# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Abhydrolase_2 PF02230.16 KUM55324.1 - 1.2e-12 48.2 0.0 1.4e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KUM55324.1 - 0.0021 18.7 0.5 0.0027 18.4 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Condensation PF00668.20 KUM55328.1 - 8.6e-49 166.4 0.1 1e-48 166.2 0.1 1.0 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KUM55328.1 - 5.8e-15 55.4 0.0 1.1e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site SepZ PF06066.11 KUM55328.1 - 0.14 12.4 0.0 0.61 10.3 0.0 2.0 2 0 0 2 2 2 0 SepZ HTH_psq PF05225.16 KUM55329.1 - 2.5e-08 33.5 0.0 3.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain CENP-B_N PF04218.13 KUM55329.1 - 9.5e-05 22.0 0.1 0.00014 21.4 0.1 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_24 PF13412.6 KUM55329.1 - 0.00057 19.4 0.3 0.00092 18.7 0.3 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 KUM55329.1 - 0.0006 19.9 0.0 0.00087 19.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KUM55329.1 - 0.0017 18.1 0.1 0.0023 17.7 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 KUM55329.1 - 0.0022 17.8 0.1 0.0029 17.5 0.1 1.2 1 0 0 1 1 1 1 MarR family UPF0175 PF03683.13 KUM55329.1 - 0.0039 16.9 0.1 0.0056 16.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0175) TrmB PF01978.19 KUM55329.1 - 0.0094 15.8 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB BrkDBD PF09607.10 KUM55329.1 - 0.01 15.6 0.1 0.013 15.2 0.1 1.2 1 0 0 1 1 1 0 Brinker DNA-binding domain HTH_7 PF02796.15 KUM55329.1 - 0.031 14.4 0.1 0.037 14.1 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_3 PF01381.22 KUM55329.1 - 0.032 14.3 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix HTH_6 PF01418.17 KUM55329.1 - 0.04 13.9 0.2 0.07 13.1 0.0 1.4 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_30 PF13556.6 KUM55329.1 - 0.05 13.4 0.1 0.085 12.7 0.1 1.5 1 1 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Rrf2 PF02082.20 KUM55329.1 - 0.05 14.0 0.0 0.061 13.7 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator FeThRed_A PF02941.15 KUM55329.1 - 0.06 13.5 0.0 0.069 13.3 0.0 1.1 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase variable alpha chain HTH_37 PF13744.6 KUM55329.1 - 0.067 13.2 0.6 0.09 12.7 0.6 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain MerR PF00376.23 KUM55329.1 - 0.067 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 MerR family regulatory protein HTH_10 PF04967.12 KUM55329.1 - 0.075 12.9 1.4 0.09 12.6 0.0 2.0 2 1 0 2 2 2 0 HTH DNA binding domain Sigma70_r4_2 PF08281.12 KUM55329.1 - 0.08 12.6 0.0 0.62 9.8 0.0 2.1 1 1 0 1 1 1 0 Sigma-70, region 4 zf-CCHC PF00098.23 KUM55330.1 - 2e-05 24.5 3.4 3.5e-05 23.7 3.4 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 KUM55330.1 - 0.00033 20.3 0.0 0.00097 18.8 0.0 1.8 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type PNMA PF14893.6 KUM55330.1 - 0.0019 17.7 1.2 0.0023 17.4 1.2 1.2 1 0 0 1 1 1 1 PNMA zf-CCHC_3 PF13917.6 KUM55330.1 - 0.0074 16.2 0.6 0.0074 16.2 0.6 2.1 2 0 0 2 2 2 1 Zinc knuckle HALZ PF02183.18 KUM55330.1 - 0.075 13.3 2.0 0.18 12.1 2.0 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 KUM55330.1 - 0.11 12.2 2.3 0.41 10.4 2.2 2.0 2 0 0 2 2 2 0 Septum formation initiator zf-CCHC_6 PF15288.6 KUM55330.1 - 0.38 10.6 3.2 0.81 9.6 3.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 KUM55330.1 - 0.54 10.0 3.8 1.2 8.9 3.8 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger HTH_psq PF05225.16 KUM55332.1 - 1.1e-08 34.7 0.1 1.6e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 KUM55332.1 - 0.0013 18.8 0.3 0.002 18.2 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 KUM55332.1 - 0.0026 17.3 1.0 0.0028 17.3 0.1 1.6 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain SpoIIID PF12116.8 KUM55332.1 - 0.032 14.3 0.1 0.034 14.2 0.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein D MarR_2 PF12802.7 KUM55332.1 - 0.033 14.1 0.4 0.055 13.4 0.4 1.4 1 0 0 1 1 1 0 MarR family pXO2-72 PF17443.2 KUM55332.1 - 0.033 14.4 0.1 0.05 13.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein pXO2-72 HTH_IclR PF09339.10 KUM55332.1 - 0.041 13.7 0.5 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_23 PF13384.6 KUM55332.1 - 0.051 13.4 0.9 0.084 12.7 0.9 1.6 1 1 0 1 1 1 0 Homeodomain-like domain MerR PF00376.23 KUM55332.1 - 0.056 13.2 0.1 0.17 11.7 0.1 1.8 1 0 0 1 1 1 0 MerR family regulatory protein HTH_17 PF12728.7 KUM55332.1 - 0.064 13.5 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Helo_like_N PF17111.5 KUM55333.1 - 4.9e-42 143.7 0.0 5.6e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins MADF_DNA_bdg PF10545.9 KUM55336.1 - 0.085 13.2 0.5 0.12 12.6 0.5 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like BIR PF00653.21 KUM55337.1 - 4.1e-05 24.1 0.1 8e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain VIT_2 PF13757.6 KUM55339.1 - 0.13 12.2 0.1 0.15 12.0 0.1 1.2 1 1 0 1 1 1 0 Vault protein inter-alpha-trypsin domain APH PF01636.23 KUM55342.1 - 1.3e-11 44.9 0.0 1.8e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KUM55342.1 - 2.7e-05 23.9 0.0 4.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KUM55342.1 - 0.00026 20.4 0.1 0.00038 19.9 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 KUM55342.1 - 0.00032 19.7 0.0 0.001 18.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Pkinase PF00069.25 KUM55342.1 - 0.0005 19.5 0.0 0.072 12.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KUM55342.1 - 0.018 14.4 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.14 KUM55342.1 - 0.03 13.5 0.1 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase Pox_ser-thr_kin PF05445.11 KUM55342.1 - 0.052 12.5 0.1 5.8 5.8 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Pkinase_Tyr PF07714.17 KUM55342.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase CDO_I PF05995.12 KUM55343.1 - 8.9e-40 135.7 0.0 1.1e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I GNVR PF13807.6 KUM55344.1 - 0.0044 16.9 0.3 1.1 9.2 0.1 2.6 1 1 1 2 2 2 2 G-rich domain on putative tyrosine kinase AFP PF02420.15 KUM55344.1 - 4.1 8.1 19.9 54 4.6 0.0 7.4 8 0 0 8 8 8 0 Insect antifreeze protein repeat DUF1822 PF08852.11 KUM55351.1 - 0.093 11.8 0.1 0.11 11.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) PP-binding PF00550.25 KUM55354.1 - 2.6e-07 30.9 0.0 8.7e-07 29.2 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 KUM55354.1 - 3.6e-05 23.7 0.0 0.00017 21.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain AMP-binding_C PF13193.6 KUM55354.1 - 9.2e-05 23.3 0.1 0.0027 18.6 0.0 3.1 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Methyltransf_25 PF13649.6 KUM55354.1 - 9.3e-05 23.1 0.0 0.00035 21.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM55354.1 - 0.0034 18.0 0.0 0.01 16.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM55354.1 - 0.011 16.5 0.0 0.044 14.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain AAA PF00004.29 KUM55356.1 - 1.1e-42 145.5 0.0 1.9e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KUM55356.1 - 4.7e-14 51.9 0.0 1.1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KUM55356.1 - 4.3e-07 30.0 0.0 1.2e-06 28.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KUM55356.1 - 4.8e-07 30.1 0.0 9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KUM55356.1 - 4e-06 27.3 0.0 0.00019 21.8 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KUM55356.1 - 7.5e-05 23.0 0.2 0.025 14.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain Prot_ATP_ID_OB PF16450.5 KUM55356.1 - 9.4e-05 22.3 2.8 0.00022 21.1 2.8 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_18 PF13238.6 KUM55356.1 - 0.00062 20.3 0.0 0.033 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KUM55356.1 - 0.00064 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KUM55356.1 - 0.0062 15.8 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KUM55356.1 - 0.0063 16.7 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KUM55356.1 - 0.0077 15.6 0.1 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 KaiC IstB_IS21 PF01695.17 KUM55356.1 - 0.0078 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KUM55356.1 - 0.014 14.8 0.1 0.033 13.6 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KUM55356.1 - 0.018 14.9 0.0 0.055 13.3 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KUM55356.1 - 0.025 14.3 0.0 0.06 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KUM55356.1 - 0.033 13.6 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 KUM55356.1 - 0.039 14.0 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KUM55356.1 - 0.048 12.8 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) HR1 PF02185.16 KUM55356.1 - 0.052 13.7 0.6 0.12 12.5 0.6 1.6 1 0 0 1 1 1 0 Hr1 repeat Sigma54_activat PF00158.26 KUM55356.1 - 0.059 13.1 0.0 0.24 11.1 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KUM55356.1 - 0.065 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KUM55356.1 - 0.067 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Prot_ATP_OB_N PF17758.1 KUM55356.1 - 0.082 12.6 0.3 0.28 10.9 0.1 2.1 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain DUF2072 PF09845.9 KUM55356.1 - 0.087 13.1 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_25 PF13481.6 KUM55356.1 - 0.09 12.3 0.1 0.24 11.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 KUM55356.1 - 0.092 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KUM55356.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KUM55356.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TPR_12 PF13424.6 KUM55358.1 - 8.7e-100 327.1 33.5 5.1e-22 78.0 1.4 5.5 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 KUM55358.1 - 2.1e-75 246.7 23.3 2e-14 52.9 0.1 7.4 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 KUM55358.1 - 2.2e-32 108.7 12.7 5.6e-07 29.2 0.1 6.4 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 KUM55358.1 - 3.7e-32 108.8 0.3 8.5e-05 22.2 0.0 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 KUM55358.1 - 3.1e-21 73.7 1.4 0.0065 16.6 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 KUM55358.1 - 1.8e-14 54.1 4.9 0.0016 19.0 0.2 5.8 3 3 3 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 KUM55358.1 - 3.1e-14 52.2 0.3 0.27 11.7 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KUM55358.1 - 1.9e-13 50.0 7.4 0.029 15.2 0.2 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KUM55358.1 - 1.5e-12 46.6 7.9 0.29 11.4 0.1 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat NRBF2_MIT PF17169.4 KUM55358.1 - 3e-09 37.0 3.7 3.3 8.0 0.0 6.0 5 1 1 6 6 6 2 MIT domain of nuclear receptor-binding factor 2 DUF1925 PF09094.11 KUM55358.1 - 7.5e-09 35.8 5.9 1.4 9.3 0.0 5.6 2 2 2 5 5 5 3 Domain of unknown function (DUF1925) TPR_19 PF14559.6 KUM55358.1 - 2e-08 34.6 2.0 0.028 14.9 0.3 3.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.14 KUM55358.1 - 3.6e-08 33.3 0.5 14 6.6 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KUM55358.1 - 1.4e-07 31.2 3.1 8.2e-05 22.1 0.5 2.1 1 1 1 2 2 2 2 MalT-like TPR region ANAPC3 PF12895.7 KUM55358.1 - 4.2e-07 30.1 0.1 0.39 11.0 0.2 4.8 1 1 5 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KUM55358.1 - 5.4e-07 29.6 0.4 2.2 8.4 0.0 4.4 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain PPR PF01535.20 KUM55358.1 - 1.6e-06 27.9 1.2 0.13 12.6 0.0 5.2 5 0 0 5 5 5 1 PPR repeat TPR_11 PF13414.6 KUM55358.1 - 0.00012 21.6 2.9 48 3.7 0.0 5.5 5 0 0 5 5 5 0 TPR repeat TPR_5 PF12688.7 KUM55358.1 - 0.00015 22.0 5.1 0.0028 17.9 0.6 3.5 2 1 0 3 3 3 1 Tetratrico peptide repeat nec1 PF10379.9 KUM55358.1 - 0.00017 21.2 0.0 3.7 7.0 0.0 4.1 1 1 4 5 5 5 1 Virulence protein nec1 PAS_4 PF08448.10 KUM55358.1 - 0.0033 17.6 1.7 2.3 8.5 0.1 3.5 1 1 4 5 5 5 2 PAS fold TPR_3 PF07720.12 KUM55358.1 - 0.0055 16.7 0.2 94 3.2 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF627 PF04781.12 KUM55358.1 - 0.039 14.0 1.2 26 4.9 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF627) Coatomer_E PF04733.14 KUM55358.1 - 0.04 13.3 3.3 13 5.1 0.1 3.3 1 1 3 4 4 4 0 Coatomer epsilon subunit Atu4866 PF11512.8 KUM55358.1 - 0.089 13.2 5.6 15 6.1 0.2 4.1 4 1 0 4 4 4 0 Agrobacterium tumefaciens protein Atu4866 ISG65-75 PF11727.8 KUM55358.1 - 0.27 10.4 3.8 7 5.8 0.1 3.4 2 2 3 5 5 5 0 Invariant surface glycoprotein DUF1897 PF09005.10 KUM55358.1 - 0.38 10.3 13.1 44 3.7 0.0 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF1897) Mad3_BUB1_I PF08311.12 KUM55358.1 - 0.51 10.3 1.6 1.2e+02 2.7 0.0 3.5 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 rve PF00665.26 KUM55359.1 - 3.8e-10 40.0 0.0 4.5e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Thiolase_N PF00108.23 KUM55360.1 - 2.6e-58 197.5 0.0 2.9e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 KUM55360.1 - 0.0014 18.3 0.3 0.0032 17.1 0.1 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain RNase_H PF00075.24 KUM55361.1 - 5.2e-10 39.7 0.0 7.1e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KUM55361.1 - 0.1 12.4 0.0 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase-like 7TM_GPCR_Sri PF10327.9 KUM55363.1 - 0.039 13.1 0.1 0.05 12.8 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Pkinase PF00069.25 KUM55368.1 - 1.5e-25 90.1 0.0 6e-25 88.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM55368.1 - 8.4e-05 22.0 0.5 0.039 13.2 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 KUM55368.1 - 0.073 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 RIO1 family DUF5053 PF16476.5 KUM55368.1 - 0.12 12.1 0.0 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) Coatomer_E PF04733.14 KUM55369.1 - 5e-58 196.8 3.5 5.7e-58 196.6 3.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KUM55369.1 - 6.9e-12 45.7 16.6 0.0072 16.8 4.2 4.5 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KUM55369.1 - 1.3e-07 31.8 15.9 0.013 16.3 0.1 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KUM55369.1 - 3.3e-07 30.8 14.0 0.0082 16.8 2.8 4.1 3 1 2 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM55369.1 - 5.2e-07 29.8 1.5 0.0027 17.9 0.7 3.7 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KUM55369.1 - 7.9e-06 25.6 9.6 0.022 14.8 0.0 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KUM55369.1 - 1.2e-05 25.7 5.7 0.017 15.7 0.2 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 KUM55369.1 - 4e-05 23.8 17.3 0.42 11.4 0.3 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KUM55369.1 - 0.003 17.8 11.4 1.8 8.9 3.7 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KUM55369.1 - 0.003 17.7 5.4 1.3 9.2 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KUM55369.1 - 0.014 15.2 4.5 1 9.3 0.0 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KUM55369.1 - 0.19 11.6 3.4 0.41 10.5 0.7 2.4 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TPR_20 PF14561.6 KUM55369.1 - 0.36 11.2 11.7 1.2 9.5 1.3 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.13 KUM55370.1 - 1.7e-09 37.8 0.0 2e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KUM55370.1 - 5.1e-07 28.9 0.0 6.1e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S10 PF00450.22 KUM55372.1 - 4.6e-109 365.6 1.1 5.4e-109 365.4 1.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase RT_RNaseH PF17917.1 KUM55373.1 - 1.1e-32 112.4 0.1 2.3e-32 111.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KUM55373.1 - 2e-31 108.0 0.0 5.8e-31 106.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KUM55373.1 - 8.4e-17 61.5 0.1 2e-16 60.3 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KUM55373.1 - 3e-16 59.3 0.5 7.7e-16 57.9 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KUM55373.1 - 2.8e-05 24.2 0.4 6.2e-05 23.1 0.4 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 KUM55373.1 - 3.8e-05 23.5 0.4 9.7e-05 22.2 0.4 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain G-7-MTase PF12803.7 KUM55373.1 - 0.025 13.8 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) CSN7a_helixI PF18392.1 KUM55373.1 - 0.15 12.0 1.0 2.2 8.3 0.2 3.0 3 0 0 3 3 3 0 COP9 signalosome complex subunit 7a helix I domain Metallophos PF00149.28 KUM55378.1 - 5.4e-37 128.3 0.1 8.6e-37 127.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KUM55378.1 - 3.7e-18 65.7 0.0 6.2e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Lys PF00062.20 KUM55380.1 - 0.029 14.6 0.0 0.043 14.1 0.0 1.3 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family gag-asp_proteas PF13975.6 KUM55389.1 - 0.012 16.2 0.0 0.057 14.0 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease MmlI PF09448.10 KUM55389.1 - 0.033 14.7 0.1 0.13 12.7 0.0 2.1 2 1 0 2 2 2 0 Methylmuconolactone methyl-isomerase RVP_2 PF08284.11 KUM55389.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF2267 PF10025.9 KUM55389.1 - 0.12 12.6 0.0 0.28 11.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) Med4 PF10018.9 KUM55390.1 - 8.9e-51 172.3 0.3 1.5e-50 171.6 0.3 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 HsbA PF12296.8 KUM55390.1 - 0.022 15.2 0.8 0.022 15.2 0.8 1.8 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Rac1 PF09632.10 KUM55390.1 - 0.11 11.7 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Rac1-binding domain TBCA PF02970.16 KUM55390.1 - 0.18 12.1 1.9 0.32 11.4 0.1 2.2 2 1 1 3 3 3 0 Tubulin binding cofactor A YL1 PF05764.13 KUM55390.1 - 0.36 10.9 4.4 0.066 13.3 0.9 1.6 2 0 0 2 2 2 0 YL1 nuclear protein Ank_2 PF12796.7 KUM55392.1 - 8e-52 173.8 0.7 1.4e-17 64.0 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM55392.1 - 3.1e-37 126.5 0.0 8.4e-12 45.4 0.0 6.0 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KUM55392.1 - 4e-29 99.7 0.1 0.00065 20.0 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KUM55392.1 - 4.1e-29 97.4 0.2 0.0062 16.9 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KUM55392.1 - 4.1e-15 55.7 2.1 1.4e-06 28.5 0.0 4.9 1 1 6 7 7 7 4 Ankyrin repeats (many copies) F-box-like PF12937.7 KUM55392.1 - 1.3e-06 28.2 0.3 2.9e-06 27.1 0.3 1.6 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 KUM55400.1 - 2.9e-36 125.1 24.8 2.4e-35 122.1 25.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KUM55400.1 - 0.002 17.5 1.0 0.002 17.5 1.0 2.5 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB PspB PF06667.12 KUM55400.1 - 0.11 12.6 0.1 0.41 10.7 0.1 2.0 1 0 0 1 1 1 0 Phage shock protein B Acetyltransf_1 PF00583.25 KUM55401.1 - 9.3e-20 71.0 0.0 1.2e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KUM55401.1 - 1.3e-09 38.3 0.0 1.9e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KUM55401.1 - 3.1e-09 36.9 0.0 3.5e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KUM55401.1 - 1.3e-06 28.3 0.0 1.8e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KUM55401.1 - 0.00012 22.8 0.1 0.00014 22.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KUM55401.1 - 0.0052 16.9 0.0 0.0062 16.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KUM55401.1 - 0.0085 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase RdDM_RDM1 PF09187.10 KUM55402.1 - 0.088 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA-directed DNA methylation 1 Cyt-b5 PF00173.28 KUM55405.1 - 9.8e-08 32.0 0.0 1.2e-07 31.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.22 KUM55406.1 - 9.2e-58 192.0 0.1 2.1e-19 69.1 0.1 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KUM55406.1 - 1.1e-06 29.0 3.4 0.7 10.1 0.0 6.1 4 3 1 5 5 5 2 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 KUM55406.1 - 0.00099 18.7 0.0 0.25 10.9 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KUM55406.1 - 0.0025 17.7 0.1 2.1 8.1 0.0 3.2 2 1 1 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 KUM55406.1 - 0.0046 16.8 0.1 1.1 9.2 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif SET_assoc PF11767.8 KUM55406.1 - 0.033 13.8 0.1 26 4.5 0.0 3.5 3 1 0 3 3 3 0 Histone lysine methyltransferase SET associated FAD_binding_4 PF01565.23 KUM55407.1 - 5.7e-13 48.8 1.8 2e-12 47.0 1.8 2.0 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KUM55407.1 - 3.1e-10 40.0 1.1 6.9e-10 38.9 1.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KUM55407.1 - 0.0023 17.4 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding AAA_12 PF13087.6 KUM55408.1 - 7.1e-17 61.7 0.0 8.4e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KUM55408.1 - 8.2e-06 25.6 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KUM55408.1 - 0.0013 18.5 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KUM55409.1 - 1e-08 35.3 0.0 1.5e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KUM55409.1 - 0.016 15.5 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KUM55409.1 - 0.096 12.4 0.0 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain Glyco_transf_90 PF05686.12 KUM55412.1 - 4e-17 62.2 3.6 1.6e-15 56.9 1.1 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 Methyltransf_23 PF13489.6 KUM55417.1 - 5.7e-22 78.3 0.0 8.6e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM55417.1 - 1.2e-10 41.4 0.0 1.2e-09 38.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM55417.1 - 2.2e-07 31.5 0.0 5.8e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM55417.1 - 4.1e-05 24.2 0.0 0.00084 20.0 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KUM55417.1 - 0.0019 17.7 0.0 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KUM55417.1 - 0.0039 16.8 0.0 0.0075 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KUM55417.1 - 0.0052 17.4 0.0 0.01 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KUM55417.1 - 0.015 15.4 0.0 0.038 14.1 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KUM55417.1 - 0.025 14.3 0.0 0.074 12.8 0.0 1.7 2 0 0 2 2 2 0 Lysine methyltransferase PrmA PF06325.13 KUM55417.1 - 0.082 12.3 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Transposase_28 PF04195.12 KUM55417.1 - 0.15 12.3 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 Putative gypsy type transposon PCMT PF01135.19 KUM55417.1 - 0.23 11.2 0.0 0.68 9.6 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPR_10 PF13374.6 KUM55419.1 - 2.9e-113 367.1 0.0 3.2e-14 52.3 0.0 10.1 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_12 PF13424.6 KUM55419.1 - 2.2e-94 309.9 16.8 3.9e-18 65.5 0.1 8.3 3 2 4 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.6 KUM55419.1 - 8e-47 153.9 8.9 0.00018 21.3 0.0 10.2 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_1 PF00515.28 KUM55419.1 - 4.6e-30 102.2 5.6 0.0052 16.6 0.0 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 KUM55419.1 - 1.1e-29 100.1 6.0 0.017 15.2 0.0 10.0 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 KUM55419.1 - 8.3e-25 84.9 14.2 0.19 12.0 0.0 10.2 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_4 PF07721.14 KUM55419.1 - 4.5e-23 79.4 12.6 0.015 15.8 0.3 9.2 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 KUM55419.1 - 4.6e-23 81.5 2.2 0.013 16.0 0.1 9.6 6 3 4 10 10 10 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KUM55419.1 - 1.6e-22 80.4 9.3 3.4e-10 39.8 4.9 3.2 2 1 1 3 3 3 3 MalT-like TPR region TPR_16 PF13432.6 KUM55419.1 - 1.7e-19 70.2 0.2 0.044 14.4 0.2 8.7 6 1 3 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 KUM55419.1 - 5.4e-19 67.1 10.4 0.29 11.6 0.1 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 KUM55419.1 - 6e-13 48.4 13.0 0.28 12.1 0.0 9.5 9 1 1 10 10 10 2 Tetratricopeptide repeat PPR PF01535.20 KUM55419.1 - 1.5e-12 46.8 0.3 0.36 11.2 0.0 7.9 8 0 0 8 8 8 1 PPR repeat ANAPC3 PF12895.7 KUM55419.1 - 5.6e-09 36.1 0.5 0.88 9.8 0.0 6.7 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KUM55419.1 - 1.4e-08 34.9 3.3 1.7 9.0 0.0 7.5 3 2 3 8 8 8 1 Tetratricopeptide repeat RPN6_N PF18055.1 KUM55419.1 - 2.7e-06 27.7 9.4 5.4 7.4 0.1 6.0 2 2 6 8 8 8 2 26S proteasome regulatory subunit RPN6 N-terminal domain SNAP PF14938.6 KUM55419.1 - 9.8e-05 21.9 0.2 0.22 10.9 0.0 4.1 1 1 2 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 KUM55419.1 - 0.0014 19.1 16.7 19 6.2 0.0 8.3 9 0 0 9 9 9 0 Tetratricopeptide repeat SLT_2 PF13406.6 KUM55419.1 - 0.002 17.4 0.7 0.26 10.5 0.0 3.4 1 1 1 3 3 3 1 Transglycosylase SLT domain PPR_2 PF13041.6 KUM55419.1 - 0.0023 18.1 3.3 63 3.9 0.0 6.9 8 0 0 8 8 8 0 PPR repeat family DUF4919 PF16266.5 KUM55419.1 - 0.0057 16.6 0.1 9 6.2 0.0 4.1 3 1 2 5 5 5 0 Domain of unknown function (DUF4919) DUF4747 PF15931.5 KUM55419.1 - 0.036 13.7 0.1 10 5.7 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4747) YfdX PF10938.8 KUM55419.1 - 0.053 13.5 0.5 2 8.3 0.1 2.6 3 0 0 3 3 2 0 YfdX protein GLTP PF08718.11 KUM55419.1 - 0.077 13.3 0.1 3.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) Cytochrom_B562 PF07361.11 KUM55419.1 - 0.094 13.4 1.9 36 5.1 0.1 3.7 4 0 0 4 4 3 0 Cytochrome b562 TPR_11 PF13414.6 KUM55419.1 - 0.27 10.9 15.1 9.4 6.0 0.0 6.9 8 0 0 8 8 7 0 TPR repeat HrpB1_HrpK PF09613.10 KUM55419.1 - 0.33 10.6 2.9 5.2 6.7 0.2 3.9 4 1 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF4363 PF14276.6 KUM55419.1 - 0.66 10.1 3.1 35 4.6 0.1 4.4 6 0 0 6 6 4 0 Domain of unknown function (DUF4363) Myb_DNA-bind_6 PF13921.6 KUM55422.1 - 0.001 19.3 0.2 0.0021 18.3 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KUM55422.1 - 0.0054 16.9 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Nab1 PF04902.12 KUM55422.1 - 0.036 14.5 0.0 6.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Conserved region in Nab1 EcKinase PF02958.20 KUM55423.1 - 3.8e-08 33.0 0.1 7.3e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 KUM55423.1 - 1.4e-07 31.7 0.0 2.3e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KUM55423.1 - 6.2e-05 22.7 0.0 9.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KUM55423.1 - 0.049 12.8 0.0 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Fructosamine kinase DUF1679 PF07914.11 KUM55423.1 - 0.069 12.0 0.0 0.097 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Aegerolysin PF06355.13 KUM55424.1 - 3e-38 130.8 0.3 3.6e-38 130.6 0.3 1.0 1 0 0 1 1 1 1 Aegerolysin RVT_1 PF00078.27 KUM55425.1 - 6.7e-18 65.0 0.0 6e-11 42.3 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_32N PF00251.20 KUM55426.1 - 2e-88 296.9 4.5 9.1e-71 238.9 0.4 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KUM55426.1 - 3.3e-33 114.9 0.3 5.9e-33 114.1 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal CHB_HEX_C PF03174.13 KUM55426.1 - 0.084 12.9 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain BNR PF02012.20 KUM55426.1 - 3 8.2 5.5 3.7 7.9 0.1 3.9 3 0 0 3 3 3 0 BNR/Asp-box repeat MFS_1 PF07690.16 KUM55429.1 - 6.1e-33 114.2 54.3 6.1e-33 114.2 54.3 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM55429.1 - 7.1e-22 77.6 20.7 7.1e-22 77.6 20.7 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM55429.1 - 9.3e-12 44.5 5.5 9.3e-12 44.5 5.5 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KUM55429.1 - 3.1 6.0 14.8 0.1 10.9 5.2 2.7 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Elf1 PF05129.13 KUM55430.1 - 0.93 9.6 7.6 2.2 8.4 7.6 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-CCHC PF00098.23 KUM55430.1 - 1.1 9.4 6.9 1.8 8.8 0.9 2.7 2 0 0 2 2 2 0 Zinc knuckle DNA_RNApol_7kD PF03604.13 KUM55430.1 - 4.1 7.2 6.4 60 3.4 6.4 2.5 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit PolC_DP2 PF03833.13 KUM55430.1 - 5.8 4.7 7.9 8 4.2 7.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-CCHC_5 PF14787.6 KUM55430.1 - 8.5 6.2 11.6 0.087 12.5 3.0 2.1 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger Exo_endo_phos_2 PF14529.6 KUM55431.1 - 3.6e-21 75.2 0.6 1.9e-20 72.9 0.1 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KUM55431.1 - 0.00026 20.6 0.1 0.00096 18.7 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cupin_2 PF07883.11 KUM55432.1 - 4.3e-07 29.5 0.0 8.5e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KUM55432.1 - 0.025 14.2 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) ADH_zinc_N PF00107.26 KUM55433.1 - 6.6e-27 94.1 0.1 1e-26 93.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM55433.1 - 1.1e-22 81.5 0.0 2.4e-22 80.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM55433.1 - 2.2e-09 37.2 0.6 4.5e-09 36.2 0.1 1.8 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KUM55433.1 - 0.069 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3716 PF12511.8 KUM55435.1 - 7.2e-09 35.6 0.1 1.1e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF4404 PF14357.6 KUM55435.1 - 0.11 13.1 1.7 0.18 12.5 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Myb_DNA-bind_6 PF13921.6 KUM55437.1 - 0.063 13.5 0.7 0.063 13.5 0.7 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain APH PF01636.23 KUM55440.1 - 3.6e-16 59.8 0.0 1.4e-15 57.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KUM55440.1 - 1.3e-06 28.1 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KUM55440.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.22 KUM55440.1 - 0.03 13.9 0.0 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 RIO1 family DUF3435 PF11917.8 KUM55441.1 - 1.2e-20 73.9 0.3 1.6e-20 73.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) p450 PF00067.22 KUM55442.1 - 2e-34 119.2 0.0 7.9e-34 117.2 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 FSAP_sig_propep PF03032.15 KUM55444.1 - 0.066 13.2 1.8 0.12 12.4 1.8 1.4 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide UQ_con PF00179.26 KUM55446.1 - 1.6e-47 160.6 0.0 2e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KUM55446.1 - 0.00033 20.9 0.0 0.00044 20.5 0.0 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KUM55446.1 - 0.00039 20.1 0.0 0.00059 19.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KUM55446.1 - 0.00089 19.1 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 UEV domain RNase_H PF00075.24 KUM55447.1 - 1.7e-07 31.5 0.1 4.3e-07 30.2 0.1 1.7 1 1 0 1 1 1 1 RNase H Glyco_hydro_18 PF00704.28 KUM55448.1 - 3.5e-24 86.1 0.1 1.1e-23 84.5 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 GWT1 PF06423.12 KUM55450.1 - 2.2 8.4 7.7 1.7 8.7 6.2 1.7 1 1 0 1 1 1 0 GWT1 DUF3669 PF12417.8 KUM55451.1 - 7.4e-15 54.9 0.1 3e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 Zinc finger protein HALZ PF02183.18 KUM55452.1 - 0.00082 19.6 1.8 0.0015 18.7 1.8 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper DivIC PF04977.15 KUM55452.1 - 0.01 15.6 1.2 0.016 15.0 1.2 1.3 1 0 0 1 1 1 0 Septum formation initiator APG6_N PF17675.1 KUM55452.1 - 0.016 15.7 1.9 0.02 15.5 1.9 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region bZIP_1 PF00170.21 KUM55452.1 - 0.028 14.5 2.9 0.046 13.8 2.9 1.4 1 1 0 1 1 1 0 bZIP transcription factor TSC22 PF01166.18 KUM55452.1 - 0.03 14.6 0.3 0.052 13.9 0.3 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family FapA PF03961.13 KUM55452.1 - 0.051 12.2 0.9 0.057 12.0 0.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3360 PF11840.8 KUM55452.1 - 0.51 9.0 0.7 0.63 8.7 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) adh_short PF00106.25 KUM55453.1 - 4.1e-14 52.5 1.0 4.6e-14 52.3 1.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM55453.1 - 1.1e-11 44.8 0.5 1.2e-11 44.6 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM55453.1 - 2.9e-07 30.6 0.1 3.2e-07 30.4 0.1 1.0 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KUM55453.1 - 0.0029 17.0 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KUM55453.1 - 0.0055 16.0 0.0 0.0057 15.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KUM55453.1 - 0.014 15.3 0.3 0.016 15.1 0.3 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KUM55453.1 - 0.049 14.1 0.1 0.062 13.7 0.1 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding FGGY_C PF02782.16 KUM55454.1 - 1.6e-47 161.8 0.7 2.2e-47 161.4 0.7 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KUM55454.1 - 3.3e-21 76.0 0.1 6.5e-20 71.7 0.1 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KUM55454.1 - 0.00036 20.1 0.1 0.0028 17.2 0.0 2.3 2 1 1 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family DEDD_Tnp_IS110 PF01548.17 KUM55454.1 - 0.085 12.7 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Transposase DUF2764 PF10962.8 KUM55454.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) RVT_1 PF00078.27 KUM55456.1 - 9.4e-34 116.9 0.0 1.4e-33 116.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KUM55456.1 - 2.7e-18 65.9 0.0 5e-17 61.8 0.0 2.8 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 KUM55456.1 - 2.8e-10 40.6 0.2 1.7e-09 38.0 0.2 2.1 1 1 0 1 1 1 1 RNase H Exo_endo_phos PF03372.23 KUM55456.1 - 1.4e-06 28.0 0.1 2.7e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Toprim_4 PF13662.6 KUM55456.1 - 0.14 12.6 0.0 0.43 11.1 0.0 1.8 1 0 0 1 1 1 0 Toprim domain C2 PF00168.30 KUM55460.1 - 4.2e-11 43.0 0.0 8.4e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain Ribosomal_L11_N PF03946.14 KUM55461.1 - 0.13 12.1 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain Fungal_trans PF04082.18 KUM55462.1 - 4.7e-11 42.2 0.2 7.8e-11 41.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM55462.1 - 2.7e-07 30.6 13.3 4.9e-07 29.8 13.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KUM55463.1 - 2e-38 132.2 56.5 2e-38 132.2 56.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM55463.1 - 4.6e-11 41.8 27.9 4.7e-11 41.8 26.9 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3188 PF11384.8 KUM55463.1 - 1.8 8.3 6.8 0.45 10.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) Fungal_trans_2 PF11951.8 KUM55464.1 - 2.1e-63 214.5 0.4 2.9e-63 214.0 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM55464.1 - 2.1e-09 37.3 11.1 3.2e-09 36.8 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2385 PF09539.10 KUM55464.1 - 0.057 13.9 0.0 23 5.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) AT_hook PF02178.19 KUM55464.1 - 0.45 10.6 6.8 1.1 9.3 6.8 1.8 1 0 0 1 1 1 0 AT hook motif Form_Nir_trans PF01226.17 KUM55465.1 - 6.3e-10 38.8 0.1 8.5e-10 38.4 0.1 1.2 1 0 0 1 1 1 1 Formate/nitrite transporter TauD PF02668.16 KUM55466.1 - 2.3e-28 99.7 0.9 6.3e-28 98.3 0.1 1.8 1 1 1 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family TSSC4 PF15264.6 KUM55466.1 - 0.034 14.4 0.1 0.059 13.6 0.1 1.3 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 2OG-Fe_Oxy_2 PF10014.9 KUM55466.1 - 0.096 12.5 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 2OG-Fe dioxygenase LssY_C PF14067.6 KUM55466.1 - 0.17 11.4 0.0 10 5.6 0.0 2.2 2 0 0 2 2 2 0 LssY C-terminus Fungal_trans PF04082.18 KUM55467.1 - 3.1e-12 46.1 0.3 1.1e-11 44.3 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KUM55467.1 - 7.4e-07 29.3 11.0 0.0067 16.8 3.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM55467.1 - 0.00037 21.1 11.0 0.069 14.0 2.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KUM55467.1 - 0.024 15.1 2.9 0.024 15.1 2.9 2.8 3 0 0 3 3 3 0 Zinc-finger double domain HWE_HK PF07536.14 KUM55467.1 - 0.18 12.5 0.7 0.44 11.3 0.7 1.7 1 0 0 1 1 1 0 HWE histidine kinase zf-UBR PF02207.20 KUM55467.1 - 0.24 11.6 1.7 0.53 10.5 1.7 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Sde2_N_Ubi PF13019.6 KUM55468.1 - 2.2e-68 229.3 0.9 3.7e-68 228.5 0.9 1.4 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain LacI PF00356.21 KUM55468.1 - 0.041 13.7 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family MMR_HSR1 PF01926.23 KUM55469.1 - 6.7e-06 26.2 0.0 0.022 14.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KUM55469.1 - 0.0054 16.6 0.0 0.013 15.4 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase ATPase-cat_bd PF12156.8 KUM55469.1 - 0.015 16.0 0.3 0.031 15.0 0.3 1.5 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Dynamin_N PF00350.23 KUM55469.1 - 0.089 12.8 0.3 0.87 9.6 0.0 2.5 3 0 0 3 3 3 0 Dynamin family Amidohydro_1 PF01979.20 KUM55470.1 - 4.1e-24 85.5 0.6 1.3e-12 47.7 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KUM55470.1 - 1.9e-12 47.4 0.2 1.6e-06 27.9 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Tox-REase-2 PF15646.6 KUM55470.1 - 0.057 13.6 0.5 0.12 12.6 0.5 1.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 2 HTH_AsnC-type PF13404.6 KUM55470.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Fungal_trans PF04082.18 KUM55471.1 - 0.0035 16.4 1.7 0.0043 16.1 0.1 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain DUF5407 PF17401.2 KUM55471.1 - 0.095 13.0 1.0 0.42 10.9 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5407) HNH_2 PF13391.6 KUM55472.1 - 1.8e-09 37.6 0.1 6.5e-09 35.8 0.1 2.0 1 1 0 1 1 1 1 HNH endonuclease ANAPC4_WD40 PF12894.7 KUM55473.1 - 5.4e-06 26.6 0.3 2.4 8.5 0.2 4.5 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KUM55473.1 - 0.0054 17.5 4.9 0.45 11.5 0.0 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat Thymidylat_synt PF00303.19 KUM55473.1 - 0.26 10.4 0.5 0.34 10.0 0.5 1.4 1 1 0 1 1 1 0 Thymidylate synthase EAR PF07897.11 KUM55473.1 - 0.42 10.3 1.7 0.51 10.0 0.4 1.9 2 0 0 2 2 2 0 Ethylene-responsive binding factor-associated repression Vps62 PF06101.11 KUM55474.1 - 1.5e-11 43.3 1.1 1.5e-11 43.3 1.1 2.3 3 0 0 3 3 3 1 Vacuolar protein sorting-associated protein 62 DUF1302 PF06980.11 KUM55474.1 - 0.41 9.2 2.5 0.76 8.3 2.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1302) ParE_toxin PF05016.15 KUM55478.1 - 0.098 13.3 0.0 0.27 11.9 0.0 1.6 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE p450 PF00067.22 KUM55480.1 - 2.3e-69 234.4 0.0 2.9e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CS PF04969.16 KUM55482.1 - 1.2e-17 64.6 0.0 2.1e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 CS domain HALZ PF02183.18 KUM55483.1 - 0.017 15.4 1.8 0.029 14.6 1.8 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 KUM55483.1 - 0.29 10.9 2.9 0.39 10.5 2.9 1.4 1 1 0 1 1 1 0 Septum formation initiator DUF3701 PF12482.8 KUM55484.1 - 0.015 15.3 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Phage integrase protein PS_Dcarbxylase PF02666.15 KUM55485.1 - 5.9e-18 65.1 0.0 6.7e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase GMC_oxred_C PF05199.13 KUM55486.1 - 5.7e-21 75.5 0.1 6.3e-21 75.4 0.1 1.0 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KUM55487.1 - 6.2e-34 117.7 0.0 7.1e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KUM55487.1 - 0.00045 19.5 0.1 0.00077 18.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KUM55487.1 - 0.0041 17.3 0.0 0.0084 16.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KUM55487.1 - 0.009 15.1 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KUM55487.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM55487.1 - 0.038 13.1 1.6 0.061 12.4 0.8 1.6 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 KUM55487.1 - 0.12 11.9 1.4 0.21 11.1 1.3 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KUM55487.1 - 0.12 12.6 0.2 0.29 11.4 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.14 KUM55487.1 - 0.14 11.0 0.1 0.2 10.5 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GMC_oxred_C PF05199.13 KUM55488.1 - 1.8e-07 31.8 0.0 2.6e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KUM55488.1 - 3.9e-06 26.5 0.7 4.9e-06 26.1 0.7 1.1 1 0 0 1 1 1 1 GMC oxidoreductase FAM176 PF14851.6 KUM55489.1 - 0.12 12.0 0.7 0.17 11.5 0.7 1.2 1 0 0 1 1 1 0 FAM176 family Epimerase PF01370.21 KUM55496.1 - 1.1e-08 34.9 0.0 0.0038 16.7 0.0 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KUM55496.1 - 8.1e-06 25.6 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM55496.1 - 3.2e-05 23.9 0.0 4.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KUM55496.1 - 0.013 14.9 0.0 0.91 8.9 0.0 2.4 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KUM55496.1 - 0.015 14.3 0.0 2.2 7.2 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KUM55496.1 - 0.065 13.7 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KUM55497.1 - 1.4e-23 83.3 1.1 2.3e-23 82.6 1.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM55497.1 - 3.1e-15 57.4 0.1 5.9e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM55497.1 - 4.4e-12 45.8 0.1 1.8e-10 40.7 0.1 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PS_Dcarbxylase PF02666.15 KUM55497.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.6 1 1 0 1 1 1 0 Phosphatidylserine decarboxylase Sugar_tr PF00083.24 KUM55498.1 - 2.2e-12 46.6 9.9 2.4e-12 46.5 9.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3593 PF12159.8 KUM55498.1 - 0.12 12.5 1.1 0.48 10.5 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3593) ICL PF00463.21 KUM55500.1 - 1.1e-186 621.4 0.0 1.3e-186 621.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KUM55500.1 - 2.5e-09 36.9 0.0 4.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase KR PF08659.10 KUM55502.1 - 1.1e-12 48.2 0.0 4e-12 46.4 0.0 2.0 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KUM55502.1 - 2.9e-07 30.5 0.1 8.6e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM55502.1 - 0.00064 20.8 0.0 0.0097 17.0 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KUM55502.1 - 0.00099 18.6 0.1 0.0038 16.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KUM55503.1 - 1.6e-09 37.9 0.0 4.6e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 KR domain PP-binding PF00550.25 KUM55503.1 - 9.9e-06 25.8 0.1 2.5e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1102 PF06510.11 KUM55506.1 - 0.17 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) Aminotran_1_2 PF00155.21 KUM55512.1 - 8.1e-40 137.1 0.0 9.5e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HNH_2 PF13391.6 KUM55514.1 - 3.8e-05 23.7 0.0 8.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease CENP-B_dimeris PF09026.10 KUM55514.1 - 3.7 8.0 6.9 8.5 6.8 6.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ubiquitin PF00240.23 KUM55515.1 - 4.4e-135 439.7 20.4 3.3e-33 113.3 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 KUM55515.1 - 6.6e-64 211.7 21.0 2e-15 56.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KUM55515.1 - 8.1e-23 80.7 10.7 0.00043 20.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 KUM55515.1 - 1.7e-16 59.9 3.0 0.027 14.4 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KUM55515.1 - 3.9e-15 56.0 8.2 0.028 14.8 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KUM55515.1 - 2.1e-14 53.6 2.6 0.12 12.4 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KUM55515.1 - 5.6e-13 49.4 1.4 0.37 11.4 0.0 4.2 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KUM55515.1 - 5.2e-11 42.7 0.8 0.52 10.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 KUM55515.1 - 3.7e-07 30.1 24.0 16 5.6 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 KUM55515.1 - 2.9e-06 26.8 0.4 1.8 7.8 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 KUM55515.1 - 3.8e-06 27.0 2.5 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 KUM55515.1 - 7.1e-06 26.3 0.0 30 5.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 KUM55515.1 - 1.2e-05 25.0 4.7 10 6.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain Big_7 PF17957.1 KUM55515.1 - 4e-05 24.3 0.1 52 4.7 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 KUM55515.1 - 0.00014 21.9 4.3 7.1 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KUM55515.1 - 0.00042 19.8 0.0 23 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) YcgR_2 PF12945.7 KUM55515.1 - 0.00091 19.3 6.2 29 4.9 0.1 4.3 4 0 0 4 4 4 0 Flagellar protein YcgR DUF493 PF04359.14 KUM55515.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 KUM55515.1 - 0.0037 16.9 0.0 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 KUM55515.1 - 0.0052 17.4 1.0 1.4e+02 3.1 0.0 4.2 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 KUM55515.1 - 0.0068 16.5 0.0 91 3.3 0.0 4.3 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 KUM55515.1 - 0.11 12.7 5.8 1.1e+02 3.1 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Baculo_p48 PF04878.13 KUM55515.1 - 0.12 11.2 0.0 61 2.4 0.0 3.0 3 0 0 3 3 3 0 Baculovirus P48 protein Tash_PEST PF07708.11 KUM55515.1 - 0.14 12.4 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Myosin_N PF02736.19 KUM55515.1 - 0.23 11.3 6.3 1.1e+02 2.8 0.0 5.2 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain HAMP_N3 PF18575.1 KUM55515.1 - 0.23 11.0 1.5 2e+02 1.6 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 PI3K_p85B PF02192.16 KUM55515.1 - 1.9 8.3 9.3 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain BRAP2 PF07576.12 KUM55516.1 - 3.8e-34 116.9 0.0 6.6e-34 116.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KUM55516.1 - 8.5e-20 70.9 7.1 1.4e-19 70.2 5.4 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KUM55516.1 - 1.4e-08 34.9 9.4 1.4e-08 34.9 9.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KUM55516.1 - 4.6e-06 26.4 9.7 4.6e-06 26.4 9.7 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KUM55516.1 - 0.00011 21.9 4.8 0.00011 21.9 4.8 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KUM55516.1 - 0.0002 21.1 8.8 0.0002 21.1 8.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KUM55516.1 - 0.0003 20.7 8.2 0.0003 20.7 8.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KUM55516.1 - 0.00033 20.4 5.7 0.00033 20.4 5.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KUM55516.1 - 0.0004 20.6 7.3 0.0004 20.6 7.3 2.3 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KUM55516.1 - 0.00043 20.2 5.7 0.00043 20.2 5.7 2.4 2 1 0 2 2 1 1 RING-type zinc-finger zf-RING_6 PF14835.6 KUM55516.1 - 0.0009 19.1 2.3 0.0026 17.6 2.3 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KUM55516.1 - 0.0072 16.4 5.3 0.022 14.8 5.3 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KUM55516.1 - 0.035 14.0 19.9 0.04 13.8 9.9 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 ZapB PF06005.12 KUM55516.1 - 0.11 13.0 4.8 2.4 8.7 0.2 2.7 1 1 1 2 2 2 0 Cell division protein ZapB Lectin_N PF03954.14 KUM55516.1 - 0.9 9.3 5.0 1 9.1 0.4 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain zf-RING_4 PF14570.6 KUM55516.1 - 0.98 9.3 6.9 2.2 8.2 6.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Filament PF00038.21 KUM55516.1 - 2.5 7.6 10.6 1.2 8.6 3.4 2.2 1 1 1 2 2 2 0 Intermediate filament protein DUF3450 PF11932.8 KUM55516.1 - 5.7 6.2 9.0 0.34 10.2 1.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) MutS_V PF00488.21 KUM55520.1 - 9.6e-74 247.5 0.8 1.5e-73 246.8 0.2 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KUM55520.1 - 2.5e-33 115.9 0.7 7e-33 114.5 0.7 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KUM55520.1 - 7.1e-29 100.3 0.0 2.1e-28 98.8 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KUM55520.1 - 3.1e-08 34.0 0.0 1.2e-07 32.1 0.0 2.1 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KUM55520.1 - 0.0015 18.8 0.1 0.0063 16.8 0.1 2.1 1 0 0 1 1 1 1 MutS family domain IV GST_N PF02798.20 KUM55521.1 - 9.6e-11 41.9 0.0 1.7e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KUM55521.1 - 1.1e-08 35.4 0.0 1.8e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KUM55521.1 - 8.7e-08 32.4 0.0 1.9e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KUM55521.1 - 1.3e-06 28.5 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KUM55521.1 - 4.4e-05 23.6 0.0 8.4e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KUM55521.1 - 0.0001 22.2 0.1 0.00022 21.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KUM55521.1 - 0.029 15.0 0.1 0.14 12.8 0.0 2.1 2 1 1 3 3 3 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KUM55521.1 - 0.055 14.2 0.0 0.13 13.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain TPR_10 PF13374.6 KUM55522.1 - 1.1e-86 282.6 5.0 2.1e-11 43.3 0.0 10.5 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.6 KUM55522.1 - 5.9e-71 234.8 28.4 1.5e-14 54.1 0.3 8.7 2 1 7 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.6 KUM55522.1 - 3e-19 67.6 13.1 0.0049 16.8 0.1 9.9 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 KUM55522.1 - 1.3e-11 44.8 5.4 0.93 10.0 0.1 7.5 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KUM55522.1 - 7.8e-11 42.4 16.3 0.15 12.7 0.0 7.6 7 4 1 8 8 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KUM55522.1 - 2.5e-09 37.0 11.9 2e-06 27.4 5.1 3.0 3 1 1 4 4 4 2 MalT-like TPR region TPR_2 PF07719.17 KUM55522.1 - 1.3e-08 34.3 17.0 1.1 9.5 0.0 9.6 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_1 PF00515.28 KUM55522.1 - 7.3e-08 31.9 5.4 0.99 9.3 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_4 PF07721.14 KUM55522.1 - 3.5e-07 30.2 5.1 0.32 11.8 0.1 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat NB-ARC PF00931.22 KUM55522.1 - 4.4e-07 29.4 0.0 1.7e-05 24.2 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain TPR_17 PF13431.6 KUM55522.1 - 5.3e-07 29.6 1.8 6.3 7.4 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat NACHT PF05729.12 KUM55522.1 - 6.9e-06 26.1 0.0 1.6e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KUM55522.1 - 5.4e-05 23.6 0.0 0.0002 21.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain TPR_8 PF13181.6 KUM55522.1 - 0.0023 18.0 6.4 87 3.7 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 KUM55522.1 - 0.084 13.2 4.3 6.7 7.1 0.1 5.1 4 2 2 6 6 5 0 Tetratricopeptide repeat AAA_22 PF13401.6 KUM55522.1 - 0.097 12.9 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KUM55522.1 - 0.11 12.3 0.1 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PPR PF01535.20 KUM55522.1 - 0.13 12.6 0.4 75 3.9 0.0 5.2 7 0 0 7 7 6 0 PPR repeat TPR_14 PF13428.6 KUM55522.1 - 1.9 9.5 19.3 1.3e+02 3.8 0.1 8.6 7 3 3 10 10 8 0 Tetratricopeptide repeat ADH_N_2 PF16884.5 KUM55524.1 - 2.9e-24 85.1 0.0 6.3e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KUM55524.1 - 5e-19 68.6 0.0 1e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM55524.1 - 2.5e-08 35.1 0.0 5.2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Hydrolase_4 PF12146.8 KUM55525.1 - 0.012 14.9 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KUM55525.1 - 0.02 15.5 0.1 0.02 15.5 0.1 2.0 2 1 0 2 2 2 0 Alpha/beta hydrolase family LCAT PF02450.15 KUM55525.1 - 0.021 14.0 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 KUM55525.1 - 0.061 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Mito_carr PF00153.27 KUM55527.1 - 8.4e-63 208.3 2.4 1.1e-22 79.8 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KUM55527.1 - 0.09 11.9 0.0 6.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease RRM_1 PF00076.22 KUM55528.1 - 0.12 12.2 0.0 1.2 9.0 0.0 2.4 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CFEM PF05730.11 KUM55530.1 - 3.6e-11 43.0 11.0 6.8e-11 42.1 11.0 1.4 1 0 0 1 1 1 1 CFEM domain HSDR_N_2 PF13588.6 KUM55532.1 - 0.015 15.3 0.1 0.026 14.5 0.1 1.4 1 1 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) MFS_1 PF07690.16 KUM55534.1 - 2.9e-33 115.3 21.3 4.5e-33 114.6 21.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Toxin_28 PF08115.11 KUM55534.1 - 0.14 12.0 0.5 0.33 10.9 0.5 1.6 1 0 0 1 1 1 0 SFI toxin family Sulfatase PF00884.23 KUM55535.1 - 1.5e-63 215.1 0.7 2e-63 214.7 0.7 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KUM55535.1 - 0.0019 17.8 2.1 0.03 13.9 2.1 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KUM55535.1 - 0.0044 17.2 0.1 0.0086 16.