.0 0.8 2.3 2 0 0 2 2 2 0 PrgI family protein DUF485 PF04341.12 KXG51357.1 - 1.2 9.1 6.3 4.6 7.3 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function, DUF485 PAP2_C PF14360.6 KXG51357.1 - 2.1 8.9 9.1 0.18 12.4 0.7 2.7 2 1 0 2 2 2 0 PAP2 superfamily C-terminal ComA PF02679.15 KXG51358.1 - 2.4e-82 276.1 0.0 2.7e-82 275.9 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) DUF2542 PF10808.8 KXG51358.1 - 0.032 14.7 0.0 0.052 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2542) Fungal_trans PF04082.18 KXG51359.1 - 6.8e-12 45.0 0.0 1.2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG51359.1 - 8.3e-06 25.8 13.0 1.7e-05 24.8 13.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Optomotor-blind PF11078.8 KXG51359.1 - 0.83 10.3 4.4 0.27 11.8 0.9 2.0 2 0 0 2 2 2 0 Optomotor-blind protein N-terminal region SH3_1 PF00018.28 KXG51360.1 - 2.5e-33 113.4 5.9 5.3e-13 48.4 0.1 4.0 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 KXG51360.1 - 2.6e-32 110.5 0.2 4.4e-32 109.7 0.2 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 KXG51360.1 - 2.3e-31 107.4 6.6 2.2e-12 46.6 0.4 3.6 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 KXG51360.1 - 1.4e-19 69.5 0.2 2e-08 33.8 0.0 3.7 4 0 0 4 4 4 3 Variant SH3 domain SAM_4 PF18017.1 KXG51360.1 - 3.4e-05 23.7 0.0 7.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 KXG51360.1 - 5.5e-05 23.1 0.1 0.88 9.7 0.0 3.5 3 0 0 3 3 3 2 SH3 domain DUF1720 PF08226.11 KXG51360.1 - 0.00017 21.9 164.2 0.00059 20.2 38.6 6.7 3 1 2 5 5 5 2 Domain of unknown function (DUF1720) SH3_3 PF08239.11 KXG51360.1 - 0.0053 17.0 5.2 0.13 12.5 0.7 3.2 3 0 0 3 3 3 1 Bacterial SH3 domain SAM_2 PF07647.17 KXG51360.1 - 0.026 14.6 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXG51360.1 - 0.047 14.1 0.0 0.095 13.2 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PRKCSH PF07915.13 KXG51361.1 - 5.3e-19 69.0 0.4 5.3e-19 69.0 0.4 2.7 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KXG51361.1 - 0.0018 18.0 0.3 0.016 14.9 0.3 2.1 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Rota_NSP3 PF01665.16 KXG51361.1 - 0.057 12.5 2.3 0.09 11.9 2.3 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 Pirin PF02678.16 KXG51362.1 - 4.8e-31 106.9 0.1 8.7e-31 106.1 0.1 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KXG51362.1 - 3.6e-24 85.1 0.0 1.5e-23 83.1 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KXG51362.1 - 9.3e-07 28.5 0.8 9.1e-05 22.1 0.8 2.5 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 KXG51362.1 - 0.029 14.0 0.4 0.63 9.8 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF861) LRR_4 PF12799.7 KXG51363.1 - 0.0001 22.6 4.0 8 7.0 0.0 5.7 4 3 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXG51363.1 - 0.0027 17.6 0.1 0.0027 17.6 0.1 6.1 9 0 0 9 9 9 1 Leucine Rich repeat LRR_1 PF00560.33 KXG51363.1 - 1.5 9.6 3.8 56 4.9 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat SNF2_N PF00176.23 KXG51364.1 - 3.1e-50 170.9 1.7 2.9e-49 167.7 1.7 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXG51364.1 - 6e-17 62.0 0.0 3.5e-16 59.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG51364.1 - 9.6e-08 32.2 0.1 3.2e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KXG51364.1 - 2e-05 24.3 12.0 2e-05 24.3 12.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 KXG51364.1 - 0.0019 17.1 0.0 0.0046 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-C3HC4_3 PF13920.6 KXG51364.1 - 0.0022 17.8 11.0 0.0022 17.8 11.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KXG51364.1 - 0.0039 17.0 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 KXG51364.1 - 0.016 15.5 12.7 0.016 15.5 12.7 2.6 2 0 0 2 2 2 0 Ring finger domain Zn_Tnp_IS91 PF14319.6 KXG51364.1 - 0.13 12.3 18.1 0.053 13.6 5.6 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain C2 PF00168.30 KXG51365.1 - 1.8e-11 44.3 0.0 3.5e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain ArfGap PF01412.18 KXG51366.1 - 3.3e-34 117.5 0.1 3.3e-34 117.5 0.1 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KXG51366.1 - 4e-20 72.6 13.4 7e-20 71.7 13.4 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KXG51366.1 - 4.2e-12 46.5 0.3 2e-11 44.3 0.3 2.3 1 0 0 1 1 1 1 PH domain YTH PF04146.15 KXG51367.1 - 3e-61 206.2 0.0 5.2e-61 205.4 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 KXG51367.1 - 1.6e-07 31.1 0.0 3.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXG51367.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Sugar_tr PF00083.24 KXG51369.1 - 2.1e-136 455.4 27.5 2.4e-136 455.2 27.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG51369.1 - 2.3e-26 92.6 48.6 2.8e-21 75.8 24.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXG51369.1 - 3.4e-08 32.5 20.5 6.4e-05 21.7 1.8 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein Pox_A14 PF05767.12 KXG51369.1 - 0.0033 17.5 0.5 0.24 11.6 0.0 3.0 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 PI3_PI4_kinase PF00454.27 KXG51370.1 - 4.2e-39 134.9 0.0 4.3e-28 98.8 0.0 2.7 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KXG51370.1 - 1.1e-25 90.2 0.0 2.4e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 KXG51370.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Pkinase PF00069.25 KXG51371.1 - 1.3e-75 254.2 0.0 1.7e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG51371.1 - 6.2e-36 124.0 0.0 8.6e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KXG51371.1 - 7.4e-14 51.9 0.1 1.8e-13 50.6 0.1 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KXG51371.1 - 1.3e-10 41.1 0.0 1.6e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KXG51371.1 - 3.5e-07 29.3 0.2 1.4e-06 27.4 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 KXG51371.1 - 4.4e-05 23.7 0.0 9.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 KXG51371.1 - 0.00034 20.6 0.1 0.00076 19.5 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KXG51371.1 - 0.0018 18.0 0.1 0.43 10.2 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KXG51371.1 - 0.019 14.3 0.0 0.046 13.1 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.22 KXG51372.1 - 1.2e-76 258.4 0.0 1.5e-76 258.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cation_efflux PF01545.21 KXG51372.1 - 0.046 13.5 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Cation efflux family IGR PF09597.10 KXG51373.1 - 1.5e-23 82.6 0.6 2.5e-23 81.9 0.6 1.4 1 0 0 1 1 1 1 IGR protein motif Pkinase PF00069.25 KXG51374.1 - 5e-63 212.9 0.0 5.9e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG51374.1 - 4.5e-33 114.6 0.0 6.2e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG51374.1 - 0.0052 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXG51374.1 - 0.059 13.3 0.0 0.18 11.7 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinesin PF00225.23 KXG51375.1 - 1.6e-96 323.1 0.0 3.3e-96 322.1 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXG51375.1 - 7.2e-25 87.7 0.0 1.9e-24 86.3 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Lebercilin PF15619.6 KXG51375.1 - 0.0013 18.4 0.3 0.0013 18.4 0.3 2.4 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease PKcGMP_CC PF16808.5 KXG51375.1 - 0.003 17.4 3.7 0.14 12.0 0.5 3.1 3 0 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase DAGAT PF03982.13 KXG51376.1 - 2.5e-91 305.7 0.0 3e-91 305.4 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.13 KXG51376.1 - 0.063 13.0 0.6 0.12 12.1 0.6 1.4 1 0 0 1 1 1 0 Rer1 family G-patch PF01585.23 KXG51377.1 - 1e-05 25.3 0.1 0.00015 21.6 0.1 2.5 1 1 0 1 1 1 1 G-patch domain PPP4R2 PF09184.11 KXG51377.1 - 0.043 13.4 19.3 0.062 12.9 19.3 1.2 1 0 0 1 1 1 0 PPP4R2 LAP1C PF05609.12 KXG51377.1 - 0.36 9.9 16.7 0.47 9.5 16.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TFIIF_alpha PF05793.12 KXG51377.1 - 0.45 9.0 35.6 0.57 8.7 35.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Apt1 PF10351.9 KXG51377.1 - 0.6 8.9 26.8 0.77 8.5 26.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 KXG51377.1 - 0.64 7.1 13.9 0.81 6.7 13.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SAPS PF04499.15 KXG51377.1 - 1.2 7.9 11.5 1.6 7.5 11.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3807 PF12720.7 KXG51377.1 - 1.8 8.8 23.1 3.3 7.9 23.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Macoilin PF09726.9 KXG51377.1 - 1.8 7.0 21.6 2.3 6.7 21.6 1.1 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 KXG51377.1 - 3.3 5.9 23.3 4.6 5.4 23.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KXG51377.1 - 4 6.1 18.6 5 5.8 18.6 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KXG51377.1 - 7 6.4 21.4 11 5.7 21.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SOBP PF15279.6 KXG51377.1 - 7.2 7.1 20.2 10 6.7 20.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Syja_N PF02383.18 KXG51378.1 - 5.7e-72 242.7 0.0 7.6e-72 242.3 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 KXG51378.1 - 2.7e-11 43.4 0.1 5e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RAMP4 PF06624.12 KXG51379.1 - 1.5e-23 82.6 0.0 1.7e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Adaptin_N PF01602.20 KXG51380.1 - 1e-76 258.6 0.0 3.7e-71 240.3 0.0 2.0 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 KXG51380.1 - 1.8e-09 37.9 0.1 9.1e-07 29.1 0.0 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXG51380.1 - 1.1e-05 25.7 3.7 0.37 11.2 0.0 4.0 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 KXG51380.1 - 2.8e-05 24.0 2.9 0.08 13.2 0.1 4.8 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KXG51380.1 - 0.12 12.9 9.0 22 5.7 0.1 4.8 4 1 1 5 5 5 0 HEAT-like repeat TPR_17 PF13431.6 KXG51381.1 - 1.4e-05 25.1 0.1 0.063 13.7 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXG51381.1 - 1.5e-05 24.6 0.0 0.12 12.1 0.0 3.5 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.28 KXG51381.1 - 2.4e-05 23.9 0.0 0.00023 20.8 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXG51381.1 - 0.00018 21.5 0.1 0.00018 21.5 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXG51381.1 - 0.0004 21.0 0.6 0.022 15.5 0.1 6.1 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXG51381.1 - 0.0023 17.9 6.3 0.0037 17.3 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXG51381.1 - 0.079 13.0 1.5 3.1 8.0 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Asp-B-Hydro_N PF05279.11 KXG51381.1 - 7.5 6.5 10.9 13 5.8 10.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RNase_H PF00075.24 KXG51384.1 - 0.0021 18.3 0.0 0.0098 16.1 0.0 2.0 2 0 0 2 2 2 1 RNase H PfkB PF00294.24 KXG51385.1 - 1e-30 107.1 0.0 4.3e-30 105.1 0.0 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase p6 PF17548.2 KXG51385.1 - 0.03 14.3 0.0 0.094 12.7 0.0 1.8 2 0 0 2 2 2 0 Histone-like Protein p6 Tau95 PF09734.9 KXG51387.1 - 1.4e-36 126.4 0.1 5.2e-36 124.5 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KXG51387.1 - 6.4e-34 116.9 0.0 1.1e-33 116.1 0.0 1.4 1 0 0 1 1 1 1 Tau95 Triple barrel domain HD_3 PF13023.6 KXG51388.1 - 2.2e-21 76.5 0.1 3.5e-21 75.8 0.1 1.3 1 0 0 1 1 1 1 HD domain ADK PF00406.22 KXG51388.1 - 1.7e-07 31.5 0.0 2.4e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase HD_2 PF12917.7 KXG51388.1 - 0.00027 20.7 0.1 0.00049 19.9 0.1 1.5 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme B56 PF01603.20 KXG51390.1 - 3.9e-192 638.8 4.1 4.7e-192 638.5 4.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KXG51390.1 - 0.0046 16.9 0.9 0.8 9.6 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF810 PF05664.11 KXG51390.1 - 0.15 10.6 0.0 0.25 9.8 0.0 1.3 1 0 0 1 1 1 0 Plant family of unknown function (DUF810) AMP-binding PF00501.28 KXG51391.1 - 3.1e-147 490.6 0.0 2.5e-73 247.1 0.1 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KXG51391.1 - 2.1e-81 274.0 0.0 8e-47 159.9 0.0 4.1 3 2 0 3 3 3 2 Condensation domain PP-binding PF00550.25 KXG51391.1 - 5.5e-24 84.3 0.0 2.6e-11 43.7 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXG51391.1 - 1.4e-08 35.6 0.0 0.00038 21.4 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain p450 PF00067.22 KXG51392.1 - 3.9e-42 144.6 0.0 5e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.8 KXG51393.1 - 3.1e-94 316.4 0.0 3.5e-94 316.2 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase adh_short PF00106.25 KXG51394.1 - 4e-38 130.8 0.0 5.3e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG51394.1 - 1.5e-25 90.1 0.1 2e-25 89.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KXG51394.1 - 2e-06 27.4 0.0 3.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KXG51394.1 - 7.4e-05 22.7 0.1 0.00012 22.1 0.1 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KXG51394.1 - 0.011 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 KXG51394.1 - 0.039 13.4 0.0 0.066 12.7 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXG51394.1 - 0.12 11.9 0.1 0.23 11.0 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family MFS_1 PF07690.16 KXG51395.1 - 2.1e-42 145.3 44.4 2.1e-42 145.3 44.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG51395.1 - 1.2e-12 47.1 23.8 1.9e-12 46.4 23.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TPIP1 PF15338.6 KXG51395.1 - 0.066 13.3 0.2 0.16 12.1 0.2 1.6 1 0 0 1 1 1 0 p53-regulated apoptosis-inducing protein 1 Pkinase PF00069.25 KXG51396.1 - 3.3e-05 23.4 0.0 6.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG51396.1 - 0.088 12.1 0.0 0.27 10.5 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase FAT PF02259.23 KXG51397.1 - 3.5e-73 246.8 9.5 1.5e-72 244.7 8.9 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KXG51397.1 - 1.1e-34 120.4 0.1 2.4e-34 119.3 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KXG51397.1 - 1.7e-05 24.5 0.1 5e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.17 KXG51397.1 - 0.46 10.7 4.6 1.6 9.1 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF572 PF04502.13 KXG51398.1 - 2.6e-59 201.5 21.4 3.6e-59 201.1 21.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) ComFB PF10719.9 KXG51398.1 - 0.006 16.7 0.3 0.015 15.4 0.3 1.7 1 0 0 1 1 1 1 Late competence development protein ComFB TMEM210 PF15195.6 KXG51398.1 - 0.068 13.6 0.5 0.65 10.4 0.2 2.2 2 0 0 2 2 2 0 TMEM210 family Colicin PF01024.19 KXG51398.1 - 3.2 7.6 4.9 4.9 7.0 4.9 1.2 1 0 0 1 1 1 0 Colicin pore forming domain ANAPC3 PF12895.7 KXG51399.1 - 2.8e-28 98.0 9.4 4.8e-22 78.0 0.6 5.2 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KXG51399.1 - 4.5e-28 95.1 9.4 0.0086 16.1 0.2 10.8 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 KXG51399.1 - 6.3e-28 95.4 0.6 0.00044 19.9 0.3 10.4 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 KXG51399.1 - 5.5e-20 71.6 8.3 0.00047 20.6 0.0 7.4 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXG51399.1 - 3.4e-14 51.8 0.5 0.53 10.6 0.1 8.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXG51399.1 - 3.8e-14 52.7 23.4 0.00011 22.4 0.2 9.6 7 4 2 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXG51399.1 - 7.6e-13 48.1 13.8 2.3 9.2 0.3 10.2 8 3 3 11 11 10 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXG51399.1 - 1.9e-10 40.2 0.9 0.38 10.5 0.1 8.5 9 0 0 9 9 9 2 TPR repeat TPR_16 PF13432.6 KXG51399.1 - 3.3e-10 40.4 23.8 0.52 11.0 1.3 9.1 9 1 2 11 11 10 4 Tetratricopeptide repeat TPR_6 PF13174.6 KXG51399.1 - 1.5e-08 34.8 6.5 1.4 9.7 0.2 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXG51399.1 - 4.2e-08 32.7 17.0 1.7 8.8 0.0 9.8 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXG51399.1 - 8.3e-05 22.3 22.3 0.17 11.8 0.0 8.8 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXG51399.1 - 9.2e-05 22.6 0.6 5 7.7 0.0 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_21 PF09976.9 KXG51399.1 - 0.0042 16.8 2.7 7.2 6.3 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 KXG51399.1 - 0.0063 17.0 14.0 18 6.4 0.1 8.0 8 0 0 8 8 6 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KXG51399.1 - 0.0067 16.4 0.2 0.2 11.7 0.0 2.8 2 0 0 2 2 2 1 Putative TPR-like repeat TPR_9 PF13371.6 KXG51399.1 - 1.1 9.5 12.8 17 5.7 0.1 6.3 5 2 1 7 7 7 0 Tetratricopeptide repeat Glyco_transf_90 PF05686.12 KXG51400.1 - 3.9e-31 108.3 0.5 5.4e-31 107.9 0.5 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 p450 PF00067.22 KXG51401.1 - 3.5e-50 171.1 0.0 4.5e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4149 PF13664.6 KXG51402.1 - 3.8e-21 75.3 1.1 3.8e-21 75.3 1.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) bZIP_1 PF00170.21 KXG51403.1 - 0.0067 16.5 8.2 0.0097 16.0 8.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor DIT1_PvcA PF05141.12 KXG51404.1 - 1.2e-94 316.8 0.0 1.8e-94 316.3 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 KXG51404.1 - 1.2e-21 77.7 0.0 3.8e-21 76.1 0.0 1.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ALC PF17527.2 KXG51404.1 - 0.079 12.6 0.4 0.19 11.4 0.4 1.6 1 0 0 1 1 1 0 Phage ALC protein DJ-1_PfpI PF01965.24 KXG51405.1 - 8.2e-10 38.7 0.0 1.9e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KXG51405.1 - 0.017 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like Fungal_trans PF04082.18 KXG51406.1 - 4e-10 39.2 0.3 6.8e-10 38.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG51406.1 - 3.2e-06 27.2 12.0 5.8e-06 26.3 12.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SEP PF08059.13 KXG51407.1 - 1.6e-24 86.2 0.1 2.8e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.6 KXG51407.1 - 6.8e-14 51.4 0.4 1.1e-13 50.8 0.4 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KXG51407.1 - 7e-14 51.8 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 UBX domain TAP_C PF03943.13 KXG51407.1 - 0.0036 16.9 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 TAP C-terminal domain ParA PF10609.9 KXG51408.1 - 2.2e-84 282.7 0.1 1e-82 277.3 0.1 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXG51408.1 - 5.4e-10 39.4 0.0 3.3e-09 36.9 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KXG51408.1 - 9.4e-07 28.4 0.0 4.8e-06 26.1 0.0 1.8 1 1 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 KXG51408.1 - 1.4e-05 25.1 0.1 0.00022 21.2 0.1 2.0 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 KXG51408.1 - 0.00022 20.5 0.8 0.00036 19.8 0.8 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.6 KXG51408.1 - 0.0011 18.6 0.1 0.002 17.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 KXG51408.1 - 0.0012 18.4 0.2 0.0043 16.6 0.2 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 KXG51408.1 - 0.0032 17.3 1.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KXG51408.1 - 0.0048 15.9 0.5 0.007 15.4 0.5 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 KXG51408.1 - 0.079 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Fer4_NifH PF00142.18 KXG51408.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family PHO4 PF01384.20 KXG51409.1 - 2.8e-109 365.2 10.3 3.3e-109 365.0 10.3 1.0 1 0 0 1 1 1 1 Phosphate transporter family SpoVAB PF13782.6 KXG51409.1 - 4.5 7.6 8.0 1 9.7 0.6 3.2 3 0 0 3 3 3 0 Stage V sporulation protein AB polyprenyl_synt PF00348.17 KXG51410.1 - 1.8e-89 299.2 0.0 2.2e-89 298.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase RNase_H2-Ydr279 PF09468.10 KXG51410.1 - 0.0013 18.9 0.1 0.008 16.4 0.1 2.0 2 1 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain DUF2795 PF11387.8 KXG51410.1 - 0.071 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) ANAPC8 PF04049.13 KXG51411.1 - 4.2e-52 175.9 0.1 1.1e-51 174.6 0.1 1.7 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 KXG51411.1 - 1e-21 75.8 8.5 0.00042 20.0 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXG51411.1 - 1.8e-21 74.5 17.3 8e-05 22.6 0.0 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXG51411.1 - 9e-18 62.9 20.0 0.063 13.4 2.8 9.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXG51411.1 - 1.2e-14 53.8 18.9 0.0084 16.9 0.0 8.9 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 KXG51411.1 - 1.1e-11 44.2 1.6 2e-06 27.4 0.1 4.5 2 2 2 4 4 4 3 TPR repeat TPR_16 PF13432.6 KXG51411.1 - 1.8e-11 44.5 13.7 7e-05 23.4 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG51411.1 - 6.8e-10 39.0 18.2 0.083 13.1 0.2 6.4 7 0 0 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KXG51411.1 - 1.4e-09 37.9 10.0 0.00011 22.3 0.2 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXG51411.1 - 2.9e-09 36.6 4.5 1.8 9.1 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXG51411.1 - 7e-09 35.8 12.8 0.61 10.4 0.2 6.8 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXG51411.1 - 1.3e-07 31.2 9.8 0.29 11.2 0.1 6.5 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXG51411.1 - 8e-07 29.5 23.1 0.12 12.9 0.1 8.4 9 1 1 10 10 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXG51411.1 - 5.5e-05 23.5 21.3 1.9 9.3 0.4 8.7 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXG51411.1 - 0.0017 17.6 12.6 0.0019 17.5 2.1 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.10 KXG51411.1 - 0.0099 14.9 0.1 8.6 5.2 0.0 3.0 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) HrpB1_HrpK PF09613.10 KXG51411.1 - 0.012 15.2 0.1 0.063 12.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) PPR PF01535.20 KXG51411.1 - 0.38 11.1 1.5 46 4.6 0.0 4.3 5 0 0 5 5 4 0 PPR repeat TPR_10 PF13374.6 KXG51411.1 - 0.46 10.4 15.7 3.3 7.7 0.5 6.6 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXG51411.1 - 1.6 9.6 6.7 2.1 9.2 0.6 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat DNA_ligase_A_M PF01068.21 KXG51412.1 - 1.2e-23 83.9 0.0 2.5e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXG51412.1 - 8.5e-13 49.0 0.0 2.2e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus GEN1_C PF18380.1 KXG51412.1 - 0.013 16.3 0.7 7.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain p450 PF00067.22 KXG51413.1 - 4.6e-50 170.7 0.0 5.7e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 KXG51414.1 - 2e-24 86.6 0.2 4.3e-24 85.5 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LegC3_N PF18654.1 KXG51415.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain DUF3449 PF11931.8 KXG51416.1 - 1.3e-74 250.0 0.5 1.3e-74 250.0 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KXG51416.1 - 4e-25 88.1 1.9 5.1e-25 87.8 0.2 2.1 2 1 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KXG51416.1 - 1.8e-15 56.5 0.9 3.5e-15 55.6 0.9 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KXG51416.1 - 2.9e-09 37.0 4.7 3e-07 30.6 1.0 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXG51416.1 - 2.1e-08 34.2 4.9 1.6e-07 31.5 0.9 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding PRP9_N PF16958.5 KXG51416.1 - 0.00021 21.4 18.9 0.0004 20.4 3.7 3.3 3 1 1 4 4 4 2 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_2 PF12756.7 KXG51416.1 - 0.00076 19.8 1.4 0.014 15.7 0.1 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KXG51416.1 - 0.071 14.0 1.3 19 6.5 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-LYAR PF08790.11 KXG51416.1 - 0.1 12.5 0.2 0.26 11.2 0.2 1.7 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.26 KXG51416.1 - 1.5 9.4 5.1 7.9 7.2 0.5 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type DEAD PF00270.29 KXG51417.1 - 2.8e-41 141.2 0.2 4.9e-41 140.4 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG51417.1 - 1.6e-33 115.3 0.1 6.6e-33 113.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KXG51417.1 - 0.001 18.9 0.1 0.0015 18.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KXG51417.1 - 0.0049 16.9 0.0 0.0091 16.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXG51417.1 - 0.0082 16.5 0.1 0.069 13.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 KXG51417.1 - 0.058 13.4 0.5 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 KXG51417.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 KXG51417.1 - 0.086 13.1 0.7 0.36 11.1 0.7 1.9 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 KXG51418.1 - 3.6e-18 65.6 13.5 0.0018 19.1 0.3 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG51418.1 - 8.5e-12 45.2 6.4 0.055 13.8 0.1 5.6 1 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXG51418.1 - 0.0016 17.5 2.7 0.76 8.7 1.5 3.4 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXG51418.1 - 0.0031 16.2 0.2 0.0063 15.2 0.2 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 CLTH PF10607.9 KXG51418.1 - 0.0063 16.4 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain WD40_3 PF15911.5 KXG51418.1 - 0.038 14.0 0.1 0.73 9.9 0.0 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat IKI3 PF04762.12 KXG51418.1 - 0.053 11.5 0.1 0.39 8.6 0.0 2.2 2 1 0 2 2 2 0 IKI3 family Frtz PF11768.8 KXG51418.1 - 0.076 11.3 0.1 0.92 7.7 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF4221 PF13970.6 KXG51418.1 - 0.081 12.5 0.0 0.18 11.3 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4221) WD40_like PF17005.5 KXG51418.1 - 0.13 11.5 0.1 0.33 10.2 0.0 1.6 2 0 0 2 2 2 0 WD40-like domain ADH_N PF08240.12 KXG51419.1 - 0.0019 18.0 0.0 0.0063 16.4 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG51419.1 - 0.027 14.4 0.1 0.046 13.7 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Mem_trans PF03547.18 KXG51420.1 - 1.7e-13 49.7 9.1 1.3e-10 40.3 0.1 2.1 2 0 0 2 2 2 2 Membrane transport protein HpcH_HpaI PF03328.14 KXG51421.1 - 1e-34 119.6 0.0 1.3e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF2236 PF09995.9 KXG51423.1 - 3.9e-30 105.8 0.0 6.4e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) NADH-UOR_E PF16514.5 KXG51423.1 - 0.075 13.4 0.0 0.8 10.1 0.0 2.7 3 0 0 3 3 3 0 putative NADH-ubiquinone oxidoreductase chain E ATP-synt_ab PF00006.25 KXG51425.1 - 1.3e-109 364.9 0.0 1.8e-109 364.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KXG51425.1 - 4.3e-46 155.7 0.0 7.8e-46 154.9 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KXG51425.1 - 7.6e-17 61.6 0.9 1.5e-16 60.7 0.9 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KXG51425.1 - 0.087 12.0 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Dynamin_M PF01031.20 KXG51426.1 - 7.2e-101 337.1 0.1 7.2e-101 337.1 0.1 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KXG51426.1 - 4.4e-57 192.8 0.2 9.2e-57 191.7 0.2 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KXG51426.1 - 1.4e-30 105.2 4.3 1.4e-30 105.2 4.3 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXG51426.1 - 1.4e-05 25.1 0.7 0.00012 22.1 0.7 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KXG51426.1 - 0.033 13.9 2.5 3.9 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Thioredoxin_14 PF18402.1 KXG51426.1 - 0.09 12.7 0.2 0.99 9.3 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain CN_hydrolase PF00795.22 KXG51427.1 - 3e-34 118.5 0.0 3.9e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TrkH PF02386.16 KXG51428.1 - 2.1e-148 494.9 7.8 4.9e-148 493.7 1.8 2.1 2 0 0 2 2 2 2 Cation transport protein PH PF00169.29 KXG51430.1 - 5.6e-06 26.8 1.2 1.1e-05 25.8 1.2 1.4 1 0 0 1 1 1 1 PH domain TUG-UBL1 PF11470.8 KXG51430.1 - 0.0023 18.1 0.0 0.0052 17.0 0.0 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain RA PF00788.23 KXG51430.1 - 0.0068 17.0 0.0 0.026 15.2 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH_11 PF15413.6 KXG51430.1 - 0.21 12.1 1.9 0.47 10.9 1.9 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain RmlD_sub_bind PF04321.17 KXG51431.1 - 2.4e-56 191.0 0.0 3e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KXG51431.1 - 1.7e-24 86.6 0.0 2.8e-24 85.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXG51431.1 - 3.1e-12 46.2 0.2 7.5e-10 38.4 0.0 3.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXG51431.1 - 1.2e-11 44.1 0.1 2e-10 40.1 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXG51431.1 - 4.9e-11 42.3 0.2 5.9e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KXG51431.1 - 1e-09 38.3 0.1 1e-08 35.0 0.1 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KXG51431.1 - 0.13 12.2 0.0 22 4.9 0.1 2.3 2 0 0 2 2 2 0 KR domain FAD-oxidase_C PF02913.19 KXG51432.1 - 3e-60 203.9 0.0 4.5e-60 203.4 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXG51432.1 - 4.6e-36 123.6 0.3 8.7e-36 122.7 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pkinase PF00069.25 KXG51433.1 - 8e-70 235.2 0.0 1.1e-69 234.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG51433.1 - 5.9e-47 160.1 0.0 8.8e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXG51433.1 - 3.1e-05 22.9 0.0 6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXG51433.1 - 0.00023 20.6 0.0 0.0024 17.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.16 KXG51433.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Pkinase PF00069.25 KXG51434.1 - 8.3e-07 28.6 0.0 0.00015 21.3 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain DUF4048 PF13257.6 KXG51435.1 - 5.8e-81 272.1 20.7 5.8e-81 272.1 20.7 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF4048) E3_UbLigase_EDD PF11547.8 KXG51435.1 - 0.064 13.0 0.2 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 E3 ubiquitin ligase EDD Tim17 PF02466.19 KXG51436.1 - 2.7e-40 137.2 6.9 4.2e-40 136.6 6.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PALP PF00291.25 KXG51437.1 - 6.5e-68 229.3 0.1 7.7e-68 229.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cnd3 PF12719.7 KXG51438.1 - 3.6e-90 302.1 1.6 4.2e-89 298.6 0.1 2.8 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KXG51438.1 - 3.3e-05 24.2 6.7 0.00053 20.3 0.3 3.6 2 1 0 3 3 3 1 HEAT repeats HEAT PF02985.22 KXG51438.1 - 5.2e-05 23.1 7.2 0.39 11.1 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat MMS19_N PF14500.6 KXG51438.1 - 0.0075 15.9 0.4 1.6 8.2 0.1 3.3 3 2 1 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II Cnd1 PF12717.7 KXG51438.1 - 0.021 14.9 2.3 1.2 9.1 0.1 3.7 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF4521 PF15021.6 KXG51438.1 - 0.15 12.0 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) HEAT_EZ PF13513.6 KXG51438.1 - 0.23 12.0 3.1 23 5.6 0.1 4.5 3 1 1 4 4 4 0 HEAT-like repeat LID PF17916.1 KXG51438.1 - 0.85 9.3 5.0 0.77 9.5 0.1 3.0 3 0 0 3 3 3 0 LIM interaction domain (LID) zf-RanBP PF00641.18 KXG51440.1 - 1.2e-20 72.4 9.1 7.8e-11 41.1 1.5 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KXG51440.1 - 5.6e-08 32.5 0.0 1.9e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KXG51440.1 - 2.2e-06 28.3 0.0 3.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease zf-ribbon_3 PF13248.6 KXG51440.1 - 0.21 11.0 2.4 2.5 7.6 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KXG51440.1 - 0.6 10.2 5.1 2.9 8.0 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon Proteasome PF00227.26 KXG51441.1 - 5.4e-56 189.1 0.1 7.6e-56 188.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXG51441.1 - 8.4e-14 50.9 0.3 3e-13 49.2 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 KXG51441.1 - 0.024 14.5 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) zf-CHY PF05495.12 KXG51442.1 - 1e-11 45.2 22.1 1.9e-11 44.3 22.1 1.4 1 0 0 1 1 1 1 CHY zinc finger Zn-ribbon_8 PF09723.10 KXG51442.1 - 1.1 9.5 16.4 2.1 8.5 8.5 2.4 1 1 1 2 2 2 0 Zinc ribbon domain WD40 PF00400.32 KXG51443.1 - 0.86 10.6 4.1 6.7 7.8 1.1 3.7 3 1 0 3 3 3 0 WD domain, G-beta repeat Acetyltransf_3 PF13302.7 KXG51444.1 - 3.1e-18 66.8 0.0 3.5e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG51444.1 - 1.5e-08 34.9 0.0 5.9e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family FR47 PF08445.10 KXG51444.1 - 0.00014 21.8 0.0 0.2 11.6 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_8 PF13523.6 KXG51444.1 - 0.037 13.7 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXG51444.1 - 0.058 13.8 0.0 0.77 10.2 0.0 2.2 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain DUF3328 PF11807.8 KXG51445.1 - 1.2e-46 159.3 0.4 1.5e-46 159.0 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glu-tRNAGln PF02686.15 KXG51445.1 - 0.073 13.4 0.1 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF1925 PF09094.11 KXG51446.1 - 3.3e-10 40.1 1.8 40 4.6 0.0 7.8 8 0 0 8 8 8 0 Domain of unknown function (DUF1925) Kelch_3 PF13415.6 KXG51446.1 - 9e-05 22.7 11.2 40 4.7 0.0 7.1 1 1 7 8 8 8 0 Galactose oxidase, central domain Alveol-reg_P311 PF11092.8 KXG51446.1 - 0.00021 21.4 6.9 39 4.5 0.0 6.6 1 1 6 7 7 7 0 Neuronal protein 3.1 (p311) He_PIG_assoc PF10632.9 KXG51446.1 - 0.082 12.6 17.4 1.5e+02 2.2 0.0 7.9 8 0 0 8 8 8 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Syndecan PF01034.20 KXG51446.1 - 0.11 12.4 27.1 38 4.3 0.2 7.2 1 1 6 7 7 7 0 Syndecan domain SAM35 PF10806.8 KXG51446.1 - 0.23 11.7 8.3 12 6.1 0.5 3.3 1 1 3 4 4 4 0 SAM35, subunit of SAM coomplex Fip1 PF05182.13 KXG51446.1 - 0.43 10.1 12.0 2.3e+02 1.4 0.0 7.0 8 0 0 8 8 8 0 Fip1 motif Polbeta PF18765.1 KXG51446.1 - 2.2 8.4 17.2 1e+02 3.1 0.0 6.9 1 1 6 7 7 7 0 Polymerase beta, Nucleotidyltransferase Chitin_bind_4 PF00379.23 KXG51446.1 - 4.8 7.8 32.7 49 4.6 0.2 7.5 1 1 3 4 4 4 0 Insect cuticle protein DUF3328 PF11807.8 KXG51447.1 - 1.1e-45 156.1 0.8 1.4e-45 155.8 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_S10 PF00450.22 KXG51448.1 - 3.4e-67 227.7 0.6 1.3e-66 225.8 0.6 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase Melibiase_2 PF16499.5 KXG51449.1 - 8.2e-59 199.1 7.5 8.9e-39 133.3 1.0 2.4 2 1 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KXG51449.1 - 5.5e-12 45.6 1.6 3.3e-11 43.1 0.2 2.3 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KXG51449.1 - 3.7e-08 32.7 0.0 7.3e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Melibiase Peptidase_M28 PF04389.17 KXG51450.1 - 0.063 13.0 0.4 0.11 12.1 0.4 1.3 1 0 0 1 1 1 0 Peptidase family M28 DUF3431 PF11913.8 KXG51451.1 - 1.4e-71 240.7 0.0 1.8e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) F-box-like PF12937.7 KXG51452.1 - 7.5e-06 25.7 1.5 1.2e-05 25.0 0.1 2.2 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KXG51452.1 - 0.048 14.1 1.2 7.4 7.1 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KXG51452.1 - 0.13 12.2 2.1 1.8 8.5 2.1 2.7 1 1 0 1 1 1 0 F-box domain NPP1 PF05630.11 KXG51453.1 - 5.8e-05 23.3 1.9 0.00035 20.8 1.5 2.0 1 1 1 2 2 2 1 Necrosis inducing protein (NPP1) Glyco_hydro_32N PF00251.20 KXG51454.1 - 4.9e-92 308.7 4.8 6.4e-92 308.4 4.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KXG51454.1 - 2.2e-28 99.3 0.2 4.4e-28 98.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Sortilin-Vps10 PF15902.5 KXG51454.1 - 0.02 13.7 1.0 0.16 10.7 0.1 2.3 1 1 1 2 2 2 0 Sortilin, neurotensin receptor 3, CHB_HEX_C PF03174.13 KXG51454.1 - 0.03 14.3 0.1 0.1 12.6 0.1 1.8 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain HofP PF10748.9 KXG51454.1 - 0.099 12.2 1.1 0.44 10.1 1.1 2.0 1 1 0 1 1 1 0 DNA utilization proteins HofP Lactamase_B PF00753.27 KXG51455.1 - 8.2e-19 68.4 2.4 1.1e-18 67.9 2.4 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXG51455.1 - 4.1e-05 23.2 0.2 6.3e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain UPF0047 PF01894.17 KXG51456.1 - 1.8e-37 128.0 0.0 2.1e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CHCC PF10276.9 KXG51457.1 - 7.4e-17 61.1 1.1 1.3e-16 60.4 1.1 1.4 1 0 0 1 1 1 1 Zinc-finger domain MPP6 PF10175.9 KXG51458.1 - 3.3e-05 24.4 16.8 0.0034 17.9 16.8 2.9 1 1 0 1 1 1 1 M-phase phosphoprotein 6 CoaE PF01121.20 KXG51459.1 - 3.9e-42 143.9 0.0 5.7e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KXG51459.1 - 0.0056 17.2 0.3 0.48 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Molydop_binding PF01568.21 KXG51459.1 - 0.025 14.6 0.2 0.038 14.0 0.2 1.3 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain 2TM PF13239.6 KXG51459.1 - 0.061 13.6 0.3 0.12 12.7 0.3 1.5 1 0 0 1 1 1 0 2TM domain DUF3431 PF11913.8 KXG51460.1 - 1.2e-88 296.5 0.2 2.4e-88 295.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) Lipase_3 PF01764.25 KXG51460.1 - 2.9e-33 114.7 0.0 4.9e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KXG51460.1 - 8.1e-07 29.0 0.3 2e-06 27.7 0.3 1.7 1 0 0 1 1 1 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 KXG51460.1 - 1.2e-05 24.7 0.0 1.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KXG51460.1 - 0.00047 19.8 0.1 0.0012 18.5 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_6 PF12697.7 KXG51460.1 - 0.045 14.4 0.2 0.12 13.0 0.2 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family VirJ PF06057.11 KXG51460.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Thioesterase PF00975.20 KXG51460.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain NUDIX_2 PF13869.6 KXG51461.1 - 8.3e-81 270.1 0.0 9.9e-81 269.8 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Peptidase_M16_M PF16187.5 KXG51462.1 - 1.3e-97 326.5 1.8 2.4e-97 325.6 1.8 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KXG51462.1 - 1.6e-33 116.2 0.5 1.5e-21 77.2 0.0 4.6 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXG51462.1 - 4.9e-32 111.0 5.9 6.2e-31 107.4 2.5 3.6 2 2 1 3 3 3 1 Insulinase (Peptidase family M16) Bac_thur_toxin PF01338.18 KXG51462.1 - 0.098 12.1 0.0 5.7 6.3 0.0 2.7 2 0 0 2 2 2 0 Bacillus thuringiensis toxin Bys1 PF04681.12 KXG51463.1 - 4.7e-16 59.1 1.7 5.6e-16 58.9 1.7 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Thermopsin PF05317.11 KXG51463.1 - 0.019 14.4 0.0 0.023 14.2 0.0 1.1 1 0 0 1 1 1 0 Thermopsin Arb2 PF09757.9 KXG51464.1 - 3e-98 328.1 0.0 4e-98 327.7 0.0 1.1 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 KXG51464.1 - 2.8e-85 286.5 0.0 4.7e-85 285.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Gp_dh_C PF02800.20 KXG51465.1 - 6e-72 240.4 0.0 8.5e-72 239.9 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KXG51465.1 - 7.9e-39 132.1 0.2 2.6e-38 130.4 0.1 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KXG51465.1 - 0.0039 17.3 0.1 0.015 15.4 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KXG51465.1 - 0.14 11.5 0.1 0.41 10.0 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pho88 PF10032.9 KXG51466.1 - 3.3e-79 264.4 0.1 3.7e-79 264.2 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Histone PF00125.24 KXG51467.1 - 1.1e-16 61.4 0.0 1.4e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KXG51467.1 - 1e-11 44.3 0.0 2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KXG51467.1 - 3.5e-05 24.0 0.0 4.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.22 KXG51468.1 - 9.4e-11 41.5 0.1 1.7e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KXG51468.1 - 5.1e-06 26.2 0.1 9.5e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ-C PF12901.7 KXG51468.1 - 0.00085 19.3 4.9 0.0032 17.5 4.9 2.1 1 0 0 1 1 1 1 SUZ-C motif DUF3431 PF11913.8 KXG51469.1 - 1.8e-80 269.8 0.3 2.4e-80 269.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Sporozoite_P67 PF05642.11 KXG51470.1 - 0.00036 18.8 8.1 0.00065 17.9 8.1 1.3 1 0 0 1 1 1 1 Sporozoite P67 surface antigen PI3K_1B_p101 PF10486.9 KXG51470.1 - 0.34 8.6 8.0 0.41 8.4 8.0 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFIIF_alpha PF05793.12 KXG51470.1 - 0.4 9.2 13.0 0.49 8.9 13.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 KXG51470.1 - 0.41 9.9 8.9 0.47 9.7 8.9 1.1 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.9 KXG51470.1 - 0.9 8.0 7.6 1 7.8 7.6 1.0 1 0 0 1 1 1 0 Macoilin family DNA_pol_phi PF04931.13 KXG51470.1 - 1.2 7.2 4.7 1.4 7.0 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KXG51470.1 - 3.5 5.7 7.3 4 5.5 7.3 1.0 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.6 KXG51470.1 - 3.5 8.0 12.3 8.2 6.9 12.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 KXG51470.1 - 4.1 7.1 8.5 12 5.6 8.5 1.8 1 1 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.12 KXG51470.1 - 5.6 6.6 14.1 0.6 9.8 9.8 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.9 KXG51470.1 - 5.9 6.4 10.7 8.7 5.9 10.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hid1 PF12722.7 KXG51470.1 - 6.5 4.8 5.6 8 4.4 5.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 KXG51470.1 - 6.7 3.7 6.5 7.4 3.5 6.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SSP160 PF06933.11 KXG51470.1 - 7 4.7 27.0 9.1 4.3 27.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Apt1 PF10351.9 KXG51470.1 - 7.5 5.3 10.7 9.3 5.0 10.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Aldo_ket_red PF00248.21 KXG51471.1 - 2.7e-13 49.8 0.0 2.2e-12 46.8 0.0 2.1 1 1 1 2 2 2 1 Aldo/keto reductase family HSF_DNA-bind PF00447.17 KXG51472.1 - 1.3e-28 99.4 0.2 2.7e-28 98.4 0.2 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 KXG51472.1 - 0.064 13.7 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Ets-domain TMF_DNA_bd PF12329.8 KXG51472.1 - 0.16 12.0 1.2 2 8.5 0.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Pro_isomerase PF00160.21 KXG51474.1 - 1.3e-39 136.0 0.0 2.4e-39 135.1 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 KXG51474.1 - 0.0079 16.6 0.1 0.0079 16.6 0.1 3.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4604) Clr5 PF14420.6 KXG51475.1 - 5.5e-08 32.9 0.1 1.2e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 Clr5 domain HTH_Tnp_Tc3_2 PF01498.18 KXG51475.1 - 2.2e-05 24.6 1.2 0.0048 17.1 0.4 2.2 2 0 0 2 2 2 2 Transposase HTH_21 PF13276.6 KXG51475.1 - 0.0046 17.1 1.4 0.17 12.0 0.3 2.5 2 1 0 2 2 2 1 HTH-like domain HTH_32 PF13565.6 KXG51475.1 - 0.013 16.1 0.4 0.5 11.0 0.1 2.4 1 1 1 2 2 2 0 Homeodomain-like domain HTH_12 PF08461.10 KXG51475.1 - 0.051 13.5 1.8 2.6 8.1 0.2 2.4 1 1 2 3 3 3 0 Ribonuclease R winged-helix domain SPK PF04435.18 KXG51475.1 - 0.13 12.7 0.4 0.35 11.3 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF545) Rep_fac_C PF08542.11 KXG51476.1 - 1e-17 64.3 0.0 3.5e-16 59.4 0.0 2.7 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 KXG51476.1 - 7.9e-16 58.7 0.0 1.5e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KXG51476.1 - 5.5e-12 45.8 0.0 1.4e-11 44.5 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit His_Phos_2 PF00328.22 KXG51476.1 - 8.9e-10 38.5 0.0 9e-08 31.9 0.0 2.5 2 1 1 3 3 3 1 Histidine phosphatase superfamily (branch 2) Rad17 PF03215.15 KXG51476.1 - 3.8e-08 33.5 0.0 1.6e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KXG51476.1 - 3.4e-06 27.3 0.0 1.1e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 AAA C-terminal domain AAA_30 PF13604.6 KXG51476.1 - 1.1e-05 25.3 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXG51476.1 - 1.7e-05 25.3 0.1 0.00019 21.9 0.0 2.4 2 1 0 2 2 1 1 AAA ATPase domain AAA_11 PF13086.6 KXG51476.1 - 2.8e-05 24.0 0.1 0.00021 21.2 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXG51476.1 - 4.2e-05 23.8 0.1 0.00032 21.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 KXG51476.1 - 5.3e-05 23.1 0.0 9.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.14 KXG51476.1 - 7.1e-05 22.8 0.0 0.00024 21.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KXG51476.1 - 0.00013 21.8 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXG51476.1 - 0.00018 21.3 0.0 0.00093 19.0 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KXG51476.1 - 0.00022 20.5 0.0 0.00041 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KXG51476.1 - 0.00065 20.1 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXG51476.1 - 0.0012 18.9 0.0 0.003 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KXG51476.1 - 0.002 18.0 0.0 0.0068 16.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KXG51476.1 - 0.004 16.6 0.3 2 7.8 0.0 2.4 1 1 1 2 2 2 2 PhoH-like protein RNA_helicase PF00910.22 KXG51476.1 - 0.0055 17.1 0.1 0.32 11.4 0.0 3.3 3 0 0 3 3 3 1 RNA helicase Sigma54_activat PF00158.26 KXG51476.1 - 0.025 14.3 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 KXG51476.1 - 0.038 14.2 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXG51476.1 - 0.044 14.3 0.0 0.087 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXG51476.1 - 0.045 13.3 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 1 0 P-loop containing dynein motor region TniB PF05621.11 KXG51476.1 - 0.057 12.8 0.0 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein DEAD PF00270.29 KXG51476.1 - 0.058 13.2 0.0 0.29 10.9 0.0 2.0 1 1 1 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.15 KXG51476.1 - 0.12 12.3 0.0 0.5 10.3 0.0 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KXG51476.1 - 0.15 11.6 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KXG51476.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) P21-Arc PF04062.14 KXG51477.1 - 1.7e-72 243.1 0.0 1.9e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.13 KXG51478.1 - 3.6e-117 390.8 0.0 4.4e-117 390.5 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family AnmK PF03702.14 KXG51478.1 - 0.062 12.4 0.0 5.8 5.9 0.0 2.1 1 1 1 2 2 2 0 Anhydro-N-acetylmuramic acid kinase MINDY_DUB PF04424.13 KXG51479.1 - 1.6e-18 66.8 0.0 2.7e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase Cellulase PF00150.18 KXG51480.1 - 2e-39 135.7 1.3 7e-39 133.9 0.5 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 KXG51480.1 - 1.2e-22 79.8 11.7 2.1e-22 79.0 0.7 3.7 3 1 0 3 3 3 2 Carbohydrate binding domain X2 CBM_1 PF00734.18 KXG51480.1 - 8.7e-12 44.8 14.9 2.3e-11 43.4 14.9 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain RSN1_7TM PF02714.15 KXG51481.1 - 1e-83 280.8 22.5 1.4e-83 280.4 22.5 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KXG51481.1 - 7.6e-32 111.0 1.3 7.6e-32 111.0 1.3 1.6 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KXG51481.1 - 8.8e-30 102.7 0.7 2.5e-29 101.3 0.7 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DUF4164 PF13747.6 KXG51481.1 - 0.035 14.4 3.0 3 8.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) kleA_kleC PF17383.2 KXG51481.1 - 0.05 13.9 1.1 0.13 12.6 0.1 2.2 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A RRM_1 PF00076.22 KXG51481.1 - 0.075 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 4HBT PF03061.22 KXG51482.1 - 7.3e-13 48.7 0.9 1.2e-12 48.0 0.9 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KXG51482.1 - 0.097 12.8 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) PIG-P PF08510.12 KXG51483.1 - 1.9e-53 179.5 2.2 3.1e-53 178.8 2.2 1.3 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KXG51483.1 - 0.17 12.2 9.1 0.28 11.5 9.1 1.2 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) XPA_C PF05181.12 KXG51484.1 - 9.2e-20 70.4 5.2 3.3e-12 46.2 0.1 2.5 2 0 0 2 2 2 2 XPA protein C-terminus YhfH PF14149.6 KXG51484.1 - 0.037 14.0 5.1 1 9.4 0.7 2.6 2 0 0 2 2 2 0 YhfH-like protein XPA_N PF01286.18 KXG51484.1 - 2 8.6 13.2 0.72 9.9 7.3 2.3 2 0 0 2 2 2 0 XPA protein N-terminal Striatin PF08232.12 KXG51485.1 - 1.1e-42 146.2 4.6 1.1e-42 146.2 4.6 2.2 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 KXG51485.1 - 3.3e-24 84.7 21.3 4.8e-05 24.0 0.0 8.2 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG51485.1 - 0.00011 22.4 0.2 0.14 12.5 0.0 4.3 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXG51485.1 - 0.00097 19.1 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A CALCOCO1 PF07888.11 KXG51485.1 - 0.0022 17.0 4.4 0.0048 15.8 4.4 1.5 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like PD40 PF07676.12 KXG51485.1 - 0.0093 15.9 0.0 1.8 8.6 0.1 2.9 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KXG51485.1 - 0.03 12.9 0.0 0.069 11.7 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain CENP-Q PF13094.6 KXG51485.1 - 0.044 14.0 9.6 0.095 12.9 9.4 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Blt1 PF12754.7 KXG51486.1 - 1e-68 230.4 0.2 1.3e-68 230.0 0.2 1.1 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 KXG51486.1 - 3.7e-26 90.5 0.1 7.3e-26 89.5 0.1 1.5 1 0 0 1 1 1 1 Get5 carboxyl domain Methyltr_RsmB-F PF01189.17 KXG51487.1 - 3e-72 242.5 0.0 5.6e-72 241.6 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KXG51487.1 - 9.4e-08 32.5 0.0 3e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 KXG51487.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 KXG51487.1 - 0.036 13.8 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MORN PF02493.20 KXG51488.1 - 3.4e-15 54.9 21.7 0.00011 21.9 0.6 4.8 4 0 0 4 4 4 4 MORN repeat zf-C3HC4_3 PF13920.6 KXG51488.1 - 3.9e-10 39.4 11.1 6.2e-10 38.8 11.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.29 KXG51488.1 - 1.3e-09 38.0 0.0 2.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Prok-RING_4 PF14447.6 KXG51488.1 - 0.0016 18.3 10.7 0.003 17.4 10.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXG51488.1 - 3.8 7.5 11.9 7.2 6.7 11.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DS PF01916.17 KXG51489.1 - 5.4e-119 396.7 0.0 6.1e-119 396.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Myb_DNA-binding PF00249.31 KXG51491.1 - 7.6e-09 35.6 0.0 2.1e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KXG51491.1 - 0.041 13.8 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 Myb DNA-binding like p450 PF00067.22 KXG51492.1 - 1.6e-62 211.7 0.0 2e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KXG51493.1 - 2.4e-10 39.9 0.1 4.7e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXG51494.1 - 1.7e-40 139.1 23.6 2.1e-40 138.7 23.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_43 PF04616.14 KXG51495.1 - 1.9e-71 240.7 0.4 2.6e-71 240.3 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXG51495.1 - 3.4e-16 59.6 0.1 5.5e-16 58.9 0.1 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF5038 PF16441.5 KXG51495.1 - 0.12 12.4 0.4 0.21 11.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5038) Amidohydro_3 PF07969.11 KXG51496.1 - 1.4e-72 245.7 0.0 1.6e-72 245.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXG51496.1 - 3.5e-11 43.0 0.0 1.3e-06 27.9 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Oxidored_FMN PF00724.20 KXG51498.1 - 2.2e-60 204.8 0.0 9.2e-60 202.7 0.0 1.8 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1524 PF07510.11 KXG51499.1 - 2.1e-10 40.6 0.0 2.5e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 KXG51499.1 - 0.3 11.0 0.8 0.71 9.8 0.8 1.7 1 1 0 1 1 1 0 HNH endonuclease MFS_1 PF07690.16 KXG51500.1 - 2.2e-27 96.0 27.4 2.2e-27 96.0 27.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily GFO_IDH_MocA PF01408.22 KXG51501.1 - 3.9e-18 66.4 0.0 6.3e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KXG51501.1 - 0.0022 18.4 0.0 0.0046 17.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ABC_membrane PF00664.23 KXG51504.1 - 2.2e-98 329.3 36.1 5.6e-51 173.8 9.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXG51504.1 - 2.1e-71 238.8 0.0 4.1e-34 118.0 0.0 3.0 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 KXG51504.1 - 1.5e-12 47.4 0.0 0.00081 18.9 0.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXG51504.1 - 2.3e-06 28.1 3.5 0.069 13.5 0.3 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KXG51504.1 - 5.6e-06 26.0 0.4 0.059 13.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KXG51504.1 - 5.8e-06 25.4 1.3 0.083 11.7 0.1 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KXG51504.1 - 6.7e-06 26.1 0.1 0.24 11.3 0.0 3.1 3 0 0 3 3 2 2 RsgA GTPase AAA_15 PF13175.6 KXG51504.1 - 1.8e-05 24.6 0.0 0.017 14.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXG51504.1 - 2e-05 24.9 1.7 0.54 10.5 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KXG51504.1 - 8.1e-05 22.6 2.6 0.069 12.9 0.1 3.9 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KXG51504.1 - 0.00038 20.9 2.0 4.3 7.8 0.2 4.8 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 KXG51504.1 - 0.00057 19.7 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 KXG51504.1 - 0.00061 19.5 0.4 1.8 8.1 0.0 3.1 3 0 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 KXG51504.1 - 0.0008 20.0 0.0 1 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KXG51504.1 - 0.00099 18.4 0.0 0.25 10.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.14 KXG51504.1 - 0.001 19.0 0.2 3.4 7.7 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KXG51504.1 - 0.0013 19.3 0.3 0.63 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXG51504.1 - 0.0013 19.0 0.4 1.8 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KXG51504.1 - 0.0023 18.1 4.2 0.67 10.2 0.5 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 KXG51504.1 - 0.0023 17.7 0.1 0.36 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dala_Dala_lig_N PF01820.21 KXG51504.1 - 0.0046 17.4 0.1 8.6 6.9 0.0 3.2 3 0 0 3 3 2 0 D-ala D-ala ligase N-terminus AAA_14 PF13173.6 KXG51504.1 - 0.0047 17.0 0.0 9.2 6.3 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KXG51504.1 - 0.0053 16.5 3.8 1.1 9.0 0.3 3.7 3 1 0 3 3 3 1 AAA domain DUF87 PF01935.17 KXG51504.1 - 0.0062 16.7 0.6 1.9 8.6 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain Mg_chelatase PF01078.21 KXG51504.1 - 0.0075 15.7 0.0 0.67 9.3 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXG51504.1 - 0.012 15.7 0.0 4.3 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXG51504.1 - 0.015 15.3 1.4 5.3 7.2 0.0 3.5 3 0 0 3 3 3 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KXG51504.1 - 0.019 15.4 0.0 12 6.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.20 KXG51504.1 - 0.021 14.8 0.6 9.9 6.0 0.0 3.0 3 0 0 3 3 3 0 Adenylylsulphate kinase NB-ARC PF00931.22 KXG51504.1 - 0.021 14.0 0.6 3.9 6.6 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 KXG51504.1 - 0.024 14.2 5.7 0.17 11.4 0.0 3.4 4 0 0 4 4 3 0 AAA domain Rad17 PF03215.15 KXG51504.1 - 0.025 14.5 0.1 1.4 8.8 0.0 2.6 3 0 0 3 3 2 0 Rad17 P-loop domain AAA_7 PF12775.7 KXG51504.1 - 0.08 12.4 0.1 3 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region G-alpha PF00503.20 KXG51504.1 - 0.12 11.5 0.1 4.1 6.5 0.0 2.5 3 0 0 3 3 3 0 G-protein alpha subunit ATPase PF06745.13 KXG51504.1 - 0.23 10.8 1.4 0.68 9.2 0.1 2.2 2 0 0 2 2 2 0 KaiC Condensation PF00668.20 KXG51505.1 - 9.8e-87 291.5 0.0 1.2e-86 291.2 0.0 1.0 1 0 0 1 1 1 1 Condensation domain Thioesterase PF00975.20 KXG51506.1 - 3.8e-15 56.6 0.0 6.7e-15 55.8 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KXG51506.1 - 0.00011 22.9 0.2 0.00014 22.5 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KXG51506.1 - 0.004 17.0 0.0 0.0062 16.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG51506.1 - 0.13 11.5 0.0 0.39 9.9 0.0 1.7 1 1 1 2 2 2 0 Serine aminopeptidase, S33 DUF726 PF05277.12 KXG51506.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF3435 PF11917.8 KXG51509.1 - 2.1e-13 50.0 1.1 2.4e-08 33.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3435) FOXP-CC PF16159.5 KXG51509.1 - 0.19 12.4 1.8 0.6 10.8 1.8 1.8 1 0 0 1 1 1 0 FOXP coiled-coil domain FAD_binding_3 PF01494.19 KXG51510.1 - 3.9e-16 59.2 0.1 6.1e-16 58.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG51510.1 - 3.6e-05 23.2 0.4 0.007 15.6 0.1 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG51510.1 - 0.002 18.3 0.7 0.0058 16.8 0.1 2.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXG51510.1 - 0.0047 17.5 0.1 0.034 14.7 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG51510.1 - 0.0052 16.4 0.0 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXG51510.1 - 0.0097 15.9 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding ApbA PF02558.16 KXG51510.1 - 0.042 13.5 0.1 0.093 12.4 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 KXG51510.1 - 0.067 12.0 0.5 0.17 10.7 0.1 1.9 1 1 1 2 2 2 0 Tryptophan halogenase Ldh_1_N PF00056.23 KXG51510.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KXG51511.1 - 6.8e-15 54.8 0.7 1e-14 54.2 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG51511.1 - 1.9e-08 34.3 9.5 3.7e-08 33.4 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gelsolin PF00626.22 KXG51512.1 - 1.5e-36 124.1 0.7 3.3e-13 49.3 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat Romo1 PF10247.9 KXG51513.1 - 0.015 15.7 0.6 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Lipase_GDSL_2 PF13472.6 KXG51514.1 - 2.1e-14 54.4 0.2 3e-14 53.8 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXG51514.1 - 1.7e-09 37.9 0.1 2.5e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KXG51514.1 - 0.0026 17.9 0.3 0.011 15.9 0.3 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Herpes_capsid PF06112.11 KXG51515.1 - 1.7 8.6 7.5 2.9 7.9 7.5 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ATP-grasp_2 PF08442.10 KXG51516.1 - 8.8e-55 185.4 0.0 1.5e-54 184.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KXG51516.1 - 9.9e-19 67.7 1.1 1.9e-18 66.8 1.1 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KXG51516.1 - 1.5e-10 41.0 0.0 3.3e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KXG51516.1 - 0.001 18.6 0.1 0.0034 16.9 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 KXG51516.1 - 0.015 15.1 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 KXG51516.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Methyltransf_23 PF13489.6 KXG51517.1 - 4.3e-11 42.9 0.0 7.3e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG51517.1 - 1.3e-08 35.4 0.0 4.4e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG51517.1 - 1.9e-05 25.2 0.0 5.5e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG51517.1 - 4.1e-05 24.3 0.0 0.00063 20.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXG51517.1 - 0.00039 19.9 0.0 0.00094 18.7 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 KXG51517.1 - 0.0012 18.7 0.0 0.0059 16.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXG51517.1 - 0.0034 16.7 0.0 0.012 14.9 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KXG51517.1 - 0.027 14.0 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF4357 PF14267.6 KXG51517.1 - 0.12 12.4 0.2 0.71 9.9 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4357) Ank_2 PF12796.7 KXG51518.1 - 1.1e-67 224.6 0.7 2.2e-16 60.2 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG51518.1 - 8.3e-44 147.4 3.2 5.3e-10 39.6 0.0 7.7 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG51518.1 - 1.2e-37 123.6 0.6 0.00028 21.1 0.0 9.1 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 KXG51518.1 - 4.6e-35 118.5 0.0 0.00039 20.8 0.0 8.6 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KXG51518.1 - 5.3e-30 103.1 0.1 1.2e-07 31.9 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 KXG51519.1 - 1.3e-13 50.8 0.0 1.9e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily AA_permease_2 PF13520.6 KXG51520.1 - 8.2e-58 196.2 50.7 9.9e-58 195.9 50.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG51520.1 - 4.1e-23 81.7 38.7 5.5e-23 81.3 38.7 1.0 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_4 PF13420.7 KXG51521.1 - 1e-05 25.7 0.0 0.0043 17.2 0.0 2.4 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG51521.1 - 0.056 13.7 0.0 0.078 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF2156 PF09924.9 KXG51523.1 - 1.1e-26 93.5 0.0 1.6e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Ribosomal_L34 PF00468.17 KXG51523.1 - 2.5 8.1 6.9 0.56 10.2 2.6 2.1 2 0 0 2 2 2 0 Ribosomal protein L34 PX PF00787.24 KXG51524.1 - 1e-18 67.3 0.0 1.7e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 PX domain adh_short PF00106.25 KXG51526.1 - 4.9e-30 104.4 0.7 2.9e-21 75.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXG51526.1 - 1.8e-25 89.9 0.1 3.1e-23 82.6 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG51526.1 - 0.00015 21.7 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXG51526.1 - 0.0026 17.2 0.0 0.005 16.2 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KXG51526.1 - 0.068 13.1 1.9 1.2 9.0 1.9 2.2 1 1 0 1 1 1 0 NAD(P)H-binding RPN7 PF10602.9 KXG51527.1 - 8.9e-51 172.0 0.1 1.7e-50 171.2 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KXG51527.1 - 1.3e-09 38.5 0.0 8.8e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 PCI domain Imm5 PF14423.6 KXG51527.1 - 0.024 14.9 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 Immunity protein Imm5 PilJ PF13675.6 KXG51527.1 - 0.071 13.1 1.2 0.2 11.7 0.1 2.3 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term TPR_2 PF07719.17 KXG51527.1 - 1.6 9.0 4.4 0.9 9.8 0.1 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat p450 PF00067.22 KXG51528.1 - 1e-66 225.6 0.0 1.3e-66 225.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 KXG51528.1 - 7e-21 74.8 0.0 1.3e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG51528.1 - 1.4e-09 38.6 0.0 3.7e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG51528.1 - 6.7e-08 33.2 0.0 3.5e-07 30.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG51528.1 - 1.5e-07 31.9 0.0 3.6e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG51528.1 - 0.0034 17.2 0.0 0.051 13.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXG51528.1 - 0.09 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 KXG51528.1 - 0.19 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase TPR_10 PF13374.6 KXG51529.1 - 7.1e-39 130.6 43.7 8.3e-07 28.7 0.0 17.2 18 2 0 18 18 18 9 Tetratricopeptide repeat CHAT PF12770.7 KXG51529.1 - 5.8e-35 121.1 1.7 7.5e-35 120.7 0.4 1.8 2 0 0 2 2 2 1 CHAT domain TPR_14 PF13428.6 KXG51529.1 - 1e-10 41.5 45.8 0.2 12.6 0.7 15.6 14 3 3 17 17 17 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXG51529.1 - 5.6e-08 32.3 11.4 92 3.5 0.0 13.3 16 0 0 16 16 16 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXG51529.1 - 1.7e-05 25.0 32.1 3.6 8.0 0.0 13.8 10 6 5 15 15 15 2 Tetratricopeptide repeat Laminin_II PF06009.12 KXG51529.1 - 1.8e-05 24.7 2.4 0.18 11.9 0.1 4.1 3 1 1 4 4 4 2 Laminin Domain II TPR_8 PF13181.6 KXG51529.1 - 0.00013 21.9 0.1 1.2e+02 3.3 0.0 8.1 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXG51529.1 - 0.00023 21.7 24.3 16 6.2 0.0 9.8 9 3 1 10 10 10 0 Tetratricopeptide repeat VWA_2 PF13519.6 KXG51529.1 - 0.017 15.7 2.8 22 5.7 0.0 5.8 4 2 3 7 7 7 0 von Willebrand factor type A domain TOM20_plant PF06552.12 KXG51529.1 - 0.025 14.3 0.9 9 6.0 0.0 3.8 3 1 2 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 DUF4404 PF14357.6 KXG51529.1 - 2.7 8.7 16.3 5 7.8 1.3 5.5 6 1 1 7 7 6 0 Domain of unknown function (DUF4404) 3-alpha PF03475.14 KXG51529.1 - 3.7 7.5 6.4 13 5.8 0.1 4.7 5 0 0 5 5 5 0 3-alpha domain ocr PF08684.10 KXG51529.1 - 5.1 7.6 7.5 9.6 6.7 0.6 4.5 3 2 1 4 4 4 0 DNA mimic ocr Peptidase_C14 PF00656.22 KXG51530.1 - 2.2e-20 73.7 0.0 4.4e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 KXG51530.1 - 0.091 12.3 0.0 1.4 8.4 0.0 2.4 1 1 0 1 1 1 0 Peptidase C13 family adh_short PF00106.25 KXG51531.1 - 1.4e-28 99.7 0.2 2e-28 99.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG51531.1 - 2.8e-20 72.9 0.7 3.3e-20 72.6 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KXG51531.1 - 7.5e-09 35.7 0.3 1.1e-08 35.2 0.3 1.3 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KXG51531.1 - 2e-07 31.1 0.1 2.8e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXG51531.1 - 0.00012 21.6 0.1 0.00035 20.1 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG51531.1 - 0.0018 17.8 0.1 0.0056 16.1 0.1 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase HsbA PF12296.8 KXG51531.1 - 0.0032 17.9 0.4 0.016 15.6 0.1 2.1 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Sacchrp_dh_NADP PF03435.18 KXG51531.1 - 0.028 14.7 0.1 0.064 13.5 0.1 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain MFS_1 PF07690.16 KXG51533.1 - 2.2e-22 79.4 31.4 1.6e-11 43.8 1.2 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.8 KXG51533.1 - 6.2e-06 25.1 0.8 0.0012 17.6 0.4 2.4 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like DUF1772 PF08592.11 KXG51533.1 - 0.00023 21.5 11.3 0.13 12.6 0.0 4.4 3 2 1 4 4 4 2 Domain of unknown function (DUF1772) MFS_2 PF13347.6 KXG51533.1 - 0.00034 19.3 6.7 0.00034 19.3 6.7 3.4 4 0 0 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.7 KXG51533.1 - 0.0012 17.8 5.6 0.11 11.3 0.0 3.3 4 0 0 4 4 4 2 MFS_1 like family Trp_oprn_chp PF09534.10 KXG51533.1 - 0.016 15.0 1.6 0.041 13.7 0.8 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CENP-B_dimeris PF09026.10 KXG51533.1 - 0.02 15.2 2.4 0.052 13.9 2.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF485 PF04341.12 KXG51533.1 - 0.025 14.5 0.3 0.025 14.5 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF485 ATP-synt_I PF03899.15 KXG51533.1 - 0.031 14.6 0.2 0.031 14.6 0.2 3.9 4 0 0 4 4 4 0 ATP synthase I chain FAM176 PF14851.6 KXG51533.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 FAM176 family LacY_symp PF01306.19 KXG51533.1 - 0.11 11.3 9.2 0.06 12.1 0.5 3.0 3 0 0 3 3 3 0 LacY proton/sugar symporter Wzy_C PF04932.15 KXG51533.1 - 0.32 10.6 7.5 10 5.8 0.5 3.8 3 1 0 3 3 3 0 O-Antigen ligase zf-RING_2 PF13639.6 KXG51534.1 - 3.4e-08 33.7 3.4 3.4e-08 33.7 3.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KXG51534.1 - 2.2e-07 31.0 7.9 1.6e-06 28.3 7.9 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXG51534.1 - 2.9e-07 30.2 0.3 7e-07 29.0 0.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXG51534.1 - 2.5e-05 24.0 3.2 5.7e-05 22.9 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXG51534.1 - 6e-05 22.8 5.7 0.00016 21.5 1.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXG51534.1 - 6.4e-05 22.5 1.0 0.00013 21.5 1.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KXG51534.1 - 0.00015 21.7 2.6 0.00043 20.2 0.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXG51534.1 - 0.00033 20.6 3.4 0.0013 18.7 3.4 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXG51534.1 - 0.0039 17.2 2.0 0.061 13.4 0.8 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXG51534.1 - 0.0053 16.6 2.0 0.0053 16.6 2.0 1.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXG51534.1 - 0.035 14.3 1.1 0.069 13.3 1.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KXG51534.1 - 0.31 11.4 2.3 0.61 10.4 2.3 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_11 PF17123.5 KXG51534.1 - 1.1 9.1 4.6 0.49 10.2 0.3 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_4 PF14570.6 KXG51534.1 - 3 7.7 4.2 1.3 8.8 1.6 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF3431 PF11913.8 KXG51535.1 - 1.2e-88 296.5 0.0 1.5e-88 296.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Tim17 PF02466.19 KXG51537.1 - 2.6e-13 50.3 0.3 4.4e-13 49.6 0.3 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Brix PF04427.18 KXG51538.1 - 6.3e-33 114.5 0.0 9e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain NUP50 PF08911.11 KXG51538.1 - 1.4 9.7 5.9 7.5 7.3 5.8 2.4 1 1 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) Sugar_tr PF00083.24 KXG51539.1 - 1.2e-79 268.3 22.3 1.4e-79 268.1 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG51539.1 - 2.1e-22 79.5 5.4 2.1e-22 79.5 5.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily ABC_membrane PF00664.23 KXG51540.1 - 5e-85 285.5 42.9 1.1e-42 146.6 16.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXG51540.1 - 8.8e-66 220.6 0.0 5.9e-35 120.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXG51540.1 - 7.3e-13 48.5 1.8 0.0028 17.1 0.0 4.7 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXG51540.1 - 1.5e-08 35.0 0.2 0.0062 16.8 0.0 3.6 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KXG51540.1 - 1.8e-08 34.5 0.1 0.0068 16.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KXG51540.1 - 2.2e-08 33.7 0.6 0.0014 18.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KXG51540.1 - 4.9e-07 30.3 0.0 0.0032 17.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 KXG51540.1 - 1.3e-05 25.2 0.1 0.3 11.1 0.0 3.1 4 0 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 KXG51540.1 - 4.9e-05 23.2 0.0 0.33 10.6 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KXG51540.1 - 5.8e-05 23.7 0.0 0.35 11.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXG51540.1 - 6.3e-05 22.8 0.4 1.8 8.2 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 KXG51540.1 - 0.00036 21.0 1.4 0.26 11.7 0.2 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 KXG51540.1 - 0.00036 19.5 2.1 0.033 13.0 0.1 2.9 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_7 PF12775.7 KXG51540.1 - 0.00036 20.1 0.0 0.56 9.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_21 PF13304.6 KXG51540.1 - 0.0004 20.3 0.0 0.85 9.4 0.0 3.2 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KXG51540.1 - 0.00073 19.2 0.1 0.7 9.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KXG51540.1 - 0.0013 18.9 0.1 0.61 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KXG51540.1 - 0.0036 16.5 0.0 1 8.5 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain G-alpha PF00503.20 KXG51540.1 - 0.006 15.8 0.1 0.53 9.4 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit Zeta_toxin PF06414.12 KXG51540.1 - 0.0072 15.6 0.0 0.73 9.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 KXG51540.1 - 0.0074 16.4 0.2 2.5 8.2 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KXG51540.1 - 0.0075 16.5 0.2 0.5 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KXG51540.1 - 0.0081 16.3 0.2 0.7 9.9 0.1 2.5 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_24 PF13479.6 KXG51540.1 - 0.014 15.2 0.0 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXG51540.1 - 0.016 15.6 0.0 1.5 9.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 KXG51540.1 - 0.025 14.5 0.0 0.45 10.4 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_18 PF13238.6 KXG51540.1 - 0.026 15.1 0.1 2.2 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXG51540.1 - 0.048 13.6 0.5 16 5.4 0.0 2.9 3 0 0 3 3 3 0 NACHT domain IstB_IS21 PF01695.17 KXG51540.1 - 0.062 13.0 0.6 8.7 6.0 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein PRK PF00485.18 KXG51540.1 - 0.068 12.9 0.2 7.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TniB PF05621.11 KXG51540.1 - 0.074 12.4 0.3 13 5.1 0.0 3.3 4 0 0 4 4 3 0 Bacterial TniB protein APS_kinase PF01583.20 KXG51540.1 - 0.1 12.5 0.1 16 5.3 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase Ploopntkinase3 PF18751.1 KXG51540.1 - 0.1 12.5 0.0 6.9 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ATP_bind_1 PF03029.17 KXG51540.1 - 0.13 12.0 0.1 21 4.8 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SbcCD_C PF13558.6 KXG51540.1 - 0.16 12.3 6.5 2.5 8.4 0.1 3.8 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AMP-binding PF00501.28 KXG51541.1 - 1.8e-206 685.7 0.0 1.1e-73 248.2 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KXG51541.1 - 5e-179 595.8 0.0 9.6e-47 159.7 0.0 6.5 5 2 0 5 5 5 5 Condensation domain PP-binding PF00550.25 KXG51541.1 - 2.3e-41 140.0 0.1 9.5e-13 48.3 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXG51541.1 - 9.6e-06 26.5 0.0 2.7 9.0 0.0 3.8 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KXG51541.1 - 0.0078 14.9 0.0 1.4 7.5 0.0 3.1 3 0 0 3 3 3 2 Transferase family Fis1_TPR_N PF14852.6 KXG51541.1 - 0.22 11.2 0.5 16 5.3 0.0 2.8 3 0 0 3 3 3 0 Fis1 N-terminal tetratricopeptide repeat ADH_N PF08240.12 KXG51542.1 - 5.4e-29 100.3 4.7 1e-28 99.4 4.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG51542.1 - 7.3e-17 61.6 0.1 1.6e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXG51542.1 - 2.2e-06 27.3 0.1 3.4e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXG51542.1 - 9.4e-05 23.5 0.0 0.00021 22.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXG51542.1 - 0.6 9.4 3.9 0.33 10.2 1.5 1.8 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Aa_trans PF01490.18 KXG51543.1 - 2.2e-54 184.7 39.2 2.5e-54 184.6 39.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein His_Phos_2 PF00328.22 KXG51544.1 - 5.9e-39 134.5 0.0 7.8e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sugar_tr PF00083.24 KXG51545.1 - 4.8e-92 309.2 15.2 5.7e-92 308.9 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG51545.1 - 2.1e-32 112.4 28.6 8e-29 100.6 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG51545.1 - 0.00012 20.6 4.9 0.00014 20.4 0.5 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KXG51545.1 - 0.01 14.4 19.1 0.012 14.2 4.3 3.3 2 2 1 3 3 3 0 MFS/sugar transport protein OATP PF03137.20 KXG51545.1 - 0.068 11.4 4.4 0.057 11.7 0.9 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3792 PF12670.7 KXG51545.1 - 0.078 13.1 18.7 0.035 14.3 6.7 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) RUN PF02759.19 KXG51545.1 - 0.17 11.8 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 RUN domain Fungal_trans PF04082.18 KXG51546.1 - 1.6e-08 33.9 0.1 3.5e-08 32.8 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cupin_2 PF07883.11 KXG51547.1 - 3.9e-20 71.3 0.8 5.2e-10 38.9 0.3 2.2 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KXG51547.1 - 4.1e-19 68.0 1.5 7.7e-16 57.6 0.4 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KXG51547.1 - 2.5e-05 24.2 0.3 0.035 14.0 0.0 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 KXG51547.1 - 0.00014 22.0 0.0 0.00028 21.0 0.0 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_1 PF00190.22 KXG51547.1 - 0.02 14.5 0.1 0.6 9.7 0.0 2.4 2 1 0 2 2 2 0 Cupin F-box-like PF12937.7 KXG51548.1 - 0.013 15.3 0.1 0.03 14.2 0.1 1.7 1 0 0 1 1 1 0 F-box-like La_HTH_kDCL PF18177.1 KXG51548.1 - 0.12 12.7 0.3 0.32 11.3 0.0 1.9 2 0 0 2 2 2 0 La HTH in kinetoplastid DICER domain FAD_binding_4 PF01565.23 KXG51551.1 - 1e-23 83.6 1.2 1.8e-23 82.8 0.5 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXG51551.1 - 0.067 13.3 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Berberine and berberine like Viral_Beta_CD PF04530.12 KXG51552.1 - 0.12 12.7 0.3 0.43 10.9 0.3 1.9 1 0 0 1 1 1 0 Viral Beta C/D like family DUF373 PF04123.13 KXG51552.1 - 1.4 8.3 6.1 2 7.7 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Dynamin_N PF00350.23 KXG51553.1 - 1.8e-11 44.4 0.0 5.5e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KXG51553.1 - 2.9e-07 30.5 0.0 8.2e-06 25.9 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXG51553.1 - 7.5e-06 25.9 0.1 6.4e-05 22.9 0.0 2.4 2 1 0 2 2 2 1 RsgA GTPase Roc PF08477.13 KXG51553.1 - 0.0015 18.8 0.0 0.0041 17.3 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KXG51553.1 - 0.0022 18.4 0.0 0.0089 16.4 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KXG51553.1 - 0.0042 17.6 0.1 0.021 15.3 0.0 2.3 3 0 0 3 3 3 1 ABC transporter Septin PF00735.18 KXG51553.1 - 0.011 15.0 0.0 0.03 13.6 0.0 1.7 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 KXG51553.1 - 0.02 14.2 0.6 0.037 13.3 0.1 1.7 2 0 0 2 2 2 0 AIG1 family AAA_22 PF13401.6 KXG51553.1 - 0.021 15.1 0.1 0.34 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KXG51553.1 - 0.045 13.5 0.4 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain IIGP PF05049.13 KXG51553.1 - 0.1 11.7 0.0 0.34 9.9 0.0 1.9 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Guanylate_kin PF00625.21 KXG51553.1 - 0.24 11.1 1.0 0.62 9.7 0.0 2.3 3 0 0 3 3 3 0 Guanylate kinase MACPF PF01823.19 KXG51555.1 - 2.3e-13 50.7 1.5 4.8e-13 49.7 1.5 1.5 1 0 0 1 1 1 1 MAC/Perforin domain Fungal_trans PF04082.18 KXG51557.1 - 8.9e-12 44.6 0.8 1.7e-11 43.7 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Methyltransf_25 PF13649.6 KXG51558.1 - 6.9e-14 52.3 0.0 1.2e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG51558.1 - 6.9e-12 45.9 0.0 1.1e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG51558.1 - 1.5e-10 41.0 0.0 2.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG51558.1 - 2.1e-07 31.0 0.0 2.6e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG51558.1 - 5e-07 30.4 0.0 7.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG51558.1 - 0.00037 19.9 0.1 0.00051 19.4 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KXG51558.1 - 0.00037 20.0 0.8 0.00068 19.1 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXG51558.1 - 0.00043 19.9 0.1 0.00059 19.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KXG51558.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase N6_N4_Mtase PF01555.18 KXG51558.1 - 0.082 12.6 0.0 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 DNA methylase Response_reg PF00072.24 KXG51559.1 - 2.6e-18 66.2 0.0 6.2e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KXG51559.1 - 1.5e-17 64.1 0.0 4.5e-17 62.6 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lipase_GDSL_2 PF13472.6 KXG51559.1 - 3e-10 40.8 0.1 3.1e-09 37.5 0.0 2.5 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase family HisKA PF00512.25 KXG51559.1 - 4.4e-10 39.5 0.2 2.6e-09 37.0 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Lipase_GDSL PF00657.22 KXG51559.1 - 1.4e-06 28.4 0.0 4.5e-05 23.5 0.0 2.6 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase Glyco_transf_20 PF00982.21 KXG51560.1 - 1.8e-132 442.4 0.0 2.2e-132 442.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 KXG51560.1 - 7.2e-06 25.7 0.1 0.00011 21.7 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXG51560.1 - 0.00016 22.1 0.0 0.00057 20.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 B5 PF03484.15 KXG51560.1 - 0.037 14.3 0.3 0.072 13.4 0.3 1.5 1 1 0 1 1 1 0 tRNA synthetase B5 domain Glyco_trans_1_2 PF13524.6 KXG51560.1 - 0.039 14.4 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 DAO PF01266.24 KXG51561.1 - 1.2e-41 143.5 0.3 1.7e-41 143.0 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 KXG51561.1 - 4.9e-11 42.4 0.2 1.5e-10 40.8 0.1 1.9 2 0 0 2 2 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.6 KXG51561.1 - 1.8e-07 31.3 0.4 5.5e-07 29.7 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG51561.1 - 6.6e-06 25.6 0.7 1.6e-05 24.3 0.7 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXG51561.1 - 1.4e-05 24.7 0.3 0.0011 18.4 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXG51561.1 - 4e-05 23.0 0.0 7.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KXG51561.1 - 4.4e-05 22.9 0.0 7.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KXG51561.1 - 4.5e-05 22.7 0.1 8.7e-05 21.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXG51561.1 - 9.7e-05 21.8 0.1 0.00032 20.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXG51561.1 - 0.00057 19.0 0.6 0.0017 17.4 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 KXG51561.1 - 0.0018 17.5 0.4 0.01 14.9 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KXG51561.1 - 0.0022 18.5 0.2 0.0058 17.2 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXG51561.1 - 0.0023 17.3 0.9 0.02 14.2 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KXG51561.1 - 0.013 14.2 0.1 0.022 13.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Crystall_2 PF09076.10 KXG51561.1 - 0.024 14.5 0.0 0.066 13.1 0.0 1.7 1 0 0 1 1 1 0 Beta/Gamma crystallin 3HCDH_N PF02737.18 KXG51561.1 - 0.024 14.5 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KXG51561.1 - 0.039 13.9 0.6 0.28 11.1 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ferritin_2 PF13668.6 KXG51562.1 - 4.6e-44 149.9 1.7 4.6e-44 149.9 1.7 2.0 2 0 0 2 2 2 1 Ferritin-like domain DUF455 PF04305.14 KXG51562.1 - 0.076 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF455) TIG PF01833.24 KXG51562.1 - 0.11 12.5 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 IPT/TIG domain Zn_clus PF00172.18 KXG51563.1 - 6.9e-10 38.9 9.8 1.3e-09 38.1 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXG51563.1 - 3.3e-06 26.2 0.2 4.6e-06 25.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_20 PF14561.6 KXG51563.1 - 0.033 14.5 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat GMC_oxred_N PF00732.19 KXG51564.1 - 2.4e-55 188.0 0.0 3.1e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG51564.1 - 3.8e-30 105.3 0.0 7.8e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXG51564.1 - 6.6e-06 25.5 0.4 0.042 12.9 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KXG51564.1 - 7.7e-05 21.9 0.0 0.00016 20.9 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXG51564.1 - 0.00074 18.8 0.3 0.01 15.1 0.0 2.5 3 0 0 3 3 3 1 Thi4 family NAD_binding_8 PF13450.6 KXG51564.1 - 0.0058 16.8 0.3 0.015 15.5 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG51564.1 - 0.048 12.9 0.0 0.094 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXG51564.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KXG51564.1 - 0.18 11.0 0.5 7.9 5.6 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG51564.1 - 0.85 9.1 4.8 0.37 10.3 1.3 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF202 PF02656.15 KXG51565.1 - 1.1e-13 51.5 5.0 1.1e-13 51.5 5.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CoA_binding_3 PF13727.6 KXG51565.1 - 0.17 11.9 2.0 0.2 11.6 2.0 1.3 1 0 0 1 1 1 0 CoA-binding domain DUF5337 PF17272.2 KXG51565.1 - 2.6 7.9 8.4 0.79 9.6 4.5 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5337) HHH PF00633.23 KXG51567.1 - 0.004 17.0 0.1 0.0088 15.9 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Peptidase_S8 PF00082.22 KXG51569.1 - 1.1e-24 87.2 0.0 1.8e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Subtilase family LSPR PF06049.12 KXG51569.1 - 2.2 8.5 4.1 7.9 6.8 0.1 3.2 2 0 0 2 2 2 0 Coagulation Factor V LSPD Repeat Metallophos PF00149.28 KXG51570.1 - 1.2e-36 127.1 0.1 2.1e-36 126.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXG51570.1 - 4.7e-14 52.6 0.6 1e-13 51.4 0.6 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain zf-C2H2 PF00096.26 KXG51570.1 - 0.22 12.0 4.3 36 5.1 0.6 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type Glyco_hydro_76 PF03663.14 KXG51571.1 - 6.9e-108 361.4 19.0 7.9e-108 361.2 19.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXG51571.1 - 0.00045 19.4 5.1 0.0018 17.4 0.5 2.3 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 DUF918 PF06033.11 KXG51572.1 - 0.02 14.9 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) Aminotran_5 PF00266.19 KXG51574.1 - 3.1e-28 98.8 0.0 4e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 KXG51574.1 - 0.016 15.2 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain KR PF08659.10 KXG51574.1 - 0.041 13.8 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 KR domain DUF1471 PF07338.13 KXG51574.1 - 4.2 7.4 4.7 17 5.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1471) Metallophos_2 PF12850.7 KXG51575.1 - 6.9e-12 45.9 0.0 8.8e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.22 KXG51576.1 - 2.3e-15 56.1 0.5 4.2e-15 55.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spc7 PF08317.11 KXG51576.1 - 0.011 14.6 4.5 0.014 14.3 4.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Nup35_RRM_2 PF14605.6 KXG51576.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF3450 PF11932.8 KXG51576.1 - 0.015 14.6 3.1 0.02 14.2 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) COG6 PF06419.11 KXG51576.1 - 0.028 12.7 0.4 0.034 12.4 0.4 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 BLOC1_2 PF10046.9 KXG51576.1 - 0.028 14.7 1.9 0.044 14.1 1.9 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 KXG51576.1 - 0.054 14.0 0.4 0.098 13.1 0.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 KXG51576.1 - 0.097 12.5 3.4 0.13 12.1 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 KXG51576.1 - 0.16 9.8 0.4 0.19 9.6 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Troponin PF00992.20 KXG51576.1 - 0.16 12.2 6.2 0.24 11.7 6.2 1.2 1 0 0 1 1 1 0 Troponin APG6_N PF17675.1 KXG51576.1 - 0.26 11.8 8.6 0.36 11.4 8.6 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region EMP24_GP25L PF01105.24 KXG51576.1 - 0.31 11.0 0.8 0.42 10.5 0.8 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ZapB PF06005.12 KXG51576.1 - 0.47 10.9 6.5 0.83 10.1 6.5 1.3 1 0 0 1 1 1 0 Cell division protein ZapB OmpH PF03938.14 KXG51576.1 - 1 9.7 7.4 1.5 9.1 7.4 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 KXG51576.1 - 1.2 8.9 5.0 2 8.3 5.0 1.3 1 0 0 1 1 1 0 Septum formation initiator HECT PF00632.25 KXG51577.1 - 2.4e-96 322.8 0.0 3.2e-96 322.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KXG51577.1 - 2.4e-31 107.5 24.4 1.4e-12 47.4 3.1 4.7 5 0 0 5 5 5 3 WW domain C2 PF00168.30 KXG51577.1 - 5.7e-19 68.3 0.0 1.4e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain N2227 PF07942.12 KXG51579.1 - 5.9e-59 199.5 0.0 3.3e-58 197.0 0.0 1.9 2 0 0 2 2 2 1 N2227-like protein Methyltransf_23 PF13489.6 KXG51579.1 - 2.7e-05 24.1 0.0 7.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG51579.1 - 9.1e-05 23.0 0.0 0.00054 20.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG51579.1 - 0.00032 21.4 0.0 0.0014 19.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG51579.1 - 0.005 17.5 0.0 0.033 14.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG51579.1 - 0.022 14.6 0.0 0.098 12.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DUF3106 PF11304.8 KXG51579.1 - 0.21 12.1 2.7 0.26 11.8 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) GCS PF03074.16 KXG51580.1 - 6e-115 384.5 0.0 7.6e-115 384.2 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase MFS_1 PF07690.16 KXG51581.1 - 2.4e-28 99.1 37.4 3.9e-21 75.4 9.7 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG51581.1 - 7.5e-07 28.4 11.4 7.5e-07 28.4 11.4 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG51582.1 - 3.7e-25 88.6 34.9 3.7e-25 88.6 34.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Nucleoside_tran PF01733.18 KXG51582.1 - 0.01 15.2 1.3 0.01 15.2 1.3 1.7 2 0 0 2 2 2 0 Nucleoside transporter DAO PF01266.24 KXG51583.1 - 5.7e-31 108.4 0.1 6.4e-31 108.2 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXG51583.1 - 0.0022 17.3 0.4 0.005 16.1 0.4 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KXG51583.1 - 0.0051 17.4 1.0 0.02 15.4 1.0 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG51583.1 - 0.0075 15.4 0.0 0.016 14.3 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG51583.1 - 0.0096 15.2 0.0 0.021 14.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXG51583.1 - 0.025 14.2 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 KXG51583.1 - 0.033 14.4 0.3 0.033 14.4 0.3 2.0 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXG51583.1 - 0.049 12.9 0.3 0.095 11.9 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 KXG51583.1 - 0.051 14.0 0.3 0.092 13.2 0.3 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KXG51583.1 - 0.071 13.1 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KXG51583.1 - 0.14 12.4 0.9 0.32 11.3 0.9 1.6 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KXG51583.1 - 0.36 11.1 0.9 1 9.6 0.5 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sod_Ni PF09055.11 KXG51584.1 - 0.13 12.8 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 Nickel-containing superoxide dismutase Glyco_hydro_76 PF03663.14 KXG51585.1 - 2.9e-147 491.0 23.2 3.6e-147 490.7 23.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 SGL PF08450.12 KXG51586.1 - 2.6e-06 27.2 0.4 0.0045 16.6 0.1 3.0 1 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region NIF PF03031.18 KXG51587.1 - 3.8e-59 198.9 0.0 7.5e-59 198.0 0.0 1.5 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase IF-2B PF01008.17 KXG51588.1 - 2.3e-55 187.8 0.1 1.5e-53 181.8 0.1 2.1 1 1 0 1 1 1 1 Initiation factor 2 subunit family Ribosom_S12_S23 PF00164.25 KXG51589.1 - 1.6e-50 169.5 0.8 2e-50 169.2 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF5315 PF17242.2 KXG51590.1 - 1.4e-26 92.1 0.7 4.1e-26 90.6 0.7 1.8 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) AIM5 PF17050.5 KXG51591.1 - 8.9e-14 52.0 3.6 1.2e-13 51.6 3.6 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 Ribosomal_L17 PF01196.19 KXG51592.1 - 5.9e-30 104.0 0.5 4.1e-29 101.3 0.0 2.3 3 0 0 3 3 3 1 Ribosomal protein L17 Mg_chelatase_C PF13335.6 KXG51592.1 - 0.4 11.3 4.1 0.24 12.0 1.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal Glyco_hydro_18 PF00704.28 KXG51594.1 - 7.8e-50 170.4 0.1 1.2e-49 169.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KXG51594.1 - 1.6e-07 31.3 0.0 0.026 14.6 0.0 2.9 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KXG51594.1 - 8.7e-05 22.9 8.2 8.7e-05 22.9 8.2 3.5 4 1 0 4 4 4 1 Chitin recognition protein Hydantoinase_A PF01968.18 KXG51595.1 - 0.02 14.2 0.2 0.034 13.4 0.2 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Pkinase PF00069.25 KXG51596.1 - 0.0025 17.2 0.0 0.0053 16.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SUZ PF12752.7 KXG51597.1 - 4.9e-15 56.0 6.8 4.9e-15 56.0 6.8 3.9 3 1 0 3 3 3 1 SUZ domain R3H PF01424.22 KXG51597.1 - 1.9e-06 27.7 0.0 4.2e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 R3H domain cwf18 PF08315.12 KXG51599.1 - 3.8e-44 150.6 9.3 3.8e-44 150.6 9.3 1.4 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor PPR_2 PF13041.6 KXG51600.1 - 1e-11 44.8 4.0 5.2e-06 26.6 0.1 4.5 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.6 KXG51600.1 - 8.8e-08 32.1 0.3 0.0046 17.0 0.0 3.7 2 2 1 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 KXG51600.1 - 4.7e-06 26.5 0.0 0.22 11.9 0.0 3.7 3 0 0 3 3 3 2 PPR repeat PPR_1 PF12854.7 KXG51600.1 - 8.4e-05 22.2 0.0 0.024 14.3 0.0 3.0 3 0 0 3 3 3 2 PPR repeat TFIID-18kDa PF02269.16 KXG51601.1 - 1.1e-23 83.1 0.0 2e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KXG51601.1 - 0.00094 19.2 0.0 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 Bromodomain associated CENP-S PF15630.6 KXG51601.1 - 0.00096 19.5 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KXG51601.1 - 0.0038 17.6 0.0 0.0038 17.6 0.0 2.9 4 0 0 4 4 4 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 KXG51601.1 - 0.0045 17.5 0.0 0.0088 16.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KXG51601.1 - 0.014 15.7 0.1 0.048 14.0 0.1 1.9 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KXG51601.1 - 0.014 15.5 0.2 0.031 14.4 0.2 1.6 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KXG51601.1 - 0.027 14.6 0.1 0.05 13.8 0.1 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 KXG51601.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Tau95 PF09734.9 KXG51602.1 - 2.7e-22 80.1 0.0 3.9e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Fic PF02661.18 KXG51604.1 - 2.6e-11 44.2 0.0 4.8e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family MitMem_reg PF13012.6 KXG51605.1 - 3e-19 69.5 0.5 4.9e-19 68.8 0.5 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXG51605.1 - 3.2e-19 69.0 0.0 6.1e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 KXG51605.1 - 0.0014 18.7 0.0 0.0041 17.2 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) UTP25 PF06862.12 KXG51606.1 - 2.9e-191 636.4 0.0 3.5e-191 636.1 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KXG51606.1 - 0.00014 21.7 0.2 0.019 14.7 0.1 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase FoP_duplication PF13865.6 KXG51606.1 - 6.1 7.5 15.1 16 6.2 15.1 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 EamA PF00892.20 KXG51607.1 - 2.8e-20 72.9 32.3 8.1e-14 52.0 9.4 2.6 2 1 0 2 2 2 2 EamA-like transporter family DUF4728 PF15860.5 KXG51607.1 - 0.57 10.9 7.9 0.062 14.0 1.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4728) YhhN PF07947.14 KXG51608.1 - 1.3e-43 148.7 11.5 1.5e-43 148.5 11.5 1.0 1 0 0 1 1 1 1 YhhN family CTP_transf_like PF01467.26 KXG51609.1 - 7.8e-30 104.0 0.0 1.4e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1 PF05636.11 KXG51609.1 - 0.17 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase PP2C PF00481.21 KXG51610.1 - 1.5e-79 267.3 0.0 2.3e-79 266.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C He_PIG PF05345.12 KXG51611.1 - 4.2e-12 46.1 5.8 0.00026 21.1 0.1 4.2 4 0 0 4 4 4 3 Putative Ig domain SKG6 PF08693.10 KXG51611.1 - 1.2e-05 24.7 0.4 2.3e-05 23.7 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KXG51611.1 - 0.016 15.0 0.0 0.07 12.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Acetyltransf_1 PF00583.25 KXG51612.1 - 4e-10 39.9 0.0 4.9e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KXG51612.1 - 1.6e-07 31.2 0.0 2.4e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KXG51612.1 - 7.3e-06 26.3 0.1 9.7e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXG51612.1 - 1.3e-05 25.2 0.0 1.4e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KXG51612.1 - 0.00036 20.7 0.0 0.00048 20.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KXG51612.1 - 0.0027 17.5 0.2 0.0036 17.0 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 KXG51612.1 - 0.0045 17.1 0.1 0.0079 16.3 0.1 1.4 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KXG51612.1 - 0.023 14.8 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Metallophos PF00149.28 KXG51613.1 - 5.5e-06 27.0 0.1 8.1e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MOZART1 PF12554.8 KXG51615.1 - 2.7e-24 84.7 1.7 3.2e-24 84.4 1.7 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DUF1844 PF08899.11 KXG51615.1 - 0.0033 17.7 0.4 0.0049 17.1 0.2 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1844) WXG100 PF06013.12 KXG51615.1 - 0.026 14.7 0.2 0.54 10.5 0.1 2.0 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DHHA1 PF02272.19 KXG51615.1 - 0.098 13.1 0.1 0.11 12.9 0.1 1.1 1 0 0 1 1 1 0 DHHA1 domain CUE PF02845.16 KXG51616.1 - 3.6e-12 45.7 0.0 5.7e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 KXG51616.1 - 0.018 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain AFOR_C PF01314.18 KXG51616.1 - 0.03 13.3 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 HA2 PF04408.23 KXG51617.1 - 3.4e-17 62.7 0.0 6.9e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXG51617.1 - 5.4e-13 49.1 0.0 1.1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXG51617.1 - 4.3e-12 46.4 0.0 9.5e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXG51617.1 - 9.8e-07 29.1 0.0 2.1e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KXG51617.1 - 5.6e-06 26.2 0.1 1.1e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KXG51617.1 - 0.00013 21.8 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXG51617.1 - 0.00032 21.0 0.4 0.0016 18.8 0.0 2.2 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 KXG51617.1 - 0.0025 17.4 0.1 0.046 13.3 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 KXG51617.1 - 0.027 13.5 0.0 0.065 12.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Herpes_ori_bp PF02399.15 KXG51617.1 - 0.046 11.8 0.0 0.065 11.3 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein FBPase_2 PF06874.11 KXG51617.1 - 0.054 11.8 0.0 0.087 11.1 0.0 1.2 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase DUF2075 PF09848.9 KXG51617.1 - 0.088 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KXG51617.1 - 0.1 12.6 0.1 6.2 6.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXG51617.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXG51617.1 - 0.21 12.1 0.0 0.41 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PITH PF06201.13 KXG51618.1 - 4.9e-43 147.0 0.0 5.9e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain Snf7 PF03357.21 KXG51619.1 - 8.3e-36 123.2 2.5 1e-35 122.9 2.5 1.1 1 0 0 1 1 1 1 Snf7 MR_MLE_N PF02746.16 KXG51619.1 - 0.024 14.9 0.3 0.087 13.0 0.1 1.9 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain AAA PF00004.29 KXG51620.1 - 1.4e-89 297.3 0.0 1e-43 148.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXG51620.1 - 4.2e-23 80.9 1.0 3.6e-10 39.5 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KXG51620.1 - 9.4e-14 52.1 0.8 0.00012 22.5 0.1 4.5 2 2 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 KXG51620.1 - 1.2e-13 51.1 0.0 3e-06 27.1 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXG51620.1 - 1.7e-12 47.8 0.4 0.0024 18.1 0.0 5.3 3 2 0 4 4 3 2 AAA domain AAA_2 PF07724.14 KXG51620.1 - 1.3e-10 41.6 0.0 0.00016 21.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXG51620.1 - 2.2e-10 40.7 0.2 0.0019 18.2 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXG51620.1 - 4.6e-10 39.8 0.0 0.00016 21.8 0.0 3.0 3 1 0 3 3 2 2 AAA domain TIP49 PF06068.13 KXG51620.1 - 9.7e-09 34.9 0.0 0.00013 21.3 0.0 2.5 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 KXG51620.1 - 5.4e-08 32.9 0.0 0.0023 17.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KXG51620.1 - 8.9e-08 32.5 0.0 0.0065 16.8 0.0 2.8 2 1 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 KXG51620.1 - 9.6e-07 28.7 0.1 0.045 13.5 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KXG51620.1 - 1.8e-06 27.5 0.3 0.045 13.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXG51620.1 - 2.4e-06 27.4 0.0 0.0084 16.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXG51620.1 - 2.4e-06 28.1 0.0 0.057 14.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXG51620.1 - 2.6e-06 27.8 0.0 0.031 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KXG51620.1 - 4.6e-06 26.1 0.0 0.06 12.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin ATPase PF06745.13 KXG51620.1 - 1.5e-05 24.5 0.1 0.37 10.1 0.0 3.3 2 1 1 3 3 3 2 KaiC Rad17 PF03215.15 KXG51620.1 - 1.7e-05 24.8 0.0 0.085 12.8 0.0 2.6 2 1 0 2 2 2 2 Rad17 P-loop domain AAA_7 PF12775.7 KXG51620.1 - 2e-05 24.2 0.0 0.079 12.5 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region TsaE PF02367.17 KXG51620.1 - 2.9e-05 24.0 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KXG51620.1 - 4.2e-05 23.2 0.6 2.8 7.5 0.0 3.7 2 1 0 3 3 3 2 AAA domain AAA_17 PF13207.6 KXG51620.1 - 5.4e-05 23.6 0.4 0.19 12.2 0.3 3.3 2 1 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 KXG51620.1 - 5.5e-05 23.4 0.0 0.0083 16.3 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family NACHT PF05729.12 KXG51620.1 - 5.8e-05 23.1 0.1 1 9.3 0.0 3.5 3 1 1 4 4 3 2 NACHT domain ABC_tran PF00005.27 KXG51620.1 - 8.5e-05 23.1 0.0 0.35 11.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.26 KXG51620.1 - 0.00014 21.6 0.0 0.3 10.8 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain PhoH PF02562.16 KXG51620.1 - 0.00016 21.2 0.0 0.24 10.8 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.22 KXG51620.1 - 0.0008 18.7 0.0 0.98 8.5 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain Sigma54_activ_2 PF14532.6 KXG51620.1 - 0.00086 19.4 0.0 2 8.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain SKI PF01202.22 KXG51620.1 - 0.001 19.2 0.0 1.1 9.4 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase AAA_11 PF13086.6 KXG51620.1 - 0.0011 18.8 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KXG51620.1 - 0.0018 18.1 0.0 0.98 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 KXG51620.1 - 0.002 17.5 0.0 1.9 7.9 0.0 3.3 3 0 0 3 3 3 1 Bacterial TniB protein Parvo_NS1 PF01057.17 KXG51620.1 - 0.0023 17.1 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AFG1_ATPase PF03969.16 KXG51620.1 - 0.0023 16.9 0.2 0.7 8.7 0.0 2.8 3 0 0 3 3 3 1 AFG1-like ATPase ATPase_2 PF01637.18 KXG51620.1 - 0.0032 17.4 0.0 1.7 8.5 0.0 3.3 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KXG51620.1 - 0.0069 16.2 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 KXG51620.1 - 0.0072 15.5 0.0 0.083 12.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KXG51620.1 - 0.02 15.2 1.3 9.9 6.5 0.2 3.1 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KXG51620.1 - 0.021 14.1 0.0 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SRPRB PF09439.10 KXG51620.1 - 0.044 13.2 0.0 29 4.0 0.0 3.2 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit CPT PF07931.12 KXG51620.1 - 0.044 13.6 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 KXG51620.1 - 0.048 13.7 0.0 13 5.7 0.0 2.6 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit IPT PF01745.16 KXG51620.1 - 0.05 13.0 0.0 5.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase NTPase_1 PF03266.15 KXG51620.1 - 0.061 13.2 0.0 6.7 6.6 0.0 2.8 2 1 1 3 3 3 0 NTPase Bac_DnaA PF00308.18 KXG51620.1 - 0.13 12.1 0.0 4.3 7.1 0.0 3.0 3 1 0 3 3 3 0 Bacterial dnaA protein AAA_30 PF13604.6 KXG51620.1 - 0.18 11.5 0.1 29 4.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain BOP1NT PF08145.12 KXG51621.1 - 4.4e-108 361.1 7.5 6.6e-108 360.5 7.5 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KXG51621.1 - 4.8e-23 81.0 8.1 9e-10 39.0 0.2 5.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG51621.1 - 1.9e-06 28.1 0.0 0.0091 16.3 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Leo1 PF04004.13 KXG51623.1 - 9.8e-26 90.6 1.9 1.8e-25 89.7 0.0 2.3 2 1 0 2 2 2 1 Leo1-like protein Mob1_phocein PF03637.17 KXG51624.1 - 1.6e-50 171.4 0.0 7.2e-50 169.3 0.0 1.9 1 1 0 1 1 1 1 Mob1/phocein family NdhO PF11910.8 KXG51624.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Cyanobacterial and plant NDH-1 subunit O Shugoshin_N PF07558.11 KXG51625.1 - 0.0037 17.1 0.2 0.12 12.2 0.0 2.2 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Ub-Mut7C PF14451.6 KXG51625.1 - 0.05 13.5 0.3 0.42 10.5 0.3 2.1 1 1 0 1 1 1 0 Mut7-C ubiquitin UPF0242 PF06785.11 KXG51625.1 - 0.081 13.0 0.2 0.099 12.7 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 KXG51625.1 - 0.24 11.9 1.7 0.85 10.1 1.7 1.9 1 1 0 1 1 1 0 Cell division protein ZapB Rhomboid PF01694.22 KXG51626.1 - 3.2e-20 72.7 11.5 4.8e-20 72.1 10.5 1.7 2 0 0 2 2 2 1 Rhomboid family Ammonium_transp PF00909.21 KXG51627.1 - 0.47 9.1 4.1 0.68 8.6 4.1 1.1 1 0 0 1 1 1 0 Ammonium Transporter Family RVT_1 PF00078.27 KXG51628.1 - 7.6e-15 55.0 0.0 8.3e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PhoD PF09423.10 KXG51630.1 - 1.2e-09 37.7 2.9 8.3e-05 21.8 0.6 2.9 2 1 0 2 2 2 2 PhoD-like phosphatase AA_permease_2 PF13520.6 KXG51631.1 - 8.5e-44 150.0 50.5 1.1e-43 149.7 50.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG51631.1 - 2.9e-20 72.3 45.8 4.1e-20 71.8 45.8 1.1 1 0 0 1 1 1 1 Amino acid permease Kdo PF06293.14 KXG51632.1 - 0.00021 20.7 0.6 0.00072 19.0 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXG51632.1 - 0.0017 18.4 0.4 0.039 13.9 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG51632.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KXG51632.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 KXG51633.1 - 1.5e-11 44.2 0.0 2e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXG51633.1 - 0.00012 22.2 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KXG51633.1 - 0.0002 20.8 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXG51633.1 - 0.0036 16.7 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXG51633.1 - 0.0058 16.2 0.0 0.0094 15.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family DUF3336 PF11815.8 KXG51634.1 - 3.6e-38 130.4 0.0 3e-36 124.2 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3336) Patatin PF01734.22 KXG51634.1 - 2.7e-14 53.8 1.4 1.1e-13 51.8 0.1 2.2 2 1 0 2 2 2 1 Patatin-like phospholipase TAFH PF07531.14 KXG51634.1 - 0.043 13.9 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 NHR1 homology to TAF Ribosomal_L6 PF00347.23 KXG51635.1 - 7.6e-19 68.2 11.1 5.3e-09 36.6 1.1 3.3 3 0 0 3 3 3 2 Ribosomal protein L6 Glutaredoxin PF00462.24 KXG51635.1 - 7.7e-12 45.3 0.0 3e-11 43.4 0.0 2.1 1 0 0 1 1 1 1 Glutaredoxin Conotoxin PF02950.17 KXG51635.1 - 0.029 15.4 1.8 1 10.4 0.0 2.4 2 0 0 2 2 2 0 Conotoxin Presenilin PF01080.17 KXG51635.1 - 0.16 10.7 1.1 0.24 10.1 1.1 1.3 1 0 0 1 1 1 0 Presenilin CAF1 PF04857.20 KXG51635.1 - 0.19 10.8 2.3 0.28 10.3 2.3 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease BSP_II PF05432.11 KXG51635.1 - 1.1 8.8 12.0 1.7 8.3 12.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF4407 PF14362.6 KXG51635.1 - 2.1 7.6 5.5 3.3 7.0 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAND PF09110.11 KXG51635.1 - 3.2 8.5 12.0 33 5.3 7.3 2.3 2 0 0 2 2 2 0 HAND Connexin PF00029.19 KXG51635.1 - 3.5 7.3 5.0 27 4.4 0.1 2.1 2 0 0 2 2 2 0 Connexin U1snRNP70_N PF12220.8 KXG51635.1 - 3.9 8.2 9.9 49 4.6 7.4 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Hydrolase_4 PF12146.8 KXG51636.1 - 1.2e-08 34.5 0.0 4.1e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXG51636.1 - 3.8e-08 33.3 0.0 8.9e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Gryzun PF07919.12 KXG51637.1 - 6.7e-235 781.4 0.0 8.1e-235 781.1 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 KXG51637.1 - 9.1e-112 372.8 3.2 1.1e-100 336.5 5.1 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.7 KXG51637.1 - 0.065 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking RXT2_N PF08595.11 KXG51638.1 - 9.3e-42 142.7 0.0 9.3e-42 142.7 0.0 2.4 2 0 0 2 2 2 1 RXT2-like, N-terminal CDH-cyt PF16010.5 KXG51639.1 - 2e-68 229.7 2.3 2.5e-68 229.3 2.3 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase PEMT PF04191.13 KXG51640.1 - 1.3e-33 115.6 4.6 1.9e-33 115.0 2.4 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1223 PF06764.11 KXG51640.1 - 0.0024 18.0 0.1 0.0062 16.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1223) YrhK PF14145.6 KXG51640.1 - 0.37 10.7 8.9 0.048 13.5 2.8 2.6 2 1 0 2 2 2 0 YrhK-like protein ATP1G1_PLM_MAT8 PF02038.16 KXG51640.1 - 5.5 6.5 6.3 0.69 9.4 0.7 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family PXA PF02194.15 KXG51641.1 - 2.4e-51 174.3 0.3 2.4e-51 174.3 0.3 2.8 4 0 0 4 4 4 1 PXA domain Nexin_C PF08628.12 KXG51641.1 - 5.3e-26 91.4 0.0 6.8e-25 87.8 0.0 2.9 3 1 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 KXG51641.1 - 6.1e-22 77.7 0.2 1.3e-21 76.7 0.2 1.6 1 0 0 1 1 1 1 PX domain RGS PF00615.19 KXG51641.1 - 2.1e-10 40.9 0.0 6.9e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain RRP36 PF06102.12 KXG51641.1 - 0.69 9.9 7.0 0.53 10.2 0.7 2.5 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 F-box-like PF12937.7 KXG51642.1 - 0.034 14.0 0.8 0.063 13.2 0.2 1.7 2 0 0 2 2 2 0 F-box-like WD40 PF00400.32 KXG51644.1 - 1.3e-12 48.0 6.6 0.012 16.4 0.0 6.0 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG51644.1 - 0.00013 22.2 0.0 1.3 9.4 0.0 4.9 3 1 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXG51644.1 - 0.0025 17.2 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Ge1_WD40 PF16529.5 KXG51644.1 - 0.01 14.8 0.0 0.055 12.4 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FliO PF04347.13 KXG51644.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO tRNA-synt_1g PF09334.11 KXG51645.1 - 7.3e-147 489.2 0.0 9e-147 488.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KXG51645.1 - 6.2e-09 34.6 0.2 3.6e-05 22.2 0.0 3.7 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXG51645.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Elongin_A PF06881.11 KXG51645.1 - 0.91 10.1 4.3 0.85 10.2 2.4 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Yae1_N PF09811.9 KXG51646.1 - 2.4e-08 33.5 2.7 3.6e-08 33.0 2.7 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal UPF0160 PF03690.13 KXG51647.1 - 6.4e-127 423.6 0.0 7.3e-127 423.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ICE2 PF08426.10 KXG51648.1 - 4.3e-151 503.6 10.5 4.9e-151 503.5 10.5 1.0 1 0 0 1 1 1 1 ICE2 Endosulfine PF04667.17 KXG51649.1 - 7.7e-29 99.7 0.0 1.2e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.13 KXG51650.1 - 6e-83 277.3 0.0 6.7e-83 277.2 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase bPH_5 PF10882.8 KXG51650.1 - 0.00053 20.0 0.0 0.96 9.6 0.1 2.2 2 0 0 2 2 2 2 Bacterial PH domain Peptidase_S10 PF00450.22 KXG51651.1 - 7.7e-113 378.0 0.0 9.3e-113 377.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase WD40 PF00400.32 KXG51652.1 - 1.3e-28 98.6 21.0 5.4e-06 27.0 0.0 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG51652.1 - 5.2e-11 42.7 2.7 0.047 14.0 0.0 5.0 4 2 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KXG51652.1 - 0.063 12.3 0.3 1.4 7.9 0.1 2.1 2 0 0 2 2 2 0 Coatomer WD associated region Tcp11 PF05794.13 KXG51653.1 - 1e-111 374.2 0.0 1e-111 374.2 0.0 2.8 3 1 0 3 3 3 1 T-complex protein 11 LicD PF04991.13 KXG51653.1 - 0.035 14.2 0.7 0.074 13.2 0.7 1.5 1 0 0 1 1 1 0 LicD family IQ PF00612.27 KXG51653.1 - 6.2 6.9 5.9 0.46 10.4 0.4 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif HMA PF00403.26 KXG51655.1 - 3.6e-17 62.5 0.8 4.4e-17 62.3 0.8 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF211 PF02680.14 KXG51655.1 - 0.016 15.3 0.1 0.021 15.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Rrn6 PF10214.9 KXG51656.1 - 2.1e-169 565.8 0.8 8.7e-109 365.3 0.2 2.0 1 1 1 2 2 2 2 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.12 KXG51657.1 - 4e-22 78.2 0.0 9.3e-22 77.0 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Filament PF00038.21 KXG51657.1 - 0.00058 19.5 12.7 0.00093 18.9 12.7 1.2 1 0 0 1 1 1 1 Intermediate filament protein DUF4140 PF13600.6 KXG51657.1 - 0.72 10.3 5.3 1.7 9.2 5.3 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) WD40 PF00400.32 KXG51658.1 - 4.8e-20 71.5 13.1 6.9e-07 29.9 0.6 6.1 5 2 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG51658.1 - 6.2e-14 52.1 1.0 5.5e-05 23.4 0.5 4.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXG51658.1 - 2.4e-05 24.3 0.0 0.0098 15.8 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KXG51658.1 - 0.00029 19.5 0.2 0.51 8.8 0.0 2.5 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.8 KXG51658.1 - 0.00091 18.0 0.6 0.0083 14.8 0.1 2.2 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Hira PF07569.11 KXG51658.1 - 0.034 13.9 0.1 3 7.5 0.0 2.5 2 1 1 3 3 3 0 TUP1-like enhancer of split WD40_like PF17005.5 KXG51658.1 - 0.048 13.0 0.0 4.2 6.6 0.0 2.9 2 1 1 4 4 4 0 WD40-like domain Ge1_WD40 PF16529.5 KXG51658.1 - 0.095 11.6 0.7 23 3.8 0.0 3.3 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXG51658.1 - 0.12 12.4 3.3 13 5.9 0.0 3.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF5111 PF17138.4 KXG51658.1 - 0.12 12.2 0.8 1.5 8.7 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5111) Ribosomal_L32p PF01783.23 KXG51659.1 - 1.4e-13 50.8 5.5 1.9e-13 50.5 5.5 1.1 1 0 0 1 1 1 1 Ribosomal L32p protein family zinc-ribbons_6 PF07191.12 KXG51659.1 - 0.079 13.0 0.5 0.12 12.4 0.5 1.3 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.7 KXG51659.1 - 0.098 12.7 1.1 0.65 10.1 1.4 1.8 1 1 1 2 2 2 0 Double zinc ribbon Septin PF00735.18 KXG51660.1 - 3.4e-114 380.9 0.7 4e-114 380.6 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KXG51660.1 - 2.1e-08 34.2 0.0 5.3e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KXG51660.1 - 1.5e-05 24.5 0.0 2.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KXG51660.1 - 6e-05 23.0 0.4 0.00053 19.9 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KXG51660.1 - 7.1e-05 22.4 0.7 0.015 14.9 0.1 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KXG51660.1 - 0.00027 21.0 0.4 0.99 9.4 0.1 2.7 1 1 1 2 2 2 2 Dynamin family AAA_7 PF12775.7 KXG51660.1 - 0.0028 17.2 0.1 0.02 14.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 KXG51660.1 - 0.0054 15.9 0.1 0.0096 15.1 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KXG51660.1 - 0.0058 17.0 0.0 0.014 15.8 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 KXG51660.1 - 0.0082 15.5 0.3 0.11 11.9 0.3 2.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 KXG51660.1 - 0.0092 16.5 0.5 0.016 15.8 0.4 1.7 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KXG51660.1 - 0.012 15.9 0.1 0.027 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 KXG51660.1 - 0.056 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KXG51660.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 KXG51660.1 - 0.071 12.3 1.1 0.26 10.4 1.1 2.0 1 1 0 1 1 1 0 G-protein alpha subunit AAA_23 PF13476.6 KXG51660.1 - 0.15 12.5 0.7 0.36 11.3 0.7 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXG51660.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.21 KXG51661.1 - 5.2e-64 215.3 0.0 5.2e-64 215.3 0.0 2.6 4 0 0 4 4 3 1 Guanylate kinase GRAB PF10375.9 KXG51661.1 - 1.5e-08 34.2 0.1 3.3e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain AAA_18 PF13238.6 KXG51661.1 - 4.6e-05 24.0 7.1 0.00017 22.2 0.0 3.9 3 1 0 3 3 3 1 AAA domain Phage_GP20 PF06810.11 KXG51661.1 - 5.5e-05 23.0 7.2 5.5e-05 23.0 7.2 4.1 3 1 2 5 5 4 2 Phage minor structural protein GP20 AAA_16 PF13191.6 KXG51661.1 - 0.00018 21.9 0.1 0.00018 21.9 0.1 4.0 2 2 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.6 KXG51661.1 - 0.00098 19.3 2.7 0.0042 17.3 0.1 3.2 2 2 1 3 3 2 1 AAA domain AAA_22 PF13401.6 KXG51661.1 - 0.0012 19.2 6.7 0.0016 18.7 0.0 3.2 2 1 1 3 3 3 1 AAA domain ABC_tran PF00005.27 KXG51661.1 - 0.0019 18.7 0.0 0.0019 18.7 0.0 4.0 2 2 1 3 3 2 1 ABC transporter Rad17 PF03215.15 KXG51661.1 - 0.0022 18.0 0.2 0.095 12.6 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_29 PF13555.6 KXG51661.1 - 0.0026 17.5 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 KXG51661.1 - 0.003 16.6 0.1 0.015 14.4 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein Golgin_A5 PF09787.9 KXG51661.1 - 0.0038 16.7 15.9 0.0038 16.7 15.9 3.7 2 1 2 4 4 4 2 Golgin subfamily A member 5 RNA_helicase PF00910.22 KXG51661.1 - 0.0045 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 KXG51661.1 - 0.0064 16.8 0.0 0.0064 16.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain BST2 PF16716.5 KXG51661.1 - 0.012 16.2 46.5 0.39 11.3 8.7 6.3 3 2 2 6 6 6 0 Bone marrow stromal antigen 2 MMR_HSR1 PF01926.23 KXG51661.1 - 0.016 15.3 0.0 0.066 13.3 0.0 2.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 KXG51661.1 - 0.022 14.7 0.0 0.098 12.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 KXG51661.1 - 0.022 14.7 0.0 0.022 14.7 0.0 2.5 3 1 0 3 3 2 0 RsgA GTPase NTPase_1 PF03266.15 KXG51661.1 - 0.029 14.3 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 KXG51661.1 - 0.029 14.1 0.6 0.23 11.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KXG51661.1 - 0.059 13.4 2.3 0.091 12.8 0.0 2.6 3 0 0 3 3 1 0 AAA domain AAA_7 PF12775.7 KXG51661.1 - 0.069 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Spc7 PF08317.11 KXG51661.1 - 0.1 11.5 58.3 0.033 13.1 32.2 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KXG51661.1 - 0.15 12.1 17.2 1.2 9.1 5.0 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA PF00004.29 KXG51661.1 - 0.43 11.0 0.0 0.43 11.0 0.0 2.9 3 1 1 4 4 3 0 ATPase family associated with various cellular activities (AAA) Fib_alpha PF08702.10 KXG51661.1 - 0.6 10.3 31.5 0.36 11.0 1.6 4.2 2 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Filament PF00038.21 KXG51661.1 - 4.3 6.8 55.7 0.2 11.2 16.7 3.7 2 1 2 4 4 4 0 Intermediate filament protein DUF3584 PF12128.8 KXG51661.1 - 5.8 4.3 49.4 0.36 8.3 43.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Aa_trans PF01490.18 KXG51663.1 - 1e-36 126.5 31.4 1.4e-36 126.1 31.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DAO PF01266.24 KXG51664.1 - 1.4e-49 169.6 0.0 2e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KXG51664.1 - 1.4e-42 144.6 0.0 2.8e-42 143.6 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KXG51664.1 - 1.5e-07 30.8 0.8 5e-07 29.2 0.8 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG51664.1 - 0.00068 18.9 0.1 0.0019 17.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG51664.1 - 0.0013 18.9 0.1 0.0058 16.8 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXG51664.1 - 0.0014 18.1 0.6 0.0044 16.4 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KXG51664.1 - 0.0047 16.8 0.2 0.0089 15.9 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KXG51664.1 - 0.016 14.4 0.1 0.034 13.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KXG51664.1 - 0.019 14.3 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXG51664.1 - 0.036 12.8 0.5 0.058 12.1 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KXG51664.1 - 0.063 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KXG51664.1 - 0.11 13.1 0.2 0.33 11.5 0.2 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 KXG51664.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDI PF00996.18 KXG51664.1 - 0.17 10.4 0.1 3.4 6.1 0.0 2.0 2 0 0 2 2 2 0 GDP dissociation inhibitor p450 PF00067.22 KXG51665.1 - 7.5e-70 235.9 0.0 8.6e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Shugoshin_N PF07558.11 KXG51666.1 - 8.7e-19 67.1 5.0 2.1e-18 65.9 5.0 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KXG51666.1 - 6.5e-11 41.8 5.5 6.5e-11 41.8 5.5 2.6 3 0 0 3 3 3 1 Shugoshin C terminus bZIP_2 PF07716.15 KXG51666.1 - 0.019 15.0 0.3 0.079 13.1 0.3 2.1 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 KXG51666.1 - 0.033 14.3 1.3 0.2 11.8 1.3 2.4 1 0 0 1 1 1 0 bZIP transcription factor CRM1_C PF08767.11 KXG51667.1 - 1e-136 455.3 7.0 1e-136 455.3 7.0 2.9 2 1 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 KXG51667.1 - 7.9e-43 146.1 4.5 7.9e-43 146.1 4.5 4.0 5 0 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KXG51667.1 - 2.5e-33 113.5 4.8 1.1e-32 111.5 4.7 2.3 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KXG51667.1 - 9.4e-29 99.3 0.6 9.4e-29 99.3 0.6 2.8 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KXG51667.1 - 9.8e-20 69.8 0.9 2.3e-19 68.6 0.9 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KXG51667.1 - 1e-11 44.6 0.1 5.5e-11 42.2 0.1 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KXG51667.1 - 0.0022 17.9 1.4 0.11 12.5 0.0 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) Hemocyanin_M PF00372.19 KXG51667.1 - 0.061 12.5 0.3 0.21 10.7 0.1 2.0 2 0 0 2 2 2 0 Hemocyanin, copper containing domain DRE2_N PF16803.5 KXG51667.1 - 0.13 12.5 0.5 0.83 9.9 0.0 2.7 3 0 0 3 3 3 0 Fe-S cluster assembly protein DRE2 N-terminus Pre-PUA PF17832.1 KXG51667.1 - 0.15 12.8 0.1 6.9 7.4 0.0 3.5 3 0 0 3 3 3 0 Pre-PUA-like domain HD_assoc PF13286.6 KXG51667.1 - 1.1 9.8 3.1 22 5.7 0.1 3.9 4 0 0 4 4 3 0 Phosphohydrolase-associated domain Mac_assoc PF16628.5 KXG51668.1 - 1.2e-76 257.1 10.2 1.2e-76 257.1 10.2 1.9 2 1 1 3 3 3 1 Unstructured region on maltose acetyltransferase Mac PF12464.8 KXG51668.1 - 6.5e-12 45.5 0.0 1.9e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.18 KXG51668.1 - 2e-09 37.4 8.2 3.6e-09 36.6 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep PF00132.24 KXG51668.1 - 5.2e-09 35.5 8.3 0.0001 21.9 0.3 3.5 2 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXG51668.1 - 1.2e-05 25.0 9.4 3.4e-05 23.5 1.5 3.8 3 1 1 4 4 4 1 Hexapeptide repeat of succinyl-transferase ALAD PF00490.21 KXG51669.1 - 2.2e-116 388.4 0.0 2.5e-116 388.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DUF3752 PF12572.8 KXG51670.1 - 5.7e-38 130.8 10.8 1.2e-37 129.7 10.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Peptidase_M75 PF09375.10 KXG51671.1 - 0.18 11.2 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Imelysin A_deaminase PF00962.22 KXG51672.1 - 2.5e-122 408.3 0.0 3.4e-122 407.9 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Dynamin_M PF01031.20 KXG51673.1 - 2.6e-110 368.1 0.0 3.8e-110 367.6 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KXG51673.1 - 4.9e-54 182.9 0.0 9.4e-54 182.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KXG51673.1 - 3.4e-31 107.3 1.1 3.4e-31 107.3 1.1 1.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain SH3_1 PF00018.28 KXG51673.1 - 5.3e-24 83.6 6.1 2.9e-12 46.0 0.7 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KXG51673.1 - 5.8e-24 83.7 6.0 9.9e-12 44.5 0.7 2.4 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 KXG51673.1 - 4.8e-15 55.4 0.0 9.3e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 KXG51673.1 - 8.6e-14 51.0 0.8 4.7e-06 26.2 0.1 3.0 3 0 0 3 3 3 2 Variant SH3 domain MMR_HSR1 PF01926.23 KXG51673.1 - 0.00097 19.2 0.2 0.0058 16.7 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXG51673.1 - 0.13 11.7 0.1 4.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B UAA PF08449.11 KXG51674.1 - 1.1e-87 294.1 10.7 1.7e-87 293.4 10.7 1.2 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KXG51674.1 - 5.2e-05 22.6 0.5 5.2e-05 22.6 0.5 1.8 2 0 0 2 2 2 1 Nucleotide-sugar transporter SLC35F PF06027.12 KXG51674.1 - 0.45 10.0 8.4 1.4 8.3 1.5 2.3 2 0 0 2 2 2 0 Solute carrier family 35 EamA PF00892.20 KXG51674.1 - 0.83 9.8 27.4 0.93 9.7 7.6 3.6 2 2 0 2 2 2 0 EamA-like transporter family ELMO_CED12 PF04727.13 KXG51675.1 - 1.2e-47 162.3 0.0 2e-47 161.5 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KXG51675.1 - 3.5e-30 105.3 0.0 1.2e-29 103.6 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Rad17 PF03215.15 KXG51675.1 - 2.1e-26 93.0 0.0 4.1e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain DUF3361 PF11841.8 KXG51675.1 - 6.5e-15 55.4 0.0 1.4e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) AAA_16 PF13191.6 KXG51675.1 - 5.7e-05 23.6 0.0 0.00018 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KXG51675.1 - 0.0011 19.5 0.0 0.0025 18.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXG51675.1 - 0.014 15.7 0.0 0.039 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXG51675.1 - 0.027 14.2 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXG51675.1 - 0.053 14.1 0.0 0.23 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KXG51675.1 - 0.061 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1752 PF08550.10 KXG51676.1 - 5.8e-12 45.2 5.6 1.1e-11 44.3 5.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SUI1 PF01253.22 KXG51677.1 - 6e-23 81.2 0.3 1.1e-22 80.3 0.3 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.6 KXG51677.1 - 0.021 14.8 0.1 0.033 14.2 0.1 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Cgr1 PF03879.14 KXG51678.1 - 7.2e-32 110.0 25.4 7.2e-32 110.0 25.4 3.1 3 1 1 4 4 4 1 Cgr1 family GAS PF13851.6 KXG51678.1 - 0.0041 16.5 3.4 0.0041 16.5 3.4 2.4 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 KXG51678.1 - 0.013 15.5 1.1 0.22 11.5 1.1 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HrpB1_HrpK PF09613.10 KXG51678.1 - 0.097 12.3 0.2 0.25 11.0 0.1 1.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) MCU PF04678.13 KXG51678.1 - 0.13 12.3 0.2 0.13 12.3 0.2 2.5 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Exonuc_VII_L PF02601.15 KXG51678.1 - 0.25 10.8 12.2 0.23 11.0 0.0 2.5 3 0 0 3 3 3 0 Exonuclease VII, large subunit DUF2207 PF09972.9 KXG51678.1 - 0.4 9.4 0.0 0.4 9.4 0.0 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) APC_N_CC PF16689.5 KXG51678.1 - 0.79 9.8 5.3 2.4 8.3 0.4 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain T3SSipB PF16535.5 KXG51678.1 - 0.85 10.1 7.9 0.15 12.5 0.8 2.4 2 0 0 2 2 2 0 Type III cell invasion protein SipB Allexi_40kDa PF05549.11 KXG51678.1 - 1.2 8.5 5.2 5.7 6.4 0.2 2.4 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF16 PF01519.16 KXG51678.1 - 1.5 9.3 11.4 3 8.4 1.4 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 EMP24_GP25L PF01105.24 KXG51678.1 - 2 8.3 7.1 0.36 10.7 0.2 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD CENP-F_leu_zip PF10473.9 KXG51678.1 - 4.1 7.4 24.7 0.15 12.1 3.3 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mito_carr PF00153.27 KXG51679.1 - 4.3e-66 218.9 0.6 1e-20 73.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C12 PF01088.21 KXG51680.1 - 1.4e-26 93.5 0.0 1.9e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 NmrA PF05368.13 KXG51680.1 - 5.9e-12 45.7 0.0 9.6e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG51680.1 - 4.8e-05 23.3 0.0 6.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXG51680.1 - 0.059 13.6 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXG51680.1 - 0.068 12.6 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FlaF PF07309.11 KXG51680.1 - 0.13 12.3 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Flagellar protein FlaF dCMP_cyt_deam_1 PF00383.23 KXG51681.1 - 3.3e-14 52.6 0.1 3.9e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KXG51681.1 - 5.2e-09 36.4 1.4 3.1e-07 30.6 0.3 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KXG51681.1 - 4.1e-05 23.3 0.5 0.19 11.3 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Sortilin-Vps10 PF15902.5 KXG51682.1 - 2.9e-276 916.3 3.5 1.3e-141 472.5 1.1 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KXG51682.1 - 1.9e-92 308.2 6.9 1.1e-46 159.2 0.7 2.5 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KXG51682.1 - 2e-07 30.0 31.5 3.7 7.9 0.3 10.3 11 0 0 11 11 11 5 BNR/Asp-box repeat BNR_2 PF13088.6 KXG51682.1 - 0.033 13.5 0.9 59 2.8 0.0 4.9 5 1 0 6 6 6 0 BNR repeat-like domain Endonuc-HincII PF09226.11 KXG51682.1 - 0.05 12.9 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease HincII CHB_HEX_C PF03174.13 KXG51682.1 - 0.08 12.9 0.7 28 4.8 0.1 3.9 4 0 0 4 4 4 0 Chitobiase/beta-hexosaminidase C-terminal domain Mo-co_dimer PF03404.16 KXG51682.1 - 0.17 11.9 0.8 70 3.4 0.0 4.1 4 0 0 4 4 4 0 Mo-co oxidoreductase dimerisation domain Glyco_tranf_2_3 PF13641.6 KXG51683.1 - 7.2e-23 81.7 0.0 1.1e-22 81.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KXG51683.1 - 3e-10 40.3 0.3 3e-10 40.3 0.3 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KXG51683.1 - 0.012 15.4 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KXG51683.1 - 0.022 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 Sec10 PF07393.11 KXG51684.1 - 3.3e-229 763.0 0.0 3.9e-229 762.7 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Tropomyosin PF00261.20 KXG51684.1 - 0.042 13.2 0.1 0.13 11.6 0.1 1.8 1 0 0 1 1 1 0 Tropomyosin 60KD_IMP PF02096.20 KXG51684.1 - 0.061 13.2 0.0 9.6 6.1 0.0 2.4 2 0 0 2 2 2 0 60Kd inner membrane protein Phage_min_cap2 PF06152.11 KXG51684.1 - 0.13 11.1 0.2 11 4.7 0.1 2.3 2 0 0 2 2 2 0 Phage minor capsid protein 2 Baculo_PEP_C PF04513.12 KXG51684.1 - 0.66 10.0 3.9 9.1 6.3 0.2 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DHquinase_I PF01487.15 KXG51686.1 - 8.7e-35 121.0 0.0 1.5e-34 120.3 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KXG51686.1 - 1.7e-18 67.2 0.6 9.1e-18 64.9 0.0 2.3 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.11 KXG51686.1 - 1.5e-13 50.7 0.0 3.6e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 KXG51686.1 - 1.2e-08 35.1 0.0 2.6e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 KXG51686.1 - 1.5e-05 24.6 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain F420_oxidored PF03807.17 KXG51686.1 - 0.0099 16.4 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.18 KXG51687.1 - 1.2e-20 73.6 0.0 8.2e-20 70.9 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG51687.1 - 4.2e-07 30.0 13.7 6.7e-07 29.3 13.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXG51688.1 - 8.9e-17 61.0 56.7 1.6e-09 37.2 27.0 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG51688.1 - 2e-05 23.3 19.1 3.2e-05 22.6 19.1 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.25 KXG51689.1 - 2e-46 158.5 0.0 3.4e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TPR_12 PF13424.6 KXG51689.1 - 1.9e-44 149.8 28.4 2.1e-15 56.8 2.1 3.5 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KXG51689.1 - 2.1e-37 125.9 13.3 3.1e-10 39.6 0.0 4.6 4 1 0 4 4 4 4 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 KXG51689.1 - 1.9e-27 96.2 0.0 2.7e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ANAPC3 PF12895.7 KXG51689.1 - 1.9e-17 63.2 9.1 0.0013 19.0 0.0 4.3 1 1 3 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KXG51689.1 - 2.1e-16 58.6 10.1 0.0011 18.9 0.2 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXG51689.1 - 1.3e-13 50.2 6.7 0.0024 17.6 0.2 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 KXG51689.1 - 1.5e-07 31.9 6.4 0.38 11.4 0.1 4.3 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXG51689.1 - 2.2e-07 30.5 5.3 0.72 10.2 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXG51689.1 - 3.4e-07 30.5 3.4 3.4 8.7 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXG51689.1 - 4.4e-06 27.0 8.6 3.3 8.5 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_3 PF07720.12 KXG51689.1 - 1.6e-05 24.7 6.8 0.52 10.4 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXG51689.1 - 0.0007 20.0 0.0 0.54 11.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXG51689.1 - 0.001 19.5 6.2 0.19 12.3 0.2 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat SPO22 PF08631.10 KXG51689.1 - 0.0014 18.2 1.6 2.3 7.6 0.1 3.2 2 1 1 3 3 3 2 Meiosis protein SPO22/ZIP4 like Kdo PF06293.14 KXG51689.1 - 0.0018 17.6 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fis1_TPR_C PF14853.6 KXG51689.1 - 0.0019 18.2 6.0 3.3 7.8 0.5 4.3 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 KXG51689.1 - 0.014 15.4 8.7 3.3 8.0 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Haspin_kinase PF12330.8 KXG51689.1 - 0.092 11.7 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain TPR_17 PF13431.6 KXG51689.1 - 1.1 9.8 5.0 26 5.5 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Atu4866 PF11512.8 KXG51689.1 - 1.8 9.0 6.0 36 4.8 0.1 3.7 2 1 1 3 3 3 0 Agrobacterium tumefaciens protein Atu4866 TPR_11 PF13414.6 KXG51689.1 - 4.4 7.1 8.4 22 4.8 0.5 3.8 4 0 0 4 4 4 0 TPR repeat LysR_substrate PF03466.20 KXG51690.1 - 0.08 12.3 0.4 0.8 9.0 0.1 2.3 2 0 0 2 2 2 0 LysR substrate binding domain DUF3231 PF11553.8 KXG51691.1 - 0.0021 17.7 1.6 4.8 6.8 0.0 3.7 1 1 4 5 5 5 5 Protein of unknown function (DUF3231) FAM47 PF14642.6 KXG51691.1 - 0.0027 17.3 9.6 0.079 12.5 0.8 2.1 1 1 1 2 2 2 2 FAM47 family DUF2235 PF09994.9 KXG51692.1 - 1.9e-82 276.8 0.0 2.4e-82 276.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) RGI_lyase PF18370.1 KXG51692.1 - 0.13 12.6 0.4 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 Rhamnogalacturonan I lyases beta-sheet domain Fringe PF02434.16 KXG51693.1 - 7.2e-06 25.6 0.7 0.00073 19.1 0.2 3.0 2 1 0 2 2 2 1 Fringe-like PAN_1 PF00024.26 KXG51693.1 - 0.00016 21.5 0.1 0.00033 20.6 0.1 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 KXG51693.1 - 0.014 15.3 0.2 0.031 14.2 0.2 1.5 1 0 0 1 1 1 0 PAN domain Galactosyl_T PF01762.21 KXG51693.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Galactosyltransferase Glyco_transf_34 PF05637.12 KXG51693.1 - 0.38 10.4 2.3 0.65 9.7 2.3 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family MFS_1 PF07690.16 KXG51694.1 - 1.6e-20 73.4 40.8 1.6e-20 73.4 40.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_2 PF00891.18 KXG51695.1 - 3.4e-09 36.3 0.0 6e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KXG51695.1 - 0.16 12.0 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Glyco_transf_8 PF01501.20 KXG51697.1 - 0.031 13.8 0.1 0.031 13.8 0.1 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KXG51697.1 - 0.04 13.3 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Tox-REase-5 PF15648.6 KXG51697.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 5 DUF1115 PF06544.12 KXG51698.1 - 0.025 14.6 0.1 0.05 13.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1115) ABC2_membrane PF01061.24 KXG51699.1 - 8.2e-71 237.7 53.3 2e-37 128.7 26.7 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KXG51699.1 - 8.1e-37 126.8 0.0 3e-17 63.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXG51699.1 - 1.3e-23 82.7 0.2 1.3e-23 82.7 0.2 3.9 4 0 0 4 4 3 2 CDR ABC transporter AAA_16 PF13191.6 KXG51699.1 - 2.4e-07 31.3 0.2 3.8e-05 24.1 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 KXG51699.1 - 1e-05 24.8 35.5 0.00049 19.3 14.7 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KXG51699.1 - 4.3e-05 23.5 0.1 0.038 13.8 0.0 2.7 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXG51699.1 - 4.5e-05 23.4 0.1 0.0037 17.2 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KXG51699.1 - 8.3e-05 22.2 1.1 0.0076 16.0 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXG51699.1 - 8.9e-05 22.6 0.0 0.03 14.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 KXG51699.1 - 0.0005 19.7 0.2 0.037 13.6 0.1 2.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KXG51699.1 - 0.00065 20.0 0.2 0.16 12.2 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 KXG51699.1 - 0.0053 16.5 0.4 1.3 8.7 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXG51699.1 - 0.0061 17.1 0.1 0.043 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXG51699.1 - 0.0066 16.6 0.0 0.32 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KXG51699.1 - 0.031 14.8 0.1 0.074 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KXG51699.1 - 0.045 13.1 0.1 12 5.1 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.6 KXG51699.1 - 0.069 13.4 0.4 0.18 12.0 0.4 1.7 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 KXG51699.1 - 0.11 11.8 21.8 0.063 12.6 9.5 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein SMC_N PF02463.19 KXG51699.1 - 0.15 11.5 0.0 13 5.1 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KXG51699.1 - 0.15 11.9 0.1 5.8 6.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 KXG51699.1 - 0.26 11.2 0.4 1.6 8.6 0.1 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 KXG51699.1 - 0.42 9.9 1.1 4.9 6.4 0.3 2.6 3 0 0 3 3 3 0 Zeta toxin Fer2_2 PF01799.20 KXG51699.1 - 0.99 9.5 2.8 4.9 7.2 0.0 2.6 2 0 0 2 2 2 0 [2Fe-2S] binding domain Fungal_trans PF04082.18 KXG51700.1 - 9.8e-19 67.4 0.1 1.7e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyridoxal_deC PF00282.19 KXG51701.1 - 2e-72 244.0 0.0 2.5e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain GST_C_6 PF17171.4 KXG51701.1 - 0.14 12.0 0.0 0.93 9.3 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_28 PF00295.17 KXG51702.1 - 1.2e-55 188.9 6.8 1.6e-55 188.4 6.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 MAPEG PF01124.18 KXG51702.1 - 0.00099 19.0 0.1 0.002 18.1 0.1 1.4 1 0 0 1 1 1 1 MAPEG family DUF4528 PF15031.6 KXG51702.1 - 0.022 14.8 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) PS-DH PF14765.6 KXG51703.1 - 0.22 10.7 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 Polyketide synthase dehydratase MFS_1 PF07690.16 KXG51704.1 - 5.5e-33 114.3 28.5 5.5e-33 114.3 28.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG51704.1 - 1.2e-09 37.6 9.2 1.2e-09 37.6 9.2 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KXG51704.1 - 7e-07 28.1 3.3 7e-07 28.1 3.3 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 KXG51705.1 - 1.1e-73 248.6 0.0 1.4e-73 248.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2316 PF10078.9 KXG51705.1 - 0.12 12.6 0.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) adh_short PF00106.25 KXG51706.1 - 2.3e-37 128.3 0.0 5.8e-37 127.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG51706.1 - 1.7e-25 90.0 0.0 2.5e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG51706.1 - 3.2e-06 27.2 3.1 3.3e-05 23.9 1.2 2.5 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 KXG51706.1 - 1.5e-05 24.6 0.1 3.6e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TetR_C_35 PF18556.1 KXG51706.1 - 0.089 12.9 0.2 1.6 8.9 0.2 2.6 2 0 0 2 2 2 0 Bacterial Tetracyclin repressor, C-terminal domain LDcluster4 PF18306.1 KXG51706.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 SLOG cluster4 family Abhydrolase_3 PF07859.13 KXG51707.1 - 3.7e-21 76.0 0.0 4.7e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXG51707.1 - 7.4e-12 44.8 0.0 1.2e-11 44.1 0.0 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase FMO-like PF00743.19 KXG51708.1 - 1.4e-17 63.3 0.0 1.6e-16 59.9 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXG51708.1 - 2.8e-14 53.1 0.0 1.3e-13 50.9 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG51708.1 - 4.9e-14 52.3 0.0 7.3e-11 41.8 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG51708.1 - 2.2e-10 40.6 0.0 9e-08 32.2 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXG51708.1 - 5e-08 32.5 0.0 6.8e-06 25.5 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KXG51708.1 - 3.1e-07 29.9 0.0 3.7e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KXG51708.1 - 1.6e-06 28.0 0.0 0.00074 19.2 0.1 3.7 4 0 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXG51708.1 - 6.8e-05 23.4 0.0 0.024 15.2 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG51708.1 - 0.00064 19.7 0.3 10 6.1 0.0 3.9 4 1 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KXG51708.1 - 0.0019 18.3 0.0 0.035 14.2 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KXG51708.1 - 0.01 14.9 0.0 1.4 7.9 0.0 3.2 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.22 KXG51708.1 - 0.017 14.3 0.4 0.66 9.0 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXG51708.1 - 0.03 13.7 0.0 0.88 8.8 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KXG51708.1 - 0.042 14.3 0.0 0.16 12.4 0.0 2.1 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KXG51708.1 - 0.049 12.7 0.1 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Mqo PF06039.15 KXG51708.1 - 0.079 11.5 0.1 6.9 5.1 0.0 2.5 2 1 1 3 3 3 0 Malate:quinone oxidoreductase (Mqo) Lipase_3 PF01764.25 KXG51709.1 - 2.4e-31 108.5 0.0 3.5e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KXG51709.1 - 0.00025 21.0 0.0 0.00048 20.1 0.0 1.4 1 0 0 1 1 1 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 KXG51709.1 - 0.0033 16.7 0.0 0.0053 16.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXG51709.1 - 0.011 16.3 0.1 0.014 16.0 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KXG51709.1 - 0.13 11.9 0.8 0.9 9.2 0.3 2.2 1 1 1 2 2 2 0 PGAP1-like protein PTR2 PF00854.21 KXG51710.1 - 1.7e-79 267.5 7.2 2.2e-79 267.1 7.2 1.1 1 0 0 1 1 1 1 POT family Sugar_tr PF00083.24 KXG51710.1 - 0.7 8.7 20.3 0.29 9.9 6.3 3.2 2 1 0 3 3 3 0 Sugar (and other) transporter COesterase PF00135.28 KXG51711.1 - 5e-82 276.4 0.0 6.3e-82 276.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG51711.1 - 0.00025 21.0 0.6 0.0015 18.5 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Alpha-amylase PF00128.24 KXG51712.1 - 5.3e-68 230.1 1.1 7e-68 229.7 1.1 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.19 KXG51712.1 - 3.9e-32 110.0 0.2 1.1e-31 108.6 0.2 1.8 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.11 KXG51712.1 - 7.1e-31 106.4 0.2 1.8e-30 105.1 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) GHL10 PF02638.15 KXG51712.1 - 0.017 14.2 0.1 0.026 13.6 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 Glyco_hydro_15 PF00723.21 KXG51713.1 - 6.3e-105 351.5 0.0 7.6e-105 351.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KXG51713.1 - 2.4e-31 107.5 0.3 5.6e-31 106.3 0.3 1.7 1 0 0 1 1 1 1 Starch binding domain DUF4774 PF15999.5 KXG51713.1 - 2.9 7.8 8.3 0.5 10.2 3.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4774) MFS_1 PF07690.16 KXG51714.1 - 4.3e-43 147.6 45.2 9.1e-43 146.5 45.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG51714.1 - 4.8e-11 41.8 13.3 4.8e-11 41.8 13.3 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXG51714.1 - 4.7e-09 35.6 11.7 4.7e-09 35.6 11.7 3.0 2 2 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 KXG51714.1 - 6.1 5.0 15.8 0.27 9.5 1.0 2.7 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Sulfatase PF00884.23 KXG51716.1 - 9.6e-63 212.4 0.6 1.3e-62 212.0 0.6 1.2 1 0 0 1 1 1 1 Sulfatase MFS_1 PF07690.16 KXG51716.1 - 2.3e-30 105.7 24.1 3.1e-30 105.3 24.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4976 PF16347.5 KXG51716.1 - 0.024 14.9 0.1 0.056 13.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KXG51716.1 - 0.046 13.3 0.2 9 5.8 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase ADH_N PF08240.12 KXG51717.1 - 1.7e-21 76.2 6.9 2.8e-21 75.4 6.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG51717.1 - 3.6e-17 62.6 0.0 6.2e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXG51717.1 - 0.00014 21.2 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXG51717.1 - 0.0014 18.0 0.1 0.0022 17.4 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.25 KXG51718.1 - 2.5e-15 56.5 0.0 6.4e-15 55.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG51718.1 - 5.4e-14 52.1 0.0 2.5e-13 49.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXG51718.1 - 0.00034 20.6 0.7 0.0012 18.8 0.7 1.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXG51718.1 - 0.0023 17.3 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXG51718.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.4 1 1 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KXG51718.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Fungal_trans PF04082.18 KXG51719.1 - 2.1e-10 40.1 1.0 7.1e-10 38.4 1.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KXG51720.1 - 5.7e-74 249.5 0.0 7.4e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.18 KXG51721.1 - 1.8e-38 132.3 19.4 2.7e-38 131.7 19.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Amidohydro_2 PF04909.14 KXG51721.1 - 3.5e-27 95.9 0.0 2.1e-26 93.4 0.0 2.1 2 1 0 2 2 2 1 Amidohydrolase ketoacyl-synt PF00109.26 KXG51722.1 - 8.9e-88 294.1 0.4 1e-86 290.7 0.4 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXG51722.1 - 6.5e-61 206.6 0.1 1.5e-60 205.4 0.1 1.7 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KXG51722.1 - 1.3e-56 191.4 0.0 4.4e-56 189.6 0.0 2.0 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KXG51722.1 - 2.3e-40 137.3 1.5 7.8e-40 135.6 0.6 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KXG51722.1 - 1.6e-09 37.5 0.1 1.6e-09 37.5 0.1 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase PP-binding PF00550.25 KXG51722.1 - 1.5e-08 34.9 0.0 3.7e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KXG51722.1 - 2.5e-06 27.9 0.0 6.5e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KXG51722.1 - 1.3e-05 24.7 0.1 3.3e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.25 KXG51722.1 - 0.00016 21.2 0.0 0.0024 17.4 0.0 2.6 1 1 0 1 1 1 1 short chain dehydrogenase DUF1442 PF07279.11 KXG51722.1 - 0.054 12.8 0.1 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1442) ACP_syn_III PF08545.10 KXG51722.1 - 0.16 11.8 0.5 3.8 7.4 0.8 3.0 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.22 KXG51723.1 - 1.9e-60 205.0 0.0 2.4e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MBOAT_2 PF13813.6 KXG51724.1 - 1.6e-20 73.1 0.2 3.7e-20 72.0 0.2 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family adh_short PF00106.25 KXG51725.1 - 2.3e-23 82.7 0.0 1.5e-16 60.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXG51725.1 - 7.4e-12 45.3 0.0 2.9e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG51725.1 - 4.2e-07 30.0 0.1 6.6e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXG51725.1 - 0.0011 18.2 0.0 0.03 13.4 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein TPP_enzyme_C PF02775.21 KXG51725.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Cupin_2 PF07883.11 KXG51726.1 - 2.3e-05 24.0 0.2 3.9e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Cupin domain FAD_binding_4 PF01565.23 KXG51728.1 - 4.8e-25 87.9 0.5 9.3e-25 87.0 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain CorA PF01544.18 KXG51729.1 - 8.2e-10 38.5 0.2 1.4e-09 37.7 0.2 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF5516 PF17637.2 KXG51729.1 - 0.14 11.9 0.3 0.35 10.7 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5516) Abhydrolase_6 PF12697.7 KXG51730.1 - 4.8e-14 53.5 0.9 6.4e-14 53.1 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG51730.1 - 0.02 14.2 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Glyco_hydro_72 PF03198.14 KXG51732.1 - 7.6e-130 432.8 7.5 9.8e-130 432.4 7.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KXG51732.1 - 2.5e-26 92.2 6.2 9.8e-26 90.3 6.2 2.1 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 KXG51732.1 - 0.0029 17.1 0.3 0.0073 15.8 0.3 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Herpes_capsid PF06112.11 KXG51732.1 - 0.87 9.6 12.7 2.4 8.2 12.7 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF2406 PF10295.9 KXG51733.1 - 5.9e-23 81.3 0.4 9e-23 80.7 0.4 1.3 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) OPT PF03169.15 KXG51734.1 - 1.1e-166 556.0 49.4 1.3e-166 555.9 49.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CCSMST1 PF15013.6 KXG51734.1 - 3.5 7.8 7.4 0.31 11.2 1.7 2.3 2 0 0 2 2 2 0 CCSMST1 family IMPDH PF00478.25 KXG51735.1 - 1.5e-124 415.5 4.8 1.7e-124 415.3 4.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KXG51735.1 - 3.1e-17 62.8 0.0 3.1e-08 33.9 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 KXG51735.1 - 5.3e-06 25.7 2.4 1e-05 24.8 2.4 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KXG51735.1 - 6.1e-06 25.9 10.4 0.026 13.9 6.2 3.0 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 KXG51735.1 - 0.00012 21.6 3.7 0.0018 17.8 0.3 2.2 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.14 KXG51735.1 - 0.043 13.1 3.1 0.048 13.0 0.4 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Fungal_trans_2 PF11951.8 KXG51736.1 - 0.00015 20.7 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF5309 PF17236.2 KXG51736.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5309) CoA_transf_3 PF02515.17 KXG51737.1 - 2e-108 362.8 0.0 2.2e-108 362.7 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III RisS_PPD PF16524.5 KXG51737.1 - 0.047 13.9 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS DUF1353 PF07087.11 KXG51737.1 - 0.18 11.5 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Fungal_trans PF04082.18 KXG51738.1 - 8.4e-15 54.5 0.0 1.1e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Oxidored_FMN PF00724.20 KXG51739.1 - 5e-33 114.8 0.0 6.9e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family UPF0160 PF03690.13 KXG51739.1 - 0.081 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) SGL PF08450.12 KXG51740.1 - 4.6e-07 29.7 0.1 0.64 9.6 0.0 3.1 1 1 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region ANAPC4_WD40 PF12894.7 KXG51740.1 - 0.044 14.1 0.0 0.39 11.0 0.0 2.3 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain BNR_2 PF13088.6 KXG51741.1 - 2e-09 37.2 0.1 1.6e-06 27.6 0.1 2.8 1 1 0 2 2 2 2 BNR repeat-like domain BNR PF02012.20 KXG51741.1 - 4.5e-06 25.9 11.3 1 9.6 0.0 5.8 6 0 0 6 6 6 4 BNR/Asp-box repeat DUF4185 PF13810.6 KXG51741.1 - 0.022 14.0 1.5 5 6.3 0.1 3.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4185) Sortilin-Vps10 PF15902.5 KXG51741.1 - 0.061 12.1 0.0 0.91 8.2 0.0 2.2 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, BNR_4 PF15892.5 KXG51741.1 - 0.11 11.8 0.0 0.57 9.5 0.0 2.0 1 1 1 2 2 2 0 BNR repeat-containing family member Pyr_redox_2 PF07992.14 KXG51742.1 - 2.6e-30 105.7 0.1 5.9e-29 101.2 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG51742.1 - 2.5e-13 50.4 0.0 1.5e-10 41.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG51742.1 - 2.5e-08 33.6 0.0 4.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG51742.1 - 6.5e-07 28.8 0.0 2.5e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXG51742.1 - 4.6e-06 26.4 0.1 0.062 12.9 0.0 3.9 3 1 1 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXG51742.1 - 9.5e-06 25.7 0.0 0.73 9.8 0.0 3.5 2 1 1 3 3 3 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KXG51742.1 - 5.8e-05 23.5 0.0 0.0036 17.7 0.0 2.9 3 0 0 3 3 3 1 Putative NAD(P)-binding TrkA_N PF02254.18 KXG51742.1 - 0.0001 22.5 0.4 0.04 14.2 0.0 3.3 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_8 PF13450.6 KXG51742.1 - 0.0023 18.1 0.0 0.061 13.6 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXG51742.1 - 0.035 13.0 0.0 0.33 9.8 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Sin_N PF04801.13 KXG51742.1 - 0.075 12.2 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region DUF1188 PF06690.11 KXG51742.1 - 0.12 11.9 0.0 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Sugar_tr PF00083.24 KXG51743.1 - 2.5e-108 362.8 14.6 2.9e-108 362.6 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG51743.1 - 1.9e-23 83.0 15.7 1.9e-23 83.0 15.7 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG51743.1 - 0.0012 17.3 2.8 0.0052 15.3 0.3 2.2 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KXG51743.1 - 0.0044 15.9 4.1 0.03 13.2 0.4 2.7 2 1 1 3 3 3 3 MFS_1 like family Epimerase PF01370.21 KXG51744.1 - 4.5e-13 49.2 0.7 3.8e-11 42.9 0.7 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXG51744.1 - 3.2e-10 39.5 0.1 6.7e-06 25.3 0.1 2.4 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXG51744.1 - 5.2e-10 39.5 0.0 7.7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXG51744.1 - 3.2e-07 30.0 0.1 5.9e-07 29.2 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXG51744.1 - 4.3e-07 29.7 0.1 1.2e-06 28.2 0.1 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KXG51744.1 - 2.1e-06 27.1 0.1 0.013 14.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 KXG51744.1 - 2.1e-05 24.0 0.3 5.3e-05 22.8 0.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG51744.1 - 0.00033 20.6 0.6 0.011 15.6 0.6 2.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXG51744.1 - 0.053 12.6 0.9 0.25 10.5 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MR_MLE_C PF13378.6 KXG51745.1 - 8.3e-50 169.4 0.0 1.2e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KXG51745.1 - 0.00038 20.6 0.0 0.0008 19.6 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KXG51745.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Hexokinase_2 PF03727.16 KXG51746.1 - 0.023 14.1 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Hexokinase Ring_hydroxyl_A PF00848.19 KXG51747.1 - 3.1e-26 92.7 6.1 5e-14 52.8 0.0 2.4 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KXG51747.1 - 5.5e-14 51.9 0.0 1.2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Sulfatase PF00884.23 KXG51748.1 - 2.2e-64 217.8 0.0 2.9e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KXG51748.1 - 1e-18 67.5 7.3 1.9e-18 66.6 4.3 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KXG51748.1 - 4.2e-08 33.2 0.1 1e-07 31.9 0.1 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 KXG51748.1 - 0.0084 16.8 0.6 0.02 15.7 0.6 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Fungal_trans PF04082.18 KXG51749.1 - 3.4e-09 36.1 0.3 5.4e-09 35.5 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXG51750.1 - 1.5e-12 47.1 25.8 1.5e-12 47.1 24.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXG51750.1 - 1.7e-07 31.1 6.0 1.7e-07 31.1 6.0 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF3871 PF12987.7 KXG51750.1 - 0.2 10.5 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) MFS_1 PF07690.16 KXG51751.1 - 6.7e-27 94.3 29.4 6.7e-27 94.3 29.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily PDGLE PF13190.6 KXG51751.1 - 1.2 9.0 3.2 9.9 6.1 0.2 3.0 3 0 0 3 3 3 0 PDGLE domain DUF1772 PF08592.11 KXG51751.1 - 4.3 7.7 11.4 4.8 7.5 1.1 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF1772) adh_short_C2 PF13561.6 KXG51752.1 - 2.6e-41 141.7 0.0 4.1e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG51752.1 - 4.2e-33 114.4 0.0 5.8e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG51752.1 - 1.1e-08 35.2 0.1 2e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.8 KXG51752.1 - 6e-06 25.3 0.0 9.1e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Epimerase PF01370.21 KXG51752.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG51752.1 - 0.13 11.7 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ERG4_ERG24 PF01222.17 KXG51753.1 - 2.4e-58 197.9 12.0 2.9e-58 197.7 12.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KXG51753.1 - 0.4 10.1 8.9 2.1 7.8 8.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Fungal_trans PF04082.18 KXG51754.1 - 5.4e-31 107.6 0.5 8.5e-31 106.9 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH_1 PF00378.20 KXG51755.1 - 1.1e-28 100.2 0.0 1.3e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXG51755.1 - 1.9e-14 53.9 0.0 2.1e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Crystallin PF00525.18 KXG51755.1 - 0.11 12.6 0.1 0.53 10.5 0.0 2.1 2 0 0 2 2 2 0 Alpha crystallin A chain, N terminal Amidase PF01425.21 KXG51757.1 - 2.3e-47 162.0 0.0 5e-45 154.3 0.0 2.3 1 1 1 2 2 2 2 Amidase Sugar_tr PF00083.24 KXG51758.1 - 3.6e-96 322.8 25.5 4.3e-96 322.5 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG51758.1 - 5.3e-31 107.8 48.1 1.8e-26 92.9 26.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG51758.1 - 0.00014 20.5 1.8 0.00014 20.5 1.8 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TPR_19 PF14559.6 KXG51758.1 - 0.063 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Amidohydro_1 PF01979.20 KXG51759.1 - 5.1e-63 213.5 0.0 6.2e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXG51759.1 - 0.0042 16.6 0.4 0.9 8.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Acetyltransf_10 PF13673.7 KXG51760.1 - 2.6e-08 33.9 0.0 4.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG51760.1 - 6.4e-08 32.8 0.0 1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXG51760.1 - 2.3e-06 27.9 0.0 3.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXG51760.1 - 0.00057 20.0 0.0 0.015 15.