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) bZIP_1 PF00170.21 KUM55536.1 - 0.0079 16.3 0.7 0.018 15.1 0.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor Atg14 PF10186.9 KUM55536.1 - 0.17 10.9 2.4 0.24 10.5 2.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 adh_short PF00106.25 KUM55537.1 - 2.5e-23 82.6 0.1 2.1e-21 76.3 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM55537.1 - 1.1e-10 41.4 0.0 1e-08 35.0 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM55537.1 - 2.3e-07 30.9 0.1 4.5e-07 29.9 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KUM55537.1 - 0.00027 20.5 0.0 0.00037 20.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KUM55537.1 - 0.029 13.5 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 KUM55538.1 - 4.5e-09 36.4 0.2 7.9e-09 35.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM55538.1 - 6.4e-08 32.5 0.0 3.4e-07 30.1 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KUM55538.1 - 0.11 13.5 0.0 0.26 12.3 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Zn_clus PF00172.18 KUM55541.1 - 6.8e-09 35.7 12.5 1e-08 35.1 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM55541.1 - 1e-08 34.5 0.0 1.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1330 PF07045.11 KUM55542.1 - 0.0092 16.3 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1330) Phage_T7_Capsid PF05396.11 KUM55542.1 - 0.17 12.3 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 Phage T7 capsid assembly protein p450 PF00067.22 KUM55545.1 - 2.1e-48 165.2 0.0 2.8e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_11 PF00457.17 KUM55546.1 - 2.1e-75 252.2 10.9 2.5e-75 252.0 10.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 ADH_zinc_N PF00107.26 KUM55548.1 - 4.8e-18 65.4 1.0 1e-17 64.4 1.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM55548.1 - 8e-18 64.3 0.3 2.2e-17 62.9 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PQQ PF01011.21 KUM55548.1 - 0.02 14.8 0.1 0.058 13.4 0.1 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat AlaDh_PNT_C PF01262.21 KUM55548.1 - 0.024 13.9 1.8 0.044 13.1 1.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 KUM55548.1 - 0.072 13.4 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain zf-Tim10_DDP PF02953.15 KUM55549.1 - 6.2e-18 64.2 8.0 8.9e-18 63.7 8.0 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 KUM55549.1 - 0.0019 17.9 5.3 0.11 12.2 0.7 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Aminotran_1_2 PF00155.21 KUM55550.1 - 4.4e-06 26.1 0.0 5.3e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II zf-RING_2 PF13639.6 KUM55551.1 - 1.3e-13 51.0 5.7 2.5e-13 50.1 5.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KUM55551.1 - 5.2e-10 38.9 3.2 9.2e-10 38.1 3.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KUM55551.1 - 8.2e-09 35.2 6.3 1.3e-08 34.5 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM55551.1 - 3.4e-08 33.2 4.2 6.5e-08 32.3 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KUM55551.1 - 2.9e-07 30.7 7.6 1e-06 28.9 7.6 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KUM55551.1 - 5.4e-05 23.1 2.1 5.4e-05 23.1 2.1 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KUM55551.1 - 5.9e-05 22.9 2.5 5.9e-05 22.9 2.5 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KUM55551.1 - 8.6e-05 22.3 1.8 8.6e-05 22.3 1.8 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KUM55551.1 - 0.00011 22.0 6.9 0.0013 18.6 7.1 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KUM55551.1 - 0.00013 21.9 2.4 0.00032 20.7 2.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KUM55551.1 - 0.00065 19.4 4.0 0.0012 18.5 4.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KUM55551.1 - 0.0065 16.6 3.2 0.0065 16.6 3.2 2.0 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KUM55551.1 - 0.033 14.5 1.8 0.059 13.7 1.8 1.4 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 KUM55551.1 - 0.14 11.8 1.9 0.31 10.7 1.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 KUM55551.1 - 0.24 11.3 2.5 0.27 11.2 0.6 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 KUM55551.1 - 5.2 7.3 9.3 2.6 8.3 5.5 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain GPI-anchored PF10342.9 KUM55558.1 - 8.8e-24 84.1 0.1 8.8e-24 84.1 0.1 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Aldedh PF00171.22 KUM55559.1 - 3.2e-122 408.4 1.3 4.1e-122 408.0 1.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldo_ket_red PF00248.21 KUM55560.1 - 2.3e-34 118.9 0.0 3e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Albumin_I_a PF16720.5 KUM55560.1 - 0.048 13.6 0.1 0.2 11.6 0.1 2.1 2 0 0 2 2 2 0 Albumin I chain a MRC1 PF09444.10 KUM55563.1 - 0.16 12.5 0.2 0.23 12.0 0.2 1.2 1 0 0 1 1 1 0 MRC1-like domain Fungal_trans_2 PF11951.8 KUM55565.1 - 8.2e-36 123.6 0.0 1.1e-35 123.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM55565.1 - 2.5e-08 33.9 9.4 4.3e-08 33.1 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fmp27_GFWDK PF10347.9 KUM55565.1 - 0.086 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain adh_short_C2 PF13561.6 KUM55566.1 - 9e-62 208.7 0.0 1.2e-61 208.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM55566.1 - 2.6e-50 170.6 0.1 3.3e-50 170.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM55566.1 - 2.7e-05 24.2 0.1 6.4e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM55566.1 - 0.027 13.9 0.1 0.06 12.8 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CM_2 PF01817.21 KUM55567.1 - 1.7e-12 47.5 0.1 2.1e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 Chorismate mutase type II Nucleic_acid_bd PF13820.6 KUM55567.1 - 0.038 13.8 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative nucleic acid-binding region Osmo_CC PF08946.10 KUM55567.1 - 0.049 13.9 0.2 0.077 13.3 0.2 1.3 1 0 0 1 1 1 0 Osmosensory transporter coiled coil BAR PF03114.18 KUM55567.1 - 0.19 11.4 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 BAR domain Peptidase_M24 PF00557.24 KUM55568.1 - 2.9e-20 72.8 0.0 3.6e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24 PF00557.24 KUM55569.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase family M24 Fungal_trans PF04082.18 KUM55570.1 - 6.7e-22 77.8 0.2 8e-22 77.5 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain GATA PF00320.27 KUM55571.1 - 9.5e-16 57.1 5.3 1.6e-15 56.4 5.3 1.4 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 KUM55571.1 - 0.12 12.5 0.5 0.24 11.6 0.5 1.4 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 KUM55571.1 - 0.12 12.6 1.6 0.25 11.7 1.6 1.5 1 0 0 1 1 1 0 zinc-ribbon zf-C2H2_jaz PF12171.8 KUM55574.1 - 1.7e-23 82.3 61.8 6.3e-05 23.1 2.4 10.1 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KUM55574.1 - 1.2e-20 73.1 64.3 0.00027 21.2 2.7 10.1 10 0 0 10 10 10 7 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KUM55574.1 - 1e-16 60.1 54.2 0.12 13.3 1.2 10.6 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KUM55574.1 - 5.8e-15 55.5 70.4 0.013 15.8 2.9 9.7 1 1 8 9 9 9 8 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KUM55574.1 - 3.7e-11 42.8 66.4 0.12 12.9 0.2 10.6 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 KUM55574.1 - 2.9e-06 27.0 17.9 1.3 9.0 0.1 6.8 6 0 0 6 6 6 4 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KUM55574.1 - 0.00037 20.4 51.1 0.25 11.4 0.8 9.9 10 0 0 10 10 10 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KUM55574.1 - 0.025 15.0 46.8 0.2 12.2 0.8 10.1 10 0 0 10 10 10 0 Zinc-finger double domain zf-Sec23_Sec24 PF04810.15 KUM55574.1 - 2.4 8.3 15.8 2.8 8.1 0.1 5.0 5 0 0 5 5 5 0 Sec23/Sec24 zinc finger Pkinase PF00069.25 KUM55576.1 - 6e-65 219.2 0.0 9.4e-65 218.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM55576.1 - 2.1e-27 96.1 0.0 3.5e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KUM55576.1 - 0.013 14.5 0.2 0.02 13.8 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KUM55576.1 - 0.045 13.1 0.5 0.19 11.0 0.3 2.0 1 1 1 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KUM55576.1 - 0.076 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FolB PF02152.18 KUM55578.1 - 1.6e-25 89.8 0.0 1.2e-21 77.4 0.1 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase zf-C2H2 PF00096.26 KUM55579.1 - 3.9e-06 27.0 0.9 0.056 13.9 0.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM55579.1 - 5.1e-05 23.8 0.4 0.24 12.4 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KUM55579.1 - 0.1 13.1 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 KUM55579.1 - 0.14 12.2 0.5 0.83 9.7 0.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 KUM55579.1 - 0.16 12.5 0.2 0.44 11.1 0.0 1.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain LSM PF01423.22 KUM55582.1 - 8e-18 63.9 0.1 1e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KUM55582.1 - 0.0022 18.1 0.1 0.003 17.7 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain PetM PF08041.11 KUM55583.1 - 0.24 11.0 3.3 0.51 10.0 3.3 1.5 1 1 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 RNase_H PF00075.24 KUM55584.1 - 2.7e-05 24.4 0.0 3.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 RNase H TruD PF01142.18 KUM55585.1 - 7.3e-67 226.0 4.4 7.2e-62 209.5 1.5 3.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) DUF4448 PF14610.6 KUM55586.1 - 3.7e-06 26.9 0.0 7.7e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) SKG6 PF08693.10 KUM55586.1 - 9.5e-06 24.9 4.5 0.00026 20.3 0.3 3.4 3 0 0 3 3 3 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 KUM55586.1 - 0.011 15.7 0.4 0.011 15.7 0.4 2.3 2 0 0 2 2 2 0 TMEM154 protein family Mid2 PF04478.12 KUM55586.1 - 0.046 13.5 0.1 0.085 12.7 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF3188 PF11384.8 KUM55586.1 - 0.058 13.1 0.9 0.14 11.9 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Amino_oxidase PF01593.24 KUM55587.1 - 1.5e-40 139.9 0.1 2.7e-40 139.0 0.1 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KUM55587.1 - 4.1e-05 23.7 0.4 0.00013 22.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KUM55587.1 - 0.008 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HAD_2 PF13419.6 KUM55588.1 - 2.8e-09 37.3 0.0 3.5e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KUM55588.1 - 5.7e-07 30.0 0.0 6.8e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KUM55588.1 - 0.0002 21.4 0.0 0.00034 20.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HTH_1 PF00126.27 KUM55588.1 - 0.028 14.4 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF3226 PF11536.8 KUM55588.1 - 0.057 13.1 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3226) Zn_clus PF00172.18 KUM55590.1 - 8.5e-10 38.6 8.5 1.4e-09 37.9 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kelch_5 PF13854.6 KUM55591.1 - 7.5e-15 54.5 3.7 2.9e-12 46.3 0.4 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 KUM55591.1 - 6.5e-07 28.8 0.4 0.0058 16.2 0.1 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KUM55591.1 - 0.00016 21.6 1.0 0.66 10.0 0.1 4.7 5 0 0 5 5 5 1 Galactose oxidase, central domain DUF4381 PF14316.6 KUM55591.1 - 0.0022 18.2 0.1 0.0042 17.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) Kelch_6 PF13964.6 KUM55591.1 - 0.004 17.4 1.4 0.073 13.4 0.2 3.4 4 0 0 4 4 4 1 Kelch motif Phage_holin_2_4 PF16082.5 KUM55591.1 - 0.0087 15.8 0.1 0.024 14.4 0.1 1.7 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like PTP_tm PF18861.1 KUM55591.1 - 0.036 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J SARAF PF06682.12 KUM55591.1 - 0.057 13.1 6.2 0.097 12.3 6.2 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF3318 PF11780.8 KUM55591.1 - 0.094 12.7 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) MASE1 PF05231.14 KUM55591.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 MASE1 Aminotran_3 PF00202.21 KUM55592.1 - 1.3e-36 126.1 0.0 3.6e-15 55.5 0.0 3.2 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.6 KUM55592.1 - 3.4e-22 79.3 0.0 7.3e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Aminotran_1_2 PF00155.21 KUM55594.1 - 3.2e-35 122.0 0.0 4e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 KUM55594.1 - 7.9e-05 21.6 0.0 0.00012 20.9 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 KUM55594.1 - 0.002 17.1 0.0 0.4 9.6 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_3 PF00202.21 KUM55594.1 - 0.024 13.3 0.0 0.041 12.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III Cys_Met_Meta_PP PF01053.20 KUM55594.1 - 0.14 10.7 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme HNH_2 PF13391.6 KUM55595.1 - 8.3e-12 45.1 1.6 1.2e-11 44.5 0.5 1.9 2 0 0 2 2 2 1 HNH endonuclease MFS_1 PF07690.16 KUM55596.1 - 1.6e-30 106.2 49.3 1.6e-30 106.2 49.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM55596.1 - 1.4e-08 34.1 39.8 8.3e-08 31.5 13.2 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter Glyco_transf_20 PF00982.21 KUM55597.1 - 1.3e-150 502.3 0.0 1.6e-150 501.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 KUM55597.1 - 0.00045 20.7 0.0 0.0014 19.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KUM55597.1 - 0.0061 16.9 0.1 0.017 15.5 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KUM55597.1 - 0.011 15.3 0.7 0.33 10.5 0.3 2.9 3 1 0 3 3 3 0 Glycosyl transferases group 1 DUF693 PF05113.13 KUM55597.1 - 0.034 13.4 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF693) AFG1_ATPase PF03969.16 KUM55597.1 - 0.18 10.6 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase FAD_binding_3 PF01494.19 KUM55599.1 - 1.6e-79 267.7 0.0 1.9e-79 267.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KUM55599.1 - 1e-05 25.6 0.0 3.5e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KUM55599.1 - 0.00015 21.0 0.0 0.00041 19.5 0.0 1.7 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 KUM55599.1 - 0.00016 21.4 0.4 0.0005 19.8 0.2 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM55599.1 - 0.00021 20.6 0.0 0.0014 17.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM55599.1 - 0.0012 18.0 0.0 0.0025 17.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KUM55599.1 - 0.0018 17.0 0.0 0.0036 16.1 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KUM55599.1 - 0.0021 18.6 0.0 0.03 14.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KUM55599.1 - 0.01 14.9 0.1 0.023 13.7 0.1 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KUM55599.1 - 0.022 14.0 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KUM55599.1 - 0.12 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding ApbA PF02558.16 KUM55599.1 - 0.13 11.9 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KUM55599.1 - 0.2 10.9 0.1 0.37 10.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Phosphoesterase PF04185.14 KUM55600.1 - 7.2e-59 199.8 1.0 1.2e-58 199.0 1.0 1.4 1 1 0 1 1 1 1 Phosphoesterase family Atrophin-1 PF03154.15 KUM55601.1 - 3.7 5.7 7.8 4 5.6 7.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family WD40 PF00400.32 KUM55602.1 - 3.6e-147 473.8 31.2 2.7e-12 47.0 0.0 13.1 13 0 0 13 13 13 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM55602.1 - 1.6e-68 227.0 0.0 2.5e-07 30.9 0.0 11.9 1 1 10 11 11 11 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KUM55602.1 - 2.7e-30 105.5 2.7 0.0088 15.0 0.0 11.5 1 1 11 12 12 12 7 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KUM55602.1 - 1.6e-17 63.8 0.0 0.13 11.5 0.0 8.5 1 1 6 9 9 9 5 WD40-like domain eIF2A PF08662.11 KUM55602.1 - 7.3e-16 58.6 0.0 0.00021 21.2 0.0 5.1 1 1 5 6 6 6 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KUM55602.1 - 2.2e-14 52.9 0.2 8.3 6.5 0.0 10.9 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat DUF642 PF04862.12 KUM55602.1 - 3.2e-11 43.3 0.5 1.1 9.1 0.0 7.5 1 1 6 8 8 8 2 Protein of unknown function (DUF642) IKI3 PF04762.12 KUM55602.1 - 1.9e-08 32.8 5.3 0.14 10.1 0.2 4.9 2 2 1 4 4 4 2 IKI3 family Peptidase_S9_N PF02897.15 KUM55602.1 - 6.7e-08 31.7 2.5 0.32 9.8 0.0 6.3 4 3 1 5 5 5 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Cytochrom_D1 PF02239.16 KUM55602.1 - 8.8e-08 31.1 0.2 2.8 6.4 0.0 4.8 1 1 2 4 4 4 3 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 KUM55602.1 - 1.3e-07 31.1 15.0 2.4 7.9 0.0 9.3 10 0 0 10 10 9 2 Proteasome subunit A N-terminal signature Nbas_N PF15492.6 KUM55602.1 - 2.6e-07 30.3 5.9 8.1 5.7 0.0 8.9 1 1 9 11 11 11 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 KUM55602.1 - 2.8e-06 26.4 5.6 0.14 10.9 0.0 5.8 1 1 6 7 7 7 2 Nup133 N terminal like Frtz PF11768.8 KUM55602.1 - 7.8e-06 24.5 0.0 6.8 4.9 0.0 5.9 1 1 4 7 7 7 1 WD repeat-containing and planar cell polarity effector protein Fritz Robl_LC7 PF03259.17 KUM55602.1 - 1.7e-05 24.5 1.5 20 5.0 0.0 7.2 9 0 0 9 9 8 0 Roadblock/LC7 domain MORN_2 PF07661.13 KUM55602.1 - 2e-05 24.3 0.0 31 5.2 0.0 7.7 8 0 0 8 8 8 0 MORN repeat variant WXG100 PF06013.12 KUM55602.1 - 4.2e-05 23.7 0.0 63 3.9 0.0 7.2 9 0 0 9 9 9 0 Proteins of 100 residues with WXG PALB2_WD40 PF16756.5 KUM55602.1 - 7e-05 21.9 4.8 6.6 5.6 0.0 6.8 2 2 5 8 8 8 1 Partner and localizer of BRCA2 WD40 domain RAB3GAP2_N PF14655.6 KUM55602.1 - 0.00023 20.6 0.0 0.9 8.7 0.0 5.5 4 2 4 9 9 9 1 Rab3 GTPase-activating protein regulatory subunit N-terminus CNH PF00780.22 KUM55602.1 - 0.015 14.9 0.0 6.9 6.2 0.0 4.9 6 3 3 9 9 9 0 CNH domain NCOA_u2 PF16665.5 KUM55602.1 - 0.023 15.0 6.8 7.5 6.9 0.0 5.0 3 2 0 5 5 5 0 Unstructured region on nuclear receptor coactivator protein DUF4072 PF13284.6 KUM55602.1 - 0.078 13.4 0.1 27 5.3 0.0 4.1 6 0 0 6 6 3 0 Domain of unknown function (DUF4072) HARP PF07443.13 KUM55602.1 - 0.16 11.7 0.0 1.2 8.8 0.0 2.6 3 0 0 3 3 2 0 HepA-related protein (HARP) nos_propeller PF18764.1 KUM55602.1 - 0.26 11.2 0.7 73 3.4 0.0 4.7 7 0 0 7 7 7 0 Nitrous oxide reductase propeller repeat NACHT PF05729.12 KUM55603.1 - 0.004 17.1 0.6 0.0065 16.4 0.2 1.6 2 0 0 2 2 2 1 NACHT domain KAP_NTPase PF07693.14 KUM55603.1 - 0.1 11.8 0.6 0.15 11.3 0.6 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Helo_like_N PF17111.5 KUM55604.1 - 1.4e-07 31.1 0.1 1.6e-07 30.9 0.1 1.0 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KUM55604.1 - 0.00024 21.3 0.2 0.00029 21.0 0.2 1.1 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NPV_P10 PF05531.12 KUM55604.1 - 0.0021 18.5 2.9 0.68 10.4 0.2 2.2 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein CREPT PF16566.5 KUM55604.1 - 0.0081 16.3 0.1 0.011 15.9 0.1 1.3 1 1 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour PLU-1 PF08429.11 KUM55604.1 - 0.032 13.4 0.2 0.04 13.1 0.2 1.0 1 0 0 1 1 1 0 PLU-1-like protein JAKMIP_CC3 PF16034.5 KUM55604.1 - 0.057 13.4 0.2 0.072 13.0 0.2 1.1 1 0 0 1 1 1 0 JAKMIP CC3 domain Cytochrome-c551 PF10643.9 KUM55604.1 - 0.072 12.7 0.0 0.094 12.3 0.0 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Cellulase PF00150.18 KUM55606.1 - 1.5e-18 67.2 6.5 2.5e-18 66.5 6.5 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KUM55606.1 - 6.4e-12 45.2 8.7 6.4e-12 45.2 8.7 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 KUM55606.1 - 4.7e-05 22.6 0.2 0.00011 21.4 0.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KUM55606.1 - 0.0053 16.1 0.1 0.012 15.0 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase Fungal_trans_2 PF11951.8 KUM55607.1 - 6.6e-08 31.8 0.8 9e-08 31.3 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1400 PF07176.11 KUM55609.1 - 0.17 12.2 0.6 1.7 9.0 0.1 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) RCR PF12273.8 KUM55610.1 - 1.5e-20 74.0 15.2 1.9e-20 73.7 15.2 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SARAF PF06682.12 KUM55610.1 - 0.09 12.4 0.2 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SLD5_C PF16922.5 KUM55611.1 - 1.4e-14 54.0 1.1 2.5e-14 53.2 1.1 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KUM55611.1 - 6.1e-09 36.3 0.2 8.7e-09 35.8 0.2 1.3 1 0 0 1 1 1 1 GINS complex protein RNase_H PF00075.24 KUM55612.1 - 6.3e-11 42.6 0.0 8.5e-10 39.0 0.0 2.4 1 1 0 1 1 1 1 RNase H MFS_1 PF07690.16 KUM55613.1 - 7.8e-33 113.8 24.5 1.1e-32 113.4 24.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.13 KUM55614.1 - 2.1e-96 323.0 2.2 2.4e-96 322.8 2.2 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KUM55614.1 - 0.0037 15.8 0.1 0.0048 15.4 0.1 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 adh_short_C2 PF13561.6 KUM55615.1 - 8.5e-13 48.4 0.0 9.9e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM55615.1 - 0.027 13.9 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase DHDPS PF00701.22 KUM55616.1 - 3.6e-41 140.8 0.0 4.1e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CbiD PF01888.17 KUM55616.1 - 0.031 13.6 0.2 0.068 12.5 0.2 1.5 2 0 0 2 2 2 0 CbiD Ank_2 PF12796.7 KUM55617.1 - 1.1e-15 58.0 0.3 0.022 15.3 0.0 4.9 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM55617.1 - 1.6e-10 41.3 0.4 0.014 16.0 0.0 6.4 5 1 2 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM55617.1 - 9.3e-06 25.6 0.3 5.2 8.0 0.0 6.9 8 0 0 8 8 8 1 Ankyrin repeat Helo_like_N PF17111.5 KUM55617.1 - 3.1e-05 23.4 2.7 0.00023 20.6 2.6 2.3 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank PF00023.30 KUM55617.1 - 8.5e-05 22.8 2.0 4.7 7.8 0.0 6.4 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 KUM55617.1 - 0.00023 21.4 0.1 4.1 7.8 0.0 5.0 5 1 1 6 6 6 1 Ankyrin repeats (many copies) SesA PF17107.5 KUM55617.1 - 0.04 14.1 1.5 0.15 12.2 0.2 2.3 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF5428 PF17493.2 KUM55617.1 - 0.045 14.2 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5428) TPR_19 PF14559.6 KUM55617.1 - 0.085 13.4 0.0 2.2 8.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1524 PF07510.11 KUM55618.1 - 6.5e-10 39.0 0.0 8e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) MFS_1 PF07690.16 KUM55619.1 - 1.3e-28 100.0 23.4 1.7e-28 99.6 23.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Oxidored_FMN PF00724.20 KUM55621.1 - 2.5e-61 207.8 0.0 7.7e-61 206.2 0.0 1.7 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KUM55621.1 - 0.043 13.2 0.0 0.35 10.3 0.0 2.2 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel FMN_dh PF01070.18 KUM55623.1 - 5.3e-89 298.7 0.1 6.3e-89 298.4 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KUM55623.1 - 7.4e-06 25.3 0.0 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KUM55623.1 - 3.4e-05 23.0 0.1 0.00034 19.7 0.0 2.4 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KUM55623.1 - 0.022 14.2 0.1 0.043 13.2 0.1 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 KUM55623.1 - 0.054 12.9 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF3716 PF12511.8 KUM55626.1 - 4.6e-10 39.4 4.4 6.9e-10 38.8 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF969 PF06149.12 KUM55626.1 - 0.13 11.7 0.1 0.22 10.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF969) Y_phosphatase2 PF03162.13 KUM55628.1 - 0.14 11.7 0.0 0.63 9.6 0.0 1.8 1 1 0 1 1 1 0 Tyrosine phosphatase family Ribonuc_L-PSP PF01042.21 KUM55629.1 - 4.9e-35 120.2 0.0 5.4e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP ADH_zinc_N PF00107.26 KUM55630.1 - 2.7e-11 43.5 0.0 5.2e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM55630.1 - 1e-05 26.6 0.0 1.9e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM55630.1 - 0.00037 20.3 0.0 0.002 18.0 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Ank_2 PF12796.7 KUM55631.1 - 9.2e-45 151.1 6.6 2.5e-11 44.0 0.3 6.4 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM55631.1 - 1.9e-41 139.9 6.6 5.7e-07 30.0 0.0 7.6 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 KUM55631.1 - 5.5e-31 105.6 22.5 0.00022 21.5 0.1 10.1 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 KUM55631.1 - 7.6e-30 102.6 11.4 0.0013 18.9 0.0 9.3 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM55631.1 - 2.2e-26 89.0 4.8 0.076 13.6 0.0 11.3 12 0 0 12 12 11 6 Ankyrin repeat NACHT PF05729.12 KUM55631.1 - 3.5e-14 53.1 0.0 6.5e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 KUM55631.1 - 1e-12 47.8 0.0 3.1e-12 46.3 0.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.6 KUM55631.1 - 1.8e-07 31.5 0.0 5e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KUM55631.1 - 0.00013 22.4 0.0 0.00044 20.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KUM55631.1 - 0.014 15.9 0.0 0.038 14.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KUM55631.1 - 0.025 15.0 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 KUM55631.1 - 0.078 12.2 0.3 2.2 7.4 0.4 2.2 1 1 1 2 2 2 0 KAP family P-loop domain DUF1843 PF08898.10 KUM55631.1 - 0.49 10.9 6.7 12 6.5 0.1 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) MMR_HSR1 PF01926.23 KUM55632.1 - 7.2e-10 39.0 1.4 2.4e-09 37.3 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KUM55632.1 - 3.7e-05 23.2 0.0 3.7e-05 23.2 0.0 1.9 2 0 0 2 2 1 1 AIG1 family AAA_18 PF13238.6 KUM55632.1 - 5.9e-05 23.6 0.4 0.00016 22.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KUM55632.1 - 7.9e-05 22.8 12.0 0.011 15.8 0.0 3.8 2 2 1 3 3 2 2 Dynamin family RsgA_GTPase PF03193.16 KUM55632.1 - 0.00011 22.1 2.2 0.00018 21.5 0.0 2.3 2 2 1 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 KUM55632.1 - 0.0077 16.8 4.2 0.021 15.4 0.0 2.6 2 1 0 2 2 2 1 ABC transporter FeoB_N PF02421.18 KUM55632.1 - 0.021 14.4 0.0 0.06 12.9 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.6 KUM55632.1 - 0.032 14.5 2.7 1.3 9.2 0.1 3.1 3 0 0 3 3 3 0 AAA domain Allexi_40kDa PF05549.11 KUM55632.1 - 0.033 13.7 3.5 0.051 13.1 3.5 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Spore_IV_A PF09547.10 KUM55632.1 - 0.041 12.8 6.4 0.12 11.3 0.0 2.1 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) IIGP PF05049.13 KUM55632.1 - 0.058 12.5 0.0 0.058 12.5 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Viral_helicase1 PF01443.18 KUM55632.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KUM55632.1 - 0.1 12.9 0.0 0.34 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KUM55632.1 - 0.12 12.5 0.2 0.12 12.5 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_29 PF13555.6 KUM55632.1 - 0.15 11.8 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain YPEB PF14620.6 KUM55632.1 - 0.21 10.9 8.6 0.31 10.4 8.6 1.1 1 0 0 1 1 1 0 YpeB sporulation dNK PF01712.19 KUM55632.1 - 0.22 11.4 3.3 5.9 6.7 0.0 3.2 3 0 0 3 3 3 0 Deoxynucleoside kinase DivIVA PF05103.13 KUM55632.1 - 0.31 11.1 13.8 0.7 10.0 13.8 1.6 1 0 0 1 1 1 0 DivIVA protein SRP54 PF00448.22 KUM55632.1 - 0.37 10.4 2.8 0.57 9.8 0.1 2.4 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain FAM92 PF06730.11 KUM55632.1 - 0.53 9.7 8.5 1.6 8.1 8.5 1.7 1 1 0 1 1 1 0 FAM92 protein Exonuc_VII_L PF02601.15 KUM55632.1 - 0.79 9.2 8.6 1.2 8.6 8.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6_N PF17675.1 KUM55632.1 - 1.3 9.5 21.2 2.9 8.4 21.2 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 KUM55632.1 - 1.4 9.0 9.6 3.1 7.9 9.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FlgN PF05130.12 KUM55632.1 - 2.1 8.9 16.4 3.7 8.1 16.4 1.4 1 0 0 1 1 1 0 FlgN protein SBDS_C PF09377.10 KUM55632.1 - 4 7.5 5.9 1.1 9.3 2.1 1.9 2 0 0 2 2 2 0 SBDS protein C-terminal domain Spc7 PF08317.11 KUM55632.1 - 4.6 6.0 22.6 3 6.7 14.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Erp_C PF06780.11 KUM55632.1 - 6.5 6.8 12.6 0.43 10.6 5.0 2.4 2 1 1 3 3 3 0 Erp protein C-terminus Beta-lactamase PF00144.24 KUM55633.1 - 4.4e-40 137.9 0.0 6.5e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase TPMT PF05724.11 KUM55634.1 - 1.1e-27 97.2 0.0 1.5e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 KUM55634.1 - 5e-07 29.7 0.0 6.5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM55634.1 - 6.2e-07 30.0 0.0 2.4e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM55634.1 - 1.2e-06 29.2 0.0 8.2e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM55634.1 - 1.4e-06 29.0 0.0 3.3e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM55634.1 - 9.1e-06 25.5 0.1 8.3e-05 22.4 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KUM55634.1 - 0.0076 15.7 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB N2227 PF07942.12 KUM55634.1 - 0.03 13.5 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein AdoMet_MTase PF07757.13 KUM55634.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Thiolase_N PF00108.23 KUM55635.1 - 4.8e-64 216.2 1.0 8.6e-64 215.4 1.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KUM55635.1 - 1.9e-42 143.8 0.1 4.2e-42 142.7 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KUM55635.1 - 0.0028 17.4 1.4 0.11 12.4 0.2 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KUM55635.1 - 0.0031 17.1 1.3 0.011 15.3 1.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 KUM55635.1 - 0.078 13.1 0.0 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SasG_E PF17041.5 KUM55635.1 - 0.083 12.9 0.6 0.25 11.4 0.6 1.8 1 0 0 1 1 1 0 E domain AMP-binding PF00501.28 KUM55636.1 - 3.5e-59 200.5 0.0 4.7e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM55636.1 - 0.0014 19.5 0.0 0.0038 18.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RhoGAP PF00620.27 KUM55638.1 - 4.6e-37 127.2 0.0 7.6e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CoA_binding_3 PF13727.6 KUM55639.1 - 0.13 12.3 2.9 0.89 9.5 0.1 2.2 1 1 1 2 2 2 0 CoA-binding domain Stevor PF17410.2 KUM55639.1 - 0.23 11.0 3.4 0.42 10.1 3.4 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame MFS_1 PF07690.16 KUM55641.1 - 2.3e-18 66.2 20.8 2.8e-18 66.0 20.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KUM55642.1 - 4e-26 91.8 16.4 5.1e-26 91.4 16.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM55642.1 - 7.8e-11 41.5 5.0 1.3e-10 40.8 5.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter UL42 PF17638.2 KUM55642.1 - 0.00035 20.5 0.5 0.00092 19.2 0.5 1.7 1 0 0 1 1 1 1 HCMV UL42 TRI12 PF06609.13 KUM55642.1 - 0.0071 14.8 2.2 0.0093 14.4 2.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2631 PF10939.8 KUM55642.1 - 0.36 10.7 2.1 0.97 9.3 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2631) HATPase_c PF02518.26 KUM55643.1 - 1.2e-20 74.1 0.0 2.1e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KUM55643.1 - 3.4e-20 72.3 0.1 5.9e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KUM55643.1 - 3.1e-13 49.5 0.0 9.2e-13 48.0 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain FTR1 PF03239.14 KUM55645.1 - 2e-89 299.8 5.0 2.4e-89 299.5 5.0 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family YfdX PF10938.8 KUM55645.1 - 0.064 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 YfdX protein DUF5305 PF17231.2 KUM55645.1 - 0.096 12.1 0.3 9.4 5.6 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF1043 PF06295.12 KUM55645.1 - 0.36 10.8 1.1 24 4.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Phage_holin_3_6 PF07332.11 KUM55645.1 - 2.2 8.3 10.4 1.5 8.9 0.2 2.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III LptF_LptG PF03739.14 KUM55645.1 - 3.3 6.5 8.1 0.18 10.6 1.8 2.0 2 1 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Cu-oxidase_2 PF07731.14 KUM55646.1 - 4.3e-47 159.3 7.4 1.7e-41 141.1 0.5 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KUM55646.1 - 2e-41 140.7 7.2 6.4e-39 132.6 1.9 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KUM55646.1 - 1.7e-34 119.2 3.4 1.2e-31 110.0 0.5 3.2 3 0 0 3 3 3 2 Multicopper oxidase PPC PF04151.15 KUM55646.1 - 0.27 12.4 2.3 1.7 9.8 0.0 3.1 3 1 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain LacI PF00356.21 KUM55647.1 - 0.22 11.4 0.1 0.22 11.4 0.1 1.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family DUF4680 PF15730.5 KUM55647.1 - 0.66 10.3 2.1 0.75 10.1 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) DUF4968 PF16338.5 KUM55648.1 - 0.051 13.9 0.4 0.062 13.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) TPR_1 PF00515.28 KUM55649.1 - 1.3e-37 126.1 12.3 1.7e-08 33.9 0.7 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 KUM55649.1 - 5.9e-36 119.7 9.2 3.8e-06 26.6 0.4 7.9 7 0 0 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.31 KUM55649.1 - 6.9e-27 93.4 1.9 3e-26 91.3 1.9 2.2 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 KUM55649.1 - 1.5e-20 73.5 17.3 6.6e-05 23.3 0.0 6.3 3 3 4 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KUM55649.1 - 5.1e-20 70.0 10.4 9.5e-06 25.4 0.4 8.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KUM55649.1 - 4.6e-19 68.8 5.0 2.5e-07 31.2 0.1 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KUM55649.1 - 7.6e-19 66.8 6.5 0.071 14.0 0.1 8.2 3 3 4 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 KUM55649.1 - 1.8e-18 65.9 17.6 1.9e-08 33.8 0.9 7.6 5 2 3 8 8 8 5 TPR repeat ANAPC3 PF12895.7 KUM55649.1 - 4.1e-15 55.8 6.4 1e-05 25.7 0.0 5.3 2 2 4 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KUM55649.1 - 4.6e-15 54.8 15.4 0.003 17.8 0.8 7.1 9 0 0 9 9 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 KUM55649.1 - 4.5e-13 49.3 6.2 0.0027 18.0 0.5 6.7 4 2 1 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KUM55649.1 - 2.5e-12 45.9 2.7 0.33 11.1 0.1 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KUM55649.1 - 4.4e-11 42.8 3.3 0.014 15.6 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KUM55649.1 - 2.9e-09 37.0 15.2 0.29 11.9 0.0 7.8 7 2 1 9 9 6 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KUM55649.1 - 1e-08 35.1 10.3 0.0095 16.0 0.3 5.7 4 2 2 6 6 6 3 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 KUM55649.1 - 1.9e-06 27.3 10.7 0.034 13.4 0.2 5.0 3 1 1 5 5 5 3 Tetratricopeptide repeat BTAD PF03704.17 KUM55649.1 - 0.0017 18.8 2.3 0.63 10.5 0.4 4.0 2 1 2 4 4 4 1 Bacterial transcriptional activator domain DUF4919 PF16266.5 KUM55649.1 - 0.0017 18.3 3.5 0.61 10.0 0.3 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4919) DUF928 PF06051.12 KUM55649.1 - 0.002 18.0 0.9 0.3 10.9 0.0 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF928) Alkyl_sulf_dimr PF14863.6 KUM55649.1 - 0.0023 18.4 5.2 7.4 7.0 0.0 4.6 2 2 3 5 5 5 0 Alkyl sulfatase dimerisation DUF3856 PF12968.7 KUM55649.1 - 0.0044 17.1 5.8 5 7.2 0.7 5.6 4 2 1 5 5 5 1 Domain of Unknown Function (DUF3856) TPR_4 PF07721.14 KUM55649.1 - 0.005 17.3 1.1 2.2 9.2 0.0 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 KUM55649.1 - 0.0068 16.5 0.3 0.55 10.4 0.0 4.0 5 1 0 5 5 4 1 Rapsyn N-terminal myristoylation and linker region TPR_10 PF13374.6 KUM55649.1 - 0.018 14.9 13.4 3.6 7.6 0.3 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF5588 PF17826.1 KUM55649.1 - 0.018 14.0 2.8 0.084 11.8 0.1 3.2 3 1 0 3 3 3 0 Family of unknown function (DUF5588) TPR_20 PF14561.6 KUM55649.1 - 0.042 14.2 11.0 2.5 8.5 0.0 5.3 3 2 3 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 KUM55649.1 - 0.051 13.6 6.7 17 5.6 0.1 4.8 2 1 2 4 4 4 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 KUM55649.1 - 0.072 12.6 3.6 4.7 6.7 0.0 4.4 5 0 0 5 5 5 0 SHNi-TPR ChAPs PF09295.10 KUM55649.1 - 0.18 10.8 2.5 10 5.0 0.3 2.7 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) RPT PF13446.6 KUM55649.1 - 0.56 10.2 4.5 1.3 9.0 0.0 3.7 4 1 1 5 5 4 0 A repeated domain in UCH-protein GRP PF07172.11 KUM55649.1 - 0.72 10.6 10.8 1.7 9.3 10.8 1.7 1 0 0 1 1 1 0 Glycine rich protein family MFS_1 PF07690.16 KUM55650.1 - 9.8e-22 77.3 12.4 9.8e-22 77.3 12.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Toxin_18 PF08087.11 KUM55650.1 - 0.28 11.2 3.8 1.2 9.2 0.8 2.7 2 0 0 2 2 2 0 Conotoxin O-superfamily DUF3267 PF11667.8 KUM55650.1 - 8.4 6.7 10.8 0.7 10.2 0.3 3.1 2 1 1 3 3 3 0 Putative zincin peptidase Amidohydro_3 PF07969.11 KUM55651.1 - 1.1e-73 249.4 0.2 1.2e-73 249.2 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KUM55651.1 - 4.5e-10 39.4 0.0 1e-05 25.1 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.16 KUM55652.1 - 1.9e-22 79.7 28.9 1.9e-22 79.7 28.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily PufQ PF05398.11 KUM55652.1 - 0.14 12.3 0.9 0.96 9.6 0.3 2.6 2 0 0 2 2 2 0 PufQ cytochrome subunit Pkinase PF00069.25 KUM55653.1 - 1.7e-15 57.1 0.0 2.4e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM55653.1 - 2e-06 27.3 0.0 3.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AflR PF08493.10 KUM55654.1 - 9.4e-09 35.1 0.8 1.5e-08 34.4 0.8 1.4 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 KUM55654.1 - 2.3e-08 34.0 10.4 2.3e-08 34.0 10.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM55655.1 - 2.1e-08 33.5 0.2 1e-07 31.3 0.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.12 KUM55656.1 - 3.5e-21 75.1 6.7 5.8e-21 74.4 6.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM55656.1 - 1.3e-17 64.0 0.0 2.4e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KUM55656.1 - 4.4e-05 22.9 0.0 7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KUM55656.1 - 0.00087 18.7 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KUM55657.1 - 4.9e-14 52.0 1.7 1e-13 51.0 1.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM55657.1 - 1.4e-08 34.7 9.2 2.7e-08 33.8 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_teg_N PF04843.12 KUM55657.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region Pkinase PF00069.25 KUM55658.1 - 2.3e-15 56.7 0.0 9.8e-15 54.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM55658.1 - 4.6e-13 49.1 0.0 2.8e-12 46.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KUM55658.1 - 0.015 14.6 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KUM55658.1 - 0.017 15.0 0.1 0.03 14.3 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KUM55658.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase DLH PF01738.18 KUM55659.1 - 6.2e-17 61.9 0.1 7.4e-17 61.6 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family SNF2_N PF00176.23 KUM55661.1 - 1.5e-63 214.6 0.1 3.3e-63 213.5 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KUM55661.1 - 1.4e-23 83.4 0.7 3.9e-22 78.7 0.0 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KUM55661.1 - 2e-07 30.5 0.0 4.2e-06 26.1 0.0 2.4 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KUM55661.1 - 2.3e-07 31.0 0.0 7.1e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KUM55661.1 - 2.8e-06 26.7 0.6 5.2e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 KUM55661.1 - 0.0098 15.7 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Type_III_YscX PF09474.10 KUM55661.1 - 0.019 15.3 0.0 0.067 13.5 0.0 2.0 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) MobB PF03205.14 KUM55661.1 - 0.34 10.8 3.3 5.4 6.9 0.1 3.6 4 1 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B Acetyltransf_3 PF13302.7 KUM55662.1 - 3.9e-11 43.8 0.0 5.2e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM55662.1 - 0.031 14.5 0.0 0.04 14.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family NMT1 PF09084.11 KUM55665.1 - 6.4e-79 264.9 0.0 8.3e-79 264.5 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KUM55665.1 - 0.00012 21.9 0.4 0.13 12.0 0.0 3.2 3 1 0 3 3 3 2 NMT1-like family Me-amine-dh_L PF02975.14 KUM55666.1 - 0.13 12.7 0.0 0.17 12.4 0.0 1.1 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain Glycogen_syn PF05693.13 KUM55667.1 - 0 1148.8 0.0 0 1148.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_trans_1_4 PF13692.6 KUM55667.1 - 3.5e-05 24.3 0.0 0.016 15.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KUM55667.1 - 4e-05 23.7 0.6 0.00011 22.2 0.6 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 KUM55667.1 - 6.6e-05 22.7 0.0 0.00016 21.4 0.0 1.7 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KUM55667.1 - 0.00012 21.6 0.0 0.0023 17.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KUM55667.1 - 0.00069 20.1 0.1 0.0019 18.6 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain F1F0-ATPsyn_F PF10791.9 KUM55668.1 - 5.2e-42 142.2 0.1 5.9e-42 142.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 KUM55668.1 - 0.0014 18.9 0.0 0.002 18.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.12 KUM55669.1 - 3.1e-36 123.5 3.7 4.1e-36 123.1 3.7 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region DDE_3 PF13358.6 KUM55671.1 - 0.00076 19.2 0.0 0.00076 19.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Sugar_tr PF00083.24 KUM55672.1 - 1.8e-05 23.8 0.5 2.1e-05 23.6 0.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Lipase_3 PF01764.25 KUM55673.1 - 1.1e-15 57.8 0.0 1.7e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KUM55673.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ank_2 PF12796.7 KUM55675.1 - 2.8e-53 178.4 30.1 2e-16 60.4 1.8 5.1 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM55675.1 - 1.7e-31 108.2 9.5 7.3e-06 26.4 0.2 7.8 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM55675.1 - 8.1e-27 92.9 12.8 1.8e-06 28.1 0.4 6.8 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KUM55675.1 - 2.1e-26 91.1 24.8 0.0026 18.1 0.2 9.3 9 0 0 9 9 8 6 Ankyrin repeat Ank_3 PF13606.6 KUM55675.1 - 2.1e-14 52.2 8.6 2.5 8.9 0.0 9.0 9 0 0 9 9 8 4 Ankyrin repeat PNP_UDP_1 PF01048.20 KUM55675.1 - 1.4e-13 50.6 0.2 1.2e-12 47.6 0.2 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KUM55675.1 - 3e-11 43.5 0.2 5.7e-11 42.6 0.2 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KUM55675.1 - 0.0002 21.6 0.1 0.00076 19.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KUM55675.1 - 0.00024 21.5 0.2 0.0011 19.3 0.2 2.2 1 0 0 1 1 1 1 AAA ATPase domain DUF2521 PF10730.9 KUM55675.1 - 0.0033 17.5 0.5 52 3.8 0.0 4.7 2 2 2 4 4 4 0 Protein of unknown function (DUF2521) NB-ARC PF00931.22 KUM55675.1 - 0.054 12.7 0.0 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain HEM4 PF02602.15 KUM55675.1 - 0.19 11.0 0.3 4.6 6.5 0.0 3.1 1 1 2 3 3 3 0 Uroporphyrinogen-III synthase HemD Ribonuc_L-PSP PF01042.21 KUM55676.1 - 3.5e-21 75.5 0.0 4.6e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans PF04082.18 KUM55677.1 - 6.1e-11 41.9 0.1 2.4e-10 39.9 0.0 2.1 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM55677.1 - 7.4e-08 32.4 5.5 1.6e-07 31.4 5.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N PF02798.20 KUM55678.1 - 5.3e-14 52.3 0.0 1.2e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KUM55678.1 - 2.8e-12 46.7 0.0 4.5e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KUM55678.1 - 3.1e-12 46.7 0.0 5.7e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KUM55678.1 - 3.6e-12 46.3 0.0 6.2e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KUM55678.1 - 5.4e-09 36.2 0.0 1.6e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KUM55678.1 - 0.0028 17.7 0.0 0.0066 16.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KUM55678.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein DUF3791 PF12668.7 KUM55678.1 - 0.13 12.3 0.0 0.55 10.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) MFS_1 PF07690.16 KUM55679.1 - 4e-24 85.2 47.7 4e-24 85.2 47.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1129 PF06570.11 KUM55679.1 - 0.0068 15.9 0.3 0.0068 15.9 0.3 3.0 2 2 1 3 3 3 1 Protein of unknown function (DUF1129) DUF4179 PF13786.6 KUM55679.1 - 9.7 6.7 6.0 4.2 7.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Ribosomal_L28e PF01778.17 KUM55680.1 - 5.5e-25 88.3 3.2 1.6e-24 86.8 3.2 1.7 1 1 0 1 1 1 1 Ribosomal L28e protein family Stm1_N PF09598.10 KUM55680.1 - 1.4 9.8 7.8 1.5 9.7 0.3 2.4 2 0 0 2 2 2 0 Stm1 Ldh_1_N PF00056.23 KUM55681.1 - 0.23 11.6 0.8 0.22 11.6 0.8 1.0 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain RRM_1 PF00076.22 KUM55682.1 - 1.4e-33 114.5 0.0 1.7e-15 56.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KUM55682.1 - 0.00029 20.4 0.1 0.19 11.3 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KUM55682.1 - 0.005 16.5 0.1 0.17 11.6 0.1 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain RRM_7 PF16367.5 KUM55682.1 - 0.0056 16.8 0.0 0.021 14.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif Cas_Cas2CT1978 PF09707.10 KUM55682.1 - 0.016 15.3 0.0 5.1 7.2 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) RRM_occluded PF16842.5 KUM55682.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KUM55682.1 - 0.039 14.0 0.1 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 DUF2015 PF09435.10 KUM55683.1 - 2.4e-46 156.2 0.0 2.9e-46 155.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Mito_carr PF00153.27 KUM55684.1 - 5.2e-56 186.6 2.7 4.1e-20 71.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tom7 PF08038.12 KUM55685.1 - 1.1e-20 73.0 0.3 1.6e-20 72.5 0.3 1.2 1 0 0 1 1 1 1 TOM7 family E1-E2_ATPase PF00122.20 KUM55687.1 - 5e-51 172.8 1.1 5e-51 172.8 1.1 3.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KUM55687.1 - 3.7e-46 157.1 6.1 3.7e-46 157.1 6.1 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KUM55687.1 - 1.5e-21 77.7 1.0 6.3e-21 75.6 1.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KUM55687.1 - 6.7e-19 67.3 0.0 2.2e-18 65.7 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KUM55687.1 - 7.9e-18 64.3 0.0 1.5e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KUM55687.1 - 4.3e-07 29.9 3.0 1.6e-05 24.8 2.4 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KUM55687.1 - 6.7e-07 29.9 0.0 2.9e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2222 PF09984.9 KUM55687.1 - 0.09 12.7 0.2 18 5.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) adh_short_C2 PF13561.6 KUM55688.1 - 3e-44 151.3 0.6 3.7e-44 151.0 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM55688.1 - 1.2e-40 139.1 0.5 1.5e-40 138.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM55688.1 - 2.6e-10 40.5 0.2 4e-10 39.9 0.2 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KUM55688.1 - 0.046 13.1 0.0 0.72 9.2 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 KUM55689.1 - 5.3e-32 111.1 30.1 5.3e-32 111.1 30.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily GFO_IDH_MocA_C PF02894.17 KUM55690.1 - 7.5e-18 64.6 0.2 1.8e-17 63.4 0.2 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 KUM55690.1 - 2e-17 64.1 0.0 3.5e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Fungal_trans PF04082.18 KUM55691.1 - 8.1e-15 54.6 1.7 1.6e-14 53.6 1.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2415 PF10313.9 KUM55693.1 - 2.3e-15 56.2 0.1 8e-15 54.5 0.1 1.9 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 KUM55693.1 - 0.16 12.3 0.0 28 5.1 0.0 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain MFS_1 PF07690.16 KUM55694.1 - 6e-21 74.7 25.6 6.5e-21 74.6 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Beta-lactamase PF00144.24 KUM55695.1 - 1e-09 38.1 0.1 1.3e-09 37.8 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KUM55696.1 - 1.7e-11 44.5 0.0 2.3e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) COesterase PF00135.28 KUM55698.1 - 1.6e-73 248.3 0.0 2.1e-73 248.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KUM55698.1 - 1.7e-07 31.3 0.2 1.2e-06 28.5 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KUM55698.1 - 0.18 10.7 0.0 1.1 8.0 0.0 1.9 2 0 0 2 2 2 0 Steryl acetyl hydrolase Syntaxin-18_N PF10496.9 KUM55700.1 - 5.7e-12 45.7 1.2 3e-11 43.4 0.1 2.5 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KUM55700.1 - 0.00019 21.3 0.1 0.00061 19.7 0.0 1.9 2 0 0 2 2 2 1 SNARE domain BLOC1_2 PF10046.9 KUM55700.1 - 0.46 10.8 6.0 0.21 11.9 1.4 2.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 KUM55700.1 - 0.71 8.9 6.2 0.1 11.7 1.3 1.9 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 KUM55700.1 - 0.85 8.8 2.5 1.6 7.9 0.5 2.0 2 0 0 2 2 2 0 TMPIT-like protein CENP-H PF05837.12 KUM55700.1 - 0.88 10.0 5.5 0.55 10.7 0.6 2.7 2 1 0 2 2 2 0 Centromere protein H (CENP-H) DUF16 PF01519.16 KUM55700.1 - 1.5 9.4 4.8 2 9.0 1.6 2.5 3 0 0 3 3 3 0 Protein of unknown function DUF16 AATF-Che1 PF13339.6 KUM55700.1 - 1.8 9.3 8.3 8.2 7.1 1.6 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Syntaxin-6_N PF09177.11 KUM55700.1 - 3.5 8.3 6.8 1.4 9.6 1.7 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal PhzC-PhzF PF02567.16 KUM55701.1 - 1.6e-11 44.2 0.0 2e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein TPR_1 PF00515.28 KUM55702.1 - 4e-12 45.4 7.6 4.1e-06 26.4 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KUM55702.1 - 1.2e-11 43.8 4.7 0.00079 19.4 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KUM55702.1 - 1.8e-08 34.6 0.2 3.1e-05 24.2 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KUM55702.1 - 4.3e-08 32.8 0.3 0.00016 21.7 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KUM55702.1 - 1.8e-05 24.4 0.9 0.00084 19.2 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat PB1 PF00564.24 KUM55702.1 - 3.1e-05 23.8 0.1 5.7e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_9 PF13371.6 KUM55702.1 - 0.00018 21.6 0.1 0.18 12.0 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KUM55702.1 - 0.00024 20.7 1.3 0.0023 17.6 0.1 2.9 2 1 1 3 3 3 1 TPR repeat TPR_6 PF13174.6 KUM55702.1 - 0.00039 20.9 0.3 13 6.7 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KUM55702.1 - 0.0004 21.0 0.3 0.076 13.7 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KUM55702.1 - 1.9 8.5 4.6 3.1 7.8 0.0 3.4 4 1 1 5 5 5 0 Tetratricopeptide repeat LisH PF08513.11 KUM55703.1 - 1.4e-05 24.9 1.9 4.5e-05 23.3 0.3 2.2 2 0 0 2 2 2 1 LisH Ferric_reduct PF01794.19 KUM55705.1 - 1.4e-24 86.6 8.7 1.4e-24 86.6 8.7 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KUM55705.1 - 7.9e-17 61.8 0.0 1.1e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KUM55705.1 - 2.3e-07 30.8 0.0 5.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KUM55705.1 - 1.1e-06 29.2 0.0 2.8e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain CRAL_TRIO PF00650.20 KUM55706.1 - 3e-44 150.5 0.0 5e-44 149.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KUM55706.1 - 3.2e-08 33.8 0.0 5.8e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KUM55706.1 - 1.2e-07 31.8 0.0 3.3e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF4007 PF13182.6 KUM55706.1 - 0.36 9.9 1.6 0.36 9.9 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4007) Ctr PF04145.15 KUM55707.1 - 4.6e-34 118.2 3.3 6.8e-34 117.6 3.3 1.2 1 0 0 1 1 1 1 Ctr copper transporter family UPF0016 PF01169.19 KUM55707.1 - 0.016 15.5 0.2 0.18 12.1 0.1 2.2 2 1 0 2 2 2 0 Uncharacterized protein family UPF0016 SelR PF01641.18 KUM55709.1 - 2.2e-44 150.4 1.1 2.8e-44 150.1 1.1 1.1 1 0 0 1 1 1 1 SelR domain ArfGap PF01412.18 KUM55710.1 - 7.1e-40 135.7 0.5 1e-39 135.2 0.5 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Aa_trans PF01490.18 KUM55711.1 - 1.9e-24 86.1 33.3 2.5e-24 85.8 33.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein gpUL132 PF11359.8 KUM55711.1 - 0.15 11.6 0.6 0.38 10.3 0.6 1.7 1 0 0 1 1 1 0 Glycoprotein UL132 Neurensin PF14927.6 KUM55713.1 - 0.14 11.9 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Neurensin GCV_T PF01571.21 KUM55714.1 - 7.7e-79 264.7 0.0 9.9e-79 264.3 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KUM55714.1 - 2.2e-16 59.6 0.2 4.9e-16 58.4 0.2 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain LVIVD PF08309.11 KUM55714.1 - 0.0025 17.1 0.0 0.006 15.9 0.0 1.6 1 0 0 1 1 1 1 LVIVD repeat Glyco_hydro_92 PF07971.12 KUM55715.1 - 7.9e-57 193.2 0.0 9.5e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 adh_short_C2 PF13561.6 KUM55718.1 - 3.9e-56 190.2 0.6 4.9e-56 189.9 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM55718.1 - 1.9e-40 138.4 0.1 2.4e-40 138.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM55718.1 - 2.9e-07 30.6 0.1 5.9e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM55718.1 - 0.00024 20.7 0.0 0.00034 20.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM55718.1 - 0.044 13.2 0.0 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KUM55718.1 - 0.15 11.9 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AATase PF07247.12 KUM55720.1 - 3.1e-10 39.2 0.0 1.2e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 Alcohol acetyltransferase Oxidored_FMN PF00724.20 KUM55721.1 - 7.5e-95 318.1 0.0 8.6e-95 317.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RFX_DNA_binding PF02257.15 KUM55722.1 - 2e-27 95.6 0.1 4e-27 94.6 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Sulfatase PF00884.23 KUM55723.1 - 1.1e-21 77.6 0.5 2.2e-21 76.6 0.5 1.6 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KUM55723.1 - 0.00065 19.4 1.1 0.0017 18.0 1.1 1.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Fungal_trans PF04082.18 KUM55725.1 - 3.6e-06 26.2 0.2 5.5e-06 25.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_71 PF03659.14 KUM55726.1 - 8.4e-36 123.6 11.4 4.3e-21 75.2 0.7 3.0 2 1 1 3 3 3 3 Glycosyl hydrolase family 71 Peptidase_S7 PF00949.21 KUM55727.1 - 0.0065 16.3 0.1 0.064 13.1 0.1 2.4 2 0 0 2 2 2 1 Peptidase S7, Flavivirus NS3 serine protease Trypsin PF00089.26 KUM55727.1 - 0.061 13.1 0.0 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 Trypsin Peptidase_S64 PF08192.11 KUM55727.1 - 0.064 11.8 0.0 0.17 10.3 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S64 Ku_PK_bind PF08785.11 KUM55729.1 - 7e-38 129.4 0.0 1.1e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 KUM55729.1 - 3.1e-18 66.2 0.1 7.1e-18 65.0 0.1 1.6 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 KUM55729.1 - 0.83 10.4 3.2 0.85 10.4 1.0 2.2 2 1 1 3 3 3 0 Ku70/Ku80 C-terminal arm Ku PF02735.16 KUM55730.1 - 3.1e-09 36.8 0.0 5.6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KUM55730.1 - 1.9e-06 27.8 0.0 2.4e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KUM55730.1 - 7.6e-05 23.0 1.2 0.00016 22.0 0.6 1.7 1 1 1 2 2 2 1 von Willebrand factor type A domain Sugar_tr PF00083.24 KUM55731.1 - 8.2e-89 298.5 19.6 1e-88 298.2 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM55731.1 - 1.4e-12 47.2 36.4 5.9e-12 45.2 25.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1700 PF08006.11 KUM55731.1 - 0.38 10.3 2.9 4.5 6.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) DUF2663 PF10864.8 KUM55731.1 - 0.46 10.9 1.6 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) DUF4149 PF13664.6 KUM55732.1 - 3.4e-28 97.9 3.8 9.4e-28 96.5 2.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 KUM55732.1 - 0.0056 17.0 0.4 0.0088 16.4 0.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) RRM_1 PF00076.22 KUM55734.1 - 6e-46 154.1 0.0 7.3e-17 61.0 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KUM55734.1 - 7.1e-06 25.9 0.1 0.0015 18.5 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KUM55734.1 - 9.4e-05 22.2 0.0 0.055 13.3 0.0 2.9 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KUM55734.1 - 0.00012 22.0 0.0 0.0012 18.9 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 KUM55734.1 - 0.00058 19.9 0.1 0.049 13.7 0.0 2.8 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 KUM55734.1 - 0.0087 15.7 0.0 0.065 12.8 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KUM55734.1 - 0.097 12.9 0.1 13 6.0 0.0 3.4 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter UPF0154 PF03672.13 KUM55734.1 - 0.2 11.7 1.6 0.42 10.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Dimer_Tnp_hAT PF05699.14 KUM55737.1 - 1.5e-12 47.1 0.0 4.3e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 KUM55737.1 - 2.1e-05 24.4 0.0 6.9e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) Ank_2 PF12796.7 KUM55739.1 - 5.5e-44 148.7 0.1 3.8e-15 56.2 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM55739.1 - 1.9e-37 127.2 3.0 1.2e-07 32.1 0.0 6.9 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM55739.1 - 3.9e-37 122.0 0.1 0.00055 20.2 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KUM55739.1 - 1e-30 105.4 2.2 4.8e-08 33.1 0.0 6.5 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KUM55739.1 - 9.3e-30 101.8 0.7 0.00024 21.4 0.0 7.6 7 0 0 7 7 7 7 Ankyrin repeat F-box PF00646.33 KUM55739.1 - 0.054 13.4 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 F-box domain DUF3799 PF12684.7 KUM55739.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) MMgT PF10270.9 KUM55741.1 - 1.4e-34 118.4 0.0 1.6e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter Ank_5 PF13857.6 KUM55742.1 - 2.7e-05 24.4 0.0 0.27 11.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KUM55742.1 - 5.7e-05 23.6 0.0 0.003 18.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KUM55742.1 - 8.9e-05 23.0 0.0 0.0008 19.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KUM55742.1 - 0.00018 21.7 0.0 0.26 11.9 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat CbtA PF09490.10 KUM55743.1 - 0.0014 18.4 0.2 0.002 17.9 0.2 1.2 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) EphA2_TM PF14575.6 KUM55743.1 - 0.011 16.6 0.1 0.026 15.4 0.1 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 KUM55743.1 - 0.015 15.2 0.2 0.017 15.0 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Mucin15 PF15672.5 KUM55743.1 - 0.023 14.2 0.1 0.044 13.3 0.1 1.5 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Gly-zipper_YMGG PF13441.6 KUM55743.1 - 0.032 14.0 3.7 0.06 13.1 3.7 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Amnionless PF14828.6 KUM55743.1 - 0.033 13.0 0.0 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF2755 PF10954.8 KUM55743.1 - 0.038 13.9 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) CD99L2 PF12301.8 KUM55743.1 - 0.04 14.2 2.2 0.046 14.0 1.3 1.5 1 1 0 1 1 1 0 CD99 antigen like protein 2 Rick_17kDa_Anti PF05433.15 KUM55743.1 - 0.05 13.5 5.2 0.05 13.5 5.2 1.5 1 1 1 2 2 2 0 Glycine zipper 2TM domain Lipoprotein_2 PF00921.17 KUM55743.1 - 0.071 12.6 3.1 2.6 7.5 0.4 2.0 2 0 0 2 2 2 0 Borrelia lipoprotein Gly-zipper_Omp PF13488.6 KUM55743.1 - 0.076 13.0 6.0 0.21 11.6 6.0 1.7 1 1 0 1 1 1 0 Glycine zipper Glt_symporter PF03616.14 KUM55743.1 - 0.14 10.8 0.1 0.17 10.5 0.1 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Podoplanin PF05808.11 KUM55743.1 - 1.5 8.9 5.4 3.7 7.6 5.4 1.7 1 1 0 1 1 1 0 Podoplanin Gram_pos_anchor PF00746.21 KUM55743.1 - 4.2 7.4 5.1 12 5.9 5.1 1.8 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Peptidase_S41 PF03572.18 KUM55744.1 - 8.8e-08 31.9 0.0 2.3e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 Glyco_hydro_72 PF03198.14 KUM55745.1 - 5.5e-99 331.4 0.0 1e-98 330.5 0.1 1.3 2 0 0 2 2 2 1 Glucanosyltransferase DUF5353 PF17304.2 KUM55745.1 - 1.4 8.8 4.0 9.1 6.1 0.0 3.3 3 1 0 3 3 3 0 Family of unknown function (DUF5353) Pkinase PF00069.25 KUM55746.1 - 3.6e-09 36.4 0.0 8.9e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM55746.1 - 3e-06 26.7 0.0 5.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM55746.1 - 0.073 12.4 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 Kinase-like MFS_1 PF07690.16 KUM55749.1 - 2.8e-47 161.4 31.1 2.8e-47 161.4 31.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM55749.1 - 4.1e-09 35.8 12.0 4.1e-09 35.8 12.0 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 KUM55749.1 - 4e-05 23.1 3.1 4e-05 23.1 3.1 2.8 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KUM55749.1 - 0.27 9.5 15.3 0.63 8.2 0.2 3.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Trypan_PARP PF05887.11 KUM55750.1 - 0.02 14.9 30.1 0.02 14.9 30.1 6.7 1 1 2 3 3 3 0 Procyclic acidic repetitive protein (PARP) TPMT PF05724.11 KUM55751.1 - 0.00014 21.6 0.0 0.00014 21.6 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) TPMT PF05724.11 KUM55752.1 - 1.7e-13 50.7 0.1 7.5e-13 48.6 0.1 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 KUM55752.1 - 8.1e-05 23.2 0.0 0.00011 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM55752.1 - 0.001 19.7 0.0 0.0018 19.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM55752.1 - 0.0032 17.3 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 KUM55752.1 - 0.066 12.4 0.0 0.09 11.9 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein AdoMet_MTase PF07757.13 KUM55752.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase TehB PF03848.14 KUM55752.1 - 0.18 11.2 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Complex1_49kDa PF00346.19 KUM55753.1 - 1.6e-123 411.2 0.0 2.2e-123 410.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KUM55753.1 - 0.01 14.7 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 0 Nickel-dependent hydrogenase RNA_pol_A_bac PF01000.26 KUM55754.1 - 2.6e-28 98.7 0.0 5e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KUM55754.1 - 4e-19 67.8 0.0 5.6e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain E2_bind PF08825.10 KUM55756.1 - 4.9e-30 103.5 0.0 7.3e-30 103.0 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain ThiF PF00899.21 KUM55756.1 - 1.4e-15 57.3 0.1 1.9e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 KUM55756.1 - 0.017 15.0 3.0 0.59 10.0 0.1 2.2 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site Ecm33 PF12454.8 KUM55756.1 - 0.047 13.8 0.3 0.086 13.0 0.3 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein E1_UFD PF09358.10 KUM55756.1 - 0.1 13.3 0.0 0.22 12.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin fold domain ABC2_membrane PF01061.24 KUM55759.1 - 2.1e-28 99.2 17.6 2.1e-28 99.2 17.6 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KUM55759.1 - 0.0011 18.1 11.0 0.0011 18.1 11.0 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein PDR_CDR PF06422.12 KUM55759.1 - 7 6.6 8.8 0.2 11.6 1.8 2.1 2 0 0 2 2 2 0 CDR ABC transporter PMT PF02366.18 KUM55760.1 - 1.7e-81 273.4 18.0 1.7e-81 273.4 18.0 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KUM55760.1 - 8.3e-67 224.6 10.1 8.3e-67 224.6 10.1 2.1 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KUM55760.1 - 1.6e-44 152.0 0.0 3.3e-44 151.0 0.0 1.5 1 0 0 1 1 1 1 MIR domain B12D PF06522.11 KUM55761.1 - 0.072 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit RHH_5 PF07878.11 KUM55761.1 - 0.12 12.2 0.1 0.46 10.4 0.0 1.8 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 DHHC PF01529.20 KUM55762.1 - 2.6e-34 118.2 7.8 2.6e-34 118.2 7.8 1.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.17 KUM55762.1 - 0.66 9.7 7.7 0.17 11.6 0.5 2.1 2 0 0 2 2 2 0 Yip1 domain Surp PF01805.20 KUM55764.1 - 7.1e-34 115.6 6.2 2.4e-16 59.4 0.7 2.4 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.8 KUM55764.1 - 1.6e-30 106.7 3.4 2.2e-30 106.1 3.4 1.2 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Tfb4 PF03850.14 KUM55764.1 - 0.22 11.0 0.5 0.31 10.5 0.5 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 Hemopexin PF00045.19 KUM55765.1 - 1.2e-13 50.7 3.2 0.0079 16.1 0.0 4.6 4 1 0 4 4 4 4 Hemopexin NUDIX PF00293.28 KUM55766.1 - 2.8e-08 33.9 0.0 3.3e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DBC1 PF14443.6 KUM55766.1 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 DBC1 ABC_tran PF00005.27 KUM55767.1 - 5.9e-21 75.4 0.0 1.5e-20 74.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KUM55767.1 - 4.3e-05 23.5 0.1 0.00019 21.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KUM55767.1 - 6.2e-05 22.7 0.1 0.00016 21.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KUM55767.1 - 0.00016 21.2 0.1 0.004 16.6 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KUM55767.1 - 0.00033 21.2 0.1 0.00056 20.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KUM55767.1 - 0.00053 19.8 0.0 0.00087 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KUM55767.1 - 0.0028 17.6 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase cobW PF02492.19 KUM55767.1 - 0.0073 15.9 0.4 0.013 15.1 0.4 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KUM55767.1 - 0.0074 16.6 0.1 0.025 14.8 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KUM55767.1 - 0.024 14.8 0.2 0.045 13.9 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KUM55767.1 - 0.026 14.9 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KUM55767.1 - 0.031 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KUM55767.1 - 0.038 14.1 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 KUM55767.1 - 0.042 13.9 0.1 0.073 13.1 0.1 1.4 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.6 KUM55767.1 - 0.043 14.2 0.0 0.078 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KUM55767.1 - 0.056 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KUM55767.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 KUM55767.1 - 0.063 12.1 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein ABC_ATPase PF09818.9 KUM55767.1 - 0.12 11.2 0.6 0.73 8.6 0.1 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_13 PF13166.6 KUM55767.1 - 0.24 10.0 0.0 0.39 9.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhaG_MnhG_YufB PF03334.14 KUM55767.1 - 4.4 7.6 7.8 3 8.1 0.6 2.9 2 0 0 2 2 2 0 Na+/H+ antiporter subunit Zn_clus PF00172.18 KUM55769.1 - 0.032 14.3 4.2 0.079 13.1 4.2 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.7 KUM55770.1 - 1.4e-153 499.9 43.6 1.1e-17 64.4 0.2 12.7 2 1 12 15 15 14 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM55770.1 - 3.8e-121 394.0 29.1 1.8e-10 41.1 0.0 16.4 3 3 15 19 19 19 19 Ankyrin repeats (many copies) Ank PF00023.30 KUM55770.1 - 9.9e-91 294.6 37.6 2e-06 28.0 0.1 22.3 22 0 0 22 22 22 21 Ankyrin repeat Ank_3 PF13606.6 KUM55770.1 - 4e-88 278.7 0.0 0.0015 18.8 0.0 22.9 23 0 0 23 23 23 20 Ankyrin repeat Helo_like_N PF17111.5 KUM55770.1 - 1.9e-78 262.7 2.4 1.9e-78 262.7 2.4 2.0 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Ank_5 PF13857.6 KUM55770.1 - 7.2e-66 217.4 12.5 2.1e-05 24.7 0.0 18.0 2 2 18 20 20 20 19 Ankyrin repeats (many copies) Amidinotransf PF02274.17 KUM55770.1 - 0.0095 15.1 17.5 49 2.9 0.2 9.4 3 2 3 7 7 7 0 Amidinotransferase DUF3710 PF12502.8 KUM55770.1 - 0.098 12.3 30.9 40 3.8 0.3 12.1 1 1 8 10 10 10 0 Protein of unknown function (DUF3710) ParD_antitoxin PF03693.14 KUM55770.1 - 0.11 12.9 6.1 0.88 10.0 0.0 5.8 6 0 0 6 6 4 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH HMMR_N PF15905.5 KUM55770.1 - 0.49 9.8 11.3 0.99 8.8 3.7 2.5 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Mic1 PF07035.12 KUM55770.1 - 0.56 9.9 12.0 52 3.5 0.0 8.4 6 5 5 12 12 12 0 Colon cancer-associated protein Mic1-like MICSWaP PF17018.5 KUM55770.1 - 1.3 8.6 4.9 4.4 6.8 4.9 1.9 1 0 0 1 1 1 0 Spore wall protein CCDC-167 PF15188.6 KUM55770.1 - 8.5 6.8 6.9 9.9 6.6 5.1 2.1 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 167 DUF1325 PF07039.11 KUM55771.1 - 8.4e-35 119.7 0.0 1.5e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.10 KUM55771.1 - 0.052 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Tudor_3 PF18115.1 KUM55771.1 - 0.076 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain PMI_typeI PF01238.21 KUM55772.1 - 9.4e-145 482.5 0.0 1.1e-144 482.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KUM55772.1 - 0.0017 18.0 0.1 0.016 14.9 0.1 2.1 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 KUM55772.1 - 0.011 15.6 0.0 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 AraC-like ligand binding domain Abhydrolase_3 PF07859.13 KUM55773.1 - 4.3e-13 49.6 0.1 7e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KUM55773.1 - 2.2e-12 46.5 0.0 2.8e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF3425 PF11905.8 KUM55774.1 - 2.6e-23 82.3 1.5 4.2e-23 81.7 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KUM55774.1 - 0.022 14.9 3.2 0.063 13.4 3.2 1.8 1 1 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KUM55774.1 - 0.16 12.1 4.3 1.9 8.6 4.3 2.2 1 1 0 1 1 1 0 Basic region leucine zipper GTP_cyclohydro2 PF00925.20 KUM55775.1 - 1.6e-58 196.9 0.0 2.1e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II SF1-HH PF16275.5 KUM55776.1 - 4.6e-43 146.1 1.5 4.6e-43 146.1 1.5 1.9 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KUM55776.1 - 6.6e-12 44.9 11.1 1.4e-05 25.0 0.8 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KUM55776.1 - 1.9e-07 30.8 0.1 3.6e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 KUM55776.1 - 1.1e-06 28.5 5.4 0.0014 18.5 2.9 2.7 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KUM55776.1 - 0.00091 19.0 6.3 0.32 10.9 0.5 2.9 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KUM55776.1 - 0.0015 18.2 5.0 0.44 10.3 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 KUM55776.1 - 0.015 15.1 0.5 0.015 15.1 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle GST_N PF02798.20 KUM55777.1 - 5.2e-15 55.5 0.0 1.1e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KUM55777.1 - 1.4e-14 54.3 0.0 2.6e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KUM55777.1 - 2.5e-12 46.9 0.0 5.4e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KUM55777.1 - 3.2e-09 36.9 0.0 6.1e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KUM55777.1 - 9.2e-09 35.4 0.0 1.7e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KUM55777.1 - 4.6e-07 29.8 0.1 1.1e-06 28.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain RTA1 PF04479.13 KUM55778.1 - 2.7e-49 167.6 6.8 3.3e-49 167.3 6.8 1.0 1 0 0 1 1 1 1 RTA1 like protein Tannase PF07519.11 KUM55779.1 - 2.2e-22 79.6 0.2 2.6e-22 79.4 0.2 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 KUM55779.1 - 0.0067 16.1 0.1 0.008 15.8 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_39 PF01229.17 KUM55779.1 - 0.26 9.9 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 Tannase PF07519.11 KUM55780.1 - 1.8e-20 73.3 0.2 2e-20 73.2 0.2 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase DUF4050 PF13259.6 KUM55781.1 - 2e-51 174.9 14.9 1.2e-50 172.4 14.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) AAA PF00004.29 KUM55782.1 - 1.3e-39 135.6 0.0 2.6e-37 128.2 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KUM55782.1 - 7.8e-09 35.2 0.1 2.1e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KUM55782.1 - 4.4e-05 23.9 0.2 0.001 19.5 0.2 3.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KUM55782.1 - 0.00012 21.8 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KUM55782.1 - 0.00022 20.5 0.1 0.0007 18.9 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 KUM55782.1 - 0.00024 21.4 0.7 0.021 15.1 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KUM55782.1 - 0.00069 19.8 0.0 0.0049 17.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KUM55782.1 - 0.0013 18.8 0.0 0.004 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 KUM55782.1 - 0.0016 18.8 0.1 0.13 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KUM55782.1 - 0.0076 16.0 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KUM55782.1 - 0.02 14.3 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KUM55782.1 - 0.021 15.1 0.1 0.048 13.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KUM55782.1 - 0.032 14.6 0.0 0.09 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase HTH_ABP1_N PF18107.1 KUM55782.1 - 0.042 13.6 0.1 0.18 11.5 0.1 2.1 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain AAA_14 PF13173.6 KUM55782.1 - 0.046 13.7 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KUM55782.1 - 0.063 13.8 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KUM55782.1 - 0.074 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KUM55782.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KUM55782.1 - 0.26 10.7 0.8 1.4 8.3 0.2 2.2 2 0 0 2 2 2 0 PhoH-like protein Sld5 PF05916.11 KUM55783.1 - 5.6e-13 49.3 0.0 8.6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein FliT PF05400.13 KUM55783.1 - 0.016 16.0 0.1 0.2 12.5 0.0 2.6 3 0 0 3 3 3 0 Flagellar protein FliT Sulfate_transp PF00916.20 KUM55785.1 - 3.1e-65 220.4 26.9 4.4e-65 219.9 26.9 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KUM55785.1 - 5.7e-11 42.1 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain Uma2 PF05685.12 KUM55786.1 - 0.0058 16.2 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease AP3D1 PF06375.11 KUM55789.1 - 0.99 9.6 18.3 0.97 9.6 18.3 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 OAD_gamma PF04277.13 KUM55789.1 - 1.9 9.1 7.6 2.2 8.9 7.6 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SR-25 PF10500.9 KUM55789.1 - 5.4 6.6 25.1 5.5 6.5 25.1 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-C2H2 PF00096.26 KUM55791.1 - 2.5e-08 33.9 17.1 0.00053 20.3 4.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KUM55791.1 - 4.6e-08 33.1 19.7 4e-05 23.8 3.3 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KUM55791.1 - 0.001 19.7 15.8 0.037 14.9 3.0 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 KUM55791.1 - 0.021 15.4 1.8 0.11 13.2 0.2 2.6 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KUM55791.1 - 0.07 13.2 0.9 6.5 6.9 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KUM55791.1 - 0.085 13.2 0.2 0.085 13.2 0.2 2.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KUM55791.1 - 2.8 7.8 14.2 2.4 8.0 0.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain DUF188 PF02639.14 KUM55792.1 - 0.38 10.4 2.9 0.52 10.0 2.9 1.1 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 Atrophin-1 PF03154.15 KUM55792.1 - 0.83 7.9 4.3 0.99 7.6 4.3 1.0 1 0 0 1 1 1 0 Atrophin-1 family RVT_1 PF00078.27 KUM55793.1 - 1.5e-32 112.9 0.0 3.1e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1987 PF09345.10 KUM55793.1 - 0.015 15.0 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) MFS_1 PF07690.16 KUM55794.1 - 3.2e-24 85.5 65.3 1.7e-20 73.3 43.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 KUM55794.1 - 0.012 14.3 17.4 0.025 13.2 14.7 2.7 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like LOR PF04525.12 KUM55795.1 - 1.3e-05 24.9 0.0 4.8e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 LURP-one-related NUDIX PF00293.28 KUM55797.1 - 1.5e-17 63.8 0.1 2.2e-17 63.3 0.1 1.3 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KUM55797.1 - 0.0056 16.6 0.0 0.0066 16.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain adh_short PF00106.25 KUM55798.1 - 9e-31 106.9 0.0 1.2e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM55798.1 - 1.5e-21 77.1 0.0 2e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KUM55798.1 - 3.9e-06 26.5 0.0 7.5e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KUM55798.1 - 4e-06 26.9 0.1 5.5e-05 23.1 0.1 2.1 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 KUM55798.1 - 0.0033 17.7 0.0 0.0068 16.7 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.6 KUM55798.1 - 0.0062 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KUM55798.1 - 0.0077 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KUM55798.1 - 0.061 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase UPF0146 PF03686.13 KUM55798.1 - 0.078 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Polysacc_synt_2 PF02719.15 KUM55798.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Hemerythrin PF01814.23 KUM55799.1 - 7.8e-08 33.0 0.1 1.1e-07 32.5 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain p450 PF00067.22 KUM55800.1 - 7.3e-69 232.7 0.0 8.8e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADP_ribosyl_GH PF03747.14 KUM55802.1 - 2.1e-55 188.5 0.2 2.5e-55 188.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase NmrA PF05368.13 KUM55803.1 - 2.4e-12 46.9 0.0 3.2e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM55803.1 - 0.00066 19.6 0.0 0.0022 17.9 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Chorismate_bind PF00425.18 KUM55804.1 - 1.2e-91 306.9 0.0 1.6e-91 306.5 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KUM55804.1 - 3.2e-28 98.7 0.0 4.2e-25 88.6 0.0 2.8 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region Methyltransf_2 PF00891.18 KUM55805.1 - 5.2e-16 58.6 0.0 7.8e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KUM55805.1 - 0.00015 22.4 0.0 0.00063 20.4 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 KUM55805.1 - 0.00062 19.4 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain A2M_recep PF07677.14 KUM55805.1 - 0.0022 18.6 0.1 0.64 10.8 0.0 2.8 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain Methyltransf_12 PF08242.12 KUM55805.1 - 0.0088 16.8 0.0 0.065 14.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Sec3-PIP2_bind PF15277.6 KUM55805.1 - 0.02 15.0 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH DUF938 PF06080.12 KUM55805.1 - 0.031 14.0 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_18 PF12847.7 KUM55805.1 - 0.052 13.5 0.0 5 7.1 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.6 KUM55805.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 KUM55805.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_23 PF13489.6 KUM55805.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KUM55805.1 - 0.16 11.3 0.0 0.4 10.0 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AA_permease PF00324.21 KUM55806.1 - 1.1e-134 449.7 49.2 1.3e-134 449.4 49.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM55806.1 - 9.7e-33 113.6 54.7 1.2e-32 113.3 54.7 1.1 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.28 KUM55808.1 - 8.3e-83 278.3 0.0 1e-82 278.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Tugs PF17840.1 KUM55808.1 - 0.044 14.0 0.0 0.096 12.9 0.0 1.5 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain GST_N_3 PF13417.6 KUM55809.1 - 4.4e-12 46.2 0.0 9e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KUM55809.1 - 2.2e-10 40.7 0.0 3.9e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KUM55809.1 - 0.00017 21.5 0.0 0.00037 20.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KUM55809.1 - 0.0072 16.6 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain EF-hand_4 PF12763.7 KUM55810.1 - 2.1e-36 124.0 0.0 2.3e-14 53.2 0.0 4.0 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KUM55810.1 - 4.9e-07 30.1 0.0 0.0011 19.3 0.1 4.0 3 1 1 4 4 4 1 EF-hand domain pair UBA PF00627.31 KUM55810.1 - 2.7e-06 27.2 0.0 6.1e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 KUM55810.1 - 4.6e-06 25.8 0.0 0.0019 17.6 0.0 4.5 5 0 0 5 5 5 1 EF hand GAS PF13851.6 KUM55810.1 - 0.00011 21.6 23.5 0.012 15.0 12.0 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding EF-hand_8 PF13833.6 KUM55810.1 - 0.00026 20.8 0.0 0.19 11.6 0.0 4.0 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 KUM55810.1 - 0.00038 20.2 0.6 1.4 9.1 0.0 5.2 5 0 0 5 5 5 1 EF-hand domain Spc7 PF08317.11 KUM55810.1 - 0.00081 18.4 28.2 0.025 13.5 13.7 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KUM55810.1 - 0.0027 17.7 30.2 0.059 13.4 18.4 2.5 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 KUM55810.1 - 0.0044 16.4 13.7 0.0044 16.4 13.7 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 KUM55810.1 - 0.033 14.4 22.6 0.26 11.5 4.1 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding EF-hand_5 PF13202.6 KUM55810.1 - 0.042 13.4 0.1 0.24 10.9 0.0 2.3 2 0 0 2 2 2 0 EF hand Macoilin PF09726.9 KUM55810.1 - 0.056 12.0 13.3 0.0033 16.1 7.5 1.8 2 0 0 2 2 2 0 Macoilin family DUF812 PF05667.11 KUM55810.1 - 0.2 10.5 23.4 0.32 9.8 21.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) COG2 PF06148.11 KUM55810.1 - 0.45 10.6 10.4 2.3 8.3 1.3 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3584 PF12128.8 KUM55810.1 - 0.59 7.6 24.5 0.82 7.1 24.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FPP PF05911.11 KUM55810.1 - 0.93 7.6 20.0 1.3 7.1 20.0 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil FUSC PF04632.12 KUM55810.1 - 2 6.9 8.7 3 6.2 8.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fib_alpha PF08702.10 KUM55810.1 - 2.1 8.5 18.5 0.7 10.1 11.0 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4686 PF15742.5 KUM55810.1 - 3.6 6.6 27.1 5.4 6.1 27.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) CENP-F_leu_zip PF10473.9 KUM55810.1 - 6.4 6.8 24.2 0.21 11.6 3.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 KUM55810.1 - 8.6 5.8 18.1 14 5.1 18.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PI3K_P85_iSH2 PF16454.5 KUM55810.1 - 9.1 5.9 17.9 27 4.3 17.8 1.7 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain GST_C_3 PF14497.6 KUM55811.1 - 4.8e-19 68.4 0.0 1e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KUM55811.1 - 1.9e-06 28.0 0.0 3e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KUM55811.1 - 9.3e-05 22.7 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KUM55811.1 - 0.0014 18.6 0.0 0.0036 17.3 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KUM55811.1 - 0.074 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain CFEM PF05730.11 KUM55812.1 - 0.0062 16.6 6.7 0.013 15.5 6.7 1.6 1 1 0 1 1 1 1 CFEM domain DUF1993 PF09351.10 KUM55813.1 - 6.4e-47 159.7 0.0 7.2e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) TMEMspv1-c74-12 PF11044.8 KUM55814.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF4748 PF15932.5 KUM55814.1 - 0.038 13.7 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) ZirS_C PF16583.5 KUM55814.1 - 0.039 13.5 0.4 0.039 13.5 0.4 1.6 2 0 0 2 2 2 0 Zinc-regulated secreted antivirulence protein C-terminal domain UCH PF00443.29 KUM55816.1 - 4.2e-59 200.1 0.0 6.1e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KUM55816.1 - 7.1e-10 39.4 0.0 5e-09 36.7 0.0 2.4 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 KUM55816.1 - 3.6e-09 36.7 0.1 0.12 11.9 0.0 3.6 4 0 0 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase HSDR_N_2 PF13588.6 KUM55817.1 - 0.16 12.0 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) CPBP PF02517.16 KUM55822.1 - 5.2e-15 55.6 7.0 5.2e-15 55.6 7.0 2.3 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease zf-Mss51 PF13824.6 KUM55823.1 - 5.1e-29 100.1 7.1 1.1e-28 99.1 7.1 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF3011 PF11218.8 KUM55823.1 - 0.01 15.8 0.1 0.018 15.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3011) zf-MYND PF01753.18 KUM55823.1 - 0.03 14.4 0.3 0.03 14.4 0.3 1.9 2 0 0 2 2 2 0 MYND finger zf-HIT PF04438.16 KUM55823.1 - 0.41 10.6 2.3 2 8.4 0.4 2.4 2 0 0 2 2 2 0 HIT zinc finger Oxysterol_BP PF01237.18 KUM55824.1 - 1.2e-134 448.8 0.4 2.1e-133 444.8 0.0 2.3 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.7 KUM55824.1 - 4.6e-15 56.0 0.0 6.5e-08 33.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KUM55824.1 - 1.9e-14 53.5 0.6 3.6e-09 36.7 0.2 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KUM55824.1 - 8.8e-12 44.9 0.1 0.0019 18.6 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.29 KUM55824.1 - 6.7e-11 42.6 0.4 1.5e-10 41.5 0.4 1.7 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 KUM55824.1 - 1e-08 34.7 0.1 0.0052 17.2 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KUM55824.1 - 4.7e-08 33.4 0.6 0.00011 22.7 0.1 4.3 3 1 2 5 5 5 2 Ankyrin repeats (many copies) PH_8 PF15409.6 KUM55824.1 - 8.7e-07 29.1 0.9 2.6e-06 27.6 0.9 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KUM55824.1 - 3.1e-05 24.3 2.3 3.1e-05 24.3 2.3 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Mei5 PF10376.9 KUM55824.1 - 0.12 12.2 6.3 0.16 11.8 4.3 2.2 1 1 1 2 2 2 0 Double-strand recombination repair protein XRN_M PF17846.1 KUM55824.1 - 0.13 11.2 0.8 0.26 10.2 0.8 1.4 1 0 0 1 1 1 0 Xrn1 helical domain EssA PF10661.9 KUM55824.1 - 6.7 6.6 7.2 36 4.2 0.1 3.4 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein EssA SGL PF08450.12 KUM55827.1 - 3.5e-24 85.8 0.9 9.1e-24 84.4 0.9 1.8 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KUM55827.1 - 2.1e-05 24.5 0.0 5.2e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 KUM55827.1 - 2.4e-05 24.4 0.1 0.00027 21.1 0.1 2.4 1 1 1 2 2 2 1 Arylesterase PD40 PF07676.12 KUM55827.1 - 0.03 14.2 0.2 0.15 12.1 0.5 2.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF667 PF05018.13 KUM55827.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF667) SKG6 PF08693.10 KUM55828.1 - 2.7e-05 23.5 0.2 4.6e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Yip1 PF04893.17 KUM55828.1 - 0.0023 17.7 0.1 0.0037 17.0 0.1 1.2 1 0 0 1 1 1 1 Yip1 domain Gram_pos_anchor PF00746.21 KUM55828.1 - 0.029 14.3 2.1 0.059 13.3 2.1 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF908 PF06012.12 KUM55828.1 - 0.078 12.4 4.7 0.091 12.2 4.7 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) Nitrate_red_gam PF02665.14 KUM55828.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit POTRA_3 PF17287.2 KUM55829.1 - 0.073 12.5 1.5 54 3.3 0.0 3.6 1 1 5 6 6 6 0 POTRA domain Clathrin PF00637.20 KUM55829.1 - 0.1 12.4 0.7 5.7 6.8 0.2 2.2 1 1 1 2 2 2 0 Region in Clathrin and VPS HSBP1 PF06825.12 KUM55829.1 - 0.72 9.8 3.7 30 4.6 0.3 3.4 1 1 0 2 2 2 0 Heat shock factor binding protein 1 DUF3328 PF11807.8 KUM55830.1 - 4.6e-37 127.9 0.1 5.6e-37 127.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) EPV_E5 PF08135.11 KUM55830.1 - 0.21 12.0 1.3 0.4 11.1 1.3 1.4 1 0 0 1 1 1 0 Major transforming protein E5 family DDE_3 PF13358.6 KUM55831.1 - 4.6e-32 110.8 0.0 3.4e-31 108.0 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_1 PF03184.19 KUM55831.1 - 1.9e-07 30.9 0.0 4.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 KUM55831.1 - 2.5e-06 27.0 0.2 2.8e-05 23.7 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn helix rve PF00665.26 KUM55831.1 - 2.7e-05 24.4 0.0 0.00022 21.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain HTH_32 PF13565.6 KUM55831.1 - 0.022 15.4 0.0 0.088 13.4 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain DUF4764 PF15961.5 KUM55831.1 - 0.069 11.8 0.0 0.089 11.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) DDE_Tnp_ISAZ013 PF07592.11 KUM55831.1 - 0.12 11.3 0.1 7.7 5.4 0.0 2.1 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain ERAP1_C PF11838.8 KUM55833.1 - 9e-88 294.8 1.1 1.2e-87 294.5 1.1 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KUM55833.1 - 1.4e-10 41.1 0.0 2.6e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1 PF01433.20 KUM55834.1 - 4.9e-50 170.1 7.2 7.4e-50 169.5 7.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KUM55834.1 - 2.1e-42 145.4 0.0 3.9e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Alpha_TIF PF02232.15 KUM55834.1 - 0.058 12.5 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) WD40 PF00400.32 KUM55836.1 - 0.00075 20.3 6.9 0.46 11.4 0.1 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Mito_carr PF00153.27 KUM55837.1 - 8e-53 176.3 2.4 4.4e-17 61.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AphA_like PF14557.6 KUM55837.1 - 0.0023 17.7 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Putative AphA-like transcriptional regulator Bacteriocin_IIc PF10439.9 KUM55837.1 - 0.015 15.4 2.2 0.45 10.7 0.2 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide TadE PF07811.12 KUM55837.1 - 0.074 13.3 0.4 2 8.8 0.1 2.6 2 0 0 2 2 2 0 TadE-like protein PrcB_C PF14343.6 KUM55837.1 - 0.093 12.9 0.0 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 PrcB C-terminal Abhydrolase_6 PF12697.7 KUM55839.1 - 5.1e-10 40.3 1.2 6.6e-10 40.0 1.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM55839.1 - 5.4e-10 39.3 0.4 2.4e-09 37.2 0.2 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM55839.1 - 1.5e-06 27.6 0.1 2.7e-06 26.8 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 adh_short PF00106.25 KUM55840.1 - 3.2e-26 92.0 0.0 3.9e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM55840.1 - 6.1e-22 78.3 0.0 7.8e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM55840.1 - 1.7e-07 31.3 0.0 2.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 KR domain FAS_N PF17828.1 KUM55841.1 - 8e-08 32.3 0.1 1.7e-07 31.3 0.1 1.6 1 1 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Epimerase PF01370.21 KUM55842.1 - 1.8e-15 57.1 0.1 9e-15 54.8 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KUM55842.1 - 4.1e-13 49.0 0.0 8.4e-13 48.0 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KUM55842.1 - 1.8e-09 37.5 0.0 4.6e-08 32.8 0.0 2.7 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KUM55842.1 - 2.1e-09 37.6 0.0 3.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KUM55842.1 - 1.9e-08 33.8 0.0 1.5e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KUM55842.1 - 2e-06 27.1 0.0 4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KUM55842.1 - 5.5e-05 22.8 0.0 9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KUM55842.1 - 0.00094 18.7 0.1 0.0023 17.4 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase 3HCDH_N PF02737.18 KUM55842.1 - 0.087 12.7 0.0 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KUM55842.1 - 0.12 11.5 0.0 0.67 9.0 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain JAB PF01398.21 KUM55843.1 - 3e-30 104.6 0.0 6.7e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KUM55843.1 - 4.2e-19 69.2 0.1 9.6e-19 68.1 0.1 1.6 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KUM55843.1 - 0.00028 20.6 0.0 0.00048 19.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain GBP_repeat PF02526.14 KUM55843.1 - 0.059 13.1 1.3 0.13 12.0 0.8 1.8 1 1 1 2 2 2 0 Glycophorin-binding protein RasGEF PF00617.19 KUM55844.1 - 8.6e-59 198.7 0.0 1.6e-58 197.8 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KUM55844.1 - 1.4e-30 105.7 0.5 2.8e-30 104.6 0.5 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KUM55844.1 - 8.9e-15 54.0 0.2 8.9e-15 54.0 0.2 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KUM55844.1 - 3.4e-13 49.2 0.1 9e-13 47.9 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KUM55844.1 - 2e-10 40.2 0.1 6.7e-10 38.5 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.26 KUM55844.1 - 0.0069 16.4 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 WW domain MAP65_ASE1 PF03999.12 KUM55845.1 - 7.8e-76 256.0 0.2 1.1e-75 255.5 0.2 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF885 PF05960.11 KUM55845.1 - 0.13 11.9 3.1 0.053 13.2 0.5 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) PEP-utilisers_N PF05524.13 KUM55845.1 - 1 9.5 3.6 15 5.8 0.2 3.0 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal LTXXQ PF07813.12 KUM55845.1 - 1.1 10.0 7.1 1.1 10.0 0.3 3.3 3 0 0 3 3 3 0 LTXXQ motif family protein Occludin_ELL PF07303.13 KUM55845.1 - 2.6 8.8 4.8 2.7 8.7 0.1 3.3 2 2 0 2 2 2 0 Occludin homology domain TACC_C PF05010.14 KUM55845.1 - 5.9 6.6 11.4 5 6.9 0.1 3.1 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal MFS_1 PF07690.16 KUM55847.1 - 3.8e-30 105.0 35.3 3.8e-30 105.0 35.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KUM55847.1 - 4.6e-06 26.2 3.9 4.6e-06 26.2 3.9 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Gly_acyl_tr_C PF08444.10 KUM55848.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region FAD_binding_3 PF01494.19 KUM55849.1 - 2.9e-20 72.8 0.0 3.6e-09 36.3 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KUM55849.1 - 0.0032 17.6 0.0 0.0079 16.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KUM55849.1 - 0.043 13.1 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM55849.1 - 0.052 12.8 0.0 0.078 12.2 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KUM55849.1 - 0.072 12.1 0.0 0.35 9.9 0.0 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein SE PF08491.10 KUM55849.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.14 KUM55849.1 - 0.2 10.3 0.0 0.35 9.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Aminotran_1_2 PF00155.21 KUM55850.1 - 1.8e-47 162.2 0.0 2.3e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ECH_1 PF00378.20 KUM55850.1 - 0.22 10.8 0.1 0.43 9.8 0.1 1.4 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase adh_short_C2 PF13561.6 KUM55851.1 - 6.9e-45 153.4 0.0 8.1e-45 153.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM55851.1 - 1.3e-43 148.8 0.0 1.8e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM55851.1 - 1.2e-06 28.5 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 KR domain OTU PF02338.19 KUM55852.1 - 3.5e-20 72.8 0.3 3.4e-19 69.6 0.3 2.2 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KUM55852.1 - 3.2e-06 26.8 0.0 0.00027 20.5 0.0 2.4 2 0 0 2 2 2 2 Peptidase C65 Otubain Cep57_MT_bd PF06657.13 KUM55852.1 - 0.17 12.3 5.1 0.44 11.0 5.1 1.8 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Ndc1_Nup PF09531.10 KUM55852.1 - 5.6 5.5 7.2 6.3 5.4 7.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ICL PF00463.21 KUM55853.1 - 3.1e-300 996.1 3.7 3.5e-300 996.0 3.7 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KUM55853.1 - 1.1e-11 44.6 0.1 2.5e-11 43.5 0.1 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF3197 PF11432.8 KUM55853.1 - 0.039 13.8 0.5 8.3 6.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3197) Trehalase PF01204.18 KUM55854.1 - 1.9e-192 640.6 0.1 2.3e-192 640.4 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KUM55854.1 - 4.9e-17 61.3 0.4 1e-16 60.4 0.4 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Ribosomal_S28e PF01200.18 KUM55859.1 - 4.2e-31 106.7 1.7 5.3e-31 106.4 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e HisG PF01634.18 KUM55860.1 - 6.6e-55 185.4 0.2 1.1e-54 184.7 0.2 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KUM55860.1 - 1.1e-28 99.1 0.2 2.5e-28 98.0 0.2 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 KUM55860.1 - 0.0003 20.8 0.1 0.00047 20.2 0.1 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Fungal_trans PF04082.18 KUM55863.1 - 2.6e-13 49.6 1.7 4.1e-13 49.0 1.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KUM55865.1 - 5.9e-32 111.0 30.6 5.9e-32 111.0 30.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2798 PF11391.8 KUM55865.1 - 0.026 14.6 1.2 0.026 14.6 1.2 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2798) DUF1129 PF06570.11 KUM55865.1 - 0.15 11.6 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) TMEM40 PF15817.5 KUM55865.1 - 3.6 7.4 5.9 0.57 9.9 0.6 2.3 2 1 1 3 3 3 0 Transmembrane protein 40 family WH2 PF02205.20 KUM55866.1 - 1.7e-11 43.5 0.6 2.3e-11 43.1 0.6 1.2 1 0 0 1 1 1 1 WH2 motif CAP_N PF01213.19 KUM55866.1 - 0.03 13.8 5.0 0.031 13.7 5.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DEC-1_N PF04625.13 KUM55866.1 - 7 5.6 6.6 6.3 5.7 6.6 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ABC_tran PF00005.27 KUM55867.1 - 2.1e-47 161.1 0.0 2.8e-27 95.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KUM55867.1 - 1.3e-43 149.6 42.3 1e-31 110.6 17.1 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KUM55867.1 - 4.4e-06 26.3 0.0 0.0087 15.5 0.9 3.1 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KUM55867.1 - 0.00013 22.0 0.2 0.17 12.0 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KUM55867.1 - 0.0016 18.1 0.1 0.47 10.2 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KUM55867.1 - 0.0035 17.8 0.7 3.8 7.9 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 KUM55867.1 - 0.0074 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 KUM55867.1 - 0.014 15.3 0.2 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 KUM55867.1 - 0.02 14.1 0.0 4.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_21 PF13304.6 KUM55867.1 - 0.024 14.4 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KUM55867.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KUM55867.1 - 0.1 12.2 0.9 1 8.9 0.1 2.6 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KUM55867.1 - 0.11 12.6 0.3 8.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 KUM55867.1 - 0.21 11.9 0.4 8.9 6.6 0.0 3.2 3 1 0 3 3 3 0 AAA domain MgsA_C PF12002.8 KUM55869.1 - 0.041 13.8 1.9 0.05 13.6 1.0 1.5 1 1 1 2 2 2 0 MgsA AAA+ ATPase C terminal TES PF08034.11 KUM55869.1 - 0.084 13.2 1.4 0.16 12.3 1.1 1.7 1 1 0 1 1 1 0 Trematode eggshell synthesis protein DUF3445 PF11927.8 KUM55870.1 - 2e-42 145.4 0.0 2.2e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF3445 PF11927.8 KUM55871.1 - 2.8e-15 56.6 0.0 3.4e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) 4HBT_3 PF13622.6 KUM55872.1 - 4.7e-77 259.6 0.0 5.5e-77 259.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KUM55872.1 - 3e-23 82.1 0.0 2.3e-12 46.9 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase DUF4277 PF14104.6 KUM55872.1 - 0.082 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4277) DUF4118 PF13493.6 KUM55873.1 - 0.00081 19.2 4.0 0.0018 18.0 4.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) Amidase PF01425.21 KUM55874.1 - 1e-35 123.6 0.6 8.2e-34 117.3 0.4 2.1 2 0 0 2 2 2 2 Amidase Zn_clus PF00172.18 KUM55875.1 - 0.00081 19.5 8.7 0.0015 18.6 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAHP_synth_1 PF00793.20 KUM55876.1 - 1.5e-98 329.1 0.0 1.8e-98 328.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.6 KUM55877.1 - 4.9e-19 67.9 0.2 4.9e-19 67.9 0.2 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c assembly ECM11 PF15463.6 KUM55877.1 - 0.0085 16.7 0.3 0.033 14.8 0.0 2.0 2 0 0 2 2 2 1 Extracellular mutant protein 11 DUF2458 PF10454.9 KUM55878.1 - 3.4e-65 218.9 0.2 4.5e-65 218.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) MFS_1 PF07690.16 KUM55879.1 - 4.6e-35 121.2 20.3 4.8e-34 117.8 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KUM55880.1 - 8.7e-09 34.8 1.3 1.7e-08 33.8 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain G_glu_transpept PF01019.21 KUM55881.1 - 3.2e-44 151.6 0.0 3.8e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase SET PF00856.28 KUM55883.1 - 1.2e-07 32.3 0.2 4.3e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 SET domain PHD PF00628.29 KUM55883.1 - 7.9e-06 25.7 9.2 1.5e-05 24.8 9.2 1.5 1 0 0 1 1 1 1 PHD-finger CDC73_C PF05179.14 KUM55884.1 - 2e-56 190.0 0.0 3.4e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal NADH-UOR_E PF16514.5 KUM55884.1 - 0.068 13.5 0.0 0.38 11.1 0.0 2.0 2 0 0 2 2 2 0 putative NADH-ubiquinone oxidoreductase chain E MFS_1 PF07690.16 KUM55885.1 - 3.1e-13 49.4 62.6 9.3e-09 34.7 22.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KUM55885.1 - 0.00014 21.0 3.0 0.00016 20.8 3.0 1.2 1 0 0 1 1 1 1 Nucleoside H+ symporter Sugar_tr PF00083.24 KUM55885.1 - 0.0006 18.8 9.5 0.0006 18.8 9.5 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KUM55885.1 - 0.084 11.1 10.2 0.016 13.5 3.7 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PAS_2 PF08446.11 KUM55885.1 - 0.2 12.3 0.0 0.31 11.7 0.0 1.3 1 0 0 1 1 1 0 PAS fold RGS PF00615.19 KUM55886.1 - 7.7e-35 119.7 0.1 1.7e-34 118.6 0.1 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KUM55886.1 - 3.5e-25 87.8 0.1 3.5e-19 68.6 0.0 3.5 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glyco_tran_WbsX PF14307.6 KUM55886.1 - 0.12 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase WbsX ELO PF01151.18 KUM55891.1 - 7.9e-84 281.1 7.4 9.6e-84 280.8 7.4 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Na_H_Exchanger PF00999.21 KUM55893.1 - 1.6e-39 135.8 20.9 2.7e-39 135.1 20.9 1.3 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Rbx_binding PF18113.1 KUM55894.1 - 0.12 12.2 0.2 0.25 11.1 0.2 1.6 1 1 0 1 1 1 0 Rubredoxin binding C-terminal domain AIM3 PF17096.5 KUM55895.1 - 0.0053 17.7 0.1 0.0053 17.7 0.1 6.0 5 3 0 5 5 5 1 Altered inheritance of mitochondria protein 3 Thioesterase PF00975.20 KUM55896.1 - 2.7e-05 24.4 1.5 3e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 KUM55896.1 - 8.4e-05 23.3 0.1 0.00014 22.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 KUM55896.1 - 0.0024 17.8 0.1 0.0055 16.7 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 KUM55896.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.13 KUM55896.1 - 0.014 15.2 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KUM55896.1 - 0.027 14.3 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) Hydrolase_4 PF12146.8 KUM55896.1 - 0.032 13.5 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 KUM55896.1 - 0.037 13.6 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) LIDHydrolase PF10230.9 KUM55896.1 - 0.053 13.1 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF676 PF05057.14 KUM55896.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 KUM55896.1 - 0.12 12.2 0.3 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase U79_P34 PF03064.16 KUM55896.1 - 1.5 8.1 13.6 2.7 7.3 13.6 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SMBP PF16785.5 KUM55896.1 - 1.8 8.8 0.0 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Small metal-binding protein NARP1 PF12569.8 KUM55896.1 - 2.4 7.0 13.8 3.6 6.4 13.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PHC2_SAM_assoc PF16616.5 KUM55896.1 - 3.6 8.4 15.3 3.1 8.7 13.9 1.6 1 1 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Uso1_p115_head PF04869.14 KUM55897.1 - 2e-107 358.9 0.0 7.2e-107 357.1 0.0 2.0 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KUM55897.1 - 3.4e-20 72.7 41.5 3.4e-20 72.7 41.5 5.8 1 1 3 5 5 4 2 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 KUM55897.1 - 7.4e-05 21.8 16.5 7.4e-05 21.8 16.5 4.0 1 1 3 4 4 4 1 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 KUM55897.1 - 0.0002 21.5 17.5 0.0002 21.5 17.5 6.1 1 1 4 5 5 4 3 Tropomyosin like Filament PF00038.21 KUM55897.1 - 0.00034 20.3 80.1 0.0019 17.8 17.3 5.2 1 1 3 4 4 4 1 Intermediate filament protein Taxilin PF09728.9 KUM55897.1 - 0.0012 18.1 48.7 0.0012 18.1 48.7 3.0 1 1 1 2 2 1 1 Myosin-like coiled-coil protein DUF724 PF05266.14 KUM55897.1 - 0.0014 18.5 9.3 0.0014 18.5 9.3 6.2 1 1 5 6 6 5 2 Protein of unknown function (DUF724) Jnk-SapK_ap_N PF09744.9 KUM55897.1 - 0.0017 18.6 10.1 0.0017 18.6 10.1 5.5 1 1 4 5 5 3 2 JNK_SAPK-associated protein-1 Pox_A_type_inc PF04508.12 KUM55897.1 - 0.0035 17.1 1.8 67 3.6 0.0 6.2 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat Golgin_A5 PF09787.9 KUM55897.1 - 0.0043 16.6 14.8 0.0043 16.6 14.8 4.3 1 1 2 4 4 4 2 Golgin subfamily A member 5 PLAC9 PF15205.6 KUM55897.1 - 0.063 13.7 0.6 0.56 10.6 0.1 2.7 2 0 0 2 2 2 0 Placenta-specific protein 9 KHA PF11834.8 KUM55897.1 - 0.12 12.5 1.0 6.9 6.8 0.1 3.2 1 1 1 2 2 2 0 KHA, dimerisation domain of potassium ion channel DUF3584 PF12128.8 KUM55897.1 - 0.22 9.0 87.0 0.032 11.8 49.