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG51760.1 - 0.0045 16.9 0.0 0.0088 16.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXG51760.1 - 0.0058 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase SQHop_cyclase_N PF13249.6 KXG51760.1 - 0.15 11.1 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Squalene-hopene cyclase N-terminal domain DUF4951 PF16309.5 KXG51761.1 - 0.1 12.6 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) DUF4179 PF13786.6 KXG51761.1 - 0.14 12.7 2.2 0.21 12.1 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Reeler PF02014.16 KXG51761.1 - 0.17 12.6 0.0 0.21 12.3 0.0 1.2 1 0 0 1 1 1 0 Reeler domain RPW8 PF05659.11 KXG51762.1 - 0.3 10.8 2.3 6.4 6.5 0.7 2.2 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Glyco_hydro_75 PF07335.11 KXG51763.1 - 2.3e-57 193.8 0.3 3.8e-57 193.1 0.3 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Sugar_tr PF00083.24 KXG51764.1 - 4.3e-145 484.0 26.4 4.9e-145 483.8 26.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG51764.1 - 5.9e-25 87.9 34.7 7.6e-19 67.8 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cellulase PF00150.18 KXG51765.1 - 1.4e-16 60.7 0.8 1.8e-16 60.4 0.8 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KXG51765.1 - 0.00058 19.6 0.1 0.00095 18.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_2_C PF02836.17 KXG51765.1 - 0.0007 18.8 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KXG51765.1 - 0.0064 15.9 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 Beta-galactosidase DUF2255 PF10012.9 KXG51765.1 - 0.063 13.4 0.5 0.14 12.3 0.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) AA_permease_2 PF13520.6 KXG51766.1 - 4.6e-48 164.1 55.7 5.9e-48 163.7 55.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG51766.1 - 2.3e-25 89.2 47.3 3e-25 88.8 47.3 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.8 KXG51766.1 - 0.14 12.0 0.7 0.32 10.8 0.7 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) AA_permease PF00324.21 KXG51767.1 - 2.4e-114 382.6 44.3 2.9e-114 382.3 44.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG51767.1 - 2.3e-26 92.6 45.4 2.7e-26 92.4 45.4 1.0 1 0 0 1 1 1 1 Amino acid permease TauD PF02668.16 KXG51768.1 - 6.5e-51 173.7 0.4 7.8e-51 173.4 0.4 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Peptidase_A4 PF01828.17 KXG51770.1 - 1.3e-65 220.8 9.5 1.6e-65 220.5 9.5 1.1 1 0 0 1 1 1 1 Peptidase A4 family Hemerythrin PF01814.23 KXG51771.1 - 2.5e-12 47.6 2.3 3e-12 47.3 2.3 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain SQS_PSY PF00494.19 KXG51772.1 - 9.9e-38 130.1 0.0 1.3e-37 129.8 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Peroxin-22 PF12827.7 KXG51772.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family SHOCT PF09851.9 KXG51772.1 - 2.1 8.2 4.4 0.36 10.6 0.4 1.9 2 0 0 2 2 2 0 Short C-terminal domain DnaJ-X PF14308.6 KXG51773.1 - 5.1e-76 254.8 5.4 5.1e-76 254.8 5.4 3.3 3 2 1 4 4 4 1 X-domain of DnaJ-containing DnaJ PF00226.31 KXG51773.1 - 3.4e-25 88.0 0.2 9.6e-25 86.5 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain OrfB_IS605 PF01385.19 KXG51773.1 - 5.4 7.3 7.6 0.52 10.5 2.0 2.1 2 0 0 2 2 2 0 Probable transposase MARVEL PF01284.23 KXG51774.1 - 3.8e-08 33.5 23.7 5.7e-08 32.9 23.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF1600 PF07667.11 KXG51774.1 - 0.029 14.6 2.0 0.029 14.6 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1600) His_Phos_2 PF00328.22 KXG51775.1 - 2.2e-40 139.2 0.0 2.6e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF2236 PF09995.9 KXG51776.1 - 3.2e-07 30.8 0.0 4.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) NRBF2 PF08961.10 KXG51777.1 - 0.63 9.6 4.3 9.9 5.7 0.1 2.3 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator IMS PF00817.20 KXG51778.1 - 9.3e-44 149.0 0.1 1.7e-43 148.2 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KXG51778.1 - 1.1e-15 58.4 0.5 5e-15 56.2 0.3 2.2 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KXG51778.1 - 7.1e-06 26.0 0.0 2.5e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif BAF PF02961.14 KXG51778.1 - 0.021 15.2 0.1 0.076 13.5 0.0 1.9 1 1 1 2 2 2 0 Barrier to autointegration factor NIBRIN_BRCT_II PF16508.5 KXG51779.1 - 2.2e-35 121.5 0.0 5.1e-35 120.4 0.0 1.6 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KXG51779.1 - 2e-09 37.6 0.2 4.1e-09 36.7 0.2 1.5 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 KXG51779.1 - 0.0075 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain DUF4138 PF13595.6 KXG51779.1 - 0.079 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) Yop-YscD_cpl PF16697.5 KXG51779.1 - 0.11 12.9 0.0 0.39 11.1 0.0 2.0 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Mannosyl_trans PF05007.13 KXG51780.1 - 7.3e-76 255.4 14.7 9.5e-76 255.1 14.7 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KXG51780.1 - 3.9e-09 36.0 20.1 4e-08 32.7 20.1 2.0 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KXG51780.1 - 6.5e-06 26.0 28.8 6.5e-06 26.0 28.8 2.6 1 1 1 2 2 2 1 Glycosyltransferase family 87 DUF3712 PF12505.8 KXG51781.1 - 5.6e-31 107.4 1.5 9.1e-31 106.7 0.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Fungal_trans PF04082.18 KXG51782.1 - 3.7e-16 58.9 0.0 8e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG51782.1 - 3.4e-06 27.1 14.6 6.4e-06 26.2 14.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3913 PF13052.6 KXG51782.1 - 0.2 12.0 0.1 1.1 9.6 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3913) Mannosidase_ig PF17786.1 KXG51783.1 - 2.8e-19 69.5 0.1 1e-18 67.7 0.1 2.0 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KXG51783.1 - 5e-14 52.9 0.1 1.4e-13 51.4 0.1 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KXG51783.1 - 0.00019 21.4 0.0 0.00063 19.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Translin PF01997.16 KXG51784.1 - 1.2e-70 237.7 0.1 1.4e-70 237.4 0.1 1.1 1 0 0 1 1 1 1 Translin family RIF5_SNase_2 PF18189.1 KXG51784.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 TbRIF5 SNase domain 2 RPEL PF02755.15 KXG51785.1 - 2.3e-25 87.5 15.0 6.3e-09 35.2 0.9 3.6 3 0 0 3 3 3 3 RPEL repeat Rotamase_3 PF13616.6 KXG51785.1 - 0.03 14.9 0.5 0.17 12.4 0.2 1.9 1 1 1 2 2 2 0 PPIC-type PPIASE domain PIN_4 PF13638.6 KXG51786.1 - 1.4e-05 25.4 0.0 0.0034 17.7 0.0 2.4 2 0 0 2 2 2 2 PIN domain Rhodanese PF00581.20 KXG51787.1 - 3.7e-15 56.4 0.0 2.5e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain zf-ANAPC11 PF12861.7 KXG51788.1 - 1.8e-46 156.1 11.5 2.1e-46 155.9 11.5 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KXG51788.1 - 7.1e-21 74.2 10.7 9.6e-21 73.8 10.7 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXG51788.1 - 8.1e-08 32.5 15.3 2.4e-06 27.7 15.2 2.5 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXG51788.1 - 0.00013 21.7 4.5 0.00013 21.7 4.5 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXG51788.1 - 0.002 18.1 8.0 0.0085 16.1 3.9 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 KXG51788.1 - 0.0021 17.8 11.9 0.07 12.9 8.5 2.7 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KXG51788.1 - 0.0071 16.5 16.3 0.14 12.3 16.3 3.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 KXG51788.1 - 0.0089 15.9 12.5 0.3 11.0 12.6 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 KXG51788.1 - 0.017 14.9 1.4 0.21 11.5 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4 PF00097.25 KXG51788.1 - 0.058 13.3 15.4 0.37 10.7 15.4 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXG51788.1 - 0.086 13.0 1.5 0.086 13.0 1.5 2.4 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KXG51788.1 - 0.22 11.2 14.1 0.33 10.6 11.8 2.2 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KXG51788.1 - 0.27 11.2 15.3 2.1 8.4 15.4 2.5 1 1 1 2 2 2 0 zinc-RING finger domain YacG PF03884.14 KXG51788.1 - 0.33 10.7 0.4 0.33 10.7 0.4 2.7 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Prok-RING_4 PF14447.6 KXG51788.1 - 0.34 10.8 12.6 26 4.8 12.8 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.29 KXG51788.1 - 0.61 10.0 13.7 2.6 8.0 13.7 2.0 1 1 0 1 1 1 0 PHD-finger RecR PF02132.15 KXG51788.1 - 0.87 9.2 7.0 1.4 8.6 0.1 3.0 3 0 0 3 3 3 0 RecR protein zf-C2H2_9 PF16293.5 KXG51788.1 - 1.1 9.1 7.2 4.6 7.2 0.1 3.2 2 1 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-HIT PF04438.16 KXG51788.1 - 1.2 9.1 7.4 0.29 11.1 1.0 2.4 3 0 0 3 3 2 0 HIT zinc finger zf-RING_11 PF17123.5 KXG51788.1 - 1.7 8.4 13.7 3.4 7.5 10.8 2.7 2 1 0 2 2 2 0 RING-like zinc finger Opy2 PF09463.10 KXG51788.1 - 1.9 8.9 10.7 1.9 8.9 6.5 2.5 2 1 0 2 2 2 0 Opy2 protein RINGv PF12906.7 KXG51788.1 - 2.2 8.5 13.2 1.9 8.7 10.7 2.2 1 1 1 2 2 2 0 RING-variant domain zf-RING-like PF08746.11 KXG51788.1 - 2.5 8.5 11.7 1.8 8.9 8.6 2.2 1 1 1 2 2 2 0 RING-like domain zf-HC5HC2H PF13771.6 KXG51788.1 - 4.1 7.7 12.1 24 5.2 11.9 2.3 1 1 1 2 2 2 0 PHD-like zinc-binding domain Kinesin PF00225.23 KXG51790.1 - 3.4e-111 371.4 0.9 3.4e-111 371.4 0.9 2.2 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KXG51790.1 - 2e-25 89.5 0.3 1.4e-24 86.8 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 KXG51790.1 - 2.3e-08 34.5 1.5 2.3e-08 34.5 1.5 4.7 3 2 2 5 5 5 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.12 KXG51790.1 - 0.0053 16.8 21.3 0.12 12.4 0.0 6.0 2 1 5 8 8 8 2 Baculovirus polyhedron envelope protein, PEP, C terminus DAP_B PF07930.12 KXG51790.1 - 1.9 8.5 5.2 19 5.1 0.7 2.9 2 0 0 2 2 2 0 D-aminopeptidase, domain B Gp-FAR-1 PF05823.12 KXG51790.1 - 7.3 6.9 10.7 2.5 8.4 0.3 4.0 3 2 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) UPF0183 PF03676.14 KXG51791.1 - 1.8e-52 179.0 0.0 8.6e-35 120.8 0.0 2.9 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) ABC_membrane PF00664.23 KXG51792.1 - 4.7e-80 269.2 39.0 1e-43 150.0 14.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXG51792.1 - 6.6e-67 224.2 0.0 8.7e-33 113.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXG51792.1 - 4.7e-13 49.1 0.3 0.00047 19.7 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXG51792.1 - 7.5e-08 32.0 0.8 0.0039 16.9 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KXG51792.1 - 4.4e-07 29.1 0.8 0.045 12.6 0.0 3.6 4 0 0 4 4 4 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KXG51792.1 - 6.6e-07 29.4 0.0 0.024 14.5 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KXG51792.1 - 1e-06 29.1 0.3 0.047 14.0 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KXG51792.1 - 4.5e-06 26.6 0.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KXG51792.1 - 8.4e-06 25.5 0.2 0.19 11.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KXG51792.1 - 9.4e-05 22.8 4.5 0.32 11.4 0.1 3.5 3 2 0 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 KXG51792.1 - 0.00011 22.2 0.2 4.3 7.1 0.1 4.1 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KXG51792.1 - 0.0002 21.5 0.9 1.5 9.1 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KXG51792.1 - 0.0002 21.1 0.1 0.86 9.3 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_7 PF12775.7 KXG51792.1 - 0.00046 19.7 0.0 0.13 11.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region G-alpha PF00503.20 KXG51792.1 - 0.0025 17.1 0.0 2.2 7.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_23 PF13476.6 KXG51792.1 - 0.0035 17.9 0.0 2.5 8.5 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXG51792.1 - 0.0037 17.4 0.2 2.1 8.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXG51792.1 - 0.0047 17.3 0.1 18 5.8 0.0 4.2 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KXG51792.1 - 0.0071 16.6 0.5 0.78 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KXG51792.1 - 0.014 14.7 0.0 5.9 6.1 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 KXG51792.1 - 0.019 15.0 0.1 5.4 7.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KXG51792.1 - 0.023 14.8 0.1 2.7 8.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DEAD PF00270.29 KXG51792.1 - 0.032 14.0 1.3 1.8 8.3 0.0 3.5 5 0 0 5 5 5 0 DEAD/DEAH box helicase APS_kinase PF01583.20 KXG51792.1 - 0.052 13.4 0.0 3.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase ATP-synt_ab PF00006.25 KXG51792.1 - 0.056 13.1 0.3 14 5.3 0.0 2.8 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 KXG51792.1 - 0.056 14.0 0.0 22 5.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXG51792.1 - 0.082 13.3 0.0 4.8 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KXG51792.1 - 0.13 11.4 0.4 4.3 6.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 KXG51792.1 - 0.56 10.3 3.6 1.9 8.5 0.2 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain tRNA-synt_1 PF00133.22 KXG51793.1 - 1.7e-158 528.6 0.0 2.3e-158 528.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Bac_rhodopsin PF01036.18 KXG51793.1 - 3.8e-31 108.4 12.9 6.6e-31 107.6 12.9 1.3 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Anticodon_1 PF08264.13 KXG51793.1 - 9.1e-21 74.4 0.9 1.6e-20 73.6 0.9 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KXG51793.1 - 7.3e-20 71.1 0.0 1.4e-12 47.1 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KXG51793.1 - 0.004 16.7 0.0 0.0085 15.6 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 DHOase PF12890.7 KXG51793.1 - 0.17 11.8 0.0 0.49 10.3 0.0 1.7 2 0 0 2 2 2 0 Dihydro-orotase-like Methyltransf_23 PF13489.6 KXG51795.1 - 1.7e-14 54.0 0.0 2.7e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG51795.1 - 2.8e-09 37.6 0.0 1e-08 35.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG51795.1 - 0.00017 22.3 0.0 0.0031 18.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG51795.1 - 0.00027 21.5 0.0 0.00093 19.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG51795.1 - 0.0016 18.3 0.0 0.0066 16.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXG51795.1 - 0.0086 15.6 0.0 0.021 14.3 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KXG51795.1 - 0.0098 15.5 0.0 0.041 13.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KXG51795.1 - 0.017 14.4 0.0 0.11 11.7 0.0 2.0 1 1 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 KXG51795.1 - 0.17 11.2 0.0 4 6.7 0.0 2.5 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Ribosomal_S5 PF00333.20 KXG51796.1 - 3.1e-25 87.9 1.1 8.3e-25 86.6 0.5 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KXG51796.1 - 3.9e-23 80.7 0.0 6.8e-23 79.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 KXG51796.1 - 3.3 8.3 16.3 8 7.1 16.3 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Mpv17_PMP22 PF04117.12 KXG51797.1 - 6.5e-22 77.5 1.5 1.3e-21 76.5 1.5 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family IF4E PF01652.18 KXG51798.1 - 6.5e-53 178.8 0.5 8.3e-53 178.4 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PTR2 PF00854.21 KXG51799.1 - 1e-92 311.1 8.2 1.9e-92 310.1 8.2 1.4 1 1 0 1 1 1 1 POT family Syntaxin PF00804.25 KXG51800.1 - 9.4e-12 45.0 13.2 1.4e-11 44.5 13.2 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KXG51800.1 - 1e-09 38.3 0.7 1e-09 38.3 0.7 2.6 3 0 0 3 3 3 1 SNARE domain T7SS_ESX_EspC PF10824.8 KXG51800.1 - 0.0056 17.1 6.0 7.7 7.1 0.0 3.9 2 1 2 4 4 4 1 Excreted virulence factor EspC, type VII ESX diderm Spore_III_AB PF09548.10 KXG51800.1 - 0.011 15.8 0.7 0.038 14.1 0.3 2.1 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) CD225 PF04505.12 KXG51800.1 - 0.012 15.7 0.9 0.026 14.6 0.9 1.6 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Syntaxin_2 PF14523.6 KXG51800.1 - 0.012 15.9 5.3 0.012 15.9 5.3 2.6 2 1 0 2 2 2 0 Syntaxin-like protein VitD-bind_III PF09164.10 KXG51800.1 - 0.012 15.5 0.1 0.06 13.3 0.1 2.1 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Phage_holin_3_3 PF16083.5 KXG51800.1 - 0.018 15.2 0.2 0.028 14.5 0.2 1.3 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III DUF2207 PF09972.9 KXG51800.1 - 0.069 11.9 2.0 0.79 8.4 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) BshC PF10079.9 KXG51800.1 - 0.22 10.2 6.5 0.12 11.1 4.3 1.6 1 1 0 1 1 1 0 Bacillithiol biosynthesis BshC PBP1_TM PF14812.6 KXG51800.1 - 0.28 11.6 2.6 0.68 10.3 0.0 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Prominin PF05478.11 KXG51800.1 - 0.29 9.0 6.9 1.4 6.8 0.1 2.3 1 1 0 2 2 2 0 Prominin COG5 PF10392.9 KXG51800.1 - 0.3 11.3 7.5 0.22 11.7 0.4 3.1 3 1 0 3 3 3 0 Golgi transport complex subunit 5 Syntaxin-6_N PF09177.11 KXG51800.1 - 0.5 10.9 9.0 2.1 9.0 2.6 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Mobilization_B PF17511.2 KXG51800.1 - 1.2 9.5 9.7 0.7 10.3 4.6 2.6 2 1 0 2 2 2 0 Mobilization protein B IZUMO PF15005.6 KXG51800.1 - 2.4 8.7 4.4 2.1 8.8 1.6 2.0 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Synaptobrevin PF00957.21 KXG51800.1 - 2.6 7.9 6.5 0.74 9.6 1.4 2.4 2 0 0 2 2 2 0 Synaptobrevin Fib_alpha PF08702.10 KXG51800.1 - 2.8 8.1 11.0 1.2 9.3 1.3 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family HisKA_3 PF07730.13 KXG51800.1 - 3.3 8.3 7.8 2 9.0 0.1 3.6 2 2 2 4 4 4 0 Histidine kinase Laminin_II PF06009.12 KXG51800.1 - 3.9 7.5 15.0 1.9 8.5 2.6 3.0 2 1 1 3 3 3 0 Laminin Domain II FliJ PF02050.16 KXG51800.1 - 4.6 7.5 17.1 2.7 8.3 3.7 3.1 2 1 1 3 3 3 0 Flagellar FliJ protein LXG PF04740.12 KXG51800.1 - 5.7 6.6 10.8 3.8 7.2 1.5 2.3 2 0 0 2 2 2 0 LXG domain of WXG superfamily V_ATPase_I PF01496.19 KXG51800.1 - 6.8 4.5 7.7 5.8 4.7 5.4 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family BolA PF01722.18 KXG51801.1 - 5.1e-30 103.6 3.3 6.5e-30 103.2 3.3 1.1 1 0 0 1 1 1 1 BolA-like protein AMP-binding PF00501.28 KXG51802.1 - 6.1e-65 219.5 0.0 8.7e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG51802.1 - 7.9e-14 52.4 0.1 2.8e-13 50.6 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Adenylsucc_synt PF00709.21 KXG51802.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase YpzI PF14140.6 KXG51803.1 - 2.9e-06 26.9 17.1 1.7 8.5 0.1 6.3 6 0 0 6 6 6 5 YpzI-like protein Frag1 PF10277.9 KXG51805.1 - 3e-44 151.2 13.1 3e-44 151.2 13.1 2.2 1 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family MARVEL PF01284.23 KXG51805.1 - 4.5e-06 26.7 19.0 4.5e-06 26.7 19.0 3.5 2 1 1 3 3 3 2 Membrane-associating domain DUF3087 PF11286.8 KXG51805.1 - 7.5 6.0 8.8 0.18 11.3 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3087) RNB PF00773.19 KXG51806.1 - 1.5e-50 172.4 0.0 9.6e-38 130.3 0.0 2.3 1 1 1 2 2 2 2 RNB domain FAD_binding_4 PF01565.23 KXG51807.1 - 3.1e-22 78.8 0.5 8.8e-22 77.3 0.9 1.6 2 0 0 2 2 2 1 FAD binding domain SIT PF15330.6 KXG51808.1 - 0.14 12.6 0.3 0.14 12.6 0.3 1.9 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT MARVEL PF01284.23 KXG51808.1 - 0.33 11.0 13.2 0.69 9.9 13.2 1.5 1 1 0 1 1 1 0 Membrane-associating domain Cys_Met_Meta_PP PF01053.20 KXG51809.1 - 3.6e-47 160.7 0.0 6.1e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme ThiS PF02597.20 KXG51809.1 - 5.4e-07 30.1 0.0 1.4e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 ThiS family Aminotran_5 PF00266.19 KXG51809.1 - 0.033 13.1 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXG51809.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II TRP PF06011.12 KXG51810.1 - 1.5e-39 135.9 21.4 4.9e-37 127.7 21.4 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXG51810.1 - 7.5e-14 52.3 0.0 1.2e-13 51.7 0.0 1.3 1 0 0 1 1 1 1 ML-like domain zf-RING_2 PF13639.6 KXG51811.1 - 3.3e-08 33.7 6.1 3.3e-08 33.7 6.1 2.6 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXG51811.1 - 2.7e-05 23.9 6.3 2.7e-05 23.9 6.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXG51811.1 - 3.1e-05 23.6 6.3 9.1e-05 22.1 6.3 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KXG51811.1 - 0.00074 19.8 11.6 0.00087 19.5 7.6 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXG51811.1 - 0.0083 16.0 6.0 0.0083 16.0 6.0 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXG51811.1 - 0.011 15.7 12.9 0.015 15.3 4.7 2.9 2 0 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.8 KXG51811.1 - 0.027 14.6 4.8 0.027 14.6 4.8 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KXG51811.1 - 0.032 14.3 5.0 0.19 11.8 2.7 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 KXG51811.1 - 0.45 10.7 6.4 1.5 9.0 6.4 1.9 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 KXG51811.1 - 0.74 10.2 10.1 0.075 13.4 5.2 2.0 2 0 0 2 2 2 0 RING-like domain Fungal_trans PF04082.18 KXG51812.1 - 1.7e-05 24.0 0.0 2.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG51812.1 - 6e-05 23.1 12.0 9.6e-05 22.4 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Reprolysin_4 PF13583.6 KXG51813.1 - 1.6e-30 106.2 1.7 2.9e-30 105.5 1.7 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KXG51813.1 - 5.6e-29 101.7 4.1 8.9e-29 101.0 4.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KXG51813.1 - 4.2e-17 62.7 0.4 6.6e-17 62.0 0.4 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KXG51813.1 - 0.0045 16.9 0.2 0.024 14.5 0.2 2.0 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 KXG51813.1 - 0.0072 16.8 0.1 0.017 15.7 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EcKinase PF02958.20 KXG51814.1 - 1.7e-09 37.4 0.0 2.9e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 KXG51814.1 - 6.5e-08 32.8 0.5 4.8e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG51814.1 - 0.0055 16.3 0.0 0.052 13.1 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Fungal_trans_2 PF11951.8 KXG51815.1 - 1e-09 37.7 1.5 2.1e-09 36.7 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG51815.1 - 2.6e-05 24.3 9.7 4.4e-05 23.5 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT_2 PF13646.6 KXG51815.1 - 0.081 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats zf-rbx1 PF12678.7 KXG51815.1 - 1.7 9.0 5.9 13 6.2 0.2 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain MFS_1 PF07690.16 KXG51816.1 - 1.2e-13 50.7 8.3 2.5e-13 49.7 8.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KXG51817.1 - 1e-06 27.8 0.1 6.1e-06 25.3 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.21 KXG51818.1 - 2.1e-86 290.7 0.0 2.7e-86 290.3 0.0 1.1 1 0 0 1 1 1 1 Amidase Arrestin_N PF00339.29 KXG51819.1 - 0.0071 16.4 0.0 0.016 15.3 0.0 1.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_N PF04425.12 KXG51819.1 - 0.089 11.5 0.6 0.19 10.4 0.6 1.5 1 0 0 1 1 1 0 Bul1 N terminus MFS_1 PF07690.16 KXG51821.1 - 1.6e-31 109.5 30.5 1.6e-31 109.5 30.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KXG51822.1 - 6.5e-18 64.7 0.0 1.3e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.28 KXG51824.1 - 2.3e-87 294.0 0.0 3.7e-87 293.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG51824.1 - 2.2e-08 34.2 0.7 9.5e-08 32.2 0.7 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXG51824.1 - 3e-05 23.6 0.1 6.6e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family PSDC PF12588.8 KXG51825.1 - 2e-57 193.1 0.0 2.9e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KXG51825.1 - 1e-37 129.6 0.0 2.6e-37 128.3 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 KXG51825.1 - 0.011 15.5 1.2 0.37 10.7 0.2 2.4 2 0 0 2 2 2 0 Biotin-lipoyl like Peptidase_M23 PF01551.22 KXG51825.1 - 0.095 12.9 0.0 0.31 11.3 0.0 1.9 1 0 0 1 1 1 0 Peptidase family M23 RnfC_N PF13375.6 KXG51825.1 - 0.12 12.3 0.1 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 KXG51825.1 - 0.19 11.6 0.6 0.58 10.0 0.1 2.0 2 0 0 2 2 2 0 Biotin-requiring enzyme MFS_1 PF07690.16 KXG51826.1 - 3.4e-30 105.2 27.6 3.4e-30 105.2 27.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3522 PF12036.8 KXG51826.1 - 0.13 12.6 0.2 0.13 12.6 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3522) Ribosomal_L7Ae PF01248.26 KXG51827.1 - 4e-26 90.6 0.0 4.8e-26 90.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KXG51827.1 - 7e-05 22.9 0.1 7.6e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KXG51827.1 - 0.0049 16.7 0.0 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain Chlorosome_CsmC PF11098.8 KXG51828.1 - 0.043 13.8 2.7 0.054 13.5 2.7 1.2 1 0 0 1 1 1 0 Chlorosome envelope protein C Collagen_mid PF15984.5 KXG51828.1 - 0.33 10.7 21.1 1.7 8.4 7.7 1.9 1 1 0 1 1 1 0 Bacterial collagen, middle region VPS13_C PF16909.5 KXG51828.1 - 8.8 6.1 6.3 37 4.0 1.1 2.0 1 1 1 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal FAD_binding_3 PF01494.19 KXG51829.1 - 6.2e-14 52.0 0.0 1.3e-13 50.9 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXG51829.1 - 4e-06 26.6 0.7 0.0001 22.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG51829.1 - 2.3e-05 24.5 0.0 6.8e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG51829.1 - 9.7e-05 21.7 0.1 0.00027 20.3 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG51829.1 - 0.0033 16.7 0.1 0.0054 16.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KXG51829.1 - 0.0059 16.6 0.2 0.088 12.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXG51829.1 - 0.0083 15.2 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXG51829.1 - 0.0087 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXG51829.1 - 0.012 14.3 0.0 0.024 13.3 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KXG51829.1 - 0.022 15.3 0.1 0.11 13.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KXG51829.1 - 0.086 11.9 0.0 4.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase AT_hook PF02178.19 KXG51830.1 - 4.5e-06 25.9 24.9 0.033 14.0 2.9 4.2 3 0 0 3 3 3 3 AT hook motif Fungal_trans PF04082.18 KXG51831.1 - 4.9e-34 117.6 3.0 6.3e-24 84.4 3.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG51831.1 - 3.1e-06 27.2 9.7 7.1e-06 26.1 9.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UDPGP PF01704.18 KXG51832.1 - 1.1e-190 633.7 0.1 1.2e-190 633.5 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.13 KXG51832.1 - 0.0068 16.6 0.1 0.022 14.9 0.0 1.8 2 0 0 2 2 2 1 Pilus assembly protein, PilO C2 PF00168.30 KXG51833.1 - 7.4e-75 247.8 0.3 1.3e-19 70.4 0.0 5.7 6 0 0 6 6 6 5 C2 domain SMP_LBD PF17047.5 KXG51833.1 - 0.00014 21.4 0.0 0.00043 19.8 0.0 1.8 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain FKBP_C PF00254.28 KXG51833.1 - 0.1 12.9 0.1 0.56 10.6 0.0 2.3 3 0 0 3 3 3 0 FKBP-type peptidyl-prolyl cis-trans isomerase Amidohydro_3 PF07969.11 KXG51834.1 - 4e-76 257.4 0.2 4.6e-76 257.2 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXG51834.1 - 9.2e-11 41.6 0.0 1.7e-06 27.6 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.16 KXG51835.1 - 4.9e-25 88.2 28.3 4.9e-25 88.2 28.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_1 PF00515.28 KXG51837.1 - 1.3e-44 148.2 26.6 1.7e-06 27.6 0.1 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 KXG51837.1 - 9.9e-38 127.9 14.5 3.3e-20 71.8 0.3 2.8 2 0 0 2 2 2 2 STI1 domain TPR_2 PF07719.17 KXG51837.1 - 7.7e-34 113.1 27.1 9.8e-05 22.2 0.1 9.2 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 KXG51837.1 - 1.4e-18 66.3 21.2 0.00041 20.0 0.0 8.2 5 2 3 8 8 8 5 TPR repeat TPR_12 PF13424.6 KXG51837.1 - 2e-18 66.4 18.6 1.9e-06 28.1 0.2 6.4 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXG51837.1 - 3.2e-15 55.0 28.5 9e-06 25.5 0.3 8.2 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 KXG51837.1 - 1.8e-13 50.9 17.0 0.0049 17.5 0.0 6.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXG51837.1 - 3e-11 43.7 20.3 0.029 14.9 0.1 7.4 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXG51837.1 - 4.8e-11 42.5 16.6 0.39 11.6 0.0 8.5 6 2 4 10 10 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXG51837.1 - 2.2e-10 40.1 7.5 0.23 11.9 0.0 7.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXG51837.1 - 7.1e-10 38.9 9.6 0.00094 19.3 0.1 5.2 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXG51837.1 - 2.3e-08 33.5 7.0 0.0028 17.6 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXG51837.1 - 1.7e-06 28.0 2.6 0.11 12.6 0.0 5.1 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 KXG51837.1 - 0.0002 21.8 20.0 0.23 12.2 0.1 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXG51837.1 - 0.00027 20.7 15.4 0.0089 15.9 0.2 6.9 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_20 PF14561.6 KXG51837.1 - 0.0057 17.0 17.7 0.0081 16.5 0.1 4.9 4 2 1 5 5 5 2 Tetratricopeptide repeat DHC_N2 PF08393.13 KXG51837.1 - 0.052 12.7 1.0 0.36 9.9 0.1 2.1 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 DUF5113 PF17140.4 KXG51837.1 - 0.24 11.2 8.8 6.9 6.4 0.1 4.4 4 1 1 5 5 5 0 Domain of unknown function (DUF5113) RPN7 PF10602.9 KXG51837.1 - 0.31 10.7 14.4 6.1 6.5 2.6 5.1 2 2 1 3 3 3 0 26S proteasome subunit RPN7 PPR PF01535.20 KXG51837.1 - 0.73 10.2 2.1 1.2e+02 3.3 0.0 4.4 5 1 1 6 6 4 0 PPR repeat MIT PF04212.18 KXG51837.1 - 1.4 9.1 22.5 1.6 8.8 0.2 6.4 6 2 0 6 6 5 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.6 KXG51837.1 - 1.4 9.4 9.3 4.6 7.7 0.0 4.4 2 2 2 4 4 4 0 Alkyl sulfatase dimerisation TPR_3 PF07720.12 KXG51837.1 - 1.6 8.8 9.9 2.4 8.3 0.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat RNA_pol_Rpc34 PF05158.12 KXG51838.1 - 9.7e-114 380.2 0.0 1.1e-113 380.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_46 PF15977.5 KXG51838.1 - 0.042 13.9 0.1 0.096 12.7 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding MarR PF01047.22 KXG51838.1 - 0.1 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 MarR family PadR PF03551.14 KXG51838.1 - 0.13 12.3 0.1 0.58 10.2 0.1 2.1 1 1 1 2 2 2 0 Transcriptional regulator PadR-like family ING PF12998.7 KXG51839.1 - 3.3e-24 85.4 2.6 5.5e-24 84.7 2.6 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KXG51839.1 - 3.3e-05 23.7 9.6 5.9e-05 22.9 9.6 1.4 1 0 0 1 1 1 1 PHD-finger TFIIA PF03153.13 KXG51839.1 - 0.012 15.6 11.3 0.018 15.0 11.4 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-HC5HC2H PF13771.6 KXG51839.1 - 0.036 14.3 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KXG51839.1 - 0.43 10.2 4.7 0.92 9.1 4.7 1.6 1 0 0 1 1 1 0 PHD-finger Peptidase_S64 PF08192.11 KXG51840.1 - 7.3e-05 21.5 0.2 0.00021 19.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase family S64 Trypsin_2 PF13365.6 KXG51840.1 - 0.0012 19.8 0.0 0.014 16.3 0.0 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain EzrA PF06160.12 KXG51840.1 - 0.0057 14.9 0.7 0.0084 14.3 0.7 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Pico_P2A PF00947.19 KXG51840.1 - 0.014 15.5 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Picornavirus core protein 2A Rab_bind PF16704.5 KXG51840.1 - 0.018 15.0 0.1 0.059 13.4 0.0 1.8 2 0 0 2 2 2 0 Rab binding domain DUF1664 PF07889.12 KXG51840.1 - 0.023 14.7 0.7 0.064 13.3 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Trypsin PF00089.26 KXG51840.1 - 0.048 13.5 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Trypsin XhlA PF10779.9 KXG51840.1 - 0.068 13.4 4.4 0.086 13.1 0.4 2.7 3 0 0 3 3 3 0 Haemolysin XhlA PRKG1_interact PF15898.5 KXG51840.1 - 0.099 13.6 1.0 0.19 12.7 1.0 1.4 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF2390 PF09523.10 KXG51840.1 - 0.1 13.0 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Sec2p PF06428.11 KXG51840.1 - 0.1 12.6 0.9 3.2 7.8 0.2 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p FlaC_arch PF05377.11 KXG51840.1 - 0.12 12.8 1.2 7.3 7.1 0.4 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Rx_N PF18052.1 KXG51840.1 - 0.12 12.6 0.4 3.1 8.1 0.1 2.2 2 0 0 2 2 2 0 Rx N-terminal domain Fib_alpha PF08702.10 KXG51840.1 - 0.18 12.0 1.4 0.37 11.0 1.4 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Nup54 PF13874.6 KXG51840.1 - 0.22 11.6 0.9 0.48 10.5 0.8 1.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 EMP24_GP25L PF01105.24 KXG51840.1 - 0.24 11.4 1.0 0.39 10.6 0.7 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Snapin_Pallidin PF14712.6 KXG51840.1 - 0.26 11.8 1.1 1.3 9.5 0.6 2.1 2 0 0 2 2 2 0 Snapin/Pallidin DUF812 PF05667.11 KXG51840.1 - 0.54 9.1 4.5 0.065 12.1 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) 2C_adapt PF08793.10 KXG51841.1 - 0.27 11.5 3.4 18 5.6 0.1 3.2 3 0 0 3 3 3 0 2-cysteine adaptor domain Methyltransf_25 PF13649.6 KXG51842.1 - 1.1e-06 29.2 0.0 1.3e-05 25.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG51842.1 - 4.9e-06 26.5 0.0 2.5e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG51842.1 - 0.0025 17.6 0.0 0.026 14.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXG51842.1 - 0.0076 15.7 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 KXG51842.1 - 0.043 14.5 0.0 6.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KXG51842.1 - 0.052 13.1 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain AMPK1_CBM PF16561.5 KXG51843.1 - 6.9e-05 23.0 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase KAR9 PF08580.10 KXG51843.1 - 1.9 7.0 5.5 2.2 6.7 5.5 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 RNA_pol_Rpb2_6 PF00562.28 KXG51844.1 - 6.3e-123 410.7 0.1 9.3e-123 410.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXG51844.1 - 3.4e-60 203.0 0.0 6.1e-60 202.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KXG51844.1 - 3e-46 157.4 0.0 5.1e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KXG51844.1 - 2.7e-33 114.2 0.0 6.1e-33 113.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KXG51844.1 - 2.9e-25 88.2 0.3 7.2e-25 87.0 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KXG51844.1 - 3.9e-24 84.7 1.0 1.2e-23 83.2 1.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KXG51844.1 - 1.1e-21 77.1 0.1 3.3e-21 75.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 KXG51844.1 - 0.22 12.3 0.0 0.45 11.3 0.0 1.5 1 0 0 1 1 1 0 MRN-interacting protein CTNNBL PF08216.11 KXG51845.1 - 3.2e-39 133.3 1.7 6.8e-39 132.2 0.4 2.3 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Mo25 PF08569.11 KXG51845.1 - 0.0045 16.4 0.4 0.0078 15.6 0.4 1.5 1 0 0 1 1 1 1 Mo25-like NTP_transf_5 PF14907.6 KXG51845.1 - 0.064 12.9 0.2 0.12 12.0 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase Fungal_trans PF04082.18 KXG51846.1 - 3.6e-22 78.7 0.4 6.4e-22 77.8 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Swi3 PF07962.12 KXG51846.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 Pkinase PF00069.25 KXG51847.1 - 2e-17 63.5 0.0 2.9e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG51847.1 - 4.8e-17 62.1 0.0 6.5e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXG51847.1 - 0.0037 17.2 0.4 0.0076 16.2 0.4 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXG51847.1 - 0.019 14.6 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 KXG51847.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like MORN_2 PF07661.13 KXG51847.1 - 0.16 12.3 0.1 0.42 11.0 0.1 1.7 1 0 0 1 1 1 0 MORN repeat variant NAPRTase PF04095.16 KXG51848.1 - 2.2e-53 181.4 0.4 4.8e-52 177.0 0.4 2.2 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KXG51848.1 - 1.3e-32 112.9 0.2 2.4e-32 112.0 0.2 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Fungal_trans PF04082.18 KXG51852.1 - 8.1e-05 21.8 0.1 0.00023 20.3 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain DJ-1_PfpI PF01965.24 KXG51853.1 - 6.1e-16 58.6 0.0 7.7e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family MFS_1 PF07690.16 KXG51854.1 - 5.2e-18 65.1 17.8 7.4e-18 64.6 17.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1772 PF08592.11 KXG51854.1 - 0.018 15.4 1.3 1.1 9.5 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Glyco_hydro_28 PF00295.17 KXG51855.1 - 6.3e-30 104.3 1.0 8.2e-30 104.0 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 KXG51855.1 - 9.8e-05 22.3 6.2 0.011 15.6 1.9 3.8 1 1 2 3 3 3 2 Pectate lyase superfamily protein Sulfatase PF00884.23 KXG51856.1 - 1.4e-43 149.5 0.3 3.7e-41 141.5 0.3 2.4 1 1 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KXG51856.1 - 2.1e-07 31.2 0.9 7.3e-07 29.4 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KXG51856.1 - 1.1e-05 25.2 0.0 0.0025 17.4 0.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 KXG51856.1 - 0.001 19.8 0.0 0.0024 18.6 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 KXG51856.1 - 0.018 14.1 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) FAD_binding_3 PF01494.19 KXG51858.1 - 2e-26 93.1 0.9 1.3e-25 90.4 0.9 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXG51858.1 - 4.9e-07 29.3 0.1 1.4e-05 24.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG51858.1 - 4.9e-05 22.7 0.4 0.0011 18.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG51858.1 - 0.00012 22.3 0.1 0.00046 20.4 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXG51858.1 - 0.00015 22.2 2.9 0.0028 18.2 0.5 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXG51858.1 - 0.00043 19.7 0.9 0.048 12.9 0.1 2.6 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 KXG51858.1 - 0.0017 18.0 1.8 0.0029 17.2 0.5 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase TrkA_N PF02254.18 KXG51858.1 - 0.0017 18.6 0.1 0.0035 17.6 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Lycopene_cycl PF05834.12 KXG51858.1 - 0.0079 15.3 0.8 0.092 11.8 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KXG51858.1 - 0.01 15.1 0.2 0.049 12.9 0.1 2.1 3 0 0 3 3 3 0 Thi4 family ApbA PF02558.16 KXG51858.1 - 0.014 15.1 0.1 0.029 14.0 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KXG51858.1 - 0.03 13.0 0.2 0.055 12.2 0.1 1.4 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 KXG51858.1 - 0.033 13.6 0.2 0.093 12.1 0.2 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase IMPDH PF00478.25 KXG51858.1 - 0.069 12.1 0.2 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain FAD_binding_2 PF00890.24 KXG51858.1 - 0.15 11.1 0.4 0.27 10.3 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain Nucleopor_Nup85 PF07575.13 KXG51859.1 - 9.2e-26 90.5 0.0 2.8e-18 65.8 0.0 3.0 2 1 0 2 2 2 2 Nup85 Nucleoporin TGF_beta_GS PF08515.12 KXG51859.1 - 2 8.0 4.8 0.35 10.4 0.5 2.1 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Fungal_trans_2 PF11951.8 KXG51861.1 - 2.9e-07 29.7 0.0 3.9e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 KXG51862.1 - 3.1e-70 236.0 14.0 3.1e-70 236.0 14.0 1.8 2 0 0 2 2 2 1 RTA1 like protein ADH_N PF08240.12 KXG51863.1 - 4.9e-22 77.9 0.7 7.8e-22 77.2 0.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG51863.1 - 1.4e-17 63.8 0.0 2.8e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG51863.1 - 5e-07 30.8 0.0 8.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXG51863.1 - 0.0067 15.8 0.8 0.011 15.1 0.8 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXG51863.1 - 0.061 12.6 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADIP PF11559.8 KXG51864.1 - 7.6e-42 143.0 7.5 7.6e-42 143.0 7.5 2.8 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 KXG51864.1 - 0.0011 18.5 9.9 0.0011 18.5 9.9 2.8 3 0 0 3 3 3 1 Golgin subfamily A member 5 TTRAP PF14203.6 KXG51864.1 - 0.029 14.4 1.3 0.1 12.6 0.1 2.6 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein FlaC_arch PF05377.11 KXG51864.1 - 0.87 10.0 4.2 3.1 8.3 0.3 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TPR_2 PF07719.17 KXG51865.1 - 2.1e-11 43.0 7.3 0.0044 17.0 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXG51865.1 - 3.1e-07 29.9 4.8 0.38 10.6 0.6 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat LRR_4 PF12799.7 KXG51865.1 - 9.3e-07 29.1 3.8 1.1 9.7 0.0 5.9 6 1 0 6 6 4 1 Leucine Rich repeats (2 copies) F-box PF00646.33 KXG51865.1 - 2.2e-06 27.4 0.0 6.7e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 F-box domain TPR_19 PF14559.6 KXG51865.1 - 8e-06 26.3 4.4 0.0021 18.5 1.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXG51865.1 - 1.9e-05 25.1 5.2 0.14 13.0 0.2 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat F-box-like PF12937.7 KXG51865.1 - 2.5e-05 24.1 0.0 5.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like TPR_7 PF13176.6 KXG51865.1 - 2.5e-05 24.0 1.0 0.054 13.5 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXG51865.1 - 0.00034 20.8 2.5 0.27 11.6 1.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXG51865.1 - 0.00034 21.2 5.1 0.041 14.5 1.8 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXG51865.1 - 0.0015 18.7 1.3 0.81 10.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXG51865.1 - 0.0088 15.7 1.2 0.048 13.4 0.0 2.6 2 1 1 3 3 3 1 TPR repeat TPR_9 PF13371.6 KXG51865.1 - 0.012 15.8 7.6 0.099 12.8 1.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXG51865.1 - 0.022 15.0 2.7 7.9 7.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat LRR_8 PF13855.6 KXG51865.1 - 0.028 14.2 2.0 3.6 7.4 0.0 4.5 6 0 0 6 6 6 0 Leucine rich repeat TPR_21 PF09976.9 KXG51865.1 - 0.26 11.0 1.7 0.52 10.0 1.7 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 KXG51865.1 - 0.29 11.1 3.4 24 5.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXG51865.1 - 2 9.2 5.3 8.2 7.3 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat IDO PF01231.18 KXG51866.1 - 2.8e-34 118.7 0.0 3.9e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Glyco_transf_34 PF05637.12 KXG51867.1 - 2.8e-06 27.2 0.5 2.8e-05 24.0 0.5 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 KXG51867.1 - 1.1e-05 25.6 0.0 2.1e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase GP57 PF17594.2 KXG51867.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 Aminotran_5 PF00266.19 KXG51867.1 - 0.16 10.9 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V Glyco_transf_34 PF05637.12 KXG51868.1 - 9.8e-08 32.0 0.0 1.6e-05 24.7 0.0 2.3 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family PET117 PF15786.5 KXG51869.1 - 4e-23 81.5 0.6 4.8e-23 81.2 0.6 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial RPA_interact_M PF14767.6 KXG51869.1 - 0.0082 16.7 0.1 0.01 16.4 0.1 1.1 1 0 0 1 1 1 1 Replication protein A interacting middle V-ATPase_G PF03179.15 KXG51870.1 - 4.8e-33 113.8 16.3 5.8e-33 113.6 16.3 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 KXG51870.1 - 0.014 14.8 10.4 0.014 14.8 10.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ATP-synt_B PF00430.18 KXG51870.1 - 0.11 12.6 21.7 0.082 13.0 11.5 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF1834 PF08873.11 KXG51870.1 - 0.12 12.1 0.7 0.15 11.8 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) HypD PF01924.16 KXG51870.1 - 0.16 11.0 1.7 0.19 10.8 1.7 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family Ntox34 PF15606.6 KXG51870.1 - 0.53 10.4 2.7 3.7 7.7 0.3 2.1 2 0 0 2 2 2 0 Bacterial toxin 34 V-ATPase_G_2 PF16999.5 KXG51870.1 - 1.1 9.7 16.7 2.2 8.7 16.7 1.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit RRF PF01765.19 KXG51870.1 - 1.5 8.7 13.6 3.1 7.7 13.6 1.5 1 1 0 1 1 1 0 Ribosome recycling factor vATP-synt_E PF01991.18 KXG51870.1 - 4.4 6.7 17.4 0.64 9.4 6.6 2.1 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit ATP11 PF06644.11 KXG51870.1 - 5.8 6.6 12.1 6.5 6.5 12.1 1.0 1 0 0 1 1 1 0 ATP11 protein DUF4407 PF14362.6 KXG51870.1 - 8.8 5.6 10.2 9.2 5.5 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF883 PF05957.13 KXG51870.1 - 9.1 7.0 11.4 18 6.0 4.4 2.1 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PGAP1 PF07819.13 KXG51871.1 - 5.6e-06 26.3 0.0 9.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KXG51871.1 - 7e-06 26.1 0.0 8.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 KXG51871.1 - 8.8e-05 22.1 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KXG51871.1 - 0.0025 18.5 0.2 0.003 18.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG51871.1 - 0.0033 17.1 0.1 0.038 13.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 KXG51871.1 - 0.004 16.4 0.0 0.006 15.8 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 KXG51871.1 - 0.021 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.11 KXG51871.1 - 0.039 13.3 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Arrestin_N PF00339.29 KXG51872.1 - 7.3e-12 45.6 0.1 3.4e-09 36.9 0.1 3.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain UL42 PF17638.2 KXG51872.1 - 2.9 7.9 9.5 0.088 12.8 1.2 2.6 2 0 0 2 2 2 0 HCMV UL42 Pyr_redox_2 PF07992.14 KXG51874.1 - 3.6e-46 157.7 0.1 4.9e-46 157.3 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KXG51874.1 - 5e-16 58.4 0.0 1.4e-15 57.0 0.0 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KXG51874.1 - 2.2e-12 47.4 0.2 8.7e-11 42.2 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 KXG51874.1 - 0.00012 21.9 0.0 0.00051 19.9 0.0 2.0 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.6 KXG51874.1 - 0.00027 21.5 0.0 0.00075 20.0 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal DUF1188 PF06690.11 KXG51874.1 - 0.00043 19.9 0.1 0.0016 18.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) NAD_binding_9 PF13454.6 KXG51874.1 - 0.0022 18.0 0.7 1.9 8.5 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding TrkA_N PF02254.18 KXG51874.1 - 0.06 13.6 1.0 2.2 8.6 0.0 2.8 3 0 0 3 3 3 0 TrkA-N domain RPA43_OB PF17875.1 KXG51875.1 - 2.1e-40 138.2 0.1 2.1e-40 138.2 0.1 2.7 3 0 0 3 3 3 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KXG51875.1 - 4.1e-08 33.5 0.0 1e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 AP3D1 PF06375.11 KXG51875.1 - 0.9 9.8 18.9 0.21 11.8 10.1 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 CPSF100_C PF13299.6 KXG51875.1 - 7.9 6.6 9.5 15 5.7 4.4 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DnaJ PF00226.31 KXG51876.1 - 3.1e-16 59.3 0.1 5.2e-16 58.5 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain INO80_Ies4 PF08193.11 KXG51877.1 - 3e-62 210.8 20.9 3e-62 210.8 20.9 1.4 1 1 0 1 1 1 1 INO80 complex subunit Ies4 CLTH PF10607.9 KXG51878.1 - 2.2e-33 115.2 0.0 4.3e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KXG51878.1 - 1.3e-24 86.6 0.1 2.1e-24 85.9 0.1 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KXG51878.1 - 0.00046 20.0 0.2 0.0016 18.3 0.0 2.1 2 0 0 2 2 2 1 LisH Fib_alpha PF08702.10 KXG51879.1 - 0.0016 18.6 18.2 0.0017 18.6 3.7 3.3 1 1 0 2 2 2 1 Fibrinogen alpha/beta chain family BRE1 PF08647.11 KXG51879.1 - 0.0096 16.0 10.6 0.0096 16.0 10.6 2.9 2 1 1 3 3 3 1 BRE1 E3 ubiquitin ligase DUF948 PF06103.11 KXG51879.1 - 0.056 13.7 8.2 1.1 9.6 0.7 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DivIVA PF05103.13 KXG51879.1 - 0.065 13.3 26.5 2.3 8.3 12.4 3.7 2 1 2 4 4 4 0 DivIVA protein IKKbetaNEMObind PF12179.8 KXG51879.1 - 0.26 11.3 2.2 1.3 9.1 0.1 3.1 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain Mod_r PF07200.13 KXG51879.1 - 0.33 11.0 28.8 0.15 12.2 16.5 3.6 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein CALCOCO1 PF07888.11 KXG51879.1 - 0.39 9.5 33.7 0.4 9.5 30.8 2.3 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like RPW8 PF05659.11 KXG51879.1 - 0.52 10.0 4.3 3.2 7.4 0.2 2.4 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 CENP-H PF05837.12 KXG51879.1 - 1.3 9.4 30.2 0.38 11.2 9.2 4.0 1 1 3 4 4 4 0 Centromere protein H (CENP-H) Fez1 PF06818.15 KXG51879.1 - 1.4 9.4 30.3 0.28 11.6 22.6 2.7 2 1 1 3 3 3 0 Fez1 Vps5 PF09325.10 KXG51879.1 - 1.5 8.3 17.7 9.4 5.7 17.7 2.5 1 1 0 1 1 1 0 Vps5 C terminal like Phage_GP20 PF06810.11 KXG51879.1 - 1.6 8.5 15.3 3.7 7.4 3.5 2.8 2 1 1 3 3 3 0 Phage minor structural protein GP20 TMPIT PF07851.13 KXG51879.1 - 3.9 6.6 16.0 5.6 6.1 5.3 2.3 1 1 1 2 2 2 0 TMPIT-like protein YabA PF06156.13 KXG51879.1 - 7.7 7.2 22.5 8.5 7.1 4.9 3.9 1 1 3 4 4 4 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 KXG51879.1 - 7.7 6.5 34.5 0.33 11.0 9.3 4.2 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 KXG51879.1 - 8.4 4.4 20.5 1 7.5 15.1 2.0 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA GAS PF13851.6 KXG51879.1 - 8.5 5.7 29.6 66 2.8 24.6 3.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 KXG51879.1 - 9.5 6.2 22.1 10 6.2 6.1 3.4 2 1 1 3 3 3 0 Laminin Domain II Methyltransf_16 PF10294.9 KXG51880.1 - 3.2e-16 59.5 0.0 1.5e-15 57.4 0.0 1.8 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KXG51880.1 - 0.011 16.4 0.0 0.027 15.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KXG51880.1 - 0.013 14.9 0.0 0.031 13.7 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXG51880.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 KXG51880.1 - 0.031 14.0 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KXG51880.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S24e PF01282.19 KXG51881.1 - 1.8e-35 120.7 0.1 3.3e-35 119.9 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.6 KXG51881.1 - 0.0079 16.1 1.3 0.011 15.5 1.0 1.4 1 1 0 1 1 1 1 RRXRR protein Zn_clus PF00172.18 KXG51882.1 - 1.1e-08 35.1 6.5 2e-08 34.2 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.21 KXG51883.1 - 1.1e-37 129.7 0.0 1.6e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KXG51883.1 - 9e-15 54.3 0.0 1.9e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UDPGP PF01704.18 KXG51884.1 - 2.2e-56 191.3 0.0 3e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KXG51884.1 - 0.14 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain zf-CCHC PF00098.23 KXG51885.1 - 1.3e-45 151.5 53.8 2.4e-07 30.5 0.9 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KXG51885.1 - 1e-09 37.9 39.2 0.041 13.6 0.4 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 KXG51885.1 - 7e-09 35.5 36.8 0.014 15.3 0.0 7.0 5 2 1 6 6 6 4 Zinc knuckle zf-CCHC_5 PF14787.6 KXG51885.1 - 0.00058 19.5 41.0 0.019 14.6 0.8 7.0 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 KXG51885.1 - 5.9 6.8 48.2 0.68 9.8 1.4 6.9 6 1 1 7 7 7 0 Zinc knuckle Rad51 PF08423.11 KXG51886.1 - 1.1e-110 368.9 0.0 1.4e-110 368.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KXG51886.1 - 2.2e-10 40.4 0.0 2.9e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KXG51886.1 - 3.1e-08 33.2 0.0 7.2e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 KXG51886.1 - 3.5e-08 33.9 2.7 4.7e-08 33.5 0.8 2.3 3 0 0 3 3 3 1 Helix-hairpin-helix domain AAA_25 PF13481.6 KXG51886.1 - 0.00025 20.7 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KXG51886.1 - 0.073 12.4 0.1 0.91 8.8 0.1 2.2 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain RRM_Rrp7 PF17799.1 KXG51887.1 - 3e-31 108.4 0.0 8.4e-31 106.9 0.0 1.7 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 KXG51887.1 - 1.5e-26 92.8 8.0 1.5e-26 92.8 8.0 2.1 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_1 PF00076.22 KXG51887.1 - 0.003 17.3 0.0 1.5 8.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dak1_2 PF13684.6 KXG51887.1 - 0.08 12.0 0.3 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Dihydroxyacetone kinase family DUF5093 PF17011.5 KXG51887.1 - 0.089 13.1 5.6 0.63 10.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5093) UPF0172 PF03665.13 KXG51887.1 - 0.21 11.6 2.2 0.21 11.6 0.5 1.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0172) TFB6 PF17110.5 KXG51888.1 - 1.5e-33 115.9 0.0 2.4e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH RRM_1 PF00076.22 KXG51889.1 - 3.7e-45 151.6 0.0 7.6e-17 60.9 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXG51889.1 - 7.5e-06 25.8 0.1 0.0016 18.4 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KXG51889.1 - 9.8e-05 22.3 0.0 0.0012 18.8 0.0 2.4 3 0 0 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 KXG51889.1 - 0.00011 22.0 0.0 0.058 13.3 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KXG51889.1 - 0.00055 20.0 0.2 0.052 13.7 0.0 2.9 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 KXG51889.1 - 0.011 15.3 0.0 0.069 12.8 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0154 PF03672.13 KXG51889.1 - 0.22 11.6 1.6 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) LisH PF08513.11 KXG51891.1 - 4.5e-05 23.3 0.3 4.5e-05 23.3 0.3 1.6 2 0 0 2 2 2 1 LisH TRAPP PF04051.16 KXG51892.1 - 8.6e-36 122.8 0.1 2.3e-35 121.5 0.0 1.6 1 1 1 2 2 2 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 KXG51892.1 - 0.01 14.7 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF4250 PF14056.6 KXG51892.1 - 0.081 12.9 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) WD40 PF00400.32 KXG51893.1 - 4.7e-40 134.8 8.1 2.4e-07 31.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG51893.1 - 1.1e-10 41.7 0.1 0.07 13.4 0.0 5.3 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXG51893.1 - 0.006 15.9 0.0 3.7 6.8 0.0 3.2 2 1 0 3 3 3 2 WD40-like domain Nucleoporin_N PF08801.11 KXG51893.1 - 0.015 14.1 0.1 0.93 8.2 0.0 2.5 2 1 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.8 KXG51893.1 - 0.24 10.0 1.0 16 4.0 0.1 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Glyco_hydro_47 PF01532.20 KXG51895.1 - 2.4e-117 392.7 0.0 3e-117 392.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AP_endonuc_2 PF01261.24 KXG51896.1 - 6.4e-28 97.6 0.0 9.2e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AIG2_2 PF13772.6 KXG51897.1 - 0.0016 18.8 0.0 0.013 15.8 0.0 2.2 2 0 0 2 2 2 1 AIG2-like family GGACT PF06094.12 KXG51897.1 - 0.0081 16.8 0.0 0.016 15.8 0.0 1.6 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Pribosyltran PF00156.27 KXG51898.1 - 2.9e-16 59.4 0.0 3.9e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Thi4 PF01946.17 KXG51898.1 - 0.11 11.8 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Ribonuc_L-PSP PF01042.21 KXG51900.1 - 3.9e-40 136.6 0.1 4.3e-40 136.5 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Membr_traf_MHD PF10540.9 KXG51901.1 - 6.9e-21 75.0 1.5 1.5e-10 41.4 0.7 3.6 2 1 1 3 3 3 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KXG51901.1 - 6.4e-15 55.3 0.0 1.4e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF4720 PF15846.5 KXG51901.1 - 0.091 12.6 0.5 4.3 7.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4720) NDUF_B8 PF05821.11 KXG51902.1 - 2.9e-08 33.8 0.6 4.6e-08 33.1 0.7 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.23 KXG51903.1 - 1.9e-63 214.3 0.2 3.3e-63 213.5 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXG51903.1 - 4.1e-19 69.0 0.0 1.4e-18 67.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG51903.1 - 2.4e-10 40.7 0.0 5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 KXG51903.1 - 1.1e-07 32.1 6.8 1.1e-07 32.1 6.8 2.5 2 0 0 2 2 2 1 HSA DEAD PF00270.29 KXG51903.1 - 0.00018 21.3 0.0 0.00044 20.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 KXG51903.1 - 0.024 14.2 0.1 0.076 12.6 0.0 1.8 2 0 0 2 2 2 0 DEAD_2 DUF2981 PF11200.8 KXG51903.1 - 0.77 9.4 4.9 0.26 11.0 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) Clr5 PF14420.6 KXG51904.1 - 3.4e-13 49.6 1.8 6.1e-13 48.8 1.8 1.4 1 0 0 1 1 1 1 Clr5 domain ADH_zinc_N PF00107.26 KXG51905.1 - 6.1e-27 94.2 2.3 1.1e-26 93.4 2.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG51905.1 - 6.3e-11 43.5 0.1 1.1e-10 42.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG51905.1 - 2.6e-06 27.3 0.0 2.2e-05 24.3 0.0 2.6 3 1 1 4 4 4 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KXG51905.1 - 0.025 13.9 2.0 0.05 12.9 2.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KXG51905.1 - 0.035 14.4 0.0 0.062 13.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain PagL PF09411.10 KXG51907.1 - 0.056 13.6 0.1 0.12 12.6 0.1 1.6 1 1 0 1 1 1 0 Lipid A 3-O-deacylase (PagL) DUF3824 PF12868.7 KXG51907.1 - 0.46 11.1 6.9 0.71 10.5 6.9 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Glyco_tranf_2_3 PF13641.6 KXG51908.1 - 4.8e-23 82.3 0.3 5.4e-23 82.1 0.3 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXG51908.1 - 7.6e-07 28.8 0.1 0.001 18.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXG51908.1 - 0.052 13.4 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Oxysterol_BP PF01237.18 KXG51909.1 - 4.8e-134 446.9 0.1 7.8e-133 442.9 0.0 2.2 2 0 0 2 2 2 1 Oxysterol-binding protein ATP12 PF07542.11 KXG51909.1 - 5.2e-44 149.4 0.5 1.4e-43 148.1 0.5 1.8 1 0 0 1 1 1 1 ATP12 chaperone protein Ank_5 PF13857.6 KXG51909.1 - 4.4e-14 52.4 0.2 8.1e-08 32.4 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXG51909.1 - 1.4e-11 44.8 0.0 2.2e-08 34.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 KXG51909.1 - 8.3e-11 42.3 0.4 1.7e-10 41.3 0.4 1.6 1 0 0 1 1 1 1 PH domain Ank PF00023.30 KXG51909.1 - 1.4e-10 41.1 0.1 0.015 15.7 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KXG51909.1 - 1.2e-08 34.5 0.1 0.007 16.8 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KXG51909.1 - 1.2e-07 32.1 0.1 8.8e-05 23.0 0.0 3.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) PH_8 PF15409.6 KXG51909.1 - 7.8e-07 29.3 0.8 1.8e-06 28.1 0.8 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KXG51909.1 - 6.5e-05 23.3 2.3 6.5e-05 23.3 2.3 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain zf-Mss51 PF13824.6 KXG51910.1 - 5.5e-29 100.0 7.2 1.2e-28 99.0 7.2 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF3011 PF11218.8 KXG51910.1 - 0.011 15.8 0.1 0.018 15.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3011) zf-MYND PF01753.18 KXG51910.1 - 0.031 14.4 0.4 0.031 14.4 0.4 1.8 2 0 0 2 2 2 0 MYND finger HsbA PF12296.8 KXG51911.1 - 0.058 13.8 3.3 0.11 13.0 3.3 1.4 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Ras PF00071.22 KXG51913.1 - 1.9e-29 102.4 0.0 2.9e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXG51913.1 - 4.2e-17 62.5 0.0 7.4e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG51913.1 - 1.1e-05 24.9 0.0 0.00014 21.4 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family ADH_N PF08240.12 KXG51914.1 - 8.2e-35 119.0 0.2 1.8e-34 117.9 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG51914.1 - 1.6e-22 79.9 0.3 2.5e-22 79.3 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXG51914.1 - 1.3e-07 31.3 0.3 2.5e-07 30.4 0.3 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KXG51914.1 - 0.00051 19.7 0.0 0.00081 19.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 KXG51914.1 - 0.00069 19.0 0.9 0.0012 18.2 0.9 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KXG51914.1 - 0.0019 19.3 0.0 0.0035 18.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KXG51914.1 - 0.0094 15.2 0.1 0.018 14.3 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 KXG51914.1 - 0.034 14.9 0.1 0.07 13.8 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KXG51914.1 - 0.05 13.0 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4403 PF14356.6 KXG51914.1 - 0.056 12.1 0.0 0.081 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) FAD-oxidase_C PF02913.19 KXG51915.1 - 7.2e-61 206.0 0.1 1.5e-60 205.0 0.1 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXG51915.1 - 5.3e-36 123.4 0.0 1.1e-35 122.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Het-C PF07217.11 KXG51916.1 - 5.6e-238 791.1 0.0 7.3e-238 790.7 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C FAM76 PF16046.5 KXG51917.1 - 8.4 5.6 7.8 1 8.6 3.6 1.5 2 0 0 2 2 2 0 FAM76 protein Clr5 PF14420.6 KXG51918.1 - 1.3e-12 47.8 2.0 1.9e-12 47.2 0.3 2.3 2 0 0 2 2 2 1 Clr5 domain YozE_SAM_like PF06855.12 KXG51918.1 - 0.04 14.1 0.5 11 6.3 0.0 3.0 3 0 0 3 3 3 0 YozE SAM-like fold DUF2407_C PF13373.6 KXG51918.1 - 0.084 13.0 0.1 0.22 11.7 0.1 1.7 1 0 0 1 1 1 0 DUF2407 C-terminal domain WD40 PF00400.32 KXG51919.1 - 0.025 15.5 0.2 0.025 15.5 0.2 6.1 7 0 0 7 7 7 0 WD domain, G-beta repeat Kelch_2 PF07646.15 KXG51919.1 - 0.094 12.7 1.1 1.3 9.2 0.4 3.3 2 0 0 2 2 2 0 Kelch motif DUF4614 PF15391.6 KXG51919.1 - 0.25 11.4 5.6 0.93 9.5 5.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Kelch_6 PF13964.6 KXG51919.1 - 0.33 11.3 2.2 2 8.9 0.1 3.4 4 0 0 4 4 4 0 Kelch motif RNA_pol_N PF01194.17 KXG51920.1 - 1.5e-30 105.2 1.4 1.8e-30 105.0 1.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit XK-related PF09815.9 KXG51921.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 XK-related protein Fer4_13 PF13370.6 KXG51921.1 - 0.47 11.0 4.9 5.6 7.6 0.0 4.1 3 2 1 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I Abhydrolase_6 PF12697.7 KXG51922.1 - 4.8e-14 53.5 1.7 6.8e-14 53.0 1.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG51922.1 - 1.2e-12 48.1 0.0 4.9e-12 46.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG51922.1 - 6.2e-07 28.9 0.0 9.4e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KXG51922.1 - 0.0071 16.5 0.2 0.017 15.2 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain Phage_tail_APC PF16778.5 KXG51922.1 - 0.0076 16.1 0.1 4.3 7.3 0.0 2.5 2 0 0 2 2 2 2 Phage tail assembly chaperone protein PGAP1 PF07819.13 KXG51922.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Ser_hydrolase PF06821.13 KXG51922.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_5 PF12695.7 KXG51922.1 - 0.081 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Palm_thioest PF02089.15 KXG51922.1 - 0.17 11.7 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Methyltransf_2 PF00891.18 KXG51923.1 - 2.6e-24 85.7 0.0 3.3e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KXG51923.1 - 0.0016 19.1 0.0 0.0026 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG51923.1 - 0.011 16.4 0.0 0.021 15.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_2 PF02230.16 KXG51924.1 - 8.3e-16 58.4 0.0 1.2e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Methyltransf_2 PF00891.18 KXG51925.1 - 1.9e-21 76.4 0.0 2.3e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain SnoaL_3 PF13474.6 KXG51925.1 - 0.058 13.7 0.1 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like domain MFS_1 PF07690.16 KXG51926.1 - 1e-41 143.0 44.4 1.6e-41 142.4 43.4 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG51926.1 - 3.4e-16 58.8 15.3 5.5e-16 58.1 15.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXG51926.1 - 6.6e-13 48.3 15.4 6.6e-13 48.3 15.4 3.2 3 1 1 4 4 4 1 Sugar (and other) transporter OATP PF03137.20 KXG51926.1 - 3.2e-05 22.4 21.3 0.00079 17.8 14.3 3.1 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Sperm_Ag_HE2 PF05324.13 KXG51926.1 - 0.13 12.8 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 Sperm antigen HE2 GMC_oxred_N PF00732.19 KXG51927.1 - 2e-55 188.3 0.2 2.5e-55 187.9 0.2 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG51927.1 - 1e-32 113.6 0.0 1.8e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Helo_like_N PF17111.5 KXG51928.1 - 0.0021 17.5 5.1 0.0028 17.0 0.1 3.0 3 1 0 3 3 3 2 Fungal N-terminal domain of STAND proteins Rieske PF00355.26 KXG51929.1 - 5.6e-07 29.4 0.0 1.2e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain RNase_T PF00929.24 KXG51930.1 - 1.9e-08 35.0 0.0 1.6e-07 32.0 0.0 2.1 1 1 0 1 1 1 1 Exonuclease Glutaredoxin PF00462.24 KXG51931.1 - 4.9e-19 68.3 0.0 1.3e-17 63.8 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KXG51931.1 - 8e-12 45.1 0.0 2.2e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 KXG51931.1 - 0.00049 20.4 0.0 0.013 15.8 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like TauD PF02668.16 KXG51932.1 - 3.9e-46 158.0 0.4 6.4e-46 157.3 0.4 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KXG51932.1 - 1.2e-06 29.1 0.0 3.5e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KXG51932.1 - 0.0014 17.8 0.0 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 CsiD Mito_carr PF00153.27 KXG51933.1 - 4e-63 209.4 2.3 2.3e-20 72.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 KXG51933.1 - 0.011 15.9 0.0 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Tubulin PF00091.25 KXG51934.1 - 1.4e-53 182.0 0.0 2.1e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXG51934.1 - 6.7e-45 152.3 0.0 1e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KXG51934.1 - 0.029 14.1 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain MS_channel PF00924.18 KXG51935.1 - 9.7e-26 90.6 2.3 2.1e-25 89.5 2.3 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 KXG51935.1 - 0.00026 20.3 0.0 0.00064 19.1 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KXG51935.1 - 0.0013 18.1 0.3 0.0034 16.8 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXG51935.1 - 0.0022 17.8 0.0 0.0069 16.2 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXG51935.1 - 0.017 15.6 0.2 0.048 14.1 0.2 1.8 1 0 0 1 1 1 0 EF-hand domain pair Pkinase PF00069.25 KXG51936.1 - 1.1e-57 195.4 0.0 7.6e-39 133.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG51936.1 - 3.2e-26 92.2 0.0 3e-19 69.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KXG51936.1 - 1.5e-12 47.7 0.0 2.7e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KXG51936.1 - 1.2e-07 31.3 0.0 0.00015 21.2 0.0 2.6 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KXG51936.1 - 2.2e-06 27.8 0.0 0.0041 17.1 0.2 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXG51936.1 - 0.0039 16.6 0.0 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXG51936.1 - 0.02 13.8 0.0 0.02 13.8 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Tsc35 PF15079.6 KXG51936.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Testis-specific protein 35 PAS_9 PF13426.7 KXG51936.1 - 0.085 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 PAS domain Seadorna_VP7 PF07387.11 KXG51936.1 - 0.11 11.5 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 KXG51936.1 - 0.14 11.8 0.0 21 4.6 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Fungal_trans PF04082.18 KXG51937.1 - 8.9e-21 74.1 0.1 1.4e-20 73.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GMC_oxred_N PF00732.19 KXG51938.1 - 8.9e-41 140.2 0.0 1.3e-33 116.7 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG51938.1 - 1.3e-36 126.3 0.2 1.9e-36 125.7 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXG51938.1 - 5e-09 35.7 1.6 4.9e-08 32.5 1.6 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG51938.1 - 9.3e-07 28.4 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG51938.1 - 5.8e-06 26.1 0.1 6.7e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXG51938.1 - 2.1e-05 24.0 0.0 0.047 12.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG51938.1 - 2.3e-05 24.5 1.2 7.7e-05 22.8 0.9 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXG51938.1 - 0.00024 20.3 0.0 0.0005 19.2 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXG51938.1 - 0.00061 19.1 0.1 0.0012 18.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KXG51938.1 - 0.0027 16.5 0.2 0.0051 15.6 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KXG51938.1 - 0.0096 15.0 0.1 0.047 12.8 0.1 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KXG51938.1 - 0.026 13.8 0.1 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KXG51938.1 - 0.064 13.8 0.6 0.13 12.8 0.6 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXG51938.1 - 0.091 11.6 0.1 0.2 10.4 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase Yeast-kill-tox PF09207.11 KXG51939.1 - 0.044 14.4 0.7 0.06 14.0 0.7 1.3 1 0 0 1 1 1 0 Yeast killer toxin Sugar_tr PF00083.24 KXG51941.1 - 6.9e-109 364.7 22.1 9.2e-109 364.3 22.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG51941.1 - 6.1e-22 78.0 25.0 2.5e-20 72.7 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 KXG51941.1 - 0.0011 18.8 0.2 0.0028 17.5 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KXG51941.1 - 0.0034 17.3 0.1 0.0084 16.0 0.1 1.7 1 0 0 1 1 1 1 F-box PRANC PF09372.10 KXG51941.1 - 0.02 15.2 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 PRANC domain F-box PF00646.33 KXG51941.1 - 0.036 13.9 0.6 0.082 12.8 0.3 1.8 1 1 0 1 1 1 0 F-box domain Phe_tRNA-synt_N PF02912.18 KXG51941.1 - 0.16 12.0 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Hexapep_2 PF14602.6 KXG51942.1 - 2.4e-14 52.8 10.1 7.9e-11 41.5 1.7 2.6 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KXG51942.1 - 5.7e-14 51.2 11.8 2e-11 43.1 1.9 3.7 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KXG51942.1 - 1.5e-12 47.5 0.1 3.3e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase 2OG-FeII_Oxy PF03171.20 KXG51943.1 - 9.7e-21 74.2 0.0 2.7e-20 72.7 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXG51943.1 - 4.3e-17 63.0 0.0 7e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.16 KXG51944.1 - 1.6e-38 132.6 26.7 1.6e-38 132.6 26.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MWFE PF15879.5 KXG51944.1 - 0.19 11.9 0.1 0.19 11.9 0.1 2.7 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit MFS_1 PF07690.16 KXG51945.1 - 3e-38 131.6 45.1 1.2e-36 126.4 45.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG51945.1 - 0.0054 15.6 12.5 0.0054 15.6 12.5 3.9 3 2 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KXG51945.1 - 0.098 11.5 27.7 0.48 9.2 7.0 2.3 2 0 0 2 2 2 0 MFS_1 like family Peptidase_M24 PF00557.24 KXG51946.1 - 2.7e-39 135.1 0.0 3.4e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 3Beta_HSD PF01073.19 KXG51947.1 - 1e-43 149.4 0.0 2e-39 135.3 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXG51947.1 - 1.5e-18 67.1 0.5 6.6e-16 58.5 0.0 2.4 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG51947.1 - 1.5e-13 50.9 0.2 4.4e-11 42.8 0.1 2.8 3 1 0 3 3 3 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXG51947.1 - 1.9e-10 40.4 0.0 5.6e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KXG51947.1 - 5.1e-06 25.8 0.1 1.4e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXG51947.1 - 0.067 12.3 0.0 0.32 10.1 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein UQ_con PF00179.26 KXG51948.1 - 4e-38 130.2 0.0 2.2e-31 108.4 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UEV PF05743.13 KXG51948.1 - 1.3e-07 31.5 0.0 8.6e-05 22.4 0.0 2.8 3 0 0 3 3 3 2 UEV domain UFC1 PF08694.11 KXG51948.1 - 0.017 14.8 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 KXG51948.1 - 0.037 14.3 0.1 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 RWD domain RhoGAP PF00620.27 KXG51949.1 - 9.7e-36 122.9 0.4 1.7e-35 122.1 0.4 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KXG51949.1 - 1.3e-25 89.3 42.3 5.4e-11 42.6 6.0 4.7 5 0 0 5 5 5 4 LIM domain DUF1272 PF06906.11 KXG51949.1 - 0.0045 17.0 0.1 0.0045 17.0 0.1 4.0 3 1 1 4 4 4 1 Protein of unknown function (DUF1272) zinc_ribbon_12 PF11331.8 KXG51949.1 - 2.6 7.9 9.7 0.29 11.0 0.1 3.4 3 0 0 3 3 3 0 Probable zinc-ribbon domain Desulfoferrod_N PF06397.12 KXG51949.1 - 9.3 6.0 6.8 0.47 10.1 0.3 2.3 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain Peptidase_S10 PF00450.22 KXG51950.1 - 2.1e-56 192.2 0.1 2.5e-56 191.9 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Nbl1_Borealin_N PF10444.9 KXG51951.1 - 2.1e-18 65.7 3.6 2.1e-18 65.7 3.6 1.8 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal VWA_2 PF13519.6 KXG51952.1 - 2.4e-19 70.0 0.1 7.6e-19 68.3 0.1 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KXG51952.1 - 0.00023 21.5 0.3 0.00037 20.8 0.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KXG51952.1 - 0.00082 19.2 0.1 0.0012 18.7 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KXG51952.1 - 0.042 13.8 0.1 0.18 11.8 0.1 2.2 1 0 0 1 1 1 0 Ubiquitin interaction motif Sybindin PF04099.12 KXG51953.1 - 3.3e-46 156.8 0.0 5.9e-46 155.9 0.0 1.4 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KXG51953.1 - 1.5e-06 28.3 0.0 2.4e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Abhydrolase_2 PF02230.16 KXG51954.1 - 4.6e-20 72.4 0.0 3.6e-13 49.8 0.0 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KXG51954.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family AMP-binding PF00501.28 KXG51955.1 - 1.1e-72 245.0 0.0 1.4e-72 244.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.16 KXG51956.1 - 9.3e-35 120.2 43.1 9.3e-35 120.2 43.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Vps62 PF06101.11 KXG51956.1 - 0.12 10.6 0.0 0.18 10.0 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 62 ABC2_membrane PF01061.24 KXG51957.1 - 1.4e-88 295.8 58.8 3e-47 160.8 25.2 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KXG51957.1 - 4.9e-37 127.5 0.0 2.3e-17 63.8 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KXG51957.1 - 2e-30 104.5 1.8 3.1e-24 84.7 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KXG51957.1 - 2.3e-20 73.0 0.0 5.2e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KXG51957.1 - 0.00029 21.3 0.3 0.14 12.6 0.1 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 KXG51957.1 - 0.00033 21.2 0.0 0.0033 18.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXG51957.1 - 0.00043 20.2 0.1 0.027 14.4 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KXG51957.1 - 0.00052 19.6 0.1 0.0028 17.3 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KXG51957.1 - 0.00081 19.2 0.0 0.018 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXG51957.1 - 0.002 18.3 0.1 0.23 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXG51957.1 - 0.0034 17.2 0.1 3.8 7.2 0.0 2.7 2 1 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXG51957.1 - 0.015 15.0 0.9 1 9.1 0.2 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain SMC_N PF02463.19 KXG51957.1 - 0.019 14.4 0.0 1.4 8.3 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KXG51957.1 - 0.029 14.3 0.4 14 5.5 0.0 3.2 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.6 KXG51957.1 - 0.06 13.1 0.3 6.2 6.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KXG51957.1 - 0.08 13.4 0.1 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXG51957.1 - 0.081 13.2 0.2 9.5 6.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXG51957.1 - 0.11 12.6 0.1 34 4.6 0.1 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 KXG51957.1 - 0.23 10.5 52.3 0.0099 15.0 17.6 3.2 2 1 1 3 3 3 0 ABC-2 family transporter protein cobW PF02492.19 KXG51957.1 - 0.31 10.6 0.6 2.2 7.8 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arylsulfotran_2 PF14269.6 KXG51958.1 - 1.2e-75 254.7 1.4 1.9e-75 254.0 1.4 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXG51958.1 - 2.8e-15 56.1 0.3 1e-13 51.0 0.3 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MFS_1 PF07690.16 KXG51959.1 - 4e-43 147.7 43.4 4e-43 147.7 43.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG51959.1 - 4.5e-11 42.3 33.6 5.4e-11 42.0 16.9 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter GST_N_2 PF13409.6 KXG51960.1 - 2.8e-12 46.8 0.0 6.7e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXG51960.1 - 4.4e-11 43.0 0.0 1.2e-10 41.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXG51960.1 - 3.4e-09 36.9 0.0 6.4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXG51960.1 - 7.6e-07 29.3 0.0 1.9e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXG51960.1 - 0.00011 22.1 0.1 0.00035 20.5 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXG51960.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KXG51960.1 - 0.038 14.2 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin GST_C_5 PF16865.5 KXG51960.1 - 0.049 14.2 0.0 0.08 13.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Alpha-L-AF_C PF06964.12 KXG51961.1 - 2.6e-25 89.5 0.1 5.5e-25 88.4 0.1 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Patatin PF01734.22 KXG51962.1 - 3.2e-19 69.9 0.0 8.3e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.22 KXG51962.1 - 3.8e-12 45.9 0.0 6.7e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.6 KXG51962.1 - 6.7e-11 42.3 0.0 0.00026 21.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXG51962.1 - 1.4e-07 31.1 0.0 0.07 13.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat NACHT PF05729.12 KXG51962.1 - 2.6e-07 30.7 0.0 5.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXG51962.1 - 2.7e-06 27.7 0.0 8.5e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXG51962.1 - 0.029 14.7 0.0 0.15 12.4 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain TPR_MalT PF17874.1 KXG51962.1 - 0.087 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 MalT-like TPR region ATP-synt_ab PF00006.25 KXG51962.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SH3BGR PF04908.15 KXG51964.1 - 0.00021 21.4 0.0 0.00086 19.4 0.0 2.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Ribul_P_3_epim PF00834.19 KXG51965.1 - 2.3e-60 203.4 0.0 3.1e-59 199.7 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 KXG51965.1 - 0.078 12.3 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.24 KXG51965.1 - 0.081 12.5 0.1 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.19 KXG51965.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain bZIP_2 PF07716.15 KXG51966.1 - 0.62 10.2 8.6 2.1 8.5 3.0 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Methyltransf_11 PF08241.12 KXG51967.1 - 2.6e-08 34.4 0.0 5.5e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG51967.1 - 0.0019 18.9 0.0 0.005 17.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG51967.1 - 0.017 14.9 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.22 KXG51968.1 - 3.3e-17 61.9 0.6 4.5e-17 61.5 0.6 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXG51968.1 - 0.012 15.7 0.0 0.016 15.4 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain Hfq PF17209.3 KXG51968.1 - 0.018 14.7 0.1 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 Hfq protein LRR_9 PF14580.6 KXG51968.1 - 0.038 13.5 0.1 0.044 13.3 0.1 1.1 1 0 0 1 1 1 0 Leucine-rich repeat DRMBL PF07522.14 KXG51969.1 - 7.3e-34 116.3 0.0 1.3e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KXG51969.1 - 0.00026 20.6 0.0 0.00063 19.3 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Abhydrolase_6 PF12697.7 KXG51970.1 - 1.9e-10 41.7 0.0 3.1e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG51970.1 - 1.4e-09 38.0 0.1 2.1e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG51970.1 - 2.7e-06 26.8 0.1 4.8e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Pkinase PF00069.25 KXG51971.1 - 6.6e-17 61.7 0.0 1.7e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG51971.1 - 0.0001 21.7 0.0 0.0042 16.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase p450 PF00067.22 KXG51972.1 - 7.5e-103 344.7 0.0 8.9e-103 344.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OPT PF03169.15 KXG51973.1 - 1.5e-181 605.2 62.6 1.7e-181 605.0 62.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Gag_p10 PF02337.17 KXG51974.1 - 0.096 12.6 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 Retroviral GAG p10 protein SMP PF04927.12 KXG51975.1 - 1.9e-14 53.9 16.4 1.1e-05 25.8 4.2 3.2 3 0 0 3 3 3 3 Seed maturation protein Citrate_synt PF00285.21 KXG51976.1 - 3.2e-84 283.1 0.0 4e-84 282.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain GFA PF04828.14 KXG51976.1 - 2.8e-23 82.1 0.1 7.1e-23 80.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.16 KXG51977.1 - 8.1e-43 146.7 28.6 1.1e-42 146.2 28.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PBP PF01161.20 KXG51977.1 - 1.7e-12 47.8 0.0 3.2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein TRI12 PF06609.13 KXG51977.1 - 4.6e-05 22.0 3.0 0.0001 20.9 3.0 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KXG51977.1 - 0.0014 17.1 5.0 0.0014 17.1 5.0 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector Zn_clus PF00172.18 KXG51978.1 - 2.3e-08 34.0 5.6 5.8e-08 32.7 5.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP PF01161.20 KXG51979.1 - 9.2e-19 68.1 0.0 1.1e-18 67.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein NAD_binding_10 PF13460.6 KXG51980.1 - 9.6e-08 32.1 0.1 1.2e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXG51980.1 - 1.5e-07 31.2 0.1 4.2e-07 29.8 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 KXG51980.1 - 3.5e-07 29.9 0.1 9.1e-06 25.3 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXG51980.1 - 0.0016 17.5 0.0 0.0081 15.2 0.1 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXG51980.1 - 0.021 13.9 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ATG22 PF11700.8 KXG51981.1 - 2.3e-187 623.4 7.8 2.7e-187 623.2 7.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KXG51981.1 - 0.0011 18.0 21.9 0.0011 18.0 21.9 3.2 2 1 0 3 3 3 2 Major Facilitator Superfamily TMEM252 PF15664.5 KXG51981.1 - 0.04 13.6 0.2 0.078 12.7 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 252 family Sugar_tr PF00083.24 KXG51983.1 - 1.7e-76 257.9 28.7 2.1e-76 257.6 28.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG51983.1 - 2.2e-18 66.3 41.3 4e-18 65.5 33.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG51983.1 - 0.00036 19.5 4.7 0.00036 19.5 4.7 2.3 3 0 0 3 3 3 1 MFS_1 like family Romo1 PF10247.9 KXG51983.1 - 0.0054 17.1 1.3 0.025 15.0 1.3 2.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 DUF3493 PF11998.8 KXG51984.1 - 1.6 8.9 8.7 0.95 9.7 2.5 2.8 1 1 1 2 2 2 0 Low psii accumulation1 / Rep27 Dioxygenase_C PF00775.21 KXG51985.1 - 1.8e-09 37.3 0.1 3e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Dioxygenase SpaA PF17802.1 KXG51985.1 - 0.058 13.7 0.1 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 Prealbumin-like fold domain MFS_1 PF07690.16 KXG51986.1 - 2.3e-27 95.9 41.4 2.3e-26 92.6 35.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG51986.1 - 0.00012 20.7 3.7 0.00019 20.0 3.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KXG51986.1 - 7.8 4.6 9.5 3.4 5.9 0.0 2.8 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family adh_short_C2 PF13561.6 KXG51987.1 - 6.2e-63 212.5 0.4 7e-63 212.3 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG51987.1 - 1.8e-42 145.0 0.3 2.2e-42 144.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG51987.1 - 1.2e-16 61.1 0.2 1.6e-16 60.7 0.2 1.1 1 0 0 1 1 1 1 KR domain GH131_N PF18271.1 KXG51988.1 - 4.8e-63 213.2 0.2 5.4e-63 213.1 0.2 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 KXG51988.1 - 0.092 12.6 2.1 0.39 10.5 2.1 1.9 1 1 0 1 1 1 0 Polysaccharide lyase Sugar_tr PF00083.24 KXG51989.1 - 5.1e-96 322.3 25.0 5.9e-96 322.1 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG51989.1 - 1.3e-21 77.0 23.1 1.3e-21 77.0 23.1 1.7 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG51989.1 - 4.3e-05 22.1 0.7 9.1e-05 21.1 0.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Aa_trans PF01490.18 KXG51990.1 - 7.3e-38 130.3 36.1 7.3e-38 130.3 36.1 2.2 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein MFS_1 PF07690.16 KXG51990.1 - 6.3e-37 127.3 22.6 6.3e-37 127.3 22.6 3.4 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG51990.1 - 7.5e-15 54.7 10.7 7.5e-15 54.7 10.7 3.3 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KXG51990.1 - 0.00032 19.1 1.6 0.00032 19.1 1.6 3.3 4 1 0 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family DUF2963 PF11178.8 KXG51991.1 - 0.034 13.9 0.2 0.085 12.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) DUF1451 PF07295.11 KXG51991.1 - 0.15 12.1 1.7 3.7 7.6 0.5 2.1 1 1 1 2 2 2 0 Zinc-ribbon containing domain adh_short PF00106.25 KXG51992.1 - 3.8e-28 98.3 0.0 4.9e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG51992.1 - 1.8e-23 83.3 0.0 2.7e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG51992.1 - 3.2e-10 40.2 0.1 3.6e-09 36.8 0.1 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KXG51992.1 - 0.034 13.3 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UPRTase PF14681.6 KXG51995.1 - 7.4e-41 139.9 0.1 1.3e-40 139.0 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HAD PF12710.7 KXG51995.1 - 3.5e-15 56.9 0.0 5.7e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.6 KXG51995.1 - 2.3e-13 50.7 0.0 5.2e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXG51995.1 - 0.0011 19.1 0.0 0.0045 17.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain Pribosyltran PF00156.27 KXG51995.1 - 0.0014 18.1 0.6 0.024 14.2 0.6 2.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 KXG51995.1 - 0.015 14.8 0.1 0.032 13.7 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase Hydrolase_3 PF08282.12 KXG51995.1 - 0.055 13.2 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Peptidase_U4 PF03419.13 KXG51995.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA KAP_NTPase PF07693.14 KXG51995.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain Peptidase_M50B PF13398.6 KXG51996.1 - 3.8e-60 203.0 22.6 4.5e-60 202.7 22.6 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 KXG51996.1 - 0.012 14.9 1.0 0.014 14.7 0.3 1.5 1 1 0 1 1 1 0 Peptidase family M50 Peptidase_M41 PF01434.18 KXG51996.1 - 0.23 11.3 0.1 0.35 10.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M41 Patched PF02460.18 KXG51996.1 - 1.5 6.8 7.0 2.9 5.8 7.0 1.4 1 0 0 1 1 1 0 Patched family DUF2703 PF10865.8 KXG51997.1 - 0.024 14.8 0.8 1.2 9.3 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF2703) SWIRM-assoc_2 PF16496.5 KXG51997.1 - 1 8.2 8.2 1.7 7.5 8.2 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal SlyX PF04102.12 KXG51997.1 - 2.8 8.6 6.5 1.4 9.6 0.1 3.4 3 0 0 3 3 3 0 SlyX Endosulfine PF04667.17 KXG51998.1 - 5e-14 52.2 0.0 7.7e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Zea_mays_MuDR PF05928.11 KXG51999.1 - 0.011 15.4 0.6 0.017 14.8 0.6 1.2 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) NADH_u_ox_C PF12853.7 KXG51999.1 - 0.095 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Beta_elim_lyase PF01212.21 KXG52000.1 - 6e-69 232.5 0.0 7.5e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KXG52000.1 - 0.00032 19.4 0.0 0.00052 18.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 KXG52000.1 - 0.00093 18.0 0.1 0.0015 17.3 0.1 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Pkinase PF00069.25 KXG52001.1 - 8.8e-69 231.8 0.0 1.8e-68 230.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG52001.1 - 2.9e-32 112.0 0.0 4.9e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KXG52001.1 - 1e-10 41.8 0.5 2.2e-10 40.7 0.5 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXG52001.1 - 0.00013 22.2 0.1 0.0003 21.1 0.1 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 KXG52001.1 - 0.00055 19.9 0.2 0.56 10.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXG52001.1 - 0.0015 17.9 0.2 0.0027 17.1 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXG52001.1 - 0.0035 16.7 0.0 0.011 15.1 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXG52001.1 - 0.05 12.4 0.0 0.091 11.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KXG52001.1 - 0.079 12.6 0.3 0.16 11.5 0.3 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Glyco_transf_34 PF05637.12 KXG52002.1 - 1.2e-62 211.8 0.4 1.7e-62 211.3 0.4 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family NAD_binding_8 PF13450.6 KXG52003.1 - 3.5e-10 40.0 0.0 1.3e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXG52003.1 - 5.5e-09 35.6 0.0 3.6e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KXG52003.1 - 6.4e-09 34.8 0.0 2.5e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXG52003.1 - 1.3e-08 34.5 0.1 6.5e-06 25.6 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG52003.1 - 8e-07 28.6 0.0 0.33 10.1 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG52003.1 - 1.1e-06 28.5 0.1 1.1e-05 25.3 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KXG52003.1 - 0.0046 16.1 0.0 1.4 7.9 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.27 KXG52003.1 - 0.024 15.2 0.3 0.084 13.4 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG52003.1 - 0.03 14.3 0.0 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KXG52003.1 - 0.18 11.1 0.0 0.52 9.5 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KXG52003.1 - 0.19 10.9 0.1 0.36 10.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KXG52003.1 - 0.21 10.6 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Fungal_trans_2 PF11951.8 KXG52004.1 - 8.2e-13 47.9 0.1 1.3e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.12 KXG52005.1 - 7.8e-07 29.0 0.1 1.8e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG52005.1 - 1.5e-06 28.2 0.0 3.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG52005.1 - 4.8e-06 27.7 0.0 8.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KXG52005.1 - 0.00066 19.6 0.0 0.0018 18.1 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase EHN PF06441.12 KXG52006.1 - 2.1e-30 105.3 0.7 7.1e-30 103.6 0.4 2.0 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXG52006.1 - 1.1e-09 38.4 0.0 2.9e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG52006.1 - 0.017 15.7 7.9 0.055 14.1 5.0 2.8 2 1 0 2 2 2 0 Alpha/beta hydrolase family NDUFB10 PF10249.9 KXG52007.1 - 0.012 16.1 0.0 0.014 15.9 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 BRO1 PF03097.18 KXG52008.1 - 1.2e-08 34.2 0.0 2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Pkinase PF00069.25 KXG52009.1 - 0.0026 17.2 0.1 0.11 11.8 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain APH PF01636.23 KXG52009.1 - 0.0097 15.8 0.0 0.024 14.6 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Glyco_hydro_16 PF00722.21 KXG52011.1 - 1.3e-38 132.2 5.8 2.2e-38 131.5 5.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Bromo_TP PF07524.13 KXG52012.1 - 9e-06 25.6 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 KXG52012.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Uma2 PF05685.12 KXG52013.1 - 0.0002 21.0 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Putative restriction endonuclease TAFII55_N PF04658.13 KXG52014.1 - 3.6e-51 173.1 0.0 3.6e-51 173.1 0.0 2.1 3 0 0 3 3 3 1 TAFII55 protein conserved region DUF4407 PF14362.6 KXG52014.1 - 0.1 11.9 8.6 0.15 11.3 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MscS_porin PF12795.7 KXG52014.1 - 4.6 6.7 18.0 0.068 12.7 9.9 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Epimerase PF01370.21 KXG52016.1 - 1.8e-12 47.2 0.0 3.1e-12 46.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXG52016.1 - 2.5e-12 46.4 0.0 3.7e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXG52016.1 - 5.3e-11 42.7 0.0 7.7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXG52016.1 - 4.6e-08 32.5 0.1 9e-06 25.0 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KXG52016.1 - 1e-06 28.4 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXG52016.1 - 5.3e-06 26.2 0.0 3.2e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KXG52016.1 - 0.00031 20.0 0.0 0.00044 19.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXG52016.1 - 0.0049 16.0 0.0 0.0083 15.3 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.20 KXG52016.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus zf-Di19 PF05605.12 KXG52017.1 - 0.17 12.2 1.7 9.9 6.5 0.1 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding ADH_N PF08240.12 KXG52019.1 - 8.1e-24 83.6 0.2 1.6e-23 82.7 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG52019.1 - 8.8e-20 71.0 0.2 1.4e-19 70.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG52019.1 - 0.0014 19.7 0.0 0.0025 18.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MinC_N PF05209.13 KXG52019.1 - 0.0077 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Septum formation inhibitor MinC, N-terminal domain Guanylate_kin PF00625.21 KXG52020.1 - 3e-16 59.7 0.2 7.4e-16 58.4 0.0 1.6 2 0 0 2 2 2 1 Guanylate kinase HTH_32 PF13565.6 KXG52020.1 - 0.047 14.3 0.3 0.047 14.3 0.3 2.8 2 1 1 3 3 3 0 Homeodomain-like domain HTH_23 PF13384.6 KXG52020.1 - 0.09 12.6 2.1 0.099 12.5 0.2 2.1 2 0 0 2 2 2 0 Homeodomain-like domain ECH_1 PF00378.20 KXG52021.1 - 1.1e-21 77.2 0.0 1.3e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXG52021.1 - 1.1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KXG52021.1 - 0.09 12.7 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 DUF4291 PF14124.6 KXG52022.1 - 1.2e-70 237.1 0.1 1.4e-70 236.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Ofd1_CTDD PF10637.9 KXG52024.1 - 2.9e-98 328.3 0.0 1.5e-94 316.1 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KXG52024.1 - 1.3e-25 89.9 0.0 3e-25 88.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KXG52024.1 - 1e-13 52.0 0.0 2.1e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HLH PF00010.26 KXG52025.1 - 1.4e-14 53.7 0.2 4.5e-14 52.1 0.2 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Flagellin_N PF00669.20 KXG52025.1 - 0.28 11.3 4.5 0.84 9.7 0.3 2.4 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF4587 PF15248.6 KXG52025.1 - 0.8 10.5 9.7 3.9 8.3 0.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4587) Phosphodiest PF01663.22 KXG52028.1 - 9.1e-93 311.7 0.5 9.1e-93 311.7 0.5 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXG52028.1 - 1.4e-05 24.7 0.1 0.027 13.9 0.0 2.3 2 0 0 2 2 2 2 Sulfatase AP_endonuc_2 PF01261.24 KXG52028.1 - 0.19 11.2 0.4 6.9 6.1 0.0 2.9 3 0 0 3 3 3 0 Xylose isomerase-like TIM barrel Pex14_N PF04695.13 KXG52028.1 - 0.5 11.0 10.2 20 5.8 0.0 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.25 KXG52030.1 - 6.2e-49 166.7 0.0 7.5e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG52030.1 - 2.9e-28 98.9 0.0 3.6e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXG52030.1 - 9.6e-05 21.8 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXG52030.1 - 0.034 14.1 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 KXG52031.1 - 6.3e-59 194.6 23.5 2.3e-10 40.9 0.1 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG52031.1 - 1.5e-24 86.1 2.3 3e-05 24.2 0.0 6.6 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXG52031.1 - 7.4e-15 54.7 1.4 0.034 13.1 0.0 5.7 2 1 4 6 6 6 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXG52031.1 - 5.6e-11 42.1 0.1 2.2 8.3 0.0 7.0 7 0 0 7 7 7 3 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KXG52031.1 - 1.6e-07 31.4 0.7 0.11 12.3 1.0 4.0 1 1 4 5 5 5 3 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.9 KXG52031.1 - 1.7e-06 27.6 0.1 6.5 6.5 0.0 5.3 6 0 0 6 6 6 2 Proteasome subunit A N-terminal signature RAB3GAP2_N PF14655.6 KXG52031.1 - 6.5e-06 25.7 0.0 0.6 9.3 0.0 3.9 4 1 0 4 4 4 3 Rab3 GTPase-activating protein regulatory subunit N-terminus Nbas_N PF15492.6 KXG52031.1 - 6.6e-05 22.4 0.8 0.0078 15.6 0.0 3.4 1 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal DUF5122 PF17164.4 KXG52031.1 - 0.0022 18.3 1.5 20 5.6 0.1 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller DUF4596 PF15363.6 KXG52031.1 - 0.0033 17.6 5.3 5.3 7.3 0.1 5.1 5 0 0 5 5 5 1 Domain of unknown function (DUF4596) Nucleoporin_N PF08801.11 KXG52031.1 - 0.0083 14.9 0.0 2.3 6.9 0.0 2.9 2 2 0 2 2 2 1 Nup133 N terminal like DUF3748 PF12566.8 KXG52031.1 - 0.035 14.1 0.0 6 6.9 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3748) Nup160 PF11715.8 KXG52031.1 - 0.14 10.7 2.1 7.5 5.1 0.0 3.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 BCS1_N PF08740.11 KXG52032.1 - 2.1e-47 161.5 0.7 3.6e-47 160.8 0.7 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KXG52032.1 - 1.5e-18 67.5 0.0 6.9e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXG52032.1 - 0.0019 18.6 0.0 0.0044 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KXG52032.1 - 0.0044 17.6 0.0 0.016 15.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain YlbE PF14003.6 KXG52032.1 - 0.018 15.4 1.7 8.5 6.9 0.0 3.4 4 0 0 4 4 4 0 YlbE-like protein AAA_25 PF13481.6 KXG52032.1 - 0.032 13.8 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KXG52032.1 - 0.037 13.4 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 KXG52032.1 - 0.058 13.4 0.0 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KXG52032.1 - 0.13 11.4 0.0 0.33 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Glyco_hydro_43 PF04616.14 KXG52033.1 - 1.6e-33 116.2 0.0 2.3e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KXG52033.1 - 0.0053 16.4 0.0 0.1 12.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_130 PF04041.13 KXG52033.1 - 0.066 12.1 0.0 0.16 10.8 0.0 1.5 2 0 0 2 2 2 0 beta-1,4-mannooligosaccharide phosphorylase MFS_1 PF07690.16 KXG52034.1 - 5.9e-23 81.4 25.5 7.4e-23 81.0 25.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG52034.1 - 0.0002 20.4 1.7 0.0004 19.4 1.7 1.6 1 0 0 1 1 1 1 MFS_1 like family DUF3278 PF11683.8 KXG52034.1 - 0.031 14.3 1.3 3.1 7.9 0.1 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF3278) DUF308 PF03729.13 KXG52034.1 - 1.3 9.4 8.5 0.24 11.8 3.6 2.4 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DSBA PF01323.20 KXG52035.1 - 3.8e-05 23.6 0.0 4.2e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Caps_synth PF05704.12 KXG52036.1 - 3.3e-13 49.7 0.0 4.9e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KXG52036.1 - 1.6e-05 25.4 0.0 3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif HTH_Tnp_Tc5 PF03221.16 KXG52037.1 - 2.1e-05 24.4 0.0 3.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain PALP PF00291.25 KXG52038.1 - 1.1e-51 176.0 0.4 7.1e-50 170.1 0.4 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 KXG52038.1 - 0.073 12.9 0.4 0.49 10.2 0.3 2.1 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein GHMP_kinases_C PF08544.13 KXG52038.1 - 0.22 11.9 1.8 7 7.1 0.3 2.6 2 1 0 2 2 2 0 GHMP kinases C terminal TPMT PF05724.11 KXG52039.1 - 1.5e-32 113.0 0.0 2.2e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 KXG52039.1 - 9.9e-10 38.5 0.0 1.8e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cys_Met_Meta_PP PF01053.20 KXG52039.1 - 1.6e-08 33.5 0.0 2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Methyltransf_11 PF08241.12 KXG52039.1 - 1e-07 32.5 0.0 2.5e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG52039.1 - 1.8e-07 31.7 0.0 1.1e-06 29.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG52039.1 - 2.6e-06 28.1 0.0 9.8e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG52039.1 - 8.9e-06 25.6 0.0 4.9e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 KXG52039.1 - 0.095 11.9 0.1 0.41 9.8 0.0 1.9 1 1 1 2 2 2 0 N2227-like protein CheR PF01739.18 KXG52039.1 - 0.15 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain TehB PF03848.14 KXG52039.1 - 0.19 11.1 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB MFS_1 PF07690.16 KXG52040.1 - 6.1e-31 107.6 37.5 6.1e-31 107.6 37.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CLIP_SPH_mas PF18398.1 KXG52040.1 - 0.15 12.5 0.2 0.3 11.5 0.2 1.4 1 0 0 1 1 1 0 Clip-domain serine protease homolog masquerade DUF3533 PF12051.8 KXG52041.1 - 5.3e-98 328.4 14.8 6.8e-98 328.0 14.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) RibD_C PF01872.17 KXG52043.1 - 2.1e-32 112.6 0.0 2.4e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Fungal_trans_2 PF11951.8 KXG52044.1 - 1.6e-10 40.4 0.4 5.6e-10 38.6 0.0 1.9 1 1 2 3 3 3 1 Fungal specific transcription factor domain Patatin PF01734.22 KXG52045.1 - 6.5e-23 82.0 0.0 1.3e-22 81.0 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_12 PF13424.6 KXG52045.1 - 5.9e-18 64.9 0.1 4.2e-09 36.6 0.0 4.8 2 1 2 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 KXG52045.1 - 5e-11 42.3 0.1 1.1e-10 41.2 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain TPR_10 PF13374.6 KXG52045.1 - 7.3e-10 38.4 0.4 0.011 15.5 0.0 5.5 5 0 0 5 5 4 1 Tetratricopeptide repeat NACHT PF05729.12 KXG52045.1 - 1.3e-05 25.2 0.0 3.4e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXG52045.1 - 1.4e-05 25.4 0.0 5.8e-05 23.4 0.0 2.1 2 0 0 2 2 1 1 AAA domain TPR_7 PF13176.6 KXG52045.1 - 6e-05 22.8 0.0 0.032 14.3 0.0 3.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXG52045.1 - 0.00037 21.1 0.2 1.7 9.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 KXG52045.1 - 0.00045 20.5 0.4 0.26 11.6 0.1 4.0 1 1 3 4 4 4 1 Tetratricopeptide repeat AAA_16 PF13191.6 KXG52045.1 - 0.00048 20.5 0.1 0.002 18.5 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain TPR_19 PF14559.6 KXG52045.1 - 0.0006 20.3 2.6 6.4 7.4 0.1 4.5 2 1 3 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG52045.1 - 0.00064 19.9 1.0 0.21 11.8 0.1 4.2 2 1 3 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KXG52045.1 - 0.00095 19.7 2.8 22 6.0 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXG52045.1 - 0.0013 18.7 4.0 1.4 9.2 0.0 5.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXG52045.1 - 0.0054 17.4 0.1 5.3 8.1 0.0 5.0 4 1 2 6 6 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KXG52045.1 - 0.013 14.9 0.0 1.7 7.9 0.0 3.4 3 1 1 4 4 4 0 MalT-like TPR region IstB_IS21 PF01695.17 KXG52045.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3896 PF13035.6 KXG52045.1 - 0.068 13.3 0.3 4.1 7.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) TPR_8 PF13181.6 KXG52045.1 - 0.079 13.2 14.5 0.98 9.8 0.0 6.2 8 0 0 8 8 6 0 Tetratricopeptide repeat AAA PF00004.29 KXG52045.1 - 0.13 12.7 0.0 0.44 11.0 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Vps39_1 PF10366.9 KXG52045.1 - 0.17 12.1 1.7 1.3 9.3 0.3 3.2 2 1 0 2 2 1 0 Vacuolar sorting protein 39 domain 1 TPR_1 PF00515.28 KXG52045.1 - 0.78 9.7 7.7 3.6 7.6 0.0 4.7 6 0 0 6 6 4 0 Tetratricopeptide repeat Retrotran_gag_2 PF14223.6 KXG52047.1 - 3.2e-06 26.8 0.0 6.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type CFEM PF05730.11 KXG52048.1 - 0.02 15.0 11.0 0.02 15.0 11.0 2.5 2 1 0 2 2 2 0 CFEM domain Defensin_2 PF01097.18 KXG52048.1 - 0.047 13.6 0.4 0.047 13.6 0.4 2.2 2 0 0 2 2 2 0 Arthropod defensin Hamartin PF04388.12 KXG52048.1 - 2 7.0 13.0 2.6 6.6 13.0 1.1 1 0 0 1 1 1 0 Hamartin protein SPX PF03105.19 KXG52048.1 - 7.5 6.4 7.3 9.6 6.0 7.3 1.1 1 0 0 1 1 1 0 SPX domain MANEC PF07502.14 KXG52049.1 - 0.00017 21.8 10.5 0.038 14.3 3.7 2.5 2 0 0 2 2 2 2 MANEC domain PAN_4 PF14295.6 KXG52049.1 - 0.0013 18.5 19.0 0.071 13.0 1.1 3.0 2 1 0 2 2 2 2 PAN domain PAN_3 PF08277.12 KXG52049.1 - 3.8 7.4 18.9 0.84 9.5 9.6 3.5 3 2 0 3 3 3 0 PAN-like domain Glyco_hydro_11 PF00457.17 KXG52050.1 - 2.2e-75 252.2 19.5 2.6e-75 251.9 19.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Sulfate_transp PF00916.20 KXG52051.1 - 5.9e-108 361.0 17.2 8e-108 360.6 17.2 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXG52051.1 - 1e-07 31.6 0.0 2.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KXG52051.1 - 0.00013 22.4 3.5 0.00013 22.4 3.5 3.4 2 1 1 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 KXG52051.1 - 0.031 14.6 0.0 0.091 13.1 0.0 1.7 1 0 0 1 1 1 0 STAS domain Epiglycanin_C PF14654.6 KXG52051.1 - 0.12 12.5 0.2 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region SNN_transmemb PF09049.10 KXG52051.1 - 0.36 10.8 2.9 0.35 10.8 0.1 2.5 2 0 0 2 2 2 0 Stannin transmembrane Glyco_transf_90 PF05686.12 KXG52052.1 - 7.7e-31 107.4 0.0 1.1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KXG52052.1 - 0.0021 18.4 0.0 0.0036 17.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Kinesin PF00225.23 KXG52053.1 - 4.3e-111 371.1 0.0 6.7e-111 370.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 KXG52053.1 - 1.7e-44 152.2 0.2 5.3e-44 150.6 0.2 1.9 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 KXG52053.1 - 2.4e-37 128.9 8.7 1.1e-30 107.1 0.1 3.2 4 0 0 4 4 4 2 Kinesin-associated Microtub_bd PF16796.5 KXG52053.1 - 3.5e-24 85.4 0.0 1.1e-23 83.8 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 KXG52053.1 - 1.5e-07 31.7 0.1 5.8e-07 29.8 0.1 2.1 1 0 0 1 1 1 1 Kinesin protein 1B PH PF00169.29 KXG52053.1 - 4.3e-06 27.2 0.0 1.6e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 PH domain FHA PF00498.26 KXG52053.1 - 1.4e-05 25.3 0.0 0.00011 22.5 0.0 2.6 2 0 0 2 2 2 1 FHA domain UPF0242 PF06785.11 KXG52053.1 - 0.0013 18.9 9.4 0.34 11.0 5.2 2.6 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus MIF4G_like_2 PF09090.11 KXG52053.1 - 0.78 9.2 4.4 1.7 8.0 4.4 1.5 1 0 0 1 1 1 0 MIF4G like Ribosomal_S30AE PF02482.19 KXG52053.1 - 1.4 9.8 6.8 1 10.2 1.3 3.2 3 1 1 4 4 3 0 Sigma 54 modulation protein / S30EA ribosomal protein Atg14 PF10186.9 KXG52053.1 - 2.3 7.2 4.6 3 6.8 3.4 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HCMV_UL139 PF12507.8 KXG52054.1 - 0.0043 17.4 0.2 0.23 11.8 0.1 2.5 1 1 1 2 2 2 1 Human Cytomegalovirus UL139 protein LPP PF04728.13 KXG52054.1 - 0.044 14.2 0.2 17 5.9 0.1 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Baculo_PEP_C PF04513.12 KXG52054.1 - 0.062 13.3 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PLU-1 PF08429.11 KXG52054.1 - 0.099 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 PLU-1-like protein CBFB_NFYA PF02045.15 KXG52055.1 - 1.5e-28 99.1 4.6 3.1e-28 98.2 4.6 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.13 KXG52055.1 - 0.021 14.8 24.6 0.024 14.6 24.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hus1 PF04005.12 KXG52055.1 - 0.034 13.2 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein DUF3546 PF12066.8 KXG52057.1 - 1.9e-31 108.5 1.8 1.9e-31 108.5 1.8 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 KXG52057.1 - 1.4e-12 47.2 0.2 3.3e-12 46.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 KXG52057.1 - 1.2e-11 45.3 1.8 4.2e-11 43.6 0.2 2.7 1 1 1 2 2 2 1 Arsenite-resistance protein 2 bZIP_1 PF00170.21 KXG52059.1 - 9e-06 25.7 3.0 1.7e-05 24.8 3.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXG52059.1 - 0.031 14.3 6.3 0.063 13.4 6.3 1.5 1 0 0 1 1 1 0 Basic region leucine zipper zf-C2H2_aberr PF17017.5 KXG52059.1 - 0.15 12.2 0.3 0.29 11.3 0.3 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger eIF-3_zeta PF05091.12 KXG52060.1 - 6.3e-205 682.1 0.0 7.8e-205 681.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hydrophobin PF01185.18 KXG52061.1 - 2.1e-07 31.5 1.7 3e-07 31.0 1.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin cIII PF08134.11 KXG52061.1 - 0.032 14.0 0.1 0.056 13.2 0.1 1.3 1 0 0 1 1 1 0 cIII protein family Clathrin_bdg PF15045.6 KXG52061.1 - 0.064 13.3 0.1 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking NAD_binding_1 PF00175.21 KXG52062.1 - 3.4e-28 98.5 0.0 5.2e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXG52062.1 - 6.3e-20 71.4 0.0 9.7e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXG52062.1 - 1.4e-06 28.6 0.0 0.00014 22.0 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain adh_short PF00106.25 KXG52063.1 - 3.7e-20 72.2 0.0 4.9e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG52063.1 - 1.1e-15 57.8 0.0 1.5e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG52063.1 - 1.4e-06 28.4 0.0 1.8e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXG52063.1 - 0.00061 19.3 0.5 0.0025 17.3 0.1 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG52063.1 - 0.042 13.3 0.1 0.32 10.3 0.0 2.1 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXG52063.1 - 0.08 12.8 0.1 0.16 11.8 0.0 1.5 2 0 0 2 2 2 0 NAD(P)H-binding Cupin_1 PF00190.22 KXG52064.1 - 3e-38 130.8 0.1 7e-18 64.7 0.0 2.4 2 0 0 2 2 2 2 Cupin Ank_2 PF12796.7 KXG52064.1 - 2.1e-24 85.9 0.9 9.2e-17 61.4 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Cupin_2 PF07883.11 KXG52064.1 - 1.4e-22 79.1 0.8 7.8e-12 44.7 0.2 2.5 2 0 0 2 2 2 2 Cupin domain Ank_4 PF13637.6 KXG52064.1 - 4.3e-16 59.1 3.4 2.1e-08 34.5 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG52064.1 - 3.8e-15 54.5 3.2 0.0019 18.5 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KXG52064.1 - 4.1e-15 55.6 0.3 3.5e-06 27.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXG52064.1 - 2.3e-14 53.1 2.9 0.037 14.5 0.1 4.9 4 0 0 4 4 4 4 Ankyrin repeat AraC_binding PF02311.19 KXG52064.1 - 1.2e-07 31.7 0.0 0.00019 21.3 0.0 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 KXG52064.1 - 8.7e-06 25.4 0.1 0.12 12.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) bZIP_1 PF00170.21 KXG52064.1 - 0.0046 17.0 8.6 0.0078 16.3 8.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor MannoseP_isomer PF01050.18 KXG52064.1 - 0.0082 16.0 0.0 0.096 12.6 0.0 2.3 3 0 0 3 3 3 1 Mannose-6-phosphate isomerase bZIP_2 PF07716.15 KXG52064.1 - 0.011 15.7 6.3 0.021 14.9 6.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Cupin_6 PF12852.7 KXG52064.1 - 0.026 14.3 0.1 0.38 10.4 0.0 2.3 2 0 0 2 2 2 0 Cupin Cupin_4 PF08007.12 KXG52064.1 - 0.027 13.9 0.0 0.55 9.6 0.0 2.1 2 0 0 2 2 2 0 Cupin superfamily protein 3-HAO PF06052.12 KXG52064.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Pkinase_Tyr PF07714.17 KXG52065.1 - 7.7e-21 74.5 0.0 2.8e-20 72.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXG52065.1 - 6.2e-16 58.6 0.0 1.1e-15 57.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXG52065.1 - 0.0004 19.8 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXG52065.1 - 0.0049 16.2 0.0 0.17 11.1 0.0 2.1 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KXG52065.1 - 0.023 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Abhydro_lipase PF04083.16 KXG52069.1 - 9.7e-21 73.1 0.0 1.8e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KXG52069.1 - 8.9e-06 25.5 0.1 1.7e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KXG52069.1 - 0.043 12.7 0.0 0.25 10.2 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase enzyme MFS_1 PF07690.16 KXG52070.1 - 1.1e-39 136.4 60.0 5.8e-38 130.7 55.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FA_desaturase PF00487.24 KXG52072.1 - 2e-28 100.0 29.6 2.7e-28 99.5 29.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXG52072.1 - 0.0076 16.4 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_hydro_3 PF00933.21 KXG52073.1 - 2.8e-59 201.1 0.1 3.4e-59 200.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain TIR_2 PF13676.6 KXG52073.1 - 0.14 12.8 0.0 1.1 9.8 0.0 2.1 2 0 0 2 2 2 0 TIR domain Cation_efflux PF01545.21 KXG52074.1 - 1e-52 178.8 0.0 2.1e-52 177.7 0.0 1.5 1 1 0 1 1 1 1 Cation efflux family Zip PF02535.22 KXG52074.1 - 0.0042 16.4 5.1 0.2 10.8 2.4 2.3 2 0 0 2 2 2 2 ZIP Zinc transporter Fungal_lectin PF07938.12 KXG52075.1 - 1.8e-06 27.6 4.4 7e-06 25.6 3.4 2.5 1 1 0 1 1 1 1 Fungal fucose-specific lectin Glyco_transf_90 PF05686.12 KXG52076.1 - 1.5e-37 129.4 3.5 3.1e-37 128.4 3.5 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KXG52076.1 - 0.0013 19.1 0.6 0.0058 17.0 0.1 2.4 2 1 0 2 2 2 1 Glycosyl transferases group 1 DPM3 PF08285.11 KXG52076.1 - 0.0017 18.5 0.0 0.0035 17.5 0.0 1.5 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Metallophos PF00149.28 KXG52077.1 - 7.2e-09 36.4 0.0 3.3e-08 34.3 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.24 KXG52078.1 - 4.1e-126 421.5 25.2 4.6e-126 421.3 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG52078.1 - 2.8e-25 89.0 51.1 1.3e-21 76.9 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 KXG52078.1 - 0.0096 16.4 0.1 0.019 15.5 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat Ilm1 PF10311.9 KXG52078.1 - 0.1 12.3 0.5 0.19 11.3 0.5 1.4 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 MadM PF03818.13 KXG52078.1 - 5.6 6.9 8.1 5.6 6.9 0.5 3.7 3 0 0 3 3 3 0 Malonate/sodium symporter MadM subunit Lipase_GDSL_2 PF13472.6 KXG52079.1 - 3.1e-13 50.5 0.0 4e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXG52079.1 - 2.3e-10 40.8 0.0 2.6e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KXG52079.1 - 0.0029 17.8 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Nbl1_Borealin_N PF10444.9 KXG52079.1 - 0.017 14.7 0.4 0.37 10.5 0.1 2.2 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal zf-BED PF02892.15 KXG52080.1 - 0.62 10.1 6.8 16 5.6 2.1 3.5 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_4 PF13894.6 KXG52080.1 - 3.1 8.9 26.9 0.058 14.3 6.7 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger Aminotran_4 PF01063.19 KXG52081.1 - 1.5e-15 57.7 0.0 1.3e-08 35.0 0.1 2.2 1 1 1 2 2 2 2 Amino-transferase class IV S-methyl_trans PF02574.16 KXG52082.1 - 3.6e-40 138.5 0.0 4.1e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Glyco_transf_28 PF03033.20 KXG52083.1 - 1e-18 67.7 0.1 2.8e-13 50.1 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXG52083.1 - 1.1e-06 27.8 0.0 1.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KXG52083.1 - 1.9e-06 28.1 0.0 1.1e-05 25.7 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 KXG52083.1 - 0.00019 21.5 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF202 PF02656.15 KXG52085.1 - 3.9e-15 56.1 2.0 3.9e-15 56.1 2.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3372 PF11852.8 KXG52085.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) Methyltransf_25 PF13649.6 KXG52086.1 - 3.1e-18 66.3 0.0 5.7e-17 62.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG52086.1 - 5.9e-14 52.5 0.0 1.3e-13 51.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG52086.1 - 1.3e-13 51.5 0.0 2.9e-13 50.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG52086.1 - 6.7e-13 48.7 0.0 9e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG52086.1 - 3.6e-12 46.4 0.0 5.9e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXG52086.1 - 9.7e-09 35.0 0.0 1.5e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KXG52086.1 - 5.2e-06 26.0 0.0 1.1e-05 25.0 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 KXG52086.1 - 2.2e-05 23.6 0.0 3.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.11 KXG52086.1 - 0.00015 21.4 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.19 KXG52086.1 - 0.00024 21.0 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 KXG52086.1 - 0.00026 20.0 0.0 0.0005 19.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) DREV PF05219.12 KXG52086.1 - 0.0018 17.5 0.0 0.0029 16.7 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.20 KXG52086.1 - 0.0046 16.3 0.0 0.006 15.9 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KXG52086.1 - 0.0079 15.6 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KXG52086.1 - 0.019 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 KXG52086.1 - 0.027 14.0 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family MetW PF07021.12 KXG52086.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TehB PF03848.14 KXG52086.1 - 0.095 12.1 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB DHHC PF01529.20 KXG52087.1 - 0.014 15.5 3.0 0.019 15.1 3.0 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Pkinase PF00069.25 KXG52088.1 - 2e-69 233.9 0.0 3e-69 233.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG52088.1 - 1.2e-42 146.0 0.0 1.9e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KXG52088.1 - 3.1e-08 33.7 0.2 0.0045 17.1 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KXG52088.1 - 9.2e-07 28.4 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXG52088.1 - 0.056 12.4 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KXG52088.1 - 0.13 11.0 0.0 0.29 9.9 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase MFS_1 PF07690.16 KXG52089.1 - 1.7e-41 142.3 54.6 1.3e-40 139.4 55.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG52089.1 - 2.6e-23 82.3 21.3 3.4e-23 81.9 21.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXG52089.1 - 1e-15 57.6 9.0 1e-15 57.6 9.0 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KXG52089.1 - 0.34 9.1 15.9 0.05 11.9 2.3 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4337 PF14235.6 KXG52089.1 - 3.9 7.6 4.6 6.1 6.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Glyco_transf_28 PF03033.20 KXG52090.1 - 5.7e-21 75.0 0.1 3.2e-20 72.6 0.1 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXG52090.1 - 0.00066 18.6 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase zf-Tim10_DDP PF02953.15 KXG52090.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Tim10/DDP family zinc finger BBS1 PF14779.6 KXG52092.1 - 0.1 12.1 1.0 6.3 6.2 0.0 2.4 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 1 SKG6 PF08693.10 KXG52093.1 - 1.4e-05 24.4 1.0 1.4e-05 24.4 1.0 2.3 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Glycoprotein PF03409.15 KXG52093.1 - 0.0024 16.8 3.0 0.0034 16.3 3.0 1.3 1 0 0 1 1 1 1 Transmembrane glycoprotein Podoplanin PF05808.11 KXG52093.1 - 0.007 16.5 1.0 0.011 15.8 1.0 1.3 1 0 0 1 1 1 1 Podoplanin Mid2 PF04478.12 KXG52093.1 - 0.017 15.0 0.1 0.029 14.2 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Ank_4 PF13637.6 KXG52095.1 - 4.5e-65 215.2 25.3 2.4e-12 47.1 0.1 9.4 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXG52095.1 - 1.5e-55 185.7 18.3 9.4e-17 61.4 0.4 6.6 3 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 KXG52095.1 - 5e-46 153.2 33.5 7.5e-06 26.2 0.2 11.3 12 0 0 12 12 12 9 Ankyrin repeat Ank_3 PF13606.6 KXG52095.1 - 2.1e-40 132.1 8.7 0.0012 19.2 0.0 11.3 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 KXG52095.1 - 9.6e-38 127.8 14.5 1.2e-06 28.7 0.3 9.8 2 2 8 10 10 10 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXG52096.1 - 1.8e-17 63.7 0.1 1.5e-06 28.7 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG52096.1 - 6.9e-17 61.6 1.5 7.2e-06 26.5 0.0 4.9 3 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KXG52096.1 - 4.4e-16 58.5 2.8 3.5e-05 24.1 0.0 5.9 6 1 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 KXG52096.1 - 6.1e-16 56.9 0.3 0.00062 20.0 0.0 6.8 6 1 1 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KXG52096.1 - 8e-16 57.9 0.5 3.5e-09 36.8 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Acetyltransf_1 PF00583.25 KXG52099.1 - 1.8e-11 44.3 0.0 2.5e-11 43.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXG52099.1 - 1.3e-10 41.3 0.0 1.9e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXG52099.1 - 8.8e-10 38.9 0.0 1.3e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXG52099.1 - 2.9e-05 24.1 0.0 9.9e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG52099.1 - 0.0034 17.3 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXG52099.1 - 0.0045 17.1 0.0 0.0077 16.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase 2-Hacid_dh_C PF02826.19 KXG52100.1 - 3e-38 130.9 0.1 1.3e-24 86.6 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXG52100.1 - 0.00042 20.0 0.0 0.00067 19.3 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3HCDH_N PF02737.18 KXG52100.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXG52100.1 - 0.13 12.9 0.0 0.31 11.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1295 PF06966.12 KXG52101.1 - 1.4e-30 106.5 0.1 2e-30 106.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KXG52101.1 - 0.0014 18.6 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 KXG52101.1 - 0.0029 18.0 0.0 0.0078 16.6 0.0 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KXG52101.1 - 0.0033 17.8 0.6 0.0066 16.8 0.1 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KXG52101.1 - 0.01 14.6 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family LrgB PF04172.16 KXG52101.1 - 0.094 12.2 0.1 1.9 7.9 0.1 2.2 2 0 0 2 2 2 0 LrgB-like family HATPase_c_3 PF13589.6 KXG52102.1 - 1.8e-11 44.0 0.1 1.4e-10 41.1 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXG52102.1 - 6.4e-11 42.7 0.1 5.6e-10 39.7 0.1 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 KXG52102.1 - 1.7e-08 34.1 0.0 4.7e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain Glyco_hydro_36C PF16874.5 KXG52103.1 - 0.034 14.6 0.0 0.083 13.4 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 36 C-terminal domain AA_permease PF00324.21 KXG52104.1 - 7.6e-107 357.8 38.6 9.5e-107 357.5 38.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG52104.1 - 3.9e-26 91.9 42.9 8e-26 90.8 42.9 1.5 1 1 0 1 1 1 1 Amino acid permease SieB PF14163.6 KXG52104.1 - 7.6 6.0 6.7 6.7 6.2 4.6 2.0 1 1 0 1 1 1 0 Super-infection exclusion protein B OPA3 PF07047.12 KXG52105.1 - 3.1e-47 159.5 3.8 5.7e-47 158.6 3.8 1.5 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) BatD PF13584.6 KXG52105.1 - 0.0017 17.3 0.6 0.0025 16.7 0.6 1.2 1 0 0 1 1 1 1 Oxygen tolerance Ribosomal_L29 PF00831.23 KXG52105.1 - 0.4 10.7 4.6 0.33 11.0 1.0 2.5 2 0 0 2 2 2 0 Ribosomal L29 protein DUF4472 PF14739.6 KXG52105.1 - 1.5 9.6 7.0 1.1 10.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) Fez1 PF06818.15 KXG52105.1 - 1.6 9.1 6.5 12 6.3 0.1 2.1 2 0 0 2 2 2 0 Fez1 Myosin_head PF00063.21 KXG52107.1 - 6.2e-245 814.5 1.2 7.5e-245 814.3 1.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KXG52107.1 - 3.5e-54 183.3 0.0 6.8e-54 182.4 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KXG52107.1 - 1.7e-11 43.6 0.1 3.2e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXG52107.1 - 3.5e-07 29.8 0.0 9.8e-07 28.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KXG52107.1 - 5.9e-07 29.3 0.0 1.5e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 KXG52107.1 - 0.018 14.8 9.7 0.61 10.0 1.0 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_16 PF13191.6 KXG52107.1 - 0.022 15.1 0.0 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KXG52107.1 - 0.055 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXG52107.1 - 0.093 12.6 0.1 0.29 11.0 0.1 1.8 2 0 0 2 2 2 0 NACHT domain Hpr_kinase_C PF07475.12 KXG52107.1 - 0.098 12.2 0.7 8.3 5.9 0.1 2.8 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain PrcB_C PF14343.6 KXG52108.1 - 1.1 9.4 7.9 1.4 9.1 0.4 2.6 2 0 0 2 2 2 0 PrcB C-terminal WD40 PF00400.32 KXG52109.1 - 1.2e-05 26.0 2.0 0.00028 21.6 0.2 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF2415 PF10313.9 KXG52109.1 - 0.061 13.3 0.2 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) AMP-binding PF00501.28 KXG52110.1 - 6.8e-68 229.2 0.0 1.6e-67 228.0 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KXG52110.1 - 1.5e-58 198.0 0.0 2.4e-58 197.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KXG52110.1 - 8.5e-13 48.3 0.0 1.8e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 KXG52110.1 - 5.3e-12 46.5 0.2 3.8e-11 43.8 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KXG52110.1 - 4.3e-11 43.0 0.7 1.1e-10 41.7 0.7 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KXG52110.1 - 1.5e-08 34.0 0.0 1.2e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXG52110.1 - 8.4e-06 25.4 0.0 4.6e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KXG52110.1 - 0.0022 18.4 0.0 0.0045 17.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain SBBP PF06739.11 KXG52110.1 - 0.065 13.2 0.5 7.3 6.7 0.0 2.6 2 0 0 2 2 2 0 Beta-propeller repeat UDPG_MGDP_dh_C PF03720.15 KXG52110.1 - 0.16 12.4 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Aminotran_1_2 PF00155.21 KXG52111.1 - 1.5e-33 116.5 0.0 1.9e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 KXG52111.1 - 0.00066 18.5 0.0 0.053 12.3 0.0 2.1 2 0 0 2 2 2 2 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 KXG52111.1 - 0.066 11.7 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Chitin_synth_2 PF03142.15 KXG52112.1 - 3.9e-288 956.3 0.1 4.9e-288 956.0 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KXG52112.1 - 2.2e-11 44.1 5.3 7.6e-11 42.3 5.3 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXG52112.1 - 4.9e-08 33.1 0.0 2.9e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXG52112.1 - 0.00048 20.0 0.0 0.053 13.3 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KXG52112.1 - 0.0024 17.4 0.0 0.0072 15.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 21 Sel1 PF08238.12 KXG52113.1 - 3.2e-41 138.8 17.2 4.2e-07 30.4 0.0 7.4 7 0 0 7 7 7 7 Sel1 repeat Methyltransf_25 PF13649.6 KXG52114.1 - 1.7e-12 47.9 0.0 3.2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG52114.1 - 2e-10 41.3 0.0 3.7e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXG52114.1 - 9.3e-10 38.2 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KXG52114.1 - 1.6e-09 38.3 0.0 3.4e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG52114.1 - 5.3e-08 32.8 0.0 8.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG52114.1 - 9.3e-08 32.1 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXG52114.1 - 1.2e-06 28.2 0.0 2.9e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 KXG52114.1 - 2e-06 27.5 0.0 3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.7 KXG52114.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXG52114.1 - 0.0016 18.0 0.0 0.0062 16.0 0.0 1.9 2 1 1 3 3 3 1 Putative methyltransferase NodS PF05401.11 KXG52114.1 - 0.0028 17.3 0.0 0.0096 15.6 0.0 1.7 1 1 1 2 2 2 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 KXG52114.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KXG52114.1 - 0.043 13.6 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2855 PF11017.8 KXG52116.1 - 2.7e-93 313.4 0.2 3.2e-93 313.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Methyltransf_28 PF02636.17 KXG52116.1 - 0.12 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Arrestin_C PF02752.22 KXG52117.1 - 6.8e-07 29.8 0.0 1.4e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KXG52117.1 - 0.0015 18.6 0.2 0.055 13.5 0.0 2.7 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Fungal_trans PF04082.18 KXG52118.1 - 5e-08 32.3 0.2 1.5e-07 30.7 0.0 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain COesterase PF00135.28 KXG52119.1 - 1.3e-55 189.3 0.0 1.7e-55 188.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG52119.1 - 0.009 15.9 3.0 0.12 12.2 3.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold PARP PF00644.20 KXG52120.1 - 9.5e-58 195.0 0.5 4.4e-57 192.8 0.0 2.4 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KXG52120.1 - 6.2e-42 142.9 0.1 1.1e-41 142.2 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KXG52120.1 - 8e-20 70.7 0.7 2.4e-19 69.2 0.7 1.9 1 0 0 1 1 1 1 WGR domain PTCB-BRCT PF12738.7 KXG52120.1 - 1.5e-05 24.8 0.1 3.6e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KXG52120.1 - 0.00013 22.2 0.1 0.00039 20.7 0.1 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Roughex PF06020.11 KXG52120.1 - 0.15 11.1 14.2 1.3 8.0 0.2 2.2 2 0 0 2 2 2 0 Drosophila roughex protein PfkB PF00294.24 KXG52121.1 - 2.5e-40 138.7 1.8 2.9e-40 138.5 1.8 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Zn_clus PF00172.18 KXG52122.1 - 0.01 16.0 1.0 0.021 15.0 1.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KXG52123.1 - 4.3e-109 365.4 29.2 8.7e-109 364.4 29.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG52123.1 - 1.7e-21 76.5 61.2 8.1e-15 54.6 26.4 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 KXG52123.1 - 0.82 7.9 12.0 0.23 9.7 7.7 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans_2 PF11951.8 KXG52124.1 - 3.1e-11 42.7 0.2 6.1e-11 41.8 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_4 PF07993.12 KXG52125.1 - 3e-35 121.6 0.0 3.9e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KXG52125.1 - 1.1e-06 28.3 0.0 1.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ketoacyl-synt PF00109.26 KXG52126.1 - 7.8e-65 218.9 0.0 1.6e-64 217.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXG52126.1 - 9.1e-61 206.1 0.0 1.4e-60 205.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXG52126.1 - 4.2e-59 200.2 0.0 6.2e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KXG52126.1 - 7e-57 192.2 0.2 1.3e-56 191.4 0.2 1.4 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KXG52126.1 - 1e-26 93.3 0.2 2.5e-26 92.0 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXG52126.1 - 2.4e-26 92.4 0.0 1e-25 90.3 0.0 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KXG52126.1 - 9.6e-15 55.8 0.0 4.2e-14 53.7 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KXG52126.1 - 3.4e-12 46.5 0.0 9.6e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXG52126.1 - 1.5e-09 37.6 0.0 3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_12 PF08242.12 KXG52126.1 - 2.3e-09 37.9 0.0 1.4e-08 35.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KXG52126.1 - 2.1e-07 30.9 0.0 1.3e-06 28.4 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 KXG52126.1 - 3.4e-06 26.9 0.0 9.8e-05 22.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG52126.1 - 1.7e-05 25.3 0.0 4.9e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KXG52126.1 - 2.1e-05 24.2 0.0 8e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KXG52126.1 - 3e-05 23.5 0.1 6.1e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 KXG52126.1 - 5.5e-05 23.4 0.0 0.00024 21.4 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.12 KXG52126.1 - 0.00032 20.5 0.5 0.001 18.9 0.5 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_25 PF13649.6 KXG52126.1 - 0.00058 20.5 0.0 0.0029 18.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Lipocalin_5 PF13924.6 KXG52127.1 - 1e-36 125.9 0.1 1.1e-36 125.7 0.1 1.0 1 0 0 1 1 1 1 Lipocalin-like domain FA_hydroxylase PF04116.13 KXG52128.1 - 4.4e-26 91.8 17.7 4.4e-26 91.8 17.7 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Zip PF02535.22 KXG52129.1 - 1.3e-56 192.2 2.2 2.1e-56 191.6 2.2 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter bZIP_1 PF00170.21 KXG52130.1 - 9.5e-07 28.8 10.6 9.5e-07 28.8 10.6 3.7 2 1 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 KXG52130.1 - 2.9e-05 24.0 10.4 2.9e-05 24.0 10.4 4.2 2 1 1 4 4 4 1 Basic region leucine zipper BLOC1_2 PF10046.9 KXG52130.1 - 0.0065 16.7 6.0 0.0065 16.7 6.0 2.8 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 KXG52130.1 - 0.067 13.8 18.2 0.11 13.1 7.4 3.4 1 1 0 2 2 2 0 SlyX TBCA PF02970.16 KXG52130.1 - 0.13 12.6 11.6 0.34 11.3 11.6 1.9 1 0 0 1 1 1 0 Tubulin binding cofactor A UPF0242 PF06785.11 KXG52130.1 - 0.68 10.0 28.0 0.018 15.2 17.5 2.8 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_Maf PF03131.17 KXG52130.1 - 1.6 9.3 17.2 0.027 15.0 7.6 2.6 1 1 1 2 2 2 0 bZIP Maf transcription factor Tropomyosin_1 PF12718.7 KXG52130.1 - 3.2 7.9 21.8 6.9 6.8 14.8 2.7 1 1 1 2 2 2 0 Tropomyosin like DUF3450 PF11932.8 KXG52130.1 - 3.6 6.8 19.5 0.46 9.7 10.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 KXG52130.1 - 4.5 5.1 10.4 6.9 4.5 10.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF641 PF04859.12 KXG52130.1 - 7.8 6.8 16.8 0.16 12.3 9.3 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) zf-CCCH PF00642.24 KXG52131.1 - 4.9e-17 61.4 29.8 3.2e-05 23.7 1.3 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXG52131.1 - 3.5e-10 39.6 30.4 0.0063 16.5 0.8 6.1 5 1 0 5 5 5 4 Zinc finger domain zf-CCCH_3 PF15663.5 KXG52131.1 - 0.00043 20.5 17.5 0.0046 17.2 1.6 3.6 1 1 1 3 3 3 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KXG52131.1 - 0.0019 18.0 21.4 0.051 13.4 0.0 5.3 5 1 0 5 5 5 2 CCCH-type zinc finger zf-C3H1 PF10650.9 KXG52131.1 - 0.056 13.2 0.3 0.056 13.2 0.3 4.4 5 0 0 5 5 5 0 Putative zinc-finger domain Torus PF16131.5 KXG52131.1 - 0.066 13.9 29.8 0.26 12.0 0.8 4.7 2 1 3 5 5 5 0 Torus domain Ebp2 PF05890.12 KXG52131.1 - 0.097 12.2 4.2 0.17 11.4 4.2 1.3 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 TFIIF_beta_N PF17683.1 KXG52132.1 - 1.1e-29 103.8 0.1 2.2e-29 102.9 0.1 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 KXG52132.1 - 6.1e-28 96.7 0.3 1e-27 96.1 0.3 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 KXG52132.1 - 0.0031 18.3 0.5 0.0057 17.5 0.5 1.6 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain PCI PF01399.27 KXG52133.1 - 1.6e-12 47.8 0.0 3.9e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 KXG52133.1 - 2.9e-06 27.1 0.3 4.8e-06 26.4 0.3 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PspA_IM30 PF04012.12 KXG52133.1 - 0.0026 17.4 1.6 0.0051 16.4 1.6 1.4 1 0 0 1 1 1 1 PspA/IM30 family TPR_19 PF14559.6 KXG52133.1 - 0.018 15.5 2.0 0.56 10.8 0.4 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Herpes_UL14 PF03580.14 KXG52133.1 - 0.049 13.9 1.8 3.9 7.7 0.1 2.4 1 1 1 2 2 2 0 Herpesvirus UL14-like protein TPR_16 PF13432.6 KXG52133.1 - 0.32 11.7 5.2 2.4 8.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXG52133.1 - 2.7 9.0 7.1 26 6.0 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Aldedh PF00171.22 KXG52135.1 - 1.9e-136 455.3 2.5 2.3e-136 455.0 2.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HopA1 PF17914.1 KXG52135.1 - 0.028 14.2 0.0 7.8 6.2 0.0 2.3 2 0 0 2 2 2 0 HopA1 effector protein family DUF1487 PF07368.11 KXG52135.1 - 0.049 13.1 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) FAD_binding_2 PF00890.24 KXG52136.1 - 1.3e-85 288.0 0.8 1.6e-85 287.7 0.8 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KXG52136.1 - 1.6e-20 73.0 0.1 1.3e-19 70.0 0.0 2.6 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KXG52136.1 - 3.3e-15 56.5 0.2 6.5e-15 55.6 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG52136.1 - 1.1e-08 34.6 1.1 6e-07 29.0 0.8 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXG52136.1 - 6.5e-08 32.3 1.1 2.1e-07 30.7 1.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG52136.1 - 1.4e-07 31.6 1.9 5.1e-07 29.8 0.3 2.6 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXG52136.1 - 2.5e-07 29.8 0.8 0.0033 16.2 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 KXG52136.1 - 9.3e-07 28.4 0.1 0.0081 15.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXG52136.1 - 1.8e-05 24.2 0.2 2.8e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXG52136.1 - 2.8e-05 23.5 0.4 0.0085 15.4 0.1 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KXG52136.1 - 0.00049 19.3 2.7 0.18 10.8 0.8 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 KXG52136.1 - 0.0011 18.4 0.4 0.53 9.5 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KXG52136.1 - 0.0052 17.3 1.8 2.1 9.0 0.1 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXG52136.1 - 1 8.6 4.6 0.16 11.2 0.8 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain WD40 PF00400.32 KXG52138.1 - 5.1e-13 49.3 4.4 0.094 13.6 0.3 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG52138.1 - 0.012 15.9 0.2 3.6 7.9 0.0 3.8 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Sin3a_C PF16879.5 KXG52139.1 - 9.5e-77 258.5 6.5 9.5e-77 258.5 6.5 3.3 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 KXG52139.1 - 1.5e-41 140.3 3.0 1.3e-17 63.7 0.0 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KXG52139.1 - 6.7e-39 131.9 0.0 2.2e-38 130.3 0.0 2.0 1 0 0 1 1 1 1 Sin3 family co-repressor AcetylCoA_hydro PF02550.15 KXG52140.1 - 2.1e-48 164.9 0.0 3.2e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KXG52140.1 - 1.1e-39 135.8 0.0 2e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Glyco_hydro_17 PF00332.18 KXG52142.1 - 0.044 13.4 0.6 0.11 12.0 0.6 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 Glyco_hydro_11 PF00457.17 KXG52143.1 - 3.7e-54 183.0 2.7 4.4e-54 182.8 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Sugar_tr PF00083.24 KXG52144.1 - 6.4e-82 275.8 16.4 7.8e-82 275.5 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG52144.1 - 2.2e-21 76.2 18.0 2.2e-21 76.2 18.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF4926 PF16277.5 KXG52144.1 - 0.043 13.2 0.0 10 5.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4926) Kinocilin PF15033.6 KXG52144.1 - 0.15 11.7 0.4 0.39 10.4 0.4 1.7 1 0 0 1 1 1 0 Kinocilin protein Polyketide_cyc2 PF10604.9 KXG52146.1 - 0.00053 20.3 0.9 0.0015 18.9 0.7 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport CRISPR_assoc PF08798.11 KXG52146.1 - 0.084 13.0 0.1 0.14 12.3 0.1 1.5 1 1 0 1 1 1 0 CRISPR associated protein DHBP_synthase PF00926.19 KXG52147.1 - 1e-77 260.0 0.0 1.2e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase FlbD PF06289.11 KXG52147.1 - 0.039 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins Sugar_tr PF00083.24 KXG52148.1 - 1.4e-72 245.0 57.1 1.5e-72 244.9 22.8 3.1 2 1 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 KXG52148.1 - 5.3e-45 153.9 90.3 2.8e-19 69.3 26.4 4.0 1 1 3 4 4 4 4 Major Facilitator Superfamily Sel1 PF08238.12 KXG52149.1 - 4.2e-18 65.4 0.9 1.2e-05 25.8 0.5 4.3 5 0 0 5 5 5 3 Sel1 repeat TPR_6 PF13174.6 KXG52149.1 - 0.0048 17.5 0.4 1.7 9.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Mt_ATP-synt_B PF05405.14 KXG52150.1 - 3.1e-52 176.5 9.9 4.1e-52 176.1 9.9 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Taxilin PF09728.9 KXG52150.1 - 0.095 11.9 12.2 0.13 11.4 12.2 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF2526 PF10735.9 KXG52150.1 - 0.24 11.6 3.1 1 9.6 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2526) DUF932 PF06067.11 KXG52150.1 - 0.48 10.2 6.9 0.86 9.3 6.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF932) V_ATPase_I PF01496.19 KXG52150.1 - 1.6 6.6 8.2 2 6.2 8.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hrs_helical PF12210.8 KXG52150.1 - 6.1 7.4 11.0 1.7 9.3 3.2 2.5 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate CBF PF03914.17 KXG52151.1 - 5.6e-37 127.4 2.4 8.8e-37 126.7 0.4 2.2 3 0 0 3 3 3 1 CBF/Mak21 family DPPIV_rep PF18811.1 KXG52151.1 - 0.089 12.8 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) low complexity region GPI-anchored PF10342.9 KXG52152.1 - 1.5e-15 57.7 0.1 1.5e-15 57.7 0.1 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 KXG52152.1 - 0.42 9.8 12.4 0.5 9.5 12.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SHE3 PF17078.5 KXG52153.1 - 4.4e-06 26.6 32.0 0.0002 21.2 25.2 2.3 1 1 1 2 2 2 2 SWI5-dependent HO expression protein 3 ADIP PF11559.8 KXG52153.1 - 0.021 14.9 16.9 0.021 14.9 16.9 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4061 PF13270.6 KXG52153.1 - 0.022 15.1 1.8 0.022 15.1 1.8 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) HALZ PF02183.18 KXG52153.1 - 0.023 14.9 6.5 0.042 14.1 4.2 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper ZapB PF06005.12 KXG52153.1 - 0.038 14.4 8.9 0.038 14.4 8.9 3.7 2 2 1 3 3 3 0 Cell division protein ZapB DUF3037 PF11236.8 KXG52153.1 - 2.3 8.7 8.0 2 8.8 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) Ank_4 PF13637.6 KXG52155.1 - 7.8e-54 179.4 10.1 5.7e-11 42.7 0.0 7.6 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXG52155.1 - 2.6e-45 152.9 18.0 9.4e-13 48.6 0.3 5.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG52155.1 - 1.2e-23 80.6 8.8 0.042 14.4 0.0 9.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KXG52155.1 - 6.6e-23 80.5 23.8 0.00086 19.6 0.1 10.3 3 2 7 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 KXG52155.1 - 2.6e-21 75.0 31.1 0.0041 17.5 0.3 10.7 11 0 0 11 11 11 6 Ankyrin repeat NACHT PF05729.12 KXG52155.1 - 5.6e-08 32.9 0.7 1.1e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KXG52155.1 - 0.00018 21.8 0.6 0.0012 19.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXG52155.1 - 0.00034 21.0 0.8 0.0023 18.3 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 KXG52155.1 - 0.0059 17.0 0.0 8.1 6.9 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Goodbye PF17109.5 KXG52155.1 - 0.0084 16.6 0.4 0.029 14.8 0.4 2.0 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain NB-ARC PF00931.22 KXG52155.1 - 0.063 12.4 0.1 0.43 9.7 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain MMS19_C PF12460.8 KXG52156.1 - 6.9e-125 417.5 18.0 1.1e-122 410.2 9.3 3.8 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 KXG52156.1 - 3.1e-96 322.0 1.2 4.3e-93 311.7 0.0 3.4 4 0 0 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 KXG52156.1 - 5.4e-06 26.7 4.0 1.4 9.3 0.3 5.9 6 0 0 6 6 6 2 HEAT repeats RTP1_C1 PF10363.9 KXG52156.1 - 3.6e-05 23.9 6.1 0.11 12.7 0.0 4.6 5 0 0 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KXG52156.1 - 0.028 14.9 14.1 6.2 7.4 1.4 5.9 5 0 0 5 5 5 0 HEAT-like repeat Arm PF00514.23 KXG52156.1 - 0.037 14.1 4.0 1.4 9.0 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat WAPL PF07814.13 KXG52156.1 - 0.041 12.7 1.3 0.12 11.2 0.4 2.3 2 1 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin HEAT PF02985.22 KXG52156.1 - 0.2 12.0 15.2 52 4.5 0.3 8.0 9 0 0 9 9 9 0 HEAT repeat Fasciclin PF02469.22 KXG52157.1 - 2.1e-07 31.2 0.0 3.7e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain EMC3_TMCO1 PF01956.16 KXG52158.1 - 2.6e-53 180.2 1.5 3.4e-53 179.9 1.5 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF4405 PF14358.6 KXG52158.1 - 6.4 7.4 7.7 12 6.5 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) SPC25 PF06703.11 KXG52159.1 - 4.6e-50 169.6 0.1 5.3e-50 169.4 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) THF_DHG_CYH PF00763.23 KXG52160.1 - 1.1e-25 90.1 0.1 1.8e-25 89.5 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KXG52160.1 - 3.8e-12 45.8 0.1 2.5e-10 39.9 0.1 2.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP-synt_ab PF00006.25 KXG52161.1 - 1.6e-71 240.4 0.0 2.3e-71 239.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KXG52161.1 - 6.1e-48 162.3 0.5 1e-47 161.6 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KXG52161.1 - 9.9e-15 54.8 3.2 2.4e-14 53.6 3.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RbcS PF12338.8 KXG52161.1 - 6.9 6.9 9.2 1.8 8.8 0.3 2.7 2 0 0 2 2 2 0 Ribulose-1,5-bisphosphate carboxylase small subunit DUF962 PF06127.11 KXG52162.1 - 1.6e-26 92.2 1.4 2.2e-26 91.8 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.17 KXG52163.1 - 2.3e-13 50.3 0.0 4.9e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KXG52163.1 - 3.6e-09 36.8 0.0 6.7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Jnk-SapK_ap_N PF09744.9 KXG52163.1 - 1.6 9.0 7.5 0.78 10.0 0.9 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Piwi PF02171.17 KXG52164.1 - 3.2e-74 249.9 0.0 5.4e-74 249.1 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KXG52164.1 - 1.2e-18 68.1 0.0 2e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 KXG52164.1 - 2e-12 47.2 0.0 6.7e-12 45.6 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoL1 PF08699.10 KXG52164.1 - 3.1e-10 39.6 0.3 1.3e-09 37.6 0.2 2.1 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 KXG52164.1 - 3.7e-10 39.8 0.0 8.6e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KXG52164.1 - 6.5e-06 26.3 0.0 1.5e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute p450 PF00067.22 KXG52165.1 - 2.9e-66 224.1 0.0 3.8e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KXG52166.1 - 5.6e-10 38.7 0.0 1.2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG52166.1 - 1e-06 28.7 13.0 1.7e-06 28.0 13.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 KXG52166.1 - 0.062 13.2 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 RRM_1 PF00076.22 KXG52167.1 - 7.2e-36 121.8 0.0 2.1e-17 62.7 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXG52167.1 - 0.003 17.6 0.1 1.8 8.7 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif RRM_8 PF11835.8 KXG52167.1 - 0.011 15.9 0.0 0.03 14.5 0.0 1.7 2 0 0 2 2 2 0 RRM-like domain SET_assoc PF11767.8 KXG52167.1 - 0.1 12.3 0.0 0.32 10.7 0.0 1.8 1 1 0 1 1 1 0 Histone lysine methyltransferase SET associated DUF3539 PF12058.8 KXG52167.1 - 0.16 12.2 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3539) DUF3445 PF11927.8 KXG52168.1 - 3.4e-76 255.8 0.0 4.1e-76 255.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) AA_permease_2 PF13520.6 KXG52169.1 - 3.3e-40 138.2 49.6 4.1e-40 137.9 49.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG52169.1 - 1.7e-25 89.6 46.3 2.2e-25 89.2 46.3 1.0 1 0 0 1 1 1 1 Amino acid permease Na_K-ATPase PF00287.18 KXG52169.1 - 0.38 9.9 2.0 0.59 9.3 2.0 1.2 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain GMC_oxred_N PF00732.19 KXG52170.1 - 2.9e-75 253.4 0.0 4e-75 252.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG52170.1 - 9.2e-35 120.3 0.4 1.4e-33 116.5 0.4 2.2 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXG52170.1 - 4.8e-06 25.9 0.0 0.0023 17.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KXG52170.1 - 0.00098 18.3 0.1 0.0016 17.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KXG52170.1 - 0.0054 16.4 1.0 0.034 13.7 0.5 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXG52170.1 - 0.055 12.7 0.2 0.49 9.6 0.1 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 KXG52170.1 - 0.17 11.1 0.0 0.54 9.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ribonuc_L-PSP PF01042.21 KXG52171.1 - 6e-20 71.5 0.0 6.9e-20 71.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP SLAC1 PF03595.17 KXG52172.1 - 1.3e-70 238.3 46.1 1.4e-70 238.1 46.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Adeno_E3 PF06040.11 KXG52172.1 - 0.044 14.0 1.9 3.3 7.9 0.0 2.7 3 0 0 3 3 3 0 Adenovirus E3 protein DUF5527 PF17665.1 KXG52172.1 - 0.35 10.4 2.4 9.3 5.8 0.4 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5527) Aldedh PF00171.22 KXG52173.1 - 1.8e-175 583.9 0.3 2e-175 583.7 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPR_2 PF07719.17 KXG52174.1 - 2e-22 77.4 2.9 1.5e-07 31.0 0.1 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXG52174.1 - 2.2e-22 77.9 3.0 2.4e-08 33.5 0.1 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KXG52174.1 - 1.5e-18 66.2 3.4 4.4e-09 35.9 0.1 5.1 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.6 KXG52174.1 - 2.8e-18 66.3 3.1 1e-05 26.1 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXG52174.1 - 9.4e-17 60.3 1.8 6.8e-05 23.4 0.0 5.9 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXG52174.1 - 4.9e-15 55.8 3.2 0.0004 20.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXG52174.1 - 7.6e-14 51.0 1.7 0.0065 16.8 0.1 5.0 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXG52174.1 - 1.4e-13 49.9 0.7 2.3e-06 27.4 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXG52174.1 - 3.4e-11 42.4 1.4 0.0058 16.6 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 KXG52174.1 - 3.5e-11 43.3 0.5 0.0056 17.0 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXG52174.1 - 1e-09 38.4 2.0 0.0016 18.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXG52174.1 - 5e-09 36.3 7.6 3.9e-06 27.0 1.2 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG52174.1 - 5.1e-06 26.6 2.2 0.00031 20.9 0.3 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KXG52174.1 - 1.4e-05 25.4 1.6 1.1 10.1 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXG52174.1 - 8.5e-05 21.9 0.8 0.25 10.5 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.12 KXG52174.1 - 0.00031 20.7 0.1 0.13 12.3 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat MIT PF04212.18 KXG52174.1 - 0.00059 19.9 0.3 4.2 7.5 0.1 4.2 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KXG52174.1 - 0.0037 17.1 4.3 0.054 13.4 0.9 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF1641 PF07849.11 KXG52174.1 - 0.06 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TOM20_plant PF06552.12 KXG52174.1 - 0.097 12.4 0.1 3.4 7.4 0.0 3.0 3 1 1 4 4 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF4192 PF13830.6 KXG52174.1 - 0.35 10.9 6.6 2.2 8.2 6.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) DUF1269 PF06897.12 KXG52174.1 - 0.41 11.0 1.6 0.91 9.8 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) NSF PF02071.20 KXG52174.1 - 9.1 7.6 5.5 1.1e+02 4.3 0.3 3.8 3 0 0 3 3 2 0 Aromatic-di-Alanine (AdAR) repeat HCO3_cotransp PF00955.21 KXG52175.1 - 5.1e-68 230.1 10.9 2.7e-38 132.1 4.9 2.1 1 1 1 2 2 2 2 HCO3- transporter family Methyltransf_28 PF02636.17 KXG52178.1 - 7.4e-40 137.2 0.0 1.1e-39 136.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KXG52178.1 - 0.17 11.8 0.0 0.34 10.7 0.0 1.5 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PRT_C PF08372.10 KXG52178.1 - 0.47 10.2 2.7 0.35 10.6 0.6 1.8 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal PALP PF00291.25 KXG52179.1 - 5.2e-59 200.1 0.5 6.9e-59 199.7 0.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme BDV_P10 PF06515.11 KXG52179.1 - 0.073 13.1 0.1 9.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Borna disease virus P10 protein Scm3 PF10384.9 KXG52180.1 - 1.7e-20 72.5 0.0 4e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 APG6 PF04111.12 KXG52181.1 - 6.8e-72 241.2 0.0 9.9e-72 240.6 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KXG52181.1 - 1.6e-39 135.5 5.1 2.5e-39 134.9 5.1 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Snapin_Pallidin PF14712.6 KXG52181.1 - 0.19 12.1 2.2 0.33 11.4 0.3 2.1 2 0 0 2 2 2 0 Snapin/Pallidin CENP-F_leu_zip PF10473.9 KXG52181.1 - 0.22 11.5 4.6 0.42 10.6 4.6 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 KXG52181.1 - 3.5 7.7 6.9 4.6 7.3 5.3 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AflR PF08493.10 KXG52182.1 - 6.4 6.2 18.5 0.32 10.4 5.3 2.1 2 0 0 2 2 2 0 Aflatoxin regulatory protein Peroxin-13_N PF04088.13 KXG52183.1 - 1.1e-52 178.2 0.1 1.6e-52 177.7 0.1 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KXG52183.1 - 2.5e-09 36.7 0.0 4.5e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXG52183.1 - 6e-08 32.2 0.0 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXG52183.1 - 2.3e-05 24.2 0.1 3.8e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 KXG52183.1 - 0.21 12.0 0.0 0.37 11.2 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain DUF726 PF05277.12 KXG52184.1 - 3.5 6.5 6.1 5.2 5.9 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) ERO1 PF04137.15 KXG52185.1 - 4.5e-135 450.4 0.0 6e-135 450.0 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) KGG PF10685.9 KXG52188.1 - 2.7e-21 75.1 17.5 1.4e-09 37.9 0.7 3.2 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif adh_short PF00106.25 KXG52189.1 - 5.1e-45 153.3 1.0 9.2e-45 152.5 1.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG52189.1 - 2.2e-42 145.2 0.3 4.9e-42 144.1 0.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG52189.1 - 6.4e-10 39.2 2.5 5e-09 36.3 2.5 2.1 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KXG52189.1 - 0.00027 20.9 0.0 0.00048 20.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 KXG52189.1 - 0.0013 18.2 0.1 0.021 14.3 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXG52189.1 - 0.0025 17.3 0.2 0.011 15.3 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXG52189.1 - 0.0047 16.3 0.8 0.01 15.2 0.8 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KXG52189.1 - 0.0053 15.9 0.1 0.01 15.0 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KXG52189.1 - 0.039 14.0 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Dak1 PF02733.17 KXG52189.1 - 0.057 12.3 0.1 2.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Dak1 domain DUF4334 PF14232.6 KXG52190.1 - 2.7e-22 78.5 0.8 4.7e-22 77.7 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4334) GXWXG PF14231.6 KXG52190.1 - 5.7e-22 77.6 0.4 1.1e-21 76.7 0.4 1.4 1 0 0 1 1 1 1 GXWXG protein SDA1 PF05285.12 KXG52191.1 - 0.051 13.0 6.2 0.094 12.1 6.2 1.4 1 0 0 1 1 1 0 SDA1 Med26 PF08711.11 KXG52191.1 - 0.055 13.5 1.0 0.35 10.9 0.0 2.5 2 0 0 2 2 2 0 TFIIS helical bundle-like domain CDC45 PF02724.14 KXG52191.1 - 0.67 8.2 5.9 1.2 7.4 5.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_23 PF13489.6 KXG52192.1 - 1e-08 35.2 0.0 1.8e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG52192.1 - 8.4e-07 29.6 0.0 2.9e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG52192.1 - 1.7e-06 28.7 0.0 3.3e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG52192.1 - 0.00014 21.7 0.0 0.00078 19.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG52192.1 - 0.00033 21.2 0.0 0.00088 19.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Isochorismatase PF00857.20 KXG52193.1 - 1.4e-29 103.5 0.0 2.6e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family Iso_dh PF00180.20 KXG52193.1 - 8.8e-14 51.4 0.0 1.4e-12 47.4 0.0 2.1 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Methyltransf_25 PF13649.6 KXG52194.1 - 3.2e-09 37.4 0.0 6.1e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG52194.1 - 3.9e-05 23.5 0.0 5.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG52194.1 - 5.8e-05 23.0 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG52194.1 - 8e-05 23.2 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG52194.1 - 0.00028 21.5 0.0 0.00044 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG52194.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Abhydrolase_6 PF12697.7 KXG52195.1 - 4.5e-10 40.5 0.2 6.5e-10 40.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LapA_dom PF06305.11 KXG52196.1 - 3.6 7.5 6.8 8 6.4 2.0 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain GMC_oxred_C PF05199.13 KXG52197.1 - 3.5e-32 111.9 0.0 5.4e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KXG52197.1 - 1e-27 97.3 0.0 3.4e-24 85.8 0.0 3.0 1 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 KXG52197.1 - 0.0015 18.7 0.0 0.0042 17.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG52197.1 - 0.011 15.0 0.0 0.034 13.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG52197.1 - 0.021 13.9 0.1 0.032 13.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KXG52197.1 - 0.15 11.3 0.2 4.4 6.5 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXG52197.1 - 0.2 11.3 0.1 0.39 10.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hyd_65N_2 PF14498.6 KXG52199.1 - 7.2e-38 130.8 0.0 1.5e-37 129.