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.19 KUM55897.1 - 0.23 9.2 93.7 0.06 11.2 31.7 2.8 1 1 1 2 2 2 0 Myosin tail FAM184 PF15665.5 KUM55897.1 - 0.59 9.9 85.9 0.047 13.5 10.2 3.7 1 1 3 4 4 4 0 Family with sequence similarity 184, A and B ATG16 PF08614.11 KUM55897.1 - 0.65 10.2 94.0 0.4 10.9 32.5 4.7 1 1 3 4 4 3 0 Autophagy protein 16 (ATG16) Surfac_D-trimer PF09006.11 KUM55897.1 - 0.69 9.8 10.1 29 4.7 0.1 5.2 6 0 0 6 6 6 0 Lung surfactant protein D coiled-coil trimerisation DUF1664 PF07889.12 KUM55897.1 - 2.1 8.4 51.9 0.2 11.7 6.9 6.0 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) Tropomyosin PF00261.20 KUM55897.1 - 2.6 7.4 88.6 0.043 13.2 14.9 5.7 1 1 3 4 4 3 0 Tropomyosin FUSC PF04632.12 KUM55897.1 - 2.6 6.5 38.9 0.097 11.2 15.6 3.6 1 1 1 2 2 2 0 Fusaric acid resistance protein family Cast PF10174.9 KUM55897.1 - 3.7 5.7 80.2 0.031 12.5 40.7 2.7 1 1 2 3 3 3 0 RIM-binding protein of the cytomatrix active zone XRN_M PF17846.1 KUM55898.1 - 1.4e-145 485.7 1.4 2.5e-144 481.5 0.0 2.7 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KUM55898.1 - 1.9e-99 332.0 1.8 5.6e-99 330.5 0.0 2.0 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 KUM55898.1 - 0.024 14.7 2.9 0.052 13.7 2.9 1.6 1 0 0 1 1 1 0 Zinc knuckle YTH PF04146.15 KUM55899.1 - 4.5e-61 205.6 0.0 7.1e-61 205.0 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 KUM55899.1 - 9.9e-07 28.5 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ArfGap PF01412.18 KUM55901.1 - 4.2e-34 117.1 0.1 4.2e-34 117.1 0.1 3.1 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KUM55901.1 - 1.1e-21 77.7 14.7 1.9e-21 76.9 14.7 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KUM55901.1 - 4.3e-12 46.5 0.3 1.4e-11 44.8 0.3 1.9 1 0 0 1 1 1 1 PH domain PMEI PF04043.15 KUM55901.1 - 0.047 14.0 0.5 0.17 12.2 0.5 2.0 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Fungal_trans PF04082.18 KUM55902.1 - 1.1e-19 70.5 0.2 2.9e-19 69.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM55902.1 - 1e-09 38.3 11.3 1e-09 38.3 11.3 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAD PF02109.16 KUM55903.1 - 4.3e-46 155.7 0.0 5.8e-46 155.3 0.0 1.2 1 0 0 1 1 1 1 DAD family MGC-24 PF05283.11 KUM55903.1 - 0.18 12.3 0.6 0.36 11.3 0.6 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin HA2 PF04408.23 KUM55904.1 - 7.9e-20 71.2 1.6 1.8e-19 70.0 0.0 2.4 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KUM55904.1 - 2.2e-15 56.8 0.0 6.6e-15 55.2 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KUM55904.1 - 4.8e-15 55.9 0.0 1.4e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KUM55904.1 - 3.9e-08 33.2 0.3 2.5e-07 30.6 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KUM55904.1 - 2.9e-05 24.4 0.1 8.7e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KUM55904.1 - 0.00016 22.0 0.5 0.00046 20.5 0.2 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KUM55904.1 - 0.00025 20.8 0.0 0.00068 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KUM55904.1 - 0.0013 18.1 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KUM55904.1 - 0.0021 17.2 0.0 0.0061 15.7 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 KUM55904.1 - 0.0036 17.0 0.4 0.015 14.9 0.4 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KUM55904.1 - 0.0036 17.1 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KUM55904.1 - 0.0073 16.3 0.1 2.7 8.0 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KUM55904.1 - 0.0078 16.3 0.2 0.05 13.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KUM55904.1 - 0.0089 16.0 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_7 PF12775.7 KUM55904.1 - 0.017 14.6 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 KUM55904.1 - 0.027 13.8 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 KUM55904.1 - 0.028 14.8 0.0 0.064 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KUM55904.1 - 0.033 14.3 2.2 0.066 13.4 0.0 2.7 3 1 0 3 3 3 0 AAA domain PhoH PF02562.16 KUM55904.1 - 0.062 12.8 0.0 0.2 11.1 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 KUM55904.1 - 0.062 13.2 0.6 0.62 10.0 0.1 2.5 3 0 0 3 3 2 0 NACHT domain ABC_tran PF00005.27 KUM55904.1 - 0.081 13.4 0.0 0.28 11.7 0.0 1.9 2 0 0 2 2 1 0 ABC transporter cobW PF02492.19 KUM55904.1 - 0.11 12.1 0.1 0.6 9.7 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Microtub_bd PF16796.5 KUM55904.1 - 0.13 12.2 0.0 2.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Microtubule binding CBFD_NFYB_HMF PF00808.23 KUM55905.1 - 1e-29 102.6 1.0 1.4e-29 102.2 1.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KUM55905.1 - 2.3e-06 28.0 0.3 3.1e-06 27.6 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KUM55905.1 - 0.00039 20.4 0.0 0.00057 19.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KUM55905.1 - 0.0007 19.5 0.1 0.0011 18.9 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 KUM55905.1 - 0.0018 18.3 0.0 0.0024 18.0 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 KUM55905.1 - 0.021 15.3 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A UDPG_MGDP_dh_N PF03721.14 KUM55908.1 - 6.4e-50 169.3 0.0 7.7e-32 110.4 0.1 2.5 2 1 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KUM55908.1 - 2.2e-29 101.5 0.0 1.2e-28 99.1 0.0 2.3 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KUM55908.1 - 6.3e-21 74.8 0.0 1.7e-16 60.6 0.0 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 KUM55908.1 - 0.0037 17.5 0.0 0.012 15.9 0.0 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain IKKbetaNEMObind PF12179.8 KUM55910.1 - 0.15 12.1 3.3 0.15 12.1 0.7 2.3 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain CDC45 PF02724.14 KUM55910.1 - 0.29 9.4 3.0 0.39 9.0 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 KUM55910.1 - 1.1 8.6 8.9 1.6 8.1 8.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PNP_UDP_1 PF01048.20 KUM55911.1 - 0.00062 19.1 0.4 0.0023 17.3 0.4 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KUM55912.1 - 7.4e-14 52.0 0.1 1.5e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Rcd1 PF04078.13 KUM55912.1 - 0.0039 16.5 0.0 0.0086 15.4 0.0 1.5 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like OTT_1508_deam PF14441.6 KUM55913.1 - 3.8e-19 68.4 0.4 7.2e-19 67.6 0.4 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase VanZ PF04892.12 KUM55914.1 - 3.5e-06 27.7 1.8 6.2e-06 26.9 1.8 1.4 1 1 0 1 1 1 1 VanZ like family Phage_holin_2_4 PF16082.5 KUM55914.1 - 0.016 14.9 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Bromodomain PF00439.25 KUM55915.1 - 4.5e-17 61.9 0.0 9.9e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 KUM55915.1 - 1.5e-09 37.7 0.0 5.4e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 Bromodomain associated PBP1_TM PF14812.6 KUM55915.1 - 0.13 12.7 14.4 0.11 12.8 8.3 3.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Exonuc_VII_L PF02601.15 KUM55915.1 - 8.9 5.8 9.9 1.6 8.2 4.7 2.3 2 1 0 2 2 2 0 Exonuclease VII, large subunit Y_phosphatase PF00102.27 KUM55916.1 - 8.3e-53 179.4 0.0 1e-52 179.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KUM55916.1 - 0.0032 17.6 0.0 0.011 15.9 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KUM55916.1 - 0.0034 17.4 0.0 0.006 16.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KUM55916.1 - 0.019 14.8 1.4 0.087 12.6 1.4 2.1 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain tRNA-synt_2b PF00587.25 KUM55917.1 - 8.1e-20 71.5 0.0 1e-19 71.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) BTB PF00651.31 KUM55918.1 - 0.0016 18.6 0.0 0.011 15.9 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain ABC_membrane PF00664.23 KUM55919.1 - 6.1e-70 236.0 32.7 1e-45 156.5 14.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KUM55919.1 - 3.1e-63 212.4 0.0 4.7e-33 114.6 0.0 3.1 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KUM55919.1 - 7.6e-16 58.2 1.3 7.2e-05 22.3 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KUM55919.1 - 1.8e-09 38.0 0.3 0.0071 16.6 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KUM55919.1 - 1.2e-08 35.6 0.2 0.00065 20.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KUM55919.1 - 1.8e-07 31.2 0.0 0.0051 16.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KUM55919.1 - 2.3e-07 30.4 0.5 0.00063 19.4 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KUM55919.1 - 8.4e-07 29.1 0.7 0.85 9.4 0.0 4.0 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KUM55919.1 - 1.2e-06 28.5 0.0 0.015 15.0 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KUM55919.1 - 2.9e-06 27.7 1.1 1.6 9.2 0.0 4.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KUM55919.1 - 2.1e-05 25.1 4.7 0.23 11.9 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KUM55919.1 - 2.9e-05 23.9 0.9 0.19 11.4 0.0 3.3 5 0 0 5 5 3 2 AAA domain Rad17 PF03215.15 KUM55919.1 - 8e-05 22.6 0.1 0.12 12.2 0.0 2.8 3 0 0 3 3 2 2 Rad17 P-loop domain AAA_7 PF12775.7 KUM55919.1 - 9.1e-05 22.0 0.0 0.49 9.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_5 PF07728.14 KUM55919.1 - 9.9e-05 22.4 0.0 0.49 10.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KUM55919.1 - 0.00022 21.4 0.0 0.73 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KUM55919.1 - 0.00034 21.1 0.0 0.84 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KUM55919.1 - 0.00039 20.7 0.0 0.34 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KUM55919.1 - 0.00043 19.9 0.0 0.85 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KUM55919.1 - 0.0014 18.4 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KUM55919.1 - 0.0016 18.7 3.3 1.1 9.5 0.2 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 KUM55919.1 - 0.0033 17.1 0.1 3.9 7.1 0.0 2.8 3 0 0 3 3 2 2 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 KUM55919.1 - 0.0081 15.9 0.7 24 4.6 0.0 3.6 4 0 0 4 4 3 0 IstB-like ATP binding protein PRK PF00485.18 KUM55919.1 - 0.015 15.0 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 KUM55919.1 - 0.015 15.7 0.0 6.2 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 KUM55919.1 - 0.02 14.7 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 KUM55919.1 - 0.023 13.9 0.1 2.1 7.5 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain G-alpha PF00503.20 KUM55919.1 - 0.035 13.3 0.1 8.3 5.5 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit Mg_chelatase PF01078.21 KUM55919.1 - 0.054 12.9 0.0 2 7.7 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KUM55919.1 - 0.056 12.7 0.0 13 5.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 KUM55919.1 - 0.066 13.6 0.5 22 5.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 KUM55919.1 - 0.085 12.9 0.2 26 4.9 0.0 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase APS_kinase PF01583.20 KUM55919.1 - 0.085 12.7 0.0 6.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase ATP-synt_ab PF00006.25 KUM55919.1 - 0.15 11.7 0.5 18 4.9 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_membrane PF00664.23 KUM55920.1 - 0.12 12.0 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region MBOAT PF03062.19 KUM55922.1 - 2.5e-47 162.0 20.2 3.7e-47 161.4 20.2 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KUM55922.1 - 0.0078 16.5 2.0 0.021 15.1 2.0 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PCI PF01399.27 KUM55923.1 - 0.00029 21.3 0.0 0.00053 20.5 0.0 1.4 1 0 0 1 1 1 1 PCI domain Phage_Mu_Gam PF07352.12 KUM55923.1 - 0.095 12.6 1.0 0.16 11.9 1.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF1192 PF06698.11 KUM55923.1 - 0.18 11.9 4.2 0.35 11.0 3.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) DUF3584 PF12128.8 KUM55923.1 - 0.21 9.1 0.7 0.28 8.6 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CSN7a_helixI PF18392.1 KUM55923.1 - 0.32 10.9 1.3 0.65 9.9 1.0 1.6 1 1 1 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain Ost5 PF05251.12 KUM55925.1 - 7.1e-16 58.2 9.0 8.2e-16 58.0 9.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Herpes_UL49_5 PF05702.11 KUM55925.1 - 0.8 9.8 3.8 1.1 9.4 0.1 2.0 1 1 1 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein RGS PF00615.19 KUM55926.1 - 4.7e-12 46.2 0.0 7.4e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain NMN_transporter PF04973.12 KUM55926.1 - 0.11 12.4 5.0 0.21 11.5 5.0 1.5 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter Bromodomain PF00439.25 KUM55927.1 - 4.1e-23 81.3 0.8 8.3e-23 80.3 0.8 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KUM55927.1 - 2.3e-08 34.3 0.0 4.4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KUM55927.1 - 7.7e-07 29.1 0.1 1.9e-06 27.9 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KUM55927.1 - 0.00021 21.6 0.1 0.00037 20.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Rad1 PF02144.16 KUM55928.1 - 4e-93 311.5 0.0 4.6e-93 311.3 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF1751 PF08551.10 KUM55929.1 - 1.5e-28 99.3 2.5 3.2e-28 98.2 2.5 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KUM55929.1 - 2.9e-05 24.1 5.7 5.4e-05 23.2 5.7 1.4 1 0 0 1 1 1 1 Rhomboid family ADH_zinc_N PF00107.26 KUM55930.1 - 8.3e-11 42.0 0.0 1.9e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM55930.1 - 2.9e-09 36.8 0.3 3.2e-07 30.2 0.1 2.8 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 KUM55931.1 - 1.9e-41 142.1 45.7 2.2e-41 142.0 43.4 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM55931.1 - 4.9e-16 58.3 27.1 6.7e-16 57.8 27.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM55931.1 - 3.1e-12 46.1 15.0 3.1e-12 46.1 15.0 3.0 2 1 0 3 3 3 2 Sugar (and other) transporter Zn_clus PF00172.18 KUM55932.1 - 1.3e-06 28.4 6.8 2.3e-06 27.6 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 KUM55933.1 - 1.6e-65 221.2 0.0 1.9e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 KUM55933.1 - 4.1e-06 26.4 0.1 6.2e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KUM55933.1 - 0.06 13.2 0.5 0.15 11.9 0.4 1.7 1 1 1 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.22 KUM55934.1 - 7.9e-51 173.2 0.0 9.2e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SRF-TF PF00319.18 KUM55939.1 - 1.6e-07 30.7 0.1 2.5e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) OrfB_Zn_ribbon PF07282.11 KUM55941.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF3435 PF11917.8 KUM55942.1 - 2.6e-161 537.2 0.0 3.7e-161 536.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2_4 PF13894.6 KUM55942.1 - 0.0094 16.7 3.8 0.085 13.7 0.6 3.1 2 0 0 2 2 2 1 C2H2-type zinc finger TRCF PF03461.15 KUM55942.1 - 0.035 14.5 0.3 0.1 13.0 0.3 1.7 1 0 0 1 1 1 0 TRCF domain zf-C2H2 PF00096.26 KUM55942.1 - 0.15 12.6 3.3 0.83 10.2 0.6 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type GET2 PF08690.10 KUM55942.1 - 0.25 11.0 3.4 0.57 9.8 3.4 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 Kri1 PF05178.12 KUM55942.1 - 0.52 10.9 8.0 1.2 9.8 8.0 1.6 1 0 0 1 1 1 0 KRI1-like family DUF4407 PF14362.6 KUM55942.1 - 0.57 9.5 4.8 1.1 8.6 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) C_Hendra PF16821.5 KUM55942.1 - 0.7 9.8 3.3 1.4 8.7 3.3 1.4 1 0 0 1 1 1 0 C protein from hendra and measles viruses CHZ PF09649.10 KUM55943.1 - 5.8e-13 48.1 1.6 5.8e-13 48.1 1.6 2.3 2 1 0 2 2 2 1 Histone chaperone domain CHZ DUF2012 PF09430.10 KUM55945.1 - 2.5e-30 105.1 0.0 3.3e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) NCE101 PF11654.8 KUM55946.1 - 4.7e-09 35.8 0.1 1.1e-08 34.7 0.0 1.6 2 0 0 2 2 2 1 Non-classical export protein 1 HSP70 PF00012.20 KUM55947.1 - 8.5e-262 869.7 7.1 9.7e-262 869.5 7.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KUM55947.1 - 4.6e-18 65.1 0.1 2.1e-17 62.9 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KUM55947.1 - 0.0013 18.5 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KUM55947.1 - 0.0044 17.4 4.5 4.7 7.7 0.0 3.6 3 2 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.20 KUM55947.1 - 0.0095 15.5 0.1 0.78 9.2 0.0 2.3 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 KUM55947.1 - 0.029 13.6 0.1 0.06 12.6 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 KUM55947.1 - 0.045 13.0 0.0 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 StbA protein PMBR PF09373.10 KUM55947.1 - 0.074 13.2 0.1 0.44 10.8 0.1 2.3 2 0 0 2 2 2 0 Pseudomurein-binding repeat OPT PF03169.15 KUM55948.1 - 2.2e-136 456.0 47.6 2.5e-136 455.8 47.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.6 KUM55948.1 - 0.14 11.5 0.4 0.38 10.1 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) PBP1_TM PF14812.6 KUM55949.1 - 0.028 14.8 9.1 0.055 13.8 9.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 KUM55949.1 - 0.5 10.0 2.8 0.91 9.2 2.8 1.4 1 0 0 1 1 1 0 FAM176 family WW PF00397.26 KUM55950.1 - 1.9e-11 43.9 1.3 1.9e-11 43.9 1.3 2.0 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.9 KUM55950.1 - 1.3e-08 35.3 21.3 1.3e-08 35.3 21.3 2.1 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) Polysacc_lyase PF14099.6 KUM55951.1 - 1.2e-56 191.9 9.4 1.3e-56 191.7 9.4 1.0 1 0 0 1 1 1 1 Polysaccharide lyase Triabin PF03973.13 KUM55951.1 - 0.013 15.3 0.3 0.032 14.1 0.1 1.7 2 0 0 2 2 2 0 Triabin Glyco_hydro_32N PF00251.20 KUM55952.1 - 4.5e-96 322.0 4.5 5.7e-96 321.7 4.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KUM55952.1 - 3.7e-33 114.8 1.8 6.7e-33 113.9 1.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.6 KUM55952.1 - 0.013 14.8 0.4 0.11 11.8 0.4 2.1 1 1 0 1 1 1 0 BNR repeat-like domain DUF4975 PF16346.5 KUM55952.1 - 0.028 14.5 0.5 0.086 12.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4975) FliD_N PF02465.18 KUM55952.1 - 0.065 13.9 0.9 0.16 12.7 0.9 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus CHB_HEX_C PF03174.13 KUM55952.1 - 0.1 12.6 0.2 0.45 10.5 0.1 2.1 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain Sugar_tr PF00083.24 KUM55954.1 - 3.3e-127 425.1 20.5 3.8e-127 424.9 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM55954.1 - 9.6e-23 80.7 50.6 5.1e-22 78.3 26.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GDP_Man_Dehyd PF16363.5 KUM55954.1 - 0.054 12.9 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ABC_membrane PF00664.23 KUM55955.1 - 1.3e-90 303.8 40.1 2.8e-48 164.9 21.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KUM55955.1 - 2.7e-68 228.7 0.0 5.8e-33 114.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KUM55955.1 - 4.5e-11 42.6 10.1 0.0008 18.9 0.0 5.1 4 2 1 6 6 6 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KUM55955.1 - 5.2e-09 36.7 0.8 0.00067 20.1 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KUM55955.1 - 2.6e-08 33.5 0.1 0.00058 19.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KUM55955.1 - 3.2e-08 34.0 1.6 0.012 15.8 0.1 3.9 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KUM55955.1 - 1.3e-06 28.4 0.0 0.072 13.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KUM55955.1 - 2.1e-06 26.8 0.2 0.031 13.1 0.1 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 KUM55955.1 - 7.3e-06 25.8 0.6 0.32 10.7 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KUM55955.1 - 8.4e-06 25.7 0.0 0.0021 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KUM55955.1 - 0.00014 21.4 0.5 0.25 10.9 0.0 2.8 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_25 PF13481.6 KUM55955.1 - 0.00067 19.3 0.2 2.7 7.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 KUM55955.1 - 0.00075 20.0 7.1 0.066 13.7 0.1 2.9 4 0 0 4 4 2 2 AAA domain AAA_5 PF07728.14 KUM55955.1 - 0.00079 19.4 0.0 2.7 8.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KUM55955.1 - 0.00095 19.6 1.6 4.9 7.6 0.5 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KUM55955.1 - 0.0011 18.8 4.7 1.9 8.2 0.1 3.8 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_ab PF00006.25 KUM55955.1 - 0.0023 17.6 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 KUM55955.1 - 0.0025 18.1 0.2 0.17 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KUM55955.1 - 0.0037 17.4 0.0 3.7 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KUM55955.1 - 0.0038 16.4 0.4 0.84 8.8 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain G-alpha PF00503.20 KUM55955.1 - 0.0058 15.8 0.1 0.52 9.4 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit Zeta_toxin PF06414.12 KUM55955.1 - 0.0077 15.5 0.0 1.5 8.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin SbcCD_C PF13558.6 KUM55955.1 - 0.01 16.0 1.8 3.4 7.9 0.1 3.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 KUM55955.1 - 0.014 15.2 0.1 3.9 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KUM55955.1 - 0.017 14.8 0.7 2.5 7.8 0.0 3.5 4 0 0 4 4 3 0 IstB-like ATP binding protein Rad17 PF03215.15 KUM55955.1 - 0.018 14.9 0.0 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_18 PF13238.6 KUM55955.1 - 0.029 14.9 0.0 7.7 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KUM55955.1 - 0.03 13.7 0.0 0.52 9.7 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KUM55955.1 - 0.03 14.4 0.0 9 6.3 0.0 3.5 4 0 0 4 4 3 0 AAA domain Synapsin_N PF10581.9 KUM55955.1 - 0.034 14.1 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 Synapsin N-terminal SRP54 PF00448.22 KUM55955.1 - 0.049 13.2 0.0 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 KUM55955.1 - 0.075 13.1 0.0 16 5.6 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KUM55955.1 - 0.075 13.4 0.0 14 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase TniB PF05621.11 KUM55955.1 - 0.089 12.2 0.6 19 4.6 0.0 3.4 4 0 0 4 4 3 0 Bacterial TniB protein PRK PF00485.18 KUM55955.1 - 0.12 12.1 0.2 6.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Seryl_tRNA_N PF02403.22 KUM55956.1 - 1.4e-10 41.3 3.4 5.6e-10 39.4 3.4 1.9 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain GOLGA2L5 PF15070.6 KUM55956.1 - 2e-06 26.8 2.3 2.7e-06 26.3 2.3 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 DivIC PF04977.15 KUM55956.1 - 0.0026 17.5 1.7 0.42 10.4 0.1 2.5 2 0 0 2 2 2 1 Septum formation initiator CENP-F_leu_zip PF10473.9 KUM55956.1 - 0.0071 16.4 3.6 0.17 11.9 0.1 2.3 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KUM55956.1 - 0.036 13.0 6.0 0.062 12.2 6.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.21 KUM55956.1 - 0.039 14.1 8.1 0.11 12.6 0.1 2.9 3 0 0 3 3 3 0 bZIP transcription factor JIP_LZII PF16471.5 KUM55956.1 - 0.057 13.6 8.5 0.69 10.1 2.5 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II LPP PF04728.13 KUM55956.1 - 0.071 13.5 1.4 6.2 7.3 0.3 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Jnk-SapK_ap_N PF09744.9 KUM55956.1 - 0.085 13.1 4.0 0.18 12.0 4.0 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ZapB PF06005.12 KUM55956.1 - 0.09 13.2 5.2 27 5.3 5.2 2.5 1 1 0 1 1 1 0 Cell division protein ZapB TMCO5 PF14992.6 KUM55956.1 - 0.15 11.6 5.2 0.24 10.9 5.2 1.2 1 0 0 1 1 1 0 TMCO5 family DUF4200 PF13863.6 KUM55956.1 - 0.18 12.2 4.2 1.6 9.1 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) BLOC1_2 PF10046.9 KUM55956.1 - 0.25 11.7 1.8 1.5 9.2 0.1 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 KUM55956.1 - 0.42 10.7 6.9 5.1 7.2 0.4 2.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein betaPIX_CC PF16523.5 KUM55956.1 - 0.55 10.1 3.2 1.2 9.1 0.2 2.3 2 0 0 2 2 2 0 betaPIX coiled coil FapA PF03961.13 KUM55956.1 - 0.65 8.5 3.0 0.99 7.9 3.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spectrin PF00435.21 KUM55956.1 - 0.91 10.0 6.7 0.7 10.4 1.7 2.2 1 1 1 2 2 2 0 Spectrin repeat ATG16 PF08614.11 KUM55956.1 - 0.99 9.6 9.8 0.51 10.5 1.0 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Csm1_N PF18504.1 KUM55956.1 - 1.2 9.5 9.4 0.68 10.3 0.7 2.8 2 1 1 3 3 2 0 Csm1 N-terminal domain PI3K_P85_iSH2 PF16454.5 KUM55956.1 - 1.5 8.4 9.2 1.9 8.1 1.1 2.3 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TMF_TATA_bd PF12325.8 KUM55956.1 - 1.6 9.0 7.3 6.8 6.9 1.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ABC_tran_CTD PF16326.5 KUM55956.1 - 3.3 8.0 6.8 5.6 7.3 2.4 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain Swi5 PF07061.11 KUM55956.1 - 4.3 7.5 5.8 14 5.8 0.7 2.4 2 0 0 2 2 2 0 Swi5 TMF_DNA_bd PF12329.8 KUM55956.1 - 5.1 7.2 10.5 6.8 6.8 7.8 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Cnn_1N PF07989.11 KUM55956.1 - 5.5 7.2 7.3 20 5.4 0.3 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF4140 PF13600.6 KUM55956.1 - 7.6 7.0 7.8 7.8 7.0 1.8 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cytochrom_B561 PF03188.16 KUM55957.1 - 1.1e-15 58.0 4.9 1.1e-15 58.0 4.9 1.9 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF4271 PF14093.6 KUM55957.1 - 0.046 13.6 3.4 0.068 13.1 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) DUF5090 PF17009.5 KUM55957.1 - 0.24 11.3 2.9 0.41 10.6 3.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5090) DUF3784 PF12650.7 KUM55957.1 - 0.38 11.0 7.4 1.6 9.0 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) DUF5373 PF17343.2 KUM55957.1 - 1.1 9.1 7.4 0.36 10.7 4.4 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5373) DUF4079 PF13301.6 KUM55957.1 - 2.1 8.5 15.3 18 5.4 6.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF1056 PF06341.11 KUM55957.1 - 4.8 7.6 8.7 8.3 6.8 0.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1056) DUF1129 PF06570.11 KUM55957.1 - 6.6 6.2 6.8 11 5.4 6.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Zn_clus PF00172.18 KUM55958.1 - 3.2e-06 27.2 17.0 4.1e-06 26.8 12.7 2.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM55958.1 - 0.0016 17.5 0.2 0.0025 16.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain WAC_Acf1_DNA_bd PF10537.9 KUM55959.1 - 2.5e-39 133.9 0.1 2.5e-39 133.9 0.1 2.7 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KUM55959.1 - 9.9e-23 80.5 3.5 3.2e-22 78.9 0.3 3.3 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KUM55959.1 - 4.7e-17 62.1 2.3 9.7e-17 61.0 2.3 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KUM55959.1 - 3.5e-06 26.4 0.2 8.6e-06 25.2 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Alg6_Alg8 PF03155.15 KUM55961.1 - 6.8e-174 579.4 30.5 7.9e-174 579.2 30.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.13 KUM55963.1 - 4.4e-27 94.9 0.0 6.6e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family BBP1_C PF15272.6 KUM55963.1 - 0.039 13.8 2.0 0.058 13.2 2.0 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Stevor PF17410.2 KUM55963.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4763 PF15960.5 KUM55963.1 - 0.21 10.9 5.7 0.32 10.3 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF5385 PF17359.2 KUM55963.1 - 1.7 8.2 5.5 0.18 11.3 1.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5385) PHD PF00628.29 KUM55964.1 - 3.7e-17 62.0 24.9 1.4e-10 40.9 10.6 2.6 2 0 0 2 2 2 2 PHD-finger AIRC PF00731.20 KUM55964.1 - 0.0046 16.5 0.5 0.0079 15.8 0.5 1.2 1 0 0 1 1 1 1 AIR carboxylase zf-RanBP PF00641.18 KUM55964.1 - 0.017 14.5 0.2 0.017 14.5 0.2 2.9 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others PHD_2 PF13831.6 KUM55964.1 - 0.51 9.9 16.5 0.27 10.8 0.5 3.6 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.22 KUM55964.1 - 7.1 6.6 23.3 0.13 12.1 4.5 2.7 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HCO3_cotransp PF00955.21 KUM55965.1 - 3.2e-34 118.6 4.2 4.7e-32 111.5 1.0 2.1 1 1 1 2 2 2 2 HCO3- transporter family DUF1382 PF07131.11 KUM55965.1 - 0.22 11.6 0.4 0.47 10.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) CorA PF01544.18 KUM55966.1 - 5.6e-44 150.6 0.0 7e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SET PF00856.28 KUM55967.1 - 7.3e-09 36.2 0.1 9.5e-08 32.6 0.0 2.3 2 1 0 3 3 3 1 SET domain Methyltransf_3 PF01596.17 KUM55968.1 - 1.5e-14 53.7 0.0 2.1e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KUM55968.1 - 7e-11 43.1 0.0 1.1e-10 42.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 KUM55968.1 - 0.044 13.5 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase FAD_binding_3 PF01494.19 KUM55969.1 - 2.3e-87 293.5 0.0 8.8e-87 291.6 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KUM55969.1 - 8.3e-38 130.0 0.0 2.1e-37 128.7 0.0 1.7 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 KUM55969.1 - 2.5e-06 26.8 0.4 3.8e-06 26.2 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KUM55969.1 - 6.8e-06 25.0 0.2 1e-05 24.5 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KUM55969.1 - 7.1e-06 25.6 0.7 1.3e-05 24.8 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM55969.1 - 2.1e-05 23.9 0.1 9.5e-05 21.8 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM55969.1 - 4.2e-05 23.3 0.0 6.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KUM55969.1 - 0.00021 20.6 0.1 0.00038 19.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KUM55969.1 - 0.00034 19.8 0.2 0.00056 19.1 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KUM55969.1 - 0.00053 20.2 0.1 0.0012 19.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KUM55969.1 - 0.00075 18.8 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KUM55969.1 - 0.027 13.6 0.4 0.043 12.9 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 KUM55969.1 - 0.042 14.4 0.2 0.17 12.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KUM55969.1 - 0.083 11.7 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KUM55969.1 - 0.14 11.4 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KUM55969.1 - 0.18 11.3 0.2 0.98 9.0 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Arrestin_N PF00339.29 KUM55970.1 - 0.028 14.5 0.1 0.031 14.3 0.1 1.1 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Zip PF02535.22 KUM55971.1 - 1.3e-34 119.9 14.9 1e-25 90.7 4.9 3.0 1 1 1 2 2 2 2 ZIP Zinc transporter Zn_clus PF00172.18 KUM55972.1 - 4.9e-07 29.8 13.5 9e-07 28.9 13.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM55972.1 - 0.0001 21.3 0.3 0.0025 16.7 0.1 2.8 3 1 0 3 3 3 1 Fungal specific transcription factor domain RTA1 PF04479.13 KUM55973.1 - 3.5e-52 177.0 6.4 3.5e-52 177.0 6.4 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF4131 PF13567.6 KUM55973.1 - 0.0087 15.7 4.8 0.055 13.1 0.3 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) MFS_1 PF07690.16 KUM55975.1 - 1.6e-35 122.7 24.3 1.6e-35 122.7 24.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM55975.1 - 2.7e-09 36.4 6.6 2.7e-09 36.4 6.6 3.4 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KUM55975.1 - 1.5e-05 23.6 3.7 2.4e-05 23.0 3.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UL42 PF17638.2 KUM55975.1 - 0.047 13.7 0.1 0.17 11.9 0.1 1.9 1 0 0 1 1 1 0 HCMV UL42 CTNNBL PF08216.11 KUM55975.1 - 0.078 13.2 0.3 0.21 11.8 0.1 1.7 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear HemY_N PF07219.13 KUM55975.1 - 0.62 10.3 7.3 0.3 11.3 0.9 3.2 3 0 0 3 3 3 0 HemY protein N-terminus Lyase_aromatic PF00221.19 KUM55976.1 - 1.1e-147 492.5 8.2 1.4e-147 492.1 8.2 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Bud13 PF09736.9 KUM55977.1 - 5.7e-48 163.0 8.4 5.7e-48 163.0 8.4 2.8 2 1 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex WDCP PF15390.6 KUM55977.1 - 0.33 9.3 1.5 0.43 8.9 1.5 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family SPATIAL PF15256.6 KUM55977.1 - 2.7 8.3 7.2 3.7 7.9 6.4 1.6 1 1 0 1 1 1 0 SPATIAL RR_TM4-6 PF06459.12 KUM55977.1 - 8.8 6.1 13.6 16 5.2 13.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Brr6_like_C_C PF10104.9 KUM55978.1 - 1.6e-42 144.4 0.8 2.2e-42 144.0 0.8 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain PBP1_TM PF14812.6 KUM55978.1 - 0.18 12.2 5.2 0.33 11.3 3.6 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_binding_1 PF01035.20 KUM55979.1 - 8.3e-25 86.7 0.1 1.1e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Pkinase PF00069.25 KUM55980.1 - 1.3e-41 142.8 0.3 2.7e-22 79.4 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KUM55980.1 - 8.5e-15 54.7 0.6 3.1e-10 39.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KUM55980.1 - 0.061 12.1 0.0 0.098 11.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Phage_Gp23 PF10669.9 KUM55980.1 - 0.44 10.9 2.5 0.38 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Metallophos PF00149.28 KUM55981.1 - 4.2e-11 43.7 0.1 1.5e-10 41.9 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KUM55981.1 - 3.2e-05 24.2 1.1 0.0018 18.5 0.2 2.2 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain FMN_dh PF01070.18 KUM55982.1 - 1.8e-121 405.5 0.0 2.1e-121 405.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KUM55982.1 - 4.2e-23 81.3 0.0 8.4e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KUM55982.1 - 6.4e-07 28.8 0.1 1e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KUM55982.1 - 9.5e-05 21.9 0.1 0.00017 21.1 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KUM55982.1 - 0.00027 20.0 0.1 0.00076 18.6 0.0 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KUM55982.1 - 0.037 13.5 0.3 1.2 8.5 0.1 2.4 1 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 KUM55982.1 - 0.057 12.7 0.0 8.2 5.7 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 KUM55982.1 - 0.094 11.9 0.1 2.3 7.3 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF561) TPR_12 PF13424.6 KUM55983.1 - 3.9e-206 667.9 70.5 2.4e-20 72.6 0.4 10.8 3 2 10 13 13 13 13 Tetratricopeptide repeat TPR_10 PF13374.6 KUM55983.1 - 2.1e-182 586.9 35.5 6.7e-13 48.1 0.0 15.9 16 0 0 16 16 16 15 Tetratricopeptide repeat TPR_7 PF13176.6 KUM55983.1 - 8.9e-75 241.4 32.9 3.2e-05 23.7 0.0 16.3 16 0 0 16 16 15 15 Tetratricopeptide repeat TPR_1 PF00515.28 KUM55983.1 - 9.4e-63 205.7 25.6 0.0021 17.8 0.1 15.5 15 0 0 15 15 15 15 Tetratricopeptide repeat TPR_8 PF13181.6 KUM55983.1 - 1.8e-36 121.3 25.0 0.37 11.1 0.0 15.4 15 0 0 15 15 15 11 Tetratricopeptide repeat TPR_14 PF13428.6 KUM55983.1 - 2.3e-29 99.6 31.2 0.67 10.9 0.0 15.7 15 0 0 15 15 15 7 Tetratricopeptide repeat TPR_16 PF13432.6 KUM55983.1 - 3.2e-25 88.5 29.2 0.0049 17.5 0.3 12.3 8 4 4 12 12 12 7 Tetratricopeptide repeat TPR_2 PF07719.17 KUM55983.1 - 3e-24 83.1 33.4 0.86 9.9 1.0 15.4 15 0 0 15 15 15 4 Tetratricopeptide repeat TPR_17 PF13431.6 KUM55983.1 - 4.3e-23 80.0 3.6 3.4 8.3 0.0 14.3 14 0 0 14 14 14 2 Tetratricopeptide repeat TPR_4 PF07721.14 KUM55983.1 - 2.7e-21 73.9 0.6 7 7.6 0.0 14.6 15 0 0 15 15 15 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KUM55983.1 - 6.7e-21 75.0 20.0 3.7e-07 29.8 0.9 4.6 1 1 5 6 6 6 6 MalT-like TPR region TPR_19 PF14559.6 KUM55983.1 - 2.6e-17 63.1 21.8 0.017 15.6 0.1 9.3 3 1 9 12 12 12 9 Tetratricopeptide repeat DUF1925 PF09094.11 KUM55983.1 - 2.8e-13 50.0 24.9 10 6.5 0.0 14.7 8 4 7 15 15 15 0 Domain of unknown function (DUF1925) ANAPC3 PF12895.7 KUM55983.1 - 3.1e-13 49.7 7.2 0.2 11.9 0.4 9.1 4 3 3 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 KUM55983.1 - 1e-11 44.2 22.8 0.66 10.3 0.0 12.5 14 0 0 14 14 14 2 PPR repeat NRBF2_MIT PF17169.4 KUM55983.1 - 4.4e-11 42.9 22.2 35 4.7 0.0 13.8 12 2 2 14 14 14 0 MIT domain of nuclear receptor-binding factor 2 MIT PF04212.18 KUM55983.1 - 1.6e-06 28.0 16.0 27 4.9 0.0 10.7 11 1 1 12 12 10 0 MIT (microtubule interacting and transport) domain TPR_5 PF12688.7 KUM55983.1 - 6.7e-06 26.3 24.6 1.5 9.1 0.7 7.8 3 1 2 7 7 6 3 Tetratrico peptide repeat Sfi1 PF08457.10 KUM55983.1 - 0.0012 17.5 0.0 0.005 15.4 0.0 2.1 1 0 0 1 1 1 1 Sfi1 spindle body protein AAA_16 PF13191.6 KUM55983.1 - 0.0013 19.2 0.4 0.0079 16.6 0.1 2.6 2 1 0 2 2 1 1 AAA ATPase domain ISG65-75 PF11727.8 KUM55983.1 - 0.0042 16.4 14.5 0.37 10.0 0.1 5.8 3 2 4 7 7 7 2 Invariant surface glycoprotein TPR_3 PF07720.12 KUM55983.1 - 0.022 14.8 22.2 1.7 8.7 0.0 11.1 15 0 0 15 15 14 0 Tetratricopeptide repeat DUF5112 PF17139.4 KUM55983.1 - 0.054 13.0 4.1 18 4.7 0.1 4.9 3 2 2 5 5 5 0 Domain of unknown function (DUF5112) Pro-NT_NN PF07421.11 KUM55983.1 - 0.22 11.8 4.9 1.7e+02 2.4 0.0 5.5 1 1 3 6 6 6 0 Neurotensin/neuromedin N precursor DUF3095 PF11294.8 KUM55983.1 - 0.46 9.5 2.9 31 3.5 0.0 4.2 3 1 1 6 6 6 0 Protein of unknown function (DUF3095) DDE_1 PF03184.19 KUM55984.1 - 7.5e-29 100.6 0.0 1.2e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KUM55984.1 - 1.8e-05 24.7 0.0 4.8e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 KUM55984.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Claudin_2 PF13903.6 KUM55985.1 - 0.017 14.9 0.1 0.025 14.3 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Helo_like_N PF17111.5 KUM55986.1 - 9.8e-09 34.9 0.1 1.1e-08 34.8 0.1 1.0 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KUM55986.1 - 0.0022 18.2 0.1 0.0026 17.9 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases BLOC1_2 PF10046.9 KUM55986.1 - 0.0087 16.3 0.4 0.16 12.3 0.0 2.2 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 KUM55986.1 - 0.012 16.0 3.0 0.14 12.6 0.3 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CREPT PF16566.5 KUM55986.1 - 0.019 15.2 0.3 0.036 14.2 0.3 1.5 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF3829 PF12889.7 KUM55986.1 - 0.021 14.3 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Casc1_N PF15927.5 KUM55986.1 - 0.023 14.4 0.1 0.032 13.9 0.1 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus CmlA_N PF18456.1 KUM55986.1 - 0.044 13.1 0.1 0.056 12.7 0.1 1.2 1 0 0 1 1 1 0 Diiron non-heme beta-hydroxylase N-terminal domain DUF1515 PF07439.11 KUM55986.1 - 0.092 12.8 0.2 0.28 11.2 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) NB-ARC PF00931.22 KUM55987.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KUM55987.1 - 0.21 12.1 0.2 0.54 10.8 0.1 1.7 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KUM55987.1 - 0.22 11.4 0.4 0.32 10.9 0.4 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 KUM55988.1 - 0.035 14.0 0.3 0.078 12.9 0.3 1.6 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.14 KUM55988.1 - 0.2 10.8 1.1 0.33 10.1 1.1 1.3 1 0 0 1 1 1 0 KAP family P-loop domain KH_2 PF07650.17 KUM55989.1 - 3.8e-06 26.6 0.8 1.1 9.2 0.1 3.1 2 1 1 3 3 3 3 KH domain HTH_Tnp_IS1 PF12759.7 KUM55989.1 - 0.043 13.4 0.6 40 3.9 0.1 3.1 3 0 0 3 3 3 0 InsA C-terminal domain KH_5 PF13184.6 KUM55989.1 - 0.094 12.8 0.6 49 4.1 0.0 3.1 2 1 1 3 3 3 0 NusA-like KH domain Glyco_hydro_18 PF00704.28 KUM55990.1 - 7.5e-81 272.3 4.0 8.7e-81 272.0 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AP_endonuc_2 PF01261.24 KUM55990.1 - 0.0079 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MFS_1 PF07690.16 KUM55991.1 - 2e-45 155.3 38.6 2e-45 155.3 38.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily DAP10 PF07213.11 KUM55991.1 - 0.11 12.5 0.8 5.1 7.1 0.0 2.6 2 0 0 2 2 2 0 DAP10 membrane protein TPT PF03151.16 KUM55992.1 - 3.5e-22 79.1 13.7 3.9e-22 78.9 13.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KUM55992.1 - 1.8e-05 24.1 15.7 2.2e-05 23.8 15.7 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KUM55992.1 - 0.00068 19.8 24.5 0.01 16.0 3.3 2.3 2 0 0 2 2 2 2 EamA-like transporter family Sugar_tr PF00083.24 KUM55994.1 - 4.6e-100 335.6 31.6 5.4e-100 335.4 31.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM55994.1 - 2.8e-26 92.3 41.6 8.6e-20 70.9 18.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L18A PF01775.17 KUM55996.1 - 1e-53 180.6 0.2 1.2e-53 180.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A CysA_C_terminal PF17850.1 KUM55996.1 - 0.17 12.5 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 CysA C-terminal regulatory domain CLTH PF10607.9 KUM55997.1 - 1.3e-30 106.3 0.0 2.1e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KUM55997.1 - 5.6e-08 32.7 0.1 1e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KUM55997.1 - 0.0002 20.8 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 KUM55997.1 - 0.00026 20.9 0.1 0.00044 20.1 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KUM55997.1 - 0.0011 19.2 0.3 0.0019 18.5 0.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KUM55997.1 - 0.0038 17.0 0.8 0.0068 16.2 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM55997.1 - 0.012 15.5 0.3 0.021 14.7 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KUM55997.1 - 0.016 15.1 0.7 0.029 14.2 0.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KUM55997.1 - 0.028 14.3 0.4 0.05 13.5 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PCI PF01399.27 KUM55998.1 - 3.7e-11 43.5 0.0 7e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 PCI domain ARID PF01388.21 KUM55998.1 - 0.15 12.8 0.0 0.61 10.8 0.0 2.0 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain BTB PF00651.31 KUM55999.1 - 0.00068 19.8 0.0 0.0035 17.5 0.0 2.1 3 0 0 3 3 3 1 BTB/POZ domain NAD_binding_1 PF00175.21 KUM56000.1 - 6.9e-33 113.6 0.0 1e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KUM56000.1 - 1.6e-22 79.7 0.0 4.2e-22 78.3 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KUM56000.1 - 1.3e-08 35.1 0.0 5.3e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Peptidase_M20 PF01546.28 KUM56004.1 - 1.3e-28 100.1 0.3 1.8e-28 99.7 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KUM56004.1 - 4.4e-06 26.6 0.0 9.8e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KUM56004.1 - 0.0052 16.5 0.1 0.41 10.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M28 Ribosomal_60s PF00428.19 KUM56005.1 - 0.29 11.8 16.3 0.24 12.0 1.9 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein adh_short_C2 PF13561.6 KUM56006.1 - 1.4e-49 168.8 0.1 1.9e-49 168.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM56006.1 - 1.1e-36 126.1 0.1 1.6e-36 125.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM56006.1 - 4.2e-12 46.3 0.1 6.6e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KUM56006.1 - 0.042 13.2 0.0 4.8 6.5 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Frag1 PF10277.9 KUM56012.1 - 1.9e-32 112.6 16.9 2.2e-32 112.4 16.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family 7TMR-DISM_7TM PF07695.11 KUM56012.1 - 5.1 6.9 19.6 0.16 11.9 13.7 1.5 2 0 0 2 2 2 0 7TM diverse intracellular signalling Glyco_hydro_18 PF00704.28 KUM56013.1 - 4e-66 223.9 3.5 4e-66 223.9 3.5 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 KUM56013.1 - 0.0018 17.7 0.4 0.0074 15.7 0.1 2.1 3 0 0 3 3 3 1 Glycosyl hydrolase family 85 adh_short_C2 PF13561.6 KUM56015.1 - 2.5e-36 125.4 0.4 6e-34 117.6 0.4 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM56015.1 - 4.6e-34 117.6 1.7 1.3e-33 116.1 0.3 2.4 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KUM56015.1 - 7.5e-07 29.2 0.8 1.5e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KUM56015.1 - 0.025 14.1 0.1 0.079 12.4 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 KUM56015.1 - 0.066 13.4 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KUM56015.1 - 0.078 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Nitro_FeMo-Co PF02579.17 KUM56015.1 - 0.13 12.7 0.1 0.26 11.7 0.1 1.5 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Glyco_tran_WecB PF03808.13 KUM56015.1 - 0.13 12.2 0.0 6.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Hemerythrin PF01814.23 KUM56016.1 - 4.3e-11 43.5 0.2 6.3e-11 43.0 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Nitroreductase PF00881.24 KUM56016.1 - 0.026 14.6 0.0 0.095 12.7 0.0 1.7 2 0 0 2 2 2 0 Nitroreductase family Methyltransf_2 PF00891.18 KUM56017.1 - 4.4e-25 88.2 0.0 4.8e-24 84.8 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KUM56017.1 - 0.0052 17.5 0.0 0.05 14.3 0.0 2.6 2 1 1 3 3 3 1 Methyltransferase domain CheR PF01739.18 KUM56017.1 - 0.032 13.7 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.12 KUM56017.1 - 0.079 13.7 0.0 0.3 11.9 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Cu-oxidase_2 PF07731.14 KUM56018.1 - 1.2e-22 80.1 3.6 4.4e-21 75.1 1.8 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KUM56018.1 - 2.2e-19 70.1 0.0 6.9e-19 68.5 0.0 1.8 1 1 0 1 1 1 1 Multicopper oxidase Fasciclin PF02469.22 KUM56019.1 - 6.8e-35 120.1 0.0 2.4e-21 76.3 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain DPBB_1 PF03330.18 KUM56019.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Lytic transglycolase AMP-binding PF00501.28 KUM56020.1 - 2.8e-138 461.1 0.0 1.5e-70 238.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KUM56020.1 - 3.8e-56 190.7 0.0 4.4e-25 88.3 0.0 3.4 2 1 0 3 3 3 3 Condensation domain PP-binding PF00550.25 KUM56020.1 - 1.5e-14 54.1 2.0 6e-06 26.5 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM56020.1 - 0.045 14.7 0.0 1.2 10.1 0.0 2.6 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain adh_short PF00106.25 KUM56022.1 - 4e-19 68.8 0.1 1.8e-17 63.4 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM56022.1 - 7.8e-10 38.7 0.2 4e-09 36.4 0.1 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM56022.1 - 9.5e-06 25.6 0.4 1.6e-05 24.9 0.4 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KUM56022.1 - 0.046 13.5 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CNPase PF05881.12 KUM56022.1 - 0.054 13.1 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) MFS_1 PF07690.16 KUM56023.1 - 7.5e-35 120.5 52.4 7.9e-34 117.1 52.4 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM56023.1 - 2.5e-09 36.5 17.5 2.5e-09 36.5 17.5 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter SH3_2 PF07653.17 KUM56024.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain BBE PF08031.12 KUM56025.1 - 1.7e-07 31.2 1.8 1.9e-07 31.0 0.3 2.0 2 0 0 2 2 2 1 Berberine and berberine like DUF2423 PF10338.9 KUM56026.1 - 5e-20 71.4 3.2 5e-20 71.4 3.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2423) Cucumo_2B PF03263.13 KUM56026.1 - 0.53 10.8 3.1 2.1 8.8 0.0 2.1 1 1 1 2 2 2 0 Cucumovirus protein 2B Phosphodiest PF01663.22 KUM56028.1 - 1.7e-12 47.7 2.6 2.1e-07 30.9 0.3 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KUM56028.1 - 1.1e-05 25.0 0.0 0.00049 19.6 0.0 2.2 2 0 0 2 2 2 2 Sulfatase DUF229 PF02995.17 KUM56028.1 - 0.099 11.2 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Ldh_1_C PF02866.18 KUM56029.1 - 6.6e-45 153.0 0.0 8.3e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KUM56029.1 - 7.2e-16 58.6 0.0 1.1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain TRAPP PF04051.16 KUM56030.1 - 1e-45 155.1 0.0 1.2e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PorB PF11565.8 KUM56030.1 - 0.21 12.0 0.0 0.39 11.2 0.0 1.4 1 0 0 1 1 1 0 Alpha helical Porin B DUF979 PF06166.12 KUM56031.1 - 0.071 12.3 0.2 0.089 11.9 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF979) PINIT PF14324.6 KUM56032.1 - 7.2e-40 136.7 0.5 1.2e-39 135.9 0.5 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KUM56032.1 - 1.8e-22 78.8 7.1 3.2e-22 78.0 7.1 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KUM56032.1 - 1.2e-07 31.4 2.8 3.5e-07 29.9 2.8 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KUM56032.1 - 0.00018 21.2 0.1 0.00045 19.9 0.1 1.7 1 0 0 1 1 1 1 SAP domain Prok-RING_4 PF14447.6 KUM56032.1 - 0.065 13.1 3.9 0.14 12.0 3.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FYVE_2 PF02318.16 KUM56032.1 - 0.24 11.6 1.8 0.45 10.8 1.8 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Glyco_hydro_18 PF00704.28 KUM56033.1 - 5.1e-47 161.1 7.5 9.6e-47 160.2 7.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KUM56033.1 - 3e-10 40.0 0.4 1.6e-05 24.9 0.0 3.7 3 1 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.19 KUM56033.1 - 6.5e-08 32.9 9.6 6.5e-08 32.9 9.6 4.1 4 2 0 4 4 4 1 Chitin recognition protein Hemopexin PF00045.19 KUM56034.1 - 0.25 11.3 10.8 6.5 6.8 4.3 3.3 2 1 0 2 2 2 0 Hemopexin SLAC1 PF03595.17 KUM56037.1 - 2.4e-76 257.1 45.1 2.7e-76 256.9 45.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel ATP-grasp_2 PF08442.10 KUM56038.1 - 3e-75 252.2 0.7 6e-75 251.2 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KUM56038.1 - 7.3e-25 87.6 0.3 1.3e-24 86.7 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KUM56038.1 - 9.8e-08 31.7 0.3 3e-07 30.1 0.1 1.9 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KUM56038.1 - 0.00063 19.6 0.8 0.035 13.9 0.1 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ribosomal_S11 PF00411.19 KUM56038.1 - 0.096 13.1 0.0 25 5.3 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein S11 adh_short PF00106.25 KUM56039.1 - 4.8e-43 146.9 0.0 6.2e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM56039.1 - 1.1e-28 100.4 0.0 1.4e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KUM56039.1 - 0.00034 20.1 0.0 0.00075 19.0 0.0 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KUM56039.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 KUM56039.1 - 0.078 12.5 0.0 0.17 11.4 0.0 1.7 1 1 0 1 1 1 0 NmrA-like family F-box PF00646.33 KUM56040.1 - 2.3e-06 27.3 1.0 1.5e-05 24.7 0.6 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KUM56040.1 - 0.00062 19.6 0.3 0.0015 18.4 0.3 1.7 1 0 0 1 1 1 1 F-box-like HSF_DNA-bind PF00447.17 KUM56041.1 - 1.9e-30 105.4 0.1 3.3e-30 104.6 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding AAA_12 PF13087.6 KUM56042.1 - 2.2e-35 122.1 0.0 4.8e-35 121.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KUM56042.1 - 2.9e-19 69.9 1.1 9.3e-19 68.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KUM56042.1 - 1.3e-07 32.0 0.4 2.3e-06 28.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KUM56042.1 - 3.8e-07 29.7 0.3 0.0041 16.4 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Torus PF16131.5 KUM56042.1 - 9.5e-07 29.5 0.6 3.3e-06 27.7 0.6 1.9 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 KUM56042.1 - 6.8e-06 26.0 7.4 1.8e-05 24.6 7.4 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KUM56042.1 - 5.5e-05 22.9 7.3 0.00019 21.1 7.3 2.1 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KUM56042.1 - 0.00015 21.6 5.8 0.00035 20.4 5.8 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_30 PF13604.6 KUM56042.1 - 0.00073 19.3 0.6 0.052 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KUM56042.1 - 0.022 14.1 1.5 0.16 11.4 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 KUM56042.1 - 0.12 12.4 0.0 0.39 10.7 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3425 PF11905.8 KUM56044.1 - 2.9e-23 82.2 1.0 6.1e-23 81.1 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KUM56044.1 - 1.4 9.1 8.6 2.4 8.3 8.6 1.3 1 0 0 1 1 1 0 bZIP transcription factor ACOX PF01756.19 KUM56045.1 - 8.2e-48 162.3 0.1 3.7e-47 160.2 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KUM56045.1 - 3.8e-28 98.5 1.1 8.8e-28 97.4 1.1 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KUM56045.1 - 4.7e-12 45.9 0.0 2.3e-11 43.7 0.0 2.2 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KUM56045.1 - 0.00013 22.2 0.5 0.2 11.9 0.0 2.5 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain polyprenyl_synt PF00348.17 KUM56046.1 - 5e-19 68.4 0.0 6.5e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Glyco_hydro_43 PF04616.14 KUM56047.1 - 1.1e-67 228.4 4.7 1.4e-67 228.1 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KUM56047.1 - 4e-19 69.1 0.0 6e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain MFS_1 PF07690.16 KUM56048.1 - 1.4e-23 83.4 50.3 1.7e-16 60.1 25.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CPP1-like PF11833.8 KUM56048.1 - 2.9 7.5 4.4 4.6 6.8 3.3 2.0 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Pkinase PF00069.25 KUM56049.1 - 1.8e-24 86.6 0.0 3.9e-16 59.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KUM56049.1 - 2.7e-07 30.1 0.0 9.3e-05 21.8 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KUM56049.1 - 0.14 12.1 0.0 0.5 10.3 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family TMF_DNA_bd PF12329.8 KUM56052.1 - 0.00027 20.9 35.1 0.0028 17.6 8.5 3.2 2 1 0 3 3 3 2 TATA element modulatory factor 1 DNA binding HAP1_N PF04849.13 KUM56052.1 - 0.00065 19.0 24.5 0.0012 18.1 14.5 2.2 1 1 1 2 2 2 1 HAP1 N-terminal conserved region AAA_13 PF13166.6 KUM56052.1 - 0.005 15.6 14.6 0.005 15.6 14.6 1.8 1 1 1 2 2 2 1 AAA domain ADIP PF11559.8 KUM56052.1 - 0.0089 16.1 28.6 0.12 12.5 6.2 3.1 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding YgbB PF02542.16 KUM56052.1 - 0.02 15.1 2.3 0.037 14.3 2.3 1.6 1 1 0 1 1 1 0 YgbB family Glutaredoxin2_C PF04399.13 KUM56052.1 - 0.035 13.9 5.7 0.98 9.3 0.8 2.4 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain Fib_alpha PF08702.10 KUM56052.1 - 0.1 12.8 23.7 0.067 13.4 11.7 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 KUM56052.1 - 0.13 12.5 27.2 3.9 7.7 27.3 2.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) HMMR_N PF15905.5 KUM56052.1 - 0.15 11.5 28.8 16 4.9 28.9 2.1 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal G-gamma PF00631.22 KUM56052.1 - 0.16 12.0 0.2 0.16 12.0 0.2 2.7 2 1 1 3 3 2 0 GGL domain NPV_P10 PF05531.12 KUM56052.1 - 0.18 12.3 10.1 1.1 9.7 0.8 3.2 1 1 2 3 3 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 KUM56052.1 - 0.2 11.9 5.1 0.13 12.5 2.3 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) KASH_CCD PF14662.6 KUM56052.1 - 0.24 11.2 29.2 0.48 10.2 19.8 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 KUM56052.1 - 0.27 10.1 28.8 0.22 10.4 10.8 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Med9 PF07544.13 KUM56052.1 - 0.37 10.9 19.0 0.78 9.9 2.3 4.0 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 TMF_TATA_bd PF12325.8 KUM56052.1 - 0.43 10.8 25.9 0.6 10.3 14.9 2.8 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 KUM56052.1 - 0.46 10.9 25.7 27 5.1 12.7 2.1 1 1 0 1 1 1 0 Fez1 CENP-Q PF13094.6 KUM56052.1 - 0.6 10.3 22.1 0.079 13.2 17.2 1.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_MLP1_2 PF07926.12 KUM56052.1 - 0.62 10.1 27.9 0.047 13.7 18.0 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Peptidase_S64 PF08192.11 KUM56052.1 - 0.63 8.5 16.2 0.36 9.3 14.4 1.3 1 1 0 1 1 1 0 Peptidase family S64 CENP-F_leu_zip PF10473.9 KUM56052.1 - 0.81 9.7 29.2 90 3.1 29.2 2.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-H PF05837.12 KUM56052.1 - 1.1 9.7 30.8 0.31 11.4 9.4 3.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FliD_N PF02465.18 KUM56052.1 - 1.1 10.0 25.7 3.8 8.3 7.3 3.2 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus CCDC74_C PF14917.6 KUM56052.1 - 1.2 9.7 18.0 0.84 10.2 4.8 2.6 1 1 1 2 2 2 0 Coiled coil protein 74, C terminal GIT_CC PF16559.5 KUM56052.1 - 1.4 8.8 16.3 3.6 7.5 0.2 3.7 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.12 KUM56052.1 - 1.6 9.4 14.4 0.41 11.3 0.8 3.5 2 1 1 3 3 3 0 SlyX DUF2570 PF10828.8 KUM56052.1 - 1.7 8.5 20.9 0.15 11.9 6.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2570) DUF4201 PF13870.6 KUM56052.1 - 1.9 8.2 27.8 1.8 8.3 7.3 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) KCT2 PF17818.1 KUM56052.1 - 2.1 8.4 7.2 0.78 9.8 3.6 1.9 1 1 1 2 2 2 0 Keratinocyte-associated gene product FAM76 PF16046.5 KUM56052.1 - 2.8 7.2 22.6 4 6.7 22.6 1.2 1 0 0 1 1 1 0 FAM76 protein Prefoldin_2 PF01920.20 KUM56052.1 - 3.1 7.8 27.0 1.3 9.0 14.2 3.2 1 1 2 3 3 3 0 Prefoldin subunit UPF0242 PF06785.11 KUM56052.1 - 3.5 7.7 27.0 25 4.9 26.2 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Lectin_N PF03954.14 KUM56052.1 - 5.2 6.8 19.7 13 5.5 10.0 2.6 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF4200 PF13863.6 KUM56052.1 - 5.3 7.5 31.4 28 5.2 17.7 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF1664 PF07889.12 KUM56052.1 - 5.5 7.0 18.6 1.6 8.8 6.3 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 KUM56052.1 - 6.5 6.9 31.2 0.16 12.0 5.9 3.3 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Jnk-SapK_ap_N PF09744.9 KUM56052.1 - 8 6.7 27.7 5.2e+03 -2.5 27.7 2.2 1 1 0 1 1 0 0 JNK_SAPK-associated protein-1 KxDL PF10241.9 KUM56052.1 - 8 6.8 22.1 0.34 11.2 3.0 3.7 1 1 3 4 4 4 0 Uncharacterized conserved protein DUF4407 PF14362.6 KUM56052.1 - 10 5.4 20.8 2.8 7.2 17.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3723 PF12520.8 KUM56053.1 - 8.2e-112 374.5 0.4 7.1e-62 209.7 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) DUF5340 PF17275.2 KUM56054.1 - 0.061 13.5 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5340) Angiomotin_C PF12240.8 KUM56054.1 - 3.5 7.1 8.9 1.5 8.3 5.9 1.8 1 1 1 2 2 2 0 Angiomotin C terminal Dynamin_N PF00350.23 KUM56056.1 - 7.7e-18 65.1 0.1 2.2e-17 63.6 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KUM56056.1 - 4.2e-13 49.2 0.0 2.2e-11 43.5 0.0 2.4 2 0 0 2 2 2 1 Dynamin central region GED PF02212.18 KUM56056.1 - 0.00023 21.2 0.2 0.0023 18.0 0.0 2.7 2 1 0 2 2 2 1 Dynamin GTPase effector domain SSV1_ORF_D-335 PF07935.11 KUM56056.1 - 0.074 13.4 0.0 58 4.1 0.0 3.2 3 0 0 3 3 3 0 ORF D-335-like protein DUF4413 PF14372.6 KUM56057.1 - 8.7e-05 22.8 0.1 0.00014 22.2 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4413) Arc_C PF18162.1 KUM56057.1 - 0.0082 16.0 0.1 0.16 11.8 0.0 2.2 2 0 0 2 2 2 1 Arc C-lobe COesterase PF00135.28 KUM56058.1 - 5.4e-07 28.9 0.0 5.6e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family MFS_1 PF07690.16 KUM56059.1 - 3.9e-28 98.4 37.0 3.9e-28 98.4 37.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM56059.1 - 0.11 11.3 23.5 0.048 12.5 6.4 2.8 2 2 0 2 2 2 0 Sugar (and other) transporter OATP PF03137.20 KUM56059.1 - 2.2 6.5 16.5 0.26 9.5 0.7 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Alpha-amylase PF00128.24 KUM56060.1 - 1.3e-65 222.2 0.4 1.8e-65 221.7 0.4 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KUM56060.1 - 3.7e-32 110.5 0.1 1.1e-31 109.0 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) CBM_20 PF00686.19 KUM56060.1 - 4.1e-30 103.6 0.2 8.9e-30 102.5 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain SBBP PF06739.11 KUM56060.1 - 0.012 15.6 1.2 0.22 11.6 0.1 3.3 2 0 0 2 2 2 0 Beta-propeller repeat Glyco_hydro_15 PF00723.21 KUM56061.1 - 4.9e-106 355.2 0.4 5.9e-106 354.9 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KUM56061.1 - 8.4e-32 109.0 0.9 2e-31 107.8 0.9 1.7 1 0 0 1 1 1 1 Starch binding domain Fungal_trans PF04082.18 KUM56062.1 - 2.2e-07 30.2 0.0 3.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KUM56065.1 - 1.4e-19 70.6 0.0 5.7e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KUM56065.1 - 5.9e-05 22.3 2.0 0.039 13.0 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein Amino_oxidase PF01593.24 KUM56065.1 - 8.7e-05 22.0 0.0 0.078 12.2 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DUF3112 PF11309.8 KUM56066.1 - 3.2e-10 39.8 6.5 2.6e-06 27.1 0.0 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) Prolactin_RP PF15172.6 KUM56066.1 - 0.11 12.2 0.3 0.22 11.2 0.3 1.5 1 0 0 1 1 1 0 Prolactin-releasing peptide DUF4271 PF14093.6 KUM56066.1 - 0.26 11.2 12.4 0.14 12.1 10.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) DUF2070 PF09843.9 KUM56066.1 - 1.8 6.8 10.4 2.4 6.4 10.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) APH PF01636.23 KUM56069.1 - 6.3e-09 36.1 0.5 2.1e-08 34.4 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family CENP-B_dimeris PF09026.10 KUM56069.1 - 0.00027 21.3 6.2 0.00027 21.3 6.2 3.5 3 1 0 3 3 3 2 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 KUM56069.1 - 0.0054 16.5 7.0 0.0054 16.5 7.0 3.1 3 0 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein Utp14 PF04615.13 KUM56069.1 - 1.2 7.6 14.3 0.092 11.3 1.5 2.3 2 1 0 2 2 2 0 Utp14 protein Ribosomal_S25 PF03297.15 KUM56070.1 - 4.9e-38 129.4 3.1 5.3e-38 129.3 3.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.12 KUM56070.1 - 0.033 13.9 0.1 0.044 13.5 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain MarR_2 PF12802.7 KUM56070.1 - 0.039 13.9 0.1 0.048 13.5 0.1 1.2 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 KUM56070.1 - 0.075 13.4 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_24 PF13412.6 KUM56070.1 - 0.091 12.3 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cyt-b5 PF00173.28 KUM56071.1 - 3.9e-12 46.1 0.0 5.2e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NQR2_RnfD_RnfE PF03116.15 KUM56071.1 - 0.052 13.0 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family DUF473 PF04322.12 KUM56071.1 - 0.17 11.7 0.1 0.27 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF473) EAF PF09816.9 KUM56073.1 - 2.2e-21 76.1 0.2 4.2e-21 75.2 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Cyclin_N PF00134.23 KUM56074.1 - 2.5e-15 56.4 1.3 6.9e-15 54.9 0.6 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KUM56074.1 - 9.3e-05 22.5 0.3 0.0016 18.5 0.0 2.4 2 1 0 2 2 2 1 Cyclin, C-terminal domain Pex24p PF06398.11 KUM56074.1 - 0.0036 16.4 0.0 0.024 13.6 0.0 2.0 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Cyclin_C_2 PF16899.5 KUM56074.1 - 0.034 14.5 0.0 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 Cyclin C-terminal domain TFIIB PF00382.19 KUM56074.1 - 0.63 10.1 4.2 1.7 8.8 0.6 2.6 2 0 0 2 2 2 0 Transcription factor TFIIB repeat AMPK1_CBM PF16561.5 KUM56075.1 - 2.7e-17 62.8 0.9 4.8e-17 61.9 0.9 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase cNMP_binding PF00027.29 KUM56076.1 - 2.3e-40 136.6 0.0 6.6e-21 74.2 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Forkhead PF00250.18 KUM56077.1 - 3.6e-17 62.4 0.0 6.5e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KUM56077.1 - 6.5e-07 29.6 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain CDC45 PF02724.14 KUM56077.1 - 8.1 4.6 9.1 13 3.9 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein 2OG-FeII_Oxy_3 PF13640.6 KUM56078.1 - 5.7e-10 40.0 0.0 1.1e-09 39.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RPN7 PF10602.9 KUM56079.1 - 4.1e-51 173.1 0.1 6.4e-51 172.5 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KUM56079.1 - 1.4e-11 44.8 0.0 1.3e-10 41.7 0.0 2.4 2 0 0 2 2 2 1 PCI domain TPR_16 PF13432.6 KUM56079.1 - 0.21 12.3 6.3 14 6.4 1.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KUM56079.1 - 0.21 11.8 1.6 4.6 7.6 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat p450 PF00067.22 KUM56082.1 - 4.7e-64 216.8 0.0 5.7e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 KUM56083.1 - 4.2e-21 75.5 0.0 6.6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM56083.1 - 3.9e-10 40.3 0.0 9.2e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM56083.1 - 4.4e-08 33.8 0.0 6.7e-07 30.0 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM56083.1 - 1.7e-07 31.8 0.0 3.9e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM56083.1 - 0.0015 18.3 0.0 0.031 14.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KUM56083.1 - 0.022 14.3 0.0 0.054 13.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.9 KUM56083.1 - 0.079 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KUM56083.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 KUM56083.1 - 0.2 11.4 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) adh_short PF00106.25 KUM56084.1 - 4.4e-29 101.3 1.5 8.7e-21 74.3 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM56084.1 - 4.5e-25 88.6 0.6 8.1e-23 81.2 0.6 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM56084.1 - 8.7e-06 25.8 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KUM56084.1 - 0.015 14.7 0.0 0.033 13.6 0.0 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Isochorismatase PF00857.20 KUM56085.1 - 8.1e-44 149.9 0.1 9.2e-44 149.7 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family CobU PF02283.16 KUM56085.1 - 0.052 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF87 PF01935.17 KUM56085.1 - 0.092 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Glyco_hydro_3_C PF01915.22 KUM56086.1 - 1.1e-49 169.1 0.0 1.7e-49 168.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KUM56086.1 - 4.1e-33 115.1 0.0 8e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KUM56086.1 - 2.5e-21 75.6 0.0 4.9e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain UPF0147 PF03685.13 KUM56086.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Cupin_2 PF07883.11 KUM56087.1 - 2.6e-20 71.9 0.7 3.6e-10 39.4 0.2 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KUM56087.1 - 1.9e-18 65.9 1.5 3.6e-15 55.4 0.4 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KUM56087.1 - 8e-06 25.8 0.3 0.035 14.0 0.0 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 KUM56087.1 - 8.8e-05 22.6 0.0 0.00017 21.7 0.0 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like DnaJ PF00226.31 KUM56088.1 - 6.7e-15 55.0 0.7 6.7e-15 55.0 0.7 2.2 3 0 0 3 3 3 1 DnaJ domain PAPS_reduct PF01507.19 KUM56089.1 - 1.2e-24 87.3 0.0 7e-23 81.6 0.0 2.1 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family AA_permease PF00324.21 KUM56090.1 - 1.6e-128 429.3 37.4 1.8e-128 429.2 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM56090.1 - 4.9e-44 150.8 42.0 6.3e-44 150.5 42.0 1.1 1 0 0 1 1 1 1 Amino acid permease DEAD PF00270.29 KUM56091.1 - 4.9e-47 160.0 0.0 8.4e-47 159.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM56091.1 - 9e-24 84.0 0.0 4.7e-23 81.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KUM56091.1 - 4.7e-20 71.6 0.0 1.3e-19 70.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KUM56091.1 - 2.8e-08 34.0 0.0 1e-07 32.1 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RRM_1 PF00076.22 KUM56092.1 - 2e-20 72.3 0.0 1.6e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Serglycin PF04360.12 KUM56092.1 - 0.48 10.4 4.9 1.1 9.2 4.9 1.6 1 0 0 1 1 1 0 Serglycin Ank_2 PF12796.7 KUM56094.1 - 3.4e-39 133.3 1.7 3.1e-17 62.9 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KUM56094.1 - 2.5e-22 78.6 7.3 1e-08 35.3 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM56094.1 - 5.6e-21 72.4 1.9 0.00018 21.6 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KUM56094.1 - 5.4e-20 71.5 8.2 3.3e-07 30.7 0.3 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KUM56094.1 - 4.3e-18 64.9 1.8 0.001 19.4 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat bZIP_1 PF00170.21 KUM56094.1 - 0.076 13.1 7.8 0.15 12.2 7.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KUM56094.1 - 0.1 12.7 8.8 0.22 11.7 8.8 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Cupin_1 PF00190.22 KUM56095.1 - 2.8e-40 137.4 0.3 3.1e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KUM56095.1 - 4.6e-23 80.7 0.7 8.5e-12 44.6 0.2 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KUM56095.1 - 5.5e-07 29.6 0.0 3.5e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.12 KUM56095.1 - 1.8e-06 27.5 0.0 0.04 13.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 KUM56095.1 - 0.0012 18.7 0.0 0.023 14.6 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_6 PF12852.7 KUM56095.1 - 0.0084 15.9 0.1 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Cupin 3-HAO PF06052.12 KUM56095.1 - 0.042 13.5 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase DUF1971 PF09313.11 KUM56095.1 - 0.067 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) Cupin_4 PF08007.12 KUM56095.1 - 0.072 12.5 0.0 0.32 10.4 0.0 1.8 2 0 0 2 2 2 0 Cupin superfamily protein ARD PF03079.14 KUM56095.1 - 0.19 11.9 0.1 0.55 10.4 0.0 1.7 2 0 0 2 2 2 0 ARD/ARD' family Arginase PF00491.21 KUM56096.1 - 2.3e-16 60.1 0.0 2.8e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family Orbi_VP7 PF00897.17 KUM56097.1 - 0.18 10.8 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Orbivirus inner capsid protein VP7 Epimerase PF01370.21 KUM56099.1 - 3.3e-11 43.1 0.1 1.7e-09 37.5 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KUM56099.1 - 6.3e-10 39.2 0.2 9.5e-10 38.7 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KUM56099.1 - 3.2e-07 30.2 0.1 5e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KUM56099.1 - 5.2e-07 30.1 0.1 9.3e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KUM56099.1 - 0.00076 18.6 0.0 0.0022 17.1 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KUM56099.1 - 0.0012 18.0 0.0 0.011 15.0 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KUM56099.1 - 0.0024 17.1 0.1 0.004 16.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DXP_reductoisom PF02670.16 KUM56099.1 - 0.0033 18.1 0.1 0.0053 17.5 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase GDP_Man_Dehyd PF16363.5 KUM56099.1 - 0.014 14.8 0.1 0.43 9.9 0.1 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KUM56099.1 - 0.02 14.0 0.3 0.05 12.7 0.2 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain GFO_IDH_MocA PF01408.22 KUM56099.1 - 0.054 14.3 0.1 0.11 13.3 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold LSM PF01423.22 KUM56101.1 - 1.6e-14 53.3 0.1 2.6e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 LSM domain DNA_pol3_chi PF04364.13 KUM56101.1 - 0.07 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC NUC173 PF08161.12 KUM56102.1 - 8.9e-81 270.4 0.0 1.3e-77 260.1 0.0 3.0 3 0 0 3 3 3 2 NUC173 domain CdiI_2 PF18593.1 KUM56102.1 - 0.022 15.4 0.1 9.6 6.9 0.0 3.3 3 0 0 3 3 3 0 CdiI immunity protein DUF3384 PF11864.8 KUM56102.1 - 0.038 12.9 2.1 42 2.8 0.7 4.3 4 1 1 5 5 5 0 Domain of unknown function (DUF3384) HEAT PF02985.22 KUM56102.1 - 0.098 13.0 1.9 16 6.1 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat DUF5071 PF16804.5 KUM56102.1 - 0.1 12.8 0.1 28 5.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) TFCD_C PF12612.8 KUM56102.1 - 0.11 12.3 0.3 11 5.8 0.0 3.7 4 0 0 4 4 4 0 Tubulin folding cofactor D C terminal Cwf_Cwc_15 PF04889.12 KUM56102.1 - 8.8 6.0 13.6 0.42 10.3 6.8 2.2 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein zf-C2H2_4 PF13894.6 KUM56104.1 - 8.4 7.5 6.4 28 5.9 1.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger AA_permease PF00324.21 KUM56105.1 - 8.3e-77 258.8 22.9 1e-76 258.5 22.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM56105.1 - 7.3e-21 74.5 21.1 8e-21 74.4 21.1 1.0 1 0 0 1 1 1 1 Amino acid permease TMEM213 PF15192.6 KUM56105.1 - 0.072 13.1 0.3 0.27 11.2 0.3 2.0 1 0 0 1 1 1 0 TMEM213 family AA_permease PF00324.21 KUM56106.1 - 9.7e-15 54.1 7.4 1.2e-14 53.9 7.4 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.18 KUM56107.1 - 3.2e-14 52.6 0.4 1.2e-13 50.8 0.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2993 PF11209.8 KUM56107.1 - 0.02 15.2 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2993) Aminotran_3 PF00202.21 KUM56108.1 - 2.2e-87 293.4 0.0 2.6e-87 293.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KUM56108.1 - 0.051 12.7 0.0 0.16 11.1 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II Tho2 PF11262.8 KUM56109.1 - 0.81 8.8 13.0 0.84 8.8 13.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Guanylin PF02058.15 KUM56109.1 - 1 9.9 4.4 4 8.0 4.4 2.0 1 1 0 1 1 1 0 Guanylin precursor Herpes_UL6 PF01763.16 KUM56109.1 - 1.8 7.0 8.6 1.8 7.0 8.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like AAA_23 PF13476.6 KUM56109.1 - 4.4 7.8 12.5 4.9 7.6 12.5 1.1 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 KUM56109.1 - 9.8 5.4 17.4 11 5.2 17.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_hydro_20 PF00728.22 KUM56110.1 - 3.8e-102 342.3 0.8 4.9e-102 341.9 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KUM56110.1 - 3.1e-23 83.0 0.0 5.5e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KUM56110.1 - 3.4e-05 24.6 0.0 6.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DHDPS PF00701.22 KUM56111.1 - 1.1e-51 175.2 0.0 1.4e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF3197 PF11432.8 KUM56111.1 - 0.077 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) Bac_rhodopsin PF01036.18 KUM56113.1 - 2.6e-31 109.0 14.5 3.1e-31 108.7 14.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein UPF0093 PF03653.13 KUM56113.1 - 0.0098 16.1 2.3 0.029 14.6 0.2 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0093) DUF5325 PF17259.2 KUM56113.1 - 0.55 10.2 9.4 3.5 7.6 0.5 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5325) Phage_holin_3_6 PF07332.11 KUM56113.1 - 0.98 9.5 15.2 0.74 9.9 4.1 3.0 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III tRNA-synt_1 PF00133.22 KUM56114.1 - 1.1e-157 525.9 0.0 1.4e-157 525.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KUM56114.1 - 1.2e-20 73.7 0.0 1.8e-12 46.8 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KUM56114.1 - 3.6e-18 66.0 0.3 6.1e-18 65.2 0.3 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.14 KUM56114.1 - 0.0015 18.3 2.3 0.0033 17.3 2.3 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.6 KUM56114.1 - 0.003 17.1 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KUM56114.1 - 0.076 12.4 0.0 6.6 6.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain ABC_tran PF00005.27 KUM56116.1 - 4.6e-33 114.6 0.0 8.3e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KUM56116.1 - 2.5e-25 89.6 21.7 8.5e-24 84.6 6.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KUM56116.1 - 1.3e-07 31.3 0.0 0.00013 21.5 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KUM56116.1 - 0.00072 19.2 0.3 0.0018 18.0 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KUM56116.1 - 0.0059 16.5 0.1 1.8 8.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 KUM56116.1 - 0.009 14.9 0.1 0.05 12.4 0.0 1.9 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 KUM56116.1 - 0.013 15.0 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KUM56116.1 - 0.035 14.0 0.1 0.088 12.7 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KUM56116.1 - 0.049 14.0 0.3 0.18 12.2 0.3 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KUM56116.1 - 0.062 13.6 0.1 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KUM56116.1 - 0.11 12.7 0.1 1.1 9.6 0.1 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 KUM56116.1 - 0.16 11.7 0.3 1.2 8.8 0.0 2.4 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_15 PF13175.6 KUM56116.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ABC_membrane PF00664.23 KUM56117.1 - 2.6e-25 89.6 5.2 3.1e-25 89.4 5.2 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region Aa_trans PF01490.18 KUM56118.1 - 1.1e-37 129.7 28.8 1.3e-37 129.5 28.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ABC_tran PF00005.27 KUM56119.1 - 3.6e-32 111.7 0.0 5.9e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KUM56119.1 - 6.2e-06 25.8 0.0 0.0013 18.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KUM56119.1 - 0.00029 21.1 0.1 0.002 18.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 KUM56119.1 - 0.00052 18.9 0.4 0.021 13.7 0.1 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 KUM56119.1 - 0.00061 19.4 0.2 0.077 12.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KUM56119.1 - 0.0022 17.9 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KUM56119.1 - 0.0048 17.3 0.6 0.015 15.7 0.5 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KUM56119.1 - 0.0075 16.0 0.1 0.065 13.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KUM56119.1 - 0.0077 15.9 0.5 0.018 14.8 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KUM56119.1 - 0.0091 15.8 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KUM56119.1 - 0.011 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KUM56119.1 - 0.015 15.7 0.0 4.6 7.7 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KUM56119.1 - 0.022 15.0 0.3 0.18 12.1 0.3 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 KUM56119.1 - 0.023 14.2 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KUM56119.1 - 0.05 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KUM56119.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Ret2_MD PF18528.1 KUM56119.1 - 0.08 13.3 0.0 0.98 9.8 0.0 2.1 2 0 0 2 2 2 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Zeta_toxin PF06414.12 KUM56119.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Fungal_trans PF04082.18 KUM56120.1 - 6.5e-31 107.3 0.7 1.1e-30 106.6 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH_1 PF00378.20 KUM56121.1 - 1.7e-28 99.6 0.0 2.2e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KUM56121.1 - 2e-14 53.9 0.0 2.2e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Crystallin PF00525.18 KUM56121.1 - 0.12 12.6 0.1 0.56 10.4 0.0 2.1 2 0 0 2 2 2 0 Alpha crystallin A chain, N terminal Hist_deacetyl PF00850.19 KUM56123.1 - 1.4e-49 169.2 0.0 3e-49 168.2 0.0 1.6 1 1 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.11 KUM56123.1 - 0.04 13.8 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 RTP801 C-terminal region AXIN1_TNKS_BD PF16646.5 KUM56124.1 - 0.12 13.3 0.3 0.16 12.9 0.3 1.3 1 0 0 1 1 1 0 Axin-1 tankyrase binding domain Ala_racemase_N PF01168.20 KUM56125.1 - 6.4e-21 75.0 0.0 8.2e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.20 KUM56126.1 - 1.7e-125 419.5 3.8 2.3e-125 419.2 3.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KUM56126.1 - 1.6e-43 147.5 0.0 3.7e-43 146.3 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KUM56126.1 - 1e-16 61.2 0.0 2.7e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain RTP1_C1 PF10363.9 KUM56126.1 - 0.1 12.8 0.4 0.59 10.3 0.1 2.5 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Homeodomain PF00046.29 KUM56128.1 - 9.2e-17 60.7 4.1 1.9e-16 59.6 4.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KUM56128.1 - 0.071 13.0 0.2 0.18 11.7 0.2 1.7 1 0 0 1 1 1 0 Homeobox KN domain Sugar_tr PF00083.24 KUM56129.1 - 5.4e-78 262.9 21.2 6.1e-78 262.7 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM56129.1 - 1.5e-17 63.6 30.3 9.5e-17 60.9 22.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SnoaL_4 PF13577.6 KUM56130.1 - 2.1e-05 24.7 0.5 3.3e-05 24.0 0.5 1.3 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KUM56130.1 - 0.015 15.7 0.2 0.034 14.5 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 KUM56130.1 - 0.078 13.6 0.5 0.12 13.0 0.5 1.5 1 1 0 1 1 1 0 SnoaL-like domain CDC14 PF08045.11 KUM56131.1 - 4.1e-124 413.3 0.0 4.6e-124 413.1 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component PSII_Pbs27 PF13326.6 KUM56131.1 - 0.14 12.5 0.1 0.29 11.4 0.1 1.4 1 0 0 1 1 1 0 Photosystem II Pbs27 polyprenyl_synt PF00348.17 KUM56132.1 - 2.7e-65 220.0 0.0 3.2e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase GST_N_4 PF17172.4 KUM56133.1 - 4.1e-24 85.2 0.1 6.6e-24 84.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KUM56133.1 - 4.4e-19 68.0 0.0 9e-19 67.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KUM56133.1 - 6.4e-14 52.3 0.1 1e-13 51.7 0.1 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 KUM56133.1 - 5.1e-07 30.0 0.2 1.5e-06 28.5 0.1 1.7 1 1 0 2 2 2 1 SAM35, subunit of SAM coomplex GST_C_2 PF13410.6 KUM56133.1 - 0.0037 17.3 0.1 0.007 16.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Methyltransf_25 PF13649.6 KUM56134.1 - 3.5e-07 30.8 0.0 8.9e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM56134.1 - 2.1e-06 28.3 0.1 1.4e-05 25.6 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM56134.1 - 4.7e-06 26.5 0.0 6.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM56134.1 - 1.7e-05 25.5 0.0 3.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM56134.1 - 4.2e-05 23.4 0.0 7.6e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_33 PF10017.9 KUM56134.1 - 0.0065 15.7 0.0 0.014 14.5 0.0 1.5 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_32 PF13679.6 KUM56134.1 - 0.014 15.4 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KUM56134.1 - 0.015 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TehB PF03848.14 KUM56134.1 - 0.025 14.0 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB CheR PF01739.18 KUM56134.1 - 0.034 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain DUF1771 PF08590.10 KUM56135.1 - 2e-25 88.9 5.2 2e-25 88.9 5.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KUM56135.1 - 2.7e-10 40.5 0.3 7.3e-10 39.1 0.3 1.8 1 0 0 1 1 1 1 Smr domain G-alpha PF00503.20 KUM56136.1 - 1.8e-124 415.5 2.1 2.1e-124 415.3 2.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KUM56136.1 - 2.3e-15 56.5 1.6 2.4e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KUM56136.1 - 7.4e-05 22.5 0.0 0.00033 20.4 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KUM56136.1 - 0.0018 17.7 3.4 0.044 13.1 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KUM56136.1 - 0.0081 16.4 0.9 2.4 8.4 0.0 3.2 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KUM56136.1 - 0.014 15.2 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 KUM56136.1 - 0.055 12.6 0.1 0.12 11.5 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 KUM56136.1 - 0.083 12.4 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KUM56136.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KUM56136.1 - 0.14 12.3 0.1 8.9 6.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Copper-fist PF00649.18 KUM56137.1 - 3.9e-18 64.6 0.4 1.1e-17 63.2 0.4 1.9 1 0 0 1 1 1 1 Copper fist DNA binding domain OPT PF03169.15 KUM56138.1 - 1.6e-163 545.7 54.8 1.8e-163 545.5 54.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Transp_cyt_pur PF02133.15 KUM56139.1 - 1.7e-22 79.8 36.8 3.5e-22 78.8 36.8 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin UPF0139 PF03669.13 KUM56139.1 - 0.045 13.6 1.4 0.12 12.3 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) Ank_2 PF12796.7 KUM56140.1 - 7.4e-40 135.4 0.0 1e-14 54.9 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM56140.1 - 1.1e-35 121.5 0.1 5e-08 33.3 0.0 5.8 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM56140.1 - 4.6e-35 119.2 2.3 1.9e-10 40.7 0.1 7.9 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KUM56140.1 - 2.8e-29 100.2 3.5 9.7e-05 22.6 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 KUM56140.1 - 4.4e-29 97.3 1.9 0.0097 16.4 0.1 8.5 9 0 0 9 9 9 7 Ankyrin repeat DUF2183 PF09949.9 KUM56141.1 - 5.4e-21 74.8 0.1 1e-20 73.9 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) GLE1 PF07817.13 KUM56143.1 - 6.3e-48 163.2 0.0 3.2e-47 160.9 0.0 2.0 1 1 0 1 1 1 1 GLE1-like protein Borrelia_P83 PF05262.11 KUM56143.1 - 1.2 7.6 31.3 1.8 7.0 31.3 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF572 PF04502.13 KUM56143.1 - 8.1 6.0 28.9 12 5.4 28.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) UQ_con PF00179.26 KUM56145.1 - 2.5e-35 121.1 0.0 4.2e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KUM56145.1 - 0.0017 18.0 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KUM56145.1 - 0.089 13.1 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 RWD domain DUF4948 PF16306.5 KUM56145.1 - 0.33 10.7 0.0 0.33 10.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4948) RNB PF00773.19 KUM56146.1 - 2.1e-85 286.9 0.0 4.4e-85 285.9 0.0 1.5 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KUM56146.1 - 7.5e-26 90.0 0.0 1.8e-25 88.7 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KUM56146.1 - 2.4e-25 88.6 0.0 7.6e-25 87.1 0.0 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 KUM56146.1 - 0.0002 21.5 0.0 0.019 15.1 0.0 2.7 2 0 0 2 2 2 1 Cold shock domain Rrp44_CSD1 PF17216.3 KUM56146.1 - 0.00024 20.9 0.0 0.00058 19.6 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain MIP PF00230.20 KUM56147.1 - 4.5e-45 154.1 10.9 5.8e-45 153.8 10.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein SKG6 PF08693.10 KUM56148.1 - 6.1e-07 28.7 0.0 6.1e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Mid2 PF04478.12 KUM56148.1 - 0.0085 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Abhydrolase_3 PF07859.13 KUM56149.1 - 1.1e-42 146.3 0.0 1.5e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KUM56149.1 - 2.5e-06 26.7 0.3 1e-05 24.6 0.3 1.8 1 1 0 1 1 1 1 Carboxylesterase family DUF2974 PF11187.8 KUM56149.1 - 0.038 13.5 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.21 KUM56149.1 - 0.12 11.9 0.0 3.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family tRNA-synt_2 PF00152.20 KUM56150.1 - 1.1e-72 244.8 0.0 1.7e-72 244.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KUM56150.1 - 2.5e-17 62.8 0.0 3.6e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 KUM56150.1 - 0.00036 20.5 0.0 0.00074 19.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KUM56150.1 - 0.014 14.9 0.1 5.5 6.4 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) MCM_N PF14551.6 KUM56150.1 - 0.05 14.2 0.0 0.15 12.7 0.0 1.8 1 0 0 1 1 1 0 MCM N-terminal domain GerPC PF10737.9 KUM56150.1 - 0.11 12.6 0.2 0.39 10.8 0.0 2.0 3 0 0 3 3 3 0 Spore germination protein GerPC Pga1 PF10333.9 KUM56151.1 - 0.0017 18.2 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Tubulin PF00091.25 KUM56152.1 - 1.8e-66 224.1 0.0 2.7e-66 223.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KUM56152.1 - 1.2e-49 167.7 0.0 2.2e-49 166.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KUM56152.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain MFS_1 PF07690.16 KUM56154.1 - 2e-21 76.3 71.4 4.9e-18 65.2 45.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily VIT1 PF01988.19 KUM56154.1 - 0.062 13.2 0.2 0.062 13.2 0.2 3.6 2 1 0 3 3 3 0 VIT family AA_permease PF00324.21 KUM56155.1 - 3.3e-128 428.3 47.9 4.1e-128 428.0 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM56155.1 - 2.4e-30 105.7 52.6 2.9e-30 105.5 52.6 1.0 1 0 0 1 1 1 1 Amino acid permease Acyl-CoA_dh_M PF02770.19 KUM56156.1 - 5e-18 65.1 0.1 7.8e-18 64.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KUM56156.1 - 5.3e-17 62.4 0.8 9.3e-17 61.6 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KUM56156.1 - 6.1e-07 29.8 0.3 1.3e-06 28.8 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KUM56156.1 - 0.00096 18.9 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal p450 PF00067.22 KUM56157.1 - 1.2e-52 179.2 0.1 1.7e-52 178.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 IFT81_CH PF18383.1 KUM56157.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Intraflagellar transport 81 calponin homology domain WD40 PF00400.32 KUM56158.1 - 2.7e-42 141.9 12.4 1.9e-06 28.5 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 KUM56158.1 - 2.3e-13 49.8 0.3 5.2e-13 48.7 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KUM56158.1 - 2e-10 40.2 0.8 5.8e-10 38.8 0.1 2.1 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 KUM56158.1 - 1.3e-09 37.3 8.7 0.055 12.1 0.2 5.2 2 2 2 5 5 5 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KUM56158.1 - 0.00032 20.9 0.3 0.85 10.0 0.0 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KUM56158.1 - 0.002 18.0 0.2 0.026 14.4 0.0 2.8 3 0 0 3 3 3 1 F-box PhoPQ_related PF10142.9 KUM56158.1 - 0.12 11.0 0.2 0.48 9.0 0.1 1.8 1 1 1 2 2 2 0 PhoPQ-activated pathogenicity-related protein CBM39 PF15886.5 KUM56159.1 - 0.064 13.2 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 32) DUF3915 PF13054.6 KUM56159.1 - 0.11 12.5 1.2 0.12 12.4 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 KUM56159.1 - 1.2 7.3 2.6 1.3 7.2 2.6 1.0 1 0 0 1 1 1 0 Atrophin-1 family Methyltransf_2 PF00891.18 KUM56160.1 - 0.0001 21.7 0.5 0.00032 20.1 0.1 1.7 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_2 PF00891.18 KUM56161.1 - 3.1e-13 49.5 0.0 3.5e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_33 PF10017.9 KUM56161.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.4 1 1 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent SMC_N PF02463.19 KUM56162.1 - 2.6e-73 246.1 0.1 4.3e-73 245.4 0.1 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KUM56162.1 - 6.1e-32 110.4 0.4 5.2e-31 107.4 0.0 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KUM56162.1 - 1.2e-18 68.3 4.3 1.2e-18 68.3 4.3 6.9 2 2 2 4 4 2 1 AAA domain AAA_21 PF13304.6 KUM56162.1 - 8.7e-17 61.9 10.0 9.6e-11 42.0 0.0 3.4 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KUM56162.1 - 2.2e-13 50.7 47.4 2.8e-08 33.9 18.3 4.6 2 2 1 3 3 3 2 AAA ATPase domain APG6_N PF17675.1 KUM56162.1 - 0.0013 19.2 8.1 0.0013 19.2 8.1 8.3 2 2 6 9 9 9 2 Apg6 coiled-coil region XH PF03469.14 KUM56162.1 - 0.0024 17.8 7.4 0.011 15.6 0.6 3.5 2 0 0 2 2 2 1 XH domain TMF_TATA_bd PF12325.8 KUM56162.1 - 0.005 17.0 2.1 0.005 17.0 2.1 9.1 6 3 3 9 9 9 2 TATA element modulatory factor 1 TATA binding AAA_29 PF13555.6 KUM56162.1 - 0.0053 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4201 PF13870.6 KUM56162.1 - 0.0066 16.2 10.7 0.0066 16.2 10.7 7.5 4 1 2 7 7 7 2 Domain of unknown function (DUF4201) FtsK_SpoIIIE PF01580.18 KUM56162.1 - 0.015 14.7 1.1 0.14 11.5 0.0 2.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 KUM56162.1 - 2.9 7.9 0.0 2.9 7.9 0.0 6.3 3 2 4 7 7 6 0 Helicase HerA, central domain Spc7 PF08317.11 KUM56162.1 - 5.3 5.8 102.5 0.026 13.4 19.2 6.8 2 2 4 6 6 6 0 Spc7 kinetochore protein RIO1 PF01163.22 KUM56163.1 - 3.8e-72 241.9 0.1 3.8e-72 241.9 0.1 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KUM56163.1 - 0.0021 18.0 0.0 0.86 9.5 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KUM56163.1 - 0.023 14.1 0.2 0.37 10.1 0.2 2.2 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APG17 PF04108.12 KUM56164.1 - 2.9e-130 435.0 0.6 3.4e-130 434.7 0.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 HD_2 PF12917.7 KUM56164.1 - 0.0037 17.0 0.1 0.49 10.1 0.0 2.4 2 0 0 2 2 2 2 HD containing hydrolase-like enzyme HR1 PF02185.16 KUM56164.1 - 0.084 13.0 1.9 0.21 11.7 0.2 2.4 2 0 0 2 2 2 0 Hr1 repeat Apt1 PF10351.9 KUM56164.1 - 0.29 10.0 4.6 0.2 10.5 0.1 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF2125 PF09898.9 KUM56164.1 - 0.37 10.4 2.9 0.63 9.6 2.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2125) HAUS-augmin3 PF14932.6 KUM56164.1 - 1.6 8.3 4.5 21 4.6 0.1 3.1 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 5_nucleotid_C PF02872.18 KUM56166.1 - 0.0013 18.9 0.0 0.003 17.8 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KUM56166.1 - 0.15 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase FA_hydroxylase PF04116.13 KUM56167.1 - 2.2e-26 92.8 18.1 4e-26 91.9 18.1 1.4 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily p450 PF00067.22 KUM56168.1 - 5.7e-65 219.9 0.0 6.8e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_12 PF13424.6 KUM56169.1 - 1.7e-32 111.6 3.3 1.4e-06 28.5 0.0 6.8 2 1 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 KUM56169.1 - 2.2e-28 97.3 0.0 0.0033 17.2 0.0 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat NB-ARC PF00931.22 KUM56169.1 - 3.4e-06 26.4 0.0 1.7e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.6 KUM56169.1 - 8.5e-05 23.0 0.6 9 6.9 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KUM56169.1 - 0.00032 20.2 2.6 1.5 8.1 0.0 3.3 1 1 2 3 3 3 2 MalT-like TPR region DUF676 PF05057.14 KUM56169.1 - 0.0021 17.6 0.1 0.0049 16.4 0.1 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_8 PF13181.6 KUM56169.1 - 0.079 13.2 0.4 1e+02 3.5 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.6 KUM56169.1 - 0.1 13.0 1.0 5.1 7.5 0.0 2.8 1 1 1 2 2 2 0 AAA ATPase domain PS-DH PF14765.6 KUM56170.1 - 7.8e-66 222.3 0.0 1.3e-65 221.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KUM56170.1 - 8.1e-57 192.0 0.5 2.5e-56 190.5 0.5 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KUM56170.1 - 2e-48 165.5 0.0 3.4e-48 164.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KAsynt_C_assoc PF16197.5 KUM56170.1 - 4.1e-16 59.4 0.0 5.5e-12 46.1 0.0 3.5 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KUM56170.1 - 1.4e-13 51.0 0.0 4.3e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KUM56170.1 - 1.9e-11 43.8 2.1 1.3e-10 41.1 0.2 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_12 PF08242.12 KUM56170.1 - 3.2e-11 43.9 0.0 8.9e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM56170.1 - 1.7e-10 41.0 0.0 5.7e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KUM56170.1 - 6.3e-08 32.5 1.5 1e-07 31.8 0.2 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KUM56170.1 - 1.1e-07 32.1 0.0 2.6e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 KUM56170.1 - 0.00015 21.6 0.0 0.00043 20.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM56170.1 - 0.00021 21.9 0.0 0.0011 19.6 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM56170.1 - 0.00026 21.7 0.0 0.00099 19.8 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 KUM56170.1 - 0.0077 16.0 7.4 0.18 11.5 2.3 3.8 3 1 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis UDPG_MGDP_dh_C PF03720.15 KUM56170.1 - 0.056 13.9 0.1 0.18 12.2 0.1 1.9 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Ubie_methyltran PF01209.18 KUM56170.1 - 0.15 11.4 0.0 0.41 9.9 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family ketoacyl-synt PF00109.26 KUM56171.1 - 1.1e-72 244.6 0.0 1.4e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KUM56171.1 - 3.5e-20 72.2 0.0 7e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 KUM56171.1 - 0.00041 20.1 0.4 0.00083 19.2 0.4 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 KUM56171.1 - 0.0048 16.3 0.1 0.0077 15.6 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain GMC_oxred_N PF00732.19 KUM56172.1 - 1.8e-12 47.3 0.0 2.4e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DEAD PF00270.29 KUM56173.1 - 3.8e-49 166.8 0.0 3.7e-48 163.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM56173.1 - 1.6e-30 105.7 0.0 5.1e-30 104.1 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM56173.1 - 0.0013 18.8 0.0 0.0041 17.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KUM56173.1 - 0.0063 15.8 0.2 0.0095 15.2 0.2 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 KUM56173.1 - 0.0075 16.6 0.0 0.55 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF5335 PF17269.2 KUM56173.1 - 0.018 14.9 0.1 0.034 14.0 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) UTP25 PF06862.12 KUM56173.1 - 0.021 13.6 0.1 1.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF2443 PF10398.9 KUM56173.1 - 0.15 12.1 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) AAA_22 PF13401.6 KUM56173.1 - 0.38 11.0 2.5 33 4.7 0.0 3.5 3 1 0 4 4 4 0 AAA domain zf-C2H2 PF00096.26 KUM56175.1 - 0.2 12.2 0.2 0.37 11.4 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3987 PF13148.6 KUM56175.1 - 6.1 5.7 6.9 9.5 5.1 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) adh_short_C2 PF13561.6 KUM56178.1 - 3.3e-53 180.6 3.8 6.5e-53 179.7 3.8 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM56178.1 - 1.6e-34 119.1 4.0 8.5e-34 116.7 4.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM56178.1 - 6.8e-07 29.4 4.2 1.6e-05 24.9 4.2 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM56178.1 - 0.0022 17.5 0.4 0.098 12.1 0.1 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KUM56178.1 - 0.0076 15.6 0.4 0.023 14.1 0.2 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KUM56178.1 - 0.048 14.2 1.2 0.093 13.3 1.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent STALD PF18185.1 KUM56178.1 - 0.15 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family 3HCDH_N PF02737.18 KUM56178.1 - 0.18 11.7 1.0 0.29 11.0 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Voldacs PF03517.13 KUM56181.1 - 3.9e-25 88.6 0.5 3.9e-25 88.6 0.5 2.1 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling NAD_binding_10 PF13460.6 KUM56182.1 - 2e-05 24.5 0.0 2.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KUM56182.1 - 0.0034 16.4 0.0 0.0045 16.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KUM56182.1 - 0.0057 15.8 0.1 0.25 10.5 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein DapB_N PF01113.20 KUM56182.1 - 0.1 12.7 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 KUM56182.1 - 0.11 11.7 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KUM56182.1 - 0.2 11.1 0.1 0.54 9.7 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Dioxygenase_C PF00775.21 KUM56184.1 - 1.4e-40 138.6 0.0 1.9e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KUM56184.1 - 4.9e-24 84.0 0.0 8.4e-24 83.2 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CSS-motif PF12792.7 KUM56184.1 - 0.11 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 CSS motif domain associated with EAL CarboxypepD_reg PF13620.6 KUM56184.1 - 0.16 12.3 0.0 0.66 10.3 0.0 2.0 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Ring_hydroxyl_A PF00848.19 KUM56185.1 - 1.3e-19 71.0 1.6 2e-11 44.3 1.0 2.3 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KUM56185.1 - 8.8e-15 54.4 0.0 1.8e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FMN_bind_2 PF04299.12 KUM56186.1 - 3e-56 189.8 0.1 3.4e-56 189.5 0.1 1.0 1 0 0 1 1 1 1 Putative FMN-binding domain Plasmodium_Vir PF05795.11 KUM56187.1 - 0.022 14.2 0.1 0.022 14.2 0.1 2.2 1 1 0 2 2 2 0 Plasmodium vivax Vir protein ABC2_membrane_5 PF13346.6 KUM56187.1 - 0.086 12.4 0.3 0.13 11.8 0.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Herpes_pp38 PF04846.13 KUM56187.1 - 0.16 11.9 0.2 0.31 11.0 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein HemY_N PF07219.13 KUM56187.1 - 1.8 8.8 5.8 0.33 11.2 1.0 2.2 2 0 0 2 2 2 0 HemY protein N-terminus Cwf_Cwc_15 PF04889.12 KUM56187.1 - 9.3 5.9 8.5 2 8.1 4.9 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_lambd_f PF10391.9 KUM56189.1 - 9.7e-22 76.6 0.8 2.1e-21 75.5 0.8 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KUM56189.1 - 3.8e-21 75.0 0.5 3.2e-20 72.1 0.4 2.5 3 0 0 3 3 3 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KUM56189.1 - 1e-15 57.9 0.3 4e-15 56.0 0.3 2.0 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KUM56189.1 - 6.6e-09 36.0 0.0 3.4e-08 33.7 0.1 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KUM56189.1 - 0.00023 21.7 0.0 0.0031 18.1 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain THRAP3_BCLAF1 PF15440.6 KUM56189.1 - 0.33 9.9 7.5 10 5.0 0.0 2.1 2 0 0 2 2 2 0 THRAP3/BCLAF1 family PhoLip_ATPase_C PF16212.5 KUM56190.1 - 3.5e-80 269.4 18.9 3.5e-80 269.4 18.9 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KUM56190.1 - 9.4e-26 89.3 10.8 3e-25 87.7 10.8 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KUM56190.1 - 7.3e-12 46.0 1.1 6.1e-07 29.9 0.1 3.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KUM56190.1 - 7.3e-11 42.0 0.0 2.5e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KUM56190.1 - 5.9e-05 22.7 1.2 7.9e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KUM56190.1 - 0.0055 16.5 0.1 0.02 14.7 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RNase_PH PF01138.21 KUM56191.1 - 3.5e-17 63.2 0.0 5.5e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KUM56191.1 - 1.2e-06 28.4 0.0 3.1e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.12 KUM56192.1 - 7.5e-83 278.1 18.1 9.4e-83 277.7 18.1 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein PA26 PF04636.13 KUM56192.1 - 0.86 8.4 3.9 0.97 8.3 3.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SAPS PF04499.15 KUM56192.1 - 7.2 5.3 9.4 8.3 5.1 9.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SAM_2 PF07647.17 KUM56193.1 - 0.026 14.6 0.0 7 6.8 0.0 2.3 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Josephin PF02099.17 KUM56193.1 - 0.05 13.7 0.1 0.37 10.9 0.2 1.8 1 1 1 2 2 2 0 Josephin Baculo_PEP_N PF04512.12 KUM56193.1 - 0.13 12.5 0.0 15 5.9 0.0 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, N terminus HU-CCDC81_bac_1 PF18174.1 KUM56194.1 - 0.2 11.6 9.1 29 4.6 0.1 4.6 2 1 3 5 5 5 0 CCDC81-like prokaryotic HU domain 1 AFP PF02420.15 KUM56195.1 - 0.029 14.7 2.8 1.3e+02 3.4 0.1 4.3 4 0 0 4 4 4 0 Insect antifreeze protein repeat DUF43 PF01861.16 KUM56195.1 - 0.056 12.7 0.1 0.72 9.0 0.1 2.1 2 0 0 2 2 2 0 Branched-chain polyamine synthase A C-terminal domain Acetyltransf_10 PF13673.7 KUM56196.1 - 5.4e-09 36.1 0.0 1.8e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM56196.1 - 8.7e-05 22.7 0.1 0.00013 22.2 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KUM56196.1 - 0.00013 22.3 0.0 0.00023 21.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KUM56199.1 - 7.8e-42 143.5 54.2 8.3e-42 143.4 50.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM56199.1 - 2.5e-12 46.0 24.4 3.4e-12 45.6 24.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM56199.1 - 5.6e-08 32.1 4.8 5.6e-08 32.1 4.8 3.5 4 0 0 4 4 4 1 Sugar (and other) transporter DUF3377 PF11857.8 KUM56199.1 - 0.93 9.5 2.2 7.1 6.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Colicin_K PF17500.2 KUM56200.1 - 0.044 14.3 2.0 1.1 9.9 0.1 2.4 2 0 0 2 2 2 0 Colicin-K Phage_Coat_Gp8 PF05371.12 KUM56200.1 - 0.57 10.0 5.6 2.7 7.8 0.3 2.8 2 0 0 2 2 2 0 Phage major coat protein, Gp8 AA_permease_2 PF13520.6 KUM56201.1 - 2.7e-44 151.7 50.3 3.4e-44 151.4 50.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM56201.1 - 4.3e-20 71.8 47.7 1.2e-19 70.3 47.7 1.5 1 1 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.24 KUM56202.1 - 1.1e-101 340.9 35.9 1.3e-101 340.7 35.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM56202.1 - 2.3e-29 102.4 36.0 2.3e-29 102.4 36.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 KUM56203.1 - 1.2e-08 35.1 0.0 2.9e-08 33.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KUM56203.1 - 2.7e-08 33.8 0.0 3.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KUM56203.1 - 3.1e-08 33.9 0.0 4.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KUM56203.1 - 0.079 13.0 0.0 0.99 9.5 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.6 KUM56205.1 - 7.3e-49 166.7 56.6 8.9e-49 166.5 56.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM56205.1 - 1.5e-18 66.7 47.7 1.8e-18 66.4 47.7 1.0 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_2 PF00797.17 KUM56206.1 - 4.8e-44 150.9 0.0 7.9e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase DUF2464 PF10240.9 KUM56206.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Multivesicular body subunit 12 zf-met2 PF12907.7 KUM56208.1 - 2.1e-17 63.0 0.5 3.5e-17 62.3 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KUM56208.1 - 1.8e-06 28.7 13.0 3.2e-06 27.9 13.0 1.4 1 0 0 1 1 1 1 4F5 protein family Glyco_hydro_72 PF03198.14 KUM56209.1 - 4.6e-125 417.0 4.0 6.6e-125 416.5 4.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KUM56209.1 - 2.2e-25 89.1 8.4 5.1e-25 87.9 8.4 1.7 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 KUM56209.1 - 0.0017 17.9 0.2 0.015 14.7 0.2 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) adh_short_C2 PF13561.6 KUM56210.1 - 6.9e-46 156.7 0.0 2.8e-45 154.7 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM56210.1 - 6.4e-25 87.8 0.0 3.1e-24 85.5 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM56210.1 - 2.1e-06 27.8 0.1 4.8e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KUM56210.1 - 0.0024 17.4 0.0 0.13 11.7 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Gly_transf_sug PF04488.15 KUM56211.1 - 4.8e-10 39.9 0.0 8.2e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif CAP_N PF01213.19 KUM56211.1 - 0.023 14.2 5.0 0.023 14.2 5.0 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal TolA_bind_tri PF16331.5 KUM56212.1 - 0.018 15.1 4.7 0.056 13.5 4.7 1.9 1 0 0 1 1 1 0 TolA binding protein trimerisation ArAE_2_N PF10337.9 KUM56212.1 - 0.036 13.1 0.1 0.068 12.2 0.1 1.4 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Golgin_A5 PF09787.9 KUM56212.1 - 0.05 13.1 5.5 0.32 10.4 0.2 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 TACC_C PF05010.14 KUM56212.1 - 0.1 12.4 6.7 0.45 10.3 0.7 2.2 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal YfcL PF08891.11 KUM56212.1 - 0.48 10.8 2.1 25 5.3 0.0 2.8 3 0 0 3 3 3 0 YfcL protein SLAM PF06214.11 KUM56213.1 - 0.17 11.9 0.1 0.19 11.8 0.1 1.1 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein DAO PF01266.24 KUM56214.1 - 1.5e-41 143.2 0.0 1.7e-41 143.