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain FAD_binding_3 PF01494.19 KXG52201.1 - 1e-21 77.6 0.3 5.8e-10 39.0 0.0 2.8 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KXG52201.1 - 8.4e-05 22.0 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG52201.1 - 0.058 13.0 1.6 1 8.9 0.3 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG52201.1 - 0.09 13.0 0.1 0.56 10.5 0.3 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG52201.1 - 0.21 10.8 0.8 3.4 6.8 0.8 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG52201.1 - 0.82 10.3 2.3 1.7 9.3 0.2 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PAF-AH_p_II PF03403.13 KXG52202.1 - 3.9e-13 48.7 0.0 9.2e-07 27.7 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KXG52202.1 - 7.2e-06 25.1 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KXG52202.1 - 4.2e-05 22.9 0.1 0.0033 16.7 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXG52202.1 - 0.007 17.0 1.4 0.011 16.3 1.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KXG52202.1 - 0.17 10.9 2.2 4.8 6.1 2.2 2.1 1 1 0 1 1 1 0 Chlorophyllase LIP PF03583.14 KXG52202.1 - 0.21 10.9 0.3 0.35 10.2 0.3 1.3 1 0 0 1 1 1 0 Secretory lipase Fungal_trans_2 PF11951.8 KXG52203.1 - 2.8e-17 62.6 0.1 1.6e-16 60.1 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain OPT PF03169.15 KXG52204.1 - 2.4e-163 545.1 52.3 2.7e-163 544.9 52.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein p450 PF00067.22 KXG52205.1 - 2.9e-65 220.8 0.0 3.6e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NACHT PF05729.12 KXG52206.1 - 7.2e-10 39.0 0.6 1.1e-08 35.1 0.1 3.2 4 0 0 4 4 4 1 NACHT domain AAA_16 PF13191.6 KXG52206.1 - 1.6e-09 38.4 0.0 1.9e-08 34.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain SesA PF17107.5 KXG52206.1 - 0.0057 16.8 0.1 0.098 12.8 0.0 3.1 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 KXG52206.1 - 0.01 16.1 0.0 0.042 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXG52206.1 - 0.015 15.7 0.0 0.045 14.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase CHAD PF05235.14 KXG52206.1 - 0.017 15.1 1.9 0.055 13.4 0.1 2.3 2 0 0 2 2 2 0 CHAD domain AAA_23 PF13476.6 KXG52206.1 - 0.028 14.9 3.2 0.33 11.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXG52206.1 - 0.028 14.9 1.5 0.31 11.5 0.0 2.7 2 0 0 2 2 2 0 ABC transporter ORC4_C PF14629.6 KXG52206.1 - 0.032 13.6 2.3 5.3 6.3 0.0 2.7 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 4 C-terminus AAA_29 PF13555.6 KXG52206.1 - 0.048 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KXG52206.1 - 0.065 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KXG52206.1 - 0.11 12.2 0.1 0.51 10.0 0.0 2.1 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KXG52206.1 - 0.18 12.3 0.0 1 9.8 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 KXG52206.1 - 0.27 11.3 1.2 1.7 8.7 0.0 2.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 KXG52206.1 - 0.35 11.4 1.5 0.86 10.1 0.2 2.4 2 1 0 2 2 2 0 AAA domain NmrA PF05368.13 KXG52207.1 - 1.2e-30 106.8 0.0 1.4e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG52207.1 - 1.1e-08 35.2 0.0 1.8e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXG52207.1 - 0.00022 21.5 0.0 0.00042 20.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXG52207.1 - 0.0019 17.7 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KXG52208.1 - 4.1e-38 130.8 0.3 5.5e-38 130.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG52208.1 - 8.9e-27 94.1 0.6 1.2e-26 93.8 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KXG52208.1 - 3.6e-06 26.6 0.0 5.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KXG52208.1 - 0.0027 17.2 0.1 0.011 15.2 0.1 1.9 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KXG52208.1 - 0.062 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 KXG52209.1 - 4.4e-21 75.6 0.1 6.1e-21 75.1 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXG52209.1 - 7.2e-20 71.5 0.0 8.9e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXG52209.1 - 4e-05 23.2 0.1 7.5e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1134 PF06577.12 KXG52209.1 - 0.0027 17.5 0.0 0.0083 15.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1134) ADH_zinc_N PF00107.26 KXG52209.1 - 0.012 15.6 0.0 0.037 14.0 0.1 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase 3Beta_HSD PF01073.19 KXG52209.1 - 0.045 12.8 0.0 0.23 10.4 0.1 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXG52209.1 - 0.15 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXG52209.1 - 0.15 11.5 0.3 0.35 10.3 0.2 1.6 1 1 1 2 2 2 0 short chain dehydrogenase Transglut_core PF01841.19 KXG52209.1 - 0.2 12.2 0.6 0.6 10.6 0.1 2.0 1 1 1 2 2 2 0 Transglutaminase-like superfamily Sid-5 PF17204.3 KXG52210.1 - 0.13 12.4 0.3 3.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Sid-5 family MARVEL PF01284.23 KXG52210.1 - 1.2 9.1 9.2 0.18 11.8 0.6 3.0 4 0 0 4 4 4 0 Membrane-associating domain MFS_1 PF07690.16 KXG52211.1 - 3.5e-33 115.0 49.9 1.3e-32 113.1 49.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG52211.1 - 1.7e-12 46.6 27.2 3.6e-12 45.5 27.2 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXG52211.1 - 1.1e-11 44.3 10.9 1.1e-11 44.3 10.9 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3522 PF12036.8 KXG52211.1 - 0.0059 16.9 0.3 0.0059 16.9 0.3 3.5 1 1 3 4 4 4 1 Protein of unknown function (DUF3522) DUF3937 PF13073.6 KXG52211.1 - 0.5 10.5 4.3 0.21 11.7 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3937) OATP PF03137.20 KXG52211.1 - 4.4 5.5 27.2 3.3 5.9 10.7 3.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family NHS PF15273.6 KXG52212.1 - 0.1 11.7 8.6 0.1 11.7 8.6 1.0 1 0 0 1 1 1 0 NHS-like DUF1849 PF08904.11 KXG52212.1 - 0.11 12.1 1.9 0.13 11.7 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) AbiEii PF08843.11 KXG52214.1 - 2.8e-05 24.2 0.0 5.5e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system DUF2204 PF09970.9 KXG52214.1 - 0.083 12.5 0.1 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 Nucleotidyl transferase of unknown function (DUF2204) Terpene_synth_C PF03936.16 KXG52215.1 - 0.00029 20.3 0.0 0.0004 19.8 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain SIP1 PF04938.12 KXG52215.1 - 0.18 11.5 0.0 0.26 11.0 0.0 1.5 1 1 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Helo_like_N PF17111.5 KXG52216.1 - 9.6e-06 25.1 0.3 1.9e-05 24.1 0.3 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF3659 PF12396.8 KXG52217.1 - 9.6e-171 553.9 95.1 1.7e-21 75.9 5.0 9.5 9 0 0 9 9 9 9 Protein of unknown function (DUF3659) ApoO PF09769.9 KXG52217.1 - 0.095 12.7 1.8 6.3 6.8 0.1 2.9 2 1 1 3 3 3 0 Apolipoprotein O CDP-OH_P_transf PF01066.21 KXG52218.1 - 9.6e-15 55.1 0.2 9.6e-15 55.1 0.2 3.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_M1_N PF17900.1 KXG52219.1 - 0.00026 21.2 0.0 0.29 11.3 0.0 2.4 1 1 1 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 KXG52219.1 - 0.093 12.3 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M1 domain LSM PF01423.22 KXG52220.1 - 4.9e-22 77.4 0.1 5.4e-22 77.3 0.1 1.0 1 0 0 1 1 1 1 LSM domain eIF-3c_N PF05470.12 KXG52220.1 - 0.16 10.3 0.0 0.18 10.1 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus MCR_C PF04609.12 KXG52221.1 - 0.63 9.1 3.2 0.73 8.9 0.5 1.9 1 1 1 2 2 2 0 Methyl-coenzyme M reductase operon protein C PT PF04886.12 KXG52222.1 - 1.8 8.2 13.6 8.2 6.1 13.6 2.2 1 0 0 1 1 1 0 PT repeat 2-Hacid_dh_C PF02826.19 KXG52225.1 - 6.8e-40 136.3 0.3 9.9e-40 135.8 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXG52225.1 - 2.4e-09 37.0 0.0 4.9e-09 35.9 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Cadherin_tail PF15974.5 KXG52225.1 - 0.04 14.2 0.0 0.066 13.6 0.0 1.3 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region F420_oxidored PF03807.17 KXG52225.1 - 0.068 13.8 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Gp_dh_N PF00044.24 KXG52225.1 - 0.17 12.3 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain zf-LITAF-like PF10601.9 KXG52226.1 - 1.3e-15 57.4 18.8 1.9e-15 56.9 18.8 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain ATP_transf PF09830.9 KXG52227.1 - 2.1e-22 79.0 0.0 5.1e-22 77.8 0.0 1.7 1 0 0 1 1 1 1 ATP adenylyltransferase GalP_UDP_transf PF01087.22 KXG52227.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain zf-C2H2 PF00096.26 KXG52228.1 - 0.00032 21.0 18.8 0.47 11.0 1.1 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type BssC_TutF PF08201.11 KXG52228.1 - 0.074 13.1 0.4 0.27 11.2 0.4 2.0 1 0 0 1 1 1 0 BssC/TutF protein FOXP-CC PF16159.5 KXG52228.1 - 0.58 10.8 3.5 18 6.1 0.5 3.3 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KXG52228.1 - 1.2 10.2 20.5 0.69 10.9 0.7 5.0 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXG52228.1 - 5.6 7.4 7.3 19 5.7 0.6 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Glyco_hydro_20 PF00728.22 KXG52229.1 - 1.3e-102 343.8 2.8 1.6e-102 343.5 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KXG52229.1 - 3.5e-25 89.2 0.0 7.4e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KXG52229.1 - 0.00026 21.8 0.0 0.00053 20.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DHDPS PF00701.22 KXG52230.1 - 1.7e-51 174.6 0.0 2.1e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family SAS4 PF15460.6 KXG52231.1 - 8.5e-31 106.0 5.4 2.3e-30 104.6 5.4 1.7 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Aa_trans PF01490.18 KXG52232.1 - 4e-41 141.1 38.0 4.8e-41 140.8 38.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3188 PF11384.8 KXG52232.1 - 1.9 8.2 7.1 2 8.2 1.8 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) DUF3807 PF12720.7 KXG52233.1 - 1e-34 120.4 16.1 5.1e-34 118.1 16.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3807) CDC45 PF02724.14 KXG52233.1 - 3.8 5.7 7.2 4 5.6 7.2 1.0 1 0 0 1 1 1 0 CDC45-like protein HVSL PF09749.9 KXG52234.1 - 3.9e-83 278.6 0.1 4.5e-83 278.4 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein 4HBT_3 PF13622.6 KXG52235.1 - 5.2e-43 148.1 0.0 5.9e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KXG52235.1 - 0.028 14.3 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA thioesterase OTT_1508_deam PF14441.6 KXG52236.1 - 4.8e-19 68.1 0.2 1.1e-18 67.0 0.2 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Chol_subst-bind PF09129.11 KXG52236.1 - 0.14 11.1 0.0 0.37 9.7 0.0 1.6 1 1 0 1 1 1 0 Cholesterol oxidase, substrate-binding SesA PF17107.5 KXG52237.1 - 5.9e-05 23.3 0.1 7.9e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 KXG52237.1 - 0.013 14.9 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Apolipoprotein PF01442.18 KXG52238.1 - 0.0038 17.1 17.7 3.6 7.4 12.5 3.6 3 1 0 3 3 3 1 Apolipoprotein A1/A4/E domain DUF5610 PF18433.1 KXG52238.1 - 0.028 14.9 2.3 0.12 12.9 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF5610) MHCassoc_trimer PF08831.10 KXG52238.1 - 0.063 13.3 0.3 2.9 8.0 0.1 3.0 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain DUF2524 PF10732.9 KXG52238.1 - 0.26 11.6 7.0 6.8 7.1 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2524) DUF2115 PF09888.9 KXG52238.1 - 0.55 10.7 7.3 1.9 9.0 0.0 3.5 2 1 1 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2115) YtxH PF12732.7 KXG52238.1 - 0.58 10.7 32.2 2.6 8.6 3.4 6.0 2 1 1 3 3 3 0 YtxH-like protein DUF883 PF05957.13 KXG52238.1 - 2.4 8.8 13.5 69 4.1 0.0 5.6 4 1 2 6 6 6 0 Bacterial protein of unknown function (DUF883) DUF2232 PF09991.9 KXG52238.1 - 3.8 6.6 4.5 46 3.1 0.1 3.2 4 0 0 4 4 4 0 Predicted membrane protein (DUF2232) TssO PF17561.2 KXG52238.1 - 4.7 7.3 13.3 0.35 11.0 0.5 3.4 3 1 0 3 3 3 0 Type VI secretion system, TssO ApoL PF05461.11 KXG52238.1 - 6.7 5.9 9.1 0.32 10.3 0.9 2.6 3 0 0 3 3 3 0 Apolipoprotein L Pal1 PF08316.11 KXG52240.1 - 1e-09 39.3 0.2 1.6e-09 38.7 0.2 1.4 1 0 0 1 1 1 1 Pal1 cell morphology protein Peptidase_S10 PF00450.22 KXG52241.1 - 1.2e-77 262.2 0.1 1.7e-77 261.6 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Ferritin_2 PF13668.6 KXG52242.1 - 4.7e-10 39.8 0.1 6.3e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF3568 PF12092.8 KXG52242.1 - 0.013 15.6 0.6 0.025 14.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Glyco_hydro_3_C PF01915.22 KXG52243.1 - 2.7e-56 190.8 0.1 4.4e-56 190.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXG52243.1 - 5.8e-41 140.9 0.0 9.4e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXG52243.1 - 7.9e-28 96.4 0.1 1.5e-27 95.5 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Fungal_trans PF04082.18 KXG52244.1 - 8.7e-14 51.2 0.1 1.4e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG52244.1 - 4e-06 26.8 9.8 1e-05 25.5 9.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPE65 PF03055.15 KXG52245.1 - 2.6e-86 290.7 0.1 3.9e-49 168.1 0.2 2.0 1 1 1 2 2 2 2 Retinal pigment epithelial membrane protein FMO-like PF00743.19 KXG52246.1 - 1e-15 57.2 0.1 1.3e-11 43.7 0.1 3.1 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXG52246.1 - 7.4e-12 45.3 0.0 2.3e-11 43.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXG52246.1 - 5.3e-10 39.4 2.2 0.017 14.7 0.1 3.4 2 1 1 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG52246.1 - 1e-08 34.8 0.0 2.6e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG52246.1 - 7.8e-07 28.6 0.1 7.5e-05 22.1 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG52246.1 - 1.4e-06 27.7 0.1 0.00076 18.7 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KXG52246.1 - 0.0012 18.1 1.8 0.014 14.6 0.1 3.1 4 0 0 4 4 4 1 Thi4 family NAD_binding_9 PF13454.6 KXG52246.1 - 0.0035 17.3 0.3 0.71 9.8 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXG52246.1 - 0.0068 16.9 0.1 2.1 8.9 0.4 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KXG52246.1 - 0.01 14.4 0.3 0.29 9.6 0.1 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) LAT2 PF15703.5 KXG52246.1 - 0.14 12.1 0.3 0.23 11.3 0.3 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells family member 2 AlaDh_PNT_C PF01262.21 KXG52246.1 - 0.91 8.8 2.4 3.4 6.9 0.1 2.6 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Sugar_tr PF00083.24 KXG52247.1 - 1.1e-62 212.4 25.8 1.3e-62 212.2 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG52247.1 - 7.6e-11 41.5 27.2 7.6e-11 41.5 27.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.23 KXG52248.1 - 6.5e-28 97.2 0.1 1.8e-27 95.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain FAD-oxidase_C PF02913.19 KXG52248.1 - 3.7e-13 49.7 0.3 1.7e-12 47.5 0.7 1.8 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain MJ1316 PF04457.12 KXG52248.1 - 0.017 15.8 0.1 0.055 14.2 0.1 1.9 1 0 0 1 1 1 0 MJ1316 RNA cyclic group end recognition domain p450 PF00067.22 KXG52249.1 - 1.4e-63 215.3 0.0 1.8e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 XK-related PF09815.9 KXG52249.1 - 0.06 12.4 0.2 0.09 11.8 0.2 1.2 1 0 0 1 1 1 0 XK-related protein Ank_4 PF13637.6 KXG52251.1 - 0.00035 21.1 0.1 0.00078 20.0 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG52251.1 - 0.0017 18.7 0.0 0.12 13.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KXG52251.1 - 0.0032 17.7 0.1 0.01 16.1 0.0 1.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXG52251.1 - 0.0077 16.8 0.0 0.015 15.9 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXG52251.1 - 0.014 15.8 0.0 1 9.9 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat HeLo PF14479.6 KXG52252.1 - 2e-06 27.8 0.0 2.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation Metallophos PF00149.28 KXG52253.1 - 2.1e-09 38.2 0.5 3e-09 37.7 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Vac14_Fab1_bd PF12755.7 KXG52253.1 - 0.16 12.6 0.0 0.34 11.5 0.0 1.5 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region MFS_1 PF07690.16 KXG52254.1 - 5.9e-11 41.9 33.6 5.9e-11 41.9 33.6 3.8 2 2 1 3 3 3 2 Major Facilitator Superfamily DUF997 PF06196.12 KXG52254.1 - 0.28 11.2 4.0 8.8 6.4 0.2 3.8 2 0 0 2 2 2 0 Protein of unknown function (DUF997) IQCJ-SCHIP1 PF15157.6 KXG52255.1 - 1.8 8.4 4.3 8.9 6.1 0.1 2.1 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif ELFV_dehydrog PF00208.21 KXG52256.1 - 6.7e-84 281.4 4.9 8.4e-84 281.1 4.9 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KXG52256.1 - 1.9e-51 173.3 0.0 3.7e-51 172.4 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Med5 PF08689.10 KXG52257.1 - 7.8e-180 600.2 0.0 1.5e-179 599.3 0.0 1.4 1 1 0 1 1 1 1 Mediator complex subunit Med5 ABC2_membrane PF01061.24 KXG52258.1 - 1.3e-79 266.5 48.7 2.1e-44 151.4 16.2 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KXG52258.1 - 6.6e-39 133.6 0.0 2.4e-18 67.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXG52258.1 - 1.2e-29 102.0 8.9 7.6e-28 96.3 0.1 3.6 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KXG52258.1 - 1.6e-06 27.5 34.6 0.00042 19.5 12.1 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KXG52258.1 - 3.7e-06 27.4 0.1 0.0044 17.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KXG52258.1 - 0.00014 21.5 0.1 0.0032 17.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXG52258.1 - 0.00015 22.0 0.2 0.76 10.0 0.1 2.8 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXG52258.1 - 0.00041 20.3 0.0 0.0035 17.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 KXG52258.1 - 0.00063 20.0 0.1 0.77 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXG52258.1 - 0.0012 19.4 0.0 4.9 7.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KXG52258.1 - 0.0014 18.4 1.0 0.091 12.5 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KXG52258.1 - 0.0024 18.0 0.7 0.95 9.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 KXG52258.1 - 0.0033 17.0 0.6 1.3 8.6 0.1 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ABC_trans_N PF14510.6 KXG52258.1 - 0.015 15.9 0.0 0.048 14.3 0.0 1.8 1 0 0 1 1 1 0 ABC-transporter N-terminal NACHT PF05729.12 KXG52258.1 - 0.034 14.0 0.3 2.7 7.9 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 KXG52258.1 - 0.079 12.7 0.3 7.1 6.3 0.3 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KXG52258.1 - 0.087 12.6 0.6 9.2 6.0 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 KXG52258.1 - 0.15 11.3 0.3 4.2 6.6 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin dNK PF01712.19 KXG52258.1 - 0.29 10.9 0.9 30 4.4 0.0 3.3 4 0 0 4 4 4 0 Deoxynucleoside kinase Halogen_Hydrol PF10112.9 KXG52258.1 - 1.2 9.1 3.7 25 4.8 2.0 2.7 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein RasGEF PF00617.19 KXG52259.1 - 8.8e-51 172.6 1.1 1.9e-50 171.5 1.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXG52259.1 - 1e-14 54.7 0.0 2.7e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 KXG52259.1 - 1.8e-06 27.7 0.0 4e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXG52259.1 - 1.7e-05 24.4 0.0 3.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain MutL_C PF08676.11 KXG52260.1 - 6.8e-06 25.9 0.0 0.00024 20.9 0.0 2.9 2 1 0 2 2 2 1 MutL C terminal dimerisation domain MCM_bind PF09739.9 KXG52261.1 - 0.22 9.9 0.6 0.41 9.0 0.6 1.4 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor p450 PF00067.22 KXG52262.1 - 5.7e-42 144.0 0.0 7.7e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 bZIP_2 PF07716.15 KXG52264.1 - 8.4e-14 51.4 12.1 2e-13 50.2 12.1 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KXG52264.1 - 0.0031 17.6 9.0 0.0031 17.6 9.0 2.2 1 1 1 2 2 2 1 bZIP transcription factor DUF5343 PF17278.2 KXG52264.1 - 0.022 14.9 1.3 0.15 12.1 1.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5343) DDRGK PF09756.9 KXG52264.1 - 0.055 13.1 12.2 0.11 12.1 12.2 1.4 1 0 0 1 1 1 0 DDRGK domain CBP_BcsG PF11658.8 KXG52264.1 - 1.1 7.5 6.1 0.14 10.5 2.0 1.5 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG NAM-associated PF14303.6 KXG52264.1 - 4.5 8.0 13.5 1.5 9.5 10.0 1.9 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain MFS_1 PF07690.16 KXG52266.1 - 9.5e-40 136.6 42.6 9.5e-40 136.6 42.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG52266.1 - 2.9e-11 42.9 8.2 2.9e-11 42.9 8.2 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter NAD_binding_8 PF13450.6 KXG52267.1 - 7e-17 61.4 0.0 3.1e-16 59.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXG52267.1 - 1.6e-10 40.9 0.1 1.3e-06 28.0 0.1 3.0 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 KXG52267.1 - 0.00066 19.4 0.0 0.0025 17.4 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXG52267.1 - 0.0034 17.4 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXG52267.1 - 0.027 13.6 0.0 0.083 12.0 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KXG52267.1 - 0.031 13.5 0.0 0.19 10.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXG52267.1 - 0.1 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 KXG52267.1 - 0.1 13.2 0.1 0.33 11.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CENP-N PF05238.13 KXG52268.1 - 3.9e-138 461.2 0.0 4.4e-138 461.1 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like DUF974 PF06159.13 KXG52269.1 - 5.6e-78 262.1 0.0 6.7e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) PhaC_N PF07167.13 KXG52269.1 - 0.002 17.8 0.2 0.022 14.4 0.0 2.3 2 1 0 2 2 2 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus DENN PF02141.21 KXG52270.1 - 3.8e-57 193.3 0.2 6.3e-57 192.5 0.2 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KXG52270.1 - 2.1e-13 50.8 0.0 4.6e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KXG52270.1 - 3.5e-13 49.3 0.9 1.5e-12 47.3 0.7 2.2 2 0 0 2 2 2 1 dDENN domain SPA PF08616.10 KXG52270.1 - 0.038 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis DHquinase_I PF01487.15 KXG52271.1 - 8.5e-46 157.0 0.0 1.2e-45 156.6 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase FMN_bind_2 PF04299.12 KXG52272.1 - 1.2e-50 171.5 0.0 8.7e-50 168.7 0.0 1.9 1 1 0 1 1 1 1 Putative FMN-binding domain Fungal_trans PF04082.18 KXG52273.1 - 1.2e-19 70.4 0.0 2.5e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG52273.1 - 0.00021 21.3 17.2 0.00021 21.3 17.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.19 KXG52274.1 - 5.2e-45 153.0 0.0 8e-45 152.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXG52274.1 - 0.0012 18.6 0.0 0.0018 17.9 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ELFV_dehydrog PF00208.21 KXG52274.1 - 0.0019 17.9 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AdoHcyase_NAD PF00670.21 KXG52274.1 - 0.0078 16.3 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 KXG52274.1 - 0.01 16.4 0.0 0.033 14.7 0.0 1.7 2 0 0 2 2 2 0 XdhC Rossmann domain Pyr_redox PF00070.27 KXG52274.1 - 0.091 13.3 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cu_amine_oxid PF01179.20 KXG52275.1 - 5.4e-156 519.6 0.0 7.2e-156 519.2 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KXG52275.1 - 9.3e-17 61.3 0.0 2.6e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KXG52275.1 - 2.7e-13 50.0 0.0 4.7e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF4105 PF13387.6 KXG52275.1 - 0.12 12.0 0.1 0.4 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4105) Aldedh PF00171.22 KXG52276.1 - 5.9e-181 602.0 0.3 6.7e-181 601.8 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXG52276.1 - 0.14 11.6 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) AA_permease_2 PF13520.6 KXG52278.1 - 1.5e-53 182.1 50.8 1.8e-53 181.9 50.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG52278.1 - 4.9e-19 68.3 38.9 6.8e-19 67.8 38.9 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1182 PF06681.13 KXG52278.1 - 0.13 11.9 5.5 0.17 11.4 4.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1182) Rhabdo_ncap PF00945.18 KXG52279.1 - 0.2 10.5 4.9 0.32 9.8 4.9 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Peptidase_M20 PF01546.28 KXG52280.1 - 2e-21 76.7 0.0 3.6e-21 75.8 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXG52280.1 - 5.4e-14 52.0 0.0 2.8e-13 49.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain GATase PF00117.28 KXG52281.1 - 0.0042 16.9 0.0 0.0063 16.3 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KXG52281.1 - 0.0072 16.2 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 SNO glutamine amidotransferase family ThiJ_like PF17124.5 KXG52281.1 - 0.078 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like RhaA PF06134.11 KXG52281.1 - 0.19 10.8 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 L-rhamnose isomerase (RhaA) TRAM_LAG1_CLN8 PF03798.16 KXG52282.1 - 7.8e-36 123.7 19.0 7.8e-36 123.7 19.0 1.7 3 0 0 3 3 3 1 TLC domain TRAM1 PF08390.11 KXG52282.1 - 3e-23 81.2 0.1 8.1e-23 79.9 0.1 1.8 1 0 0 1 1 1 1 TRAM1-like protein BRO1 PF03097.18 KXG52283.1 - 7.3e-121 403.6 0.0 1.6e-120 402.5 0.0 1.6 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KXG52283.1 - 2.5e-84 283.1 6.0 4.4e-84 282.3 6.0 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DRE2_N PF16803.5 KXG52283.1 - 0.15 12.3 0.0 2.8 8.2 0.0 2.7 2 0 0 2 2 2 0 Fe-S cluster assembly protein DRE2 N-terminus AA_permease_2 PF13520.6 KXG52284.1 - 4.7e-45 154.2 54.2 5.6e-45 153.9 54.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG52284.1 - 1e-19 70.5 44.9 1.4e-19 70.1 44.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1035 PF06281.12 KXG52284.1 - 0.11 12.6 4.2 0.46 10.5 4.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1035) Cation_ATPase_C PF00689.21 KXG52285.1 - 3.4 7.3 12.2 9 6.0 12.2 1.7 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus Mito_carr PF00153.27 KXG52286.1 - 6.4e-42 141.4 4.2 1.7e-15 56.7 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Thiolase_N PF00108.23 KXG52287.1 - 1.8e-15 57.1 0.0 5.3e-15 55.5 0.0 1.8 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXG52287.1 - 2e-12 46.8 0.7 3.6e-11 42.8 0.7 2.4 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KXG52287.1 - 1.5e-06 28.0 0.4 9.1e-05 22.2 0.0 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 KXG52287.1 - 0.0053 15.5 0.2 0.025 13.3 0.1 2.0 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 KXG52287.1 - 0.011 15.4 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Peptidase_S49 PF01343.18 KXG52287.1 - 0.014 15.3 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 DUF3431 PF11913.8 KXG52288.1 - 2.2e-68 230.2 0.0 2.8e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) SMN PF06003.12 KXG52290.1 - 1e-07 31.5 6.0 7.8e-06 25.3 0.3 2.4 1 1 0 2 2 2 2 Survival motor neuron protein (SMN) RRM_1 PF00076.22 KXG52291.1 - 4.3e-13 48.9 0.0 8.7e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXG52291.1 - 0.013 15.4 0.3 0.18 11.8 0.2 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RL PF17797.1 KXG52291.1 - 0.053 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 RL domain CHD5 PF04420.14 KXG52292.1 - 3.1e-62 209.2 4.4 3.8e-62 208.8 4.4 1.1 1 0 0 1 1 1 1 CHD5-like protein NYD-SP28 PF14772.6 KXG52292.1 - 0.24 11.5 7.0 0.39 10.8 7.0 1.2 1 0 0 1 1 1 0 Sperm tail PPTA PF01239.22 KXG52293.1 - 8.5e-05 22.2 7.4 0.072 12.9 0.0 3.3 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat DUF3093 PF11292.8 KXG52294.1 - 0.066 13.5 0.2 0.066 13.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) Gram_pos_anchor PF00746.21 KXG52294.1 - 2.4 8.2 4.7 2 8.4 0.4 2.5 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DNA_pol_B_exo2 PF10108.9 KXG52295.1 - 0.15 11.7 0.2 0.24 11.1 0.2 1.2 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB zf-CHCC PF10276.9 KXG52295.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger domain TRAM_LAG1_CLN8 PF03798.16 KXG52296.1 - 1.5e-41 142.3 21.0 1.5e-41 142.3 21.0 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KXG52296.1 - 8.1e-19 67.0 0.0 1.8e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein Rad10 PF03834.14 KXG52298.1 - 1.6e-46 157.0 0.2 4.4e-46 155.6 0.2 1.8 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Zn_clus PF00172.18 KXG52298.1 - 1.1e-05 25.5 8.8 2e-05 24.6 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HHH_5 PF14520.6 KXG52298.1 - 0.00018 22.0 0.0 0.00043 20.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 KXG52298.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif Fungal_trans_2 PF11951.8 KXG52298.1 - 0.021 13.7 0.1 0.021 13.7 0.1 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain HHH_2 PF12826.7 KXG52298.1 - 0.083 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif RRM_1 PF00076.22 KXG52299.1 - 3.7e-60 199.7 0.1 2.3e-19 69.0 0.1 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KXG52299.1 - 3.9e-07 30.5 7.0 0.38 11.0 0.0 6.5 4 4 3 7 7 7 2 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 KXG52299.1 - 0.00031 20.6 0.1 0.52 10.1 0.0 3.2 2 1 1 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_5 PF13893.6 KXG52299.1 - 0.00094 18.8 0.0 0.28 10.8 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KXG52299.1 - 0.005 16.5 0.1 3.9 7.2 0.1 3.3 3 1 0 3 3 3 1 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 KXG52299.1 - 0.013 15.3 0.0 1.2 9.1 0.0 2.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif BSP_II PF05432.11 KXG52299.1 - 2.3 7.9 30.4 1.3 8.6 14.1 2.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Cyt-b5 PF00173.28 KXG52300.1 - 2.3e-09 37.3 0.0 2.5e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AA_permease PF00324.21 KXG52301.1 - 7.4e-105 351.3 31.4 9.5e-105 350.9 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG52301.1 - 2.4e-17 62.9 33.3 3.8e-17 62.2 33.3 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1289 PF06945.13 KXG52302.1 - 0.086 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Cupin_8 PF13621.6 KXG52303.1 - 5.3e-25 88.6 0.0 8.6e-25 87.9 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Amelin PF05111.12 KXG52303.1 - 0.096 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) Fungal_trans PF04082.18 KXG52304.1 - 1.6e-19 70.0 0.0 3.2e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.6 KXG52304.1 - 2.2e-10 40.3 0.0 0.00065 19.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXG52304.1 - 5e-08 31.8 0.0 9.2e-08 31.0 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXG52304.1 - 7.7e-07 28.6 0.0 1.1e-05 24.7 0.0 2.7 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Zn_clus PF00172.18 KXG52304.1 - 8.8e-07 29.0 6.2 1.6e-06 28.1 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_8 PF13450.6 KXG52304.1 - 3.3e-05 24.0 0.0 8.2e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXG52304.1 - 0.22 10.7 0.2 1.6 7.9 0.0 2.3 3 0 0 3 3 3 0 Thi4 family CK_II_beta PF01214.18 KXG52305.1 - 7.7e-78 260.5 0.0 1.8e-77 259.2 0.0 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit RRN3 PF05327.11 KXG52305.1 - 0.22 10.0 1.0 0.36 9.3 1.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Spt5_N PF11942.8 KXG52305.1 - 1.1 10.2 14.3 0.094 13.7 6.7 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DNA_pol_phi PF04931.13 KXG52305.1 - 1.9 6.5 4.2 3.4 5.7 4.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi bZIP_1 PF00170.21 KXG52306.1 - 0.00084 19.4 8.7 0.0016 18.5 8.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXG52306.1 - 0.017 15.2 8.2 0.017 15.2 8.2 1.6 2 0 0 2 2 2 0 Basic region leucine zipper Aminotran_4 PF01063.19 KXG52307.1 - 8e-36 124.0 0.0 1e-35 123.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase PF00069.25 KXG52308.1 - 2.7e-15 56.5 0.0 9.5e-15 54.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG52308.1 - 1.7e-08 34.1 0.0 1.5e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_M49 PF03571.15 KXG52309.1 - 4e-242 804.5 0.0 5.3e-242 804.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 SNF5 PF04855.12 KXG52310.1 - 4e-87 291.9 0.0 5.1e-87 291.6 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 KXG52310.1 - 7e-06 25.5 1.3 1.8e-05 24.2 1.3 1.7 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 KXG52310.1 - 0.11 12.3 4.6 0.13 12.0 1.2 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Methyltransf_25 PF13649.6 KXG52312.1 - 1.4e-19 70.6 0.0 2.8e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG52312.1 - 9.3e-19 67.9 0.0 1.7e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG52312.1 - 1.6e-16 60.6 0.0 2.2e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG52312.1 - 2.9e-12 47.2 0.0 6.2e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG52312.1 - 4.7e-10 39.5 0.0 6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG52312.1 - 4.9e-09 35.9 0.0 7.3e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 KXG52312.1 - 8.2e-07 28.8 0.0 1.1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 KXG52312.1 - 1.1e-05 24.9 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KXG52312.1 - 2.2e-05 24.0 0.0 3.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KXG52312.1 - 3.2e-05 23.3 0.0 3.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain CheR PF01739.18 KXG52312.1 - 0.00025 20.6 0.2 0.092 12.2 0.0 2.5 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain N2227 PF07942.12 KXG52312.1 - 0.0016 17.6 0.0 1 8.5 0.0 2.3 1 1 1 2 2 2 2 N2227-like protein UPF0146 PF03686.13 KXG52312.1 - 0.0064 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) Methyltransf_9 PF08003.11 KXG52312.1 - 0.0089 15.0 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_PK PF05891.12 KXG52312.1 - 0.009 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.7 KXG52312.1 - 0.013 15.5 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 KXG52312.1 - 0.017 14.8 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_10 PF05971.12 KXG52312.1 - 0.09 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 RNA methyltransferase XFP_N PF09364.10 KXG52313.1 - 2.1e-173 576.2 0.0 2.8e-173 575.9 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 KXG52313.1 - 1.4e-83 279.3 0.4 2.2e-83 278.7 0.0 1.5 2 0 0 2 2 2 1 XFP C-terminal domain XFP PF03894.15 KXG52313.1 - 4.2e-82 274.1 0.0 6.6e-82 273.5 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase UL42 PF17638.2 KXG52314.1 - 0.0063 16.5 2.5 0.011 15.7 2.5 1.3 1 0 0 1 1 1 1 HCMV UL42 ABM PF03992.16 KXG52315.1 - 0.005 16.9 0.1 0.0086 16.2 0.1 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase WD40 PF00400.32 KXG52318.1 - 3.3e-22 78.4 24.1 1.8e-05 25.4 0.2 7.1 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG52318.1 - 3.3e-10 40.1 9.0 0.00052 20.3 0.3 4.6 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KXG52318.1 - 0.00031 20.7 8.4 0.027 14.4 0.2 2.6 1 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term G-7-MTase PF12803.7 KXG52318.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Sugar_tr PF00083.24 KXG52319.1 - 4.9e-103 345.4 15.7 7.8e-103 344.7 15.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter ABC_tran PF00005.27 KXG52319.1 - 8.7e-48 162.3 0.3 4.6e-22 79.0 0.0 3.4 3 0 0 3 3 3 2 ABC transporter MFS_1 PF07690.16 KXG52319.1 - 1.6e-27 96.4 32.0 1.6e-27 96.4 32.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran_Xtn PF12848.7 KXG52319.1 - 5.6e-20 71.2 7.4 5.6e-20 71.2 7.4 2.7 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 KXG52319.1 - 3.6e-14 53.3 0.1 0.0072 16.2 0.0 4.5 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXG52319.1 - 5.6e-09 35.8 0.0 0.093 12.2 0.0 4.4 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXG52319.1 - 1.9e-06 28.2 0.0 0.0024 18.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 KXG52319.1 - 1.1e-05 25.9 0.8 0.13 12.6 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain TRI12 PF06609.13 KXG52319.1 - 1.8e-05 23.4 3.8 3.9e-05 22.3 3.8 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AAA_23 PF13476.6 KXG52319.1 - 1.8e-05 25.3 14.2 0.041 14.4 0.0 5.0 5 0 0 5 5 5 2 AAA domain AAA_30 PF13604.6 KXG52319.1 - 2.2e-05 24.3 0.1 0.0014 18.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KXG52319.1 - 4.4e-05 24.0 0.4 0.31 11.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 KXG52319.1 - 5.4e-05 23.3 0.0 0.31 11.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 KXG52319.1 - 5.8e-05 23.4 0.9 0.1 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXG52319.1 - 8.1e-05 22.3 0.2 0.44 10.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXG52319.1 - 9.4e-05 22.4 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 KXG52319.1 - 0.00038 20.2 0.8 1.2 8.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KXG52319.1 - 0.0014 18.8 0.1 1.3 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain LacY_symp PF01306.19 KXG52319.1 - 0.0019 17.0 5.6 0.0065 15.3 0.5 2.3 2 0 0 2 2 2 1 LacY proton/sugar symporter AAA_15 PF13175.6 KXG52319.1 - 0.0023 17.7 11.5 0.38 10.4 0.0 4.2 4 1 0 5 5 4 2 AAA ATPase domain MFS_3 PF05977.13 KXG52319.1 - 0.0028 16.1 7.8 0.0062 15.0 0.9 2.2 2 0 0 2 2 2 1 Transmembrane secretion effector AAA PF00004.29 KXG52319.1 - 0.0088 16.5 0.0 1.4 9.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXG52319.1 - 0.012 16.0 0.0 2.9 8.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase MeaB PF03308.16 KXG52319.1 - 0.012 14.6 0.1 5.4 5.9 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 KXG52319.1 - 0.016 15.2 0.2 2.1 8.2 0.0 2.6 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 KXG52319.1 - 0.019 14.6 0.0 0.59 9.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.23 KXG52319.1 - 0.019 15.0 2.6 2.7 8.0 0.0 3.6 4 0 0 4 4 4 0 Dynamin family Zeta_toxin PF06414.12 KXG52319.1 - 0.038 13.3 0.2 3.6 6.8 0.0 2.7 3 0 0 3 3 2 0 Zeta toxin AAA_27 PF13514.6 KXG52319.1 - 0.05 13.2 0.0 7.2 6.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KXG52319.1 - 0.055 13.5 0.0 11 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KXG52319.1 - 0.075 12.9 0.2 3.8 7.4 0.1 2.9 3 0 0 3 3 2 0 NTPase cobW PF02492.19 KXG52319.1 - 0.096 12.3 0.4 2.4 7.7 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KXG52319.1 - 0.1 12.1 0.0 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 KXG52319.1 - 0.12 12.4 0.1 13 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KXG52319.1 - 0.13 12.2 0.4 2.1 8.2 0.0 2.7 3 0 0 3 3 3 0 Rad17 P-loop domain Roc PF08477.13 KXG52319.1 - 0.17 12.1 0.8 29 4.9 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 KXG52319.1 - 0.18 11.4 0.5 2.4 7.7 0.1 2.6 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain MFS_1_like PF12832.7 KXG52319.1 - 1.4 7.7 17.4 0.47 9.3 7.4 3.3 1 1 1 2 2 1 0 MFS_1 like family DUF87 PF01935.17 KXG52319.1 - 2.5 8.1 6.5 5.2 7.1 0.0 3.6 4 0 0 4 4 2 0 Helicase HerA, central domain OCRE PF17780.1 KXG52321.1 - 0.0034 17.4 0.5 0.0073 16.3 0.5 1.6 1 0 0 1 1 1 1 OCRE domain SKG6 PF08693.10 KXG52322.1 - 6.8e-12 44.6 1.8 6.8e-12 44.6 1.8 2.9 3 0 0 3 3 3 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KXG52322.1 - 0.00052 19.8 0.1 0.00094 19.0 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) RIFIN PF02009.16 KXG52322.1 - 0.0014 18.6 0.1 0.0023 17.9 0.1 1.3 1 0 0 1 1 1 1 Rifin DUF2749 PF10907.8 KXG52322.1 - 0.47 10.7 0.0 0.47 10.7 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2749) TFIIA PF03153.13 KXG52322.1 - 1.6 8.7 6.8 2.4 8.0 6.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4551 PF15087.6 KXG52322.1 - 5.7 5.7 6.4 6.9 5.4 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ank_2 PF12796.7 KXG52323.1 - 2.1e-26 92.3 1.3 4e-10 40.1 0.0 4.7 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG52323.1 - 4.4e-20 71.8 8.1 1.6e-07 31.7 0.3 6.3 3 2 3 7 7 7 5 Ankyrin repeats (many copies) SPX PF03105.19 KXG52323.1 - 2e-19 70.8 12.9 5.6e-08 33.1 0.7 3.2 1 1 2 3 3 3 3 SPX domain GDPD PF03009.17 KXG52323.1 - 4.2e-16 59.5 0.0 5.1e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_3 PF13606.6 KXG52323.1 - 7.5e-16 56.6 6.1 0.0047 17.3 0.1 7.4 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 KXG52323.1 - 2.6e-15 56.3 2.0 0.016 15.5 0.3 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KXG52323.1 - 1.2e-07 31.9 6.9 0.014 15.8 0.3 5.6 5 1 0 5 5 5 2 Ankyrin repeat FAD-SLDH PF12318.8 KXG52323.1 - 0.19 11.8 0.3 23 5.0 0.0 2.5 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF1279 PF06916.13 KXG52324.1 - 3.7e-26 91.5 0.0 5.3e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Zeta_toxin PF06414.12 KXG52324.1 - 0.047 13.0 0.0 0.091 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Ribosomal_L3 PF00297.22 KXG52325.1 - 4.5e-18 65.4 6.0 4.5e-16 58.8 2.0 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 Coa1 PF08695.10 KXG52326.1 - 1.3e-43 147.5 0.0 1.6e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Glt_symporter PF03616.14 KXG52327.1 - 0.033 12.9 0.0 0.04 12.6 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF2973 PF11189.8 KXG52327.1 - 0.059 13.5 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) Deltameth_res PF16020.5 KXG52327.1 - 0.081 12.8 0.0 9.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Deltamethrin resistance JmjC PF02373.22 KXG52328.1 - 6.1e-08 33.1 0.2 7.1e-05 23.2 0.0 2.8 2 0 0 2 2 2 2 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 KXG52328.1 - 5.6e-06 26.5 13.3 5.6e-06 26.5 13.3 2.4 3 0 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 KXG52328.1 - 0.018 14.7 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Cupin domain MTES_1575 PF18741.1 KXG52328.1 - 0.11 12.7 0.3 2.9 8.1 0.0 2.6 2 0 0 2 2 2 0 REase_MTES_1575 UbiA PF01040.18 KXG52330.1 - 1.1e-44 152.7 15.2 1.4e-44 152.3 15.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Flavoprotein PF02441.19 KXG52331.1 - 9.9e-34 116.4 0.0 1.5e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein Glutaredoxin PF00462.24 KXG52332.1 - 2.5e-15 56.4 0.0 4.3e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin CTP_transf_like PF01467.26 KXG52333.1 - 2.4e-23 82.9 0.0 2.4e-20 73.2 0.0 2.8 2 1 0 3 3 3 2 Cytidylyltransferase-like PRELI PF04707.14 KXG52335.1 - 1.1e-42 145.6 0.3 1.2e-42 145.4 0.3 1.0 1 0 0 1 1 1 1 PRELI-like family BRCA-2_OB3 PF09104.10 KXG52335.1 - 0.046 13.4 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 AhpC-TSA PF00578.21 KXG52336.1 - 3.5e-22 78.6 0.0 5.8e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXG52336.1 - 7.7e-14 51.6 0.0 1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KXG52336.1 - 0.0077 16.3 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme adh_short PF00106.25 KXG52337.1 - 5.9e-20 71.6 0.2 6.9e-20 71.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG52337.1 - 3.7e-15 56.1 0.1 4.7e-15 55.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG52337.1 - 2.2e-08 34.2 0.1 3.1e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KXG52337.1 - 0.0048 16.3 0.1 0.0061 15.9 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KXG52337.1 - 0.036 13.2 0.2 0.044 12.9 0.2 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Urocanase PF01175.18 KXG52337.1 - 0.043 13.5 0.2 0.053 13.2 0.2 1.1 1 0 0 1 1 1 0 Urocanase Rossmann-like domain Mpp10 PF04006.12 KXG52338.1 - 1.4e-107 360.7 45.9 1e-106 357.9 45.9 2.0 1 1 0 1 1 1 1 Mpp10 protein Methyltransf_16 PF10294.9 KXG52339.1 - 1.4e-48 164.9 0.0 1.8e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KXG52339.1 - 0.002 18.0 0.0 0.0027 17.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXG52339.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DUF1761 PF08570.10 KXG52340.1 - 2e-27 95.9 3.7 2.3e-27 95.7 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) QCR10 PF09796.9 KXG52340.1 - 1 9.4 4.2 1.3 9.2 0.7 2.7 2 1 1 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Kinocilin PF15033.6 KXG52340.1 - 6 6.5 8.2 5.4 6.7 0.2 2.3 1 1 0 2 2 2 0 Kinocilin protein AA_permease PF00324.21 KXG52342.1 - 1.8e-113 379.7 40.5 2.2e-113 379.4 40.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG52342.1 - 9.7e-40 136.7 41.6 9.7e-40 136.7 41.6 1.3 1 1 0 1 1 1 1 Amino acid permease Oxidored_q6 PF01058.22 KXG52343.1 - 1.2e-22 80.1 0.0 2e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Sedlin_N PF04628.13 KXG52344.1 - 6.4e-13 49.0 0.0 8.1e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Acyl_transf_1 PF00698.21 KXG52345.1 - 1.3e-22 80.7 0.4 1.8e-15 57.2 0.2 2.1 2 0 0 2 2 2 2 Acyl transferase domain Cytochrom_B559 PF00283.19 KXG52345.1 - 0.96 8.9 3.6 4.2 6.9 0.0 2.6 3 0 0 3 3 3 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits Nucleoporin_C PF03177.14 KXG52346.1 - 4.6e-170 567.3 0.0 5.5e-170 567.0 0.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KXG52346.1 - 3.9e-78 263.1 0.0 5e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like HABP4_PAI-RBP1 PF04774.15 KXG52347.1 - 0.05 14.5 8.4 0.11 13.3 8.4 1.6 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family Ribosomal_S3Ae PF01015.18 KXG52348.1 - 7.3e-88 293.4 3.6 9.2e-88 293.1 3.6 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 KXG52348.1 - 0.047 14.2 0.3 0.13 12.8 0.0 1.9 2 0 0 2 2 2 0 Translation initiation factor SUI1 NEMO PF11577.8 KXG52348.1 - 0.1 12.6 0.4 0.86 9.7 0.0 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Abhydro_lipase PF04083.16 KXG52348.1 - 0.15 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Elf1 PF05129.13 KXG52349.1 - 9.2e-30 102.5 0.2 1.1e-29 102.2 0.2 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.15 KXG52349.1 - 0.031 14.3 0.6 0.92 9.6 0.2 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.10 KXG52349.1 - 0.075 13.2 0.2 0.17 12.0 0.2 1.6 1 1 0 1 1 1 0 Zinc ribbon domain EST1_DNA_bind PF10373.9 KXG52349.1 - 0.088 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain UPRTase PF14681.6 KXG52350.1 - 3.8e-78 261.7 0.0 4.3e-78 261.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KXG52350.1 - 0.007 15.9 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 KXG52350.1 - 0.22 11.5 0.2 0.34 10.9 0.2 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) WAPL PF07814.13 KXG52351.1 - 1.3e-74 251.2 0.3 1.9e-74 250.7 0.3 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Ras PF00071.22 KXG52352.1 - 1.5e-45 154.8 0.1 1.7e-45 154.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXG52352.1 - 1.4e-16 60.8 0.0 1.9e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG52352.1 - 3e-08 33.3 0.0 3.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXG52352.1 - 2.6e-05 24.3 0.0 3.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXG52352.1 - 4.9e-05 23.0 0.5 0.0011 18.6 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KXG52352.1 - 0.00047 19.6 0.0 0.00062 19.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KXG52352.1 - 0.0011 18.9 0.1 0.22 11.4 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 KXG52352.1 - 0.0059 16.9 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 KXG52352.1 - 0.013 15.0 0.0 0.13 11.8 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 KXG52352.1 - 0.025 14.6 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KXG52352.1 - 0.19 11.2 0.0 0.4 10.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein tRNA-synt_2b PF00587.25 KXG52353.1 - 4.5e-38 131.0 0.4 1.8e-37 129.0 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KXG52353.1 - 5.6e-19 68.4 5.8 5.6e-19 68.4 5.8 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Cytochrom_C552 PF02335.15 KXG52353.1 - 0.082 11.8 9.2 0.36 9.7 0.3 2.2 2 0 0 2 2 2 0 Cytochrome c552 2-Hacid_dh_C PF02826.19 KXG52354.1 - 7.4e-53 178.5 0.0 1.2e-52 177.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXG52354.1 - 7.3e-39 132.5 0.0 1e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXG52354.1 - 1.5e-05 25.3 1.9 2.5e-05 24.5 0.4 2.1 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KXG52354.1 - 3.7e-05 23.4 0.4 0.002 17.7 0.1 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 KXG52354.1 - 0.00076 19.6 0.8 0.0013 18.8 0.2 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 KXG52354.1 - 0.0039 16.9 0.2 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 ACT domain 3HCDH_N PF02737.18 KXG52354.1 - 0.077 12.9 2.0 1.1 9.2 0.9 2.9 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.25 KXG52355.1 - 1.2e-67 228.0 0.0 1.7e-67 227.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG52355.1 - 3.5e-31 108.4 0.0 5.2e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXG52355.1 - 0.0089 15.0 0.0 0.019 13.9 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KXG52355.1 - 0.054 13.1 0.1 8.7 5.9 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 P5-ATPase PF12409.8 KXG52356.1 - 9.9e-39 132.3 0.1 4.7e-38 130.1 0.0 2.2 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KXG52356.1 - 8.2e-32 110.2 0.0 1.7e-31 109.2 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KXG52356.1 - 1.6e-14 54.7 0.0 1.6e-05 25.3 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXG52356.1 - 0.001 19.1 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXG52356.1 - 0.0024 17.5 0.0 0.0058 16.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXG52356.1 - 0.085 12.6 0.0 11 5.7 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NAP PF00956.18 KXG52357.1 - 2.6e-98 328.5 9.9 2.6e-98 328.5 9.9 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TFIIA PF03153.13 KXG52357.1 - 0.041 13.9 16.1 0.096 12.7 16.1 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myosin_head PF00063.21 KXG52358.1 - 4e-266 884.6 1.4 5.7e-266 884.1 1.4 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KXG52358.1 - 4.1e-26 91.3 2.1 4.1e-26 91.3 2.1 2.8 2 1 1 3 3 3 1 DIL domain IQ PF00612.27 KXG52358.1 - 9e-14 49.9 33.5 3.2e-05 23.3 0.9 6.6 6 0 0 6 6 6 4 IQ calmodulin-binding motif Myosin_N PF02736.19 KXG52358.1 - 5.2e-06 26.2 0.4 1.3e-05 24.9 0.4 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain GAS PF13851.6 KXG52358.1 - 0.00074 18.9 29.1 0.015 14.6 15.0 2.7 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding AAA_22 PF13401.6 KXG52358.1 - 0.00094 19.5 0.2 0.006 16.9 0.1 2.4 2 1 0 2 2 1 1 AAA domain TMP_2 PF06791.13 KXG52358.1 - 0.0024 17.6 1.9 0.0048 16.6 1.9 1.4 1 0 0 1 1 1 1 Prophage tail length tape measure protein RsgA_GTPase PF03193.16 KXG52358.1 - 0.0029 17.5 0.0 0.0094 15.9 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KXG52358.1 - 0.0038 17.6 1.9 0.014 15.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Pox_A_type_inc PF04508.12 KXG52358.1 - 0.0054 16.5 0.3 0.0054 16.5 0.3 2.6 2 0 0 2 2 1 1 Viral A-type inclusion protein repeat RNA_helicase PF00910.22 KXG52358.1 - 0.16 12.3 0.0 0.64 10.4 0.0 2.1 1 0 0 1 1 1 0 RNA helicase FliJ PF02050.16 KXG52358.1 - 0.17 12.1 24.9 0.017 15.3 15.0 3.5 1 1 1 2 2 2 0 Flagellar FliJ protein Sec34 PF04136.15 KXG52358.1 - 0.18 11.7 7.0 0.62 9.9 7.0 2.0 1 0 0 1 1 1 0 Sec34-like family Herpes_BLRF2 PF05812.12 KXG52358.1 - 0.2 11.8 10.6 0.14 12.3 5.8 2.9 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Tropomyosin_1 PF12718.7 KXG52358.1 - 0.44 10.7 28.2 5.4 7.2 17.8 2.8 1 1 1 2 2 2 0 Tropomyosin like Baculo_PEP_C PF04513.12 KXG52358.1 - 0.94 9.5 11.4 0.13 12.3 5.1 2.8 3 0 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 KXG52358.1 - 1.3 7.4 7.5 3 6.2 7.5 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family ABC_tran PF00005.27 KXG52358.1 - 1.5 9.3 4.2 1.6 9.2 0.0 2.8 2 1 0 2 2 2 0 ABC transporter KASH_CCD PF14662.6 KXG52358.1 - 2.3 8.0 27.8 0.15 11.9 6.7 2.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF3450 PF11932.8 KXG52358.1 - 3.4 6.9 30.4 0.085 12.2 12.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Band_7 PF01145.25 KXG52358.1 - 8.3 6.4 7.6 23 4.9 7.6 1.8 1 0 0 1 1 1 0 SPFH domain / Band 7 family Ham1p_like PF01725.16 KXG52359.1 - 1.3e-60 204.6 0.0 1.4e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.6 KXG52360.1 - 2.6e-26 92.7 0.3 5.8e-26 91.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KXG52360.1 - 1.4e-08 35.3 0.0 3.1e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KXG52360.1 - 0.00015 22.2 0.0 0.00033 21.1 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXG52360.1 - 0.00083 19.8 0.0 0.0029 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain ADK PF00406.22 KXG52360.1 - 0.0029 17.7 0.1 0.014 15.5 0.1 2.1 1 1 0 1 1 1 1 Adenylate kinase RNA_helicase PF00910.22 KXG52360.1 - 0.0033 17.8 0.0 0.006 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 KXG52360.1 - 0.0037 17.5 0.0 0.0063 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KXG52360.1 - 0.0073 16.2 0.1 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 NTPase AAA_33 PF13671.6 KXG52360.1 - 0.0077 16.4 0.0 0.035 14.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 KXG52360.1 - 0.01 15.9 0.0 0.037 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXG52360.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KXG52360.1 - 0.021 14.3 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Death PF00531.22 KXG52360.1 - 0.035 14.3 0.8 2.5 8.3 0.0 2.6 3 0 0 3 3 3 0 Death domain Hydin_ADK PF17213.3 KXG52360.1 - 0.036 14.4 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF2075 PF09848.9 KXG52360.1 - 0.038 13.2 0.1 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 KXG52360.1 - 0.046 13.6 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 KXG52360.1 - 0.055 13.6 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 Cytidylate kinase-like family dNK PF01712.19 KXG52360.1 - 0.07 13.0 0.1 11 5.8 0.1 2.3 1 1 1 2 2 2 0 Deoxynucleoside kinase NACHT PF05729.12 KXG52360.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 KXG52360.1 - 0.17 11.9 0.1 0.43 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXG52360.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KXG52360.1 - 0.19 12.0 0.2 0.21 11.9 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXG52360.1 - 0.21 11.1 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KXG52360.1 - 0.35 10.6 1.4 2.1 8.0 0.3 2.3 2 1 1 3 3 3 0 AAA domain Peptidase_C78 PF07910.13 KXG52361.1 - 2e-71 239.8 0.0 2.7e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C39_2 PF13529.6 KXG52361.1 - 0.037 14.6 0.0 0.55 10.8 0.0 2.2 2 0 0 2 2 2 0 Peptidase_C39 like family Fungal_trans_2 PF11951.8 KXG52362.1 - 1.8e-07 30.4 0.3 3.9e-07 29.2 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3632 PF12311.8 KXG52363.1 - 2.5e-25 89.9 5.9 3.4e-25 89.5 5.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) AA_kinase PF00696.28 KXG52365.1 - 5.7e-40 137.4 0.1 9.4e-40 136.7 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 KXG52365.1 - 3.8e-11 42.6 1.3 9.2e-09 35.0 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KXG52365.1 - 7.4e-10 38.4 1.9 4.1e-07 29.7 0.1 3.4 3 0 0 3 3 3 2 ACT domain DUF515 PF04415.12 KXG52365.1 - 0.062 11.7 0.0 0.093 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Forkhead PF00250.18 KXG52366.1 - 1.3e-35 121.5 0.1 2.3e-35 120.7 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain G10 PF01125.17 KXG52367.1 - 8.9e-68 226.6 4.7 1e-67 226.5 4.7 1.0 1 0 0 1 1 1 1 G10 protein zf-Tim10_DDP PF02953.15 KXG52368.1 - 7.9e-22 76.7 2.8 1e-21 76.3 2.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF4756 PF15948.5 KXG52368.1 - 0.076 12.9 0.1 0.082 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) Ribosomal_L23eN PF03939.13 KXG52369.1 - 1.7e-23 82.5 7.5 3.3e-23 81.6 7.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KXG52369.1 - 2.7e-15 56.5 1.4 5.1e-15 55.6 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Bmt2 PF11968.8 KXG52370.1 - 5.2e-93 310.9 0.0 6.2e-93 310.7 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KXG52370.1 - 0.033 14.0 0.0 0.065 13.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Aa_trans PF01490.18 KXG52371.1 - 1.2e-69 235.0 26.0 1.5e-69 234.7 26.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MerC PF03203.14 KXG52371.1 - 0.0065 16.9 0.7 0.0065 16.9 0.7 3.2 2 1 0 2 2 2 1 MerC mercury resistance protein eRF1_2 PF03464.15 KXG52372.1 - 1.3e-45 155.0 0.0 2.2e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KXG52372.1 - 6e-37 126.6 0.6 1.3e-36 125.5 0.6 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KXG52372.1 - 3.5e-22 78.8 0.0 7.8e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KXG52372.1 - 1.2e-07 32.0 0.0 2.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KXG52372.1 - 2.1e-07 31.3 0.0 3.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Ribosomal_L7Ae PF01248.26 KXG52372.1 - 0.094 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PDT PF00800.18 KXG52373.1 - 1.1e-62 211.1 0.0 1.6e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KXG52373.1 - 0.001 18.8 0.0 0.0026 17.5 0.0 1.7 1 0 0 1 1 1 1 ACT domain MaoC_dehydratas PF01575.19 KXG52374.1 - 0.027 14.0 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 MaoC like domain DKCLD PF08068.12 KXG52375.1 - 3.6e-32 110.2 0.6 7.5e-31 106.0 0.3 2.8 3 0 0 3 3 3 1 DKCLD (NUC011) domain DER1 PF04511.15 KXG52375.1 - 4.2e-26 92.1 6.8 5.8e-26 91.6 6.8 1.2 1 0 0 1 1 1 1 Der1-like family TruB_C_2 PF16198.5 KXG52375.1 - 3.1e-22 78.5 0.2 6e-22 77.6 0.2 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 KXG52375.1 - 2.4e-21 76.7 1.2 6.4e-19 68.8 0.2 3.6 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 KXG52375.1 - 4.8e-21 74.5 1.3 8.9e-21 73.6 1.3 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KXG52375.1 - 0.003 17.8 0.0 0.0068 16.6 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain Med19 PF10278.9 KXG52375.1 - 8.4 6.3 19.0 17 5.3 19.0 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CLTH PF10607.9 KXG52376.1 - 6.2e-36 123.5 1.4 1.2e-35 122.6 1.4 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain YhdB PF14148.6 KXG52376.1 - 0.0079 16.3 0.5 0.049 13.7 0.1 2.3 2 0 0 2 2 2 1 YhdB-like protein LisH PF08513.11 KXG52376.1 - 0.061 13.3 0.0 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 LisH U-box PF04564.15 KXG52376.1 - 0.073 13.3 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 U-box domain DUF3673 PF12425.8 KXG52376.1 - 0.13 12.2 0.1 1.3 9.0 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3673) UL73_N PF12522.8 KXG52376.1 - 0.44 10.3 8.5 0.88 9.4 8.5 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal GIT_CC PF16559.5 KXG52376.1 - 5.3 7.0 6.6 4.7 7.2 0.9 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2431 PF10354.9 KXG52377.1 - 4.1e-62 209.4 0.0 7.7e-62 208.5 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) RR_TM4-6 PF06459.12 KXG52377.1 - 3.3 7.4 6.8 1.4 8.7 2.7 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Sigma70_ner PF04546.13 KXG52377.1 - 8.9 6.1 12.4 11 5.8 3.7 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.14 KXG52377.1 - 9.8 4.3 11.2 2.5 6.3 3.3 2.2 2 0 0 2 2 2 0 CDC45-like protein Presenilin PF01080.17 KXG52377.1 - 9.9 4.8 4.8 1.7 7.3 1.5 1.5 2 0 0 2 2 2 0 Presenilin EamA PF00892.20 KXG52378.1 - 3e-05 24.2 6.3 3e-05 24.2 6.3 2.2 2 0 0 2 2 2 1 EamA-like transporter family DUF1077 PF06417.12 KXG52378.1 - 0.35 10.9 4.7 3.2 7.8 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) Thioredoxin PF00085.20 KXG52379.1 - 0.00044 20.2 0.0 0.00073 19.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin SMI1_KNR4 PF09346.10 KXG52380.1 - 7.7e-33 113.7 0.0 1.6e-32 112.6 0.0 1.6 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) RTA1 PF04479.13 KXG52381.1 - 1.4e-75 253.5 7.5 2.3e-75 252.8 7.5 1.3 1 0 0 1 1 1 1 RTA1 like protein GBP_repeat PF02526.14 KXG52381.1 - 0.19 11.5 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Glycophorin-binding protein Fungal_trans_2 PF11951.8 KXG52382.1 - 9e-07 28.0 0.1 4.1e-06 25.9 0.0 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.13 KXG52383.1 - 1.7e-69 233.6 22.5 1.8e-69 233.5 13.3 2.0 2 0 0 2 2 2 2 RTA1 like protein PNRC PF15365.6 KXG52384.1 - 9.1e-09 34.9 7.7 9.1e-09 34.9 7.7 5.3 7 0 0 7 7 7 2 Proline-rich nuclear receptor coactivator motif zf-rbx1 PF12678.7 KXG52385.1 - 3.7e-25 88.0 12.8 5.3e-25 87.5 12.8 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXG52385.1 - 1.9e-17 63.1 10.3 2.5e-17 62.7 10.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KXG52385.1 - 2.8e-06 27.6 14.8 9.9e-05 22.6 14.8 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXG52385.1 - 9.9e-05 22.1 3.7 9.9e-05 22.1 3.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXG52385.1 - 0.0014 18.4 11.9 0.026 14.4 11.9 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KXG52385.1 - 0.2 11.9 9.2 0.87 9.8 9.3 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 KXG52385.1 - 0.26 11.2 10.6 0.63 9.9 4.4 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXG52385.1 - 0.43 10.7 7.8 1.6 8.8 7.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KXG52385.1 - 0.6 9.8 14.7 0.11 12.1 4.6 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KXG52385.1 - 1 9.2 17.1 95 2.9 17.1 2.5 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 KXG52385.1 - 8.5 6.4 11.4 48 4.0 11.4 2.3 1 1 0 1 1 1 0 zinc-RING finger domain SPC12 PF06645.13 KXG52386.1 - 1.2e-27 95.8 0.2 1.4e-27 95.6 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ZYG-11_interact PF05884.12 KXG52386.1 - 0.052 12.9 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF3040 PF11239.8 KXG52386.1 - 0.11 12.8 0.3 0.14 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Neurensin PF14927.6 KXG52386.1 - 0.51 10.1 2.5 1.9 8.2 1.8 1.8 1 1 1 2 2 2 0 Neurensin GHMP_kinases_N PF00288.26 KXG52387.1 - 1.9e-07 31.2 1.3 1.3e-05 25.3 1.3 2.5 1 1 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXG52387.1 - 5.6e-06 26.6 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal CorA PF01544.18 KXG52388.1 - 1.4e-43 149.3 0.0 2e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Mid1 PF12929.7 KXG52389.1 - 4.9e-156 520.2 1.3 5.9e-156 519.9 1.3 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KXG52389.1 - 0.0087 16.7 6.7 0.14 12.8 2.3 2.7 2 1 0 2 2 2 2 Fz domain Oxidored-like PF09791.9 KXG52390.1 - 8.9e-06 25.3 4.8 1.7e-05 24.4 4.8 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal PAP1 PF08601.10 KXG52390.1 - 2.6 7.7 10.5 3.1 7.4 10.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Es2 PF09751.9 KXG52391.1 - 7.9e-135 450.9 10.3 9.4e-135 450.7 10.3 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 APOC4 PF15119.6 KXG52391.1 - 0.012 15.9 0.1 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 Apolipoprotein C4 Mcm10 PF09332.11 KXG52392.1 - 0.042 13.3 0.6 0.063 12.7 0.6 1.1 1 0 0 1 1 1 0 Mcm10 replication factor TPR_2 PF07719.17 KXG52394.1 - 3.1e-26 89.3 23.9 0.00031 20.6 0.4 11.2 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 KXG52394.1 - 3e-21 74.3 16.5 0.0021 17.8 0.0 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXG52394.1 - 3.6e-18 65.8 25.3 3.6e-06 27.4 0.1 8.7 9 1 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXG52394.1 - 5.7e-11 42.3 32.4 0.046 14.6 0.2 11.2 11 1 1 12 12 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXG52394.1 - 1.2e-10 40.7 16.1 0.22 11.8 0.0 9.9 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXG52394.1 - 1.8e-07 30.7 11.3 0.8 9.4 0.0 7.5 7 1 1 8 8 8 2 TPR repeat TPR_7 PF13176.6 KXG52394.1 - 2.9e-06 26.9 23.0 0.0037 17.2 0.1 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXG52394.1 - 1.2e-05 25.9 30.1 0.041 14.5 0.6 8.5 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXG52394.1 - 2.3e-05 24.7 29.8 0.034 14.8 0.1 11.7 14 0 0 14 14 12 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXG52394.1 - 2.6e-05 24.4 29.2 0.021 15.1 0.4 8.0 8 2 1 9 9 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXG52394.1 - 4.1e-05 23.7 12.5 0.83 10.2 0.0 9.3 10 0 0 10 10 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG52394.1 - 0.012 15.9 8.7 18 5.7 0.1 6.2 6 1 0 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 GGDEF_2 PF17853.1 KXG52394.1 - 0.017 15.4 0.0 0.15 12.4 0.0 2.7 2 0 0 2 2 2 0 GGDEF-like domain TPR_4 PF07721.14 KXG52394.1 - 0.025 15.2 3.9 4.4 8.2 1.2 4.9 4 0 0 4 4 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXG52394.1 - 0.32 11.1 3.7 12 6.0 0.1 4.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KXG52394.1 - 6.9 6.7 34.1 3.1 7.8 0.2 8.8 9 0 0 9 9 8 0 Tetratricopeptide repeat Acyltransferase PF01553.21 KXG52395.1 - 2.7e-27 95.0 0.0 3.9e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KXG52395.1 - 5e-14 52.1 0.0 9.7e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus NAD_kinase PF01513.21 KXG52396.1 - 9.1e-49 166.2 0.0 1.4e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KXG52396.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Pkinase PF00069.25 KXG52397.1 - 2e-66 224.0 1.4 1.1e-65 221.6 0.2 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG52397.1 - 8.6e-50 169.4 0.0 1.7e-49 168.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KXG52397.1 - 1.2e-24 86.4 0.3 6.4e-24 84.1 0.0 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.6 KXG52397.1 - 4e-11 43.3 0.0 9.9e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 KXG52397.1 - 7.9e-06 25.4 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXG52397.1 - 9.2e-05 21.4 0.0 9.2e-05 21.4 0.0 1.9 3 0 0 3 3 3 1 Fungal protein kinase PH PF00169.29 KXG52397.1 - 0.0002 21.8 0.0 0.00052 20.5 0.0 1.7 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 KXG52397.1 - 0.00022 20.3 0.0 0.0004 19.4 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXG52397.1 - 0.012 15.6 0.3 0.047 13.6 0.4 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KXG52397.1 - 0.056 12.5 0.1 0.094 11.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HGTP_anticodon PF03129.20 KXG52399.1 - 4.7e-22 77.9 0.5 2.8e-21 75.5 0.0 2.7 2 1 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KXG52399.1 - 1.1e-07 31.9 0.0 5.3e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Brix PF04427.18 KXG52400.1 - 1.3e-24 87.4 0.0 2.5e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.10 KXG52400.1 - 0.053 12.9 18.7 0.073 12.4 18.7 1.1 1 0 0 1 1 1 0 BUD22 Hid1 PF12722.7 KXG52400.1 - 3 5.9 5.3 3.5 5.6 5.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.12 KXG52400.1 - 5.2 5.2 21.0 7.3 4.7 21.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4820 PF16091.5 KXG52400.1 - 5.9 6.2 11.0 9.5 5.5 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Pept_tRNA_hydro PF01195.19 KXG52401.1 - 3.6e-20 72.6 0.0 1.8e-11 44.3 0.0 3.1 1 1 1 2 2 2 2 Peptidyl-tRNA hydrolase BAR PF03114.18 KXG52402.1 - 4.1e-64 216.5 5.3 5e-64 216.2 5.3 1.1 1 0 0 1 1 1 1 BAR domain DUF3340 PF11818.8 KXG52402.1 - 0.0058 16.8 0.8 0.0058 16.8 0.8 1.8 2 0 0 2 2 2 1 C-terminal domain of tail specific protease (DUF3340) CP12 PF02672.15 KXG52402.1 - 0.012 16.4 0.1 0.07 13.9 0.0 2.4 2 2 0 2 2 2 0 CP12 domain DUF2884 PF11101.8 KXG52402.1 - 0.32 10.5 3.4 2.9 7.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Pkinase PF00069.25 KXG52403.1 - 9.4e-48 162.9 0.0 1.6e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG52403.1 - 8.3e-27 94.1 0.0 1.1e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXG52403.1 - 0.0056 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXG52403.1 - 0.0099 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXG52403.1 - 0.02 14.8 1.0 1.6 8.6 0.0 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Sybindin PF04099.12 KXG52404.1 - 1.3e-23 83.5 0.0 1.6e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KXG52404.1 - 0.064 13.4 0.1 0.089 12.9 0.1 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Pkinase PF00069.25 KXG52405.1 - 3.5e-53 180.7 0.0 2.7e-47 161.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG52405.1 - 9.6e-34 116.8 0.0 5.9e-32 111.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXG52405.1 - 1.2e-08 34.6 0.0 3.4e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXG52405.1 - 0.0026 17.7 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXG52405.1 - 0.0067 15.2 0.0 0.023 13.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase AT_hook PF02178.19 KXG52406.1 - 0.0026 17.4 1.3 0.016 15.0 1.3 2.5 1 0 0 1 1 1 1 AT hook motif DUF4684 PF15736.5 KXG52406.1 - 1.5 7.5 4.9 2 7.0 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) SRI PF08236.11 KXG52407.1 - 9.3e-19 67.4 7.7 2.5e-18 66.0 7.7 1.8 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KXG52407.1 - 1.1e-16 61.7 2.0 2.3e-16 60.6 0.2 2.6 2 1 0 2 2 2 1 SET domain AWS PF17907.1 KXG52407.1 - 1.9e-11 43.8 9.2 1.9e-11 43.8 9.2 2.2 2 0 0 2 2 2 1 AWS domain WW PF00397.26 KXG52407.1 - 0.00023 21.2 1.8 0.00062 19.8 1.8 1.8 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 KXG52407.1 - 0.00059 19.8 0.2 0.002 18.1 0.0 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain PRIMA1 PF16101.5 KXG52407.1 - 2.9 8.0 6.7 12 6.0 6.7 2.0 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 eIF-6 PF01912.18 KXG52408.1 - 6.2e-80 267.2 0.8 9e-80 266.7 0.8 1.2 1 0 0 1 1 1 1 eIF-6 family DUF3889 PF13028.6 KXG52409.1 - 0.049 13.6 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) CPP1-like PF11833.8 KXG52410.1 - 0.34 10.6 4.2 0.67 9.6 3.8 1.6 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like XPC-binding PF09280.11 KXG52411.1 - 7.6e-23 80.0 11.8 1.4e-22 79.2 11.8 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 KXG52411.1 - 1.8e-22 78.8 2.0 3.5e-13 49.2 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 KXG52411.1 - 3.1e-19 68.5 1.3 3.1e-19 68.5 1.3 1.9 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 KXG52411.1 - 3.5e-05 23.6 3.0 7.3e-05 22.5 3.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KXG52411.1 - 0.00046 20.3 0.0 0.0009 19.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KXG52411.1 - 0.0012 19.2 0.5 0.002 18.4 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 KXG52411.1 - 0.0017 18.9 0.0 0.0038 17.8 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF4515 PF14988.6 KXG52411.1 - 0.007 16.2 0.8 0.017 15.0 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) UBA_3 PF09288.10 KXG52411.1 - 0.029 14.2 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Herpes_LMP1 PF05297.11 KXG52411.1 - 0.22 10.7 0.4 0.35 10.0 0.4 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Glyco_transf_22 PF03901.17 KXG52412.1 - 3.1e-47 161.7 21.9 3.8e-47 161.5 21.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ThrE PF06738.12 KXG52412.1 - 0.061 12.7 0.4 0.19 11.1 0.4 1.8 1 0 0 1 1 1 0 Putative threonine/serine exporter Skp1 PF01466.19 KXG52413.1 - 2.6e-28 97.9 0.5 4.5e-28 97.1 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KXG52413.1 - 5.9e-24 84.0 0.2 1.5e-23 82.7 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Ribosomal_L39 PF00832.20 KXG52414.1 - 8.3e-20 70.2 12.5 1.6e-19 69.3 12.5 1.5 1 0 0 1 1 1 1 Ribosomal L39 protein APH PF01636.23 KXG52414.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC_membrane PF00664.23 KXG52415.1 - 1e-96 323.8 32.8 3.2e-50 171.3 12.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXG52415.1 - 5.7e-68 227.7 0.0 6.7e-33 114.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXG52415.1 - 2e-14 53.6 0.0 1.6e-05 24.5 0.6 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 KXG52415.1 - 1.9e-07 31.6 0.2 3.3 8.1 0.0 4.6 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXG52415.1 - 2.5e-07 31.2 3.2 0.015 15.7 0.1 3.6 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KXG52415.1 - 6e-07 29.1 0.8 0.0046 16.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KXG52415.1 - 1.7e-06 27.2 0.6 0.024 13.4 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 KXG52415.1 - 3.4e-06 27.4 2.0 0.036 14.4 0.0 3.7 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXG52415.1 - 3.3e-05 23.9 0.0 0.46 10.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KXG52415.1 - 3.6e-05 23.6 1.5 0.5 10.1 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_21 PF13304.6 KXG52415.1 - 4.8e-05 23.3 0.1 0.17 11.7 0.0 3.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KXG52415.1 - 0.0002 21.4 0.1 0.03 14.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 KXG52415.1 - 0.00046 19.8 0.0 0.38 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXG52415.1 - 0.0016 18.5 0.7 3.6 7.6 0.0 3.2 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXG52415.1 - 0.0016 18.9 0.0 2 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KXG52415.1 - 0.002 17.9 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KXG52415.1 - 0.0021 17.6 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 KXG52415.1 - 0.0022 18.2 0.0 2.8 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain Tho1_MOS11_C PF18592.1 KXG52415.1 - 0.0053 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Tho1/MOS11 C-terminal domain AAA_23 PF13476.6 KXG52415.1 - 0.0056 17.2 0.2 6.1 7.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KXG52415.1 - 0.012 16.0 0.1 3.8 8.0 0.0 3.4 3 0 0 3 3 3 0 RNA helicase SRP54 PF00448.22 KXG52415.1 - 0.016 14.8 0.1 1.7 8.2 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KXG52415.1 - 0.019 14.7 0.1 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXG52415.1 - 0.029 14.6 0.2 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXG52415.1 - 0.033 13.5 0.0 11 5.3 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.6 KXG52415.1 - 0.036 14.3 8.4 1.9 8.8 0.3 4.4 4 2 0 4 4 3 0 Putative exonuclease SbcCD, C subunit Cytidylate_kin PF02224.18 KXG52415.1 - 0.037 13.8 0.0 3.6 7.3 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase PRK PF00485.18 KXG52415.1 - 0.047 13.4 0.1 2.8 7.6 0.0 2.7 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family DUF2207 PF09972.9 KXG52415.1 - 0.095 11.5 0.0 0.095 11.5 0.0 3.4 4 1 0 4 4 4 0 Predicted membrane protein (DUF2207) DUF87 PF01935.17 KXG52415.1 - 0.098 12.7 0.3 14 5.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Cu_bind_CorA PF18252.1 KXG52415.1 - 0.13 11.8 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Copper(I)-binding protein CorA G-alpha PF00503.20 KXG52415.1 - 0.15 11.2 0.0 9.2 5.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_17 PF13207.6 KXG52415.1 - 0.32 11.4 2.2 23 5.4 0.2 3.3 4 0 0 4 4 2 0 AAA domain CitMHS PF03600.16 KXG52415.1 - 4.2 6.5 21.6 0.02 14.1 10.3 2.5 2 1 0 2 2 2 0 Citrate transporter Swi5 PF07061.11 KXG52416.1 - 4.1e-26 90.9 0.3 5e-26 90.6 0.3 1.1 1 0 0 1 1 1 1 Swi5 ABC_tran_CTD PF16326.5 KXG52416.1 - 6.3e-05 23.1 0.1 9.5e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 ABC transporter C-terminal domain DUF4407 PF14362.6 KXG52416.1 - 0.014 14.7 0.2 0.014 14.7 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 KXG52416.1 - 0.27 9.7 0.5 0.26 9.8 0.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ytp1 PF10355.9 KXG52417.1 - 1.4e-71 241.0 20.2 5.6e-71 239.0 20.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KXG52417.1 - 1e-32 112.0 0.7 1e-32 112.0 0.7 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) ApoO PF09769.9 KXG52417.1 - 0.071 13.1 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 Apolipoprotein O S1FA PF04689.13 KXG52417.1 - 0.82 9.9 2.7 1.3 9.3 0.2 2.4 2 0 0 2 2 2 0 DNA binding protein S1FA ThiF PF00899.21 KXG52418.1 - 5.5e-28 98.0 0.0 7e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family Asp_protease PF09668.10 KXG52420.1 - 8.7e-61 203.2 0.1 1.3e-60 202.6 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KXG52420.1 - 7.8e-22 77.7 0.0 1.8e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KXG52420.1 - 1.5e-10 41.6 0.1 4e-10 40.2 0.0 1.8 2 0 0 2 2 1 1 Aspartyl protease ubiquitin PF00240.23 KXG52420.1 - 2.4e-09 36.8 0.1 4.1e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXG52420.1 - 3.6e-05 23.5 0.1 8.7e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 KXG52420.1 - 0.00018 21.3 0.1 0.00052 19.9 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain RVP_2 PF08284.11 KXG52420.1 - 0.0011 18.7 0.0 0.0026 17.6 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KXG52420.1 - 0.012 15.9 0.0 0.04 14.2 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease UBA_4 PF14555.6 KXG52420.1 - 0.026 14.3 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain NAD_binding_7 PF13241.6 KXG52420.1 - 0.054 13.9 0.0 0.67 10.4 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding TBK1_ULD PF18396.1 KXG52420.1 - 0.08 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain RuvA_C PF07499.13 KXG52420.1 - 0.14 12.7 0.2 2.3 8.8 0.0 2.7 2 0 0 2 2 2 0 RuvA, C-terminal domain Ubiquitin_4 PF18036.1 KXG52420.1 - 0.15 12.1 0.1 7.1 6.8 0.0 3.0 2 1 1 3 3 3 0 Ubiquitin-like domain DUF2781 PF10914.8 KXG52421.1 - 2.9e-41 141.3 12.1 3.3e-41 141.1 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) TauD PF02668.16 KXG52422.1 - 8.9e-46 156.8 0.1 1.1e-45 156.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UPF0302 PF08864.10 KXG52422.1 - 0.013 15.6 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 UPF0302 domain Nucleoporin_N PF08801.11 KXG52423.1 - 4.9e-79 266.1 2.4 1.1e-78 265.0 2.4 1.6 1 1 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KXG52423.1 - 1.1e-47 163.1 1.3 7.4e-45 153.8 0.3 2.1 2 0 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal Imm35 PF15567.6 KXG52423.1 - 0.12 12.5 0.0 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 35 YqeY PF09424.10 KXG52424.1 - 5.1e-20 72.0 4.1 5.8e-20 71.8 4.1 1.0 1 0 0 1 1 1 1 Yqey-like protein ParcG PF10274.9 KXG52424.1 - 0.12 12.5 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Parkin co-regulated protein Rot1 PF10681.9 KXG52425.1 - 1.6e-89 299.0 0.0 1.8e-89 298.8 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal 5-FTHF_cyc-lig PF01812.20 KXG52426.1 - 4.5e-36 124.5 0.0 5.5e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family ATP-grasp_6 PF18419.1 KXG52426.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp-like domain LSM PF01423.22 KXG52427.1 - 5.2e-14 51.7 0.0 6e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KXG52427.1 - 0.0019 17.8 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Hfq protein Xpo1 PF08389.12 KXG52428.1 - 3.3e-27 95.4 0.1 7.3e-26 91.0 0.0 3.0 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 KXG52428.1 - 1.8e-05 24.5 0.0 7.7e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Fungal_trans PF04082.18 KXG52429.1 - 1e-67 228.0 0.1 1.4e-67 227.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXG52429.1 - 0.00039 20.7 15.5 0.0014 19.0 0.8 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXG52429.1 - 0.013 16.3 9.5 0.071 14.0 0.6 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXG52429.1 - 0.45 11.0 5.5 0.85 10.2 1.2 2.8 2 0 0 2 2 2 0 Zinc-finger double domain EF-hand_7 PF13499.6 KXG52430.1 - 8.8e-12 45.3 0.5 4.5e-08 33.4 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KXG52430.1 - 9.7e-10 38.6 0.0 0.00053 20.3 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 KXG52430.1 - 2.6e-08 33.1 1.9 0.013 15.4 0.1 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KXG52430.1 - 3.2e-07 29.4 1.2 0.024 14.2 0.0 3.8 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KXG52430.1 - 2.1e-06 27.5 0.2 0.00011 22.0 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair DUF3216 PF11505.8 KXG52430.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Peptidase_M3 PF01432.20 KXG52432.1 - 1.7e-162 541.9 0.0 2.3e-162 541.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 SUV3_C PF12513.8 KXG52432.1 - 0.035 14.0 0.1 0.099 12.6 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal FA_desaturase PF00487.24 KXG52433.1 - 1.4e-19 70.9 13.6 1.4e-19 70.9 13.6 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXG52433.1 - 1.6e-16 60.2 0.2 4.7e-16 58.7 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF2225 PF09986.9 KXG52433.1 - 0.014 15.1 0.0 0.035 13.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF1189 PF06691.11 KXG52433.1 - 0.18 11.4 0.2 0.35 10.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) MFS_1 PF07690.16 KXG52434.1 - 3.7e-21 75.4 57.9 5.4e-12 45.3 28.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KXG52435.1 - 9.4e-09 34.7 3.1 1.5e-08 34.0 3.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Xan_ur_permease PF00860.20 KXG52437.1 - 9.5e-64 215.5 28.9 2.7e-63 214.0 28.9 1.6 1 1 0 1 1 1 1 Permease family MOSC PF03473.17 KXG52439.1 - 6.3e-25 87.7 0.0 8.9e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXG52439.1 - 1e-07 31.9 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Rad51 PF08423.11 KXG52440.1 - 1.1e-13 51.1 0.0 2.4e-13 49.9 0.0 1.6 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 KXG52440.1 - 1.9e-07 30.8 0.0 5.4e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KXG52440.1 - 1.4e-05 24.6 0.0 4.3e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 KXG52440.1 - 0.00011 21.9 0.0 0.00065 19.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXG52440.1 - 0.0028 17.4 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 KXG52440.1 - 0.0068 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 KXG52440.1 - 0.038 14.4 0.0 0.083 13.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KXG52440.1 - 0.042 13.2 0.0 0.093 12.0 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KXG52440.1 - 0.046 13.5 0.0 0.11 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXG52440.1 - 0.056 14.0 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 KXG52440.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXG52440.1 - 0.088 13.2 0.1 0.2 12.0 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 KXG52440.1 - 0.16 12.0 0.2 0.61 10.1 0.2 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zot PF05707.12 KXG52440.1 - 0.18 11.4 0.0 0.74 9.4 0.0 1.8 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) Proteasome PF00227.26 KXG52442.1 - 6.9e-57 192.0 0.0 7.2e-32 110.4 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KXG52442.1 - 8.8e-11 41.3 0.1 3.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.15 KXG52442.1 - 0.056 12.2 0.1 0.78 8.4 0.0 2.0 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family RINGv PF12906.7 KXG52443.1 - 5.4e-09 36.0 5.0 9.2e-09 35.3 1.4 2.3 2 0 0 2 2 2 1 RING-variant domain zf-BED PF02892.15 KXG52443.1 - 0.081 13.0 0.3 0.081 13.0 0.3 2.0 2 0 0 2 2 2 0 BED zinc finger DUF2752 PF10825.8 KXG52443.1 - 0.29 11.2 2.3 0.47 10.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) zf-RING_2 PF13639.6 KXG52443.1 - 0.36 11.2 4.7 1.2 9.5 1.7 2.2 2 0 0 2 2 2 0 Ring finger domain PHD PF00628.29 KXG52443.1 - 0.61 10.0 5.3 0.22 11.5 2.3 1.7 2 0 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 KXG52443.1 - 1.2 9.2 5.4 6.1 7.0 5.4 2.0 1 1 0 1 1 1 0 PHD-finger TRF PF08558.10 KXG52444.1 - 0.0051 16.4 0.1 0.0071 16.0 0.1 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Amidohydro_2 PF04909.14 KXG52445.1 - 7.8e-38 130.9 3.6 9.8e-38 130.6 2.1 1.7 1 1 1 2 2 2 1 Amidohydrolase Acid_PPase PF12689.7 KXG52445.1 - 0.014 15.3 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Acid Phosphatase p450 PF00067.22 KXG52447.1 - 3e-24 85.6 0.0 4.8e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 KXG52448.1 - 5.9e-79 266.0 19.8 5.9e-79 266.0 19.8 1.4 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG52448.1 - 2.1e-10 40.1 41.2 4.7e-08 32.3 8.5 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily RRM_1 PF00076.22 KXG52449.1 - 5.3e-17 61.4 0.0 8.8e-13 47.9 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KXG52449.1 - 0.09 12.9 0.0 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 6PF2K PF01591.18 KXG52450.1 - 4e-78 261.7 0.0 5.5e-78 261.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXG52450.1 - 1.2e-39 136.0 0.1 2.1e-39 135.2 0.1 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KXG52450.1 - 7.2e-05 23.0 0.0 0.00021 21.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KXG52450.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Vps39_1 PF10366.9 KXG52451.1 - 6.9e-31 106.7 0.0 4.4e-28 97.7 0.0 3.2 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KXG52451.1 - 6.6e-29 100.6 0.0 2.9e-28 98.5 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KXG52451.1 - 4.8e-18 65.7 0.0 1e-17 64.6 0.0 1.5 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 KXG52451.1 - 3.4e-10 39.9 6.6 1.2e-08 34.9 4.7 2.8 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_1 PF00515.28 KXG52451.1 - 0.0016 18.2 1.2 17 5.4 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 KXG52451.1 - 0.11 12.8 0.3 17 5.9 0.0 4.3 5 0 0 5 5 5 0 PPR repeat TPR_7 PF13176.6 KXG52451.1 - 0.13 12.4 2.6 52 4.2 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG52451.1 - 0.21 11.8 2.0 10 6.4 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KXG52451.1 - 0.25 12.1 1.7 3.1e+02 2.3 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXG52451.1 - 0.3 11.3 1.6 25 5.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXG52451.1 - 3.8 7.9 8.4 52 4.2 0.1 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Gon7 PF08738.10 KXG52452.1 - 5.1e-12 45.8 5.2 6.8e-12 45.4 1.7 1.9 1 1 1 2 2 2 1 Gon7 family Interferon PF00143.19 KXG52452.1 - 0.091 12.9 1.0 0.11 12.7 1.0 1.1 1 0 0 1 1 1 0 Interferon alpha/beta domain HbrB PF08539.11 KXG52453.1 - 7.3e-47 159.5 0.0 1.6e-46 158.4 0.0 1.6 1 0 0 1 1 1 1 HbrB-like DUF3263 PF11662.8 KXG52454.1 - 0.069 13.0 0.4 0.15 11.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) AAA PF00004.29 KXG52455.1 - 3.6e-16 59.8 0.0 1.4e-15 57.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXG52455.1 - 0.00059 20.1 0.6 0.0075 16.5 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KXG52455.1 - 0.00085 19.3 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXG52455.1 - 0.0014 19.0 0.1 0.0078 16.6 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KXG52455.1 - 0.004 16.9 1.0 0.021 14.6 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXG52455.1 - 0.0064 16.8 0.3 0.023 15.0 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KXG52455.1 - 0.023 14.5 0.0 0.023 14.5 0.0 3.6 2 1 1 3 3 3 0 AAA domain HhH-GPD PF00730.25 KXG52455.1 - 0.057 13.9 0.1 1.1 9.7 0.0 2.6 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein Peptidase_S64 PF08192.11 KXG52455.1 - 0.21 10.0 22.1 0.3 9.5 22.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 Hydin_ADK PF17213.3 KXG52455.1 - 5 7.3 23.5 30 4.8 0.0 2.8 2 1 0 2 2 2 0 Hydin Adenylate kinase-like domain Ldh_1_C PF02866.18 KXG52456.1 - 1.8e-46 158.1 0.0 3.5e-46 157.2 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KXG52456.1 - 1.5e-42 145.1 0.0 2.7e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXG52456.1 - 0.00065 18.8 0.0 0.00091 18.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 KXG52456.1 - 0.0074 15.6 0.0 0.11 11.8 0.0 2.7 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 KXG52456.1 - 0.02 15.3 0.2 0.16 12.4 0.0 2.5 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain V-SNARE_C PF12352.8 KXG52457.1 - 6.1e-14 52.1 0.4 1.7e-13 50.6 0.2 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KXG52457.1 - 0.0009 19.1 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 Sec20 BAR_2 PF10455.9 KXG52457.1 - 0.029 13.5 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking She9_MDM33 PF05546.11 KXG52457.1 - 0.067 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family Sigma70_r4 PF04545.16 KXG52457.1 - 0.099 12.2 0.2 0.23 11.0 0.2 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Uso1_p115_C PF04871.13 KXG52457.1 - 0.15 12.4 0.8 0.32 11.4 0.8 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Pox_EPC_I2-L1 PF12575.8 KXG52457.1 - 0.19 12.0 0.1 1.9 8.8 0.0 2.1 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 DUF4407 PF14362.6 KXG52457.1 - 3.3 7.0 4.9 5.6 6.2 3.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF5353 PF17304.2 KXG52458.1 - 5.8e-34 115.7 2.1 7.7e-34 115.3 2.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5353) LCD1 PF09798.9 KXG52458.1 - 0.051 12.1 0.6 0.056 12.0 0.6 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Ferlin_C PF16165.5 KXG52458.1 - 0.12 12.4 1.3 0.17 11.8 1.3 1.3 1 0 0 1 1 1 0 Ferlin C-terminus 2-oxoacid_dh PF00198.23 KXG52459.1 - 5.9e-75 251.7 0.1 7.7e-75 251.3 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXG52459.1 - 4.5e-17 61.6 0.6 1.4e-16 60.0 0.3 2.1 1 1 1 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 KXG52459.1 - 5.4e-12 45.9 0.9 2.3e-11 43.9 0.5 2.3 2 0 0 2 2 2 1 e3 binding domain SopE_GEF PF07487.13 KXG52459.1 - 0.02 15.0 0.6 0.037 14.1 0.1 1.7 2 0 0 2 2 2 0 SopE GEF domain Sec7 PF01369.20 KXG52460.1 - 3.9e-69 232.0 0.5 1.3e-68 230.2 0.5 2.0 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KXG52460.1 - 4.7e-41 140.3 2.9 4.7e-41 140.3 2.9 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KXG52460.1 - 1.4e-34 117.8 6.8 1.2e-32 111.6 0.0 5.8 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 KXG52460.1 - 6.1e-17 61.8 4.7 8.2e-16 58.2 0.3 3.2 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 LTXXQ PF07813.12 KXG52460.1 - 0.48 11.2 4.1 2.6 8.8 0.2 3.7 3 0 0 3 3 3 0 LTXXQ motif family protein NAD_binding_7 PF13241.6 KXG52461.1 - 2.7e-32 111.3 0.1 4.3e-32 110.7 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KXG52461.1 - 4.8e-31 106.2 0.0 7.6e-31 105.6 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KXG52461.1 - 2.7e-14 52.3 0.0 2.7e-14 52.3 0.0 1.6 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 KXG52461.1 - 0.0043 16.3 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXG52461.1 - 0.0052 16.9 0.0 0.0082 16.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KXG52461.1 - 0.035 13.4 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain LSDAT_prok PF18171.1 KXG52461.1 - 0.039 13.2 0.1 0.059 12.6 0.1 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Pribosyltran_N PF13793.6 KXG52462.1 - 1.1e-44 151.1 0.1 2.9e-43 146.5 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KXG52462.1 - 3.8e-34 118.3 0.1 4.4e-29 101.8 0.1 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KXG52462.1 - 1.1e-07 31.5 0.1 0.00011 21.8 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain PLDc_2 PF13091.6 KXG52463.1 - 1.3e-16 60.7 0.1 4.9e-06 26.5 0.1 3.7 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KXG52463.1 - 3.7e-12 45.9 4.2 5.9e-07 29.4 0.3 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif RFX_DNA_binding PF02257.15 KXG52464.1 - 1.8e-27 95.7 0.1 4e-27 94.6 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain Sulfatase PF00884.23 KXG52465.1 - 5.8e-19 68.6 0.3 1.2e-18 67.6 0.3 1.6 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXG52465.1 - 0.00049 19.8 0.0 0.00083 19.0 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase 2OG-FeII_Oxy_3 PF13640.6 KXG52467.1 - 2.6e-07 31.4 0.0 5.4e-06 27.2 0.0 2.2 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily UDPG_MGDP_dh_N PF03721.14 KXG52469.1 - 2.5e-51 173.9 0.2 2.6e-32 111.9 0.2 2.6 2 1 1 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KXG52469.1 - 1.3e-29 102.3 0.0 1.9e-28 98.5 0.0 2.6 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KXG52469.1 - 6e-21 74.8 0.0 1.2e-16 61.0 0.0 3.3 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 KXG52469.1 - 0.023 14.9 0.0 0.066 13.5 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KXG52469.1 - 0.053 13.7 0.0 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF3665 PF12427.8 KXG52469.1 - 1.3 8.8 7.1 0.45 10.2 0.4 2.6 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase TPT PF03151.16 KXG52470.1 - 7.9e-34 117.3 18.4 9.6e-34 117.0 18.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXG52470.1 - 8.2e-05 22.8 36.7 0.00019 21.6 15.4 2.3 2 0 0 2 2 2 2 EamA-like transporter family MFS_1 PF07690.16 KXG52472.1 - 3.2e-44 151.3 39.5 3.2e-44 151.3 39.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG52473.1 - 4e-112 375.3 28.2 4.9e-112 375.1 28.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG52473.1 - 6.9e-18 64.7 31.3 1.1e-14 54.2 7.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG52474.1 - 1.1e-99 334.3 31.6 1.3e-99 334.1 31.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG52474.1 - 1.1e-25 90.3 42.8 3.8e-20 72.1 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG52474.1 - 0.00011 20.8 0.7 0.00011 20.8 0.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ACOX PF01756.19 KXG52475.1 - 2.1e-48 164.3 0.1 1e-47 162.0 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KXG52475.1 - 8.9e-27 94.1 1.1 2.2e-26 92.9 1.1 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KXG52475.1 - 9.8e-13 48.1 0.0 4.7e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KXG52475.1 - 7e-05 23.1 0.4 0.065 13.4 0.0 2.5 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.16 KXG52476.1 - 5.7e-22 78.1 51.4 2.2e-15 56.4 25.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CPP1-like PF11833.8 KXG52476.1 - 0.19 11.3 4.7 0.65 9.6 4.7 2.0 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Glyco_hydro_43 PF04616.14 KXG52477.1 - 7.1e-66 222.5 4.1 9.8e-66 222.0 4.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXG52477.1 - 8.8e-37 126.8 0.0 1.4e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF3425 PF11905.8 KXG52477.1 - 5.4e-25 87.8 1.2 1.4e-24 86.5 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Wzy_C_2 PF11846.8 KXG52478.1 - 0.076 12.9 0.4 0.076 12.9 0.4 2.2 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal MFS_1 PF07690.16 KXG52478.1 - 3 6.7 17.5 8.6 5.2 11.4 2.2 1 1 1 2 2 2 0 Major Facilitator Superfamily DUF3176 PF11374.8 KXG52479.1 - 1.5e-33 115.2 2.3 3.5e-33 114.0 2.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Fungal_trans PF04082.18 KXG52480.1 - 2.1e-27 95.8 0.0 3.3e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG52480.1 - 1.7e-11 44.0 5.4 3.3e-11 43.1 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ArsB PF02040.15 KXG52481.1 - 2.1e-09 37.2 24.0 2.4e-06 27.2 10.7 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein DUF1682 PF07946.14 KXG52481.1 - 0.35 10.0 4.6 0.62 9.2 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ATP-synt_E PF05680.12 KXG52481.1 - 5 7.5 9.4 2.3 8.6 5.4 2.3 2 0 0 2 2 2 0 ATP synthase E chain DDRGK PF09756.9 KXG52481.1 - 7.5 6.1 12.4 13 5.3 12.4 1.3 1 0 0 1 1 1 0 DDRGK domain Cupin_2 PF07883.11 KXG52482.1 - 1.5e-24 85.5 0.4 4e-15 55.3 0.2 2.2 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KXG52482.1 - 7.8e-05 22.6 0.1 0.021 14.7 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 KXG52482.1 - 0.00029 21.0 0.0 0.0027 17.9 0.0 2.1 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_3 PF05899.12 KXG52482.1 - 0.0026 17.4 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) ARD PF03079.14 KXG52482.1 - 0.03 14.5 0.2 0.09 13.0 0.0 1.8 2 0 0 2 2 2 0 ARD/ARD' family FAD_binding_3 PF01494.19 KXG52483.1 - 1.7e-20 73.6 0.0 2.8e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG52483.1 - 2.2e-09 37.0 0.1 6.2e-05 22.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG52483.1 - 4.2e-08 33.2 3.6 0.00048 19.8 3.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG52483.1 - 1.5e-07 31.5 0.5 4.4e-07 30.0 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXG52483.1 - 2.6e-06 26.8 1.5 4.4e-06 26.0 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXG52483.1 - 1.4e-05 24.0 1.4 8e-05 21.5 1.4 1.8 1 1 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 KXG52483.1 - 5e-05 22.3 0.8 0.0076 15.1 0.0 2.8 2 1 1 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 KXG52483.1 - 7.2e-05 23.3 0.0 0.00025 21.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXG52483.1 - 0.00063 18.9 1.3 0.0051 15.9 1.3 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KXG52483.1 - 0.00069 18.8 0.7 0.0012 18.0 0.7 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KXG52483.1 - 0.0026 17.1 0.4 0.085 12.1 0.2 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 KXG52483.1 - 0.022 14.0 1.2 0.11 11.7 0.6 2.0 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.18 KXG52483.1 - 0.025 14.5 0.3 0.041 13.8 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KXG52483.1 - 0.045 13.1 3.8 0.068 12.5 3.8 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXG52483.1 - 0.11 12.1 0.8 0.18 11.4 0.8 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.6 KXG52483.1 - 0.11 12.4 1.5 1.2 9.1 1.5 2.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding FAA_hydrolase PF01557.18 KXG52484.1 - 1.2e-59 201.6 0.0 1.6e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Barwin PF00967.17 KXG52485.1 - 0.0033 17.3 2.3 0.0035 17.2 0.4 2.0 2 0 0 2 2 2 1 Barwin family BPL_C PF02237.17 KXG52485.1 - 0.16 11.9 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain DUF4772 PF15997.5 KXG52485.1 - 1.1 9.9 3.9 9.8 6.8 3.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4772) Glyco_transf_25 PF01755.17 KXG52486.1 - 0.0054 16.6 0.0 0.013 15.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DAP_epimerase PF01678.19 KXG52486.1 - 0.028 14.6 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 Diaminopimelate epimerase Ribosomal_S11 PF00411.19 KXG52486.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S11 Ribonuc_red_lgC PF02867.15 KXG52487.1 - 7.2e-184 612.2 0.0 1.1e-183 611.6 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KXG52487.1 - 5.6e-22 77.5 0.0 1.2e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KXG52487.1 - 4.5e-15 56.0 0.0 1.2e-14 54.7 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain TraT PF05818.12 KXG52488.1 - 0.74 9.5 5.2 0.24 11.0 2.7 1.4 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Fungal_trans_2 PF11951.8 KXG52489.1 - 1.9e-06 27.0 0.1 4e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KXG52490.1 - 1.1e-21 77.2 0.0 9.3e-17 61.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXG52490.1 - 2.3e-09 37.1 0.0 2.2e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG52490.1 - 6.5e-08 32.7 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 KR domain PRK PF00485.18 KXG52491.1 - 0.00017 21.4 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KXG52491.1 - 0.025 13.8 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 KXG52491.1 - 0.059 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 KXG52491.1 - 0.091 13.3 0.2 0.32 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KXG52491.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 KXG52491.1 - 0.14 11.4 0.1 0.29 10.4 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Mur_ligase_M PF08245.12 KXG52493.1 - 6.9e-07 29.4 0.2 1.4e-06 28.4 0.2 1.5 1 1 0 1 1 1 1 Mur ligase middle domain Pkinase PF00069.25 KXG52494.1 - 1.4e-59 201.7 0.0 5.2e-37 127.7 0.0 2.9 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG52494.1 - 5.9e-43 147.0 0.0 4.8e-25 88.3 0.0 2.5 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXG52494.1 - 0.085 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Adaptin_N PF01602.20 KXG52494.1 - 0.14 10.7 3.6 2 6.9 1.2 2.8 3 0 0 3 3 3 0 Adaptin N terminal region Exo70 PF03081.15 KXG52494.1 - 0.71 8.9 5.0 3.4 6.6 0.4 3.0 3 0 0 3 3 3 0 Exo70 exocyst complex subunit ABC1 PF03109.16 KXG52495.1 - 2.6e-33 114.7 0.0 4.5e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 KXG52495.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Oxygenase-NA PF09859.9 KXG52495.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA RAP1 PF07218.11 KXG52495.1 - 7.4 4.7 7.0 15 3.7 6.8 1.5 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NifU_N PF01592.16 KXG52496.1 - 7e-54 181.4 0.1 9.1e-54 181.0 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain YCII PF03795.14 KXG52497.1 - 6.3e-09 36.1 0.0 7.8e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Beta-lactamase PF00144.24 KXG52498.1 - 1.7e-27 96.6 0.0 2.4e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Zn_clus PF00172.18 KXG52499.1 - 0.016 15.3 16.1 0.027 14.6 16.1 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Anp1 PF03452.14 KXG52500.1 - 9.8e-108 359.5 0.0 1.2e-107 359.3 0.0 1.1 1 0 0 1 1 1 1 Anp1 CENP-U PF13097.6 KXG52501.1 - 1 9.3 10.0 0.04 13.9 1.6 2.2 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit DivIC PF04977.15 KXG52501.1 - 4.9 7.0 7.5 16 5.3 7.5 1.7 1 1 0 1 1 1 0 Septum formation initiator Ecm33 PF12454.8 KXG52502.1 - 1.2e-13 51.0 0.4 1.2e-13 51.0 0.4 3.1 2 2 2 4 4 4 1 GPI-anchored cell wall organization protein LRR_5 PF13306.6 KXG52502.1 - 2.4e-06 27.5 0.1 0.12 12.4 0.1 2.6 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Recep_L_domain PF01030.24 KXG52502.1 - 2.1e-05 24.6 2.4 0.28 11.3 1.1 4.4 1 1 3 5 5 5 1 Receptor L domain SR-25 PF10500.9 KXG52502.1 - 1.6 8.3 6.0 2.3 7.8 6.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 KXG52502.1 - 3.8 5.7 4.7 5.8 5.1 4.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HhH-GPD PF00730.25 KXG52503.1 - 9e-14 51.8 0.0 1.5e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein IGR PF09597.10 KXG52503.1 - 0.066 13.3 0.0 0.6 10.3 0.0 2.3 2 0 0 2 2 2 0 IGR protein motif RuvB_C PF05491.13 KXG52503.1 - 0.18 11.7 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain UCR_14kD PF02271.16 KXG52504.1 - 1.1e-43 147.2 0.1 1.3e-43 147.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Ferritin PF00210.24 KXG52504.1 - 0.011 15.6 0.0 0.08 12.9 0.0 1.9 1 1 1 2 2 2 0 Ferritin-like domain Mito_carr PF00153.27 KXG52505.1 - 8.8e-65 214.7 2.9 1.5e-22 79.4 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein APH PF01636.23 KXG52506.1 - 7.2e-07 29.4 0.1 0.0099 15.8 0.0 2.2 2 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KXG52506.1 - 0.19 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain adh_short PF00106.25 KXG52507.1 - 1.1e-17 64.1 0.0 7e-17 61.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG52507.1 - 8.9e-08 32.0 0.0 1.6e-06 27.9 0.0 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG52507.1 - 4.7e-06 26.6 0.1 1.7e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 KR domain DUF3632 PF12311.8 KXG52508.1 - 1.8e-30 106.7 1.2 2.4e-30 106.2 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Octopine_DH PF02317.17 KXG52508.1 - 0.03 14.4 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain G-patch PF01585.23 KXG52510.1 - 1.3e-09 37.8 0.5 3.1e-09 36.6 0.5 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KXG52510.1 - 0.00016 21.4 0.0 0.00055 19.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 KXG52510.1 - 0.023 14.8 0.3 0.023 14.8 0.3 2.3 3 0 0 3 3 3 0 G-patch domain HypA PF01155.19 KXG52511.1 - 0.16 12.0 1.7 0.3 11.1 1.7 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA UQ_con PF00179.26 KXG52512.1 - 1.7e-42 144.4 0.0 1.8e-31 108.7 0.1 2.0 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Asn_synthase PF00733.21 KXG52513.1 - 5.8e-95 318.9 0.5 2.8e-55 188.4 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KXG52513.1 - 2.3e-39 134.1 0.0 4e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXG52513.1 - 8.5e-30 103.7 0.0 1.7e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXG52513.1 - 2.8e-06 26.9 0.0 5.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KXG52513.1 - 0.0046 16.1 0.0 0.0069 15.5 0.0 1.4 1 1 0 1 1 1 1 NAD synthase Porin_3 PF01459.22 KXG52514.1 - 7.8e-71 238.7 6.0 3.6e-58 197.2 2.4 2.0 2 0 0 2 2 2 2 Eukaryotic porin DnaJ PF00226.31 KXG52515.1 - 5e-22 77.8 0.1 8.3e-22 77.1 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Ank_2 PF12796.7 KXG52516.1 - 4.1e-23 81.8 3.7 4.2e-09 36.9 0.2 4.2 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG52516.1 - 7e-14 52.0 7.3 0.00073 20.1 0.0 6.2 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG52516.1 - 6.1e-13 47.7 7.3 2.3 9.1 0.0 7.7 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KXG52516.1 - 3.3e-10 39.9 6.5 2.5 8.7 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KXG52516.1 - 1.9e-09 37.6 5.7 0.054 13.8 0.2 7.2 3 1 4 7 7 7 3 Ankyrin repeats (many copies) F-box-like PF12937.7 KXG52516.1 - 0.0052 16.7 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXG52516.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 F-box domain Ank_2 PF12796.7 KXG52517.1 - 3e-36 123.9 10.0 1.2e-08 35.4 0.0 7.8 4 2 5 9 9 9 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG52517.1 - 4.4e-21 72.7 24.8 0.00044 20.5 0.1 14.1 16 0 0 16 16 16 6 Ankyrin repeat Ank_4 PF13637.6 KXG52517.1 - 1.1e-20 73.7 16.1 1.4e-05 25.5 0.1 10.6 7 3 6 13 13 13 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG52517.1 - 3.8e-14 52.6 15.5 5.7e-05 23.3 0.0 8.8 6 4 4 10 10 10 4 Ankyrin repeats (many copies) Ank PF00023.30 KXG52517.1 - 3.3e-12 46.3 20.9 0.33 11.5 0.0 11.7 12 0 0 12 12 12 3 Ankyrin repeat F-box-like PF12937.7 KXG52517.1 - 0.091 12.7 5.0 0.25 11.2 0.6 2.7 2 0 0 2 2 2 0 F-box-like Peptidase_M24 PF00557.24 KXG52518.1 - 7.2e-43 146.7 0.0 9.1e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 LZ_Tnp_IS66 PF13007.7 KXG52518.1 - 0.61 10.9 2.9 1.3 9.9 2.9 1.5 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain FA_desaturase PF00487.24 KXG52519.1 - 1.4e-24 87.3 10.1 2e-24 86.8 10.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KXG52519.1 - 4.1e-18 64.6 0.2 7.2e-18 63.8 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.26 KXG52520.1 - 6.6e-25 87.1 0.1 1.3e-24 86.1 0.1 1.5 1 1 0 1 1 1 1 MSP (Major sperm protein) domain ATG16 PF08614.11 KXG52520.1 - 0.0041 17.4 0.5 0.0057 16.9 0.5 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ASH PF15780.5 KXG52520.1 - 0.026 14.7 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF756 PF05506.12 KXG52520.1 - 0.11 13.4 0.0 0.23 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF756) FixG_C PF11614.8 KXG52520.1 - 0.16 12.2 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase UBA PF00627.31 KXG52521.1 - 6.6e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.20 KXG52521.1 - 0.0037 17.4 1.3 0.0064 16.7 0.0 2.2 3 0 0 3 3 3 1 UBX domain CDC27 PF09507.10 KXG52521.1 - 2 7.7 35.7 1 8.7 34.0 1.3 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 V_ATPase_I PF01496.19 KXG52521.1 - 2.8 5.7 8.5 3.1 5.6 8.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 KXG52521.1 - 9.8 5.0 9.0 13 4.6 9.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Rad52_Rad22 PF04098.15 KXG52522.1 - 5.6e-61 205.0 0.1 7.3e-61 204.6 0.1 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Aa_trans PF01490.18 KXG52523.1 - 1.3e-74 251.4 28.9 1.6e-74 251.1 28.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TatD_DNase PF01026.21 KXG52525.1 - 3.5e-43 147.8 0.0 4.2e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase FMN_dh PF01070.18 KXG52527.1 - 2e-115 385.6 0.0 2.4e-115 385.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXG52527.1 - 4.2e-18 65.3 0.1 9.1e-18 64.2 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXG52527.1 - 7.6e-05 22.0 0.1 0.00015 21.1 0.1 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXG52527.1 - 0.0041 16.2 0.1 0.011 14.7 0.1 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KXG52527.1 - 0.0079 15.5 0.0 1.5 8.1 0.0 2.5 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 KXG52527.1 - 0.011 15.2 0.0 0.073 12.5 0.0 1.9 1 1 1 2 2 2 0 Nitronate monooxygenase Nup54_C PF18437.1 KXG52527.1 - 0.18 11.7 0.1 0.36 10.8 0.1 1.4 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain zf-BED PF02892.15 KXG52529.1 - 0.015 15.3 1.9 0.025 14.6 1.9 1.3 1 0 0 1 1 1 0 BED zinc finger Asp PF00026.23 KXG52530.1 - 1.7e-72 244.6 4.9 2.3e-72 244.1 4.9 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXG52530.1 - 3.4e-10 40.4 7.0 6.2e-07 29.8 3.9 3.4 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXG52530.1 - 8.1e-05 23.2 0.0 0.074 13.7 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KXG52530.1 - 0.0016 18.2 0.0 0.0068 16.2 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KXG52530.1 - 0.053 14.1 0.0 5.7 7.6 0.0 2.8 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF515 PF04415.12 KXG52530.1 - 1.3 7.3 4.9 1.9 6.8 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) FMN_dh PF01070.18 KXG52531.1 - 5.3e-104 348.0 0.0 6e-104 347.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXG52531.1 - 6.2e-05 22.2 0.2 0.00013 21.1 0.2 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXG52531.1 - 0.0011 18.1 0.1 0.0015 17.7 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KXG52531.1 - 0.0041 16.6 0.8 0.08 12.4 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 KXG52531.1 - 0.055 12.8 0.4 0.47 9.7 0.4 2.0 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG PPTA PF01239.22 KXG52531.1 - 0.066 13.0 0.0 0.19 11.5 0.0 1.9 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat 4HBT PF03061.22 KXG52532.1 - 0.046 14.1 0.0 8.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Thioesterase superfamily zf-C2H2 PF00096.26 KXG52533.1 - 0.013 15.9 22.7 0.044 14.3 1.8 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-FCS PF06467.14 KXG52533.1 - 0.027 14.4 2.2 3.3 7.7 0.2 2.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-CHCC PF10276.9 KXG52533.1 - 0.4 10.8 4.1 6 7.0 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger domain PyrI_C PF02748.15 KXG52533.1 - 0.68 9.9 3.3 3.1 7.8 0.3 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DZR PF12773.7 KXG52533.1 - 3.1 7.9 9.1 1.8 8.6 0.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2_4 PF13894.6 KXG52533.1 - 4.6 8.3 22.2 7.2 7.7 2.5 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger DSPc PF00782.20 KXG52534.1 - 3.7e-25 88.3 0.0 5.3e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KXG52534.1 - 0.0037 17.6 0.0 0.0064 16.8 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KXG52534.1 - 0.093 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Vfa1 PF08432.10 KXG52535.1 - 1.2e-60 205.0 14.7 1.3e-60 204.8 14.7 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 MTBP_N PF14918.6 KXG52535.1 - 0.016 14.7 0.9 0.027 14.0 0.9 1.2 1 0 0 1 1 1 0 MDM2-binding RR_TM4-6 PF06459.12 KXG52535.1 - 0.035 13.9 10.7 0.048 13.5 10.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KXG52535.1 - 0.045 12.0 9.7 0.044 12.1 9.7 1.0 1 0 0 1 1 1 0 CDC45-like protein U79_P34 PF03064.16 KXG52535.1 - 0.066 12.6 11.7 0.091 12.1 11.7 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4228 PF14009.6 KXG52535.1 - 0.09 13.2 3.6 0.12 12.7 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF2201_N PF13203.6 KXG52535.1 - 0.25 10.9 4.0 0.38 10.3 4.0 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain HCMV_UL139 PF12507.8 KXG52535.1 - 0.29 11.5 5.3 0.54 10.7 5.3 1.5 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein NARP1 PF12569.8 KXG52535.1 - 3.2 6.6 17.4 4.1 6.2 17.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PPL5 PF18168.1 KXG52535.1 - 3.7 6.7 8.7 4.8 6.4 8.7 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Presenilin PF01080.17 KXG52535.1 - 4.4 6.0 10.1 5.3 5.7 10.1 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 KXG52535.1 - 4.8 7.2 5.4 5.6 7.0 5.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ATP11 PF06644.11 KXG52535.1 - 5.9 6.6 11.6 7.4 6.3 11.6 1.2 1 0 0 1 1 1 0 ATP11 protein Ndc1_Nup PF09531.10 KXG52536.1 - 7.5e-165 550.1 1.5 8.4e-165 549.9 1.5 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.6 KXG52537.1 - 9.8e-26 90.1 3.0 9.8e-26 90.1 3.0 2.6 3 1 0 3 3 2 1 Syntaxin-like protein SNARE PF05739.19 KXG52537.1 - 5.8e-12 45.4 2.0 5.8e-12 45.4 2.0 1.8 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KXG52537.1 - 7.5e-06 25.8 13.0 5.3e-05 23.0 13.0 2.2 1 1 0 1 1 1 1 Syntaxin Synaptobrevin PF00957.21 KXG52537.1 - 0.0034 17.2 1.0 0.012 15.4 0.6 2.1 2 0 0 2 2 2 1 Synaptobrevin Nre_C PF04895.12 KXG52537.1 - 0.026 14.5 0.4 0.1 12.6 0.1 2.1 2 0 0 2 2 2 0 Archaeal Nre, C-terminal DUF883 PF05957.13 KXG52537.1 - 0.15 12.7 10.0 0.17 12.5 0.1 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.11 KXG52537.1 - 0.15 10.0 6.5 0.26 9.2 6.5 1.4 1 1 0 1 1 1 0 Prominin T3SSipB PF16535.5 KXG52537.1 - 0.33 11.4 6.9 0.91 10.0 2.9 2.7 3 0 0 3 3 3 0 Type III cell invasion protein SipB DUF3333 PF11812.8 KXG52537.1 - 0.99 9.6 5.5 10 6.3 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) DUF1664 PF07889.12 KXG52537.1 - 1.4 9.0 5.7 17 5.5 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) LPP PF04728.13 KXG52537.1 - 3.4 8.1 6.2 7 7.1 0.1 3.6 3 1 0 3 3 3 0 Lipoprotein leucine-zipper DUF5345 PF17280.2 KXG52537.1 - 5.5 7.0 7.6 1.8 8.6 0.1 3.1 3 1 0 3 3 3 0 Family of unknown function (DUF5345) Cyto_heme_lyase PF01265.17 KXG52538.1 - 8.8e-39 133.8 7.0 1.4e-34 120.0 0.4 3.3 1 1 0 2 2 2 2 Cytochrome c/c1 heme lyase MDD_C PF18376.1 KXG52539.1 - 1.3e-66 223.9 0.0 1.8e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KXG52539.1 - 8.1e-10 38.8 0.4 2.3e-09 37.4 0.4 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Pyrid_oxidase_2 PF13883.6 KXG52539.1 - 0.14 12.1 0.1 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase IKI3 PF04762.12 KXG52540.1 - 0 1040.2 0.0 0 1039.8 0.0 1.1 1 0 0 1 1 1 1 IKI3 family UME PF08064.13 KXG52540.1 - 0.13 12.2 0.2 5.8 6.9 0.0 3.1 3 0 0 3 3 3 0 UME (NUC010) domain COX7C PF02935.16 KXG52541.1 - 1.3e-22 79.8 4.2 1.6e-22 79.5 4.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.6 KXG52542.1 - 4.6e-90 302.2 0.8 7.4e-90 301.5 0.1 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 KXG52542.1 - 4.8e-55 185.7 3.7 6.3e-55 185.3 2.4 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 KXG52542.1 - 6.9e-18 65.0 0.4 2.1e-17 63.4 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG52542.1 - 1.5e-06 28.5 0.0 6.1e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG52542.1 - 7.2e-05 22.9 0.0 0.00023 21.2 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KXG52542.1 - 0.012 14.7 0.0 0.033 13.2 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 KXG52542.1 - 0.063 13.6 0.1 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KXG52542.1 - 0.13 12.2 1.4 0.23 11.3 0.0 2.2 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea ABC_tran_CTD PF16326.5 KXG52542.1 - 0.41 10.9 2.7 2.7 8.3 0.7 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain Cut8 PF08559.10 KXG52543.1 - 9.8e-81 270.9 0.0 1.2e-80 270.6 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein DUF3984 PF13136.6 KXG52544.1 - 2e-87 293.7 23.6 3.1e-87 293.1 23.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) FAD_binding_3 PF01494.19 KXG52544.1 - 7.4e-15 55.0 0.0 2.2e-14 53.5 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KXG52544.1 - 0.028 13.5 0.0 2.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_8 PF13450.6 KXG52544.1 - 0.078 13.2 0.4 0.28 11.5 0.4 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain OTCace PF00185.24 KXG52545.1 - 2.4e-45 154.4 0.0 3.6e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KXG52545.1 - 2.5e-45 154.1 0.1 4.5e-45 153.3 0.1 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF3712 PF12505.8 KXG52546.1 - 0.00012 22.4 0.3 0.004 17.4 0.2 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KXG52546.1 - 0.00074 20.0 0.4 0.54 10.8 0.0 4.0 5 0 0 5 5 5 2 Late embryogenesis abundant protein ALS_ss_C PF10369.9 KXG52547.1 - 5.2e-15 55.4 0.0 7.6e-14 51.7 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KXG52547.1 - 8.9e-13 47.8 0.1 1.6e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KXG52547.1 - 7e-08 32.2 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KXG52547.1 - 0.045 13.8 0.1 7.9 6.5 0.0 2.5 2 0 0 2 2 2 0 ACT domain KH_1 PF00013.29 KXG52548.1 - 9.3e-10 38.2 0.0 4.9e-06 26.3 0.0 2.7 2 0 0 2 2 2 2 KH domain Helicase_C PF00271.31 KXG52549.1 - 1.7e-15 57.3 0.0 1.4e-11 44.7 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KXG52549.1 - 9.3e-07 29.5 2.4 9.3e-07 29.5 2.4 2.0 2 0 0 2 2 2 1 RecQ zinc-binding PPR_2 PF13041.6 KXG52550.1 - 7e-11 42.2 0.0 0.00079 19.6 0.0 3.7 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.20 KXG52550.1 - 2.5e-06 27.3 0.7 0.03 14.6 0.0 4.2 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 KXG52550.1 - 0.0073 15.7 0.0 0.033 13.6 0.0 2.0 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KXG52550.1 - 0.012 16.3 0.0 2.3 9.2 0.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.6 KXG52550.1 - 0.15 12.2 0.0 62 3.8 0.0 3.2 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR_1 PF12854.7 KXG52550.1 - 0.19 11.5 0.0 5.6 6.7 0.0 2.7 3 0 0 3 3 3 0 PPR repeat MRP-S25 PF13741.6 KXG52551.1 - 1.3e-84 283.4 4.4 1.4e-84 283.2 4.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KXG52551.1 - 0.044 14.0 0.7 5.7 7.2 0.7 2.5 1 1 0 1 1 1 0 Mitochondrial ribosomal protein S23 SOG2 PF10428.9 KXG52552.1 - 1.5e-101 341.2 0.1 3.4e-52 178.3 0.1 4.1 3 1 1 4 4 4 2 RAM signalling pathway protein LRR_8 PF13855.6 KXG52552.1 - 1.6e-15 56.6 17.9 7.1e-10 38.5 3.8 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KXG52552.1 - 2.3e-13 50.1 3.4 1.4e-06 28.5 1.3 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXG52552.1 - 0.0018 18.6 1.9 21 6.1 0.2 5.0 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_9 PF14580.6 KXG52552.1 - 0.012 15.1 0.4 0.025 14.1 0.4 1.5 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 KXG52552.1 - 0.21 11.7 6.5 17 5.8 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat Cofilin_ADF PF00241.20 KXG52553.1 - 2.1e-24 85.7 0.2 2.6e-24 85.4 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ank_2 PF12796.7 KXG52554.1 - 6.9e-96 315.0 11.0 4.9e-13 49.5 0.0 14.9 7 3 7 15 15 15 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG52554.1 - 5.5e-67 221.3 23.2 8.5e-05 23.0 0.0 17.7 11 4 5 17 17 17 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG52554.1 - 4.2e-47 152.6 25.6 0.012 16.1 0.0 21.2 22 0 0 22 22 21 9 Ankyrin repeat Ank_5 PF13857.6 KXG52554.1 - 9.1e-44 147.0 28.9 1.2e-05 25.5 0.0 17.2 10 4 9 19 19 18 12 Ankyrin repeats (many copies) Ank PF00023.30 KXG52554.1 - 6.2e-41 137.1 45.5 0.0035 17.7 0.1 23.2 25 0 0 25 25 25 8 Ankyrin repeat NACHT PF05729.12 KXG52554.1 - 1.5e-09 38.0 0.2 8.7e-08 32.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain NACHT_N PF17100.5 KXG52554.1 - 4.1e-08 33.3 0.0 9.8e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_16 PF13191.6 KXG52554.1 - 2.4e-05 24.8 0.0 0.00019 21.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXG52554.1 - 0.0018 18.6 0.0 0.016 15.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXG52554.1 - 0.019 15.4 0.1 0.13 12.6 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KXG52554.1 - 0.069 12.9 0.1 0.48 10.1 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase VWA_3_C PF18571.1 KXG52554.1 - 3.9 7.4 4.8 7.3 6.5 0.0 4.1 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain Peptidase_S10 PF00450.22 KXG52555.1 - 8e-74 249.5 0.1 2.4e-73 248.0 0.1 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase Tcp11 PF05794.13 KXG52556.1 - 2.5e-117 392.7 0.2 3.1e-117 392.4 0.2 1.0 1 0 0 1 1 1 1 T-complex protein 11 Peptidase_M75 PF09375.10 KXG52556.1 - 0.00077 19.0 0.1 0.0013 18.3 0.1 1.2 1 0 0 1 1 1 1 Imelysin Ydc2-catalyt PF09159.10 KXG52557.1 - 3.2e-87 292.8 0.0 6.5e-87 291.8 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.27 KXG52557.1 - 6.9e-05 22.5 0.1 0.00016 21.3 0.1 1.6 1 0 0 1 1 1 1 SAP domain Pox_A22 PF04848.13 KXG52557.1 - 0.00034 20.7 0.0 1.7 8.8 0.0 3.7 4 0 0 4 4 4 2 Poxvirus A22 protein CTP_transf_like PF01467.26 KXG52559.1 - 7.2e-05 23.0 0.1 0.00032 20.9 0.0 1.9 2 1 0 2 2 2 1 Cytidylyltransferase-like Aim19 PF10315.9 KXG52560.1 - 0.0025 18.1 0.0 0.0031 17.8 0.0 1.3 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF4536 PF15055.6 KXG52560.1 - 0.0077 16.4 0.6 0.016 15.4 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) DUF1977 PF09320.11 KXG52561.1 - 2.2e-31 108.2 0.0 5.1e-31 107.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KXG52561.1 - 3.6e-22 78.3 0.6 7.7e-22 77.2 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain Ufd2P_core PF10408.9 KXG52562.1 - 1.1e-218 727.9 10.1 1.3e-218 727.6 10.1 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KXG52562.1 - 6e-26 90.4 0.4 1.8e-25 88.9 0.4 1.9 1 0 0 1 1 1 1 U-box domain Steroid_dh PF02544.16 KXG52562.1 - 2.6e-14 53.5 0.2 3e-06 27.3 0.2 3.7 3 0 0 3 3 3 3 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KXG52562.1 - 0.00039 20.0 0.2 0.038 13.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1295) Tyrosinase PF00264.20 KXG52564.1 - 3.1e-55 187.9 0.0 4.2e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Metallophos PF00149.28 KXG52565.1 - 2.6e-12 47.7 2.1 4.1e-12 47.0 2.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PRTase_3 PF15610.6 KXG52566.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.5 2 0 0 2 2 2 0 PRTase ComF-like TMA7 PF09072.10 KXG52566.1 - 0.23 12.3 0.3 0.23 12.3 0.3 3.3 3 0 0 3 3 3 0 Translation machinery associated TMA7 PBP_N PF17093.5 KXG52566.1 - 0.99 9.7 6.2 0.54 10.5 0.4 2.7 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Exonuc_VII_L PF02601.15 KXG52566.1 - 5.2 6.5 10.5 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Meth_synt_2 PF01717.18 KXG52567.1 - 1.2e-148 494.7 0.0 5.1e-145 482.8 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KXG52567.1 - 1.6e-119 399.1 0.1 7e-113 377.3 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KXG52567.1 - 0.0019 17.4 0.2 0.06 12.5 0.0 3.1 3 1 0 3 3 3 1 Uroporphyrinogen decarboxylase (URO-D) SHOCT PF09851.9 KXG52567.1 - 0.52 10.1 3.6 0.47 10.3 0.1 2.7 3 0 0 3 3 3 0 Short C-terminal domain AA_permease_2 PF13520.6 KXG52568.1 - 2.3e-37 128.8 48.2 2.8e-37 128.6 48.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG52568.1 - 3.2e-18 65.6 42.3 4.1e-18 65.2 42.3 1.1 1 0 0 1 1 1 1 Amino acid permease M20_dimer PF07687.14 KXG52569.1 - 3.3e-19 68.8 0.0 1.2e-18 67.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KXG52569.1 - 1.5e-15 57.5 0.0 1.5e-14 54.2 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KXG52569.1 - 0.00032 20.5 0.0 0.00054 19.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 adh_short_C2 PF13561.6 KXG52570.1 - 1.4e-43 149.2 0.0 4e-43 147.7 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG52570.1 - 6.1e-23 81.3 0.0 1.3e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase MFS_1 PF07690.16 KXG52570.1 - 8.2e-14 51.3 25.1 8.2e-14 51.3 25.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily KR PF08659.10 KXG52570.1 - 0.0034 17.3 0.0 0.0068 16.3 0.0 1.5 1 0 0 1 1 1 1 KR domain SLATT_fungal PF18142.1 KXG52570.1 - 0.034 14.1 0.2 0.034 14.1 0.2 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Epimerase PF01370.21 KXG52570.1 - 0.16 11.4 0.0 3.4 7.0 0.0 2.4 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Wzz PF02706.15 KXG52570.1 - 0.97 9.8 5.4 1.1 9.6 0.2 3.0 3 0 0 3 3 3 0 Chain length determinant protein zf-met2 PF12907.7 KXG52571.1 - 8e-18 64.3 0.6 1.3e-17 63.6 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KXG52571.1 - 9.5e-07 29.6 11.3 1.5e-06 28.9 11.3 1.3 1 0 0 1 1 1 1 4F5 protein family Glyco_hydro_72 PF03198.14 KXG52572.1 - 2.7e-118 394.8 6.5 4.4e-118 394.1 6.5 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KXG52572.1 - 5.4e-26 91.1 6.3 1.6e-25 89.6 6.3 1.9 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 KXG52572.1 - 0.00031 20.3 0.0 0.0058 16.1 0.0 2.1 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KXG52572.1 - 0.015 14.4 1.1 0.1 11.7 1.1 2.3 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Peripla_BP_4 PF13407.6 KXG52572.1 - 0.088 12.4 0.0 6 6.4 0.0 2.3 2 0 0 2 2 2 0 Periplasmic binding protein domain Gly_transf_sug PF04488.15 KXG52573.1 - 1.5e-07 32.0 0.0 3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF1678 PF07913.11 KXG52573.1 - 0.042 13.6 0.3 0.98 9.1 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1678) Caps_synth PF05704.12 KXG52573.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Mucin PF01456.17 KXG52573.1 - 4.4 7.3 15.2 0.23 11.5 6.6 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein B_lectin PF01453.24 KXG52574.1 - 0.0054 17.2 0.0 1.1 9.8 0.0 2.5 1 1 1 2 2 2 2 D-mannose binding lectin DUF643 PF04867.12 KXG52574.1 - 0.19 12.4 0.0 0.29 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF643) SKG6 PF08693.10 KXG52575.1 - 7.2e-06 25.3 0.1 1.8e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 KXG52575.1 - 0.0056 16.8 1.8 0.015 15.4 1.8 1.7 1 1 1 2 2 2 1 Podoplanin TAL_FSA PF00923.19 KXG52576.1 - 1.9e-35 122.6 0.1 2.6e-35 122.1 0.1 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DUF5060 PF16586.5 KXG52576.1 - 0.069 13.5 0.1 0.45 10.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5060) DUF1388 PF07142.12 KXG52577.1 - 0.022 14.7 10.4 0.041 13.8 7.0 2.5 2 0 0 2 2 2 0 Repeat of unknown function (DUF1388) SANT_DAMP1_like PF16282.5 KXG52578.1 - 3.7e-31 107.2 3.0 6.6e-31 106.3 3.0 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 KXG52578.1 - 7.7e-05 22.6 13.2 0.0047 16.8 12.0 3.2 1 1 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.6 KXG52578.1 - 0.067 13.5 0.0 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain EMP24_GP25L PF01105.24 KXG52579.1 - 4.7e-51 173.3 0.6 5.5e-51 173.1 0.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4271 PF14093.6 KXG52579.1 - 0.12 12.3 0.9 8.4 6.2 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) Sugar_tr PF00083.24 KXG52580.1 - 6.2e-81 272.6 28.1 7.4e-81 272.3 28.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG52580.1 - 1.4e-22 80.1 35.5 2.2e-16 59.7 6.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG52580.1 - 3.2e-07 29.2 2.6 3.2e-07 29.2 2.6 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ICAM_N PF03921.14 KXG52580.1 - 0.12 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain Pam17 PF08566.10 KXG52580.1 - 0.18 11.6 0.9 0.6 9.9 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Glyco_hydro_1 PF00232.18 KXG52581.1 - 5.7e-150 499.7 0.1 7.3e-150 499.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Fungal_trans PF04082.18 KXG52581.1 - 5.3e-09 35.5 0.4 1.6e-07 30.6 0.1 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG52581.1 - 4e-05 23.6 15.0 7.2e-05 22.8 15.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_cc PF11790.8 KXG52581.1 - 0.0016 18.1 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core HATPase_c PF02518.26 KXG52583.1 - 7.9e-22 77.9 0.0 1.7e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXG52583.1 - 5.6e-17 61.9 1.0 5.2e-05 23.4 0.1 3.7 2 1 1 3 3 3 3 Response regulator receiver domain HisKA PF00512.25 KXG52583.1 - 0.00017 21.5 0.0 0.00061 19.8 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain NAD_Gly3P_dh_N PF01210.23 KXG52583.1 - 0.22 11.5 0.0 0.48 10.4 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus EHN PF06441.12 KXG52584.1 - 3.1e-33 114.4 1.2 6.2e-32 110.2 0.2 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXG52584.1 - 2.6e-16 60.1 0.1 6.6e-16 58.7 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG52584.1 - 0.00069 20.3 1.0 0.0014 19.3 1.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Proteasome PF00227.26 KXG52585.1 - 4e-41 140.6 0.0 4.7e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.8 KXG52586.1 - 3.2e-24 84.9 0.1 6.7e-24 83.9 0.1 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 KXG52586.1 - 0.0043 17.2 0.0 0.017 15.3 0.0 2.1 2 0 0 2 2 2 1 UBX domain NatB_MDM20 PF09797.9 KXG52587.1 - 6.7e-92 308.4 0.0 1.3e-91 307.5 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Ribosomal_L36e PF01158.18 KXG52587.1 - 4.9e-34 116.5 5.0 4.9e-34 116.5 5.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L36e TPR_19 PF14559.6 KXG52587.1 - 0.00043 20.7 0.2 0.02 15.4 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat RNA_polI_A34 PF08208.11 KXG52587.1 - 0.093 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CHCH PF06747.13 KXG52588.1 - 8.1e-07 29.0 7.5 1.4e-06 28.2 7.5 1.5 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 KXG52588.1 - 0.0014 18.8 2.1 0.0022 18.2 2.1 1.4 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 KXG52588.1 - 0.099 13.0 4.1 0.24 11.7 3.5 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Meis_PKNOX_N PF16493.5 KXG52588.1 - 0.68 10.3 4.2 6.7 7.1 0.1 2.2 1 1 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 zf-C3HC4_4 PF15227.6 KXG52589.1 - 0.00023 21.3 4.5 0.00024 21.2 2.0 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KXG52589.1 - 0.00034 20.4 1.4 0.00034 20.4 1.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXG52589.1 - 0.0056 16.7 4.4 0.015 15.3 4.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXG52589.1 - 0.0096 15.8 1.2 0.0096 15.8 1.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXG52589.1 - 0.035 14.4 1.0 0.035 14.4 1.0 2.2 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 KXG52589.1 - 0.42 10.6 6.3 0.064 13.2 1.4 2.1 2 0 0 2 2 2 0 zinc-RING finger domain WD40 PF00400.32 KXG52590.1 - 1.5e-19 70.0 10.3 3.3e-06 27.7 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG52590.1 - 0.0091 16.3 0.0 0.03 14.6 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Astro_capsid_p PF12226.8 KXG52590.1 - 0.59 9.2 3.5 0.89 8.6 3.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Proteasome PF00227.26 KXG52591.1 - 2.3e-31 108.7 0.0 2.7e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit UCH PF00443.29 KXG52592.1 - 4.9e-22 78.7 0.0 1.5e-21 77.1 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KXG52592.1 - 2.5e-12 46.9 0.1 5.7e-12 45.8 0.1 1.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Glyco_hydro_2 PF00703.21 KXG52592.1 - 0.091 13.4 0.0 0.29 11.8 0.0 1.8 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 WD40 PF00400.32 KXG52594.1 - 1.1e-54 181.2 17.1 4.2e-07 30.6 0.0 13.8 12 2 0 12 12 12 9 WD domain, G-beta repeat Utp13 PF08625.11 KXG52594.1 - 1.9e-49 167.2 0.1 3e-49 166.6 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KXG52594.1 - 1.5e-12 47.6 0.2 0.13 12.6 0.0 7.7 5 1 4 9 9 9 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXG52594.1 - 0.00087 18.3 0.2 0.57 9.1 0.0 4.3 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KXG52594.1 - 0.0016 17.3 0.2 3.4 6.3 0.1 4.1 5 0 0 5 5 5 1 Nup133 N terminal like Nup160 PF11715.8 KXG52594.1 - 0.0023 16.7 6.7 3.5 6.1 0.1 5.4 3 3 3 7 7 7 2 Nucleoporin Nup120/160 Frtz PF11768.8 KXG52594.1 - 0.11 10.7 0.0 0.33 9.2 0.0 1.7 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF1699 PF08004.11 KXG52594.1 - 0.19 11.4 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) G-patch_2 PF12656.7 KXG52595.1 - 2.4e-24 85.2 0.1 2.4e-24 85.2 0.1 3.1 3 0 0 3 3 3 1 G-patch domain G-patch PF01585.23 KXG52595.1 - 0.00082 19.2 0.1 0.0023 17.8 0.1 1.8 1 0 0 1 1 1 1 G-patch domain RTA1 PF04479.13 KXG52596.1 - 1.5e-59 201.1 6.5 1.5e-59 201.1 6.5 1.3 2 0 0 2 2 2 1 RTA1 like protein Colicin_V PF02674.16 KXG52596.1 - 1.5 8.8 9.5 0.82 9.6 1.5 3.3 1 1 3 4 4 4 0 Colicin V production protein Myb_DNA-bind_6 PF13921.6 KXG52597.1 - 2.4e-17 62.9 0.2 8.6e-17 61.1 0.2 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSA PF07529.13 KXG52597.1 - 1.7e-14 53.8 0.3 1.7e-14 53.8 0.3 4.1 4 0 0 4 4 4 1 HSA Myb_DNA-binding PF00249.31 KXG52597.1 - 0.00048 20.3 4.7 0.00063 19.9 0.3 3.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain WD40 PF00400.32 KXG52598.1 - 4.4e-10 40.0 0.0 0.24 12.4 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG52598.1 - 0.00015 22.0 0.3 30 5.0 0.0 4.8 5 0 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2_C PF09173.11 KXG52599.1 - 1.4e-34 118.2 0.4 3.4e-34 116.9 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KXG52599.1 - 9.8e-23 80.7 0.3 4.7e-22 78.5 0.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXG52599.1 - 1.9e-12 47.4 0.2 4.3e-12 46.2 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXG52599.1 - 0.01 15.9 0.0 0.023 14.8 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXG52599.1 - 0.015 15.2 0.1 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Peptidase_M48_N PF16491.5 KXG52600.1 - 8.7e-65 218.0 8.4 8.7e-65 218.0 8.4 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KXG52600.1 - 2.2e-45 154.8 0.0 3.8e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF4538 PF15061.6 KXG52600.1 - 0.075 12.8 1.1 0.21 11.3 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Peptidase_M56 PF05569.11 KXG52600.1 - 0.64 9.1 2.3 4.1 6.5 1.8 1.9 1 1 1 2 2 2 0 BlaR1 peptidase M56 RNA_polI_A14 PF08203.11 KXG52601.1 - 0.016 15.9 0.1 0.056 14.2 0.0 1.9 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 PcfK PF14058.6 KXG52601.1 - 0.051 13.9 4.2 0.48 10.7 4.0 2.0 2 0 0 2 2 2 0 PcfK-like protein Ribosomal_L34 PF00468.17 KXG52602.1 - 1.1e-12 47.7 11.9 1.1e-12 47.7 11.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L34 Peptidase_M16_C PF05193.21 KXG52603.1 - 7.1e-14 52.2 0.0 2.2e-10 40.9 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXG52603.1 - 2.7e-06 27.4 0.0 7.9e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Sigma70_ner PF04546.13 KXG52603.1 - 0.9 9.4 13.0 1.8 8.4 6.8 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Astro_capsid_p PF12226.8 KXG52603.1 - 1.2 8.2 10.2 1.9 7.5 10.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Sporozoite_P67 PF05642.11 KXG52603.1 - 5.3 5.0 7.5 7.9 4.4 7.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen WD40 PF00400.32 KXG52604.1 - 1.6e-20 73.0 13.7 1.7e-06 28.6 0.4 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.12 KXG52604.1 - 1.1e-19 70.6 0.6 4.3e-19 68.8 0.2 2.3 2 0 0 2 2 2 1 NLE (NUC135) domain Zw10 PF06248.13 KXG52604.1 - 1.2e-09 37.3 1.7 2.6e-09 36.2 0.2 2.1 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 Nup160 PF11715.8 KXG52604.1 - 0.00011 21.0 0.1 0.0034 16.1 0.1 2.7 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Dsl1_C PF11989.8 KXG52604.1 - 0.0031 17.3 0.0 0.0073 16.1 0.0 1.6 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal TMF_TATA_bd PF12325.8 KXG52604.1 - 0.25 11.6 3.0 0.31 11.3 1.0 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Ribosomal_S13 PF00416.22 KXG52605.1 - 4e-19 69.3 0.9 2.5e-14 53.7 2.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S13/S18 Ntox8 PF15545.6 KXG52605.1 - 0.013 15.6 0.2 0.018 15.1 0.2 1.3 1 0 0 1 1 1 0 Bacterial toxin 8 Pro_isomerase PF00160.21 KXG52606.1 - 7.3e-48 162.8 0.5 1e-47 162.3 0.5 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EphA2_TM PF14575.6 KXG52606.1 - 0.042 14.7 0.0 0.19 12.6 0.1 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FixS PF03597.15 KXG52606.1 - 0.095 12.4 2.5 1.1 9.0 0.2 2.3 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DEAD PF00270.29 KXG52607.1 - 1.3e-47 161.9 0.0 4.3e-47 160.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG52607.1 - 1.1e-32 112.7 0.0 2.9e-32 111.3 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG52607.1 - 0.0069 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KXG52607.1 - 0.048 13.0 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KXG52607.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 KXG52607.1 - 0.3 9.8 0.0 0.49 9.1 0.0 1.2 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 INSIG PF07281.12 KXG52609.1 - 2.6e-76 256.0 0.8 3.6e-76 255.5 0.8 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) DUF3040 PF11239.8 KXG52609.1 - 0.75 10.1 0.0 0.75 10.1 0.0 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF3040) AICARFT_IMPCHas PF01808.18 KXG52610.1 - 1.4e-89 300.4 0.0 2.3e-89 299.8 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KXG52610.1 - 7.1e-26 90.2 0.1 1.9e-25 88.8 0.0 1.8 2 0 0 2 2 2 1 MGS-like domain Pro-kuma_activ PF09286.11 KXG52611.1 - 3.2e-52 176.6 0.3 7.6e-52 175.4 0.1 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXG52611.1 - 0.038 13.2 0.0 0.17 11.2 0.0 1.8 1 1 0 1 1 1 0 Subtilase family Fumerase_C PF05683.12 KXG52611.1 - 0.084 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Fumarase C-terminus DUF3716 PF12511.8 KXG52612.1 - 2.4e-12 46.7 3.6 3.6e-12 46.1 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) CBM_X2 PF03442.14 KXG52612.1 - 0.1 12.7 0.2 0.35 11.0 0.0 1.9 2 0 0 2 2 2 0 Carbohydrate binding domain X2 Trypsin_2 PF13365.6 KXG52614.1 - 0.11 13.4 0.1 0.19 12.6 0.1 1.4 1 0 0 1 1 1 0 Trypsin-like peptidase domain MFS_1 PF07690.16 KXG52615.1 - 1.9e-27 96.1 27.2 1.9e-27 96.1 27.2 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF2244 PF10003.9 KXG52615.1 - 0.9 9.2 0.0 0.9 9.2 0.0 3.8 4 2 0 4 4 4 0 Integral membrane protein (DUF2244) Amidase PF01425.21 KXG52616.1 - 1.1e-93 314.7 0.0 1.3e-93 314.5 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF3927 PF13064.6 KXG52616.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3927) DUF3723 PF12520.8 KXG52619.1 - 8.9e-68 229.2 0.0 3.1e-64 217.5 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) PNP_UDP_1 PF01048.20 KXG52621.1 - 3.6e-13 49.3 0.2 2.1e-12 46.8 0.2 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.7 KXG52621.1 - 8.1e-13 48.8 0.4 4.9e-05 23.9 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) NACHT PF05729.12 KXG52621.1 - 7.4e-12 45.5 0.3 1.3e-11 44.7 0.3 1.4 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.6 KXG52621.1 - 2.6e-11 43.8 0.8 6.7e-05 23.4 0.1 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXG52621.1 - 3.8e-09 36.6 3.2 0.051 14.0 0.1 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXG52621.1 - 1e-08 35.3 0.4 0.001 19.3 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG52621.1 - 3.3e-05 23.9 0.8 15 6.5 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat AAA_16 PF13191.6 KXG52621.1 - 0.00011 22.7 0.4 0.00032 21.1 0.4 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXG52621.1 - 0.00015 22.0 0.2 0.00068 19.9 0.0 2.2 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KXG52621.1 - 0.054 12.7 0.0 0.2 10.8 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Cep57_MT_bd PF06657.13 KXG52622.1 - 0.03 14.7 0.1 4.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.12 KXG52622.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) RVT_1 PF00078.27 KXG52623.1 - 1.2e-25 90.3 0.0 2.8e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KXG52623.1 - 2.1e-23 82.4 1.0 5e-23 81.2 1.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KXG52623.1 - 0.00026 20.6 0.8 0.0007 19.2 0.8 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribonuclease_3 PF00636.26 KXG52624.1 - 2e-15 57.3 0.0 4.1e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXG52624.1 - 1.4e-12 47.8 0.0 2.9e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KXG52624.1 - 0.096 13.4 0.0 0.42 11.3 0.0 2.0 2 0 0 2 2 2 0 Double-stranded RNA binding motif DUF382 PF04037.13 KXG52625.1 - 7.5e-60 200.7 1.1 1.7e-59 199.5 1.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 KXG52625.1 - 4.9e-17 61.5 1.0 4.9e-17 61.5 1.0 2.3 3 0 0 3 3 3 1 PSP 40S_SA_C PF16122.5 KXG52625.1 - 2.6 9.5 10.8 3 9.3 0.1 3.1 3 0 0 3 3 3 0 40S ribosomal protein SA C-terminus ER_lumen_recept PF00810.18 KXG52627.1 - 2.1e-54 184.3 8.0 2.1e-54 184.3 8.0 1.6 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KXG52627.1 - 0.00082 19.1 14.4 0.35 10.7 0.3 4.0 3 1 1 4 4 4 3 PQ loop repeat XRCC4 PF06632.12 KXG52630.1 - 3.7e-08 32.6 15.1 2e-07 30.2 15.1 1.9 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 RunxI PF08504.11 KXG52630.1 - 3.8 8.3 5.8 0.43 11.3 0.6 2.1 2 0 0 2 2 2 0 Runx inhibition domain Molybdopterin PF00384.22 KXG52631.1 - 5.9e-71 239.7 0.0 3.3e-36 125.2 0.0 2.1 1 1 1 2 2 2 2 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.9 KXG52631.1 - 1.7e-17 62.6 0.2 1.7e-17 62.6 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.6 KXG52631.1 - 6.9e-07 29.2 0.3 3.8e-05 23.6 0.1 2.7 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 KXG52631.1 - 0.13 12.1 1.1 3.3 7.7 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 KXG52631.1 - 0.4 10.8 2.4 0.5 10.5 1.0 1.8 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.11 KXG52631.1 - 0.45 10.6 2.3 9.6 6.4 2.3 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster TPT PF03151.16 KXG52632.1 - 5.5e-60 203.2 15.0 6.8e-60 202.9 15.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXG52632.1 - 2.1e-07 31.2 32.8 0.00015 21.9 11.0 2.9 2 1 0 2 2 2 2 EamA-like transporter family PSII PF00421.19 KXG52632.1 - 0.0088 14.8 0.6 0.015 14.0 0.1 1.6 2 0 0 2 2 2 1 Photosystem II protein DUF5134 PF17197.4 KXG52632.1 - 2.5 8.0 5.0 29 4.5 0.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5134) PUF PF00806.19 KXG52633.1 - 1.5e-33 112.6 3.1 3.6e-05 23.2 0.0 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat DUF5572 PF17733.1 KXG52634.1 - 1.9e-23 82.0 0.2 3.6e-23 81.1 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Ssl1 PF04056.14 KXG52635.1 - 8.8e-48 162.7 0.0 1.7e-47 161.7 0.0 1.4 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 KXG52635.1 - 3.3e-05 24.5 0.0 0.00011 22.9 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain PsiE PF06146.12 KXG52635.1 - 0.033 14.6 0.0 0.066 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphate-starvation-inducible E ERAP1_C PF11838.8 KXG52636.1 - 3.5e-87 292.9 0.5 5.9e-87 292.2 0.5 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KXG52636.1 - 5.3e-83 277.9 3.2 1e-82 276.9 3.2 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Ras PF00071.22 KXG52636.1 - 4.6e-64 214.9 0.5 4.6e-64 214.9 0.5 1.9 2 0 0 2 2 2 1 Ras family Peptidase_M1_N PF17900.1 KXG52636.1 - 1.3e-42 146.1 0.4 1.7e-41 142.5 0.1 2.5 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Roc PF08477.13 KXG52636.1 - 1.1e-34 119.2 0.1 2.9e-34 117.8 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG52636.1 - 4.4e-15 55.6 0.1 1e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXG52636.1 - 0.00074 19.6 0.0 0.002 18.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXG52636.1 - 0.0026 17.7 0.4 1.2 9.1 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KXG52636.1 - 0.0031 17.1 0.1 0.0076 15.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXG52636.1 - 0.0035 16.7 0.1 0.0064 15.9 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KXG52636.1 - 0.016 14.7 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.29 KXG52636.1 - 0.027 14.9 0.1 4.6 7.7 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KXG52636.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KXG52636.1 - 0.16 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Mito_carr PF00153.27 KXG52637.1 - 6e-52 173.5 2.3 5.6e-17 61.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AphA_like PF14557.6 KXG52637.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator HMD PF03201.16 KXG52637.1 - 0.11 12.8 0.0 7.2 6.9 0.0 3.1 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase TadE PF07811.12 KXG52637.1 - 0.16 12.3 5.5 2.4 8.5 0.0 2.9 3 0 0 3 3 3 0 TadE-like protein Bacteriocin_IIc PF10439.9 KXG52637.1 - 0.19 11.9 2.2 6.3 7.0 0.2 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Nup160 PF11715.8 KXG52638.1 - 0.0093 14.7 0.6 0.022 13.4 0.1 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 WD40 PF00400.32 KXG52638.1 - 0.026 15.4 15.8 1.3 10.1 0.0 6.7 7 0 0 7 7 7 0 WD domain, G-beta repeat NPR3 PF03666.13 KXG52638.1 - 0.83 8.4 5.8 1.7 7.3 5.8 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 O_Spanin_T7 PF17531.2 KXG52638.1 - 1.3 9.1 5.1 0.47 10.5 1.9 2.0 2 0 0 2 2 2 0 outer-membrane spanin sub-unit WW PF00397.26 KXG52639.1 - 1.7e-11 44.0 2.1 4.4e-11 42.7 2.1 1.8 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 KXG52639.1 - 4.3e-05 23.7 29.9 4.3e-05 23.7 29.9 2.4 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF2012 PF09430.10 KXG52640.1 - 6.7e-30 103.7 0.0 8.5e-30 103.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) NCE101 PF11654.8 KXG52641.1 - 5.1e-09 35.7 0.1 1.1e-08 34.7 0.0 1.6 2 0 0 2 2 2 1 Non-classical export protein 1 HSP70 PF00012.20 KXG52642.1 - 6.5e-262 870.1 7.4 7.5e-262 869.9 7.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXG52642.1 - 2.3e-18 66.1 0.1 2.1e-17 62.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KXG52642.1 - 0.0013 18.5 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KXG52642.1 - 0.0054 17.1 4.4 4.7 7.7 0.0 3.6 3 2 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.20 KXG52642.1 - 0.018 14.5 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 KXG52642.1 - 0.029 13.6 0.1 0.06 12.6 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 KXG52642.1 - 0.045 13.0 0.0 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 StbA protein PMBR PF09373.10 KXG52642.1 - 0.074 13.2 0.1 0.44 10.8 0.1 2.3 2 0 0 2 2 2 0 Pseudomurein-binding repeat OPT PF03169.15 KXG52643.1 - 1.2e-136 456.9 45.9 1.3e-136 456.7 45.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.6 KXG52643.1 - 0.061 12.7 1.2 0.17 11.2 1.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) SieB PF14163.6 KXG52643.1 - 1.6 8.3 4.1 1.8 8.1 2.6 1.9 1 1 0 1 1 1 0 Super-infection exclusion protein B CHZ PF09649.10 KXG52644.1 - 5.9e-13 48.1 1.8 5.9e-13 48.1 1.8 2.3 2 1 0 2 2 2 1 Histone chaperone domain CHZ ANAPC15 PF15243.6 KXG52644.1 - 8.3 6.9 25.5 2.5 8.6 7.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Sipho_Gp157 PF05565.11 KXG52645.1 - 0.095 12.7 0.3 0.14 12.1 0.3 1.3 1 1 0 1 1 1 0 Siphovirus Gp157 Apc15p PF05841.11 KXG52646.1 - 4.9e-14 53.2 0.7 4.9e-14 53.2 0.7 2.1 2 1 0 2 2 2 1 Apc15p protein GATase_2 PF00310.21 KXG52647.1 - 7.1e-181 601.5 0.0 1.1e-180 600.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KXG52647.1 - 1.2e-154 514.9 0.0 1.7e-154 514.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KXG52647.1 - 9e-115 382.9 0.0 2.3e-112 375.0 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KXG52647.1 - 2.3e-86 288.3 1.8 3.7e-86 287.6 1.8 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KXG52647.1 - 3.5e-25 88.9 0.1 2.8e-24 85.9 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KXG52647.1 - 3.2e-21 75.2 0.1 6.5e-21 74.2 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 KXG52647.1 - 4.7e-08 33.5 0.1 0.00026 21.5 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG52647.1 - 7.8e-08 32.4 0.1 3.2e-07 30.5 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXG52647.1 - 3.7e-06 26.5 0.1 6.5e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KXG52647.1 - 1.8e-05 24.0 0.1 0.00041 19.5 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXG52647.1 - 2e-05 24.3 1.1 0.015 14.9 0.3 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXG52647.1 - 5.2e-05 22.6 4.8 0.038 13.2 0.0 3.9 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXG52647.1 - 6.6e-05 21.8 0.5 0.00016 20.6 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KXG52647.1 - 0.00023 20.7 0.1 0.00052 19.5 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXG52647.1 - 0.003 16.9 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KXG52647.1 - 0.0051 17.2 1.0 4.8 7.7 0.1 3.0 2 0 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KXG52647.1 - 0.013 14.8 0.1 2.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KXG52647.1 - 0.022 14.0 0.4 0.072 12.3 0.2 2.0 2 0 0 2 2 2 0 Thi4 family FMO-like PF00743.19 KXG52647.1 - 0.038 12.4 0.1 1.9 6.8 0.0 2.7 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.19 KXG52647.1 - 0.066 12.6 0.3 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMN_dh PF01070.18 KXG52647.1 - 0.094 11.7 3.6 0.083 11.9 0.9 2.2 3 0 0 3 3 3 0 FMN-dependent dehydrogenase IlvN PF07991.12 KXG52647.1 - 0.12 12.0 0.2 0.48 10.0 0.1 2.1 2 0 0 2 2 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KXG52647.1 - 0.16 12.6 0.1 3.3 8.4 0.1 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KXG52647.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MADF_DNA_bdg PF10545.9 KXG52647.1 - 0.16 12.3 0.4 0.4 11.0 0.4 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Lycopene_cycl PF05834.12 KXG52647.1 - 0.22 10.5 0.2 1 8.3 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 KXG52647.1 - 5.4 6.0 6.7 0.37 9.8 0.9 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Corona_nucleoca PF00937.18 KXG52648.1 - 0.41 9.6 5.3 0.16 10.9 3.2 1.3 1 1 0 1 1 1 0 Coronavirus nucleocapsid protein DUF3128 PF11326.8 KXG52649.1 - 7.1e-25 87.2 2.3 7.1e-25 87.2 2.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) RNA12 PF10443.9 KXG52650.1 - 1.9e-166 554.2 0.1 5.6e-166 552.7 0.1 1.8 1 1 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 KXG52650.1 - 7.4e-08 32.6 0.1 3.6e-07 30.4 0.1 2.0 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 KXG52650.1 - 3.2e-06 26.9 0.0 6.5e-05 22.7 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 KXG52650.1 - 0.00096 19.6 0.0 0.0028 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF2487 PF10673.9 KXG52650.1 - 0.0031 17.6 0.0 0.0081 16.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) ScsC_N PF18312.1 KXG52650.1 - 0.56 10.1 3.1 24 4.8 0.1 3.3 3 0 0 3 3 3 0 Copper resistance protein ScsC N-terminal domain p450 PF00067.22 KXG52651.1 - 2.6e-14 52.9 0.0 9.1e-12 44.5 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 ILVD_EDD PF00920.21 KXG52652.1 - 8.4e-159 529.5 0.2 1.3e-158 528.9 0.2 1.2 1 0 0 1 1 1 1 Dehydratase family Mcl1_mid PF12341.8 KXG52652.1 - 5e-102 341.2 0.0 2.9e-101 338.7 0.0 2.0 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 KXG52652.1 - 2.9e-14 53.1 0.0 2.8e-05 24.3 0.0 6.5 3 1 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXG52652.1 - 5.9e-14 52.2 0.9 2.9e-05 24.7 0.0 7.0 8 0 0 8 8 8 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KXG52652.1 - 6.5e-06 25.5 0.0 2.9e-05 23.3 0.0 1.8 1 1 1 2 2 2 1 Coatomer WD associated region Cytochrom_D1 PF02239.16 KXG52652.1 - 0.063 11.8 0.3 1.1 7.7 0.1 2.3 1 1 1 2 2 2 0 Cytochrome D1 heme domain DNA_pol_alpha_N PF12254.8 KXG52652.1 - 0.068 13.3 3.7 0.15 12.2 3.7 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Collagen_bind_2 PF12904.7 KXG52652.1 - 0.11 12.5 0.1 0.37 10.8 0.1 1.9 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase MMU163 PF17119.5 KXG52653.1 - 2.3e-115 384.0 0.1 2.9e-115 383.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis MFS_1 PF07690.16 KXG52654.1 - 7.1e-44 150.2 29.5 4.1e-42 144.4 15.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG52654.1 - 4.9e-07 29.0 1.3 4.9e-07 29.0 1.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KXG52654.1 - 8.4e-05 21.2 0.5 0.00013 20.6 0.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KXG52654.1 - 0.11 11.3 5.4 2.9 6.7 5.4 2.4 1 1 0 1 1 1 0 MFS_1 like family V_ATPase_I PF01496.19 KXG52655.1 - 4.7 5.0 6.8 6.1 4.6 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NUDIX PF00293.28 KXG52656.1 - 1.3e-11 44.6 0.0 2.6e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain CBFD_NFYB_HMF PF00808.23 KXG52656.1 - 0.001 19.3 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 KXG52656.1 - 0.0011 19.2 0.1 0.0017 18.5 0.1 1.4 1 0 0 1 1 1 1 CENP-W protein VTC PF09359.10 KXG52657.1 - 6.1e-87 291.5 0.5 9.2e-87 290.9 0.0 1.5 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 KXG52657.1 - 2.9e-13 50.0 2.7 2.9e-13 50.0 2.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KXG52657.1 - 3.8e-07 30.4 17.3 0.00016 21.7 0.1 4.1 2 2 1 4 4 4 3 SPX domain KxDL PF10241.9 KXG52657.1 - 5.2 7.4 5.4 3.1 8.1 2.1 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein DSBA PF01323.20 KXG52658.1 - 8.9e-31 107.2 0.1 3.8e-30 105.1 0.1 1.7 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 KXG52658.1 - 0.06 13.4 0.1 1.8 8.6 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin domain 6PF2K PF01591.18 KXG52659.1 - 5.6e-71 238.4 0.0 1.4e-50 171.7 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXG52659.1 - 1.1e-33 116.6 0.1 1.2e-25 90.3 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KXG52659.1 - 2.2e-05 24.7 0.0 0.2 11.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain KTI12 PF08433.10 KXG52659.1 - 0.071 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF5128 PF17170.4 KXG52659.1 - 0.072 12.2 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 6-bladed beta-propeller DUF202 PF02656.15 KXG52660.1 - 0.0026 18.2 9.0 0.026 15.0 9.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF202) FMN_dh PF01070.18 KXG52661.1 - 3e-107 358.7 0.0 3.6e-107 358.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXG52661.1 - 4.6e-20 71.5 0.0 1e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KXG52661.1 - 3.2e-06 26.4 0.5 0.00014 21.0 0.0 2.8 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXG52661.1 - 5.4e-06 25.8 0.0 1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KXG52661.1 - 0.025 14.1 0.0 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein NMO PF03060.15 KXG52661.1 - 0.063 12.7 0.3 0.11 11.9 0.3 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase ATP11 PF06644.11 KXG52661.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein NMO PF03060.15 KXG52662.1 - 1.1e-32 113.7 3.8 1.2e-28 100.5 1.6 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KXG52662.1 - 2.9e-09 36.4 0.0 8.4e-08 31.6 0.0 2.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXG52662.1 - 6e-08 32.1 2.0 8.8e-08 31.5 2.