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KUM56214.1 - 8.3e-06 25.9 0.0 2.1e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KUM56214.1 - 6.4e-05 22.2 0.0 0.039 13.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KUM56214.1 - 0.00019 20.8 0.0 0.045 13.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KUM56214.1 - 0.0012 18.1 0.3 0.033 13.3 0.0 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KUM56214.1 - 0.0016 18.5 0.5 0.94 9.4 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding Glu_dehyd_C PF16912.5 KUM56214.1 - 0.0049 16.4 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus FAD_binding_3 PF01494.19 KUM56214.1 - 0.0091 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KUM56214.1 - 0.015 15.8 0.0 0.037 14.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM56214.1 - 0.02 14.2 0.0 0.049 12.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KUM56214.1 - 0.034 14.2 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KUM56214.1 - 0.045 14.0 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 KUM56214.1 - 0.18 11.0 0.2 0.41 9.9 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Arrestin_C PF02752.22 KUM56217.1 - 2.9e-20 73.1 0.0 9.2e-20 71.5 0.1 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KUM56217.1 - 3.5e-11 43.4 0.0 5.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KUM56217.1 - 0.0045 16.7 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Condensation PF00668.20 KUM56218.1 - 5.3e-49 167.1 0.0 6.9e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Condensation domain Condensation PF00668.20 KUM56219.1 - 9.6e-41 139.9 0.0 1.5e-40 139.3 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KUM56219.1 - 6.4e-09 36.0 0.0 1.3e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF2138 PF09909.9 KUM56219.1 - 0.17 10.2 0.0 0.25 9.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) NCA2 PF08637.10 KUM56220.1 - 8.4e-70 235.2 0.0 1.5e-69 234.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Activator-TraM PF11657.8 KUM56221.1 - 0.02 14.7 0.4 0.035 13.9 0.4 1.3 1 0 0 1 1 1 0 Transcriptional activator TraM DUF1981 PF09324.10 KUM56222.1 - 0.15 11.9 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) TMF_DNA_bd PF12329.8 KUM56223.1 - 0.0016 18.4 0.8 0.0024 17.8 0.2 1.6 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding FTA4 PF13093.6 KUM56223.1 - 0.018 15.0 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 XhlA PF10779.9 KUM56223.1 - 0.019 15.1 0.1 0.034 14.3 0.1 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Prefoldin_2 PF01920.20 KUM56223.1 - 0.039 13.9 0.3 0.064 13.2 0.3 1.3 1 0 0 1 1 1 0 Prefoldin subunit NPV_P10 PF05531.12 KUM56223.1 - 0.062 13.8 0.4 0.31 11.5 0.1 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4795 PF16043.5 KUM56223.1 - 0.067 12.8 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Med9 PF07544.13 KUM56223.1 - 0.07 13.2 0.2 0.15 12.2 0.1 1.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF3450 PF11932.8 KUM56223.1 - 0.072 12.4 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Lebercilin PF15619.6 KUM56223.1 - 0.088 12.5 0.2 0.12 12.0 0.2 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Pox_A_type_inc PF04508.12 KUM56223.1 - 0.12 12.2 0.4 7.7 6.5 0.1 2.3 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat DUF4988 PF16378.5 KUM56223.1 - 0.16 11.6 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function RmlD_sub_bind PF04321.17 KUM56225.1 - 2e-56 191.2 0.0 2.6e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KUM56225.1 - 6.7e-24 84.7 0.0 1.3e-23 83.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KUM56225.1 - 2.1e-12 46.8 0.2 2.6e-08 33.3 0.0 3.1 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KUM56225.1 - 6.6e-12 45.0 0.2 1.2e-10 40.9 0.2 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KUM56225.1 - 2.3e-11 43.4 0.1 2.9e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KUM56225.1 - 1.9e-09 37.4 0.1 1.9e-08 34.1 0.1 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase CNPase PF05881.12 KUM56227.1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) PH PF00169.29 KUM56229.1 - 5.5e-06 26.8 1.9 1.5e-05 25.4 1.5 1.9 2 0 0 2 2 2 1 PH domain RA PF00788.23 KUM56229.1 - 0.00033 21.2 0.0 0.0011 19.5 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain TUG-UBL1 PF11470.8 KUM56229.1 - 0.0065 16.7 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain PH_11 PF15413.6 KUM56229.1 - 0.41 11.1 1.9 1.1 9.7 1.9 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain FAD-oxidase_C PF02913.19 KUM56230.1 - 4.7e-60 203.3 0.0 7.6e-60 202.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KUM56230.1 - 5.5e-36 123.4 0.4 1e-35 122.5 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain LemA PF04011.12 KUM56230.1 - 0.12 12.2 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 LemA family Pkinase PF00069.25 KUM56231.1 - 1.6e-69 234.2 0.0 2.1e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM56231.1 - 8.1e-47 159.7 0.0 1.2e-46 159.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KUM56231.1 - 5e-05 22.3 0.0 9.3e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KUM56231.1 - 0.0005 19.5 0.0 0.004 16.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like MFS_1 PF07690.16 KUM56232.1 - 6.9e-29 100.9 31.7 6.9e-29 100.9 31.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM56232.1 - 1.1e-08 34.4 14.8 1.1e-08 34.4 14.8 2.8 3 1 0 3 3 3 2 Sugar (and other) transporter Senescence PF06911.12 KUM56233.1 - 8.4e-54 182.7 5.6 1.2e-53 182.1 5.6 1.3 1 0 0 1 1 1 1 Senescence-associated protein DUF3082 PF11282.8 KUM56233.1 - 0.0047 17.1 0.1 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3082) SIMPL PF04402.14 KUM56234.1 - 1.7e-30 107.0 0.0 1.9e-30 106.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Fungal_trans PF04082.18 KUM56235.1 - 8.2e-16 57.8 0.0 1.1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KUM56236.1 - 6.6e-72 242.7 0.0 1.6e-71 241.4 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain DUF3347 PF11827.8 KUM56236.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Pyr_redox PF00070.27 KUM56236.1 - 0.016 15.8 0.0 0.65 10.6 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM56236.1 - 0.022 14.0 0.4 0.31 10.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM56236.1 - 0.047 12.9 0.0 0.23 10.7 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM56236.1 - 0.079 13.2 0.0 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain gag_pre-integrs PF13976.6 KUM56237.1 - 4.6e-06 26.4 0.1 1.4e-05 24.8 0.1 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 KUM56237.1 - 0.00014 22.0 0.0 0.00049 20.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 KUM56237.1 - 0.004 16.8 0.2 0.019 14.6 0.0 2.1 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type NAD_binding_2 PF03446.15 KUM56238.1 - 1.1e-20 74.4 0.1 1.8e-20 73.7 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KUM56238.1 - 1.5e-05 25.2 0.0 2.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase His_Phos_1 PF00300.22 KUM56239.1 - 2.7e-14 53.3 0.0 1.6e-08 34.5 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) PD40 PF07676.12 KUM56241.1 - 1.2e-44 149.4 22.8 1.6e-07 31.1 0.5 10.1 10 0 0 10 10 10 8 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 KUM56241.1 - 2.4e-10 39.7 10.0 0.011 14.6 0.3 6.6 5 2 2 7 7 7 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3748 PF12566.8 KUM56241.1 - 0.00036 20.5 3.0 1.6 8.7 0.0 5.2 6 1 0 6 6 6 1 Protein of unknown function (DUF3748) WD40 PF00400.32 KUM56241.1 - 0.0011 19.8 8.9 4.5 8.3 0.0 6.8 6 2 1 7 7 7 1 WD domain, G-beta repeat MFS_1 PF07690.16 KUM56242.1 - 3.1e-21 75.7 56.4 3.1e-21 75.7 56.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peroxidase_2 PF01328.17 KUM56243.1 - 4.6e-30 105.5 0.0 6.7e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 DUF829 PF05705.14 KUM56244.1 - 1.5e-62 211.6 0.0 1.8e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.7 KUM56244.1 - 0.016 15.8 0.1 0.026 15.1 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 KUM56244.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family CN_hydrolase PF00795.22 KUM56245.1 - 8.9e-32 110.5 0.0 1.1e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LysR_substrate PF03466.20 KUM56245.1 - 0.023 14.0 0.0 0.55 9.6 0.0 2.6 3 0 0 3 3 3 0 LysR substrate binding domain HlyIII PF03006.20 KUM56246.1 - 1.8e-20 73.6 9.6 2.4e-20 73.2 9.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related Prok-E2_C PF14459.6 KUM56246.1 - 0.099 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family C CRCB PF02537.15 KUM56246.1 - 0.69 10.3 5.2 1.2 9.5 5.0 1.5 1 1 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) Lipoxygenase PF00305.19 KUM56247.1 - 8.8e-18 64.1 0.4 1.5e-17 63.3 0.1 1.6 2 0 0 2 2 2 1 Lipoxygenase GGACT PF06094.12 KUM56248.1 - 6.7e-15 55.8 0.5 8.6e-15 55.4 0.5 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Aldedh PF00171.22 KUM56249.1 - 2.8e-184 612.9 0.6 3.2e-184 612.8 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TTL PF03133.15 KUM56250.1 - 0.017 14.3 0.0 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family HNH_5 PF14279.6 KUM56250.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease FAD_binding_3 PF01494.19 KUM56251.1 - 5.1e-15 55.6 1.5 3.5e-11 42.9 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KUM56251.1 - 5.9e-08 32.8 0.4 1.9e-07 31.2 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM56251.1 - 1.1e-05 24.9 1.3 3.5e-05 23.2 1.3 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KUM56251.1 - 1.1e-05 24.7 0.2 1.5e-05 24.3 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KUM56251.1 - 1.4e-05 24.8 5.3 1.7e-05 24.6 4.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KUM56251.1 - 2e-05 23.9 2.1 0.00047 19.4 1.5 2.1 1 1 1 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 KUM56251.1 - 0.0019 17.5 0.1 0.027 13.8 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KUM56251.1 - 0.002 17.5 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KUM56251.1 - 0.0023 18.5 1.4 0.0068 16.9 1.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KUM56251.1 - 0.0096 15.0 1.6 0.0096 15.0 1.6 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Rossmann-like PF10727.9 KUM56251.1 - 0.03 14.2 0.6 0.072 13.0 0.6 1.6 1 0 0 1 1 1 0 Rossmann-like domain HI0933_like PF03486.14 KUM56251.1 - 0.057 12.1 1.8 0.083 11.6 1.8 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 KUM56251.1 - 0.085 12.7 1.8 0.16 11.8 1.8 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KUM56251.1 - 0.13 12.4 0.2 0.29 11.3 0.2 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Trp_halogenase PF04820.14 KUM56251.1 - 0.15 10.9 5.6 1.6 7.4 1.8 2.8 2 1 0 3 3 3 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KUM56251.1 - 0.26 10.5 1.0 0.6 9.3 1.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GFO_IDH_MocA PF01408.22 KUM56253.1 - 4.5e-23 82.3 0.1 7.8e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KUM56253.1 - 0.0015 18.5 0.1 0.0026 17.7 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.15 KUM56253.1 - 0.044 13.9 0.0 0.089 13.0 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KUM56253.1 - 0.11 13.1 0.0 0.25 12.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AAA_12 PF13087.6 KUM56254.1 - 1e-07 31.8 0.0 1.3e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain PHY PF00360.20 KUM56254.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Phytochrome region Uma2 PF05685.12 KUM56256.1 - 0.00015 21.3 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 Putative restriction endonuclease PIG-Y PF15159.6 KUM56257.1 - 7.5e-23 81.2 8.1 1.1e-22 80.7 8.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 KUM56257.1 - 0.022 15.3 1.6 4.2 8.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) 4HBT_3 PF13622.6 KUM56260.1 - 1.5e-28 100.7 0.6 2.9e-28 99.8 0.6 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily DUF4082 PF13313.6 KUM56260.1 - 0.012 15.7 0.1 0.027 14.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) DMSP_lyase PF16867.5 KUM56262.1 - 0.014 15.1 0.4 0.034 13.8 0.4 1.6 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase DUF2046 PF09755.9 KUM56262.1 - 0.021 14.1 2.7 0.021 14.1 0.5 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Atg14 PF10186.9 KUM56262.1 - 0.054 12.6 1.8 0.056 12.5 0.3 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_2 PF07716.15 KUM56262.1 - 9 6.5 9.4 0.4 10.8 0.4 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Sec62 PF03839.16 KUM56263.1 - 2.8e-77 259.1 1.1 2.8e-77 259.1 1.1 2.0 2 0 0 2 2 2 1 Translocation protein Sec62 DUF3619 PF12279.8 KUM56263.1 - 0.44 10.9 6.3 1.2 9.5 3.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) CCDC53 PF10152.9 KUM56263.1 - 7.4 7.0 0.0 7.4 7.0 0.0 3.0 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex MFS_1 PF07690.16 KUM56265.1 - 2.5e-23 82.6 27.2 2.3e-22 79.4 25.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Mre11_DNA_bind PF04152.14 KUM56266.1 - 0.12 12.7 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain PH PF00169.29 KUM56266.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 PH domain COesterase PF00135.28 KUM56267.1 - 9.2e-62 209.5 0.0 1.9e-34 119.5 0.0 2.2 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KUM56267.1 - 6.4e-08 32.7 0.1 3.9e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold SKG6 PF08693.10 KUM56268.1 - 0.00015 21.1 0.3 0.00036 19.9 0.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 KUM56268.1 - 0.0022 18.4 13.1 0.0022 18.4 13.1 1.7 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Sporozoite_P67 PF05642.11 KUM56268.1 - 0.017 13.3 7.4 0.02 13.0 7.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RSN1_TM PF13967.6 KUM56268.1 - 0.018 14.8 0.1 0.029 14.1 0.1 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Alpha_GJ PF03229.13 KUM56268.1 - 0.025 15.2 7.6 0.061 13.9 7.6 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF5305 PF17231.2 KUM56268.1 - 0.03 13.7 0.1 0.042 13.3 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Gram_pos_anchor PF00746.21 KUM56268.1 - 0.041 13.8 0.7 0.041 13.8 0.7 2.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF2207 PF09972.9 KUM56268.1 - 0.054 12.3 0.0 0.066 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RAP1 PF07218.11 KUM56268.1 - 0.5 8.6 5.1 0.59 8.3 5.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SPESP1 PF15754.5 KUM56269.1 - 0.017 14.3 3.5 0.022 14.0 3.5 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 DUF2894 PF11445.8 KUM56269.1 - 5.1 7.5 8.1 18 5.7 8.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) NmrA PF05368.13 KUM56270.1 - 8.1e-16 58.3 0.0 9.4e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM56270.1 - 3.4e-12 46.6 0.1 3.9e-12 46.5 0.1 1.0 1 0 0 1 1 1 1 NAD(P)H-binding PALP PF00291.25 KUM56270.1 - 0.00013 21.5 0.1 0.00015 21.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme KR PF08659.10 KUM56270.1 - 0.00046 20.2 0.2 0.00056 19.9 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KUM56270.1 - 0.00079 18.9 0.1 0.0014 18.1 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Glyco_trans_4_4 PF13579.6 KUM56270.1 - 0.007 16.8 0.1 0.0083 16.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain ApbA PF02558.16 KUM56270.1 - 0.011 15.4 0.2 0.024 14.3 0.2 1.6 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.17 KUM56270.1 - 0.042 12.9 0.0 0.053 12.6 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 KUM56270.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 KUM56272.1 - 1.4e-12 47.2 22.0 1.4e-12 47.2 22.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KUM56272.1 - 0.016 14.1 3.4 0.019 13.8 3.4 1.2 1 0 0 1 1 1 0 MFS_1 like family DUF2196 PF09962.9 KUM56273.1 - 2.2e-23 82.0 0.4 4.5e-23 81.0 0.4 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Glyco_hydro_31 PF01055.26 KUM56274.1 - 1.1e-40 140.2 9.0 1.5e-40 139.7 9.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 UPRTase PF14681.6 KUM56275.1 - 8.1e-37 126.7 0.0 1.5e-36 125.8 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HAD PF12710.7 KUM56275.1 - 1.3e-12 48.5 0.0 2.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.6 KUM56275.1 - 6.7e-10 39.5 0.0 1.5e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Hydrolase PF00702.26 KUM56275.1 - 0.092 13.0 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pribosyltran PF00156.27 KUM56275.1 - 0.11 12.0 0.3 1.4 8.4 0.3 2.2 1 1 0 1 1 1 0 Phosphoribosyl transferase domain Glyco_hydro_92 PF07971.12 KUM56276.1 - 8.2e-141 470.1 4.0 1e-140 469.8 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KUM56276.1 - 8.3e-63 212.5 1.6 1.4e-62 211.7 1.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain AA_permease_2 PF13520.6 KUM56277.1 - 8.5e-75 252.2 36.2 1.1e-74 251.9 36.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM56277.1 - 2.5e-18 66.0 31.6 3.3e-18 65.6 31.6 1.1 1 0 0 1 1 1 1 Amino acid permease Osw5 PF17062.5 KUM56277.1 - 0.86 9.7 6.8 1.1 9.4 0.9 3.5 2 1 0 2 2 2 0 Outer spore wall 5 APA3_viroporin PF11289.8 KUM56277.1 - 1.3 8.5 5.3 0.42 10.1 2.0 1.8 2 0 0 2 2 2 0 Coronavirus accessory protein 3a HNH_2 PF13391.6 KUM56278.1 - 0.068 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 HNH endonuclease zf-RING_2 PF13639.6 KUM56279.1 - 6.5e-07 29.6 11.2 6.5e-06 26.4 4.7 2.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KUM56279.1 - 1.2e-06 28.7 3.9 1.2e-06 28.7 3.9 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KUM56279.1 - 0.00019 21.4 2.4 0.00019 21.4 2.4 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KUM56279.1 - 0.0082 16.0 4.9 0.0082 16.0 4.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KUM56279.1 - 0.0091 16.3 5.2 0.0091 16.3 5.2 2.0 2 0 0 2 2 1 1 RING-like domain TFIIA PF03153.13 KUM56279.1 - 0.0095 16.0 15.6 0.016 15.2 15.6 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF5082 PF16888.5 KUM56279.1 - 0.011 16.0 0.1 0.026 14.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) PHD PF00628.29 KUM56279.1 - 0.023 14.6 7.9 0.033 14.1 5.4 2.3 2 0 0 2 2 2 0 PHD-finger FANCL_C PF11793.8 KUM56279.1 - 0.053 13.7 7.5 0.23 11.7 3.7 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain Med26 PF08711.11 KUM56279.1 - 0.15 12.1 0.1 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 TFIIS helical bundle-like domain CTU2 PF10288.9 KUM56279.1 - 0.3 11.3 0.1 0.3 11.3 0.1 2.8 2 2 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-RING_4 PF14570.6 KUM56279.1 - 0.65 9.8 8.0 0.037 13.8 2.5 1.8 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KUM56279.1 - 1.4 9.2 10.7 0.14 12.3 5.1 2.1 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4 PF00097.25 KUM56279.1 - 2.1 8.3 11.2 0.043 13.7 3.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KUM56279.1 - 2.4 7.9 10.9 0.065 12.9 4.5 1.6 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KUM56279.1 - 3.4 7.5 5.8 16 5.4 1.1 2.5 2 0 0 2 2 2 0 RING-like zinc finger SDA1 PF05285.12 KUM56279.1 - 9.1 5.6 26.0 18 4.6 26.0 1.4 1 0 0 1 1 1 0 SDA1 GMC_oxred_C PF05199.13 KUM56281.1 - 5.2e-32 111.3 0.0 8.7e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KUM56281.1 - 7.2e-29 101.1 0.0 3.4e-20 72.6 0.0 3.1 3 0 0 3 3 3 3 GMC oxidoreductase NAD_binding_8 PF13450.6 KUM56281.1 - 0.0017 18.5 0.1 0.0053 17.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM56281.1 - 0.006 15.8 0.0 0.014 14.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM56281.1 - 0.018 14.1 0.2 0.035 13.2 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KUM56281.1 - 0.081 12.2 0.4 2.7 7.1 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Cyclin PF08613.11 KUM56282.1 - 3e-15 56.9 0.0 9.1e-15 55.4 0.0 1.7 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KUM56282.1 - 0.00058 19.6 0.1 0.00094 18.9 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L27A PF00828.19 KUM56283.1 - 2.5e-29 102.5 0.4 3.5e-29 102.1 0.4 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Rick_17kDa_Anti PF05433.15 KUM56284.1 - 6.2e-06 26.0 3.3 9e-06 25.5 3.3 1.2 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KUM56284.1 - 0.00016 21.6 1.3 0.00025 21.0 1.3 1.3 1 0 0 1 1 1 1 Glycine zipper TraT PF05818.12 KUM56284.1 - 0.0078 15.9 0.1 0.0078 15.9 0.1 1.4 2 0 0 2 2 2 1 Enterobacterial TraT complement resistance protein DUF533 PF04391.12 KUM56284.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Zip PF02535.22 KUM56284.1 - 0.96 8.6 13.1 1.6 7.8 13.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SPX PF03105.19 KUM56284.1 - 1.2 9.0 11.4 1.3 8.9 10.6 1.5 1 1 0 1 1 1 0 SPX domain Gly-zipper_YMGG PF13441.6 KUM56284.1 - 6.7 6.5 8.5 3.3 7.5 0.7 1.9 1 1 0 2 2 2 0 YMGG-like Gly-zipper Pkinase PF00069.25 KUM56285.1 - 3.7e-47 160.9 0.0 4.9e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM56285.1 - 6.8e-27 94.4 0.0 1.2e-20 73.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KUM56285.1 - 0.056 12.2 0.0 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase SH3_1 PF00018.28 KUM56286.1 - 1.5e-06 27.7 0.0 3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KUM56286.1 - 0.0023 17.7 0.0 0.0044 16.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_16 PF18348.1 KUM56286.1 - 0.011 15.6 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain Glyco_hydro_20 PF00728.22 KUM56288.1 - 4.8e-24 85.4 0.9 2.5e-21 76.5 0.9 2.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 KUM56288.1 - 4.9e-09 37.0 0.0 1.3e-08 35.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Cu_amine_oxid PF01179.20 KUM56289.1 - 1.5e-121 406.2 0.7 2e-121 405.8 0.7 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KUM56289.1 - 2.5e-30 104.0 0.3 5.6e-30 102.9 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 KUM56289.1 - 0.0045 17.2 0.1 0.016 15.4 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain 2OG-FeII_Oxy_3 PF13640.6 KUM56290.1 - 8.3e-09 36.2 0.3 1.1e-07 32.7 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KUM56290.1 - 0.0014 19.1 0.0 0.0027 18.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EF_assoc_1 PF08355.12 KUM56290.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.7 1 1 0 1 1 1 0 EF hand associated Aldo_ket_red PF00248.21 KUM56291.1 - 6.9e-48 163.3 0.0 5.8e-47 160.3 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family 2OG-FeII_Oxy_3 PF13640.6 KUM56292.1 - 2.2e-08 34.9 0.0 5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KUM56292.1 - 0.015 15.7 0.0 0.033 14.7 0.0 1.5 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Peptidase_M3 PF01432.20 KUM56293.1 - 4.5e-69 233.9 0.1 7.3e-69 233.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M3 S-antigen PF05756.11 KUM56293.1 - 0.11 12.9 0.5 9 6.7 0.0 2.6 2 0 0 2 2 2 0 S-antigen protein Peptidase_M3 PF01432.20 KUM56294.1 - 3.6e-30 105.7 0.0 4e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 PS_Dcarbxylase PF02666.15 KUM56295.1 - 1.9e-56 190.8 0.1 2.3e-56 190.5 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Muskelin_N PF06588.11 KUM56298.1 - 0.18 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Muskelin N-terminus tRNA-synt_1c PF00749.21 KUM56299.1 - 9.7e-103 343.3 0.0 1.3e-102 342.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KUM56299.1 - 9.8e-37 126.5 0.1 1.8e-36 125.6 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KUM56299.1 - 0.043 13.2 0.3 0.11 11.9 0.1 1.5 1 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain GST_C PF00043.25 KUM56299.1 - 0.05 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GluRS_N PF18466.1 KUM56299.1 - 0.76 10.2 0.0 0.76 10.2 0.0 2.7 3 0 0 3 3 3 0 Glutamate--tRNA ligase N-terminal domain Ribosomal_L1 PF00687.21 KUM56300.1 - 1.5e-28 99.9 0.0 1.7e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family COG2 PF06148.11 KUM56301.1 - 3.1e-37 127.6 1.6 3.1e-37 127.6 1.6 1.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 KUM56301.1 - 5.4e-06 26.4 1.0 2.3e-05 24.4 0.1 2.3 1 1 1 2 2 2 1 Vps51/Vps67 COG5 PF10392.9 KUM56301.1 - 0.00017 21.8 1.2 0.0016 18.6 0.2 2.2 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps54_N PF10475.9 KUM56301.1 - 0.046 13.0 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Bul1_C PF04426.12 KUM56301.1 - 0.054 12.9 0.1 0.16 11.3 0.0 1.8 1 1 1 2 2 2 0 Bul1 C terminus Vir_act_alpha_C PF10400.9 KUM56301.1 - 0.17 12.5 4.4 3 8.6 0.6 3.1 3 0 0 3 3 3 0 Virulence activator alpha C-term Bcr-Abl_Oligo PF09036.10 KUM56301.1 - 0.24 11.4 2.1 0.49 10.4 0.0 2.5 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain SKA2 PF16740.5 KUM56301.1 - 0.79 9.5 7.7 0.24 11.2 1.3 2.5 2 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 FlaC_arch PF05377.11 KUM56301.1 - 6.3 7.3 7.9 4.5 7.7 0.3 3.5 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) IFT57 PF10498.9 KUM56301.1 - 7.8 5.3 10.4 0.12 11.3 0.4 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Thioredoxin PF00085.20 KUM56304.1 - 2e-26 92.0 0.1 2.2e-26 91.8 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KUM56304.1 - 4.7e-06 27.0 0.3 9.3e-06 26.1 0.3 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KUM56304.1 - 6.1e-05 23.3 0.1 0.00015 22.1 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.16 KUM56304.1 - 6.4e-05 22.0 0.0 6.8e-05 21.9 0.0 1.0 1 0 0 1 1 1 1 Phosducin TraF PF13728.6 KUM56304.1 - 0.00068 19.5 0.0 0.00081 19.3 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 KUM56304.1 - 0.0011 18.9 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KUM56304.1 - 0.0024 17.7 0.0 0.0027 17.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KUM56304.1 - 0.0039 16.6 0.0 0.0048 16.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KUM56304.1 - 0.0039 17.3 0.0 0.0051 17.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 KUM56304.1 - 0.028 14.6 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_4 PF13462.6 KUM56304.1 - 0.079 13.1 0.5 2.2 8.4 0.4 2.0 1 1 1 2 2 2 0 Thioredoxin HyaE PF07449.11 KUM56304.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE RRM_1 PF00076.22 KUM56305.1 - 4.3e-24 84.1 0.1 5e-24 83.9 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KUM56305.1 - 0.00023 21.2 0.0 0.00035 20.6 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif TLP1_add_C PF18313.1 KUM56305.1 - 0.015 15.2 0.5 0.03 14.2 0.5 1.5 1 1 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain PAP_PilO PF06864.12 KUM56305.1 - 0.037 12.8 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) YflT PF11181.8 KUM56305.1 - 0.057 13.9 0.1 1.6 9.3 0.0 2.1 2 0 0 2 2 2 0 Heat induced stress protein YflT DUF4078 PF13300.6 KUM56305.1 - 0.062 13.6 0.3 0.073 13.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) RRM_3 PF08777.11 KUM56305.1 - 0.067 13.2 0.1 0.1 12.7 0.1 1.3 1 1 0 1 1 1 0 RNA binding motif Limkain-b1 PF11608.8 KUM56305.1 - 0.09 12.9 0.2 0.12 12.5 0.2 1.4 1 1 0 1 1 1 0 Limkain b1 FeoA PF04023.14 KUM56305.1 - 0.1 12.9 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 FeoA domain RRM_occluded PF16842.5 KUM56305.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif Cu-oxidase_3 PF07732.15 KUM56306.1 - 2.5e-35 121.0 1.1 2.7e-34 117.7 0.1 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KUM56306.1 - 3.7e-31 107.7 5.1 5.4e-25 87.7 1.1 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KUM56306.1 - 8.9e-16 58.4 0.0 1.4e-14 54.5 0.0 2.8 3 1 0 3 3 3 1 Multicopper oxidase Homeobox_KN PF05920.11 KUM56307.1 - 2.3e-15 56.2 2.7 5.9e-15 54.9 2.7 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KUM56307.1 - 1.2e-06 28.3 0.1 2.7e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Homeodomain HTH_Tnp_Tc5 PF03221.16 KUM56307.1 - 0.0016 18.4 0.0 0.0047 16.9 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-C2H2 PF00096.26 KUM56307.1 - 0.0029 18.0 17.7 0.21 12.1 1.1 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM56307.1 - 0.0039 17.9 1.2 0.0039 17.9 1.2 5.1 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KUM56307.1 - 0.88 10.2 6.5 1.5 9.5 0.2 2.5 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats GFA PF04828.14 KUM56308.1 - 9.6e-22 77.1 0.1 1.5e-21 76.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.16 KUM56308.1 - 0.13 12.1 0.1 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Pro-kuma_activ PF09286.11 KUM56310.1 - 4.3e-51 173.0 0.1 9.9e-50 168.5 0.1 2.4 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KUM56310.1 - 0.03 13.6 0.0 0.07 12.4 0.0 1.5 1 1 0 1 1 1 0 Subtilase family INSIG PF07281.12 KUM56313.1 - 3.3e-73 245.8 1.9 4.7e-73 245.3 1.9 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) AICARFT_IMPCHas PF01808.18 KUM56315.1 - 7.1e-89 298.2 0.0 1.2e-88 297.4 0.0 1.4 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KUM56315.1 - 6.4e-25 87.2 0.0 1.4e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain FMN_dh PF01070.18 KUM56317.1 - 1.5e-107 359.7 0.0 1.8e-107 359.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KUM56317.1 - 1.7e-06 27.3 0.2 0.00027 20.1 0.0 2.9 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KUM56317.1 - 2e-06 27.2 0.1 3.6e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KUM56317.1 - 0.0057 16.1 0.7 0.0074 15.7 0.1 1.5 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 KUM56317.1 - 0.022 14.2 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KUM56317.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family SNF2_N PF00176.23 KUM56318.1 - 1.2e-41 142.7 0.4 1.8e-41 142.0 0.4 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KUM56318.1 - 1.6e-16 60.6 0.0 3.7e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM56318.1 - 8.9e-08 32.3 0.0 2.1e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KUM56318.1 - 9.2e-06 25.0 0.0 1.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 KUM56318.1 - 0.0003 20.5 0.0 0.31 10.7 0.0 2.5 2 0 0 2 2 2 2 SWI2/SNF2 ATPase AAA_22 PF13401.6 KUM56318.1 - 0.0036 17.6 0.0 0.013 15.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KUM56318.1 - 0.023 14.7 0.1 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KUM56318.1 - 0.053 13.0 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein SAM_1 PF00536.30 KUM56318.1 - 0.088 13.3 0.1 0.26 11.8 0.1 1.8 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF2017 PF09438.10 KUM56318.1 - 0.15 12.0 1.7 15 5.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2017) GSH_synth_ATP PF03917.17 KUM56319.1 - 1.1e-131 439.1 0.0 1.3e-131 438.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KUM56319.1 - 1.7e-29 102.3 0.1 2.7e-29 101.7 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Bestrophin PF01062.21 KUM56321.1 - 4e-37 128.2 0.0 7.9e-37 127.2 0.0 1.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel T6SS_VasE PF05936.12 KUM56321.1 - 0.085 11.5 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE adh_short PF00106.25 KUM56322.1 - 4.6e-15 55.6 0.0 1.4e-12 47.5 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM56322.1 - 2.1e-07 30.7 0.1 1.2e-05 25.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM56322.1 - 4e-07 30.1 0.1 6e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.18 KUM56323.1 - 2.4e-20 72.7 0.5 1.3e-19 70.3 0.5 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM56323.1 - 8.7e-09 35.4 10.7 1.9e-08 34.3 10.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APC_rep PF18797.1 KUM56323.1 - 0.14 13.1 0.3 0.62 11.0 0.0 2.2 2 0 0 2 2 2 0 Adenomatous polyposis coli (APC) repeat Metallophos PF00149.28 KUM56324.1 - 1.7e-14 54.8 0.2 2.6e-14 54.2 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KUM56324.1 - 2.4e-10 40.9 0.1 2.4e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Transp_inhibit PF18791.1 KUM56324.1 - 0.13 11.8 0.0 0.38 10.3 0.0 1.8 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain AMP-binding PF00501.28 KUM56327.1 - 3e-66 223.8 0.0 4.1e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM56327.1 - 0.011 16.7 0.0 0.031 15.3 0.0 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain FAD_binding_7 PF03441.14 KUM56328.1 - 2.9e-81 271.8 0.2 4.9e-81 271.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KUM56328.1 - 4.6e-42 143.8 0.1 7.5e-42 143.1 0.1 1.3 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.26 KUM56328.1 - 0.14 12.6 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Universal stress protein family Peptidase_M3 PF01432.20 KUM56331.1 - 2.3e-101 340.4 0.0 3e-101 339.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 2OG-FeII_Oxy_3 PF13640.6 KUM56332.1 - 9.4e-12 45.7 0.1 2e-11 44.6 0.1 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 KUM56333.1 - 5e-08 32.6 0.0 1.3e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM56333.1 - 0.026 13.8 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase DUF2841 PF11001.8 KUM56336.1 - 0.0012 18.9 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF1843 PF08898.10 KUM56336.1 - 0.019 15.5 0.0 0.033 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) SH3_10 PF17902.1 KUM56339.1 - 7.8e-07 29.1 0.0 0.35 11.0 0.0 3.9 4 0 0 4 4 4 3 SH3 domain Tyrosinase PF00264.20 KUM56340.1 - 1.7e-54 185.4 0.2 2.4e-54 185.0 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase M20_dimer PF07687.14 KUM56342.1 - 1.1e-17 63.9 0.0 1.9e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KUM56342.1 - 6.5e-16 58.6 0.0 1.6e-14 54.1 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KUM56342.1 - 0.0054 16.4 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 AA_permease_2 PF13520.6 KUM56343.1 - 1.7e-39 135.9 47.4 2e-39 135.6 47.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM56343.1 - 2.1e-17 62.9 41.8 2.9e-17 62.4 41.8 1.1 1 0 0 1 1 1 1 Amino acid permease Meth_synt_2 PF01717.18 KUM56344.1 - 2.6e-146 487.0 0.0 6.8e-143 475.8 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KUM56344.1 - 1.3e-118 396.1 0.0 1.8e-112 375.9 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.9 KUM56344.1 - 0.16 11.7 0.5 0.47 10.3 0.1 2.1 2 0 0 2 2 2 0 Short C-terminal domain Metallophos PF00149.28 KUM56345.1 - 4.4e-10 40.4 0.7 6.3e-10 39.9 0.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase BTB PF00651.31 KUM56346.1 - 7.5e-09 35.8 0.2 2.6e-08 34.1 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain zf-C4pol PF14260.6 KUM56346.1 - 0.012 16.1 1.3 0.08 13.4 0.2 2.2 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta G-patch PF01585.23 KUM56347.1 - 8.8e-10 38.3 1.2 2e-09 37.2 1.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KUM56347.1 - 0.00095 19.2 0.5 0.00095 19.2 0.5 2.1 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.22 KUM56347.1 - 0.029 14.2 0.0 0.071 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HhH-GPD PF00730.25 KUM56348.1 - 4.5e-13 49.6 0.0 8.4e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF3589 PF12141.8 KUM56348.1 - 0.098 11.2 0.2 0.14 10.7 0.2 1.1 1 0 0 1 1 1 0 Beta-mannosyltransferases IGR PF09597.10 KUM56348.1 - 0.11 12.6 0.4 1.4 9.1 0.0 2.8 3 0 0 3 3 3 0 IGR protein motif DUF43 PF01861.16 KUM56348.1 - 0.18 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain UCR_14kD PF02271.16 KUM56349.1 - 1.9e-43 146.5 0.1 2.2e-43 146.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Ferritin PF00210.24 KUM56349.1 - 0.013 15.5 0.0 0.083 12.8 0.0 1.9 1 1 1 2 2 2 0 Ferritin-like domain Mito_carr PF00153.27 KUM56350.1 - 8.9e-65 214.7 3.0 3.4e-22 78.2 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein NAD_binding_1 PF00175.21 KUM56351.1 - 2.8e-15 56.9 0.0 6.8e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KUM56351.1 - 1.3e-09 38.6 0.1 3.6e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.24 KUM56351.1 - 1.3e-06 28.6 0.0 2.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KUM56351.1 - 1.4e-05 25.3 0.0 0.00027 21.1 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 KUM56351.1 - 0.00027 20.8 0.2 0.00052 19.9 0.2 1.4 1 0 0 1 1 1 1 Protoglobin DUF4939 PF16297.5 KUM56352.1 - 0.11 12.3 0.7 2.5 8.0 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4939) PBP1_TM PF14812.6 KUM56352.1 - 0.26 11.7 7.9 1.4 9.4 0.1 2.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF5086 PF16985.5 KUM56352.1 - 0.28 11.1 3.2 0.75 9.7 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5086) Cupin_2 PF07883.11 KUM56355.1 - 1.2e-08 34.5 0.0 1.7e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KUM56355.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 KUM56355.1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) PepX_C PF08530.10 KUM56356.1 - 8.5e-45 153.4 0.1 1.2e-44 152.9 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 KUM56356.1 - 9.6e-40 136.9 0.7 1.4e-39 136.3 0.7 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KUM56356.1 - 0.0011 18.2 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Fungal_trans PF04082.18 KUM56357.1 - 3.9e-11 42.5 2.4 7.8e-11 41.5 2.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain LigB PF02900.18 KUM56358.1 - 1.7e-10 40.5 0.0 2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase MFS_1 PF07690.16 KUM56360.1 - 4.7e-38 131.0 24.0 4.7e-38 131.0 24.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM56360.1 - 2.4e-13 49.8 18.6 8.4e-13 48.0 18.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KUM56360.1 - 3.7e-09 35.6 5.8 7.8e-09 34.5 5.8 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CPP1-like PF11833.8 KUM56360.1 - 2.1 8.0 12.3 0.18 11.5 4.2 2.9 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Aldedh PF00171.22 KUM56361.1 - 2.4e-16 59.3 0.0 3.8e-09 35.6 0.0 2.8 2 1 0 3 3 3 3 Aldehyde dehydrogenase family FAD_binding_3 PF01494.19 KUM56362.1 - 1.4e-23 83.8 0.0 2.1e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ADC PF06314.11 KUM56362.1 - 1.3e-07 31.5 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NAD_binding_8 PF13450.6 KUM56362.1 - 1.7e-07 31.4 0.1 4.3e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM56362.1 - 3.5e-07 29.7 1.2 6.7e-05 22.3 0.2 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM56362.1 - 1.6e-05 24.2 0.4 2.9e-05 23.3 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KUM56362.1 - 0.0002 21.0 0.0 0.00053 19.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KUM56362.1 - 0.0016 17.8 0.4 0.0093 15.3 0.1 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DUF1344 PF07076.11 KUM56362.1 - 0.0031 17.4 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1344) Trp_halogenase PF04820.14 KUM56362.1 - 0.0043 16.0 0.1 0.0071 15.2 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.22 KUM56362.1 - 0.0077 15.4 0.3 0.012 14.7 0.3 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KUM56362.1 - 0.015 15.9 0.4 0.051 14.1 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KUM56362.1 - 0.021 13.5 0.7 0.029 13.1 0.2 1.4 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 KUM56362.1 - 0.032 13.6 0.1 0.064 12.6 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KUM56362.1 - 0.053 12.8 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KUM56362.1 - 0.054 12.7 0.9 0.09 12.0 0.9 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mur_ligase_C PF02875.21 KUM56364.1 - 0.012 15.9 0.0 0.058 13.6 0.0 2.0 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain rve PF00665.26 KUM56366.1 - 0.017 15.3 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain Methyltransf_23 PF13489.6 KUM56368.1 - 8.9e-16 58.2 0.0 3.6e-15 56.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM56368.1 - 8.7e-08 32.8 0.0 2.7e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM56368.1 - 0.00045 20.0 0.0 0.0033 17.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM56368.1 - 0.00078 20.0 0.0 0.0019 18.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM56368.1 - 0.0037 18.0 0.0 0.053 14.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KUM56368.1 - 0.041 13.4 0.0 0.094 12.2 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase CheR PF01739.18 KUM56368.1 - 0.049 13.1 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.14 KUM56368.1 - 0.083 12.4 0.0 0.19 11.3 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain HhH-GPD PF00730.25 KUM56371.1 - 3.5e-09 37.1 0.0 6.8e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein RRM_1 PF00076.22 KUM56372.1 - 7.5e-28 96.2 0.6 5.4e-12 45.4 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VRR_NUC PF08774.11 KUM56373.1 - 5.6e-25 87.5 0.0 1.5e-24 86.1 0.0 1.8 1 0 0 1 1 1 1 VRR-NUC domain Ribosomal_S13_N PF08069.12 KUM56374.1 - 1.9e-28 98.3 0.1 3.8e-28 97.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KUM56374.1 - 1.9e-14 53.6 0.2 4.9e-14 52.3 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KUM56374.1 - 0.027 14.4 0.2 0.11 12.4 0.1 1.9 2 0 0 2 2 2 0 'Paired box' domain Dpy-30 PF05186.13 KUM56376.1 - 5.3e-15 54.8 0.0 7e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif ketoacyl-synt PF00109.26 KUM56377.1 - 4.8e-78 262.2 0.0 7.9e-78 261.5 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KUM56377.1 - 8.7e-75 251.5 9.7 5e-74 249.0 0.5 3.3 3 1 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KUM56377.1 - 5.4e-41 141.1 0.1 9.6e-41 140.3 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KUM56377.1 - 1.7e-34 118.4 0.1 5.1e-34 116.8 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 KUM56377.1 - 7.3e-27 95.0 0.0 9.2e-26 91.4 0.0 2.6 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 KUM56377.1 - 9.5e-19 67.7 0.0 1.9e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KUM56377.1 - 7.4e-16 58.3 8.4 5.9e-08 32.9 0.8 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KUM56377.1 - 8.1e-08 32.7 0.0 2.5e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 KUM56377.1 - 0.00056 20.6 0.9 0.0084 16.7 0.0 2.9 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 KUM56377.1 - 0.0054 16.1 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Cloacin PF03515.14 KUM56377.1 - 0.069 12.8 5.9 0.037 13.7 1.6 2.4 2 0 0 2 2 2 0 Colicin-like bacteriocin tRNase domain Abhydrolase_3 PF07859.13 KUM56377.1 - 0.074 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold FMO-like PF00743.19 KUM56378.1 - 3.4e-62 210.6 0.0 4.7e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KUM56378.1 - 9.7e-15 54.6 0.0 2.2e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM56378.1 - 1.7e-08 34.1 0.0 0.00014 21.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM56378.1 - 6.3e-06 25.6 0.0 2e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KUM56378.1 - 0.034 14.7 0.1 0.084 13.4 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KUM56379.1 - 2.9e-42 144.9 48.5 7.3e-41 140.3 50.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5305 PF17231.2 KUM56379.1 - 0.011 15.2 0.2 0.6 9.5 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5305) SPC25 PF06703.11 KUM56379.1 - 8.3 6.2 10.0 52 3.6 6.1 3.0 2 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) HRI1 PF16815.5 KUM56381.1 - 2.1e-17 63.6 0.1 4.1e-16 59.4 0.0 2.1 2 0 0 2 2 2 2 Protein HRI1 SLAC1 PF03595.17 KUM56382.1 - 5.2e-67 226.4 39.2 6.2e-67 226.2 39.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel MFS_1 PF07690.16 KUM56383.1 - 4.5e-31 108.1 17.2 4.5e-31 108.1 17.2 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily CT_A_B PF02626.15 KUM56385.1 - 2.1e-73 247.2 0.0 3.2e-73 246.6 0.0 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KUM56385.1 - 4.7e-52 176.6 0.0 8e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 KUM56385.1 - 9.3e-36 123.5 0.0 2.4e-35 122.1 0.0 1.7 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 KUM56385.1 - 1.8e-33 114.9 0.0 3.6e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KUM56385.1 - 1.4e-12 48.2 0.0 3.1e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KUM56385.1 - 4.3e-08 32.9 1.8 1.9e-06 27.6 1.3 3.0 2 1 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KUM56385.1 - 0.00075 19.1 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.6 KUM56385.1 - 0.018 14.5 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain LamB_YcsF PF03746.16 KUM56386.1 - 5.3e-83 278.4 0.0 6.6e-83 278.1 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family DNA_ligase_A_M PF01068.21 KUM56387.1 - 3.6e-52 177.0 0.1 2.8e-49 167.5 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KUM56387.1 - 8.6e-38 130.4 0.0 1.5e-37 129.6 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KUM56387.1 - 2.8e-18 66.3 0.1 1e-17 64.6 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KUM56387.1 - 0.00023 21.5 0.0 0.00045 20.6 0.0 1.5 1 0 0 1 1 1 1 RNA ligase Spc7_C2 PF15577.6 KUM56387.1 - 0.11 12.6 0.0 6.4 6.9 0.0 2.5 2 0 0 2 2 2 0 Spc7_C2 Whi5 PF08528.11 KUM56389.1 - 0.0069 16.0 0.4 0.014 15.0 0.4 1.5 1 0 0 1 1 1 1 Whi5 like Pyr_redox_2 PF07992.14 KUM56390.1 - 5.6e-13 48.8 0.0 1.2e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM56390.1 - 2.8e-10 39.9 0.0 3.8e-07 29.7 0.0 3.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM56390.1 - 1.6e-09 37.9 0.0 3.4e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KUM56390.1 - 1.9e-08 33.2 0.2 1.1e-07 30.7 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KUM56390.1 - 5.5e-08 32.3 0.0 0.00018 20.8 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KUM56390.1 - 5.6e-06 26.2 0.0 4.1e-05 23.3 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KUM56390.1 - 6.3e-06 26.3 0.0 0.0013 18.7 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KUM56390.1 - 0.00038 19.8 0.0 0.01 15.1 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KUM56390.1 - 0.0022 18.5 0.0 0.27 11.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KUM56390.1 - 0.0036 17.4 0.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KUM56390.1 - 0.2 10.7 0.1 0.45 9.5 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain DUF1365 PF07103.11 KUM56391.1 - 4.1e-30 105.2 0.0 5.5e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Epimerase PF01370.21 KUM56392.1 - 0.003 17.0 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KUM56392.1 - 0.031 14.2 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Chitin_synth_2 PF03142.15 KUM56393.1 - 2e-25 89.4 3.4 1.8e-23 83.0 2.2 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KUM56393.1 - 4.6e-15 56.1 4.3 1.1e-14 54.8 4.3 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KUM56393.1 - 3.5e-09 36.9 0.0 8.1e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KUM56393.1 - 0.17 11.7 0.0 23 4.7 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 La PF05383.17 KUM56394.1 - 1.6e-21 76.1 0.0 2.7e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KUM56394.1 - 1.5e-08 34.4 0.1 4.2e-08 32.9 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Plasmodium_Vir PF05795.11 KUM56394.1 - 0.07 12.5 2.3 0.48 9.8 1.8 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Dabb PF07876.12 KUM56395.1 - 5.4e-18 65.4 0.0 6e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Sulfatase PF00884.23 KUM56396.1 - 1.2e-19 70.8 1.7 2.3e-19 70.0 1.7 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KUM56396.1 - 0.00046 19.9 0.3 0.001 18.7 0.3 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KUM56396.1 - 0.11 11.0 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Cu_amine_oxidN2 PF02727.16 KUM56397.1 - 0.066 13.5 0.7 0.11 12.7 0.7 1.4 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain HSP70 PF00012.20 KUM56398.1 - 1.9e-161 538.2 2.4 1.9e-161 538.2 2.4 1.7 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KUM56398.1 - 4.1e-10 39.0 0.0 3.3e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KUM56398.1 - 0.0023 18.3 0.0 4.6 7.7 0.0 2.9 2 1 0 2 2 2 2 Cell division protein FtsA DUF2746 PF10874.8 KUM56398.1 - 0.085 13.3 0.1 0.69 10.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) p450 PF00067.22 KUM56400.1 - 4.5e-62 210.3 0.0 6e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EPSP_synthase PF00275.20 KUM56401.1 - 3.5e-128 427.9 0.0 6.6e-128 426.9 0.0 1.4 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KUM56401.1 - 3.9e-97 324.5 0.0 6.3e-97 323.8 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KUM56401.1 - 5.8e-58 196.8 0.0 1.3e-57 195.7 0.0 1.7 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KUM56401.1 - 7.8e-41 139.8 0.1 2.8e-40 138.1 0.0 1.9 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KUM56401.1 - 1.3e-23 83.0 0.0 3.5e-23 81.7 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KUM56401.1 - 2.3e-07 30.5 0.5 8.4e-07 28.6 0.1 2.2 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 KUM56401.1 - 8.9e-07 28.9 0.0 2.4e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 KUM56401.1 - 0.0028 17.7 0.0 0.007 16.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_18 PF13238.6 KUM56401.1 - 0.028 15.0 0.0 0.086 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KUM56401.1 - 0.084 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KUM56401.1 - 0.12 12.7 0.2 0.67 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KUM56401.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KUM56401.1 - 0.16 12.4 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sulfotransfer_4 PF17784.1 KUM56402.1 - 1.2e-56 192.0 0.0 1.4e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KUM56402.1 - 1.2e-06 29.1 0.1 0.00061 20.2 0.0 2.4 2 1 1 3 3 3 2 Sulfotransferase family Fungal_trans PF04082.18 KUM56404.1 - 3e-13 49.4 4.9 5.5e-13 48.6 4.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM56404.1 - 2.7e-09 37.0 10.8 5.1e-09 36.1 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HHH_8 PF14716.6 KUM56404.1 - 0.57 10.6 3.4 3.2 8.2 0.2 2.5 1 1 1 2 2 2 0 Helix-hairpin-helix domain ADH_N PF08240.12 KUM56405.1 - 9.4e-08 31.9 0.0 3.4e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM56405.1 - 1.2e-07 31.7 0.0 3e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_S31 PF05578.12 KUM56405.1 - 0.057 12.9 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 FMO-like PF00743.19 KUM56406.1 - 4.7e-42 144.1 0.0 7.1e-22 77.5 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KUM56406.1 - 5.7e-14 52.1 0.0 4.4e-07 29.5 0.0 3.3 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM56406.1 - 1.9e-09 37.1 0.0 8.6e-06 25.1 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KUM56406.1 - 3.4e-09 36.9 0.0 2.9e-08 33.9 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KUM56406.1 - 1.9e-08 33.9 0.0 1.8e-07 30.7 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM56406.1 - 1.9e-07 31.0 0.1 0.0012 18.6 0.0 3.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KUM56406.1 - 5.9e-06 26.4 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KUM56406.1 - 1.4e-05 24.4 0.1 0.00047 19.5 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KUM56406.1 - 0.0012 19.4 0.1 0.041 14.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KUM56406.1 - 0.0024 16.6 0.0 0.0098 14.6 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Shikimate_DH PF01488.20 KUM56406.1 - 0.018 15.1 0.0 0.29 11.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 KUM56406.1 - 0.076 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Malic_M PF03949.15 KUM56406.1 - 0.097 11.9 0.0 6.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain TrkA_N PF02254.18 KUM56406.1 - 0.12 12.7 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain LysM PF01476.20 KUM56407.1 - 1.6e-08 34.5 0.1 0.00052 20.0 0.2 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KUM56407.1 - 8.6e-06 26.1 3.8 8.6e-06 26.1 3.8 2.7 2 0 0 2 2 2 1 Chitin recognition protein Peptidase_S8 PF00082.22 KUM56408.1 - 1.1e-29 103.7 18.5 1.9e-29 102.9 18.5 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KUM56408.1 - 2.7e-13 50.4 0.0 4.5e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 KCNQC3-Ank-G_bd PF11956.8 KUM56409.1 - 0.058 13.7 1.1 0.11 12.8 1.0 1.4 1 1 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 F-box-like PF12937.7 KUM56410.1 - 0.0027 17.6 0.1 0.0059 16.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like TetR_C_17 PF17922.1 KUM56410.1 - 0.15 12.1 0.0 0.65 10.1 0.0 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain LRR_4 PF12799.7 KUM56410.1 - 0.21 12.1 0.8 8.1 7.0 0.0 3.7 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Rav1p_C PF12234.8 KUM56413.1 - 4e-281 934.1 0.1 5.3e-281 933.7 0.1 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 KUM56413.1 - 0.0058 17.4 3.5 0.25 12.3 0.0 4.7 6 0 0 6 6 6 1 WD domain, G-beta repeat p450 PF00067.22 KUM56414.1 - 2.6e-59 201.2 0.0 3.2e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tir_receptor_C PF07489.11 KUM56415.1 - 0.0075 16.3 1.9 0.0075 16.3 1.9 2.1 2 0 0 2 2 2 1 Translocated intimin receptor (Tir) C-terminus Sfi1 PF08457.10 KUM56416.1 - 2.7e-212 706.3 96.3 3.7e-211 702.6 87.4 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein IFRD_C PF04836.12 KUM56416.1 - 4.2 8.0 9.0 0.73 10.5 0.3 3.3 3 0 0 3 3 3 0 Interferon-related protein conserved region DUF599 PF04654.12 KUM56417.1 - 0.075 12.4 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF599 CX9C PF16860.5 KUM56418.1 - 0.0004 20.3 1.6 0.00057 19.8 1.6 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 KUM56418.1 - 0.021 14.5 1.7 1.8 8.4 0.4 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Rota_NSP4 PF01452.16 KUM56418.1 - 0.099 12.3 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Rotavirus non structural protein Cmc1 PF08583.10 KUM56418.1 - 0.12 12.4 2.8 0.28 11.2 2.8 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like FAD_binding_3 PF01494.19 KUM56419.1 - 9.1e-21 74.5 0.1 4.4e-20 72.2 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KUM56419.1 - 2.6e-08 33.4 2.8 5.6e-08 32.3 2.8 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KUM56419.1 - 3.5e-07 29.8 0.3 1e-05 24.9 0.3 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM56419.1 - 4.4e-07 30.0 1.4 1.8e-06 28.1 1.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KUM56419.1 - 4.9e-07 29.1 0.4 4.2e-06 26.1 0.4 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KUM56419.1 - 1.6e-06 27.9 2.5 4.1e-06 26.6 2.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KUM56419.1 - 3.6e-06 26.1 1.2 0.0076 15.2 0.3 3.1 2 1 1 3 3 3 2 Tryptophan halogenase FAD_oxidored PF12831.7 KUM56419.1 - 1e-05 25.1 0.8 1.8e-05 24.3 0.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KUM56419.1 - 1.8e-05 23.7 0.4 2.8e-05 23.0 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KUM56419.1 - 4.5e-05 22.8 0.1 8.4e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KUM56419.1 - 0.00013 21.2 0.2 0.00017 20.8 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KUM56419.1 - 0.00053 19.3 1.1 0.00092 18.6 1.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KUM56419.1 - 0.0026 17.1 0.3 0.0045 16.3 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KUM56419.1 - 0.005 17.4 0.2 0.026 15.1 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KUM56419.1 - 0.023 14.0 0.4 0.11 11.7 0.2 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase ApbA PF02558.16 KUM56419.1 - 0.17 11.5 0.3 0.28 10.8 0.3 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 KUM56419.1 - 0.29 11.1 0.9 3.6 7.6 0.6 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding AD PF09793.9 KUM56420.1 - 1e-26 92.9 0.0 1.6e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain GTP_EFTU PF00009.27 KUM56421.1 - 4.6e-08 32.8 0.0 7.7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KUM56421.1 - 0.061 13.2 0.2 8.7 6.2 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase HSP70 PF00012.20 KUM56422.1 - 5.8e-06 24.8 0.0 1.6e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Hsp70 protein Sua5_yciO_yrdC PF01300.18 KUM56423.1 - 2.1e-15 56.7 0.0 5.4e-15 55.4 0.0 1.6 1 1 0 1 1 1 1 Telomere recombination P53_tetramer PF07710.11 KUM56424.1 - 0.11 11.9 0.1 0.23 10.8 0.1 1.6 1 0 0 1 1 1 0 P53 tetramerisation motif OmpH PF03938.14 KUM56424.1 - 0.24 11.7 6.2 6 7.2 0.0 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AA_permease_2 PF13520.6 KUM56425.1 - 2.9e-53 181.2 36.6 3.5e-53 181.0 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM56425.1 - 4.4e-19 68.4 29.4 5.6e-19 68.1 29.4 1.1 1 0 0 1 1 1 1 Amino acid permease Aconitase PF00330.20 KUM56426.1 - 5.6e-159 530.0 0.0 6.8e-159 529.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KUM56426.1 - 1e-39 135.8 0.0 1.9e-39 135.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Glycos_transf_4 PF00953.21 KUM56427.1 - 6.6e-32 110.7 11.3 6.6e-32 110.7 11.3 2.3 3 1 0 3 3 3 1 Glycosyl transferase family 4 SecE PF00584.20 KUM56427.1 - 0.97 9.4 13.4 2.4 8.2 0.0 4.6 5 0 0 5 5 5 0 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.32 KUM56428.1 - 1.7e-11 44.5 16.2 0.00087 20.1 0.7 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM56428.1 - 2.9e-05 24.3 0.1 0.41 11.0 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KUM56428.1 - 0.0056 15.7 0.1 6.6 5.6 0.0 3.1 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KUM56428.1 - 0.01 14.5 1.4 0.57 8.8 0.2 2.4 2 0 0 2 2 2 0 Nucleoporin Nup120/160 ADH_zinc_N PF00107.26 KUM56429.1 - 4.6e-11 42.8 0.0 9.7e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM56429.1 - 0.0011 20.1 0.0 0.0022 19.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM56429.1 - 0.0024 17.7 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain UNC-93 PF05978.16 KUM56430.1 - 4.7e-07 29.6 3.5 4.7e-07 29.6 3.5 2.6 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KUM56430.1 - 6.7e-07 28.5 39.4 5.3e-06 25.6 39.5 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily AA_permease PF00324.21 KUM56431.1 - 2.2e-48 165.0 31.1 5e-48 163.9 31.1 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM56431.1 - 2.3e-15 56.4 29.0 4.1e-15 55.6 29.0 1.5 1 1 0 1 1 1 1 Amino acid permease p450 PF00067.22 KUM56433.1 - 1.8e-72 244.6 0.0 2.2e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PhyH PF05721.13 KUM56434.1 - 5.5e-22 79.1 0.0 7e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AMP-binding PF00501.28 KUM56435.1 - 4.4e-136 453.8 0.0 9.9e-68 228.7 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KUM56435.1 - 3.2e-93 312.9 0.0 2.6e-74 250.6 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KUM56435.1 - 3.2e-25 88.3 1.0 8.9e-14 51.6 0.0 3.7 3 0 0 3 3 3 2 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 KUM56435.1 - 4.1e-06 27.4 0.0 2.4e-05 25.0 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding_C PF13193.6 KUM56435.1 - 6.2e-05 23.9 0.0 0.28 12.2 0.0 3.5 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Methyltransf_31 PF13847.6 KUM56435.1 - 0.00012 21.9 0.0 0.0004 20.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM56435.1 - 0.0004 21.1 0.0 0.0013 19.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM56435.1 - 0.002 18.0 0.0 0.0053 16.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM56435.1 - 0.0024 18.5 0.0 0.0098 16.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KUM56436.1 - 6.3e-47 160.1 0.4 7.7e-47 159.8 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM56436.1 - 1.4e-40 138.9 0.1 1.9e-40 138.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM56436.1 - 1.7e-12 47.6 0.2 1.4e-11 44.6 0.3 1.9 2 0 0 2 2 2 1 KR domain Ribosomal_L17 PF01196.19 KUM56436.1 - 0.023 15.6 0.1 0.39 11.6 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L17 DUF1712 PF08217.11 KUM56437.1 - 6.4e-14 51.4 0.0 7.5e-12 44.5 0.0 2.3 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Ima1_N PF09779.9 KUM56438.1 - 2.6e-32 112.5 2.2 2.6e-32 112.5 2.2 2.3 3 0 0 3 3 3 1 Ima1 N-terminal domain Zn_Tnp_IS1595 PF12760.7 KUM56438.1 - 0.16 12.0 6.6 0.029 14.3 2.6 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 KUM56438.1 - 0.24 11.3 1.0 1.3 9.0 1.4 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Alg14 PF08660.11 KUM56439.1 - 9.3e-55 185.3 0.0 2e-54 184.1 0.0 1.5 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Formyl_trans_N PF00551.19 KUM56440.1 - 1.2e-21 77.3 0.0 2.1e-21 76.5 0.0 1.4 1 1 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KUM56440.1 - 0.00045 20.4 0.0 0.00084 19.5 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Chorismate_synt PF01264.21 KUM56441.1 - 7.6e-67 225.3 0.0 9.1e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase BPL_LplA_LipB PF03099.19 KUM56442.1 - 5.4e-08 32.8 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF2264 PF10022.9 KUM56443.1 - 3.4e-142 473.7 0.0 4.2e-142 473.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Sugar_tr PF00083.24 KUM56444.1 - 5.1e-119 398.1 25.9 5.8e-119 397.9 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM56444.1 - 1.8e-15 56.7 44.1 2.7e-15 56.1 37.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_3 PF07969.11 KUM56445.1 - 4.1e-70 237.6 0.1 4.7e-70 237.4 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KUM56445.1 - 1.1e-12 48.0 0.2 2.5e-07 30.3 0.1 3.2 2 1 0 2 2 2 2 Amidohydrolase family DUF1445 PF07286.12 KUM56446.1 - 1.6e-36 125.4 0.0 1.8e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Myb_DNA-binding PF00249.31 KUM56447.1 - 7.3e-10 38.9 0.0 6.3e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KUM56447.1 - 0.011 15.6 0.1 0.03 14.2 0.1 1.7 1 0 0 1 1 1 0 Myb DNA-binding like MFS_1 PF07690.16 KUM56448.1 - 8.5e-41 140.0 23.6 1.1e-40 139.7 23.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KUM56449.1 - 1.6e-08 33.9 0.0 5.3e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cation_efflux PF01545.21 KUM56450.1 - 9.7e-22 77.7 9.4 1.2e-21 77.4 9.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KUM56450.1 - 1.5e-06 28.2 0.4 2.8e-06 27.4 0.4 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF2721 PF11026.8 KUM56450.1 - 1.5 8.7 0.0 1.5 8.7 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) p450 PF00067.22 KUM56451.1 - 1.5e-62 211.9 0.0 1.8e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAM104 PF15434.6 KUM56452.1 - 0.87 10.2 4.9 1.7 9.2 4.9 1.5 1 0 0 1 1 1 0 Family 104 Dicty_REP PF05086.12 KUM56452.1 - 1.9 6.4 4.3 2.5 5.9 4.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sugar_tr PF00083.24 KUM56453.1 - 3.3e-82 276.8 21.9 4e-82 276.5 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM56453.1 - 6.7e-16 58.1 49.1 2.5e-14 53.0 27.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CBF PF03914.17 KUM56455.1 - 2.2e-56 190.5 0.2 1.4e-55 187.9 0.1 2.5 2 0 0 2 2 2 1 CBF/Mak21 family Hamartin PF04388.12 KUM56455.1 - 8.9 4.8 14.1 18 3.8 14.1 1.4 1 0 0 1 1 1 0 Hamartin protein Acetyltransf_10 PF13673.7 KUM56456.1 - 2.6e-12 46.8 0.0 4.4e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM56456.1 - 4.6e-12 46.2 0.0 8.3e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KUM56456.1 - 3.9e-10 40.0 0.1 8.9e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KUM56456.1 - 0.022 14.9 0.0 0.061 13.5 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KUM56456.1 - 0.028 14.5 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_22 PF03901.17 KUM56457.1 - 9.3e-81 272.2 16.1 1.1e-80 271.9 16.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family EF-hand_11 PF08976.11 KUM56457.1 - 0.079 13.8 0.0 0.16 12.8 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain ArfGap PF01412.18 KUM56458.1 - 6.4e-34 116.5 0.1 1.4e-33 115.4 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Presenilin PF01080.17 KUM56458.1 - 8.1 5.1 9.9 17 4.1 9.9 1.5 1 0 0 1 1 1 0 Presenilin Aminotran_3 PF00202.21 KUM56459.1 - 3.8e-118 394.7 0.0 4.4e-118 394.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KUM56459.1 - 0.003 16.8 0.0 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KUM56459.1 - 0.097 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase PITH PF06201.13 KUM56460.1 - 1.5e-35 122.7 0.0 2.7e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KUM56460.1 - 1.8e-27 95.3 0.1 3.3e-27 94.5 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KUM56460.1 - 2e-07 31.4 0.3 2.7e-06 27.8 0.3 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KUM56460.1 - 4.8e-06 26.8 0.0 0.0031 17.8 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 KUM56460.1 - 2.3e-05 23.9 0.1 6.5e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KUM56460.1 - 0.0002 21.1 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KUM56460.1 - 0.0016 18.3 0.0 0.27 11.1 0.0 2.3 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KUM56460.1 - 0.0022 17.7 0.2 0.075 12.8 0.0 2.3 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 KUM56460.1 - 0.028 14.6 0.0 0.082 13.1 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 KUM56460.1 - 0.042 13.8 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 KUM56460.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin peroxidase PF00141.23 KUM56461.1 - 4.1e-48 164.1 0.0 6.5e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase zf-CSL PF05207.13 KUM56462.1 - 1.7e-18 66.1 2.3 2.5e-18 65.5 2.3 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KUM56462.1 - 2.5e-11 43.5 0.1 4e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 DnaJ domain AA_permease_2 PF13520.6 KUM56463.1 - 2.4e-45 155.2 54.8 2.9e-45 154.9 54.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM56463.1 - 3e-17 62.4 46.7 4e-17 62.0 46.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1035 PF06281.12 KUM56463.1 - 3 7.9 9.8 0.53 10.3 4.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1035) DUF1993 PF09351.10 KUM56464.1 - 1.4e-47 161.9 0.1 1.5e-47 161.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) PipA PF07108.11 KUM56464.1 - 0.033 13.7 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 PipA protein HSP33 PF01430.19 KUM56464.1 - 0.05 13.0 0.2 3.1 7.1 0.0 2.0 1 1 1 2 2 2 0 Hsp33 protein DUF4620 PF15399.6 KUM56465.1 - 0.1 13.0 0.1 0.25 11.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) DUF1857 PF08982.11 KUM56466.1 - 0.089 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) Zn_clus PF00172.18 KUM56467.1 - 1.9e-08 34.2 11.1 3.5e-08 33.4 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM56467.1 - 9.3e-07 28.0 1.0 1.4e-06 27.4 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.21 KUM56469.1 - 1.2e-08 34.7 0.0 1.4e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Jacalin PF01419.17 KUM56470.1 - 7.8e-05 22.6 0.1 0.00012 22.1 0.1 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain ThrE PF06738.12 KUM56471.1 - 1.2e-70 237.6 15.9 9.1e-63 211.8 5.5 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KUM56471.1 - 6e-12 45.8 28.0 1e-11 45.1 9.4 2.5 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Tom5 PF10642.9 KUM56471.1 - 0.56 10.3 2.2 1.5 8.9 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase Abhydrolase_6 PF12697.7 KUM56472.1 - 1.2e-15 58.7 3.7 1.5e-15 58.4 3.7 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM56472.1 - 6.8e-15 55.4 0.6 1.2e-14 54.6 0.5 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM56472.1 - 3.2e-11 43.0 0.3 5.6e-11 42.2 0.3 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KUM56472.1 - 0.0004 20.1 0.0 0.00056 19.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 KUM56472.1 - 0.0031 17.7 0.0 0.0049 17.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.16 KUM56472.1 - 0.017 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 KUM56472.1 - 0.037 13.6 0.4 0.12 11.9 0.4 1.8 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase TFIIIC_sub6 PF10419.9 KUM56473.1 - 6.3e-23 80.5 0.0 1.1e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain ELFV_dehydrog PF00208.21 KUM56474.1 - 1e-65 221.9 0.0 1.5e-65 221.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KUM56474.1 - 6.6e-17 60.4 0.0 5.5e-12 44.1 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KUM56474.1 - 0.018 15.0 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain AA_permease PF00324.21 KUM56478.1 - 4.8e-98 328.8 35.0 6.3e-98 328.4 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM56478.1 - 1.4e-13 50.5 38.2 1.8e-13 50.1 38.2 1.1 1 0 0 1 1 1 1 Amino acid permease Cupin_8 PF13621.6 KUM56479.1 - 6e-22 78.6 0.0 2.5e-21 76.5 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KUM56479.1 - 0.08 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Pyr_redox_3 PF13738.6 KUM56480.1 - 5.2e-10 39.1 0.1 0.00034 19.9 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KUM56480.1 - 5.1e-07 28.5 1.0 9e-06 24.4 1.0 2.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KUM56480.1 - 3.3e-06 26.5 0.4 7.7e-05 22.0 0.1 2.8 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KUM56480.1 - 0.0037 17.4 0.0 0.01 16.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain LIN52 PF10044.9 KUM56480.1 - 0.022 15.5 0.0 0.072 13.8 0.0 1.8 1 0 0 1 1 1 0 Retinal tissue protein Thi4 PF01946.17 KUM56480.1 - 0.073 12.3 0.1 2.2 7.5 0.0 2.7 3 0 0 3 3 3 0 Thi4 family Zn_clus PF00172.18 KUM56481.1 - 4.2e-05 23.6 9.2 7e-05 22.9 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM56482.1 - 1.1e-18 67.2 0.1 1.9e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CK_II_beta PF01214.18 KUM56483.1 - 5.9e-78 260.9 0.0 1.4e-77 259.6 0.0 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.8 KUM56483.1 - 0.76 10.8 14.4 0.11 13.5 7.4 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal FAM176 PF14851.6 KUM56483.1 - 8 6.1 7.1 4.8 6.8 3.0 2.0 2 0 0 2 2 2 0 FAM176 family RRN3 PF05327.11 KUM56483.1 - 8.9 4.7 7.2 0.2 10.2 1.0 1.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 BetaGal_dom4_5 PF13364.6 KUM56484.1 - 0.0013 19.3 0.1 0.0045 17.6 0.1 1.9 2 1 0 2 2 2 1 Beta-galactosidase jelly roll domain PseudoU_synth_2 PF00849.22 KUM56485.1 - 3.1e-27 95.6 0.0 6e-27 94.7 0.0 1.5 2 0 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.25 KUM56485.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 S4 domain Fringe PF02434.16 KUM56486.1 - 2.3e-05 24.0 3.7 0.00033 20.2 0.1 3.4 3 1 0 3 3 3 1 Fringe-like PAN_4 PF14295.6 KUM56486.1 - 0.13 12.2 0.7 0.36 10.8 0.7 1.7 1 0 0 1 1 1 0 PAN domain Ribosomal_L32e PF01655.18 KUM56487.1 - 3.8e-50 168.8 0.9 6e-50 168.2 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L32 GFO_IDH_MocA PF01408.22 KUM56488.1 - 3e-18 66.8 0.0 5.5e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KUM56488.1 - 0.00013 21.9 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sec2p PF06428.11 KUM56489.1 - 1.2e-09 38.0 11.2 1.2e-09 38.0 11.2 1.9 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Jnk-SapK_ap_N PF09744.9 KUM56489.1 - 0.0018 18.5 17.4 0.51 10.5 13.9 2.1 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 bZIP_1 PF00170.21 KUM56489.1 - 0.0048 17.0 12.3 0.15 12.2 0.0 3.3 2 1 1 3 3 3 2 bZIP transcription factor ATG16 PF08614.11 KUM56489.1 - 0.011 16.0 23.9 0.063 13.5 17.7 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FAM76 PF16046.5 KUM56489.1 - 0.037 13.4 4.1 0.057 12.8 4.1 1.3 1 1 0 1 1 1 0 FAM76 protein Cluap1 PF10234.9 KUM56489.1 - 0.064 12.7 10.5 0.029 13.8 7.7 1.7 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF2746 PF10874.8 KUM56489.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Exonuc_VII_L PF02601.15 KUM56489.1 - 0.14 11.7 12.4 0.16 11.5 8.8 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 KUM56489.1 - 0.24 11.6 3.6 24 5.1 0.0 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KUM56489.1 - 0.25 10.6 7.6 2 7.7 6.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) YlqD PF11068.8 KUM56489.1 - 0.47 10.8 11.8 0.45 10.9 9.5 1.9 2 0 0 2 2 2 0 YlqD protein YabA PF06156.13 KUM56489.1 - 0.58 10.8 4.2 41 4.9 0.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Vac_Fusion PF02346.16 KUM56489.1 - 1.2 8.9 4.8 5.6 6.7 2.1 2.4 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 SlyX PF04102.12 KUM56489.1 - 1.5 9.5 14.0 28 5.4 0.0 4.0 2 1 2 4 4 4 0 SlyX TMPIT PF07851.13 KUM56489.1 - 1.9 7.7 4.5 25 4.0 0.0 2.1 2 0 0 2 2 2 0 TMPIT-like protein HR1 PF02185.16 KUM56489.1 - 6.2 7.0 19.1 18 5.5 12.3 3.4 2 2 0 2 2 2 0 Hr1 repeat XhlA PF10779.9 KUM56489.1 - 7.9 6.8 6.5 29 4.9 0.0 2.8 3 0 0 3 3 3 0 Haemolysin XhlA Glyco_hydro_35 PF01301.19 KUM56492.1 - 5.9e-41 141.1 0.1 6.6e-41 141.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 NA37 PF04245.13 KUM56492.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein MFS_1 PF07690.16 KUM56494.1 - 2e-42 145.4 59.5 1.1e-30 106.7 25.1 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM56494.1 - 5.5e-06 25.1 24.6 1e-05 24.2 24.0 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3989 PF13150.6 KUM56494.1 - 0.0078 15.9 0.6 0.64 9.8 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3989) MFS_1 PF07690.16 KUM56495.1 - 3.2e-29 102.0 49.4 1.1e-28 100.1 49.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_32 PF13679.6 KUM56495.1 - 1.4e-21 77.1 1.1 6.6e-21 74.9 1.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Sugar_tr PF00083.24 KUM56495.1 - 2.8e-08 33.1 5.8 2.8e-08 33.1 5.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DIT1_PvcA PF05141.12 KUM56496.1 - 1.1e-91 307.2 0.0 1.7e-91 306.6 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.28 KUM56496.1 - 1.8e-27 96.0 0.0 2.9e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.15 KUM56496.1 - 9.9e-11 40.9 0.0 4.1e-07 29.0 0.0 3.0 2 1 0 2 2 2 2 Transferase family PP-binding PF00550.25 KUM56496.1 - 3.5e-06 27.3 0.0 7.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site MFS_1 PF07690.16 KUM56497.1 - 4.1e-22 78.6 62.9 3.8e-14 52.4 39.3 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF3723 PF12520.8 KUM56498.1 - 1.7e-184 614.3 0.0 2.2e-184 613.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Sel_put PF04328.13 KUM56498.1 - 0.027 14.5 0.0 0.077 13.0 0.0 1.7 1 0 0 1 1 1 0 Selenoprotein, putative PV-1 PF06637.11 KUM56499.1 - 0.031 13.1 5.3 0.05 12.4 5.3 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) OmpH PF03938.14 KUM56499.1 - 0.12 12.7 3.2 0.25 11.7 3.2 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Vps39_2 PF10367.9 KUM56499.1 - 0.14 12.6 0.7 2.5 8.6 0.2 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 PDDEXK_6 PF04720.12 KUM56499.1 - 2 8.3 5.3 0.78 9.7 0.6 2.3 2 1 0 2 2 2 0 PDDEXK-like family of unknown function DUF3435 PF11917.8 KUM56500.1 - 3.8e-148 493.9 0.0 5.4e-148 493.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_int_SAM_5 PF13102.6 KUM56500.1 - 0.04 14.2 0.1 0.097 13.0 0.1 1.6 1 0 0 1 1 1 0 Phage integrase SAM-like domain T3SS_basalb_I PF17001.5 KUM56500.1 - 0.056 14.0 1.8 0.2 12.3 0.6 2.5 2 0 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI zf-C2H2_4 PF13894.6 KUM56500.1 - 0.43 11.5 5.9 1.3 10.0 0.5 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger DNA_primase_lrg PF04104.14 KUM56500.1 - 0.47 9.8 5.0 0.28 10.5 0.1 2.4 2 0 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit zf-C2H2 PF00096.26 KUM56500.1 - 1.7 9.3 5.7 1.2 9.8 0.5 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Filament PF00038.21 KUM56501.1 - 0.0033 17.0 21.5 0.0033 17.0 21.5 2.2 2 1 0 2 2 2 1 Intermediate filament protein eIF2_C PF09173.11 KUM56501.1 - 0.12 12.6 0.9 0.29 11.4 0.9 1.6 1 0 0 1 1 1 0 Initiation factor eIF2 gamma, C terminal PYC_OADA PF02436.18 KUM56501.1 - 1.8 8.2 7.5 0.43 10.3 3.1 2.2 3 0 0 3 3 3 0 Conserved carboxylase domain V_ATPase_I PF01496.19 KUM56501.1 - 6.3 4.6 21.8 0.036 12.0 9.6 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family ETF_QO PF05187.13 KUM56502.1 - 2.1e-47 159.6 0.4 3.3e-47 158.9 0.4 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 KUM56502.1 - 3.9e-07 29.5 0.2 0.0015 17.7 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KUM56502.1 - 4.2e-07 29.9 0.5 0.00033 20.4 0.2 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KUM56502.1 - 1.6e-06 28.2 0.0 5.3e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM56502.1 - 2.1e-05 23.9 0.0 9.4e-05 21.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KUM56502.1 - 0.00028 20.4 0.0 0.00042 19.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KUM56502.1 - 0.00047 19.0 0.3 0.00074 18.3 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KUM56502.1 - 0.0005 20.6 0.1 0.72 10.4 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KUM56502.1 - 0.00072 18.9 0.2 0.0013 18.1 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KUM56502.1 - 0.00089 19.3 0.0 0.0036 17.3 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KUM56502.1 - 0.00094 18.5 0.0 0.022 14.0 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KUM56502.1 - 0.0069 15.7 0.5 0.011 15.0 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KUM56502.1 - 0.009 14.9 0.1 0.19 10.5 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Fer4_7 PF12838.7 KUM56502.1 - 0.012 16.2 0.9 0.036 14.7 0.9 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 KUM56502.1 - 0.068 12.2 0.2 0.1 11.6 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_2 PF12797.7 KUM56502.1 - 0.12 12.6 0.6 0.3 11.3 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain GIDA PF01134.22 KUM56502.1 - 0.16 11.0 0.4 0.27 10.3 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TBP PF00352.21 KUM56503.1 - 1.9e-67 223.2 0.1 1.2e-32 111.7 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KUM56503.1 - 9.3e-05 22.5 0.0 0.28 11.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KUM56503.1 - 0.18 11.7 0.1 0.85 9.5 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) MFS_1 PF07690.16 KUM56504.1 - 2.9e-28 98.8 34.8 2.9e-28 98.8 34.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KUM56504.1 - 2.3e-07 30.4 6.8 2.3e-07 30.4 6.8 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB A_deaminase PF00962.22 KUM56505.1 - 5.7e-39 134.4 0.0 6.8e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KUM56505.1 - 0.017 14.4 0.0 0.033 13.5 0.0 1.5 1 1 0 1 1 1 0 Amidohydrolase family DAO PF01266.24 KUM56506.1 - 4.2e-47 161.4 1.0 4.8e-47 161.2 1.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM56506.1 - 1e-08 34.8 0.0 0.0016 17.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM56506.1 - 1.5e-06 28.2 0.1 0.058 13.4 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KUM56506.1 - 7.9e-05 21.9 0.1 0.013 14.6 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.22 KUM56506.1 - 7.9e-05 21.9 0.0 0.00062 19.0 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KUM56506.1 - 7.9e-05 21.7 0.0 0.011 14.6 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 KUM56506.1 - 0.00028 21.1 1.3 0.0005 20.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KUM56506.1 - 0.00093 19.7 0.0 0.0028 18.2 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KUM56506.1 - 0.0093 15.4 0.0 0.41 10.0 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KUM56506.1 - 0.014 14.5 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 KUM56506.1 - 0.022 15.0 0.0 0.086 13.1 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.17 KUM56506.1 - 0.032 13.5 0.0 0.078 12.2 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Methyltransf_23 PF13489.6 KUM56507.1 - 2.4e-35 121.8 0.0 3.2e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM56507.1 - 1.8e-06 28.6 0.0 3.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM56507.1 - 2.4e-06 28.2 0.0 1.7e-05 25.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM56507.1 - 0.00055 20.5 0.0 0.0043 17.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM56507.1 - 0.0051 16.6 0.0 0.0088 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM56507.1 - 0.075 12.4 0.0 0.47 9.7 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF3212 PF11486.8 KUM56508.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) RRM_1 PF00076.22 KUM56509.1 - 1.6e-14 53.4 0.0 2.1e-08 33.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GATase PF00117.28 KUM56510.1 - 0.00019 21.3 0.0 0.00028 20.7 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I ThiJ_like PF17124.5 KUM56510.1 - 0.0047 16.6 0.0 0.0064 16.2 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like SNO PF01174.19 KUM56510.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Beta_elim_lyase PF01212.21 KUM56511.1 - 1.8e-66 224.4 0.0 2.1e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KUM56511.1 - 0.003 16.8 0.0 0.0037 16.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KUM56511.1 - 0.0041 16.5 0.0 0.0067 15.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KUM56511.1 - 0.13 10.7 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DDHD PF02862.17 KUM56512.1 - 1.2 9.2 10.9 1.9 8.6 6.0 2.4 2 0 0 2 2 2 0 DDHD domain Peptidase_M20 PF01546.28 KUM56513.1 - 2.6e-20 73.0 0.0 4.2e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KUM56513.1 - 2.8e-14 52.9 0.0 2.5e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain HAD_2 PF13419.6 KUM56514.1 - 0.059 13.4 0.0 0.18 11.9 0.0 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase zinc-ribbons_6 PF07191.12 KUM56514.1 - 0.091 12.8 0.0 5.8 7.0 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbons Hydrolase PF00702.26 KUM56514.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase adh_short PF00106.25 KUM56515.1 - 6e-44 149.9 0.1 7.6e-44 149.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM56515.1 - 5.1e-28 98.2 0.0 5.7e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM56515.1 - 5.7e-07 29.6 0.0 8.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KUM56515.1 - 0.00065 19.6 0.0 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KUM56515.1 - 0.035 13.2 0.1 0.068 12.3 0.0 1.4 2 0 0 2 2 2 0 RmlD substrate binding domain Epimerase PF01370.21 KUM56515.1 - 0.036 13.5 0.1 0.09 12.2 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DAO PF01266.24 KUM56516.1 - 1.2e-43 150.1 0.2 1.8e-43 149.5 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KUM56516.1 - 6e-06 25.7 0.0 1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KUM56516.1 - 1.2e-05 25.5 0.2 5.3e-05 23.4 0.2 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Fungal_trans PF04082.18 KUM56516.1 - 0.0001 21.5 0.0 0.00021 20.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.6 KUM56516.1 - 0.00025 20.4 0.1 0.33 10.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM56516.1 - 0.00095 19.2 0.4 0.011 15.8 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KUM56516.1 - 0.0014 18.0 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KUM56516.1 - 0.017 14.2 0.1 0.035 13.2 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KUM56516.1 - 0.032 13.3 0.1 0.05 12.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KUM56516.1 - 0.2 10.3 0.0 3.7 6.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein AA_permease PF00324.21 KUM56517.1 - 5.3e-109 365.0 42.2 6.5e-109 364.7 42.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM56517.1 - 8.3e-27 94.1 43.0 1.1e-26 93.6 43.0 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_MOT1 PF16983.5 KUM56517.1 - 0.0067 16.8 5.1 0.0067 16.8 5.1 2.8 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily NIBRIN_BRCT_II PF16508.5 KUM56518.1 - 1.3e-35 122.3 0.0 3.5e-35 120.9 0.0 1.7 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KUM56518.1 - 8.5e-08 32.4 0.2 1.6e-07 31.6 0.2 1.5 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 KUM56518.1 - 0.016 15.1 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain DUF4138 PF13595.6 KUM56518.1 - 0.032 13.5 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) Mannosyl_trans PF05007.13 KUM56519.1 - 1.7e-76 257.5 12.5 2.2e-76 257.2 12.5 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KUM56519.1 - 4.8e-10 39.0 16.5 5.1e-09 35.6 16.5 2.0 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KUM56519.1 - 3.3e-06 27.0 28.6 3.3e-06 27.0 28.6 2.5 1 1 1 2 2 2 1 Glycosyltransferase family 87 IRF-2BP1_2 PF11261.8 KUM56520.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger F-box-like PF12937.7 KUM56521.1 - 0.00021 21.1 0.0 0.00075 19.3 0.0 2.1 1 0 0 1 1 1 1 F-box-like PD-C2-AF1 PF09310.10 KUM56521.1 - 0.028 13.8 0.7 0.048 13.1 0.7 1.3 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 Glyco_hydro_12 PF01670.16 KUM56522.1 - 3.9e-06 27.0 1.0 4.3e-06 26.9 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Fungal_trans PF04082.18 KUM56523.1 - 1.1e-15 57.4 0.1 2.3e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM56523.1 - 3.4e-06 27.1 14.6 6.4e-06 26.2 14.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3913 PF13052.6 KUM56523.1 - 0.18 12.1 0.1 1.1 9.6 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3913) IMS PF00817.20 KUM56524.1 - 3e-43 147.4 0.3 5.7e-43 146.5 0.3 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KUM56524.1 - 6.1e-14 52.7 0.2 1.9e-13 51.2 0.1 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KUM56524.1 - 2.1e-06 27.7 0.0 6.1e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif BAF PF02961.14 KUM56524.1 - 0.0045 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Barrier to autointegration factor DUF3712 PF12505.8 KUM56525.1 - 2.8e-30 105.2 1.8 3.1e-30 105.0 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Rhodanese PF00581.20 KUM56526.1 - 1.2e-16 61.1 0.0 8e-10 39.2 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Mannosidase_ig PF17786.1 KUM56527.1 - 8.9e-19 67.9 0.1 2.2e-18 66.6 0.1 1.7 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KUM56527.1 - 4.8e-15 56.2 0.1 1.3e-14 54.8 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KUM56527.1 - 3.1e-05 23.9 0.3 0.00021 21.2 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF1151 PF06625.11 KUM56528.1 - 6.9 6.7 7.4 41 4.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1151) Kinesin PF00225.23 KUM56529.1 - 4.2e-111 371.1 0.8 4.2e-111 371.1 0.8 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KUM56529.1 - 7e-25 87.7 0.1 4.6e-24 85.1 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 KUM56529.1 - 3.3e-08 34.0 2.5 3.3e-08 34.0 2.5 4.8 4 2 1 5 5 5 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.12 KUM56529.1 - 0.00053 20.0 22.6 0.051 13.6 0.0 6.2 2 1 4 7 7 7 3 Baculovirus polyhedron envelope protein, PEP, C terminus DAP_B PF07930.12 KUM56529.1 - 0.06 13.3 4.3 0.86 9.6 0.5 2.8 2 0 0 2 2 2 0 D-aminopeptidase, domain B TMPIT PF07851.13 KUM56529.1 - 0.21 10.8 28.4 0.46 9.7 0.7 4.5 4 0 0 4 4 4 0 TMPIT-like protein RNase_H2-Ydr279 PF09468.10 KUM56529.1 - 0.28 11.4 4.9 0.42 10.8 2.6 2.6 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain TBCA PF02970.16 KUM56529.1 - 1.4 9.3 26.1 0.023 15.0 4.1 5.1 3 2 0 5 5 5 0 Tubulin binding cofactor A Peroxin-13_N PF04088.13 KUM56529.1 - 6.2 7.1 8.3 1.9 8.7 0.3 3.2 2 1 0 2 2 2 0 Peroxin 13, N-terminal region DUF948 PF06103.11 KUM56529.1 - 6.3 7.1 30.8 2.8 8.3 0.9 7.1 3 3 3 6 6 6 0 Bacterial protein of unknown function (DUF948) UPF0183 PF03676.14 KUM56530.1 - 1.7e-52 179.0 0.0 9.1e-34 117.4 0.0 2.9 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) Translin PF01997.16 KUM56531.1 - 8.6e-70 234.9 0.1 1e-69 234.7 0.1 1.0 1 0 0 1 1 1 1 Translin family RPEL PF02755.15 KUM56532.1 - 2.5e-26 90.6 16.6 1.4e-08 34.1 0.6 3.6 3 0 0 3 3 3 3 RPEL repeat Rotamase_3 PF13616.6 KUM56532.1 - 0.087 13.4 0.6 0.39 11.3 0.1 1.9 1 1 1 2 2 2 0 PPIC-type PPIASE domain PIN_4 PF13638.6 KUM56533.1 - 1.6e-05 25.2 0.1 0.0036 17.6 0.0 2.4 2 0 0 2 2 2 2 PIN domain OAD_gamma PF04277.13 KUM56534.1 - 1.1 9.9 6.9 1.2 9.7 6.9 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain O-ag_pol_Wzy PF14296.6 KUM56534.1 - 3.3 6.3 5.1 3.1 6.4 5.1 1.0 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy SR-25 PF10500.9 KUM56534.1 - 3.5 7.2 27.5 3.9 7.0 27.5 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Connexin PF00029.19 KUM56534.1 - 4.2 7.0 6.1 4.2 7.0 6.1 1.0 1 0 0 1 1 1 0 Connexin DUF3464 PF11947.8 KUM56534.1 - 4.4 7.0 10.0 4.6 7.0 10.0 1.0 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF3899 PF13038.6 KUM56534.1 - 5.3 7.6 5.8 5.2 7.6 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Med19 PF10278.9 KUM56534.1 - 8.5 6.3 25.7 9.4 6.1 25.7 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Coilin_N PF15862.5 KUM56534.1 - 9.7 6.0 15.8 10 5.9 15.8 1.1 1 0 0 1 1 1 0 Coilin N-terminus PagL PF09411.10 KUM56536.1 - 0.0063 16.7 0.2 0.013 15.6 0.2 1.6 1 1 0 1 1 1 1 Lipid A 3-O-deacylase (PagL) DUF3824 PF12868.7 KUM56536.1 - 0.84 10.3 7.0 1.3 9.7 7.0 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Clr5 PF14420.6 KUM56537.1 - 8.1e-13 48.4 2.0 1.4e-12 47.6 2.0 1.4 1 0 0 1 1 1 1 Clr5 domain c-SKI_SMAD_bind PF08782.10 KUM56537.1 - 0.13 12.5 0.5 0.28 11.4 0.5 1.5 1 0 0 1 1 1 0 c-SKI Smad4 binding domain ADH_zinc_N PF00107.26 KUM56538.1 - 1.8e-28 99.1 1.3 3.1e-28 98.4 1.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM56538.1 - 5.9e-10 40.3 0.0 1e-09 39.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM56538.1 - 3.4e-06 26.9 0.0 2.7e-05 24.0 0.0 2.5 3 1 1 4 4 4 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KUM56538.1 - 0.0035 16.7 1.0 0.0066 15.8 1.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KUM56538.1 - 0.0092 16.2 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Glyco_tranf_2_3 PF13641.6 KUM56539.1 - 3.9e-31 108.7 0.1 4.8e-31 108.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KUM56539.1 - 2.9e-06 27.2 0.0 5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KUM56539.1 - 4e-06 26.4 0.0 0.0024 17.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 DUF2244 PF10003.9 KUM56540.1 - 0.037 13.7 0.3 0.083 12.6 0.3 1.5 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) ATP12 PF07542.11 KUM56541.1 - 9.5e-44 148.6 1.5 1e-43 148.5 0.4 1.6 2 0 0 2 2 2 1 ATP12 chaperone protein Syja_N PF02383.18 KUM56543.1 - 2.8e-82 276.6 0.0 4.6e-82 275.9 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Tti2 PF10521.9 KUM56544.1 - 7.3e-93 311.1 1.1 1.1e-92 310.6 1.1 1.3 1 0 0 1 1 1 1 Tti2 family SPATA9 PF15824.5 KUM56544.1 - 0.11 11.8 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 Pex2_Pex12 PF04757.14 KUM56545.1 - 2.9e-54 184.1 2.9 3.7e-54 183.7 2.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KUM56545.1 - 3.3e-05 23.9 2.2 5.8e-05 23.2 2.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KUM56545.1 - 0.00068 19.4 3.6 0.00091 19.0 2.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KUM56545.1 - 0.0045 16.8 1.9 0.0078 16.0 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KUM56545.1 - 0.0064 16.8 2.4 0.013 15.8 2.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KUM56545.1 - 0.021 14.7 1.6 0.037 13.9 1.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KUM56545.1 - 0.033 14.2 2.3 0.033 14.2 2.3 1.8 2 0 0 2 2 2 0 RING-type zinc-finger PIN_2 PF10130.9 KUM56546.1 - 0.034 14.4 0.0 0.045 14.0 0.0 1.2 1 0 0 1 1 1 0 PIN domain DUF520 PF04461.13 KUM56546.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF520) RsfS PF02410.15 KUM56547.1 - 5e-12 46.1 0.0 9.9e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation PolyA_pol PF01743.20 KUM56548.1 - 1.5e-21 77.1 1.3 7.9e-21 74.8 1.3 2.1 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KUM56548.1 - 2e-07 30.7 0.1 4.9e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KUM56548.1 - 0.0024 17.9 0.2 0.007 16.4 0.1 1.9 2 0 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative TRAPPC-Trs85 PF12739.7 KUM56549.1 - 2.9e-112 375.6 0.1 4.3e-112 375.1 0.1 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Bac_luciferase PF00296.20 KUM56550.1 - 6e-56 190.2 0.1 9.7e-56 189.5 0.1 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase SSF PF00474.17 KUM56551.1 - 7e-24 84.4 31.5 1.1e-23 83.8 31.5 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF5394 PF17372.2 KUM56551.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5394) FAD_binding_4 PF01565.23 KUM56552.1 - 9.9e-22 77.2 0.0 1.5e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KUM56552.1 - 4.3e-06 26.7 0.1 1.3e-05 25.2 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like DUF2207 PF09972.9 KUM56554.1 - 0.0011 17.9 0.1 0.0011 17.9 0.1 2.6 3 1 0 3 3 3 1 Predicted membrane protein (DUF2207) DUF975 PF06161.11 KUM56554.1 - 0.15 11.9 6.4 0.034 13.9 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF975) SLC3A2_N PF16028.5 KUM56554.1 - 9.7 5.8 6.7 8.9 6.0 0.1 3.0 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus Sugar_tr PF00083.24 KUM56555.1 - 2.4e-61 208.0 29.6 3e-61 207.7 29.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM56555.1 - 1.9e-17 63.2 40.0 1.9e-17 63.2 40.0 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 KUM56555.1 - 0.0041 15.7 4.8 0.0041 15.7 4.8 3.9 2 2 2 4 4 4 3 MFS/sugar transport protein RhodobacterPufX PF11511.8 KUM56555.1 - 0.065 12.8 0.2 0.065 12.8 0.2 3.0 3 0 0 3 3 3 0 Intrinsic membrane protein PufX DUF3431 PF11913.8 KUM56556.1 - 1.8e-82 276.3 0.0 2.3e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) ADH_N PF08240.12 KUM56557.1 - 3.5e-05 23.6 0.0 7.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM56557.1 - 0.067 13.2 0.2 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase 2OG-FeII_Oxy_2 PF13532.6 KUM56558.1 - 3.7e-27 95.8 0.0 7e-27 94.9 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KUM56560.1 - 1.4e-27 96.6 32.8 1.4e-27 96.6 32.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM56560.1 - 8.1e-05 21.2 3.7 8.1e-05 21.2 3.7 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MtrF PF09472.10 KUM56560.1 - 0.6 9.5 2.5 0.62 9.5 0.1 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) TraL PF07178.11 KUM56560.1 - 4.1 7.9 7.0 8.9 6.9 2.3 3.5 3 0 0 3 3 3 0 TraL protein Kinesin PF00225.23 KUM56563.1 - 6.4e-116 386.9 0.3 2.6e-115 384.9 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KUM56563.1 - 1.4e-26 93.2 0.0 3.2e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding AAA_33 PF13671.6 KUM56563.1 - 0.015 15.5 1.1 0.2 11.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain PMSR PF01625.21 KUM56564.1 - 5.7e-14 52.6 1.4 7.4e-14 52.2 1.4 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PMSR PF01625.21 KUM56565.1 - 1.3e-27 96.9 0.1 1.5e-27 96.7 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF4627 PF15425.6 KUM56565.1 - 0.11 12.2 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4627) cNMPbd_u2 PF16643.5 KUM56568.1 - 2.2e-37 128.9 8.2 5.4e-37 127.7 8.2 1.6 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 KUM56568.1 - 1.8e-36 124.1 0.0 4.7e-22 77.9 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.6 KUM56568.1 - 3.2e-11 42.3 5.5 0.91 9.7 0.0 8.4 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.7 KUM56568.1 - 1.5e-09 37.9 2.2 0.11 12.9 0.2 6.7 6 1 2 8 8 8 4 Leucine Rich repeats (2 copies) F-box PF00646.33 KUM56568.1 - 6e-05 22.8 0.9 0.00029 20.6 0.9 2.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KUM56568.1 - 7.5e-05 22.5 0.1 0.00022 21.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KUM56568.1 - 0.00026 21.1 6.7 46 5.1 0.0 8.0 8 0 0 8 8 8 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 KUM56568.1 - 0.38 11.0 3.1 5.4 7.3 0.5 3.1 3 0 0 3 3 3 0 Ste50p, sterile alpha motif DUF3425 PF11905.8 KUM56569.1 - 5.4e-21 74.9 0.1 8.8e-21 74.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) FAD_binding_4 PF01565.23 KUM56570.1 - 4e-22 78.5 1.3 8.7e-22 77.4 1.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KUM56570.1 - 0.00092 19.3 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Aldo_ket_red PF00248.21 KUM56571.1 - 1.6e-71 240.9 0.0 1.8e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_4 PF13637.6 KUM56572.1 - 1.3e-28 99.0 0.5 1.3e-09 38.4 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KUM56572.1 - 8.9e-28 96.7 0.2 7.5e-15 55.3 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KUM56572.1 - 1.7e-22 78.8 2.1 5.7e-06 26.5 0.2 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KUM56572.1 - 4e-18 63.6 1.0 0.00055 20.2 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KUM56572.1 - 1.5e-14 53.9 1.0 1.7e-10 40.9 0.0 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KUM56572.1 - 0.0006 19.3 0.3 0.00092 18.6 0.3 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins HeLo PF14479.6 KUM56572.1 - 0.0038 17.1 1.7 0.0076 16.1 1.7 1.5 1 0 0 1 1 1 1 Prion-inhibition and propagation zf-C2H2 PF00096.26 KUM56572.1 - 0.027 14.9 0.9 0.083 13.4 0.0 2.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Syntaxin_2 PF14523.6 KUM56572.1 - 0.16 12.4 4.3 2.2 8.7 0.1 2.8 3 0 0 3 3 3 0 Syntaxin-like protein Gas_vesicle PF00741.18 KUM56572.1 - 2.3 8.5 4.4 2 8.6 0.3 2.3 2 0 0 2 2 2 0 Gas vesicle protein Flocculin_t3 PF13928.6 KUM56573.1 - 0.00037 20.9 1.1 0.00037 20.9 1.1 3.1 2 1 1 3 3 3 1 Flocculin type 3 repeat MOSC PF03473.17 KUM56574.1 - 2.7e-34 118.0 0.0 4e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KUM56574.1 - 8.9e-13 48.2 0.0 1.8e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain SHMT PF00464.19 KUM56575.1 - 1.1e-198 659.7 0.0 1.3e-198 659.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 KUM56575.1 - 0.14 11.4 0.0 0.31 10.3 0.0 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Mg_trans_NIPA PF05653.14 KUM56576.1 - 4.6e-90 301.7 26.5 6.5e-90 301.2 26.5 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KUM56576.1 - 2.5e-05 24.5 5.9 2.5e-05 24.5 5.9 3.3 3 0 0 3 3 3 2 EamA-like transporter family DUF1894 PF08979.11 KUM56576.1 - 0.11 12.8 0.1 6.7 7.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1894) DUF805 PF05656.14 KUM56576.1 - 2.1 8.8 11.5 2.2 8.7 2.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Patatin PF01734.22 KUM56577.1 - 2e-15 57.5 0.0 5.6e-15 56.1 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase KilA-N PF04383.13 KUM56578.1 - 0.00029 20.7 0.1 0.0089 15.9 0.0 2.6 2 1 0 2 2 2 1 KilA-N domain BRCT_2 PF16589.5 KUM56579.1 - 2.1e-05 24.8 0.0 5.4e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KUM56579.1 - 0.0038 17.1 1.0 0.074 13.0 0.0 2.3 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 KUM56579.1 - 0.0039 17.5 0.0 0.012 15.9 0.0 1.8 1 1 0 1 1 1 1 DNA ligase 3 BRCT domain AMP-binding PF00501.28 KUM56580.1 - 1.9e-60 204.7 0.0 2.8e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KUM56580.1 - 1.8e-12 47.4 0.0 4.1e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 KUM56580.1 - 5.6e-12 44.9 11.3 2.4e-05 23.9 0.1 6.8 7 0 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KUM56580.1 - 1.5e-06 27.8 12.5 2.6 7.9 0.1 6.1 6 0 0 6 6 6 4 Hexapeptide repeat of succinyl-transferase GH3 PF03321.13 KUM56580.1 - 0.12 11.2 0.0 1.1 8.0 0.1 2.0 2 0 0 2 2 2 0 GH3 auxin-responsive promoter SnoaL_4 PF13577.6 KUM56581.1 - 7.1e-20 71.4 0.2 8.2e-20 71.2 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF1993 PF09351.10 KUM56582.1 - 1.6e-52 177.9 0.0 1.8e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) NUC202 PF08166.12 KUM56587.1 - 0.041 14.0 0.1 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 NUC202 domain AMP-binding PF00501.28 KUM56588.1 - 7.4e-75 252.1 0.0 1.2e-74 251.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KUM56588.1 - 4.7e-65 220.1 0.0 6.4e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.12 KUM56588.1 - 9.2e-36 123.3 0.0 6.6e-35 120.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KUM56588.1 - 2.8e-14 53.2 0.0 6.5e-14 52.0 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KUM56588.1 - 8.4e-09 35.7 0.1 4e-08 33.5 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KUM56588.1 - 2.5e-07 30.0 0.0 4.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KUM56588.1 - 0.0018 18.2 0.0 0.0057 16.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding AMP-binding_C PF13193.6 KUM56588.1 - 0.0036 18.3 0.0 0.0077 17.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 KUM56588.1 - 0.006 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KUM56588.1 - 0.078 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KUM56589.1 - 4.5e-11 42.8 0.0 9.1e-11 41.9 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ketoacyl-synt PF00109.26 KUM56590.1 - 9.3e-75 251.5 0.0 2.1e-74 250.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KUM56590.1 - 1.3e-56 192.0 0.0 4.5e-56 190.3 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KUM56590.1 - 7.7e-41 140.6 0.1 1.2e-40 139.9 0.1 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KUM56590.1 - 9.5e-31 106.3 0.0 2.2e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KUM56590.1 - 8.3e-12 45.6 0.0 2.4e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KUM56590.1 - 6.2e-06 25.8 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain SAT PF16073.5 KUM56590.1 - 2.4e-05 24.2 1.1 0.0027 17.5 1.1 3.2 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis KR PF08659.10 KUM56592.1 - 4.6e-52 176.6 0.0 7.3e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KUM56592.1 - 1.7e-13 50.5 0.0 2.8e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 KUM56592.1 - 9.4e-06 25.9 0.1 8.3e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KUM56592.1 - 2.5e-05 24.0 0.0 4.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Zn_clus PF00172.18 KUM56594.1 - 1.1e-07 31.8 10.9 1.6e-07 31.3 10.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Laminin_G_3 PF13385.6 KUM56596.1 - 7.6e-05 22.9 0.1 0.00019 21.6 0.1 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily KSHV_K1 PF11049.8 KUM56596.1 - 0.13 12.3 0.2 0.33 10.9 0.2 1.7 1 0 0 1 1 1 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus Aminotran_1_2 PF00155.21 KUM56599.1 - 2.1e-76 257.5 0.0 2.3e-76 257.