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXG52662.1 - 0.011 14.9 0.9 0.019 14.1 0.9 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase Cauli_VI PF01693.16 KXG52663.1 - 5e-37 125.9 6.0 1.5e-18 66.8 1.2 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 KXG52663.1 - 1e-34 119.8 0.0 1.6e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KXG52663.1 - 0.089 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like Na_H_Exchanger PF00999.21 KXG52664.1 - 1.5e-47 162.2 18.9 1.9e-47 161.9 18.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3112 PF11309.8 KXG52664.1 - 0.14 11.6 0.5 0.26 10.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Chorismate_bind PF00425.18 KXG52665.1 - 1.3e-21 77.3 0.0 1.4e-21 77.2 0.0 1.0 1 0 0 1 1 1 1 chorismate binding enzyme Ge1_WD40 PF16529.5 KXG52666.1 - 0.0009 18.3 0.0 0.0025 16.8 0.0 1.7 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF445 PF04286.12 KXG52666.1 - 0.2 11.4 9.6 0.083 12.7 4.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Chs7 PF12271.8 KXG52667.1 - 5.2e-100 334.5 3.6 6.3e-100 334.2 3.6 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3112 PF11309.8 KXG52667.1 - 0.11 12.0 0.4 0.43 10.0 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) TssN PF17555.2 KXG52667.1 - 1.5 8.1 13.4 1.9 7.8 4.5 2.3 1 1 1 2 2 2 0 Type VI secretion system, TssN DLH PF01738.18 KXG52668.1 - 2.9e-29 102.2 0.0 3.6e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KXG52668.1 - 0.008 16.1 0.0 0.3 11.0 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal LIDHydrolase PF10230.9 KXG52668.1 - 0.025 14.1 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_S15 PF02129.18 KXG52668.1 - 0.031 13.9 0.0 0.067 12.8 0.0 1.4 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 KXG52668.1 - 0.094 12.4 0.0 0.25 11.0 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) ERG4_ERG24 PF01222.17 KXG52669.1 - 3.3e-141 470.9 21.6 3.9e-141 470.7 21.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family zf-C3HC4 PF00097.25 KXG52670.1 - 3.2e-07 30.1 7.7 5.4e-07 29.4 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXG52670.1 - 2.6e-06 27.4 3.0 2.6e-06 27.4 3.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXG52670.1 - 2.7e-06 27.1 4.8 2.4e-05 24.1 2.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXG52670.1 - 7.2e-06 26.2 8.0 7.2e-05 23.0 8.5 2.1 1 1 1 2 2 2 2 Ring finger domain zf-C3HC4_4 PF15227.6 KXG52670.1 - 1.7e-05 24.9 4.9 0.00012 22.2 5.5 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KXG52670.1 - 2.2e-05 24.3 4.8 5.2e-05 23.1 4.8 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXG52670.1 - 2.7e-05 23.9 6.9 6.1e-05 22.8 6.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXG52670.1 - 0.052 13.4 9.2 0.47 10.4 9.3 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KXG52670.1 - 0.29 11.3 2.1 0.67 10.1 2.1 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KXG52670.1 - 1.8 8.4 6.6 8.5 6.2 3.8 2.7 2 1 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.7 KXG52670.1 - 8.3 6.8 7.5 27 5.2 7.5 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain UCH PF00443.29 KXG52671.1 - 1.1e-46 159.5 0.0 1.6e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXG52671.1 - 1.1e-10 41.6 0.0 2.9e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ndc1_Nup PF09531.10 KXG52671.1 - 0.47 9.1 5.1 0.7 8.5 5.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup dCMP_cyt_deam_1 PF00383.23 KXG52672.1 - 5.2e-05 23.1 0.2 0.38 10.6 0.1 2.4 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Cyclin PF08613.11 KXG52673.1 - 1.3e-32 113.4 0.7 3.4e-32 112.1 0.7 1.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXG52673.1 - 0.00017 21.3 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DEC-1_N PF04625.13 KXG52673.1 - 0.008 15.2 4.9 0.014 14.5 4.9 1.3 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region Arm PF00514.23 KXG52674.1 - 4.1e-17 61.6 3.7 7.8e-05 22.6 0.2 8.3 10 0 0 10 10 10 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KXG52674.1 - 0.0027 18.2 1.8 4.2 8.0 0.0 6.0 6 0 0 6 6 6 1 HEAT-like repeat IFRD PF05004.13 KXG52674.1 - 0.076 12.1 0.1 0.19 10.8 0.1 1.6 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 KXG52674.1 - 0.077 13.3 8.7 31 5.2 0.1 7.1 9 1 1 10 10 10 0 HEAT repeat Fructosamin_kin PF03881.14 KXG52675.1 - 3.6e-68 229.9 0.0 5.6e-68 229.2 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase Cyclin_N PF00134.23 KXG52675.1 - 4.3e-10 39.4 0.0 5.5e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain APH PF01636.23 KXG52675.1 - 3.4e-06 27.2 0.0 7.7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family CTP_transf_1 PF01148.20 KXG52676.1 - 4.3e-81 272.6 21.0 5.3e-81 272.3 21.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.8 KXG52677.1 - 2.7e-48 163.6 0.3 4.9e-48 162.7 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 KXG52677.1 - 3.4e-06 25.9 1.3 0.6 8.6 0.1 3.1 2 1 1 3 3 3 3 DNA damage checkpoint protein Flg_hook PF02120.16 KXG52677.1 - 0.033 14.1 0.2 0.099 12.5 0.2 1.8 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK DUF4461 PF14688.6 KXG52677.1 - 0.19 11.5 3.1 0.16 11.8 1.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4461) Lebercilin PF15619.6 KXG52677.1 - 0.45 10.1 10.3 0.16 11.6 7.1 1.8 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Golgin_A5 PF09787.9 KXG52677.1 - 0.64 9.4 10.1 1.2 8.5 10.1 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Mu-like_Pro PF10123.9 KXG52677.1 - 0.67 9.4 10.1 0.26 10.8 7.0 1.7 1 1 0 2 2 2 0 Mu-like prophage I protein Phage_Mu_Gam PF07352.12 KXG52677.1 - 1.5 8.7 5.7 0.67 9.8 3.1 1.7 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein YabA PF06156.13 KXG52677.1 - 9.5 6.9 7.3 5.3 7.7 1.0 2.6 1 1 1 2 2 2 0 Initiation control protein YabA S4 PF01479.25 KXG52678.1 - 8.6e-16 57.4 0.0 1.8e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 S4 domain Glyco_hydro_11 PF00457.17 KXG52678.1 - 0.11 12.1 0.5 0.2 11.3 0.5 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 S4_2 PF13275.6 KXG52678.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 S4 domain HSP70 PF00012.20 KXG52678.1 - 1.8 6.6 8.1 0.19 9.9 3.6 1.5 1 1 1 2 2 2 0 Hsp70 protein FUSC PF04632.12 KXG52678.1 - 3.6 6.0 6.5 2.2 6.7 4.4 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family SPG4 PF17325.2 KXG52678.1 - 4.9 8.3 5.7 2.3 9.4 0.8 2.4 2 0 0 2 2 2 0 Stationary phase protein 4 NpwBP PF12622.7 KXG52679.1 - 0.0067 17.2 0.2 0.024 15.4 0.2 2.0 1 0 0 1 1 1 1 mRNA biogenesis factor DUF382 PF04037.13 KXG52679.1 - 0.043 14.0 0.2 0.089 13.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF382) E1_dh PF00676.20 KXG52680.1 - 3.6e-114 380.8 0.3 4.2e-114 380.5 0.3 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KXG52680.1 - 0.0012 18.2 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DNA_pol_B PF00136.21 KXG52685.1 - 4.3e-150 500.4 1.1 6.1e-150 499.9 1.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KXG52685.1 - 3e-78 263.3 0.0 5.1e-78 262.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KXG52685.1 - 3.9e-18 65.7 7.1 8.3e-18 64.6 7.1 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KXG52685.1 - 0.0015 17.5 0.2 0.012 14.5 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 KXG52685.1 - 0.013 15.5 0.5 0.094 12.7 0.5 2.4 1 1 0 1 1 1 0 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 KXG52685.1 - 0.058 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB ETC_C1_NDUFA5 PF04716.14 KXG52685.1 - 0.074 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 ETC complex I subunit conserved region Pkinase PF00069.25 KXG52686.1 - 5.1e-34 117.8 0.0 6.2e-19 68.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG52686.1 - 3.9e-17 62.4 0.0 8.2e-07 28.6 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase FTA2 PF13095.6 KXG52686.1 - 0.08 12.6 0.0 10 5.7 0.0 2.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KXG52686.1 - 0.12 11.7 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXG52686.1 - 0.12 11.1 0.0 0.12 11.1 0.0 2.2 3 0 0 3 3 3 0 Fungal protein kinase Acyl-CoA_dh_1 PF00441.24 KXG52687.1 - 1.2e-29 103.5 0.2 1.7e-29 102.9 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXG52687.1 - 2.2e-26 92.7 0.0 6e-26 91.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXG52687.1 - 3.4e-24 84.9 0.1 5.5e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXG52687.1 - 0.0017 18.6 0.1 0.003 17.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glyco_hydro_125 PF06824.11 KXG52688.1 - 1.8e-178 593.7 0.0 2.4e-178 593.3 0.0 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) CDC27 PF09507.10 KXG52688.1 - 2.3e-92 310.6 22.0 2.9e-92 310.3 22.0 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 zf-C3HC4_2 PF13923.6 KXG52689.1 - 2.1e-11 43.4 15.7 9.2e-11 41.4 11.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXG52689.1 - 3.2e-08 33.3 16.2 1.8e-07 30.9 12.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXG52689.1 - 4.1e-08 32.9 12.6 1.8e-07 30.9 9.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXG52689.1 - 8.5e-08 32.1 14.6 9.2e-07 28.8 10.7 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXG52689.1 - 2.5e-07 30.5 16.7 8.4e-07 28.9 12.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 KXG52689.1 - 3.2e-06 26.9 5.4 3.2e-06 26.9 5.4 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 KXG52689.1 - 4.8e-06 26.8 15.3 6.2e-05 23.3 12.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KXG52689.1 - 4.2e-05 23.6 12.5 4.2e-05 23.6 12.5 2.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING SAP PF02037.27 KXG52689.1 - 5.2e-05 22.9 0.7 0.00015 21.4 0.0 2.1 2 0 0 2 2 2 1 SAP domain Mob_synth_C PF06463.13 KXG52689.1 - 0.00014 21.8 1.7 0.00041 20.3 1.7 1.8 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Prok-RING_4 PF14447.6 KXG52689.1 - 0.00037 20.3 13.6 0.051 13.5 11.4 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KXG52689.1 - 0.0022 18.1 6.2 0.005 17.0 6.2 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KXG52689.1 - 0.0027 17.9 7.2 0.0027 17.9 7.2 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain U-box PF04564.15 KXG52689.1 - 0.0087 16.2 0.0 0.036 14.2 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-RING_4 PF14570.6 KXG52689.1 - 0.04 13.7 12.7 0.15 11.8 10.0 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KXG52689.1 - 0.043 13.9 2.8 0.11 12.6 2.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Snf7 PF03357.21 KXG52690.1 - 6.7e-16 58.4 11.9 7.2e-16 58.3 10.8 1.5 1 1 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 KXG52690.1 - 0.12 12.9 2.7 12 6.5 2.7 2.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TssO PF17561.2 KXG52690.1 - 0.28 11.3 1.6 0.4 10.8 0.3 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssO Tti2 PF10521.9 KXG52691.1 - 1.4e-92 310.2 1.0 2.8e-92 309.3 0.7 1.7 2 0 0 2 2 2 1 Tti2 family PolyA_pol PF01743.20 KXG52691.1 - 2.4e-21 76.5 1.5 1.9e-20 73.6 1.5 2.4 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KXG52691.1 - 1.3e-08 34.4 0.1 4.1e-08 32.9 0.1 1.9 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KXG52691.1 - 0.0012 18.9 0.1 0.0042 17.1 0.0 2.0 2 0 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative Syja_N PF02383.18 KXG52692.1 - 6e-82 275.5 0.0 9.8e-82 274.8 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Catalase PF00199.19 KXG52693.1 - 6.2e-157 522.6 5.0 2.1e-122 408.9 1.0 2.1 1 1 1 2 2 2 2 Catalase Pex2_Pex12 PF04757.14 KXG52693.1 - 3.2e-55 187.2 2.3 4.6e-55 186.7 2.3 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Catalase-rel PF06628.12 KXG52693.1 - 5.8e-08 32.8 0.0 1.3e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive zf-C3HC4_4 PF15227.6 KXG52693.1 - 6.9e-05 22.9 2.3 0.00014 21.9 2.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KXG52693.1 - 0.0011 18.8 2.4 0.002 18.0 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXG52693.1 - 0.01 15.6 1.9 0.017 15.0 1.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXG52693.1 - 0.014 15.8 2.4 0.027 14.8 2.4 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KXG52693.1 - 0.045 13.6 1.6 0.08 12.8 1.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXG52693.1 - 0.047 13.7 2.6 0.093 12.8 2.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DUF4456 PF14644.6 KXG52693.1 - 0.14 11.8 0.4 0.23 11.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) RsfS PF02410.15 KXG52694.1 - 4.5e-12 46.3 0.0 9e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation NMD3 PF04981.13 KXG52695.1 - 1.5e-77 260.4 5.9 1.5e-77 260.4 5.9 1.7 2 0 0 2 2 2 1 NMD3 family zf_Rg PF17915.1 KXG52695.1 - 0.11 11.9 1.5 0.39 10.2 0.2 2.2 2 0 0 2 2 2 0 Reverse gyrase zinc finger WRNPLPNID PF15017.6 KXG52695.1 - 0.11 13.4 0.0 0.11 13.4 0.0 3.2 2 1 0 2 2 2 0 Putative WW-binding domain and destruction box HypA PF01155.19 KXG52695.1 - 7.1 6.7 11.2 8.3 6.5 0.8 3.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ATP-grasp_4 PF13535.6 KXG52696.1 - 4.8e-14 52.3 0.0 3.1e-13 49.6 0.0 2.3 2 1 0 2 2 2 1 ATP-grasp domain ATPgrasp_N PF18130.1 KXG52696.1 - 2.2e-10 41.0 0.1 4.9e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp N-terminal domain Dala_Dala_lig_C PF07478.13 KXG52696.1 - 1.6e-07 31.1 0.0 2.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 KXG52696.1 - 2.3e-05 24.0 0.0 0.00015 21.3 0.0 2.2 3 0 0 3 3 3 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 KXG52696.1 - 0.0002 21.4 0.0 0.0042 17.2 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KXG52696.1 - 0.0083 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KXG52696.1 - 0.042 13.4 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 KXG52696.1 - 0.11 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain DUF150_C PF17384.2 KXG52696.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Ribosomal_L12 PF00542.19 KXG52697.1 - 0.02 15.2 1.7 0.059 13.7 1.7 1.8 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain Mito_carr PF00153.27 KXG52698.1 - 1.5e-62 207.5 2.4 1.4e-22 79.4 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXG52698.1 - 0.017 14.3 0.0 6.9 5.7 0.0 2.5 2 0 0 2 2 2 0 Gammaproteobacterial serine protease WAC_Acf1_DNA_bd PF10537.9 KXG52699.1 - 2.5e-40 137.1 0.2 2.5e-40 137.1 0.2 2.9 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KXG52699.1 - 7.1e-23 81.0 0.5 7.1e-23 81.0 0.5 3.4 4 0 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KXG52699.1 - 4.3e-17 62.2 2.3 9.5e-17 61.1 2.3 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KXG52699.1 - 9.6e-07 28.2 0.1 2.2e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 V_ATPase_I PF01496.19 KXG52699.1 - 3.6 5.4 5.3 4 5.2 0.8 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Alg6_Alg8 PF03155.15 KXG52700.1 - 2.6e-173 577.4 29.4 3e-173 577.2 29.4 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF4191 PF13829.6 KXG52700.1 - 0.18 11.1 0.2 0.46 9.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Lectin_leg-like PF03388.13 KXG52701.1 - 6.2e-30 104.2 0.0 8.6e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family BBP1_C PF15272.6 KXG52701.1 - 0.054 13.3 1.8 0.083 12.7 1.8 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Stevor PF17410.2 KXG52701.1 - 0.098 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF5385 PF17359.2 KXG52701.1 - 0.69 9.4 4.0 0.19 11.3 0.8 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Nup54 PF13874.6 KXG52701.1 - 2.6 8.1 6.6 4 7.5 6.6 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 PHD PF00628.29 KXG52702.1 - 9.4e-17 60.7 25.2 2.6e-10 40.0 10.5 2.5 2 0 0 2 2 2 2 PHD-finger zf-RanBP PF00641.18 KXG52702.1 - 0.017 14.5 0.2 0.017 14.5 0.2 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others C1_1 PF00130.22 KXG52702.1 - 0.19 11.7 16.0 0.11 12.4 3.6 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 KXG52702.1 - 1.4 8.5 16.1 0.33 10.5 0.6 3.4 3 0 0 3 3 3 0 PHD-finger Peptidase_M24 PF00557.24 KXG52703.1 - 5.6e-07 29.4 0.0 8.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Exo_endo_phos PF03372.23 KXG52704.1 - 4.1e-09 36.3 0.0 1.2e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF5 PF04855.12 KXG52705.1 - 6e-64 216.1 0.5 6.3e-63 212.7 0.5 2.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 HEAT_2 PF13646.6 KXG52706.1 - 5.8e-08 33.0 1.8 0.0018 18.6 0.0 4.3 4 0 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 KXG52706.1 - 4.2e-05 23.6 1.0 0.7 9.9 0.0 4.5 5 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXG52706.1 - 5.5e-05 23.1 6.6 0.075 13.3 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 KXG52706.1 - 0.0095 16.4 2.9 0.51 10.9 0.1 4.5 4 0 0 4 4 4 1 HEAT-like repeat Nipped-B_C PF12830.7 KXG52706.1 - 0.022 14.7 0.5 0.37 10.7 0.1 2.8 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus Adaptin_N PF01602.20 KXG52706.1 - 0.2 10.1 1.8 1.6 7.2 0.0 3.1 4 1 0 4 4 4 0 Adaptin N terminal region XPC-binding PF09280.11 KXG52706.1 - 0.4 10.5 3.2 3.8 7.3 0.6 2.7 2 0 0 2 2 2 0 XPC-binding domain MFS_1 PF07690.16 KXG52707.1 - 3.3e-41 141.4 39.3 3.3e-41 141.4 39.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_Dp1 PF16938.5 KXG52707.1 - 0.94 9.7 8.6 2.2 8.6 0.4 3.9 3 0 0 3 3 3 0 Putative phage holin Dp-1 AAA PF00004.29 KXG52708.1 - 2.7e-97 322.3 0.0 4e-47 159.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXG52708.1 - 2.9e-22 78.2 6.0 2.1e-12 46.6 1.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KXG52708.1 - 5.6e-19 68.1 1.0 1.6e-18 66.7 0.5 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KXG52708.1 - 2.7e-14 53.2 0.0 1.2e-05 25.1 0.0 3.6 4 1 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXG52708.1 - 4.5e-14 52.9 0.0 1.5e-07 31.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KXG52708.1 - 1e-12 48.4 0.0 1.5e-05 25.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXG52708.1 - 2.2e-12 47.7 0.0 0.00021 21.7 0.0 4.6 3 2 1 4 4 3 2 AAA ATPase domain AAA_5 PF07728.14 KXG52708.1 - 2.1e-11 44.0 0.5 2e-05 24.6 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 KXG52708.1 - 1.9e-09 37.1 0.0 4.1e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 KXG52708.1 - 3.1e-09 37.2 0.4 0.032 14.5 0.0 4.3 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 KXG52708.1 - 3.8e-09 36.2 0.1 0.0015 17.8 0.0 2.6 2 1 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 KXG52708.1 - 1.4e-07 31.1 0.6 0.011 15.2 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXG52708.1 - 5.6e-07 29.5 0.0 0.019 14.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Vps4_C PF09336.10 KXG52708.1 - 5.7e-07 29.4 0.1 1.7e-05 24.7 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 KXG52708.1 - 6.1e-07 29.8 0.0 0.029 14.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 KXG52708.1 - 6.7e-07 29.4 0.0 0.015 15.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXG52708.1 - 7.1e-07 29.8 0.0 0.029 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KXG52708.1 - 3.2e-06 26.7 0.4 0.52 9.6 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 KXG52708.1 - 5.7e-06 26.0 0.1 0.042 13.3 0.0 3.1 2 2 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 KXG52708.1 - 6.8e-06 25.8 3.8 0.35 10.4 0.1 4.6 3 2 1 5 5 5 1 AAA domain AAA_24 PF13479.6 KXG52708.1 - 9.3e-06 25.5 0.0 0.13 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 KXG52708.1 - 1.5e-05 24.2 0.1 0.052 12.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 KXG52708.1 - 2.2e-05 23.8 0.0 0.015 14.5 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 KXG52708.1 - 2.6e-05 24.5 0.0 0.18 12.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 KXG52708.1 - 4.3e-05 23.3 0.1 0.46 10.2 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.18 KXG52708.1 - 6e-05 23.0 0.0 0.41 10.5 0.0 3.2 4 0 0 4 4 4 2 Bacterial dnaA protein AAA_17 PF13207.6 KXG52708.1 - 0.00014 22.3 0.3 0.59 10.6 0.0 3.4 4 0 0 4 4 2 1 AAA domain TsaE PF02367.17 KXG52708.1 - 0.00015 21.7 0.0 0.33 10.9 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KXG52708.1 - 0.00022 21.8 0.0 0.56 10.7 0.0 3.4 2 1 0 2 2 2 1 ABC transporter ResIII PF04851.15 KXG52708.1 - 0.00024 21.2 0.0 0.075 13.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KXG52708.1 - 0.00028 20.4 0.4 0.7 9.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.12 KXG52708.1 - 0.00028 20.8 0.1 0.18 11.7 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.11 KXG52708.1 - 0.0004 20.3 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KXG52708.1 - 0.00041 20.2 0.1 1.1 9.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXG52708.1 - 0.00048 19.9 0.2 0.56 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KXG52708.1 - 0.00067 19.6 0.0 4.4 7.1 0.0 3.6 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KXG52708.1 - 0.0019 17.5 0.0 1.5 8.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KXG52708.1 - 0.0042 16.8 0.0 0.35 10.6 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KXG52708.1 - 0.0052 17.1 0.7 5.7 7.3 0.0 3.4 3 1 0 4 4 2 0 AAA domain Zeta_toxin PF06414.12 KXG52708.1 - 0.0075 15.6 0.3 6 6.1 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin NTPase_1 PF03266.15 KXG52708.1 - 0.0084 16.0 0.6 2.5 8.0 0.0 4.1 4 0 0 4 4 3 1 NTPase NB-ARC PF00931.22 KXG52708.1 - 0.0086 15.3 0.0 1.7 7.7 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain KAP_NTPase PF07693.14 KXG52708.1 - 0.015 14.6 0.3 1.2 8.3 0.0 3.0 2 2 0 4 4 4 0 KAP family P-loop domain IPT PF01745.16 KXG52708.1 - 0.017 14.6 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Sigma54_activ_2 PF14532.6 KXG52708.1 - 0.029 14.5 0.0 4.1 7.5 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain UFD1 PF03152.14 KXG52708.1 - 0.047 13.2 0.0 0.37 10.2 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Cytidylate_kin PF02224.18 KXG52708.1 - 0.054 13.2 0.0 10 5.8 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase Zot PF05707.12 KXG52708.1 - 0.054 13.1 0.0 2.5 7.7 0.0 3.0 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_6 PF12774.7 KXG52708.1 - 0.064 12.2 0.0 9.1 5.1 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AFG1_ATPase PF03969.16 KXG52708.1 - 0.066 12.1 0.0 8.7 5.1 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase Cytidylate_kin2 PF13189.6 KXG52708.1 - 0.066 13.3 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family PEX11 PF05648.14 KXG52709.1 - 8e-12 45.1 0.1 5e-10 39.2 0.1 2.0 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) FUSC PF04632.12 KXG52710.1 - 0.19 10.2 3.0 0.31 9.5 3.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Mpv17_PMP22 PF04117.12 KXG52711.1 - 6.3e-13 48.7 1.4 1.5e-11 44.4 1.0 2.4 2 0 0 2 2 2 1 Mpv17 / PMP22 family Cullin_binding PF03556.15 KXG52712.1 - 1.4e-32 112.7 2.8 2.6e-32 111.8 2.8 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 KXG52712.1 - 3e-08 33.3 0.0 5.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UPF0113_N PF17833.1 KXG52713.1 - 5.4e-25 87.8 0.0 7.6e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KXG52713.1 - 3.2e-22 78.6 0.0 4.9e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 KXG52713.1 - 5e-06 26.4 0.0 7.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 PUA domain NOC3p PF07540.11 KXG52714.1 - 4.8e-32 110.3 0.2 2.2e-31 108.2 0.2 2.2 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 KXG52714.1 - 6e-26 91.5 0.1 6e-26 91.5 0.1 2.4 3 0 0 3 3 3 1 CBF/Mak21 family SLX9 PF15341.6 KXG52714.1 - 1.6 9.1 11.5 0.083 13.3 3.3 2.6 3 0 0 3 3 3 0 Ribosome biogenesis protein SLX9 V-SNARE PF05008.15 KXG52715.1 - 0.0096 16.3 0.2 0.034 14.5 0.2 1.9 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus TFIIA PF03153.13 KXG52715.1 - 2.6 7.9 13.1 0.35 10.8 5.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2203 PF09969.9 KXG52715.1 - 3.8 8.3 6.0 0.4 11.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) ANAPC9 PF12856.7 KXG52716.1 - 0.016 15.4 4.9 0.15 12.3 4.9 2.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 SLAC1 PF03595.17 KXG52717.1 - 8.3e-98 327.6 52.3 9.4e-98 327.4 52.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel m04gp34like PF12216.8 KXG52717.1 - 0.11 12.1 0.2 3.4 7.2 0.1 2.2 2 0 0 2 2 2 0 Immune evasion protein DUF5056 PF16479.5 KXG52717.1 - 0.4 11.0 2.7 1.1 9.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) Isochorismatase PF00857.20 KXG52718.1 - 1.1e-42 146.2 0.1 1.2e-42 146.1 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family ATP-synt_C PF00137.21 KXG52720.1 - 6.8e-09 35.9 13.6 1.3e-08 35.1 13.6 1.5 1 0 0 1 1 1 1 ATP synthase subunit C FIN1 PF17300.2 KXG52720.1 - 0.018 14.5 0.1 0.021 14.3 0.1 1.1 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 DUF1349 PF07081.11 KXG52721.1 - 2.6e-22 79.4 0.0 3.3e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Cript PF10235.9 KXG52722.1 - 6.1e-22 78.0 11.0 6.1e-22 78.0 11.0 2.1 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT Antimicrobial18 PF08130.11 KXG52722.1 - 0.025 14.7 0.2 0.053 13.6 0.2 1.6 1 0 0 1 1 1 0 Type A lantibiotic family DZR PF12773.7 KXG52722.1 - 0.064 13.3 13.6 0.14 12.2 8.4 2.8 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KXG52722.1 - 0.22 12.3 10.2 0.24 12.2 6.9 2.7 2 1 0 2 2 2 0 zinc-ribbon family DUF4730 PF15873.5 KXG52722.1 - 0.33 11.2 0.1 0.33 11.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4730) MRP-L46 PF11788.8 KXG52723.1 - 1.4e-38 132.3 1.3 2.6e-38 131.4 1.3 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KXG52723.1 - 0.00041 20.4 0.0 0.00084 19.4 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain CAF1 PF04857.20 KXG52724.1 - 1.2e-76 257.9 0.0 1.4e-76 257.7 0.0 1.0 1 0 0 1 1 1 1 CAF1 family ribonuclease ATP1G1_PLM_MAT8 PF02038.16 KXG52725.1 - 0.19 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family SBF_like PF13593.6 KXG52726.1 - 5.6e-64 216.4 13.2 9e-50 169.8 8.3 2.0 1 1 1 2 2 2 2 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KXG52726.1 - 0.00017 21.3 3.5 0.00031 20.5 3.5 1.4 1 0 0 1 1 1 1 Sodium Bile acid symporter family Mem_trans PF03547.18 KXG52726.1 - 0.082 11.3 5.8 0.19 10.1 0.0 2.4 2 1 1 3 3 3 0 Membrane transport protein DUF2721 PF11026.8 KXG52726.1 - 0.19 11.6 3.1 0.21 11.5 1.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) Mito_carr PF00153.27 KXG52728.1 - 6.8e-65 215.0 3.6 3.3e-22 78.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 KXG52728.1 - 9.8 6.3 8.2 3.2 7.9 0.3 3.5 4 0 0 4 4 4 0 Pre-toxin domain with VENN motif Cofilin_ADF PF00241.20 KXG52729.1 - 3.1e-24 85.1 0.0 3e-13 49.6 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Pinin_SDK_memA PF04696.13 KXG52730.1 - 8.8e-31 106.7 9.2 8.8e-31 106.7 9.2 2.4 3 0 0 3 3 3 1 pinin/SDK/memA/ protein conserved region RSB_motif PF16294.5 KXG52730.1 - 0.0031 17.8 5.7 0.0031 17.8 5.7 3.8 3 1 0 4 4 4 1 RNSP1-SAP18 binding (RSB) motif Abhydrolase_1 PF00561.20 KXG52731.1 - 8e-17 61.7 0.1 9.5e-08 32.0 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG52731.1 - 1.6e-11 45.3 1.6 4.6e-11 43.8 1.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG52731.1 - 1.4e-06 27.8 0.0 0.0017 17.7 0.0 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KXG52731.1 - 0.0047 17.0 0.0 0.0086 16.2 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Sacchrp_dh_NADP PF03435.18 KXG52732.1 - 2.9e-17 63.2 0.0 4.1e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ribosomal_L37ae PF01780.19 KXG52733.1 - 1.1e-40 137.5 9.8 1.3e-40 137.4 9.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KXG52733.1 - 0.0021 18.2 1.8 0.0029 17.7 1.8 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF1451 PF07295.11 KXG52733.1 - 0.0049 16.9 0.8 0.0067 16.5 0.8 1.2 1 0 0 1 1 1 1 Zinc-ribbon containing domain A2L_zn_ribbon PF08792.10 KXG52733.1 - 0.011 15.4 2.1 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KXG52733.1 - 0.014 15.3 1.9 0.024 14.6 1.9 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Rep_fac-A_C PF08646.10 KXG52733.1 - 0.053 13.3 0.4 0.071 12.9 0.4 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-BED PF02892.15 KXG52733.1 - 0.061 13.4 3.2 0.82 9.7 0.5 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 KXG52733.1 - 0.13 12.8 4.1 2 9.0 0.6 2.3 1 1 1 2 2 2 0 Zinc-finger double domain C1_2 PF03107.16 KXG52733.1 - 0.31 11.4 1.9 2.6 8.4 2.1 1.9 1 1 1 2 2 2 0 C1 domain zf-C2H2 PF00096.26 KXG52733.1 - 0.97 10.0 3.9 16 6.2 0.5 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type PHD PF00628.29 KXG52734.1 - 1.2e-09 37.9 5.2 2e-09 37.2 5.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXG52734.1 - 6.5e-05 22.4 1.6 0.00012 21.6 1.6 1.4 1 0 0 1 1 1 1 PHD-finger UvrA_inter PF17760.1 KXG52734.1 - 0.032 14.3 1.0 0.058 13.5 1.0 1.3 1 0 0 1 1 1 0 UvrA interaction domain Prok-RING_1 PF14446.6 KXG52734.1 - 0.45 10.5 1.9 0.86 9.6 1.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Glyco_hydro_15 PF00723.21 KXG52735.1 - 1.1e-104 350.7 0.4 1.3e-104 350.5 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Fungal_trans PF04082.18 KXG52736.1 - 3.1e-15 55.9 0.4 5.3e-15 55.2 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KXG52737.1 - 5.2e-58 196.4 0.5 6.1e-58 196.1 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG52737.1 - 3.8e-47 160.3 1.4 4.7e-47 160.0 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Abhydrolase_3 PF07859.13 KXG52738.1 - 6.3e-44 150.4 0.0 8e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXG52738.1 - 3.2e-10 39.5 0.7 9.9e-10 37.9 0.7 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KXG52738.1 - 2.4e-06 28.3 1.2 3.9e-06 27.6 1.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KXG52738.1 - 0.083 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KXG52738.1 - 0.12 11.9 0.0 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family EnY2 PF10163.9 KXG52739.1 - 7.7e-06 26.2 0.0 1.4e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 SAM_2 PF07647.17 KXG52740.1 - 6.7e-14 51.8 0.0 1.4e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KXG52740.1 - 3.2e-13 50.1 0.0 6.2e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.30 KXG52740.1 - 1.4e-12 47.8 0.0 2.5e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_4 PF18017.1 KXG52740.1 - 0.095 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Fungal_trans PF04082.18 KXG52741.1 - 2.5e-21 75.9 0.2 5.7e-21 74.7 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.12 KXG52742.1 - 2.4e-30 104.6 0.5 4.5e-30 103.7 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG52742.1 - 1.8e-19 70.0 0.5 3.1e-19 69.2 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXG52742.1 - 9.9e-09 35.0 0.0 1.7e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXG52742.1 - 9e-05 23.5 0.0 0.00026 22.0 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KXG52742.1 - 0.019 14.2 0.1 0.028 13.7 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXG52742.1 - 0.021 14.2 0.2 0.035 13.4 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KXG52742.1 - 0.095 13.1 0.1 0.17 12.4 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Sugar_tr PF00083.24 KXG52743.1 - 1.7e-98 330.4 23.8 2.1e-98 330.2 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG52743.1 - 3e-38 131.7 41.3 4.3e-33 114.7 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SPT_ssu-like PF11779.8 KXG52743.1 - 0.0031 17.1 2.0 0.011 15.3 2.0 2.0 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like TRI12 PF06609.13 KXG52743.1 - 0.012 14.0 7.5 0.1 11.0 2.3 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) AT_hook PF02178.19 KXG52744.1 - 2.3 8.4 13.3 0.18 11.8 3.5 3.2 2 0 0 2 2 2 0 AT hook motif Polysacc_deac_1 PF01522.21 KXG52745.1 - 4.5e-31 107.3 0.0 7.8e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KXG52745.1 - 4.6e-06 27.0 44.3 1.3e-05 25.5 14.4 2.9 2 1 0 2 2 2 2 Chitin recognition protein Glyco_hydro_57 PF03065.15 KXG52745.1 - 0.055 12.7 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Adaptin_N PF01602.20 KXG52746.1 - 0.0015 17.2 1.4 0.11 11.0 0.2 2.7 2 1 1 3 3 3 2 Adaptin N terminal region HEAT_2 PF13646.6 KXG52746.1 - 0.002 18.5 1.9 0.05 14.0 0.1 3.1 2 2 0 2 2 2 1 HEAT repeats HEAT PF02985.22 KXG52746.1 - 0.0024 18.0 1.2 1.5 9.3 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat Vac14_Fab1_bd PF12755.7 KXG52746.1 - 0.0052 17.3 0.1 0.019 15.5 0.0 1.9 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 KXG52746.1 - 0.0081 16.3 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 DRIM PF07539.12 KXG52746.1 - 0.017 13.5 2.0 0.6 8.3 0.2 2.1 1 1 1 2 2 2 0 Down-regulated in metastasis Cnd3 PF12719.7 KXG52746.1 - 0.018 14.3 0.1 0.04 13.1 0.0 1.5 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Fungal_trans_2 PF11951.8 KXG52748.1 - 1.5e-12 47.0 0.1 1.9e-12 46.7 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Oxidored_molyb PF00174.19 KXG52749.1 - 3.1e-55 186.4 0.0 5.5e-55 185.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KXG52749.1 - 4.2e-30 104.6 0.1 8.1e-30 103.6 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 KXG52749.1 - 7.6e-24 84.5 0.0 7.6e-24 84.5 0.0 2.5 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXG52749.1 - 1.8e-21 76.4 0.0 3.7e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KXG52749.1 - 1.1e-16 60.7 0.0 2.6e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KXG52749.1 - 0.00039 20.6 0.0 0.0033 17.6 0.0 2.4 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Hid1 PF12722.7 KXG52749.1 - 6.7 4.7 8.2 11 4.1 8.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_S49_N PF08496.10 KXG52749.1 - 7 6.7 8.5 0.56 10.3 0.4 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal TRAM_LAG1_CLN8 PF03798.16 KXG52750.1 - 2.5e-39 135.1 19.8 2.5e-39 135.1 19.8 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KXG52750.1 - 1.3e-24 85.6 0.1 3.4e-24 84.3 0.1 1.7 1 0 0 1 1 1 1 TRAM1-like protein Sugar_tr PF00083.24 KXG52751.1 - 3.1e-111 372.4 20.9 3.7e-111 372.2 20.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG52751.1 - 3.1e-28 98.7 44.8 1e-24 87.1 19.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 KXG52751.1 - 0.00035 19.6 0.5 0.00071 18.6 0.5 1.5 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM PapD_N PF00345.20 KXG52752.1 - 0.08 12.8 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain RNase_T PF00929.24 KXG52753.1 - 6e-07 30.2 0.0 7.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KXG52753.1 - 0.0033 17.1 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease DUF5051 PF16473.5 KXG52753.1 - 0.035 14.1 0.1 0.08 12.9 0.1 1.6 1 1 0 1 1 1 0 3' exoribonuclease, RNase T-like Glyco_hydro_43 PF04616.14 KXG52754.1 - 1.3e-71 241.3 2.0 1.6e-71 241.0 1.4 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXG52754.1 - 3.3e-11 43.3 0.0 6.7e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Sugar_tr PF00083.24 KXG52755.1 - 7e-72 242.7 23.3 8.2e-72 242.5 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG52755.1 - 4.8e-22 78.4 31.2 1.2e-15 57.3 11.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG52755.1 - 0.00019 20.0 3.7 0.00039 19.0 3.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sulfatase PF00884.23 KXG52756.1 - 1.3e-25 90.5 0.7 2.1e-25 89.8 0.7 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXG52756.1 - 0.00034 20.3 2.0 0.00099 18.8 1.9 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KXG52756.1 - 0.039 12.6 0.1 0.055 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KXG52756.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily Transglut_core PF01841.19 KXG52758.1 - 9.1e-13 48.6 0.0 1.6e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 KXG52758.1 - 0.044 13.3 0.0 0.53 9.8 0.0 2.3 1 1 0 1 1 1 0 Transglutaminase-like domain Ras PF00071.22 KXG52759.1 - 4.9e-31 107.5 0.2 6.6e-31 107.1 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXG52759.1 - 1.6e-23 83.2 0.1 2.8e-23 82.4 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG52759.1 - 1.4e-06 27.9 0.1 2.1e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXG52759.1 - 0.00028 20.3 0.2 0.00039 19.8 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KXG52759.1 - 0.013 14.4 0.1 2.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 KXG52759.1 - 0.067 12.3 0.6 0.64 9.1 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit CAF1C_H4-bd PF12265.8 KXG52760.1 - 4.2e-17 62.2 0.1 5.4e-16 58.6 0.0 2.7 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KXG52760.1 - 6.2e-15 55.3 8.7 1.3e-06 29.0 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG52760.1 - 9.9e-09 35.4 2.0 0.00059 20.1 0.2 3.4 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans PF04082.18 KXG52761.1 - 7.8e-24 84.1 1.8 1.3e-23 83.4 1.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXG52761.1 - 1.5e-09 37.8 12.6 0.00026 21.3 4.0 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXG52761.1 - 5.3e-08 32.9 11.9 9.1e-07 29.0 5.8 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXG52761.1 - 0.0072 17.1 18.9 0.058 14.3 3.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger Patatin PF01734.22 KXG52761.1 - 0.062 13.5 0.8 0.28 11.3 0.1 2.4 2 0 0 2 2 2 0 Patatin-like phospholipase zf-C2H2_6 PF13912.6 KXG52761.1 - 0.11 12.6 3.8 0.34 10.9 3.8 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXG52761.1 - 0.25 11.7 2.0 0.83 10.0 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KXG52761.1 - 2.3 8.1 8.0 10 6.0 1.5 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type Condensation PF00668.20 KXG52762.1 - 0 1310.5 0.0 1.5e-52 178.8 0.0 10.1 9 2 0 9 9 9 9 Condensation domain AMP-binding PF00501.28 KXG52762.1 - 0 1283.4 0.0 4.8e-84 282.4 0.0 5.3 5 0 0 5 5 5 5 AMP-binding enzyme PP-binding PF00550.25 KXG52762.1 - 3.6e-68 225.8 0.0 1.9e-13 50.6 0.0 6.2 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXG52762.1 - 1.4e-08 35.6 0.1 0.56 11.2 0.0 5.6 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KXG52762.1 - 0.0047 15.6 0.0 4.7 5.7 0.0 3.6 5 0 0 5 5 5 2 Transferase family TFIID_20kDa PF03847.13 KXG52762.1 - 0.011 16.2 0.2 4.4 7.9 0.0 3.6 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A ketoacyl-synt PF00109.26 KXG52763.1 - 6.3e-77 258.6 0.1 1.6e-76 257.2 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXG52763.1 - 2.4e-62 210.0 0.8 6.4e-62 208.7 0.4 2.0 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KXG52763.1 - 3.1e-52 177.7 0.0 5.4e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXG52763.1 - 1.7e-50 172.4 0.0 3.3e-50 171.4 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXG52763.1 - 2.7e-36 124.2 0.2 6.2e-36 123.0 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXG52763.1 - 7.3e-15 55.4 0.0 2.6e-14 53.6 0.0 2.0 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KXG52763.1 - 0.00023 20.7 0.0 0.00046 19.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG52763.1 - 0.00059 19.5 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KXG52763.1 - 0.001 18.5 0.4 0.0027 17.1 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain PP-binding PF00550.25 KXG52763.1 - 0.0013 19.0 0.0 0.0032 17.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAT PF16073.5 KXG52763.1 - 0.0064 16.3 2.6 0.016 14.9 2.6 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 KXG52763.1 - 0.0086 15.9 0.2 0.031 14.1 0.2 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ABC_tran PF00005.27 KXG52764.1 - 3.4e-50 170.1 0.5 2.6e-28 99.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXG52764.1 - 7e-32 111.2 29.2 1.8e-25 90.1 13.5 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.6 KXG52764.1 - 1.2e-09 37.7 1.5 0.00059 19.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KXG52764.1 - 1.4e-09 38.2 1.7 0.12 12.1 0.0 4.3 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXG52764.1 - 1.2e-06 28.5 1.1 0.045 13.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KXG52764.1 - 1.8e-06 28.3 2.9 0.053 13.8 0.2 3.2 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KXG52764.1 - 2e-06 28.4 1.0 0.004 17.7 0.1 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KXG52764.1 - 7.8e-06 25.5 2.3 0.031 13.7 0.2 4.0 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 KXG52764.1 - 1.1e-05 24.7 0.3 0.073 12.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 KXG52764.1 - 1.4e-05 25.6 0.1 0.064 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KXG52764.1 - 4.3e-05 23.2 0.0 0.42 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXG52764.1 - 6.7e-05 23.4 0.5 0.16 12.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 KXG52764.1 - 0.0002 21.5 2.7 0.65 10.1 0.4 3.0 2 1 0 2 2 2 2 AAA domain cobW PF02492.19 KXG52764.1 - 0.00022 20.9 3.9 0.043 13.4 1.1 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KXG52764.1 - 0.00022 21.0 0.3 0.4 10.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KXG52764.1 - 0.00023 21.2 0.7 0.43 10.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXG52764.1 - 0.00036 20.6 3.0 0.046 13.8 0.4 2.4 2 0 0 2 2 2 1 Dynamin family AAA_15 PF13175.6 KXG52764.1 - 0.00057 19.7 0.1 0.67 9.6 0.1 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 KXG52764.1 - 0.00059 19.4 0.3 0.82 9.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_19 PF13245.6 KXG52764.1 - 0.00061 20.2 0.3 0.34 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KXG52764.1 - 0.0011 18.7 0.6 0.039 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KXG52764.1 - 0.0012 18.8 2.8 0.11 12.3 0.0 2.9 3 0 0 3 3 3 1 NTPase FtsK_SpoIIIE PF01580.18 KXG52764.1 - 0.0015 17.9 0.1 0.3 10.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family ABC_ATPase PF09818.9 KXG52764.1 - 0.0029 16.5 0.5 0.31 9.8 0.4 3.5 4 0 0 4 4 4 1 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 KXG52764.1 - 0.0056 16.4 0.6 2.7 7.7 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein ATPase_2 PF01637.18 KXG52764.1 - 0.014 15.3 0.1 0.73 9.7 0.1 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA PF00004.29 KXG52764.1 - 0.02 15.3 0.5 17 5.9 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KXG52764.1 - 0.02 14.6 0.4 1 9.0 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase SbcCD_C PF13558.6 KXG52764.1 - 0.022 15.0 0.3 14 6.0 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Adeno_IVa2 PF02456.15 KXG52764.1 - 0.023 13.5 0.7 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein GTP_EFTU PF00009.27 KXG52764.1 - 0.024 14.2 0.1 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 KXG52764.1 - 0.024 13.8 1.2 1.6 7.8 0.2 2.6 2 1 0 2 2 2 0 NB-ARC domain Rad17 PF03215.15 KXG52764.1 - 0.025 14.5 0.2 8.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 KXG52764.1 - 0.028 14.3 1.3 2.5 8.0 0.2 2.6 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 KXG52764.1 - 0.033 14.4 2.7 1.4 9.2 0.0 3.1 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KXG52764.1 - 0.037 13.3 1.1 1.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.18 KXG52764.1 - 0.042 13.1 0.5 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Septin TrwB_AAD_bind PF10412.9 KXG52764.1 - 0.063 12.2 2.5 0.51 9.2 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.17 KXG52764.1 - 0.068 12.9 0.5 11 5.8 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 KXG52764.1 - 0.077 13.4 0.6 6 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 KXG52764.1 - 0.095 12.7 1.5 29 4.7 0.3 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KXG52764.1 - 0.12 12.4 0.1 22 5.1 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KXG52764.1 - 0.17 11.9 0.4 7.7 6.6 0.1 3.1 3 0 0 3 3 3 0 AAA domain PRK PF00485.18 KXG52764.1 - 0.22 11.2 0.3 0.44 10.2 0.1 1.6 2 0 0 2 2 1 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 KXG52764.1 - 0.23 11.5 3.4 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain MobB PF03205.14 KXG52764.1 - 0.27 11.1 1.7 4.9 7.1 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 KXG52764.1 - 1.8 8.8 5.8 2.5 8.3 0.2 2.4 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 KXG52764.1 - 2.7 7.8 3.6 4.8 7.0 0.5 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Clathrin PF00637.20 KXG52766.1 - 4.8e-25 88.1 0.8 5.7e-22 78.1 1.1 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.8 KXG52766.1 - 1.5e-18 66.7 0.7 3.4e-18 65.6 0.7 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KXG52766.1 - 8.1e-08 32.2 7.4 1.5e-07 31.3 7.4 1.5 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 KXG52766.1 - 1.7e-06 27.8 7.1 3.5e-06 26.8 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.6 KXG52766.1 - 5.2e-06 26.8 0.1 0.023 15.5 0.0 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat zf-RING_5 PF14634.6 KXG52766.1 - 0.00016 21.5 5.8 0.00033 20.5 5.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.6 KXG52766.1 - 0.00063 19.4 0.1 0.0023 17.6 0.1 2.0 1 0 0 1 1 1 1 TPR repeat zf-RING_2 PF13639.6 KXG52766.1 - 0.0013 19.0 6.6 0.0024 18.1 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXG52766.1 - 0.0071 16.6 4.7 0.014 15.7 4.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain DUF4810 PF16068.5 KXG52766.1 - 0.0079 16.7 0.5 3.3 8.3 0.0 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4810) TPR_16 PF13432.6 KXG52766.1 - 0.015 15.9 0.1 0.12 13.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Katanin_con80 PF13925.6 KXG52766.1 - 0.021 14.9 0.0 2.1 8.4 0.0 3.1 3 0 0 3 3 3 0 con80 domain of Katanin zf-C3HC4 PF00097.25 KXG52766.1 - 0.037 13.9 5.7 0.069 13.0 5.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 KXG52766.1 - 0.049 14.1 3.7 0.32 11.5 3.7 2.3 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-ANAPC11 PF12861.7 KXG52766.1 - 0.4 10.8 1.9 0.94 9.6 1.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_12 PF13424.6 KXG52766.1 - 0.74 10.1 2.5 0.78 10.1 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG52766.1 - 0.88 9.8 3.2 1.9 8.8 0.1 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KXG52766.1 - 1.3 9.4 6.0 0.25 11.5 0.3 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 KXG52766.1 - 1.6 8.8 7.5 3.8 7.6 7.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Nha1_C PF08619.10 KXG52767.1 - 2.6e-103 346.7 47.8 2.6e-103 346.7 47.8 1.4 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 KXG52767.1 - 8e-77 258.6 15.4 9.5e-77 258.3 15.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Serglycin PF04360.12 KXG52767.1 - 0.098 12.6 6.6 0.2 11.6 6.6 1.5 1 0 0 1 1 1 0 Serglycin Diacid_rec PF05651.13 KXG52767.1 - 0.21 11.3 1.1 0.35 10.5 0.0 1.9 2 0 0 2 2 2 0 Putative sugar diacid recognition DUF21 PF01595.20 KXG52767.1 - 0.57 9.9 5.6 0.11 12.1 1.5 2.0 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain YrhC PF14143.6 KXG52767.1 - 0.66 10.1 2.0 0.77 9.9 0.3 2.0 2 0 0 2 2 2 0 YrhC-like protein PX PF00787.24 KXG52768.1 - 2.7e-17 62.8 0.2 6e-17 61.7 0.2 1.6 1 0 0 1 1 1 1 PX domain Tmemb_cc2 PF10267.9 KXG52768.1 - 0.0089 15.2 0.3 0.014 14.6 0.3 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Prefoldin_3 PF13758.6 KXG52768.1 - 0.025 14.6 1.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit Zn_clus PF00172.18 KXG52769.1 - 5.4e-08 32.8 8.1 1.1e-07 31.9 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXG52769.1 - 2.5e-05 23.5 0.4 3.9e-05 22.8 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sua5_yciO_yrdC PF01300.18 KXG52770.1 - 2.3e-13 50.0 0.0 2.8e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination MFS_1 PF07690.16 KXG52771.1 - 3.8e-05 22.8 2.6 4.5e-05 22.5 2.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Aldedh PF00171.22 KXG52774.1 - 6.4e-102 341.4 0.0 7.7e-102 341.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.18 KXG52775.1 - 4.2e-62 210.3 0.2 5.1e-62 210.1 0.2 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Fungal_trans PF04082.18 KXG52776.1 - 1.7e-12 47.0 0.0 2.9e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG52776.1 - 0.0057 16.8 4.3 0.0099 16.0 4.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG2_CAD PF13329.6 KXG52776.1 - 0.044 13.5 0.3 0.08 12.7 0.3 1.3 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif DUF3530 PF12048.8 KXG52776.1 - 0.14 11.5 0.2 0.22 10.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) NAD_binding_10 PF13460.6 KXG52777.1 - 2.8e-16 59.9 0.0 5.2e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXG52777.1 - 3.9e-12 46.2 0.0 5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 KXG52777.1 - 0.22 11.6 0.0 0.41 10.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.18 KXG52778.1 - 5.9e-24 84.5 0.1 8.4e-24 84.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 KXG52778.1 - 4e-06 26.9 0.3 8.4e-06 25.9 0.3 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain Ank_2 PF12796.7 KXG52781.1 - 1.3e-82 272.4 0.4 5.6e-18 65.3 0.0 7.8 3 1 4 8 8 8 6 Ankyrin repeats (3 copies) Ank PF00023.30 KXG52781.1 - 4.8e-71 232.3 0.0 3.5e-06 27.2 0.0 13.6 13 0 0 13 13 13 11 Ankyrin repeat Ank_3 PF13606.6 KXG52781.1 - 5.2e-63 201.5 0.7 0.00016 21.9 0.0 13.8 13 0 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.6 KXG52781.1 - 7.3e-58 192.2 0.0 2.8e-10 40.5 0.0 8.4 6 2 2 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG52781.1 - 7.7e-34 115.3 6.4 0.00021 21.5 0.0 9.7 4 1 7 11 11 11 9 Ankyrin repeats (many copies) AAA_16 PF13191.6 KXG52781.1 - 8.1e-07 29.6 0.0 6.7e-06 26.6 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain PNP_UDP_1 PF01048.20 KXG52781.1 - 1.9e-06 27.3 0.0 5e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KXG52781.1 - 0.00026 20.9 0.0 0.00085 19.3 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXG52781.1 - 0.00077 19.8 0.0 0.0026 18.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXG52781.1 - 0.006 16.2 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXG52781.1 - 0.015 15.7 0.0 0.048 14.1 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) LisH PF08513.11 KXG52781.1 - 0.095 12.7 0.0 0.31 11.0 0.0 2.0 1 0 0 1 1 1 0 LisH KAP_NTPase PF07693.14 KXG52781.1 - 0.15 11.3 0.1 0.93 8.7 0.0 2.0 2 1 1 3 3 3 0 KAP family P-loop domain PEGA PF08308.11 KXG52781.1 - 0.16 11.9 0.0 27 4.7 0.0 4.2 5 0 0 5 5 5 0 PEGA domain VWA_3_C PF18571.1 KXG52781.1 - 0.17 11.8 1.4 1.6e+02 2.2 0.0 4.8 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain Flavin_Reduct PF01613.18 KXG52782.1 - 5.9e-15 55.6 0.0 8.3e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Putative_PNPOx PF01243.20 KXG52782.1 - 0.02 15.1 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase EFP_N PF08207.12 KXG52782.1 - 0.12 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Syndecan PF01034.20 KXG52783.1 - 0.014 15.2 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Syndecan domain ASFV_J13L PF05568.11 KXG52783.1 - 0.016 15.0 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein TMEM154 PF15102.6 KXG52783.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Stevor PF17410.2 KXG52783.1 - 0.037 13.6 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame VKOR PF07884.14 KXG52783.1 - 0.047 13.9 0.0 0.055 13.7 0.0 1.1 1 0 0 1 1 1 0 Vitamin K epoxide reductase family DUF485 PF04341.12 KXG52783.1 - 0.061 13.3 0.0 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF485 EphA2_TM PF14575.6 KXG52783.1 - 0.077 13.9 0.0 0.14 13.1 0.0 1.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 KXG52783.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family AAA PF00004.29 KXG52784.1 - 3.6e-08 33.9 0.1 2.6e-07 31.1 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXG52784.1 - 3.1e-05 24.4 0.0 7.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KXG52784.1 - 0.0003 21.4 0.1 0.0012 19.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXG52784.1 - 0.00085 19.6 0.0 0.0029 17.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KXG52784.1 - 0.0015 18.5 0.1 0.17 11.8 0.0 3.1 3 0 0 3 3 3 1 Rad17 P-loop domain T2SSE PF00437.20 KXG52784.1 - 0.0053 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein TIP49 PF06068.13 KXG52784.1 - 0.015 14.5 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Cytidylate_kin PF02224.18 KXG52784.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_7 PF12775.7 KXG52784.1 - 0.06 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KXG52784.1 - 0.098 12.4 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KXG52784.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KXG52784.1 - 0.11 11.7 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AT_hook PF02178.19 KXG52784.1 - 4.9 7.4 8.9 0.29 11.1 3.0 2.3 2 0 0 2 2 1 0 AT hook motif Utp8 PF10395.9 KXG52785.1 - 9e-10 37.7 2.8 2.2e-09 36.4 2.8 1.6 1 1 0 1 1 1 1 Utp8 family LRR_4 PF12799.7 KXG52786.1 - 3.3e-25 87.7 39.2 4.1e-05 23.9 0.1 9.2 4 2 7 12 12 12 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXG52786.1 - 7e-22 77.0 35.2 2e-06 27.5 2.7 7.5 5 2 3 8 8 8 5 Leucine rich repeat LRR_9 PF14580.6 KXG52786.1 - 7e-08 32.2 13.5 0.028 13.9 1.0 4.6 1 1 2 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KXG52786.1 - 1.5e-07 30.9 27.1 0.57 10.4 0.0 9.6 10 0 0 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.33 KXG52786.1 - 0.00014 21.9 28.1 4.4 8.3 0.0 10.7 9 3 0 9 9 9 2 Leucine Rich Repeat Cupin_1 PF00190.22 KXG52787.1 - 2.9e-39 134.1 0.0 1.1e-19 70.5 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KXG52787.1 - 1.9e-22 78.7 2.3 3.8e-10 39.3 0.1 3.2 4 0 0 4 4 4 2 Cupin domain Cupin_3 PF05899.12 KXG52787.1 - 2.2e-05 24.1 0.1 0.044 13.5 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF861) 3-HAO PF06052.12 KXG52787.1 - 0.00037 20.2 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 2 3-hydroxyanthranilic acid dioxygenase AraC_binding PF02311.19 KXG52787.1 - 0.0019 18.1 0.4 1.4 8.8 0.2 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_4 PF08007.12 KXG52787.1 - 0.0069 15.9 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein SBP56 PF05694.11 KXG52788.1 - 7.1e-08 31.7 0.0 9.5e-06 24.7 0.0 2.8 2 1 0 2 2 2 2 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 KXG52788.1 - 0.0094 15.2 0.3 0.83 8.8 0.9 2.8 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 KXG52788.1 - 0.027 14.1 0.0 3.2 7.3 0.0 3.1 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KXG52788.1 - 0.074 13.1 0.0 26 5.1 0.0 3.1 3 0 0 3 3 3 0 NHL repeat MFS_1 PF07690.16 KXG52789.1 - 6.4e-28 97.7 52.7 2.9e-27 95.5 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PepSY_TM_like_2 PF16357.5 KXG52789.1 - 0.011 15.7 0.1 0.031 14.2 0.1 1.7 1 0 0 1 1 1 0 Putative PepSY_TM-like TraL PF07178.11 KXG52789.1 - 2.5 8.6 10.8 7.6 7.1 0.4 3.6 3 0 0 3 3 3 0 TraL protein DAO PF01266.24 KXG52790.1 - 2.1e-42 146.0 0.0 3.1e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pkinase PF00069.25 KXG52790.1 - 1.7e-11 44.0 0.0 1.7e-10 40.8 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG52790.1 - 0.0029 16.9 0.0 0.027 13.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase NAD_binding_8 PF13450.6 KXG52790.1 - 0.0033 17.6 0.3 0.0099 16.1 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 KXG52790.1 - 0.089 11.6 1.0 0.23 10.2 0.0 2.1 3 0 0 3 3 3 0 MCRA family MFS_1 PF07690.16 KXG52792.1 - 4.4e-30 104.8 22.7 4.4e-30 104.8 22.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXG52792.1 - 0.0012 18.5 2.2 0.0031 17.2 2.2 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Chordopox_L2 PF05803.12 KXG52792.1 - 0.3 11.0 1.3 0.73 9.7 1.3 1.6 1 1 0 1 1 1 0 Chordopoxvirus L2 protein ERM PF00769.19 KXG52793.1 - 0.00059 19.7 3.6 0.00083 19.3 3.6 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Cep57_CLD_2 PF14197.6 KXG52793.1 - 0.0007 19.6 4.8 0.0034 17.4 2.2 2.4 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 THP2 PF09432.10 KXG52793.1 - 0.0014 18.7 0.2 0.0026 17.8 0.2 1.4 1 0 0 1 1 1 1 Tho complex subunit THP2 ZapB PF06005.12 KXG52793.1 - 0.0027 18.1 2.5 0.0061 17.0 2.5 1.6 1 0 0 1 1 1 1 Cell division protein ZapB UPF0242 PF06785.11 KXG52793.1 - 0.0029 17.7 2.8 0.0041 17.3 2.8 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus HEPN_AbiU2 PF18734.1 KXG52793.1 - 0.0048 16.4 0.4 0.0071 15.9 0.4 1.3 1 0 0 1 1 1 1 AbiU2 KASH_CCD PF14662.6 KXG52793.1 - 0.0049 16.7 1.1 0.0049 16.7 1.1 1.5 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH DUF4686 PF15742.5 KXG52793.1 - 0.0074 15.5 3.0 0.01 15.0 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) Chromo PF00385.24 KXG52793.1 - 0.015 15.2 0.3 0.03 14.2 0.3 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Syntaxin-6_N PF09177.11 KXG52793.1 - 0.015 15.8 0.8 0.025 15.1 0.8 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal FlxA PF14282.6 KXG52793.1 - 0.016 15.2 0.4 0.027 14.4 0.4 1.4 1 0 0 1 1 1 0 FlxA-like protein DHR10 PF18595.1 KXG52793.1 - 0.02 14.9 3.9 0.035 14.2 3.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF3450 PF11932.8 KXG52793.1 - 0.029 13.7 1.5 0.041 13.2 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Tom37_C PF11801.8 KXG52793.1 - 0.03 14.3 0.1 0.27 11.2 0.0 2.1 1 1 0 2 2 2 0 Tom37 C-terminal domain DUF4407 PF14362.6 KXG52793.1 - 0.041 13.2 2.1 0.052 12.9 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KXG52793.1 - 0.048 14.2 4.8 0.069 13.7 4.8 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1192 PF06698.11 KXG52793.1 - 0.05 13.7 3.5 0.29 11.2 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) STAT_alpha PF01017.20 KXG52793.1 - 0.051 13.5 0.9 0.082 12.8 0.9 1.3 1 0 0 1 1 1 0 STAT protein, all-alpha domain T3SSipB PF16535.5 KXG52793.1 - 0.096 13.2 0.4 0.14 12.7 0.4 1.2 1 0 0 1 1 1 0 Type III cell invasion protein SipB GreA_GreB_N PF03449.15 KXG52793.1 - 0.12 12.5 6.4 0.82 9.9 1.8 2.4 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal DivIC PF04977.15 KXG52793.1 - 0.16 11.7 6.1 0.64 9.8 1.7 2.2 1 1 1 2 2 2 0 Septum formation initiator YabA PF06156.13 KXG52793.1 - 0.16 12.6 0.5 0.3 11.7 0.5 1.4 1 0 0 1 1 1 0 Initiation control protein YabA bZIP_1 PF00170.21 KXG52793.1 - 0.27 11.3 3.3 4 7.6 0.2 2.3 1 1 1 2 2 2 0 bZIP transcription factor Wbp11 PF09429.10 KXG52793.1 - 0.41 11.1 3.4 0.64 10.5 2.8 1.7 1 1 0 1 1 1 0 WW domain binding protein 11 HalX PF08663.10 KXG52793.1 - 0.45 10.9 7.1 5 7.5 0.3 2.7 1 1 1 2 2 2 0 HalX domain Methyltransf_23 PF13489.6 KXG52794.1 - 5.7e-09 36.0 0.0 8.3e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG52794.1 - 1.3e-05 25.8 0.0 4.7e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXG52794.1 - 0.0016 18.0 0.1 0.007 15.9 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 KXG52794.1 - 0.03 13.6 0.0 0.31 10.3 0.0 2.4 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KXG52794.1 - 0.038 13.8 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXG52794.1 - 0.13 13.0 0.0 0.83 10.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain TIP120 PF08623.10 KXG52795.1 - 3.4e-63 212.4 0.5 2.1e-62 209.8 0.1 2.5 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 KXG52795.1 - 2.4e-06 27.3 12.7 0.87 10.0 0.0 8.6 11 0 0 11 11 11 2 HEAT repeat HEAT_2 PF13646.6 KXG52795.1 - 6.6e-06 26.4 6.2 2.9 8.4 0.0 6.4 4 2 3 7 7 7 2 HEAT repeats IFRD PF05004.13 KXG52795.1 - 0.0039 16.3 1.3 0.95 8.5 0.0 3.3 3 1 0 3 3 3 2 Interferon-related developmental regulator (IFRD) UNC45-central PF11701.8 KXG52795.1 - 0.044 13.7 2.1 35 4.3 0.1 4.2 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.6 KXG52795.1 - 0.05 14.1 15.8 1 10.0 0.1 7.5 6 2 2 8 8 8 0 HEAT-like repeat Arm PF00514.23 KXG52795.1 - 0.081 13.0 0.8 5.7 7.1 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 KXG52795.1 - 0.1 12.9 0.0 1.8 8.9 0.0 2.9 1 1 1 2 2 2 0 TAF6 C-terminal HEAT repeat domain PSY3 PF16836.5 KXG52795.1 - 0.19 11.2 0.0 0.47 9.9 0.0 1.6 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description HEAT_PBS PF03130.16 KXG52795.1 - 7.9 7.5 8.3 2.4 9.1 0.5 4.3 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DBR1 PF05011.13 KXG52796.1 - 1.2e-38 132.7 0.0 2.5e-38 131.6 0.0 1.6 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain API5 PF05918.11 KXG52796.1 - 5.9 5.6 4.5 3.2 6.4 1.1 1.9 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) RTP1_C1 PF10363.9 KXG52797.1 - 5.7e-29 100.6 0.0 6e-28 97.3 0.0 2.8 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KXG52797.1 - 2.7e-06 26.9 0.0 1.4e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 2 MscS_TM PF12794.7 KXG52797.1 - 0.2 10.5 2.1 0.35 9.7 2.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 HEAT_EZ PF13513.6 KXG52797.1 - 0.44 11.1 7.7 14 6.3 0.0 4.9 4 1 0 4 4 4 0 HEAT-like repeat zf-ZPR1 PF03367.13 KXG52798.1 - 6e-102 338.2 0.0 6.6e-53 178.8 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 KXG52798.1 - 0.033 14.2 0.5 0.53 10.3 0.0 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA APH PF01636.23 KXG52798.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FeS PF04060.13 KXG52798.1 - 0.08 12.6 0.8 0.19 11.4 0.8 1.7 1 0 0 1 1 1 0 Putative Fe-S cluster ABC_membrane PF00664.23 KXG52799.1 - 1.2e-34 120.2 13.5 2e-34 119.5 13.5 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXG52799.1 - 7.2e-33 114.0 0.0 1.4e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KXG52799.1 - 1.5e-07 31.1 0.0 1.4e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KXG52799.1 - 0.0067 16.6 0.3 0.24 11.7 0.3 2.8 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KXG52799.1 - 0.0085 15.8 0.1 0.022 14.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KXG52799.1 - 0.064 13.6 0.1 0.17 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KXG52799.1 - 0.072 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KXG52799.1 - 0.12 12.7 0.3 1.5 9.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KXG52799.1 - 0.17 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain APH PF01636.23 KXG52800.1 - 2.1e-17 63.8 0.3 3.2e-10 40.3 0.0 3.1 2 1 0 2 2 2 2 Phosphotransferase enzyme family Glycos_transf_1 PF00534.20 KXG52800.1 - 1.2e-09 37.9 0.0 2.4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXG52800.1 - 3.9e-09 37.1 0.0 9.9e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Choline_kinase PF01633.20 KXG52800.1 - 0.00038 20.1 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 2 Choline/ethanolamine kinase WaaY PF06176.11 KXG52800.1 - 0.09 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pro_isomerase PF00160.21 KXG52801.1 - 1.8e-35 122.5 0.0 5.1e-35 121.1 0.0 1.6 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ORC6 PF05460.13 KXG52802.1 - 7.2e-93 311.7 0.0 8.4e-93 311.5 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Augurin PF15187.6 KXG52802.1 - 0.12 12.6 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 Oesophageal cancer-related gene 4 Spc7_N PF15402.6 KXG52802.1 - 1.1 7.4 11.8 1.5 6.9 11.8 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Q_salvage PF10343.9 KXG52803.1 - 6e-135 449.3 0.0 7.7e-135 448.9 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF4121 PF13497.6 KXG52803.1 - 0.048 12.8 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) DUF1563 PF07599.11 KXG52803.1 - 0.084 13.0 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) ThiF PF00899.21 KXG52804.1 - 3.4e-67 226.3 1.6 1.3e-36 126.3 0.2 2.1 2 0 0 2 2 2 2 ThiF family UAE_UbL PF14732.6 KXG52804.1 - 4.9e-18 65.5 0.6 1.3e-17 64.2 0.6 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KXG52804.1 - 3.5e-08 33.7 2.2 5e-06 26.6 0.8 2.4 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KXG52804.1 - 0.0011 19.4 0.1 0.0095 16.4 0.0 2.6 3 1 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KXG52804.1 - 0.0018 18.3 0.1 0.0081 16.2 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KXG52804.1 - 0.014 16.0 0.1 3.1 8.4 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase YfkB PF08756.10 KXG52804.1 - 0.069 12.9 0.1 3.7 7.3 0.0 2.4 2 0 0 2 2 2 0 YfkB-like domain Beta_helix PF13229.6 KXG52805.1 - 9.7e-17 61.3 17.0 3.7e-10 39.9 1.0 3.2 1 1 1 2 2 2 2 Right handed beta helix region DUF1080 PF06439.11 KXG52805.1 - 0.041 14.0 0.2 24 5.0 0.0 3.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1080) adh_short PF00106.25 KXG52806.1 - 7.9e-36 123.4 1.2 1.8e-25 89.6 0.1 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXG52806.1 - 8.4e-36 123.7 0.3 1.3e-30 106.7 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG52806.1 - 7.1e-11 42.3 1.0 1.1e-09 38.5 0.1 2.4 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 KXG52806.1 - 0.00014 21.4 0.0 0.00035 20.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXG52806.1 - 0.00031 20.0 0.1 0.011 14.8 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KXG52806.1 - 0.022 14.6 0.5 5.7 6.8 0.0 2.2 1 1 1 2 2 2 0 NAD(P)H-binding F420_oxidored PF03807.17 KXG52806.1 - 0.028 15.0 0.1 0.064 13.9 0.1 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KXG52806.1 - 0.08 13.0 0.0 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KXG52806.1 - 0.099 12.9 0.2 1 9.6 0.2 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Skp1_POZ PF03931.15 KXG52807.1 - 0.00022 21.3 0.4 0.00092 19.3 0.0 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain zf-C3HC4_3 PF13920.6 KXG52808.1 - 9.1e-09 35.1 11.9 1.5e-08 34.3 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXG52808.1 - 0.13 12.2 12.5 0.23 11.3 12.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Malic_M PF03949.15 KXG52809.1 - 5.1e-92 307.8 0.0 6.8e-92 307.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KXG52809.1 - 2.1e-65 220.0 0.7 4e-65 219.0 0.0 1.8 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain HNH_2 PF13391.6 KXG52810.1 - 0.00087 19.4 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease adh_short PF00106.25 KXG52811.1 - 0.017 14.6 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase adh_short_C2 PF13561.6 KXG52811.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase CFEM PF05730.11 KXG52812.1 - 1.6e-15 56.9 7.8 2.7e-15 56.2 7.8 1.4 1 0 0 1 1 1 1 CFEM domain Plasmodium_Vir PF05795.11 KXG52812.1 - 0.54 9.6 1.3 0.61 9.4 1.3 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF5437 PF17505.2 KXG52812.1 - 0.59 10.2 0.1 0.59 10.2 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5437) DNA_pol_delta_4 PF04081.13 KXG52813.1 - 6.5e-35 120.3 1.3 9e-35 119.9 1.3 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Arrestin_C PF02752.22 KXG52814.1 - 2.7e-06 27.9 0.6 1.7e-05 25.3 0.0 2.4 2 2 1 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Melibiase PF02065.18 KXG52816.1 - 2.2e-150 500.4 0.0 2.8e-150 500.1 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KXG52816.1 - 1.9e-81 273.4 0.0 3.2e-81 272.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 KXG52816.1 - 9.8e-23 80.4 0.0 2.5e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 KXG52816.1 - 8.1e-08 31.7 0.0 1.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 PALP PF00291.25 KXG52817.1 - 6.9e-46 157.0 3.3 8e-46 156.8 3.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme tRNA_int_end_N2 PF12928.7 KXG52818.1 - 9.4e-29 99.4 0.0 2.2e-28 98.2 0.0 1.7 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KXG52818.1 - 0.006 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain ThiF PF00899.21 KXG52819.1 - 5.7e-13 48.8 0.0 2.5e-12 46.7 0.0 2.1 1 1 0 1 1 1 1 ThiF family Rib_5-P_isom_A PF06026.14 KXG52820.1 - 1.6e-45 154.8 0.0 2.6e-45 154.1 0.0 1.3 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KXG52820.1 - 0.13 12.2 0.0 4.9 7.1 0.0 2.1 2 0 0 2 2 2 0 DeoR C terminal sensor domain WD40 PF00400.32 KXG52821.1 - 2.7e-15 56.5 0.6 0.04 14.8 0.3 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG52821.1 - 0.053 13.8 0.2 21 5.5 0.0 3.7 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain PSII_BNR PF14870.6 KXG52821.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 ATP_bind_1 PF03029.17 KXG52822.1 - 2.4e-78 263.3 0.0 2.9e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 KXG52822.1 - 0.00082 19.3 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KXG52822.1 - 0.0011 18.0 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KXG52822.1 - 0.0034 17.5 0.0 0.028 14.5 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KXG52822.1 - 0.019 15.2 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXG52822.1 - 0.032 14.5 0.0 0.067 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KXG52822.1 - 0.053 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_10 PF12846.7 KXG52822.1 - 0.073 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.6 KXG52822.1 - 0.085 13.4 0.1 0.24 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 KXG52822.1 - 0.11 12.0 0.4 0.46 9.9 0.1 2.1 2 1 1 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RNA_helicase PF00910.22 KXG52822.1 - 0.14 12.5 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 KXG52822.1 - 0.31 11.5 0.2 0.31 11.5 0.2 1.9 2 0 0 2 2 2 0 AAA domain RNase_P_Rpp14 PF01900.19 KXG52823.1 - 1.3e-36 125.0 0.0 1.9e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Rpp14/Pop5 family Citrate_bind PF16114.5 KXG52824.1 - 6.3e-87 289.7 0.1 8.6e-87 289.2 0.1 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KXG52824.1 - 1.5e-08 34.4 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain MBOAT_2 PF13813.6 KXG52825.1 - 2.4e-24 85.4 2.1 4.6e-24 84.5 0.4 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Fip1 PF05182.13 KXG52826.1 - 6.6e-20 70.4 1.3 1.2e-19 69.5 1.3 1.4 1 0 0 1 1 1 1 Fip1 motif Cpn10 PF00166.21 KXG52827.1 - 4.7e-29 100.3 0.0 5.3e-29 100.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit TauD PF02668.16 KXG52829.1 - 3e-53 181.4 0.3 3.9e-53 181.0 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Nucleoporin_FG PF13634.6 KXG52830.1 - 0.0001 23.1 42.4 0.0001 23.1 42.4 2.7 1 1 1 2 2 2 1 Nucleoporin FG repeat region DUF1664 PF07889.12 KXG52830.1 - 0.0079 16.2 0.6 0.44 10.6 0.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KXG52830.1 - 0.009 16.1 1.6 12 6.0 0.1 3.5 2 2 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.32 KXG52831.1 - 0.0003 21.5 6.6 10 7.2 2.5 4.8 4 1 0 4 4 4 3 WD domain, G-beta repeat Lactonase PF10282.9 KXG52831.1 - 0.00048 19.5 0.0 0.00078 18.8 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller ANAPC4_WD40 PF12894.7 KXG52831.1 - 0.015 15.6 0.0 0.48 10.8 0.0 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain HAD_2 PF13419.6 KXG52832.1 - 1.4e-13 51.3 0.0 2.2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXG52832.1 - 3.2e-07 30.8 0.0 9e-05 22.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIR_SIR PF01077.22 KXG52832.1 - 0.0035 16.9 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Hydrolase_like PF13242.6 KXG52832.1 - 0.0077 16.3 0.0 0.025 14.7 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like TPR_1 PF00515.28 KXG52833.1 - 4e-07 29.6 0.8 0.012 15.4 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXG52833.1 - 1.4e-05 24.8 2.1 0.078 13.1 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXG52833.1 - 1.7e-05 25.0 0.5 5.4e-05 23.4 0.2 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXG52833.1 - 0.0046 16.9 4.0 2 8.6 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXG52833.1 - 0.015 15.9 1.7 0.73 10.5 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF2201_N PF13203.6 KXG52833.1 - 0.022 14.3 1.7 0.042 13.4 1.7 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain NRBF2_MIT PF17169.4 KXG52833.1 - 0.12 12.6 0.3 0.12 12.6 0.3 1.8 2 0 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 TPR_11 PF13414.6 KXG52833.1 - 0.12 12.1 3.6 0.15 11.8 0.2 2.7 2 1 0 2 2 2 0 TPR repeat Pkinase PF00069.25 KXG52835.1 - 2.3e-13 50.1 0.0 2.9e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG52835.1 - 7.6e-13 48.3 0.0 1.2e-12 47.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase dUTPase PF00692.19 KXG52836.1 - 8.8e-10 38.4 0.0 1.3e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 dUTPase AMP-binding PF00501.28 KXG52837.1 - 2.4e-89 299.9 0.0 3e-89 299.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG52837.1 - 1.2e-11 45.4 0.1 3.4e-11 44.0 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KXG52839.1 - 4.5e-49 167.3 39.3 1.5e-43 149.1 25.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXG52839.1 - 2.4e-07 29.5 3.7 0.0043 15.4 1.2 3.3 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KXG52839.1 - 4.5e-06 25.4 7.0 4.5e-06 25.4 7.0 2.3 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.7 KXG52839.1 - 0.0025 16.7 17.1 0.0064 15.4 7.8 2.9 2 2 0 2 2 2 2 MFS_1 like family LRR19-TM PF15176.6 KXG52839.1 - 0.15 12.1 0.1 0.51 10.3 0.1 1.9 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain ATG22 PF11700.8 KXG52839.1 - 0.18 10.4 11.6 0.064 11.9 0.3 3.3 3 1 0 3 3 3 0 Vacuole effluxer Atg22 like PTR2 PF00854.21 KXG52839.1 - 0.94 8.2 12.4 0.53 9.1 1.0 2.7 2 1 0 2 2 2 0 POT family DUF4491 PF14898.6 KXG52839.1 - 4.6 7.8 7.0 0.58 10.6 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4491) HgmA PF04209.13 KXG52840.1 - 1.9e-167 557.3 0.1 2.4e-167 557.0 0.1 1.1 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase COesterase PF00135.28 KXG52840.1 - 1.5e-53 182.4 0.0 1.9e-51 175.5 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG52840.1 - 0.0019 18.1 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3112 PF11309.8 KXG52841.1 - 1.3e-13 50.9 7.7 4.2e-09 36.2 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3112) ECSCR PF15820.5 KXG52841.1 - 0.028 14.2 0.4 6.7 6.6 0.0 3.0 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator Bac_export_2 PF01312.19 KXG52841.1 - 6.3 5.9 6.5 11 5.1 6.5 1.4 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Metallophos PF00149.28 KXG52842.1 - 5.1e-38 131.6 0.5 8.5e-38 130.9 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXG52842.1 - 0.025 15.0 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain PI31_Prot_N PF11566.8 KXG52843.1 - 1.2e-53 181.2 0.0 1.5e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KXG52843.1 - 3e-17 63.5 17.1 3e-17 63.5 17.1 3.1 3 1 0 3 3 3 1 PI31 proteasome regulator Acyl-CoA_dh_1 PF00441.24 KXG52844.1 - 2.4e-29 102.5 1.6 5.2e-29 101.4 1.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KXG52844.1 - 1.2e-20 73.4 0.0 2.8e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KXG52844.1 - 1.2e-19 70.3 0.2 2.4e-19 69.3 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXG52844.1 - 1.8e-07 31.8 0.3 5.3e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXG52844.1 - 0.0017 18.6 0.0 0.0044 17.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2153 PF09921.9 KXG52844.1 - 0.033 14.0 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) DUF2183 PF09949.9 KXG52845.1 - 5.6e-33 113.2 0.0 1.7e-32 111.7 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.6 KXG52845.1 - 0.014 15.6 0.1 0.044 14.1 0.0 1.8 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain LNS2 PF08235.13 KXG52845.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) UvdE PF03851.14 KXG52846.1 - 1.6e-112 375.3 0.0 2.6e-112 374.6 0.0 1.3 1 0 0 1 1 1 1 UV-endonuclease UvdE PS-DH PF14765.6 KXG52847.1 - 6e-65 219.4 0.0 8.7e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KXG52847.1 - 6.7e-61 206.1 0.1 1.4e-60 205.0 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXG52847.1 - 1.5e-55 187.9 0.1 4e-55 186.5 0.1 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KXG52847.1 - 1.4e-47 162.8 0.6 2.4e-47 162.0 0.6 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXG52847.1 - 1.3e-31 109.0 0.1 4.1e-31 107.4 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXG52847.1 - 4.1e-24 85.2 0.0 9.6e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KXG52847.1 - 6.1e-17 62.2 0.0 3.2e-16 59.9 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KXG52847.1 - 1e-15 57.9 0.0 1.5e-14 54.1 0.0 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG52847.1 - 1.5e-15 58.4 0.0 1.2e-14 55.5 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KXG52847.1 - 2.9e-11 43.5 0.0 8.3e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG52847.1 - 4e-10 40.3 0.8 6.7e-08 33.1 0.0 4.4 6 0 0 6 6 3 1 Methyltransferase domain adh_short PF00106.25 KXG52847.1 - 4.1e-10 39.5 0.1 1.8e-09 37.4 0.1 2.2 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_11 PF08241.12 KXG52847.1 - 8.1e-07 29.6 0.0 7.2e-06 26.6 0.0 2.8 2 0 0 2 2 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KXG52847.1 - 2e-06 27.5 0.0 5.1e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 KXG52847.1 - 6.8e-06 26.0 0.0 2.1e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KXG52847.1 - 0.00022 21.5 0.0 0.00069 19.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.9 KXG52847.1 - 0.002 17.9 0.0 0.0071 16.1 0.0 1.9 2 0 0 2 2 2 1 Lysine methyltransferase ADH_N PF08240.12 KXG52847.1 - 0.0038 17.1 0.1 0.012 15.4 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_24 PF13578.6 KXG52847.1 - 0.1 13.6 0.0 0.61 11.1 0.0 2.5 2 0 0 2 2 1 0 Methyltransferase domain MFS_1 PF07690.16 KXG52848.1 - 1.7e-23 83.1 70.2 1.2e-17 63.9 36.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_membrane PF00664.23 KXG52848.1 - 1.6 8.3 13.9 0.098 12.3 1.4 3.2 2 1 0 2 2 2 0 ABC transporter transmembrane region ADH_zinc_N PF00107.26 KXG52849.1 - 1.8e-18 66.7 0.0 3.7e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG52849.1 - 3.2e-13 50.9 0.0 4.7e-06 27.7 0.0 2.4 1 1 1 2 2 2 2 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG52849.1 - 9.6e-08 31.9 0.1 6.5e-07 29.2 0.1 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KXG52849.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Hexokinase_2 PF03727.16 KXG52852.1 - 1.5e-43 149.0 0.0 1.8e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase DUF1152 PF06626.12 KXG52852.1 - 0.051 12.8 0.0 0.55 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1152) Lipid_DES PF08557.10 KXG52852.1 - 0.41 10.2 1.7 0.55 9.8 0.0 1.9 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) TatD_DNase PF01026.21 KXG52853.1 - 1.9e-45 155.3 0.0 2.1e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Mitofilin PF09731.9 KXG52854.1 - 0.14 10.9 2.7 0.17 10.7 2.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MFS_1 PF07690.16 KXG52855.1 - 3.8e-44 151.0 32.1 1.6e-27 96.4 4.9 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXG52855.1 - 9.1e-11 41.0 20.3 9.2e-08 31.0 2.1 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KXG52855.1 - 0.00039 19.4 16.9 0.012 14.5 0.8 3.5 2 2 1 3 3 3 3 MFS_1 like family LacY_symp PF01306.19 KXG52855.1 - 0.0079 15.0 6.9 0.013 14.3 0.4 2.8 2 2 0 2 2 2 2 LacY proton/sugar symporter OATP PF03137.20 KXG52855.1 - 0.39 9.0 16.6 0.18 10.1 8.0 3.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MARVEL PF01284.23 KXG52856.1 - 0.0053 16.8 11.3 0.27 11.3 13.5 2.0 1 1 1 2 2 2 2 Membrane-associating domain DUF2207 PF09972.9 KXG52856.1 - 0.85 8.3 3.9 2.3 6.9 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SUR7 PF06687.12 KXG52856.1 - 3.8 7.1 12.4 50 3.4 11.7 2.3 1 1 0 1 1 1 0 SUR7/PalI family CENP-S PF15630.6 KXG52857.1 - 2.5e-35 120.7 0.0 3.2e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXG52857.1 - 4e-09 36.6 0.0 4.8e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KXG52857.1 - 8.6e-05 22.5 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated PGA2 PF07543.12 KXG52858.1 - 2.4e-43 147.5 3.4 3.2e-43 147.0 3.4 1.2 1 0 0 1 1 1 1 Protein trafficking PGA2 MMS1_N PF10433.9 KXG52859.1 - 6.5e-133 443.9 0.0 9.4e-133 443.4 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KXG52859.1 - 1.2e-74 251.6 0.1 1.3e-72 244.9 0.0 3.0 4 0 0 4 4 4 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 KXG52859.1 - 0.00027 21.1 0.0 0.074 13.4 0.0 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain SCAN PF02023.17 KXG52859.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 SCAN domain FAD_binding_1 PF00667.20 KXG52860.1 - 1.5e-63 214.4 0.0 2.1e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXG52860.1 - 5e-36 124.0 2.1 9.4e-36 123.2 2.1 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KXG52860.1 - 4.4e-19 69.1 0.0 4.5e-18 65.9 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KXG52860.1 - 0.12 12.6 0.1 0.48 10.7 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain MOR2-PAG1_N PF14222.6 KXG52861.1 - 3.8e-209 696.2 0.0 6.2e-209 695.5 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KXG52861.1 - 1.3e-90 303.7 0.0 5.3e-90 301.7 0.0 2.2 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KXG52861.1 - 1.1e-34 119.4 14.8 5.7e-13 47.5 0.4 4.0 2 1 1 3 3 3 3 Cell morphogenesis central region NAD_binding_2 PF03446.15 KXG52862.1 - 2.6e-32 112.2 0.3 4.3e-32 111.5 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXG52862.1 - 3.4e-29 101.6 0.0 6.4e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KXG52862.1 - 0.00034 21.1 0.0 0.00064 20.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXG52862.1 - 0.011 15.2 0.0 0.023 14.0 0.0 1.8 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TGS PF02824.21 KXG52862.1 - 0.023 14.7 0.0 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 TGS domain Tim17 PF02466.19 KXG52862.1 - 0.047 14.1 0.2 0.099 13.0 0.2 1.6 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family RRM_1 PF00076.22 KXG52863.1 - 4.3e-20 71.3 0.0 1.6e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAPS_reduct PF01507.19 KXG52864.1 - 1e-24 87.5 0.0 5.1e-23 82.0 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family SLS PF14611.6 KXG52864.1 - 0.099 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator MHB PF16525.5 KXG52864.1 - 0.1 12.9 0.1 4.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Haemophore, haem-binding DnaJ PF00226.31 KXG52865.1 - 4.5e-14 52.3 0.6 4.5e-14 52.3 0.6 2.2 3 0 0 3 3 3 1 DnaJ domain HSP20 PF00011.21 KXG52865.1 - 0.013 15.7 1.3 3.9 7.7 1.0 2.9 2 1 0 2 2 2 0 Hsp20/alpha crystallin family FKBP26_C PF18046.1 KXG52865.1 - 0.04 14.0 0.1 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 FKBP26_C-terminal LMBR1 PF04791.16 KXG52865.1 - 2.5 6.9 5.6 2.6 6.9 5.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DEAD PF00270.29 KXG52866.1 - 9.6e-47 159.0 0.0 1.7e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG52866.1 - 9e-24 84.0 0.0 4.6e-23 81.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXG52866.1 - 4.6e-20 71.6 0.0 1.3e-19 70.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXG52866.1 - 5.8e-08 32.9 0.5 1.5e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AA_permease PF00324.21 KXG52867.1 - 2.1e-127 425.6 37.2 2.4e-127 425.4 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG52867.1 - 3.4e-45 154.7 41.8 4.2e-45 154.4 41.8 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 KXG52867.1 - 0.039 14.7 1.0 0.039 14.7 1.0 4.1 4 1 0 5 5 5 0 PrgI family protein Acetyltransf_1 PF00583.25 KXG52868.1 - 1.5e-06 28.4 0.0 2.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXG52868.1 - 0.0038 17.6 0.0 0.0068 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXG52868.1 - 0.0088 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KXG52868.1 - 0.017 15.1 0.1 0.092 12.7 0.0 2.1 1 1 1 2 2 2 0 ESCO1/2 acetyl-transferase p450 PF00067.22 KXG52869.1 - 0.03 13.1 3.0 0.22 10.2 1.6 2.6 2 1 0 2 2 2 0 Cytochrome P450 Spc7 PF08317.11 KXG52870.1 - 0.00039 19.4 10.7 0.00039 19.4 10.7 2.9 2 1 1 3 3 3 1 Spc7 kinetochore protein EzrA PF06160.12 KXG52870.1 - 0.0011 17.3 18.7 0.003 15.8 18.7 1.7 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 KXG52870.1 - 0.0018 18.3 1.2 0.0018 18.3 1.2 3.3 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 KXG52870.1 - 0.018 15.1 6.1 0.018 15.1 6.1 2.9 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus BORCS7 PF16088.5 KXG52870.1 - 0.023 14.9 11.1 1.7 8.9 4.7 3.0 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 7 Relaxase PF03432.14 KXG52870.1 - 0.069 12.7 7.5 0.077 12.6 2.4 2.4 2 0 0 2 2 2 0 Relaxase/Mobilisation nuclease domain Bacillus_HBL PF05791.11 KXG52870.1 - 0.26 11.1 10.2 0.51 10.1 5.9 2.4 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Prefoldin_2 PF01920.20 KXG52870.1 - 0.39 10.7 25.1 3.5 7.6 10.5 3.5 2 1 0 2 2 2 0 Prefoldin subunit BLOC1_2 PF10046.9 KXG52870.1 - 0.49 10.7 18.1 2.1 8.7 3.9 4.2 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.11 KXG52870.1 - 0.73 7.7 7.3 1.4 6.8 7.3 1.5 1 0 0 1 1 1 0 Prominin DUF948 PF06103.11 KXG52870.1 - 0.78 10.0 6.5 2.1 8.7 2.8 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) GIT_CC PF16559.5 KXG52870.1 - 1.1 9.2 9.3 0.1 12.4 2.6 2.8 2 1 1 3 3 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor IL4 PF00727.18 KXG52870.1 - 1.4 9.2 7.9 2.1 8.6 0.2 2.6 2 0 0 2 2 2 0 Interleukin 4 CENP-Q PF13094.6 KXG52870.1 - 1.5 9.0 20.3 0.041 14.1 3.5 2.9 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ATG16 PF08614.11 KXG52870.1 - 1.8 8.8 28.2 1.1 9.5 21.5 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Syntaxin_2 PF14523.6 KXG52870.1 - 1.8 9.0 15.2 0.41 11.0 8.7 2.7 2 0 0 2 2 2 0 Syntaxin-like protein DUF1664 PF07889.12 KXG52870.1 - 2 8.5 18.3 0.16 12.0 3.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SPATA1_C PF15743.5 KXG52870.1 - 2 8.5 18.0 0.22 11.6 12.5 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus Noelin-1 PF12308.8 KXG52870.1 - 2.7 8.0 12.3 0.68 9.9 1.7 4.0 3 1 1 5 5 5 0 Neurogenesis glycoprotein TPR_MLP1_2 PF07926.12 KXG52870.1 - 3.3 7.8 27.2 0.028 14.5 12.6 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3972 PF13118.6 KXG52870.1 - 4 7.9 14.0 5.2 7.5 5.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) Csm1_N PF18504.1 KXG52870.1 - 5.5 7.4 19.9 2.8 8.4 0.4 4.2 2 1 1 3 3 3 0 Csm1 N-terminal domain AAA_13 PF13166.6 KXG52870.1 - 5.8 5.4 20.3 1.1 7.8 16.3 1.7 2 0 0 2 2 2 0 AAA domain DUF4407 PF14362.6 KXG52870.1 - 6.7 6.0 14.6 2.9 7.2 11.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2730 PF10805.8 KXG52870.1 - 7.1 6.8 11.4 6 7.0 2.0 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) Taxilin PF09728.9 KXG52870.1 - 9.7 5.3 28.2 0.46 9.6 22.5 1.6 2 0 0 2 2 2 0 Myosin-like coiled-coil protein AAA_29 PF13555.6 KXG52872.1 - 0.016 14.9 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KXG52872.1 - 0.036 13.4 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KXG52872.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 KXG52872.1 - 0.12 12.7 0.3 1.6 9.0 0.1 2.4 2 1 0 2 2 2 0 AAA domain OTT_1508_deam PF14441.6 KXG52873.1 - 1.4e-19 69.8 1.6 3.5e-19 68.6 1.6 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase GGACT PF06094.12 KXG52874.1 - 5.2e-14 52.9 0.5 6.7e-14 52.5 0.5 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like adh_short PF00106.25 KXG52875.1 - 3.3e-35 121.3 0.0 4.6e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG52875.1 - 5.8e-23 81.7 0.0 7.4e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG52875.1 - 3.4e-05 23.9 0.0 9.4e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXG52875.1 - 0.0001 21.9 0.0 0.00018 21.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXG52875.1 - 0.012 14.7 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF1776 PF08643.10 KXG52875.1 - 0.019 14.4 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KXG52875.1 - 0.03 14.2 0.0 0.044 13.7 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding HET PF06985.11 KXG52876.1 - 6.6e-11 42.8 0.5 1.3e-07 32.0 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 KXG52877.1 - 7.8e-10 38.2 0.2 3.2e-09 36.2 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG52877.1 - 4.4e-08 33.1 6.1 1.2e-07 31.7 6.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N PF02798.20 KXG52878.1 - 5.6e-14 52.2 0.0 9.8e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXG52878.1 - 3.4e-13 49.6 0.0 5.1e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXG52878.1 - 5.1e-13 49.2 0.0 8.9e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXG52878.1 - 3.9e-12 46.2 0.0 5.5e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXG52878.1 - 6.2e-09 36.0 0.0 1.1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXG52878.1 - 0.00024 21.0 0.2 0.00051 20.0 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 KXG52879.1 - 1.3e-21 77.0 43.6 1.3e-21 77.0 43.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG52880.1 - 1.4e-90 304.4 26.5 1.6e-90 304.1 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG52880.1 - 7.2e-15 54.7 58.4 1.4e-13 50.5 32.6 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily YebO PF13974.6 KXG52880.1 - 4.8 7.3 6.7 7.9 6.6 0.0 3.1 3 0 0 3 3 3 0 YebO-like protein Glyco_hydro_3_C PF01915.22 KXG52881.1 - 8.8e-53 179.3 0.0 1.2e-52 178.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXG52881.1 - 1.5e-45 155.9 0.0 2.4e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXG52881.1 - 4.6e-17 61.9 0.1 1e-16 60.8 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KXG52881.1 - 1.4e-16 60.6 0.0 2.8e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Sulfatase PF00884.23 KXG52882.1 - 6.4e-63 213.0 2.5 8.3e-63 212.6 2.5 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXG52882.1 - 4.9e-05 23.1 2.0 0.00025 20.8 2.0 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Phosphoesterase PF04185.14 KXG52882.1 - 0.0067 15.7 0.6 0.063 12.5 0.0 2.2 2 0 0 2 2 2 1 Phosphoesterase family DUF4976 PF16347.5 KXG52882.1 - 0.027 14.7 0.2 0.07 13.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) DUF3285 PF11688.8 KXG52882.1 - 0.033 14.1 0.1 0.069 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) APH PF01636.23 KXG52884.1 - 4.1e-14 53.1 0.0 6.6e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KXG52884.1 - 1.7e-06 27.2 0.2 1.2e-05 24.4 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 KXG52885.1 - 7.2e-07 29.4 0.0 9.3e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HTH_57 PF18679.1 KXG52885.1 - 0.092 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 ThcOx helix turn helix domain ACTH_assoc PF16102.5 KXG52885.1 - 0.13 13.1 0.1 0.33 11.8 0.1 1.8 1 0 0 1 1 1 0 ACTH-associated domain DEAD PF00270.29 KXG52886.1 - 3.2e-47 160.6 0.0 6.7e-47 159.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG52886.1 - 1.7e-23 83.1 0.0 6.1e-23 81.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KXG52886.1 - 8.9e-22 77.1 2.5 2.9e-21 75.5 2.5 2.0 1 0 0 1 1 1 1 DBP10CT (NUC160) domain RPA_C PF08784.11 KXG52887.1 - 4.5e-20 72.3 0.0 1e-19 71.1 0.0 1.6 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KXG52887.1 - 0.00049 20.0 0.2 0.001 19.0 0.2 1.7 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain MatE PF01554.18 KXG52888.1 - 1.4e-56 190.6 27.7 9.4e-34 116.4 10.1 2.3 2 0 0 2 2 2 2 MatE DUF202 PF02656.15 KXG52889.1 - 4e-18 65.6 2.7 1.1e-17 64.2 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3784 PF12650.7 KXG52889.1 - 0.05 13.8 0.8 0.16 12.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF716 PF04819.12 KXG52889.1 - 0.11 12.1 1.1 0.16 11.6 1.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF716) DUF2189 PF09955.9 KXG52889.1 - 0.52 10.6 3.6 0.29 11.4 0.9 1.7 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2189) NUDIX PF00293.28 KXG52890.1 - 3e-26 92.0 0.0 4.4e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain tRNA-synt_2e PF02091.15 KXG52890.1 - 0.046 13.0 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit TauD PF02668.16 KXG52891.1 - 1e-60 205.8 0.3 1.3e-60 205.5 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FMO-like PF00743.19 KXG52892.1 - 3.1e-36 124.9 0.0 1.7e-21 76.3 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXG52892.1 - 3.1e-16 59.5 0.0 1e-15 57.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG52892.1 - 3.6e-14 52.7 0.5 4.1e-10 39.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG52892.1 - 9e-09 35.5 2.1 1.1e-06 28.8 0.6 3.3 3 1 0 3 3 2 1 FAD-NAD(P)-binding DAO PF01266.24 KXG52892.1 - 3.7e-08 33.3 5.1 4.8e-05 23.1 4.5 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXG52892.1 - 1e-07 32.4 1.2 0.00023 21.6 0.5 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG52892.1 - 1.1e-07 32.0 0.1 8.6e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXG52892.1 - 1.4e-07 31.0 0.9 3e-05 23.3 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 KXG52892.1 - 6e-05 22.5 0.2 0.002 17.5 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase ApbA PF02558.16 KXG52892.1 - 0.00019 21.1 0.0 0.026 14.1 0.0 3.0 2 1 1 3 3 3 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KXG52892.1 - 0.0028 17.0 1.8 0.0045 16.3 1.8 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 KXG52892.1 - 0.0054 16.8 1.0 0.068 13.2 0.5 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 KXG52892.1 - 0.0061 16.0 0.0 0.0087 15.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXG52892.1 - 0.016 14.5 1.0 0.05 12.8 0.8 1.8 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KXG52892.1 - 0.029 13.1 2.8 0.05 12.3 2.8 1.3 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 KXG52892.1 - 0.033 14.1 1.5 0.056 13.3 1.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KXG52892.1 - 0.045 13.9 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KXG52892.1 - 0.051 12.9 4.0 0.35 10.1 2.5 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KXG52892.1 - 0.17 11.0 1.0 0.32 10.0 1.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 KXG52892.1 - 0.18 12.2 0.0 5.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 KXG52892.1 - 2.3 7.2 3.2 4 6.4 3.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A zf-C2H2 PF00096.26 KXG52893.1 - 7.1e-09 35.6 11.4 4.4e-05 23.7 2.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXG52893.1 - 2.7e-06 27.7 9.8 0.0061 17.3 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXG52893.1 - 0.0017 18.3 5.7 0.025 14.6 1.6 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KXG52893.1 - 0.0043 17.4 4.8 0.6 10.6 0.3 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KXG52893.1 - 0.013 15.8 3.6 0.021 15.1 3.6 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KXG52893.1 - 0.015 15.7 12.3 1.2 9.7 6.5 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXG52893.1 - 0.016 15.5 5.2 0.058 13.7 1.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KXG52893.1 - 0.12 12.4 6.9 4.9 7.3 4.5 2.4 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.10 KXG52893.1 - 0.42 10.8 4.1 2.9 8.1 0.1 2.3 1 1 1 2 2 2 0 Zinc ribbon domain Ada_Zn_binding PF02805.16 KXG52893.1 - 0.51 10.4 2.9 0.7 10.0 2.0 1.8 2 0 0 2 2 2 0 Metal binding domain of Ada zf-C2H2_2 PF12756.7 KXG52893.1 - 0.85 10.0 8.3 9.7 6.6 0.8 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KXG52893.1 - 3.3 7.6 5.1 10 6.0 0.5 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Pkinase PF00069.25 KXG52895.1 - 1e-22 80.8 0.0 1.6e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 KXG52895.1 - 5.7e-09 35.5 4.3 0.6 10.5 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat WD40 PF00400.32 KXG52895.1 - 5.1e-06 27.1 15.4 7.3e-06 26.6 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 KXG52895.1 - 2.3e-05 23.8 0.0 5.7e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 KXG52895.1 - 0.00013 22.3 2.0 10 6.6 0.4 4.3 4 1 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KXG52895.1 - 0.0072 16.8 0.3 2.7 8.6 0.1 3.6 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.7 KXG52895.1 - 0.016 15.2 0.0 0.17 12.0 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 KXG52895.1 - 0.019 14.5 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 Tti2 family Ge1_WD40 PF16529.5 KXG52895.1 - 0.13 11.2 1.2 0.33 9.8 0.0 2.2 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DENN PF02141.21 KXG52896.1 - 3.6e-40 137.9 0.1 6.7e-40 137.0 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KXG52896.1 - 1.4e-05 25.7 0.1 8.5e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 uDENN domain PqqD PF05402.12 KXG52896.1 - 0.054 13.8 0.4 1.5 9.2 0.0 2.9 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) AAT PF03417.16 KXG52896.1 - 0.12 12.0 1.3 9 5.9 0.1 3.0 2 1 1 3 3 3 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Cnn_1N PF07989.11 KXG52896.1 - 0.39 10.9 11.9 0.14 12.3 3.1 3.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Elongin_A PF06881.11 KXG52896.1 - 0.68 10.5 11.5 0.021 15.3 4.5 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A CENP-F_leu_zip PF10473.9 KXG52896.1 - 0.78 9.8 20.2 0.071 13.1 7.6 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 KXG52896.1 - 2.4 8.3 17.1 4.1 7.5 7.5 3.5 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase DUF3450 PF11932.8 KXG52896.1 - 5.2 6.3 16.0 4.5 6.5 4.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) adh_short_C2 PF13561.6 KXG52897.1 - 1.6e-54 185.0 1.9 1.9e-54 184.7 1.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG52897.1 - 3.3e-45 153.9 0.9 4.2e-45 153.6 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG52897.1 - 3.3e-09 36.9 0.4 9.6e-09 35.4 0.4 1.6 1 1 0 1 1 1 1 KR domain RabGAP-TBC PF00566.18 KXG52898.1 - 9.3e-43 146.4 0.0 1.5e-40 139.2 0.0 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Fungal_trans PF04082.18 KXG52901.1 - 2e-07 30.3 0.0 3.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FOXP-CC PF16159.5 KXG52902.1 - 0.2 12.3 3.0 9.4 7.0 0.2 2.6 1 1 1 2 2 2 0 FOXP coiled-coil domain Ribosomal_L26 PF16906.5 KXG52903.1 - 5.7e-36 122.8 1.6 7e-36 122.6 1.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KXG52903.1 - 2.3e-05 24.2 0.3 5.8e-05 22.9 0.3 1.7 1 0 0 1 1 1 1 KOW motif Synaptobrevin PF00957.21 KXG52904.1 - 1.1e-31 108.4 0.0 1.5e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KXG52904.1 - 3e-27 94.5 0.0 4.8e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sporozoite_P67 PF05642.11 KXG52906.1 - 0.02 13.0 1.3 0.025 12.7 1.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.13 KXG52906.1 - 0.27 11.1 3.5 0.45 10.4 3.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.11 KXG52906.1 - 0.48 10.4 3.8 0.86 9.6 3.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 KXG52906.1 - 0.92 9.2 13.0 1.4 8.6 13.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 KXG52906.1 - 1.5 7.0 6.1 2 6.6 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 KXG52906.1 - 2 8.1 5.5 3.6 7.2 5.5 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 KXG52906.1 - 2.9 7.1 13.5 4.1 6.6 13.5 1.1 1 0 0 1 1 1 0 NOA36 protein Acetyltransf_10 PF13673.7 KXG52907.1 - 2.2e-10 40.5 0.0 3.1e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXG52907.1 - 3.2e-10 40.3 0.0 4.3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG52907.1 - 1.7e-09 37.9 0.0 2.1e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KXG52907.1 - 8.9e-06 25.6 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KXG52907.1 - 0.00038 20.5 0.0 0.00067 19.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.6 KXG52907.1 - 0.07 12.5 0.0 0.091 12.2 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 GNAT_acetyltran PF12746.7 KXG52907.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_15 PF17013.5 KXG52907.1 - 0.21 11.0 0.0 0.37 10.2 0.0 1.3 1 1 0 1 1 1 0 Putative acetyl-transferase Ion_trans PF00520.31 KXG52908.1 - 6.5e-07 28.8 27.8 1.6e-06 27.6 27.8 1.6 1 1 0 1 1 1 1 Ion transport protein CPSase_L_D2 PF02786.17 KXG52909.1 - 9.5e-115 381.4 0.2 3.5e-84 281.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 KXG52909.1 - 3.2e-47 160.7 0.0 2.7e-46 157.8 0.0 2.4 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KXG52909.1 - 1.4e-46 157.5 0.0 3.3e-46 156.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 KXG52909.1 - 3.7e-46 156.8 0.1 8.2e-46 155.7 0.1 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KXG52909.1 - 7.6e-37 126.4 0.0 1.8e-36 125.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KXG52909.1 - 2.8e-29 102.2 0.0 7.4e-29 100.9 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KXG52909.1 - 4.7e-20 71.6 0.0 1.9e-19 69.7 0.0 2.2 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KXG52909.1 - 2.9e-18 66.1 0.8 1.4e-08 34.5 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXG52909.1 - 7.8e-15 54.9 0.1 9.3e-08 31.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KXG52909.1 - 1.7e-09 37.5 0.0 0.00024 20.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KXG52909.1 - 7e-06 26.0 0.1 0.00044 20.1 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 KXG52909.1 - 0.00016 21.7 3.3 0.37 10.8 0.1 3.4 4 0 0 4 4 4 2 ATP-grasp domain RimK PF08443.11 KXG52909.1 - 0.0017 18.0 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain DJ-1_PfpI PF01965.24 KXG52909.1 - 0.0027 17.5 0.8 0.73 9.6 0.0 4.1 4 0 0 4 4 4 1 DJ-1/PfpI family MFS_1 PF07690.16 KXG52910.1 - 4.9e-22 78.3 12.7 4.9e-22 78.3 12.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG52910.1 - 3.6e-06 26.1 9.6 9.7e-06 24.7 9.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter NrsF PF06532.11 KXG52910.1 - 0.11 12.2 0.2 0.11 12.2 0.2 3.2 2 1 1 3 3 3 0 Negative regulator of sigma F AMP-binding PF00501.28 KXG52911.1 - 7e-77 258.8 0.0 8.4e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG52911.1 - 8.1e-11 42.7 0.5 2.5e-10 41.2 0.6 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Exo84_C PF16528.5 KXG52912.1 - 3e-67 226.4 1.7 4.9e-67 225.7 0.1 1.9 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KXG52912.1 - 2.7e-15 56.2 3.3 2.7e-15 56.2 3.3 1.8 2 0 0 2 2 2 1 Vps51/Vps67 APG6_N PF17675.1 KXG52912.1 - 0.079 13.5 5.7 2.1 8.9 3.1 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF2594 PF10769.9 KXG52912.1 - 0.09 12.8 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2594) DUF4088 PF13317.6 KXG52912.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) SKA2 PF16740.5 KXG52912.1 - 0.43 10.4 3.2 0.48 10.2 1.0 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 HIP1_clath_bdg PF16515.5 KXG52912.1 - 2.2 9.0 6.8 0.61 10.7 2.6 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BST2 PF16716.5 KXG52912.1 - 3.6 8.2 6.9 15 6.3 3.2 2.7 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 MAS20 PF02064.15 KXG52913.1 - 2.1e-43 147.5 0.2 2.4e-43 147.3 0.2 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor Glyco_hydro_72 PF03198.14 KXG52914.1 - 8.6e-126 419.4 1.1 1.1e-125 419.1 1.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KXG52914.1 - 6.3e-06 25.8 0.0 0.00054 19.5 0.0 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KXG52914.1 - 0.058 12.5 0.2 0.23 10.6 0.2 1.9 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain AMP-binding PF00501.28 KXG52915.1 - 8.6e-93 311.2 0.0 1e-92 311.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG52915.1 - 2.8e-16 60.3 0.7 6.1e-16 59.2 0.7 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain F-box-like PF12937.7 KXG52916.1 - 1.2e-08 34.7 0.1 2.6e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXG52916.1 - 5.2e-07 29.4 0.3 1.4e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KXG52916.1 - 0.015 15.2 0.0 0.053 13.4 0.0 1.9 2 0 0 2 2 2 0 F-box Hira PF07569.11 KXG52916.1 - 0.18 11.5 0.0 0.44 10.2 0.0 1.6 1 0 0 1 1 1 0 TUP1-like enhancer of split UIM PF02809.20 KXG52916.1 - 1.5 9.0 11.8 2.5 8.2 0.3 3.6 3 0 0 3 3 3 0 Ubiquitin interaction motif AtuA PF07287.11 KXG52917.1 - 2.5e-123 411.3 0.0 3.9e-123 410.6 0.0 1.2 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Mre11_DNA_bind PF04152.14 KXG52917.1 - 3.2e-56 190.3 1.5 3.2e-56 190.3 1.5 2.0 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KXG52917.1 - 6e-14 53.0 1.0 1.4e-13 51.8 1.0 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXG52917.1 - 0.0049 17.1 0.0 0.029 14.6 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aldedh PF00171.22 KXG52918.1 - 3.2e-184 612.8 0.6 3.6e-184 612.6 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAD_binding_3 PF01494.19 KXG52919.1 - 2.8e-15 56.5 0.5 5.4e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXG52919.1 - 1.6e-08 34.6 1.0 4.8e-08 33.1 1.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXG52919.1 - 3.3e-07 30.2 1.1 5.4e-07 29.5 1.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXG52919.1 - 2.7e-06 26.7 0.1 3.6e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KXG52919.1 - 1.5e-05 24.6 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG52919.1 - 2.8e-05 23.5 2.4 7.8e-05 22.0 2.5 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG52919.1 - 7.4e-05 22.0 4.7 0.0002 20.6 4.5 1.7 1 1 1 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 KXG52919.1 - 0.00017 21.0 0.2 0.0031 16.9 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.22 KXG52919.1 - 0.00048 19.3 1.2 0.00093 18.4 1.2 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KXG52919.1 - 0.003 16.5 3.0 0.21 10.4 1.8 2.3 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 KXG52919.1 - 0.013 16.1 1.1 0.034 14.7 1.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXG52919.1 - 0.015 14.0 1.9 0.022 13.5 1.9 1.2 1 0 0 1 1 1 0 HI0933-like protein Rossmann-like PF10727.9 KXG52919.1 - 0.022 14.6 0.6 0.048 13.5 0.6 1.5 1 0 0 1 1 1 0 Rossmann-like domain AlaDh_PNT_C PF01262.21 KXG52919.1 - 0.037 13.3 1.1 0.064 12.5 1.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KXG52919.1 - 0.15 11.3 1.0 0.34 10.1 1.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KXG52919.1 - 0.22 10.3 0.3 0.36 9.6 0.3 1.3 1 0 0 1 1 1 0 MCRA family 3HCDH_N PF02737.18 KXG52919.1 - 6.5 6.6 5.5 1 9.2 1.7 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_32N PF00251.20 KXG52920.1 - 1.7e-95 320.2 5.1 2.2e-95 319.8 5.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KXG52920.1 - 3.3e-33 114.9 1.2 6.2e-33 114.0 1.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.6 KXG52920.1 - 0.04 13.2 0.4 0.25 10.6 0.4 2.0 1 1 0 1 1 1 0 BNR repeat-like domain DUF4975 PF16346.5 KXG52920.1 - 0.05 13.7 0.3 0.17 11.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4975) CHB_HEX_C PF03174.13 KXG52920.1 - 0.097 12.7 0.2 0.45 10.5 0.1 2.2 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain Sugar_tr PF00083.24 KXG52921.1 - 1.7e-127 426.1 20.1 1.9e-127 425.9 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG52921.1 - 3.1e-23 82.3 24.8 3.1e-23 82.3 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GDP_Man_Dehyd PF16363.5 KXG52921.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_hydro_32N PF00251.20 KXG52922.1 - 1.7e-43 149.4 0.9 2.5e-42 145.5 0.9 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KXG52922.1 - 8.1e-31 107.1 0.0 1.3e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 KXG52922.1 - 0.0023 18.0 0.1 0.0073 16.4 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4975) BNR PF02012.20 KXG52922.1 - 0.01 15.7 0.2 0.061 13.3 0.2 2.5 1 0 0 1 1 1 0 BNR/Asp-box repeat CHB_HEX_C PF03174.13 KXG52922.1 - 0.04 13.9 0.6 0.52 10.3 0.0 2.8 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain Fungal_trans PF04082.18 KXG52924.1 - 0.00092 18.3 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Smg4_UPF3 PF03467.15 KXG52925.1 - 1.4e-43 148.9 0.0 1.4e-43 148.9 0.0 2.5 2 1 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.22 KXG52925.1 - 1.5e-08 34.3 0.0 5.5e-07 29.3 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M19 PF01244.21 KXG52926.1 - 6.8e-101 337.6 0.0 8.1e-101 337.4 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Peptidase_M35 PF02102.15 KXG52927.1 - 4.4e-178 591.6 13.9 5e-178 591.5 13.9 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KXG52927.1 - 9.1e-41 139.8 4.9 1.5e-40 139.1 4.9 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HMGL-like PF00682.19 KXG52927.1 - 0.0017 18.0 0.2 0.0028 17.2 0.1 1.5 2 0 0 2 2 2 1 HMGL-like CARDB PF07705.11 KXG52927.1 - 0.047 13.9 0.8 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 CARDB Sua5_yciO_yrdC PF01300.18 KXG52928.1 - 5.1e-11 42.4 0.0 1.3e-10 41.0 0.0 1.7 2 1 0 2 2 2 1 Telomere recombination HalOD1 PF18545.1 KXG52928.1 - 0.008 16.4 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Halobacterial output domain 1 Peptidase_A4 PF01828.17 KXG52929.1 - 5.7e-74 248.1 5.6 7.2e-74 247.8 5.6 1.1 1 0 0 1 1 1 1 Peptidase A4 family Fungal_trans_2 PF11951.8 KXG52930.1 - 1.9e-13 50.0 2.4 7.3e-08 31.6 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Birna_RdRp PF04197.12 KXG52930.1 - 0.24 9.7 0.0 0.32 9.3 0.0 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Abhydrolase_6 PF12697.7 KXG52931.1 - 2.5e-10 41.4 0.3 2.5e-10 41.4 0.3 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG52931.1 - 6.1e-09 35.9 0.0 3.4e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG52931.1 - 5.9e-07 29.0 0.0 1.8e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXG52931.1 - 4.1e-05 22.4 0.0 6.1e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 KXG52931.1 - 0.054 13.1 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_4 PF08386.10 KXG52931.1 - 0.063 13.4 0.1 0.55 10.4 0.0 2.5 3 0 0 3 3 3 0 TAP-like protein Lactonase PF10282.9 KXG52932.1 - 2.6e-20 73.0 0.0 3.4e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller CMD PF02627.20 KXG52933.1 - 1.2e-07 31.7 0.0 1.4e-06 28.2 0.0 2.2 2 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family Cellulase PF00150.18 KXG52934.1 - 1.9e-51 175.2 0.1 2.5e-51 174.8 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KXG52934.1 - 3.2e-13 49.4 10.9 3.2e-13 49.4 10.9 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain DUF3439 PF11921.8 KXG52934.1 - 2.4 8.1 10.5 6.4 6.8 10.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_hydro_7 PF00840.20 KXG52935.1 - 2.8e-214 711.8 13.9 2.8e-214 711.8 13.9 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KXG52935.1 - 7.4e-12 45.0 11.7 7.4e-12 45.0 11.7 4.0 4 0 0 4 4 4 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KXG52935.1 - 0.12 12.7 2.8 0.56 10.5 2.8 2.2 1 0 0 1 1 1 0 Toxin 7 Formyl_trans_N PF00551.19 KXG52936.1 - 7.5e-40 136.6 0.2 9.5e-40 136.3 0.2 1.1 1 0 0 1 1 1 1 Formyl transferase ACT_6 PF13740.6 KXG52936.1 - 1.7e-07 31.1 0.1 9.4e-07 28.7 0.0 2.4 2 1 0 2 2 2 1 ACT domain ACT PF01842.25 KXG52936.1 - 5e-07 29.4 0.1 3.1e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 ACT domain NUDIX PF00293.28 KXG52937.1 - 2.4e-08 34.1 0.0 3.6e-08 33.5 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain Methyltransf_23 PF13489.6 KXG52938.1 - 3e-11 43.5 0.0 4.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG52938.1 - 2.5e-07 31.3 0.0 7.4e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG52938.1 - 0.00015 21.6 0.0 0.0013 18.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG52938.1 - 0.00037 21.2 0.0 0.0048 17.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG52938.1 - 0.00084 19.9 0.0 0.002 18.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KXG52938.1 - 0.0066 16.0 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 KXG52938.1 - 0.0068 15.9 0.0 0.018 14.5 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KXG52938.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Aconitase PF00330.20 KXG52939.1 - 2.3e-34 119.2 0.0 1e-32 113.8 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXG52939.1 - 0.17 12.2 0.0 0.46 10.8 0.0 1.8 1 0 0 1 1 1 0 Aconitase C-terminal domain CutC PF03932.14 KXG52940.1 - 3.3e-46 157.4 0.0 5.6e-46 156.6 0.0 1.4 1 1 0 1 1 1 1 CutC family BppL_N PF18338.1 KXG52940.1 - 0.1 12.4 0.4 0.21 11.4 0.4 1.5 1 0 0 1 1 1 0 Lower baseplate protein N-terminal domain VASP_tetra PF08776.11 KXG52940.1 - 0.21 11.2 1.2 1.4 8.5 0.2 2.3 2 0 0 2 2 2 0 VASP tetramerisation domain DUF1485 PF07364.12 KXG52941.1 - 2.1e-104 348.9 0.9 2.6e-104 348.5 0.9 1.1 1 0 0 1 1 1 1 Metallopeptidase family M81 MlrC_C PF07171.12 KXG52941.1 - 1.3e-57 194.8 0.1 2e-57 194.3 0.1 1.3 1 0 0 1 1 1 1 MlrC C-terminus Ribonuc_L-PSP PF01042.21 KXG52942.1 - 1.9e-10 40.8 0.0 2.7e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Abhydrolase_1 PF00561.20 KXG52944.1 - 2.1e-13 50.5 0.4 2.9e-13 50.0 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG52944.1 - 9.8e-13 49.2 6.2 1.4e-12 48.7 6.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG52944.1 - 1.4e-06 27.8 0.0 2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KXG52944.1 - 0.00055 20.1 0.0 0.00077 19.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KXG52944.1 - 0.063 12.9 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase APH PF01636.23 KXG52946.1 - 0.0017 18.3 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXG52946.1 - 0.065 12.2 0.3 0.47 9.3 0.0 2.0 1 1 1 2 2 2 0 Haspin like kinase domain NMT_C PF02799.15 KXG52949.1 - 3.6e-65 219.4 0.0 4.8e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KXG52949.1 - 9.6e-65 217.3 0.0 2e-64 216.2 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KXG52949.1 - 0.0023 18.0 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cwf_Cwc_15 PF04889.12 KXG52951.1 - 0.0027 17.5 11.6 0.004 16.9 11.6 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein POX PF07526.11 KXG52951.1 - 0.0055 17.3 1.1 0.011 16.4 1.1 1.4 1 0 0 1 1 1 1 Associated with HOX HJURP_C PF12347.8 KXG52951.1 - 0.1 12.7 1.9 0.28 11.2 0.1 2.5 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat DUF334 PF03904.13 KXG52951.1 - 0.45 10.0 3.1 0.63 9.5 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) SPG4 PF17325.2 KXG52951.1 - 0.75 10.9 6.3 5.2 8.2 5.6 2.5 2 1 0 2 2 2 0 Stationary phase protein 4 OTT_1508_deam PF14441.6 KXG52952.1 - 7.8e-16 57.8 0.3 2e-15 56.6 0.3 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase HMG_box PF00505.19 KXG52955.1 - 5.5e-13 49.1 0.1 1e-12 48.3 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXG52955.1 - 0.0039 17.7 0.4 0.01 16.4 0.0 1.9 2 0 0 2 2 2 1 HMG-box domain MATalpha_HMGbox PF04769.12 KXG52955.1 - 0.035 13.4 0.1 0.052 12.8 0.1 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box DUF4698 PF15769.5 KXG52956.1 - 0.075 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) DUF2267 PF10025.9 KXG52957.1 - 0.046 14.0 0.0 0.084 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) LRAT PF04970.13 KXG52958.1 - 0.019 15.3 0.0 0.022 15.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase AAA PF00004.29 KXG52959.1 - 3.8e-19 69.4 0.1 1.3e-17 64.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXG52959.1 - 0.00053 20.4 1.8 0.097 13.1 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain FANCI_HD2 PF14680.6 KXG52959.1 - 0.0027 17.0 0.7 0.0068 15.7 0.7 1.7 1 0 0 1 1 1 1 FANCI helical domain 2 AAA_17 PF13207.6 KXG52959.1 - 0.0062 17.0 0.0 0.089 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXG52959.1 - 0.0091 16.3 2.9 5.6 7.2 0.0 3.4 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.14 KXG52959.1 - 0.023 14.7 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXG52959.1 - 0.028 15.0 0.0 0.094 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 KXG52959.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DASH_Dad1 PF08649.10 KXG52959.1 - 0.37 11.0 1.3 7 6.9 0.1 3.4 3 0 0 3 3 3 0 DASH complex subunit Dad1 Pkinase PF00069.25 KXG52961.1 - 4.3e-19 68.9 0.0 1e-18 67.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG52961.1 - 5.1e-14 52.2 0.0 1e-13 51.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXG52961.1 - 0.00043 19.7 0.1 0.00073 18.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-bind_6 PF13921.6 KXG52962.1 - 0.0069 16.6 1.2 0.035 14.3 0.7 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Glyco_hydro_16 PF00722.21 KXG52963.1 - 1.7e-07 30.9 0.4 7.2e-07 28.9 0.0 2.1 3 0 0 3 3 3 1 Glycosyl hydrolases family 16 Glyco_hydro_20 PF00728.22 KXG52964.1 - 1.4e-81 274.7 0.0 1.7e-81 274.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KXG52964.1 - 4.9e-31 108.2 0.1 9e-31 107.4 0.1 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KXG52964.1 - 5.5e-07 30.4 0.3 2.6e-05 25.0 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Pkinase PF00069.25 KXG52965.1 - 9e-55 185.9 0.0 1.4e-53 182.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG52965.1 - 6.1e-25 88.0 0.5 1.6e-19 70.2 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KXG52965.1 - 3.2e-06 26.3 0.0 4.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXG52965.1 - 0.00032 20.1 0.0 0.00068 19.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXG52965.1 - 0.00051 19.4 0.3 0.0012 18.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXG52965.1 - 0.0045 16.9 6.6 0.012 15.6 0.1 3.0 2 2 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KXG52965.1 - 0.0055 15.8 0.1 0.013 14.6 0.0 1.5 2 0 0 2 2 2 1 Seadornavirus VP7 NFACT-C PF11923.8 KXG52965.1 - 0.014 15.3 0.2 0.034 14.0 0.2 1.6 1 0 0 1 1 1 0 NFACT protein C-terminal domain Pkinase_fungal PF17667.1 KXG52965.1 - 0.064 12.0 0.2 0.14 10.9 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Spt20 PF12090.8 KXG52965.1 - 6.7 6.3 14.0 11 5.5 14.0 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 KXG52965.1 - 8.2 6.3 19.8 20 5.0 19.8 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SF3A2 PF16835.5 KXG52966.1 - 1.5e-36 124.6 0.1 2.4e-36 124.0 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KXG52966.1 - 9.6e-06 25.8 0.5 2e-05 24.8 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.11 KXG52966.1 - 0.045 13.3 1.5 0.11 12.1 1.5 1.7 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CAP_GLY PF01302.25 KXG52967.1 - 3.1e-18 65.5 0.2 5.1e-18 64.9 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KXG52967.1 - 6.8e-16 58.1 9.3 0.00025 21.4 0.5 4.8 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXG52967.1 - 3.2e-10 39.6 10.1 6.2e-05 22.7 2.0 5.0 2 2 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 KXG52967.1 - 3.5e-08 32.9 6.1 0.26 11.4 0.0 6.1 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.6 KXG52967.1 - 6.3e-07 29.1 0.9 0.064 12.8 0.2 3.7 1 1 3 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.33 KXG52967.1 - 0.0019 18.5 5.7 22 6.1 0.0 5.8 6 0 0 6 6 6 1 Leucine Rich Repeat Zn_clus PF00172.18 KXG52968.1 - 7.6e-08 32.4 8.8 7.6e-08 32.4 8.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-U1 PF06220.12 KXG52969.1 - 9e-06 25.4 0.1 1.6e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 U1 zinc finger ATP_bind_1 PF03029.17 KXG52970.1 - 7.4e-73 245.3 0.0 1.2e-72 244.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KXG52970.1 - 1.3e-05 24.8 0.0 0.0013 18.4 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KXG52970.1 - 0.00029 19.9 0.0 0.13 11.2 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KXG52970.1 - 0.00053 20.1 0.0 0.0044 17.1 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KXG52970.1 - 0.0019 17.7 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 KXG52970.1 - 0.0023 17.7 0.0 0.0057 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 KXG52970.1 - 0.0023 17.7 0.1 0.014 15.2 0.0 2.2 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 KXG52970.1 - 0.0028 17.3 0.0 0.023 14.3 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KXG52970.1 - 0.004 17.6 0.0 0.0092 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KXG52970.1 - 0.0044 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXG52970.1 - 0.0048 17.2 0.0 0.016 15.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 KXG52970.1 - 0.0053 16.0 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 KXG52970.1 - 0.0054 16.9 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 KXG52970.1 - 0.0069 15.6 0.0 0.2 10.8 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 KXG52970.1 - 0.007 15.9 0.0 0.23 11.0 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B cobW PF02492.19 KXG52970.1 - 0.011 15.4 0.0 1 8.9 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 KXG52970.1 - 0.015 14.8 0.0 6.2 6.2 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_30 PF13604.6 KXG52970.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KXG52970.1 - 0.017 15.3 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Methyltransf_32 PF13679.6 KXG52970.1 - 0.018 15.1 0.1 0.036 14.0 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain RsgA_GTPase PF03193.16 KXG52970.1 - 0.032 14.1 0.0 9.7 6.1 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase CLP1_P PF16575.5 KXG52970.1 - 0.037 13.8 0.0 0.31 10.8 0.0 2.2 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PduV-EutP PF10662.9 KXG52970.1 - 0.11 12.2 0.1 0.88 9.3 0.0 2.4 3 1 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation DUF4461 PF14688.6 KXG52970.1 - 0.16 11.7 0.2 0.26 11.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) GST_N_3 PF13417.6 KXG52972.1 - 1.6e-20 73.2 0.0 3.5e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXG52972.1 - 1.3e-17 63.8 0.0 2.7e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXG52972.1 - 6.7e-09 36.0 0.0 1.3e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXG52972.1 - 5.2e-07 29.6 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXG52972.1 - 0.00018 22.1 0.0 0.00031 21.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXG52972.1 - 0.0041 17.3 0.0 0.012 15.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXG52972.1 - 0.02 15.1 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KXG52972.1 - 0.027 14.7 0.1 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin SUZ PF12752.7 KXG52973.1 - 1.6e-05 25.5 2.3 1.6e-05 25.5 2.3 4.3 2 1 1 3 3 3 1 SUZ domain NARP1 PF12569.8 KXG52973.1 - 0.00014 20.9 1.2 0.00017 20.7 0.3 1.5 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 Aldo_ket_red PF00248.21 KXG52976.1 - 9.1e-53 179.3 0.0 2.6e-52 177.9 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.6 KXG52977.1 - 1.7e-21 76.2 0.0 2.9e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXG52977.1 - 1e-20 73.5 0.0 2.6e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KXG52977.1 - 0.00041 20.7 0.0 0.28 11.4 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Apt1 PF10351.9 KXG52977.1 - 0.0064 15.4 0.2 0.031 13.2 0.0 1.8 2 0 0 2 2 2 1 Golgi-body localisation protein domain HAD_2 PF13419.6 KXG52977.1 - 0.027 14.5 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KXG52977.1 - 0.039 13.6 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase LRR_4 PF12799.7 KXG52978.1 - 2.5e-05 24.5 1.6 1.3 9.5 0.0 5.1 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KXG52978.1 - 0.0085 16.0 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KXG52978.1 - 0.12 12.5 8.4 0.51 10.5 0.2 4.5 5 0 0 5 5 5 0 Leucine Rich repeat Hemopexin PF00045.19 KXG52979.1 - 2.2e-13 49.9 0.1 0.0072 16.3 0.0 4.6 4 1 0 4 4 4 3 Hemopexin MAAL_N PF05034.13 KXG52979.1 - 0.00083 19.0 0.0 0.19 11.3 0.0 2.1 1 1 1 2 2 2 2 Methylaspartate ammonia-lyase N-terminus TnpB_IS66 PF05717.13 KXG52979.1 - 0.18 11.7 0.0 5.6 7.0 0.0 2.7 3 0 0 3 3 3 0 IS66 Orf2 like protein BSD PF03909.17 KXG52980.1 - 2.6e-27 94.6 8.6 2.1e-14 53.3 0.8 3.0 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 KXG52980.1 - 1.8e-24 85.9 0.0 3.9e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain PIN_8 PF18476.1 KXG52980.1 - 0.052 13.4 0.3 0.052 13.4 0.3 1.8 2 0 0 2 2 2 0 PIN like domain Sulfotransfer_1 PF00685.27 KXG52980.1 - 0.13 11.8 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Sulfotransferase domain CysG_dimeriser PF10414.9 KXG52980.1 - 1.2 8.9 5.0 4.4 7.1 0.4 3.7 3 1 0 3 3 3 0 Sirohaem synthase dimerisation region ING PF12998.7 KXG52982.1 - 7.4e-12 45.7 0.0 1.7e-11 44.6 0.0 1.7 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KXG52982.1 - 1.6e-06 27.9 7.7 2.7e-06 27.2 7.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KXG52982.1 - 0.073 13.3 1.0 0.16 12.2 1.0 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KXG52982.1 - 0.3 10.7 2.8 0.58 9.8 2.8 1.4 1 0 0 1 1 1 0 PHD-finger Prp19 PF08606.11 KXG52982.1 - 2.9 8.0 6.3 9.9 6.2 2.4 2.4 2 0 0 2 2 2 0 Prp19/Pso4-like Transket_pyr PF02779.24 KXG52983.1 - 1.1e-65 220.6 0.0 2e-65 219.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KXG52983.1 - 2.9e-59 200.5 0.0 4.3e-59 199.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KXG52983.1 - 6.9e-57 191.4 0.0 1.2e-56 190.6 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KXG52983.1 - 2.8e-18 65.2 0.7 2.8e-18 65.2 0.7 1.9 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus DJ-1_PfpI PF01965.24 KXG52986.1 - 2.4e-11 43.7 0.0 2.8e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Sld5 PF05916.11 KXG52987.1 - 1.3e-19 70.7 0.0 3.4e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 GINS complex protein Cnn_1N PF07989.11 KXG52987.1 - 7.7e-07 29.2 7.7 7.7e-07 29.2 7.7 2.1 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 YabA PF06156.13 KXG52987.1 - 0.031 14.9 2.0 3.1 8.5 4.4 2.6 2 0 0 2 2 2 0 Initiation control protein YabA zf-C2H2 PF00096.26 KXG52988.1 - 0.0017 18.7 4.2 0.005 17.2 4.2 1.8 1 1 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KXG52988.1 - 0.027 14.2 10.9 0.047 13.5 1.7 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.15 KXG52988.1 - 0.048 13.7 1.9 0.054 13.5 0.1 2.0 2 0 0 2 2 2 0 BED zinc finger zf-CHCC PF10276.9 KXG52988.1 - 0.056 13.5 6.5 0.11 12.6 2.7 2.6 3 0 0 3 3 3 0 Zinc-finger domain zf-Di19 PF05605.12 KXG52988.1 - 0.076 13.3 1.6 0.18 12.1 1.6 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_10 PF10058.9 KXG52988.1 - 0.28 10.9 2.0 0.74 9.6 2.0 1.7 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-H2C2_2 PF13465.6 KXG52988.1 - 0.95 10.0 5.9 10 6.8 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXG52988.1 - 2.2 9.3 4.7 18 6.5 4.7 2.3 1 1 0 1 1 1 0 C2H2-type zinc finger TF_Zn_Ribbon PF08271.12 KXG52989.1 - 0.11 12.0 0.4 12 5.5 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Sod_Fe_C PF02777.18 KXG52990.1 - 1.8e-35 121.2 1.5 2.1e-35 121.0 0.2 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KXG52990.1 - 5.5e-29 100.5 2.6 9.5e-29 99.7 2.6 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GCFC PF07842.12 KXG52991.1 - 3.4e-83 279.5 3.2 6e-83 278.6 3.2 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KXG52991.1 - 5.8e-18 64.5 1.0 1.3e-17 63.4 1.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXG52991.1 - 1.2e-08 34.9 0.8 1.2e-08 34.9 0.8 2.1 2 1 0 2 2 2 1 G-patch domain IHABP4_N PF16174.5 KXG52991.1 - 0.019 15.6 9.8 0.049 14.2 9.8 1.7 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal HSBP1 PF06825.12 KXG52991.1 - 0.1 12.5 0.3 0.42 10.5 0.5 1.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 VIT1 PF01988.19 KXG52992.1 - 6.9e-63 212.4 7.3 8.3e-63 212.1 7.3 1.1 1 0 0 1 1 1 1 VIT family DUF3947 PF13135.6 KXG52992.1 - 0.096 12.9 0.6 0.21 11.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) SLATT_fungal PF18142.1 KXG52992.1 - 0.16 11.9 0.5 0.34 10.9 0.5 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain DUF4202 PF13875.6 KXG52993.1 - 3.5e-79 265.0 0.7 3.9e-79 264.9 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) PilM_2 PF11104.8 KXG52993.1 - 0.084 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; PAM2 PF07145.15 KXG52993.1 - 0.14 11.9 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Sugar_tr PF00083.24 KXG52994.1 - 7.6e-81 272.3 24.9 9.4e-81 272.0 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG52994.1 - 3e-22 79.0 27.7 3e-22 79.0 27.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5345 PF17280.2 KXG52994.1 - 0.0028 17.6 1.7 0.51 10.3 0.4 2.9 2 0 0 2 2 2 2 Family of unknown function (DUF5345) Caps_synth PF05704.12 KXG52994.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Cation_efflux PF01545.21 KXG52995.1 - 1.2e-26 93.7 8.7 1.4e-26 93.4 8.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXG52995.1 - 6.1e-11 42.3 0.2 1.1e-10 41.5 0.2 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF423 PF04241.15 KXG52995.1 - 0.55 10.5 4.6 11 6.3 0.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF423) p450 PF00067.22 KXG52996.1 - 1.6e-52 178.8 0.0 1.9e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rox3 PF08633.10 KXG52997.1 - 3.2e-65 220.3 0.1 3.2e-65 220.3 0.1 1.7 2 0 0 2 2 2 1 Rox3 mediator complex subunit Fungal_trans PF04082.18 KXG52998.1 - 1.3e-15 57.2 0.1 2.2e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ELMO_CED12 PF04727.13 KXG52998.1 - 0.17 12.0 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 ELMO/CED-12 family Fungal_trans PF04082.18 KXG52999.1 - 2.9e-20 72.4 0.1 4.1e-20 71.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG52999.1 - 4.6e-08 33.1 8.2 4.6e-08 33.1 8.2 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_2 PF00328.22 KXG53001.1 - 8e-44 150.5 0.0 9.2e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sugar_tr PF00083.24 KXG53002.1 - 3.5e-83 279.9 19.3 4.1e-83 279.7 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG53002.1 - 4.9e-18 65.2 23.6 4e-16 58.9 15.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3852 PF12963.7 KXG53002.1 - 0.018 15.4 0.3 0.061 13.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) dCMP_cyt_deam_1 PF00383.23 KXG53004.1 - 1.6e-11 43.9 0.0 2.3e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXG53004.1 - 4.9e-09 36.1 0.0 5.9e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KXG53004.1 - 0.00056 20.0 0.1 0.0014 18.8 0.2 1.5 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 KXG53004.1 - 0.019 15.1 1.3 0.09 12.8 0.3 2.1 1 1 1 2 2 2 0 Bd3614-like deaminase APOBEC3 PF18771.1 KXG53004.1 - 0.16 12.1 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 APOBEC3 DUF4449 PF14613.6 KXG53005.1 - 3.4e-61 206.1 0.3 3.4e-61 206.1 0.3 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Evr1_Alr PF04777.13 KXG53005.1 - 0.017 15.6 0.9 0.063 13.8 0.2 2.4 2 0 0 2 2 2 0 Erv1 / Alr family AIRC PF00731.20 KXG53006.1 - 1.5e-57 193.4 2.0 2.7e-57 192.5 1.5 1.7 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 KXG53006.1 - 2.9e-51 173.4 0.0 7.1e-51 172.2 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain PurK_C PF17769.1 KXG53006.1 - 2.9e-18 65.3 0.2 7.1e-18 64.1 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KXG53006.1 - 6.9e-07 29.0 0.0 1.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 KXG53006.1 - 1.1e-05 25.1 0.0 6.3e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus AlaDh_PNT_C PF01262.21 KXG53006.1 - 0.00034 20.0 0.0 0.00077 18.8 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ATP-grasp_5 PF13549.6 KXG53006.1 - 0.0029 17.1 0.0 0.0061 16.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Peptidase_M15_3 PF08291.11 KXG53006.1 - 0.011 15.8 0.1 2.9 8.0 0.0 3.5 3 0 0 3 3 3 0 Peptidase M15 PrpR_N PF06506.11 KXG53006.1 - 0.016 14.8 0.6 0.11 12.1 0.1 2.5 3 0 0 3 3 3 0 Propionate catabolism activator 2-Hacid_dh_C PF02826.19 KXG53006.1 - 0.084 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 KXG53006.1 - 0.085 13.4 0.0 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain PPP4R2 PF09184.11 KXG53007.1 - 1.7e-09 37.7 5.8 1.9e-09 37.6 3.1 2.2 1 1 0 1 1 1 1 PPP4R2 HSF_DNA-bind PF00447.17 KXG53008.1 - 3.8e-31 107.6 1.9 3.8e-31 107.6 1.9 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 KXG53008.1 - 2.1e-22 79.4 0.0 5.1e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain FTO_CTD PF12934.7 KXG53008.1 - 0.061 13.1 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 FTO C-terminal domain SlyX PF04102.12 KXG53008.1 - 0.53 10.9 8.9 0.31 11.7 5.8 2.3 2 0 0 2 2 2 0 SlyX Redoxin PF08534.10 KXG53009.1 - 1.2e-25 89.9 0.0 1.5e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXG53009.1 - 4.7e-07 29.8 0.0 6.2e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family BolA PF01722.18 KXG53010.1 - 3.5e-19 68.8 0.1 1.6e-18 66.8 0.1 2.0 2 1 0 2 2 2 1 BolA-like protein NIF3 PF01784.18 KXG53011.1 - 1e-51 175.9 0.0 1.5e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) ENTH PF01417.20 KXG53012.1 - 8.2e-48 161.6 0.1 4.3e-47 159.2 0.0 2.1 2 0 0 2 2 2 1 ENTH domain DUF1720 PF08226.11 KXG53012.1 - 6.5e-05 23.3 31.4 6.5e-05 23.3 31.4 5.7 1 1 2 3 3 3 1 Domain of unknown function (DUF1720) UIM PF02809.20 KXG53012.1 - 0.00087 19.0 4.1 0.0042 16.9 1.6 2.5 2 0 0 2 2 2 1 Ubiquitin interaction motif ANTH PF07651.16 KXG53012.1 - 0.0025 16.8 0.0 0.0039 16.2 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.6 KXG53012.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) ADP_ribosyl_GH PF03747.14 KXG53013.1 - 7.2e-57 193.3 0.1 8.3e-57 193.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase NmrA PF05368.13 KXG53014.1 - 2.6e-12 46.8 0.0 3.8e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG53014.1 - 0.0035 17.3 0.0 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXG53014.1 - 0.0036 17.6 0.0 0.0072 16.6 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KXG53014.1 - 0.097 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Chorismate_bind PF00425.18 KXG53015.1 - 1.8e-90 303.0 0.0 2.7e-90 302.4 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KXG53015.1 - 1.6e-26 93.2 0.0 1.1e-23 84.0 0.0 2.7 2 0 0 2 2 2 2 Anthranilate synthase component I, N terminal region LisH PF08513.11 KXG53015.1 - 4.1e-06 26.5 0.0 9e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 LisH ANAPC4_WD40 PF12894.7 KXG53015.1 - 4.3e-06 26.9 0.0 2.4 8.5 0.0 5.0 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXG53015.1 - 0.024 13.6 0.3 4.5 6.1 0.1 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXG53015.1 - 0.055 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KXG53015.1 - 0.12 12.4 1.6 11 6.1 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 KXG53015.1 - 0.7 10.9 14.9 0.83 10.6 0.1 5.8 7 0 0 7 7 7 0 WD domain, G-beta repeat DUF1751 PF08551.10 KXG53016.1 - 1.3e-29 102.7 2.7 2.7e-29 101.7 2.7 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KXG53016.1 - 0.00017 21.6 7.1 0.00037 20.5 7.1 1.5 1 0 0 1 1 1 1 Rhomboid family DUF4149 PF13664.6 KXG53016.1 - 1.3 9.4 6.6 3.4 8.1 0.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) Rad1 PF02144.16 KXG53017.1 - 1.1e-92 310.1 0.1 1.2e-92 309.9 0.1 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ost5 PF05251.12 KXG53018.1 - 6.1e-17 61.7 9.4 7.1e-17 61.4 9.4 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Bromodomain PF00439.25 KXG53019.1 - 6.3e-23 80.7 0.8 1.3e-22 79.6 0.8 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KXG53019.1 - 2.8e-08 34.0 0.0 5.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXG53019.1 - 9.4e-07 28.8 0.1 2e-06 27.8 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXG53019.1 - 0.00031 21.1 0.1 0.00056 20.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PCI PF01399.27 KXG53020.1 - 0.00059 20.3 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 PCI domain DCA16 PF15349.6 KXG53020.1 - 0.031 13.8 0.3 0.055 13.0 0.3 1.4 1 1 0 1 1 1 0 DDB1- and CUL4-associated factor 16 Phage_Mu_Gam PF07352.12 KXG53020.1 - 0.17 11.8 1.4 0.28 11.1 1.4 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF1192 PF06698.11 KXG53020.1 - 0.17 11.9 4.6 0.45 10.6 3.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) DUF3584 PF12128.8 KXG53020.1 - 0.28 8.6 0.6 0.37 8.3 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HMA PF00403.26 KXG53021.1 - 4.4e-51 171.2 1.9 1e-12 48.3 0.1 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 KXG53021.1 - 2.3e-47 160.8 0.4 9.4e-47 158.9 0.4 2.1 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KXG53021.1 - 5.2e-36 124.9 0.1 1.2e-35 123.7 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXG53021.1 - 7.2e-05 22.6 0.4 0.00025 20.9 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase W2 PF02020.18 KXG53022.1 - 6.1e-19 67.9 6.6 6.1e-19 67.9 6.6 3.3 4 0 0 4 4 4 1 eIF4-gamma/eIF5/eIF2-epsilon IBR PF01485.21 KXG53022.1 - 4.5e-13 49.2 38.9 1.6e-07 31.4 16.8 4.4 2 2 2 4 4 4 2 IBR domain, a half RING-finger domain Hexapep PF00132.24 KXG53022.1 - 5.8e-11 41.7 12.6 2e-05 24.1 3.4 4.0 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KXG53022.1 - 1.2e-06 28.3 0.0 2.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KXG53022.1 - 9.7e-05 22.8 0.0 0.00019 21.8 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain zf-RING_2 PF13639.6 KXG53022.1 - 0.00094 19.5 4.2 0.00094 19.5 4.2 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KXG53022.1 - 0.0015 18.3 4.6 0.0015 18.3 4.6 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Hexapep_2 PF14602.6 KXG53022.1 - 0.0029 17.3 12.1 0.16 11.7 0.1 4.1 1 1 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase Spt5_N PF11942.8 KXG53022.1 - 0.017 16.1 0.2 0.017 16.1 0.2 4.3 4 0 0 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal zf-C3HC4_2 PF13923.6 KXG53022.1 - 6.3 6.7 24.3 0.046 13.6 5.4 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Mito_carr PF00153.27 KXG53023.1 - 5e-63 209.1 7.0 1.5e-22 79.3 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein AAA PF00004.29 KXG53024.1 - 5.6e-38 130.4 0.0 1.2e-37 129.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KXG53024.1 - 1.1e-08 34.9 0.0 6.8e-07 29.2 0.0 3.2 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KXG53024.1 - 1.8e-06 27.6 0.0 3.7e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KXG53024.1 - 2.3e-05 24.7 1.1 0.00024 21.4 0.2 2.9 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.14 KXG53024.1 - 6.5e-05 23.1 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KXG53024.1 - 0.00011 22.0 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXG53024.1 - 0.00088 19.3 0.1 0.0039 17.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KXG53024.1 - 0.0009 18.5 0.0 0.0016 17.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KXG53024.1 - 0.0024 18.3 0.8 0.0024 18.3 0.8 3.1 3 1 0 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 KXG53024.1 - 0.0044 16.4 0.1 0.0098 15.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXG53024.1 - 0.0066 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KXG53024.1 - 0.023 14.8 0.0 0.06 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KXG53024.1 - 0.024 13.8 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 KXG53024.1 - 0.036 14.1 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXG53024.1 - 0.065 12.8 0.0 0.24 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXG53024.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXG53024.1 - 0.092 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KXG53024.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KXG53024.1 - 0.13 12.8 0.0 0.37 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXG53024.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain COG6 PF06419.11 KXG53025.1 - 5.4e-216 718.6 0.0 6.2e-216 718.4 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.11 KXG53025.1 - 0.0049 17.0 1.0 0.02 15.0 1.0 2.1 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Transcrip_act PF04949.13 KXG53025.1 - 0.014 15.3 2.4 0.017 15.0 1.1 1.9 2 0 0 2 2 2 0 Transcriptional activator Laminin_II PF06009.12 KXG53025.1 - 0.08 13.0 1.2 0.23 11.5 1.2 1.7 1 0 0 1 1 1 0 Laminin Domain II GARP PF16731.5 KXG53025.1 - 0.081 12.6 1.8 0.12 12.0 0.8 1.8 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF948 PF06103.11 KXG53025.1 - 0.52 10.6 2.1 1.4 9.3 0.7 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Herpes_BLRF2 PF05812.12 KXG53026.1 - 0.069 13.3 1.9 0.097 12.8 0.3 2.1 3 1 0 3 3 3 0 Herpesvirus BLRF2 protein FapA PF03961.13 KXG53026.1 - 0.14 10.8 0.8 0.2 10.2 0.4 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Tmemb_cc2 PF10267.9 KXG53026.1 - 0.25 10.4 7.1 0.6 9.2 0.3 2.6 1 1 2 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein DUF1451 PF07295.11 KXG53026.1 - 0.42 10.6 4.2 0.92 9.5 0.3 2.5 1 1 1 2 2 2 0 Zinc-ribbon containing domain Laminin_II PF06009.12 KXG53026.1 - 0.64 10.0 5.6 0.55 10.2 0.5 2.6 2 1 1 3 3 3 0 Laminin Domain II Pox_A_type_inc PF04508.12 KXG53026.1 - 3.8 7.5 5.7 45 4.1 0.0 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat APG6_N PF17675.1 KXG53026.1 - 7.8 7.0 20.6 32 5.0 0.2 3.3 2 2 0 2 2 2 0 Apg6 coiled-coil region HSP9_HSP12 PF04119.12 KXG53027.1 - 4e-27 94.4 10.6 5e-27 94.1 9.9 1.5 2 0 0 2 2 2 1 Heat shock protein 9/12 YtxH PF12732.7 KXG53027.1 - 0.26 11.9 3.4 0.29 11.7 2.5 1.7 1 1 0 1 1 1 0 YtxH-like protein NYN PF01936.18 KXG53028.1 - 6.3e-05 23.5 0.0 0.001 19.6 0.0 2.8 1 1 0 1 1 1 1 NYN domain Mog1 PF04603.12 KXG53029.1 - 5.5e-28 98.1 0.0 1.5e-27 96.6 0.0 1.7 1 1 0 1 1 1 1 Ran-interacting Mog1 protein SET PF00856.28 KXG53030.1 - 2.5e-09 37.7 0.0 3.3e-09 37.3 0.0 1.3 1 1 0 1 1 1 1 SET domain GMC_oxred_N PF00732.19 KXG53031.1 - 1.1e-08 34.9 0.0 2.1e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG53031.1 - 2.8e-08 34.4 0.0 6.8e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXG53031.1 - 5.7e-05 22.4 0.2 8.7e-05 21.8 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXG53031.1 - 0.01 16.1 0.9 0.035 14.3 0.9 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG53031.1 - 0.025 13.8 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXG53031.1 - 0.16 11.3 3.3 0.27 10.5 3.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase SprT-like PF10263.9 KXG53032.1 - 2.4e-27 95.1 0.3 4.7e-27 94.1 0.3 1.5 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KXG53032.1 - 0.019 14.8 2.9 0.041 13.8 2.9 1.6 1 0 0 1 1 1 0 SprT-like zinc ribbon domain SpdB PF05122.13 KXG53032.1 - 0.031 14.4 0.2 0.096 12.8 0.2 1.8 1 0 0 1 1 1 0 Mobile element transfer protein SPT6_acidic PF14632.6 KXG53032.1 - 0.25 12.0 3.7 0.97 10.1 3.7 2.0 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Glucan_synthase PF02364.15 KXG53033.1 - 0 1377.3 0.0 0 1376.8 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KXG53033.1 - 3.5e-43 147.0 0.9 9.7e-43 145.6 0.9 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.21 KXG53033.1 - 8.6e-40 137.0 0.0 1.3e-39 136.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXG53033.1 - 0.085 11.4 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_17 PF00332.18 KXG53034.1 - 3.8e-06 26.7 0.0 2.6e-05 24.0 0.0 2.2 3 0 0 3 3 3 1 Glycosyl hydrolases family 17 DUF3043 PF11241.8 KXG53035.1 - 5.3 7.1 7.0 0.36 10.8 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) WD40 PF00400.32 KXG53036.1 - 2.3e-07 31.4 1.1 2.6 9.0 0.1 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat RasGAP PF00616.19 KXG53037.1 - 5.4e-30 104.7 0.0 1.7e-20 73.6 0.0 2.8 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KXG53037.1 - 2.8e-06 27.5 0.1 2.8e-05 24.3 0.1 2.4 1 1 0 1 1 1 1 C2 domain APG9 PF04109.16 KXG53038.1 - 5.6e-210 698.4 10.2 6.5e-210 698.1 10.2 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Ifi-6-16 PF06140.13 KXG53039.1 - 1.4e-06 28.1 0.2 1.4e-06 28.1 0.2 1.8 2 0 0 2 2 2 1 Interferon-induced 6-16 family DUF4404 PF14357.6 KXG53039.1 - 0.02 15.5 0.0 0.03 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Dodecin PF07311.12 KXG53039.1 - 0.35 11.2 1.6 1.9 8.8 0.1 2.5 2 1 1 3 3 3 0 Dodecin Glyco_hydro_47 PF01532.20 KXG53040.1 - 2.7e-181 603.4 0.1 7.1e-181 602.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 DUF2013 PF09431.10 KXG53040.1 - 7.2e-51 172.0 0.2 7.2e-51 172.0 0.2 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2013) COQ9 PF08511.11 KXG53041.1 - 3.1e-23 81.3 0.1 5.5e-23 80.5 0.1 1.3 1 0 0 1 1 1 1 COQ9 RRM_1 PF00076.22 KXG53042.1 - 1.4e-54 181.8 0.0 1.3e-17 63.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXG53042.1 - 7.4e-06 25.6 0.0 0.0019 17.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KXG53042.1 - 0.00032 20.7 0.0 14 5.8 0.0 4.4 3 2 0 3 3 3 2 Limkain b1 RRM_3 PF08777.11 KXG53042.1 - 0.00078 19.5 0.0 3.5 7.7 0.0 3.4 3 1 0 3 3 3 2 RNA binding motif PknH_C PF14032.6 KXG53042.1 - 0.0015 18.4 0.3 9.4 6.0 0.1 3.2 3 0 0 3 3 3 2 PknH-like extracellular domain ATP-grasp_2 PF08442.10 KXG53042.1 - 0.076 12.6 0.0 0.66 9.5 0.0 2.3 3 0 0 3 3 3 0 ATP-grasp domain RRM_Rrp7 PF17799.1 KXG53042.1 - 0.19 11.5 0.0 24 4.7 0.0 2.9 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain PH PF00169.29 KXG53043.1 - 5.3e-06 26.9 0.1 6e-05 23.5 0.1 2.3 2 0 0 2 2 2 1 PH domain DUF3921 PF13060.6 KXG53043.1 - 0.032 14.3 0.0 0.078 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) P4Ha_N PF08336.11 KXG53043.1 - 0.089 12.8 0.1 0.26 11.3 0.1 1.8 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Tim17 PF02466.19 KXG53044.1 - 4.2e-07 30.3 6.6 9e-07 29.3 6.0 1.9 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Na_H_antiport_3 PF07399.11 KXG53044.1 - 0.16 10.8 1.0 0.22 10.3 1.0 1.1 1 0 0 1 1 1 0 Putative Na+/H+ antiporter UCH PF00443.29 KXG53045.1 - 4.5e-45 154.1 0.0 1.3e-44 152.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KXG53045.1 - 6e-45 151.0 0.3 2.1e-16 59.6 0.0 4.5 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.6 KXG53045.1 - 0.00071 19.3 0.0 0.0029 17.2 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SNF2_N PF00176.23 KXG53046.1 - 4.5e-13 48.6 0.0 5.1e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KXG53046.1 - 0.0013 18.7 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXG53046.1 - 0.007 16.2 0.0 0.009 15.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase CoA_trans PF01144.23 KXG53047.1 - 1.5e-101 338.3 0.7 9.9e-61 204.9 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF2370 PF10176.9 KXG53049.1 - 2.6e-91 305.3 0.1 5.8e-91 304.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) DUF2561 PF10812.8 KXG53049.1 - 0.051 13.6 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DUF3632 PF12311.8 KXG53050.1 - 2.5e-22 80.2 1.2 2.9e-22 80.0 0.7 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) eIF3m_C_helix PF18005.1 KXG53050.1 - 0.029 14.1 0.9 0.029 14.1 0.9 2.1 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix DUF3678 PF12435.8 KXG53050.1 - 4.2 6.8 7.6 6.3 6.3 1.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Toxin_8 PF07365.12 KXG53051.1 - 3 8.1 5.8 26 5.1 0.2 3.3 3 0 0 3 3 3 0 Alpha conotoxin precursor Pkinase PF00069.25 KXG53053.1 - 7.3e-68 228.8 0.0 1.2e-67 228.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG53053.1 - 3.1e-31 108.6 0.0 4.9e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXG53053.1 - 0.011 14.7 0.0 0.023 13.6 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KXG53053.1 - 0.044 13.1 0.0 0.092 12.1 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXG53053.1 - 0.047 13.6 0.3 0.17 11.8 0.0 2.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family GP67 PF17634.2 KXG53054.1 - 2.5 8.6 15.1 4.3 7.8 15.1 1.3 1 0 0 1 1 1 0 Gene product 67 tRNA-synt_2b PF00587.25 KXG53055.1 - 9.7e-31 107.1 0.1 2.8e-28 99.1 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXG53055.1 - 2.1e-15 56.6 0.8 5.5e-15 55.3 0.1 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.14 KXG53055.1 - 1e-14 54.3 0.0 2.1e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KXG53055.1 - 2.6e-05 24.2 0.0 5.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.14 KXG53056.1 - 3.4e-39 134.1 0.0 4e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.21 KXG53057.1 - 5.6e-12 46.3 0.7 1.5e-11 44.9 0.1 2.0 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Cation_efflux PF01545.21 KXG53057.1 - 0.097 12.4 2.9 2.2 8.0 0.1 2.1 2 0 0 2 2 2 0 Cation efflux family WSC PF01822.19 KXG53058.1 - 4.4e-12 46.0 8.2 4.4e-12 46.0 8.2 2.0 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 KXG53058.1 - 1.7e-09 36.9 1.5 1.7e-09 36.9 1.5 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4366 PF14283.6 KXG53058.1 - 0.0068 16.5 0.3 0.011 15.8 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) TMEM154 PF15102.6 KXG53058.1 - 0.014 15.3 0.4 0.026 14.5 0.4 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 KXG53058.1 - 0.024 13.4 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2165 PF09933.9 KXG53058.1 - 0.025 14.6 0.1 0.044 13.8 0.1 1.3 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) CbtA PF09490.10 KXG53058.1 - 0.063 13.0 1.3 0.076 12.8 0.1 1.7 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Sporozoite_P67 PF05642.11 KXG53058.1 - 0.31 9.1 6.7 0.36 8.9 6.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-C2H2 PF00096.26 KXG53059.1 - 1.4e-06 28.4 12.7 0.00048 20.4 1.1 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 KXG53059.1 - 0.0019 18.8 3.1 0.85 10.3 0.3 2.4 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KXG53059.1 - 0.0052 17.5 7.8 0.57 11.2 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-CGNR PF11706.8 KXG53059.1 - 0.56 10.1 4.3 1.2 9.0 0.8 2.4 2 0 0 2 2 2 0 CGNR zinc finger G_glu_transpept PF01019.21 KXG53060.1 - 2.8e-139 465.2 0.1 3.4e-139 464.9 0.1 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase HalOD2 PF18547.1 KXG53061.1 - 0.066 13.1 0.5 0.066 13.1 0.5 3.4 4 0 0 4 4 4 0 Halobacterial output domain 2 Nudix_N_2 PF14803.6 KXG53061.1 - 3.2 7.8 11.2 4.9 7.2 2.0 3.5 3 1 0 3 3 3 0 Nudix N-terminal Trypan_PARP PF05887.11 KXG53062.1 - 0.01 15.8 41.5 0.01 15.8 41.5 20.0 3 1 12 15 15 15 0 Procyclic acidic repetitive protein (PARP) MFS_1 PF07690.16 KXG53063.1 - 2.7e-47 161.4 33.5 2.7e-47 161.4 33.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG53063.1 - 1.7e-11 43.6 8.7 1.7e-11 43.6 8.7 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 KXG53063.1 - 2.9e-05 23.5 12.8 3.2e-05 23.4 4.0 2.7 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KXG53063.1 - 0.47 8.7 13.6 1.5 7.0 0.2 3.1 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TPMT PF05724.11 KXG53064.1 - 1e-26 94.0 0.0 3.5e-26 92.2 0.0 1.7 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 KXG53064.1 - 1.2e-05 25.9 0.0 2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG53064.1 - 0.00021 21.9 0.0 0.00037 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG53064.1 - 0.0016 18.3 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG53064.1 - 0.0094 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG53064.1 - 0.033 14.9 0.0 0.057 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain N2227 PF07942.12 KXG53064.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein OTU PF02338.19 KXG53065.1 - 5.7e-20 72.1 0.3 5.3e-19 69.0 0.3 2.2 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KXG53065.1 - 7.7e-06 25.5 0.0 0.00059 19.4 0.0 2.4 2 0 0 2 2 2 2 Peptidase C65 Otubain Cep57_MT_bd PF06657.13 KXG53065.1 - 0.099 13.1 5.6 0.24 11.9 5.6 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 adh_short_C2 PF13561.6 KXG53066.1 - 8e-45 153.2 0.0 9.4e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG53066.1 - 2.4e-43 147.9 0.0 3.3e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG53066.1 - 7.5e-06 26.0 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 KR domain T3SchapCesA PF11439.8 KXG53066.1 - 0.12 12.5 0.1 0.22 11.7 0.1 1.3 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA Trehalase PF01204.18 KXG53067.1 - 1.9e-191 637.4 0.0 2.3e-191 637.1 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KXG53067.1 - 5e-17 61.3 0.4 1e-16 60.4 0.4 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.21 KXG53068.1 - 2.3e-300 996.6 4.7 2.6e-300 996.4 4.7 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KXG53068.1 - 6.6e-12 45.4 0.2 1.6e-11 44.1 0.1 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Aldedh PF00171.22 KXG53069.1 - 3.2e-77 260.0 0.0 3.8e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Adap_comp_sub PF00928.21 KXG53070.1 - 2.8e-62 210.5 0.0 1e-61 208.6 0.0 1.8 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXG53070.1 - 7e-05 22.8 0.1 0.00012 22.1 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain YL1 PF05764.13 KXG53070.1 - 0.0066 16.6 2.3 0.0091 16.1 2.3 1.1 1 0 0 1 1 1 1 YL1 nuclear protein SWIRM-assoc_2 PF16496.5 KXG53070.1 - 0.83 8.5 8.1 1.2 7.9 8.1 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Rrn6 PF10214.9 KXG53070.1 - 1.7 7.1 11.3 2.3 6.6 11.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4536 PF15055.6 KXG53071.1 - 1.8e-06 28.1 5.4 9.2e-06 25.8 5.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) DUF4588 PF15251.6 KXG53072.1 - 3.1e-05 23.9 3.5 0.00021 21.1 3.4 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) SNF2_N PF00176.23 KXG53073.1 - 3.8e-78 262.7 0.1 6.1e-78 262.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KXG53073.1 - 6.3e-41 139.0 1.0 2.6e-40 137.0 1.0 2.2 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 KXG53073.1 - 6.3e-38 129.9 2.4 6.3e-38 129.9 2.4 3.4 4 0 0 4 4 3 1 HAND Helicase_C PF00271.31 KXG53073.1 - 1.1e-17 64.4 0.0 1.2e-16 61.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG53073.1 - 5.4e-12 46.0 0.6 2.1e-11 44.1 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXG53073.1 - 1.7e-05 24.7 0.0 7.7e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KXG53073.1 - 2.5e-05 23.6 0.1 0.00011 21.5 0.0 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KXG53073.1 - 8e-05 22.4 0.0 0.00025 20.8 0.0 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD_2 PF06733.15 KXG53073.1 - 0.0058 16.3 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 DUF1086 PF06461.11 KXG53073.1 - 0.063 13.1 0.1 0.2 11.5 0.1 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) AAA_22 PF13401.6 KXG53073.1 - 0.093 13.0 0.1 0.49 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KXG53073.1 - 0.27 11.3 3.7 0.17 11.9 0.1 2.5 3 0 0 3 3 3 0 AAA domain Asp PF00026.23 KXG53074.1 - 7.8e-68 229.2 4.4 9.2e-68 229.0 4.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXG53074.1 - 2.2e-12 47.6 1.0 2.4e-07 31.2 0.0 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXG53074.1 - 0.00088 19.9 2.6 0.32 11.6 0.7 3.2 2 1 0 2 2 2 2 Aspartyl protease ADH_zinc_N PF00107.26 KXG53075.1 - 1.6e-23 83.1 0.7 2.6e-23 82.4 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG53075.1 - 5.1e-19 68.2 0.7 7.8e-19 67.6 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KXG53075.1 - 4.8e-08 32.7 2.0 7.6e-08 32.1 1.5 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXG53075.1 - 0.00024 20.5 0.1 0.00047 19.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KXG53075.1 - 0.00027 22.0 0.0 0.00077 20.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KXG53075.1 - 0.05 14.3 0.1 0.11 13.3 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KXG53075.1 - 0.098 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SpoU_methylase PF00588.19 KXG53076.1 - 2.5e-24 86.1 0.1 5.6e-23 81.7 0.1 2.4 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KXG53076.1 - 4.6e-07 30.0 0.0 8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding SNF2_N PF00176.23 KXG53077.1 - 9.8e-52 175.8 0.1 1.8e-51 174.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-PHD-like PF15446.6 KXG53077.1 - 8.5e-50 168.7 8.5 3e-49 166.9 8.6 1.9 1 1 0 1 1 1 1 PHD/FYVE-zinc-finger like domain zf-CCCH_6 PF18585.1 KXG53077.1 - 8.3e-24 83.2 0.1 2.4e-23 81.8 0.1 1.9 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 KXG53077.1 - 5.7e-20 71.7 0.0 1.8e-19 70.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KXG53077.1 - 1.6e-13 50.5 1.7 3.4e-13 49.4 1.7 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KXG53077.1 - 1e-06 28.8 0.0 3.2e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Chromo PF00385.24 KXG53077.1 - 1.4e-05 24.9 3.3 0.041 13.8 0.1 3.2 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 KXG53077.1 - 4.7e-05 23.2 18.3 0.0029 17.5 7.6 3.5 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.6 KXG53077.1 - 1.8 8.2 9.7 0.05 13.2 0.9 2.8 3 0 0 3 3 3 0 PHD-finger MRP-S28 PF10213.9 KXG53080.1 - 7.4e-45 152.5 0.1 1.3e-44 151.7 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DnaB_bind PF10410.9 KXG53080.1 - 0.015 15.4 0.2 1 9.6 0.0 2.5 1 1 1 2 2 2 0 DnaB-helicase binding domain of primase Actin PF00022.19 KXG53081.1 - 4.1e-126 420.9 0.0 2.1e-125 418.6 0.0 1.9 1 1 0 1 1 1 1 Actin Glyco_tran_28_C PF04101.16 KXG53081.1 - 2.1e-19 70.1 0.1 4.8e-19 69.0 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF3602 PF12223.8 KXG53082.1 - 4.2e-24 84.9 3.0 1.5e-20 73.5 0.3 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) zf-U1 PF06220.12 KXG53085.1 - 1.5e-06 27.9 0.8 2.6e-06 27.1 0.8 1.4 1 0 0 1 1 1 1 U1 zinc finger TRP PF06011.12 KXG53086.1 - 2.1e-167 557.2 20.5 2.1e-167 557.2 20.5 1.3 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXG53086.1 - 6.2e-37 127.1 0.0 9.7e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Ac76 PF05814.11 KXG53086.1 - 3 7.9 10.9 4.2 7.5 0.1 3.5 3 0 0 3 3 3 0 Orf76 (Ac76) DHHC PF01529.20 KXG53086.1 - 3.8 7.6 12.0 1.6 8.8 1.6 3.1 2 1 0 2 2 2 0 DHHC palmitoyltransferase DEAD PF00270.29 KXG53087.1 - 2.6e-46 157.6 0.1 4.6e-46 156.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG53087.1 - 1.2e-23 83.5 0.0 8.4e-23 80.8 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXG53087.1 - 7.6e-18 64.5 0.1 1.4e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXG53087.1 - 5.6e-05 23.2 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXG53087.1 - 0.00069 18.9 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase T-box_assoc PF16176.5 KXG53087.1 - 0.33 11.0 7.2 0.52 10.4 7.2 1.2 1 0 0 1 1 1 0 T-box transcription factor-associated SWIRM-assoc_2 PF16496.5 KXG53087.1 - 1.7 7.5 11.6 2.7 6.7 11.6 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal HeLo PF14479.6 KXG53089.1 - 4.3e-16 59.4 0.0 1.4e-15 57.7 0.0 1.9 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 KXG53089.1 - 0.005 16.2 0.0 0.0099 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXG53089.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Ank_2 PF12796.7 KXG53090.1 - 1.9e-20 73.2 0.2 0.00029 21.4 0.1 5.8 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Pkinase PF00069.25 KXG53090.1 - 1e-18 67.6 0.0 1.7e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG53090.1 - 1.1e-16 60.9 0.0 1.9e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 KXG53090.1 - 7.7e-16 56.6 0.4 0.00032 20.9 0.0 8.0 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 KXG53090.1 - 2.2e-14 53.6 5.2 5e-05 23.8 0.1 8.2 4 2 6 10 10 10 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG53090.1 - 2.7e-12 46.6 5.6 6.7e-06 26.3 0.1 4.9 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 KXG53090.1 - 6.9e-12 45.2 9.5 0.0039 17.6 0.1 8.6 9 0 0 9 9 9 2 Ankyrin repeat Pkinase_fungal PF17667.1 KXG53090.1 - 0.023 13.5 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Hydrolase PF00702.26 KXG53092.1 - 8.6e-17 62.1 0.0 1.9e-13 51.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXG53092.1 - 4.4e-13 49.7 0.0 6.8e-12 45.8 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXG53092.1 - 2.1e-05 24.5 0.1 4.5e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like PGP_phosphatase PF09419.10 KXG53092.1 - 0.0087 15.7 0.0 0.55 9.8 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase HAD PF12710.7 KXG53092.1 - 0.012 16.0 0.1 0.16 12.3 0.1 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ORMDL PF04061.14 KXG53094.1 - 2.5e-58 195.7 3.1 2.9e-58 195.5 3.1 1.0 1 0 0 1 1 1 1 ORMDL family PI3K_C2 PF00792.24 KXG53094.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 PBP1_TM PF14812.6 KXG53095.1 - 1 9.8 5.0 3.6 8.0 5.0 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CH PF00307.31 KXG53096.1 - 8.6e-16 58.1 0.0 1.6e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF4677 PF15726.5 KXG53096.1 - 0.44 10.7 1.9 1.4 9.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4677) NDUFA12 PF05071.16 KXG53097.1 - 1.1e-10 42.1 10.0 5.5e-10 40.0 10.0 2.2 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF5364 PF17322.2 KXG53097.1 - 0.015 15.6 0.2 0.02 15.2 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5364) Piwi PF02171.17 KXG53098.1 - 2.2e-67 227.4 0.0 3.4e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 KXG53098.1 - 2.2e-12 46.9 0.0 5.8e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 KXG53098.1 - 4.6e-12 45.4 0.1 1.2e-11 44.1 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 KXG53098.1 - 2e-10 41.4 0.0 1.3e-09 38.8 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL2 PF16488.5 KXG53098.1 - 2.2e-08 34.3 0.1 5.5e-08 33.0 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KXG53098.1 - 0.00012 22.3 0.0 0.00026 21.2 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute DUF3580 PF12117.8 KXG53102.1 - 3.8 7.8 6.4 0.47 10.7 0.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3580) EMP24_GP25L PF01105.24 KXG53103.1 - 3e-40 138.1 0.0 3.3e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 KXG53103.1 - 0.098 10.8 0.4 0.12 10.5 0.4 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Sdh5 PF03937.16 KXG53104.1 - 1.7e-22 79.1 0.1 5.2e-22 77.6 0.2 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase WD40 PF00400.32 KXG53105.1 - 1.6e-44 149.0 24.0 3e-09 37.4 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG53105.1 - 1.9e-09 37.7 0.4 0.049 13.9 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXG53105.1 - 1.1e-05 24.3 5.5 0.093 11.4 0.1 4.6 2 1 3 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXG53105.1 - 0.0044 16.0 0.1 12 4.8 0.0 3.9 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KXG53105.1 - 0.005 15.4 0.0 1.3 7.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 KXG53105.1 - 0.016 15.1 0.5 20 5.3 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KXG53105.1 - 0.046 13.0 0.0 1.1 8.5 0.0 2.3 2 1 0 2 2 2 0 WD40-like domain TPR_1 PF00515.28 KXG53106.1 - 0.0021 17.8 10.4 0.016 15.0 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXG53106.1 - 0.0033 17.7 0.7 0.0033 17.7 0.7 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXG53106.1 - 0.0093 15.8 1.3 0.0093 15.8 1.3 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat FumaraseC_C PF10415.9 KXG53106.1 - 0.038 14.4 0.2 0.25 11.8 0.0 2.5 2 0 0 2 2 2 0 Fumarase C C-terminus TPR_8 PF13181.6 KXG53106.1 - 0.1 12.9 0.5 0.1 12.9 0.5 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat SRAP PF02586.14 KXG53107.1 - 7.3e-78 261.1 0.0 1.2e-77 260.4 0.0 1.3 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Med1 PF10744.9 KXG53110.1 - 1.1e-122 410.1 0.0 1.4e-122 409.7 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Dynein_heavy PF03028.15 KXG53110.1 - 0.031 14.4 0.2 0.057 13.5 0.2 1.3 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain Gln-synt_C PF00120.24 KXG53111.1 - 9.1e-15 54.5 0.0 4e-12 45.8 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KXG53111.1 - 4.1e-13 48.9 0.0 8.3e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MFS_1 PF07690.16 KXG53112.1 - 3.6e-31 108.4 31.0 3.6e-31 108.4 31.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Imm57 PF15596.6 KXG53112.1 - 2.9e-05 24.3 0.0 5.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Immunity protein 57 FPN1 PF06963.12 KXG53112.1 - 0.009 14.6 2.4 0.034 12.7 2.4 1.9 1 0 0 1 1 1 1 Ferroportin1 (FPN1) UNC-93 PF05978.16 KXG53112.1 - 0.3 10.8 6.4 0.22 11.2 4.2 1.8 1 1 1 2 2 2 0 Ion channel regulatory protein UNC-93 Gemini_C4 PF01492.17 KXG53113.1 - 7.9 6.5 11.3 5.3 7.0 0.9 2.3 2 0 0 2 2 2 0 Geminivirus C4 protein Sugar_tr PF00083.24 KXG53114.1 - 4.3e-109 365.4 21.4 5.3e-109 365.1 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG53114.1 - 3.3e-19 69.0 31.4 3.5e-14 52.5 8.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXG53114.1 - 6.5e-05 21.4 2.4 6.5e-05 21.4 2.4 2.2 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family TPR_19 PF14559.6 KXG53114.1 - 0.042 14.3 0.0 0.083 13.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat YbjN PF10722.9 KXG53114.1 - 0.12 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative bacterial sensory transduction regulator zf-CCHC PF00098.23 KXG53115.1 - 3.6e-56 184.9 106.2 1.5e-06 28.0 1.9 12.3 12 0 0 12 12 12 12 Zinc knuckle zf-CCHC_3 PF13917.6 KXG53115.1 - 1.5e-11 44.0 77.1 0.048 13.6 0.0 11.6 3 2 7 10 10 10 8 Zinc knuckle zf-CCHC_4 PF14392.6 KXG53115.1 - 7.6e-11 41.6 74.0 0.036 13.8 0.2 12.0 12 0 0 12 12 12 7 Zinc knuckle zf-CCHC_2 PF13696.6 KXG53115.1 - 6.6e-06 25.8 8.9 3.3e-05 23.6 1.4 12.0 12 0 0 12 12 12 7 Zinc knuckle zf-CCHC_6 PF15288.6 KXG53115.1 - 0.016 15.0 0.9 0.016 15.0 0.9 11.2 11 0 0 11 11 11 0 Zinc knuckle zf-C2H2_10 PF16588.5 KXG53115.1 - 0.29 10.9 0.1 0.29 10.9 0.1 9.7 10 0 0 10 10 10 0 C2H2 zinc-finger DUF846 PF05832.12 KXG53116.1 - 9.2e-47 158.6 10.1 1.1e-46 158.3 10.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) HpcH_HpaI PF03328.14 KXG53117.1 - 1.5e-40 138.7 0.0 1e-39 136.0 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KXG53117.1 - 2e-11 43.7 0.0 1.1e-05 24.8 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF1771 PF08590.10 KXG53118.1 - 4e-15 55.9 11.2 8.5e-15 54.9 10.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KXG53118.1 - 7.6e-10 39.0 0.1 3.3e-09 37.0 0.1 2.1 1 0 0 1 1 1 1 Smr domain zf_CCCH_4 PF18345.1 KXG53118.1 - 9.4e-08 31.9 9.4 2.1e-05 24.4 1.2 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KXG53118.1 - 2.4e-06 27.3 2.0 0.0045 16.9 0.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KXG53118.1 - 0.00014 22.0 2.3 0.2 11.9 0.0 2.4 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KXG53118.1 - 0.00025 20.7 12.4 0.0046 16.7 1.5 3.1 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KXG53118.1 - 0.00033 21.0 6.1 0.18 12.3 1.0 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger CUE PF02845.16 KXG53118.1 - 0.14 11.9 1.7 0.23 11.2 0.1 2.1 2 0 0 2 2 2 0 CUE domain Torus PF16131.5 KXG53118.1 - 0.57 10.9 3.2 2 9.1 0.8 2.5 1 1 1 2 2 2 0 Torus domain Amino_oxidase PF01593.24 KXG53119.1 - 2.4e-82 277.6 0.0 4.9e-71 240.3 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 KXG53119.1 - 2.5e-13 50.2 0.2 9.2e-13 48.4 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain NAD_binding_8 PF13450.6 KXG53119.1 - 3.7e-07 30.3 0.0 8.2e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 KXG53119.1 - 0.00027 21.3 1.8 0.00064 20.1 1.8 1.7 1 1 0 1 1 1 1 HMG (high mobility group) box DAO PF01266.24 KXG53119.1 - 0.00086 19.0 0.1 0.0017 18.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXG53119.1 - 0.021 14.0 0.1 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HyaE PF07449.11 KXG53119.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE HMG_box_2 PF09011.10 KXG53119.1 - 0.14 12.8 0.9 0.29 11.7 0.9 1.6 1 0 0 1 1 1 0 HMG-box domain Pyr_redox_2 PF07992.14 KXG53120.1 - 3.8e-48 164.2 0.2 4.5e-48 164.0 0.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG53120.1 - 1.5e-18 67.1 0.2 2.4e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG53120.1 - 7.7e-15 55.2 0.1 9.1e-13 48.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KXG53120.1 - 9.5e-05 22.8 0.2 0.015 15.7 0.0 3.1 2 2 1 3 3 3 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KXG53120.1 - 0.00017 21.7 0.7 0.067 13.4 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXG53120.1 - 0.00053 19.3 1.3 0.002 17.4 0.1 2.2 2 1 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KXG53120.1 - 0.0033 16.6 0.2 0.38 9.9 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KXG53120.1 - 0.022 14.0 0.8 9.9 5.3 0.0 2.8 2 1 1 3 3 3 0 FAD binding domain DAO PF01266.24 KXG53120.1 - 0.022 14.3 1.7 1.1 8.8 0.0 3.3 3 1 1 4 4 4 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXG53120.1 - 0.023 14.0 0.2 0.15 11.4 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KXG53120.1 - 0.05 12.7 5.6 7.8 5.5 0.1 4.1 3 2 1 5 5 5 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXG53120.1 - 0.074 12.1 4.0 0.78 8.7 0.2 3.6 3 1 2 5 5 5 0 FAD binding domain PhoD PF09423.10 KXG53121.1 - 0.0001 21.4 0.0 0.0021 17.2 0.0 2.3 1 1 0 1 1 1 1 PhoD-like phosphatase Peptidase_S8 PF00082.22 KXG53122.1 - 6.3e-37 127.4 0.3 6.3e-37 127.4 0.3 1.7 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 KXG53122.1 - 1.3e-26 92.5 0.5 2.6e-26 91.5 0.5 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KXG53122.1 - 0.034 14.9 0.0 0.088 13.6 0.0 1.7 1 0 0 1 1 1 0 Peptidase S8 pro-domain PX PF00787.24 KXG53123.1 - 4.7e-19 68.4 0.2 8.7e-19 67.6 0.2 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KXG53123.1 - 9.6e-15 54.8 5.5 2e-07 30.8 0.5 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Sec34 PF04136.15 KXG53123.1 - 0.016 15.1 0.1 0.042 13.7 0.0 1.8 2 1 0 2 2 2 0 Sec34-like family BAR PF03114.18 KXG53123.1 - 0.049 13.3 5.5 0.42 10.2 0.2 2.4 2 1 1 3 3 3 0 BAR domain FlaC_arch PF05377.11 KXG53123.1 - 0.12 12.7 0.7 28 5.2 0.4 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.13 KXG53123.1 - 0.41 11.4 3.7 2 9.2 0.0 3.0 3 0 0 3 3 3 0 Occludin homology domain DUF1664 PF07889.12 KXG53123.1 - 0.46 10.5 2.1 11 6.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FAD_binding_3 PF01494.19 KXG53124.1 - 4.2e-22 78.9 0.2 3.6e-20 72.5 0.2 2.9 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KXG53124.1 - 1.5e-06 27.5 0.0 2.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 KXG53124.1 - 0.0056 15.8 0.1 0.02 13.9 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXG53124.1 - 0.013 14.8 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG53124.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXG53124.1 - 0.086 11.7 0.1 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.6 KXG53124.1 - 0.096 11.8 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KXG53124.1 - 0.1 11.3 0.1 0.15 10.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Mlf1IP PF10248.9 KXG53124.1 - 0.1 12.6 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Thi4 PF01946.17 KXG53124.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NADH_dehy_S2_C PF06444.11 KXG53124.1 - 0.72 10.4 2.9 0.88 10.1 0.1 2.5 3 0 0 3 3 2 0 NADH dehydrogenase subunit 2 C-terminus tRNA-synt_His PF13393.6 KXG53125.1 - 9.8e-37 126.9 0.0 1.3e-30 106.7 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KXG53125.1 - 2.8e-10 40.2 0.0 5.3e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KXG53125.1 - 0.0002 21.4 0.0 0.00033 20.7 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 KXG53125.1 - 0.031 13.8 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs UCH PF00443.29 KXG53126.1 - 3e-56 190.8 1.1 3.2e-56 190.7 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXG53126.1 - 9.7e-29 101.0 0.3 6e-28 98.4 0.3 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KXG53126.1 - 0.00068 19.2 2.9 0.054 13.0 2.6 2.9 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Yos1 PF08571.10 KXG53127.1 - 1.5e-36 124.5 0.9 1.6e-36 124.4 0.9 1.0 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.17 KXG53128.1 - 2.4e-40 139.1 11.8 3.3e-40 138.6 11.8 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF1772 PF08592.11 KXG53128.1 - 0.00031 21.1 0.9 0.00031 21.1 0.9 3.5 3 1 1 4 4 4 1 Domain of unknown function (DUF1772) Dynamitin PF04912.14 KXG53129.1 - 1.5e-72 245.1 14.5 2.8e-71 240.9 14.5 2.0 1 1 0 1 1 1 1 Dynamitin Jnk-SapK_ap_N PF09744.9 KXG53129.1 - 6.7e-05 23.2 9.6 0.0041 17.4 0.6 3.0 3 0 0 3 3 3 2 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 KXG53129.1 - 0.0079 16.2 2.0 0.0079 16.2 2.0 4.1 4 0 0 4 4 4 1 TPR/MLP1/MLP2-like protein FapA PF03961.13 KXG53129.1 - 0.01 14.5 0.2 0.099 11.2 0.0 2.0 2 0 0 2 2 2 1 Flagellar Assembly Protein A DUF1664 PF07889.12 KXG53129.1 - 0.011 15.8 0.1 0.14 12.1 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 KXG53129.1 - 0.022 14.8 0.4 0.022 14.8 0.4 3.9 4 2 0 4 4 4 0 Designed helical repeat protein 10 domain SlyX PF04102.12 KXG53129.1 - 0.024 15.3 5.7 1.4 9.6 0.7 4.7 6 1 1 7 7 4 0 SlyX Laminin_II PF06009.12 KXG53129.1 - 0.063 13.3 0.1 0.063 13.3 0.1 3.3 3 2 0 3 3 3 0 Laminin Domain II Fmp27_WPPW PF10359.9 KXG53129.1 - 0.087 11.7 5.4 1.8 7.3 0.2 2.4 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain CCDC32 PF14989.6 KXG53129.1 - 0.095 12.7 2.0 0.38 10.7 0.4 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing 32 PhaP_Bmeg PF09602.10 KXG53129.1 - 0.12 12.3 1.7 2.1 8.3 0.2 2.5 2 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Spectrin PF00435.21 KXG53129.1 - 0.14 12.7 4.3 1.6 9.3 0.6 3.3 3 0 0 3 3 3 0 Spectrin repeat Cnn_1N PF07989.11 KXG53129.1 - 0.16 12.2 1.5 9.2 6.5 0.1 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF4618 PF15397.6 KXG53129.1 - 0.19 11.1 2.4 8.6 5.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Golgin_A5 PF09787.9 KXG53129.1 - 0.2 11.1 5.7 0.97 8.8 0.3 2.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF4407 PF14362.6 KXG53129.1 - 0.21 10.9 18.3 0.061 12.7 8.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) DUF2408 PF10303.9 KXG53129.1 - 0.21 12.1 3.5 17 6.0 3.5 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) MbeD_MobD PF04899.12 KXG53129.1 - 0.27 11.4 3.7 2 8.6 0.8 3.3 4 0 0 4 4 3 0 MbeD/MobD like Spc7 PF08317.11 KXG53129.1 - 0.27 10.1 8.2 0.15 10.9 0.6 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein Prefoldin_2 PF01920.20 KXG53129.1 - 0.34 10.9 6.5 0.58 10.1 0.8 2.8 3 0 0 3 3 2 0 Prefoldin subunit Spc24 PF08286.11 KXG53129.1 - 0.35 11.1 8.6 0.61 10.4 0.4 3.2 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 Rho_Binding PF08912.11 KXG53129.1 - 0.43 11.4 3.5 1.9 9.4 0.3 3.0 3 0 0 3 3 3 0 Rho Binding Syntaxin-6_N PF09177.11 KXG53129.1 - 0.44 11.1 8.3 2.3 8.8 0.6 3.1 3 0 0 3 3 2 0 Syntaxin 6, N-terminal Prefoldin PF02996.17 KXG53129.1 - 0.9 9.5 6.0 0.62 10.0 0.5 3.0 3 1 0 3 3 2 0 Prefoldin subunit CorA PF01544.18 KXG53129.1 - 0.91 8.8 4.8 0.86 8.9 0.5 2.6 2 1 2 4 4 4 0 CorA-like Mg2+ transporter protein ZapB PF06005.12 KXG53129.1 - 1.4 9.4 5.5 30 5.1 1.2 3.6 3 0 0 3 3 3 0 Cell division protein ZapB DUF2203 PF09969.9 KXG53129.1 - 3.4 8.4 8.9 2.1 9.1 0.2 3.6 2 2 3 5 5 4 0 Uncharacterized conserved protein (DUF2203) DUF4200 PF13863.6 KXG53129.1 - 4.3 7.7 8.2 0.57 10.6 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DUF1192 PF06698.11 KXG53129.1 - 5.7 7.1 21.5 0.32 11.1 2.2 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) DivIC PF04977.15 KXG53129.1 - 5.8 6.8 10.1 4.1 7.2 0.2 3.5 3 1 0 3 3 3 0 Septum formation initiator GvpK PF05121.12 KXG53129.1 - 6 7.0 7.4 5 7.2 0.8 3.4 3 1 0 3 3 3 0 Gas vesicle protein K Fez1 PF06818.15 KXG53129.1 - 9.7 6.6 11.0 7.2 7.0 2.8 2.5 2 1 0 2 2 2 0 Fez1 Aldedh PF00171.22 KXG53131.1 - 1.3e-136 455.9 0.5 1.5e-136 455.6 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXG53131.1 - 0.053 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) PGM_PMM_II PF02879.16 KXG53131.1 - 0.15 12.7 0.0 0.56 10.9 0.0 2.0 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Calreticulin PF00262.18 KXG53132.1 - 7.6e-168 558.1 16.2 1.1e-167 557.5 16.2 1.3 1 0 0 1 1 1 1 Calreticulin family DUF1911 PF08929.10 KXG53132.1 - 0.077 13.8 0.1 0.19 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) OAD_gamma PF04277.13 KXG53132.1 - 3 8.5 4.6 3.9 8.2 0.5 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Aldolase_II PF00596.21 KXG53133.1 - 1.9e-41 142.1 0.0 2.7e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain CTV_P6 PF06706.11 KXG53133.1 - 0.045 13.5 0.8 0.11 12.2 0.8 1.6 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein Vps5 PF09325.10 KXG53134.1 - 2e-87 292.7 5.2 2e-87 292.7 5.2 1.3 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 KXG53134.1 - 3.9e-24 84.8 0.1 8.7e-24 83.7 0.0 1.6 2 0 0 2 2 2 1 PX domain BAR_2 PF10455.9 KXG53134.1 - 0.0022 17.2 0.6 0.0032 16.7 0.6 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KXG53134.1 - 0.02 14.6 6.9 0.41 10.3 2.2 2.5 1 1 1 2 2 2 0 BAR domain of APPL family DUF3450 PF11932.8 KXG53134.1 - 0.025 13.9 5.2 0.053 12.8 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Flavin_Reduct PF01613.18 KXG53136.1 - 1.7e-28 99.6 0.1 2.3e-28 99.2 0.1 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Nas2_N PF18265.1 KXG53137.1 - 0.092 12.7 4.0 0.13 12.2 0.8 2.6 2 0 0 2 2 2 0 Nas2 N_terminal domain NUDIX PF00293.28 KXG53138.1 - 1.6e-15 57.3 0.0 2.2e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain 4HBT_2 PF13279.6 KXG53139.1 - 1.8e-09 38.1 0.0 2.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily MAM PF00629.23 KXG53139.1 - 0.014 15.3 0.1 0.017 15.1 0.1 1.1 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu DUF4080 PF13311.6 KXG53139.1 - 0.03 14.5 0.1 0.03 14.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) Methyltransf_25 PF13649.6 KXG53140.1 - 1.1e-09 38.9 0.0 2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG53140.1 - 1.3e-06 29.0 0.0 2.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG53140.1 - 3.8e-05 23.6 0.0 6.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG53140.1 - 0.00054 19.4 0.0 0.0011 18.3 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KXG53140.1 - 0.0029 17.4 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Exo_endo_phos PF03372.23 KXG53141.1 - 1.4e-16 60.7 0.0 9.4e-16 58.0 0.0 2.2 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KXG53141.1 - 4.3e-16 58.4 23.4 5.7e-08 32.4 6.0 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KXG53141.1 - 4.2e-12 46.1 7.1 1.5e-07 31.6 0.6 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXG53141.1 - 0.0066 16.8 4.9 1.1 10.1 0.1 4.6 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 KXG53141.1 - 2.7 8.3 11.8 0.18 11.9 0.4 4.2 5 0 0 5 5 5 0 Leucine Rich repeat MFS_1 PF07690.16 KXG53142.1 - 1e-34 120.0 24.6 1e-34 120.0 24.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG53142.1 - 4e-08 32.6 8.7 4e-08 32.6 8.7 3.8 2 1 2 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.13 KXG53142.1 - 1.1e-06 27.4 4.1 2e-06 26.6 4.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Keratin PF02422.16 KXG53142.1 - 0.018 14.7 0.1 0.063 13.0 0.0 1.9 2 0 0 2 2 2 0 Keratin 60KD_IMP PF02096.20 KXG53142.1 - 0.95 9.3 5.9 0.23 11.3 1.1 2.2 1 1 1 2 2 2 0 60Kd inner membrane protein FMN_red PF03358.15 KXG53143.1 - 1.6e-24 86.4 0.0 2.7e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase PGA2 PF07543.12 KXG53143.1 - 0.0084 16.1 0.1 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 Protein trafficking PGA2 Flavodoxin_2 PF02525.17 KXG53143.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin-like fold Hydrolase_4 PF12146.8 KXG53144.1 - 2.9e-47 160.9 0.0 3.6e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXG53144.1 - 1e-09 39.3 0.0 2e-09 38.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG53144.1 - 2e-09 37.5 0.2 1e-08 35.2 0.2 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S10 PF00450.22 KXG53144.1 - 0.00017 21.1 0.0 0.042 13.3 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase DLH PF01738.18 KXG53144.1 - 0.0045 16.6 0.0 0.07 12.7 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KXG53144.1 - 0.0076 15.8 0.0 0.51 9.8 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KXG53144.1 - 0.018 14.0 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KXG53144.1 - 0.16 11.8 0.0 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase GCD14 PF08704.10 KXG53145.1 - 3.7e-08 33.3 0.0 0.00083 19.1 0.0 2.4 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 KXG53145.1 - 2.3e-05 24.1 0.1 4.6e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_25 PF13649.6 KXG53145.1 - 0.0054 17.4 0.0 3.9 8.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KXG53145.1 - 0.13 12.1 0.0 19 5.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain HAD PF12710.7 KXG53146.1 - 1.4e-22 81.0 0.0 3.4e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Metallophos PF00149.28 KXG53146.1 - 6.1e-16 59.5 0.5 1.4e-15 58.3 0.1 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXG53146.1 - 9e-06 26.0 0.0 0.00022 21.5 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Put_Phosphatase PF06888.12 KXG53146.1 - 0.084 12.3 0.0 0.64 9.4 0.0 2.1 2 0 0 2 2 2 0 Putative Phosphatase TSNAXIP1_N PF15739.5 KXG53146.1 - 0.18 12.2 0.1 0.36 11.2 0.1 1.4 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus NAD_binding_1 PF00175.21 KXG53147.1 - 1.5e-06 28.8 0.0 0.00016 22.3 0.0 2.6 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KXG53147.1 - 2.1e-06 27.9 0.0 2.5e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain SopE_GEF PF07487.13 KXG53147.1 - 0.084 13.0 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 SopE GEF domain SCIMP PF15050.6 KXG53148.1 - 0.039 14.4 0.0 0.39 11.2 0.0 2.3 2 0 0 2 2 2 0 SCIMP protein TMIE PF16038.5 KXG53148.1 - 0.087 12.7 0.9 0.18 11.7 0.9 1.4 1 0 0 1 1 1 0 TMIE protein GATA PF00320.27 KXG53149.1 - 7.3e-15 54.3 4.7 7.3e-15 54.3 4.7 1.8 2 0 0 2 2 2 1 GATA zinc finger PAS_3 PF08447.12 KXG53149.1 - 3.7e-09 36.8 0.0 7.6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KXG53149.1 - 2.5e-06 27.5 0.0 2.2e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 KXG53149.1 - 0.00046 20.4 0.0 0.0016 18.6 0.0 2.1 1 1 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KXG53149.1 - 0.00072 19.8 0.0 0.0033 17.7 0.0 2.0 2 0 0 2 2 2 1 PAS domain DZR PF12773.7 KXG53149.1 - 0.15 12.1 0.7 0.32 11.0 0.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon L51_S25_CI-B8 PF05047.16 KXG53150.1 - 6.6e-20 70.8 0.0 1.3e-19 69.9 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DNA_pol3_theta PF06440.11 KXG53150.1 - 0.094 12.4 0.1 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase III, theta subunit tRNA-synt_1 PF00133.22 KXG53151.1 - 5.3e-38 130.7 0.0 2.1e-27 95.6 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KXG53151.1 - 8.1e-18 64.3 0.0 5.7e-11 41.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KXG53151.1 - 7.8e-17 61.6 0.1 2.2e-16 60.2 0.1 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KXG53151.1 - 1.7e-07 30.9 0.0 3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KXG53151.1 - 0.0036 16.3 0.0 0.13 11.2 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (K) Aminotran_1_2 PF00155.21 KXG53152.1 - 2e-38 132.5 0.0 2.9e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II MMR_HSR1 PF01926.23 KXG53152.1 - 1.2e-05 25.3 0.0 0.0024 18.0 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Beta_elim_lyase PF01212.21 KXG53152.1 - 0.00026 20.4 0.0 0.00047 19.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase RsgA_GTPase PF03193.16 KXG53152.1 - 0.016 15.1 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase ATPase-cat_bd PF12156.8 KXG53152.1 - 0.026 15.3 0.2 0.059 14.1 0.2 1.6 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Aminotran_3 PF00202.21 KXG53152.1 - 0.15 10.7 0.0 0.28 9.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III Sde2_N_Ubi PF13019.6 KXG53153.1 - 5.3e-68 228.0 0.9 8e-68 227.4 0.9 1.3 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Rotamase_2 PF13145.6 KXG53153.1 - 0.027 15.3 0.4 0.054 14.3 0.4 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain S10_plectin PF03501.15 KXG53154.1 - 8.3e-42 141.2 0.1 1.1e-41 140.8 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Rio2_N PF09202.11 KXG53154.1 - 0.047 13.9 0.4 0.078 13.2 0.1 1.6 2 0 0 2 2 2 0 Rio2, N-terminal TrmB PF01978.19 KXG53154.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Peptidase_M20 PF01546.28 KXG53155.1 - 6.7e-29 101.1 0.2 9.1e-29 100.6 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXG53155.1 - 3.9e-05 23.5 0.0 8.5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXG53155.1 - 0.0056 16.4 0.1 0.53 9.9 0.0 2.3 2 0 0 2 2 2 2 Peptidase family M28 APH PF01636.23 KXG53156.1 - 0.0023 17.9 0.0 0.0069 16.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1348 PF07080.11 KXG53156.1 - 0.084 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) Peptidase_C14 PF00656.22 KXG53157.1 - 6e-05 23.1 0.0 8.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Caspase domain COX7C PF02935.16 KXG53160.1 - 5.7 7.3 5.6 1.8 8.9 1.6 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc GET2 PF08690.10 KXG53161.1 - 0.02 14.6 0.1 0.034 13.8 0.1 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 ATG2_CAD PF13329.6 KXG53162.1 - 3.9e-46 156.6 0.0 1.4e-45 154.8 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KXG53162.1 - 1.3e-29 102.3 0.0 3.7e-29 100.9 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain A_deaminase PF00962.22 KXG53163.1 - 2.4e-23 83.0 0.0 3.7e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF2767 PF10965.8 KXG53163.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) MFS_1 PF07690.16 KXG53165.1 - 1.1e-16 60.7 51.6 2.4e-16 59.6 47.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG53165.1 - 5.6e-07 28.4 22.9 2.1e-06 26.5 22.9 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Retrotran_gag_2 PF14223.6 KXG53166.1 - 0.00011 21.8 0.0 0.00027 20.6 0.0 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Nucleos_tra2_C PF07662.13 KXG53167.1 - 5.6e-74 248.4 0.3 5.6e-74 248.4 0.3 3.1 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KXG53167.1 - 2.6e-22 79.2 3.8 2.6e-22 79.2 3.8 3.5 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus UQ_con PF00179.26 KXG53168.1 - 1.6e-47 160.7 0.0 2e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXG53168.1 - 0.00032 20.4 0.0 0.00059 19.5 0.0 1.5 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 KXG53168.1 - 0.00038 20.7 0.0 0.00051 20.3 0.0 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 KXG53168.1 - 0.00088 19.1 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.25 KXG53169.1 - 1.9e-59 201.2 0.0 2.4e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG53169.1 - 2.4e-24 86.0 0.0 3.3e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG53169.1 - 4e-08 32.9 0.0 5.4e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXG53169.1 - 0.0015 18.5 0.1 1.1 9.1 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXG53169.1 - 0.077 12.3 0.0 0.16 11.3 0.0 1.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 KXG53170.1 - 4e-06 26.6 0.0 8.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXG53170.1 - 5.1e-05 23.0 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXG53170.1 - 0.16 11.8 0.2 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 F-box DHBP_synthase PF00926.19 KXG53171.1 - 6.1e-80 267.3 0.1 7.2e-80 267.0 0.1 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase TFA2_Winged_2 PF18121.1 KXG53172.1 - 2.3e-23 81.6 0.4 6.2e-23 80.2 0.4 1.8 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KXG53172.1 - 2.3e-21 75.8 0.2 1.1e-20 73.6 0.0 2.2 2 1 0 2 2 2 1 TFIIE beta subunit core domain RNase_E_G PF10150.9 KXG53172.1 - 0.082 12.3 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease E/G family DUF3446 PF11928.8 KXG53172.1 - 0.18 12.1 3.5 0.35 11.2 3.5 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain TPR_MLP1_2 PF07926.12 KXG53173.1 - 3.3e-36 124.2 26.7 3.3e-36 124.2 26.7 17.3 9 6 7 16 16 16 8 TPR/MLP1/MLP2-like protein KASH_CCD PF14662.6 KXG53173.1 - 4.3e-05 23.4 28.5 4.3e-05 23.4 28.5 13.7 7 4 6 13 13 13 1 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 KXG53173.1 - 5.7e-05 23.2 19.5 5.7e-05 23.2 19.5 16.6 6 3 10 17 17 17 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Apolipoprotein PF01442.18 KXG53173.1 - 0.00013 21.9 35.9 0.00013 21.9 35.9 11.2 6 4 1 8 8 8 1 Apolipoprotein A1/A4/E domain APG6_N PF17675.1 KXG53173.1 - 0.0066 17.0 17.8 0.0066 17.0 17.8 18.2 5 3 11 17 17 17 4 Apg6 coiled-coil region ParE_toxin PF05016.15 KXG53173.1 - 0.12 12.9 0.0 0.12 12.9 0.0 6.1 5 0 0 5 5 5 0 ParE toxin of type II toxin-antitoxin system, parDE Scm3 PF10384.9 KXG53173.1 - 0.21 11.4 2.3 0.48 10.2 0.2 2.9 2 0 0 2 2 2 0 Centromere protein Scm3 Hexapep PF00132.24 KXG53174.1 - 8.1e-11 41.2 7.2 0.00068 19.3 3.0 3.8 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXG53174.1 - 0.00083 19.1 6.4 0.0033 17.1 1.7 3.0 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Acid_PPase PF12689.7 KXG53175.1 - 3.7e-70 235.1 0.0 4.4e-70 234.9 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase LRR_6 PF13516.6 KXG53177.1 - 0.0011 18.9 1.2 0.87 9.8 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich repeat Nuc_sug_transp PF04142.15 KXG53178.1 - 6.5e-77 258.8 0.9 9.6e-77 258.2 0.9 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter Sec63 PF02889.16 KXG53178.1 - 1.4e-37 129.3 0.1 2.5e-37 128.4 0.1 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KXG53178.1 - 1.2e-25 90.3 0.1 2e-25 89.6 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXG53178.1 - 1.4e-13 51.2 0.0 2.7e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXG53178.1 - 1.7e-07 31.5 0.0 8.2e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXG53178.1 - 0.00036 20.8 0.0 0.00088 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXG53178.1 - 0.0018 18.0 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXG53178.1 - 0.0038 17.6 0.0 0.0089 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KXG53178.1 - 0.024 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain UAA PF08449.11 KXG53178.1 - 0.055 12.7 4.7 0.15 11.3 3.4 1.9 1 1 1 2 2 2 0 UAA transporter family T2SSE PF00437.20 KXG53178.1 - 0.075 12.1 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TMEM234 PF10639.9 KXG53178.1 - 0.093 12.8 0.3 0.23 11.5 0.3 1.6 1 0 0 1 1 1 0 Putative transmembrane family 234 EmrE PF13536.6 KXG53178.1 - 0.22 11.1 3.3 0.22 11.1 0.1 2.1 2 0 0 2 2 2 0 Putative multidrug resistance efflux transporter TPT PF03151.16 KXG53178.1 - 0.5 9.7 7.9 0.64 9.3 1.3 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family Casc1 PF12366.8 KXG53179.1 - 0.017 14.7 0.7 0.042 13.4 0.0 1.8 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 HORMA PF02301.18 KXG53180.1 - 1.1e-47 162.3 0.0 1.7e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 HORMA domain WD40 PF00400.32 KXG53181.1 - 3.8e-41 138.3 19.0 9.8e-06 26.2 0.6 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.33 KXG53181.1 - 1.8e-08 34.1 0.2 6.1e-08 32.3 0.2 2.0 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXG53181.1 - 2e-08 34.0 0.2 3.9e-08 33.1 0.2 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KXG53181.1 - 2.2e-05 24.6 1.8 2.3 8.6 0.1 4.8 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KXG53181.1 - 0.0044 16.9 0.1 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 F-box Nup160 PF11715.8 KXG53181.1 - 0.074 11.7 7.4 5.6 5.5 0.2 5.0 3 1 2 6 6 6 0 Nucleoporin Nup120/160 CPSF_A PF03178.15 KXG53181.1 - 0.14 11.4 0.0 0.34 10.2 0.0 1.6 1 0 0 1 1 1 0 CPSF A subunit region MMR_HSR1 PF01926.23 KXG53182.1 - 7.8e-19 67.8 0.0 1.3e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXG53182.1 - 3.1e-06 27.3 0.0 0.00026 21.1 0.0 2.2 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KXG53182.1 - 8.8e-05 22.5 0.2 0.003 17.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KXG53182.1 - 0.00019 20.8 0.0 0.00027 20.3 0.0 1.1 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 KXG53182.1 - 0.00025 20.6 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KXG53182.1 - 0.0013 18.3 0.0 0.0086 15.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KXG53182.1 - 0.0024 17.3 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KXG53182.1 - 0.042 14.4 0.1 0.093 13.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KXG53182.1 - 0.046 13.5 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KXG53182.1 - 0.078 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Chromosome_seg PF13889.6 KXG53182.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Chromosome segregation during meiosis Clat_adaptor_s PF01217.20 KXG53183.1 - 1.2e-42 145.2 0.0 2.6e-42 144.1 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L7Ae PF01248.26 KXG53184.1 - 2.6e-23 81.6 0.7 4.1e-23 80.9 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3759 PF12585.8 KXG53185.1 - 3.2e-37 126.4 2.1 3.2e-37 126.4 2.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3759) CLASP_N PF12348.8 KXG53185.1 - 1.4e-07 31.3 0.1 1.7e-05 24.5 0.0 2.7 2 0 0 2 2 2 1 CLASP N terminal HEAT_2 PF13646.6 KXG53185.1 - 2.8e-06 27.6 1.3 1.4 9.4 0.0 4.5 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 KXG53185.1 - 3.4e-05 23.7 0.4 6.2 7.4 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 KXG53185.1 - 0.00073 19.6 0.1 0.04 14.0 0.0 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 TAN PF11640.8 KXG53185.1 - 0.001 19.2 2.3 0.0019 18.4 0.1 2.6 2 1 0 2 2 2 1 Telomere-length maintenance and DNA damage repair ERM PF00769.19 KXG53185.1 - 0.11 12.3 18.1 0.052 13.4 15.3 1.9 2 0 0 2 2 2 0 Ezrin/radixin/moesin family HIP1_clath_bdg PF16515.5 KXG53185.1 - 0.14 12.8 16.7 5.3 7.7 0.9 3.7 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Macoilin PF09726.9 KXG53185.1 - 1.9 6.9 8.0 0.058 11.9 1.9 1.5 2 0 0 2 2 2 0 Macoilin family PRKG1_interact PF15898.5 KXG53185.1 - 3.1 8.7 17.8 8.7 7.3 13.9 3.0 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Golgin_A5 PF09787.9 KXG53185.1 - 5 6.5 20.4 0.39 10.1 15.2 1.7 2 0 0 2 2 2 0 Golgin subfamily A member 5 V_ATPase_I PF01496.19 KXG53185.1 - 5.5 4.8 5.3 10 3.9 5.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COG5 PF10392.9 KXG53185.1 - 5.9 7.1 7.6 5.5 7.2 5.3 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Spc7 PF08317.11 KXG53185.1 - 7.8 5.3 17.1 1 8.2 10.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein WD40 PF00400.32 KXG53186.1 - 6.9e-52 172.3 21.1 2.3e-08 34.6 0.3 8.8 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG53186.1 - 4.2e-13 49.4 0.0 0.0057 16.9 0.1 4.8 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXG53186.1 - 1.3e-07 30.6 0.4 0.011 14.4 0.0 4.2 5 1 1 6 6 6 3 Nucleoporin Nup120/160 Ribosomal_S17 PF00366.20 KXG53187.1 - 2.7e-14 53.0 0.3 5.5e-14 52.0 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 NmrA PF05368.13 KXG53188.1 - 9.5e-16 58.1 0.0 1.3e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG53188.1 - 9.3e-14 51.7 0.1 1.6e-13 50.9 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXG53188.1 - 3.7e-06 27.2 0.0 7.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXG53188.1 - 4.3e-06 26.4 0.0 6.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.22 KXG53188.1 - 0.00078 20.3 0.0 0.0014 19.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 KXG53188.1 - 0.00083 19.5 0.5 0.0017 18.4 0.0 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KXG53188.1 - 0.0019 18.7 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KXG53188.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 KXG53188.1 - 0.016 15.1 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 KXG53188.1 - 0.034 13.2 0.0 0.07 12.1 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KXG53188.1 - 0.06 12.8 0.3 0.11 11.9 0.2 1.5 1 1 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KXG53188.1 - 0.062 12.4 0.1 0.089 11.9 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ApbA PF02558.16 KXG53188.1 - 0.065 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KXG53188.1 - 0.078 13.2 0.3 0.18 12.1 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain Zn_clus PF00172.18 KXG53189.1 - 1.6e-09 37.8 8.5 2.9e-09 36.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXG53189.1 - 7.3e-07 28.5 0.0 1.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glycophorin_A PF01102.18 KXG53190.1 - 0.00071 19.8 0.1 0.0014 18.8 0.1 1.4 1 0 0 1 1 1 1 Glycophorin A Podoplanin PF05808.11 KXG53190.1 - 0.0016 18.5 1.1 0.0028 17.8 1.1 1.4 1 0 0 1 1 1 1 Podoplanin Amnionless PF14828.6 KXG53190.1 - 0.022 13.6 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless TMEM154 PF15102.6 KXG53190.1 - 0.025 14.5 0.3 0.05 13.5 0.3 1.5 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.20 KXG53190.1 - 0.048 13.6 2.1 0.097 12.6 2.1 1.5 1 0 0 1 1 1 0 Syndecan domain PTP_tm PF18861.1 KXG53190.1 - 0.049 13.6 1.9 0.093 12.7 1.6 1.4 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J AJAP1_PANP_C PF15298.6 KXG53190.1 - 0.085 13.1 5.1 0.13 12.5 5.1 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus EphA2_TM PF14575.6 KXG53190.1 - 0.16 12.9 0.0 0.36 11.7 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Casein_kappa PF00997.18 KXG53190.1 - 0.52 10.4 7.7 0.76 9.9 7.7 1.2 1 0 0 1 1 1 0 Kappa casein CYYR1 PF10873.8 KXG53190.1 - 1.3 9.5 3.5 1.9 8.9 2.9 1.5 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 MGC-24 PF05283.11 KXG53190.1 - 3.7 8.0 12.1 11 6.5 12.1 1.8 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FSA_C PF10479.9 KXG53190.1 - 4.7 5.2 8.1 6.3 4.8 8.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Glyco_transf_20 PF00982.21 KXG53191.1 - 1e-200 667.4 0.0 1.2e-200 667.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 KXG53191.1 - 0.016 14.9 0.1 0.038 13.7 0.1 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain BLACT_WH PF17778.1 KXG53192.1 - 2.8e-18 65.6 0.0 5.1e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 KXG53192.1 - 2.6e-17 63.5 3.4 4.7e-15 56.1 3.1 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXG53192.1 - 3.1e-07 30.1 0.4 6.3e-07 29.1 0.4 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXG53192.1 - 0.00036 20.5 0.1 0.00057 19.8 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Aconitase PF00330.20 KXG53193.1 - 5.2e-151 503.8 0.0 6.5e-151 503.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXG53193.1 - 1.4e-43 148.4 0.0 2.4e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.8 KXG53194.1 - 1e-09 38.4 5.4 1.7e-09 37.7 5.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXG53194.1 - 0.00026 21.3 2.5 0.00046 20.5 2.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 KXG53194.1 - 0.00065 19.4 1.0 0.0011 18.6 1.0 1.4 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_4 PF13894.6 KXG53194.1 - 0.0015 19.2 0.9 0.0035 18.0 0.9 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXG53194.1 - 0.0074 16.3 1.9 0.012 15.6 1.9 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KXG53194.1 - 0.013 15.9 0.4 0.016 15.5 0.4 1.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 KXG53194.1 - 0.081 12.8 0.8 0.15 12.0 0.8 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.26 KXG53194.1 - 0.093 13.2 2.1 0.12 12.9 1.0 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Mito_carr PF00153.27 KXG53195.1 - 6.1e-49 163.9 0.8 1e-20 73.4 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_18 PF00704.28 KXG53195.1 - 0.14 11.8 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 adh_short PF00106.25 KXG53196.1 - 9.7e-25 87.2 0.2 1.4e-24 86.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG53196.1 - 3.4e-17 62.8 0.4 4.5e-17 62.4 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG53196.1 - 1.9e-06 27.9 0.1 3.2e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXG53196.1 - 1.2e-05 24.9 0.9 4e-05 23.2 0.9 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXG53196.1 - 0.0013 18.7 0.6 0.0016 18.3 0.6 1.4 1 1 0 1 1 1 1 NAD(P)H-binding SNF2_N PF00176.23 KXG53197.1 - 3.4e-55 187.2 0.0 5e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KXG53197.1 - 6.2e-55 186.2 0.6 3.6e-54 183.7 0.5 2.1 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 KXG53197.1 - 5.1e-15 55.8 0.0 1.3e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG53197.1 - 5e-07 29.9 0.0 1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXG53197.1 - 0.00068 18.9 0.0 0.0027 16.9 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Vac14_Fig4_bd PF11916.8 KXG53198.1 - 2.7e-80 268.3 8.0 2.7e-80 268.3 8.0 2.0 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KXG53198.1 - 2.4e-42 143.4 0.0 7.4e-40 135.5 0.0 3.9 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KXG53198.1 - 1.3e-07 31.9 1.2 0.028 15.0 0.0 4.9 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.22 KXG53198.1 - 1.3e-07 31.2 0.6 0.0011 19.0 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 KXG53198.1 - 0.00043 20.4 1.3 0.21 11.6 0.3 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXG53198.1 - 0.0021 18.4 3.8 2 8.9 0.0 4.7 5 1 1 6 6 6 2 HEAT repeats Arm PF00514.23 KXG53198.1 - 0.016 15.2 0.0 16 5.7 0.0 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Ank_2 PF12796.7 KXG53200.1 - 1e-76 253.5 0.0 7.8e-11 42.4 0.0 12.1 8 3 3 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG53200.1 - 3.4e-61 202.9 12.4 9e-10 38.9 0.2 14.3 12 2 4 16 16 16 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG53200.1 - 1.2e-41 135.9 15.2 0.00037 20.7 0.0 19.1 22 1 0 22 22 22 6 Ankyrin repeat Ank PF00023.30 KXG53200.1 - 1.6e-40 135.8 16.0 1e-05 25.7 0.1 17.3 19 0 0 19 19 19 7 Ankyrin repeat Ank_5 PF13857.6 KXG53200.1 - 1.1e-38 130.8 9.9 4.5e-06 26.8 0.2 12.3 11 1 2 13 13 13 8 Ankyrin repeats (many copies) NACHT PF05729.12 KXG53200.1 - 1.6e-07 31.4 0.5 1.7e-06 28.0 0.1 2.7 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 KXG53200.1 - 0.00017 22.0 0.0 0.00078 19.9 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KXG53200.1 - 0.00045 19.5 0.1 0.00088 18.5 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain Helo_like_N PF17111.5 KXG53200.1 - 0.036 13.4 0.3 0.084 12.2 0.3 1.6 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 KXG53200.1 - 0.081 13.2 0.0 0.4 11.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 KXG53201.1 - 2.5e-45 154.9 29.6 2.1e-36 125.6 25.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXG53201.1 - 4.2e-09 35.2 9.8 1.5e-08 33.4 5.1 2.9 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KXG53201.1 - 3.2e-05 23.0 25.7 0.024 13.5 16.6 3.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 KXG53201.1 - 5.5e-05 21.8 9.6 5.5e-05 21.8 9.6 2.0 2 1 0 2 2 2 1 Transmembrane secretion effector MFS_5 PF05631.14 KXG53201.1 - 0.0001 21.4 1.3 0.00025 20.1 0.7 2.0 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM EptA_B_N PF08019.12 KXG53201.1 - 0.013 15.4 0.2 0.013 15.4 0.2 2.2 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB PTR2 PF00854.21 KXG53201.1 - 0.013 14.3 13.5 0.25 10.1 0.6 3.1 2 1 0 2 2 2 0 POT family TauD PF02668.16 KXG53202.1 - 1.2e-16 61.4 0.2 1.7e-16 60.8 0.2 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXG53202.1 - 2.4e-06 26.9 0.0 4.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 CsiD Ank_4 PF13637.6 KXG53204.1 - 9.5e-18 64.3 0.6 0.00012 22.6 0.0 5.4 2 1 5 7 7 7 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXG53204.1 - 3e-17 63.0 0.1 5.5e-08 33.3 0.0 3.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG53204.1 - 4.2e-16 57.4 0.1 0.034 14.7 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KXG53204.1 - 1.3e-13 50.9 0.8 7.6e-05 22.9 0.0 4.5 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KXG53204.1 - 2.1e-11 43.7 1.3 0.04 14.4 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat DUF3632 PF12311.8 KXG53205.1 - 6.9e-14 52.7 6.2 9.8e-14 52.2 6.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) FMO-like PF00743.19 KXG53206.1 - 1.5e-29 102.8 0.0 5.9e-16 58.0 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXG53206.1 - 2.8e-13 49.8 0.1 2.4e-10 40.2 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG53206.1 - 2e-10 40.4 0.0 3.8e-09 36.2 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG53206.1 - 4e-09 36.1 0.0 5.9e-07 28.9 0.0 2.7 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXG53206.1 - 5.8e-06 26.4 2.1 0.00011 22.3 0.3 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXG53206.1 - 0.00012 22.2 0.1 0.00046 20.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXG53206.1 - 0.01 15.5 1.3 0.89 9.1 0.1 2.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KXG53206.1 - 0.02 14.1 0.3 0.14 11.4 0.1 2.0 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 KXG53206.1 - 0.13 12.4 0.1 4 7.5 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KXG53206.1 - 3.6 8.2 4.2 21 5.8 0.2 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KXG53207.1 - 1e-26 93.7 20.1 1.3e-26 93.4 20.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC_membrane PF00664.23 KXG53208.1 - 5.2e-39 134.6 12.1 7.2e-39 134.1 12.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXG53208.1 - 5.6e-34 117.6 0.0 1.1e-33 116.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KXG53208.1 - 4.5e-05 23.0 0.1 0.047 13.1 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXG53208.1 - 0.00021 21.7 0.0 0.00044 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXG53208.1 - 0.00053 20.3 0.1 0.0031 17.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KXG53208.1 - 0.0014 18.5 0.1 0.0085 15.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXG53208.1 - 0.01 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KXG53208.1 - 0.012 16.2 0.0 0.028 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXG53208.1 - 0.014 15.5 0.0 0.42 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KXG53208.1 - 0.016 14.8 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.15 KXG53208.1 - 0.02 14.8 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 KXG53208.1 - 0.021 15.3 0.0 0.17 12.3 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KXG53208.1 - 0.028 14.1 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KXG53208.1 - 0.053 13.4 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 KXG53208.1 - 0.058 13.1 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXG53208.1 - 0.071 13.1 0.0 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KXG53208.1 - 0.082 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KXG53208.1 - 0.2 11.4 1.4 17 5.1 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein SbcCD_C PF13558.6 KXG53208.1 - 0.47 10.7 2.1 4 7.7 0.6 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AIM24 PF01987.17 KXG53209.1 - 3.5e-46 157.6 0.0 4.3e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PQQ_2 PF13360.6 KXG53209.1 - 0.024 14.2 0.1 0.052 13.1 0.1 1.6 2 0 0 2 2 2 0 PQQ-like domain SLS PF14611.6 KXG53209.1 - 0.071 12.9 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Med9 PF07544.13 KXG53209.1 - 0.077 13.1 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.15 KXG53209.1 - 0.13 12.0 0.3 0.25 11.1 0.3 1.4 1 0 0 1 1 1 0 Septum formation initiator MFS_1 PF07690.16 KXG53210.1 - 6.5e-35 120.7 71.6 1.3e-25 90.1 38.5 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG53210.1 - 1e-07 31.2 29.4 6.9e-05 21.9 2.3 3.3 2 1 0 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.7 KXG53210.1 - 0.027 13.4 29.7 0.024 13.5 1.4 2.6 1 1 1 3 3 3 0 MFS_1 like family adh_short PF00106.25 KXG53211.1 - 2.5e-21 76.0 0.0 2.1e-20 73.0 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG53211.1 - 3.8e-14 52.8 0.0 3.7e-13 49.6 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG53211.1 - 3.8e-05 23.7 0.0 5.3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Kinesin PF00225.23 KXG53212.1 - 3.9e-80 269.3 0.9 3.9e-80 269.3 0.9 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXG53212.1 - 1e-21 77.4 0.0 2.7e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding HHH PF00633.23 KXG53212.1 - 0.00015 21.5 0.1 1 9.3 0.0 3.1 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_5 PF14520.6 KXG53212.1 - 0.0015 19.1 0.0 2.9 8.6 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix domain RlaP PF10127.9 KXG53212.1 - 0.049 13.2 2.2 0.087 12.4 0.9 1.9 2 0 0 2 2 2 0 RNA repair pathway DNA polymerase beta family HHH_3 PF12836.7 KXG53212.1 - 0.11 12.8 0.1 18 5.7 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif DDHD PF02862.17 KXG53212.1 - 0.45 10.6 2.4 0.8 9.8 0.5 2.2 2 0 0 2 2 2 0 DDHD domain Sec23_trunk PF04811.15 KXG53213.1 - 2.8e-72 243.2 0.0 5.2e-72 242.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KXG53213.1 - 1e-23 83.1 0.0 4.7e-23 81.0 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KXG53213.1 - 8.6e-17 61.7 0.0 1.9e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KXG53213.1 - 1.5e-16 60.2 4.7 2.5e-16 59.4 4.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXG53213.1 - 2.8e-11 43.1 0.0 5.9e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KXG53213.1 - 0.018 14.4 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain UBA_4 PF14555.6 KXG53214.1 - 0.0042 16.9 0.2 0.0079 16.0 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain Pkinase PF00069.25 KXG53215.1 - 1.5e-68 231.0 0.0 1.8e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG53215.1 - 3.6e-32 111.7 0.0 4.8e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXG53215.1 - 0.00018 20.9 0.2 0.00028 20.3 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXG53215.1 - 0.0046 15.9 0.1 0.0069 15.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXG53215.1 - 0.013 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KXG53215.1 - 0.035 14.0 0.3 0.088 12.7 0.3 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KXG53215.1 - 0.092 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HEM4 PF02602.15 KXG53216.1 - 7.1e-41 140.1 0.0 8.3e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD NmrA PF05368.13 KXG53217.1 - 2.7e-16 59.9 0.0 3.3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXG53217.1 - 1.2e-14 54.3 0.1 3.6e-14 52.8 0.1 1.8 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXG53217.1 - 9.7e-14 51.7 0.0 1.4e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXG53217.1 - 4.4e-11 42.3 0.1 9.2e-11 41.3 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXG53217.1 - 2.6e-08 33.6 0.3 2.1e-07 30.6 0.1 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXG53217.1 - 3.3e-07 29.7 0.0 5.3e-06 25.8 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXG53217.1 - 5.2e-05 22.5 0.3 0.0095 15.1 0.1 2.7 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.25 KXG53217.1 - 0.00013 21.5 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG53217.1 - 0.0033 17.0 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF4838 PF16126.5 KXG53217.1 - 0.0053 16.2 0.0 3 7.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4838) KR PF08659.10 KXG53217.1 - 0.05 13.5 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 KR domain DDE_Tnp_1_3 PF13612.6 KXG53217.1 - 0.16 12.0 0.0 0.5 10.4 0.0 1.8 2 0 0 2 2 2 0 Transposase DDE domain HIT PF01230.23 KXG53218.1 - 5.4e-18 65.5 0.1 9.3e-13 48.8 0.1 2.2 2 0 0 2 2 2 2 HIT domain DcpS_C PF11969.8 KXG53218.1 - 2.4e-08 34.4 0.0 1.2e-06 28.9 0.0 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CRAL_TRIO PF00650.20 KXG53219.1 - 2.6e-43 147.5 0.0 5.1e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXG53219.1 - 1.6e-14 53.8 0.3 4.9e-14 52.2 0.3 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXG53219.1 - 3.1e-06 27.4 0.0 5.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DASH_Dam1 PF08653.10 KXG53220.1 - 1.8e-29 101.3 2.3 2.5e-29 100.8 2.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 UCH PF00443.29 KXG53221.1 - 1.8e-46 158.8 0.5 2.3e-46 158.4 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXG53221.1 - 8.4e-16 58.4 3.2 8.4e-15 55.2 3.2 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KXG53221.1 - 0.0014 18.9 0.9 0.0014 18.9 0.9 3.2 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Ytp1 PF10355.9 KXG53222.1 - 1.4e-115 385.2 8.2 1.4e-115 385.2 8.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KXG53222.1 - 7e-31 106.1 15.5 4.7e-29 100.3 7.9 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) DLH PF01738.18 KXG53223.1 - 1.8e-31 109.4 0.0 2e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXG53223.1 - 0.0078 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Rhomboid PF01694.22 KXG53224.1 - 4.2e-17 62.5 8.1 4.2e-17 62.5 8.1 1.6 2 0 0 2 2 2 1 Rhomboid family Gaa1 PF04114.14 KXG53225.1 - 6.6e-177 589.5 0.8 8.9e-177 589.0 0.8 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component LysM PF01476.20 KXG53226.1 - 0.0094 16.0 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 LysM domain Chitin_bind_1 PF00187.19 KXG53226.1 - 0.013 16.0 9.0 0.013 16.0 9.0 2.5 2 1 0 2 2 2 0 Chitin recognition protein Dicty_REP PF05086.12 KXG53226.1 - 0.57 8.1 4.2 0.71 7.8 4.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RNA_pol_Rpc4 PF05132.14 KXG53226.1 - 1.3 9.4 7.4 2.1 8.8 7.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Ndc1_Nup PF09531.10 KXG53226.1 - 4.6 5.8 7.0 6.2 5.4 7.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PCI PF01399.27 KXG53227.1 - 9.1e-10 39.0 0.0 1.9e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KXG53227.1 - 0.00011 21.7 0.7 0.00023 20.7 0.7 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix Dimerisation2 PF16864.5 KXG53227.1 - 0.19 11.7 2.0 0.36 10.8 0.0 2.5 3 0 0 3 3 3 0 Dimerisation domain CN_hydrolase PF00795.22 KXG53228.1 - 1.6e-59 201.3 0.0 2e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_L31e PF01198.19 KXG53228.1 - 5e-39 132.4 0.9 7.5e-39 131.8 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.18 KXG53228.1 - 0.059 12.9 0.1 0.15 11.6 0.1 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel Phage_holin_2_4 PF16082.5 KXG53229.1 - 0.1 12.3 1.1 0.23 11.2 1.1 1.7 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Ran_BP1 PF00638.18 KXG53230.1 - 7.5e-11 42.4 0.0 1.4e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 KXG53230.1 - 4.6e-05 24.0 0.9 4.6e-05 24.0 0.9 7.9 9 2 0 9 9 9 1 NUP50 (Nucleoporin 50 kDa) Pectate_lyase_3 PF12708.7 KXG53231.1 - 1.2e-97 326.0 21.5 7.8e-85 284.1 10.1 2.8 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KXG53231.1 - 1.9e-09 37.0 2.2 0.00026 20.6 0.1 2.5 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Helicase_C PF00271.31 KXG53232.1 - 2.2e-06 28.0 0.0 3.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXG53232.1 - 3.9e-05 23.0 0.0 5.8e-05 22.4 0.0 1.3 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase adh_short_C2 PF13561.6 KXG53233.1 - 3.5e-60 203.5 1.0 4.7e-60 203.0 0.3 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG53233.1 - 5.2e-40 137.0 0.2 8.9e-40 136.2 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Cyclase PF04199.13 KXG53233.1 - 2.9e-16 60.0 0.0 5.7e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Putative cyclase KR PF08659.10 KXG53233.1 - 8.6e-12 45.3 0.1 1.8e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 KR domain GxGYxYP_N PF16216.5 KXG53233.1 - 0.022 14.9 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal Mrr_cat PF04471.12 KXG53233.1 - 0.099 12.7 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Restriction endonuclease adh_short_C2 PF13561.6 KXG53234.1 - 2.2e-54 184.5 0.0 2.7e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG53234.1 - 2.2e-42 144.7 0.0 3.1e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG53234.1 - 1.1e-12 48.2 0.0 1.5e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXG53234.1 - 0.00025 20.6 0.1 0.054 12.9 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXG53234.1 - 0.00095 18.7 0.0 0.011 15.3 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXG53234.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.19 KXG53234.1 - 0.083 11.9 0.0 0.11 11.5 0.0 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glu_dehyd_C PF16912.5 KXG53234.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus MFS_1 PF07690.16 KXG53235.1 - 3.7e-27 95.2 22.4 3.7e-27 95.2 22.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily SLATT_1 PF18181.1 KXG53235.1 - 0.064 13.2 0.0 0.34 10.9 0.0 2.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 ATP_synt_H PF05493.13 KXG53235.1 - 1.2 9.7 6.4 14 6.2 0.0 3.8 4 0 0 4 4 4 0 ATP synthase subunit H Corona_M PF01635.18 KXG53235.1 - 1.3 8.3 5.6 0.32 10.3 2.0 1.8 2 0 0 2 2 2 0 Coronavirus M matrix/glycoprotein Aa_trans PF01490.18 KXG53236.1 - 2e-38 132.2 33.4 2.3e-38 132.0 33.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ABC_tran PF00005.27 KXG53237.1 - 1.2e-46 158.6 0.0 7.1e-29 101.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXG53237.1 - 1.1e-32 113.8 22.5 1.6e-21 77.2 8.8 3.4 3 1 1 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 KXG53237.1 - 4.3e-13 49.2 4.6 1.6e-06 27.7 1.9 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXG53237.1 - 9e-09 35.6 0.0 0.13 12.0 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXG53237.1 - 6.6e-07 29.7 0.2 0.076 13.3 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXG53237.1 - 1.2e-06 28.1 2.2 0.0025 17.5 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KXG53237.1 - 9.6e-06 26.2 1.4 0.084 13.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXG53237.1 - 2e-05 25.0 2.1 0.072 13.5 0.5 3.5 3 1 0 3 3 2 2 AAA ATPase domain AAA_25 PF13481.6 KXG53237.1 - 7.6e-05 22.4 0.5 0.013 15.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KXG53237.1 - 0.00017 20.7 0.6 0.39 9.7 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KXG53237.1 - 0.00033 20.6 0.1 0.52 10.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXG53237.1 - 0.0012 18.9 0.2 0.57 10.3 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 KXG53237.1 - 0.0016 18.6 1.8 0.0081 16.3 0.4 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 KXG53237.1 - 0.0019 18.0 0.1 2.8 7.6 0.0 2.6 2 1 0 2 2 2 2 AAA domain cobW PF02492.19 KXG53237.1 - 0.002 17.7 0.9 0.1 12.2 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KXG53237.1 - 0.004 17.1 5.4 0.76 9.7 0.1 3.4 4 0 0 4 4 3 2 NACHT domain AAA_15 PF13175.6 KXG53237.1 - 0.0079 15.9 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KXG53237.1 - 0.0081 15.5 1.0 0.56 9.5 0.2 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.12 KXG53237.1 - 0.013 14.8 0.3 0.65 9.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 KXG53237.1 - 0.013 15.6 0.9 4.1 7.6 0.5 3.1 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 KXG53237.1 - 0.014 14.3 1.9 0.25 10.2 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 KXG53237.1 - 0.017 15.1 0.1 0.47 10.5 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 KXG53237.1 - 0.017 14.9 0.0 12 5.5 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KXG53237.1 - 0.031 14.2 0.6 10 6.0 0.1 2.7 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.7 KXG53237.1 - 0.036 13.6 0.2 8.4 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Pox_A32 PF04665.12 KXG53237.1 - 0.064 12.7 1.6 6.9 6.1 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ABC_ATPase PF09818.9 KXG53237.1 - 0.068 11.9 1.4 1.6 7.5 0.0 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_18 PF13238.6 KXG53237.1 - 0.085 13.4 0.0 22 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KXG53237.1 - 0.089 12.1 0.9 0.86 8.9 0.0 2.3 2 0 0 2 2 2 0 KaiC Dynamin_N PF00350.23 KXG53237.1 - 0.1 12.6 2.2 3.2 7.8 0.0 2.8 3 0 0 3 3 2 0 Dynamin family DUF2075 PF09848.9 KXG53237.1 - 0.1 11.8 0.7 3.4 6.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_13 PF13166.6 KXG53237.1 - 0.18 10.4 0.5 0.83 8.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXG53237.1 - 0.21 12.0 0.1 9.4 6.7 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_5 PF07728.14 KXG53237.1 - 0.26 11.3 1.1 1.7 8.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SWI2_SNF2 PF18766.1 KXG53237.1 - 0.32 10.6 1.0 2.1 7.9 0.0 2.4 2 1 0 2 2 2 0 SWI2/SNF2 ATPase MobB PF03205.14 KXG53237.1 - 0.32 10.9 0.9 18 5.2 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 KXG53237.1 - 0.58 9.9 3.5 19 5.0 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein SCP2 PF02036.17 KXG53238.1 - 2e-26 92.4 0.6 2.5e-26 92.1 0.6 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KXG53238.1 - 5.8e-06 26.6 0.1 7.2e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KXG53238.1 - 0.012 16.0 0.0 0.015 15.7 0.0 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain F-box-like PF12937.7 KXG53239.1 - 0.074 13.0 1.5 0.23 11.4 0.1 2.3 2 0 0 2 2 2 0 F-box-like SNF2_N PF00176.23 KXG53240.1 - 5e-65 219.5 0.1 8.5e-65 218.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXG53240.1 - 1.2e-16 61.0 0.0 3e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KXG53240.1 - 2.1e-08 33.8 3.4 4.7e-08 32.7 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXG53240.1 - 6.1e-07 29.2 5.0 1.5e-06 27.9 5.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KXG53240.1 - 2.7e-06 27.5 0.1 8.4e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 KXG53240.1 - 1.7e-05 24.7 2.0 3.6e-05 23.7 2.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXG53240.1 - 7.9e-05 22.4 5.0 0.00015 21.5 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXG53240.1 - 0.00014 22.1 4.7 0.00034 20.9 4.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KXG53240.1 - 0.00022 21.3 1.9 0.00049 20.2 1.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXG53240.1 - 0.0094 15.8 5.3 0.043 13.7 5.7 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KXG53240.1 - 0.025 14.4 4.5 0.083 12.7 4.5 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 KXG53240.1 - 0.14 12.1 6.3 0.55 10.2 6.6 1.9 1 1 0 1 1 1 0 zinc-RING finger domain DZR PF12773.7 KXG53240.1 - 0.24 11.4 1.3 0.65 10.1 1.3 1.7 1 1 0 1 1 1 0 Double zinc ribbon Ras PF00071.22 KXG53241.1 - 4.3e-49 166.2 0.0 5.1e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXG53241.1 - 3e-29 101.7 0.1 7.6e-29 100.4 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG53241.1 - 1.3e-10 41.0 0.0 1.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 KXG53241.1 - 0.00063 20.1 0.1 0.005 17.2 0.1 2.1 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 KXG53241.1 - 0.00069 19.7 0.0 0.0015 18.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXG53241.1 - 0.0016 17.9 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KXG53241.1 - 0.014 14.6 1.9 1.1 8.3 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit AAA_24 PF13479.6 KXG53241.1 - 0.015 15.0 0.1 0.021 14.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 KXG53241.1 - 0.017 14.6 0.1 0.031 13.7 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 KXG53241.1 - 0.029 13.9 0.1 0.046 13.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KXG53241.1 - 0.078 13.3 0.1 0.13 12.6 0.0 1.5 2 0 0 2 2 1 0 AAA ATPase domain ArgoMid PF16487.5 KXG53241.1 - 0.083 13.2 0.0 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 Mid domain of argonaute RsgA_GTPase PF03193.16 KXG53241.1 - 0.095 12.6 0.1 8.9 6.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 KXG53241.1 - 0.11 12.5 0.1 0.25 11.4 0.2 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 KXG53241.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KXG53241.1 - 0.12 11.6 0.4 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_33 PF13671.6 KXG53241.1 - 0.22 11.7 0.2 0.22 11.7 0.2 1.6 2 0 0 2 2 1 0 AAA domain Nas2_N PF18265.1 KXG53242.1 - 1.4e-29 101.8 0.1 2e-29 101.3 0.1 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KXG53242.1 - 2.4e-11 43.3 0.2 4.5e-11 42.4 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KXG53242.1 - 2.3e-09 37.5 0.3 5.1e-09 36.3 0.3 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KXG53242.1 - 8.5e-07 29.4 0.0 1.5e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 KXG53242.1 - 1.3e-05 25.4 0.1 2.2e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 PDZ domain DUF4944 PF16302.5 KXG53242.1 - 0.042 13.9 0.2 8.6 6.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4944) RhoGEF PF00621.20 KXG53243.1 - 1.1e-21 77.9 2.8 1e-20 74.8 2.8 2.1 1 1 0 1 1 1 1 RhoGEF domain Peptidase_S64 PF08192.11 KXG53243.1 - 0.18 10.2 4.6 0.34 9.3 4.5 1.5 1 1 0 1 1 1 0 Peptidase family S64 SBDS PF01172.18 KXG53244.1 - 1.4e-24 85.9 0.0 1.7e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Phage_TAC_5 PF08890.11 KXG53244.1 - 0.12 12.3 0.0 0.25 11.4 0.0 1.5 2 0 0 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC UDG PF03167.19 KXG53245.1 - 3.5e-20 72.6 0.0 6e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Ndc1_Nup PF09531.10 KXG53245.1 - 4.3 5.9 7.9 7.2 5.2 7.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NAD_binding_6 PF08030.12 KXG53246.1 - 3.5e-22 79.2 0.0 5.9e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXG53246.1 - 3.5e-20 72.1 0.0 7.7e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KXG53246.1 - 2.5e-19 69.6 10.2 2.5e-19 69.6 10.2 1.9 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 KXG53246.1 - 0.0065 16.8 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF3165 PF11364.8 KXG53247.1 - 0.15 12.5 2.3 0.45 10.9 2.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) Methyltransf_2 PF00891.18 KXG53248.1 - 1.5e-19 70.1 0.0 2.2e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KXG53248.1 - 8.2e-05 22.5 0.4 0.00022 21.2 0.4 1.8 1 0 0 1 1 1 1 Dimerisation domain APH PF01636.23 KXG53249.1 - 3.9e-08 33.5 0.8 1e-07 32.2 0.0 2.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family F-box-like PF12937.7 KXG53251.1 - 8.8e-06 25.5 0.2 3.1e-05 23.8 0.2 2.0 1 0 0 1 1 1 1 F-box-like Bac_luciferase PF00296.20 KXG53252.1 - 6.9e-60 203.1 0.3 9.1e-60 202.7 0.3 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase NRDE-2 PF08424.10 KXG53253.1 - 3e-85 286.2 1.3 7.7e-85 284.8 0.1 2.1 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KXG53253.1 - 0.044 14.6 12.6 7.6 7.6 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat BP28CT PF08146.12 KXG53254.1 - 3e-42 144.1 1.7 3.6e-41 140.7 0.9 2.6 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KXG53254.1 - 1.4e-26 93.1 2.6 1.1e-25 90.3 0.3 3.8 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 KXG53254.1 - 7.4e-09 35.9 3.9 0.1 13.0 0.0 6.5 6 1 1 7 7 7 4 HEAT repeats HEAT PF02985.22 KXG53254.1 - 1.2e-05 25.1 3.7 1.1 9.8 0.0 7.4 8 0 0 8 8 8 1 HEAT repeat DUF3385 PF11865.8 KXG53254.1 - 0.0048 16.8 0.1 3.8 7.4 0.0 3.9 3 1 0 3 3 3 1 Domain of unknown function (DUF3385) CARD PF00619.21 KXG53254.1 - 0.019 15.0 2.2 0.046 13.7 0.2 2.8 3 0 0 3 3 3 0 Caspase recruitment domain DUF5525 PF17663.1 KXG53254.1 - 0.047 11.8 0.0 0.072 11.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) HEAT_EZ PF13513.6 KXG53254.1 - 0.069 13.7 13.8 10 6.8 0.0 7.8 7 2 2 9 9 9 0 HEAT-like repeat Bac_luciferase PF00296.20 KXG53255.1 - 2.1e-47 162.1 0.7 2.6e-45 155.2 0.7 2.0 1 1 0 1 1 1 1 Luciferase-like monooxygenase SSF PF00474.17 KXG53256.1 - 1.3e-22 80.3 27.5 1.3e-22 80.3 27.5 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family Phage_holin_6_1 PF09682.10 KXG53256.1 - 4.5 7.7 6.8 0.27 11.7 0.6 2.2 3 0 0 3 3 3 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Glyco_hydro_18 PF00704.28 KXG53257.1 - 6.3e-85 285.6 2.1 7.3e-85 285.4 2.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AP_endonuc_2 PF01261.24 KXG53257.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel EthD PF07110.11 KXG53258.1 - 1.5e-18 67.7 1.3 1.8e-18 67.5 1.3 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KXG53258.1 - 0.0038 17.7 0.0 0.007 16.8 0.0 1.4 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Arrestin_N PF00339.29 KXG53259.1 - 8.4e-07 29.1 0.0 3e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_N PF04425.12 KXG53259.1 - 3.6e-06 26.0 1.8 9.3e-05 21.4 0.1 2.2 1 1 1 2 2 2 2 Bul1 N terminus Bul1_C PF04426.12 KXG53259.1 - 0.00063 19.2 0.0 0.00098 18.6 0.0 1.2 1 0 0 1 1 1 1 Bul1 C terminus MMS1_N PF10433.9 KXG53260.1 - 5.8e-155 516.6 0.0 8e-155 516.2 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KXG53260.1 - 8.2e-101 337.5 0.0 6.5e-100 334.6 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 KXG53260.1 - 0.019 15.3 0.0 0.29 11.5 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ubiquitin PF00240.23 KXG53261.1 - 2.4e-20 72.1 0.1 3.5e-20 71.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXG53261.1 - 7.3e-08 32.1 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 KXG53261.1 - 2.1e-07 30.7 0.2 2.1e-07 30.7 0.2 2.1 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 KXG53261.1 - 2.6e-05 24.3 0.0 4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KXG53261.1 - 2.7e-05 24.7 0.1 5.7e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain YukD PF08817.10 KXG53261.1 - 0.00044 20.9 0.0 0.00097 19.8 0.0 1.6 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.6 KXG53261.1 - 0.062 13.8 0.1 0.18 12.3 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain GerD PF17898.1 KXG53261.1 - 0.089 12.7 4.2 0.16 11.9 3.4 1.8 1 1 0 1 1 1 0 Spore germination GerD central core domain STI1 PF17830.1 KXG53261.1 - 0.91 9.5 21.4 1.3 9.0 2.8 3.5 2 1 1 3 3 3 0 STI1 domain XPC-binding PF09280.11 KXG53261.1 - 2.7 7.8 13.9 5.2 6.9 5.5 3.6 2 1 1 3 3 3 0 XPC-binding domain DUF2477 PF10631.9 KXG53261.1 - 6.8 7.4 12.3 0.069 13.8 1.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2477) EMP70 PF02990.16 KXG53262.1 - 1.8e-200 667.0 0.0 2.3e-200 666.7 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Sulfatase PF00884.23 KXG53264.1 - 4.3e-60 203.7 0.2 7.1e-60 203.0 0.2 1.4 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KXG53264.1 - 8.1e-23 80.0 0.1 1.7e-22 79.0 0.1 1.6 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 KXG53264.1 - 1.3e-08 34.8 0.1 7e-07 29.1 0.1 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 KXG53264.1 - 0.0019 18.9 0.3 0.023 15.4 0.3 2.3 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 KXG53264.1 - 0.0033 16.1 0.0 0.0044 15.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 KXG53264.1 - 0.0042 17.3 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF1501 PF07394.12 KXG53264.1 - 0.0079 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Metalloenzyme PF01676.18 KXG53264.1 - 0.077 12.4 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 Metalloenzyme superfamily CN_hydrolase PF00795.22 KXG53266.1 - 1.1e-29 103.6 0.0 5.7e-29 101.2 0.0 2.1 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Pyridoxal_deC PF00282.19 KXG53269.1 - 1.2e-79 267.8 0.0 1.7e-79 267.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain AMP-binding PF00501.28 KXG53270.1 - 7.6e-39 133.5 0.0 1.1e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KXG53270.1 - 1e-07 31.8 0.7 2.1e-07 30.8 0.7 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus RFamide_26RFa PF11109.8 KXG53271.1 - 0.65 10.5 4.0 2.2 8.8 4.0 1.9 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 PALP PF00291.25 KXG53273.1 - 1.3e-42 146.3 1.4 1.7e-42 145.9 1.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SBDS_C PF09377.10 KXG53274.1 - 1.4e-42 144.3 0.0 2.5e-42 143.5 0.0 1.4 1 1 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KXG53274.1 - 2.3e-31 107.7 0.0 4.5e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein AP3D1 PF06375.11 KXG53274.1 - 0.14 12.4 6.0 0.17 12.1 4.0 1.9 1 1 1 2 2 2 0 AP-3 complex subunit delta-1 Ribosomal_S13 PF00416.22 KXG53275.1 - 1.4e-56 190.4 3.0 1.7e-56 190.1 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF1822 PF08852.11 KXG53275.1 - 0.0062 15.6 0.0 0.008 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1822) FbpA PF05833.11 KXG53275.1 - 0.016 14.0 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 KXG53275.1 - 0.034 14.4 0.1 0.11 12.8 0.1 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix motif DUF2746 PF10874.8 KXG53275.1 - 0.081 13.4 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) peroxidase PF00141.23 KXG53277.1 - 8.8e-44 149.9 0.0 1.3e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF4003 PF13170.6 KXG53277.1 - 0.095 12.1 0.0 0.21 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) Iso_dh PF00180.20 KXG53278.1 - 8.9e-106 353.9 0.0 1.1e-105 353.6 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4686 PF15742.5 KXG53278.1 - 0.015 14.5 1.4 0.024 13.8 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Lebercilin PF15619.6 KXG53278.1 - 0.046 13.4 1.9 0.078 12.6 1.9 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.8 KXG53278.1 - 0.051 13.7 1.5 0.1 12.7 1.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 KXG53278.1 - 0.14 11.0 2.0 0.23 10.3 2.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TEX13 PF15186.6 KXG53278.1 - 0.42 10.3 5.2 0.85 9.3 5.2 1.5 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family TPR_2 PF07719.17 KXG53279.1 - 1.9e-06 27.6 6.3 0.12 12.6 0.4 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXG53279.1 - 4.1e-05 23.2 8.0 0.023 14.5 1.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG53279.1 - 0.024 14.8 1.5 0.052 13.8 1.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.9 KXG53279.1 - 0.041 12.6 0.3 0.061 12.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_8 PF13181.6 KXG53279.1 - 1.8 9.0 10.9 5.2 7.5 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_10 PF00331.20 KXG53280.1 - 2.3e-101 339.1 0.0 2.6e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KXG53280.1 - 7.2e-12 45.1 10.8 7.2e-12 45.1 10.8 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain Ribonuclease PF00545.20 KXG53280.1 - 0.019 15.7 0.0 0.053 14.3 0.0 1.7 1 0 0 1 1 1 0 ribonuclease Glyco_hydro_1 PF00232.18 KXG53280.1 - 0.07 11.5 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 DUF2841 PF11001.8 KXG53281.1 - 7.6e-44 148.7 0.7 1.1e-43 148.2 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) SSXT PF05030.12 KXG53282.1 - 1.2e-07 31.2 0.0 0.021 14.4 0.0 2.4 2 0 0 2 2 2 2 SSXT protein (N-terminal region) DUF108 PF01958.18 KXG53282.1 - 0.058 13.8 1.6 0.12 12.8 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF108 Elf4 PF07011.11 KXG53282.1 - 0.12 12.3 0.1 18 5.3 0.0 2.6 3 0 0 3 3 3 0 Early Flowering 4 domain PDZ_1 PF12812.7 KXG53283.1 - 1.5e-51 172.3 0.0 7.3e-34 115.6 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KXG53283.1 - 1.7e-24 87.5 1.5 2.6e-21 77.1 0.1 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 KXG53283.1 - 3.6e-16 58.8 0.2 6.2e-08 32.4 0.2 4.6 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 KXG53283.1 - 2.4e-10 40.6 0.1 0.0001 22.5 0.0 4.4 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 KXG53283.1 - 2.6e-05 24.5 0.0 0.023 15.0 0.0 3.6 3 0 0 3 3 3 1 PDZ domain Tricorn_PDZ PF14685.6 KXG53283.1 - 0.0035 17.3 0.3 1.7 8.7 0.1 3.4 3 0 0 3 3 3 1 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 KXG53283.1 - 0.0049 16.5 0.0 0.017 14.8 0.0 2.0 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Peptidase_S46 PF10459.9 KXG53283.1 - 0.21 10.2 0.0 0.38 9.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase S46 INCENP_ARK-bind PF03941.15 KXG53284.1 - 3.2e-16 59.0 2.1 2e-15 56.5 2.1 2.6 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region PTR2 PF00854.21 KXG53286.1 - 2.1e-61 208.0 5.9 3.7e-61 207.1 5.9 1.3 1 1 0 1 1 1 1 POT family Reticulon PF02453.17 KXG53287.1 - 3.9e-26 91.9 3.8 5.1e-26 91.5 3.8 1.1 1 0 0 1 1 1 1 Reticulon BRX_N PF13713.6 KXG53287.1 - 0.044 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain DNA_topoisoIV PF00521.20 KXG53289.1 - 3.3e-135 451.3 0.0 6e-135 450.4 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KXG53289.1 - 3.9e-53 179.1 3.6 2.2e-52 176.7 2.6 2.6 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KXG53289.1 - 2.1e-24 86.0 0.3 5.6e-24 84.6 0.3 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KXG53289.1 - 4.1e-16 59.5 0.1 1.3e-15 57.9 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KXG53289.1 - 1.7e-06 28.2 0.0 7e-06 26.2 0.0 2.1 1 0 0 1 1 1 1 Toprim domain RabGAP-TBC PF00566.18 KXG53290.1 - 1.8e-49 168.3 0.0 8.7e-49 166.1 0.0 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Phage_GP20 PF06810.11 KXG53290.1 - 0.35 10.7 0.0 0.35 10.7 0.0 3.3 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF1512 PF07431.12 KXG53290.1 - 0.53 9.2 1.1 0.97 8.4 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) XhlA PF10779.9 KXG53290.1 - 3.1 8.1 4.2 51 4.2 0.2 3.6 3 0 0 3 3 3 0 Haemolysin XhlA YabA PF06156.13 KXG53290.1 - 3.7 8.2 12.1 1.8 9.2 0.1 3.3 3 0 0 3 3 3 0 Initiation control protein YabA DUF3405 PF11885.8 KXG53291.1 - 1.1e-160 535.7 2.6 1.4e-160 535.3 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Polysacc_syn_2C PF08485.10 KXG53292.1 - 0.48 10.2 0.1 0.48 10.2 0.1 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal adh_short_C2 PF13561.6 KXG53293.1 - 4.1e-58 196.7 3.7 4.9e-58 196.5 3.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG53293.1 - 2.1e-46 157.9 3.9 2.7e-46 157.5 3.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG53293.1 - 1.4e-12 47.9 3.8 2.1e-12 47.3 3.8 1.2 1 0 0 1 1 1 1 KR domain YAcAr PF10686.9 KXG53293.1 - 0.008 16.1 1.4 0.056 13.4 1.1 2.3 1 1 1 2 2 2 1 YspA, cpYpsA-related SLOG family Pyr_redox_2 PF07992.14 KXG53293.1 - 0.012 14.8 0.6 0.018 14.3 0.6 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.19 KXG53293.1 - 0.036 13.4 1.8 1.3 8.3 0.3 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KXG53293.1 - 0.05 13.0 1.4 0.074 12.5 1.3 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Mur_ligase PF01225.25 KXG53293.1 - 0.052 13.9 1.6 0.13 12.6 1.2 1.8 2 0 0 2 2 2 0 Mur ligase family, catalytic domain Kri1 PF05178.12 KXG53293.1 - 0.098 13.2 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 KRI1-like family ATP-synt_F PF01990.17 KXG53293.1 - 0.1 12.9 0.6 2.1 8.7 0.8 2.6 2 1 0 2 2 2 0 ATP synthase (F/14-kDa) subunit 3HCDH_N PF02737.18 KXG53293.1 - 0.11 12.4 2.2 0.17 11.8 2.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_92 PF07971.12 KXG53294.1 - 1.9e-151 505.1 0.6 2.5e-151 504.8 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXG53294.1 - 9.8e-69 231.9 0.8 1.8e-68 231.0 0.8 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Zn_clus PF00172.18 KXG53295.1 - 2.3e-08 34.0 12.1 3.8e-08 33.3 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXG53296.1 - 1.2e-25 90.2 37.0 3.7e-24 85.3 35.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KXG53297.1 - 5.2e-27 94.7 14.3 5.2e-27 94.7 14.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG53297.1 - 1.3e-12 47.4 0.1 1.3e-12 47.4 0.1 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXG53297.1 - 3.8e-05 22.3 1.6 3.8e-05 22.3 1.6 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Med4 PF10018.9 KXG53298.1 - 2.2e-50 171.0 0.2 3.6e-50 170.4 0.2 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 YL1 PF05764.13 KXG53298.1 - 0.11 12.5 2.2 0.14 12.3 0.7 1.8 1 1 1 2 2 2 0 YL1 nuclear protein HsbA PF12296.8 KXG53298.1 - 0.6 10.5 6.6 0.086 13.3 2.1 1.9 2 0 0 2 2 2 0 Hydrophobic surface binding protein A DUF2786 PF10979.8 KXG53298.1 - 1.4 8.9 8.4 3.5 7.6 4.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) SnoaL PF07366.12 KXG53299.1 - 6.6e-06 25.9 0.1 1.1e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXG53299.1 - 3.8e-05 24.3 0.2 7.5e-05 23.3 0.2 1.5 1 0 0 1 1 1 1 SnoaL-like domain Nuc_N PF14448.6 KXG53299.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Nuclease N terminal COesterase PF00135.28 KXG53300.1 - 2.8e-74 250.8 0.0 3.6e-74 250.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG53300.1 - 6.4e-08 32.7 0.2 3.3e-07 30.4 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXG53300.1 - 0.0014 17.5 0.0 0.0086 15.0 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KXG53300.1 - 0.16 11.4 1.4 0.27 10.7 1.4 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Glyco_hydro2_C5 PF18565.1 KXG53301.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 Amidase PF01425.21 KXG53302.1 - 6.4e-42 144.1 0.0 4.1e-26 92.0 0.0 2.0 1 1 1 2 2 2 2 Amidase Beta-lactamase PF00144.24 KXG53303.1 - 1.3e-49 169.3 0.2 1.7e-49 168.9 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KXG53303.1 - 3.4e-18 66.0 0.0 6.3e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) CFEM PF05730.11 KXG53304.1 - 2.1e-11 43.7 11.0 3.5e-11 43.0 11.0 1.4 1 0 0 1 1 1 1 CFEM domain Mito_carr PF00153.27 KXG53305.1 - 7.6e-59 195.7 4.6 3.4e-19 68.5 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 KXG53305.1 - 3.6 7.8 5.3 0.71 10.0 0.2 2.4 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif UQ_con PF00179.26 KXG53307.1 - 5.2e-44 149.3 0.0 5.9e-44 149.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXG53307.1 - 0.15 12.3 0.5 0.21 11.9 0.5 1.4 1 1 0 1 1 1 0 RWD domain RTA1 PF04479.13 KXG53308.1 - 6.6e-72 241.5 7.0 8.6e-72 241.1 7.0 1.1 1 0 0 1 1 1 1 RTA1 like protein DctQ PF04290.12 KXG53308.1 - 0.0039 17.1 1.8 0.0039 17.1 1.8 2.7 2 1 1 3 3 3 1 Tripartite ATP-independent periplasmic transporters, DctQ component PhrC_PhrF PF11131.8 KXG53308.1 - 6.9 6.3 7.6 0.31 10.6 0.4 2.5 3 0 0 3 3 3 0 Rap-phr extracellular signalling Fungal_trans_2 PF11951.8 KXG53309.1 - 0.0022 16.8 0.1 0.0033 16.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_4 PF07993.12 KXG53310.1 - 9.6e-39 133.1 0.0 1.2e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KXG53310.1 - 3.8e-05 23.0 0.0 5.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXG53310.1 - 0.00038 20.0 0.0 0.00074 19.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Cation_efflux PF01545.21 KXG53311.1 - 4.3e-46 157.2 13.2 4.3e-46 157.2 13.2 3.4 3 1 0 3 3 3 1 Cation efflux family Glyco_trans_1_4 PF13692.6 KXG53312.1 - 1.8e-09 38.1 0.0 3.8e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXG53312.1 - 5.9e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KXG53312.1 - 8e-05 22.2 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KXG53312.1 - 0.016 15.6 0.0 0.029 14.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 RMI1_N PF08585.12 KXG53312.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 RecQ mediated genome instability protein Thiolase_N PF00108.23 KXG53313.1 - 2e-89 299.4 0.6 3.2e-89 298.7 0.6 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXG53313.1 - 2.4e-38 130.5 1.2 6.8e-38 129.1 1.2 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain zf-TFIIIC PF12660.7 KXG53313.1 - 1.1e-30 105.6 0.8 2.3e-30 104.5 0.8 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.7 KXG53313.1 - 2.3e-21 76.6 0.0 4.6e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term ketoacyl-synt PF00109.26 KXG53313.1 - 9.8e-06 25.3 0.5 2.5e-05 24.0 0.5 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain UQ_con PF00179.26 KXG53314.1 - 1e-51 174.3 0.0 1.1e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXG53314.1 - 0.0019 17.9 0.0 0.0022 17.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXG53314.1 - 0.087 13.1 0.0 0.18 12.1 0.0 1.5 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.23 KXG53315.1 - 2.2e-111 372.0 0.0 5.4e-111 370.7 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXG53315.1 - 2.3e-25 89.3 0.0 9.5e-25 87.3 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding Fez1 PF06818.15 KXG53315.1 - 0.0078 16.7 12.5 0.0078 16.7 12.5 4.0 3 1 1 4 4 4 1 Fez1 STPPase_N PF16891.5 KXG53315.1 - 0.026 15.0 1.8 8.4 6.9 0.1 3.1 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain DUF1398 PF07166.11 KXG53315.1 - 0.042 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) ATG_C PF09333.11 KXG53315.1 - 0.1 12.9 0.2 0.97 9.8 0.2 2.7 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain DUF5633 PF18656.1 KXG53315.1 - 1.4 8.9 4.7 0.46 10.4 0.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5633) CALCOCO1 PF07888.11 KXG53315.1 - 2.3 7.0 59.2 1.8 7.3 35.3 2.3 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like XkdW PF09636.10 KXG53315.1 - 9.4 6.4 11.5 4.1 7.6 0.3 3.6 3 0 0 3 3 3 0 XkdW protein Filament PF00038.21 KXG53315.1 - 9.5 5.7 61.9 10 5.6 14.8 4.3 2 1 1 3 3 3 0 Intermediate filament protein EF-hand_1 PF00036.32 KXG53316.1 - 5.7e-26 88.1 11.2 4e-08 32.3 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KXG53316.1 - 3e-25 86.0 5.5 3.9e-06 26.4 0.1 5.2 4 1 1 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 KXG53316.1 - 3.1e-24 85.2 7.9 1e-15 57.9 0.9 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KXG53316.1 - 8.5e-17 59.8 12.3 0.00017 20.9 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 KXG53316.1 - 1e-15 57.3 11.2 5.4e-06 26.2 1.1 4.1 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KXG53316.1 - 7.3e-09 35.5 6.5 0.0028 17.6 0.2 3.9 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KXG53316.1 - 0.00018 21.8 0.7 0.025 14.9 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain EF-hand_10 PF14788.6 KXG53316.1 - 0.0022 17.8 1.0 0.52 10.2 0.1 3.5 3 1 0 3 3 3 1 EF hand DUF1679 PF07914.11 KXG53316.1 - 0.02 13.8 0.3 1.5 7.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) SPARC_Ca_bdg PF10591.9 KXG53316.1 - 0.022 15.1 1.7 2.3 8.5 0.3 3.2 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EMP70 PF02990.16 KXG53317.1 - 3.2e-205 682.7 0.3 4.2e-205 682.3 0.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Sas10_Utp3 PF04000.15 KXG53318.1 - 8.8e-18 64.7 0.5 8.8e-18 64.7 0.5 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family GOLD_2 PF13897.6 KXG53318.1 - 0.14 12.7 3.6 2.5 8.6 2.0 2.4 1 1 1 2 2 2 0 Golgi-dynamics membrane-trafficking eIF-3c_N PF05470.12 KXG53318.1 - 2.5 6.3 7.9 0.46 8.7 4.3 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DNA_pol_phi PF04931.13 KXG53318.1 - 6 4.8 10.8 1.4 6.9 7.3 1.6 2 0 0 2 2 2 0 DNA polymerase phi HEXIM PF15313.6 KXG53318.1 - 7.1 6.8 12.8 19 5.4 5.8 2.9 3 0 0 3 3 3 0 Hexamethylene bis-acetamide-inducible protein PepSY_TM PF03929.16 KXG53319.1 - 1.3 8.6 4.6 1.4 8.5 3.6 1.3 1 1 0 1 1 1 0 PepSY-associated TM region FMO-like PF00743.19 KXG53320.1 - 1.2e-23 83.3 0.0 3e-23 82.0 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXG53320.1 - 1.9e-15 56.9 0.0 6e-12 45.4 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG53320.1 - 7.5e-13 48.4 0.3 7.8e-10 38.5 0.2 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG53320.1 - 3.3e-12 46.2 0.1 2e-09 37.1 0.0 3.2 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXG53320.1 - 3.3e-07 30.4 0.4 1.6e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXG53320.1 - 7.1e-07 29.7 1.7 0.031 14.8 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG53320.1 - 2.4e-05 24.1 0.6 0.00053 19.7 0.1 2.8 3 1 1 4 4 4 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXG53320.1 - 2.7e-05 23.6 0.0 0.017 14.5 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KXG53320.1 - 3.3e-05 23.9 0.5 0.028 14.4 0.0 3.4 4 0 0 4 4 3 1 FAD-NAD(P)-binding 3HCDH_N PF02737.18 KXG53320.1 - 0.00027 20.9 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXG53320.1 - 0.0018 18.3 0.0 3.3 7.8 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KXG53320.1 - 0.0021 17.2 0.5 0.003 16.7 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 KXG53320.1 - 0.0029 18.0 0.0 0.15 12.5 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 KXG53320.1 - 0.0062 15.3 0.9 0.13 10.9 0.1 2.7 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 KXG53320.1 - 0.0071 15.5 0.5 0.015 14.4 0.2 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 KXG53320.1 - 0.025 14.0 0.0 0.91 8.9 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KXG53320.1 - 0.14 11.5 0.1 0.33 10.3 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXG53320.1 - 0.27 10.5 0.1 0.27 10.5 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 KXG53321.1 - 1.1e-22 80.8 0.0 3.4e-22 79.2 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG53321.1 - 0.0027 17.0 1.2 0.043 13.0 1.2 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG53321.1 - 0.0029 16.9 0.9 1.9 7.7 0.2 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG53321.1 - 0.023 15.3 0.2 0.21 12.1 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXG53321.1 - 0.024 13.3 0.1 2.3 6.9 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein SE PF08491.10 KXG53321.1 - 0.028 13.5 0.0 0.089 11.8 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.14 KXG53321.1 - 0.045 12.6 2.5 1.3 7.7 0.3 2.2 1 1 1 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 KXG53321.1 - 0.089 11.8 0.0 4.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Fungal_trans PF04082.18 KXG53322.1 - 1.2e-05 24.6 0.3 1.6e-05 24.1 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AXE1 PF05448.12 KXG53323.1 - 2.6e-15 55.9 0.2 4.8e-09 35.3 0.1 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 KXG53323.1 - 7.6e-15 54.8 0.0 5.5e-14 52.0 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXG53323.1 - 4.2e-14 53.7 0.1 5.3e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG53323.1 - 3e-12 46.7 0.0 7.8e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KXG53323.1 - 2.3e-08 34.0 0.0 4.2e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KXG53323.1 - 2.6e-08 33.7 0.0 3e-06 27.0 0.0 3.0 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KXG53323.1 - 9.2e-07 28.5 0.0 0.003 17.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.11 KXG53323.1 - 7.4e-06 26.0 0.0 5.6e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1100 PF06500.11 KXG53323.1 - 1.2e-05 24.4 0.0 9.5e-05 21.4 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) GFA PF04828.14 KXG53324.1 - 1.9e-22 79.4 0.0 2.5e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme GST_C PF00043.25 KXG53325.1 - 2.7e-15 56.3 0.0 4.1e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXG53325.1 - 3.7e-14 52.9 0.0 6.4e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXG53325.1 - 4.3e-14 52.6 0.1 7.5e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXG53325.1 - 1.9e-12 47.2 0.0 3.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXG53325.1 - 3.6e-10 40.0 0.1 9.2e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXG53325.1 - 1.8e-05 24.6 0.0 3.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXG53325.1 - 0.069 13.7 0.0 0.55 10.8 0.0 2.0 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Plant_NMP1 PF06694.11 KXG53325.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) ADH_zinc_N PF00107.26 KXG53326.1 - 7.3e-26 90.7 0.2 1.2e-25 89.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG53326.1 - 4.2e-19 69.9 0.0 8e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG53326.1 - 1.1e-10 41.4 0.1 3.9e-10 39.6 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KXG53326.1 - 0.0029 17.8 0.0 0.0054 17.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NMO PF03060.15 KXG53326.1 - 0.025 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase AlaDh_PNT_C PF01262.21 KXG53326.1 - 0.026 13.8 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SusD-like PF12741.7 KXG53327.1 - 0.23 10.3 0.0 0.31 9.9 0.0 1.1 1 0 0 1 1 1 0 Susd and RagB outer membrane lipoprotein GST_N_2 PF13409.6 KXG53328.1 - 3e-16 59.5 0.0 4.9e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXG53328.1 - 3.3e-09 36.6 1.0 2.4e-08 33.9 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXG53328.1 - 0.00073 19.7 0.0 0.0024 18.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXG53328.1 - 0.0012 19.0 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4455 PF14643.6 KXG53328.1 - 0.31 9.6 0.0 0.44 9.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) GFA PF04828.14 KXG53329.1 - 2e-24 85.8 0.2 2.7e-24 85.3 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme FAD_binding_4 PF01565.23 KXG53331.1 - 5.4e-05 22.9 0.1 8.3e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain 5_nucleotid_C PF02872.18 KXG53332.1 - 3.2e-36 124.9 0.0 5.6e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KXG53332.1 - 3.4e-06 27.7 1.3 4.4e-06 27.3 0.3 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase His_Phos_1 PF00300.22 KXG53332.1 - 0.0028 17.4 2.6 9.7 5.8 0.0 4.1 3 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) DUF2169 PF09937.9 KXG53332.1 - 0.011 15.2 0.2 0.04 13.4 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2169) HTH_21 PF13276.6 KXG53332.1 - 0.047 13.8 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 HTH-like domain AflR PF08493.10 KXG53334.1 - 1.8e-31 109.7 7.3 2.4e-31 109.3 7.3 1.2 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 KXG53334.1 - 9.2e-08 32.1 12.9 2.1e-07 31.0 12.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GalP_UDP_transf PF01087.22 KXG53334.1 - 0.16 12.4 0.1 0.3 11.5 0.1 1.4 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain Tweety PF04906.13 KXG53335.1 - 0.052 12.2 0.2 0.09 11.4 0.2 1.3 1 0 0 1 1 1 0 Tweety NUC173 PF08161.12 KXG53335.1 - 0.081 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 NUC173 domain AMP-binding PF00501.28 KXG53336.1 - 4.5e-49 167.2 0.0 5.7e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KXG53337.1 - 1e-74 251.3 0.2 2.9e-74 249.9 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KXG53337.1 - 6.2e-50 170.2 4.2 2.1e-49 168.5 0.1 2.9 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KXG53337.1 - 1.5e-43 149.5 0.2 1.4e-42 146.3 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXG53337.1 - 3.5e-35 120.6 2.3 3.5e-35 120.6 2.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KXG53337.1 - 2e-11 43.7 0.0 4.6e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KXG53337.1 - 3.7e-11 43.2 0.2 9.7e-11 41.9 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KXG53337.1 - 8.8e-07 29.4 0.0 2.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KXG53337.1 - 2.4e-05 23.8 0.4 0.00011 21.7 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Lactamase_B PF00753.27 KXG53338.1 - 1.2e-14 54.8 6.0 5.3e-13 49.4 6.0 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXG53338.1 - 1.3e-05 24.8 0.6 3.5e-05 23.4 0.6 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXG53338.1 - 0.0027 17.6 0.1 0.0047 16.8 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 KXG53338.1 - 0.008 16.1 0.1 0.063 13.3 0.2 2.5 3 1 0 3 3 3 1 Beta-lactamase associated winged helix domain DUF1772 PF08592.11 KXG53339.1 - 2.4e-26 92.7 6.6 2.4e-26 92.7 6.6 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) EthD PF07110.11 KXG53339.1 - 3.2e-08 34.6 0.8 0.00023 22.2 0.1 2.6 2 1 1 3 3 3 2 EthD domain MmlI PF09448.10 KXG53339.1 - 0.092 13.2 0.1 0.18 12.2 0.1 1.3 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase NAD_binding_10 PF13460.6 KXG53340.1 - 1.7e-19 70.4 0.0 2e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXG53340.1 - 1.2e-07 31.6 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KXG53340.1 - 7.5e-05 23.2 0.0 0.00014 22.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KXG53340.1 - 0.0019 17.7 0.0 0.0039 16.7 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXG53340.1 - 0.032 14.2 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 KXG53340.1 - 0.034 13.2 0.0 0.045 12.8 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXG53340.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Questin_oxidase PF14027.6 KXG53341.1 - 1.9e-72 244.7 0.1 2.2e-72 244.5 0.1 1.0 1 0 0 1 1 1 1 Questin oxidase-like GMC_oxred_N PF00732.19 KXG53342.1 - 6.6e-51 173.4 0.0 9e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG53342.1 - 2e-33 116.0 0.0 3.4e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXG53342.1 - 0.00011 21.4 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXG53342.1 - 0.00015 21.1 0.0 0.00072 18.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG53342.1 - 0.00071 19.8 0.0 0.0022 18.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXG53342.1 - 0.00082 18.7 0.0 0.026 13.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG53342.1 - 0.0023 17.2 0.0 0.0042 16.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KXG53342.1 - 0.015 14.9 0.0 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KXG53342.1 - 0.015 14.1 0.0 0.024 13.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KXG53342.1 - 0.025 13.8 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 KXG53342.1 - 0.041 13.0 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KXG53342.1 - 0.15 12.0 0.1 0.44 10.5 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KXG53342.1 - 0.18 12.1 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Cu-oxidase_3 PF07732.15 KXG53343.1 - 1.1e-41 141.5 5.3 3.2e-41 140.1 3.4 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXG53343.1 - 2.2e-41 140.8 4.7 6e-35 119.9 0.0 4.0 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 KXG53343.1 - 8.4e-29 100.7 0.3 6.7e-28 97.8 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase Methyltransf_25 PF13649.6 KXG53344.1 - 4.8e-10 40.0 0.0 9.6e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG53344.1 - 1.6e-07 31.9 0.0 2.6e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG53344.1 - 1.4e-06 28.1 0.0 3.9e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG53344.1 - 6.1e-06 26.9 0.0 1.1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG53344.1 - 0.012 15.4 0.0 0.026 14.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KXG53344.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXG53344.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Aldo_ket_red PF00248.21 KXG53345.1 - 3.4e-65 220.1 0.0 3.9e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FMN_dh PF01070.18 KXG53346.1 - 5.4e-110 367.7 0.0 6.2e-110 367.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXG53346.1 - 2.6e-05 23.6 0.0 3.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXG53346.1 - 0.0028 16.7 0.2 0.0091 15.0 0.1 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXG53346.1 - 0.018 14.5 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase Hydantoinase_B PF02538.14 KXG53347.1 - 3.2e-217 722.0 0.1 4.1e-217 721.7 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXG53347.1 - 1e-101 340.0 0.1 5.1e-100 334.5 0.0 2.2 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXG53347.1 - 1.6e-58 197.4 0.0 1.6e-55 187.6 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Fungal_trans PF04082.18 KXG53348.1 - 1.9e-20 73.0 0.0 3.1e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyclase PF04199.13 KXG53349.1 - 1.2e-14 54.7 0.0 3.4e-14 53.2 0.0 1.6 1 1 1 2 2 2 1 Putative cyclase ADH_N_2 PF16884.5 KXG53349.1 - 0.021 14.7 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Chitin_synth_1 PF01644.17 KXG53350.1 - 3.3e-67 225.5 0.0 4.8e-67 225.0 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KXG53350.1 - 8.8e-28 96.1 0.1 2.6e-27 94.6 0.1 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KXG53350.1 - 4e-22 78.5 0.2 2.3e-19 69.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXG53350.1 - 8.6e-10 38.9 0.1 8.6e-10 38.9 0.1 2.9 3 1 0 3 3 3 1 Glycosyl transferase family group 2 adh_short PF00106.25 KXG53351.1 - 1.7e-30 106.0 0.0 2.2e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG53351.1 - 4.5e-23 82.0 0.0 6.3e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG53351.1 - 0.00026 21.0 0.0 0.001 19.0 0.0 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXG53351.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG53351.1 - 0.018 14.4 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXG53351.1 - 0.069 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ULD PF16534.5 KXG53351.1 - 0.15 12.1 0.1 0.42 10.7 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-like oligomerisation domain of SATB MFS_1 PF07690.16 KXG53352.1 - 4.7e-37 127.7 42.0 4.7e-37 127.7 42.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DHDPS PF00701.22 KXG53353.1 - 2.1e-40 138.2 0.0 2.5e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family TPR_10 PF13374.6 KXG53353.1 - 0.071 13.0 0.5 3 7.8 0.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 KXG53354.1 - 1.1e-67 228.8 0.0 1.2e-67 228.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aa_trans PF01490.18 KXG53355.1 - 1.2e-48 165.9 38.4 1.3e-48 165.7 38.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_76 PF03663.14 KXG53357.1 - 2.1e-139 465.2 21.9 3.1e-139 464.6 21.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 HATPase_c PF02518.26 KXG53357.1 - 1e-26 93.6 0.0 1.4e-25 89.9 0.0 2.8 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXG53357.1 - 4.3e-25 88.1 0.6 8.1e-25 87.2 0.6 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXG53357.1 - 2e-14 53.4 0.0 5.3e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KXG53357.1 - 0.0002 21.7 1.7 0.14 12.6 0.0 3.1 3 0 0 3 3 3 2 HAMP domain dCache_1 PF02743.18 KXG53357.1 - 0.00044 20.1 2.3 0.0014 18.4 2.3 1.8 1 1 0 1 1 1 1 Cache domain Aminotran_4 PF01063.19 KXG53358.1 - 7.8e-44 150.2 0.0 9.3e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DAO PF01266.24 KXG53359.1 - 1.2e-30 107.3 4.2 2.1e-30 106.5 4.2 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXG53359.1 - 0.00021 20.6 0.6 0.0013 18.0 0.2 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KXG53359.1 - 0.00054 19.3 0.2 0.00054 19.3 0.2 2.7 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG53359.1 - 0.00092 19.4 0.8 0.00092 19.4 0.8 2.2 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXG53359.1 - 0.0015 17.7 2.0 0.0022 17.2 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KXG53359.1 - 0.12 11.6 0.4 0.2 10.8 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KXG53359.1 - 1.7 7.6 4.7 0.29 10.2 0.4 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A BNR_2 PF13088.6 KXG53360.1 - 2.4e-21 76.3 0.1 1.2e-13 51.0 0.0 2.1 2 0 0 2 2 2 2 BNR repeat-like domain BNR PF02012.20 KXG53360.1 - 1.1e-11 42.9 22.0 0.029 14.3 0.2 6.3 6 0 0 6 6 6 5 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KXG53360.1 - 8.7e-05 21.5 10.2 0.00022 20.1 0.1 3.9 3 1 0 4 4 4 1 Sortilin, neurotensin receptor 3, CHB_HEX_C PF03174.13 KXG53360.1 - 0.0019 18.2 5.0 2.1 8.4 0.0 4.9 4 1 1 5 5 5 1 Chitobiase/beta-hexosaminidase C-terminal domain Mo-co_dimer PF03404.16 KXG53360.1 - 0.26 11.3 5.0 19 5.3 0.1 4.5 3 1 1 5 5 5 0 Mo-co oxidoreductase dimerisation domain DHDPS PF00701.22 KXG53361.1 - 1.1e-42 145.8 0.0 1.3e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans_2 PF11951.8 KXG53362.1 - 4.2e-10 39.0 0.3 1.2e-09 37.4 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG53362.1 - 1.8e-07 31.2 11.8 3.5e-07 30.2 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HK PF02110.15 KXG53362.1 - 0.12 11.7 0.3 0.28 10.6 0.2 1.6 1 1 0 1 1 1 0 Hydroxyethylthiazole kinase family Aldo_ket_red PF00248.21 KXG53363.1 - 2.5e-63 214.0 0.0 3e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 KXG53364.1 - 2.1e-33 115.7 29.4 2.1e-33 115.7 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PgaD PF13994.6 KXG53364.1 - 0.16 12.1 2.5 2.2 8.3 0.3 3.0 3 0 0 3 3 3 0 PgaD-like protein Laminin_G_1 PF00054.23 KXG53365.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain Transferase PF02458.15 KXG53366.1 - 2.2e-13 49.7 0.0 2.7e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Transferase family Kinesin PF00225.23 KXG53368.1 - 2.8e-40 138.3 0.0 4e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Peptidase_M24 PF00557.24 KXG53369.1 - 1.3e-41 142.6 0.0 1.7e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Fungal_trans PF04082.18 KXG53370.1 - 3e-08 33.0 0.0 5.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TauD PF02668.16 KXG53371.1 - 1.5e-28 100.4 0.1 2.4e-28 99.7 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LssY_C PF14067.6 KXG53371.1 - 0.12 11.9 0.4 12 5.4 0.0 2.7 3 0 0 3 3 3 0 LssY C-terminus CIA30 PF08547.12 KXG53371.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) RVT_1 PF00078.27 KXG53372.1 - 0.0024 17.4 0.0 0.0057 16.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Uteroglobin PF01099.17 KXG53372.1 - 0.013 15.8 4.3 2.5 8.5 0.0 4.8 5 0 0 5 5 5 0 Uteroglobin family Form_Nir_trans PF01226.17 KXG53373.1 - 1.8e-57 194.4 25.9 8.4e-38 130.0 8.8 2.0 1 1 1 2 2 2 2 Formate/nitrite transporter DUF2107 PF09880.9 KXG53373.1 - 0.044 13.9 0.9 7.7 6.7 0.1 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2107) MFS_1 PF07690.16 KXG53374.1 - 3.9e-34 118.1 26.5 3.7e-33 114.9 26.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3094 PF11293.8 KXG53374.1 - 0.062 13.0 0.2 0.51 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) AMP-binding PF00501.28 KXG53375.1 - 3e-78 263.3 0.3 6e-78 262.3 0.2 1.6 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KXG53375.1 - 1.8e-74 250.5 0.0 4.7e-74 249.1 0.0 1.8 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 KXG53375.1 - 2.5e-66 224.2 0.0 3.9e-66 223.6 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 KXG53375.1 - 1.3e-53 182.2 0.0 2.1e-53 181.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KXG53375.1 - 7.3e-51 172.6 0.0 1.2e-49 168.6 0.0 2.4 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KXG53375.1 - 1.3e-42 146.4 0.0 3e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KXG53375.1 - 1.3e-33 116.2 0.0 6.4e-33 114.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 KXG53375.1 - 4.1e-30 104.2 0.0 9.4e-30 103.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KXG53375.1 - 1.4e-18 67.0 2.8 2.8e-09 37.2 0.1 4.3 5 0 0 5 5 4 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KXG53375.1 - 1.7e-14 54.4 0.0 4.1e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXG53375.1 - 3.3e-13 49.5 0.0 6.7e-12 45.3 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KXG53375.1 - 1.5e-12 48.1 0.0 5.6e-12 46.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG53375.1 - 2.3e-12 47.0 0.0 8.8e-12 45.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG53375.1 - 2.5e-12 46.8 0.0 7.1e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KXG53375.1 - 2.8e-12 46.6 0.0 3.1e-11 43.2 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 KXG53375.1 - 8.8e-11 42.3 0.0 2.8e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 KXG53375.1 - 1.2e-10 41.9 0.0 3.9e-10 40.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KXG53375.1 - 1.5e-05 24.5 0.0 3.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KXG53375.1 - 2.7e-05 23.6 0.0 5.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 KXG53375.1 - 2.8e-05 23.8 0.0 5.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) 3Beta_HSD PF01073.19 KXG53375.1 - 4.3e-05 22.7 0.0 0.00019 20.6 0.0 2.0 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.9 KXG53375.1 - 0.0021 17.8 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase NAD_binding_10 PF13460.6 KXG53375.1 - 0.0075 16.2 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H-binding DUF728 PF05304.12 KXG53375.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF728) ADH_zinc_N PF00107.26 KXG53376.1 - 7.3e-11 42.2 0.0 1.4e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG53376.1 - 0.0012 19.9 0.0 0.0088 17.1 0.0 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase p450 PF00067.22 KXG53379.1 - 3.2e-52 177.8 0.0 4.9e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Acyl-CoA_dh_1 PF00441.24 KXG53380.1 - 8.3e-34 117.0 0.9 1.3e-33 116.4 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXG53380.1 - 2.5e-18 66.1 0.1 3.8e-18 65.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXG53380.1 - 9.3e-12 45.4 0.0 1.9e-11 44.4 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KXG53380.1 - 0.00071 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal PH_BEACH PF14844.6 KXG53380.1 - 0.13 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH AA_permease PF00324.21 KXG53381.1 - 1.5e-129 432.7 50.6 1.8e-129 432.4 50.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG53381.1 - 9.2e-32 110.4 54.3 1.1e-31 110.1 54.3 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 KXG53382.1 - 2.4e-16 59.6 48.6 2.4e-16 59.6 48.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily VIT1 PF01988.19 KXG53382.1 - 0.032 14.1 1.0 0.032 14.1 1.0 3.4 4 1 0 4 4 4 0 VIT family Phosphoesterase PF04185.14 KXG53384.1 - 1.3e-79 268.0 2.6 1.7e-79 267.6 2.6 1.1 1 0 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.23 KXG53384.1 - 0.0044 16.5 0.3 4.7 6.5 0.0 3.0 3 0 0 3 3 3 3 Sulfatase NinF PF05810.12 KXG53384.1 - 0.0059 16.4 0.2 0.016 15.1 0.2 1.7 1 0 0 1 1 1 1 NinF protein Transketolase_N PF00456.21 KXG53385.1 - 2.1e-112 375.4 0.1 3e-111 371.6 0.1 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KXG53385.1 - 2.8e-42 144.4 0.1 4.9e-42 143.6 0.1 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXG53385.1 - 2.3e-07 30.7 0.0 5.8e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain ADH_N PF08240.12 KXG53386.1 - 3.3e-29 101.0 1.0 7.4e-29 99.8 1.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG53386.1 - 8.2e-15 54.9 0.0 1.5e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXG53386.1 - 3.5e-06 26.7 0.9 4.5e-05 23.0 0.9 2.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 KXG53386.1 - 0.035 13.3 0.0 0.98 8.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXG53386.1 - 0.036 13.4 2.3 0.042 13.1 0.1 2.0 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans_2 PF11951.8 KXG53388.1 - 3.2e-16 59.1 5.9 1.4e-15 57.0 5.9 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KXG53388.1 - 0.0037 16.3 0.0 0.0078 15.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MIT PF04212.18 KXG53388.1 - 0.46 10.6 0.0 0.46 10.6 0.0 2.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Pyr_redox_3 PF13738.6 KXG53389.1 - 8.2e-05 22.0 0.0 0.027 13.7 0.0 2.7 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXG53389.1 - 0.00038 19.0 0.2 0.024 13.1 0.0 2.8 4 0 0 4 4 4 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXG53389.1 - 0.00058 19.2 0.0 0.065 12.5 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG53389.1 - 0.00086 18.5 0.0 0.0035 16.6 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXG53389.1 - 0.022 15.0 0.1 5.8 7.2 0.1 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Amidohydro_1 PF01979.20 KXG53390.1 - 2.4e-27 96.2 0.0 4.3e-27 95.3 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXG53390.1 - 4.3e-11 42.9 0.1 2.8e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Ank_2 PF12796.7 KXG53391.1 - 2.8e-36 124.0 10.9 1.9e-09 38.0 0.1 4.3 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG53391.1 - 1.2e-22 77.5 3.7 0.00026 21.2 0.0 7.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 KXG53391.1 - 9.5e-20 70.7 4.6 2.7e-08 34.2 0.1 6.0 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KXG53391.1 - 6.9e-17 61.1 11.3 0.00039 20.7 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KXG53391.1 - 1.1e-12 47.9 2.1 0.00036 20.8 0.1 4.7 1 1 3 5 5 5 5 Ankyrin repeats (many copies) NACHT PF05729.12 KXG53391.1 - 2.2e-08 34.2 0.2 8.2e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 KXG53391.1 - 0.00063 19.0 0.0 0.0024 17.1 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 KXG53391.1 - 0.0023 17.9 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KXG53391.1 - 0.0028 18.1 0.1 0.012 16.0 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KXG53391.1 - 0.0087 16.3 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXG53391.1 - 0.029 14.4 0.1 2.2 8.3 0.1 2.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KXG53391.1 - 0.084 13.3 0.0 0.26 11.7 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DAO PF01266.24 KXG53392.1 - 1.3e-38 133.5 0.0 2e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG53392.1 - 2.3e-07 30.9 0.0 7.4e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG53392.1 - 6.7e-05 22.3 0.0 0.04 13.2 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG53392.1 - 9.1e-05 21.8 0.0 0.00063 19.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXG53392.1 - 0.00022 20.1 0.0 0.092 11.4 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Shikimate_DH PF01488.20 KXG53392.1 - 0.0018 18.4 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KXG53392.1 - 0.0089 16.6 0.0 0.063 13.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG53392.1 - 0.02 14.0 0.1 0.04 13.0 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 KXG53392.1 - 0.025 14.2 0.0 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KXG53392.1 - 0.026 13.8 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Glu_dehyd_C PF16912.5 KXG53392.1 - 0.029 13.8 0.0 0.074 12.5 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Trp_halogenase PF04820.14 KXG53392.1 - 0.063 12.1 0.0 0.77 8.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.18 KXG53392.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 KXG53392.1 - 0.15 11.3 0.0 0.33 10.1 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Fungal_trans PF04082.18 KXG53393.1 - 8.8e-13 47.9 0.0 1.3e-12 47.4 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ring_hydroxyl_A PF00848.19 KXG53394.1 - 1.2e-15 58.1 11.1 9.5e-12 45.3 0.3 2.5 2 1 1 3 3 3 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KXG53394.1 - 1.3e-15 57.1 0.0 2.6e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fungal_trans PF04082.18 KXG53395.1 - 7.6e-05 21.9 0.1 0.00016 20.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2OG-FeII_Oxy PF03171.20 KXG53396.1 - 2.1e-15 57.0 0.0 2.7e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 KXG53397.1 - 2.3e-42 145.3 0.0 2.5e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 KXG53398.1 - 6.7e-35 120.7 49.7 9.2e-35 120.3 49.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG53398.1 - 4e-12 45.5 41.2 5.6e-12 45.0 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease Arylsulfotran_2 PF14269.6 KXG53399.1 - 3.5e-52 177.6 1.3 4.7e-52 177.2 1.3 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXG53399.1 - 3.4e-15 55.8 0.8 7.8e-15 54.7 0.8 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.21 KXG53399.1 - 0.024 14.6 0.1 16 5.7 0.1 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat Cyd_oper_YbgE PF09600.10 KXG53399.1 - 0.032 14.6 0.3 0.081 13.3 0.3 1.6 1 0 0 1 1 1 0 Cyd operon protein YbgE (Cyd_oper_YbgE) DUF5056 PF16479.5 KXG53399.1 - 0.14 12.4 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) RAMP4 PF06624.12 KXG53399.1 - 0.31 11.1 0.8 0.67 10.1 0.8 1.5 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 Sugar_tr PF00083.24 KXG53400.1 - 3.5e-106 355.8 25.1 4.1e-106 355.5 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG53400.1 - 8.2e-23 80.9 32.6 5.9e-16 58.3 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_11 PF00457.17 KXG53401.1 - 5.5e-75 250.9 13.2 6.3e-75 250.7 13.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Toxin_26 PF08097.11 KXG53402.1 - 0.36 11.6 3.7 1.6 9.6 0.9 2.5 2 0 0 2 2 2 0 Conotoxin T-superfamily PHY PF00360.20 KXG53403.1 - 3.2e-31 108.0 0.0 6.8e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 KXG53403.1 - 1.3e-17 64.3 0.2 3e-17 63.2 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXG53403.1 - 1.5e-15 57.3 0.0 1.5e-14 54.1 0.0 2.4 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 KXG53403.1 - 1.7e-11 44.9 0.1 7.1e-11 42.9 0.0 2.2 2 0 0 2 2 2 1 GAF domain HisKA PF00512.25 KXG53403.1 - 1e-10 41.4 0.5 3.2e-10 39.9 0.5 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 KXG53403.1 - 1.4e-09 38.6 0.0 1.1e-08 35.7 0.0 2.6 3 0 0 3 3 3 1 PAS fold HATPase_c_3 PF13589.6 KXG53403.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro_10 PF00331.20 KXG53404.1 - 3.1e-72 243.4 0.0 3.7e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 KXG53404.1 - 0.013 14.8 0.1 0.022 14.1 0.1 1.2 1 0 0 1 1 1 0 Beta-galactosidase AcetylCoA_hyd_C PF13336.6 KXG53404.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Glyco_transf_28 PF03033.20 KXG53405.1 - 8.7e-25 87.4 0.0 1.8e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXG53405.1 - 0.0034 16.2 0.0 0.0051 15.7 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 KXG53405.1 - 0.044 13.6 0.3 0.1 12.4 0.3 1.5 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Glyco_tran_28_C PF04101.16 KXG53405.1 - 0.099 12.6 0.0 0.26 11.3 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.11 KXG53405.1 - 0.13 12.6 0.2 1 9.8 0.0 2.6 3 0 0 3 3 3 0 Autophagy-related protein C terminal domain MFS_1 PF07690.16 KXG53406.1 - 4.1e-43 147.6 44.2 1.4e-42 145.9 43.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG53406.1 - 9.3e-16 57.7 10.4 9.3e-16 57.7 10.4 3.5 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KXG53406.1 - 1.4e-14 53.5 21.5 2.4e-14 52.7 21.5 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SirB PF04247.12 KXG53406.1 - 0.018 15.1 13.4 0.27 11.3 2.0 3.3 2 1 1 3 3 3 0 Invasion gene expression up-regulator, SirB DUF1700 PF08006.11 KXG53406.1 - 1.9 8.0 6.0 0.91 9.0 1.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1700) AgrB PF04647.15 KXG53406.1 - 9.4 5.5 14.8 0.069 12.5 2.9 2.9 2 1 1 3 3 3 0 Accessory gene regulator B E1_dh PF00676.20 KXG53408.1 - 4.3e-42 144.1 0.0 5.4e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 KXG53409.1 - 1.3e-49 168.3 0.1 4.8e-36 124.1 0.0 2.3 1 1 1 2 2 2 2 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KXG53409.1 - 5.5e-49 165.8 0.0 9e-49 165.1 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal baeRF_family12 PF18856.1 KXG53409.1 - 0.00071 20.2 0.0 0.0016 19.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 12 Dicty_CAR PF05462.11 KXG53410.1 - 8.4e-11 41.5 10.5 8.4e-11 41.5 10.5 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 KXG53410.1 - 4e-09 36.1 10.4 4e-09 36.1 10.4 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 KXG53410.1 - 1.8e-07 30.8 2.8 2.3e-07 30.4 2.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KXG53410.1 - 2.2e-06 27.6 12.7 2.2e-06 27.6 12.7 1.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 TMEMspv1-c74-12 PF11044.8 KXG53410.1 - 0.15 12.1 0.2 0.33 11.0 0.2 1.5 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Frizzled PF01534.17 KXG53410.1 - 8.6 5.3 18.7 7.7 5.5 15.5 2.3 2 1 0 2 2 2 0 Frizzled/Smoothened family membrane region Sugar_tr PF00083.24 KXG53412.1 - 1.4e-94 317.6 22.3 1.7e-94 317.3 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG53412.1 - 3.7e-28 98.5 33.4 3e-26 92.2 16.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Hydantoinase_B PF02538.14 KXG53413.1 - 5.6e-126 421.0 0.0 8.3e-126 420.4 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXG53413.1 - 4.2e-94 315.1 3.1 7.2e-93 311.0 0.9 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXG53413.1 - 1.9e-48 164.5 0.2 3.4e-46 157.2 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 KXG53413.1 - 0.00018 20.3 2.7 0.12 10.9 0.2 2.8 3 0 0 3 3 3 2 MutL protein FtsA PF14450.6 KXG53413.1 - 0.00055 20.3 0.4 1.9 8.9 0.0 2.7 2 0 0 2 2 2 2 Cell division protein FtsA Ppx-GppA PF02541.16 KXG53413.1 - 0.15 11.5 0.2 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Phage_lysozyme PF00959.19 KXG53414.1 - 1.4e-15 57.7 0.0 1.9e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme Glyco_transf_54 PF04666.13 KXG53417.1 - 5.4e-09 35.3 0.0 5.7e-08 32.0 0.0 1.9 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region AftA_C PF12249.8 KXG53417.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Arabinofuranosyltransferase A C terminal IL11 PF07400.11 KXG53418.1 - 0.059 13.0 0.6 0.16 11.6 0.1 1.7 1 1 1 2 2 2 0 Interleukin 11 FUSC PF04632.12 KXG53418.1 - 0.09 11.3 2.3 0.1 11.1 2.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family ThrE PF06738.12 KXG53419.1 - 6e-76 255.0 20.1 7.6e-69 231.7 5.2 2.6 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KXG53419.1 - 6.6e-12 45.7 8.1 6.6e-12 45.7 8.1 2.9 3 0 0 3 3 3 1 Threonine/Serine exporter, ThrE Med3 PF11593.8 KXG53419.1 - 0.19 10.9 1.6 0.3 10.2 1.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FSH1 PF03959.13 KXG53420.1 - 4.9e-28 98.2 0.0 5.7e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXG53420.1 - 0.015 15.9 0.0 0.02 15.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family ketoacyl-synt PF00109.26 KXG53421.1 - 5.7e-73 245.6 0.0 1.2e-72 244.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXG53421.1 - 2.3e-59 200.3 0.2 8.9e-58 195.1 0.0 2.5 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KXG53421.1 - 6.1e-58 196.4 0.0 1e-57 195.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXG53421.1 - 6.5e-45 154.0 0.1 2e-44 152.4 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXG53421.1 - 1.3e-37 128.4 0.0 3.5e-37 127.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXG53421.1 - 5.6e-14 52.5 0.1 1.1e-12 48.3 0.0 2.6 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KXG53421.1 - 8.4e-11 41.7 0.0 4.2e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_12 PF08242.12 KXG53421.1 - 8.6e-10 39.3 0.0 2.3e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KXG53421.1 - 4.6e-09 36.2 0.0 9.6e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.6 KXG53421.1 - 1.8e-07 31.1 0.0 4.3e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG53421.1 - 2.1e-06 28.3 0.0 1.1e-05 26.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG53421.1 - 3.6e-06 27.5 0.0 1e-05 26.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KXG53421.1 - 7.5e-05 23.0 0.0 0.0002 21.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KXG53421.1 - 0.00014 21.4 0.4 0.00031 20.2 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 KXG53421.1 - 0.00018 21.4 0.0 0.00049 19.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 KXG53421.1 - 0.00029 20.6 0.7 0.0012 18.7 0.7 1.9 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ADH_N PF08240.12 KXG53421.1 - 0.00077 19.3 2.0 0.0013 18.6 0.4 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Sacchrp_dh_NADP PF03435.18 KXG53421.1 - 0.016 15.5 0.0 0.07 13.4 0.0 2.1 2 0 0 2 2 1 0 Saccharopine dehydrogenase NADP binding domain ACP_syn_III PF08545.10 KXG53421.1 - 0.024 14.5 0.1 0.097 12.5 0.1 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N_2 PF13602.6 KXG53421.1 - 0.029 15.4 0.0 0.19 12.8 0.0 2.4 2 0 0 2 2 1 0 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.15 KXG53421.1 - 0.048 12.8 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Ubie_methyltran PF01209.18 KXG53421.1 - 0.14 11.5 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Pkinase PF00069.25 KXG53422.1 - 6.7e-16 58.4 0.0 3.4e-15 56.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG53422.1 - 1.8e-07 30.8 0.0 3.5e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXG53422.1 - 0.053 12.9 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXG53422.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pyr_redox_2 PF07992.14 KXG53423.1 - 1.3e-17 64.0 0.0 3.7e-17 62.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXG53423.1 - 2e-05 23.9 0.4 0.00043 19.5 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KXG53423.1 - 0.0017 17.1 0.1 0.0051 15.6 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KXG53423.1 - 0.0021 17.4 0.3 0.0039 16.5 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXG53423.1 - 0.0024 17.5 1.0 0.0039 16.8 0.9 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG53423.1 - 0.0041 17.3 0.2 0.013 15.7 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXG53423.1 - 0.0053 16.0 1.5 0.058 12.6 0.2 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXG53423.1 - 0.0072 15.4 0.2 0.012 14.7 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXG53423.1 - 0.024 13.9 0.1 0.038 13.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KXG53423.1 - 0.12 12.4 1.3 0.35 10.8 0.8 2.0 1 1 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXG53423.1 - 0.15 10.9 0.1 0.22 10.3 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ABC2_membrane PF01061.24 KXG53424.1 - 1.6e-81 272.8 52.6 3.3e-46 157.3 16.8 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KXG53424.1 - 5.4e-40 137.1 0.0 8.8e-19 68.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXG53424.1 - 5.4e-27 93.5 0.3 5.4e-27 93.5 0.3 3.9 4 0 0 4 4 4 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 KXG53424.1 - 4.5e-09 35.9 40.4 5e-05 22.6 21.3 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 KXG53424.1 - 6.5e-05 22.6 0.1 0.001 18.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXG53424.1 - 8.4e-05 23.0 0.6 0.098 13.0 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXG53424.1 - 0.00013 22.2 0.1 1 9.6 0.0 3.3 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 KXG53424.1 - 0.00032 20.9 0.0 0.24 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_trans_N PF14510.6 KXG53424.1 - 0.00044 20.8 0.0 0.0013 19.2 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_29 PF13555.6 KXG53424.1 - 0.00053 19.7 1.0 0.085 12.6 0.1 3.2 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KXG53424.1 - 0.002 18.4 1.0 0.91 9.7 0.5 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXG53424.1 - 0.0027 17.6 0.6 0.012 15.6 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KXG53424.1 - 0.0042 17.6 0.0 2.5 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXG53424.1 - 0.0098 15.8 0.7 1.9 8.4 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.6 KXG53424.1 - 0.012 15.5 0.0 3.3 7.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 KXG53424.1 - 0.017 14.7 2.3 2 8.0 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KXG53424.1 - 0.029 14.1 0.6 8.2 6.2 0.2 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 KXG53424.1 - 0.053 14.0 0.0 15 6.0 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KXG53424.1 - 0.073 12.8 0.5 5.8 6.6 0.3 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KXG53424.1 - 0.2 11.6 0.1 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KXG53424.1 - 0.31 10.3 1.1 5.6 6.2 0.3 2.4 2 0 0 2 2 2 0 Zeta toxin MFS_1 PF07690.16 KXG53425.1 - 1.4e-35 122.9 21.0 3e-35 121.8 21.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily WCOR413 PF05562.11 KXG53425.1 - 0.041 13.8 1.6 2.2 8.2 0.1 3.0 2 1 0 3 3 3 0 Cold acclimation protein WCOR413 IATP PF04568.12 KXG53426.1 - 1.2e-19 70.5 1.7 1.4e-19 70.3 1.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Trimer_CC PF08954.11 KXG53426.1 - 0.0093 15.5 2.8 0.02 14.5 2.8 1.6 1 1 0 1 1 1 1 Trimerisation motif Takusan PF04822.13 KXG53426.1 - 0.015 15.1 1.0 0.015 15.1 1.0 1.5 2 0 0 2 2 2 0 Takusan DUF3347 PF11827.8 KXG53426.1 - 0.023 14.9 0.6 0.026 14.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) TssO PF17561.2 KXG53426.1 - 0.029 14.5 0.6 0.036 14.2 0.6 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO MFS_1 PF07690.16 KXG53427.1 - 1.9e-31 109.3 57.5 3.9e-29 101.7 47.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXG53427.1 - 0.0014 17.2 38.8 0.039 12.5 17.5 3.2 1 1 2 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.24 KXG53427.1 - 0.0086 15.0 39.6 0.015 14.2 15.6 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter Phage_holin_2_3 PF16080.5 KXG53427.1 - 0.58 10.0 7.8 0.27 11.0 0.2 3.5 3 0 0 3 3 3 0 Bacteriophage holin family HP1 Lipase_2 PF01674.18 KXG53429.1 - 5.6e-07 29.3 0.0 9.8e-07 28.5 0.0 1.4 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 KXG53429.1 - 1.5e-06 28.1 0.1 8e-06 25.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG53429.1 - 4.5e-05 24.2 0.1 5.4e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KXG53429.1 - 0.012 15.5 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 KXG53429.1 - 0.024 13.9 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF900 PF05990.12 KXG53429.1 - 0.066 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) HCV_env PF01539.17 KXG53429.1 - 0.14 11.8 0.0 1.1 8.9 0.0 2.2 1 1 1 2 2 2 0 Hepatitis C virus envelope glycoprotein E1 DHC_N2 PF08393.13 KXG53430.1 - 0.016 14.3 1.4 0.028 13.6 0.5 1.7 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 Myb_DNA-bind_6 PF13921.6 KXG53430.1 - 0.025 14.8 0.1 0.43 10.9 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain I_LWEQ PF01608.17 KXG53430.1 - 0.067 13.4 3.4 0.072 13.3 1.6 1.9 2 0 0 2 2 2 0 I/LWEQ domain FlxA PF14282.6 KXG53430.1 - 0.078 13.0 2.2 0.18 11.8 2.2 1.5 1 0 0 1 1 1 0 FlxA-like protein APG6_N PF17675.1 KXG53430.1 - 0.21 12.1 8.6 4.1 7.9 5.7 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Laminin_II PF06009.12 KXG53430.1 - 1.9 8.5 6.4 5.5 7.0 1.9 2.6 2 1 0 2 2 2 0 Laminin Domain II Abhydrolase_4 PF08386.10 KXG53432.1 - 4.3e-26 91.0 0.0 9.4e-26 89.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KXG53432.1 - 4.5e-17 62.6 0.0 7.6e-14 52.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG53432.1 - 0.07 12.4 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Aldolase_II PF00596.21 KXG53433.1 - 7.6e-49 166.2 0.1 1.1e-48 165.7 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TIG_plexin PF17960.1 KXG53436.1 - 0.0071 16.3 0.1 2.4 8.2 0.0 2.5 2 0 0 2 2 2 2 TIG domain Cu_amine_oxid PF01179.20 KXG53437.1 - 1.7e-162 541.1 0.3 2e-162 540.8 0.3 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KXG53437.1 - 2.3e-06 27.9 0.0 5.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KXG53437.1 - 1.2e-05 25.5 0.1 2.3e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF5026 PF16429.5 KXG53437.1 - 0.024 14.7 0.0 0.072 13.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5026) MFS_1 PF07690.16 KXG53438.1 - 1.8e-43 148.8 62.7 3.6e-43 147.9 59.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG53438.1 - 6.3e-17 61.2 29.2 3e-16 59.0 29.0 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXG53438.1 - 3.5e-13 49.2 11.8 3.5e-13 49.2 11.8 4.0 4 0 0 4 4 4 1 Sugar (and other) transporter DUF1146 PF06612.11 KXG53438.1 - 2 8.5 5.8 1.4 9.1 1.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) Isochorismatase PF00857.20 KXG53439.1 - 3.5e-34 118.5 0.0 4e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Mic1 PF07035.12 KXG53439.1 - 0.028 14.1 0.1 0.044 13.5 0.1 1.4 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like DDE_1 PF03184.19 KXG53440.1 - 2.3e-10 40.4 0.0 3.9e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KXG53440.1 - 0.1 12.6 0.1 0.36 10.9 0.1 1.9 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 KXG53441.1 - 1.2e-14 54.3 0.0 2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Acetyltransf_7 PF13508.7 KXG53442.1 - 1e-05 25.9 0.1 1.7e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXG53442.1 - 6.4e-05 22.9 0.1 9.3e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXG53442.1 - 0.0001 22.4 0.1 0.00016 21.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG53442.1 - 0.00013 22.2 0.0 0.0002 21.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KXG53442.1 - 0.0017 18.3 0.1 0.0029 17.5 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 KXG53442.1 - 0.0022 17.6 0.0 0.003 17.2 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_15 PF17013.5 KXG53442.1 - 0.25 10.8 0.0 0.82 9.1 0.0 1.7 2 0 0 2 2 2 0 Putative acetyl-transferase NAAA-beta PF15508.6 KXG53443.1 - 0.079 13.3 4.2 73 3.8 0.0 7.0 9 1 0 10 10 10 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase ApoB100_C PF12491.8 KXG53443.1 - 0.12 12.3 1.2 21 5.1 0.1 4.8 5 1 0 5 5 5 0 Apolipoprotein B100 C terminal Secretin_N_2 PF07655.13 KXG53443.1 - 0.14 12.7 2.9 0.5 11.0 2.9 2.0 1 0 0 1 1 1 0 Secretin N-terminal domain AI-2E_transport PF01594.16 KXG53443.1 - 0.18 10.9 13.4 1.1 8.3 0.4 5.1 2 1 2 6 6 6 0 AI-2E family transporter SPX PF03105.19 KXG53443.1 - 0.53 10.1 6.0 0.78 9.6 6.0 1.2 1 0 0 1 1 1 0 SPX domain Ribosomal_L27_C PF18471.1 KXG53443.1 - 0.71 9.2 3.1 1.9e+02 1.3 0.0 5.0 6 2 1 7 7 7 0 Ribosomal L27 protein C-terminal domain Casc1_N PF15927.5 KXG53443.1 - 1.5 8.5 7.3 4.2 7.0 0.0 3.1 4 0 0 4 4 4 0 Cancer susceptibility candidate 1 N-terminus SOG2 PF10428.9 KXG53443.1 - 3.3 6.8 14.3 6.1 5.9 14.3 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein APH PF01636.23 KXG53444.1 - 3e-13 50.3 0.0 4e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXG53444.1 - 0.0017 17.9 0.0 0.0045 16.6 0.0 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase RNA_pol_I_TF PF04090.12 KXG53444.1 - 0.015 14.8 0.0 0.077 12.5 0.0 1.8 1 1 1 2 2 2 0 RNA polymerase I specific initiation factor Fungal_trans PF04082.18 KXG53445.1 - 2.9e-10 39.6 0.3 6.5e-10 38.5 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG53445.1 - 1.9e-08 34.3 10.9 1.9e-08 34.3 10.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mak10 PF04112.13 KXG53446.1 - 6.2e-61 204.8 0.0 1.1e-60 203.9 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.13 KXG53447.1 - 1.8e-23 82.2 1.4 1.8e-23 82.2 1.4 1.4 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain DASH_Spc34 PF08657.10 KXG53448.1 - 0.42 10.4 6.0 0.093 12.5 1.5 2.0 2 0 0 2 2 2 0 DASH complex subunit Spc34 Phage_Gp23 PF10669.9 KXG53448.1 - 4.5 7.6 8.0 7.2 7.0 2.6 2.5 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) TerB_C PF15615.6 KXG53448.1 - 6.2 7.1 9.9 1.5 9.1 4.6 2.2 2 0 0 2 2 2 0 TerB-C domain Cpn60_TCP1 PF00118.24 KXG53449.1 - 3.1e-85 286.7 7.3 4.6e-85 286.1 7.3 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HATPase_c PF02518.26 KXG53450.1 - 6.6e-31 107.1 0.1 1.9e-30 105.6 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 KXG53450.1 - 2.9e-29 101.2 17.4 2.2e-08 34.3 0.3 6.8 5 3 2 7 7 7 4 HAMP domain Response_reg PF00072.24 KXG53450.1 - 1.3e-28 99.4 0.2 2.2e-27 95.4 0.3 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KXG53450.1 - 3.7e-15 55.7 1.6 1.4e-14 53.9 0.4 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain DUF1843 PF08898.10 KXG53450.1 - 0.002 18.6 1.7 24 5.5 0.0 5.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Syntaxin_2 PF14523.6 KXG53450.1 - 0.0027 18.0 10.6 0.98 9.8 0.0 5.4 4 1 1 5 5 5 2 Syntaxin-like protein DUF3829 PF12889.7 KXG53450.1 - 0.0074 15.8 1.7 1.3 8.4 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3829) DUF948 PF06103.11 KXG53450.1 - 0.021 15.1 31.3 0.85 9.9 1.4 7.3 5 2 3 8 8 8 0 Bacterial protein of unknown function (DUF948) AdHead_fibreRBD PF16812.5 KXG53450.1 - 0.073 12.9 2.9 0.2 11.5 0.0 2.7 3 0 0 3 3 3 0 C-terminal head domain of the fowl adenovirus type 1 long fibre Cnn_1N PF07989.11 KXG53450.1 - 1.2 9.4 3.8 6.6 7.0 0.0 3.3 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF4795 PF16043.5 KXG53450.1 - 2.5 7.6 10.6 63 3.1 4.3 3.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) TMF_TATA_bd PF12325.8 KXG53450.1 - 6.3 7.0 12.2 11 6.3 1.0 4.9 5 1 1 6 6 6 0 TATA element modulatory factor 1 TATA binding Mito_carr PF00153.27 KXG53451.1 - 1.8e-58 194.4 0.3 9.6e-18 63.9 0.0 4.4 4 0 0 4 4 4 4 Mitochondrial carrier protein CorA PF01544.18 KXG53451.1 - 3.8e-09 36.3 0.3 3.8e-09 36.3 0.3 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF676 PF05057.14 KXG53451.1 - 2.9e-06 27.0 0.0 1e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KXG53451.1 - 0.0001 22.1 0.0 0.00032 20.5 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 KXG53451.1 - 0.0017 17.7 0.1 0.0065 15.8 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXG53451.1 - 0.013 16.1 0.0 0.013 16.1 0.0 2.7 3 0 0 3 3 3 0 Alpha/beta hydrolase family Herpes_U59 PF04529.12 KXG53451.1 - 0.033 13.3 0.5 0.065 12.3 0.1 1.6 2 0 0 2 2 2 0 Herpesvirus U59 protein DUF4226 PF10774.9 KXG53451.1 - 3.4 8.0 6.6 3.2 8.1 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4226) Ank_2 PF12796.7 KXG53452.1 - 2.6e-47 159.3 0.7 1e-10 42.0 0.1 7.2 6 1 1 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG53452.1 - 4.3e-40 131.1 7.0 0.00026 21.2 0.0 12.8 13 0 0 13 13 13 10 Ankyrin repeat Ank PF00023.30 KXG53452.1 - 7e-38 127.4 6.9 0.0001 22.6 0.1 11.2 11 1 1 12 12 12 8 Ankyrin repeat Ank_4 PF13637.6 KXG53452.1 - 2.6e-37 126.7 3.1 7.6e-08 32.7 0.0 9.3 7 4 4 11 11 11 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG53452.1 - 1.7e-27 95.1 3.7 4.3e-06 26.9 0.0 9.5 9 2 1 10 10 10 5 Ankyrin repeats (many copies) Phage_Gp17 PF17549.2 KXG53452.1 - 0.11 12.6 0.3 0.22 11.6 0.3 1.5 1 0 0 1 1 1 0 Gene Product 17 V-SNARE PF05008.15 KXG53453.1 - 0.0033 17.8 1.0 0.0064 16.8 1.0 1.4 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus KIP1 PF07765.12 KXG53453.1 - 0.14 12.3 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 KIP1-like protein HNH_2 PF13391.6 KXG53454.1 - 0.047 13.8 0.2 0.19 11.9 0.2 2.0 1 1 0 1 1 1 0 HNH endonuclease TFB6 PF17110.5 KXG53454.1 - 0.078 12.7 0.2 0.16 11.7 0.0 1.5 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH F-box-like PF12937.7 KXG53456.1 - 7.3e-07 29.0 0.0 1.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXG53456.1 - 0.006 16.4 0.1 0.018 14.9 0.0 1.8 2 0 0 2 2 2 1 F-box domain TPR_2 PF07719.17 KXG53456.1 - 0.16 12.2 0.4 1 9.7 0.5 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 KXG53456.1 - 0.21 11.7 0.3 0.36 10.9 0.3 1.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Fungal_trans PF04082.18 KXG53457.1 - 2.4e-07 30.1 0.4 2.4e-06 26.8 0.4 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG53457.1 - 4.5e-06 26.7 15.1 1e-05 25.5 15.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.27 KXG53458.1 - 7.4e-39 133.4 0.0 4.9e-19 69.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXG53458.1 - 3e-26 92.7 26.9 2.1e-16 60.4 18.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region T2SSE PF00437.20 KXG53458.1 - 1.4e-07 30.9 0.2 0.0033 16.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 KXG53458.1 - 6.7e-06 26.6 0.5 0.076 13.4 0.3 2.8 2 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KXG53458.1 - 7.2e-06 25.6 2.6 0.12 11.8 0.1 4.0 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXG53458.1 - 1e-05 25.9 0.0 0.25 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXG53458.1 - 3.6e-05 23.4 0.2 0.45 10.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 KXG53458.1 - 4.8e-05 23.2 0.6 0.15 11.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KXG53458.1 - 7.4e-05 22.9 0.1 0.022 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXG53458.1 - 7.5e-05 22.7 0.3 0.12 12.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KXG53458.1 - 0.00015 21.3 0.0 0.4 10.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 KXG53458.1 - 0.00021 21.9 0.1 1.2 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 KXG53458.1 - 0.00026 20.4 0.2 0.23 10.8 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.6 KXG53458.1 - 0.0003 20.4 0.3 0.28 10.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KXG53458.1 - 0.00034 21.2 0.1 0.65 10.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KXG53458.1 - 0.00069 19.6 0.3 0.12 12.3 0.1 2.8 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 KXG53458.1 - 0.00088 19.4 4.2 0.7 9.9 0.1 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_21 PF13304.6 KXG53458.1 - 0.0012 18.7 2.1 1.4 8.6 0.1 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 KXG53458.1 - 0.0013 18.0 0.0 0.15 11.4 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Dynamin_N PF00350.23 KXG53458.1 - 0.0016 18.5 1.9 0.73 9.9 0.1 2.6 3 0 0 3 3 2 1 Dynamin family cobW PF02492.19 KXG53458.1 - 0.0017 18.0 0.7 2.2 7.9 0.4 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 KXG53458.1 - 0.0021 17.1 0.4 1.1 8.1 0.2 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 KXG53458.1 - 0.0028 18.1 0.2 0.57 10.6 0.0 3.4 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KXG53458.1 - 0.0033 17.5 0.9 1.4 9.0 0.1 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 KXG53458.1 - 0.0046 17.2 0.4 5.1 7.3 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 KXG53458.1 - 0.0049 17.2 0.1 2.9 8.3 0.0 3.1 3 0 0 3 3 3 1 RNA helicase Viral_helicase1 PF01443.18 KXG53458.1 - 0.0054 16.5 0.3 0.97 9.1 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 KXG53458.1 - 0.01 15.9 0.1 5 7.1 0.2 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KXG53458.1 - 0.013 14.7 0.2 0.16 11.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.21 KXG53458.1 - 0.016 14.6 0.1 5.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KXG53458.1 - 0.035 14.1 0.0 0.72 9.9 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 KXG53458.1 - 0.042 14.1 0.2 0.49 10.7 0.0 2.7 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit ATPase_2 PF01637.18 KXG53458.1 - 0.045 13.7 0.0 10 6.0 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KXG53458.1 - 0.081 12.6 2.8 15 5.3 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 KXG53458.1 - 0.083 12.6 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DEAD PF00270.29 KXG53458.1 - 0.088 12.6 0.1 10 5.8 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase AIG1 PF04548.16 KXG53458.1 - 0.098 12.0 0.5 2.1 7.6 0.0 3.0 3 0 0 3 3 3 0 AIG1 family PduV-EutP PF10662.9 KXG53458.1 - 0.12 12.1 0.6 0.93 9.2 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 KXG53458.1 - 0.14 11.4 0.3 2.2 7.5 0.1 2.2 2 0 0 2 2 2 0 Septin AAA_15 PF13175.6 KXG53458.1 - 0.15 11.8 1.2 7.4 6.2 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain Pox_A32 PF04665.12 KXG53458.1 - 0.17 11.3 0.2 10 5.5 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 KXG53458.1 - 0.18 11.6 0.8 21 4.8 0.4 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 KXG53458.1 - 0.19 10.9 0.4 16 4.5 0.0 2.6 3 0 0 3 3 3 0 G-protein alpha subunit AAA_28 PF13521.6 KXG53458.1 - 0.65 10.2 2.3 6.2 7.0 0.3 2.6 2 0 0 2 2 2 0 AAA domain DUF4470 PF14737.6 KXG53459.1 - 9.3e-20 70.6 0.0 2.3e-19 69.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) HA2 PF04408.23 KXG53460.1 - 2.6e-21 75.9 0.1 2.6e-21 75.9 0.1 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXG53460.1 - 1.3e-13 51.1 0.0 2.9e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXG53460.1 - 2.7e-12 47.0 0.0 8.8e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXG53460.1 - 3.3e-05 23.7 0.0 6.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXG53460.1 - 0.0013 19.0 0.0 0.0052 17.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KXG53460.1 - 0.013 15.3 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KXG53460.1 - 0.019 14.7 0.0 0.067 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXG53460.1 - 0.021 14.4 0.0 0.068 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXG53460.1 - 0.024 14.1 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 KXG53460.1 - 0.029 14.7 0.0 0.12 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KXG53460.1 - 0.03 13.4 0.0 0.073 12.1 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase PF06745.13 KXG53460.1 - 0.15 11.3 0.0 0.52 9.6 0.0 1.8 2 0 0 2 2 2 0 KaiC TraF PF13728.6 KXG53461.1 - 0.03 14.1 0.1 0.071 12.9 0.1 1.6 1 0 0 1 1 1 0 F plasmid transfer operon protein Sulfatase PF00884.23 KXG53462.1 - 4.7e-45 154.3 0.2 7.2e-43 147.1 0.0 2.3 2 1 0 2 2 2 1 Sulfatase DUF4976 PF16347.5 KXG53462.1 - 2.2e-07 31.1 1.1 7.8e-07 29.3 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KXG53462.1 - 4.8e-07 29.7 0.0 3.6e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 KXG53462.1 - 0.0015 19.2 0.0 0.0033 18.1 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 KXG53462.1 - 0.0075 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF229 PF02995.17 KXG53462.1 - 0.018 13.7 0.0 0.03 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF229) STI1 PF17830.1 KXG53462.1 - 0.026 14.5 0.1 0.05 13.5 0.1 1.4 1 0 0 1 1 1 0 STI1 domain Sugar_tr PF00083.24 KXG53463.1 - 1.4e-93 314.2 20.7 1.9e-93 313.8 20.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG53463.1 - 3.3e-26 92.0 19.1 3.3e-26 92.0 19.1 2.3 1 1 0 2 2 2 1 Major Facilitator Superfamily GMC_oxred_N PF00732.19 KXG53464.1 - 8.6e-53 179.6 0.0 1.1e-52 179.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG53464.1 - 8.8e-34 117.1 0.0 1.6e-33 116.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KXG53464.1 - 0.00023 20.5 0.0 0.03 13.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG53464.1 - 0.0015 18.2 4.7 0.027 14.1 4.8 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXG53464.1 - 0.0047 16.2 0.1 0.0076 15.5 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KXG53464.1 - 0.013 14.7 0.0 2.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG53464.1 - 0.015 15.5 0.3 0.044 14.0 0.3 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXG53464.1 - 0.016 14.3 0.2 0.027 13.5 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXG53464.1 - 0.031 13.4 5.2 1.5 7.8 2.7 2.2 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KXG53464.1 - 0.081 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Glyco_hydro_5_C PF18564.1 KXG53465.1 - 7.5e-22 77.7 0.0 2.1e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KXG53465.1 - 6.7e-08 32.3 3.0 5e-07 29.4 1.4 2.5 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) UFC1 PF08694.11 KXG53465.1 - 0.006 16.2 0.1 0.034 13.8 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-fold modifier-conjugating enzyme 1 FMO-like PF00743.19 KXG53466.1 - 4.4e-12 45.2 0.0 2.4e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXG53466.1 - 1.7e-08 34.5 0.3 2.2e-06 27.8 0.0 3.5 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXG53466.1 - 5.7e-07 29.1 0.0 8.1e-06 25.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG53466.1 - 2e-06 27.2 0.1 0.0002 20.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXG53466.1 - 3.4e-06 26.5 0.0 0.00075 18.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG53466.1 - 0.00052 19.7 0.0 0.05 13.2 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXG53466.1 - 0.00081 19.4 0.9 0.026 14.5 0.0 3.3 3 2 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXG53466.1 - 0.0012 18.2 0.0 0.15 11.3 0.0 2.7 3 0 0 3 3 3 1 Thi4 family 2-Hacid_dh_C PF02826.19 KXG53466.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXG53466.1 - 0.011 15.8 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 KXG53466.1 - 0.084 13.3 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Dyp_perox PF04261.12 KXG53467.1 - 3.6e-86 289.1 0.0 4.1e-86 288.9 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family adh_short_C2 PF13561.6 KXG53468.1 - 5.5e-61 206.1 1.7 7.6e-61 205.6 1.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXG53468.1 - 1.9e-49 167.8 0.8 3.3e-49 167.0 0.8 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXG53468.1 - 5.2e-14 52.5 2.4 8.1e-13 48.7 2.4 2.1 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXG53468.1 - 1.6e-07 30.8 0.4 3.1e-07 29.8 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXG53468.1 - 0.00015 21.3 0.5 0.00049 19.6 0.5 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG53468.1 - 0.015 14.7 0.1 0.028 13.8 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Adeno_PIX PF03955.14 KXG53468.1 - 0.077 13.2 1.5 0.11 12.6 0.1 1.9 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Ldh_1_N PF00056.23 KXG53468.1 - 0.085 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 KXG53469.1 - 1.9e-56 191.6 3.4 2.5e-56 191.2 3.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain CRISPR_Cas2 PF09827.9 KXG53469.1 - 0.063 13.5 0.7 2.7 8.2 0.3 2.5 1 1 1 2 2 2 0 CRISPR associated protein Cas2 adh_short PF00106.25 KXG53470.1 - 1.5e-38 132.2 2.8 1.7e-38 132.1 2.8 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG53470.1 - 3.3e-37 128.3 2.4 4e-37 128.0 2.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG53470.1 - 2.1e-08 34.3 1.6 3.3e-08 33.7 1.6 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KXG53470.1 - 0.042 13.8 2.1 0.33 10.9 2.1 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 KXG53470.1 - 0.17 11.8 0.6 0.23 11.3 0.1 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SH3_3 PF08239.11 KXG53471.1 - 1.7e-05 25.0 0.0 3.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain NLPC_P60 PF00877.19 KXG53471.1 - 0.024 14.7 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 NlpC/P60 family Ank_2 PF12796.7 KXG53472.1 - 8.2e-20 71.2 9.0 2.7e-10 40.7 0.3 2.8 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG53472.1 - 4.5e-15 55.8 0.4 9.6e-07 29.2 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG53472.1 - 1.4e-11 43.5 1.1 4.4e-05 23.6 0.1 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KXG53472.1 - 2.3e-09 37.3 5.0 7.2e-06 26.2 0.9 4.1 3 0 0 3 3 3 2 Ankyrin repeat NACHT PF05729.12 KXG53472.1 - 5.1e-09 36.3 0.0 1.3e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXG53472.1 - 2.8e-08 34.3 0.5 2.4e-07 31.3 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain Ank_5 PF13857.6 KXG53472.1 - 5.7e-08 32.9 5.6 5.6e-05 23.4 0.3 4.0 2 2 2 4 4 4 1 Ankyrin repeats (many copies) AAA_22 PF13401.6 KXG53472.1 - 4.3e-06 27.1 1.0 0.00033 20.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KXG53472.1 - 0.011 15.0 0.1 0.27 10.5 0.0 2.4 1 1 1 2 2 2 0 KAP family P-loop domain DUF2075 PF09848.9 KXG53472.1 - 0.033 13.4 1.4 0.16 11.2 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KXG53472.1 - 0.099 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Clat_adaptor_s PF01217.20 KXG53473.1 - 5.8e-11 42.5 0.0 3.3e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Mu-like_Pro PF10123.9 KXG53474.1 - 0.31 10.6 11.9 0.046 13.3 8.1 1.5 2 0 0 2 2 2 0 Mu-like prophage I protein Fungal_trans PF04082.18 KXG53475.1 - 1e-05 24.8 0.0 1.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GP3 PF03076.14 KXG53475.1 - 0.02 14.9 0.2 0.19 11.8 0.0 2.3 2 0 0 2 2 2 0 Equine arteritis virus GP3 PQ-loop PF04193.14 KXG53476.1 - 1.9e-34 117.2 12.8 6.6e-19 67.4 1.6 3.5 4 0 0 4 4 4 2 PQ loop repeat CYSTM PF12734.7 KXG53476.1 - 0.018 15.4 0.0 0.018 15.4 0.0 2.2 4 0 0 4 4 4 0 Cysteine-rich TM module stress tolerance Ribosomal_L16 PF00252.18 KXG53477.1 - 4e-45 153.1 0.1 5.1e-45 152.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e NFACT-C PF11923.8 KXG53478.1 - 2.4e-40 136.7 0.2 2.4e-40 136.7 0.2 3.8 4 0 0 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 KXG53478.1 - 5.8e-35 120.9 12.3 5.8e-35 120.9 12.3 2.3 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KXG53478.1 - 2.6e-27 95.6 0.0 6.1e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain Sua5_yciO_yrdC PF01300.18 KXG53479.1 - 1.6e-54 184.1 0.0 2.4e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KXG53479.1 - 5.1e-33 114.5 0.0 1e-32 113.5 0.0 1.5 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding A_deaminase PF00962.22 KXG53480.1 - 1e-80 271.6 0.0 1.1e-80 271.4 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KXG53480.1 - 0.015 14.6 0.0 0.12 11.6 0.0 2.2 2 1 0 2 2 2 0 Amidohydrolase family 2Fe-2S_thioredx PF01257.19 KXG53482.1 - 1.3e-59 200.2 0.1 1.6e-59 199.9 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin HSP9_HSP12 PF04119.12 KXG53482.1 - 0.053 13.9 0.0 0.25 11.7 0.0 1.9 2 0 0 2 2 2 0 Heat shock protein 9/12 SNF2_N PF00176.23 KXG53483.1 - 1.2e-18 67.0 0.0 2.3e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 KXG53483.1 - 2.5e-14 53.4 0.0 8.1e-14 51.7 0.0 1.9 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 KXG53483.1 - 0.0048 17.2 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG53483.1 - 0.011 15.7 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 KXG53483.1 - 0.067 13.2 24.2 0.022 14.7 7.2 2.6 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXG53483.1 - 0.07 13.0 15.0 0.36 10.7 6.4 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXG53483.1 - 0.071 13.1 13.6 1.1 9.3 1.3 2.6 2 0 0 2 2 2 0 RING-type zinc-finger FYVE PF01363.21 KXG53483.1 - 1.2 9.4 13.0 7 6.9 4.9 2.6 2 0 0 2 2 2 0 FYVE zinc finger zf-RING_2 PF13639.6 KXG53483.1 - 2 8.8 24.8 0.073 13.4 7.5 2.7 2 0 0 2 2 2 0 Ring finger domain Vfa1 PF08432.10 KXG53483.1 - 2.3 8.5 7.5 4.6 7.5 6.1 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 zf-C3HC4 PF00097.25 KXG53483.1 - 7.2 6.6 23.6 0.079 12.8 7.2 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CSTF2_hinge PF14327.6 KXG53484.1 - 2.8e-31 107.8 2.5 2.8e-31 107.8 2.5 2.3 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KXG53484.1 - 2.8e-19 68.7 0.0 4.7e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KXG53484.1 - 4.6e-17 61.3 11.9 4.6e-17 61.3 11.9 3.5 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KXG53484.1 - 0.01 15.9 0.1 0.8 9.9 0.0 2.6 1 1 1 2 2 2 0 RNA recognition motif Spo7_2_N PF15407.6 KXG53484.1 - 0.01 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_5 PF13893.6 KXG53484.1 - 0.049 13.2 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXG53484.1 - 0.071 13.0 0.0 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KXG53484.1 - 0.11 12.3 0.0 4 7.2 0.0 2.2 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain Band_7 PF01145.25 KXG53485.1 - 5.6e-24 85.1 3.0 8.9e-24 84.5 3.0 1.3 1 1 0 1 1 1 1 SPFH domain / Band 7 family RSN1_7TM PF02714.15 KXG53487.1 - 3.5e-88 295.5 30.3 3.5e-88 295.5 30.3 2.1 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXG53487.1 - 1.1e-48 164.9 0.3 1.1e-48 164.9 0.3 3.6 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXG53487.1 - 6.7e-32 111.1 0.3 4.1e-18 66.2 0.1 2.5 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KXG53487.1 - 3.2e-13 49.7 0.0 8.6e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Herpes_UL25 PF01499.16 KXG53487.1 - 0.38 9.2 1.0 0.82 8.1 0.9 1.6 1 1 1 2 2 2 0 Herpesvirus UL25 family TAF4 PF05236.14 KXG53487.1 - 1 9.0 11.5 0.33 10.7 4.9 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family MCM PF00493.23 KXG53488.1 - 3.3e-102 340.3 0.0 4.7e-102 339.8 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXG53488.1 - 2.9e-39 133.8 0.7 6.6e-39 132.6 0.7 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXG53488.1 - 5.5e-29 100.4 0.6 1.1e-28 99.4 0.6 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXG53488.1 - 7.1e-15 55.5 0.1 2.5e-14 53.7 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXG53488.1 - 6e-06 25.8 0.0 0.00017 21.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXG53488.1 - 1.3e-05 25.2 0.0 3.1e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXG53488.1 - 0.002 18.0 0.0 0.006 16.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXG53488.1 - 0.15 11.8 0.1 5.9 6.6 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain VTC PF09359.10 KXG53489.1 - 7.8e-101 337.1 0.3 1.5e-100 336.2 0.3 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KXG53489.1 - 7e-13 48.8 3.7 7e-13 48.8 3.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KXG53489.1 - 1.9e-11 44.5 18.2 2e-05 24.7 0.1 4.0 3 1 1 4 4 4 3 SPX domain RexA PF15969.5 KXG53489.1 - 0.074 12.6 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Intracellular sensor of Lambda phage, Abi component DEAD PF00270.29 KXG53490.1 - 4.4e-17 62.4 0.0 1.2e-16 61.0 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXG53490.1 - 2.7e-08 34.0 0.0 4.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXG53490.1 - 1.5e-07 31.8 0.0 5.2e-07 30.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXG53490.1 - 0.017 15.4 0.0 0.15 12.4 0.0 2.5 1 1 0 1 1 1 0 AAA domain DUF4332 PF14229.6 KXG53490.1 - 0.022 15.0 0.0 0.062 13.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) zf-HC5HC2H_2 PF13832.6 KXG53491.1 - 6.9e-22 77.7 0.2 6.9e-22 77.7 0.2 4.3 4 1 1 5 5 5 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KXG53491.1 - 4e-20 71.9 0.5 4e-20 71.9 0.5 4.4 4 1 0 4 4 4 2 PHD-like zinc-binding domain BAH PF01426.18 KXG53491.1 - 8.5e-15 54.7 0.0 1.8e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 KXG53491.1 - 1.2e-10 41.1 22.1 9.5e-07 28.6 8.2 5.1 6 0 0 6 6 6 2 PHD-finger PHD_2 PF13831.6 KXG53491.1 - 5.1e-09 35.5 4.9 5.1e-09 35.5 4.9 5.1 6 0 0 6 6 6 2 PHD-finger Myb_DNA-binding PF00249.31 KXG53491.1 - 5.8e-05 23.2 1.7 0.00018 21.6 0.1 2.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain C1_2 PF03107.16 KXG53491.1 - 0.033 14.5 0.7 0.033 14.5 0.7 6.1 6 0 0 6 6 6 0 C1 domain GATA PF00320.27 KXG53491.1 - 0.84 9.3 14.4 1.2 8.8 0.7 5.0 4 0 0 4 4 4 0 GATA zinc finger ADH_zinc_N PF00107.26 KXG53492.1 - 3e-23 82.2 0.0 4.7e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG53492.1 - 1.9e-17 64.6 0.0 3.1e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG53492.1 - 4.3e-09 36.2 0.0 1.3e-07 31.5 0.0 2.2 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain PDEase_I PF00233.19 KXG53493.1 - 9.6e-71 238.3 0.0 1.4e-70 237.7 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase G-gamma PF00631.22 KXG53494.1 - 1.3e-24 86.0 0.1 1.5e-24 85.8 0.1 1.1 1 0 0 1 1 1 1 GGL domain DUF3220 PF11516.8 KXG53494.1 - 0.073 13.3 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) PCI PF01399.27 KXG53495.1 - 2.6e-09 37.5 0.0 2.6e-09 37.5 0.0 3.4 3 1 0 3 3 3 1 PCI domain Acetyltransf_1 PF00583.25 KXG53497.1 - 7.5e-09 35.8 0.0 1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXG53497.1 - 1.1e-06 28.5 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG53497.1 - 2.1e-06 27.6 0.0 3.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KXG53497.1 - 2.1e-05 24.8 0.0 2.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXG53497.1 - 0.0062 16.6 0.2 0.013 15.6 0.2 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KXG53498.1 - 1.1e-20 73.9 50.6 9.5e-15 54.4 32.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4808 PF16066.5 KXG53498.1 - 0.036 14.6 0.1 0.068 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) RNA_pol_Rpb6 PF01192.22 KXG53499.1 - 6e-17 61.3 0.1 9.6e-17 60.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.26 KXG53500.1 - 3.7e-30 102.7 58.3 1.7e-05 25.0 0.1 10.9 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXG53500.1 - 2.6e-19 68.7 57.1 0.00011 22.5 0.4 11.0 11 0 0 11 11 11 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXG53500.1 - 4.1e-19 67.6 55.9 0.019 15.8 0.1 11.0 11 0 0 11 11 11 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXG53500.1 - 4.9e-09 36.3 10.3 0.25 11.7 0.0 8.6 10 0 0 10 10 9 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KXG53500.1 - 8.5e-06 26.3 37.0 0.28 11.8 0.1 8.8 7 1 2 9 9 9 3 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KXG53500.1 - 8e-05 22.9 25.3 2.1 8.7 2.5 5.5 3 2 2 5 5 5 4 C2H2-type zinc ribbon GAGA PF09237.11 KXG53500.1 - 0.0047 16.7 6.9 0.0079 16.0 1.6 3.2 3 0 0 3 3 3 1 GAGA factor zf-C2H2_11 PF16622.5 KXG53500.1 - 0.01 15.6 21.1 0.87 9.4 0.1 6.0 7 0 0 7 7 6 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 KXG53500.1 - 0.017 15.2 21.5 0.83 9.8 0.0 5.9 3 2 3 6 6 6 0 Aberrant zinc-finger zf-met PF12874.7 KXG53500.1 - 0.032 14.6 9.2 6.6 7.3 0.0 6.8 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KXG53500.1 - 0.32 10.8 0.0 0.32 10.8 0.0 9.4 10 1 0 10 10 10 0 C2H2-type zinc-finger domain zf_Hakai PF18408.1 KXG53500.1 - 1.2 8.9 0.0 0.16 11.7 0.7 6.1 8 0 0 8 8 8 0 C2H2 Hakai zinc finger domain PH PF00169.29 KXG53501.1 - 8e-08 32.8 0.0 2.4e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 PH domain MFS_1 PF07690.16 KXG53502.1 - 1.1e-31 110.1 27.1 2.9e-30 105.4 26.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG53502.1 - 0.00054 18.5 2.1 0.00054 18.5 2.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) COPIIcoated_ERV PF07970.12 KXG53503.1 - 4.7e-83 278.4 0.0 2.5e-82 276.0 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KXG53503.1 - 2.5e-29 101.4 0.0 5.3e-29 100.4 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TAP_C PF03943.13 KXG53504.1 - 3.9e-17 61.6 1.5 8.3e-17 60.6 1.5 1.6 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.7 KXG53504.1 - 3e-05 24.3 3.1 0.01 16.3 0.1 2.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) NTF2 PF02136.20 KXG53504.1 - 3.2e-05 24.5 0.0 7.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.6 KXG53504.1 - 0.00054 19.7 0.2 0.0022 17.7 0.2 2.1 1 1 0 1 1 1 1 Leucine rich repeat RRM_9 PF18444.1 KXG53504.1 - 0.00085 19.1 0.0 0.0023 17.7 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif LRR_9 PF14580.6 KXG53504.1 - 0.0017 17.9 0.1 0.0031 17.0 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 KXG53504.1 - 0.18 11.9 2.6 13 6.1 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat Vps53_N PF04100.12 KXG53505.1 - 5.1e-109 364.7 2.5 5.1e-109 364.7 2.5 1.7 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 KXG53505.1 - 4.5e-06 26.2 7.2 1.1e-05 24.9 7.2 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KXG53505.1 - 1.3e-05 25.2 0.2 4.1e-05 23.5 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) RINT1_TIP1 PF04437.13 KXG53505.1 - 0.00014 21.0 1.6 0.00014 21.0 1.6 3.4 2 2 1 3 3 3 1 RINT-1 / TIP-1 family COG2 PF06148.11 KXG53505.1 - 0.0089 16.1 3.7 0.0089 16.1 3.7 2.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 FtsK_SpoIIIE PF01580.18 KXG53505.1 - 0.021 14.2 0.5 0.042 13.2 0.5 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sec8_exocyst PF04048.14 KXG53505.1 - 0.035 14.0 2.3 0.19 11.6 2.3 2.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Sigma70_ner PF04546.13 KXG53505.1 - 0.14 12.0 8.6 0.022 14.7 4.3 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region zf-C4H2 PF10146.9 KXG53505.1 - 0.21 11.8 2.1 0.62 10.3 2.1 1.8 1 0 0 1 1 1 0 Zinc finger-containing protein APG6_N PF17675.1 KXG53505.1 - 0.22 12.1 8.3 0.06 13.9 4.2 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region XhlA PF10779.9 KXG53505.1 - 0.34 11.2 6.6 0.17 12.1 3.4 2.2 2 0 0 2 2 2 0 Haemolysin XhlA DUF1515 PF07439.11 KXG53505.1 - 0.89 9.6 3.5 0.62 10.1 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Spc7 PF08317.11 KXG53505.1 - 0.94 8.3 11.6 0.058 12.3 6.2 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 KXG53505.1 - 1.3 9.2 6.0 1.1 9.5 3.0 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin_2 PF14523.6 KXG53505.1 - 2.8 8.4 6.5 2.4 8.6 3.0 2.9 3 0 0 3 3 2 0 Syntaxin-like protein Acetyltransf_1 PF00583.25 KXG53506.1 - 1.3e-14 54.4 0.1 1.8e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXG53506.1 - 1.1e-12 47.9 0.0 1.4e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXG53506.1 - 2.4e-12 47.1 0.0 3.8e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG53506.1 - 0.00018 21.4 0.1 0.00042 20.2 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXG53506.1 - 0.0083 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 KXG53506.1 - 0.016 15.4 0.1 0.027 14.6 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXG53506.1 - 0.027 14.5 0.0 0.06 13.4 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 KXG53506.1 - 0.16 11.7 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ BTB PF00651.31 KXG53507.1 - 0.00016 21.9 0.0 0.00025 21.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.16 KXG53508.1 - 9.2e-21 74.1 28.2 9.2e-21 74.1 28.2 2.8 1 1 1 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 KXG53508.1 - 0.0097 14.2 0.8 0.044 12.1 0.4 2.3 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Ribosomal_L10 PF00466.20 KXG53509.1 - 1.2e-23 83.2 0.1 2.7e-23 82.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 KXG53509.1 - 3.9e-22 78.0 0.0 8.4e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KXG53509.1 - 2.3e-20 73.0 2.2 2.3e-20 73.0 2.2 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein Holin_SPP1 PF04688.13 KXG53509.1 - 0.13 12.5 0.1 0.58 10.4 0.1 2.0 1 1 1 2 2 2 0 SPP1 phage holin WD40 PF00400.32 KXG53510.1 - 0.0031 18.3 0.8 0.039 14.8 0.1 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat URO-D PF01208.17 KXG53511.1 - 3.6e-128 427.6 0.0 4e-128 427.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) dCMP_cyt_deam_1 PF00383.23 KXG53512.1 - 1.3e-21 76.4 0.0 1.8e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXG53512.1 - 6e-19 68.2 0.0 7e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KXG53512.1 - 1e-05 25.6 2.2 0.1 12.7 1.1 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase SNAD4 PF18750.1 KXG53512.1 - 0.00027 21.0 0.0 0.0023 18.0 0.0 2.0 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD2 PF18782.1 KXG53512.1 - 0.0055 16.8 0.0 0.02 15.0 0.0 1.8 1 1 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 KXG53512.1 - 0.0085 16.0 0.2 0.017 15.0 0.1 1.5 1 1 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC2 PF18772.1 KXG53512.1 - 0.01 15.9 0.2 0.05 13.7 0.2 1.9 1 1 0 1 1 1 0 APOBEC2 NAD1 PF18778.1 KXG53512.1 - 0.011 15.9 0.1 0.044 13.9 0.0 1.9 1 1 0 2 2 2 0 Novel AID APOBEC clade 1 XOO_2897-deam PF14440.6 KXG53512.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase DnaJ_C PF01556.18 KXG53513.1 - 6.2e-39 133.4 0.4 8.2e-39 133.1 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXG53513.1 - 3.2e-26 91.2 0.9 5.3e-26 90.5 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXG53513.1 - 3.3e-15 56.2 19.4 5.8e-15 55.4 19.4 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KXG53513.1 - 1.1 9.3 9.7 0.53 10.3 2.5 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SET PF00856.28 KXG53514.1 - 2.9e-12 47.3 0.1 4.3e-11 43.5 0.0 2.5 2 1 0 2 2 2 1 SET domain Sulfate_transp PF00916.20 KXG53515.1 - 7.4e-111 370.6 20.6 1e-110 370.1 20.6 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXG53515.1 - 2.8e-08 33.4 0.0 5.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KXG53515.1 - 0.00036 20.9 2.7 0.00036 20.9 2.7 3.5 2 1 1 3 3 3 2 Molybdate transporter of MFS superfamily Pantoate_transf PF02548.15 KXG53516.1 - 1.8e-105 352.0 0.8 2.1e-105 351.8 0.8 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KXG53516.1 - 3.7e-07 29.8 1.4 1.9e-06 27.5 1.4 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Mg_chelatase_C PF13335.6 KXG53516.1 - 0.028 15.0 0.0 0.058 14.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal DUF374 PF04028.13 KXG53516.1 - 0.16 11.6 1.5 8 6.1 0.0 3.7 4 2 1 5 5 5 0 Domain of unknown function (DUF374) Rab5ip PF07019.12 KXG53517.1 - 3.1e-20 72.5 9.4 5e-20 71.9 9.4 1.3 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) SAM_2 PF07647.17 KXG53518.1 - 1.3e-08 34.8 0.1 2.7e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXG53518.1 - 0.00039 20.8 0.1 0.00093 19.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 KXG53518.1 - 0.09 13.0 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) TPR_19 PF14559.6 KXG53519.1 - 6.4e-18 65.0 16.1 0.00045 20.7 0.0 7.6 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXG53519.1 - 2e-14 52.8 0.9 0.01 16.2 0.0 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXG53519.1 - 4.7e-12 45.6 19.8 0.00013 22.5 1.2 9.6 8 3 3 11 11 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG53519.1 - 5.7e-12 45.7 15.2 0.035 14.3 1.1 7.6 8 1 1 9 9 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KXG53519.1 - 2.5e-11 44.0 17.0 2e-05 25.1 3.8 5.3 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXG53519.1 - 5.6e-11 41.7 24.4 0.21 11.8 0.2 10.1 12 0 0 12 12 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXG53519.1 - 1.3e-09 37.5 18.1 0.19 12.0 0.1 9.0 11 0 0 11 11 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXG53519.1 - 2.9e-09 36.5 6.8 0.024 14.3 0.2 7.3 6 2 2 8 8 8 2 TPR repeat TPR_1 PF00515.28 KXG53519.1 - 1.9e-07 30.6 21.4 0.82 9.6 0.0 10.0 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXG53519.1 - 7.6e-06 26.1 24.6 0.12 12.7 2.7 7.6 6 3 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXG53519.1 - 0.00012 22.1 10.3 0.00021 21.4 0.4 5.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXG53519.1 - 0.00033 20.5 19.0 2.1 8.5 0.0 8.1 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXG53519.1 - 0.00051 19.4 1.7 12 5.0 0.0 4.5 3 2 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXG53519.1 - 0.00098 19.6 10.2 1.5 9.7 0.0 7.1 7 0 0 7 7 6 1 Tetratricopeptide repeat NARP1 PF12569.8 KXG53519.1 - 0.0085 15.1 4.2 0.47 9.3 0.2 4.0 3 2 1 4 4 4 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 KXG53519.1 - 0.012 15.9 5.3 6.3 7.2 0.1 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 KXG53519.1 - 0.025 13.6 0.0 0.11 11.5 0.0 2.0 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Alkyl_sulf_dimr PF14863.6 KXG53519.1 - 0.056 13.9 0.2 14 6.1 0.0 3.3 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation SNAP PF14938.6 KXG53519.1 - 0.13 11.7 0.5 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP BTAD PF03704.17 KXG53519.1 - 0.15 12.5 3.8 0.56 10.6 0.2 3.5 4 0 0 4 4 3 0 Bacterial transcriptional activator domain TPR_MalT PF17874.1 KXG53519.1 - 0.29 10.4 8.8 5.7 6.2 0.1 4.1 4 2 0 4 4 4 0 MalT-like TPR region PPR PF01535.20 KXG53519.1 - 0.93 9.9 3.6 10 6.6 0.2 4.0 4 0 0 4 4 4 0 PPR repeat TPR_10 PF13374.6 KXG53519.1 - 3.8 7.5 8.5 5.1 7.1 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 KXG53520.1 - 3.5e-27 95.3 43.0 1.2e-23 83.6 33.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG53520.1 - 0.0029 16.1 4.6 0.004 15.6 4.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3336 PF11815.8 KXG53521.1 - 6.7e-47 158.7 2.9 1.1e-46 158.0 2.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KXG53521.1 - 1.8e-16 61.0 0.4 1.2e-15 58.2 0.1 2.4 2 1 0 2 2 2 1 Patatin-like phospholipase LRR_8 PF13855.6 KXG53522.1 - 1.9e-14 53.2 11.7 4.7e-09 35.9 2.2 4.0 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KXG53522.1 - 8.8e-13 48.2 8.9 0.0012 19.2 0.0 5.0 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXG53522.1 - 0.00043 19.8 0.3 0.024 14.1 0.4 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KXG53522.1 - 0.0054 17.1 9.4 18 6.4 0.1 6.4 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 KXG53522.1 - 0.027 14.5 11.8 0.93 9.7 0.5 5.2 5 0 0 5 5 5 0 Leucine Rich repeat Metallophos PF00149.28 KXG53523.1 - 4e-40 138.5 0.1 5.2e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXG53523.1 - 1e-22 80.3 2.4 1.4e-22 79.9 1.5 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Arf PF00025.21 KXG53524.1 - 2.9e-59 199.5 0.0 3.8e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KXG53524.1 - 2.4e-10 40.1 0.0 5.8e-07 29.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KXG53524.1 - 5.7e-08 32.4 0.0 8e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KXG53524.1 - 1.1e-06 28.9 0.0 2.5e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXG53524.1 - 1.1e-06 28.7 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KXG53524.1 - 3.8e-05 23.3 0.0 5.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXG53524.1 - 0.00021 20.7 0.0 0.00025 20.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 KXG53524.1 - 0.14 11.7 0.0 7.9 6.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 KXG53524.1 - 0.15 11.6 0.0 3.4 7.1 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DUF2457 PF10446.9 KXG53525.1 - 3.5e-140 468.2 33.0 3.5e-140 468.2 33.0 3.7 2 2 1 3 3 3 1 Protein of unknown function (DUF2457) Abhydrolase_6 PF12697.7 KXG53526.1 - 9.9e-06 26.3 0.0 1.2e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KXG53526.1 - 0.0044 15.9 0.0 0.0067 15.3 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Senescence PF06911.12 KXG53527.1 - 0.093 13.0 4.4 0.15 12.4 4.4 1.3 1 1 0 1 1 1 0 Senescence-associated protein Cecropin PF00272.19 KXG53527.1 - 0.1 12.3 0.7 0.1 12.3 0.7 1.9 2 0 0 2 2 2 0 Cecropin family VPS13_C PF16909.5 KXG53527.1 - 0.51 10.1 2.6 0.59 9.9 2.2 1.3 1 1 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal AflR PF08493.10 KXG53528.1 - 6.7e-05 22.5 0.3 9.2e-05 22.0 0.3 1.2 1 0 0 1 1 1 1 Aflatoxin regulatory protein Polysacc_deac_1 PF01522.21 KXG53528.1 - 0.086 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide deacetylase Lactamase_B PF00753.27 KXG53529.1 - 2.9e-17 63.3 3.1 3.7e-16 59.7 3.1 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXG53529.1 - 2.8e-06 27.0 0.2 4.6e-06 26.3 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KXG53529.1 - 7.1e-05 22.3 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXG53529.1 - 0.0048 16.8 0.4 0.017 15.0 0.4 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Vezatin PF12632.7 KXG53530.1 - 2.8e-68 230.3 0.1 5e-68 229.5 0.0 1.4 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes PCNA_N PF00705.18 KXG53531.1 - 4.5e-55 184.8 3.5 5.2e-55 184.6 2.2 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KXG53531.1 - 2.5e-51 173.1 0.0 5.8e-51 172.0 0.0 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KXG53531.1 - 2.5e-07 30.4 0.1 3.1e-07 30.1 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KXG53531.1 - 1e-05 24.8 0.4 0.00078 18.6 0.1 2.0 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 KXG53531.1 - 0.00062 19.0 0.3 0.0041 16.3 0.1 2.0 1 1 1 2 2 2 1 Hus1-like protein HRI1 PF16815.5 KXG53532.1 - 1.7e-28 99.9 0.4 8.7e-28 97.6 0.4 1.8 1 1 0 1 1 1 1 Protein HRI1 p450 PF00067.22 KXG53533.1 - 2e-49 168.6 0.0 4.1e-49 167.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_15 PF09445.10 KXG53533.1 - 0.082 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase APH PF01636.23 KXG53534.1 - 1.2e-07 31.9 0.4 1.2e-07 31.9 0.4 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family SCIMP PF15050.6 KXG53535.1 - 0.32 11.5 2.4 0.67 10.4 0.1 2.6 3 0 0 3 3 3 0 SCIMP protein Sec61_beta PF03911.16 KXG53536.1 - 1.6e-17 63.2 0.8 2.2e-17 62.8 0.8 1.2 1 0 0 1 1 1 1 Sec61beta family Abhydrolase_3 PF07859.13 KXG53537.1 - 1.2e-16 61.2 0.0 5.8e-15 55.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXG53537.1 - 9.5e-08 31.8 0.0 8.6e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 KXG53537.1 - 0.077 11.8 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Carboxylesterase family DLH PF01738.18 KXG53537.1 - 0.2 11.2 0.0 0.39 10.2 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family SSF PF00474.17 KXG53539.1 - 2.5e-20 72.7 31.2 4e-20 72.1 31.2 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Dynein_light PF01221.18 KXG53540.1 - 6.1e-36 122.6 1.3 1e-35 121.9 1.3 1.4 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_C3 PF00548.20 KXG53540.1 - 0.001 19.0 0.4 0.01 15.8 0.1 2.0 1 1 1 2 2 2 1 3C cysteine protease (picornain 3C) zinc_ribbon_15 PF17032.5 KXG53540.1 - 0.019 15.7 2.0 0.041 14.6 2.0 1.5 1 0 0 1 1 1 0 zinc-ribbon family UPA_2 PF17809.1 KXG53540.1 - 0.12 12.2 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 UPA domain RRM_1 PF00076.22 KXG53541.1 - 1.3e-75 249.2 1.2 8.4e-19 67.2 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXG53541.1 - 1.4e-08 34.4 0.0 0.062 12.9 0.0 4.5 4 1 1 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXG53541.1 - 8.6e-07 28.9 0.0 1.5 8.9 0.0 3.6 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KXG53541.1 - 2.7e-06 27.1 0.0 0.2 11.5 0.0 4.2 5 0 0 5 5 5 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KXG53541.1 - 7.3e-06 26.0 0.0 0.56 10.4 0.0 3.9 3 0 0 3 3 3 2 RNA recognition motif Limkain-b1 PF11608.8 KXG53541.1 - 0.00022 21.2 0.1 1.4 9.0 0.0 4.7 5 0 0 5 5 5 1 Limkain b1 RRM_3 PF08777.11 KXG53541.1 - 0.014 15.4 1.6 81 3.3 0.0 5.1 4 1 1 5 5 5 0 RNA binding motif TEA PF01285.18 KXG53542.1 - 2e-27 95.1 0.0 4.1e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 TEA/ATTS domain Aldo_ket_red PF00248.21 KXG53543.1 - 3.3e-40 138.1 0.0 4.9e-40 137.5 0.0 1.2 1 1 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_76 PF03663.14 KXG53545.1 - 7.4e-135 450.2 16.7 8.5e-135 450.0 16.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cloacin_immun PF03513.14 KXG53545.1 - 0.0088 16.4 0.1 0.019 15.3 0.1 1.5 1 0 0 1 1 1 1 Cloacin immunity protein TMEM51 PF15345.6 KXG53547.1 - 0.016 15.1 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 DUF5305 PF17231.2 KXG53547.1 - 0.11 11.9 0.3 0.15 11.5 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) p450 PF00067.22 KXG53548.1 - 1.8e-23 83.1 0.0 3.2e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KXG53548.1 - 1.8e-14 53.8 0.0 3.4e-14 52.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXG53548.1 - 0.00017 21.8 0.1 0.00035 20.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXG53548.1 - 0.0006 19.0 0.0 0.0031 16.6 0.0 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.24 KXG53548.1 - 0.0013 18.1 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KXG53548.1 - 0.0017 17.7 0.1 0.0094 15.2 0.1 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG53548.1 - 0.0083 16.7 0.4 0.06 13.9 0.2 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXG53548.1 - 0.01 14.8 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 KXG53548.1 - 0.028 13.7 0.0 0.084 12.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2204 PF09970.9 KXG53548.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) TPR_10 PF13374.6 KXG53549.1 - 5.5e-37 124.6 15.5 4.3e-09 36.0 0.2 6.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXG53549.1 - 7.8e-36 122.2 17.0 8e-17 61.3 2.0 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat FAD_binding_4 PF01565.23 KXG53549.1 - 1e-29 103.1 2.9 2.2e-29 102.0 2.9 1.6 1 0 0 1 1 1 1 FAD binding domain TPR_1 PF00515.28 KXG53549.1 - 2.6e-26 90.3 10.8 7.2e-05 22.4 0.4 5.7 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 KXG53549.1 - 4.1e-19 67.1 15.0 0.00089 19.1 0.2 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXG53549.1 - 3.2e-18 64.3 12.5 0.0039 17.2 0.3 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXG53549.1 - 1.3e-15 56.2 8.0 0.0038 17.3 0.1 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KXG53549.1 - 2.3e-12 47.0 6.3 6e-12 45.6 6.2 1.8 1 1 0 1 1 1 1 MalT-like TPR region TPR_14 PF13428.6 KXG53549.1 - 3e-11 43.2 13.7 0.11 13.4 0.2 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXG53549.1 - 2.1e-08 34.6 13.5 0.27 11.9 1.2 5.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXG53549.1 - 2e-07 31.4 3.3 0.014 15.9 0.2 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat NB-ARC PF00931.22 KXG53549.1 - 4.1e-07 29.4 0.0 0.011 15.0 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain PNP_UDP_1 PF01048.20 KXG53549.1 - 5.3e-06 25.9 0.1 1.5e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily BBE PF08031.12 KXG53549.1 - 6.1e-06 26.3 0.9 1.4e-05 25.1 0.9 1.6 1 0 0 1 1 1 1 Berberine and berberine like TPR_4 PF07721.14 KXG53549.1 - 1.9e-05 24.9 9.3 0.84 10.4 0.1 5.2 5 0 0 5 5 4 3 Tetratricopeptide repeat AAA_16 PF13191.6 KXG53549.1 - 2.9e-05 24.5 0.0 8.2e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF2225 PF09986.9 KXG53549.1 - 0.014 15.2 2.7 0.92 9.2 0.4 2.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_17 PF13431.6 KXG53549.1 - 0.016 15.5 12.6 2.6 8.6 0.1 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat ATPase_2 PF01637.18 KXG53549.1 - 0.024 14.5 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_6 PF13174.6 KXG53549.1 - 0.11 13.2 16.1 11 6.9 0.3 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN6_N PF18055.1 KXG53549.1 - 0.11 12.9 1.5 4 7.8 0.1 3.1 2 1 1 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF4810 PF16068.5 KXG53549.1 - 0.12 12.9 3.9 36 5.0 0.1 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4810) TPR_11 PF13414.6 KXG53549.1 - 0.34 10.6 12.3 1.4 8.7 0.2 5.2 5 0 0 5 5 5 0 TPR repeat DUF3726 PF12525.8 KXG53549.1 - 1.4 9.1 4.1 35 4.6 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3726) TPR_3 PF07720.12 KXG53549.1 - 1.6 8.8 10.0 1.4 9.0 0.0 4.5 6 0 0 6 6 3 0 Tetratricopeptide repeat AMP-binding PF00501.28 KXG53550.1 - 4.5e-67 226.5 0.0 3.9e-66 223.4 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KXG53550.1 - 3.5e-59 200.0 0.0 1.4e-58 198.1 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 KXG53550.1 - 3.3e-11 43.4 0.6 8.2e-11 42.1 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXG53550.1 - 3.3e-10 40.8 0.0 9.2e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 KXG53550.1 - 1.3e-08 34.6 0.0 2.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXG53550.1 - 4.4e-06 25.9 0.0 8.4e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXG53550.1 - 0.00069 19.1 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXG53550.1 - 0.011 15.0 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LRR_4 PF12799.7 KXG53551.1 - 1.6e-38 130.0 42.7 2.4e-08 34.1 0.8 6.8 2 1 6 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXG53551.1 - 8.3e-22 76.7 31.8 2.6e-06 27.1 2.4 6.3 2 1 5 7 7 7 7 Leucine rich repeat LRR_9 PF14580.6 KXG53551.1 - 2.8e-16 59.5 14.0 9.1e-08 31.8 1.9 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KXG53551.1 - 3.3e-06 26.7 18.3 0.18 11.9 0.3 7.5 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.33 KXG53551.1 - 1.1e-05 25.3 23.5 9.5 7.2 0.4 9.7 10 0 0 10 10 10 2 Leucine Rich Repeat NIF PF03031.18 KXG53552.1 - 2e-54 183.6 0.1 3e-54 183.0 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ABC_membrane_2 PF06472.15 KXG53553.1 - 8.9e-87 290.9 0.3 1.8e-86 289.9 0.0 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KXG53553.1 - 6.4e-12 46.2 0.0 1.2e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter THOC7 PF05615.13 KXG53553.1 - 0.0062 16.8 0.3 0.012 15.9 0.3 1.4 1 0 0 1 1 1 1 Tho complex subunit 7 AAA_23 PF13476.6 KXG53553.1 - 0.022 15.3 1.0 2.5 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXG53553.1 - 0.11 12.2 0.0 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Clr2 PF10383.9 KXG53554.1 - 1.3e-29 103.9 0.0 2.4e-29 103.0 0.0 1.5 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 Gpr1_Fun34_YaaH PF01184.19 KXG53555.1 - 2.6e-85 285.2 16.0 3.1e-85 285.0 16.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family tRNA-synt_2 PF00152.20 KXG53556.1 - 1.6e-62 211.4 0.0 2.1e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXG53556.1 - 1.8e-08 34.3 0.0 3.5e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXG53556.1 - 3.6e-06 26.6 0.0 0.0029 17.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) 2OG-FeII_Oxy PF03171.20 KXG53556.1 - 0.064 13.7 0.0 0.17 12.4 0.0 1.9 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily zf-Tim10_DDP PF02953.15 KXG53557.1 - 5.1e-23 80.5 0.8 6.1e-23 80.2 0.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF1287 PF06940.11 KXG53557.1 - 0.17 11.5 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) Tom5 PF10642.9 KXG53557.1 - 0.46 10.6 0.1 0.46 10.6 0.1 1.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Trypan_PARP PF05887.11 KXG53558.1 - 2.5 8.1 8.5 4.9 7.1 8.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4953 PF16313.5 KXG53560.1 - 0.012 14.9 0.1 0.014 14.6 0.1 1.2 1 0 0 1 1 1 0 Met-zincin FlbD PF06289.11 KXG53560.1 - 0.27 10.9 1.4 0.57 9.8 0.4 2.0 3 0 0 3 3 3 0 Flagellar and Swarming motility proteins DUF3881 PF12997.7 KXG53561.1 - 0.16 11.2 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) Frag1 PF10277.9 KXG53563.1 - 6.6e-33 114.1 16.0 7.6e-33 113.9 16.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family EVC2_like PF12297.8 KXG53563.1 - 0.79 8.3 1.9 1.2 7.8 1.9 1.3 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein CLTH PF10607.9 KXG53564.1 - 9.6e-31 106.7 0.0 1.7e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KXG53564.1 - 5.4e-08 32.7 0.1 1e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KXG53564.1 - 0.00017 21.0 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 KXG53564.1 - 0.00026 20.9 0.1 0.00044 20.1 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXG53564.1 - 0.0011 19.3 0.3 0.0019 18.5 0.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXG53564.1 - 0.0037 17.1 0.8 0.0068 16.2 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXG53564.1 - 0.012 15.5 0.3 0.021 14.7 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXG53564.1 - 0.016 15.1 0.7 0.029 14.2 0.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KXG53564.1 - 0.028 14.3 0.4 0.05 13.5 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FAP206 PF12018.8 KXG53564.1 - 0.12 11.8 0.0 0.26 10.8 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function BTB PF00651.31 KXG53565.1 - 0.00055 20.1 0.0 0.003 17.8 0.0 2.1 3 0 0 3 3 3 1 BTB/POZ domain PCI PF01399.27 KXG53566.1 - 1.8e-10 41.3 0.0 3.3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 PCI domain Ribosomal_L18A PF01775.17 KXG53567.1 - 7.1e-54 181.1 0.2 8.6e-54 180.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A CysA_C_terminal PF17850.1 KXG53567.1 - 0.079 13.5 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 CysA C-terminal regulatory domain NAD_binding_1 PF00175.21 KXG53568.1 - 4.6e-34 117.4 0.0 6.8e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXG53568.1 - 4.7e-22 78.2 0.0 1e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXG53568.1 - 3.3e-09 37.0 0.0 1.7e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain HMG_box PF00505.19 KXG53569.1 - 1.3e-10 41.5 3.1 2.8e-10 40.5 3.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXG53569.1 - 4.3e-06 27.2 4.5 1.2e-05 25.8 3.6 2.2 2 0 0 2 2 2 1 HMG-box domain Peptidase_M61 PF05299.12 KXG53569.1 - 0.1 13.0 0.6 0.32 11.4 0.6 1.8 1 0 0 1 1 1 0 M61 glycyl aminopeptidase Herpes_UL25 PF01499.16 KXG53569.1 - 1.4 7.4 7.7 1.9 6.9 7.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Amidohydro_1 PF01979.20 KXG53570.1 - 2e-77 260.9 2.0 4.2e-77 259.8 1.1 1.8 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.20 KXG53570.1 - 1.1e-56 190.3 0.8 4e-56 188.6 0.3 2.1 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KXG53570.1 - 7.8e-40 134.9 0.1 3e-39 133.0 0.0 2.0 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 KXG53570.1 - 2.5e-38 130.3 0.4 1.7e-37 127.7 0.1 2.3 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KXG53570.1 - 3.5e-09 36.6 0.2 3.9e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 KXG53570.1 - 0.017 14.9 0.0 0.061 13.1 0.0 2.0 1 0 0 1 1 1 0 Amidohydrolase BORCS6 PF10157.9 KXG53571.1 - 0.017 15.3 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 Lactamase_B_2 PF12706.7 KXG53572.1 - 2.8e-08 33.5 0.0 9.9e-08 31.7 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KXG53572.1 - 1e-05 25.7 0.1 4.8e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase RHH_7 PF16777.5 KXG53573.1 - 0.026 14.9 0.1 0.05 14.0 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator, RHH-like, CopG NPR2 PF06218.11 KXG53574.1 - 5e-134 447.4 0.0 4.4e-133 444.2 0.0 2.1 1 1 0 1 1 1 1 Nitrogen permease regulator 2 Ada3 PF10198.9 KXG53575.1 - 4.9e-47 159.4 0.1 4.9e-47 159.4 0.1 2.0 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Ribosomal_L15e PF00827.17 KXG53576.1 - 7.6e-86 286.7 12.4 1.1e-85 286.2 12.4 1.2 1 0 0 1 1 1 1 Ribosomal L15 Orf78 PF06024.12 KXG53576.1 - 0.0097 16.2 0.0 0.034 14.4 0.0 1.9 1 0 0 1 1 1 1 Orf78 (ac78) HECT PF00632.25 KXG53577.1 - 4.2e-72 243.2 0.0 5.4e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MAPEG PF01124.18 KXG53578.1 - 2.1e-17 63.3 2.6 3.1e-17 62.7 2.6 1.2 1 0 0 1 1 1 1 MAPEG family DAO PF01266.24 KXG53579.1 - 6.7e-50 170.6 0.2 8.6e-50 170.3 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fungal_trans PF04082.18 KXG53582.1 - 6.7e-13 48.3 0.2 1.6e-12 47.1 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain RAI16-like PF10257.9 KXG53582.1 - 0.15 10.9 0.0 0.34 9.8 0.0 1.5 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein FMO-like PF00743.19 KXG53584.1 - 9.5e-12 44.1 0.4 2.2e-11 42.9 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXG53584.1 - 2.4e-10 40.5 0.0 5.4e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG53584.1 - 8.8e-07 28.4 0.0 2.4e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG53584.1 - 8.9e-05 21.9 0.0 0.0011 18.3 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG53584.1 - 0.0027 16.9 0.0 0.29 10.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXG53584.1 - 0.0032 17.5 0.0 0.035 14.1 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KXG53584.1 - 0.019 14.6 0.0 0.78 9.2 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KXG53584.1 - 0.09 12.8 0.0 1.1 9.3 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KXG53584.1 - 0.21 10.8 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Fungal_trans PF04082.18 KXG53585.1 - 4.7e-18 65.2 0.0 7.9e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRM_1 PF00076.22 KXG53587.1 - 1.1e-79 262.2 6.3 1.9e-20 72.4 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KXG53587.1 - 6.7e-29 99.9 0.5 5.4e-28 97.0 0.7 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KXG53587.1 - 1.6e-12 47.1 0.3 0.0072 15.9 0.0 5.1 3 2 2 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXG53587.1 - 9.3e-06 25.6 1.6 1.1 9.4 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KXG53587.1 - 2.1e-05 24.5 0.6 6.7 6.9 0.0 5.5 5 1 0 5 5 5 1 RNA recognition motif CbiG_mid PF11761.8 KXG53587.1 - 0.00029 20.9 0.0 3.6 7.8 0.0 3.7 3 0 0 3 3 3 1 Cobalamin biosynthesis central region RRM_occluded PF16842.5 KXG53587.1 - 0.029 14.2 0.1 15 5.5 0.0 3.3 3 0 0 3 3 3 0 Occluded RNA-recognition motif YflT PF11181.8 KXG53587.1 - 0.12 12.9 10.5 0.1 13.1 1.1 3.1 3 0 0 3 3 3 0 Heat induced stress protein YflT CSD PF00313.22 KXG53587.1 - 0.15 11.9 2.8 37 4.3 0.0 3.5 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KXG53587.1 - 0.38 10.5 3.6 14 5.5 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain HECT PF00632.25 KXG53588.1 - 9.2e-85 284.8 0.0 8.3e-84 281.7 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KXG53588.1 - 0.1 12.4 0.6 0.38 10.7 0.6 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif MRP-L27 PF09809.9 KXG53589.1 - 0.016 15.0 1.2 0.051 13.4 1.2 1.9 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L27 GRA6 PF05084.13 KXG53589.1 - 0.18 11.7 0.3 0.25 11.3 0.3 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Utp14 PF04615.13 KXG53590.1 - 1.9e-209 698.0 82.1 1.9e-209 698.0 82.1 2.6 1 1 2 3 3 3 1 Utp14 protein Herpes_LMP2 PF07415.11 KXG53590.1 - 0.074 11.8 0.8 0.11 11.3 0.8 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Glyco_hydro81C PF17652.1 KXG53591.1 - 4.3e-168 559.0 7.0 5.4e-168 558.7 7.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KXG53591.1 - 3.9e-114 381.2 1.1 6.3e-114 380.5 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Metallophos PF00149.28 KXG53592.1 - 1.5e-07 32.1 0.0 4.2e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXG53592.1 - 1e-06 29.0 0.0 0.00067 19.9 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Transp_inhibit PF18791.1 KXG53592.1 - 0.16 11.5 0.2 0.46 10.0 0.0 1.8 2 0 0 2 2 2 0 Transport inhibitor response 1 protein domain Ribosomal_S8e PF01201.22 KXG53593.1 - 6.5e-54 181.8 0.7 7.4e-54 181.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e DUF2470 PF10615.9 KXG53594.1 - 2.8e-18 66.3 0.0 4.2e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) HUN PF08729.10 KXG53595.1 - 0.0018 18.2 3.0 0.0018 18.2 3.0 2.6 2 1 0 2 2 2 1 HPC2 and ubinuclein domain TFIIF_alpha PF05793.12 KXG53595.1 - 0.063 11.9 17.3 0.077 11.6 17.3 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.6 KXG53595.1 - 0.13 12.7 22.1 0.094 13.1 5.6 2.2 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Presenilin PF01080.17 KXG53596.1 - 0.73 8.5 9.5 0.74 8.5 9.5 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KXG53596.1 - 2.9 7.0 3.6 2.8 7.1 3.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.9 KXG53596.1 - 3 6.6 6.2 3.1 6.6 6.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4551 PF15087.6 KXG53596.1 - 4.8 5.9 11.8 5.4 5.7 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SPX PF03105.19 KXG53597.1 - 4.1e-37 129.0 0.2 6e-25 89.0 0.0 2.2 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 KXG53597.1 - 6.2e-32 111.2 41.2 8.6e-32 110.8 41.2 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KXG53597.1 - 1.4e-23 83.6 72.6 3.8e-22 78.8 42.5 2.3 2 1 1 3 3 3 2 Citrate transporter DUF4220 PF13968.6 KXG53597.1 - 1.1 8.6 7.3 0.058 12.8 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) Ribosomal_S7 PF00177.21 KXG53598.1 - 1.5e-26 92.8 0.0 2.8e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF1687 PF07955.11 KXG53598.1 - 0.09 13.3 0.4 0.25 11.8 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1687) Na_Ca_ex PF01699.24 KXG53599.1 - 7.1e-43 146.2 34.3 4.1e-22 78.8 16.2 2.3 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF3671 PF12420.8 KXG53599.1 - 4.6 7.3 5.2 2.8 8.1 0.8 3.1 3 2 0 3 3 3 0 Protein of unknown function DOCK_N PF16172.5 KXG53600.1 - 4.5e-114 381.3 0.0 8.8e-114 380.3 0.0 1.5 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 KXG53600.1 - 2.2e-41 142.1 1.1 1.1e-40 139.8 1.1 1.9 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KXG53600.1 - 3.2e-37 128.3 0.0 5.8e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 KXG53600.1 - 2.1e-05 24.0 0.0 4.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXG53600.1 - 3.7e-05 23.5 0.0 0.00031 20.6 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KXG53600.1 - 0.041 13.6 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain PI3K_C2 PF00792.24 KXG53600.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 Sec3_C PF09763.9 KXG53601.1 - 6.7e-225 748.7 0.0 9.1e-225 748.2 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KXG53601.1 - 9.7e-30 102.6 0.0 1.9e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 KXG53601.1 - 0.0029 17.9 0.2 0.0079 16.5 0.2 1.7 1 0 0 1 1 1 1 Sec3 exocyst complex subunit Ribosomal_L22 PF00237.19 KXG53601.1 - 0.07 13.4 0.1 2.2 8.5 0.0 2.8 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e SRP40_C PF05022.12 KXG53602.1 - 2.3e-16 60.4 0.9 6.7e-16 58.9 0.1 2.2 2 0 0 2 2 2 1 SRP40, C-terminal domain F-box-like PF12937.7 KXG53603.1 - 1.3e-05 25.0 0.1 7.5e-05 22.5 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXG53603.1 - 0.012 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 F-box domain p450 PF00067.22 KXG53604.1 - 1e-42 146.5 0.0 1.8e-42 145.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Pneumo_ncap PF03246.13 KXG53604.1 - 0.19 10.5 0.1 0.47 9.2 0.1 1.5 2 0 0 2 2 2 0 Pneumovirus nucleocapsid protein DUF1992 PF09350.10 KXG53606.1 - 3.8e-18 65.4 0.1 9.7e-18 64.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Spectrin PF00435.21 KXG53606.1 - 0.062 13.8 0.3 0.2 12.2 0.3 1.8 1 0 0 1 1 1 0 Spectrin repeat DUF4884 PF16225.5 KXG53607.1 - 0.09 12.9 0.2 17 5.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4884) Yip1 PF04893.17 KXG53608.1 - 0.075 12.7 0.3 0.11 12.2 0.3 1.2 1 0 0 1 1 1 0 Yip1 domain Herpes_gE PF02480.16 KXG53608.1 - 0.094 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CcmD PF04995.14 KXG53608.1 - 0.7 10.0 5.5 0.82 9.8 2.2 2.5 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Pkinase PF00069.25 KXG53609.1 - 1.4e-16 60.7 0.0 1.8e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXG53609.1 - 1.2e-07 31.3 0.2 1.9e-07 30.7 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXG53609.1 - 1.8e-06 28.0 0.1 2.1e-06 27.8 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXG53609.1 - 2e-06 27.3 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 KXG53609.1 - 2e-05 24.0 0.0 3.5e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXG53609.1 - 0.00033 19.6 0.6 0.00071 18.5 0.5 1.4 1 1 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KXG53609.1 - 0.00081 19.0 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KXG53609.1 - 0.0012 18.4 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 KXG53609.1 - 0.027 13.5 0.1 0.04 13.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PIP49_C PF12260.8 KXG53609.1 - 0.067 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 WD40 PF00400.32 KXG53610.1 - 5.4e-91 296.0 26.7 1.3e-09 38.5 0.3 11.4 11 1 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG53610.1 - 3.7e-37 126.5 0.0 2.9e-06 27.5 0.0 9.7 2 2 8 10 10 10 10 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXG53610.1 - 5.9e-15 54.8 2.5 0.35 10.9 0.0 9.2 11 0 0 11 11 11 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXG53610.1 - 2.7e-13 49.6 0.6 0.28 10.1 0.0 8.3 4 2 5 9 9 9 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KXG53610.1 - 1.3e-09 38.0 2.8 0.0031 17.1 0.1 5.0 2 2 0 3 3 3 2 PQQ-like domain WD40_like PF17005.5 KXG53610.1 - 1.6e-05 24.4 0.0 0.14 11.5 0.0 4.4 3 2 2 6 6 6 1 WD40-like domain Ret2_MD PF18528.1 KXG53610.1 - 2.4e-05 24.6 0.0 2.1 8.8 0.0 5.6 6 2 1 7 7 6 1 RNA editing 3' terminal uridylyl transferase 2 middle domain Nup160 PF11715.8 KXG53610.1 - 2.6e-05 23.1 4.7 0.8 8.3 0.1 6.7 1 1 5 8 8 8 1 Nucleoporin Nup120/160 DUF4596 PF15363.6 KXG53610.1 - 0.00024 21.3 3.5 8.3 6.7 0.0 6.5 8 0 0 8 8 8 1 Domain of unknown function (DUF4596) SRF-TF PF00319.18 KXG53610.1 - 0.00079 18.9 5.7 9 5.9 0.0 6.9 8 0 0 8 8 8 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Me-amine-dh_H PF06433.11 KXG53610.1 - 0.0035 16.3 0.0 0.5 9.2 0.0 3.1 2 1 1 3 3 3 1 Methylamine dehydrogenase heavy chain (MADH) Nbas_N PF15492.6 KXG53610.1 - 0.005 16.2 0.8 11 5.2 0.0 5.1 3 2 3 6 6 6 0 Neuroblastoma-amplified sequence, N terminal DUF5122 PF17164.4 KXG53610.1 - 0.02 15.2 2.3 35 4.8 0.0 5.3 7 0 0 7 7 6 0 Domain of unknown function (DUF5122) beta-propeller Stimulus_sens_1 PF13756.6 KXG53610.1 - 0.033 14.8 0.0 5.3 7.7 0.0 3.7 4 0 0 4 4 4 0 Stimulus-sensing domain RAB3GAP2_N PF14655.6 KXG53610.1 - 0.046 13.0 0.0 18 4.4 0.0 4.2 4 1 2 6 6 6 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ELYS-bb PF16687.5 KXG53610.1 - 0.073 11.7 0.0 11 4.5 0.0 2.9 3 0 0 3 3 3 0 beta-propeller of ELYS nucleoporin Proteasome_A_N PF10584.9 KXG53610.1 - 0.1 12.3 16.1 6.1 6.6 0.1 7.6 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature HPS3_N PF14761.6 KXG53610.1 - 0.16 11.5 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 P5CR_dimer PF14748.6 KXG53611.1 - 3.7e-20 72.1 0.1 1.6e-19 70.1 0.0 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KXG53611.1 - 2.3e-15 56.9 0.3 6e-15 55.6 0.3 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KXG53611.1 - 0.017 15.3 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Histidinol_dh PF00815.20 KXG53611.1 - 0.13 11.3 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Histidinol dehydrogenase ApbA PF02558.16 KXG53611.1 - 0.22 11.2 0.9 0.64 9.7 0.9 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA OCD_Mu_crystall PF02423.15 KXG53612.1 - 6e-14 51.7 0.0 1.8e-11 43.6 0.0 3.3 2 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KXG53612.1 - 1.1e-07 31.9 0.0 4.7e-06 26.7 0.0 2.5 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DUF3530 PF12048.8 KXG53612.1 - 0.038 13.4 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Sacchrp_dh_NADP PF03435.18 KXG53612.1 - 0.062 13.6 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Acetyltransf_8 PF13523.6 KXG53613.1 - 2.2e-50 170.1 0.0 3.1e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain BTB PF00651.31 KXG53614.1 - 1e-10 41.8 0.0 1.8e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Cyclin_N PF00134.23 KXG53616.1 - 1.8e-12 47.1 0.0 6.9e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 KXG53616.1 - 3.5e-07 30.7 0.0 9e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Cyclin Glyco_hydro_12 PF01670.16 KXG53617.1 - 4.5e-46 157.5 6.4 5.2e-46 157.3 6.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Phage_int_SAM_1 PF02899.17 KXG53617.1 - 0.15 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain ERG2_Sigma1R PF04622.12 KXG53618.1 - 1.6e-97 324.9 0.2 1.9e-97 324.7 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein UCR_6-4kD PF08997.10 KXG53618.1 - 0.09 12.7 0.3 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein OTT_1508_deam PF14441.6 KXG53619.1 - 5e-19 68.1 3.7 1.1e-18 66.9 3.7 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase Amidohydro_2 PF04909.14 KXG53620.1 - 4.8e-34 118.5 0.0 6.1e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KXG53620.1 - 0.0054 16.1 0.0 0.011 15.1 0.0 1.5 2 0 0 2 2 2 1 TatD related DNase ApbA PF02558.16 KXG53621.1 - 3.8e-29 101.3 0.0 5.1e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXG53621.1 - 1.1e-25 90.3 0.0 1.6e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal PglD_N PF17836.1 KXG53621.1 - 0.019 15.6 0.0 0.039 14.6 0.0 1.5 1 0 0 1 1 1 0 PglD N-terminal domain ThiF PF00899.21 KXG53621.1 - 0.075 12.4 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.6 KXG53621.1 - 0.093 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Baculo_F PF12259.8 KXG53622.1 - 0.046 12.2 0.0 0.049 12.2 0.0 1.1 1 0 0 1 1 1 0 Baculovirus F protein UPF0060 PF02694.15 KXG53622.1 - 0.096 12.9 0.6 0.36 11.1 0.2 1.9 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family MFS_1 PF07690.16 KXG53623.1 - 1.4e-30 106.5 28.0 1.4e-30 106.5 28.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.25 KXG53625.1 - 7.2e-36 123.5 0.0 9.7e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG53625.1 - 8.9e-26 90.9 0.0 1.3e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG53625.1 - 4.5e-06 26.7 0.1 1.3e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXG53625.1 - 0.00039 20.0 0.1 0.00057 19.4 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXG53625.1 - 0.0047 16.8 0.1 0.0076 16.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXG53625.1 - 0.0054 17.0 0.0 0.0089 16.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Transferase PF02458.15 KXG53626.1 - 9.8e-05 21.2 0.0 0.00043 19.0 0.0 1.8 1 1 0 1 1 1 1 Transferase family NAD_binding_4 PF07993.12 KXG53627.1 - 5.9e-19 68.2 0.0 8.4e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KXG53627.1 - 0.00091 18.7 0.1 0.026 14.0 0.1 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 KXG53628.1 - 1.1e-20 74.1 0.0 1.3e-20 73.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG53628.1 - 3.2e-10 39.7 0.0 3.6e-10 39.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXG53628.1 - 6.9e-05 22.9 0.2 9.4e-05 22.4 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXG53628.1 - 0.00095 18.8 0.0 0.0018 17.9 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 KXG53628.1 - 0.025 14.1 0.0 0.035 13.7 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase ATP_bind_3 PF01171.20 KXG53629.1 - 1.8e-19 70.2 0.0 2.9e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KXG53629.1 - 9.4e-18 63.4 2.3 9.4e-18 63.4 2.3 3.7 4 0 0 4 4 4 1 Zinc-ribbon RecR PF02132.15 KXG53629.1 - 0.0023 17.5 4.1 0.0023 17.5 4.1 2.6 3 0 0 3 3 3 1 RecR protein tRNA_Me_trans PF03054.16 KXG53629.1 - 0.038 12.8 0.0 0.061 12.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.20 KXG53629.1 - 0.55 10.4 5.5 5.5 7.2 0.6 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) RasGEF PF00617.19 KXG53630.1 - 1.6e-43 149.0 0.8 3e-43 148.1 0.8 1.5 1 0 0 1 1 1 1 RasGEF domain Complex1_LYR_2 PF13233.6 KXG53630.1 - 9.1e-20 71.2 0.2 9.1e-20 71.2 0.2 2.1 3 0 0 3 3 3 1 Complex1_LYR-like RasGEF_N PF00618.20 KXG53630.1 - 1.1e-13 51.4 0.0 4.4e-13 49.4 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif DEC-1_N PF04625.13 KXG53631.1 - 0.0067 15.5 0.6 0.0082 15.2 0.6 1.1 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region Nfu_N PF08712.11 KXG53632.1 - 8.3e-32 109.1 0.1 1.4e-30 105.2 0.0 2.3 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KXG53632.1 - 4.9e-28 97.1 0.2 9.1e-28 96.2 0.2 1.5 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 KXG53632.1 - 0.23 11.6 0.4 1.1 9.4 0.3 2.1 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus PSP1 PF04468.12 KXG53633.1 - 4.5e-28 97.3 2.6 7.3e-28 96.7 2.6 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region FRG1 PF06229.12 KXG53634.1 - 1.5e-51 174.8 0.1 2.2e-51 174.3 0.1 1.2 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 KXG53634.1 - 0.031 14.5 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 Fascin domain Arc_PepC PF06819.11 KXG53634.1 - 0.041 14.0 0.3 0.071 13.2 0.3 1.4 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain Frataxin_Cyay PF01491.16 KXG53634.1 - 0.063 13.4 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Frataxin-like domain Beta-lactamase PF00144.24 KXG53635.1 - 3.2e-55 187.7 0.0 4.6e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KXG53635.1 - 2.4e-15 56.9 0.0 4.3e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) ADH_N PF08240.12 KXG53636.1 - 1.2e-34 118.4 1.9 2.3e-34 117.5 1.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG53636.1 - 2.9e-16 59.7 0.0 5.3e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXG53636.1 - 5.6e-16 58.7 0.0 8.5e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXG53636.1 - 2.3e-06 28.7 0.0 4.6e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KXG53636.1 - 0.00074 18.9 0.8 0.0011 18.3 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KXG53636.1 - 0.0018 18.7 0.0 0.0036 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KXG53636.1 - 0.027 13.7 0.3 0.1 11.8 0.2 1.8 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXG53636.1 - 0.038 14.2 0.1 0.085 13.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF2318 PF10080.9 KXG53636.1 - 0.041 14.0 0.9 9.5 6.4 0.2 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) NAD_binding_3 PF03447.16 KXG53636.1 - 0.068 13.8 0.0 0.18 12.4 0.0 1.7 2 0 0 2 2 1 0 Homoserine dehydrogenase, NAD binding domain Thi4 PF01946.17 KXG53636.1 - 0.08 12.2 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.20 KXG53636.1 - 0.1 12.7 0.0 0.34 11.0 0.0 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KXG53636.1 - 0.11 11.6 0.5 0.15 11.1 0.5 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 KXG53636.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KXG53636.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Staph_opine_DH PF10100.9 KXG53636.1 - 0.22 10.1 0.0 0.35 9.4 0.0 1.3 1 1 0 1 1 1 0 Staphylopine dehydrogenase Vps52 PF04129.12 KXG53637.1 - 3.4e-118 395.6 0.0 4e-118 395.4 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KXG53637.1 - 1.7e-06 26.8 0.0 2.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 THOC7 PF05615.13 KXG53637.1 - 0.0018 18.5 0.8 0.0042 17.4 0.3 1.8 2 0 0 2 2 2 1 Tho complex subunit 7 Sec8_exocyst PF04048.14 KXG53637.1 - 0.11 12.3 2.1 0.17 11.8 0.2 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain eIF-5a PF01287.20 KXG53638.1 - 3.1e-28 97.7 1.6 4.3e-28 97.2 1.6 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Nitro_FeMo-Co PF02579.17 KXG53638.1 - 0.0047 17.2 0.0 0.01 16.2 0.0 1.6 2 0 0 2 2 2 1 Dinitrogenase iron-molybdenum cofactor EFP_N PF08207.12 KXG53638.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain ubiquitin PF00240.23 KXG53639.1 - 1.6e-32 111.0 0.7 3.5e-32 110.0 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 KXG53639.1 - 2.3e-29 101.0 10.8 4e-29 100.3 10.8 1.4 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 KXG53639.1 - 3.1e-14 52.6 1.0 8.8e-14 51.1 1.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXG53639.1 - 0.00028 21.3 0.1 0.00071 20.0 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KXG53639.1 - 0.031 14.2 0.2 0.085 12.8 0.0 1.8 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KXG53639.1 - 0.097 13.0 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Yip1 PF04893.17 KXG53640.1 - 2.1e-16 60.1 13.1 2.1e-16 60.1 13.1 1.4 1 1 0 1 1 1 1 Yip1 domain RabGAP-TBC PF00566.18 KXG53641.1 - 8.6e-26 90.9 0.2 1.2e-25 90.4 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMS1_N PF10433.9 KXG53642.1 - 2e-90 303.8 0.0 3.2e-90 303.1 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KXG53642.1 - 3.8e-05 23.2 0.0 0.00063 19.1 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region PQQ_3 PF13570.6 KXG53642.1 - 0.027 14.9 1.4 16 6.1 0.0 4.2 3 0 0 3 3 3 0 PQQ-like domain GTP_EFTU PF00009.27 KXG53643.1 - 7.3e-34 117.0 0.0 5.2e-33 114.2 0.0 2.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KXG53643.1 - 1.7e-19 69.9 0.1 6.6e-19 68.0 0.1 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KXG53643.1 - 6.7e-10 39.2 5.0 1.2e-09 38.4 0.0 3.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KXG53643.1 - 2.2e-08 33.9 0.2 7.1e-08 32.3 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 KXG53643.1 - 6.4e-07 29.5 0.1 9.6e-06 25.7 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KXG53643.1 - 0.00033 20.9 0.0 0.00091 19.4 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KXG53643.1 - 0.00089 19.1 0.0 0.0028 17.5 0.0 2.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.22 KXG53643.1 - 0.041 13.5 0.0 0.28 10.7 0.0 2.5 2 1 0 2 2 2 0 Ras family RsgA_GTPase PF03193.16 KXG53643.1 - 0.055 13.4 0.4 0.92 9.4 0.3 3.0 2 1 0 2 2 2 0 RsgA GTPase Rhodanese PF00581.20 KXG53644.1 - 2.1e-11 44.3 0.0 3.3e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Speriolin_N PF15058.6 KXG53644.1 - 0.081 13.0 3.4 0.12 12.5 3.4 1.3 1 0 0 1 1 1 0 Speriolin N terminus p450 PF00067.22 KXG53645.1 - 3.1e-54 184.5 0.0 4.2e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SRP68 PF16969.5 KXG53646.1 - 9.7e-196 652.1 3.8 1.1e-195 651.9 3.8 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 PPR_2 PF13041.6 KXG53647.1 - 7.3e-20 70.9 8.0 7.7e-10 38.8 0.0 8.2 9 2 2 11 11 11 3 PPR repeat family PPR PF01535.20 KXG53647.1 - 4.2e-16 58.0 4.8 0.0016 18.5 0.0 9.1 9 0 0 9 9 9 3 PPR repeat PPR_3 PF13812.6 KXG53647.1 - 8.7e-16 57.8 0.0 6.2e-06 26.2 0.0 4.2 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 KXG53647.1 - 1.1e-11 44.2 0.2 0.031 14.0 0.0 5.8 6 0 0 6 6 6 4 PPR repeat PPR_long PF17177.4 KXG53647.1 - 7.6e-08 32.0 0.0 0.013 14.9 0.0 3.6 4 0 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP CitG PF01874.16 KXG53647.1 - 0.12 12.0 0.1 2.2 7.8 0.0 2.5 2 0 0 2 2 2 0 ATP:dephospho-CoA triphosphoribosyl transferase MCM PF00493.23 KXG53648.1 - 4.2e-96 320.4 0.1 6.8e-96 319.7 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXG53648.1 - 1.6e-30 105.6 0.0 4.5e-30 104.1 0.0 1.8 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 KXG53648.1 - 1.5e-23 83.0 0.7 3.4e-23 81.9 0.7 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXG53648.1 - 1.7e-10 41.4 0.0 8.2e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXG53648.1 - 5.1e-06 26.0 0.0 5.5e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXG53648.1 - 0.0056 16.5 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TFIIF_alpha PF05793.12 KXG53648.1 - 2.9 6.4 10.4 4.2 5.8 10.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Peptidase_S32 PF05579.13 KXG53650.1 - 0.0019 17.5 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S64 PF08192.11 KXG53650.1 - 0.054 12.0 0.0 0.074 11.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 GCV_T_C PF08669.11 KXG53650.1 - 0.12 12.3 1.1 0.44 10.5 0.2 2.2 2 1 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain Spo7 PF03907.13 KXG53651.1 - 1.4e-89 299.3 0.0 2.2e-89 298.7 0.0 1.3 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_1 PF00561.20 KXG53652.1 - 8e-19 68.3 0.0 6.1e-17 62.1 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG53652.1 - 6.2e-15 55.1 0.0 3.7e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXG53652.1 - 2e-12 48.2 13.4 8.7e-12 46.1 8.0 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 KXG53652.1 - 2.4e-05 23.8 0.0 4.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KXG53652.1 - 0.00017 21.3 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KXG53652.1 - 0.012 14.5 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KXG53652.1 - 0.025 14.4 0.0 0.2 11.4 0.0 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KXG53652.1 - 0.057 13.3 0.0 0.43 10.4 0.0 2.3 3 0 0 3 3 3 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KXG53652.1 - 0.059 12.4 0.0 0.19 10.7 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase LIDHydrolase PF10230.9 KXG53652.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Thioesterase PF00975.20 KXG53652.1 - 0.15 12.2 0.5 0.59 10.2 0.5 2.0 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 KXG53652.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KXG53652.1 - 0.17 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DMRT-like PF15791.5 KXG53653.1 - 0.18 12.2 0.3 0.18 12.2 0.3 2.8 3 0 0 3 3 3 0 Doublesex-and mab-3-related transcription factor C1 and C2 TatD_DNase PF01026.21 KXG53654.1 - 1.1e-34 119.9 0.0 1.9e-34 119.2 0.0 1.3 1 1 0 1 1 1 1 TatD related DNase DUF3730 PF12530.8 KXG53654.1 - 0.2 11.2 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) Fungal_trans PF04082.18 KXG53655.1 - 1.3e-20 73.5 0.0 3.7e-20 72.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG53655.1 - 4.3e-09 36.4 11.5 6.4e-09 35.8 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GFO_IDH_MocA PF01408.22 KXG53656.1 - 8.4e-19 68.6 0.0 1.7e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CBFD_NFYB_HMF PF00808.23 KXG53657.1 - 2.8e-29 101.2 1.0 3.8e-29 100.8 1.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXG53657.1 - 3.5e-06 27.4 0.0 5.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KXG53657.1 - 0.00078 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KXG53657.1 - 0.0017 18.3 0.1 0.0027 17.7 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 KXG53657.1 - 0.0049 17.0 0.0 0.0068 16.5 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 KXG53657.1 - 0.052 14.0 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.20 KXG53658.1 - 1.7e-24 85.8 8.7 2.2e-24 85.4 8.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF2205 PF10224.9 KXG53658.1 - 0.03 14.3 1.9 0.03 14.3 1.9 1.9 2 0 0 2 2 2 0 Short coiled-coil protein Prefoldin PF02996.17 KXG53658.1 - 0.031 14.2 7.1 0.34 10.8 0.2 2.2 1 1 0 2 2 2 0 Prefoldin subunit UCR_14kD PF02271.16 KXG53658.1 - 0.05 13.6 0.7 0.07 13.1 0.6 1.3 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit ATP-synt_D PF01813.17 KXG53658.1 - 0.05 13.4 2.8 0.87 9.4 0.3 2.0 2 0 0 2 2 2 0 ATP synthase subunit D TACC_C PF05010.14 KXG53658.1 - 0.07 12.9 7.2 0.16 11.7 7.2 1.5 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FliE PF02049.18 KXG53658.1 - 0.072 13.2 3.1 1.8 8.7 0.5 2.1 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE DASH_Dad3 PF08656.10 KXG53658.1 - 0.073 13.2 3.2 0.15 12.2 0.2 2.1 2 1 0 2 2 2 0 DASH complex subunit Dad3 ZnuA PF01297.17 KXG53658.1 - 0.18 11.2 2.6 0.5 9.7 0.6 2.0 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic PI3K_P85_iSH2 PF16454.5 KXG53658.1 - 0.21 11.2 8.5 0.48 10.0 2.3 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain GP41 PF00517.17 KXG53658.1 - 0.43 10.4 4.2 0.91 9.4 0.3 2.0 1 1 1 2 2 2 0 Retroviral envelope protein Wtap PF17098.5 KXG53658.1 - 0.68 9.8 6.0 13 5.7 5.9 2.1 1 1 0 1 1 1 0 WTAP/Mum2p family Fzo_mitofusin PF04799.13 KXG53658.1 - 0.73 9.4 4.7 8.9 5.8 0.7 2.0 1 1 1 2 2 2 0 fzo-like conserved region OmpH PF03938.14 KXG53658.1 - 0.8 10.0 11.2 2.8 8.3 4.5 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HA2 PF04408.23 KXG53659.1 - 4.4e-19 68.8 0.0 4.4e-19 68.8 0.0 2.6 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXG53659.1 - 3e-18 65.9 0.0 9.6e-18 64.3 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXG53659.1 - 4.7e-15 55.9 0.0 1.4e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXG53659.1 - 1.5e-07 31.3 0.1 4.6e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXG53659.1 - 3.9e-05 24.0 0.1 0.0001 22.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXG53659.1 - 0.0011 18.7 0.0 0.0025 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXG53659.1 - 0.0012 19.1 0.1 0.003 17.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXG53659.1 - 0.0045 16.1 0.0 0.012 14.7 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 KXG53659.1 - 0.0088 16.1 0.0 0.057 13.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KXG53659.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain SRP54 PF00448.22 KXG53659.1 - 0.014 15.0 0.2 0.062 12.9 0.2 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 KXG53659.1 - 0.016 14.7 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 KXG53659.1 - 0.019 14.2 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KXG53659.1 - 0.024 14.8 1.4 0.1 12.8 0.0 2.8 3 1 0 3 3 3 0 AAA domain ResIII PF04851.15 KXG53659.1 - 0.025 14.6 0.0 8.5 6.3 0.0 2.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KXG53659.1 - 0.028 14.8 0.0 0.08 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KXG53659.1 - 0.051 14.1 0.0 0.17 12.4 0.0 1.9 2 0 0 2 2 1 0 ABC transporter AAA_24 PF13479.6 KXG53659.1 - 0.051 13.3 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KXG53659.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 KXG53659.1 - 0.068 12.6 0.0 0.22 10.9 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein cobW PF02492.19 KXG53659.1 - 0.079 12.5 0.6 0.45 10.1 0.0 2.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KXG53659.1 - 0.11 12.5 0.1 0.78 9.6 0.1 2.2 2 0 0 2 2 2 0 NACHT domain DAD PF02109.16 KXG53660.1 - 2.8e-46 156.3 0.5 5e-46 155.5 0.5 1.4 1 1 0 1 1 1 1 DAD family Fungal_trans PF04082.18 KXG53661.1 - 7.4e-17 61.2 1.4 2.9e-16 59.3 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG53661.1 - 6.6e-10 39.0 11.1 6.6e-10 39.0 11.1 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LicD PF04991.13 KXG53662.1 - 1e-23 84.7 10.8 1.7e-17 64.3 3.1 2.4 2 1 1 3 3 3 2 LicD family Fungal_trans PF04082.18 KXG53663.1 - 0.00023 20.3 0.1 0.00043 19.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG53663.1 - 0.0022 18.1 11.3 0.0034 17.5 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SGT1 PF07093.11 KXG53663.1 - 0.055 11.9 2.0 0.086 11.3 2.0 1.2 1 0 0 1 1 1 0 SGT1 protein DUF726 PF05277.12 KXG53665.1 - 2.2e-127 424.7 3.7 3.3e-127 424.1 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Polysacc_deac_1 PF01522.21 KXG53665.1 - 0.076 12.9 0.2 0.17 11.7 0.2 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase RTC4 PF14474.6 KXG53666.1 - 5.1e-31 107.4 0.0 9.3e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain TFR_dimer PF04253.15 KXG53667.1 - 2.2e-31 108.5 0.0 3.6e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KXG53667.1 - 2.7e-20 72.9 0.0 4.5e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXG53667.1 - 2.4e-08 33.9 0.1 7.7e-08 32.3 0.1 1.8 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 KXG53667.1 - 0.004 16.7 0.0 0.0081 15.7 0.0 1.4 1 0 0 1 1 1 1 Nicastrin Tmemb_14 PF03647.13 KXG53668.1 - 1.9e-18 67.0 9.8 2.4e-18 66.6 9.8 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C zf-C2H2_4 PF13894.6 KXG53669.1 - 4.5e-06 27.1 2.3 0.055 14.3 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXG53669.1 - 0.00047 20.4 3.4 0.017 15.5 0.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KXG53669.1 - 0.16 12.3 0.8 8.3 6.8 0.2 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_12 PF18658.1 KXG53670.1 - 0.034 13.7 0.0 0.092 12.3 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger C2H2-type DBINO PF13892.6 KXG53670.1 - 2.2 8.7 5.7 0.46 10.8 1.6 2.0 2 0 0 2 2 2 0 DNA-binding domain tRNA-synt_1c PF00749.21 KXG53671.1 - 1.6e-94 316.4 0.3 7.4e-78 261.6 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KXG53671.1 - 3.6e-36 124.7 0.0 7.6e-36 123.6 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KXG53671.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Bromo_TP_like PF17027.5 KXG53671.1 - 0.0097 16.1 0.1 0.027 14.6 0.1 1.7 1 0 0 1 1 1 1 Histone-fold protein ComC PF03047.14 KXG53671.1 - 0.052 13.3 0.0 2.6 7.9 0.0 2.8 2 0 0 2 2 2 0 COMC family GluRS_N PF18466.1 KXG53671.1 - 0.091 13.2 0.4 0.63 10.5 0.0 2.5 2 0 0 2 2 2 0 Glutamate--tRNA ligase N-terminal domain CMD PF02627.20 KXG53672.1 - 2.4e-07 30.7 0.1 4.5e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family CARD_2 PF16739.5 KXG53672.1 - 0.16 12.0 0.0 1.1 9.3 0.0 2.1 1 1 0 1 1 1 0 Caspase recruitment domain DUF5427 PF10310.9 KXG53673.1 - 2.4e-163 544.4 0.2 2.8e-163 544.2 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 KXG53673.1 - 0.019 15.1 1.2 0.068 13.4 0.2 2.2 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain SARAF PF06682.12 KXG53673.1 - 0.4 10.3 4.7 0.61 9.7 4.7 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SurE PF01975.17 KXG53674.1 - 6.5e-53 179.4 0.0 8.7e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Zn_clus PF00172.18 KXG53675.1 - 0.0039 17.3 9.9 0.0084 16.2 9.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_helicase PF00910.22 KXG53675.1 - 0.062 13.7 0.2 1.1 9.7 0.0 2.7 3 0 0 3 3 3 0 RNA helicase BAALC_N PF06989.12 KXG53675.1 - 2.5 8.5 4.5 5.6 7.4 0.1 3.3 3 0 0 3 3 3 0 BAALC N-terminus DUF2462 PF09495.10 KXG53676.1 - 5.4e-20 71.9 4.2 5.4e-20 71.9 4.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) NGP1NT PF08153.12 KXG53678.1 - 2e-49 167.0 0.3 3.1e-49 166.4 0.3 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KXG53678.1 - 1.3e-16 60.7 0.0 5.2e-13 49.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KXG53678.1 - 3.2e-05 23.5 0.0 0.00024 20.6 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXG53678.1 - 0.00081 19.5 0.0 1.8 8.6 0.0 3.5 2 1 1 3 3 3 1 Dynamin family Arf PF00025.21 KXG53678.1 - 0.00085 18.8 0.1 0.25 10.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXG53678.1 - 0.0015 18.5 0.0 0.0041 17.0 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase Roc PF08477.13 KXG53678.1 - 0.058 13.6 0.1 15 5.8 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KXG53678.1 - 0.11 12.0 0.0 6.7 6.2 0.0 2.9 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain NACHT PF05729.12 KXG53679.1 - 4e-09 36.6 0.5 1.7e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 KXG53679.1 - 6.6e-06 25.5 0.1 2.5e-05 23.6 0.1 2.0 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KXG53679.1 - 3.6e-05 24.2 0.4 0.00019 21.9 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXG53679.1 - 6.9e-05 23.1 0.5 0.00049 20.4 0.0 2.5 2 1 1 3 3 2 1 AAA domain Ank_4 PF13637.6 KXG53679.1 - 7e-05 23.3 0.0 0.094 13.3 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXG53679.1 - 0.0001 22.8 0.0 0.00035 21.1 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) AAA PF00004.29 KXG53679.1 - 0.00067 20.1 0.6 0.0059 17.0 0.6 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Helo_like_N PF17111.5 KXG53679.1 - 0.0012 18.3 3.5 0.0043 16.5 3.6 2.0 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins ATPase_2 PF01637.18 KXG53679.1 - 0.0021 18.0 0.1 0.0049 16.8 0.1 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KXG53679.1 - 0.0023 18.1 0.2 0.0067 16.6 0.2 1.9 1 1 0 1 1 1 1 AAA domain Ank_5 PF13857.6 KXG53679.1 - 0.0044 17.3 0.0 0.2 12.0 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG53679.1 - 0.0048 17.3 0.0 0.88 10.3 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat AAA_14 PF13173.6 KXG53679.1 - 0.0075 16.3 0.0 0.086 12.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXG53679.1 - 0.013 15.2 0.0 0.044 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXG53679.1 - 0.014 15.9 0.1 0.16 12.5 0.0 2.6 3 0 0 3 3 2 0 ABC transporter SRP54 PF00448.22 KXG53679.1 - 0.02 14.6 1.1 0.068 12.8 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ploopntkinase3 PF18751.1 KXG53679.1 - 0.026 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 PIF1 PF05970.14 KXG53679.1 - 0.028 13.6 0.0 0.062 12.5 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase SRPRB PF09439.10 KXG53679.1 - 0.03 13.8 0.3 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KXG53679.1 - 0.031 14.2 0.4 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 KXG53679.1 - 0.031 13.5 0.4 0.22 10.8 0.0 2.6 3 1 1 4 4 3 0 Zeta toxin AAA_29 PF13555.6 KXG53679.1 - 0.048 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KXG53679.1 - 0.057 13.8 0.0 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 KXG53679.1 - 0.067 13.2 0.0 0.23 11.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KXG53679.1 - 0.081 12.6 0.2 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KXG53679.1 - 0.091 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 KXG53679.1 - 0.094 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KXG53679.1 - 0.12 12.1 0.1 0.42 10.3 0.1 1.9 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ank PF00023.30 KXG53679.1 - 0.13 12.8 0.0 40 4.9 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat AAA_23 PF13476.6 KXG53679.1 - 0.22 12.0 3.1 0.62 10.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXG53679.1 - 0.39 11.3 1.7 1.7 9.2 0.2 2.5 1 1 1 2 2 2 0 AAA domain Pkinase PF00069.25 KXG53680.1 - 1.3e-42 146.0 0.0 4.9e-42 144.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG53680.1 - 2.2e-28 99.2 0.0 3.4e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXG53680.1 - 0.0001 21.2 0.0 0.00018 20.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXG53680.1 - 0.0008 18.8 0.0 0.0022 17.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXG53680.1 - 0.0027 17.7 0.7 0.06 13.3 0.1 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXG53680.1 - 0.0048 16.3 0.0 0.013 14.8 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans PF04082.18 KXG53681.1 - 1.4e-14 53.8 0.0 2.4e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KXG53682.1 - 4.8e-19 68.6 0.0 1.4e-17 63.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG53682.1 - 2.9e-07 30.3 0.0 6.9e-07 29.1 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG53682.1 - 1.8e-06 28.0 0.1 3.1e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Prefoldin_3 PF13758.6 KXG53683.1 - 9.6e-35 118.6 0.5 2.3e-34 117.4 0.5 1.7 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 KXG53683.1 - 2.4e-14 53.9 19.1 5.2e-14 52.9 2.3 4.6 4 1 1 5 5 5 2 Domain of unknown function (DUF3835) Prefoldin_2 PF01920.20 KXG53683.1 - 0.56 10.2 3.6 7.8 6.5 1.8 3.2 1 1 1 2 2 2 0 Prefoldin subunit MAT1 PF06391.13 KXG53684.1 - 5.3e-42 144.0 15.3 7.6e-42 143.5 15.3 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KXG53684.1 - 2.3e-32 110.6 8.6 3.6e-32 110.0 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXG53684.1 - 5.7e-05 22.9 5.5 0.00011 22.0 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXG53684.1 - 0.0003 20.6 3.6 0.00063 19.5 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXG53684.1 - 0.00036 20.3 4.9 0.0013 18.6 5.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXG53684.1 - 0.0015 18.9 6.1 0.0026 18.1 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KXG53684.1 - 0.0038 17.0 6.2 0.036 13.9 1.9 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KXG53684.1 - 0.0053 16.4 1.4 0.011 15.3 1.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KXG53684.1 - 0.011 15.7 7.7 0.11 12.4 8.2 2.1 1 1 1 2 2 2 0 zinc-RING finger domain Cas_GSU0054 PF09609.10 KXG53684.1 - 0.041 12.6 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) DUF3797 PF12677.7 KXG53684.1 - 0.055 13.4 2.4 0.15 12.0 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-RING_UBOX PF13445.6 KXG53684.1 - 0.21 11.6 6.0 0.43 10.6 6.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Nup88 PF10168.9 KXG53684.1 - 0.61 7.8 6.6 0.83 7.4 6.6 1.1 1 0 0 1 1 1 0 Nuclear pore component Prok-RING_4 PF14447.6 KXG53684.1 - 0.67 9.9 7.9 16 5.4 8.7 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Cep57_MT_bd PF06657.13 KXG53685.1 - 8.4e-30 103.0 0.1 8.4e-30 103.0 0.1 4.9 3 1 2 5 5 5 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 KXG53685.1 - 2.2e-20 72.5 10.4 2.2e-20 72.5 10.4 4.5 5 0 0 5 5 5 1 Centrosome localisation domain of PPC89 DivIC PF04977.15 KXG53685.1 - 0.0041 16.8 4.2 0.0041 16.8 4.2 4.8 5 1 1 6 6 6 1 Septum formation initiator HALZ PF02183.18 KXG53685.1 - 0.013 15.7 1.5 0.013 15.7 1.5 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper T4-gp15_tss PF16724.5 KXG53685.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 T4-like virus Myoviridae tail sheath stabiliser FlaC_arch PF05377.11 KXG53685.1 - 3.3 8.2 14.0 15 6.1 0.1 5.6 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) Spore_III_AB PF09548.10 KXG53685.1 - 4.1 7.5 7.2 0.88 9.7 0.1 3.3 4 0 0 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) TssO PF17561.2 KXG53685.1 - 4.9 7.2 12.8 0.34 11.0 4.4 3.0 3 0 0 3 3 3 0 Type VI secretion system, TssO Shugoshin_N PF07558.11 KXG53685.1 - 7.3 6.5 12.1 0.26 11.2 2.9 3.2 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region His_Phos_2 PF00328.22 KXG53686.1 - 6.5e-71 239.7 0.0 7.8e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CTP_transf_like PF01467.26 KXG53688.1 - 8.6e-05 22.8 0.1 0.00036 20.8 0.1 1.9 1 1 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KXG53688.1 - 0.13 12.2 0.5 0.25 11.2 0.1 1.7 2 0 0 2 2 2 0 FAD synthetase WD40 PF00400.32 KXG53689.1 - 3.1e-13 50.0 7.5 5.8e-05 23.8 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Acyl_transf_3 PF01757.22 KXG53690.1 - 6.8e-34 117.4 35.5 1.1e-33 116.7 35.5 1.4 1 0 0 1 1 1 1 Acyltransferase family UPF0182 PF03699.13 KXG53690.1 - 0.033 12.3 1.3 0.046 11.8 1.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF4395 PF14340.6 KXG53690.1 - 0.37 11.1 0.0 0.37 11.1 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4395) mRNA_triPase PF02940.15 KXG53692.1 - 4.3e-61 206.4 0.4 6.4e-61 205.9 0.4 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Fungal_trans_2 PF11951.8 KXG53693.1 - 2.1e-12 46.6 1.9 2.3e-07 30.0 0.4 2.2 1 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG53693.1 - 2e-10 40.6 9.0 3.7e-10 39.7 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXG53694.1 - 7.8e-28 97.4 15.2 7.8e-28 97.4 15.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.24 KXG53695.1 - 9.5e-34 117.5 2.0 1.1e-33 117.3 2.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG53695.1 - 0.012 15.8 0.1 0.032 14.5 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXG53695.1 - 0.031 14.3 0.2 0.31 11.0 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXG53695.1 - 0.031 13.4 0.0 0.061 12.5 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF4623 PF15416.6 KXG53695.1 - 0.073 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) Pyr_redox_2 PF07992.14 KXG53695.1 - 0.079 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RhoGAP-FF1 PF16512.5 KXG53695.1 - 0.16 12.7 0.0 0.34 11.6 0.0 1.4 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain Amidase PF01425.21 KXG53696.1 - 4.6e-97 325.8 0.0 6.2e-97 325.4 0.0 1.2 1 0 0 1 1 1 1 Amidase CTD PF12815.7 KXG53697.1 - 2e-20 73.1 34.0 3.6e-18 65.9 19.7 4.0 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.8 KXG53697.1 - 6.4e-18 65.6 10.5 6.4e-18 65.6 10.5 3.8 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 KXG53697.1 - 2.5e-16 59.3 0.0 4.4e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KXG53697.1 - 6.6e-11 41.8 12.1 0.0037 17.2 0.4 4.2 4 0 0 4 4 4 3 KOW motif DUF3912 PF13051.6 KXG53697.1 - 0.0054 17.0 0.4 2.5 8.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3912) Ank_2 PF12796.7 KXG53698.1 - 2.9e-05 24.6 0.0 0.17 12.5 0.0 3.3 2 2 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG53698.1 - 0.019 15.5 0.2 4.4 8.2 0.0 3.9 5 0 0 5 5 5 0 Ankyrin repeat MiaE_2 PF13794.6 KXG53698.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Acyl-CoA_dh_1 PF00441.24 KXG53699.1 - 1.1e-42 145.7 0.2 1.6e-42 145.2 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXG53699.1 - 7.2e-22 77.4 0.1 1.2e-21 76.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXG53699.1 - 2.5e-20 73.2 0.0 5.8e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 KXG53699.1 - 2.8e-19 69.0 0.2 5.4e-19 68.1 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 KXG53699.1 - 1.5e-09 38.2 0.0 2.3e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RPN2_C PF18004.1 KXG53700.1 - 3.1e-56 189.7 9.5 3.1e-56 189.7 9.5 3.0 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KXG53700.1 - 1.6e-35 119.8 20.6 7.9e-10 38.7 0.1 8.5 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KXG53700.1 - 1e-21 77.1 0.0 1.8e-14 53.9 0.0 4.8 3 1 0 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 KXG53700.1 - 2.6e-06 27.8 0.1 0.001 19.5 0.0 5.0 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.22 KXG53700.1 - 4.8e-05 23.3 0.0 12 6.4 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat HEAT_PBS PF03130.16 KXG53700.1 - 0.03 15.0 2.1 1.1 10.2 0.0 4.1 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Cnd1 PF12717.7 KXG53700.1 - 0.034 14.2 4.3 0.26 11.3 0.0 3.3 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Seryl_tRNA_N PF02403.22 KXG53701.1 - 0.0045 17.2 2.7 0.015 15.5 2.4 2.0 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Fez1 PF06818.15 KXG53701.1 - 0.0096 16.4 8.0 0.024 15.1 8.0 1.6 1 1 0 1 1 1 1 Fez1 Paralemmin PF03285.15 KXG53701.1 - 0.019 14.6 1.0 0.047 13.3 1.0 1.6 1 0 0 1 1 1 0 Paralemmin DUF1664 PF07889.12 KXG53701.1 - 0.045 13.8 2.8 0.073 13.1 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nmad5 PF18757.1 KXG53701.1 - 0.062 13.5 0.3 0.15 12.2 0.3 1.7 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 AKNA PF12443.8 KXG53701.1 - 0.067 13.8 0.5 0.24 12.1 0.5 1.9 1 0 0 1 1 1 0 AT-hook-containing transcription factor SLX9 PF15341.6 KXG53701.1 - 0.088 13.2 1.4 0.17 12.3 1.4 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 CLZ PF16526.5 KXG53701.1 - 0.093 13.1 4.8 0.11 12.8 0.9 3.0 3 0 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Phage_GP20 PF06810.11 KXG53701.1 - 0.11 12.3 2.5 0.3 10.9 2.3 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 Noelin-1 PF12308.8 KXG53701.1 - 0.11 12.4 0.5 0.41 10.7 0.5 1.9 1 0 0 1 1 1 0 Neurogenesis glycoprotein DUF2730 PF10805.8 KXG53701.1 - 0.12 12.5 0.5 0.36 10.9 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) RPW8 PF05659.11 KXG53701.1 - 0.12 12.0 0.4 0.95 9.2 0.1 2.4 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 COG5 PF10392.9 KXG53701.1 - 0.16 12.2 5.9 0.16 12.1 3.0 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 LemA PF04011.12 KXG53701.1 - 0.5 10.2 3.2 16 5.3 2.9 2.6 2 1 0 2 2 2 0 LemA family YabA PF06156.13 KXG53701.1 - 0.69 10.6 3.0 1.2 9.8 1.8 2.0 2 0 0 2 2 1 0 Initiation control protein YabA Fib_alpha PF08702.10 KXG53701.1 - 0.71 10.0 6.6 0.18 12.0 1.3 2.5 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family LMBR1 PF04791.16 KXG53701.1 - 0.85 8.4 2.0 1 8.2 2.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Baculo_PEP_C PF04513.12 KXG53701.1 - 0.89 9.6 4.0 0.58 10.2 1.7 1.9 2 1 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 KXG53701.1 - 0.91 10.0 2.7 1.2 9.6 0.4 2.4 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) CorA PF01544.18 KXG53701.1 - 0.96 8.7 5.7 2.8 7.2 2.0 2.6 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein CENP-H PF05837.12 KXG53701.1 - 1.3 9.5 9.2 0.66 10.4 4.8 2.7 2 1 1 3 3 3 0 Centromere protein H (CENP-H) TMCO5 PF14992.6 KXG53701.1 - 1.5 8.3 11.5 0.65 9.5 8.5 1.8 1 1 0 2 2 2 0 TMCO5 family ABC_tran_CTD PF16326.5 KXG53701.1 - 1.7 9.0 7.3 2.1 8.6 3.8 2.7 3 0 0 3 3 2 0 ABC transporter C-terminal domain Syntaxin-6_N PF09177.11 KXG53701.1 - 3.9 8.1 7.3 14 6.3 4.4 3.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal TMPIT PF07851.13 KXG53701.1 - 4.2 6.5 4.7 23 4.1 1.6 2.6 1 1 1 3 3 3 0 TMPIT-like protein DUF724 PF05266.14 KXG53701.1 - 5.3 6.8 9.1 3.8 7.3 5.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Abhydrolase_6 PF12697.7 KXG53702.1 - 2e-05 25.3 0.5 2.9e-05 24.8 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG53702.1 - 0.014 15.0 0.1 0.056 13.1 0.1 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG53702.1 - 0.035 13.4 0.1 12 5.0 0.0 2.9 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Cutinase PF01083.22 KXG53702.1 - 0.045 13.7 0.0 0.099 12.6 0.0 1.5 2 0 0 2 2 2 0 Cutinase DUF3336 PF11815.8 KXG53703.1 - 1.4e-35 122.0 1.1 2.6e-35 121.1 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KXG53703.1 - 1.5e-21 77.5 0.0 2.8e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase TOM6p PF15184.6 KXG53703.1 - 0.018 14.8 0.0 0.068 13.0 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit TOM6 homolog CARMIL_C PF16000.5 KXG53704.1 - 1 8.9 3.3 2.8 7.5 3.2 1.8 1 1 0 1 1 1 0 CARMIL C-terminus DLIC PF05783.11 KXG53704.1 - 6.9 5.4 4.6 11 4.7 4.6 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Sigma70_r4_2 PF08281.12 KXG53705.1 - 0.00013 21.6 0.1 0.00025 20.6 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 PMI_typeI PF01238.21 KXG53709.1 - 1.2e-56 192.5 1.5 2.3e-53 181.7 1.5 3.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KXG53709.1 - 0.0023 17.6 0.0 0.33 10.7 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KXG53709.1 - 0.078 12.9 0.1 40 4.1 0.0 3.1 2 1 1 3 3 3 0 AraC-like ligand binding domain TMEM154 PF15102.6 KXG53711.1 - 0.038 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 TMEM154 protein family RCR PF12273.8 KXG53711.1 - 0.54 10.9 19.4 2.7 8.7 19.4 2.1 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 KXG53711.1 - 2.1 9.3 6.9 18 6.3 6.9 2.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Med8 PF10232.9 KXG53712.1 - 4.6e-63 212.9 0.4 5.1e-63 212.8 0.4 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Myc_N PF01056.18 KXG53712.1 - 0.13 12.1 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PQ-loop PF04193.14 KXG53713.1 - 9.5e-21 73.3 11.3 9.6e-11 41.3 1.2 2.9 3 0 0 3 3 3 2 PQ loop repeat DoxX_3 PF13781.6 KXG53713.1 - 0.021 15.5 1.1 0.021 15.5 1.1 1.9 2 0 0 2 2 2 0 DoxX-like family UbiA PF01040.18 KXG53714.1 - 9.9e-55 185.6 20.1 9.9e-55 185.6 20.1 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family Cutinase PF01083.22 KXG53715.1 - 5.3e-43 147.0 0.2 6.7e-43 146.7 0.2 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.16 KXG53715.1 - 0.0076 16.1 0.0 0.02 14.7 0.0 1.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase PE-PPE PF08237.11 KXG53715.1 - 0.033 13.7 0.1 0.054 13.0 0.1 1.4 1 0 0 1 1 1 0 PE-PPE domain Hydrolase_4 PF12146.8 KXG53715.1 - 0.091 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 tRNA-synt_2 PF00152.20 KXG53716.1 - 2.9e-89 299.2 0.0 4e-89 298.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXG53716.1 - 0.0061 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.25 KXG53716.1 - 0.015 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) FliN_N PF16973.5 KXG53716.1 - 0.095 12.5 0.2 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 Flagellar motor switch protein FliN N-terminal ABC_tran PF00005.27 KXG53717.1 - 4.1e-46 156.9 0.0 3.3e-29 102.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXG53717.1 - 6.5e-40 137.5 28.5 3.5e-26 92.5 10.2 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KXG53717.1 - 2.6e-10 40.1 0.0 0.0051 16.3 0.0 4.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXG53717.1 - 0.00039 20.7 0.4 1.6 9.0 0.0 3.3 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KXG53717.1 - 0.0005 20.1 0.0 0.089 12.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXG53717.1 - 0.00056 20.3 2.9 0.041 14.3 0.2 3.0 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 KXG53717.1 - 0.0013 17.9 0.0 0.071 12.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 KXG53717.1 - 0.0013 18.4 0.8 0.4 10.4 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 KXG53717.1 - 0.003 17.7 0.8 0.88 9.6 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 KXG53717.1 - 0.0037 17.8 0.3 0.67 10.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 KXG53717.1 - 0.009 15.9 0.3 4.9 7.0 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF2075 PF09848.9 KXG53717.1 - 0.02 14.2 0.1 0.27 10.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 KXG53717.1 - 0.034 13.1 0.0 0.086 11.8 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_21 PF13304.6 KXG53717.1 - 0.086 12.6 0.1 9.7 5.9 0.0 3.5 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 KXG53717.1 - 0.11 12.3 0.6 2.6 7.7 0.0 3.4 5 0 0 5 5 5 0 IstB-like ATP binding protein Connexin PF00029.19 KXG53717.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Connexin AAA_10 PF12846.7 KXG53717.1 - 0.16 10.8 0.1 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.6 KXG53717.1 - 0.2 11.2 4.0 8.7 5.9 0.2 3.5 2 1 1 3 3 3 0 AAA domain LigD_N PF13298.6 KXG53718.1 - 1e-19 70.8 0.0 1.7e-13 50.7 0.0 2.5 1 1 1 2 2 2 2 DNA polymerase Ligase (LigD) RhoGAP PF00620.27 KXG53718.1 - 0.088 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 RhoGAP domain FAD_binding_4 PF01565.23 KXG53719.1 - 1.4e-26 92.9 1.7 1.4e-26 92.9 1.7 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXG53719.1 - 7.4e-11 42.0 0.0 1.6e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Sulf_transp PF04143.14 KXG53720.1 - 4.7e-06 26.4 1.7 4.7e-06 26.4 1.7 3.2 3 0 0 3 3 3 2 Sulphur transport CopD PF05425.13 KXG53720.1 - 0.033 14.6 0.1 0.033 14.6 0.1 2.2 2 1 0 2 2 2 0 Copper resistance protein D Peptidase_M28 PF04389.17 KXG53721.1 - 5e-31 107.9 0.0 6.5e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 HTH_10 PF04967.12 KXG53723.1 - 0.055 13.3 0.1 0.15 11.9 0.1 1.8 1 0 0 1 1 1 0 HTH DNA binding domain PPL5 PF18168.1 KXG53723.1 - 0.13 11.5 0.1 0.13 11.5 0.1 2.1 1 1 0 2 2 2 0 Prim-pol family 5 YmgD PF16456.5 KXG53723.1 - 0.26 11.4 2.6 0.6 10.2 2.6 1.6 1 0 0 1 1 1 0 YmgD protein CDC27 PF09507.10 KXG53723.1 - 0.32 10.3 26.1 0.42 9.9 26.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MCLC PF05934.11 KXG53723.1 - 1.3 7.7 10.0 1.5 7.4 10.0 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) GAGA_bind PF06217.12 KXG53723.1 - 7 6.8 14.0 0.82 9.9 8.7 1.8 1 1 1 2 2 2 0 GAGA binding protein-like family Red1 PF07964.11 KXG53723.1 - 7.9 4.6 18.2 10 4.2 18.2 1.1 1 0 0 1 1 1 0 Rec10 / Red1 RGS-like PF09128.11 KXG53724.1 - 0.035 13.8 0.5 0.054 13.2 0.5 1.3 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain MscS_TM PF12794.7 KXG53724.1 - 3.7 6.3 4.8 4.4 6.1 4.8 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 RR_TM4-6 PF06459.12 KXG53725.1 - 0.045 13.6 7.7 0.052 13.4 7.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KXG53725.1 - 6 5.5 4.7 6.9 5.3 4.7 1.1 1 0 0 1 1 1 0 Presenilin DUF1307 PF06998.11 KXG53726.1 - 0.0069 16.4 0.9 0.019 15.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1307) Gly-rich_Ago1 PF12764.7 KXG53726.1 - 0.089 13.6 1.0 0.29 11.9 0.8 2.1 1 1 0 1 1 1 0 Glycine-rich region of argonaut MutS_V PF00488.21 KXG53727.1 - 1.4e-67 227.4 0.1 2.3e-67 226.7 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXG53727.1 - 1.2e-40 139.8 0.0 2.4e-40 138.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KXG53727.1 - 8.4e-33 113.0 0.1 2e-32 111.8 0.0 1.7 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KXG53727.1 - 1.6e-15 57.6 0.0 4e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KXG53727.1 - 2.7e-13 50.1 0.3 5.4e-13 49.1 0.3 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_27 PF13514.6 KXG53727.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXG53727.1 - 0.15 11.3 0.7 0.46 9.7 0.0 2.0 3 0 0 3 3 3 0 Zeta toxin PGA2 PF07543.12 KXG53727.1 - 3.1 7.8 9.0 11 6.0 9.0 2.0 1 0 0 1 1 1 0 Protein trafficking PGA2 Shugoshin_C PF07557.11 KXG53727.1 - 7.6 6.4 6.6 0.58 10.0 1.2 2.0 2 0 0 2 2 2 0 Shugoshin C terminus tRNA-synt_1b PF00579.25 KXG53728.1 - 7.1e-71 238.9 0.0 9.3e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KXG53728.1 - 3.7e-46 155.8 0.0 8.1e-46 154.7 0.0 1.6 2 0 0 2 2 2 1 Tyrosyl-tRNA synthetase C-terminal domain Raffinose_syn PF05691.12 KXG53729.1 - 4.3e-50 170.3 3.3 1.3e-48 165.5 1.0 2.8 2 1 0 2 2 2 1 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.18 KXG53729.1 - 0.0021 17.1 0.1 0.0038 16.2 0.1 1.3 1 0 0 1 1 1 1 Melibiase ADH_zinc_N PF00107.26 KXG53731.1 - 2.6e-24 85.7 0.4 4e-24 85.1 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG53731.1 - 3e-15 57.5 0.0 8.4e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG53731.1 - 4.5e-12 45.8 0.0 2.8e-11 43.2 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KXG53731.1 - 0.0018 18.5 0.0 0.0035 17.6 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain NMO PF03060.15 KXG53731.1 - 0.034 13.5 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase AlaDh_PNT_C PF01262.21 KXG53731.1 - 0.057 12.7 0.1 0.089 12.1 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Acetyltransf_1 PF00583.25 KXG53732.1 - 4.5e-14 52.7 0.0 6.4e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXG53732.1 - 3.1e-07 30.4 0.0 5.3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXG53732.1 - 6.4e-07 29.7 0.1 1e-06 29.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG53732.1 - 3.4e-05 23.7 0.0 5.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXG53732.1 - 0.023 14.8 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PIG-U PF06728.13 KXG53733.1 - 1.2e-120 403.1 25.7 1.4e-120 402.9 25.7 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.13 KXG53733.1 - 8.2e-05 22.6 0.1 0.00016 21.7 0.1 1.5 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) 8TM_micro PF17028.5 KXG53733.1 - 0.58 9.8 8.9 2.4 7.8 8.9 1.9 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain Pescadillo_N PF06732.11 KXG53734.1 - 3.1e-124 414.0 0.0 3.1e-124 414.0 0.0 1.6 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KXG53734.1 - 0.00014 22.2 0.0 0.00097 19.5 0.0 2.4 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Astro_capsid_p PF12226.8 KXG53734.1 - 0.004 16.4 10.3 0.004 16.4 10.3 2.0 2 0 0 2 2 2 1 Turkey astrovirus capsid protein BRCT PF00533.26 KXG53734.1 - 0.092 13.1 0.0 0.83 10.1 0.0 2.6 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DUF3405 PF11885.8 KXG53735.1 - 5.5e-140 467.4 6.5 7.6e-140 466.9 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) NAD_binding_2 PF03446.15 KXG53735.1 - 5.8e-27 94.8 0.1 1.3e-26 93.7 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXG53735.1 - 9.9e-07 29.0 0.0 1.9e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KXG53735.1 - 0.00018 22.0 0.1 0.0012 19.4 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KXG53735.1 - 0.032 14.3 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KXG53735.1 - 0.042 13.2 0.0 0.097 12.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PD40 PF07676.12 KXG53736.1 - 5.8e-42 140.8 24.2 1.5e-08 34.3 0.6 9.7 9 0 0 9 9 9 8 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 KXG53736.1 - 1.1e-11 44.1 4.1 0.0028 16.5 0.3 5.9 7 1 0 7 7 7 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3748 PF12566.8 KXG53736.1 - 0.00084 19.3 1.2 2.1 8.3 0.0 4.5 5 0 0 5 5 5 1 Protein of unknown function (DUF3748) WD40 PF00400.32 KXG53736.1 - 0.0083 17.0 8.1 3.5 8.7 0.1 5.7 6 1 1 7 7 7 1 WD domain, G-beta repeat GspH PF12019.8 KXG53736.1 - 6.5 7.2 17.6 2.2 8.7 0.2 4.8 2 2 2 4 4 4 0 Type II transport protein GspH RRN9 PF10680.9 KXG53737.1 - 2.7e-14 53.2 0.8 2.7e-14 53.2 0.8 3.1 3 0 0 3 3 3 1 RNA polymerase I specific transcription initiation factor GP24_25 PF17388.2 KXG53737.1 - 0.094 12.7 4.0 0.12 12.4 2.8 1.8 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 zf-C2H2_aberr PF17017.5 KXG53737.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Aberrant zinc-finger zf-C2H2 PF00096.26 KXG53737.1 - 3.4 8.3 4.7 0.77 10.3 1.3 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Aldedh PF00171.22 KXG53739.1 - 9.9e-169 561.7 0.5 1.1e-168 561.5 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Mo-co_dimer PF03404.16 KXG53739.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Pkinase PF00069.25 KXG53740.1 - 5e-69 232.6 0.1 1.1e-68 231.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG53740.1 - 2.2e-35 122.2 0.0 3.3e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXG53740.1 - 3.7e-07 29.7 0.1 3.7e-07 29.7 0.1 2.0 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_1 PF00170.21 KXG53740.1 - 1.3e-06 28.4 9.6 3.2e-06 27.1 9.6 1.7 1 0 0 1 1 1 1 bZIP transcription factor Haspin_kinase PF12330.8 KXG53740.1 - 8.2e-06 25.0 0.1 1.5e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain bZIP_2 PF07716.15 KXG53740.1 - 1e-05 25.5 9.4 2e-05 24.6 9.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Kinase-like PF14531.6 KXG53740.1 - 8.9e-05 21.9 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KXG53740.1 - 0.0029 17.3 0.0 0.0056 16.3 0.0 1.6 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KXG53740.1 - 0.0085 16.0 0.4 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXG53740.1 - 0.012 15.2 0.1 0.012 15.2 0.1 1.7 2 0 0 2 2 2 0 RIO1 family bZIP_Maf PF03131.17 KXG53740.1 - 0.053 14.0 5.1 0.12 13.0 5.1 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor MARVEL PF01284.23 KXG53741.1 - 1.4e-12 47.8 9.6 1.9e-12 47.4 9.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain HIG_1_N PF04588.13 KXG53742.1 - 1.1e-27 95.9 0.2 1.6e-27 95.5 0.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region SPT16 PF08644.11 KXG53742.1 - 0.11 12.7 0.6 0.16 12.1 0.6 1.2 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF4131 PF13567.6 KXG53742.1 - 0.17 11.5 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) ATP-synt_E PF05680.12 KXG53742.1 - 0.74 10.2 5.8 0.28 11.5 2.6 1.9 1 1 1 2 2 2 0 ATP synthase E chain PALP PF00291.25 KXG53743.1 - 7.6e-76 255.3 0.1 1e-75 254.9 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KXG53743.1 - 1.4e-45 153.0 0.0 4.5e-22 77.6 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase GTP_EFTU PF00009.27 KXG53744.1 - 1e-57 194.8 0.4 1.7e-57 194.1 0.4 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KXG53744.1 - 7.9e-33 112.4 0.0 1.8e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KXG53744.1 - 2.2e-32 111.4 0.1 4.5e-32 110.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KXG53744.1 - 4.3e-23 81.2 0.0 1e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXG53744.1 - 6e-12 45.8 0.1 1.4e-11 44.6 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KXG53744.1 - 7e-06 25.9 0.0 2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain DUF442 PF04273.13 KXG53744.1 - 0.13 12.4 0.0 1.6 8.8 0.0 2.6 3 0 0 3 3 3 0 Putative phosphatase (DUF442) Mitofilin PF09731.9 KXG53747.1 - 5.4e-155 517.7 32.0 2.1e-125 420.0 28.3 2.2 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Ras PF00071.22 KXG53747.1 - 2.3e-50 170.3 0.5 2.3e-50 170.3 0.5 1.8 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KXG53747.1 - 1.1e-27 96.6 1.3 2.2e-27 95.6 0.4 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG53747.1 - 3.7e-10 39.5 0.1 8.3e-10 38.4 0.1 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXG53747.1 - 6.9e-06 25.7 0.1 1.7e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXG53747.1 - 0.0022 17.4 0.1 0.0046 16.3 0.1 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Sld5 PF05916.11 KXG53747.1 - 2.8 8.4 5.9 8.4 6.9 1.9 2.6 1 1 1 2 2 2 0 GINS complex protein Syja_N PF02383.18 KXG53748.1 - 1.3e-90 303.9 0.0 1.7e-90 303.6 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Presenilin PF01080.17 KXG53748.1 - 0.048 12.4 3.7 0.085 11.6 3.7 1.3 1 0 0 1 1 1 0 Presenilin VirB3 PF05101.13 KXG53748.1 - 0.84 9.9 6.2 2.4 8.5 6.2 1.7 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Mur_ligase_M PF08245.12 KXG53749.1 - 2.5e-07 30.9 0.3 4.5e-05 23.5 0.1 3.3 2 1 0 2 2 2 1 Mur ligase middle domain DUF2188 PF09954.9 KXG53749.1 - 0.086 13.0 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) NMT_C PF02799.15 KXG53750.1 - 2.9e-92 307.9 0.1 5.5e-92 307.0 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KXG53750.1 - 7.3e-76 253.4 0.1 1.5e-73 246.0 0.0 2.2 2 0 0 2 2 2 2 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KXG53750.1 - 6.9e-06 26.2 0.1 0.00042 20.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG53750.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF3024 PF11225.8 KXG53750.1 - 0.087 13.1 1.2 6 7.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) Acetyltransf_3 PF13302.7 KXG53750.1 - 0.11 13.2 0.0 0.24 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RTA1 PF04479.13 KXG53751.1 - 1.3e-52 178.5 5.1 1.8e-52 178.0 5.1 1.2 1 0 0 1 1 1 1 RTA1 like protein CPBP PF02517.16 KXG53751.1 - 0.049 14.0 1.1 0.049 14.0 1.1 2.2 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease FA_desaturase PF00487.24 KXG53752.1 - 6.4e-12 45.9 24.9 6.4e-12 45.9 24.9 2.1 1 1 1 2 2 2 1 Fatty acid desaturase TLD PF07534.16 KXG53753.1 - 8.1e-22 77.9 0.0 2.6e-21 76.3 0.0 1.9 2 0 0 2 2 2 1 TLD DUF1773 PF08593.10 KXG53753.1 - 0.052 14.6 0.8 0.14 13.3 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function SKA1 PF07160.12 KXG53754.1 - 5.3 6.8 9.2 15 5.3 9.2 1.8 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Abhydrolase_6 PF12697.7 KXG53755.1 - 1.4e-07 32.4 0.2 2.2e-07 31.7 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG53755.1 - 4e-05 23.0 0.0 0.00012 21.4 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KXG53755.1 - 0.0034 17.3 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KXG53755.1 - 0.0071 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hemerythrin PF01814.23 KXG53756.1 - 3.4e-12 47.1 0.1 4.8e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Spore_III_AB PF09548.10 KXG53756.1 - 0.14 12.2 0.5 1.6 8.8 0.1 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) TAXi_N PF14543.6 KXG53757.1 - 0.11 12.7 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal DSBA PF01323.20 KXG53758.1 - 5.2e-17 62.2 0.0 6e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain cobW PF02492.19 KXG53759.1 - 9.4e-41 139.3 0.0 1.5e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KXG53759.1 - 0.00084 19.2 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CobW_C PF07683.14 KXG53759.1 - 0.0026 17.6 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.6 KXG53759.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 KXG53759.1 - 0.038 13.4 0.2 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_16 PF13191.6 KXG53759.1 - 0.048 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 KXG53759.1 - 0.059 13.1 0.2 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KXG53759.1 - 0.085 13.4 0.1 0.3 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXG53759.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXG53759.1 - 0.16 11.8 0.4 1.3 8.8 0.2 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Orn_Arg_deC_N PF02784.16 KXG53760.1 - 1.8e-81 273.1 0.0 2.4e-81 272.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KXG53760.1 - 6.5e-20 71.2 0.0 1.1e-19 70.5 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Methyltransf_16 PF10294.9 KXG53761.1 - 1.9e-52 177.5 0.0 3e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KXG53761.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KXG53761.1 - 0.031 13.6 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_25 PF13649.6 KXG53761.1 - 0.041 14.6 0.0 0.11 13.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 KXG53761.1 - 0.1 11.9 0.1 0.22 10.8 0.1 1.5 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 KXG53764.1 - 0.00019 22.1 0.1 0.0003 21.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG53764.1 - 0.023 15.5 0.2 0.036 14.8 0.2 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXG53764.1 - 0.042 14.5 0.0 0.07 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KXG53764.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXG53764.1 - 0.23 11.3 2.2 0.95 9.2 2.2 1.8 1 1 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 KXG53765.1 - 2.1e-05 24.5 11.1 3.4e-05 23.9 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain M16C_assoc PF08367.11 KXG53766.1 - 5e-74 248.6 0.0 8.5e-74 247.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KXG53766.1 - 2e-19 70.3 0.0 3.7e-13 49.9 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXG53766.1 - 5.2e-09 36.3 0.0 2.6e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Taxilin PF09728.9 KXG53767.1 - 8.7e-85 284.6 57.4 8.3e-57 192.7 27.1 2.5 3 0 0 3 3 3 2 Myosin-like coiled-coil protein UPF0242 PF06785.11 KXG53767.1 - 0.59 10.2 50.4 0.11 12.6 9.9 3.5 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus SLATT_4 PF18186.1 KXG53767.1 - 0.95 9.1 16.6 0.61 9.7 2.3 3.2 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 Laminin_II PF06009.12 KXG53767.1 - 2 8.4 31.7 2.1 8.4 6.4 4.0 2 2 2 4 4 4 0 Laminin Domain II ADIP PF11559.8 KXG53767.1 - 2.4 8.2 50.8 1.3 9.1 9.7 4.3 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding NCD2 PF04905.13 KXG53767.1 - 7.6 6.5 15.2 0.25 11.3 1.1 3.3 2 1 2 4 4 4 0 NAB conserved region 2 (NCD2) NMO PF03060.15 KXG53768.1 - 9.4e-52 176.4 1.2 1.4e-51 175.8 1.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXG53768.1 - 7.1e-10 38.4 0.5 2e-09 36.9 0.5 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXG53768.1 - 0.0079 15.3 2.3 0.012 14.6 2.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PEP_hydrolase PF09370.10 KXG53768.1 - 0.086 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like DNA_pol_E_B PF04042.16 KXG53769.1 - 3.6e-44 150.6 0.0 6.3e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KXG53769.1 - 2.5e-37 127.9 0.0 3.9e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Acetyltransf_3 PF13302.7 KXG53770.1 - 1.5e-20 74.3 0.0 2e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXG53770.1 - 0.019 14.6 0.2 1.1 9.0 0.3 2.6 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Glyco_hydro_61 PF03443.14 KXG53771.1 - 7e-68 228.6 0.1 8.5e-68 228.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 KXG53771.1 - 0.27 11.5 2.2 1 9.7 0.0 2.5 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase GSu_C4xC__C2xCH PF09698.10 KXG53771.1 - 1.5 9.7 6.1 1.4 9.8 0.8 3.0 3 0 0 3 3 3 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Ribosomal_L38e PF01781.18 KXG53773.1 - 9.9e-33 112.1 2.5 1.1e-32 111.9 2.5 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family NTF2 PF02136.20 KXG53774.1 - 3.1e-07 31.0 0.5 1.2e-06 29.0 0.5 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KXG53774.1 - 0.0012 18.8 0.0 0.0025 17.7 0.0 1.7 1 1 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 tRNA-synt_1g PF09334.11 KXG53775.1 - 1.6e-94 316.9 0.0 5.6e-93 311.8 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KXG53775.1 - 7.4e-22 77.3 0.2 2.6e-11 42.5 0.0 3.3 1 1 2 4 4 4 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KXG53775.1 - 8.4e-11 41.8 0.0 1.2e-05 24.8 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 KXG53775.1 - 0.0049 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA PALP PF00291.25 KXG53776.1 - 1e-48 166.3 1.0 1.3e-48 166.0 0.3 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme PPTA PF01239.22 KXG53777.1 - 6.9e-34 114.6 24.8 1e-07 31.4 1.3 5.6 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_14 PF13428.6 KXG53777.1 - 0.0046 17.7 1.2 0.29 12.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4269 PF14091.6 KXG53777.1 - 0.097 12.9 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) DUF4614 PF15391.6 KXG53777.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Sulfatase PF00884.23 KXG53778.1 - 2.3e-22 79.8 0.1 3.6e-21 75.8 0.1 2.3 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KXG53778.1 - 1.2e-07 31.7 0.0 2.5e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KXG53778.1 - 0.0013 17.4 0.1 0.0018 17.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF924 PF06041.11 KXG53779.1 - 2.4e-53 180.9 0.0 2.9e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) DUF1940 PF09155.10 KXG53779.1 - 0.037 14.2 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) Fungal_trans_2 PF11951.8 KXG53780.1 - 9.5e-24 83.9 1.8 4.8e-15 55.3 0.2 2.7 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG53780.1 - 6.7e-08 32.5 8.4 1.2e-07 31.8 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 KXG53782.1 - 3e-52 178.1 0.0 4e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG53782.1 - 2.8e-06 27.4 0.0 0.0025 17.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold CPSase_L_D2 PF02786.17 KXG53783.1 - 3.7e-78 261.9 0.1 5.9e-78 261.2 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KXG53783.1 - 1.8e-66 223.7 0.0 3.4e-66 222.8 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KXG53783.1 - 5.3e-40 136.4 0.0 1e-39 135.5 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KXG53783.1 - 1.1e-30 105.9 0.0 2.9e-30 104.5 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KXG53783.1 - 4.6e-26 92.0 0.0 9.7e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KXG53783.1 - 4.8e-17 61.6 3.4 5.7e-17 61.3 1.4 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KXG53783.1 - 8.4e-10 38.3 2.7 0.00022 21.0 0.1 3.4 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KXG53783.1 - 1.8e-08 34.2 0.0 3.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXG53783.1 - 1.1e-07 31.6 0.0 2.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KXG53783.1 - 2.9e-06 27.4 0.0 9e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain HlyD_3 PF13437.6 KXG53783.1 - 0.0066 17.1 0.1 17 6.2 0.0 3.4 3 0 0 3 3 3 0 HlyD family secretion protein HlyD_D23 PF16576.5 KXG53783.1 - 0.0074 15.5 0.0 0.28 10.4 0.0 2.4 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion GARS_A PF01071.19 KXG53783.1 - 0.03 14.1 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RnfC_N PF13375.6 KXG53783.1 - 0.096 12.7 0.9 0.67 10.0 0.9 2.3 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Clathrin PF00637.20 KXG53784.1 - 4.8e-198 649.0 36.1 8.9e-32 109.9 0.7 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KXG53784.1 - 1.8e-38 129.0 0.4 5.1e-09 36.0 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KXG53784.1 - 3.1e-30 103.9 1.6 9.1e-30 102.4 0.3 2.6 2 0 0 2 2 2 1 Clathrin-H-link TPR_7 PF13176.6 KXG53784.1 - 0.0016 18.3 1.7 64 3.9 0.0 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXG53784.1 - 0.0055 16.8 6.1 0.38 11.1 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXG53784.1 - 0.014 16.1 9.0 1.8 9.6 0.1 6.7 7 0 0 7 7 4 0 Tetratricopeptide repeat Vps39_1 PF10366.9 KXG53784.1 - 0.064 13.5 8.6 15 6.0 0.0 6.0 4 1 1 5 5 5 0 Vacuolar sorting protein 39 domain 1 TPR_1 PF00515.28 KXG53784.1 - 0.07 13.0 0.4 6.6 6.7 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Pox_F16 PF04708.12 KXG53784.1 - 0.074 12.5 0.6 0.19 11.1 0.6 1.7 1 0 0 1 1 1 0 Poxvirus F16 protein TPR_2 PF07719.17 KXG53784.1 - 0.12 12.6 3.8 7.8 6.9 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXG53784.1 - 0.26 11.6 4.1 46 4.4 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Rop PF01815.16 KXG53784.1 - 0.5 10.3 3.5 0.39 10.6 0.2 2.5 2 0 0 2 2 2 0 Rop protein Utp13 PF08625.11 KXG53784.1 - 5.3 6.9 10.7 16 5.4 0.2 5.2 4 1 1 5 5 5 0 Utp13 specific WD40 associated domain Sugar_tr PF00083.24 KXG53785.1 - 9.1e-30 103.9 27.0 2.1e-27 96.1 27.0 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG53785.1 - 1.9e-29 102.7 32.7 2.1e-24 86.1 11.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L5_C PF00673.21 KXG53786.1 - 7.6e-22 77.3 0.0 1.1e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KXG53786.1 - 4.5e-18 65.3 0.0 1.9e-17 63.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 KXG53787.1 - 4.5e-11 42.3 0.0 5.8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain MPC PF03650.13 KXG53788.1 - 7.6e-36 122.6 0.1 9.1e-36 122.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Aa_trans PF01490.18 KXG53789.1 - 1.3e-85 287.6 32.1 1.6e-85 287.3 32.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.21 KXG53790.1 - 1.6e-55 188.6 32.3 2e-55 188.3 32.3 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KXG53790.1 - 7.6e-21 74.6 0.6 6.8e-07 28.7 0.1 3.2 3 0 0 3 3 3 3 Solute carrier family 12 GHMP_kinases_N PF00288.26 KXG53791.1 - 2.4e-15 56.5 0.0 5.5e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXG53791.1 - 3e-07 30.7 0.0 1.1e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KXG53791.1 - 0.0014 18.2 0.1 0.0028 17.2 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Alpha-L-AF_C PF06964.12 KXG53792.1 - 9.9e-24 84.3 0.0 2.4e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 KXG53792.1 - 0.064 13.5 3.1 0.1 12.8 0.6 2.4 3 0 0 3 3 3 0 Carbohydrate binding domain CoA_transf_3 PF02515.17 KXG53793.1 - 9.3e-39 133.6 1.5 4.1e-38 131.5 0.9 2.0 1 1 0 2 2 2 1 CoA-transferase family III LysM PF01476.20 KXG53794.1 - 2.3e-07 30.7 0.0 3.3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 LysM domain NmrA PF05368.13 KXG53795.1 - 1.4e-17 64.1 0.1 2e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG53795.1 - 1.7e-13 50.9 0.0 2.7e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXG53795.1 - 2.1e-05 24.1 0.2 7.3e-05 22.3 0.2 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXG53795.1 - 0.00057 19.1 0.0 0.00082 18.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KXG53795.1 - 0.003 17.0 0.1 0.051 13.0 0.2 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXG53795.1 - 0.013 15.0 0.4 0.026 14.0 0.4 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KXG53795.1 - 0.018 15.3 0.3 0.03 14.6 0.3 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KXG53795.1 - 0.043 13.7 0.2 0.062 13.2 0.2 1.2 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.20 KXG53795.1 - 0.15 12.1 0.6 0.5 10.4 0.4 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MNSV_P7B PF06692.11 KXG53796.1 - 0.18 11.8 0.0 0.68 10.0 0.0 1.9 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein eIF-3c_N PF05470.12 KXG53797.1 - 9.3e-166 552.6 17.9 9.3e-166 552.6 17.9 2.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KXG53797.1 - 3.1e-12 46.9 1.9 2e-11 44.3 0.0 3.1 2 1 1 3 3 3 1 PCI domain DUF1385 PF07136.11 KXG53797.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) RRP7 PF12923.7 KXG53797.1 - 0.043 14.0 3.8 4.2 7.5 2.0 2.7 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain MCPsignal PF00015.21 KXG53797.1 - 5.9 6.7 7.9 0.52 10.1 0.3 2.7 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CDC45 PF02724.14 KXG53797.1 - 7.1 4.8 11.9 14 3.8 11.9 1.5 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 KXG53798.1 - 1.2e-48 165.8 0.1 4.3e-48 164.0 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG53798.1 - 4.9e-21 75.2 0.0 9.4e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXG53798.1 - 0.0016 18.4 1.4 0.0017 18.3 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXG53798.1 - 0.011 15.3 0.3 0.069 12.7 0.0 2.0 1 1 1 2 2 2 0 RIO1 family Kdo PF06293.14 KXG53798.1 - 0.13 11.6 0.2 0.66 9.3 0.0 2.1 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family SNF2_N PF00176.23 KXG53799.1 - 3.6e-67 226.6 0.0 5.6e-67 225.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXG53799.1 - 2e-18 66.7 0.0 1e-17 64.5 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KXG53799.1 - 3.7e-06 26.3 0.1 8.9e-06 25.1 0.1 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KXG53799.1 - 4e-06 26.9 0.3 1.2e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RR_TM4-6 PF06459.12 KXG53801.1 - 0.81 9.5 4.7 1.1 9.0 4.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Apt1 PF10351.9 KXG53801.1 - 4.3 6.1 7.9 5.2 5.8 7.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain NPR3 PF03666.13 KXG53801.1 - 5.7 5.6 6.7 9.8 4.8 6.3 1.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Med27 PF11571.8 KXG53803.1 - 1.3e-19 70.3 0.0 2.4e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 27 2OG-FeII_Oxy_3 PF13640.6 KXG53804.1 - 3.3e-06 27.9 0.0 1.1e-05 26.2 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosomal_L27 PF01016.19 KXG53804.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L27 protein MFS_1 PF07690.16 KXG53806.1 - 1.1e-34 119.9 104.5 6.5e-22 77.9 47.2 3.5 3 1 1 4 4 4 3 Major Facilitator Superfamily Flagellin_N PF00669.20 KXG53807.1 - 0.0044 17.1 0.2 0.39 10.8 0.0 2.0 1 1 1 2 2 2 2 Bacterial flagellin N-terminal helical region TipAS PF07739.13 KXG53807.1 - 0.04 14.5 0.1 1.3 9.6 0.0 2.0 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain BRX_N PF13713.6 KXG53807.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain PXA PF02194.15 KXG53807.1 - 0.082 12.9 0.1 0.097 12.6 0.1 1.2 1 0 0 1 1 1 0 PXA domain DUF3349 PF11829.8 KXG53807.1 - 0.11 13.3 0.3 0.23 12.3 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) APH PF01636.23 KXG53808.1 - 3.3e-09 37.0 0.0 2.5e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1857 PF08982.11 KXG53810.1 - 4.4e-50 169.4 0.1 4.9e-50 169.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Mannosidase_ig PF17786.1 KXG53810.1 - 0.1 13.2 0.1 0.17 12.5 0.1 1.3 1 0 0 1 1 1 0 Mannosidase Ig/CBM-like domain TrkH PF02386.16 KXG53811.1 - 3e-109 365.7 8.6 7e-107 357.9 3.8 2.0 2 0 0 2 2 2 2 Cation transport protein PhzC-PhzF PF02567.16 KXG53812.1 - 3.2e-44 151.5 0.0 3.9e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein TIMELESS PF04821.14 KXG53813.1 - 4.5e-90 301.7 0.0 1.5e-89 300.0 0.0 2.0 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 KXG53813.1 - 6.5e-64 217.1 35.9 4.9e-61 207.6 2.4 4.2 2 1 1 3 3 3 2 Timeless protein C terminal region 3HCDH_N PF02737.18 KXG53814.1 - 3.7e-51 173.6 1.4 4.8e-51 173.2 1.4 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXG53814.1 - 1.5e-33 115.2 0.1 4.6e-33 113.7 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KXG53814.1 - 0.00039 20.6 0.8 0.00078 19.6 0.3 1.8 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 KXG53814.1 - 0.00059 20.1 0.4 0.0015 18.8 0.4 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 KXG53814.1 - 0.011 15.4 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 KXG53814.1 - 0.012 15.3 0.4 0.026 14.2 0.1 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KXG53814.1 - 0.012 14.9 0.2 0.022 14.0 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KXG53814.1 - 0.037 13.2 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXG53814.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KXG53814.1 - 0.088 12.2 0.1 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXG53814.1 - 0.43 11.2 2.4 0.77 10.4 0.5 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Actin PF00022.19 KXG53815.1 - 7.5e-105 350.8 0.0 4.2e-104 348.4 0.0 1.8 1 1 0 1 1 1 1 Actin Abhydrolase_1 PF00561.20 KXG53816.1 - 1.8e-13 50.8 0.0 8e-11 42.1 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG53816.1 - 3.8e-07 30.9 0.2 9.5e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG53816.1 - 1.5e-06 27.6 0.0 3.2e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXG53816.1 - 2.6e-05 23.1 0.0 5.1e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Ndr family DUF5453 PF17534.2 KXG53816.1 - 0.0045 17.0 11.3 0.0075 16.3 11.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5453) GCIP PF13324.6 KXG53817.1 - 1.8e-24 86.8 7.2 3.5e-24 85.8 7.2 1.4 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting PEX11 PF05648.14 KXG53817.1 - 0.011 15.3 0.2 0.057 12.9 0.0 2.0 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Sigma70_ner PF04546.13 KXG53817.1 - 0.24 11.3 6.5 0.12 12.3 3.1 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4611 PF15387.6 KXG53817.1 - 2.3 8.5 11.0 0.19 11.9 3.1 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) FAM176 PF14851.6 KXG53817.1 - 3.2 7.4 5.5 3 7.5 1.8 2.2 2 0 0 2 2 2 0 FAM176 family YL1 PF05764.13 KXG53817.1 - 5.3 7.1 11.1 0.31 11.1 5.4 1.8 2 0 0 2 2 2 0 YL1 nuclear protein LRR_4 PF12799.7 KXG53818.1 - 2.4e-32 110.4 53.3 2.9e-07 30.7 1.2 10.6 5 5 8 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXG53818.1 - 1.1e-25 89.2 48.6 6.3e-09 35.5 4.4 8.2 5 2 4 9 9 9 8 Leucine rich repeat LRR_9 PF14580.6 KXG53818.1 - 9.8e-09 35.0 19.2 0.075 12.5 3.0 5.4 2 2 2 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 KXG53818.1 - 1.3e-06 28.1 41.0 2.3 9.1 0.2 12.7 13 2 0 13 13 13 5 Leucine Rich Repeat LRR_6 PF13516.6 KXG53818.1 - 6.9e-05 22.6 29.7 5.8 7.2 0.0 9.6 10 0 0 10 10 10 4 Leucine Rich repeat CSTF_C PF14304.6 KXG53818.1 - 0.0087 15.6 0.1 0.046 13.3 0.1 2.3 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal Ribosomal_L13e PF01294.18 KXG53820.1 - 7.6e-75 250.7 5.6 1.1e-74 250.2 5.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e THOC7 PF05615.13 KXG53821.1 - 0.048 13.9 0.2 0.32 11.3 0.2 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 Oxidored-like PF09791.9 KXG53822.1 - 1.1e-23 82.6 3.1 3e-23 81.2 3.1 1.8 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 KXG53822.1 - 0.035 14.1 2.2 0.07 13.1 2.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5522) p450 PF00067.22 KXG53823.1 - 1.2e-69 235.3 0.0 1.5e-69 235.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3245 PF11595.8 KXG53824.1 - 1.3e-47 162.0 11.7 3.5e-47 160.6 11.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3245) Ribosomal_60s PF00428.19 KXG53824.1 - 0.0086 16.6 12.3 0.0086 16.6 12.3 3.6 2 1 1 3 3 3 1 60s Acidic ribosomal protein HSF_DNA-bind PF00447.17 KXG53825.1 - 2.8e-30 104.8 0.1 4.8e-30 104.0 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding F-box PF00646.33 KXG53826.1 - 1.8e-07 30.9 0.2 1.8e-07 30.9 0.2 2.4 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KXG53826.1 - 9.1e-07 28.7 0.1 1.8e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like FAM198 PF15051.6 KXG53826.1 - 0.043 12.7 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 FAM198 protein F-box_4 PF15966.5 KXG53826.1 - 0.048 13.6 0.1 0.14 12.1 0.1 1.8 1 0 0 1 1 1 0 F-box ATP-grasp_2 PF08442.10 KXG53827.1 - 2.1e-74 249.5 0.6 3.6e-74 248.7 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain adh_short PF00106.25 KXG53827.1 - 1.3e-35 122.6 0.9 2e-34 118.8 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG53827.1 - 2e-24 86.4 0.0 1.8e-23 83.3 0.0 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ligase_CoA PF00549.19 KXG53827.1 - 2.1e-24 86.1 0.3 3.7e-24 85.3 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KXG53827.1 - 4e-08 33.0 0.1 1.2e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KXG53827.1 - 0.019 14.8 1.2 0.41 10.4 0.1 2.6 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NmrA PF05368.13 KXG53827.1 - 0.071 12.7 0.0 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family DUF1776 PF08643.10 KXG53827.1 - 0.085 12.2 0.1 0.38 10.1 0.1 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) DNA_pol_lambd_f PF10391.9 KXG53827.1 - 0.092 12.6 0.0 4.5 7.2 0.0 2.7 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda SLAC1 PF03595.17 KXG53828.1 - 6.3e-76 255.7 48.1 7.3e-76 255.5 48.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Hist_deacetyl PF00850.19 KXG53829.1 - 2.5e-49 168.4 0.0 5.2e-49 167.4 0.0 1.5 1 1 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.11 KXG53829.1 - 0.022 14.7 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 RTP801 C-terminal region Ala_racemase_N PF01168.20 KXG53831.1 - 5.5e-21 75.2 0.0 6.8e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.20 KXG53832.1 - 2.4e-124 415.8 4.4 3.2e-124 415.4 4.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KXG53832.1 - 4.9e-44 149.1 0.0 1.2e-43 147.9 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KXG53832.1 - 2.1e-16 60.2 0.0 5.4e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain RTP1_C1 PF10363.9 KXG53832.1 - 0.11 12.7 0.4 0.59 10.3 0.1 2.5 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Homeodomain PF00046.29 KXG53834.1 - 1.2e-16 60.3 4.1 2.3e-16 59.4 4.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXG53834.1 - 0.06 13.2 0.2 0.21 11.5 0.2 2.0 1 0 0 1 1 1 0 Homeobox KN domain efThoc1 PF11957.8 KXG53835.1 - 8.9e-150 499.6 4.8 8.9e-150 499.6 4.8 1.6 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor Aquarius_N PF16399.5 KXG53836.1 - 0 1061.7 0.1 0 1061.4 0.1 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KXG53836.1 - 3.2e-26 92.2 0.0 5.5e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXG53836.1 - 6.5e-21 75.3 0.0 2.5e-20 73.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXG53836.1 - 1.2e-07 31.7 0.0 0.00031 20.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KXG53836.1 - 1.7e-06 28.4 0.0 5e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KXG53836.1 - 3.7e-06 27.1 0.0 8.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KXG53836.1 - 0.00052 19.8 0.0 0.1 12.3 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KXG53836.1 - 0.0025 17.6 1.2 0.037 13.8 0.3 2.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain DnaB_C PF03796.15 KXG53836.1 - 0.0027 17.1 0.0 0.03 13.7 0.0 2.2 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KXG53836.1 - 0.0035 17.7 0.1 0.021 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KXG53836.1 - 0.015 15.7 0.0 0.06 13.8 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KXG53836.1 - 0.025 14.1 0.0 0.097 12.2 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KXG53836.1 - 0.032 13.5 1.0 0.064 12.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KXG53836.1 - 0.059 13.6 0.2 0.34 11.2 0.2 2.3 1 1 1 2 2 2 0 AAA domain DEAD PF00270.29 KXG53836.1 - 0.079 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase PIF1 PF05970.14 KXG53836.1 - 0.082 12.1 0.0 3.8 6.6 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_5 PF07728.14 KXG53836.1 - 0.1 12.6 0.0 0.54 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.15 KXG53836.1 - 0.13 11.1 0.0 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_7 PF12775.7 KXG53836.1 - 0.18 11.3 0.0 0.41 10.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region 4HBT PF03061.22 KXG53837.1 - 9.7e-15 54.7 0.1 1.5e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KXG53837.1 - 0.052 13.8 0.0 0.057 13.7 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF4442 PF14539.6 KXG53837.1 - 0.062 13.4 0.0 0.086 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Tfb2 PF03849.14 KXG53838.1 - 6.7e-136 452.9 0.0 1.1e-135 452.2 0.0 1.3 2 0 0 2 2 2 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KXG53838.1 - 7.5e-24 84.0 0.6 1.4e-23 83.1 0.6 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KXG53838.1 - 4.8e-05 23.5 0.0 0.00047 20.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Fungal_trans_2 PF11951.8 KXG53839.1 - 2.3e-05 23.4 4.7 2.3e-05 23.4 4.7 1.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 KXG53840.1 - 2.5e-73 246.8 0.0 2.9e-73 246.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DIOX_N PF14226.6 KXG53841.1 - 2.1e-17 63.9 0.2 3.5e-17 63.2 0.2 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG53841.1 - 3.4e-13 49.9 0.0 5.9e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KXG53842.1 - 5.7e-32 111.0 29.2 7.3e-32 110.7 29.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG53842.1 - 1.3e-07 30.9 10.5 0.00015 20.8 3.3 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter Ada_Zn_binding PF02805.16 KXG53843.1 - 7.4e-28 96.4 3.6 1.3e-27 95.6 3.6 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KXG53843.1 - 1e-07 31.9 0.0 2.9e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KXG53843.1 - 0.0026 18.0 0.1 0.0071 16.6 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KXG53843.1 - 0.049 13.4 0.1 0.19 11.6 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain zf-AN1 PF01428.16 KXG53846.1 - 4e-23 81.3 25.7 2.3e-12 46.9 7.6 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger zf-C5HC2 PF02928.16 KXG53846.1 - 0.00067 20.0 8.9 0.21 12.0 0.6 2.5 2 0 0 2 2 2 2 C5HC2 zinc finger IBR PF01485.21 KXG53846.1 - 0.0085 16.3 6.2 0.0085 16.3 6.2 2.7 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 KXG53846.1 - 0.089 13.2 13.5 0.48 10.8 2.3 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain C1_4 PF07975.12 KXG53846.1 - 1.4 9.2 18.5 5.5 7.3 3.8 3.2 2 2 0 2 2 2 0 TFIIH C1-like domain zinc_ribbon_4 PF13717.6 KXG53846.1 - 3.2 7.7 8.4 1.3 9.0 0.7 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Thymidylat_synt PF00303.19 KXG53847.1 - 3.8e-103 344.3 0.0 4.4e-103 344.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase TGT PF01702.18 KXG53848.1 - 6.1e-141 469.6 0.0 7.1e-141 469.4 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MFS_1 PF07690.16 KXG53849.1 - 3.5e-26 92.0 32.5 3.5e-26 92.0 32.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2975 PF11188.8 KXG53849.1 - 0.083 12.8 0.1 0.083 12.8 0.1 3.4 4 1 1 5 5 5 0 Protein of unknown function (DUF2975) R3H-assoc PF13902.6 KXG53851.1 - 1.4e-23 83.7 2.2 3.7e-23 82.4 2.2 1.8 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 KXG53851.1 - 0.012 15.6 0.1 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 R3H domain Peptidase_M28 PF04389.17 KXG53852.1 - 4.7e-29 101.5 0.1 1e-28 100.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXG53852.1 - 7.4e-09 35.6 0.1 1.6e-08 34.5 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Cupin_3 PF05899.12 KXG53853.1 - 1.5e-05 24.6 0.0 2.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 KXG53853.1 - 0.00016 21.5 0.0 0.0002 21.2 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Inositol_P PF00459.25 KXG53854.1 - 1.7e-38 132.7 0.0 3.7e-38 131.6 0.0 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family Chitin_synth_1 PF01644.17 KXG53855.1 - 2.1e-77 258.7 0.0 3.3e-77 258.0 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase DUF1774 PF08611.10 KXG53855.1 - 3.2e-32 110.7 3.0 3.2e-32 110.7 3.0 2.4 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Chitin_synth_1N PF08407.11 KXG53855.1 - 4.6e-26 90.6 0.1 9.2e-26 89.6 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KXG53855.1 - 3.3e-23 82.1 2.3 8.4e-20 70.9 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXG53855.1 - 3.9e-07 30.2 0.2 3.9e-07 30.2 0.2 3.7 3 2 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXG53855.1 - 0.011 15.6 0.0 0.062 13.2 0.0 2.1 1 1 1 2 2 2 0 Glycosyltransferase like family 2 Caps_synth_CapC PF14102.6 KXG53855.1 - 0.024 15.1 0.4 0.024 15.1 0.4 3.8 4 0 0 4 4 4 0 Capsule biosynthesis CapC MFS_1 PF07690.16 KXG53857.1 - 2.2e-30 105.8 55.5 6.1e-25 87.9 42.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_3 PF13302.7 KXG53857.1 - 2.8e-15 57.2 0.0 6e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG53857.1 - 0.00017 21.8 0.0 0.00039 20.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KXG53857.1 - 0.012 15.8 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Catalase PF00199.19 KXG53858.1 - 1.1e-166 554.7 0.1 1.5e-166 554.3 0.1 1.1 1 0 0 1 1 1 1 Catalase Amidase PF01425.21 KXG53858.1 - 3.5e-101 339.4 0.0 5.4e-101 338.8 0.0 1.3 1 0 0 1 1 1 1 Amidase Cation_efflux PF01545.21 KXG53858.1 - 4.8e-46 157.0 6.2 8.6e-46 156.2 6.2 1.4 1 0 0 1 1 1 1 Cation efflux family Catalase-rel PF06628.12 KXG53858.1 - 4.4e-19 68.5 0.1 9.3e-19 67.4 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KXG53858.1 - 2.3e-08 33.8 0.2 5.1e-08 32.7 0.2 1.6 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KXG53858.1 - 2.2e-07 30.8 0.0 4.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family BPD_transp_2 PF02653.16 KXG53858.1 - 0.071 12.3 1.1 0.13 11.4 1.1 1.4 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Potyvirid-P3 PF13608.6 KXG53858.1 - 0.19 10.8 0.0 0.49 9.4 0.0 1.6 2 0 0 2 2 2 0 Protein P3 of Potyviral polyprotein AFG1_ATPase PF03969.16 KXG53859.1 - 1.7e-97 326.6 0.0 9e-93 311.0 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.6 KXG53859.1 - 0.00036 20.8 0.0 0.0028 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXG53859.1 - 0.0011 19.4 0.1 0.47 10.8 0.0 3.4 3 1 1 4 4 4 1 AAA ATPase domain AAA PF00004.29 KXG53859.1 - 0.0016 18.9 0.0 0.041 14.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 KXG53859.1 - 0.0075 16.1 0.5 1.7 8.5 0.1 2.3 2 1 0 2 2 2 2 Bacterial dnaA protein RNA_helicase PF00910.22 KXG53859.1 - 0.014 15.8 0.0 0.11 12.9 0.0 2.4 3 0 0 3 3 3 0 RNA helicase AAA_14 PF13173.6 KXG53859.1 - 0.014 15.4 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXG53859.1 - 0.19 11.1 0.0 0.65 9.3 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SH3_1 PF00018.28 KXG53860.1 - 3.9e-26 90.4 0.0 1.3e-11 43.9 0.0 2.8 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KXG53860.1 - 4.8e-15 55.2 0.1 4.5e-07 29.6 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KXG53860.1 - 8.1e-14 51.6 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 KXG53860.1 - 1.9e-08 33.9 0.0 6.9e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 KXG53860.1 - 4.5e-07 29.7 0.5 9.3e-07 28.7 0.5 1.5 1 0 0 1 1 1 1 PB1 domain SAC3_GANP PF03399.16 KXG53861.1 - 1e-23 84.2 0.8 1.6e-21 77.0 0.8 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KXG53861.1 - 0.0011 18.9 0.1 0.0026 17.8 0.1 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family EAP30 PF04157.16 KXG53862.1 - 1.6e-40 138.9 0.1 2.2e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KXG53862.1 - 7.9e-23 80.5 0.0 1.4e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 KXG53862.1 - 2.8e-22 77.9 2.7 2.8e-22 77.9 2.7 2.2 2 0 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 KXG53862.1 - 5.6e-05 22.4 12.5 0.00025 20.3 1.5 2.8 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 KXG53862.1 - 0.00021 21.3 4.6 0.0028 17.7 0.4 2.5 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger GRAM PF02893.20 KXG53862.1 - 0.0027 17.6 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Fungal_trans PF04082.18 KXG53863.1 - 2.8e-12 46.3 0.9 5.3e-12 45.3 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ketoacyl-synt PF00109.26 KXG53864.1 - 2.8e-64 217.1 0.0 9.9e-64 215.3 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KXG53864.1 - 2.8e-64 217.2 0.0 4.8e-64 216.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KXG53864.1 - 6.3e-57 192.4 0.0 2.7e-56 190.3 0.0 2.2 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KXG53864.1 - 4.3e-50 171.0 0.1 7.3e-50 170.3 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXG53864.1 - 1.3e-28 99.3 0.1 3.5e-28 98.0 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXG53864.1 - 2.3e-18 66.7 0.0 6.5e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KXG53864.1 - 5e-10 39.2 0.0 1.1e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 KXG53864.1 - 3.9e-05 23.9 0.1 0.0001 22.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KXG53864.1 - 0.00024 20.6 0.1 0.00061 19.2 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 KXG53864.1 - 0.0021 17.9 0.0 0.0066 16.3 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.10 KXG53864.1 - 0.0084 15.9 1.3 0.043 13.7 0.4 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N PF00107.26 KXG53864.1 - 0.017 15.1 0.0 0.93 9.5 0.0 3.0 3 0 0 3 3 2 0 Zinc-binding dehydrogenase Ribonuc_L-PSP PF01042.21 KXG53866.1 - 4.1e-36 123.7 0.0 4.8e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DIT1_PvcA PF05141.12 KXG53868.1 - 4e-61 206.9 0.0 4.7e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein MFS_1 PF07690.16 KXG53869.1 - 4.7e-24 85.0 36.6 7.7e-24 84.3 36.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DJ-1_PfpI PF01965.24 KXG53869.1 - 4.2e-05 23.4 0.0 0.00018 21.4 0.0 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family DIT1_PvcA PF05141.12 KXG53870.1 - 2.9e-75 253.3 0.0 3.9e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein FAM193_C PF15914.5 KXG53870.1 - 0.022 14.5 0.1 0.06 13.1 0.1 1.7 1 1 0 1 1 1 0 FAM193 family C-terminal MTP18 PF10558.9 KXG53871.1 - 3.1e-82 274.6 0.2 9.8e-82 273.0 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial 18 KDa protein (MTP18) ATP19 PF11022.8 KXG53872.1 - 4.8e-29 100.5 0.1 5.6e-29 100.3 0.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit K ACPS PF01648.20 KXG53873.1 - 8.8e-13 48.4 0.0 1.2e-12 47.9 0.0 1.3 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 KXG53873.1 - 0.026 14.6 0.2 5 7.3 0.0 2.3 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain PHP PF02811.19 KXG53874.1 - 2.2e-15 57.3 0.0 7.4e-15 55.6 0.0 1.8 1 1 0 1 1 1 1 PHP domain FKBP_C PF00254.28 KXG53875.1 - 1.2e-24 86.5 0.0 1.4e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase COesterase PF00135.28 KXG53876.1 - 1.6e-76 258.3 0.0 6.2e-75 253.0 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG53876.1 - 2.3e-05 24.4 0.0 8.4e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXG53876.1 - 0.0012 18.4 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AAA PF00004.29 KXG53878.1 - 7.5e-37 126.7 0.0 1.7e-36 125.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXG53878.1 - 1.2e-08 34.6 0.0 2.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KXG53878.1 - 2.9e-05 24.5 0.2 0.00095 19.6 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXG53878.1 - 3.4e-05 23.6 0.0 7.2e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KXG53878.1 - 5e-05 23.3 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXG53878.1 - 5.8e-05 23.7 0.0 0.001 19.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXG53878.1 - 7.4e-05 22.8 0.2 0.00097 19.2 0.2 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXG53878.1 - 0.00015 22.0 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXG53878.1 - 0.00026 21.3 0.2 0.0065 16.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXG53878.1 - 0.00054 20.1 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXG53878.1 - 0.0008 18.8 0.1 0.0015 18.0 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXG53878.1 - 0.001 18.8 0.0 0.0028 17.4 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KXG53878.1 - 0.0011 19.3 0.0 0.0034 17.7 0.0 1.9 1 1 0 1 1 1 1 RNA helicase TniB PF05621.11 KXG53878.1 - 0.0017 17.8 0.0 1.7 8.0 0.0 2.6 1 1 1 2 2 2 2 Bacterial TniB protein AAA_25 PF13481.6 KXG53878.1 - 0.0026 17.4 0.2 0.051 13.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXG53878.1 - 0.0057 16.6 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 KXG53878.1 - 0.0076 16.5 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXG53878.1 - 0.01 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KXG53878.1 - 0.024 14.7 0.0 0.062 13.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 KXG53878.1 - 0.029 14.3 0.1 0.08 12.9 0.1 1.6 1 1 1 2 2 2 0 Rad17 P-loop domain Sigma54_activat PF00158.26 KXG53878.1 - 0.034 13.8 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 KXG53878.1 - 0.037 14.5 0.2 0.12 12.9 0.0 2.0 2 1 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 KXG53878.1 - 0.042 13.8 0.0 0.2 11.6 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea CPT PF07931.12 KXG53878.1 - 0.045 13.6 0.1 0.12 12.2 0.0 1.8 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein AAA_7 PF12775.7 KXG53878.1 - 0.049 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KXG53878.1 - 0.05 12.7 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 KXG53878.1 - 0.066 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 KXG53878.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KXG53878.1 - 0.12 11.7 0.0 0.55 9.5 0.0 2.0 1 1 1 2 2 2 0 KaiC Csm1 PF12539.8 KXG53879.1 - 1.1e-30 106.1 0.2 1.9e-30 105.3 0.2 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 AAA_13 PF13166.6 KXG53879.1 - 0.0043 15.8 3.4 0.0065 15.2 3.4 1.2 1 0 0 1 1 1 1 AAA domain APG6_N PF17675.1 KXG53879.1 - 0.0086 16.6 12.7 0.0086 16.6 12.7 2.1 3 0 0 3 3 1 1 Apg6 coiled-coil region SPATA1_C PF15743.5 KXG53879.1 - 0.037 14.1 6.1 0.085 12.9 6.1 1.7 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus Vps5 PF09325.10 KXG53879.1 - 0.087 12.4 5.2 0.18 11.3 4.7 1.7 1 1 0 1 1 1 0 Vps5 C terminal like I_LWEQ PF01608.17 KXG53879.1 - 0.13 12.5 11.1 0.072 13.3 8.1 2.1 2 0 0 2 2 1 0 I/LWEQ domain USP8_interact PF08941.10 KXG53879.1 - 0.19 11.5 0.1 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 USP8 interacting Taxilin PF09728.9 KXG53879.1 - 0.19 10.9 11.8 0.35 10.0 11.8 1.4 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF3138 PF11336.8 KXG53879.1 - 0.27 9.8 5.0 0.48 9.0 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Jnk-SapK_ap_N PF09744.9 KXG53879.1 - 0.36 11.1 9.0 5.3 7.2 2.6 3.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 KXG53879.1 - 0.92 8.8 15.2 1.3 8.3 11.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 KXG53879.1 - 1.5 7.6 16.1 6.8 5.5 16.2 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 KXG53879.1 - 1.8 8.4 14.9 3.4 7.4 12.2 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 COG2 PF06148.11 KXG53879.1 - 2.5 8.2 7.4 1.3 9.1 4.4 2.1 2 1 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4201 PF13870.6 KXG53879.1 - 3 7.5 14.0 0.27 11.0 1.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) ADIP PF11559.8 KXG53879.1 - 3.1 7.9 17.3 1.5 8.9 13.1 2.5 2 1 0 2 2 1 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 KXG53879.1 - 3.2 7.5 9.7 10 5.9 9.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 KXG53879.1 - 3.2 7.8 5.1 8.3 6.5 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 KXG53879.1 - 3.2 6.9 4.4 5.3 6.2 4.4 1.4 1 0 0 1 1 1 0 TMPIT-like protein DHR10 PF18595.1 KXG53879.1 - 4.1 7.5 20.8 5.4 7.1 2.4 3.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Fib_alpha PF08702.10 KXG53879.1 - 4.6 7.4 8.2 4 7.6 0.6 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.6 KXG53879.1 - 7.3 5.9 16.8 2 7.7 10.5 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PigN PF04987.14 KXG53880.1 - 1.2e-143 479.3 39.5 8.7e-101 338.0 14.5 2.5 2 1 1 3 3 3 2 Phosphatidylinositolglycan class N (PIG-N) Sulfatase PF00884.23 KXG53880.1 - 1.9e-10 40.7 0.1 3.3e-10 39.9 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXG53880.1 - 4.7e-08 33.0 5.8 1e-06 28.6 5.7 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KXG53880.1 - 0.00051 19.5 0.1 0.00082 18.8 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Fungal_trans PF04082.18 KXG53881.1 - 5.9e-34 117.3 0.0 1.8e-33 115.7 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4611 PF15387.6 KXG53882.1 - 0.001 19.3 3.2 0.0024 18.1 3.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Na_H_Exchanger PF00999.21 KXG53883.1 - 1.4e-30 106.4 33.7 2.7e-25 89.0 22.4 3.0 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family Fst_toxin PF13955.6 KXG53883.1 - 0.55 10.2 0.1 0.55 10.2 0.1 3.2 3 0 0 3 3 3 0 Toxin Fst, type I toxin-antitoxin system Cys_Met_Meta_PP PF01053.20 KXG53884.1 - 4.1e-142 473.3 0.0 5.2e-142 472.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 KXG53884.1 - 0.0003 19.4 0.0 0.00097 17.8 0.0 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 KXG53884.1 - 0.012 14.9 0.2 0.026 13.8 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KXG53884.1 - 0.043 13.1 0.1 0.11 11.7 0.1 1.6 2 0 0 2 2 2 0 Beta-eliminating lyase Ferric_reduct PF01794.19 KXG53885.1 - 6.2e-22 78.0 15.1 6.2e-22 78.0 15.1 2.5 2 1 1 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXG53885.1 - 7.7e-13 48.5 0.0 2e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KXG53885.1 - 1.2e-09 38.4 0.0 2.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.6 KXG53885.1 - 0.0062 17.1 14.7 0.052 14.1 2.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4405) PALP PF00291.25 KXG53886.1 - 7.5e-33 114.2 0.0 1.2e-32 113.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 KXG53886.1 - 3.2e-05 24.4 0.0 0.00011 22.7 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain MFS_1 PF07690.16 KXG53887.1 - 4.4e-42 144.3 42.1 5.1e-40 137.5 41.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG53887.1 - 4e-17 61.9 26.4 6.2e-17 61.2 26.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) IBR PF01485.21 KXG53888.1 - 0.00057 20.0 4.9 0.00057 20.0 4.9 4.8 4 1 0 4 4 4 3 IBR domain, a half RING-finger domain adh_short PF00106.25 KXG53889.1 - 1.1e-81 273.0 8.8 2.5e-44 151.1 0.7 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXG53889.1 - 4.5e-65 219.5 5.8 1.3e-34 119.7 0.3 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KXG53889.1 - 1.4e-33 115.1 0.0 2.6e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KXG53889.1 - 2.6e-24 86.1 5.6 1.2e-11 44.9 0.9 2.6 2 1 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 KXG53889.1 - 0.00054 19.3 0.4 0.0016 17.7 0.4 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.23 KXG53889.1 - 0.041 14.0 1.0 5.7 7.0 1.1 2.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain PRK PF00485.18 KXG53890.1 - 0.0063 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family KAP_NTPase PF07693.14 KXG53890.1 - 0.01 15.1 0.0 0.013 14.7 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain SRP_SPB PF02978.19 KXG53890.1 - 0.032 14.8 0.0 0.056 14.1 0.0 1.3 1 0 0 1 1 1 0 Signal peptide binding domain Zeta_toxin PF06414.12 KXG53890.1 - 0.033 13.4 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MeaB PF03308.16 KXG53890.1 - 0.045 12.7 0.0 0.37 9.7 0.0 2.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 KXG53890.1 - 0.069 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B HTH_3 PF01381.22 KXG53890.1 - 0.075 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix AAA_18 PF13238.6 KXG53890.1 - 0.11 13.1 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ribosomal_L30_N PF08079.12 KXG53891.1 - 2e-26 92.0 13.5 3.3e-26 91.3 13.5 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KXG53891.1 - 1.1e-17 63.6 1.9 3.2e-17 62.1 1.9 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e EAP30 PF04157.16 KXG53892.1 - 2.9e-69 232.9 0.0 3.3e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.7 KXG53892.1 - 0.04 13.8 0.3 0.16 11.9 0.1 2.1 3 0 0 3 3 3 0 MarR family Pribosyltran PF00156.27 KXG53893.1 - 5.4e-07 29.3 0.0 7.3e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DPM3 PF08285.11 KXG53894.1 - 3.6e-32 110.4 0.4 3.9e-32 110.3 0.4 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Phage_holin_3_6 PF07332.11 KXG53894.1 - 0.1 12.6 8.1 1.6 8.8 2.7 2.1 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF383 PF04063.14 KXG53895.1 - 0.016 14.9 0.1 2 8.1 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF383) KAP PF05804.12 KXG53895.1 - 0.018 13.2 0.0 0.062 11.4 0.0 1.8 2 0 0 2 2 2 0 Kinesin-associated protein (KAP) ABC1 PF03109.16 KXG53897.1 - 2e-21 76.4 0.1 1.6e-18 67.0 0.1 2.7 2 1 0 2 2 2 1 ABC1 family Raf1_HTH PF18579.1 KXG53897.1 - 0.013 15.1 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain RIO1 PF01163.22 KXG53897.1 - 0.02 14.5 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 KXG53897.1 - 0.087 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cyto_heme_lyase PF01265.17 KXG53898.1 - 1e-126 422.4 2.3 1.2e-126 422.2 2.3 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase UQ_con PF00179.26 KXG53899.1 - 5.3e-19 68.3 0.1 7.9e-19 67.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.23 KXG53900.1 - 8.6e-40 137.2 0.8 1.2e-39 136.7 0.8 1.2 1 0 0 1 1 1 1 Surface antigen Yip1 PF04893.17 KXG53900.1 - 4.3e-05 23.3 18.9 0.00073 19.3 18.9 2.2 1 1 0 1 1 1 1 Yip1 domain UFD1 PF03152.14 KXG53901.1 - 4.6e-27 94.6 0.0 6.1e-22 77.9 0.0 3.3 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KXG53901.1 - 9.3e-07 29.0 0.2 3.3e-06 27.2 0.2 1.9 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A TRAF6_Z2 PF18048.1 KXG53901.1 - 0.014 15.5 0.6 0.014 15.5 0.6 2.9 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-LYAR PF08790.11 KXG53901.1 - 0.061 13.2 4.6 2.1 8.3 0.1 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DUF608 PF04685.13 KXG53901.1 - 0.32 10.1 0.8 2.4 7.2 0.4 2.1 2 0 0 2 2 2 0 Glycosyl-hydrolase family 116, catalytic region Zn-ribbon_8 PF09723.10 KXG53901.1 - 1.3 9.2 15.7 0.32 11.1 2.6 3.8 2 1 2 4 4 4 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 KXG53901.1 - 8.6 6.4 10.0 14 5.7 0.2 3.5 4 0 0 4 4 4 0 zinc-ribbon domain F-box-like PF12937.7 KXG53902.1 - 0.0021 17.9 0.1 0.0045 16.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like zf-RING_13 PF17977.1 KXG53902.1 - 0.12 12.5 1.5 0.3 11.2 1.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain AAA PF00004.29 KXG53903.1 - 1e-42 145.7 0.0 1.7e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXG53903.1 - 4.4e-14 52.0 0.0 1e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXG53903.1 - 3.8e-07 30.2 0.0 1e-06 28.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXG53903.1 - 4.2e-07 30.2 0.0 8.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXG53903.1 - 3.3e-06 27.6 0.0 0.00016 22.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KXG53903.1 - 6.3e-05 23.3 0.2 0.023 15.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain Prot_ATP_ID_OB PF16450.5 KXG53903.1 - 8.4e-05 22.4 2.8 0.0002 21.3 2.8 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_18 PF13238.6 KXG53903.1 - 0.00052 20.6 0.0 0.03 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KXG53903.1 - 0.00058 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KXG53903.1 - 0.0058 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KXG53903.1 - 0.0061 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain ATPase PF06745.13 KXG53903.1 - 0.0069 15.8 0.0 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 KaiC IstB_IS21 PF01695.17 KXG53903.1 - 0.0072 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KXG53903.1 - 0.013 14.9 0.1 0.03 13.7 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXG53903.1 - 0.018 14.9 0.0 0.051 13.4 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXG53903.1 - 0.023 14.4 0.0 0.046 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KXG53903.1 - 0.03 13.8 0.0 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 KXG53903.1 - 0.036 14.1 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KXG53903.1 - 0.043 13.0 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) HR1 PF02185.16 KXG53903.1 - 0.043 13.9 0.5 0.11 12.7 0.5 1.6 1 0 0 1 1 1 0 Hr1 repeat Sigma54_activat PF00158.26 KXG53903.1 - 0.052 13.3 0.0 0.22 11.2 0.0 2.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_7 PF12775.7 KXG53903.1 - 0.06 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KXG53903.1 - 0.061 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Prot_ATP_OB_N PF17758.1 KXG53903.1 - 0.075 12.7 0.4 0.26 11.0 0.1 2.1 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain AAA_25 PF13481.6 KXG53903.1 - 0.081 12.5 0.1 0.22 11.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain DUF2072 PF09845.9 KXG53903.1 - 0.082 13.2 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_14 PF13173.6 KXG53903.1 - 0.084 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXG53903.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXG53903.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Na_Ca_ex PF01699.24 KXG53904.1 - 1.1e-21 77.4 33.5 4.5e-16 59.2 12.6 3.5 4 1 0 4 4 4 2 Sodium/calcium exchanger protein FGGY_C PF02782.16 KXG53905.1 - 1.3e-51 175.2 0.5 1.8e-51 174.7 0.5 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXG53905.1 - 1.3e-22 80.6 0.0 2e-20 73.4 0.0 2.4 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KXG53905.1 - 0.041 13.4 0.1 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DEDD_Tnp_IS110 PF01548.17 KXG53905.1 - 0.31 10.9 0.8 1 9.2 0.2 2.0 2 0 0 2 2 2 0 Transposase F-box PF00646.33 KXG53906.1 - 0.027 14.4 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 F-box domain F-box-like_2 PF13013.6 KXG53906.1 - 0.051 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.7 KXG53906.1 - 0.13 12.2 0.3 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 F-box-like BUD22 PF09073.10 KXG53906.1 - 3.5 6.9 5.0 5 6.3 5.0 1.1 1 0 0 1 1 1 0 BUD22 Y_phosphatase PF00102.27 KXG53907.1 - 9.2e-60 202.1 0.0 7e-59 199.2 0.0 2.2 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 KXG53907.1 - 1.4e-07 32.0 0.0 5.2e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 KXG53907.1 - 0.0045 16.8 0.1 0.0094 15.8 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KXG53907.1 - 0.01 15.8 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family COX16 PF14138.6 KXG53908.1 - 2.7e-30 104.7 0.1 3.5e-30 104.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Arc_PepC_II PF06847.11 KXG53908.1 - 0.015 15.8 0.0 0.059 13.9 0.0 1.8 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Nic96 PF04097.14 KXG53909.1 - 1.4e-218 727.4 0.0 1.8e-218 727.0 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 KXG53909.1 - 0.023 15.5 44.1 0.07 14.0 30.8 2.7 2 0 0 2 2 2 0 Nucleoporin FG repeat region RibD_C PF01872.17 KXG53910.1 - 1e-30 107.1 0.0 1.5e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain RCC1 PF00415.18 KXG53911.1 - 6e-56 186.9 8.9 1.5e-10 41.5 0.3 7.9 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXG53911.1 - 3.6e-30 103.1 34.4 5e-07 29.4 1.8 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat NAD_binding_6 PF08030.12 KXG53911.1 - 0.048 13.8 2.9 0.23 11.6 2.1 2.1 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Dicty_REP PF05086.12 KXG53911.1 - 0.15 10.0 6.1 0.17 9.8 6.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Macoilin PF09726.9 KXG53911.1 - 1.2 7.6 13.1 1.6 7.2 13.1 1.1 1 0 0 1 1 1 0 Macoilin family Pkinase_fungal PF17667.1 KXG53911.1 - 2.2 7.0 6.0 3.2 6.4 6.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Apt1 PF10351.9 KXG53911.1 - 3.7 6.3 11.9 5.2 5.8 11.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 KXG53911.1 - 8.1 5.1 13.0 11 4.6 13.0 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 KXG53911.1 - 8.3 5.0 14.8 11 4.6 14.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SMYLE_N PF18615.1 KXG53911.1 - 10 5.6 10.9 15 5.0 10.9 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Swi3 PF07962.12 KXG53912.1 - 9.1e-35 118.5 0.6 1.3e-34 118.0 0.6 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 NADH-u_ox-rdase PF10785.9 KXG53913.1 - 9.6e-30 103.1 0.1 1.5e-29 102.5 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KXG53913.1 - 3.1e-25 88.0 0.2 4.1e-25 87.6 0.2 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit PI3_PI4_kinase PF00454.27 KXG53914.1 - 4.5e-52 177.3 0.0 9e-52 176.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 KXG53914.1 - 4.7e-37 126.0 1.6 1.5e-36 124.3 0.5 2.6 2 0 0 2 2 2 1 UME (NUC010) domain FAT PF02259.23 KXG53914.1 - 1.7e-30 106.4 4.7 2.8e-28 99.2 1.9 3.4 2 1 1 3 3 3 2 FAT domain FATC PF02260.20 KXG53914.1 - 8.8e-13 47.8 0.0 2e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 FATC domain TPR_7 PF13176.6 KXG53914.1 - 0.0065 16.4 1.7 14 6.0 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXG53914.1 - 0.014 15.8 0.2 0.93 10.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXG53914.1 - 0.055 14.3 1.4 72 4.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3385 PF11865.8 KXG53914.1 - 0.12 12.3 0.0 1.2 9.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) ANAPC5 PF12862.7 KXG53914.1 - 0.15 12.2 0.4 6.7 6.8 0.1 3.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 AAA PF00004.29 KXG53915.1 - 2.7e-64 215.5 0.0 1e-40 139.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXG53915.1 - 3.2e-19 68.5 0.7 1e-12 47.6 0.2 2.9 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KXG53915.1 - 3.6e-12 47.0 1.5 0.01 16.2 0.1 4.6 2 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 KXG53915.1 - 4.1e-08 33.3 0.4 0.01 15.8 0.1 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 KXG53915.1 - 1.5e-07 31.5 0.0 3.3e-05 23.8 0.0 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein RuvB_N PF05496.12 KXG53915.1 - 5.9e-06 26.1 0.0 0.015 15.0 0.0 4.0 5 0 0 5 5 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KXG53915.1 - 1.5e-05 24.7 0.6 0.13 11.8 0.0 4.0 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KXG53915.1 - 1.6e-05 25.0 0.0 0.056 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 KXG53915.1 - 3.7e-05 23.7 0.4 0.0027 17.7 0.0 3.0 2 1 1 3 3 3 1 Rad17 P-loop domain DUF815 PF05673.13 KXG53915.1 - 8.1e-05 21.9 0.0 0.35 10.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_2 PF07724.14 KXG53915.1 - 0.00015 21.9 0.0 0.06 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXG53915.1 - 0.00019 21.7 4.3 1.6 9.0 1.1 4.1 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 KXG53915.1 - 0.00033 20.0 0.1 0.13 11.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_28 PF13521.6 KXG53915.1 - 0.00046 20.5 0.2 1.5 9.1 0.1 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KXG53915.1 - 0.00049 19.9 0.0 0.057 13.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 KXG53915.1 - 0.00075 19.1 0.1 0.51 9.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 KXG53915.1 - 0.00087 19.6 0.1 2.3 8.7 0.0 3.0 3 0 0 3 3 2 2 RNA helicase ATPase_2 PF01637.18 KXG53915.1 - 0.0018 18.2 0.0 0.64 9.9 0.0 3.2 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 KXG53915.1 - 0.0056 16.1 0.2 0.32 10.3 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI CDC48_N PF02359.18 KXG53915.1 - 0.0058 16.8 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_24 PF13479.6 KXG53915.1 - 0.013 15.2 0.0 0.26 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXG53915.1 - 0.025 14.8 0.3 8.3 6.6 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA_11 PF13086.6 KXG53915.1 - 0.028 14.2 0.0 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KXG53915.1 - 0.031 14.4 0.0 0.42 10.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain RRM_1 PF00076.22 KXG53915.1 - 0.031 14.1 0.0 0.19 11.6 0.0 2.4 2 0 0 2 2 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_30 PF13604.6 KXG53915.1 - 0.034 13.9 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KXG53915.1 - 0.074 13.1 0.0 20 5.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KXG53915.1 - 0.078 12.9 3.2 3.5 7.5 0.5 3.4 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.6 KXG53915.1 - 0.078 13.5 0.0 2.2 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXG53915.1 - 0.12 12.9 0.2 1.8 9.0 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Ras PF00071.22 KXG53916.1 - 2.7e-65 218.9 0.0 3.2e-65 218.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXG53916.1 - 4.7e-34 117.2 0.0 7.2e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG53916.1 - 6.5e-14 51.8 0.0 8.4e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXG53916.1 - 4.1e-06 26.5 0.0 8.8e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXG53916.1 - 0.00013 21.4 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KXG53916.1 - 0.00076 19.4 0.2 0.78 9.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXG53916.1 - 0.004 17.2 0.0 0.008 16.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXG53916.1 - 0.022 14.3 0.0 0.11 12.0 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B NCA2 PF08637.10 KXG53917.1 - 9.6e-102 340.0 1.2 3.2e-101 338.3 0.3 1.9 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.13 KXG53918.1 - 3.3e-25 89.0 16.9 3.3e-25 89.0 16.9 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily UCH PF00443.29 KXG53919.1 - 1.7e-39 135.9 0.0 2.4e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KXG53919.1 - 2.1e-25 88.3 1.4 1e-23 82.8 0.1 2.7 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 KXG53919.1 - 1.3e-22 79.8 19.0 1.6e-18 66.8 2.5 3.5 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 KXG53919.1 - 5.7e-20 70.8 0.4 1.1e-10 41.2 0.0 2.9 3 0 0 3 3 3 2 UBA/TS-N domain UCH_1 PF13423.6 KXG53919.1 - 1.6e-17 64.1 0.2 3.9e-16 59.5 0.1 2.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 KXG53919.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain DUF1815 PF08844.10 KXG53919.1 - 0.37 10.8 1.7 4.2 7.4 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1815) Rep_fac-A_C PF08646.10 KXG53920.1 - 6.3e-55 184.9 2.5 9e-53 177.9 0.2 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KXG53920.1 - 6.3e-37 125.4 0.5 3.1e-36 123.2 0.4 2.1 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 KXG53920.1 - 1.1e-22 79.9 0.4 5.7e-22 77.6 0.0 2.1 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KXG53920.1 - 1.2e-12 47.6 0.0 1.3e-08 34.7 0.0 3.6 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KXG53920.1 - 0.00029 20.6 0.2 0.007 16.1 0.0 2.7 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 DUF5521 PF17659.1 KXG53920.1 - 0.025 12.5 0.0 0.036 11.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) DEAD PF00270.29 KXG53921.1 - 1.7e-49 168.0 0.0 4.6e-49 166.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG53921.1 - 1.7e-32 112.0 0.1 2.1e-29 102.1 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KXG53921.1 - 6.1e-09 36.1 0.0 1.6e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KXG53921.1 - 0.0018 17.1 0.0 0.53 9.0 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 KXG53921.1 - 0.0029 16.9 0.1 0.0072 15.6 0.0 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 KXG53921.1 - 0.015 14.7 2.9 0.13 11.6 0.0 2.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Rft-1 PF04506.13 KXG53922.1 - 5.3e-139 464.3 17.5 6.3e-139 464.0 17.5 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 KXG53922.1 - 1.7e-07 30.9 11.2 1.7e-07 30.9 11.2 2.4 2 2 0 2 2 2 1 Polysaccharide biosynthesis protein OST3_OST6 PF04756.13 KXG53923.1 - 1.5e-105 352.8 0.0 1.7e-105 352.5 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KXG53923.1 - 0.023 14.7 0.0 0.056 13.4 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin HXXEE PF13787.6 KXG53923.1 - 1.6 9.5 8.3 0.14 13.0 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif FtsJ PF01728.19 KXG53924.1 - 1.6e-51 175.0 0.0 2.4e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KXG53924.1 - 0.0013 18.6 0.1 0.0052 16.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG53924.1 - 0.03 14.1 0.2 0.91 9.3 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.6 KXG53924.1 - 0.11 13.3 0.0 0.93 10.2 0.0 2.7 2 1 1 3 3 3 0 Methyltransferase domain ATG7_N PF16420.5 KXG53925.1 - 2.8e-112 375.3 0.0 3.6e-112 374.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KXG53925.1 - 1.2e-42 146.0 0.0 1.8e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KXG53925.1 - 0.045 13.8 0.0 0.31 11.1 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase His_biosynth PF00977.21 KXG53926.1 - 3.4e-45 154.3 0.2 8.2e-45 153.0 0.2 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KXG53926.1 - 6.9e-23 81.4 0.0 1.1e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KXG53926.1 - 2.2e-10 40.7 0.0 3.3e-09 36.8 0.0 2.2 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KXG53926.1 - 1e-08 35.0 0.0 4.8e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KXG53926.1 - 0.0044 16.8 0.1 0.037 13.8 0.1 2.2 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KXG53926.1 - 0.13 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family DWNN PF08783.11 KXG53927.1 - 2e-33 114.5 0.8 4.7e-33 113.3 0.1 2.0 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 KXG53927.1 - 3.6e-08 33.1 5.0 6.5e-08 32.3 5.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KXG53927.1 - 0.002 18.1 0.7 0.0041 17.1 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 KXG53927.1 - 0.0024 17.7 8.2 0.005 16.7 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KXG53927.1 - 0.22 11.3 3.4 0.61 10.0 3.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 KXG53927.1 - 0.32 11.4 6.6 0.69 10.3 6.6 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 KXG53927.1 - 0.4 10.5 6.0 0.97 9.3 6.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KXG53927.1 - 3.6 7.5 8.2 7.8 6.5 8.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXG53927.1 - 4 7.7 9.3 11 6.3 9.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KXG53927.1 - 7.9 6.5 11.6 0.48 10.4 5.4 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Yippee-Mis18 PF03226.14 KXG53928.1 - 4e-24 84.9 0.1 9.1e-24 83.7 0.1 1.6 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ODC_AZ PF02100.17 KXG53928.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme RIG-I_C-RD PF11648.8 KXG53928.1 - 0.067 13.4 1.1 0.61 10.3 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I SHNi-TPR PF10516.9 KXG53929.1 - 2.8e-13 49.1 0.4 8.8e-13 47.5 0.4 1.9 1 0 0 1 1 1 1 SHNi-TPR TPR_12 PF13424.6 KXG53929.1 - 0.00024 21.4 4.5 0.19 12.1 1.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXG53929.1 - 0.009 15.7 2.1 6.3 6.6 0.2 3.9 4 0 0 4 4 4 1 TPR repeat TPR_9 PF13371.6 KXG53929.1 - 0.12 12.6 1.5 4 7.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Snapin_Pallidin PF14712.6 KXG53929.1 - 0.96 9.9 7.4 3.4 8.2 2.6 3.3 3 0 0 3 3 3 0 Snapin/Pallidin DUF1664 PF07889.12 KXG53929.1 - 2.9 8.0 7.3 3.1 7.9 3.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CCDC-167 PF15188.6 KXG53929.1 - 6.8 7.1 12.9 0.13 12.6 4.6 2.5 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 TPR_2 PF07719.17 KXG53929.1 - 9.5 6.6 0.0 9.5 6.6 0.0 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DNA_pol_E_B PF04042.16 KXG53930.1 - 3.7e-47 160.4 0.0 5e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Med14 PF08638.11 KXG53931.1 - 1.8e-66 223.2 0.0 2.7e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 ATG22 PF11700.8 KXG53932.1 - 1e-168 561.9 11.8 1.2e-168 561.7 11.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KXG53932.1 - 2.7e-07 29.9 19.3 2.7e-07 29.9 19.3 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Thioredoxin PF00085.20 KXG53933.1 - 9.9e-64 211.8 3.0 1.1e-31 108.9 0.1 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KXG53933.1 - 2.4e-46 158.0 1.9 7.8e-35 120.4 0.4 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 KXG53933.1 - 1.4e-11 44.1 1.4 3e-11 43.0 0.8 1.8 2 0 0 2 2 2 1 Calsequestrin Redoxin PF08534.10 KXG53933.1 - 1.1e-08 34.9 3.4 0.071 12.8 0.1 3.4 3 0 0 3 3 3 3 Redoxin Thioredoxin_2 PF13098.6 KXG53933.1 - 1.3e-08 35.3 1.3 0.0076 16.7 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KXG53933.1 - 1.6e-08 34.6 0.1 0.011 15.8 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KXG53933.1 - 2.6e-08 33.8 1.6 0.00018 21.4 0.0 3.5 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_8 PF13905.6 KXG53933.1 - 1.8e-07 31.4 0.1 0.041 14.2 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like ERp29_N PF07912.13 KXG53933.1 - 5e-05 23.5 0.2 0.43 10.7 0.0 3.9 4 0 0 4 4 4 2 ERp29, N-terminal domain OST3_OST6 PF04756.13 KXG53933.1 - 0.00011 21.7 0.1 0.93 8.8 0.0 3.2 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 KXG53933.1 - 4.6 7.4 6.9 16 5.6 0.1 3.5 5 0 0 5 5 5 0 Thioredoxin UDG PF03167.19 KXG53934.1 - 5.2e-24 85.0 0.1 1e-23 84.0 0.1 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Fungal_trans PF04082.18 KXG53934.1 - 3.9e-10 39.2 0.0 7.9e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KXG53935.1 - 2.1e-31 109.0 1.1 3.8e-31 108.1 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_TACC PF12709.7 KXG53936.1 - 7.1e-13 48.8 18.8 2e-10 41.0 4.3 4.3 4 0 0 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins Filament PF00038.21 KXG53936.1 - 0.032 13.8 34.3 0.76 9.3 13.4 3.1 1 1 1 2 2 2 0 Intermediate filament protein Tropomyosin_1 PF12718.7 KXG53936.1 - 0.09 12.9 40.2 0.033 14.3 23.0 3.6 2 1 1 3 3 3 0 Tropomyosin like GAS PF13851.6 KXG53936.1 - 0.63 9.4 32.7 1.7 8.0 12.6 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding QueH PF02677.14 KXG53936.1 - 1.1 9.3 4.5 1.6 8.8 3.8 1.5 1 1 0 1 1 1 0 Epoxyqueuosine reductase QueH Fez1 PF06818.15 KXG53936.1 - 1.3 9.4 39.0 4.4 7.7 20.2 2.8 1 1 1 2 2 2 0 Fez1 DUF4407 PF14362.6 KXG53936.1 - 1.4 8.2 31.3 0.34 10.2 10.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) MFS_1 PF07690.16 KXG53937.1 - 4.7e-31 108.0 19.6 4.7e-31 108.0 19.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG53937.1 - 9.4e-09 34.6 2.9 9.4e-09 34.6 2.9 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter LacY_symp PF01306.19 KXG53937.1 - 0.00018 20.5 10.9 0.0032 16.3 5.3 2.2 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_3 PF05977.13 KXG53937.1 - 0.00098 17.6 4.4 0.053 11.9 3.1 2.3 1 1 1 2 2 2 2 Transmembrane secretion effector MFS_1_like PF12832.7 KXG53937.1 - 0.0041 16.0 3.4 0.0041 16.0 3.4 2.3 2 0 0 2 2 2 1 MFS_1 like family Peptidase_S49_N PF08496.10 KXG53938.1 - 5.3 7.1 8.7 4.3 7.4 5.1 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DbpA PF03880.15 KXG53939.1 - 0.0093 15.9 0.2 0.029 14.4 0.1 1.9 2 0 0 2 2 2 1 DbpA RNA binding domain DUF4187 PF13821.6 KXG53941.1 - 5e-21 74.2 3.2 1.2e-20 73.0 3.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KXG53941.1 - 2.4e-07 30.5 0.5 1.2e-06 28.3 0.5 2.2 1 1 0 1 1 1 1 G-patch domain COesterase PF00135.28 KXG53942.1 - 5.4e-85 286.2 0.0 6.8e-85 285.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG53942.1 - 2.9e-07 30.5 0.2 1.1e-06 28.7 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXG53942.1 - 0.0029 17.1 0.2 0.0047 16.4 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF4022 PF13214.6 KXG53942.1 - 0.14 12.5 0.2 0.39 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4022) Nop14 PF04147.12 KXG53943.1 - 8.3e-293 973.9 33.0 9.8e-293 973.7 33.0 1.0 1 0 0 1 1 1 1 Nop14-like family HEAT_2 PF13646.6 KXG53944.1 - 0.00033 21.0 0.8 0.00096 19.5 0.7 1.9 2 0 0 2 2 2 1 HEAT repeats ORC3_N PF07034.11 KXG53945.1 - 2.7e-38 131.9 0.0 1.4e-36 126.3 0.0 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KXG53945.1 - 8.4e-24 84.2 0.1 6.2e-20 71.7 0.1 2.7 1 1 0 1 1 1 1 Origin recognition complex winged helix C-terminal MRP-S26 PF14943.6 KXG53945.1 - 0.14 12.0 0.3 0.38 10.6 0.3 1.6 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 PPR_2 PF13041.6 KXG53946.1 - 0.00033 20.8 0.3 6.6 7.0 0.1 4.6 5 0 0 5 5 5 2 PPR repeat family Ku_PK_bind PF08785.11 KXG53946.1 - 0.12 12.5 0.1 0.38 10.9 0.1 1.8 1 0 0 1 1 1 0 Ku C terminal domain like TPR_14 PF13428.6 KXG53946.1 - 0.3 12.0 3.3 0.81 10.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec66 PF09802.9 KXG53947.1 - 4.1e-83 277.4 0.5 5e-83 277.1 0.5 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 AAA PF00004.29 KXG53948.1 - 2.2e-48 164.0 0.0 9.7e-42 142.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXG53948.1 - 4e-10 39.3 0.1 1.4e-09 37.6 0.0 1.9 2 0 0 2 2 1 1 AAA+ lid domain IstB_IS21 PF01695.17 KXG53948.1 - 1.2e-07 31.6 0.0 1.2e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 KXG53948.1 - 9.5e-07 29.4 1.9 8.4e-05 23.0 0.0 4.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KXG53948.1 - 2.9e-06 27.5 0.0 1e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXG53948.1 - 6e-05 23.1 0.0 0.0018 18.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Bromodomain PF00439.25 KXG53948.1 - 0.00077 19.5 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 Bromodomain RNA_helicase PF00910.22 KXG53948.1 - 0.0026 18.1 0.0 0.0079 16.6 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Sigma54_activ_2 PF14532.6 KXG53948.1 - 0.0028 17.8 0.0 0.7 10.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 KXG53948.1 - 0.003 17.8 0.1 0.069 13.4 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXG53948.1 - 0.003 17.3 0.0 0.0089 15.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KXG53948.1 - 0.012 15.7 0.0 0.11 12.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXG53948.1 - 0.015 14.7 0.1 0.17 11.2 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KXG53948.1 - 0.016 15.0 0.0 0.075 12.8 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KXG53948.1 - 0.018 14.6 0.0 0.053 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXG53948.1 - 0.02 14.9 0.0 0.067 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KXG53948.1 - 0.021 14.1 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 KXG53948.1 - 0.029 14.9 0.0 0.12 12.9 0.0 2.2 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXG53948.1 - 0.046 13.4 0.0 1.1 8.9 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KXG53948.1 - 0.059 12.5 0.0 0.25 10.4 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 KXG53948.1 - 0.065 13.1 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KXG53948.1 - 0.065 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 KXG53948.1 - 0.092 12.7 0.0 0.47 10.4 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KXG53948.1 - 0.12 12.9 0.0 0.45 11.0 0.0 2.0 1 0 0 1 1 1 0 ABC transporter Torsin PF06309.11 KXG53948.1 - 0.24 11.5 0.0 0.59 10.2 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA_11 PF13086.6 KXG53948.1 - 0.25 11.1 0.0 0.25 11.1 0.0 3.7 3 0 0 3 3 1 0 AAA domain zf-C2H2_jaz PF12171.8 KXG53950.1 - 0.066 13.5 0.5 0.066 13.5 0.5 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KXG53951.1 - 0.0052 17.4 1.1 0.0052 17.4 1.1 3.0 2 1 1 3 3 3 1 FOXP coiled-coil domain zf-C2H2 PF00096.26 KXG53951.1 - 0.0073 16.7 25.0 0.074 13.5 0.4 5.0 5 0 0 5 5 5 3 Zinc finger, C2H2 type DUF629 PF04780.12 KXG53951.1 - 0.23 9.9 5.4 0.35 9.3 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 KXG53951.1 - 1.1 10.3 21.1 3.4 8.8 0.1 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger GDA1_CD39 PF01150.17 KXG53952.1 - 1.5e-98 330.2 0.0 2.1e-98 329.8 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PIN_2 PF10130.9 KXG53952.1 - 0.17 12.1 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 PIN domain LRR_9 PF14580.6 KXG53953.1 - 3.1e-60 202.6 0.3 4.4e-60 202.2 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KXG53953.1 - 4.1e-08 32.8 3.6 4.1e-08 32.8 3.6 2.7 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 KXG53953.1 - 1e-06 29.0 7.8 0.0011 19.3 1.2 4.0 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) HTH_38 PF13936.6 KXG53953.1 - 0.028 14.2 0.4 0.075 12.8 0.4 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4349 PF14257.6 KXG53953.1 - 0.12 11.8 1.2 0.27 10.6 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) CBM_6 PF03422.15 KXG53954.1 - 0.077 13.3 0.2 0.27 11.6 0.1 2.0 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) PQQ_3 PF13570.6 KXG53955.1 - 0.0026 18.2 0.5 0.019 15.5 0.1 2.4 2 0 0 2 2 2 1 PQQ-like domain LEDGF PF11467.8 KXG53957.1 - 0.093 12.4 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) GMC_oxred_N PF00732.19 KXG53961.1 - 2e-63 214.5 0.0 2.5e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG53961.1 - 1.6e-34 119.5 0.0 2.6e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXG53961.1 - 2.6e-05 23.5 0.0 0.028 13.5 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXG53961.1 - 0.0002 20.7 0.2 0.0015 17.8 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG53961.1 - 0.00027 20.6 0.4 0.0032 17.1 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG53961.1 - 0.00033 20.8 0.1 0.0008 19.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXG53961.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KXG53961.1 - 0.0024 17.0 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXG53961.1 - 0.0029 16.9 0.1 0.26 10.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXG53961.1 - 0.0082 14.9 0.1 0.05 12.3 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KXG53961.1 - 0.012 15.6 1.7 0.053 13.5 0.1 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXG53961.1 - 0.067 12.0 0.3 0.11 11.3 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.18 KXG53961.1 - 0.13 12.5 0.2 0.3 11.3 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 KXG53961.1 - 0.14 12.7 0.1 0.42 11.2 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyridox_oxase_2 PF12766.7 KXG53962.1 - 9.9e-28 96.7 0.0 1.7e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SPICE PF15678.5 KXG53963.1 - 0.00068 19.1 1.7 0.00079 18.9 1.7 1.1 1 0 0 1 1 1 1 Centriole duplication and mitotic chromosome congression KfrA_N PF11740.8 KXG53963.1 - 0.0042 17.7 1.2 0.0042 17.7 1.2 2.3 2 0 0 2 2 2 1 Plasmid replication region DNA-binding N-term EspB_PE PF18625.1 KXG53963.1 - 0.014 15.8 0.4 0.014 15.8 0.4 2.8 2 1 2 4 4 4 0 ESX-1 secreted protein B PE domain Peroxin-3 PF04882.12 KXG53964.1 - 0.13 11.2 2.2 0.18 10.8 0.1 1.9 2 0 0 2 2 2 0 Peroxin-3 CCDC53 PF10152.9 KXG53964.1 - 0.51 10.7 11.2 0.4 11.1 3.3 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Trypan_PARP PF05887.11 KXG53964.1 - 9.9 6.1 12.6 0.76 9.8 4.8 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) MCM PF00493.23 KXG53965.1 - 2e-97 324.7 0.0 3.3e-97 324.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXG53965.1 - 3.6e-39 133.5 0.2 7.6e-39 132.4 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KXG53965.1 - 3.2e-32 111.0 0.2 1e-31 109.4 0.2 1.9 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KXG53965.1 - 5.5e-24 84.4 0.8 1.5e-23 83.1 0.3 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KXG53965.1 - 1.1e-16 61.2 1.5 2.7e-16 60.1 0.2 2.4 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXG53965.1 - 4.6e-05 22.9 0.0 0.00019 20.9 0.0 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXG53965.1 - 0.0036 17.3 0.0 0.01 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXG53965.1 - 0.0045 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXG53965.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RSN1_7TM PF02714.15 KXG53967.1 - 1.2e-91 306.8 19.3 1.2e-91 306.8 19.3 2.8 3 0 0 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXG53967.1 - 1.8e-43 148.0 6.7 1.8e-43 148.0 6.7 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXG53967.1 - 1.9e-35 122.7 0.6 3.1e-35 122.0 0.6 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KXG53967.1 - 9.7e-31 105.8 0.2 5e-30 103.5 0.1 2.1 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DUF3377 PF11857.8 KXG53967.1 - 0.059 13.3 0.0 0.059 13.3 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) SNF2_N PF00176.23 KXG53968.1 - 7.5e-15 54.5 7.0 4.3e-05 22.4 0.1 3.3 1 1 2 3 3 3 3 SNF2 family N-terminal domain Helicase_C PF00271.31 KXG53968.1 - 5.7e-11 42.7 0.0 1.3e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KXG53968.1 - 7.2e-05 22.6 1.7 0.00016 21.5 1.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXG53968.1 - 0.0051 16.6 3.3 0.011 15.5 3.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-CRD PF17979.1 KXG53968.1 - 0.0087 16.2 0.7 0.22 11.6 0.2 2.6 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions zf-C3HC4 PF00097.25 KXG53968.1 - 0.012 15.5 3.7 0.036 13.9 3.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXG53968.1 - 0.028 14.4 4.1 0.06 13.3 4.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXG53968.1 - 0.053 13.4 1.3 0.15 12.0 1.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ish1 PF10281.9 KXG53968.1 - 0.62 10.4 3.4 4.6 7.6 0.0 3.5 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein zf-RING_2 PF13639.6 KXG53968.1 - 0.72 10.2 4.7 1.7 9.0 4.7 1.7 1 0 0 1 1 1 0 Ring finger domain DZR PF12773.7 KXG53968.1 - 1.8 8.7 4.5 7.2 6.7 4.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_UBOX PF13445.6 KXG53968.1 - 2.1 8.5 4.7 5.6 7.1 4.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger p450 PF00067.22 KXG53971.1 - 5.7e-59 200.1 0.0 7e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 COQ9 PF08511.11 KXG53971.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 COQ9 Pkinase PF00069.25 KXG53972.1 - 2.8e-08 33.5 0.0 1.2e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG53972.1 - 0.0035 16.7 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pro_CA PF00484.19 KXG53973.1 - 1.5e-45 155.3 0.1 2.6e-45 154.5 0.0 1.3 2 0 0 2 2 2 1 Carbonic anhydrase AA_permease_2 PF13520.6 KXG53974.1 - 1.1e-56 192.5 41.1 1.3e-56 192.3 41.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG53974.1 - 4.7e-30 104.6 35.9 6.1e-30 104.2 35.9 1.1 1 0 0 1 1 1 1 Amino acid permease ABA_GPCR PF12430.8 KXG53974.1 - 0.28 10.9 5.6 0.69 9.6 0.4 2.5 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor TEX29 PF15839.5 KXG53974.1 - 1.2 9.8 0.0 1.2 9.8 0.0 2.7 3 0 0 3 3 3 0 Testis-expressed sequence 29 protein DUF2615 PF11027.8 KXG53974.1 - 4 7.6 5.3 7.4 6.8 0.3 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2615) DUF3951 PF13131.6 KXG53975.1 - 0.073 13.3 1.3 0.32 11.2 1.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) Npa1 PF11707.8 KXG53976.1 - 1.1e-96 324.2 0.3 3.6e-96 322.5 0.0 2.1 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KXG53976.1 - 1.4e-56 191.3 0.0 5.7e-56 189.3 0.0 2.2 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Acetyltransf_1 PF00583.25 KXG53977.1 - 1e-06 29.0 0.0 2.5e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXG53977.1 - 1.4e-05 25.1 0.0 3.6e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXG53977.1 - 1.7e-05 25.2 0.0 3.5e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG53977.1 - 0.0015 18.5 0.0 0.0054 16.7 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 KXG53977.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MREG PF15812.5 KXG53977.1 - 0.16 12.2 0.2 0.29 11.4 0.2 1.3 1 0 0 1 1 1 0 Melanoregulin Med31 PF05669.12 KXG53977.1 - 3.1 7.9 15.1 10 6.2 15.1 1.9 1 1 0 1 1 1 0 SOH1 HA2 PF04408.23 KXG53978.1 - 2e-24 85.9 0.1 1.3e-23 83.3 0.1 2.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXG53978.1 - 6e-21 74.6 0.0 1.3e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXG53978.1 - 1.6e-13 50.9 0.0 3.7e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KXG53978.1 - 1e-10 41.8 0.7 2.1e-10 40.8 0.7 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 KXG53978.1 - 0.00018 21.3 0.2 0.00052 19.8 0.2 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KXG53978.1 - 0.0005 19.2 0.0 0.001 18.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KXG53978.1 - 0.0011 19.2 0.0 0.003 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXG53978.1 - 0.003 17.3 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXG53978.1 - 0.027 14.8 0.1 0.057 13.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KXG53978.1 - 0.058 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 KXG53978.1 - 0.18 12.3 0.4 1.9 9.0 0.2 2.6 1 1 1 2 2 2 0 ABC transporter AAA_29 PF13555.6 KXG53978.1 - 0.19 11.5 0.0 0.56 10.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain CD99L2 PF12301.8 KXG53978.1 - 0.71 10.1 5.0 2.6 8.3 5.0 2.0 1 1 0 1 1 1 0 CD99 antigen like protein 2 SUV3_C PF12513.8 KXG53979.1 - 1.6e-17 63.2 0.2 3.5e-17 62.1 0.2 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KXG53979.1 - 6.7e-11 42.5 0.0 1.3e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TACC_C PF05010.14 KXG53979.1 - 0.12 12.1 0.3 0.25 11.1 0.3 1.4 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Suv3_C_1 PF18147.1 KXG53979.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 Sec1 PF00995.23 KXG53980.1 - 2.5e-114 383.6 0.0 3.2e-114 383.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family G-patch PF01585.23 KXG53981.1 - 6.4e-05 22.8 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 G-patch domain adh_short PF00106.25 KXG53982.1 - 2.4e-15 56.5 0.0 4.1e-12 46.0 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KXG53982.1 - 6.4e-07 29.5 0.1 1.4e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXG53982.1 - 9.6e-06 25.2 0.0 2.4e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KXG53982.1 - 0.00036 20.2 0.0 0.0014 18.3 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 KXG53982.1 - 0.0093 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KXG53982.1 - 0.058 12.5 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXG53982.1 - 0.17 10.9 0.0 0.17 10.9 0.0 2.0 3 0 0 3 3 3 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXG53983.1 - 6.5e-48 163.8 0.0 2.3e-47 162.0 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXG53983.1 - 3.9e-47 160.7 0.0 5.9e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXG53983.1 - 2.1e-16 59.8 0.0 3.4e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXG53983.1 - 2e-11 43.6 0.0 4.2e-10 39.3 0.1 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXG53983.1 - 2.8e-10 39.8 0.0 4.4e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KXG53983.1 - 2e-09 37.2 0.0 4.7e-09 36.0 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KXG53983.1 - 3e-06 27.3 0.0 5.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXG53983.1 - 2.2e-05 24.4 0.0 3.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 KXG53983.1 - 0.00028 20.5 0.0 0.00049 19.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 KXG53983.1 - 0.0015 17.8 0.1 0.013 14.7 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KXG53983.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family TSA PF03249.13 KXG53983.1 - 0.093 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Type specific antigen PAT1 PF09770.9 KXG53984.1 - 0 1179.7 0.0 0 1179.2 0.0 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.16 KXG53985.1 - 3.9e-128 427.3 11.2 5e-128 426.9 11.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.25 KXG53986.1 - 1.2e-28 99.0 0.6 1.7e-28 98.5 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 LIME1 PF15332.6 KXG53986.1 - 0.045 13.3 0.0 0.051 13.2 0.0 1.1 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 UMP1 PF05348.11 KXG53987.1 - 1.5e-36 125.2 0.0 2e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.6 KXG53988.1 - 3.1e-12 46.6 0.0 5.8e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KXG53988.1 - 0.0027 18.3 0.0 0.0065 17.0 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KXG53988.1 - 0.025 14.3 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family GHMP_kinases_N PF00288.26 KXG53989.1 - 2.8e-14 53.1 2.6 6.4e-14 51.9 2.6 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXG53989.1 - 1.2e-09 38.4 0.5 5e-09 36.4 0.0 2.3 2 2 1 3 3 3 1 GHMP kinases C terminal DUF4763 PF15960.5 KXG53989.1 - 0.005 16.2 0.6 0.0074 15.6 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) Methyltransf_11 PF08241.12 KXG53990.1 - 3.4e-21 75.7 0.0 7.6e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG53990.1 - 2.4e-20 73.0 0.0 7.8e-20 71.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG53990.1 - 4.4e-17 62.3 0.0 7.1e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG53990.1 - 9.2e-15 54.9 0.0 1.5e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG53990.1 - 2.4e-11 44.3 0.0 4.6e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXG53990.1 - 4.4e-11 42.6 0.0 6.1e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KXG53990.1 - 6.5e-11 42.0 0.0 4.6e-09 35.9 0.0 2.1 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KXG53990.1 - 5.1e-06 26.2 0.0 8.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KXG53990.1 - 4.2e-05 23.2 0.0 6.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KXG53990.1 - 0.0047 16.4 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KXG53990.1 - 0.0071 15.8 0.0 0.017 14.6 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 KXG53990.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 KXG53990.1 - 0.013 15.5 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXG53990.1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.16 KXG53990.1 - 0.018 13.6 0.0 0.025 13.1 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.11 KXG53990.1 - 0.019 13.9 0.1 0.3 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 KXG53990.1 - 0.034 14.0 0.0 0.37 10.6 0.0 2.1 1 1 0 1 1 1 0 Hypothetical methyltransferase TehB PF03848.14 KXG53990.1 - 0.043 13.2 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.20 KXG53990.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase AlaDh_PNT_C PF01262.21 KXG53990.1 - 0.15 11.3 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PPR_2 PF13041.6 KXG53993.1 - 7.7e-42 141.3 6.4 4.6e-09 36.3 0.0 12.8 11 4 5 16 16 16 7 PPR repeat family PPR_3 PF13812.6 KXG53993.1 - 4.4e-29 100.3 3.8 0.0013 18.7 0.0 11.1 8 3 5 13 13 13 8 Pentatricopeptide repeat domain PPR PF01535.20 KXG53993.1 - 3.6e-26 89.5 19.0 0.0011 19.0 0.0 13.2 14 2 0 14 14 14 6 PPR repeat PPR_long PF17177.4 KXG53993.1 - 2.8e-20 72.6 15.4 4.6e-09 36.0 0.0 7.2 6 1 0 7 7 7 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KXG53993.1 - 1.7e-18 66.0 4.0 1.7e-05 24.4 0.1 9.9 12 0 0 12 12 12 3 PPR repeat RPM2 PF08579.11 KXG53993.1 - 1.3e-06 28.8 0.0 0.00042 20.7 0.0 4.2 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_19 PF14559.6 KXG53993.1 - 0.00021 21.7 7.4 0.96 10.0 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXG53993.1 - 0.009 16.8 9.4 28 5.9 0.0 8.6 10 1 1 11 11 11 0 Tetratricopeptide repeat CHAD PF05235.14 KXG53993.1 - 0.024 14.6 4.5 0.33 10.9 0.1 3.1 3 0 0 3 3 3 0 CHAD domain TPR_7 PF13176.6 KXG53993.1 - 0.88 9.7 3.2 6.8 7.0 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat PNP_phzG_C PF10590.9 KXG53994.1 - 8.9e-16 57.7 0.4 1.2e-14 54.1 0.1 2.5 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KXG53994.1 - 8.8e-07 29.0 0.0 0.0024 18.0 0.0 2.5 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase EamA PF00892.20 KXG53994.1 - 0.00034 20.8 12.9 0.0039 17.4 12.9 2.1 1 1 0 1 1 1 1 EamA-like transporter family FAD_binding_3 PF01494.19 KXG53995.1 - 4.4e-19 68.9 0.0 6.6e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXG53995.1 - 3.2e-07 30.5 0.1 7.4e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXG53995.1 - 3.9e-06 26.2 1.0 6.5e-06 25.5 0.7 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXG53995.1 - 5.4e-06 25.8 0.5 0.00014 21.2 0.6 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXG53995.1 - 4.5e-05 23.2 5.1 0.025 14.2 4.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXG53995.1 - 0.00016 21.2 0.8 0.00016 21.2 0.8 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXG53995.1 - 0.0006 19.2 1.0 0.00094 18.5 1.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXG53995.1 - 0.0011 17.8 0.7 0.002 16.9 0.7 1.4 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KXG53995.1 - 0.0011 18.1 0.8 0.0023 17.1 0.7 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXG53995.1 - 0.0012 18.0 0.3 0.84 8.6 0.7 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 KXG53995.1 - 0.0044 17.5 1.9 0.013 16.0 1.9 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXG53995.1 - 0.028 13.7 0.6 0.073 12.4 0.3 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KXG53995.1 - 0.051 12.8 0.7 0.1 11.8 0.7 1.5 1 0 0 1 1 1 0 Thi4 family FMO-like PF00743.19 KXG53995.1 - 0.15 10.5 0.7 0.25 9.7 0.7 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.14 KXG53995.1 - 0.36 9.6 0.9 0.71 8.6 0.6 1.5 1 1 0 2 2 2 0 Tryptophan halogenase F-box-like PF12937.7 KXG53996.1 - 0.0015 18.3 0.2 0.008 16.1 0.2 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXG53996.1 - 0.007 16.2 1.1 0.075 12.9 0.0 2.9 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 KXG53996.1 - 0.017 15.0 0.0 0.051 13.5 0.0 1.9 1 0 0 1 1 1 0 F-box Amidohydro_2 PF04909.14 KXG53997.1 - 7.5e-32 111.3 0.0 9.1e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Pkinase PF00069.25 KXG53999.1 - 3.5e-27 95.4 0.0 3.6e-26 92.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG53999.1 - 7.1e-06 25.5 0.0 0.0082 15.5 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase tRNA_m1G_MT PF01746.21 KXG54000.1 - 0.073 12.8 0.0 0.097 12.4 0.0 1.1 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase Zn_clus PF00172.18 KXG54001.1 - 1.9e-08 34.2 10.2 3.7e-08 33.3 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KXG54002.1 - 1.3e-27 96.5 0.0 1.7e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG54002.1 - 2.7e-20 72.9 0.0 3.6e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG54002.1 - 8.5e-08 32.3 0.1 1.8e-07 31.3 0.1 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXG54002.1 - 0.00055 19.9 0.0 0.001 19.0 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Sigma54_activ_2 PF14532.6 KXG54002.1 - 0.0022 18.1 0.0 0.0045 17.1 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain BUD22 PF09073.10 KXG54003.1 - 0.026 13.9 9.6 0.03 13.7 9.6 1.1 1 0 0 1 1 1 0 BUD22 SURF2 PF05477.11 KXG54003.1 - 3.3 7.3 6.9 5.3 6.7 6.9 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Usp PF00582.26 KXG54004.1 - 2.8e-22 79.8 1.1 8.8e-22 78.1 0.1 2.2 2 0 0 2 2 2 1 Universal stress protein family MIF4G PF02854.19 KXG54005.1 - 5.1e-51 173.3 0.0 7.8e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KXG54005.1 - 3.6e-19 68.7 0.5 3.6e-19 68.7 0.5 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 TB2_DP1_HVA22 PF03134.19 KXG54006.1 - 3.5e-24 84.5 5.6 5.6e-24 83.9 5.6 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TANGO2 PF05742.12 KXG54007.1 - 5.2e-46 157.8 0.0 5.9e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Cellulase PF00150.18 KXG54008.1 - 1e-54 185.9 0.5 1.5e-54 185.4 0.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KXG54008.1 - 3.1e-13 49.4 12.6 3.1e-13 49.4 12.6 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain FSA_C PF10479.9 KXG54008.1 - 0.59 8.2 11.2 0.86 7.6 11.2 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus p450 PF00067.22 KXG54009.1 - 8.7e-58 196.2 0.0 1.1e-57 195.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 bZIP_1 PF00170.21 KXG54010.1 - 0.0024 17.9 1.8 0.0051 16.9 1.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor Tropomyosin_1 PF12718.7 KXG54010.1 - 0.1 12.8 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Tropomyosin like FMN_dh PF01070.18 KXG54012.1 - 9.7e-122 406.3 0.0 1.2e-121 406.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXG54012.1 - 2.1e-08 33.6 0.0 4.1e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXG54012.1 - 3.6e-05 23.1 0.0 5.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KXG54012.1 - 0.0002 20.9 0.0 0.017 14.6 0.0 2.4 1 1 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 KXG54012.1 - 0.0026 17.2 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 KXG54012.1 - 0.0031 16.8 0.1 0.0045 16.3 0.1 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiG PF05690.14 KXG54012.1 - 0.0045 16.3 0.0 0.25 10.6 0.0 2.4 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Fungal_trans_2 PF11951.8 KXG54013.1 - 1.2e-50 172.5 3.3 1.5e-50 172.1 3.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHDPS PF00701.22 KXG54014.1 - 1.5e-60 204.3 0.0 1.7e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Aldedh PF00171.22 KXG54015.1 - 3.3e-181 602.8 0.1 3.7e-181 602.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DLH PF01738.18 KXG54016.1 - 3.6e-17 62.7 0.1 2.1e-16 60.1 0.1 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KXG54016.1 - 0.0048 16.2 0.0 0.014 14.7 0.0 1.7 1 1 1 2 2 2 1 Serine aminopeptidase, S33 DUF1168 PF06658.12 KXG54016.1 - 0.018 14.8 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) BAAT_C PF08840.11 KXG54016.1 - 0.033 14.1 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal BPL_N PF09825.9 KXG54017.1 - 1.2e-146 488.7 0.0 1.5e-146 488.4 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KXG54017.1 - 2.2e-25 89.1 0.0 3.8e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family CHCH PF06747.13 KXG54018.1 - 4.2e-07 29.9 8.4 6e-07 29.4 8.4 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KXG54018.1 - 0.0011 18.9 2.1 0.19 11.8 0.6 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KXG54018.1 - 0.0067 16.4 5.6 0.11 12.5 0.7 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 KXG54018.1 - 0.065 13.5 3.5 0.14 12.4 3.4 1.5 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX17 PF05051.13 KXG54018.1 - 0.11 12.8 3.7 0.16 12.3 3.7 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Mgm101p PF06420.12 KXG54019.1 - 1.3e-86 288.4 0.0 1.8e-86 288.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 MS_channel PF00924.18 KXG54020.1 - 2.1e-22 79.7 0.4 3.9e-22 78.8 0.4 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KXG54020.1 - 0.00039 19.8 0.4 0.0013 18.2 0.4 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXG54020.1 - 0.0024 17.7 0.5 0.0093 15.8 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KXG54020.1 - 0.0089 15.5 0.1 0.024 14.1 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXG54020.1 - 0.027 14.9 0.1 0.07 13.6 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair Peptidase_M23 PF01551.22 KXG54020.1 - 0.18 12.0 1.2 4.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Peptidase family M23 PhyH PF05721.13 KXG54021.1 - 6.9e-25 88.5 0.1 1e-24 88.0 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) NACHT PF05729.12 KXG54022.1 - 0.026 14.5 0.1 0.073 13.0 0.1 1.8 1 1 0 1 1 1 0 NACHT domain DUF4688 PF15752.5 KXG54022.1 - 0.15 11.2 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4688) zf-RING_2 PF13639.6 KXG54024.1 - 1e-13 51.4 5.7 1.5e-13 50.8 5.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXG54024.1 - 3.4e-10 39.5 3.2 5.6e-10 38.8 3.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXG54024.1 - 5.1e-09 35.8 6.3 7.8e-09 35.2 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXG54024.1 - 2.5e-08 33.7 4.2 3.8e-08 33.1 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXG54024.1 - 2.4e-07 30.9 8.0 8.8e-07 29.1 8.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXG54024.1 - 2.2e-05 24.3 2.5 3.4e-05 23.7 2.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXG54024.1 - 3.2e-05 23.7 1.8 4.9e-05 23.1 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXG54024.1 - 3.3e-05 23.8 2.2 3.3e-05 23.8 2.2 1.7 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXG54024.1 - 6e-05 22.8 7.1 0.00086 19.1 7.3 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXG54024.1 - 8.7e-05 22.5 2.2 0.00016 21.6 2.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KXG54024.1 - 0.0004 20.1 4.0 0.00072 19.3 4.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KXG54024.1 - 0.0026 17.9 3.9 0.0066 16.6 4.0 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KXG54024.1 - 0.021 15.1 1.8 0.035 14.4 1.8 1.4 1 0 0 1 1 1 0 RING-like domain KCNQC3-Ank-G_bd PF11956.8 KXG54024.1 - 0.025 14.8 0.1 0.062 13.6 0.1 1.6 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 Zn_ribbon_17 PF17120.5 KXG54024.1 - 0.11 12.2 1.9 0.18 11.4 1.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 KXG54024.1 - 0.2 11.6 2.9 0.21 11.6 0.9 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 KXG54024.1 - 0.32 11.2 6.0 2.1 8.6 6.0 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KXG54024.1 - 1.1 9.2 4.9 16 5.5 6.0 2.1 1 1 1 2 2 2 0 PHD-finger Aminotran_1_2 PF00155.21 KXG54025.1 - 2.4e-82 277.0 0.0 2.8e-82 276.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Syntaxin-18_N PF10496.9 KXG54026.1 - 6.6e-12 45.5 0.7 6.9e-11 42.3 0.1 2.6 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KXG54026.1 - 0.00017 21.5 0.1 0.00051 20.0 0.0 1.9 2 0 0 2 2 2 1 SNARE domain BLOC1_2 PF10046.9 KXG54026.1 - 0.064 13.6 2.2 0.29 11.4 1.4 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PhzC-PhzF PF02567.16 KXG54027.1 - 2.1e-13 50.4 0.0 2.9e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein HNH_2 PF13391.6 KXG54028.1 - 2.9e-13 49.7 0.0 5.6e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease PBAN PF05874.11 KXG54028.1 - 0.019 14.9 0.0 0.046 13.6 0.0 1.6 2 0 0 2 2 2 0 Pheromone biosynthesis activating neuropeptide (PBAN) TPR_1 PF00515.28 KXG54029.1 - 4.2e-13 48.5 3.2 4.1e-06 26.4 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXG54029.1 - 2.5e-11 42.8 4.0 0.00079 19.3 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXG54029.1 - 1.1e-08 35.3 0.1 1.1e-05 25.6 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXG54029.1 - 1.8e-08 33.9 0.4 0.00016 21.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXG54029.1 - 2.4e-05 24.1 0.2 0.00085 19.2 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat PB1 PF00564.24 KXG54029.1 - 4.4e-05 23.3 0.0 7.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 PB1 domain TPR_11 PF13414.6 KXG54029.1 - 6.8e-05 22.5 0.3 0.0011 18.6 0.1 2.6 1 1 1 2 2 2 1 TPR repeat TPR_6 PF13174.6 KXG54029.1 - 0.00021 21.7 0.0 3.1 8.6 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXG54029.1 - 0.00023 21.7 0.3 0.011 16.3 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXG54029.1 - 0.00032 20.8 0.1 0.78 9.9 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXG54029.1 - 0.39 10.6 1.9 3.2 7.8 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat NMO PF03060.15 KXG54030.1 - 1.1e-55 189.3 1.0 1.5e-55 188.9 1.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXG54030.1 - 8.8e-13 48.0 2.1 1.3e-12 47.4 2.1 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXG54030.1 - 4.9e-07 29.1 3.0 7.6e-07 28.5 3.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXG54030.1 - 4.4e-05 22.8 1.7 8e-05 21.9 1.7 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KXG54030.1 - 0.022 14.0 0.5 0.034 13.4 0.5 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NmrA PF05368.13 KXG54032.1 - 1.7e-19 70.3 0.0 2.5e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG54032.1 - 8.6e-19 68.1 0.0 1.8e-18 67.1 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXG54032.1 - 1e-06 29.0 1.1 3.6e-06 27.3 0.1 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXG54032.1 - 1.4e-06 28.4 0.1 4.7e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KXG54032.1 - 0.00018 21.7 0.3 0.011 16.0 0.0 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.21 KXG54032.1 - 0.00074 19.1 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KXG54032.1 - 0.0021 18.6 1.2 0.086 13.4 0.1 2.5 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KXG54032.1 - 0.033 13.5 0.8 0.033 13.5 0.8 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KXG54032.1 - 0.033 14.1 1.1 0.044 13.7 0.1 1.8 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ArabFuran-catal PF09206.11 KXG54033.1 - 4.7e-152 505.8 12.3 4.7e-152 505.8 12.3 1.4 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 KXG54033.1 - 2.7e-55 186.2 2.1 3.9e-55 185.7 2.1 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain ApoL PF05461.11 KXG54033.1 - 0.25 10.6 0.8 0.37 10.1 0.8 1.1 1 0 0 1 1 1 0 Apolipoprotein L HTH_AsnC-type PF13404.6 KXG54034.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain APH PF01636.23 KXG54035.1 - 6.9e-12 45.8 0.2 9.9e-12 45.3 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family FAD_binding_4 PF01565.23 KXG54037.1 - 6.2e-18 64.9 0.9 1.1e-17 64.0 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG54037.1 - 1.3e-05 25.2 0.0 3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like TyeA PF09059.10 KXG54037.1 - 0.034 14.3 0.0 0.078 13.1 0.0 1.6 1 0 0 1 1 1 0 TyeA polyprenyl_synt PF00348.17 KXG54038.1 - 6.1e-44 150.0 0.0 1e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 KXG54038.1 - 4.7e-11 42.5 0.0 4e-09 36.2 0.0 2.5 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain Pterin_bind PF00809.22 KXG54039.1 - 1.1e-80 270.9 0.0 1.3e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KXG54039.1 - 4.7e-23 81.8 0.1 7.8e-23 81.1 0.1 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) ThiP_synth PF10120.9 KXG54039.1 - 0.079 12.6 0.8 0.26 10.9 0.2 1.9 2 0 0 2 2 2 0 Thiamine-phosphate synthase ArfGap PF01412.18 KXG54040.1 - 1.8e-33 115.0 0.8 3.3e-33 114.3 0.8 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TIM21 PF08294.11 KXG54041.1 - 6.3e-40 136.4 0.0 7.9e-40 136.1 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KXG54041.1 - 7.2e-05 22.5 0.0 0.00018 21.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 MR_MLE_C PF13378.6 KXG54042.1 - 5.4e-59 199.4 0.0 7.9e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KXG54042.1 - 8.7e-07 29.2 0.0 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Peptidase_Prp PF04327.12 KXG54042.1 - 0.031 14.5 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 Cysteine protease Prp PWI PF01480.17 KXG54043.1 - 6.7e-16 58.4 0.5 1.5e-15 57.3 0.5 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 KXG54043.1 - 0.029 14.2 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUKH_6 PF14568.6 KXG54043.1 - 0.13 12.7 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall PGI PF00342.19 KXG54044.1 - 6.8e-237 786.8 1.2 8e-237 786.6 1.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Ribosomal_S21 PF01165.20 KXG54046.1 - 9.6e-10 38.0 0.3 1.9e-09 37.1 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 Rhodanese PF00581.20 KXG54047.1 - 9.6e-12 45.4 0.0 1.2e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain 3Beta_HSD PF01073.19 KXG54047.1 - 0.056 12.4 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_28 PF02636.17 KXG54048.1 - 1.3e-81 274.1 0.0 1.6e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.25 KXG54050.1 - 6.4e-64 215.9 0.0 8.4e-64 215.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG54050.1 - 1.7e-27 96.4 0.0 6.1e-27 94.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXG54050.1 - 0.0096 14.9 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXG54050.1 - 0.079 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KXG54050.1 - 0.19 11.0 0.0 0.97 8.7 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KXG54050.1 - 0.43 9.3 2.2 0.92 8.2 2.2 1.6 1 1 0 1 1 1 0 Fungal protein kinase HMA PF00403.26 KXG54051.1 - 2e-13 50.6 0.0 4.2e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 KXG54051.1 - 1.3e-09 38.3 0.0 1.8e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Transp_cyt_pur PF02133.15 KXG54053.1 - 3.4e-43 148.0 38.0 4.4e-43 147.7 38.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin adh_short PF00106.25 KXG54054.1 - 3.9e-23 81.9 0.0 7.5e-21 74.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXG54054.1 - 8.7e-15 54.9 0.0 2.5e-12 46.8 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG54054.1 - 5.8e-10 39.4 0.0 1.2e-09 38.4 0.0 1.4 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KXG54054.1 - 0.0041 16.3 0.0 0.0055 15.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein eIF3g PF12353.8 KXG54055.1 - 1.7e-44 151.2 3.5 2.5e-44 150.7 3.5 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KXG54055.1 - 1e-14 54.1 0.0 1.6e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 KXG54055.1 - 0.023 15.0 0.8 0.057 13.7 0.2 1.8 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Ribosomal_L27_C PF18471.1 KXG54055.1 - 0.2 11.1 0.8 0.32 10.4 0.8 1.3 1 0 0 1 1 1 0 Ribosomal L27 protein C-terminal domain NDT80_PhoG PF05224.12 KXG54056.1 - 1.2e-36 126.7 0.0 2.4e-36 125.7 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Pkinase PF00069.25 KXG54058.1 - 6.7e-18 65.0 0.0 8.2e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG54058.1 - 6.1e-06 25.7 0.0 9.8e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AMP-binding PF00501.28 KXG54059.1 - 5.1e-89 298.8 0.0 7.5e-89 298.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG54059.1 - 0.00025 22.0 0.1 0.0007 20.5 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CdhD PF03599.16 KXG54059.1 - 0.11 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit E3_binding PF02817.17 KXG54059.1 - 0.15 12.5 0.0 0.5 10.8 0.0 1.9 1 0 0 1 1 1 0 e3 binding domain Methyltransf_16 PF10294.9 KXG54060.1 - 1.9e-07 31.0 0.0 0.022 14.5 0.0 2.6 3 0 0 3 3 3 2 Lysine methyltransferase Spidroin_N PF16763.5 KXG54061.1 - 0.14 12.2 3.0 0.1 12.6 0.6 1.9 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term DUF1682 PF07946.14 KXG54062.1 - 7.8 5.6 7.4 12 5.0 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) HSP70 PF00012.20 KXG54063.1 - 2.5e-262 871.4 19.1 2.9e-262 871.2 19.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXG54063.1 - 2.6e-14 52.8 6.3 3.1e-13 49.3 2.8 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KXG54063.1 - 0.0026 17.5 0.1 0.0067 16.2 0.1 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain THUMP PF02926.17 KXG54063.1 - 0.15 12.2 1.6 4.9 7.2 1.5 2.6 2 0 0 2 2 2 0 THUMP domain FtsA PF14450.6 KXG54063.1 - 2.4 8.6 12.7 1.9 8.9 0.3 4.3 3 3 0 3 3 3 0 Cell division protein FtsA Tom22 PF04281.13 KXG54063.1 - 5.8 6.7 11.6 1.5 8.6 7.9 2.0 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 RRN3 PF05327.11 KXG54063.1 - 9.2 4.7 11.0 13 4.2 11.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2415 PF10313.9 KXG54064.1 - 4.1e-16 58.6 0.1 1.2e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) DSHCT PF08148.12 KXG54065.1 - 2.2e-52 177.0 0.4 6e-52 175.6 0.4 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KXG54065.1 - 3.3e-40 137.0 0.1 8.4e-40 135.7 0.1 1.7 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KXG54065.1 - 9.1e-25 88.1 0.0 1.7e-24 87.2 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KXG54065.1 - 1.4e-17 64.0 0.0 3.2e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG54065.1 - 7.1e-06 26.3 0.0 1.8e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG54065.1 - 5.5e-05 23.2 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Porin_OmpG_1_2 PF16946.5 KXG54065.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 OMPG-porin 1 family IBN_N PF03810.19 KXG54066.1 - 2.9e-16 59.1 0.1 1e-12 47.8 0.0 3.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 KXG54066.1 - 6.7e-10 38.3 0.0 1.3e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 KXG54066.1 - 0.0011 17.6 1.5 0.23 9.9 0.1 2.8 3 0 0 3 3 3 2 CAS/CSE protein, C-terminus Xpo1 PF08389.12 KXG54066.1 - 0.0013 18.8 0.7 0.036 14.1 0.0 3.2 3 0 0 3 3 3 1 Exportin 1-like protein RTP1_C1 PF10363.9 KXG54066.1 - 0.0038 17.4 0.6 0.23 11.6 0.1 3.1 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 KXG54066.1 - 0.047 13.4 0.0 2.8 7.7 0.0 3.6 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 KXG54066.1 - 0.051 14.0 0.3 6.5 7.2 0.0 3.5 3 0 0 3 3 3 0 HEAT repeats SDA1 PF05285.12 KXG54066.1 - 1.7 8.0 8.9 3.1 7.1 8.9 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KXG54066.1 - 3 7.1 7.3 5.3 6.3 7.3 1.3 1 0 0 1 1 1 0 BUD22 HEAT_EZ PF13513.6 KXG54066.1 - 6.1 7.5 7.0 26 5.5 0.7 4.7 4 3 0 4 4 4 0 HEAT-like repeat Nup35_RRM_2 PF14605.6 KXG54068.1 - 4e-08 33.1 0.0 7.4e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 KXG54068.1 - 6.3e-08 32.3 0.0 1.8e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXG54068.1 - 0.013 15.3 0.1 0.034 14.0 0.0 1.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF3391 PF11871.8 KXG54068.1 - 0.2 12.2 0.1 0.2 12.2 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) DUF2046 PF09755.9 KXG54069.1 - 0.0023 17.2 0.8 0.17 11.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) SlyX PF04102.12 KXG54069.1 - 0.042 14.5 5.5 3.3 8.4 0.1 2.4 2 0 0 2 2 2 0 SlyX bZIP_2 PF07716.15 KXG54069.1 - 0.076 13.1 7.9 0.098 12.8 0.8 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DegS PF05384.11 KXG54069.1 - 0.11 11.9 4.5 0.073 12.6 1.3 1.9 2 0 0 2 2 2 0 Sensor protein DegS FlaC_arch PF05377.11 KXG54069.1 - 0.15 12.5 1.8 0.28 11.6 0.1 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Pox_A_type_inc PF04508.12 KXG54069.1 - 0.27 11.1 4.5 0.64 10.0 4.5 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat ADIP PF11559.8 KXG54069.1 - 0.47 10.5 5.5 0.27 11.3 0.6 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Csm1_N PF18504.1 KXG54069.1 - 0.65 10.4 4.4 1.7 9.0 1.3 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain TPR_MLP1_2 PF07926.12 KXG54070.1 - 0.036 14.1 1.3 0.036 14.1 1.3 2.7 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein CPSase_L_D2 PF02786.17 KXG54071.1 - 5.7e-108 359.3 0.1 9.7e-85 283.4 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KXG54071.1 - 1.6e-41 141.5 0.1 4.6e-41 140.0 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Dala_Dala_lig_C PF07478.13 KXG54071.1 - 7e-20 71.4 0.7 3.8e-09 36.4 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXG54071.1 - 3.8e-18 65.6 0.1 9.4e-08 31.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KXG54071.1 - 2.5e-12 46.7 0.0 3.1e-05 23.7 0.0 3.3 4 1 0 4 4 4 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KXG54071.1 - 9.4e-05 22.0 0.1 0.035 13.6 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 KXG54071.1 - 0.0001 22.1 0.1 0.21 11.3 0.1 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SET PF00856.28 KXG54073.1 - 1.2e-14 55.1 0.0 3.2e-14 53.7 0.0 1.8 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 KXG54073.1 - 4.7e-08 33.0 9.5 4.7e-08 33.0 9.5 2.1 2 0 0 2 2 2 1 MYND finger AAA PF00004.29 KXG54075.1 - 3e-53 179.8 0.0 3.6e-43 147.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KXG54075.1 - 1.8e-29 102.0 0.7 3.8e-29 100.9 0.7 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KXG54075.1 - 1.2e-13 50.6 0.2 2.3e-07 30.5 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KXG54075.1 - 3.6e-07 30.7 6.4 0.027 14.8 0.1 4.5 3 2 1 5 5 5 2 AAA ATPase domain AAA_2 PF07724.14 KXG54075.1 - 1e-06 29.0 0.0 0.058 13.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KXG54075.1 - 2e-06 27.8 0.1 0.0044 17.0 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KXG54075.1 - 5.2e-06 26.5 0.7 0.023 14.6 0.0 3.5 3 0 0 3 3 3 2 NACHT domain RuvB_N PF05496.12 KXG54075.1 - 1e-05 25.3 0.0 0.0086 15.8 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXG54075.1 - 1.5e-05 25.3 0.5 0.65 10.3 0.0 3.5 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 KXG54075.1 - 2.5e-05 24.9 0.2 0.16 12.5 0.2 3.2 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KXG54075.1 - 6.9e-05 22.6 0.1 0.067 12.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 KXG54075.1 - 9.9e-05 22.4 0.1 0.97 9.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KXG54075.1 - 0.00044 19.6 0.0 0.17 11.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 KXG54075.1 - 0.0009 19.4 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain PEX-2N PF09263.10 KXG54075.1 - 0.002 18.4 0.5 1.8 8.9 0.0 3.1 3 1 0 3 3 2 1 Peroxisome biogenesis factor 1, N-terminal AAA_25 PF13481.6 KXG54075.1 - 0.0021 17.6 0.5 2.8 7.5 0.2 3.2 2 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KXG54075.1 - 0.0044 16.4 0.2 0.18 11.1 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KXG54075.1 - 0.0046 17.0 0.0 2.1 8.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXG54075.1 - 0.0047 17.2 0.0 1.9 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KXG54075.1 - 0.0051 16.1 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 KXG54075.1 - 0.017 15.2 0.0 0.49 10.5 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KXG54075.1 - 0.023 15.1 0.0 8.2 6.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 KXG54075.1 - 0.035 13.6 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 KXG54075.1 - 0.047 14.2 0.0 19 5.8 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.6 KXG54075.1 - 0.053 13.9 0.0 1.8 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KXG54075.1 - 0.077 12.7 0.0 3.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 KXG54075.1 - 0.093 12.1 0.1 6.5 6.0 0.0 2.3 2 0 0 2 2 2 0 KaiC Viral_helicase1 PF01443.18 KXG54075.1 - 0.098 12.4 0.0 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KXG54075.1 - 0.1 12.9 0.1 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KXG54075.1 - 0.12 12.3 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 NTPase cobW PF02492.19 KXG54075.1 - 0.33 10.5 1.2 8 6.0 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.23 KXG54076.1 - 1.3e-102 341.6 0.0 2.3e-102 340.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXG54076.1 - 6.8e-32 110.0 0.3 1.2e-31 109.2 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXG54076.1 - 3.4e-20 72.3 1.0 8.8e-20 70.9 1.0 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXG54076.1 - 6e-20 71.8 0.7 1.5e-19 70.5 0.7 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXG54076.1 - 2.2e-07 30.5 0.0 1.7e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXG54076.1 - 8.7e-07 29.0 0.0 2.1e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KXG54076.1 - 0.0014 18.4 0.0 0.005 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 KXG54076.1 - 0.018 14.9 0.0 0.059 13.2 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 KXG54076.1 - 0.069 13.8 0.9 0.26 11.9 0.2 2.4 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI C-terminal PLDc_3 PF13918.6 KXG54076.1 - 0.1 12.3 0.1 3.9 7.1 0.0 2.4 2 0 0 2 2 2 0 PLD-like domain Sigma54_activat PF00158.26 KXG54076.1 - 0.14 11.8 0.0 0.86 9.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain EGF_CA PF07645.15 KXG54077.1 - 2.8e-06 27.4 5.4 2.8e-06 27.4 5.4 2.0 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.7 KXG54077.1 - 6.6e-05 23.0 4.8 6.6e-05 23.0 4.8 2.0 3 0 0 3 3 3 1 EGF domain cEGF PF12662.7 KXG54077.1 - 0.0039 17.1 0.3 0.0039 17.1 0.3 2.4 3 0 0 3 3 3 1 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KXG54077.1 - 0.012 15.9 4.1 0.012 15.9 4.1 2.6 2 2 0 2 2 2 0 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KXG54077.1 - 0.058 14.0 6.3 0.12 13.1 2.6 2.7 1 1 1 2 2 2 0 Human growth factor-like EGF DUF5346 PF17281.2 KXG54077.1 - 1.1 9.3 8.5 2.2 8.3 8.5 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5346) Carb_kinase PF01256.17 KXG54078.1 - 1.8e-55 188.0 0.5 3.2e-54 184.0 0.5 2.0 1 1 0 1 1 1 1 Carbohydrate kinase SPT2 PF08243.11 KXG54079.1 - 8e-06 26.3 15.4 8e-06 26.3 15.4 2.1 2 1 0 2 2 2 1 SPT2 chromatin protein Ribosomal_60s PF00428.19 KXG54080.1 - 1e-25 90.1 9.1 1.2e-25 89.9 9.1 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S19 PF00203.21 KXG54081.1 - 5.6e-33 112.7 0.3 7.9e-33 112.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 AMP-binding PF00501.28 KXG54082.1 - 8.2e-95 317.9 0.0 9.6e-95 317.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG54082.1 - 6.9e-11 43.0 0.0 1.4e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro_28 PF00295.17 KXG54083.1 - 1e-118 396.1 19.2 1.4e-118 395.7 19.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NAD_binding_10 PF13460.6 KXG54083.1 - 1.6e-22 80.3 0.1 3.1e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXG54083.1 - 5.9e-07 29.2 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXG54083.1 - 0.032 13.3 0.1 0.083 12.0 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain GFO_IDH_MocA PF01408.22 KXG54085.1 - 5.1e-24 85.4 0.2 1e-23 84.5 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXG54085.1 - 1.8e-06 28.0 0.0 3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.15 KXG54085.1 - 0.032 14.4 0.0 0.1 12.7 0.0 1.9 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KRE1 PF17056.5 KXG54085.1 - 0.04 13.6 0.0 0.38 10.5 0.0 2.1 2 0 0 2 2 2 0 Killer toxin-resistance protein 1 MIOX PF05153.15 KXG54086.1 - 1.4e-124 414.6 2.1 1.9e-124 414.2 2.1 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 KXG54086.1 - 0.021 15.1 2.5 0.51 10.6 0.0 3.2 2 2 1 3 3 3 0 HD domain Cytochrom_C_2 PF01322.20 KXG54086.1 - 0.034 15.0 2.4 0.064 14.2 2.4 1.5 1 0 0 1 1 1 0 Cytochrome C' NRIP1_repr_1 PF15687.5 KXG54086.1 - 0.13 11.9 2.4 0.19 11.3 2.4 1.2 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 1 Aldo_ket_red PF00248.21 KXG54087.1 - 3.1e-45 154.6 0.0 4.3e-43 147.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 KXG54088.1 - 6.2e-18 64.8 55.3 1.3e-17 63.8 48.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily AC_N PF16214.5 KXG54088.1 - 0.23 10.5 0.8 0.49 9.5 0.8 1.4 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region ECH_1 PF00378.20 KXG54089.1 - 1.1e-51 175.5 0.0 1.4e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXG54089.1 - 1.1e-24 87.5 0.1 4.2e-21 75.8 0.1 2.5 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DoxD PF04173.13 KXG54089.1 - 0.059 13.3 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 TQO small subunit DoxD Acetyltransf_8 PF13523.6 KXG54090.1 - 5e-38 130.0 0.2 7.8e-38 129.4 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ABC_membrane PF00664.23 KXG54091.1 - 1.5e-89 300.3 26.9 3.9e-52 177.6 6.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXG54091.1 - 1.2e-62 210.5 0.0 1.1e-30 106.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXG54091.1 - 3.2e-16 59.4 2.0 1e-05 25.1 0.0 4.4 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXG54091.1 - 1.2e-08 34.5 0.3 0.0024 17.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXG54091.1 - 1e-07 32.3 0.6 0.17 12.1 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KXG54091.1 - 3.5e-06 27.5 3.0 0.031 14.7 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXG54091.1 - 4.3e-06 26.7 0.1 0.062 13.2 0.0 3.5 2 1 1 3 3 3 2 RsgA GTPase AAA_30 PF13604.6 KXG54091.1 - 8.1e-06 25.7 2.8 0.07 12.8 0.0 4.0 3 1 0 3 3 3 2 AAA domain APS_kinase PF01583.20 KXG54091.1 - 2.2e-05 24.4 0.1 0.012 15.6 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase DUF87 PF01935.17 KXG54091.1 - 3.3e-05 24.1 0.4 0.032 14.3 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_23 PF13476.6 KXG54091.1 - 0.00039 21.0 2.0 0.71 10.3 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 KXG54091.1 - 0.00049 20.5 1.1 11 6.5 0.3 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KXG54091.1 - 0.00094 18.5 0.0 0.76 9.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.6 KXG54091.1 - 0.0018 18.8 0.0 2.9 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 KXG54091.1 - 0.0019 17.1 1.9 0.033 13.0 0.0 2.6 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 KXG54091.1 - 0.0025 17.4 0.9 1.2 8.7 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_21 PF13304.6 KXG54091.1 - 0.0028 17.5 0.2 0.24 11.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 KXG54091.1 - 0.0028 17.6 0.0 4.1 7.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXG54091.1 - 0.0046 17.1 0.3 4 7.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain DUF3987 PF13148.6 KXG54091.1 - 0.012 14.7 0.0 2.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_7 PF12775.7 KXG54091.1 - 0.02 14.4 0.0 8.7 5.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region KdpD PF02702.17 KXG54091.1 - 0.022 14.2 0.0 2 7.8 0.0 2.4 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain NB-ARC PF00931.22 KXG54091.1 - 0.024 13.8 0.4 3 7.0 0.0 2.7 3 0 0 3 3 2 0 NB-ARC domain SbcCD_C PF13558.6 KXG54091.1 - 0.026 14.8 0.2 10 6.4 0.0 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KXG54091.1 - 0.028 14.5 0.1 7.3 6.7 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DEAD PF00270.29 KXG54091.1 - 0.033 13.9 0.1 0.52 10.1 0.1 2.9 3 1 0 3 3 3 0 DEAD/DEAH box helicase AAA_24 PF13479.6 KXG54091.1 - 0.06 13.1 0.0 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Cad PF03596.13 KXG54091.1 - 0.079 12.8 4.2 0.3 10.9 0.7 2.8 2 0 0 2 2 2 0 Cadmium resistance transporter AAA_17 PF13207.6 KXG54091.1 - 0.14 12.6 0.0 34 4.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KXG54091.1 - 0.21 11.3 0.2 11 5.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF1749 PF08538.10 KXG54092.1 - 3e-100 335.2 0.0 3.7e-100 334.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.20 KXG54092.1 - 0.00012 21.8 0.3 0.00042 20.0 0.1 2.0 2 1 1 3 3 3 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KXG54092.1 - 0.0048 16.6 0.0 0.014 15.1 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.12 KXG54092.1 - 0.0058 16.2 0.0 0.017 14.6 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 KXG54092.1 - 0.018 14.3 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AMP-binding PF00501.28 KXG54093.1 - 4.4e-74 249.6 0.0 1.2e-68 231.7 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KXG54093.1 - 2.1e-71 241.0 0.0 4.3e-35 121.3 0.0 2.5 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KXG54093.1 - 2.6e-27 95.0 0.3 4.1e-12 46.3 0.0 3.3 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXG54093.1 - 0.0004 21.3 0.1 2.5 9.1 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain SH3_9 PF14604.6 KXG54095.1 - 5.8e-08 32.5 0.3 1.4e-07 31.3 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXG54095.1 - 1e-06 28.3 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXG54095.1 - 1.1e-06 28.2 0.2 2.2e-06 27.1 0.2 1.6 1 0 0 1 1 1 1 SH3 domain RPAP2_Rtr1 PF04181.13 KXG54096.1 - 6.2e-19 68.1 0.0 1.1e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family Ribosomal_S17e PF00833.18 KXG54097.1 - 8.6e-61 203.3 1.1 1.1e-60 203.0 1.1 1.1 1 0 0 1 1 1 1 Ribosomal S17 Mit_ribos_Mrp51 PF11709.8 KXG54098.1 - 3.4e-109 365.8 0.1 4e-109 365.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Epimerase PF01370.21 KXG54099.1 - 6.3e-19 68.4 0.0 8.3e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXG54099.1 - 5.8e-17 61.6 0.0 7.6e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXG54099.1 - 3.2e-09 36.4 0.0 1.7e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KXG54099.1 - 1.5e-08 34.5 0.0 2.4e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXG54099.1 - 2.7e-06 27.4 0.0 4.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXG54099.1 - 2.4e-05 23.6 0.0 3.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KXG54099.1 - 0.00049 19.6 0.0 0.00092 18.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 KXG54099.1 - 0.00076 19.1 0.1 0.01 15.4 0.1 2.2 2 1 0 2 2 2 1 NmrA-like family KR PF08659.10 KXG54099.1 - 0.0064 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXG54099.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 KXG54099.1 - 0.012 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Semialdhyde_dh PF01118.24 KXG54099.1 - 0.042 14.3 0.0 0.26 11.7 0.0 2.3 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain FAT PF02259.23 KXG54100.1 - 1e-133 445.8 0.2 1e-133 445.8 0.2 2.3 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KXG54100.1 - 5.2e-70 236.1 0.1 1e-69 235.1 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KXG54100.1 - 3.1e-65 219.0 5.9 7.6e-61 204.7 1.3 4.8 4 1 1 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KXG54100.1 - 2.5e-41 140.1 0.1 2.5e-41 140.1 0.1 4.0 4 0 0 4 4 3 1 FKBP12-rapamycin binding domain CWC25 PF12542.8 KXG54100.1 - 3.7e-20 72.7 0.1 3.7e-20 72.7 0.1 2.4 2 0 0 2 2 1 1 Pre-mRNA splicing factor FATC PF02260.20 KXG54100.1 - 1e-15 57.3 1.0 2.2e-15 56.1 1.0 1.6 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.6 KXG54100.1 - 1.4e-15 57.4 10.4 0.00081 19.8 0.0 10.8 11 2 0 11 11 11 2 HEAT-like repeat Cir_N PF10197.9 KXG54100.1 - 8.8e-15 54.6 8.1 8.8e-15 54.6 8.1 4.2 4 0 0 4 4 2 1 N-terminal domain of CBF1 interacting co-repressor CIR HEAT_2 PF13646.6 KXG54100.1 - 2.3e-12 47.1 10.3 0.0049 17.2 0.0 9.0 8 2 1 9 9 9 3 HEAT repeats HEAT PF02985.22 KXG54100.1 - 8.9e-10 38.0 21.0 0.0052 16.9 0.0 11.4 13 0 0 13 13 11 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KXG54100.1 - 0.00057 20.4 1.4 48 4.6 0.0 7.3 6 2 2 8 8 8 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KXG54100.1 - 0.0023 17.5 0.6 1.6 8.2 0.0 4.5 5 0 0 5 5 5 1 CLASP N terminal Tti2 PF10521.9 KXG54100.1 - 0.0024 17.5 1.3 4 6.9 0.0 4.8 3 1 1 5 5 5 1 Tti2 family MMS19_C PF12460.8 KXG54100.1 - 0.0084 15.3 7.4 0.16 11.1 0.1 4.0 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal UME PF08064.13 KXG54100.1 - 0.0098 15.8 6.6 8.8 6.3 0.0 6.7 6 1 1 7 7 7 1 UME (NUC010) domain TPR_14 PF13428.6 KXG54100.1 - 0.014 16.1 0.2 1.5 9.9 0.0 4.2 2 1 1 3 3 2 0 Tetratricopeptide repeat Fe-S_biosyn PF01521.20 KXG54101.1 - 2.2e-10 40.7 0.0 2.2e-09 37.5 0.0 2.1 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Aminotran_5 PF00266.19 KXG54102.1 - 1.5e-13 50.5 0.0 5.2e-13 48.7 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXG54102.1 - 0.014 14.7 0.1 0.023 14.0 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 KXG54102.1 - 0.014 14.1 0.2 0.029 13.1 0.2 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 KXG54102.1 - 0.022 13.3 0.0 0.045 12.3 0.0 1.4 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme MFS_1 PF07690.16 KXG54103.1 - 2.6e-44 151.6 15.8 2.6e-44 151.6 15.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG54103.1 - 1.2e-10 40.9 16.3 3.7e-10 39.2 7.1 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_5 PF05631.14 KXG54103.1 - 0.00082 18.4 2.6 0.00082 18.4 2.6 2.0 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 KXG54103.1 - 0.0026 16.7 3.5 0.0026 16.7 3.5 2.2 2 0 0 2 2 2 1 MFS_1 like family Osw5 PF17062.5 KXG54103.1 - 0.036 14.2 0.0 0.036 14.2 0.0 2.5 3 0 0 3 3 3 0 Outer spore wall 5 LRR19-TM PF15176.6 KXG54103.1 - 0.12 12.4 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain UPF0542 PF15086.6 KXG54103.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 OATP PF03137.20 KXG54103.1 - 1.5 7.0 6.6 3 6.0 5.9 1.9 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ca_hom_mod PF14798.6 KXG54103.1 - 8.5 5.4 6.6 0.57 9.2 0.7 1.9 2 0 0 2 2 2 0 Calcium homeostasis modulator MFS_3 PF05977.13 KXG54103.1 - 9.5 4.5 11.7 0.13 10.6 2.2 2.4 3 0 0 3 3 3 0 Transmembrane secretion effector DUF1077 PF06417.12 KXG54104.1 - 1e-33 115.9 2.8 1.4e-33 115.4 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) TMEM171 PF15471.6 KXG54104.1 - 0.33 9.9 2.2 0.41 9.6 2.2 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Rubella_Capsid PF05750.11 KXG54104.1 - 8.1 6.0 8.9 9.9 5.7 8.9 1.2 1 0 0 1 1 1 0 Rubella capsid protein Adaptin_N PF01602.20 KXG54105.1 - 4.7e-116 388.4 9.0 6e-116 388.1 9.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXG54105.1 - 1.3e-56 191.1 10.4 1.5e-55 187.7 0.6 3.7 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXG54105.1 - 1.3e-12 47.9 3.5 0.00035 20.9 0.0 4.9 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.22 KXG54105.1 - 1.1e-10 40.9 2.9 0.0031 17.6 0.0 5.9 6 0 0 6 6 6 3 HEAT repeat Atx10homo_assoc PF09759.9 KXG54105.1 - 3.9e-06 26.8 0.2 0.85 9.7 0.0 4.1 3 1 1 4 4 4 2 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 KXG54105.1 - 1.4e-05 25.5 1.3 15 6.2 0.0 6.4 7 0 0 7 7 7 1 HEAT-like repeat CLASP_N PF12348.8 KXG54105.1 - 0.0041 16.7 1.0 1.6 8.2 0.0 3.2 3 0 0 3 3 3 2 CLASP N terminal Arm PF00514.23 KXG54105.1 - 0.015 15.3 1.1 2.9 8.1 0.0 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 KXG54105.1 - 0.2 11.4 3.0 7.2 6.3 0.0 3.1 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) CBP_BcsO PF17037.5 KXG54105.1 - 0.33 11.1 3.5 0.61 10.2 3.5 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO Paf67 PF10255.9 KXG54106.1 - 2.3e-159 530.7 0.0 2.8e-159 530.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KXG54106.1 - 0.096 12.9 0.0 0.6 10.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KXG54107.1 - 4.1e-19 68.6 0.2 6.3e-19 68.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG54107.1 - 1.3e-05 25.2 10.4 2.5e-05 24.3 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0147 PF03685.13 KXG54107.1 - 0.008 16.2 0.0 0.027 14.5 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0147) COG5 PF10392.9 KXG54107.1 - 0.16 12.1 1.5 0.25 11.5 0.3 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Aminotran_4 PF01063.19 KXG54108.1 - 5.1e-25 88.6 0.0 7.2e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV AAR2 PF05282.11 KXG54109.1 - 5.8e-97 325.2 0.0 7e-97 325.0 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S11 PF00411.19 KXG54110.1 - 3.9e-46 156.0 1.0 5e-46 155.6 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KXG54110.1 - 0.097 12.9 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) PDH PF02153.17 KXG54111.1 - 8.4e-12 44.6 0.0 1.1e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 KXG54111.1 - 0.0027 17.9 0.8 0.008 16.4 0.6 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KXG54111.1 - 0.0043 16.7 0.0 0.0096 15.6 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KXG54111.1 - 0.013 14.9 0.2 0.021 14.2 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXG54111.1 - 0.023 15.3 0.1 0.058 14.0 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KXG54111.1 - 0.048 13.2 0.2 0.089 12.4 0.2 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ERAP1_C PF11838.8 KXG54111.1 - 0.052 13.1 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 ERAP1-like C-terminal domain 3HCDH_N PF02737.18 KXG54111.1 - 0.38 10.6 1.1 0.67 9.8 1.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RICTOR_N PF14664.6 KXG54112.1 - 9.5e-126 419.7 0.4 9.5e-126 419.7 0.4 1.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 KXG54112.1 - 7.7e-38 129.2 0.1 1.6e-35 121.8 0.0 3.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 KXG54112.1 - 4.1e-36 122.9 3.0 9e-34 115.4 0.3 4.2 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 KXG54112.1 - 6.9e-26 90.3 0.6 6e-25 87.3 0.1 2.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KXG54112.1 - 1.7e-14 53.7 7.2 3.6e-14 52.6 7.2 1.6 1 0 0 1 1 1 1 Hr1 repeat BST2 PF16716.5 KXG54112.1 - 0.14 12.7 1.9 0.36 11.4 1.9 1.7 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 HIF-1a_CTAD PF08778.10 KXG54112.1 - 0.16 11.6 0.0 8.7 6.1 0.0 2.5 2 0 0 2 2 2 0 HIF-1 alpha C terminal transactivation domain Abhydrolase_3 PF07859.13 KXG54113.1 - 9.9e-43 146.4 0.1 1.2e-42 146.1 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG54113.1 - 0.0058 15.9 0.0 0.36 10.1 0.1 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KXG54113.1 - 0.0086 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Say1_Mug180 PF10340.9 KXG54113.1 - 0.096 11.5 0.0 0.17 10.8 0.0 1.3 2 0 0 2 2 2 0 Steryl acetyl hydrolase Zn_clus PF00172.18 KXG54114.1 - 4.8e-07 29.8 10.1 8.7e-07 29.0 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXG54114.1 - 0.00011 21.2 0.1 0.00014 20.8 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_11 PF13414.6 KXG54114.1 - 0.1 12.3 0.1 2.6 7.8 0.0 2.5 2 0 0 2 2 2 0 TPR repeat LON_substr_bdg PF02190.16 KXG54115.1 - 3e-26 92.6 0.0 6.4e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Amidohydro_1 PF01979.20 KXG54115.1 - 3e-22 79.4 0.0 4.2e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family zf-C3HC4_2 PF13923.6 KXG54115.1 - 1.1e-11 44.4 10.6 1.1e-11 44.4 10.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Amidohydro_3 PF07969.11 KXG54115.1 - 5e-10 39.5 0.1 2.5e-05 23.9 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family zf-C3HC4_3 PF13920.6 KXG54115.1 - 3.4e-09 36.4 19.7 1e-08 34.9 7.1 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXG54115.1 - 3.7e-09 36.4 18.7 1.2e-06 28.4 7.7 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXG54115.1 - 1.7e-08 34.5 20.0 4.2e-07 30.0 6.1 3.0 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KXG54115.1 - 1.4e-07 31.5 26.4 2.9e-07 30.4 4.4 3.9 4 0 0 4 4 4 2 RING-type zinc-finger zf-RING_2 PF13639.6 KXG54115.1 - 1.4e-07 31.7 9.0 1.4e-07 31.7 9.0 3.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KXG54115.1 - 1.7e-07 31.0 21.3 5.7e-07 29.3 9.3 2.8 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXG54115.1 - 3.5e-06 26.8 6.8 3.5e-06 26.8 6.8 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 KXG54115.1 - 3.6e-05 23.9 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.7 KXG54115.1 - 0.00027 21.1 4.5 0.00086 19.5 4.5 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KXG54115.1 - 0.0064 16.6 6.7 0.0064 16.6 6.7 2.4 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KXG54115.1 - 0.18 11.6 13.4 0.013 15.3 6.3 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KXG54115.1 - 0.58 9.9 10.7 0.034 13.8 4.7 2.1 2 0 0 2 2 2 0 P-11 zinc finger zf-Nse PF11789.8 KXG54115.1 - 0.72 9.7 4.2 1.8 8.5 4.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 KXG54115.1 - 2.8 7.7 7.3 3 7.7 3.1 2.9 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_6 PF14835.6 KXG54115.1 - 3 7.8 13.1 3.9 7.4 3.5 2.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Rad9 PF04139.13 KXG54116.1 - 2e-51 174.9 2.2 2.6e-51 174.5 2.2 1.1 1 0 0 1 1 1 1 Rad9 DUF2218 PF09981.9 KXG54116.1 - 0.073 13.5 0.4 0.49 10.8 0.1 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) PCC_BT PF18140.1 KXG54116.1 - 0.087 13.2 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain RCC1 PF00415.18 KXG54117.1 - 1.8e-34 118.1 13.1 7.8e-09 36.0 0.0 7.2 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXG54117.1 - 3.6e-19 68.1 21.9 1.6e-07 30.9 0.2 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Sugar_tr PF00083.24 KXG54118.1 - 5.7e-26 91.4 20.0 6.8e-24 84.5 20.0 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG54118.1 - 2.5e-06 26.7 33.5 2.7e-05 23.3 6.0 2.8 1 1 1 3 3 3 3 Major Facilitator Superfamily SUR7 PF06687.12 KXG54119.1 - 7.7e-16 58.4 4.7 9.7e-16 58.0 4.7 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KXG54119.1 - 2.2 8.2 11.5 0.054 13.4 4.6 1.7 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Mannitol_dh_C PF08125.13 KXG54120.1 - 3.1e-41 141.5 0.0 5.2e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KXG54120.1 - 7.3e-19 68.4 0.9 1e-18 67.9 0.2 1.6 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 KXG54120.1 - 0.0056 16.6 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain B12-binding PF02310.19 KXG54120.1 - 0.037 14.0 0.1 11 6.1 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain Pyr_redox_2 PF07992.14 KXG54120.1 - 0.058 12.6 0.4 0.11 11.7 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TFIIIC_sub6 PF10419.9 KXG54120.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 TFIIIC subunit triple barrel domain ECH_1 PF00378.20 KXG54121.1 - 6.8e-55 186.1 0.0 9.7e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXG54121.1 - 2e-25 90.0 0.1 1.7e-24 87.0 0.1 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase DoxD PF04173.13 KXG54121.1 - 0.037 13.9 0.0 0.072 13.0 0.0 1.5 2 0 0 2 2 2 0 TQO small subunit DoxD CheD PF03975.13 KXG54121.1 - 0.048 13.8 0.2 0.092 12.9 0.2 1.4 1 0 0 1 1 1 0 CheD chemotactic sensory transduction Myb_DNA-binding PF00249.31 KXG54122.1 - 3.3e-10 40.0 0.0 8.4e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KXG54122.1 - 3.5e-10 39.5 4.2 5.8e-10 38.8 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 KXG54122.1 - 1.7e-08 34.7 0.1 5.1e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 SWIRM domain Phage_Mu_Gam PF07352.12 KXG54122.1 - 4.4 7.2 7.5 21 5.0 0.1 2.9 2 1 1 3 3 3 0 Bacteriophage Mu Gam like protein Pkinase PF00069.25 KXG54123.1 - 5.6e-70 235.7 0.0 7.7e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG54123.1 - 3.7e-32 111.6 0.0 5.1e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KXG54123.1 - 1.2e-09 38.8 1.7 1.6e-09 38.3 0.2 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KXG54123.1 - 2.6e-06 26.7 0.0 4.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXG54123.1 - 0.038 13.3 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Coatomer_WDAD PF04053.14 KXG54124.1 - 2e-169 564.4 0.0 1.2e-168 561.8 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KXG54124.1 - 3.1e-38 129.1 8.7 1.8e-06 28.5 0.0 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG54124.1 - 4.1e-07 30.2 0.0 2.8 8.3 0.0 6.0 3 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXG54124.1 - 0.00013 20.8 1.6 0.18 10.4 0.0 3.7 1 1 3 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KXG54124.1 - 0.031 14.3 0.0 9.5 6.3 0.0 3.9 1 1 3 4 4 4 0 Ciliary BBSome complex subunit 2, middle region ETC_C1_NDUFA5 PF04716.14 KXG54125.1 - 6.5e-27 93.1 2.7 4.2e-25 87.3 0.0 2.7 3 0 0 3 3 3 2 ETC complex I subunit conserved region Ku_PK_bind PF08785.11 KXG54125.1 - 0.016 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Ku C terminal domain like Thioredoxin PF00085.20 KXG54126.1 - 3.2e-37 126.6 0.0 3e-23 81.8 0.0 4.0 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KXG54126.1 - 1.9e-10 41.0 0.0 6.4e-05 22.9 0.0 4.3 4 1 1 5 5 5 3 Thioredoxin-like domain AhpC-TSA PF00578.21 KXG54126.1 - 0.00018 21.4 1.0 0.53 10.2 0.0 3.3 3 1 0 3 3 3 2 AhpC/TSA family HyaE PF07449.11 KXG54126.1 - 0.0016 18.4 0.0 0.78 9.7 0.0 2.7 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 KXG54126.1 - 0.0018 18.5 0.8 5 7.5 0.1 4.1 4 1 1 5 5 5 1 Thioredoxin-like OST3_OST6 PF04756.13 KXG54126.1 - 0.023 14.0 0.0 6.1 6.1 0.0 2.5 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 KXG54126.1 - 0.073 13.1 0.1 2.4 8.3 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin domain QCR10 PF09796.9 KXG54127.1 - 2.8e-23 81.8 0.0 3.9e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) AA_permease_2 PF13520.6 KXG54128.1 - 8.7e-67 225.8 46.1 1.1e-66 225.5 46.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXG54128.1 - 2.6e-16 59.3 38.3 3.9e-16 58.7 38.3 1.3 1 0 0 1 1 1 1 Amino acid permease zf-H2C2_2 PF13465.6 KXG54129.1 - 4.7e-06 26.8 12.1 1.5e-05 25.2 1.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 KXG54129.1 - 0.00016 21.9 4.3 0.00029 21.1 4.3 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KXG54129.1 - 0.00024 21.7 15.0 0.017 15.9 5.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXG54129.1 - 0.0018 18.5 4.8 0.077 13.3 1.2 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KXG54129.1 - 0.033 14.7 14.5 0.11 13.0 7.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 KXG54129.1 - 0.71 10.3 5.0 4.1 7.9 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type SelP_N PF04592.14 KXG54130.1 - 0.031 13.7 17.6 0.049 13.0 17.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Mating_C PF12737.7 KXG54130.1 - 0.052 12.8 11.1 0.069 12.4 11.1 1.2 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Presenilin PF01080.17 KXG54130.1 - 0.83 8.4 2.4 0.92 8.2 2.4 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 KXG54130.1 - 6.3 5.2 10.8 7.7 4.9 10.8 1.0 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 KXG54130.1 - 7.8 5.6 20.1 9.4 5.3 20.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Nucleo_P87 PF07267.11 KXG54130.1 - 8.4 5.1 5.3 9.8 4.9 5.3 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PAD_porph PF04371.15 KXG54131.1 - 2.9e-95 319.2 0.0 3.6e-95 318.9 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase MFS_1 PF07690.16 KXG54132.1 - 9.9e-42 143.1 50.8 3.8e-35 121.4 26.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0060 PF02694.15 KXG54132.1 - 0.32 11.3 6.8 1.9 8.7 0.0 3.7 3 1 1 4 4 4 0 Uncharacterised BCR, YnfA/UPF0060 family OATP PF03137.20 KXG54132.1 - 1 7.5 12.3 0.093 11.0 2.5 3.3 2 2 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family MtN3_slv PF03083.16 KXG54132.1 - 1.2 9.3 4.5 1.5 8.9 0.3 2.7 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange Uricase PF01014.18 KXG54133.1 - 8.1e-77 255.8 1.4 4.7e-41 140.1 0.6 2.0 2 0 0 2 2 2 2 Uricase SnoaL_2 PF12680.7 KXG54133.1 - 0.028 15.1 1.2 0.042 14.5 0.3 1.8 2 0 0 2 2 2 0 SnoaL-like domain Ribosomal_L13 PF00572.18 KXG54134.1 - 3e-42 143.8 0.0 4e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.19 KXG54135.1 - 3.1e-33 114.9 0.9 3.5e-33 114.7 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 PilJ PF13675.6 KXG54135.1 - 0.035 14.1 0.3 0.052 13.6 0.3 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DNA_pol_B PF00136.21 KXG54136.1 - 5.1e-118 394.7 1.6 7.3e-118 394.2 1.6 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KXG54136.1 - 1.7e-68 230.0 1.9 3.6e-68 229.0 1.9 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KXG54136.1 - 7.1e-44 150.3 0.0 1.7e-43 149.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KXG54136.1 - 1.7e-23 82.5 7.0 1.7e-23 82.5 7.0 2.7 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal Phos_pyr_kin PF08543.12 KXG54137.1 - 1.5e-82 276.7 0.7 2.1e-82 276.2 0.7 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KXG54137.1 - 3.8e-52 177.1 0.6 5.5e-52 176.6 0.6 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KXG54137.1 - 1.1e-07 31.5 0.4 1.7e-06 27.6 0.4 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 KXG54137.1 - 0.00012 21.7 0.9 0.00036 20.1 0.4 1.9 2 0 0 2 2 2 1 Carbohydrate kinase HK PF02110.15 KXG54137.1 - 0.00059 19.3 0.3 0.23 10.8 0.0 2.3 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family DEAD PF00270.29 KXG54138.1 - 5.2e-49 166.4 0.0 4.4e-48 163.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG54138.1 - 1.7e-30 105.6 0.0 5.9e-30 103.9 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG54138.1 - 0.0016 18.4 0.0 0.0051 16.8 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXG54138.1 - 0.007 15.6 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 KXG54138.1 - 0.0098 16.2 0.0 0.62 10.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain UTP25 PF06862.12 KXG54138.1 - 0.03 13.1 0.1 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF5335 PF17269.2 KXG54138.1 - 0.032 14.1 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) AAA_22 PF13401.6 KXG54138.1 - 0.21 11.9 0.4 29 4.9 0.0 3.3 4 0 0 4 4 4 0 AAA domain Lipase_GDSL PF00657.22 KXG54139.1 - 2.2e-08 34.3 0.1 2.8e-08 34.0 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KXG54139.1 - 0.00073 20.0 1.4 0.0089 16.4 1.4 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SprA-related PF12118.8 KXG54140.1 - 0.036 13.2 1.9 0.057 12.6 1.9 1.2 1 0 0 1 1 1 0 SprA-related family DUF1387 PF07139.11 KXG54140.1 - 0.063 13.0 0.1 0.063 13.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) TFIIA PF03153.13 KXG54140.1 - 3.4 7.6 17.8 6.3 6.7 17.2 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPR_2 PF13041.6 KXG54141.1 - 2.1e-23 82.3 0.0 6.9e-17 61.4 0.0 3.4 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 KXG54141.1 - 7e-10 38.8 0.0 0.00013 22.0 0.0 3.1 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 KXG54141.1 - 0.00057 20.0 0.0 0.11 12.8 0.0 3.6 3 0 0 3 3 3 1 PPR repeat PPR_1 PF12854.7 KXG54141.1 - 0.021 14.5 2.0 2.8 7.7 0.0 3.7 4 0 0 4 4 4 0 PPR repeat Bac_luciferase PF00296.20 KXG54142.1 - 1.3e-61 208.7 0.1 1.8e-61 208.3 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Yip1 PF04893.17 KXG54143.1 - 5.1e-13 49.1 13.8 8.6e-13 48.4 13.8 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KXG54143.1 - 0.15 11.8 6.6 0.25 11.1 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF2070 PF09843.9 KXG54143.1 - 5.9 5.1 11.0 7 4.8 11.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DEAD PF00270.29 KXG54144.1 - 3.5e-25 88.8 0.0 6.4e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KXG54144.1 - 2.7e-18 66.5 0.1 6.8e-18 65.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Ran_BP1 PF00638.18 KXG54144.1 - 4.1e-16 59.4 0.4 1.1e-15 58.0 0.0 1.9 2 0 0 2 2 2 1 RanBP1 domain Helicase_C PF00271.31 KXG54144.1 - 2e-12 47.4 0.1 4.7e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.11 KXG54144.1 - 6.5e-08 33.1 0.1 1.3e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.15 KXG54144.1 - 0.0003 20.8 0.0 0.00054 20.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Fungal_trans_2 PF11951.8 KXG54145.1 - 7.7e-12 44.7 0.3 1.3e-11 44.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG54145.1 - 1.2e-07 31.7 10.1 2e-07 31.0 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GvpG PF05120.12 KXG54145.1 - 0.09 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Gas vesicle protein G SPX PF03105.19 KXG54145.1 - 5.5 6.8 12.4 8.7 6.1 12.4 1.2 1 0 0 1 1 1 0 SPX domain Formyl_trans_N PF00551.19 KXG54146.1 - 7.4e-40 136.6 0.1 9e-40 136.3 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase zf-RING_2 PF13639.6 KXG54147.1 - 1e-13 51.4 4.6 1.6e-13 50.8 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXG54147.1 - 2.9e-11 43.5 2.5 5.9e-11 42.5 2.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXG54147.1 - 1.3e-09 37.8 3.7 2e-09 37.1 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXG54147.1 - 7.7e-08 32.1 3.5 1.2e-07 31.5 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXG54147.1 - 1.2e-07 31.3 2.4 2.3e-07 30.5 2.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KXG54147.1 - 3.6e-06 26.9 0.4 7.1e-06 26.0 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXG54147.1 - 4.3e-06 26.3 2.4 7.2e-06 25.5 2.4 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KXG54147.1 - 2e-05 24.3 2.6 3.4e-05 23.6 2.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXG54147.1 - 3.8e-05 23.6 2.7 5.8e-05 23.0 2.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXG54147.1 - 0.00013 21.9 3.8 0.00026 20.9 3.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXG54147.1 - 0.00035 20.4 1.6 0.00056 19.7 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KXG54147.1 - 0.0045 17.1 5.0 0.0071 16.5 5.0 1.3 1 0 0 1 1 1 1 RING-variant domain zf-Nse PF11789.8 KXG54147.1 - 0.0087 15.9 1.0 0.017 14.9 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 KXG54147.1 - 0.021 15.1 1.1 0.04 14.2 1.1 1.4 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 KXG54147.1 - 0.035 14.3 2.5 0.063 13.5 2.5 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 KXG54147.1 - 0.099 12.7 1.8 0.19 11.8 1.8 1.5 1 0 0 1 1 1 0 Zinc-finger zf-C3HC4_5 PF17121.5 KXG54147.1 - 0.14 12.1 0.9 0.26 11.2 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_9 PF13901.6 KXG54147.1 - 0.17 11.9 0.2 0.26 11.3 0.2 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING_6 PF14835.6 KXG54147.1 - 0.2 11.6 1.5 0.39 10.6 1.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KXG54147.1 - 0.22 11.3 3.3 0.36 10.6 3.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KXG54147.1 - 2.4 8.1 4.1 4 7.4 4.1 1.4 1 0 0 1 1 1 0 PHD-finger RNA_pol_I_TF PF04090.12 KXG54148.1 - 1.1e-10 41.4 0.0 4.5e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor Nucleo_P87 PF07267.11 KXG54148.1 - 0.05 12.5 0.4 0.074 11.9 0.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ECM11 PF15463.6 KXG54149.1 - 1.4e-41 142.2 0.3 9.8e-41 139.5 0.0 2.6 2 0 0 2 2 2 1 Extracellular mutant protein 11 VPS9 PF02204.18 KXG54150.1 - 1.8e-27 95.6 0.0 3.2e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Lipase_3 PF01764.25 KXG54151.1 - 9.7e-07 28.7 0.0 3.3e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KXG54151.1 - 0.096 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KXG54151.1 - 0.18 11.5 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Catalase PF00199.19 KXG54152.1 - 1.3e-194 646.6 0.5 1.6e-194 646.4 0.5 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KXG54152.1 - 4.7e-11 42.7 0.0 1.3e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive SOXp PF12336.8 KXG54152.1 - 0.08 14.0 2.0 0.45 11.6 0.2 2.4 2 0 0 2 2 2 0 SOX transcription factor HCV_NS5a_C PF12941.7 KXG54153.1 - 0.11 12.3 0.4 0.17 11.7 0.4 1.2 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region Sugar_tr PF00083.24 KXG54154.1 - 9.5e-86 288.4 21.0 1.1e-85 288.2 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG54154.1 - 2.5e-17 62.8 27.3 7e-15 54.8 19.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG54154.1 - 0.0045 15.9 6.1 0.0045 15.9 6.1 2.3 2 0 0 2 2 2 1 MFS_1 like family ECH_1 PF00378.20 KXG54155.1 - 3.2e-79 265.8 0.0 5.2e-79 265.1 0.0 1.3 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXG54155.1 - 2.1e-36 126.1 0.3 3.3e-35 122.2 0.3 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Rer1 PF03248.13 KXG54156.1 - 1.2e-80 269.2 2.6 1.4e-80 269.0 2.6 1.0 1 0 0 1 1 1 1 Rer1 family DUF962 PF06127.11 KXG54156.1 - 0.18 11.9 4.0 2.1 8.5 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Ctr PF04145.15 KXG54157.1 - 7.3e-24 85.1 0.4 9.7e-24 84.7 0.4 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF3419 PF11899.8 KXG54158.1 - 1.1e-159 531.8 0.0 1.4e-159 531.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KXG54158.1 - 7.1e-12 45.5 0.0 1.7e-10 41.0 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG54158.1 - 5e-10 39.9 0.0 2.1e-08 34.7 0.0 3.3 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG54158.1 - 5.2e-10 39.3 0.0 1.5e-08 34.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG54158.1 - 1.1e-09 38.9 0.0 4.7e-09 36.9 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG54158.1 - 3.4e-09 37.2 0.0 9.8e-08 32.6 0.0 3.2 3 1 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXG54158.1 - 2.7e-06 26.9 0.0 1e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KXG54158.1 - 0.00068 19.5 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KXG54158.1 - 0.095 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 KXG54158.1 - 0.13 11.5 0.0 0.39 10.0 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase domain Paf1 PF03985.13 KXG54159.1 - 1.8e-56 192.0 0.0 2.7e-56 191.4 0.0 1.3 1 1 0 1 1 1 1 Paf1 Actin PF00022.19 KXG54160.1 - 1.1e-30 106.5 0.0 6.6e-18 64.5 0.0 2.4 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 KXG54160.1 - 7.2e-05 21.8 0.0 0.0056 15.5 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Actin_micro PF17003.5 KXG54160.1 - 0.00069 18.9 0.5 0.0019 17.5 0.2 1.7 2 0 0 2 2 2 1 Putative actin-like family FtsA PF14450.6 KXG54160.1 - 0.0032 17.9 0.0 0.013 16.0 0.0 1.9 2 1 0 2 2 2 1 Cell division protein FtsA DUF2114 PF09887.9 KXG54160.1 - 0.13 10.8 0.1 0.17 10.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Arf PF00025.21 KXG54161.1 - 3.2e-73 244.9 0.1 3.7e-73 244.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXG54161.1 - 5.8e-14 52.3 0.0 7.8e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXG54161.1 - 6.1e-12 45.3 0.0 7.8e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KXG54161.1 - 9.4e-11 41.6 0.0 1.1e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KXG54161.1 - 2.1e-09 37.0 0.1 3.1e-05 23.3 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KXG54161.1 - 3.3e-08 33.2 0.0 4.3e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXG54161.1 - 3.8e-06 27.0 0.0 6.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXG54161.1 - 0.00055 19.5 0.0 0.042 13.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KXG54161.1 - 0.0095 15.5 0.6 0.04 13.4 0.6 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B ADH_zinc_N PF00107.26 KXG54162.1 - 5.7e-26 91.0 0.3 9.4e-26 90.3 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG54162.1 - 2e-22 79.1 1.2 3.3e-22 78.4 1.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXG54162.1 - 2.9e-15 57.5 0.1 5.5e-15 56.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glucokinase PF02685.16 KXG54162.1 - 0.064 12.2 0.3 0.11 11.5 0.3 1.3 1 0 0 1 1 1 0 Glucokinase DHO_dh PF01180.21 KXG54164.1 - 1.1e-66 225.1 0.0 1.1e-65 221.7 0.0 2.0 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KXG54164.1 - 2e-05 23.8 0.1 0.004 16.2 0.4 2.6 2 1 0 2 2 2 2 FMN-dependent dehydrogenase PcrB PF01884.17 KXG54164.1 - 0.034 13.6 0.1 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 PcrB family TIM PF00121.18 KXG54165.1 - 1.7e-39 135.7 0.0 2.3e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.18 KXG54166.1 - 8.2e-44 149.0 0.0 9.2e-44 148.8 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase URO-D PF01208.17 KXG54166.1 - 0.057 12.5 0.0 0.11 11.6 0.0 1.4 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) Gly_rich_SFCGS PF14272.6 KXG54166.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycine-rich SFCGS U-box PF04564.15 KXG54167.1 - 6.5e-21 74.3 0.0 1.1e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 KXG54167.1 - 2.1e-08 33.7 5.4 0.00015 21.6 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXG54167.1 - 2e-07 30.5 6.0 8.8e-06 25.3 0.2 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXG54167.1 - 3e-05 24.5 6.6 0.022 15.5 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXG54167.1 - 4.5e-05 23.0 3.3 6e-05 22.6 0.0 2.8 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.6 KXG54167.1 - 6.3e-05 23.1 0.6 0.21 12.0 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXG54167.1 - 7.4e-05 23.2 6.5 0.0068 16.9 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXG54167.1 - 0.00041 20.9 11.2 0.059 14.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXG54167.1 - 0.0018 18.5 5.7 0.094 13.0 1.6 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG54167.1 - 0.0024 18.1 0.3 1 9.6 0.2 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 CHIP_TPR_N PF18391.1 KXG54167.1 - 0.0057 17.4 0.6 0.012 16.4 0.6 1.5 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain ACBP PF00887.19 KXG54168.1 - 8.3e-13 48.4 0.2 1.5e-12 47.5 0.2 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein MR_MLE_N PF02746.16 KXG54168.1 - 0.078 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Tyr-DNA_phospho PF06087.12 KXG54169.1 - 2.3e-166 553.9 0.0 2.9e-166 553.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Iso_dh PF00180.20 KXG54169.1 - 6.6e-85 285.3 0.0 1.1e-84 284.6 0.0 1.3 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PLDc_2 PF13091.6 KXG54169.1 - 0.061 13.2 0.0 0.99 9.3 0.0 2.3 2 0 0 2 2 2 0 PLD-like domain Fungal_trans PF04082.18 KXG54170.1 - 4.5e-17 61.9 0.1 9.5e-17 60.9 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.28 KXG54171.1 - 2.3e-90 303.9 0.0 5.8e-78 263.0 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG54171.1 - 7.9e-14 52.0 0.0 1.2e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold RRN3 PF05327.11 KXG54174.1 - 5.6e-176 586.4 0.0 7.4e-176 586.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 FliL PF03748.14 KXG54174.1 - 0.17 12.5 0.5 0.52 10.9 0.5 1.8 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL Gly_transf_sug PF04488.15 KXG54175.1 - 4.8e-07 30.3 0.0 1e-06 29.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KXG54175.1 - 0.0063 15.9 0.2 0.0098 15.3 0.2 1.4 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein DUF3454 PF11936.8 KXG54175.1 - 0.18 12.3 1.3 0.36 11.3 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3454) Glyco_transf_8 PF01501.20 KXG54176.1 - 5.9e-14 52.2 0.0 9.7e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 MIP PF00230.20 KXG54177.1 - 2.3e-43 148.5 10.4 2.9e-43 148.2 10.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein SKG6 PF08693.10 KXG54178.1 - 1.9e-06 27.2 0.0 1.9e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF2407_C PF13373.6 KXG54178.1 - 0.025 14.7 0.0 0.033 14.4 0.0 1.1 1 0 0 1 1 1 0 DUF2407 C-terminal domain SCHIP-1 PF10148.9 KXG54178.1 - 1 8.9 2.2 2.3 7.8 2.2 1.5 1 1 0 1 1 1 0 Schwannomin-interacting protein 1 PDE8 PF08629.10 KXG54178.1 - 1 9.4 5.9 2.2 8.3 5.9 1.5 1 0 0 1 1 1 0 PDE8 phosphodiesterase Abhydrolase_3 PF07859.13 KXG54179.1 - 5e-42 144.1 0.0 6.5e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXG54179.1 - 5.8e-06 25.5 0.3 2.4e-05 23.4 0.3 1.7 1 1 0 1 1 1 1 Carboxylesterase family DUF2974 PF11187.8 KXG54179.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 KXG54179.1 - 0.21 11.4 0.0 0.44 10.3 0.0 1.5 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase tRNA-synt_2 PF00152.20 KXG54180.1 - 5.5e-72 242.5 0.0 8.7e-72 241.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KXG54180.1 - 5.7e-17 61.7 0.0 8e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 KXG54180.1 - 0.00061 19.7 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXG54180.1 - 0.0051 16.3 0.2 2.3 7.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) MCM_N PF14551.6 KXG54180.1 - 0.025 15.2 0.1 0.069 13.7 0.1 1.8 1 0 0 1 1 1 0 MCM N-terminal domain Pga1 PF10333.9 KXG54181.1 - 0.00051 19.9 0.0 0.00097 19.0 0.0 1.4 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Tubulin PF00091.25 KXG54182.1 - 1.8e-66 224.1 0.0 2.7e-66 223.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXG54182.1 - 5.9e-50 168.7 0.0 1.1e-49 167.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KXG54182.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain EF-hand_4 PF12763.7 KXG54183.1 - 2.4e-37 127.0 0.0 2.7e-14 53.0 0.0 3.9 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KXG54183.1 - 2e-07 31.4 0.0 0.00087 19.7 0.1 4.3 3 1 2 5 5 5 1 EF-hand domain pair UBA PF00627.31 KXG54183.1 - 6.7e-07 29.1 0.0 1.6e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 KXG54183.1 - 6.6e-06 25.3 0.0 0.0024 17.3 0.0 4.4 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.6 KXG54183.1 - 0.00019 21.2 0.0 0.19 11.6 0.0 4.0 4 0 0 4 4 4 1 EF-hand domain pair GAS PF13851.6 KXG54183.1 - 0.00024 20.5 24.8 0.025 13.9 12.3 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding EF-hand_6 PF13405.6 KXG54183.1 - 0.0013 18.5 2.5 1.2 9.3 0.0 5.2 6 0 0 6 6 5 1 EF-hand domain TPR_MLP1_2 PF07926.12 KXG54183.1 - 0.0036 17.3 31.4 0.03 14.4 17.5 2.4 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KXG54183.1 - 0.0066 15.4 29.7 0.18 10.7 15.3 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 KXG54183.1 - 0.0091 16.2 24.2 0.063 13.5 3.8 3.3 1 1 2 3 3 3 2 TATA element modulatory factor 1 TATA binding Macoilin PF09726.9 KXG54183.1 - 0.057 12.0 12.5 0.0098 14.5 7.4 2.0 2 0 0 2 2 2 0 Macoilin family DUF3584 PF12128.8 KXG54183.1 - 0.19 9.2 22.2 0.27 8.7 22.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EF-hand_5 PF13202.6 KXG54183.1 - 0.24 11.0 1.5 0.63 9.6 0.1 2.5 3 0 0 3 3 2 0 EF hand FUSC PF04632.12 KXG54183.1 - 0.5 8.8 8.3 0.73 8.3 8.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family FPP PF05911.11 KXG54183.1 - 1 7.5 20.0 1.5 6.9 20.0 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil AAA_13 PF13166.6 KXG54183.1 - 1 7.9 13.5 1.9 7.1 13.5 1.4 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.8 KXG54183.1 - 1.1 8.5 27.6 0.0078 15.5 14.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF812 PF05667.11 KXG54183.1 - 1.6 7.5 24.5 4.3 6.1 23.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF4201 PF13870.6 KXG54183.1 - 3 7.5 22.5 11 5.8 11.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) ATG16 PF08614.11 KXG54183.1 - 4.4 7.5 33.2 14 5.8 15.7 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 KXG54183.1 - 8.4 6.6 19.5 1.3 9.2 10.0 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family zf-C4H2 PF10146.9 KXG54183.1 - 9 6.5 22.6 8.4e+02 0.1 22.1 3.3 1 1 0 1 1 1 0 Zinc finger-containing protein APH PF01636.23 KXG54184.1 - 1.7e-05 24.8 0.0 5.8e-05 23.1 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family MFS_1 PF07690.16 KXG54185.1 - 5.6e-38 130.8 43.7 5.6e-38 130.8 43.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG54185.1 - 9.5e-12 44.1 16.6 2.4e-11 42.8 16.6 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 KXG54185.1 - 0.0066 16.6 0.8 0.0066 16.6 0.8 2.5 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 PsiE PF06146.12 KXG54185.1 - 0.02 15.3 1.1 0.076 13.4 0.0 2.6 2 0 0 2 2 2 0 Phosphate-starvation-inducible E YtpI PF14007.6 KXG54185.1 - 5.3 7.3 7.9 0.48 10.6 0.2 3.1 3 0 0 3 3 3 0 YtpI-like protein TCR_zetazeta PF11628.8 KXG54186.1 - 3.9 7.2 8.4 55 3.6 0.1 3.5 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 zeta chain E1-E2_ATPase PF00122.20 KXG54187.1 - 1.5e-44 151.7 8.3 1.7e-44 151.5 5.5 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KXG54187.1 - 5.1e-18 66.1 0.0 1.2e-17 64.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXG54187.1 - 1.3e-08 34.3 0.0 4.2e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXG54187.1 - 0.0028 17.5 0.0 0.0074 16.1 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXG54187.1 - 0.053 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Alginate_lyase2 PF08787.11 KXG54188.1 - 0.33 10.8 2.8 5.7 6.7 0.2 2.2 2 0 0 2 2 2 0 Alginate lyase ORC5_C PF14630.6 KXG54189.1 - 5.5e-87 291.9 0.0 7.2e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KXG54189.1 - 6.7e-12 46.1 0.1 2.3e-11 44.4 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 KXG54189.1 - 0.2 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain PUF PF00806.19 KXG54190.1 - 1.4e-59 194.5 12.3 1.2e-07 31.1 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RNA_pol_Rpb2_6 PF00562.28 KXG54191.1 - 4.2e-122 408.0 0.1 4.2e-122 408.0 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXG54191.1 - 5.1e-55 186.1 0.6 8.2e-55 185.5 0.6 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KXG54191.1 - 8.2e-33 112.7 2.7 1.4e-32 112.0 0.3 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KXG54191.1 - 7e-29 100.8 3.6 1.3e-28 99.9 3.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KXG54191.1 - 2.5e-24 85.3 1.8 4.8e-24 84.4 0.6 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KXG54191.1 - 1.4e-19 70.0 0.4 4.1e-19 68.5 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KXG54191.1 - 1.1e-11 45.1 0.5 3.2e-11 43.6 0.5 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 NRDD PF13597.6 KXG54191.1 - 0.034 13.0 0.2 0.084 11.6 0.1 1.6 2 0 0 2 2 2 0 Anaerobic ribonucleoside-triphosphate reductase DUF4246 PF14033.6 KXG54192.1 - 1.3e-134 449.7 0.2 1.6e-134 449.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 KXG54192.1 - 0.1 13.0 0.0 0.35 11.3 0.0 1.9 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase DUF829 PF05705.14 KXG54193.1 - 7.7e-56 189.7 0.0 8.9e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) UFD1 PF03152.14 KXG54194.1 - 2.3e-74 248.6 0.0 2.9e-74 248.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 KXG54194.1 - 0.0018 18.0 0.0 0.046 13.5 0.0 2.3 1 1 1 2 2 2 1 Cell division protein 48 (CDC48), domain 2 GYF PF02213.16 KXG54195.1 - 3.3e-12 45.9 2.2 8.2e-12 44.6 2.2 1.7 1 0 0 1 1 1 1 GYF domain TIP49 PF06068.13 KXG54196.1 - 1.8e-153 510.9 3.0 2.5e-153 510.4 3.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KXG54196.1 - 8.1e-22 77.1 0.3 2.7e-21 75.5 0.3 2.0 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KXG54196.1 - 3.9e-09 37.0 0.7 8.5e-06 26.2 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXG54196.1 - 4.4e-08 33.0 0.4 6.9e-05 22.7 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXG54196.1 - 2.1e-06 28.2 0.5 6.7e-06 26.6 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain DnaB_C PF03796.15 KXG54196.1 - 2.5e-06 27.0 0.9 5.3e-06 26.0 0.9 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 KXG54196.1 - 0.0011 18.4 0.8 0.012 15.1 0.5 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KXG54196.1 - 0.0086 15.8 0.0 5.4 6.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 KXG54196.1 - 0.024 15.0 3.2 0.23 11.8 2.3 2.7 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KXG54196.1 - 0.027 14.5 0.2 0.92 9.5 0.0 2.8 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KXG54196.1 - 0.037 14.3 0.0 0.092 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXG54196.1 - 0.039 13.7 0.6 0.15 11.8 0.6 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXG54196.1 - 0.043 13.4 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXG54196.1 - 0.058 12.9 0.2 0.46 10.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KXG54196.1 - 0.059 12.5 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TFIID-31kDa PF02291.15 KXG54196.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Baculo_PEP_C PF04513.12 KXG54197.1 - 0.00095 19.2 4.6 0.00095 19.2 4.6 9.4 3 2 6 9 9 9 1 Baculovirus polyhedron envelope protein, PEP, C terminus Vps4_C PF09336.10 KXG54197.1 - 0.11 12.5 0.5 0.51 10.4 0.5 2.2 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain POTRA_2 PF08479.11 KXG54197.1 - 0.28 11.0 4.8 0.83 9.5 0.1 4.0 4 0 0 4 4 4 0 POTRA domain, ShlB-type DUF2935 PF11155.8 KXG54197.1 - 2.9 8.2 11.3 2.4 8.5 1.2 5.0 3 3 0 3 3 3 0 Domain of unknown function (DUF2935) Spc7 PF08317.11 KXG54197.1 - 3.3 6.5 89.6 0.16 10.8 0.5 7.3 2 2 5 8 8 8 0 Spc7 kinetochore protein Abhydrolase_1 PF00561.20 KXG54198.1 - 7.1e-28 98.0 0.0 9.5e-22 77.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG54198.1 - 3.1e-13 49.5 0.0 5e-13 48.9 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXG54198.1 - 1.5e-12 48.6 0.0 2.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KXG54198.1 - 2.6e-08 33.9 0.2 1.5e-06 28.1 0.2 2.2 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 KXG54198.1 - 3.3e-07 30.6 0.0 4.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 KXG54198.1 - 0.00011 22.1 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KXG54198.1 - 0.00018 20.5 0.0 0.0013 17.8 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KXG54198.1 - 0.00023 20.3 0.0 0.0016 17.5 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase Esterase PF00756.20 KXG54198.1 - 0.00086 19.0 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Palm_thioest PF02089.15 KXG54198.1 - 0.0025 17.7 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_5 PF12695.7 KXG54198.1 - 0.003 17.4 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KXG54198.1 - 0.0037 16.9 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 KXG54198.1 - 0.0041 17.0 0.0 0.0076 16.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Ser_hydrolase PF06821.13 KXG54198.1 - 0.0051 16.7 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase Ndr PF03096.14 KXG54198.1 - 0.0065 15.2 0.0 0.019 13.6 0.0 1.9 1 1 0 1 1 1 1 Ndr family FSH1 PF03959.13 KXG54198.1 - 0.032 13.9 0.3 0.31 10.7 0.1 2.5 1 1 1 2 2 2 0 Serine hydrolase (FSH1) DUF2974 PF11187.8 KXG54198.1 - 0.038 13.5 0.0 0.079 12.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3530 PF12048.8 KXG54198.1 - 0.051 13.0 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) baeRF_family10 PF18854.1 KXG54198.1 - 0.066 13.5 0.2 0.52 10.5 0.2 2.0 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 UPF0227 PF05728.12 KXG54198.1 - 0.13 12.1 0.2 0.2 11.6 0.2 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) EHN PF06441.12 KXG54199.1 - 2.2e-31 108.4 1.5 2.8e-30 104.8 0.1 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXG54199.1 - 3e-06 27.1 0.0 5.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXG54199.1 - 0.0046 17.6 2.2 0.0085 16.7 2.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Exop_C PF18559.1 KXG54200.1 - 0.065 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Galactose-binding domain-like B12-binding PF02310.19 KXG54201.1 - 0.00035 20.6 0.1 0.00052 20.1 0.1 1.2 1 0 0 1 1 1 1 B12 binding domain REF PF05755.12 KXG54201.1 - 0.023 14.5 0.2 0.025 14.4 0.2 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) F_bP_aldolase PF01116.20 KXG54201.1 - 0.068 12.6 0.0 0.082 12.4 0.0 1.1 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II FAA_hydrolase PF01557.18 KXG54202.1 - 2.5e-56 190.8 0.0 3.2e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.16 KXG54203.1 - 2.8e-39 135.0 22.1 4e-39 134.6 22.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG54203.1 - 2.4e-15 56.4 1.9 2.4e-15 56.4 1.9 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter TRI12 PF06609.13 KXG54203.1 - 2.8e-06 26.0 5.0 1.3e-05 23.8 1.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_7 PF05449.11 KXG54203.1 - 1.3 9.0 4.5 9.3 6.3 0.1 3.5 3 1 0 3 3 3 0 Putative 3TM holin, Phage_holin_3 Fungal_trans PF04082.18 KXG54204.1 - 1.1e-07 31.2 0.5 2e-07 30.3 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CtnDOT_TraJ PF07863.11 KXG54204.1 - 0.13 12.9 0.3 0.39 11.4 0.3 1.7 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon CSN5_C PF18323.1 KXG54206.1 - 0.08 13.9 1.2 0.17 12.8 1.2 1.5 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain ORC6 PF05460.13 KXG54206.1 - 0.22 10.8 8.0 0.24 10.6 8.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PIEZO PF15917.5 KXG54206.1 - 0.71 9.3 2.6 0.99 8.8 2.6 1.2 1 0 0 1 1 1 0 Piezo Dicty_REP PF05086.12 KXG54206.1 - 1.7 6.5 4.5 2 6.3 4.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ORC6 PF05460.13 KXG54207.1 - 0.092 12.0 4.8 0.097 11.9 4.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) WW PF00397.26 KXG54208.1 - 3.1e-05 23.9 3.6 8.5e-05 22.6 3.6 1.8 1 0 0 1 1 1 1 WW domain F-box-like PF12937.7 KXG54209.1 - 0.00038 20.3 1.8 0.00092 19.1 1.8 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KXG54209.1 - 0.049 14.1 0.3 0.049 14.1 0.3 4.3 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Abp2 PF09441.10 KXG54210.1 - 1.9e-85 285.2 0.0 3.4e-85 284.4 0.0 1.4 1 0 0 1 1 1 1 ARS binding protein 2 Med9 PF07544.13 KXG54210.1 - 0.19 11.9 3.0 0.14 12.2 0.8 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Surfac_D-trimer PF09006.11 KXG54210.1 - 0.27 11.1 1.3 0.62 10.0 1.3 1.6 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation PfkB PF00294.24 KXG54212.1 - 2.5e-13 50.0 0.0 2.6e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase WavE PF07507.11 KXG54212.1 - 0.085 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis Brix PF04427.18 KXG54213.1 - 3.7e-29 102.2 0.0 4.9e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain Ras PF00071.22 KXG54215.1 - 8.5e-64 214.0 0.2 9.9e-64 213.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXG54215.1 - 1e-35 122.5 0.2 1.4e-35 122.1 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG54215.1 - 2.3e-13 50.0 0.1 3e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXG54215.1 - 5e-08 33.0 0.1 7.5e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXG54215.1 - 7.2e-05 22.8 0.2 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KXG54215.1 - 0.0003 20.4 0.1 0.0016 18.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXG54215.1 - 0.0003 20.2 0.1 0.00046 19.6 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KXG54215.1 - 0.0026 18.0 0.1 0.014 15.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXG54215.1 - 0.011 15.8 0.2 0.033 14.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXG54215.1 - 0.013 15.9 0.1 0.02 15.3 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 KXG54215.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KXG54215.1 - 0.02 15.4 0.2 0.03 14.8 0.2 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KXG54215.1 - 0.03 14.1 0.1 0.063 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KXG54215.1 - 0.05 13.0 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 KXG54215.1 - 0.062 13.1 0.6 0.11 12.3 0.5 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AEP1 PF17049.5 KXG54215.1 - 0.085 11.9 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 FeoB_N PF02421.18 KXG54215.1 - 0.093 12.3 0.1 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B MCM PF00493.23 KXG54215.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 KXG54215.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Chromo PF00385.24 KXG54216.1 - 4.6e-06 26.4 2.0 4.6e-06 26.4 2.0 2.3 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_2 PF07724.14 KXG54217.1 - 1.9e-37 129.0 0.0 1.9e-36 125.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KXG54217.1 - 2.1e-14 54.1 0.0 4.5e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KXG54217.1 - 2.2e-08 34.1 0.0 4.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KXG54217.1 - 6.6e-06 26.2 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXG54217.1 - 0.0001 21.8 0.2 0.013 14.9 0.0 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KXG54217.1 - 0.00044 20.0 0.0 0.099 12.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 KXG54217.1 - 0.00049 20.4 0.8 0.0096 16.2 0.4 2.6 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 KXG54217.1 - 0.0011 18.8 0.2 0.03 14.1 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXG54217.1 - 0.0019 18.6 1.5 0.026 14.9 0.1 2.9 1 1 2 3 3 3 1 AAA ATPase domain AAA_24 PF13479.6 KXG54217.1 - 0.0045 16.7 0.0 0.0076 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXG54217.1 - 0.0068 16.2 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KXG54217.1 - 0.01 16.4 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXG54217.1 - 0.053 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KXG54217.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MCM PF00493.23 KXG54217.1 - 0.071 12.2 0.1 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 KXG54217.1 - 0.072 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 KXG54217.1 - 0.072 13.2 0.0 0.35 11.0 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 KXG54217.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXG54217.1 - 0.17 11.8 0.2 1.2 9.0 0.2 2.1 1 1 0 1 1 1 0 NACHT domain SLX9 PF15341.6 KXG54218.1 - 5.6e-34 117.4 13.0 6.8e-34 117.1 13.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 PIN_8 PF18476.1 KXG54218.1 - 0.028 14.3 2.1 0.034 14.0 2.1 1.1 1 0 0 1 1 1 0 PIN like domain Neugrin PF06413.11 KXG54218.1 - 0.034 14.2 3.4 0.046 13.7 3.4 1.2 1 0 0 1 1 1 0 Neugrin NAD_Gly3P_dh_N PF01210.23 KXG54219.1 - 8.9e-47 159.0 0.2 2.5e-46 157.5 0.1 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KXG54219.1 - 4.5e-40 137.2 0.1 8.5e-40 136.3 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 KXG54219.1 - 0.11 13.2 0.0 19 6.0 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent hDGE_amylase PF14701.6 KXG54220.1 - 3.8e-182 606.3 0.0 5e-182 605.9 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KXG54220.1 - 4.2e-117 391.3 0.0 6.7e-117 390.7 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KXG54220.1 - 1e-84 284.2 0.0 1.6e-84 283.5 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KXG54220.1 - 4.3e-29 100.5 0.1 9.5e-29 99.4 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KXG54220.1 - 0.099 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 Alpha amylase, catalytic domain FAD_binding_4 PF01565.23 KXG54221.1 - 8.3e-21 74.2 1.0 1.5e-20 73.4 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG54221.1 - 6.3e-09 35.8 1.6 1.4e-08 34.7 1.6 1.5 1 0 0 1 1 1 1 Berberine and berberine like Autoind_synth PF00765.17 KXG54221.1 - 0.0095 15.5 0.2 0.78 9.3 0.0 2.2 1 1 1 2 2 2 2 Autoinducer synthase RSN1_7TM PF02714.15 KXG54224.1 - 1.3e-80 270.7 19.6 1.3e-80 270.7 19.6 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KXG54224.1 - 8.5e-42 143.4 0.0 1.2e-41 142.9 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KXG54224.1 - 3.8e-40 137.2 0.6 1.4e-39 135.4 0.5 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport Anoctamin PF04547.12 KXG54224.1 - 0.0055 15.6 1.2 0.0055 15.6 1.2 2.2 3 0 0 3 3 3 1 Calcium-activated chloride channel F-box-like PF12937.7 KXG54225.1 - 2e-06 27.6 0.1 6.9e-06 25.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXG54225.1 - 0.029 14.2 0.0 0.11 12.4 0.0 2.1 1 0 0 1 1 1 0 F-box domain DAHP_synth_1 PF00793.20 KXG54226.1 - 2.1e-101 338.4 0.0 3.2e-101 337.8 0.0 1.2 1 0 0 1 1 1 1 DAHP synthetase I family AIG2_2 PF13772.6 KXG54227.1 - 0.0019 18.5 0.4 0.013 15.8 0.1 2.4 3 0 0 3 3 3 1 AIG2-like family Cytochrom_C1 PF02167.15 KXG54228.1 - 7.1e-90 300.5 0.0 8.8e-90 300.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KXG54228.1 - 0.0048 17.2 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KXG54228.1 - 0.14 13.3 0.6 0.76 11.0 0.2 2.4 3 1 0 3 3 3 0 Cytochrome c Sec10 PF07393.11 KXG54229.1 - 8.8e-182 606.2 0.7 1e-181 606.0 0.7 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KXG54229.1 - 1.9e-05 24.5 0.0 4.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXG54229.1 - 0.0021 17.9 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain CAP PF00188.26 KXG54230.1 - 2.2e-21 77.0 3.3 9.1e-21 75.0 3.3 2.0 1 1 0 1 1 1 1 Cysteine-rich secretory protein family eIF2A PF08662.11 KXG54231.1 - 3.6e-36 124.9 7.0 6.9e-34 117.4 4.5 3.8 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KXG54231.1 - 3.7e-06 26.7 0.0 7.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KXG54231.1 - 0.024 15.5 0.9 5.8 8.0 0.1 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat SWIB PF02201.18 KXG54232.1 - 3.4e-29 100.5 0.2 7e-29 99.5 0.2 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KXG54232.1 - 3.1e-14 52.6 1.0 5.5e-14 51.8 1.0 1.4 1 0 0 1 1 1 1 DEK C terminal domain Ndc1_Nup PF09531.10 KXG54232.1 - 5.7 5.5 6.1 6.5 5.3 6.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MutS_V PF00488.21 KXG54234.1 - 2.7e-63 213.4 0.1 5.4e-63 212.4 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXG54234.1 - 1.9e-33 116.3 1.8 1.9e-33 116.3 1.8 1.8 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KXG54234.1 - 8.8e-09 35.8 0.0 2.3e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KXG54234.1 - 2.8e-05 24.4 0.0 6.9e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_30 PF13604.6 KXG54234.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain WD40 PF00400.32 KXG54235.1 - 3.5e-60 198.6 26.6 8.6e-11 42.2 0.1 9.1 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG54235.1 - 1e-17 64.2 6.1 0.00071 19.8 0.1 6.2 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXG54235.1 - 1.1e-08 35.2 0.2 0.0068 16.3 0.0 3.5 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXG54235.1 - 1.5e-07 30.7 0.9 0.084 11.8 0.0 5.1 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXG54235.1 - 1.4e-05 23.9 5.9 0.49 9.0 0.1 5.4 4 2 1 5 5 5 2 Nucleoporin Nup120/160 NLE PF08154.12 KXG54235.1 - 3.6e-05 24.2 0.0 7.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40_like PF17005.5 KXG54235.1 - 0.0023 17.3 0.0 3.1 7.0 0.0 3.6 4 0 0 4 4 4 1 WD40-like domain FAD_binding_9 PF08021.11 KXG54235.1 - 0.012 15.8 0.1 0.11 12.7 0.0 2.4 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain DUF4550 PF15084.6 KXG54235.1 - 0.025 15.0 0.0 0.27 11.6 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4550) 120_Rick_ant PF12574.8 KXG54235.1 - 0.1 11.8 0.7 0.56 9.4 0.1 2.1 2 0 0 2 2 2 0 120 KDa Rickettsia surface antigen PALB2_WD40 PF16756.5 KXG54235.1 - 0.2 10.5 4.0 12 4.7 0.0 3.9 3 2 2 5 5 5 0 Partner and localizer of BRCA2 WD40 domain Asp PF00026.23 KXG54236.1 - 2.4e-41 142.2 0.2 3.2e-41 141.8 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KXG54236.1 - 3.6e-06 27.5 1.1 0.011 16.3 0.8 3.5 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KXG54236.1 - 0.00012 22.5 0.8 0.093 13.3 0.1 3.1 4 0 0 4 4 4 2 gag-polyprotein putative aspartyl protease Ank PF00023.30 KXG54237.1 - 2.2e-27 94.2 0.6 1.8e-06 28.1 0.5 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 KXG54237.1 - 4.6e-27 94.4 0.0 1e-14 54.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG54237.1 - 2.2e-22 76.7 0.1 0.00027 21.1 0.1 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KXG54237.1 - 3.4e-22 78.5 2.3 6.6e-10 39.3 0.1 3.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG54237.1 - 4.4e-22 77.9 0.6 1.1e-06 28.8 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) bZIP_1 PF00170.21 KXG54237.1 - 0.038 14.1 1.8 0.063 13.4 1.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KXG54237.1 - 0.28 11.3 1.5 0.46 10.6 1.5 1.3 1 0 0 1 1 1 0 Basic region leucine zipper RTA1 PF04479.13 KXG54238.1 - 5.2e-48 163.4 8.4 8.2e-48 162.8 8.4 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF1729 PF08354.10 KXG54239.1 - 4.5e-151 502.7 0.0 6.2e-151 502.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KXG54239.1 - 6.7e-66 223.0 0.0 3.7e-65 220.5 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain FAS_meander PF17951.1 KXG54239.1 - 3.1e-41 140.6 0.0 7.7e-41 139.3 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 KXG54239.1 - 4.5e-36 124.8 0.0 1.1e-35 123.6 0.0 1.7 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 KXG54239.1 - 4.7e-26 90.8 0.0 9.7e-26 89.7 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 KXG54239.1 - 1.3e-13 51.1 0.0 3.3e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 KXG54239.1 - 4e-13 49.6 0.1 1.4e-11 44.7 0.0 2.7 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 4HBT_2 PF13279.6 KXG54239.1 - 3.1e-06 27.7 0.0 6e-05 23.5 0.0 2.8 3 0 0 3 3 3 1 Thioesterase-like superfamily ABC_tran PF00005.27 KXG54240.1 - 3.7e-48 163.5 0.0 4.8e-27 95.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXG54240.1 - 7.2e-32 111.1 35.9 3.2e-28 99.2 13.2 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KXG54240.1 - 9.7e-10 38.3 0.6 2.6e-06 27.0 0.2 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXG54240.1 - 4.5e-08 33.3 0.7 0.24 11.1 0.0 4.3 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXG54240.1 - 5.3e-06 26.4 0.1 0.087 12.7 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KXG54240.1 - 2.4e-05 24.0 0.2 0.17 11.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXG54240.1 - 2.8e-05 24.4 0.6 0.04 14.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KXG54240.1 - 0.00011 22.3 0.4 0.14 12.3 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KXG54240.1 - 0.00021 21.7 0.1 0.87 9.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 KXG54240.1 - 0.00033 20.8 0.8 0.2 11.9 0.2 3.1 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KXG54240.1 - 0.00057 20.1 0.0 0.18 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KXG54240.1 - 0.0014 18.4 0.2 0.6 9.8 0.1 2.6 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 KXG54240.1 - 0.0028 17.8 0.8 0.36 10.9 0.5 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 KXG54240.1 - 0.0049 17.4 0.1 2.4 8.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KXG54240.1 - 0.0062 16.3 0.0 2.2 7.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 KXG54240.1 - 0.01 16.2 0.1 7.4 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 KXG54240.1 - 0.016 15.8 0.0 3.2 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KXG54240.1 - 0.017 15.1 0.1 0.19 11.6 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA PF00004.29 KXG54240.1 - 0.023 15.1 0.1 2.2 8.7 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KXG54240.1 - 0.034 13.7 0.1 11 5.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 KXG54240.1 - 0.037 13.7 0.4 7 6.2 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.17 KXG54240.1 - 0.046 13.5 0.3 9 6.0 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 KXG54240.1 - 0.049 13.6 0.1 12 5.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KXG54240.1 - 0.051 13.3 0.1 11 5.6 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Septin PF00735.18 KXG54240.1 - 0.061 12.6 0.1 4.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.23 KXG54240.1 - 0.11 12.5 0.7 17 5.4 0.0 2.4 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.12 KXG54240.1 - 0.17 11.8 0.6 22 4.9 0.0 2.9 3 0 0 3 3 3 0 NACHT domain NB-ARC PF00931.22 KXG54240.1 - 0.19 10.9 0.1 11 5.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 KXG54240.1 - 0.25 10.7 0.7 21 4.3 0.1 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family cobW PF02492.19 KXG54240.1 - 0.33 10.5 1.3 10 5.6 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Fas_alpha_ACP PF18325.1 KXG54241.1 - 2.1e-56 190.7 0.0 4.7e-56 189.6 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 KXG54241.1 - 7.7e-39 133.4 0.0 2.3e-38 131.9 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 KXG54241.1 - 2.3e-19 70.0 0.2 4.8e-19 68.9 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXG54241.1 - 7.2e-14 51.8 0.0 2.9e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KXG54241.1 - 0.0031 16.9 0.1 0.0073 15.7 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain p450 PF00067.22 KXG54242.1 - 1.3e-73 248.4 0.0 1.7e-73 248.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_4 PF01063.19 KXG54243.1 - 8.2e-27 94.5 0.0 1e-26 94.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Ank_4 PF13637.6 KXG54244.1 - 1.9e-16 60.2 0.5 1.4e-08 35.1 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG54244.1 - 1e-10 41.7 0.3 0.00021 21.5 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXG54244.1 - 1e-10 42.1 0.2 1.6e-10 41.5 0.2 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXG54244.1 - 2.2e-09 37.3 0.7 0.00011 22.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KXG54244.1 - 1.8e-07 30.9 0.1 0.0023 18.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat NAT PF04768.13 KXG54245.1 - 4e-12 46.1 0.0 8.4e-12 45.1 0.0 1.6 1 1 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 KXG54245.1 - 7.1e-08 32.3 0.0 1.4e-06 28.1 0.0 2.4 2 1 0 2 2 2 1 Amino acid kinase family Tom7 PF08038.12 KXG54245.1 - 0.0053 16.4 0.0 0.026 14.2 0.0 2.0 2 0 0 2 2 2 1 TOM7 family EAV_GP5 PF15981.5 KXG54245.1 - 0.018 15.5 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 Envelope glycoprotein GP 5 of equine arteritis virus Se-cys_synth_N PF12390.8 KXG54245.1 - 0.34 11.2 2.5 10 6.5 0.0 3.6 3 0 0 3 3 3 0 Selenocysteine synthase N terminal AMP-binding PF00501.28 KXG54246.1 - 0 1309.6 0.5 4.3e-78 262.8 0.0 8.0 6 1 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 KXG54246.1 - 0 1038.3 0.0 2.8e-54 184.5 0.0 9.5 9 1 0 9 9 9 7 Condensation domain PP-binding PF00550.25 KXG54246.1 - 1.9e-78 258.8 6.4 3.7e-11 43.2 0.0 8.0 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXG54246.1 - 1.6e-12 48.2 0.0 0.46 11.5 0.0 6.1 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 KXG54246.1 - 0.00028 20.7 0.1 2.8 7.6 0.0 5.3 6 0 0 6 6 6 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Transferase PF02458.15 KXG54246.1 - 0.046 12.4 0.0 19 3.8 0.0 3.7 4 0 0 4 4 4 0 Transferase family AATase PF07247.12 KXG54246.1 - 0.075 11.6 0.1 1.4 7.4 0.0 2.8 2 0 0 2 2 2 0 Alcohol acetyltransferase DUF5122 PF17164.4 KXG54246.1 - 0.16 12.3 1.6 21 5.5 0.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller PALP PF00291.25 KXG54247.1 - 7.8e-52 176.5 0.0 9.2e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 KXG54247.1 - 0.09 12.8 0.0 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Velvet PF11754.8 KXG54249.1 - 1.2e-90 303.9 0.0 1.5e-90 303.5 0.0 1.1 1 0 0 1 1 1 1 Velvet factor DUF2076 PF09849.9 KXG54249.1 - 6.8 6.7 7.1 11 6.0 7.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Fungal_trans_2 PF11951.8 KXG54250.1 - 2.1e-06 26.8 1.3 4.2e-06 25.8 0.0 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain DUF3602 PF12223.8 KXG54251.1 - 1.8e-16 60.5 12.3 3e-14 53.4 0.4 2.9 2 2 1 3 3 3 2 Protein of unknown function (DUF3602) ATG16 PF08614.11 KXG54251.1 - 0.00039 20.7 4.4 0.00047 20.4 4.4 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) RVT_2 PF07727.14 KXG54252.1 - 5.1e-07 29.6 0.1 7.1e-07 29.1 0.1 1.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pam17 PF08566.10 KXG54253.1 - 1.7e-65 219.8 0.0 2.2e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 ECH_1 PF00378.20 KXG54254.1 - 6.3e-44 150.2 0.0 8.4e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXG54254.1 - 6.4e-22 78.5 0.3 4.2e-20 72.5 0.1 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Fungal_trans_2 PF11951.8 KXG54255.1 - 3e-49 167.9 0.1 6.8e-49 166.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG54255.1 - 1.3e-09 38.0 7.9 2.5e-09 37.1 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Far-17a_AIG1 PF04750.14 KXG54256.1 - 3e-63 212.8 5.1 3.7e-63 212.5 5.1 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein MFS_1 PF07690.16 KXG54257.1 - 2.6e-26 92.4 30.1 4.2e-26 91.7 30.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF485 PF04341.12 KXG54257.1 - 6.5 6.8 6.6 3.1 7.8 2.4 2.7 1 1 1 2 2 2 0 Protein of unknown function, DUF485 DUF4381 PF14316.6 KXG54259.1 - 0.0056 16.9 0.7 0.011 15.9 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DUF456 PF04306.13 KXG54259.1 - 0.012 16.0 0.4 0.038 14.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF456) TMEM154 PF15102.6 KXG54259.1 - 0.016 15.1 0.1 0.05 13.5 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family DUF4079 PF13301.6 KXG54259.1 - 0.024 14.8 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) BatD PF13584.6 KXG54259.1 - 0.027 13.3 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance LapA_dom PF06305.11 KXG54259.1 - 0.046 13.5 0.4 0.046 13.5 0.4 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Synaptobrevin PF00957.21 KXG54259.1 - 0.05 13.4 0.2 0.05 13.4 0.2 1.5 2 0 0 2 2 2 0 Synaptobrevin Saf_2TM PF18303.1 KXG54259.1 - 0.087 12.4 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF3619 PF12279.8 KXG54259.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Pro_isomerase PF00160.21 KXG54260.1 - 6.5e-50 169.5 0.1 1.2e-49 168.6 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KXG54260.1 - 3.3e-11 43.5 0.0 0.029 15.2 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG54260.1 - 0.063 13.6 0.0 19 5.6 0.0 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXG54260.1 - 0.066 12.2 0.1 1.9 7.4 0.0 2.5 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cpn60_TCP1 PF00118.24 KXG54261.1 - 1.8e-144 482.1 13.2 2e-144 481.9 13.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 KXG54261.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Glyco_hydro_76 PF03663.14 KXG54262.1 - 4.2e-140 467.4 18.4 4.9e-140 467.2 18.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cloacin_immun PF03513.14 KXG54262.1 - 0.018 15.3 0.0 0.054 13.8 0.0 1.8 1 0 0 1 1 1 0 Cloacin immunity protein Pkinase PF00069.25 KXG54263.1 - 3.7e-40 138.0 0.0 1.2e-39 136.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 KXG54263.1 - 7.8e-40 136.0 0.0 1.8e-39 134.8 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 KXG54263.1 - 4.7e-20 72.0 0.0 1.4e-19 70.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 KXG54263.1 - 0.00049 19.9 0.0 0.72 9.9 0.0 2.9 2 0 0 2 2 2 2 PQQ enzyme repeat Cytokin_check_N PF10407.9 KXG54263.1 - 0.0013 18.6 0.0 0.0038 17.1 0.0 1.7 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Pkinase_fungal PF17667.1 KXG54263.1 - 0.012 14.5 0.0 0.012 14.5 0.0 3.7 4 2 0 4 4 2 0 Fungal protein kinase PQQ_2 PF13360.6 KXG54263.1 - 0.012 15.2 0.6 0.41 10.2 0.1 2.3 1 1 1 3 3 3 0 PQQ-like domain CPDase PF07823.11 KXG54263.1 - 0.018 14.8 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein Kdo PF06293.14 KXG54263.1 - 0.022 14.1 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KXG54263.1 - 0.08 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PAC1 PF16094.5 KXG54263.1 - 0.59 9.2 1.8 0.74 8.9 0.0 2.0 2 0 0 2 2 1 0 Proteasome assembly chaperone 4 ADH_N PF08240.12 KXG54264.1 - 1.1e-24 86.5 0.7 2e-24 85.6 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Aminotran_4 PF01063.19 KXG54264.1 - 2.3e-22 80.0 0.0 3.3e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV ADH_zinc_N PF00107.26 KXG54264.1 - 6.2e-12 45.6 0.0 3.1e-07 30.4 0.0 2.7 2 0 0 2 2 2 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXG54264.1 - 0.00063 19.2 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N_assoc PF13823.6 KXG54264.1 - 0.042 13.8 1.0 0.1 12.5 1.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated BNR_2 PF13088.6 KXG54264.1 - 0.14 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 BNR repeat-like domain AlaDh_PNT_C PF01262.21 KXG54264.1 - 0.15 11.4 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain LPD22 PF18834.1 KXG54264.1 - 0.74 10.1 2.2 1.1 9.5 0.2 2.2 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 Na_H_Exchanger PF00999.21 KXG54266.1 - 2.5e-58 197.7 48.9 3.5e-58 197.2 48.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FAD_binding_7 PF03441.14 KXG54268.1 - 7e-82 273.8 1.0 1.5e-81 272.7 1.0 1.6 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KXG54268.1 - 3.5e-43 147.4 0.9 6.8e-43 146.5 0.2 1.8 2 0 0 2 2 2 1 DNA photolyase Fungal_trans PF04082.18 KXG54268.1 - 1.6e-18 66.7 0.0 7.3e-18 64.6 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain APC_rep PF18797.1 KXG54268.1 - 0.058 14.3 0.0 0.22 12.5 0.0 2.0 1 0 0 1 1 1 0 Adenomatous polyposis coli (APC) repeat AMP-binding PF00501.28 KXG54270.1 - 6e-66 222.8 0.0 8.6e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG54270.1 - 0.018 16.0 0.0 0.046 14.7 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain adh_short PF00106.25 KXG54271.1 - 7.5e-16 58.2 0.1 3.5e-13 49.5 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KXG54271.1 - 5.3e-08 33.0 0.3 7.8e-08 32.4 0.3 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KXG54271.1 - 1.5e-07 31.3 0.1 2.6e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase p450 PF00067.22 KXG54272.1 - 1e-44 153.1 0.0 1.3e-44 152.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_25 PF13649.6 KXG54273.1 - 1.2e-07 32.3 0.0 1.3e-06 29.0 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG54273.1 - 3.2e-06 27.0 0.0 1e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG54273.1 - 9.2e-05 23.1 0.0 0.00036 21.2 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG54273.1 - 0.00059 20.4 0.0 0.0016 19.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG54273.1 - 0.049 13.5 0.0 0.082 12.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Abhydrolase_6 PF12697.7 KXG54274.1 - 2e-15 58.0 1.9 2e-15 58.0 1.9 1.7 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KXG54274.1 - 0.04 13.8 0.1 0.083 12.7 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KXG54274.1 - 0.16 11.7 0.0 1 9.0 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein Aldo_ket_red PF00248.21 KXG54275.1 - 1.7e-42 145.7 0.0 2.1e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_4 PF01565.23 KXG54276.1 - 3.7e-22 78.6 3.1 7e-22 77.7 3.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG54276.1 - 9.8e-13 48.0 2.1 2e-12 47.0 2.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KXG54276.1 - 0.15 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Mito_carr PF00153.27 KXG54277.1 - 2.8e-51 171.4 6.8 1.6e-18 66.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TrbC_Ftype PF09673.10 KXG54277.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein DUF2067 PF09840.9 KXG54277.1 - 0.2 11.2 0.1 0.98 9.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) TauD PF02668.16 KXG54278.1 - 1.4e-37 129.9 0.1 2.1e-37 129.4 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SapC PF07277.11 KXG54278.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 SapC MFS_1 PF07690.16 KXG54279.1 - 1.4e-13 50.5 21.3 1.4e-13 50.5 21.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXG54279.1 - 1.4e-08 34.6 4.0 3.4e-08 33.4 4.0 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 KXG54279.1 - 0.0021 17.0 9.2 0.0021 17.0 9.2 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter HET PF06985.11 KXG54280.1 - 4e-07 30.5 0.9 1.3e-06 28.8 0.9 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Acyl-CoA_dh_1 PF00441.24 KXG54281.1 - 1.8e-31 109.4 0.5 4.2e-31 108.2 0.5 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXG54281.1 - 1.4e-18 67.6 0.2 3.7e-18 66.2 0.2 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXG54281.1 - 4.4e-18 65.3 0.0 8.1e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXG54281.1 - 5e-14 52.7 2.1 1.3e-13 51.4 0.3 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain ILVD_EDD PF00920.21 KXG54282.1 - 8e-208 691.2 0.2 9.3e-208 691.0 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.18 KXG54282.1 - 0.0053 17.0 0.0 0.02 15.1 0.0 2.0 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain DDE_1 PF03184.19 KXG54283.1 - 2.2e-40 138.1 0.3 5.1e-40 137.0 0.1 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KXG54283.1 - 3.6e-12 46.1 0.2 9.1e-12 44.8 0.2 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Arch_fla_DE PF04659.13 KXG54283.1 - 0.034 14.0 1.2 1 9.3 0.2 2.5 2 0 0 2 2 2 0 Archaeal flagella protein DDE_3 PF13358.6 KXG54283.1 - 0.052 13.3 0.2 0.14 11.9 0.2 1.8 1 1 0 1 1 1 0 DDE superfamily endonuclease VSP PF03302.13 KXG54284.1 - 4.6e-06 25.8 0.2 7.7e-06 25.0 0.2 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Cu_bind_like PF02298.17 KXG54284.1 - 0.014 15.3 0.1 0.046 13.7 0.1 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain Pyr_redox_2 PF07992.14 KXG54285.1 - 1.4e-17 63.9 0.0 2.2e-11 43.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG54285.1 - 0.00055 19.2 0.1 0.0076 15.4 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KXG54285.1 - 0.00092 18.4 0.0 0.77 8.8 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXG54285.1 - 0.0027 16.8 0.1 0.65 9.0 0.1 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 KXG54285.1 - 0.0027 16.5 0.4 0.02 13.6 0.0 2.4 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 KXG54285.1 - 0.005 16.1 0.5 2 7.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SmpB PF01668.18 KXG54285.1 - 0.047 13.6 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 SmpB protein Thi4 PF01946.17 KXG54285.1 - 0.073 12.3 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KXG54285.1 - 0.076 13.0 3.0 1 9.4 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXG54285.1 - 0.33 10.0 4.3 0.79 8.7 2.3 2.4 2 1 1 3 3 3 0 FAD binding domain Glyco_hydro_28 PF00295.17 KXG54286.1 - 1.3e-50 172.3 8.0 2.6e-50 171.3 8.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 adh_short PF00106.25 KXG54286.1 - 4.5e-41 140.5 0.0 7.6e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG54286.1 - 1.3e-36 126.3 0.0 2e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG54286.1 - 1.2e-11 44.8 0.0 2.2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 KR domain MPC PF03650.13 KXG54287.1 - 2.8e-48 162.6 0.7 3.8e-48 162.2 0.7 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF2863 PF11062.8 KXG54287.1 - 0.024 13.0 1.5 0.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2863) L51_S25_CI-B8 PF05047.16 KXG54288.1 - 7.3e-14 51.4 0.0 9.1e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain CaM_binding PF07839.11 KXG54288.1 - 0.06 14.1 0.0 0.074 13.8 0.0 1.1 1 0 0 1 1 1 0 Plant calmodulin-binding domain LigB PF02900.18 KXG54289.1 - 1.9e-34 119.0 0.0 2.5e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Sel1 PF08238.12 KXG54290.1 - 3.2e-45 151.6 26.6 4e-08 33.7 0.1 7.5 7 0 0 7 7 7 7 Sel1 repeat TPR_20 PF14561.6 KXG54290.1 - 0.075 13.4 0.8 0.21 12.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat CBP4 PF07960.11 KXG54291.1 - 2.7e-29 101.6 2.7 3.8e-29 101.1 2.7 1.1 1 0 0 1 1 1 1 CBP4 Rgp1 PF08737.10 KXG54291.1 - 0.0093 15.2 0.9 0.01 15.0 0.9 1.0 1 0 0 1 1 1 1 Rgp1 Trp_oprn_chp PF09534.10 KXG54291.1 - 0.071 12.9 0.8 0.15 11.8 0.8 1.6 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Tmemb_161AB PF10268.9 KXG54291.1 - 0.3 9.7 0.2 0.41 9.2 0.1 1.3 1 1 0 1 1 1 0 Predicted transmembrane protein 161AB DUF4407 PF14362.6 KXG54291.1 - 2.2 7.6 6.9 2.6 7.3 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KXG54291.1 - 3.8 7.8 12.4 4.8 7.5 12.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Glyco_hydro_76 PF03663.14 KXG54292.1 - 1.3e-141 472.3 10.6 1.6e-141 472.1 10.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 VCBS PF13517.6 KXG54292.1 - 0.12 13.0 1.1 13 6.5 0.1 2.7 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Glyco_hydro_88 PF07470.13 KXG54292.1 - 3.6 6.6 11.8 0.48 9.4 1.3 2.6 1 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 Abhydrolase_2 PF02230.16 KXG54293.1 - 1.7e-54 184.9 0.0 2.8e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase AATase PF07247.12 KXG54293.1 - 2.7e-19 69.1 0.0 4.2e-18 65.2 0.0 2.1 1 1 0 1 1 1 1 Alcohol acetyltransferase Peptidase_S9 PF00326.21 KXG54293.1 - 6.8e-08 32.2 0.1 0.00011 21.8 0.0 3.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXG54293.1 - 0.00049 19.4 0.1 0.04 13.2 0.0 3.0 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXG54293.1 - 0.0062 17.2 0.0 0.034 14.7 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 KXG54293.1 - 0.0077 15.9 0.0 0.036 13.7 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Condensation PF00668.20 KXG54293.1 - 0.051 12.2 0.0 0.4 9.3 0.0 2.0 2 0 0 2 2 2 0 Condensation domain Abhydrolase_3 PF07859.13 KXG54293.1 - 0.052 13.4 0.0 0.32 10.8 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold LIP PF03583.14 KXG54293.1 - 0.076 12.3 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Abhydro_lipase PF04083.16 KXG54293.1 - 0.091 12.4 0.0 15 5.2 0.0 2.4 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF1581 PF07619.11 KXG54293.1 - 0.16 12.1 0.1 0.55 10.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1581) Endonuc_BglI PF14562.6 KXG54294.1 - 0.17 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BglI Ctr PF04145.15 KXG54295.1 - 1.1e-32 113.7 0.2 1.4e-32 113.4 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF945 PF06097.11 KXG54295.1 - 0.2 10.7 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) UbiA PF01040.18 KXG54297.1 - 6.7e-30 104.2 10.7 1.2e-29 103.4 10.7 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family FAD_binding_4 PF01565.23 KXG54297.1 - 9e-30 103.2 1.6 1.8e-29 102.3 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG54297.1 - 1.2e-09 38.1 0.0 2.3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like MNHE PF01899.16 KXG54297.1 - 1.5 8.6 8.5 1 9.1 4.3 2.6 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit Amidohydro_2 PF04909.14 KXG54298.1 - 2.5e-38 132.5 2.3 3.7e-38 132.0 2.3 1.3 1 1 0 1 1 1 1 Amidohydrolase p450 PF00067.22 KXG54299.1 - 3.3e-55 187.7 0.0 4e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sdh_cyt PF01127.22 KXG54301.1 - 2.7e-26 92.0 3.5 3.3e-26 91.7 3.5 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit HAD_2 PF13419.6 KXG54303.1 - 0.00059 20.0 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Prenyltrans PF00432.21 KXG54303.1 - 0.14 11.9 1.5 0.24 11.2 0.2 2.2 2 1 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Ferric_reduct PF01794.19 KXG54304.1 - 9.3e-22 77.5 15.7 1.8e-21 76.5 15.7 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXG54304.1 - 1.2e-21 76.9 0.0 2.6e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KXG54304.1 - 9e-18 64.9 0.0 1.7e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF1687 PF07955.11 KXG54305.1 - 3.1e-27 95.6 0.0 3.8e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Pkinase PF00069.25 KXG54306.1 - 1.3e-59 201.8 0.0 1.3e-58 198.5 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG54306.1 - 3e-28 98.8 0.4 1.4e-19 70.4 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KXG54306.1 - 0.0003 21.4 0.6 0.001 19.7 0.6 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KXG54306.1 - 0.0018 17.6 0.6 0.027 13.8 0.0 2.6 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KXG54306.1 - 0.011 15.7 4.3 0.39 10.6 0.0 3.3 3 1 1 4 4 4 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXG54306.1 - 0.028 13.4 0.0 0.051 12.5 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KXG54306.1 - 0.15 11.4 0.9 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EutQ PF06249.12 KXG54307.1 - 5e-12 45.8 0.0 6e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 KXG54307.1 - 1.6e-09 37.3 0.1 2e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KXG54307.1 - 1.8e-05 24.3 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Pirin PF02678.16 KXG54307.1 - 0.03 14.3 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Pirin Cupin_6 PF12852.7 KXG54307.1 - 0.054 13.2 0.0 0.48 10.1 0.0 1.9 2 0 0 2 2 2 0 Cupin Cupin_1 PF00190.22 KXG54307.1 - 0.079 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Cupin GST_N_3 PF13417.6 KXG54308.1 - 2.2e-09 37.6 0.0 4.2e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXG54308.1 - 3.3e-09 37.0 0.0 5.8e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXG54308.1 - 3.5e-09 36.8 0.0 1.4e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXG54308.1 - 7.3e-07 29.1 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXG54308.1 - 8.5e-07 29.1 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXG54308.1 - 4.3e-06 26.8 0.0 6.6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ADH_zinc_N_2 PF13602.6 KXG54309.1 - 6.3e-21 75.8 0.0 1.2e-20 74.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXG54309.1 - 6e-17 61.8 0.0 1.3e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 KXG54309.1 - 0.0063 16.3 0.3 0.009 15.8 0.3 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Epimerase PF01370.21 KXG54309.1 - 0.034 13.6 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2855 PF11017.8 KXG54309.1 - 0.17 11.6 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Fungal_trans_2 PF11951.8 KXG54310.1 - 7.1e-56 189.7 0.4 1e-55 189.1 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG54310.1 - 6.5e-05 23.0 13.1 0.00011 22.3 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ICL PF00463.21 KXG54311.1 - 4.9e-188 625.9 0.0 5.7e-188 625.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KXG54311.1 - 1.6e-09 37.6 0.0 2.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase RAP1 PF07218.11 KXG54312.1 - 0.62 8.3 4.1 0.62 8.3 4.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Chitin_synth_1 PF01644.17 KXG54313.1 - 1.8e-68 229.6 0.0 2.8e-68 229.0 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KXG54313.1 - 7.2e-27 94.2 0.0 4.8e-21 75.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 KXG54313.1 - 2.5e-26 91.4 0.1 7.2e-26 90.0 0.1 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 KXG54313.1 - 3.2e-09 37.0 0.0 3.2e-09 37.0 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXG54313.1 - 0.0062 16.5 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF3237 PF11578.8 KXG54314.1 - 2.5e-35 121.5 0.0 4.1e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.15 KXG54314.1 - 0.00047 20.1 6.3 0.08 13.0 0.3 2.7 3 0 0 3 3 3 2 BED zinc finger zf-C2H2_2 PF12756.7 KXG54314.1 - 0.031 14.6 4.1 2.9 8.3 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS91 PF14319.6 KXG54314.1 - 0.64 10.1 11.5 0.79 9.8 2.2 2.2 2 0 0 2 2 2 0 Transposase zinc-binding domain PyrI_C PF02748.15 KXG54314.1 - 1 9.3 6.0 7.3 6.6 0.5 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Rad21_Rec8_N PF04825.13 KXG54315.1 - 2.3e-31 108.2 0.0 5e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KXG54315.1 - 0.00023 20.4 0.0 0.00072 18.8 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein XRCC4 PF06632.12 KXG54315.1 - 0.021 13.7 3.8 0.042 12.7 3.8 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 NAT PF04768.13 KXG54316.1 - 3.2e-55 186.4 0.2 6.9e-55 185.3 0.1 1.6 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 KXG54316.1 - 6.9e-31 107.2 0.0 2.9e-30 105.2 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KXG54316.1 - 4.2e-29 101.9 0.0 8.9e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.20 KXG54316.1 - 0.063 13.4 0.0 0.19 11.8 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.21 KXG54317.1 - 5.9e-33 112.5 0.8 6.8e-33 112.3 0.8 1.0 1 0 0 1 1 1 1 Synaptobrevin Prominin PF05478.11 KXG54317.1 - 0.028 12.4 0.1 0.035 12.1 0.1 1.1 1 0 0 1 1 1 0 Prominin OapA_N PF08525.11 KXG54317.1 - 3.1 7.8 6.7 4.6 7.3 6.7 1.2 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif FSH1 PF03959.13 KXG54318.1 - 3.2e-36 125.0 0.0 3.9e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXG54318.1 - 2.2e-05 25.2 0.0 3.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXG54318.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF3089 PF11288.8 KXG54318.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) adh_short PF00106.25 KXG54319.1 - 7.5e-24 84.3 0.0 5.9e-18 65.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXG54319.1 - 1.6e-09 37.7 0.0 9.5e-09 35.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG54319.1 - 1.5e-08 34.8 0.0 2.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXG54319.1 - 0.0015 17.7 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXG54319.1 - 0.014 14.9 0.0 0.078 12.4 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KXG54319.1 - 0.093 12.8 0.0 0.49 10.4 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAC PF01849.18 KXG54320.1 - 4.9e-24 84.1 0.1 2.8e-23 81.7 0.1 2.2 2 0 0 2 2 2 1 NAC domain Epimerase PF01370.21 KXG54320.1 - 3.2e-23 82.4 0.1 1e-22 80.8 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXG54320.1 - 2.7e-12 46.7 0.0 7.4e-12 45.3 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXG54320.1 - 3.7e-11 42.6 0.0 7.2e-11 41.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXG54320.1 - 1.8e-08 34.5 0.0 5e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXG54320.1 - 2.5e-05 23.6 0.0 8.2e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXG54320.1 - 0.00028 20.1 0.0 0.00047 19.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXG54320.1 - 0.00029 20.1 0.0 0.075 12.2 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KXG54320.1 - 0.024 14.2 0.1 0.15 11.6 0.1 2.2 2 0 0 2 2 2 0 NmrA-like family MAGI_u1 PF16663.5 KXG54320.1 - 0.099 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Unstructured region on MAGI KR PF08659.10 KXG54320.1 - 0.11 12.4 0.6 3 7.7 0.2 2.7 2 1 0 3 3 3 0 KR domain Nup35_RRM PF05172.13 KXG54321.1 - 0.012 15.5 0.0 0.039 13.9 0.0 1.8 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif p450 PF00067.22 KXG54323.1 - 4.2e-38 131.3 0.0 5.4e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2970 PF11174.8 KXG54323.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Hydantoinase_B PF02538.14 KXG54324.1 - 3.4e-198 659.2 0.6 4.6e-198 658.8 0.6 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXG54324.1 - 6.6e-105 350.5 0.3 2.5e-104 348.6 0.1 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXG54324.1 - 1.3e-61 207.4 1.5 6.3e-60 201.9 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.9 KXG54324.1 - 0.013 15.2 0.1 0.051 13.3 0.0 2.0 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature MFS_1 PF07690.16 KXG54325.1 - 1.4e-34 119.6 31.0 2e-34 119.1 31.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXG54325.1 - 1e-06 28.3 8.8 1e-06 28.3 8.8 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB RPT PF13446.6 KXG54325.1 - 0.15 12.0 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein DAO PF01266.24 KXG54326.1 - 2.9e-43 148.8 0.0 3.4e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXG54326.1 - 0.00027 20.2 0.1 0.018 14.1 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KXG54326.1 - 0.00032 20.7 0.0 0.094 12.7 0.0 2.7 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXG54326.1 - 0.00034 20.8 0.0 0.0008 19.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG54326.1 - 0.00085 18.6 0.0 1.4 8.1 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXG54326.1 - 0.0028 17.7 0.0 0.02 15.0 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Fungal_trans_2 PF11951.8 KXG54327.1 - 1.6e-25 89.8 1.0 1.8e-25 89.6 1.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4145 PF13643.6 KXG54327.1 - 0.02 15.0 0.1 0.79 9.9 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4145) NAD_binding_10 PF13460.6 KXG54328.1 - 1.1e-14 54.7 0.0 1.7e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXG54328.1 - 1.5e-14 54.2 0.5 1.6e-13 50.8 0.5 2.1 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXG54328.1 - 5.1e-05 22.8 0.2 0.00014 21.4 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family CFEM PF05730.11 KXG54328.1 - 0.00021 21.3 6.7 0.00021 21.3 6.7 1.8 2 0 0 2 2 2 1 CFEM domain Semialdhyde_dh PF01118.24 KXG54328.1 - 0.0037 17.7 0.1 0.0067 16.8 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KXG54328.1 - 0.0048 17.0 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 KXG54328.1 - 0.0059 15.8 0.0 0.0096 15.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KXG54328.1 - 0.039 13.0 0.4 0.058 12.4 0.4 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXG54328.1 - 0.048 12.8 0.1 0.073 12.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.18 KXG54328.1 - 0.075 13.3 0.5 0.15 12.4 0.5 1.4 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.10 KXG54328.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 KXG54328.1 - 0.17 11.2 0.1 3.5 6.9 0.1 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Aldedh PF00171.22 KXG54329.1 - 3e-77 260.1 0.0 3.8e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAD_binding_4 PF01565.23 KXG54331.1 - 1.8e-19 69.8 2.4 4e-19 68.7 2.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXG54331.1 - 9.1e-09 35.3 0.3 1.9e-08 34.2 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like Reprolysin_4 PF13583.6 KXG54331.1 - 0.033 13.8 0.4 0.095 12.3 0.1 1.9 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like MARVEL PF01284.23 KXG54332.1 - 1.5e-06 28.3 12.1 4.4e-06 26.8 12.1 1.7 1 1 0 1 1 1 1 Membrane-associating domain RTA1 PF04479.13 KXG54333.1 - 3.3e-57 193.5 7.5 4.6e-57 193.0 7.5 1.2 1 0 0 1 1 1 1 RTA1 like protein Ion_trans PF00520.31 KXG54333.1 - 0.15 11.2 8.2 0.18 11.0 4.7 2.0 2 0 0 2 2 2 0 Ion transport protein DUF1761 PF08570.10 KXG54333.1 - 3.9 7.7 9.8 0.6 10.4 4.0 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1761) Fungal_trans_2 PF11951.8 KXG54334.1 - 4.3e-08 32.4 0.2 9e-08 31.3 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Promethin PF16015.5 KXG54335.1 - 9.8e-11 41.5 11.4 1.6e-10 40.8 11.4 1.3 1 0 0 1 1 1 1 Promethin GDI PF00996.18 KXG54336.1 - 1.5e-26 93.0 0.0 1.1e-24 86.8 0.0 2.1 1 1 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KXG54336.1 - 0.11 12.7 0.0 0.37 11.1 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pro_isomerase PF00160.21 KXG54337.1 - 2e-51 174.4 0.0 2.3e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.13 KXG54338.1 - 3.8e-61 207.1 1.6 1.3e-60 205.4 1.6 1.7 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KXG54338.1 - 3.7e-05 23.3 4.6 3.7e-05 23.3 4.6 2.1 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease CrgA PF06781.12 KXG54338.1 - 0.65 10.1 2.2 14 5.8 0.0 3.3 4 0 0 4 4 4 0 Cell division protein CrgA RNase_PH PF01138.21 KXG54339.1 - 9.3e-15 55.3 0.0 4.3e-14 53.2 0.0 2.0 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF4988 PF16378.5 KXG54339.1 - 0.17 11.5 1.6 0.29 10.8 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function NAD_binding_6 PF08030.12 KXG54340.1 - 2.5e-23 82.9 0.0 8.2e-23 81.3 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KXG54340.1 - 5.5e-18 65.3 10.2 5.5e-18 65.3 10.2 2.8 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXG54340.1 - 2e-13 50.4 0.0 6.6e-13 48.7 0.0 1.9 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXG54340.1 - 0.00032 21.3 0.0 0.071 13.8 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Peptidase_M15_2 PF05951.13 KXG54340.1 - 0.094 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Sgf11 PF08209.11 KXG54342.1 - 1.5e-06 27.6 0.8 1.5e-06 27.6 0.8 1.9 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 KXG54342.1 - 0.068 13.1 0.9 0.12 12.3 0.9 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Actin_micro PF17003.5 KXG54342.1 - 0.1 11.7 0.2 0.19 10.9 0.1 1.4 2 0 0 2 2 2 0 Putative actin-like family Neuromodulin_N PF10580.9 KXG54342.1 - 0.22 11.3 3.3 1.1 9.2 0.2 2.4 2 0 0 2 2 2 0 Gap junction protein N-terminal region zf-C2H2_4 PF13894.6 KXG54342.1 - 1.1 10.3 3.7 1 10.3 0.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC5 PF06221.13 KXG54343.1 - 1.1e-21 76.5 4.6 1.7e-21 75.9 4.6 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type p450 PF00067.22 KXG54344.1 - 1.1e-64 219.0 0.0 2.2e-64 217.9 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 Mpv17_PMP22 PF04117.12 KXG54344.1 - 1.4e-08 34.8 0.1 5.3e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family Sdh_cyt PF01127.22 KXG54344.1 - 0.32 11.0 3.9 0.21 11.6 0.7 2.1 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit MFS_1 PF07690.16 KXG54345.1 - 4.1e-41 141.1 49.9 4.1e-41 141.1 49.9 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily EbsA PF17255.2 KXG54345.1 - 0.76 10.1 2.7 50 4.2 0.0 2.6 2 0 0 2 2 2 0 EbsA-like protein Aldo_ket_red PF00248.21 KXG54346.1 - 3.2e-72 243.2 0.0 3.9e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hexokinase_2 PF03727.16 KXG54347.1 - 1.1e-78 264.0 0.0 1.4e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXG54347.1 - 5.9e-70 235.2 0.0 9e-70 234.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DUF1690 PF07956.11 KXG54348.1 - 9.9e-39 132.9 5.0 2.4e-18 66.9 2.7 2.0 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) CBP4 PF07960.11 KXG54348.1 - 0.081 12.8 1.1 0.11 12.3 1.1 1.5 1 1 0 1 1 1 0 CBP4 Matrilin_ccoil PF10393.9 KXG54348.1 - 0.25 11.2 2.7 4.9 7.1 1.1 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Apolipoprotein PF01442.18 KXG54348.1 - 0.54 10.1 9.2 2.5 7.9 4.5 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain POP1 PF06978.11 KXG54349.1 - 5.5e-74 248.6 19.4 9.7e-74 247.8 19.4 1.4 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KXG54349.1 - 3.7e-31 107.3 0.5 1.2e-30 105.6 0.5 2.0 1 0 0 1 1 1 1 POPLD (NUC188) domain A_deamin PF02137.18 KXG54349.1 - 0.058 12.8 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain DSPc PF00782.20 KXG54350.1 - 8.9e-16 57.9 0.0 1.2e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXG54350.1 - 0.051 13.1 0.0 0.092 12.3 0.0 1.4 1 1 0 1 1 1 0 Protein-tyrosine phosphatase TPMT PF05724.11 KXG54351.1 - 3.2e-23 82.6 0.0 2.5e-21 76.4 0.0 2.2 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.6 KXG54351.1 - 0.0018 18.1 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG54351.1 - 0.0028 18.3 0.0 0.0051 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXG54351.1 - 0.011 16.3 0.0 0.02 15.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KXG54351.1 - 0.037 13.9 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain N2227 PF07942.12 KXG54351.1 - 0.076 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein AdoMet_MTase PF07757.13 KXG54351.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Aminotran_5 PF00266.19 KXG54352.1 - 3.4e-18 65.8 0.0 7.1e-09 35.1 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V MOSC_N PF03476.16 KXG54352.1 - 1.5e-16 60.3 0.0 3.3e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain NmrA PF05368.13 KXG54353.1 - 5.6e-44 150.4 0.1 6.6e-44 150.2 0.1 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXG54353.1 - 3.8e-08 33.4 0.0 5.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXG54353.1 - 0.00017 21.2 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXG54353.1 - 0.034 13.1 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RsbRD_N PF14361.6 KXG54353.1 - 0.11 13.1 0.0 0.28 11.9 0.0 1.6 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain M_domain PF12938.7 KXG54354.1 - 0.06 13.1 7.5 0.098 12.4 7.5 1.4 1 0 0 1 1 1 0 M domain of GW182 SKG6 PF08693.10 KXG54354.1 - 0.1 12.0 1.9 0.24 10.8 1.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Alpha_GJ PF03229.13 KXG54354.1 - 0.15 12.6 5.1 0.6 10.7 5.2 2.1 1 1 0 1 1 1 0 Alphavirus glycoprotein J TRI12 PF06609.13 KXG54355.1 - 1.7e-36 125.8 27.8 2.1e-36 125.6 27.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXG54355.1 - 5.2e-18 65.1 51.7 5.2e-18 65.1 51.7 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXG54355.1 - 8.7e-12 44.6 6.3 8.7e-12 44.6 6.3 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter UCH PF00443.29 KXG54356.1 - 5.1e-53 180.2 0.1 7.2e-53 179.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KXG54356.1 - 2.3e-12 46.5 0.0 9e-12 44.6 0.0 2.1 1 0 0 1 1 1 1 Ubiquitin family UCH_1 PF13423.6 KXG54356.1 - 1.4e-09 38.0 13.9 1.2e-08 35.0 13.9 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase 4HBT PF03061.22 KXG54356.1 - 1.7e-05 25.1 0.1 3.1e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily ARPC4 PF05856.12 KXG54357.1 - 1.4e-75 252.5 4.0 1.6e-75 252.3 4.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) RRM_1 PF00076.22 KXG54358.1 - 0.00068 19.4 0.2 0.014 15.2 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2461 PF09365.10 KXG54359.1 - 9.5e-54 182.5 0.0 7.5e-30 104.4 0.1 2.2 2 0 0 2 2 2 2 Conserved hypothetical protein (DUF2461) Zn_clus PF00172.18 KXG54360.1 - 1.1e-08 35.1 6.9 1.5e-08 34.6 6.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KXG54361.1 - 8.3e-66 222.1 0.0 8.5e-65 218.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 KXG54361.1 - 3e-38 130.1 0.4 6.6e-38 129.1 0.4 1.6 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 KXG54361.1 - 2.9e-35 121.8 0.0 2.1e-33 115.7 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXG54361.1 - 9.5e-05 21.5 0.0 0.00019 20.5 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXG54361.1 - 0.00026 21.0 0.1 0.0082 16.1 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXG54361.1 - 0.00076 18.9 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXG54361.1 - 0.0033 16.8 0.0 0.0064 15.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 KXG54361.1 - 0.012 15.2 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1348 PF07080.11 KXG54362.1 - 3e-56 188.9 3.7 3.2e-56 188.8 3.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KXG54362.1 - 6.8e-05 23.5 0.7 8.6e-05 23.1 0.7 1.3 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXG54362.1 - 7.8e-05 23.0 0.1 0.00011 22.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Amidohydro_1 PF01979.20 KXG54364.1 - 0.61 9.3 5.7 0.66 9.2 3.8 2.1 2 0 0 2 2 2 0 Amidohydrolase family Carbam_trans_N PF02543.15 KXG54364.1 - 1.2 8.7 4.2 2.3 7.8 4.2 1.4 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus zf-Di19 PF05605.12 KXG54364.1 - 2.1 8.7 3.7 46 4.4 0.2 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF5333 PF17267.2 KXG54364.1 - 3.6 7.8 11.5 0.085 13.1 3.0 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5333) P5CR_dimer PF14748.6 KXG54365.1 - 1.6e-30 105.4 2.3 3.2e-30 104.4 1.2 2.0 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KXG54365.1 - 2.7e-13 50.3 0.2 7.1e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent BacteriocIIc_cy PF12173.8 KXG54365.1 - 0.82 10.0 3.3 0.88 9.9 0.3 2.2 2 0 0 2 2 2 0 Bacteriocin class IIc cyclic gassericin A-like Nitroreductase PF00881.24 KXG54366.1 - 0.0023 18.0 0.1 0.0054 16.8 0.1 1.6 1 0 0 1 1 1 1 Nitroreductase family Redoxin PF08534.10 KXG54367.1 - 3.7e-36 124.1 0.0 4.1e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXG54367.1 - 3.7e-13 49.5 0.0 4.6e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family WD40 PF00400.32 KXG54368.1 - 3.8e-08 33.9 15.7 0.0051 17.6 0.1 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KXG54368.1 - 1.8e-06 27.4 17.3 1.8e-06 27.4 17.3 2.5 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KXG54368.1 - 0.062 13.2 3.0 0.2 11.6 3.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 KXG54368.1 - 0.19 12.2 4.4 0.38 11.2 4.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain XAF1_C PF18608.1 KXG54368.1 - 2.4 7.8 5.4 1.4 8.5 0.3 2.6 2 0 0 2 2 2 0 XIAP-associated factor 1 C-terminal domain UQ_con PF00179.26 KXG54369.1 - 4.4e-47 159.2 0.0 5e-47 159.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXG54369.1 - 0.0003 20.5 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KXG54369.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 KXG54369.1 - 0.15 12.4 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain Ribosomal_L24e PF01246.20 KXG54370.1 - 1.6e-21 76.3 6.5 7.4e-18 64.5 0.9 2.7 3 0 0 3 3 3 2 Ribosomal protein L24e Acetyltransf_1 PF00583.25 KXG54371.1 - 5.3e-10 39.6 0.1 6.9e-10 39.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXG54371.1 - 3.8e-08 33.3 0.0 5.4e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXG54371.1 - 6.1e-07 29.8 0.3 8.6e-07 29.3 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Lyase_1 PF00206.20 KXG54372.1 - 6.2e-111 370.7 0.0 1e-110 370.1 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KXG54372.1 - 2.6e-20 72.6 0.0 6.9e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus Abhydrolase_3 PF07859.13 KXG54373.1 - 7e-53 179.6 0.0 9.8e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXG54373.1 - 0.00065 19.2 0.0 0.1 12.0 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Aminotran_1_2 PF00155.21 KXG54374.1 - 2.7e-75 253.8 0.0 3.1e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II rve PF00665.26 KXG54375.1 - 8.8e-05 22.7 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain fn3_2 PF16893.5 KXG54376.1 - 2.8e-38 129.9 0.0 5e-38 129.1 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KXG54376.1 - 5.9e-25 87.0 0.4 1e-24 86.2 0.4 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 KXG54376.1 - 3.5e-13 49.3 0.0 6e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KXG54376.1 - 1e-07 32.2 0.0 1.8e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 KXG54376.1 - 2.2e-05 24.6 0.0 5.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.21 KXG54376.1 - 0.001 19.4 0.0 0.0036 17.6 0.0 1.9 1 1 0 1 1 1 1 Fibronectin type III domain BRCT_2 PF16589.5 KXG54376.1 - 0.0057 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain eIF-1a PF01176.19 KXG54377.1 - 4.2e-22 77.7 0.0 5.9e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF3124 PF11322.8 KXG54377.1 - 0.086 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) Peptidase_S41 PF03572.18 KXG54378.1 - 1e-07 31.6 0.0 2.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 DUF397 PF04149.12 KXG54378.1 - 0.054 13.6 0.2 0.96 9.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF397) ERCC4 PF02732.15 KXG54379.1 - 6.4e-18 65.4 0.1 6.1e-17 62.3 0.0 2.7 3 0 0 3 3 3 1 ERCC4 domain HHH_5 PF14520.6 KXG54379.1 - 0.026 15.1 0.0 0.079 13.6 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain 30K_MP_core PF17644.1 KXG54380.1 - 0.047 13.6 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Core domain of 30K viral movement proteins gag-asp_proteas PF13975.6 KXG54380.1 - 0.16 12.6 0.0 0.32 11.6 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease WH1 PF00568.23 KXG54382.1 - 6.6e-29 100.1 0.0 1.2e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 KXG54382.1 - 0.011 15.6 0.3 0.029 14.2 0.3 1.7 1 0 0 1 1 1 0 WH2 motif ChuX_HutX PF06228.13 KXG54382.1 - 0.087 12.6 0.0 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 Haem utilisation ChuX/HutX CorA PF01544.18 KXG54383.1 - 3.4e-08 33.2 0.0 5.6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ApoL PF05461.11 KXG54383.1 - 0.022 14.1 0.6 0.022 14.1 0.6 1.7 2 0 0 2 2 2 0 Apolipoprotein L AdoMet_MTase PF07757.13 KXG54384.1 - 1.4e-24 86.6 0.0 2.2e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase His_Phos_1 PF00300.22 KXG54385.1 - 5.5e-38 130.6 0.8 5.5e-21 75.1 0.3 2.3 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DASH_Hsk3 PF08227.11 KXG54386.1 - 7.6e-22 77.4 3.1 1e-21 77.0 3.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like BBS2_C PF14782.6 KXG54386.1 - 0.11 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal ApbA PF02558.16 KXG54387.1 - 1.4e-25 89.7 0.0 2.2e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXG54387.1 - 3.2e-20 72.6 0.1 1.1e-19 70.9 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal APH PF01636.23 KXG54388.1 - 1.5e-06 28.3 0.9 0.039 13.9 0.3 2.3 2 1 0 2 2 2 2 Phosphotransferase enzyme family DEAD PF00270.29 KXG54389.1 - 2.3e-36 125.2 0.2 5.4e-36 124.0 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG54389.1 - 4.4e-27 94.6 0.1 8.8e-25 87.2 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KXG54389.1 - 2.2e-08 34.3 0.0 5.3e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rpr2 PF04032.16 KXG54390.1 - 4.1e-26 91.1 2.5 8.6e-26 90.1 2.5 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF1664 PF07889.12 KXG54391.1 - 0.0013 18.8 0.9 0.0034 17.4 0.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KXG54391.1 - 0.0027 17.9 1.8 0.0072 16.5 1.8 1.6 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family Fzo_mitofusin PF04799.13 KXG54391.1 - 0.003 17.1 0.3 0.0047 16.5 0.3 1.3 1 0 0 1 1 1 1 fzo-like conserved region PhaP_Bmeg PF09602.10 KXG54391.1 - 0.0092 15.9 0.1 0.015 15.3 0.1 1.3 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Baculo_PEP_C PF04513.12 KXG54391.1 - 0.029 14.4 0.3 2.5 8.1 0.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cobalamin_bind PF01122.19 KXG54391.1 - 0.034 13.1 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic cobalamin-binding protein DUF4407 PF14362.6 KXG54391.1 - 0.05 13.0 2.1 0.055 12.8 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSCB_C PF07743.13 KXG54391.1 - 0.064 13.8 0.9 1.7 9.2 0.1 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Wbp11 PF09429.10 KXG54392.1 - 3.8e-21 75.3 14.6 3.8e-21 75.3 14.6 2.5 3 1 0 3 3 3 1 WW domain binding protein 11 Pkinase PF00069.25 KXG54393.1 - 1.6e-53 181.8 5.1 1.5e-34 119.5 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXG54393.1 - 3.1e-36 125.0 0.0 8.2e-26 90.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXG54393.1 - 0.012 14.9 0.3 0.033 13.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KXG54393.1 - 0.032 14.1 1.5 0.85 9.5 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Terminase_6C PF17289.2 KXG54393.1 - 0.2 11.8 0.7 0.43 10.7 0.7 1.5 1 0 0 1 1 1 0 Terminase RNaseH-like domain DUF3896 PF13035.6 KXG54393.1 - 1.9 8.7 6.0 0.5 10.6 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3896) BTB PF00651.31 KXG54394.1 - 1.2e-26 93.1 0.0 4.6e-13 49.4 0.4 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.6 KXG54394.1 - 3.3e-07 30.5 0.1 2.4e-06 27.7 0.1 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXG54394.1 - 5.9e-07 30.0 0.1 1.2e-06 29.0 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG54394.1 - 2e-06 28.2 0.0 5e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KXG54394.1 - 0.00025 21.3 0.0 0.018 15.5 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KXG54394.1 - 0.023 15.2 0.1 0.25 12.0 0.1 2.7 2 0 0 2 2 2 0 Ankyrin repeat DUF3342 PF11822.8 KXG54394.1 - 0.11 12.7 0.1 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) SMC_N PF02463.19 KXG54395.1 - 5.3e-19 68.5 10.0 4.3e-18 65.6 10.0 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXG54395.1 - 9.1e-12 45.9 66.2 1.3e-11 45.4 23.0 4.8 2 2 0 3 3 3 1 AAA domain AAA_15 PF13175.6 KXG54395.1 - 3e-05 23.9 1.0 3e-05 23.9 1.0 3.5 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KXG54395.1 - 0.00039 20.1 0.0 0.00076 19.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KXG54395.1 - 0.00083 19.2 6.7 0.035 13.9 0.1 3.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KXG54395.1 - 0.065 12.8 0.0 0.31 10.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXG54395.1 - 0.069 13.7 0.0 0.069 13.7 0.0 4.9 3 2 0 3 3 3 0 ABC transporter DUF3287 PF11690.8 KXG54395.1 - 2 8.2 8.1 0.39 10.4 1.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) zf-C2H2 PF00096.26 KXG54396.1 - 2.2e-06 27.8 18.7 0.0035 17.7 3.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXG54396.1 - 0.00065 20.0 1.6 0.00065 20.0 1.6 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXG54396.1 - 0.32 12.0 21.6 0.46 11.5 2.7 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 KXG54396.1 - 0.33 11.4 4.5 0.93 10.0 2.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.15 KXG54396.1 - 9.1 6.4 13.1 2 8.5 4.4 2.6 1 1 1 2 2 2 0 BED zinc finger FMN_dh PF01070.18 KXG54397.1 - 4.9e-121 404.0 0.0 8.5e-121 403.2 0.0 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Lipase_3 PF01764.25 KXG54397.1 - 1.7e-14 53.9 0.0 3.8e-11 43.0 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) NMO PF03060.15 KXG54397.1 - 1.5e-05 24.6 0.2 2.8e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KXG54397.1 - 0.00038 19.8 0.1 0.2 10.9 0.2 2.8 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 KXG54397.1 - 0.0045 16.0 0.1 0.0086 15.1 0.1 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXG54397.1 - 0.0062 15.7 0.1 0.01 15.0 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Abhydrolase_6 PF12697.7 KXG54397.1 - 0.0099 16.5 3.7 0.013 16.1 1.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXG54397.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 WD40 PF00400.32 KXG54398.1 - 6.4e-64 210.4 21.3 1.8e-11 44.4 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG54398.1 - 1.8e-27 95.5 1.0 7.7e-06 26.1 0.0 6.1 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXG54398.1 - 1.1e-13 50.9 0.2 0.062 12.3 0.0 5.9 1 1 5 6 6 6 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXG54398.1 - 1.6e-07 31.1 0.1 0.068 13.1 0.0 5.6 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Ret2_MD PF18528.1 KXG54398.1 - 4.3e-05 23.8 0.0 0.4 11.1 0.0 4.3 2 1 3 5 5 5 1 RNA editing 3' terminal uridylyl transferase 2 middle domain Gmad1 PF10647.9 KXG54398.1 - 0.00016 21.5 1.7 0.029 14.1 0.1 3.1 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KXG54398.1 - 0.00056 18.7 9.7 0.52 8.9 0.0 4.3 3 1 2 5 5 5 2 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 KXG54398.1 - 0.00065 19.3 0.3 3.9 7.3 0.0 4.2 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.11 KXG54398.1 - 0.0026 16.6 0.5 0.19 10.4 0.1 2.8 1 1 0 2 2 2 1 Nup133 N terminal like DUF5570 PF17731.1 KXG54398.1 - 0.0036 17.4 5.3 0.87 9.7 0.1 3.7 3 1 2 5 5 5 2 Family of unknown function (DUF5570) SH3_3 PF08239.11 KXG54398.1 - 0.025 14.9 0.9 20 5.6 0.1 3.5 3 0 0 3 3 3 0 Bacterial SH3 domain DUF3748 PF12566.8 KXG54398.1 - 0.029 14.3 2.2 18 5.3 0.0 4.3 3 2 3 6 6 6 0 Protein of unknown function (DUF3748) TruB_C PF09142.11 KXG54398.1 - 0.035 13.9 0.0 13 5.7 0.0 3.8 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal PALB2_WD40 PF16756.5 KXG54398.1 - 0.12 11.2 1.1 7.5 5.4 0.0 2.8 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain DUF4082 PF13313.6 KXG54398.1 - 0.14 12.2 2.5 6 6.9 0.0 3.8 1 1 2 4 4 4 0 Domain of unknown function (DUF4082) WD40_like PF17005.5 KXG54398.1 - 0.19 11.0 0.0 25 4.1 0.0 3.2 3 1 1 4 4 4 0 WD40-like domain MFS_1 PF07690.16 KXG54399.1 - 1.7e-33 116.0 25.8 1.7e-33 116.0 25.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3482 PF11981.8 KXG54399.1 - 0.17 11.3 1.4 5.7 6.2 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3482) Phage_holin_2_1 PF04971.12 KXG54399.1 - 1.8 8.6 9.8 0.53 10.3 0.1 3.2 2 1 1 3 3 3 0 Bacteriophage P21 holin S p450 PF00067.22 KXG54401.1 - 1.4e-38 132.9 0.0 2.7e-38 131.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 SQHop_cyclase_N PF13249.6 KXG54402.1 - 1.7e-116 388.4 0.1 1.6e-104 349.1 0.0 5.0 3 2 1 5 5 5 4 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KXG54402.1 - 1.4e-115 385.8 1.9 1.2e-108 363.0 0.4 3.2 3 0 0 3 3 3 3 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KXG54402.1 - 1.7e-30 104.5 15.6 3.1e-08 33.2 0.1 8.2 8 0 0 8 8 8 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KXG54402.1 - 0.00028 20.0 0.6 6.5 5.7 0.0 5.1 4 2 2 6 6 6 3 A-macroglobulin TED domain Pec_lyase PF09492.10 KXG54402.1 - 0.0011 18.3 1.4 8.1 5.7 0.0 4.8 5 1 0 5 5 5 1 Pectic acid lyase Transferase PF02458.15 KXG54403.1 - 0.014 14.1 0.0 0.056 12.1 0.0 1.7 2 0 0 2 2 2 0 Transferase family Ank_4 PF13637.6 KXG54404.1 - 1.1e-60 201.2 5.3 4.7e-08 33.4 0.0 10.2 7 3 3 10 10 10 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXG54404.1 - 3.7e-56 187.7 0.3 7e-14 52.2 0.0 6.6 3 3 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXG54404.1 - 4.5e-47 152.6 5.2 0.0024 18.2 0.0 13.4 13 0 0 13 13 13 11 Ankyrin repeat Ank PF00023.30 KXG54404.1 - 8.2e-45 149.4 4.9 0.00086 19.7 0.0 13.1 13 0 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.6 KXG54404.1 - 8.1e-42 140.7 13.5 1.4e-07 31.6 0.1 9.0 6 3 3 9 9 9 8 Ankyrin repeats (many copies) CCDC142 PF14923.6 KXG54404.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil protein 142 DUF604 PF04646.12 KXG54405.1 - 1.4e-06 27.9 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 KXG54405.1 - 0.00066 19.2 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Fringe-like SRF-TF PF00319.18 KXG54406.1 - 3.1e-21 74.6 0.1 4.7e-21 74.0 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Mg_trans_NIPA PF05653.14 KXG54407.1 - 2.9e-14 52.9 6.0 5.2e-14 52.0 6.0 1.4 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXG54407.1 - 1.2e-05 25.5 0.6 1.2e-05 25.5 0.6 2.4 2 0 0 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 KXG54407.1 - 2.4e-05 23.7 0.1 2.4e-05 23.7 0.1 1.9 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport 7TMR-DISM_7TM PF07695.11 KXG54407.1 - 0.001 19.0 10.6 0.086 12.7 0.2 2.4 2 0 0 2 2 2 2 7TM diverse intracellular signalling Multi_Drug_Res PF00893.19 KXG54407.1 - 3.3 8.4 7.3 17 6.2 0.3 2.7 2 1 0 2 2 2 0 Small Multidrug Resistance protein vATP-synt_E PF01991.18 KXG54408.1 - 4.2e-62 209.1 7.7 4.8e-62 208.9 7.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4288 PF14119.6 KXG54408.1 - 1.3 9.4 6.4 14 6.1 0.6 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4288) PhoLip_ATPase_C PF16212.5 KXG54410.1 - 1.5e-80 270.5 25.1 1.5e-80 270.5 25.1 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXG54410.1 - 7.3e-19 67.2 1.1 7.3e-19 67.2 1.1 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KXG54410.1 - 3.1e-12 46.4 0.0 1.3e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXG54410.1 - 2.4e-09 37.8 5.2 5.5e-06 26.8 0.6 3.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXG54410.1 - 0.0059 16.2 1.3 0.037 13.5 0.0 2.7 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXG54410.1 - 0.011 15.4 0.6 0.034 13.9 0.6 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SEN1_N PF12726.7 KXG54411.1 - 5e-209 696.3 1.9 6.6e-209 695.9 1.9 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KXG54411.1 - 6.9e-75 252.2 0.9 6.9e-75 252.2 0.9 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KXG54411.1 - 6.6e-61 205.4 0.0 1.3e-60 204.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXG54411.1 - 2.3e-09 37.2 0.2 2.5e-05 24.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KXG54411.1 - 4e-08 33.7 0.0 1.2e-07 32.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXG54411.1 - 1.6e-06 28.0 0.2 0.03 14.0 0.1 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KXG54411.1 - 6.4e-06 25.9 0.1 0.00024 20.7 0.1 2.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KXG54411.1 - 0.0053 16.0 0.4 0.14 11.4 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 KXG54411.1 - 0.013 15.3 0.5 0.031 14.0 0.1 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase T2SSE PF00437.20 KXG54411.1 - 0.014 14.5 0.0 0.03 13.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4164 PF13747.6 KXG54411.1 - 0.03 14.6 2.9 0.14 12.5 2.9 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) TPR_MLP1_2 PF07926.12 KXG54411.1 - 0.036 14.1 0.2 0.14 12.2 0.2 2.0 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA PF00004.29 KXG54411.1 - 0.055 13.9 0.0 0.18 12.3 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KXG54411.1 - 0.068 13.2 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-CCHC_3 PF13917.6 KXG54411.1 - 1.7 8.7 19.9 0.34 10.9 0.4 3.7 1 1 2 3 3 3 0 Zinc knuckle Transp_cyt_pur PF02133.15 KXG54412.1 - 8.1e-84 281.9 39.3 9.5e-84 281.7 39.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pyrid_oxidase_2 PF13883.6 KXG54413.1 - 1.7e-33 116.0 0.0 2.3e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cyclin PF08613.11 KXG54414.1 - 1.8e-05 25.1 0.0 1.8e-05 25.1 0.0 2.2 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 KXG54414.1 - 0.012 15.4 0.1 0.024 14.4 0.1 1.6 1 1 0 1 1 1 0 Cyclin, N-terminal domain Aminotran_5 PF00266.19 KXG54415.1 - 1.5e-54 185.4 0.0 2.3e-54 184.8 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXG54415.1 - 3.8e-05 22.4 0.0 6.5e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXG54415.1 - 0.0011 18.2 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Robl_LC7 PF03259.17 KXG54416.1 - 9e-09 35.0 0.5 0.01 15.6 0.0 3.1 3 0 0 3 3 3 3 Roadblock/LC7 domain Ipi1_N PF12333.8 KXG54418.1 - 5.3e-27 94.4 0.4 2.2e-26 92.4 0.0 2.1 2 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.6 KXG54418.1 - 0.002 18.6 0.6 0.81 10.3 0.3 2.5 1 1 1 2 2 2 2 HEAT-like repeat Biliv-reduc_cat PF09166.10 KXG54418.1 - 0.16 12.3 0.1 23 5.3 0.1 2.5 2 0 0 2 2 2 0 Biliverdin reductase, catalytic GATA PF00320.27 KXG54419.1 - 1.6e-16 59.6 2.3 3.2e-16 58.6 2.3 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KXG54419.1 - 7.9e-13 48.0 2.4 1.6e-12 47.0 2.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AreA_N PF07573.11 KXG54419.1 - 3e-12 47.0 4.1 3e-12 47.0 4.1 3.5 3 1 0 3 3 3 1 Nitrogen regulatory protein AreA N terminus DLH PF01738.18 KXG54422.1 - 7.9e-16 58.3 0.0 9.5e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family zf-C2H2 PF00096.26 KXG54423.1 - 7.9e-12 45.0 11.0 6.9e-06 26.2 0.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXG54423.1 - 2.4e-09 37.3 9.2 0.0002 21.9 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXG54423.1 - 1.4e-08 34.8 9.6 4.8e-06 26.7 2.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KXG54423.1 - 4.4e-05 23.1 7.8 0.0067 16.2 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KXG54423.1 - 0.0021 18.3 7.1 0.0066 16.7 0.1 2.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXG54423.1 - 0.013 15.4 8.5 0.36 10.9 0.5 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HE PF16278.5 KXG54423.1 - 0.043 14.3 7.4 1.3 9.6 1.2 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KXG54423.1 - 0.3 11.6 0.2 0.3 11.6 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KXG54423.1 - 0.4 10.5 3.6 5.2 6.9 0.3 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-CHY PF05495.12 KXG54423.1 - 0.71 10.4 3.6 2.5 8.7 3.8 1.7 1 1 0 1 1 1 0 CHY zinc finger zf-AN1 PF01428.16 KXG54423.1 - 4.4 7.6 8.3 17 5.6 1.8 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger Pyr_redox_3 PF13738.6 KXG54425.1 - 3e-14 53.0 0.0 1.4e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXG54425.1 - 3e-13 49.1 0.0 5.3e-12 44.9 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXG54425.1 - 1.7e-11 43.9 0.0 1.5e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXG54425.1 - 2.1e-09 37.0 0.1 5.1e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXG54425.1 - 1.7e-06 28.1 0.3 4.4e-06 26.8 0.1 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXG54425.1 - 0.00015 21.1 0.4 0.0003 20.1 0.1 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KXG54425.1 - 0.0018 18.3 0.7 0.042 13.9 0.2 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KXG54425.1 - 0.0032 16.2 0.8 0.86 8.2 0.1 2.8 3 0 0 3 3 3 2 HI0933-like protein Lycopene_cycl PF05834.12 KXG54425.1 - 0.029 13.4 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 KXG54425.1 - 0.058 12.7 0.4 0.92 8.8 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXG54425.1 - 0.13 11.3 0.2 0.3 10.1 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 KXG54425.1 - 0.17 11.5 0.2 2.9 7.4 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF1075 PF06388.11 KXG54426.1 - 0.15 12.1 0.2 0.46 10.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) MFS_1 PF07690.16 KXG54427.1 - 1.3e-30 106.5 35.9 3.6e-30 105.1 35.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXG54427.1 - 4.2e-05 23.0 18.5 0.00057 19.3 7.2 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Orf78 PF06024.12 KXG54427.1 - 0.055 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Orf78 (ac78) DUF2834 PF11196.8 KXG54427.1 - 8.1 6.9 10.5 1.3 9.4 0.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2834) ADH_N PF08240.12 KXG54428.1 - 1.8e-19 69.6 1.8 3.2e-19 68.8 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG54428.1 - 2.4e-17 63.1 0.0 4.5e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXG54428.1 - 0.00021 20.7 0.2 0.00034 20.0 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXG54428.1 - 0.00049 19.5 0.1 0.001 18.4 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KXG54428.1 - 0.042 14.0 0.1 0.076 13.2 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 KXG54428.1 - 0.056 12.8 0.3 0.083 12.2 0.3 1.2 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.18 KXG54428.1 - 0.073 12.9 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.25 KXG54429.1 - 1.2e-14 54.4 0.0 2e-13 50.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG54429.1 - 4.2e-09 36.1 0.0 1.5e-07 30.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase FAD_binding_2 PF00890.24 KXG54430.1 - 2.6e-35 122.3 2.4 6.7e-34 117.7 2.4 2.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXG54430.1 - 8.9e-11 42.0 0.1 1.4e-09 38.1 0.0 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXG54430.1 - 7.5e-10 38.7 0.0 1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG54430.1 - 2.7e-09 37.1 0.1 1e-08 35.3 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG54430.1 - 7.2e-07 28.7 0.0 2e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG54430.1 - 3e-05 23.4 0.8 0.0004 19.7 0.8 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KXG54430.1 - 5.5e-05 22.1 2.6 0.00016 20.6 2.6 1.9 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KXG54430.1 - 0.0022 18.5 1.0 0.0047 17.4 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXG54430.1 - 0.0029 16.9 0.2 0.0051 16.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXG54430.1 - 0.0087 15.3 1.0 0.054 12.7 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXG54430.1 - 0.012 14.8 2.5 0.012 14.8 2.5 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXG54430.1 - 0.025 13.9 1.2 0.056 12.7 1.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 KXG54430.1 - 0.14 11.4 0.1 1.3 8.2 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AP_endonuc_2 PF01261.24 KXG54431.1 - 4.8e-21 75.2 0.0 6.9e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Oxidored_FMN PF00724.20 KXG54432.1 - 8.2e-48 163.4 0.0 1.9e-46 158.9 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Shikimate_dh_N PF08501.11 KXG54433.1 - 1.1e-14 54.4 0.0 2.1e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain GFO_IDH_MocA PF01408.22 KXG54434.1 - 1.9e-18 67.4 0.0 3.8e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXG54434.1 - 5.9e-12 45.6 0.0 9.4e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain G6PD_N PF00479.22 KXG54434.1 - 0.25 12.0 0.0 0.42 11.2 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain AP_endonuc_2 PF01261.24 KXG54435.1 - 8.6e-10 38.4 0.0 1.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel CoA_transf_3 PF02515.17 KXG54436.1 - 1e-62 212.4 0.0 1.5e-62 211.9 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III AMP-binding PF00501.28 KXG54437.1 - 9.5e-79 265.0 0.0 1.2e-78 264.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG54437.1 - 7.9e-14 52.4 0.2 4.6e-13 49.9 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 4HBT_3 PF13622.6 KXG54438.1 - 3.7e-65 220.6 0.3 9.2e-65 219.3 0.3 1.6 1 0 0 1 1 1 1 Thioesterase-like superfamily Chromate_transp PF02417.15 KXG54438.1 - 1.2e-59 201.0 25.2 6.2e-35 120.7 12.1 2.5 2 0 0 2 2 2 2 Chromate transporter Acyl_CoA_thio PF02551.15 KXG54438.1 - 6.8e-18 64.8 0.0 1.9e-08 34.2 0.0 3.5 3 1 0 3 3 3 3 Acyl-CoA thioesterase Redoxin PF08534.10 KXG54439.1 - 1.3e-37 128.7 0.0 1.5e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXG54439.1 - 6.2e-14 52.0 0.0 7.9e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF3669 PF12417.8 KXG54442.1 - 4.1e-15 55.7 0.3 1.3e-14 54.2 0.3 1.9 1 0 0 1 1 1 1 Zinc finger protein UBA2_C PF16195.5 KXG54442.1 - 0.15 12.8 0.3 0.27 12.0 0.3 1.3 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Sugar_tr PF00083.24 KXG54443.1 - 2.3e-107 359.7 20.4 2.8e-107 359.4 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG54443.1 - 2e-22 79.6 33.1 5.5e-22 78.2 24.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM151 PF14857.6 KXG54443.1 - 0.029 13.3 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 TMEM151 family TMEM132D_C PF15706.5 KXG54443.1 - 0.28 11.0 0.7 0.75 9.6 0.7 1.7 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term His_Phos_1 PF00300.22 KXG54444.1 - 0.05 13.3 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) FMO-like PF00743.19 KXG54445.1 - 4.3e-29 101.3 0.0 7.2e-10 37.9 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXG54445.1 - 8.2e-15 54.8 0.0 3.7e-09 36.3 0.0 3.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG54445.1 - 8.4e-11 41.6 0.0 1.9e-09 37.2 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG54445.1 - 6.2e-09 36.0 0.1 0.00059 19.9 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXG54445.1 - 1.4e-06 27.7 0.4 0.011 14.9 0.0 3.8 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXG54445.1 - 2.1e-05 24.7 0.0 5.6e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXG54445.1 - 0.00058 19.5 0.4 2 7.9 0.0 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXG54445.1 - 0.0059 17.1 0.5 2.9 8.5 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXG54445.1 - 0.01 15.1 0.2 0.048 12.9 0.0 1.9 2 0 0 2 2 2 0 Thi4 family PdxA PF04166.12 KXG54445.1 - 0.025 14.0 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA Amino_oxidase PF01593.24 KXG54445.1 - 0.085 12.1 0.0 6.6 5.9 0.0 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Acetyltransf_3 PF13302.7 KXG54446.1 - 1.2e-17 64.9 0.1 2.9e-17 63.6 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXG54446.1 - 2.5e-08 34.2 0.0 4.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KXG54446.1 - 2.9e-05 23.8 0.0 5.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXG54446.1 - 0.0005 20.0 0.1 0.0015 18.5 0.1 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.7 KXG54446.1 - 0.058 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DAPDH_C PF16654.5 KXG54446.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain FA_desaturase PF00487.24 KXG54447.1 - 4.7e-32 111.8 19.6 8.6e-32 111.0 19.6 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF1275 PF06912.11 KXG54448.1 - 4.2e-44 150.8 7.4 5.7e-44 150.3 7.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4603 PF15376.6 KXG54448.1 - 0.29 8.5 0.0 0.37 8.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Fungal_trans PF04082.18 KXG54449.1 - 1.3e-07 30.9 4.1 5.5e-07 28.9 4.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 KXG54450.1 - 2e-87 293.6 0.0 2.5e-87 293.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXG54450.1 - 3.5e-13 50.3 0.0 1.6e-12 48.2 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Glyco_hydro_20 PF00728.22 KXG54452.1 - 1.2e-22 80.8 0.9 1.6e-16 60.6 0.0 2.5 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Fungal_trans PF04082.18 KXG54452.1 - 5.3e-16 58.5 0.0 9.9e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_20b PF02838.15 KXG54452.1 - 5.4e-09 36.9 0.0 1.1e-08 35.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Zn_clus PF00172.18 KXG54452.1 - 4.5e-05 23.5 7.6 7.9e-05 22.7 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2655 PF10848.8 KXG54452.1 - 0.087 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2655) HSP70 PF00012.20 KXG54453.1 - 4.4e-09 35.1 0.1 5.7e-08 31.4 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein Hydantoinase_A PF01968.18 KXG54453.1 - 0.009 15.3 0.1 1.6 8.0 0.0 2.5 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase Tli4_N PF18443.1 KXG54454.1 - 0.019 15.4 0.8 0.042 14.2 0.8 1.6 1 0 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain MIEAP PF16026.5 KXG54454.1 - 0.027 14.7 5.3 0.41 10.8 5.3 2.4 1 1 0 1 1 1 0 Mitochondria-eating protein Fmp27_WPPW PF10359.9 KXG54454.1 - 0.047 12.5 3.7 0.048 12.5 2.2 1.6 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain V_ATPase_I PF01496.19 KXG54454.1 - 0.077 10.9 1.2 0.097 10.6 1.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Caps_synth_GfcC PF06251.11 KXG54454.1 - 0.22 11.1 1.2 0.38 10.4 1.2 1.3 1 0 0 1 1 1 0 Capsule biosynthesis GfcC BRE1 PF08647.11 KXG54454.1 - 8.7 6.5 11.2 4.8 7.3 8.4 2.1 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase PEP_mutase PF13714.6 KXG54455.1 - 1.8e-41 142.2 0.0 2.1e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KXG54455.1 - 8.9e-22 77.3 0.1 1.2e-21 76.8 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pcc1 PF09341.10 KXG54456.1 - 1e-31 108.9 0.2 1.5e-31 108.3 0.2 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF4571 PF15137.6 KXG54456.1 - 0.017 14.7 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) DUF1275 PF06912.11 KXG54457.1 - 9.6e-43 146.3 8.8 1.2e-42 146.0 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Lyase_aromatic PF00221.19 KXG54458.1 - 9.5e-147 489.4 6.8 1.2e-146 489.0 6.8 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase FAD_binding_4 PF01565.23 KXG54459.1 - 8.1e-31 106.6 6.2 2.1e-30 105.3 6.4 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXG54459.1 - 1.8e-11 43.9 0.1 3.6e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KXG54459.1 - 0.052 12.9 0.1 0.086 12.2 0.1 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DIOX_N PF14226.6 KXG54460.1 - 6.9e-27 94.6 0.0 1.3e-26 93.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXG54460.1 - 1.4e-16 60.9 0.0 2.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pec_lyase_C PF00544.19 KXG54461.1 - 3.5e-42 144.4 11.1 4.9e-42 143.9 11.1 1.3 1 0 0 1 1 1 1 Pectate lyase FAD_binding_3 PF01494.19 KXG54462.1 - 6.3e-11 42.1 0.0 2.9e-10 39.9 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXG54462.1 - 0.00012 21.8 2.7 0.00054 19.6 0.2 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXG54462.1 - 0.00012 22.2 0.1 0.00027 21.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXG54462.1 - 0.0026 17.1 0.8 0.022 14.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG54462.1 - 0.0068 16.4 0.4 0.056 13.4 0.1 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXG54462.1 - 0.018 14.3 0.1 0.033 13.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.16 KXG54463.1 - 1.1e-26 93.6 29.4 6.2e-25 87.9 11.2 3.0 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG54463.1 - 6.1 5.6 15.2 1.4 7.7 4.0 3.2 2 2 1 3 3 3 0 MFS_1 like family DUF4440 PF14534.6 KXG54464.1 - 3.9e-08 33.6 0.0 4.6e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) NUP PF06516.11 KXG54465.1 - 2.3e-136 454.1 0.2 2.6e-136 453.9 0.2 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Lipase_GDSL_2 PF13472.6 KXG54466.1 - 9.1e-22 78.3 0.4 1.7e-21 77.5 0.2 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXG54466.1 - 3.8e-13 49.9 0.0 6.4e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.16 KXG54467.1 - 1.5e-33 116.2 27.8 1.5e-33 116.2 27.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Cupin_2 PF07883.11 KXG54468.1 - 3.1e-06 26.8 0.0 5.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KXG54468.1 - 0.0057 16.3 0.0 0.037 13.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF861) ADH_zinc_N PF00107.26 KXG54469.1 - 9.2e-27 93.6 0.1 1.3e-26 93.1 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXG54469.1 - 5.9e-22 79.2 0.0 1.1e-21 78.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXG54469.1 - 1.7e-10 40.8 0.9 3.4e-10 39.8 0.2 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KXG54469.1 - 0.004 16.5 0.1 0.0063 15.8 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GDPD PF03009.17 KXG54470.1 - 1e-33 117.2 0.0 1.7e-33 116.4 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KXG54470.1 - 0.03 14.8 0.1 0.061 13.8 0.1 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family LIM PF00412.22 KXG54472.1 - 1.1e-15 57.6 23.1 1.8e-10 40.9 4.0 2.9 3 0 0 3 3 3 2 LIM domain Terminase_GpA PF05876.12 KXG54472.1 - 0.18 10.3 1.2 0.26 9.8 1.2 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Sugar_tr PF00083.24 KXG54474.1 - 1.2e-87 294.7 27.0 1.4e-87 294.4 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG54474.1 - 4.3e-19 68.6 37.5 4.3e-19 68.6 37.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_5 PF07994.12 KXG54475.1 - 1.4e-144 481.5 0.4 1.8e-144 481.0 0.0 1.3 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KXG54475.1 - 1.5e-45 153.9 0.7 3.2e-45 152.8 0.7 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase PALP PF00291.25 KXG54476.1 - 9.5e-42 143.4 0.1 1.2e-41 143.1 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_N PF08240.12 KXG54477.1 - 1.3e-25 89.4 2.3 1.3e-25 89.4 2.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXG54477.1 - 9.3e-19 67.7 1.0 2e-18 66.6 1.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXG54477.1 - 0.0081 15.5 1.9 0.015 14.6 1.9 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PQQ PF01011.21 KXG54477.1 - 0.013 15.4 0.1 0.034 14.1 0.1 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat Sacchrp_dh_NADP PF03435.18 KXG54477.1 - 0.021 15.1 0.1 0.038 14.3 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain zf-Tim10_DDP PF02953.15 KXG54478.1 - 5.5e-18 64.4 8.0 8e-18 63.9 8.0 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 KXG54478.1 - 0.00086 19.0 5.2 0.13 11.9 0.6 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF842) RhoGAP PF00620.27 KXG54479.1 - 3e-37 127.8 0.0 5.3e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain MFS_1 PF07690.16 KXG54480.1 - 3.8e-25 88.6 32.7 4.8e-25 88.2 31.8 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily AAT PF03417.16 KXG54481.1 - 4.3e-13 49.5 0.0 1.2e-12 48.0 0.0 1.7 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Fungal_trans PF04082.18 KXG54482.1 - 3.7e-25 88.5 0.4 6.3e-25 87.7 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PIG-F PF06699.11 KXG54483.1 - 3.9e-67 225.9 4.7 4.6e-67 225.7 4.7 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF4310 PF14187.6 KXG54483.1 - 0.071 12.8 0.1 0.19 11.4 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4310) Gly-zipper_YMGG PF13441.6 KXG54483.1 - 0.11 12.3 3.3 0.79 9.5 3.3 2.2 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 KXG54483.1 - 0.3 11.1 4.6 7.7 6.6 0.9 2.5 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.15 KXG54483.1 - 2.4 8.1 9.7 10 6.1 1.4 3.1 3 0 0 3 3 3 0 Glycine zipper 2TM domain Pkinase_Tyr PF07714.17 KXG54484.1 - 4e-09 36.1 0.2 5.8e-08 32.3 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXG54484.1 - 2.4e-06 27.1 0.0 3.6e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Fungal_trans PF04082.18 KXG54485.1 - 2.6e-07 29.9 0.0 4.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG54485.1 - 0.00063 19.8 5.6 0.0013 18.8 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 KXG54486.1 - 7.5e-16 58.7 0.1 2e-15 57.3 0.1 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 KXG54486.1 - 3.1e-11 43.5 0.0 7.8e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 KXG54486.1 - 4.3e-11 42.9 0.0 1.3e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Flavi_M PF01004.19 KXG54486.1 - 0.12 12.1 0.1 0.48 10.2 0.1 2.0 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M Glyco_hydro_18 PF00704.28 KXG54487.1 - 1.3e-60 205.8 0.0 1.4e-60 205.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.8 KXG54487.1 - 0.0091 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) Tautomerase_3 PF14832.6 KXG54488.1 - 7.8e-52 175.1 0.0 8.7e-52 175.0 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.21 KXG54488.1 - 0.0068 16.3 0.0 0.057 13.4 0.0 2.0 2 0 0 2 2 2 1 Tautomerase enzyme Epimerase PF01370.21 KXG54489.1 - 2.3e-17 63.3 0.1 5.2e-17 62.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXG54489.1 - 3.9e-11 42.5 0.0 1.7e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXG54489.1 - 2.2e-09 37.2 0.0 5.9e-08 32.5 0.0 2.6 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXG54489.1 - 2.6e-09 37.3 0.0 4.5e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KXG54489.1 - 5.9e-08 32.5 0.0 3.8e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_4 PF07993.12 KXG54489.1 - 3.8e-05 23.0 0.1 0.03 13.5 0.0 2.2 1 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KXG54489.1 - 9.5e-05 21.7 0.0 0.00015 21.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KXG54489.1 - 0.00041 19.9 1.0 0.00096 18.7 0.0 2.0 3 0 0 3 3 3 1 short chain dehydrogenase DUF5484 PF17583.2 KXG54489.1 - 0.21 11.3 0.3 0.46 10.2 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5484) zf-CCCH PF00642.24 KXG54490.1 - 2.4e-18 65.6 29.3 2.9e-06 27.1 1.0 5.2 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXG54490.1 - 1.7e-15 56.5 30.4 0.00012 21.9 2.5 5.2 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 KXG54490.1 - 3.3e-13 50.3 25.6 7.5e-06 26.6 0.6 5.3 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 KXG54490.1 - 2.3e-05 24.1 0.8 2.3e-05 24.1 0.8 4.8 5 0 0 5 5 5 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KXG54490.1 - 0.39 11.0 14.4 2.5 8.4 2.5 4.0 2 1 2 4 4 4 0 Zinc-finger containing family zf-C3H1 PF10650.9 KXG54490.1 - 0.4 10.5 6.7 0.64 9.8 0.1 3.7 4 0 0 4 4 4 0 Putative zinc-finger domain Nab2p_Zf1 PF18260.1 KXG54490.1 - 5.9 6.9 16.6 2.1 8.3 4.6 3.3 3 0 0 3 3 3 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 FMN_red PF03358.15 KXG54491.1 - 5.3e-08 32.8 0.0 6.9e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KXG54491.1 - 3.4e-07 30.2 0.0 4.3e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KXG54491.1 - 5.9e-05 23.3 0.2 0.0068 16.6 0.1 2.3 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KXG54491.1 - 0.0031 17.7 0.0 0.0083 16.4 0.0 1.7 1 1 0 1 1 1 1 Flavodoxin domain Sp38 PF07354.12 KXG54492.1 - 0.2 11.1 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) DUF3176 PF11374.8 KXG54494.1 - 2.6e-32 111.2 1.2 5.3e-32 110.2 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) NPL4 PF05021.15 KXG54495.1 - 1.3e-135 451.7 0.0 1.6e-135 451.4 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KXG54495.1 - 4.8e-68 227.9 0.1 7.8e-68 227.2 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KXG54495.1 - 0.11 13.0 0.0 20 5.8 0.0 3.4 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 DUF2417 PF10329.9 KXG54496.1 - 1.2e-81 273.6 0.0 1.6e-81 273.2 0.0 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) DUF2070 PF09843.9 KXG54496.1 - 3.1 6.0 8.2 4.3 5.5 8.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ABC2_membrane_3 PF12698.7 KXG54496.1 - 3.6 6.6 9.4 5.3 6.0 9.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Aldedh PF00171.22 KXG54497.1 - 1e-142 476.0 0.1 1.2e-142 475.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXG54497.1 - 0.0002 20.5 0.0 0.00031 19.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 KXG54497.1 - 0.076 12.4 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Cwf_Cwc_15 PF04889.12 KXG54498.1 - 0.0052 16.5 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3970 PF13113.6 KXG54498.1 - 0.036 14.3 0.1 0.036 14.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) AAA PF00004.29 KXG54500.1 - 2e-16 60.6 0.1 5.7e-16 59.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXG54500.1 - 0.0024 18.3 0.2 0.0058 17.0 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXG54500.1 - 0.017 15.4 0.3 0.15 12.3 0.3 2.5 1 1 1 2 2 2 0 AAA domain DNA_gyraseB_C PF00986.21 KXG54500.1 - 0.031 14.5 0.8 0.062 13.5 0.1 1.9 2 0 0 2 2 2 0 DNA gyrase B subunit, carboxyl terminus Torsin PF06309.11 KXG54500.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_33 PF13671.6 KXG54500.1 - 0.071 13.3 0.1 0.14 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXG54500.1 - 0.082 12.2 0.1 0.18 11.0 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin Zot PF05707.12 KXG54500.1 - 0.15 11.7 0.2 5.1 6.7 0.2 2.5 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) RuvB_N PF05496.12 KXG54500.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KXG54501.1 - 5.2e-05 23.2 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AF-4 PF05110.13 KXG54501.1 - 0.02 13.1 16.0 0.029 12.5 16.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MFMR_assoc PF16596.5 KXG54501.1 - 2.4 8.6 15.8 5.2 7.5 15.8 1.5 1 0 0 1 1 1 0 Disordered region downstream of MFMR Abhydrolase_6 PF12697.7 KXG54502.1 - 2e-19 71.1 0.1 3.7e-19 70.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG54502.1 - 0.00027 20.7 0.0 0.00088 19.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG54502.1 - 0.012 14.8 0.1 0.028 13.7 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 WD40 PF00400.32 KXG54503.1 - 1.2e-41 139.9 29.5 6.6e-08 33.1 0.6 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KXG54503.1 - 3.2e-39 134.1 0.2 4.7e-39 133.6 0.2 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KXG54503.1 - 6.3e-11 42.4 0.6 0.062 13.6 0.0 5.1 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXG54503.1 - 1.3e-05 24.1 3.9 0.0022 16.7 0.1 3.3 4 0 0 4 4 4 1 Nucleoporin Nup120/160 LisH PF08513.11 KXG54503.1 - 0.0021 17.9 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 KXG54503.1 - 0.029 14.3 0.3 0.13 12.2 0.0 2.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KXG54503.1 - 0.031 13.6 0.6 1.5 8.0 0.2 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF4550 PF15084.6 KXG54503.1 - 0.086 13.3 2.0 0.17 12.3 0.0 2.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4550) RAB3GAP2_N PF14655.6 KXG54503.1 - 0.15 11.3 0.1 2.8 7.1 0.0 2.6 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ge1_WD40 PF16529.5 KXG54503.1 - 0.47 9.4 1.3 51 2.7 0.1 3.7 4 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Med11 PF10280.9 KXG54504.1 - 3.1e-36 124.8 0.0 5.1e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 Mediator complex protein Hexokinase_2 PF03727.16 KXG54504.1 - 0.099 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Hexokinase DUF1385 PF07136.11 KXG54504.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) DUF3141 PF11339.8 KXG54504.1 - 0.15 10.5 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) F_actin_cap_B PF01115.17 KXG54505.1 - 4.9e-106 353.7 0.0 5.7e-106 353.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 KXG54505.1 - 0.1 12.0 0.0 0.26 10.7 0.0 1.8 1 1 0 1 1 1 0 F-actin capping protein alpha subunit HD PF01966.22 KXG54506.1 - 0.00015 22.0 0.8 0.00042 20.5 0.8 1.8 1 1 0 1 1 1 1 HD domain SARAF PF06682.12 KXG54507.1 - 0.0019 17.9 8.3 0.0022 17.7 8.3 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis SPX PF03105.19 KXG54507.1 - 0.12 12.3 8.3 0.13 12.1 8.3 1.0 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 KXG54507.1 - 0.16 11.1 12.4 0.19 10.9 12.4 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Zip PF02535.22 KXG54507.1 - 0.54 9.4 3.7 0.77 8.9 3.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 KXG54507.1 - 2.1 7.1 5.9 2.1 7.1 5.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 KXG54507.1 - 2.4 6.3 7.4 2.6 6.1 7.4 1.0 1 0 0 1 1 1 0 Nop14-like family RAP1 PF07218.11 KXG54507.1 - 3.8 5.7 15.0 3.8 5.7 15.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Apt1 PF10351.9 KXG54507.1 - 8 5.2 12.3 9.3 5.0 12.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ResIII PF04851.15 KXG54508.1 - 4.8e-21 75.5 0.0 9e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXG54508.1 - 2.4e-20 72.9 0.0 1e-19 70.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXG54508.1 - 3.3e-17 62.8 0.0 1e-16 61.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KXG54508.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_22 PF13401.6 KXG54508.1 - 0.11 12.8 0.0 0.31 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain Ank_2 PF12796.7 KXG54509.1 - 2.3e-17 63.3 5.0 1.3e-08 35.2 0.0 4.8 2 1 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG54509.1 - 5.6e-10 39.5 6.3 6.6e-05 23.4 0.0 5.0 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXG54509.1 - 8.8e-09 35.5 8.8 1.2e-07 31.8 0.1 4.2 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG54509.1 - 1.9e-08 33.9 12.1 0.016 15.7 0.0 7.3 8 0 0 8 8 8 2 Ankyrin repeat AAA_22 PF13401.6 KXG54509.1 - 4.5e-06 27.0 0.8 0.0023 18.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KXG54509.1 - 6.5e-06 26.2 0.1 3.3e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Ank PF00023.30 KXG54509.1 - 1.4e-05 25.3 11.3 0.02 15.3 0.1 6.0 7 0 0 7 7 7 2 Ankyrin repeat Hira PF07569.11 KXG54510.1 - 0.22 11.2 0.0 21 4.7 0.0 2.9 2 1 0 3 3 3 0 TUP1-like enhancer of split DPM2 PF07297.12 KXG54511.1 - 4.2e-32 110.3 1.4 4.8e-32 110.1 1.4 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KXG54511.1 - 0.00019 21.3 0.6 0.00024 21.0 0.6 1.1 1 0 0 1 1 1 1 PIG-P DUF1772 PF08592.11 KXG54511.1 - 0.014 15.7 0.6 0.015 15.6 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Phage_holin_3_6 PF07332.11 KXG54511.1 - 0.033 14.2 1.5 0.039 14.0 1.5 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III LapA_dom PF06305.11 KXG54511.1 - 0.044 13.6 0.1 0.044 13.6 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4229 PF14012.6 KXG54511.1 - 0.075 13.1 1.5 0.18 11.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) COX14 PF14880.6 KXG54511.1 - 0.44 10.4 0.0 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly MA3 PF02847.17 KXG54512.1 - 5.9e-28 97.1 0.3 1.3e-27 96.0 0.1 1.7 2 0 0 2 2 2 1 MA3 domain RPN2_C PF18004.1 KXG54512.1 - 8 6.4 8.5 3.7 7.5 1.2 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain SET PF00856.28 KXG54513.1 - 5.1e-10 40.0 0.0 2e-08 34.8 0.0 2.5 2 1 0 2 2 2 1 SET domain TPR_9 PF13371.6 KXG54513.1 - 0.095 12.9 0.2 0.27 11.4 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-MYND PF01753.18 KXG54513.1 - 0.25 11.4 3.5 0.62 10.2 3.5 1.7 1 0 0 1 1 1 0 MYND finger WD40 PF00400.32 KXG54514.1 - 7.3e-23 80.4 12.4 2.7e-06 28.0 0.3 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG54514.1 - 0.00085 19.6 0.1 0.062 13.6 0.0 3.4 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain UL40 PF10682.9 KXG54514.1 - 0.022 14.4 0.1 0.067 12.9 0.0 1.8 2 0 0 2 2 2 0 Glycoprotein of human cytomegalovirus HHV-5 Lebercilin PF15619.6 KXG54515.1 - 0.017 14.8 1.5 0.017 14.8 1.5 1.8 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease BAF1_ABF1 PF04684.13 KXG54515.1 - 0.19 10.8 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PALP PF00291.25 KXG54517.1 - 6.3e-54 183.4 0.9 3.6e-28 98.8 0.1 2.1 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme Glucosamine_iso PF01182.20 KXG54518.1 - 6.4e-67 225.7 0.0 7.3e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase RRM_1 PF00076.22 KXG54520.1 - 1.9e-11 43.6 0.0 5.2e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXG54520.1 - 0.018 14.6 0.0 0.046 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RabGAP-TBC PF00566.18 KXG54521.1 - 7e-28 97.7 0.0 1.1e-23 84.0 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain MAP65_ASE1 PF03999.12 KXG54521.1 - 1.6 7.3 4.2 2.2 6.9 4.2 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) EF-hand_6 PF13405.6 KXG54522.1 - 1.4e-12 46.5 4.3 1.6e-06 27.5 0.3 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KXG54522.1 - 2.8e-11 42.1 2.6 7.9e-06 25.1 0.4 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KXG54522.1 - 7.4e-09 35.9 5.9 5.8e-08 33.1 0.8 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KXG54522.1 - 2.6e-06 27.2 1.8 0.0056 16.5 0.1 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KXG54522.1 - 1.8e-05 24.0 7.0 0.024 14.1 1.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 KXG54522.1 - 7.2e-05 23.0 0.1 0.028 14.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Afi1 PF07792.12 KXG54523.1 - 8.9e-45 152.4 0.5 1.6e-44 151.7 0.5 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 KXG54523.1 - 1.1e-38 131.7 0.0 1.7e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KXG54523.1 - 1.1e-09 37.5 0.0 0.0028 16.4 0.0 4.1 3 2 2 5 5 5 3 Transport protein Avl9 DUF2347 PF09804.9 KXG54523.1 - 0.077 12.6 0.0 0.28 10.7 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Phos_pyr_kin PF08543.12 KXG54525.1 - 3.5e-13 49.5 0.0 1.4e-12 47.6 0.0 1.8 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KXG54525.1 - 8e-06 25.4 2.2 3.4e-05 23.3 0.0 2.4 3 0 0 3 3 3 1 pfkB family carbohydrate kinase dUTPase PF00692.19 KXG54526.1 - 8e-45 151.7 0.0 1e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 KXG54526.1 - 0.044 12.6 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) APH PF01636.23 KXG54527.1 - 4e-39 135.0 0.0 6.9e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXG54527.1 - 0.00018 20.9 0.0 0.00053 19.4 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 KXG54527.1 - 0.0018 17.9 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.20 KXG54527.1 - 0.0091 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KXG54527.1 - 0.023 13.6 0.0 0.54 9.1 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) Kdo PF06293.14 KXG54527.1 - 0.05 12.9 0.0 0.44 9.9 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.14 KXG54527.1 - 0.055 12.7 0.0 0.85 8.8 0.0 2.2 1 1 0 1 1 1 0 Fructosamine kinase zf-C2H2 PF00096.26 KXG54528.1 - 4e-07 30.1 13.0 0.0051 17.2 2.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXG54528.1 - 2e-05 24.8 7.0 0.67 10.5 0.2 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXG54528.1 - 0.02 15.7 12.0 0.11 13.4 1.8 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 KXG54528.1 - 1.5 9.2 7.8 0.28 11.5 1.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PGAP1 PF07819.13 KXG54529.1 - 0.00016 21.5 0.0 0.00026 20.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KXG54529.1 - 0.00024 20.7 0.1 0.00057 19.4 0.1 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KXG54529.1 - 0.0044 17.7 0.0 0.0058 17.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXG54529.1 - 0.012 15.3 0.2 0.03 14.0 0.2 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXG54529.1 - 0.072 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 zf-C2H2 PF00096.26 KXG54530.1 - 0.0029 18.0 0.1 0.0029 18.0 0.1 3.5 3 1 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 KXG54530.1 - 0.05 14.2 0.0 0.05 14.2 0.0 2.2 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KXG54530.1 - 0.11 13.4 0.1 0.11 13.4 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KXG54530.1 - 2.7 8.1 4.7 4.8 7.3 0.0 2.3 1 1 2 3 3 3 0 Aberrant zinc-finger PQ-loop PF04193.14 KXG54531.1 - 6.8e-34 115.5 11.6 1.2e-16 60.2 3.0 2.5 2 0 0 2 2 2 2 PQ loop repeat Cytochrom_B561 PF03188.16 KXG54532.1 - 0.0088 16.2 11.7 0.026 14.6 8.4 2.9 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 SARAF PF06682.12 KXG54532.1 - 0.04 13.6 10.7 0.13 11.9 0.1 3.3 2 1 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4191 PF13829.6 KXG54532.1 - 9.4 5.5 6.7 0.6 9.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Ank_2 PF12796.7 KXG54533.1 - 1.7e-54 182.4 0.1 1.1e-17 64.4 0.0 5.6 1 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXG54533.1 - 7.8e-38 128.4 0.2 1.4e-09 38.3 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG54533.1 - 2.3e-35 116.6 1.3 0.00086 19.6 0.0 11.4 12 0 0 12 12 11 6 Ankyrin repeat Ank PF00023.30 KXG54533.1 - 1.2e-32 110.9 10.4 0.00071 19.9 0.0 11.4 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 KXG54533.1 - 1.5e-29 101.7 5.7 9.8e-08 32.1 0.0 8.9 2 2 7 9 9 9 7 Ankyrin repeats (many copies) NACHT_N PF17100.5 KXG54533.1 - 1.4e-24 87.2 0.1 2.9e-24 86.1 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KXG54533.1 - 1.1e-08 35.1 0.1 2.7e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXG54533.1 - 3.4e-06 27.6 1.3 9.3e-06 26.1 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KXG54533.1 - 0.015 15.3 0.1 0.13 12.3 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXG54533.1 - 0.021 15.1 0.0 0.07 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KXG54533.1 - 0.11 11.7 0.1 1.5 8.0 0.1 2.3 1 1 0 2 2 2 0 KAP family P-loop domain Sep15_SelM PF08806.11 KXG54533.1 - 0.15 12.3 0.0 34 4.7 0.0 2.9 2 0 0 2 2 2 0 Sep15/SelM redox domain UME PF08064.13 KXG54533.1 - 0.16 11.9 0.5 15 5.6 0.0 3.2 3 0 0 3 3 3 0 UME (NUC010) domain ATP-synt_DE_N PF02823.16 KXG54535.1 - 1e-17 63.8 0.1 1.6e-17 63.2 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain LisH PF08513.11 KXG54536.1 - 0.00094 19.1 0.0 0.0025 17.7 0.0 1.8 1 0 0 1 1 1 1 LisH ANAPC4_WD40 PF12894.7 KXG54536.1 - 0.0038 17.5 0.1 0.021 15.1 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain NCBP3 PF10309.9 KXG54537.1 - 9.3e-21 73.4 0.0 1.5e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Trypan_PARP PF05887.11 KXG54537.1 - 8.2 6.4 8.5 1.7 8.6 2.0 2.6 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) Glyco_hydro_31 PF01055.26 KXG54538.1 - 4.5e-113 378.7 4.9 5.6e-113 378.4 4.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 KXG54538.1 - 4.2e-05 23.8 0.0 7.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 KXG54538.1 - 0.00069 19.9 3.7 0.0015 18.8 0.2 3.0 3 1 0 3 3 3 1 Galactose mutarotase-like UPF0449 PF15136.6 KXG54538.1 - 0.027 14.9 0.0 0.3 11.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Myb_DNA-binding PF00249.31 KXG54539.1 - 1.1e-26 92.7 2.4 1.7e-15 57.0 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXG54539.1 - 1.2e-17 63.8 7.1 9.3e-15 54.6 0.1 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain DUF2774 PF11242.8 KXG54539.1 - 0.013 15.6 0.0 0.041 14.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Myb_DNA-bind_4 PF13837.6 KXG54539.1 - 0.086 13.2 1.2 0.3 11.5 0.1 2.2 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain HTH_23 PF13384.6 KXG54539.1 - 0.15 11.9 0.4 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain Glyco_transf_41 PF13844.6 KXG54540.1 - 9.4e-104 347.5 0.0 1.5e-52 178.6 0.0 3.1 2 1 1 3 3 3 3 Glycosyl transferase family 41 TPR_1 PF00515.28 KXG54540.1 - 5.6e-16 57.6 4.2 5.3e-05 22.9 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXG54540.1 - 1.1e-14 53.8 8.5 4.9e-05 22.9 0.1 6.1 3 2 3 6 6 6 4 TPR repeat TPR_2 PF07719.17 KXG54540.1 - 1.3e-13 49.9 8.6 0.033 14.3 0.0 5.9 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXG54540.1 - 2.5e-11 42.8 1.9 0.00026 21.0 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXG54540.1 - 9.1e-09 35.7 1.6 0.021 15.3 0.2 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXG54540.1 - 1.9e-08 34.1 4.2 0.68 10.4 0.2 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXG54540.1 - 5.4e-07 29.8 6.9 0.021 15.1 0.2 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXG54540.1 - 7.5e-07 28.8 12.4 0.025 14.4 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXG54540.1 - 2.9e-06 27.6 9.4 0.53 11.2 0.0 6.1 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXG54540.1 - 2.9e-06 26.9 1.0 0.86 9.8 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXG54540.1 - 0.00039 21.0 10.5 0.51 11.0 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 KXG54540.1 - 0.012 16.1 0.1 0.76 10.2 0.0 2.7 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_15 PF13429.6 KXG54540.1 - 0.03 13.6 0.6 0.72 9.0 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXG54540.1 - 0.056 13.6 0.1 0.056 13.6 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG54540.1 - 0.084 13.1 0.9 0.54 10.5 0.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Ribosomal_L11_N PF03946.14 KXG54541.1 - 2.4e-24 84.9 0.1 3.8e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KXG54541.1 - 1.7e-14 54.0 0.3 2.6e-14 53.5 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.15 KXG54542.1 - 3.7e-81 272.3 0.0 5.4e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KXG54542.1 - 6.3e-29 100.6 0.0 1.3e-28 99.6 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KXG54542.1 - 2.1e-24 85.3 0.0 4.3e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KXG54542.1 - 3.9e-16 58.8 3.0 7.9e-16 57.8 3.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXG54542.1 - 2.2e-12 46.7 0.0 5.4e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KXG54542.1 - 0.023 14.1 0.1 0.055 12.9 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DNA_primase_lrg PF04104.14 KXG54543.1 - 9.8e-90 300.6 0.0 1.3e-89 300.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit ADK PF00406.22 KXG54544.1 - 4.2e-34 117.8 0.0 5.9e-19 68.7 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 KXG54544.1 - 1.2e-15 57.2 0.0 1.9e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KXG54544.1 - 1.5e-14 54.6 0.0 5.1e-11 43.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXG54544.1 - 2.2e-05 25.0 0.0 8.3e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXG54544.1 - 0.0028 17.8 0.0 0.015 15.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF3446 PF11928.8 KXG54544.1 - 0.032 14.5 7.6 0.059 13.7 7.6 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain Lipase_GDSL PF00657.22 KXG54544.1 - 0.055 13.4 0.2 0.25 11.3 0.2 1.8 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase AAA_5 PF07728.14 KXG54544.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KXG54544.1 - 0.16 12.2 0.1 0.32 11.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KXG54544.1 - 0.17 10.9 0.1 0.23 10.4 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Guanylate_kin PF00625.21 KXG54544.1 - 0.18 11.5 0.1 3.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase SNase PF00565.17 KXG54545.1 - 3.7e-21 75.6 0.0 5.1e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Mito_carr PF00153.27 KXG54546.1 - 5.8e-55 183.2 0.6 9.9e-20 70.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.21 KXG54547.1 - 4.8e-28 98.0 0.0 7.8e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KXG54547.1 - 9.8e-10 38.8 0.0 9.9e-07 29.1 0.0 3.4 3 1 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.18 KXG54547.1 - 0.022 14.8 4.1 0.035 14.2 4.1 1.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Vta1 PF04652.16 KXG54548.1 - 5.8e-49 165.8 0.1 9e-49 165.2 0.1 1.3 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 KXG54548.1 - 2e-16 59.4 0.1 4.1e-16 58.4 0.1 1.6 1 0 0 1 1 1 1 Vta1 C-terminal domain MAAL_C PF07476.11 KXG54548.1 - 0.099 11.8 0.2 0.15 11.2 0.2 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Epimerase PF01370.21 KXG54549.1 - 5.5e-19 68.6 0.0 8.1e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXG54549.1 - 3.2e-08 32.9 0.0 1.9e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXG54549.1 - 9.1e-08 31.9 0.0 2.2e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXG54549.1 - 1.7e-06 27.4 0.0 2.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KXG54549.1 - 0.0095 15.4 0.0 0.024 14.1 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Ldh_1_N PF00056.23 KXG54549.1 - 0.01 15.9 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 KXG54549.1 - 0.03 14.2 0.1 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 KR domain Sacchrp_dh_NADP PF03435.18 KXG54549.1 - 0.035 14.4 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KXG54549.1 - 0.055 13.7 0.0 0.19 12.0 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Topoisom_I_N PF02919.15 KXG54550.1 - 5e-96 320.3 3.8 5e-96 320.3 3.8 3.7 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 KXG54550.1 - 1.3e-95 319.0 7.9 1.3e-95 319.0 7.9 2.2 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 KXG54550.1 - 1e-33 115.1 1.1 4e-33 113.2 1.1 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain ATP-synt PF00231.19 KXG54551.1 - 1.6e-75 254.4 6.8 2e-75 254.1 6.8 1.0 1 0 0 1 1 1 1 ATP synthase DnaJ PF00226.31 KXG54552.1 - 3.1e-17 62.4 0.1 9e-17 61.0 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain Lactococcin_972 PF09683.10 KXG54552.1 - 0.063 13.8 14.4 1.1 9.9 1.9 3.9 2 1 1 3 3 3 0 Bacteriocin (Lactococcin_972) ARD PF03079.14 KXG54552.1 - 7 6.8 7.1 2.8 8.1 1.1 2.5 3 0 0 3 3 3 0 ARD/ARD' family F-box-like PF12937.7 KXG54553.1 - 1.2e-07 31.5 0.1 2.8e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXG54553.1 - 1.5e-06 27.9 0.1 3.5e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain Peptidase_M74 PF03411.13 KXG54553.1 - 0.15 11.6 0.1 0.58 9.7 0.0 1.8 2 0 0 2 2 2 0 Penicillin-insensitive murein endopeptidase Thioredoxin PF00085.20 KXG54554.1 - 4.7e-31 106.8 0.0 2.6e-26 91.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KXG54554.1 - 5e-07 30.2 0.3 0.0028 18.1 0.1 2.6 1 1 1 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KXG54554.1 - 6.4e-07 29.0 0.0 6.7e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KXG54554.1 - 0.003 17.8 0.0 2.8 8.3 0.0 3.5 3 1 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 KXG54554.1 - 0.0099 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family QSOX_Trx1 PF18108.1 KXG54554.1 - 0.04 14.1 0.0 0.099 12.8 0.0 1.6 1 0 0 1 1 1 0 QSOX Trx-like domain Thioredoxin_7 PF13899.6 KXG54554.1 - 0.041 14.1 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.6 KXG54554.1 - 0.11 12.6 0.1 4.3 7.5 0.1 2.5 2 0 0 2 2 2 0 Thioredoxin domain TraF PF13728.6 KXG54554.1 - 0.21 11.4 0.0 0.21 11.4 0.0 3.8 4 0 0 4 4 4 0 F plasmid transfer operon protein GNAT_acetyltr_2 PF13718.6 KXG54555.1 - 1.2e-97 325.8 0.0 2.2e-97 324.9 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KXG54555.1 - 1.4e-82 276.9 0.0 2.6e-82 276.1 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KXG54555.1 - 1.8e-65 220.1 0.0 6.5e-65 218.3 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KXG54555.1 - 4.6e-35 119.4 0.0 1.2e-34 118.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KXG54555.1 - 0.00077 19.2 0.0 0.033 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXG54555.1 - 0.012 16.0 0.0 0.035 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.25 KXG54555.1 - 0.014 15.6 0.0 0.057 13.7 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family AAA_22 PF13401.6 KXG54555.1 - 0.028 14.7 0.1 0.89 9.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain GHMP_kinases_N PF00288.26 KXG54555.1 - 0.1 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 GHMP kinases N terminal domain ALO PF04030.14 KXG54556.1 - 2.3e-10 40.7 4.7 7.2e-10 39.1 4.7 1.6 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Chol_subst-bind PF09129.11 KXG54556.1 - 0.00013 21.1 9.3 0.024 13.6 9.3 2.5 1 1 0 1 1 1 1 Cholesterol oxidase, substrate-binding FAD_binding_4 PF01565.23 KXG54556.1 - 0.00083 19.1 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain FA_hydroxylase PF04116.13 KXG54557.1 - 0.00013 22.3 1.2 0.00021 21.6 1.2 1.3 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily DUF498 PF04430.14 KXG54557.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) Sigma70_r1_1 PF03979.14 KXG54557.1 - 0.18 11.9 0.0 0.29 11.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 DJ-1_PfpI PF01965.24 KXG54558.1 - 1.3e-13 51.0 0.0 2.6e-13 50.1 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family Peptidase_S64 PF08192.11 KXG54559.1 - 0.038 12.5 0.0 0.081 11.4 0.0 1.5 2 0 0 2 2 2 0 Peptidase family S64 Trypsin PF00089.26 KXG54559.1 - 0.06 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Trypsin Peptidase_S32 PF05579.13 KXG54559.1 - 0.098 11.8 1.3 0.18 11.0 1.0 1.5 1 1 1 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Glyco_hydro_16 PF00722.21 KXG54560.1 - 1.2e-08 34.6 0.0 4.8e-08 32.7 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Vps8 PF12816.7 KXG54561.1 - 1.1e-64 217.6 0.0 2.5e-64 216.5 0.0 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KXG54561.1 - 4.4e-08 33.1 0.0 0.0015 18.4 0.0 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS Pox_D3 PF04580.13 KXG54561.1 - 0.0019 17.9 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 Chordopoxvirinae D3 protein zf-C3H2C3 PF17122.5 KXG54561.1 - 0.0027 17.7 0.4 0.0027 17.7 0.4 2.6 3 0 0 3 3 3 1 Zinc-finger zf-RING_5 PF14634.6 KXG54561.1 - 0.035 14.1 0.6 0.093 12.7 0.1 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXG54561.1 - 0.079 12.8 0.0 0.079 12.8 0.0 2.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXG54561.1 - 0.2 11.4 0.3 0.7 9.7 0.3 2.0 1 0 0 1 1 1 0 RING-like zinc finger Transferase PF02458.15 KXG54562.1 - 0.026 13.2 0.0 0.065 11.9 0.0 1.6 2 0 0 2 2 2 0 Transferase family 2-oxoacid_dh PF00198.23 KXG54562.1 - 0.19 11.2 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Peptidase_S9 PF00326.21 KXG54565.1 - 1.8e-53 181.2 0.1 3e-53 180.5 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KXG54565.1 - 1.1e-05 24.5 0.1 1.7e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family PD40 PF07676.12 KXG54565.1 - 0.0033 17.3 0.2 0.086 12.8 0.0 3.0 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Esterase PF00756.20 KXG54565.1 - 0.044 13.4 0.3 0.08 12.6 0.3 1.4 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.12 KXG54565.1 - 0.092 11.4 0.4 2.6 6.6 0.4 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) DNA_ligase_A_M PF01068.21 KXG54566.1 - 4.5e-59 199.5 0.6 5.3e-57 192.8 0.6 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXG54566.1 - 1.6e-44 152.3 0.0 3e-44 151.4 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KXG54566.1 - 1.7e-26 92.7 0.0 8.7e-26 90.4 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KXG54566.1 - 1.8e-05 25.2 0.1 3.1e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 RNA ligase XRCC4 PF06632.12 KXG54566.1 - 2 7.2 13.9 3.5 6.4 13.9 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 eIF-5_eIF-2B PF01873.17 KXG54568.1 - 6.8e-39 132.4 0.0 1.5e-38 131.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KXG54568.1 - 1.4e-21 76.4 0.1 3.7e-21 75.0 0.1 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Zn-ribbon_8 PF09723.10 KXG54568.1 - 0.29 11.3 1.0 0.77 9.9 1.0 1.7 1 0 0 1 1 1 0 Zinc ribbon domain HK PF02110.15 KXG54569.1 - 7e-73 245.0 0.0 1.3e-72 244.2 0.0 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KXG54569.1 - 6e-62 208.2 1.9 9e-62 207.6 1.9 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 KXG54569.1 - 0.00057 19.4 0.1 0.0013 18.2 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate kinase PCP_red PF08369.10 KXG54569.1 - 0.1 12.8 0.0 0.39 11.0 0.0 2.0 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Isochorismatase PF00857.20 KXG54570.1 - 4.9e-28 98.5 0.0 6.3e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF3632 PF12311.8 KXG54572.1 - 1.7e-30 106.8 0.4 2.2e-30 106.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Lipase_GDSL_2 PF13472.6 KXG54573.1 - 5.1e-25 88.9 0.0 2.1e-24 86.9 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXG54573.1 - 2.4e-15 57.0 0.0 3.2e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KXG54573.1 - 0.13 12.3 0.0 0.4 10.8 0.0 1.7 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Voltage_CLC PF00654.20 KXG54574.1 - 1.2e-88 297.8 28.5 2.2e-88 296.9 23.1 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel PqiA PF04403.13 KXG54574.1 - 0.0075 16.1 0.8 0.0075 16.1 0.8 2.4 3 1 0 3 3 3 1 Paraquat-inducible protein A TAT_signal PF10518.9 KXG54574.1 - 5.1 7.1 7.0 1 9.3 1.2 2.8 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence DHFR_1 PF00186.19 KXG54576.1 - 6.5e-20 71.4 0.0 2.2e-13 50.2 0.0 2.5 2 1 0 2 2 2 2 Dihydrofolate reductase Med22 PF06179.12 KXG54577.1 - 4.9e-18 65.3 0.2 8.1e-18 64.6 0.2 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Syntaxin_2 PF14523.6 KXG54577.1 - 0.057 13.8 0.0 0.68 10.3 0.0 2.1 2 0 0 2 2 2 0 Syntaxin-like protein Cwf_Cwc_15 PF04889.12 KXG54578.1 - 1.5e-84 283.6 15.8 1.9e-84 283.3 15.8 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein PA26 PF04636.13 KXG54578.1 - 0.89 8.4 3.9 1.2 8.0 3.9 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Merozoite_SPAM PF07133.11 KXG54578.1 - 5 7.1 23.7 9 6.3 23.7 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RR_TM4-6 PF06459.12 KXG54578.1 - 7.7 6.3 11.1 11 5.8 11.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNase_PH PF01138.21 KXG54579.1 - 2.5e-17 63.6 0.0 4.2e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXG54579.1 - 7.3e-07 29.1 0.0 1.6e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PhoLip_ATPase_C PF16212.5 KXG54580.1 - 4.5e-81 272.3 20.3 4.5e-81 272.3 20.3 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXG54580.1 - 9.6e-26 89.3 11.0 3.2e-25 87.6 11.0 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KXG54580.1 - 1.5e-11 45.0 0.8 1.8e-06 28.4 0.1 3.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXG54580.1 - 4.8e-11 42.6 0.0 1.8e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KXG54580.1 - 4.6e-05 23.0 1.6 5.1e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXG54580.1 - 0.0056 16.4 0.0 0.02 14.7 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PBP_N PF17093.5 KXG54580.1 - 3.3 8.0 10.6 3.8 7.8 2.5 2.8 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus DNA_pol_lambd_f PF10391.9 KXG54581.1 - 4e-21 74.6 1.0 9e-21 73.4 1.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KXG54581.1 - 9.9e-21 73.7 0.1 4.9e-20 71.5 0.4 2.1 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KXG54581.1 - 1e-16 61.2 0.1 2.3e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KXG54581.1 - 1.8e-10 41.0 0.0 8.3e-10 38.9 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KXG54581.1 - 0.00015 22.3 0.0 0.0058 17.2 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KXG54581.1 - 0.038 14.3 0.1 0.098 13.0 0.1 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH_2 PF12826.7 KXG54581.1 - 0.07 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif RT_RNaseH_2 PF17919.1 KXG54582.1 - 0.0081 16.2 0.0 0.037 14.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase NicO PF03824.16 KXG54583.1 - 2.4e-63 214.1 12.2 1.3e-59 201.9 5.7 2.3 2 0 0 2 2 2 2 High-affinity nickel-transport protein AA_permease PF00324.21 KXG54585.1 - 6.1e-129 430.7 37.5 7.5e-129 430.4 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXG54585.1 - 3.3e-35 121.7 37.4 4.2e-35 121.4 37.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4500 PF14937.6 KXG54585.1 - 4.7 7.3 4.7 28 4.8 0.0 3.6 4 1 1 5 5 5 0 Domain of unknown function (DUF4500) Peptidase_M14 PF00246.24 KXG54586.1 - 6.7e-78 262.4 0.0 8.3e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.20 KXG54587.1 - 1.1e-29 103.4 0.1 1.9e-29 102.7 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KXG54587.1 - 1.1e-05 25.9 0.2 3.9e-05 24.1 0.2 2.0 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 KXG54587.1 - 5.9e-05 23.4 0.2 0.00016 22.0 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_UBOX PF13445.6 KXG54588.1 - 3e-06 27.1 9.5 0.00019 21.4 4.0 2.9 2 1 0 2 2 2 2 RING-type zinc-finger zf-NOSIP PF15906.5 KXG54588.1 - 0.00012 22.1 0.0 0.00037 20.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_2 PF13639.6 KXG54588.1 - 0.00026 21.3 12.7 0.0025 18.1 3.8 2.9 3 0 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.6 KXG54588.1 - 0.00031 20.7 6.7 0.00031 20.7 6.7 2.7 2 2 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXG54588.1 - 0.0005 19.9 11.8 0.00084 19.1 4.8 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXG54588.1 - 0.0012 18.6 14.6 0.0074 16.1 3.9 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXG54588.1 - 0.0059 16.5 4.4 0.0059 16.5 4.4 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KXG54588.1 - 0.057 13.6 14.0 0.11 12.6 5.8 3.5 2 2 1 3 3 3 0 FYVE zinc finger zf-C3HC4_5 PF17121.5 KXG54588.1 - 0.13 12.1 2.8 0.37 10.7 2.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Atg14 PF10186.9 KXG54588.1 - 2 7.5 15.3 0.02 14.0 7.1 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C3HC4_4 PF15227.6 KXG54588.1 - 2.7 8.2 12.7 0.34 11.1 2.2 3.3 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Vps39_2 PF10367.9 KXG54588.1 - 5 7.6 11.6 0.24 11.9 1.0 3.3 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 Prok-RING_4 PF14447.6 KXG54588.1 - 7.8 6.5 19.7 3.2 7.7 8.3 3.7 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 DUF4407 PF14362.6 KXG54588.1 - 8.9 5.6 9.6 1.7 7.9 3.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Endonuclease_NS PF01223.23 KXG54589.1 - 1.9e-64 217.6 0.0 2.3e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Zip PF02535.22 KXG54590.1 - 7.4e-26 91.2 9.2 6.3e-17 61.8 5.3 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter DUF2975 PF11188.8 KXG54590.1 - 1.1 9.2 8.3 0.9 9.4 4.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) NB-ARC PF00931.22 KXG54591.1 - 5.6e-07 29.0 0.0 2.1e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 KXG54591.1 - 6.4e-06 26.2 0.0 2.4e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KXG54591.1 - 8.2e-06 26.3 0.0 5.7e-05 23.6 0.0 2.5 1 0 0 1 1 1 1 AAA ATPase domain TPR_12 PF13424.6 KXG54591.1 - 0.00014 22.1 9.3 0.13 12.5 0.1 5.4 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.6 KXG54591.1 - 0.005 17.1 0.0 0.053 13.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXG54591.1 - 0.019 15.3 0.0 0.069 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXG54591.1 - 0.043 13.1 0.0 0.13 11.5 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 KXG54591.1 - 0.091 12.5 0.1 0.42 10.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF2040 PF09745.9 KXG54592.1 - 2.7e-38 130.7 18.3 2.7e-38 130.7 18.3 3.7 4 1 0 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) Sedlin_N PF04628.13 KXG54593.1 - 1.4e-43 148.1 0.0 1.7e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KXG54593.1 - 0.00013 21.9 0.0 0.00068 19.6 0.0 1.9 2 0 0 2 2 2 1 Sybindin-like family Isochorismatase PF00857.20 KXG54594.1 - 6.6e-44 150.2 0.0 2.6e-43 148.2 0.0 1.8 2 0 0 2 2 2 1 Isochorismatase family FAR1 PF03101.15 KXG54594.1 - 1.7e-05 25.4 0.0 3.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.11 KXG54594.1 - 0.0093 16.4 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 1 Transcription factor AFT Catalase_C PF18011.1 KXG54594.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain found in long catalases NUDE_C PF04880.13 KXG54595.1 - 1e-63 215.0 7.4 1e-63 215.0 7.4 4.4 4 1 1 5 5 3 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 KXG54595.1 - 0.0083 16.5 6.8 0.0083 16.5 6.8 4.7 2 1 1 3 3 2 1 Cell division protein ZapB PSII_Pbs27 PF13326.6 KXG54595.1 - 0.13 12.6 4.0 0.28 11.5 4.0 1.6 1 0 0 1 1 1 0 Photosystem II Pbs27 Tho2 PF11262.8 KXG54595.1 - 0.13 11.4 16.7 0.022 14.0 1.1 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 ERM PF00769.19 KXG54595.1 - 0.21 11.4 28.6 0.42 10.4 28.6 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.12 KXG54595.1 - 0.29 11.2 29.9 1.4 8.9 8.2 3.9 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 KXG54595.1 - 0.69 9.4 28.0 3.1 7.3 12.0 2.5 1 1 1 2 2 2 0 Intermediate filament protein DUF4201 PF13870.6 KXG54595.1 - 0.85 9.3 23.4 0.11 12.2 1.7 3.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF745 PF05335.13 KXG54595.1 - 1 9.1 10.6 1.9 8.2 10.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) ADIP PF11559.8 KXG54595.1 - 1.1 9.4 29.7 1.3 9.1 3.5 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 KXG54595.1 - 1.2 9.6 24.8 0.84 10.1 7.5 2.8 2 1 1 3 3 3 0 Fez1 APG6_N PF17675.1 KXG54595.1 - 1.9 9.0 37.5 0.28 11.7 8.1 3.3 1 1 2 3 3 3 0 Apg6 coiled-coil region PRKG1_interact PF15898.5 KXG54595.1 - 2.5 9.1 26.1 81 4.2 14.5 3.0 2 1 1 3 3 2 0 cGMP-dependent protein kinase interacting domain Cep57_MT_bd PF06657.13 KXG54595.1 - 3.4 8.2 21.2 0.43 11.1 6.7 3.9 2 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Allexi_40kDa PF05549.11 KXG54595.1 - 3.9 6.9 5.5 9.2 5.7 3.9 2.2 1 1 0 1 1 1 0 Allexivirus 40kDa protein Chibby PF14645.6 KXG54595.1 - 4.1 7.8 12.5 32 5.0 0.3 3.1 1 1 1 2 2 2 0 Chibby family IFT57 PF10498.9 KXG54595.1 - 4.9 6.0 19.1 0.54 9.2 14.3 1.7 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Taxilin PF09728.9 KXG54595.1 - 5.1 6.2 25.6 0.36 10.0 17.3 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein CENP-F_leu_zip PF10473.9 KXG54595.1 - 8.6 6.4 30.6 15 5.6 17.6 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ACC_central PF08326.12 KXG54596.1 - 9.3e-279 926.7 0.0 1.2e-278 926.3 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KXG54596.1 - 8.1e-191 634.9 0.0 1.5e-190 634.0 0.0 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KXG54596.1 - 8.6e-53 179.0 0.0 1.8e-52 177.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KXG54596.1 - 4.7e-28 97.9 0.1 9.8e-28 96.9 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KXG54596.1 - 8.2e-24 83.8 0.0 9.8e-20 70.7 0.0 3.2 2 0 0 2 2 2 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KXG54596.1 - 1.8e-17 62.9 0.1 4.9e-17 61.5 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KXG54596.1 - 6.7e-05 22.5 0.0 0.00021 20.9 0.0 1.8 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KXG54596.1 - 0.00016 21.8 0.0 0.00062 19.8 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain GxGYxYP_N PF16216.5 KXG54596.1 - 0.0074 16.5 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal Biotin_lipoyl_2 PF13533.6 KXG54596.1 - 0.15 11.9 0.0 0.48 10.3 0.0 1.8 1 0 0 1 1 1 0 Biotin-lipoyl like ATPgrasp_Ter PF15632.6 KXG54596.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon MFS_1 PF07690.16 KXG54597.1 - 8.8e-31 107.1 68.2 1.2e-30 106.6 61.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily GMC_oxred_N PF00732.19 KXG54599.1 - 3.6e-68 230.1 0.0 5e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXG54599.1 - 5.1e-29 101.6 0.0 9.5e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXG54599.1 - 9e-06 25.0 0.1 1.4e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXG54599.1 - 9.1e-05 22.6 0.1 0.00034 20.8 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXG54599.1 - 0.00075 18.7 0.0 0.0036 16.4 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXG54599.1 - 0.00088 19.0 1.5 0.0029 17.2 1.1 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXG54599.1 - 0.002 17.4 0.0 0.0046 16.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXG54599.1 - 0.0079 15.5 0.2 0.053 12.7 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXG54599.1 - 0.011 15.0 0.2 0.14 11.4 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXG54599.1 - 0.039 12.7 0.1 0.077 11.7 0.1 1.4 2 0 0 2 2 2 0 HI0933-like protein F-box-like PF12937.7 KXG54600.1 - 1.8e-07 30.9 0.2 8.9e-07 28.7 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXG54600.1 - 0.024 14.5 0.1 0.08 12.9 0.0 1.9 2 0 0 2 2 2 0 F-box domain SRR1 PF07985.12 KXG54601.1 - 0.0012 18.8 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 SRR1 Codanin-1_C PF15296.6 KXG54601.1 - 1 9.4 2.7 3.3 7.8 0.2 2.2 2 0 0 2 2 2 0 Codanin-1 C-terminus HeLo PF14479.6 KXG54602.1 - 0.00024 21.0 0.4 0.012 15.5 0.4 2.4 1 1 0 1 1 1 1 Prion-inhibition and propagation Peptidase_S64 PF08192.11 KXG54602.1 - 0.052 12.0 0.0 0.15 10.5 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S64 RINGv PF12906.7 KXG54603.1 - 7.9e-16 57.9 11.0 1.3e-15 57.2 11.0 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KXG54603.1 - 0.019 15.3 10.1 0.033 14.5 10.1 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 KXG54603.1 - 0.4 10.5 5.9 0.67 9.8 5.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KXG54603.1 - 1.2 9.1 5.8 2.6 8.0 5.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KXG54603.1 - 1.5 9.1 6.9 2.9 8.2 6.9 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain DUF5344 PF17279.2 KXG54604.1 - 0.71 10.5 4.0 1.3 9.6 0.3 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5344) DUF2884 PF11101.8 KXG54604.1 - 2.5 7.5 5.2 5.8 6.3 0.1 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2884) ApoO PF09769.9 KXG54604.1 - 4.2 7.3 5.8 8.8 6.3 0.2 3.9 4 0 0 4 4 4 0 Apolipoprotein O TMEM208_SND2 PF05620.11 KXG54605.1 - 9e-57 191.5 0.0 1e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Peptidase_A24 PF01478.18 KXG54605.1 - 0.15 12.5 2.4 0.25 11.8 0.3 1.9 2 0 0 2 2 2 0 Type IV leader peptidase family TPR_1 PF00515.28 KXG54606.1 - 5.4e-45 149.4 21.7 4.8e-08 32.5 0.0 9.8 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 KXG54606.1 - 6.2e-41 135.2 20.9 1.8e-05 24.5 0.3 10.3 10 0 0 10 10 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KXG54606.1 - 6.9e-29 99.9 22.4 8.4e-22 77.2 2.4 4.5 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KXG54606.1 - 5.6e-27 91.7 9.3 0.0022 18.1 0.0 9.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 KXG54606.1 - 2.2e-22 79.3 19.9 2.4e-08 34.4 0.6 8.3 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 KXG54606.1 - 6.9e-22 77.8 23.0 0.00043 20.9 1.5 8.2 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 KXG54606.1 - 9.4e-22 76.4 13.3 4e-05 23.2 2.5 9.8 7 3 2 9 9 9 5 TPR repeat TPR_14 PF13428.6 KXG54606.1 - 3.5e-19 67.9 10.1 0.094 13.6 0.0 9.2 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 KXG54606.1 - 8.2e-17 61.3 17.3 0.013 15.8 0.0 7.9 5 1 3 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 KXG54606.1 - 4.7e-13 48.2 3.5 0.0063 16.5 0.0 8.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXG54606.1 - 2e-12 46.6 16.8 0.064 13.7 0.0 8.5 10 0 0 10 10 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 KXG54606.1 - 3.6e-08 33.5 10.0 2.8 8.8 0.1 8.4 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXG54606.1 - 1.2e-05 25.0 0.4 8 6.5 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXG54606.1 - 1.9e-05 24.7 4.0 12 6.1 0.1 6.0 3 1 4 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.9 KXG54606.1 - 0.013 15.2 9.0 0.27 10.9 1.4 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain ChAPs PF09295.10 KXG54606.1 - 0.18 10.8 0.7 17 4.3 0.2 2.4 1 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Sel1 PF08238.12 KXG54606.1 - 0.22 12.3 2.5 82 4.1 0.0 5.2 6 0 0 6 6 5 0 Sel1 repeat APP_E2 PF12925.7 KXG54606.1 - 0.42 10.3 2.3 0.79 9.4 0.3 2.4 3 0 0 3 3 3 0 E2 domain of amyloid precursor protein MIT PF04212.18 KXG54606.1 - 3.7 7.7 5.0 13 6.0 0.3 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Acyltransferase PF01553.21 KXG54607.1 - 8.3e-32 109.6 0.0 1.4e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ACPS PF01648.20 KXG54608.1 - 1e-12 48.2 0.0 4.2e-12 46.2 0.0 2.1 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.19 KXG54609.1 - 9.2e-55 185.4 0.0 7.6e-45 153.1 0.0 2.1 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KXG54609.1 - 9.7e-10 38.4 0.0 3.3e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KXG54609.1 - 0.00065 19.5 0.0 0.0045 16.8 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KXG54609.1 - 0.012 15.5 0.0 0.031 14.1 0.0 1.6 2 0 0 2 2 2 0 DJ-1/PfpI family Peptidase_S51 PF03575.17 KXG54609.1 - 0.012 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 GATase_5 PF13507.6 KXG54609.1 - 0.031 13.4 0.0 0.6 9.2 0.0 2.1 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain RRM_1 PF00076.22 KXG54610.1 - 8.2e-16 57.6 0.0 1.2e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cep57_CLD PF14073.6 KXG54611.1 - 0.0074 16.3 4.6 0.015 15.4 4.6 1.4 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 TACC_C PF05010.14 KXG54611.1 - 0.07 12.9 3.2 0.39 10.5 0.1 2.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BLOC1_2 PF10046.9 KXG54611.1 - 0.17 12.2 0.5 0.95 9.8 0.0 2.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 kleA_kleC PF17383.2 KXG54611.1 - 0.25 11.7 3.2 3.7 7.9 0.2 3.1 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Rotamase PF00639.21 KXG54614.1 - 5.8e-23 81.7 0.1 8.6e-23 81.1 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KXG54614.1 - 5e-14 52.8 0.0 7.3e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KXG54614.1 - 1.4e-09 37.9 5.0 1.5e-09 37.8 2.8 2.0 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KXG54614.1 - 0.00022 22.0 0.0 0.00041 21.2 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain RNA_POL_M_15KD PF02150.16 KXG54615.1 - 2.8e-11 43.1 1.6 2.8e-11 43.1 1.6 2.7 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit C1_1 PF00130.22 KXG54615.1 - 0.0044 16.9 6.1 0.74 9.8 0.6 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) GFA PF04828.14 KXG54615.1 - 0.0074 16.6 6.5 1.2 9.5 0.1 2.2 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme zf-CHY PF05495.12 KXG54615.1 - 5 7.7 12.5 1.9 9.0 7.7 2.3 1 1 2 3 3 3 0 CHY zinc finger eIF3g PF12353.8 KXG54615.1 - 6.7 7.1 7.0 0.2 12.1 1.0 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Ribosomal_L14 PF00238.19 KXG54616.1 - 8.2e-47 158.3 2.1 9.1e-47 158.1 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e FlgH PF02107.16 KXG54616.1 - 0.027 14.1 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein Phage_antitermQ PF06530.12 KXG54616.1 - 0.052 13.5 0.1 0.079 12.9 0.1 1.4 1 1 0 1 1 1 0 Phage antitermination protein Q DUF4777 PF16007.5 KXG54616.1 - 0.14 12.4 0.1 0.5 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) SET PF00856.28 KXG54617.1 - 6.3e-12 46.2 0.6 7.9e-10 39.4 0.0 2.9 3 1 0 3 3 3 2 SET domain FAM76 PF16046.5 KXG54617.1 - 0.021 14.2 4.4 0.63 9.3 0.7 2.5 2 0 0 2 2 2 0 FAM76 protein COesterase PF00135.28 KXG54618.1 - 1.4e-70 238.6 0.1 1.6e-70 238.4 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXG54618.1 - 0.00015 21.7 0.4 0.0013 18.6 0.4 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXG54618.1 - 0.031 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DEAD PF00270.29 KXG54619.1 - 1.4e-30 106.3 0.0 2.9e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXG54619.1 - 3e-19 69.4 1.6 3e-18 66.2 1.4 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXG54619.1 - 4.5e-06 26.8 0.0 4e-05 23.7 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PH PF00169.29 KXG54620.1 - 1.1e-07 32.4 0.0 3.1e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 PH domain Anillin PF08174.11 KXG54620.1 - 3.7e-06 27.4 0.0 1e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 Cell division protein anillin Pkinase PF00069.25 KXG54621.1 - 1.2e-29 103.5 0.0 2.8e-29 102.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG54621.1 - 1.6e-11 44.0 0.1 1.1e-10 41.2 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KXG54621.1 - 0.15 11.6 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 RIO1 family DUF829 PF05705.14 KXG54623.1 - 5.3e-49 167.3 0.0 6.1e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) GHL15 PF14885.6 KXG54623.1 - 0.065 13.2 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 adh_short PF00106.25 KXG54624.1 - 3.6e-22 78.8 0.2 8.4e-21 74.3 0.2 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG54624.1 - 8e-16 58.3 0.2 7.7e-15 55.1 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG54624.1 - 4.2e-05 23.5 0.8 9.6e-05 22.4 0.8 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXG54624.1 - 0.021 14.3 0.5 0.19 11.1 0.5 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3425 PF11905.8 KXG54625.1 - 1.1e-14 54.5 0.1 3.6e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) MFS_1 PF07690.16 KXG54626.1 - 9.6e-34 116.8 59.2 8.1e-33 113.8 59.2 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXG54626.1 - 1.4e-09 36.9 14.6 1.4e-09 36.9 14.6 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 KXG54627.1 - 8.4e-16 57.8 3.9 1.4e-13 50.5 3.9 2.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4047 PF13256.6 KXG54627.1 - 0.0037 17.4 0.6 0.68 10.1 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4047) Tmemb_cc2 PF10267.9 KXG54627.1 - 0.081 12.1 1.8 0.14 11.3 1.8 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Csm2_III-A PF03750.13 KXG54627.1 - 0.2 12.5 0.3 0.99 10.3 0.1 2.1 2 0 0 2 2 2 0 Csm2 Type III-A Glyco_hydro_43 PF04616.14 KXG54628.1 - 5.6e-35 121.0 3.8 7.3e-35 120.7 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Peroxin-3 PF04882.12 KXG54629.1 - 0.0056 15.7 2.5 0.0075 15.3 2.5 1.3 1 0 0 1 1 1 1 Peroxin-3 DNA_pol_A_exo1 PF01612.20 KXG54629.1 - 0.026 14.3 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 3'-5' exonuclease Cnd1_N PF12922.7 KXG54629.1 - 0.24 11.3 8.7 0.081 12.8 2.9 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term RPA43_OB PF17875.1 KXG54629.1 - 0.42 11.3 6.5 9.5 6.9 0.1 2.2 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Connexin PF00029.19 KXG54629.1 - 1.7 8.3 8.1 1.2 8.9 2.4 2.1 2 0 0 2 2 2 0 Connexin OrfB_IS605 PF01385.19 KXG54629.1 - 3.6 7.8 12.2 0.51 10.6 1.4 2.3 2 0 0 2 2 2 0 Probable transposase HA2 PF04408.23 KXG54629.1 - 4.4 7.6 5.7 2 8.7 0.7 2.1 2 0 0 2 2 2 0 Helicase associated domain (HA2) RNA_polI_A34 PF08208.11 KXG54629.1 - 5.8 6.9 22.1 0.4 10.7 16.0 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Peroxin-13_N PF04088.13 KXG54629.1 - 8.2 6.7 6.9 5.5 7.3 2.0 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Lipase_GDSL_2 PF13472.6 KXG54630.1 - 1.3e-10 41.9 0.3 2.5e-10 41.1 0.3 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXG54630.1 - 5.6e-08 33.0 0.0 7.1e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Acyl_transf_3 PF01757.22 KXG54631.1 - 3.6e-19 69.0 25.7 1.2e-18 67.3 25.7 1.9 1 1 0 1 1 1 1 Acyltransferase family DUF1624 PF07786.12 KXG54631.1 - 1.2e-05 25.0 0.8 0.0017 17.9 0.1 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1624) DUF202 PF02656.15 KXG54632.1 - 4.2e-15 55.9 2.3 4.2e-15 55.9 2.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Abhydrolase_9_N PF15420.6 KXG54632.1 - 0.16 11.9 5.3 0.24 11.4 5.3 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus GCV_T PF01571.21 KXG54633.1 - 5e-72 242.4 0.0 7.4e-72 241.8 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KXG54633.1 - 1.3e-45 156.6 0.5 1.8e-45 156.0 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 KXG54633.1 - 5.3e-19 67.9 0.1 1.5e-18 66.5 0.1 1.9 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 KXG54633.1 - 1.8e-18 66.6 0.0 3.2e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox_2 PF07992.14 KXG54633.1 - 8.6e-06 25.2 0.0 0.031 13.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXG54633.1 - 0.00014 22.3 0.0 0.032 14.8 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXG54633.1 - 0.002 18.1 0.2 0.27 11.2 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding TrkA_N PF02254.18 KXG54633.1 - 0.0022 18.3 0.3 0.009 16.3 0.1 2.1 3 0 0 3 3 3 1 TrkA-N domain Shikimate_DH PF01488.20 KXG54633.1 - 0.017 15.2 0.1 0.032 14.3 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KXG54633.1 - 0.02 14.2 0.5 0.32 10.2 0.5 2.1 1 1 0 1 1 1 0 FAD binding domain ThiF PF00899.21 KXG54633.1 - 0.02 14.3 0.1 0.033 13.5 0.1 1.2 1 0 0 1 1 1 0 ThiF family Trp_halogenase PF04820.14 KXG54633.1 - 0.099 11.5 0.1 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_8 PF13450.6 KXG54633.1 - 0.1 12.8 0.0 0.48 10.7 0.0 2.2 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SoxG PF04268.12 KXG54633.1 - 0.12 12.5 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family MFS_1 PF07690.16 KXG54634.1 - 8.7e-14 51.2 45.2 1.8e-12 46.9 43.9 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4203 PF13886.6 KXG54634.1 - 0.0035 17.0 9.3 0.0035 17.0 9.3 3.8 3 2 0 3 3 3 1 Domain of unknown function (DUF4203) DUF2530 PF10745.9 KXG54634.1 - 0.071 13.3 0.5 0.071 13.3 0.5 4.7 4 2 0 4 4 4 0 Protein of unknown function (DUF2530) Pox_A14 PF05767.12 KXG54634.1 - 0.16 12.1 4.0 0.39 10.9 0.2 3.3 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 OATP PF03137.20 KXG54634.1 - 6.9 4.8 11.9 2.1 6.6 4.5 2.5 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Sulfotransfer_3 PF13469.6 KXG54635.1 - 0.0015 19.0 0.0 0.0034 17.8 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family ERG4_ERG24 PF01222.17 KXG54636.1 - 3.1e-146 487.5 18.7 3.5e-146 487.3 18.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family p450 PF00067.22 KXG54637.1 - 2.8e-57 194.5 0.0 3.9e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DRAT PF07357.11 KXG54637.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) NAD_binding_4 PF07993.12 KXG54638.1 - 6e-27 94.4 0.0 8.1e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KXG54638.1 - 0.0098 14.9 0.0 0.045 12.7 0.0 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family TFIIE_alpha PF02002.17 KXG54639.1 - 1.4e-17 63.5 0.0 2.8e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit DUF1849 PF08904.11 KXG54639.1 - 0.026 14.1 0.6 0.053 13.1 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) DUF3944 PF13099.6 KXG54639.1 - 0.14 12.1 0.3 0.3 11.0 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) TF_Zn_Ribbon PF08271.12 KXG54639.1 - 0.34 10.5 1.8 1.2 8.7 1.8 2.0 1 1 0 1 1 1 0 TFIIB zinc-binding PseudoU_synth_1 PF01416.20 KXG54640.1 - 2.3e-12 47.3 0.0 2.2e-10 41.0 0.0 2.6 2 0 0 2 2 2 1 tRNA pseudouridine synthase YlbE PF14003.6 KXG54640.1 - 0.11 12.9 0.3 0.35 11.3 0.3 1.8 1 0 0 1 1 1 0 YlbE-like protein DUF3517 PF12030.8 KXG54641.1 - 6.1e-88 295.0 0.0 1.1e-87 294.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 KXG54641.1 - 8.7e-39 133.5 0.1 1.8e-38 132.5 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXG54641.1 - 2.4e-20 73.4 0.1 5.3e-20 72.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ADD_ATRX PF17981.1 KXG54641.1 - 0.15 11.9 0.1 0.45 10.4 0.1 1.7 1 0 0 1 1 1 0 Cysteine Rich ADD domain Hexapep PF00132.24 KXG54642.1 - 5.5e-12 44.9 14.7 2.8e-11 42.7 4.7 3.3 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXG54642.1 - 1.3e-11 44.1 12.3 1.6e-09 37.3 4.6 3.3 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 KXG54642.1 - 1.3e-11 44.5 0.3 2.1e-11 43.9 0.3 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase ICMT PF04140.14 KXG54643.1 - 2.6e-28 98.3 0.6 4.5e-28 97.5 0.6 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KXG54643.1 - 2.2e-10 40.9 2.2 2.2e-10 40.9 2.2 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KXG54643.1 - 1.6e-07 31.1 0.6 2.2e-07 30.7 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) WD40 PF00400.32 KXG54645.1 - 9.3e-31 105.4 28.6 2.5e-06 28.1 3.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXG54645.1 - 9.6e-17 61.1 0.4 0.00039 20.7 0.0 5.6 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXG54645.1 - 0.0024 17.8 0.1 0.94 9.3 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXG54645.1 - 0.036 12.7 0.7 3 6.4 0.1 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Frtz PF11768.8 KXG54645.1 - 0.061 11.6 0.0 0.19 10.0 0.0 1.6 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Bacteroid_pep PF14406.6 KXG54645.1 - 0.18 12.2 0.0 0.61 10.5 0.0 2.0 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes MBOAT PF03062.19 KXG54646.1 - 5.4e-27 95.1 14.7 9.4e-27 94.3 14.7 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MAPEG PF01124.18 KXG54646.1 - 7.8e-25 87.3 0.7 7.8e-25 87.3 0.7 3.0 3 0 0 3 3 3 1 MAPEG family MBOAT_2 PF13813.6 KXG54646.1 - 0.0068 16.7 2.4 0.02 15.1 2.4 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family OMPdecase PF00215.24 KXG54647.1 - 5.4e-77 258.4 0.0 6.4e-77 258.2 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MFS_1 PF07690.16 KXG54648.1 - 3.4e-37 128.2 25.4 7e-37 127.2 22.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXG54648.1 - 0.0028 16.6 4.0 0.0028 16.6 4.0 1.6 1 1 1 2 2 2 1 MFS_1 like family Saf_2TM PF18303.1 KXG54648.1 - 0.19 11.3 0.7 4.5 6.8 0.1 2.6 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain baeRF_family6 PF18848.1 KXG54649.1 - 0.1 13.0 0.0 0.29 11.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 6 S4 PF01479.25 KXG54650.1 - 4.1e-14 52.0 0.0 7.6e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KXG54650.1 - 3.4e-11 43.9 2.4 4.5e-11 43.5 2.4 1.4 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Occludin_ELL PF07303.13 KXG54650.1 - 0.047 14.4 0.3 0.14 12.9 0.1 1.9 1 1 1 2 2 2 0 Occludin homology domain Clr5 PF14420.6 KXG54651.1 - 1.8e-07 31.3 0.0 4.5e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Clr5 domain rve PF00665.26 KXG54651.1 - 6.7e-06 26.3 0.2 0.043 14.0 0.0 2.5 2 0 0 2 2 2 2 Integrase core domain Sigma54_DBD PF04552.13 KXG54651.1 - 0.00032 20.5 0.4 0.022 14.4 0.0 2.3 1 1 1 2 2 2 1 Sigma-54, DNA binding domain HTH_Tnp_Tc3_2 PF01498.18 KXG54651.1 - 0.0038 17.4 0.5 5.2 7.4 0.1 2.8 2 0 0 2 2 2 2 Transposase HTH_32 PF13565.6 KXG54651.1 - 0.0045 17.6 0.7 9.6 6.9 0.0 3.6 3 1 1 4 4 4 2 Homeodomain-like domain HTH_21 PF13276.6 KXG54651.1 - 0.0065 16.6 2.6 0.014 15.5 0.2 2.7 3 0 0 3 3 3 1 HTH-like domain HTH_33 PF13592.6 KXG54651.1 - 0.017 14.8 2.5 1.4 8.7 0.1 3.2 3 0 0 3 3 3 0 Winged helix-turn helix Arg_repressor PF01316.21 KXG54651.1 - 0.018 14.8 0.6 0.48 10.2 0.0 2.5 1 1 1 2 2 2 0 Arginine repressor, DNA binding domain HTH_12 PF08461.10 KXG54651.1 - 0.052 13.5 0.0 3.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain DDE_Tnp_ISAZ013 PF07592.11 KXG54651.1 - 0.09 11.7 0.6 0.34 9.9 0.1 2.0 1 1 1 2 2 2 0 Rhodopirellula transposase DDE domain SapB_2 PF03489.17 KXG54651.1 - 0.19 11.8 0.8 0.61 10.3 0.0 2.2 3 0 0 3 3 3 0 Saposin-like type B, region 2 ketoacyl-synt PF00109.26 KXG54652.1 - 3.7e-68 229.9 0.0 3.7e-67 226.5 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KXG54652.1 - 2.4e-62 210.8 0.0 4e-62 210.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KXG54652.1 - 1.9e-61 207.1 0.3 5.4e-61 205.6 0.3 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KXG54652.1 - 1.9e-44 152.5 0.0 3.4e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXG54652.1 - 4.4e-32 110.6 0.0 9.8e-32 109.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KXG54652.1 - 1.3e-20 74.0 0.0 4.1e-18 65.9 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXG54652.1 - 5.4e-14 52.6 0.0 1.4e-10 41.6 0.0 2.8 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KXG54652.1 - 2.3e-11 44.2 0.0 6.2e-10 39.7 0.0 3.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXG54652.1 - 3.6e-11 43.2 0.0 9e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXG54652.1 - 5.6e-11 42.5 0.0 4.5e-10 39.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KXG54652.1 - 8.6e-11 43.0 0.1 9e-10 39.7 0.0 2.8 3 0 0 3 3 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXG54652.1 - 4.7e-10 39.2 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KXG54652.1 - 1.7e-09 37.7 0.0 5.3e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 KXG54652.1 - 1.7e-08 35.0 0.0 8.2e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 KXG54652.1 - 1.2e-06 28.8 0.1 3.2e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site NodS PF05401.11 KXG54652.1 - 1.5e-05 24.7 0.0 4.9e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Nodulation protein S (NodS) Thiolase_N PF00108.23 KXG54652.1 - 0.00028 20.3 0.0 0.0007 19.0 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KXG54652.1 - 0.0014 18.1 0.0 0.0031 16.9 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 KXG54652.1 - 0.02 14.6 0.0 0.059 13.0 0.0 1.8 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.9 KXG54652.1 - 0.025 14.3 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase DnaJ PF00226.31 KXG54653.1 - 8.5e-25 86.7 1.8 1.5e-24 85.9 1.8 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KXG54653.1 - 1.4e-24 86.9 0.0 2e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KXG54653.1 - 1.6e-15 57.2 15.1 2.7e-15 56.5 15.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KXG54653.1 - 2.5e-06 27.3 5.6 0.012 15.5 0.5 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KXG54653.1 - 0.027 14.5 7.7 1.6 8.8 2.0 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 KXG54653.1 - 0.15 11.7 9.1 0.18 11.4 0.9 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Lar_restr_allev PF14354.6 KXG54653.1 - 0.44 11.0 10.2 2.8 8.4 1.7 3.0 1 1 2 3 3 3 0 Restriction alleviation protein Lar DUF4449 PF14613.6 KXG54654.1 - 6.5e-07 29.6 0.8 6.5e-07 29.6 0.8 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF4449) Tricorn_C1 PF14684.6 KXG54654.1 - 0.00051 20.1 0.2 0.015 15.3 0.1 3.1 3 0 0 3 3 3 1 Tricorn protease C1 domain Sec34 PF04136.15 KXG54654.1 - 0.035 14.0 1.2 0.14 12.0 0.1 2.5 2 1 1 3 3 3 0 Sec34-like family PKHD_C PF18331.1 KXG54654.1 - 0.079 13.0 0.6 2.3 8.3 0.1 3.2 3 0 0 3 3 3 0 PKHD-type hydroxylase C-terminal domain AKNA PF12443.8 KXG54654.1 - 0.18 12.4 1.1 6.9 7.4 0.1 2.8 2 0 0 2 2 2 0 AT-hook-containing transcription factor Malic_M PF03949.15 KXG54655.1 - 2.7e-91 305.4 0.0 3.5e-91 305.0 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KXG54655.1 - 1.5e-63 213.9 0.0 3e-63 212.9 0.0 1.5 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Oxidored_FMN PF00724.20 KXG54656.1 - 1.8e-46 159.0 0.0 2.3e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KXG54656.1 - 0.00038 20.0 0.0 0.038 13.4 0.0 2.2 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel Fungal_trans PF04082.18 KXG54657.1 - 1.3e-21 76.9 0.0 2.5e-21 75.9 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXG54657.1 - 7e-07 29.3 6.8 1.4e-06 28.3 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXG54658.1 - 1.3e-31 109.6 1.0 2.1e-31 108.9 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXG54659.1 - 2.6e-48 164.7 47.7 1e-45 156.2 49.1 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXG54659.1 - 7.4e-15 54.4 24.0 2.5e-14 52.7 23.2 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXG54659.1 - 9.3e-10 37.9 13.6 9.3e-10 37.9 13.6 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter DBD_Tnp_Mut PF03108.15 KXG54660.1 - 3.9e-08 33.2 1.7 6.8e-08 32.4 1.7 1.3 1 0 0 1 1 1 1 MuDR family transposase THOC7 PF05615.13 KXG54661.1 - 4.3e-43 146.8 5.9 4.3e-43 146.8 5.9 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 Peroxin-13_N PF04088.13 KXG54661.1 - 0.16 12.3 0.4 0.46 10.8 0.3 1.8 1 1 0 1 1 1 0 Peroxin 13, N-terminal region Mod_r PF07200.13 KXG54661.1 - 0.21 11.7 13.2 0.069 13.3 9.2 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FUSC PF04632.12 KXG54661.1 - 2 6.9 6.9 2.8 6.4 6.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4600 PF15372.6 KXG54661.1 - 6.5 7.2 12.3 1.4 9.4 8.5 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) TBCA PF02970.16 KXG54662.1 - 4.7e-23 81.3 7.6 4.7e-23 81.3 7.6 1.2 1 1 0 1 1 1 1 Tubulin binding cofactor A Elongin_A PF06881.11 KXG54663.1 - 2e-25 89.3 0.0 3.9e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A SOG2 PF10428.9 KXG54663.1 - 2 7.5 23.8 3.1 6.9 23.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 KXG54663.1 - 9.3 6.1 13.8 14 5.5 13.8 1.3 1 0 0 1 1 1 0 SPX domain ubiquitin PF00240.23 KXG54664.1 - 1.5e-18 66.3 0.0 4.1e-18 64.9 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXG54664.1 - 4e-07 29.8 0.0 1e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L44 PF00935.19 KXG54665.1 - 3.4e-35 120.4 12.9 6.8e-35 119.4 12.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L44 LigT_PEase PF02834.16 KXG54665.1 - 0.013 15.6 0.0 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 LigT like Phosphoesterase Sugar_tr PF00083.24 KXG54666.1 - 1.9e-82 277.6 31.1 2.1e-82 277.4 31.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXG54666.1 - 2.5e-27 95.7 27.6 9.4e-27 93.8 26.0 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KXG54667.1 - 1.8e-12 46.9 0.1 3.3e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4449 PF14613.6 KXG54667.1 - 0.014 15.5 1.0 6.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) REC114-like PF15165.6 KXG54667.1 - 0.07 12.9 2.5 0.11 12.2 2.5 1.2 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Acetyltransf_1 PF00583.25 KXG54668.1 - 3e-06 27.5 0.0 3.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXG54668.1 - 0.00031 21.1 0.0 0.00045 20.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXG54668.1 - 0.0094 15.9 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.25 KXG54668.1 - 0.2 11.8 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MFS_1 PF07690.16 KXG54670.1 - 0.0016 17.5 6.0 0.0025 16.8 6.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF981 PF06168.11 KXG54670.1 - 0.035 14.0 0.8 0.046 13.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF981) MFS_1_like PF12832.7 KXG54670.1 - 0.068 12.0 0.5 0.17 10.7 0.5 1.5 1 1 0 1 1 1 0 MFS_1 like family Phosphoesterase PF04185.14 KXG54672.1 - 1.7e-64 218.2 1.5 3.8e-64 217.1 1.5 1.5 1 1 0 1 1 1 1 Phosphoesterase family DUF3824 PF12868.7 KXG54673.1 - 4.9e-32 111.6 31.9 4.9e-32 111.6 31.9 9.5 5 2 3 8 8 8 4 Domain of unknwon function (DUF3824) Miga PF10265.9 KXG54673.1 - 0.38 9.7 3.8 19 4.1 3.9 2.5 2 0 0 2 2 2 0 Mitoguardin Vac7 PF12751.7 KXG54674.1 - 8.2e-155 515.9 2.4 8.2e-155 515.9 2.4 2.1 2 1 0 2 2 2 1 Vacuolar segregation subunit 7 CorA PF01544.18 KXG54675.1 - 1.2e-37 129.8 0.0 2.5e-37 128.8 0.0 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein UPF0261 PF06792.11 KXG54676.1 - 1.1e-70 238.7 0.0 1.5e-36 126.3 0.0 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0261) PEP_hydrolase PF09370.10 KXG54677.1 - 2.4e-134 446.6 1.2 2.7e-134 446.5 1.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NMO PF03060.15 KXG54677.1 - 0.0018 17.7 3.4 0.0032 16.9 0.1 2.0 2 0 0 2 2 2 1 Nitronate monooxygenase S-methyl_trans PF02574.16 KXG54677.1 - 0.023 14.5 0.1 0.045 13.6 0.1 1.3 1 1 0 1 1 1 0 Homocysteine S-methyltransferase FlaC_arch PF05377.11 KXG54678.1 - 1.2 9.5 5.3 1.9 8.9 0.9 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FSA_C PF10479.9 KXG54678.1 - 4.7 5.2 12.9 11 4.0 12.9 1.5 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus TSC22 PF01166.18 KXG54678.1 - 8.6 6.8 6.9 2.9 8.3 0.4 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family adh_short PF00106.25 KXG54679.1 - 4.5e-38 130.7 0.2 6.9e-38 130.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXG54679.1 - 1.8e-26 93.1 0.0 2.5e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXG54679.1 - 6.8e-07 29.4 2.9 2.6e-05 24.2 2.5 2.8 1 1 1 2 2 2 1 KR domain MFS_1 PF07690.16 KXG54680.1 - 0.022 13.7 29.7 0.036 13.0 25.5 2.8 2 1 0 2 2 2 0 Major Facilitator Superfamily PDR_assoc PF08370.11 KXG54680.1 - 6.8 6.5 6.9 20 5.0 0.3 3.4 3 0 0 3 3 3 0 Plant PDR ABC transporter associated SLATT_4 PF18186.1 KXG54681.1 - 3.6e-05 23.5 0.0 0.19 11.4 0.0 2.9 1 1 3 4 4 4 3 SMODS and SLOG-associating 2TM effector domain family 4 partial_CstF PF15861.5 KXG54681.1 - 0.00034 20.3 2.1 72 3.3 0.0 5.0 1 1 4 5 5 5 0 Partial cleavage stimulation factor domain Takusan PF04822.13 KXG54681.1 - 0.0011 18.9 1.0 41 4.1 0.1 4.6 1 1 3 4 4 4 0 Takusan Cornifin PF02389.15 KXG54681.1 - 0.0014 18.8 0.5 0.25 11.6 0.2 2.2 1 1 1 2 2 2 2 Cornifin (SPRR) family DSL PF01414.19 KXG54681.1 - 0.0018 18.5 15.4 9.7 6.6 0.1 5.1 1 1 5 6 6 6 3 Delta serrate ligand DFF40 PF09230.10 KXG54681.1 - 0.0091 15.6 10.9 10 5.7 0.3 5.1 1 1 5 6 6 6 1 DNA fragmentation factor 40 kDa DUF1986 PF09342.11 KXG54681.1 - 0.024 15.0 6.3 60 4.1 0.2 4.6 1 1 4 5 5 5 0 Domain of unknown function (DUF1986) V4R PF02830.18 KXG54681.1 - 0.027 14.5 21.4 17 5.5 0.1 6.0 1 1 5 6 6 6 0 V4R domain MF_alpha_N PF05436.11 KXG54681.1 - 0.033 14.1 0.2 0.058 13.3 0.2 1.4 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Metallophos_3 PF14582.6 KXG54681.1 - 0.22 10.8 0.3 25 4.0 0.1 2.2 1 1 2 3 3 3 0 Metallophosphoesterase, calcineurin superfamily Opiods_neuropep PF01160.18 KXG54681.1 - 0.92 9.7 11.3 51 4.1 0.1 5.0 1 1 5 6 6 6 0 Vertebrate endogenous opioids neuropeptide DUF2594 PF10769.9 KXG54681.1 - 0.97 9.5 8.2 2.3e+02 1.9 0.0 5.1 6 0 0 6 6 6 0 Protein of unknown function (DUF2594) DUF3585 PF12130.8 KXG54681.1 - 1.2 9.2 11.1 1.2e+02 2.8 0.1 4.8 1 1 4 5 5 5 0 Bivalent Mical/EHBP Rab binding domain Asparaginase_2 PF01112.18 KXG54682.1 - 8.4e-76 254.9 3.6 1.2e-75 254.4 3.6 1.2 1 0 0 1 1 1 1 Asparaginase AAA_18 PF13238.6 KXG54683.1 - 1.7e-05 25.4 0.2 0.00021 21.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain Beta_protein PF14350.6 KXG54683.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Beta protein MFS_1 PF07690.16 KXG54684.1 - 5.3e-20 71.6 51.9 5.3e-20 71.6 51.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily tRNA-synt_2 PF00152.20 KXG54685.1 - 5.6e-24 84.8 0.0 7.2e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KXG54685.1 - 0.00048 19.7 0.0 0.87 9.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) TruB_C_2 PF16198.5 KXG54685.1 - 0.16 12.2 0.0 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain Zn_clus PF00172.18 KXG54686.1 - 4.4e-10 39.5 11.6 4.4e-10 39.5 11.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha_GJ PF03229.13 KXG54688.1 - 0.024 15.2 4.6 0.024 15.2 4.6 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J Gcn1_N PF12074.8 KXG54689.1 - 8.9e-122 406.8 4.6 8.8e-121 403.5 0.6 3.1 2 0 0 2 2 2 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Ribosomal_L19e PF01280.20 KXG54689.1 - 1.6e-58 196.9 6.2 5e-58 195.3 6.2 1.9 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT PF02985.22 KXG54689.1 - 9.8e-28 93.8 34.1 0.45 10.9 0.0 21.7 25 0 0 25 25 22 7 HEAT repeat HEAT_2 PF13646.6 KXG54689.1 - 1.4e-20 73.5 42.5 6.7e-06 26.4 2.4 13.8 9 2 4 14 14 13 6 HEAT repeats HEAT_EZ PF13513.6 KXG54689.1 - 6.5e-20 71.2 58.6 9.4e-05 22.8 0.1 20.7 21 4 3 24 24 22 8 HEAT-like repeat Cnd1 PF12717.7 KXG54689.1 - 3e-15 56.6 2.3 0.033 14.2 0.1 9.1 8 1 2 10 10 10 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXG54689.1 - 3.2e-10 40.5 0.0 7.2 7.3 0.1 8.0 6 2 1 8 8 8 1 Vacuolar 14 Fab1-binding region ParcG PF10274.9 KXG54689.1 - 2.4e-09 37.6 1.0 0.043 13.9 0.0 5.9 6 1 0 6 6 5 2 Parkin co-regulated protein TIP120 PF08623.10 KXG54689.1 - 3.3e-06 27.0 0.7 0.0059 16.4 0.0 5.2 5 1 1 6 6 6 1 TATA-binding protein interacting (TIP20) CLASP_N PF12348.8 KXG54689.1 - 3.7e-06 26.7 0.0 0.24 10.9 0.0 5.9 4 1 1 5 5 5 1 CLASP N terminal IFRD PF05004.13 KXG54689.1 - 1.9e-05 23.9 14.2 0.055 12.6 1.3 5.4 4 1 1 5 5 5 3 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 KXG54689.1 - 0.0014 17.3 13.9 0.95 7.9 1.5 7.2 5 2 1 7 7 7 1 Adaptin N terminal region MMS19_C PF12460.8 KXG54689.1 - 0.0017 17.6 17.7 0.68 9.0 0.1 7.2 8 0 0 8 8 8 2 RNAPII transcription regulator C-terminal DUF937 PF06078.11 KXG54689.1 - 0.0022 18.6 6.5 17 6.0 0.0 6.7 6 1 0 6 6 6 0 Bacterial protein of unknown function (DUF937) Tti2 PF10521.9 KXG54689.1 - 0.0036 16.9 0.7 4.5 6.7 0.0 5.3 5 0 0 5 5 5 1 Tti2 family FANCI_S2 PF14676.6 KXG54689.1 - 0.012 15.9 0.3 0.33 11.3 0.0 3.7 3 0 0 3 3 2 0 FANCI solenoid 2 TFCD_C PF12612.8 KXG54689.1 - 0.98 9.2 3.2 8 6.2 0.0 4.1 5 0 0 5 5 5 0 Tubulin folding cofactor D C terminal Cohesin_HEAT PF12765.7 KXG54689.1 - 1.3 9.4 3.5 12 6.3 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion HA2 PF04408.23 KXG54690.1 - 1.3e-16 60.8 0.0 5.2e-16 58.9 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXG54690.1 - 2.6e-15 56.7 0.2 2.4e-14 53.6 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXG54690.1 - 4.5e-11 42.8 0.0 9.5e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXG54690.1 - 1.1e-05 25.7 0.1 5.4e-05 23.5 0.1 2.2 1 0 0 1 1 1 1 AAA domain KilA-N PF04383.13 KXG54691.1 - 0.0003 20.6 0.0 0.0077 16.1 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain BRCT_2 PF16589.5 KXG54692.1 - 1.8e-06 28.3 0.0 4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KXG54692.1 - 0.00067 19.9 0.0 0.0021 18.3 0.0 1.8 1 1 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 KXG54692.1 - 0.0035 17.2 1.6 0.05 13.5 0.0 2.4 2 0 0 2 2 2 1 twin BRCT domain FAM220 PF15487.6 KXG54692.1 - 0.031 13.9 0.2 0.04 13.5 0.2 1.1 1 0 0 1 1 1 0 FAM220 family Mg_trans_NIPA PF05653.14 KXG54693.1 - 1.3e-89 300.3 26.7 1.8e-89 299.8 26.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXG54693.1 - 1.5e-05 25.2 6.0 1.5e-05 25.2 6.0 3.3 3 0 0 3 3 3 1 EamA-like transporter family DUF1894 PF08979.11 KXG54693.1 - 0.071 13.5 0.3 10 6.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1894) DUF805 PF05656.14 KXG54693.1 - 4.7 7.7 12.5 2.6 8.5 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Patatin PF01734.22 KXG54694.1 - 9.9e-16 58.5 0.0 2.7e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase SHMT PF00464.19 KXG54695.1 - 6.5e-198 657.2 0.0 8.4e-198 656.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase MOSC PF03473.17 KXG54695.1 - 9.3e-36 122.7 0.0 3.1e-35 121.1 0.0 1.9 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 KXG54695.1 - 7.4e-12 45.2 0.0 1.7e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain BCD PF15461.6 KXG54695.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase Flocculin_t3 PF13928.6 KXG54696.1 - 0.013 16.0 5.9 0.013 16.0 5.9 3.7 1 1 2 3 3 3 0 Flocculin type 3 repeat MerB PF03243.15 KXG54697.1 - 0.039 14.1 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 Alkylmercury lyase FA_hydroxylase PF04116.13 KXG54698.1 - 1.5e-23 83.6 10.4 1.5e-23 83.6 10.4 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF5530 PF17670.1 KXG54699.1 - 0.014 15.2 0.2 0.023 14.5 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5530) AMP-binding PF00501.28 KXG54700.1 - 1.2e-74 251.4 0.0 1.6e-74 251.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KXG54700.1 - 6.1e-16 58.1 0.3 2e-15 56.4 0.3 2.0 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KXG54700.1 - 2.7e-14 53.9 0.1 9.5e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ras PF00071.22 KXG54701.1 - 1.3e-51 174.4 0.8 7.3e-51 172.0 0.8 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXG54701.1 - 1.5e-18 67.2 0.1 1.9e-17 63.6 0.1 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXG54701.1 - 0.00051 19.5 0.1 0.0041 16.6 0.1 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.18 KXG54701.1 - 0.0092 15.5 0.2 0.22 11.1 0.0 2.5 2 1 1 3 3 3 1 Ferrous iron transport protein B SRPRB PF09439.10 KXG54701.1 - 0.021 14.3 0.0 0.68 9.3 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KXG54701.1 - 0.079 12.9 0.0 9.1 6.2 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 KXG54701.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_25 PF13481.6 KXG54701.1 - 0.13 11.8 0.1 0.32 10.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KXG54701.1 - 0.15 11.5 0.0 6.5 6.3 0.0 2.7 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain DUF1749 PF08538.10 KXG54702.1 - 3.6e-96 321.8 0.0 4.3e-96 321.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KXG54702.1 - 6.5e-05 23.6 0.3 8.7e-05 23.2 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2164 PF09932.9 KXG54702.1 - 0.18 11.9 0.2 0.37 10.9 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) Mcp5_PH PF12814.7 KXG54703.1 - 4.2e-41 139.9 0.3 4.7e-21 75.2 0.2 2.7 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.12 KXG54703.1 - 0.00016 21.8 14.9 0.0022 18.1 6.8 2.4 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KXG54703.1 - 0.00085 19.8 11.4 0.00085 19.8 11.4 1.5 1 1 0 1 1 1 1 Fez1 GAS PF13851.6 KXG54703.1 - 0.054 12.8 11.6 0.16 11.3 11.6 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 KXG54703.1 - 0.21 11.0 11.0 0.36 10.3 11.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 KXG54703.1 - 0.36 11.0 1.9 12 6.1 0.4 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 KXG54703.1 - 1.2 9.2 6.1 2.2 8.3 6.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 KXG54703.1 - 2.7 8.1 12.9 0.92 9.5 2.8 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 KXG54703.1 - 5.3 6.9 5.4 15 5.4 0.0 3.1 1 1 2 3 3 3 0 Septum formation initiator Cyt-b5 PF00173.28 KXG54704.1 - 7e-22 77.4 0.1 7.9e-22 77.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 KXG54704.1 - 0.11 12.7 0.0 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 V-ATPase subunit H OB_NTP_bind PF07717.16 KXG54705.1 - 4.8e-21 74.9 0.0 1.4e-20 73.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KXG54705.1 - 1.6e-19 70.2 0.0 1.6e-19 70.2 0.0 3.3 4 1 0 4 4 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXG54705.1 - 5.4e-13 49.3 0.0 1.1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXG54705.1 - 2.2e-07 30.8 0.2 6.3e-07 29.3 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KXG54705.1 - 6.2e-05 22.8 0.0 0.0002 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXG54705.1 - 0.00013 21.1 0.0 0.0003 20.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KXG54705.1 - 0.00017 21.8 0.0 0.00076 19.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXG54705.1 - 0.00018 21.9 0.1 0.0004 20.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KXG54705.1 - 0.015 15.4 0.0 0.049 13.8 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain PWI PF01480.17 KXG54705.1 - 0.022 15.0 0.0 0.058 13.7 0.0 1.7 1 0 0 1 1 1 0 PWI domain SRP54 PF00448.22 KXG54705.1 - 0.042 13.5 0.2 0.11 12.1 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 KXG54705.1 - 0.071 13.6 0.0 0.071 13.6 0.0 3.7 2 1 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KXG54705.1 - 0.1 12.0 0.5 3.3 7.0 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Flavi_DEAD PF07652.14 KXG54705.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Pkinase PF00069.25 KXG54706.1 - 5.2e-40 137.5 0.0 1.2e-38 133.0 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG54706.1 - 2.6e-23 82.7 0.0 4.9e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase X PF00739.19 KXG54706.1 - 0.13 12.4 0.7 0.33 11.1 0.7 1.7 1 0 0 1 1 1 0 Trans-activation protein X Condensation PF00668.20 KXG54707.1 - 1.3e-206 686.7 0.0 4.8e-45 154.1 0.0 6.5 6 1 0 6 6 6 6 Condensation domain AMP-binding PF00501.28 KXG54707.1 - 3.4e-187 622.2 0.0 3.3e-82 276.3 0.0 3.5 3 1 0 3 3 3 3 AMP-binding enzyme PP-binding PF00550.25 KXG54707.1 - 2.7e-52 175.0 15.7 1.4e-10 41.4 0.1 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXG54707.1 - 2.7e-07 31.5 0.1 0.001 20.0 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 KXG54707.1 - 2.5e-05 24.2 0.8 6.4 6.5 0.0 4.8 4 0 0 4 4 4 3 Wax ester synthase-like Acyl-CoA acyltransferase domain K_oxygenase PF13434.6 KXG54708.1 - 1.3e-110 369.7 0.0 1.6e-110 369.5 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXG54708.1 - 1.1e-05 24.9 0.3 0.00064 19.1 0.0 2.7 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXG54708.1 - 1.4e-05 24.4 0.0 0.00053 19.3 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DHHC PF01529.20 KXG54709.1 - 5.5e-35 120.4 7.7 5.5e-35 120.4 7.7 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KXG54709.1 - 2.6e-27 95.2 0.1 1e-12 48.4 0.0 3.9 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXG54709.1 - 2.1e-24 85.2 3.8 1e-06 28.9 0.0 4.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXG54709.1 - 3.4e-21 73.1 1.6 3.3e-07 30.1 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 KXG54709.1 - 1.7e-18 66.1 0.8 2.1e-06 27.9 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KXG54709.1 - 1.2e-17 64.0 1.2 2.1e-06 28.2 0.2 4.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) TSC22 PF01166.18 KXG54711.1 - 0.97 9.8 10.1 1.7 9.0 0.4 3.8 3 1 0 3 3 3 0 TSC-22/dip/bun family SPOB_ab PF14682.6 KXG54711.1 - 4.8 7.3 6.4 9.1 6.4 0.0 3.0 3 0 0 3 3 3 0 Sporulation initiation phospho-transferase B, C-terminal Cyclin PF08613.11 KXG54712.1 - 1.6e-35 122.9 0.0 2.2e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXG54712.1 - 0.0016 18.2 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Na_Ca_ex PF01699.24 KXG54713.1 - 7.8e-24 84.4 28.2 2.3e-13 50.4 10.2 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3185 PF11381.8 KXG54713.1 - 0.069 13.2 1.4 0.28 11.2 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3185) PALP PF00291.25 KXG54714.1 - 1.9e-66 224.5 0.0 2.5e-66 224.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KXG54714.1 - 5.3e-11 42.8 0.0 8.1e-08 32.6 0.0 3.0 3 0 0 3 3 3 2 CBS domain SRPRB PF09439.10 KXG54715.1 - 2.3e-23 82.6 3.0 1e-21 77.2 3.0 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KXG54715.1 - 0.00011 21.7 0.1 0.0015 18.0 0.0 2.3 2 1 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXG54715.1 - 0.00015 21.8 0.1 0.00027 21.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KXG54715.1 - 0.01 15.6 0.8 0.026 14.3 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 KXG54715.1 - 0.013 15.3 0.0 0.61 9.8 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KXG54715.1 - 0.015 15.7 0.2 0.032 14.6 0.1 1.7 1 1 1 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 KXG54715.1 - 0.018 14.8 0.0 0.86 9.3 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 KXG54715.1 - 0.045 13.6 0.7 0.4 10.6 0.3 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KXG54715.1 - 0.046 14.0 0.5 0.16 12.2 0.5 1.9 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KXG54715.1 - 0.067 13.7 0.1 0.13 12.8 0.1 1.7 1 1 0 1 1 1 0 ABC transporter KRE9 PF05390.11 KXG54716.1 - 1.7e-08 35.1 8.3 1.9e-08 35.0 7.4 1.6 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 AA_kinase PF00696.28 KXG54717.1 - 7.8e-39 133.7 0.6 1e-38 133.3 0.6 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KXG54717.1 - 3e-16 59.2 0.1 3e-15 55.9 0.0 2.3 2 0 0 2 2 2 1 PUA domain Peptidase_M76 PF09768.9 KXG54718.1 - 2.3e-74 248.9 2.4 2.7e-74 248.6 2.4 1.1 1 0 0 1 1 1 1 Peptidase M76 family HNH_5 PF14279.6 KXG54718.1 - 0.017 15.0 1.1 0.099 12.5 0.1 2.4 2 0 0 2 2 2 0 HNH endonuclease SprT-like PF10263.9 KXG54718.1 - 0.12 12.2 3.9 0.071 13.0 1.4 1.8 1 1 1 2 2 2 0 SprT-like family Peptidase_M91 PF14891.6 KXG54718.1 - 0.27 11.5 0.8 0.44 10.8 0.8 1.5 1 1 0 1 1 1 0 Effector protein Pkinase PF00069.25 KXG54719.1 - 9e-72 241.6 0.0 1.3e-71 241.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXG54719.1 - 1.1e-43 149.3 0.0 1.5e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXG54719.1 - 4.3e-08 32.8 0.0 1.7e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXG54719.1 - 8.1e-05 22.1 0.2 0.00014 21.3 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXG54719.1 - 0.0072 15.3 0.0 0.0072 15.3 0.0 1.4 2 0 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 KXG54719.1 - 0.054 13.1 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KXG54719.1 - 0.065 13.1 0.1 0.093 12.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KXG54719.1 - 0.083 12.5 0.0 0.23 11.1 0.0 1.7 1 1 1 2 2 2 0 RIO1 family TIP41 PF04176.13 KXG54720.1 - 1.2e-70 236.5 0.0 1.4e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Ubiq_cyt_C_chap PF03981.12 KXG54721.1 - 6.1e-37 126.8 0.1 3.1e-36 124.5 0.1 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone Peptidase_M1 PF01433.20 KXG54722.1 - 1e-45 156.0 0.3 1.5e-45 155.5 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KXG54722.1 - 2.5e-35 121.0 0.0 4.9e-35 120.0 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KXG54722.1 - 1.6e-29 103.4 0.0 2.5e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KXG54722.1 - 0.0061 16.3 0.0 0.21 11.2 0.1 2.3 2 0 0 2 2 2 1 Peptidase MA superfamily Peptidase_M61 PF05299.12 KXG54722.1 - 0.096 13.1 2.6 2.6 8.5 1.8 3.1 2 1 0 2 2 2 0 M61 glycyl aminopeptidase MIT PF04212.18 KXG54723.1 - 2.6e-12 46.6 0.5 7.3e-12 45.2 0.5 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DEAD_assoc PF08494.11 KXG54723.1 - 0.24 11.2 2.8 2 8.2 0.0 2.4 2 0 0 2 2 2 0 DEAD/H associated REV PF00424.18 KXG54723.1 - 4.9 7.2 6.6 6.3 6.9 0.0 3.2 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) Peptidase_M24 PF00557.24 KXG54726.1 - 4.3e-54 183.4 0.3 5.9e-54 182.9 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXG54726.1 - 4.7e-26 90.9 0.0 1.2e-25 89.6 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain BTB PF00651.31 KXG54727.1 - 0.0024 18.1 0.0 0.0076 16.5 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain DLH PF01738.18 KXG54729.1 - 5.2e-26 91.5 0.0 6e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KXG54729.1 - 0.0027 18.3 0.2 0.0033 18.1 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family CH PF00307.31 KXG54730.1 - 4.1e-74 245.8 0.0 7.6e-21 74.3 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KXG54730.1 - 5e-06 26.9 0.7 0.00018 21.9 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain pair CAMSAP_CH PF11971.8 KXG54730.1 - 0.00039 20.2 0.0 0.16 11.9 0.0 3.5 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_6 PF13405.6 KXG54730.1 - 0.014 15.2 0.2 3.3 7.9 0.0 3.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 KXG54730.1 - 0.11 12.1 0.3 11 5.8 0.1 3.3 3 0 0 3 3 3 0 EF hand DDHD PF02862.17 KXG54731.1 - 2.8e-43 148.7 0.0 9.4e-43 146.9 0.0 1.9 2 0 0 2 2 2 1 DDHD domain RNase_3_N PF18497.1 KXG54731.1 - 0.011 16.0 0.0 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease III N-terminal domain PXA PF02194.15 KXG54732.1 - 1.7e-32 112.9 0.2 3.3e-32 111.9 0.2 1.5 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KXG54732.1 - 1.2e-22 80.6 0.0 4.1e-22 78.9 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PC4 PF02229.16 KXG54732.1 - 6.7e-22 76.9 0.1 1.5e-21 75.8 0.1 1.6 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) PX PF00787.24 KXG54732.1 - 2.4e-09 37.2 0.3 1e-08 35.2 0.0 2.2 2 0 0 2 2 2 1 PX domain TPR_14 PF13428.6 KXG54732.1 - 0.088 13.7 0.1 0.31 12.0 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Hydantoinase_B PF02538.14 KXG54733.1 - 3.6e-224 745.0 0.0 4.7e-224 744.6 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXG54733.1 - 4.7e-101 337.9 0.2 6.8e-101 337.4 0.2 1.2 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXG54733.1 - 9.2e-57 191.6 0.4 3.7e-55 186.4 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region RRM_1 PF00076.22 KXG54733.1 - 9.9e-11 41.3 0.0 2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXG54733.1 - 0.0064 16.5 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ribosomal_L18 PF17135.4 KXG54734.1 - 1.3e-84 282.3 7.0 1.4e-83 278.9 7.0 2.0 1 1 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Mito_carr PF00153.27 KXG54734.1 - 1.9e-69 229.6 1.9 9.2e-23 80.0 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXG54734.1 - 0.00049 19.3 2.0 0.0053 16.0 0.0 3.1 3 1 2 5 5 5 1 Gammaproteobacterial serine protease Ribosomal_L27A PF00828.19 KXG54734.1 - 0.0039 17.9 0.1 0.009 16.7 0.1 1.7 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Aldedh PF00171.22 KXG54735.1 - 8.6e-13 47.6 8.1 1.7e-11 43.4 5.1 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXG54735.1 - 0.015 14.7 0.4 0.034 13.6 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1487) DUF2209 PF09974.9 KXG54735.1 - 0.13 12.6 0.3 0.35 11.2 0.3 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) PP-binding PF00550.25 KXG54736.1 - 4.8e-14 52.5 0.0 1.5e-13 50.8 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 KXG54736.1 - 1.2e-11 44.0 0.0 2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Methyltransf_23 PF13489.6 KXG54736.1 - 5.2e-05 23.1 0.0 0.00022 21.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXG54736.1 - 9.1e-05 23.1 0.0 0.00044 20.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain AMP-binding_C PF13193.6 KXG54736.1 - 0.00064 20.6 0.0 0.003 18.5 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Methyltransf_11 PF08241.12 KXG54736.1 - 0.0043 17.7 0.0 0.013 16.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXG54736.1 - 0.014 16.1 0.0 0.055 14.2 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.28 KXG54739.1 - 2.1e-70 237.5 0.0 2.9e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KXG54739.1 - 1.5e-41 142.6 0.0 2.2e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Condensation domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Penicillium_griseofulvum-ASM156193v1/GCA_001561935.1_ASM156193v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Penicillium_griseofulvum-ASM156193v1/GCA_001561935.1_ASM156193v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Penicillium_griseofulvum-ASM156193v1/GCA_001561935.1_ASM156193v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Penicillium_griseofulvum-ASM156193v1/GCA_001561935.1_ASM156193v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 02:32:40 2019 # [ok]