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II adh_short PF00106.25 KUM56600.1 - 1.2e-28 99.9 0.0 1.6e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM56600.1 - 1.1e-20 74.2 0.0 1.4e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM56600.1 - 3.9e-08 33.4 0.0 8.5e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KUM56600.1 - 0.00022 21.2 0.0 0.00085 19.3 0.0 1.9 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KUM56600.1 - 0.0015 18.0 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM56600.1 - 0.0026 17.2 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sigma54_activ_2 PF14532.6 KUM56600.1 - 0.045 13.9 0.0 0.1 12.7 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain UPRTase PF14681.6 KUM56600.1 - 0.16 11.4 0.1 0.24 10.8 0.1 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Polysacc_synt_2 PF02719.15 KUM56600.1 - 0.18 10.9 0.0 1 8.4 0.0 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein RraA-like PF03737.15 KUM56601.1 - 4.5e-63 211.9 12.1 1.6e-34 119.2 4.4 2.1 2 0 0 2 2 2 2 Aldolase/RraA Osmo_CC PF08946.10 KUM56602.1 - 0.033 14.4 1.8 0.067 13.5 1.8 1.4 1 0 0 1 1 1 0 Osmosensory transporter coiled coil TraT PF05818.12 KUM56602.1 - 0.033 13.9 1.1 0.045 13.5 0.0 1.6 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Glyco_hydro_61 PF03443.14 KUM56605.1 - 1.6e-47 162.1 0.1 2.3e-47 161.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fmp27 PF10344.9 KUM56607.1 - 8.5e-246 818.2 0.0 8.5e-246 818.2 0.0 2.6 3 0 0 3 3 3 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 KUM56607.1 - 3.4e-191 636.3 0.1 3.4e-191 636.3 0.1 4.3 4 0 0 4 4 4 2 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KUM56607.1 - 3e-171 570.5 10.5 3e-171 570.5 10.5 2.3 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 KUM56607.1 - 1.4e-55 187.7 0.0 4.3e-55 186.1 0.0 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KUM56607.1 - 2.7e-55 186.6 0.1 5.9e-55 185.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KUM56607.1 - 5.2e-30 104.2 0.0 1.3e-28 99.7 0.0 3.5 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain Menin PF05053.13 KUM56607.1 - 3.1 6.1 7.6 6.9 4.9 7.6 1.6 1 0 0 1 1 1 0 Menin LysM PF01476.20 KUM56608.1 - 2.6e-11 43.4 0.5 0.001 19.1 0.1 3.2 3 0 0 3 3 3 3 LysM domain UPF0203 PF05254.12 KUM56608.1 - 2.3 8.5 12.8 4.1 7.7 1.4 4.0 3 2 0 3 3 3 0 Uncharacterised protein family (UPF0203) Ldh_2 PF02615.14 KUM56609.1 - 0.077 12.1 0.4 0.11 11.6 0.4 1.1 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase adh_short PF00106.25 KUM56610.1 - 8.7e-38 129.7 0.1 1.2e-37 129.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM56610.1 - 1.3e-30 106.7 0.1 1.6e-30 106.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM56610.1 - 1.4e-11 44.6 0.1 2e-11 44.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM56610.1 - 4.9e-06 26.2 0.0 6.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KUM56610.1 - 0.00074 19.0 0.0 0.00095 18.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 KUM56610.1 - 0.099 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KUM56610.1 - 0.24 10.9 1.2 0.24 10.9 0.2 1.5 2 0 0 2 2 2 0 NmrA-like family Glyco_hydro_18 PF00704.28 KUM56611.1 - 3.4e-48 165.0 2.7 6.5e-48 164.1 2.7 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.6 KUM56611.1 - 2.5e-19 69.5 1.3 1e-18 67.5 0.3 2.8 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.20 KUM56611.1 - 8.3e-08 32.2 0.1 0.00032 20.7 0.0 3.9 4 0 0 4 4 4 2 LysM domain Chitin_bind_1 PF00187.19 KUM56611.1 - 1.5e-05 25.4 8.5 1.5e-05 25.4 8.5 4.2 3 0 0 3 3 3 1 Chitin recognition protein 2OG-FeII_Oxy_3 PF13640.6 KUM56613.1 - 2.3e-07 31.6 0.0 3.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.24 KUM56614.1 - 2.4e-92 310.2 30.5 3e-92 309.8 30.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM56614.1 - 7.7e-23 81.0 35.1 7.7e-23 81.0 35.1 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM56614.1 - 0.00012 20.7 3.9 0.00012 20.7 3.9 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) KleE PF17394.2 KUM56615.1 - 0.086 13.1 4.4 0.042 14.1 2.0 1.8 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein ADH_N PF08240.12 KUM56616.1 - 6.6e-18 64.6 5.2 1.2e-17 63.8 5.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM56616.1 - 8.2e-12 45.2 0.0 1.4e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KUM56616.1 - 0.0004 19.8 0.1 0.0007 19.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KUM56616.1 - 0.0014 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Totivirus_coat PF05518.11 KUM56617.1 - 2.2 6.2 4.0 2.9 5.8 4.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein IQ PF00612.27 KUM56618.1 - 0.0011 18.5 0.7 0.0032 17.1 0.7 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Thiolase_N PF00108.23 KUM56619.1 - 6.5e-11 42.1 0.1 2.5e-09 36.9 0.1 2.3 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KUM56619.1 - 1.2e-10 41.1 1.4 1.7e-09 37.4 0.0 2.9 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KUM56619.1 - 1.2e-06 28.3 0.0 6.7e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KUM56619.1 - 0.00025 20.7 0.4 0.00059 19.5 0.4 1.6 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 KUM56619.1 - 0.0028 16.4 0.0 0.0057 15.4 0.0 1.4 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) GFA PF04828.14 KUM56620.1 - 4.3e-11 43.0 0.1 6.9e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme EF-hand_13 PF17958.1 KUM56621.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain DUF1082 PF06449.11 KUM56624.1 - 0.14 12.0 0.2 0.32 10.8 0.2 1.7 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1082) Hemerythrin PF01814.23 KUM56626.1 - 4.2e-13 50.0 1.2 5.7e-09 36.7 0.1 1.8 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain Sds3 PF08598.11 KUM56627.1 - 6.5e-42 144.0 3.9 1.1e-40 140.0 3.9 2.0 1 1 0 1 1 1 1 Sds3-like CMD PF02627.20 KUM56630.1 - 5.4e-18 64.8 0.1 8.9e-18 64.1 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Cohesin_HEAT PF12765.7 KUM56630.1 - 0.16 12.3 0.0 2.6 8.4 0.0 2.3 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion TraC PF07820.12 KUM56630.1 - 0.18 12.2 0.2 0.74 10.2 0.0 1.9 2 0 0 2 2 2 0 TraC-like protein NAD_binding_9 PF13454.6 KUM56632.1 - 4.1e-44 150.3 0.0 7.9e-44 149.4 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Dynactin PF12455.8 KUM56633.1 - 0.086 12.1 0.2 0.097 11.9 0.2 1.0 1 0 0 1 1 1 0 Dynein associated protein Zn_clus PF00172.18 KUM56634.1 - 7.1e-07 29.2 10.3 7.1e-07 29.2 10.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM56634.1 - 1.1e-05 24.5 0.1 1.5e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 KUM56635.1 - 6.6e-73 245.7 0.0 9.5e-73 245.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KUM56635.1 - 2.1e-34 118.8 0.0 4.3e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding_C PF13193.6 KUM56635.1 - 1.1e-06 29.5 0.0 4.7e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 KUM56635.1 - 1.6e-06 27.8 0.0 3.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KUM56635.1 - 0.00033 21.0 0.0 0.0011 19.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Pyridoxal_deC PF00282.19 KUM56636.1 - 8.7e-32 110.2 0.0 1.1e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KUM56636.1 - 4.1e-05 22.7 0.0 5.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Ank_2 PF12796.7 KUM56637.1 - 1.1e-38 131.6 10.7 1.6e-12 47.9 0.2 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KUM56637.1 - 1.6e-30 101.7 0.6 0.00087 19.6 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 KUM56637.1 - 4.5e-30 102.7 3.4 0.00073 19.9 0.2 8.3 7 1 1 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 KUM56637.1 - 4.9e-29 100.3 6.2 5.6e-07 30.0 0.3 5.8 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM56637.1 - 8e-23 80.2 8.3 3.3e-06 27.2 0.1 6.8 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Spc29 PF17082.5 KUM56639.1 - 0.0033 17.3 0.2 0.0042 17.0 0.2 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 PLC-beta_C PF08703.10 KUM56639.1 - 0.01 15.9 1.6 0.013 15.5 1.6 1.1 1 0 0 1 1 1 0 PLC-beta C terminal Fez1 PF06818.15 KUM56639.1 - 0.01 16.3 0.4 0.013 15.9 0.4 1.1 1 0 0 1 1 1 0 Fez1 CCDC106 PF15794.5 KUM56639.1 - 0.024 14.3 0.8 0.033 13.9 0.2 1.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 HEPN_AbiU2 PF18734.1 KUM56639.1 - 0.039 13.4 0.1 0.078 12.5 0.0 1.5 1 1 0 1 1 1 0 AbiU2 Gag_p17 PF00540.18 KUM56639.1 - 0.042 13.9 0.1 0.055 13.5 0.1 1.2 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) DUF4527 PF15030.6 KUM56639.1 - 0.042 13.3 0.1 0.048 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) DUF684 PF05075.14 KUM56639.1 - 0.054 12.5 0.3 0.066 12.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF684) YabA PF06156.13 KUM56639.1 - 0.11 13.2 0.6 0.14 12.8 0.6 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 KUM56639.1 - 0.22 11.3 2.9 0.32 10.8 2.9 1.2 1 0 0 1 1 1 0 Septum formation initiator Fungal_trans_2 PF11951.8 KUM56640.1 - 0.0021 16.9 2.2 0.0029 16.5 2.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain His_Phos_2 PF00328.22 KUM56641.1 - 1.7e-21 77.0 0.0 4e-21 75.8 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Acetyltransf_10 PF13673.7 KUM56643.1 - 1.8e-08 34.4 0.0 2.8e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM56643.1 - 5.2e-07 29.9 0.0 7.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KUM56643.1 - 4.7e-06 26.9 0.0 7.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KUM56643.1 - 0.00023 21.2 0.0 0.0035 17.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KUM56643.1 - 0.0011 19.1 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KUM56643.1 - 0.0057 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein SQHop_cyclase_N PF13249.6 KUM56643.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Squalene-hopene cyclase N-terminal domain MFS_1 PF07690.16 KUM56645.1 - 6e-20 71.5 13.9 7.1e-20 71.2 13.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3961 PF13106.6 KUM56645.1 - 0.19 11.4 3.1 6.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) Sugar_tr PF00083.24 KUM56646.1 - 1.3e-143 479.2 27.0 1.5e-143 479.0 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM56646.1 - 8.2e-23 80.9 35.5 1.8e-16 60.0 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_75 PF07335.11 KUM56647.1 - 4e-19 69.5 0.1 5.4e-19 69.1 0.1 1.2 1 1 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Herpes_capsid PF06112.11 KUM56647.1 - 7.3 6.6 14.7 9.6 6.2 14.7 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein CBM_1 PF00734.18 KUM56648.1 - 1.2e-11 44.4 11.3 2.6e-11 43.3 11.3 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Carboxyl_trans PF01039.22 KUM56649.1 - 2.2e-137 458.7 0.0 2.6e-137 458.5 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Acyl-CoA_dh_1 PF00441.24 KUM56653.1 - 1.8e-40 138.6 1.0 2.9e-40 137.9 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KUM56653.1 - 2.6e-32 111.8 0.1 4.8e-32 111.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KUM56653.1 - 2.1e-22 79.1 0.1 4.2e-10 39.7 0.1 2.6 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KUM56653.1 - 2.9e-15 56.7 0.1 4.5e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.25 KUM56654.1 - 0.003 17.0 0.1 0.13 11.6 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain CPSase_L_D2 PF02786.17 KUM56655.1 - 1.4e-73 246.9 0.0 2.9e-73 245.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KUM56655.1 - 1.6e-37 127.9 0.0 4.1e-37 126.6 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KUM56655.1 - 7e-36 123.1 0.0 1.4e-35 122.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KUM56655.1 - 8.1e-18 64.0 0.4 2.7e-17 62.4 0.3 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KUM56655.1 - 1.5e-09 37.7 0.0 3.9e-09 36.3 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KUM56655.1 - 1.5e-05 24.7 0.1 0.028 14.2 0.1 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 KUM56655.1 - 7.2e-05 22.9 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KUM56655.1 - 0.0017 18.1 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 KUM56655.1 - 0.0077 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 KUM56655.1 - 0.008 16.9 0.0 3.1 8.5 0.0 2.8 2 0 0 2 2 2 1 HlyD family secretion protein GCV_H PF01597.19 KUM56655.1 - 0.085 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein Z1 PF10593.9 KUM56656.1 - 0.1 12.1 0.1 0.22 11.0 0.0 1.5 1 1 0 1 1 1 0 Z1 domain GMP_synt_C PF00958.22 KUM56657.1 - 5.8e-36 122.4 0.0 1.3e-35 121.3 0.0 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KUM56657.1 - 5.8e-36 124.1 0.0 1.2e-35 123.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 KUM56657.1 - 2.5e-09 36.6 0.0 8.4e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.16 KUM56657.1 - 0.00011 21.2 0.1 0.00026 19.9 0.1 1.6 2 0 0 2 2 2 1 tRNA methyl transferase PAPS_reduct PF01507.19 KUM56657.1 - 0.001 19.2 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Peptidase_C26 PF07722.13 KUM56657.1 - 0.0011 18.8 0.0 0.34 10.6 0.0 2.5 2 0 0 2 2 2 2 Peptidase C26 Arginosuc_synth PF00764.19 KUM56657.1 - 0.002 17.5 0.1 0.0028 17.0 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KUM56657.1 - 0.013 15.0 0.0 0.084 12.4 0.0 2.0 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ThiI PF02568.14 KUM56657.1 - 0.039 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) PDCD2_C PF04194.13 KUM56658.1 - 9.6e-41 139.8 0.0 5.3e-40 137.3 0.0 2.0 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain A2L_zn_ribbon PF08792.10 KUM56658.1 - 0.12 12.1 0.3 7.5 6.4 0.1 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain PC-Esterase PF13839.6 KUM56659.1 - 0.086 12.6 0.0 0.088 12.5 0.0 1.1 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p GRAM PF02893.20 KUM56660.1 - 2.5e-34 117.6 1.7 3.4e-23 81.7 0.1 3.3 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 KUM56660.1 - 3.7e-26 91.8 0.0 7.6e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 KUM56660.1 - 5.9e-16 58.9 0.0 1.1e-14 54.7 0.0 2.8 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 KUM56660.1 - 3.2e-06 27.5 0.8 8.9e-05 22.9 0.8 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KUM56660.1 - 0.00011 22.2 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KUM56660.1 - 0.00038 20.7 0.0 0.00095 19.4 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DUF4288 PF14119.6 KUM56660.1 - 0.024 15.0 0.4 0.073 13.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) UDPGT PF00201.18 KUM56660.1 - 0.03 13.1 0.0 0.053 12.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Spc7 PF08317.11 KUM56662.1 - 0.00063 18.7 7.8 0.00085 18.3 7.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Prefoldin_2 PF01920.20 KUM56662.1 - 0.004 17.1 8.7 0.42 10.6 3.3 2.1 2 0 0 2 2 2 2 Prefoldin subunit DUF4140 PF13600.6 KUM56662.1 - 0.0046 17.3 1.4 0.68 10.4 0.6 2.1 1 1 1 2 2 2 1 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 KUM56662.1 - 0.0093 16.3 5.6 1.5 9.2 0.1 2.4 2 0 0 2 2 2 2 Flagella accessory protein C (FlaC) APG6_N PF17675.1 KUM56662.1 - 0.021 15.4 8.7 1 9.9 0.3 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Inj_translocase PF16928.5 KUM56662.1 - 0.022 14.2 0.2 0.023 14.1 0.2 1.2 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome HBM PF16591.5 KUM56662.1 - 0.032 13.7 4.5 0.11 11.9 3.6 1.9 1 1 0 1 1 1 0 Helical bimodular sensor domain CC2-LZ PF16516.5 KUM56662.1 - 0.067 13.6 8.7 1.5 9.2 3.6 2.1 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator SlyX PF04102.12 KUM56662.1 - 0.093 13.4 6.1 3.8 8.2 2.3 2.3 1 1 1 2 2 2 0 SlyX DUF2730 PF10805.8 KUM56662.1 - 0.12 12.5 4.4 5.7 7.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Syntaxin-6_N PF09177.11 KUM56662.1 - 0.13 12.8 3.3 3.8 8.1 3.3 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Tektin PF03148.14 KUM56662.1 - 0.14 10.8 10.5 1.4 7.6 0.4 2.0 1 1 1 2 2 2 0 Tektin family DUF4094 PF13334.6 KUM56662.1 - 0.38 11.2 4.9 3.8 8.0 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) GvpL_GvpF PF06386.11 KUM56662.1 - 0.59 10.0 3.3 0.73 9.7 3.3 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF948 PF06103.11 KUM56662.1 - 0.92 9.8 2.9 1.5 9.1 0.5 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FapA PF03961.13 KUM56662.1 - 1.1 7.8 8.9 0.77 8.3 7.5 1.4 1 1 1 2 2 2 0 Flagellar Assembly Protein A COG2 PF06148.11 KUM56662.1 - 1.3 9.1 5.7 8.4 6.5 0.4 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 EMP24_GP25L PF01105.24 KUM56662.1 - 2.4 8.0 7.9 5.5 6.9 3.5 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD YabA PF06156.13 KUM56662.1 - 3.7 8.2 9.4 1.1 9.9 1.0 2.3 1 1 1 2 2 2 0 Initiation control protein YabA TMPIT PF07851.13 KUM56662.1 - 7.2 5.8 7.9 9.1 5.4 7.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Prenylcys_lyase PF07156.14 KUM56663.1 - 3e-94 316.1 0.0 4.1e-94 315.7 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KUM56663.1 - 4.6e-13 49.2 0.0 9.8e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KUM56663.1 - 3.4e-11 43.1 0.0 1e-10 41.5 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KUM56663.1 - 1.7e-06 27.9 0.6 0.0005 19.8 0.3 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM56663.1 - 0.0011 18.3 0.1 0.074 12.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM56663.1 - 0.002 18.1 0.5 0.026 14.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KUM56663.1 - 0.028 15.0 0.1 10 6.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_3 PF07859.13 KUM56663.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold HI0933_like PF03486.14 KUM56663.1 - 0.063 12.0 0.1 0.87 8.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein ThiF PF00899.21 KUM56663.1 - 0.094 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 ThiF family Peptidase_M17_N PF02789.17 KUM56663.1 - 0.098 12.5 0.1 0.29 11.0 0.1 1.7 1 1 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain TPP_enzyme_M PF00205.22 KUM56663.1 - 0.12 12.1 0.1 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain CLP1_P PF16575.5 KUM56664.1 - 3.7e-26 92.1 0.0 7.6e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 KUM56664.1 - 0.01 16.2 0.0 3.4 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KUM56664.1 - 0.04 14.1 2.4 0.096 12.9 0.0 2.7 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KUM56664.1 - 0.058 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KUM56664.1 - 0.092 13.3 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 KUM56664.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein G-alpha PF00503.20 KUM56664.1 - 0.2 10.7 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit RNA_polI_A34 PF08208.11 KUM56665.1 - 1.3e-43 149.5 17.7 1.3e-43 149.5 17.7 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF2052 PF09747.9 KUM56665.1 - 2.4 8.2 18.1 3.9 7.5 1.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Prefoldin PF02996.17 KUM56667.1 - 3.9e-12 46.1 0.1 4.9e-12 45.8 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KUM56667.1 - 0.0036 17.2 0.1 0.0047 16.9 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit End3 PF12761.7 KUM56667.1 - 0.035 14.3 0.1 0.038 14.2 0.1 1.2 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 FlaC_arch PF05377.11 KUM56667.1 - 0.11 12.9 0.2 0.15 12.5 0.2 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) S1-P1_nuclease PF02265.16 KUM56668.1 - 3.4e-67 226.9 0.1 4e-67 226.7 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Endotoxin_mid PF09131.10 KUM56668.1 - 0.068 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacillus thuringiensis delta-Endotoxin, middle domain NmrA PF05368.13 KUM56669.1 - 0.0002 21.0 0.0 0.00024 20.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family ETF PF01012.21 KUM56670.1 - 3.6e-44 150.8 2.7 5.7e-44 150.2 2.1 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KUM56670.1 - 1.5e-32 111.5 0.1 3.2e-32 110.4 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain GST_N PF02798.20 KUM56671.1 - 1.3e-14 54.3 0.1 2.6e-13 50.1 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KUM56671.1 - 2e-14 53.6 0.0 3.2e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KUM56671.1 - 8.2e-14 51.8 0.0 1.4e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KUM56671.1 - 2.7e-11 43.6 0.0 4.9e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KUM56671.1 - 2.4e-10 40.5 0.0 4.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KUM56671.1 - 1.2e-06 28.4 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AAA PF00004.29 KUM56672.1 - 3.2e-11 43.8 0.0 9.4e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KUM56672.1 - 6.4e-06 26.5 0.0 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KUM56672.1 - 5.8e-05 23.1 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KUM56672.1 - 9.7e-05 22.2 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KUM56672.1 - 0.0017 18.3 0.0 0.0059 16.5 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 KUM56672.1 - 0.0026 18.0 0.0 0.0075 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KUM56672.1 - 0.0048 17.3 0.1 0.041 14.3 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KUM56672.1 - 0.0082 16.1 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_14 PF13173.6 KUM56672.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KUM56672.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KUM56672.1 - 0.12 11.9 0.0 0.84 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KUM56672.1 - 0.15 12.6 0.0 0.42 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KUM56672.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RXT2_N PF08595.11 KUM56672.1 - 1.6 8.7 4.6 1.2 9.2 0.3 2.6 3 0 0 3 3 3 0 RXT2-like, N-terminal Ribosomal_L1 PF00687.21 KUM56673.1 - 2.3e-60 203.8 5.2 3.9e-60 203.1 5.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family PH_5 PF15405.6 KUM56673.1 - 1.9 8.6 6.8 0.2 11.7 0.2 2.5 3 0 0 3 3 3 0 Pleckstrin homology domain SSP160 PF06933.11 KUM56674.1 - 5.8 5.0 13.4 6 4.9 13.4 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4621 PF15414.6 KUM56676.1 - 0.0039 16.1 0.0 0.005 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4621) Ceramidase_alk PF04734.13 KUM56676.1 - 0.0079 14.9 0.1 0.01 14.5 0.1 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal EMC3_TMCO1 PF01956.16 KUM56677.1 - 0.31 10.7 5.9 5.8 6.6 0.1 2.6 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF2721 PF11026.8 KUM56677.1 - 0.57 10.1 7.8 8 6.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) AA_permease_2 PF13520.6 KUM56678.1 - 3.2e-43 148.2 52.2 4e-43 147.8 52.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM56678.1 - 9.7e-16 57.4 45.8 1.4e-15 56.9 45.8 1.1 1 0 0 1 1 1 1 Amino acid permease SNF2_N PF00176.23 KUM56680.1 - 2.8e-56 190.7 0.0 4.3e-56 190.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KUM56680.1 - 1.3e-15 57.7 0.0 2.5e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM56680.1 - 6e-11 42.7 0.0 5.1e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KUM56680.1 - 0.00028 20.7 0.0 0.00053 19.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KUM56680.1 - 0.0042 16.3 0.0 0.013 14.7 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KUM56680.1 - 0.059 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase CVNH PF08881.10 KUM56681.1 - 3.4e-28 98.3 0.1 3.7e-28 98.2 0.1 1.0 1 0 0 1 1 1 1 CVNH domain PfkB PF00294.24 KUM56682.1 - 3.5e-32 111.9 0.0 6.3e-32 111.1 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase p6 PF17548.2 KUM56682.1 - 0.1 12.6 0.0 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Histone-like Protein p6 RNase_H PF00075.24 KUM56683.1 - 0.00026 21.2 0.1 0.0042 17.3 0.1 2.2 1 1 0 1 1 1 1 RNase H DUF3971 PF13116.6 KUM56683.1 - 0.0011 18.7 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function Cwf_Cwc_15 PF04889.12 KUM56685.1 - 0.058 13.1 11.9 0.077 12.7 11.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 KUM56685.1 - 0.23 11.3 8.8 0.32 10.8 8.8 1.3 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing RNase_H PF00075.24 KUM56687.1 - 0.049 13.8 0.1 0.11 12.7 0.1 1.7 1 1 0 1 1 1 0 RNase H PEPcase PF00311.17 KUM56689.1 - 0.051 11.6 0.1 0.053 11.6 0.1 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase DUF1690 PF07956.11 KUM56689.1 - 0.089 13.2 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) FA_desaturase PF00487.24 KUM56690.1 - 3.9e-18 66.2 14.5 4.7e-18 65.9 14.5 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Glyco_hydro_3 PF00933.21 KUM56691.1 - 2.7e-60 204.4 0.0 3.2e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Cation_efflux PF01545.21 KUM56692.1 - 4.2e-34 118.0 0.1 4.6e-34 117.9 0.1 1.0 1 0 0 1 1 1 1 Cation efflux family DUF1929 PF09118.11 KUM56694.1 - 1.1e-24 86.5 0.1 1.8e-24 85.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KUM56694.1 - 1.5e-05 24.9 0.0 0.00012 22.0 0.0 2.2 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.25 KUM56694.1 - 0.0014 18.2 0.0 0.003 17.1 0.0 1.6 1 0 0 1 1 1 1 Kelch motif Kelch_6 PF13964.6 KUM56694.1 - 0.013 15.7 0.0 0.033 14.5 0.0 1.8 1 0 0 1 1 1 0 Kelch motif DUF1593 PF07632.11 KUM56695.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) Abhydro_lipase PF04083.16 KUM56696.1 - 5.9e-21 73.8 0.0 1.1e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KUM56696.1 - 1e-06 28.6 0.1 2.3e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM56696.1 - 0.016 14.4 0.0 0.043 13.1 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KUM56696.1 - 0.046 12.6 0.0 0.23 10.3 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase enzyme MFS_1 PF07690.16 KUM56697.1 - 1.8e-37 129.1 53.7 9.2e-36 123.5 49.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1418 PF07214.12 KUM56697.1 - 0.33 10.8 0.0 0.33 10.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) Pirin PF02678.16 KUM56699.1 - 1.1e-23 83.3 0.7 3e-23 81.9 0.7 1.7 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KUM56699.1 - 2.5e-06 27.1 1.8 0.00054 19.6 0.2 3.3 3 1 0 3 3 3 2 Cupin domain MelC1 PF06236.11 KUM56699.1 - 0.022 14.8 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 Aa_trans PF01490.18 KUM56701.1 - 1.1e-43 149.5 24.2 1.3e-43 149.3 24.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4134 PF13572.6 KUM56701.1 - 0.016 15.5 0.1 0.016 15.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4134) DUF1180 PF06679.12 KUM56703.1 - 2.6 8.4 5.7 2.7 8.4 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) VRR_NUC PF08774.11 KUM56704.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 VRR-NUC domain Acyl_transf_1 PF00698.21 KUM56706.1 - 1.3e-19 70.8 0.9 1.6e-19 70.6 0.9 1.1 1 0 0 1 1 1 1 Acyl transferase domain TMEM126 PF07114.11 KUM56706.1 - 0.009 15.4 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 126 PS-DH PF14765.6 KUM56707.1 - 4.7e-61 206.6 0.1 8.8e-61 205.7 0.0 1.5 2 0 0 2 2 2 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 KUM56707.1 - 2.3e-05 25.1 0.0 6.8e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Acyl_transf_1 PF00698.21 KUM56707.1 - 4.3e-05 23.2 0.0 6.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_25 PF13649.6 KUM56707.1 - 0.0014 19.3 0.0 0.0044 17.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KUM56707.1 - 0.087 11.9 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_28 PF02636.17 KUM56707.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Cutinase PF01083.22 KUM56708.1 - 2.4e-48 164.4 2.2 2.8e-48 164.2 2.2 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KUM56708.1 - 0.00034 20.6 0.0 0.00069 19.6 0.0 1.5 2 0 0 2 2 2 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 KUM56708.1 - 0.0012 18.4 0.1 0.0019 17.8 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Pec_lyase_C PF00544.19 KUM56709.1 - 4.7e-15 55.8 7.0 5e-14 52.4 7.0 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KUM56709.1 - 0.0009 19.1 13.0 0.21 11.4 3.8 2.3 1 1 1 2 2 2 2 Right handed beta helix region HD PF01966.22 KUM56710.1 - 0.0001 22.5 0.0 0.00027 21.2 0.0 1.8 1 1 0 1 1 1 1 HD domain Pec_lyase_C PF00544.19 KUM56711.1 - 2.5e-16 59.9 12.0 2.4e-15 56.7 12.0 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KUM56711.1 - 0.00038 20.3 15.4 0.0014 18.5 0.8 2.4 1 1 0 2 2 2 2 Right handed beta helix region LOR PF04525.12 KUM56712.1 - 4.2e-07 29.8 0.1 3.6e-06 26.7 0.1 2.2 1 1 0 1 1 1 1 LURP-one-related PALP PF00291.25 KUM56713.1 - 1.7e-36 126.1 1.0 1.9e-36 126.0 1.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RTA1 PF04479.13 KUM56714.1 - 1.9e-75 253.0 5.1 1.9e-75 253.0 5.1 1.4 2 0 0 2 2 2 1 RTA1 like protein M-factor PF03855.13 KUM56715.1 - 0.16 12.1 0.8 0.26 11.4 0.8 1.4 1 0 0 1 1 1 0 M-factor RTA1 PF04479.13 KUM56716.1 - 4.2e-70 235.6 11.4 4.2e-70 235.6 11.4 1.9 1 1 1 2 2 2 1 RTA1 like protein PalH PF08733.10 KUM56716.1 - 5 6.0 18.8 0.09 11.8 6.2 2.1 1 1 0 2 2 2 0 PalH/RIM21 HNH_2 PF13391.6 KUM56717.1 - 3.4e-06 27.1 0.0 9.8e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 HNH endonuclease GDPD PF03009.17 KUM56719.1 - 7.2e-09 35.7 0.0 1.3e-08 34.9 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KUM56719.1 - 0.022 15.2 0.0 0.044 14.2 0.0 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family LIM PF00412.22 KUM56720.1 - 3.4e-18 65.6 14.6 1.2e-10 41.5 4.1 2.4 2 0 0 2 2 2 2 LIM domain Terminase_GpA PF05876.12 KUM56720.1 - 0.07 11.7 0.8 0.1 11.1 0.8 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Cytochrom_c3_2 PF14537.6 KUM56720.1 - 0.25 11.8 9.6 28 5.3 9.6 2.4 1 1 0 1 1 1 0 Cytochrome c3 Sugar_tr PF00083.24 KUM56721.1 - 8.6e-89 298.5 25.4 1.1e-88 298.1 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM56721.1 - 7.8e-22 77.7 31.4 7.8e-22 77.7 31.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_5 PF07994.12 KUM56722.1 - 8e-144 478.9 0.0 9.6e-144 478.7 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KUM56722.1 - 1.3e-45 154.1 0.7 3.2e-45 152.8 0.7 1.7 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Fungal_trans_2 PF11951.8 KUM56723.1 - 2e-10 40.1 0.0 2.7e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM56723.1 - 1.4e-05 25.1 14.0 2.7e-05 24.2 14.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GDPD PF03009.17 KUM56724.1 - 2.2e-14 53.8 0.1 2.7e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DNA_ligase_A_M PF01068.21 KUM56727.1 - 6.9e-47 159.7 0.0 3.1e-46 157.6 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KUM56727.1 - 5.4e-46 157.1 0.1 5.4e-45 153.8 0.0 2.6 4 0 0 4 4 4 1 DNA ligase N terminus BRCT_2 PF16589.5 KUM56727.1 - 3.9e-20 72.0 0.2 1.4e-13 51.1 0.0 3.3 2 1 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KUM56727.1 - 1.5e-18 67.2 0.1 1.2e-17 64.3 0.0 2.6 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KUM56727.1 - 4.2e-17 62.9 0.0 1.2e-16 61.5 0.0 1.8 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 KUM56727.1 - 3.3e-07 30.6 0.0 0.0018 18.6 0.0 3.0 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 KUM56727.1 - 4.4e-07 29.9 0.2 9.3e-07 28.9 0.2 1.6 1 0 0 1 1 1 1 DNA ligase IV LIG3_BRCT PF16759.5 KUM56727.1 - 2.9e-06 27.5 0.1 0.021 15.1 0.0 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KUM56727.1 - 0.00038 20.3 0.0 0.046 13.6 0.1 2.4 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain mRNA_cap_enzyme PF01331.19 KUM56727.1 - 0.032 14.0 0.1 0.21 11.4 0.0 2.4 1 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain BTB PF00651.31 KUM56728.1 - 0.0025 18.0 0.0 0.0044 17.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain FAP PF07174.11 KUM56728.1 - 0.0029 17.1 1.4 0.0046 16.5 1.4 1.3 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) Draxin PF15550.6 KUM56728.1 - 0.028 14.3 2.4 0.039 13.8 2.4 1.1 1 0 0 1 1 1 0 Draxin DUF1387 PF07139.11 KUM56728.1 - 0.046 13.5 6.0 0.065 13.0 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) MFS_1 PF07690.16 KUM56730.1 - 1.6e-15 56.9 5.6 2.2e-15 56.5 5.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CRAL_TRIO PF00650.20 KUM56731.1 - 3.1e-41 140.7 0.0 6.3e-41 139.7 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KUM56731.1 - 3.9e-10 39.8 0.0 1.1e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KUM56731.1 - 2.7e-06 27.6 0.0 4.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Fungal_trans PF04082.18 KUM56732.1 - 2.9e-09 36.4 2.2 3.9e-09 35.9 2.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM56732.1 - 2.2e-08 34.1 10.3 4.4e-08 33.1 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KUM56733.1 - 1.9e-42 145.5 43.1 1.9e-42 145.5 43.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM56733.1 - 1.1e-07 30.6 19.9 1.6e-07 30.1 19.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CHB_HEX_C_1 PF13290.6 KUM56735.1 - 0.14 12.2 2.5 3.1 7.9 1.5 2.4 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain adh_short PF00106.25 KUM56737.1 - 7e-25 87.6 0.1 9.7e-25 87.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM56737.1 - 4.8e-20 72.1 0.1 6e-20 71.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM56737.1 - 4.5e-07 29.9 0.0 8.7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM56737.1 - 1e-06 28.4 0.1 1e-05 25.2 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM56737.1 - 3.2e-05 23.5 0.0 0.039 13.3 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KUM56737.1 - 0.085 12.7 0.1 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 NAD(P)H-binding DAO PF01266.24 KUM56738.1 - 1e-09 38.5 4.0 0.0013 18.4 0.8 3.0 1 1 2 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KUM56738.1 - 9.2e-08 31.7 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KUM56738.1 - 5.3e-07 29.2 0.0 0.018 14.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM56738.1 - 2.6e-05 23.5 1.7 0.0002 20.6 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KUM56738.1 - 0.00028 19.7 0.2 0.065 11.9 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 KUM56738.1 - 0.0018 17.6 0.0 0.054 12.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KUM56738.1 - 0.0055 15.6 0.6 1.6 7.5 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.7 KUM56738.1 - 0.0061 16.0 0.7 0.021 14.2 0.7 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KUM56738.1 - 0.0074 16.5 0.1 0.015 15.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KUM56738.1 - 0.0077 15.3 2.1 0.066 12.3 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 KUM56738.1 - 0.013 14.6 0.5 0.13 11.3 0.3 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KUM56738.1 - 0.11 11.8 0.2 2.5 7.3 0.1 2.1 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KUM56738.1 - 0.15 12.7 0.2 24 5.6 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TIP39 PF14980.6 KUM56738.1 - 0.59 10.1 2.4 6.3 6.8 0.2 2.6 2 0 0 2 2 2 0 TIP39 peptide Porin_3 PF01459.22 KUM56739.1 - 7.7e-82 274.8 0.1 8.9e-82 274.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.10 KUM56739.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.25 KUM56740.1 - 1.1e-66 224.9 0.0 1.3e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM56740.1 - 6.4e-25 87.9 0.0 7.8e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM56740.1 - 7.6e-06 25.4 0.0 3.4e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KUM56740.1 - 0.00098 19.1 0.3 0.02 14.8 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KUM56740.1 - 0.18 11.1 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIF4G_like PF09088.11 KUM56741.1 - 6.7e-88 293.5 0.2 1e-87 292.9 0.2 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KUM56741.1 - 7e-75 251.9 0.0 1.2e-74 251.2 0.0 1.4 1 0 0 1 1 1 1 MIF4G like DUF2326 PF10088.9 KUM56741.1 - 0.12 12.1 0.2 1.3 8.8 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein conserved in bacteria (DUF2326) DUF5448 PF17526.2 KUM56741.1 - 0.13 12.4 0.0 35 4.6 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5448) AAA_30 PF13604.6 KUM56741.1 - 0.15 11.8 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain zf-C2H2 PF00096.26 KUM56742.1 - 2.8e-19 68.4 20.5 0.00018 21.8 0.7 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KUM56742.1 - 1.1e-12 47.7 23.3 2e-08 34.3 2.3 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KUM56742.1 - 4.6e-11 42.6 18.1 0.011 16.5 0.9 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KUM56742.1 - 2.1e-05 24.8 5.0 0.0016 18.7 2.7 3.1 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KUM56742.1 - 0.00019 21.6 4.6 0.069 13.3 0.1 3.2 2 1 1 3 3 3 2 Aberrant zinc-finger zf-met PF12874.7 KUM56742.1 - 0.00091 19.5 7.8 0.07 13.6 0.4 5.0 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-DNA_Pol PF08996.10 KUM56742.1 - 0.67 9.7 7.8 1.4 8.7 1.4 2.5 2 1 1 3 3 3 0 DNA Polymerase alpha zinc finger zf-C2H2_6 PF13912.6 KUM56742.1 - 1.1 9.3 16.1 5.5 7.1 0.6 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger 6PF2K PF01591.18 KUM56743.1 - 2.2e-63 213.6 0.1 3.2e-63 213.0 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KUM56743.1 - 1.3e-19 70.6 0.5 5.8e-19 68.6 0.5 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KUM56743.1 - 0.021 15.0 0.0 0.058 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 KUM56743.1 - 0.054 12.9 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 KUM56743.1 - 0.13 12.2 0.0 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase Urm1 PF09138.11 KUM56744.1 - 2.1e-28 98.5 0.0 4.2e-28 97.6 0.0 1.4 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KUM56744.1 - 0.004 17.8 0.0 0.005 17.5 0.0 1.4 1 1 0 1 1 1 1 ThiS family WD40 PF00400.32 KUM56745.1 - 1.1e-32 111.5 23.7 3.6e-05 24.4 0.1 11.4 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM56745.1 - 5.8e-06 26.5 8.5 12 6.3 0.0 7.9 6 2 3 9 9 9 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KUM56745.1 - 3.7e-05 22.9 0.3 0.77 8.7 0.0 4.4 3 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4596 PF15363.6 KUM56745.1 - 0.1 12.9 0.7 0.4 11.0 0.7 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) DUF4165 PF13752.6 KUM56745.1 - 0.16 11.9 1.0 0.99 9.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4165) 3HCDH_N PF02737.18 KUM56747.1 - 1.7e-27 96.5 0.0 1.2e-26 93.7 0.0 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KUM56747.1 - 1.1e-11 45.2 0.0 2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain SGL PF08450.12 KUM56747.1 - 0.00069 19.3 0.2 0.68 9.5 0.0 3.1 1 1 2 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KUM56747.1 - 0.012 15.8 0.0 8.5 6.7 0.0 2.8 2 0 0 2 2 2 0 Arylesterase Pyr_redox PF00070.27 KUM56747.1 - 0.021 15.4 0.1 0.087 13.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM56747.1 - 0.022 14.0 0.1 0.044 13.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NHL PF01436.21 KUM56747.1 - 0.049 13.7 0.1 1.9 8.6 0.0 3.5 3 0 0 3 3 3 0 NHL repeat NAD_binding_2 PF03446.15 KUM56747.1 - 0.077 13.2 0.0 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ldl_recept_b PF00058.17 KUM56747.1 - 0.095 13.2 0.1 12 6.5 0.0 4.0 4 0 0 4 4 4 0 Low-density lipoprotein receptor repeat class B MFS_1 PF07690.16 KUM56748.1 - 6.1e-30 104.3 24.6 7.7e-30 104.0 24.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KUM56748.1 - 0.042 13.1 12.9 0.044 13.1 12.5 1.3 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB YwcE PF17368.2 KUM56748.1 - 0.68 10.6 0.0 0.68 10.6 0.0 3.1 4 0 0 4 4 4 0 Spore morphogenesis and germination YwcE AARP2CN PF08142.12 KUM56749.1 - 0.06 13.4 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 AARP2CN (NUC121) domain DUF5399 PF17377.2 KUM56750.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5399) GMC_oxred_N PF00732.19 KUM56751.1 - 8.6e-54 182.9 0.0 1.1e-53 182.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM56751.1 - 3.3e-32 112.0 0.2 6.5e-32 111.0 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KUM56751.1 - 6.4e-05 22.2 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KUM56751.1 - 0.0026 17.9 0.0 0.0068 16.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM56751.1 - 0.0028 17.3 0.0 0.46 10.0 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 KUM56751.1 - 0.0065 15.6 0.0 0.57 9.2 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KUM56751.1 - 0.0068 15.7 0.0 0.79 8.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM56751.1 - 0.035 13.4 0.0 0.66 9.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KUM56751.1 - 0.064 11.9 0.0 0.77 8.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Metallophos PF00149.28 KUM56753.1 - 3.1e-18 67.0 0.1 6.5e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KUM56753.1 - 2.3e-14 54.0 0.0 6.1e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KUM56753.1 - 5.3e-13 49.3 2.7 1.3e-12 48.1 2.7 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 KUM56753.1 - 0.00016 22.1 0.1 0.00037 21.0 0.1 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain ADD_DNMT3 PF17980.1 KUM56753.1 - 0.015 15.3 1.5 7.8 6.6 0.1 2.9 3 0 0 3 3 3 0 Cysteine rich ADD domain in DNMT3 Phage_holin_2_1 PF04971.12 KUM56753.1 - 0.1 12.6 0.9 0.24 11.4 0.9 1.6 1 0 0 1 1 1 0 Bacteriophage P21 holin S PhzC-PhzF PF02567.16 KUM56754.1 - 5e-39 134.5 0.0 5.7e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Amidase PF01425.21 KUM56755.1 - 2.1e-31 109.4 0.5 3.4e-31 108.7 0.5 1.2 1 0 0 1 1 1 1 Amidase DAO PF01266.24 KUM56756.1 - 1.4e-24 87.3 0.0 2.7e-24 86.4 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KUM56756.1 - 7.6e-07 29.6 0.0 5.1e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM56756.1 - 8.3e-07 28.5 0.0 0.0005 19.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM56756.1 - 8.7e-07 29.1 0.1 2.7e-06 27.5 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_2 PF03446.15 KUM56756.1 - 0.00057 20.1 0.0 0.0036 17.5 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KUM56756.1 - 0.00095 19.2 0.0 0.0024 17.9 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 KUM56756.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KUM56756.1 - 0.0057 16.7 0.1 0.32 11.0 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding ApbA PF02558.16 KUM56756.1 - 0.016 14.9 0.0 0.058 13.0 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 KUM56756.1 - 0.031 13.4 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KUM56756.1 - 0.057 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 KUM56756.1 - 0.059 12.1 0.0 0.094 11.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Glu_dehyd_C PF16912.5 KUM56756.1 - 0.094 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus F420_oxidored PF03807.17 KUM56756.1 - 0.12 12.9 0.0 8.3 7.1 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent K_oxygenase PF13434.6 KUM56756.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Adeno_PVIII PF01310.18 KUM56756.1 - 0.19 11.3 0.1 0.4 10.2 0.1 1.5 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII Amino_oxidase PF01593.24 KUM56757.1 - 2e-33 116.4 0.2 2.6e-33 116.0 0.2 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KUM56757.1 - 4.1e-06 26.9 0.0 1.1e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM56757.1 - 0.0011 18.3 0.0 0.0025 17.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KUM56757.1 - 0.055 12.7 0.2 0.095 11.9 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KUM56757.1 - 0.09 12.0 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM56757.1 - 0.52 9.8 3.0 0.97 8.9 2.8 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase adh_short PF00106.25 KUM56758.1 - 6.8e-25 87.7 0.0 9.1e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM56758.1 - 1.4e-20 73.9 0.0 1.8e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM56758.1 - 4.2e-05 23.5 0.1 6.6e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM56758.1 - 0.0055 16.2 0.2 0.055 12.9 0.2 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family SoPB_HTH PF18090.1 KUM56758.1 - 0.021 14.9 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 Centromere-binding protein HTH domain NAD_binding_10 PF13460.6 KUM56758.1 - 0.024 14.5 0.7 0.058 13.3 0.5 1.8 2 1 0 2 2 2 0 NAD(P)H-binding DUF1776 PF08643.10 KUM56758.1 - 0.086 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pyr_redox_2 PF07992.14 KUM56759.1 - 8.6e-10 38.3 0.0 4e-09 36.1 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM56759.1 - 0.00063 19.9 0.0 0.0018 18.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KUM56759.1 - 0.023 13.4 0.0 0.038 12.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_7 PF13241.6 KUM56759.1 - 0.04 14.3 0.0 4 7.9 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KUM56759.1 - 0.057 13.4 0.1 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KUM56759.1 - 0.084 11.9 0.0 0.5 9.4 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 KUM56759.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain PMAIP1 PF15150.6 KUM56761.1 - 0.031 14.1 0.5 0.038 13.8 0.5 1.1 1 0 0 1 1 1 0 Phorbol-12-myristate-13-acetate-induced Cerato-platanin PF07249.12 KUM56762.1 - 8.6e-47 158.1 0.6 1e-46 157.9 0.6 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.17 KUM56762.1 - 0.037 13.9 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Barwin family CDH-cyt PF16010.5 KUM56763.1 - 1.1e-24 87.2 0.7 1.6e-24 86.6 0.7 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KUM56763.1 - 1e-06 28.9 12.7 2e-06 28.0 12.7 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 KUM56763.1 - 0.0049 17.1 0.2 0.0098 16.1 0.2 1.5 1 0 0 1 1 1 1 DOMON domain SdpI PF13630.6 KUM56763.1 - 0.023 14.8 6.9 0.023 14.8 6.9 2.8 2 1 0 2 2 2 0 SdpI/YhfL protein family DUF2427 PF10348.9 KUM56763.1 - 0.48 10.2 11.7 0.023 14.4 5.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) DUF3040 PF11239.8 KUM56763.1 - 5.5 7.3 9.9 4.9 7.5 2.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Abhydrolase_3 PF07859.13 KUM56764.1 - 1.4e-40 139.4 0.1 6.5e-33 114.4 0.0 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KUM56764.1 - 3.8e-14 52.3 0.0 6e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KUM56764.1 - 0.021 14.1 0.0 0.066 12.5 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 COesterase PF00135.28 KUM56764.1 - 0.12 11.2 0.1 0.33 9.8 0.1 1.6 1 1 0 1 1 1 0 Carboxylesterase family K_oxygenase PF13434.6 KUM56765.1 - 0.01 15.0 0.0 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KUM56765.1 - 0.028 12.9 0.2 0.43 8.9 0.0 2.3 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KUM56765.1 - 0.039 13.2 0.0 0.67 9.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SLAC1 PF03595.17 KUM56766.1 - 2.5e-70 237.3 46.3 2.8e-70 237.1 46.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Adeno_E3 PF06040.11 KUM56766.1 - 0.047 13.9 1.9 7 6.8 0.0 3.0 3 0 0 3 3 3 0 Adenovirus E3 protein DUF3377 PF11857.8 KUM56766.1 - 0.097 12.6 1.4 1.8 8.6 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Glyco_transf_15 PF01793.16 KUM56767.1 - 2e-127 425.0 10.5 2.5e-127 424.6 10.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase UMP1 PF05348.11 KUM56769.1 - 1.4e-36 125.3 0.0 1.9e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.6 KUM56770.1 - 4.4e-12 46.1 0.0 1e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KUM56770.1 - 0.0026 18.3 0.0 0.0072 16.9 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KUM56770.1 - 0.024 14.4 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Hamartin PF04388.12 KUM56770.1 - 8.3 4.9 12.9 13 4.3 12.9 1.3 1 0 0 1 1 1 0 Hamartin protein GHMP_kinases_N PF00288.26 KUM56771.1 - 2.9e-14 53.1 2.6 6.5e-14 51.9 2.6 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KUM56771.1 - 3.5e-10 40.1 0.0 4.2e-09 36.6 0.0 2.5 2 1 0 2 2 2 1 GHMP kinases C terminal DUF4763 PF15960.5 KUM56771.1 - 0.008 15.5 0.5 0.012 14.9 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) Methyltransf_11 PF08241.12 KUM56772.1 - 2e-21 76.4 0.0 4.4e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM56772.1 - 7.8e-21 74.6 0.0 2.9e-20 72.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM56772.1 - 1e-16 61.1 0.0 1.8e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM56772.1 - 3.2e-15 56.3 0.0 5.3e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM56772.1 - 4.1e-12 46.7 0.0 8.8e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM56772.1 - 5.4e-12 45.5 0.0 6.4e-11 42.0 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KUM56772.1 - 8.1e-11 41.7 0.0 1.1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 KUM56772.1 - 2.5e-06 27.2 0.0 4.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KUM56772.1 - 8.9e-06 25.4 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KUM56772.1 - 0.0027 17.2 0.0 0.0053 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 KUM56772.1 - 0.0033 16.9 0.0 0.005 16.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KUM56772.1 - 0.0037 17.3 0.0 0.0065 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KUM56772.1 - 0.0038 16.2 0.1 0.039 12.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 KUM56772.1 - 0.0052 16.7 0.0 0.053 13.4 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 KUM56772.1 - 0.0068 15.0 0.0 0.0095 14.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 KUM56772.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KUM56772.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain TehB PF03848.14 KUM56772.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.20 KUM56772.1 - 0.04 13.0 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase AlaDh_PNT_C PF01262.21 KUM56772.1 - 0.079 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FtsJ PF01728.19 KUM56772.1 - 0.15 12.2 0.0 0.36 10.9 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase DOT1 PF08123.13 KUM56772.1 - 0.19 11.2 0.0 0.39 10.2 0.0 1.6 1 0 0 1 1 1 0 Histone methylation protein DOT1 Vps54 PF07928.12 KUM56775.1 - 6.8e-51 172.2 0.4 2.8e-50 170.2 0.1 2.3 2 0 0 2 2 2 1 Vps54-like protein DUF2451 PF10474.9 KUM56775.1 - 2e-06 27.8 0.1 4.6e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 KUM56775.1 - 1.3e-05 24.7 0.2 1.3e-05 24.7 0.2 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Rab_bind PF16704.5 KUM56775.1 - 0.13 12.3 0.0 6.3 6.9 0.1 3.1 1 1 1 2 2 2 0 Rab binding domain FMO-like PF00743.19 KUM56776.1 - 6.3e-16 57.9 0.7 3.2e-15 55.6 0.1 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KUM56776.1 - 5.7e-11 42.5 0.0 1.4e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KUM56776.1 - 2e-07 30.5 0.1 2.4e-05 23.6 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KUM56776.1 - 3.6e-07 29.7 0.2 2.9e-06 26.8 0.2 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM56776.1 - 5.8e-07 29.0 0.0 3.4e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM56776.1 - 0.00093 18.9 1.7 0.0081 15.8 1.7 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KUM56776.1 - 0.00098 19.1 0.1 0.12 12.4 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KUM56776.1 - 0.0036 16.6 0.1 0.012 14.9 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Glu_dehyd_C PF16912.5 KUM56776.1 - 0.18 11.3 0.2 9.8 5.6 0.0 2.7 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 KUM56776.1 - 0.23 11.5 0.0 15 5.6 0.0 3.3 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Mqo PF06039.15 KUM56776.1 - 0.25 9.9 0.3 6 5.3 0.0 2.3 2 1 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 KUM56776.1 - 0.4 9.9 1.0 0.81 8.9 0.3 1.7 2 0 0 2 2 2 0 FAD binding domain ATP-grasp_4 PF13535.6 KUM56777.1 - 5.4e-12 45.6 0.0 6e-11 42.2 0.0 2.7 2 1 0 2 2 2 1 ATP-grasp domain ATPgrasp_N PF18130.1 KUM56777.1 - 2e-11 44.3 0.1 4.8e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp N-terminal domain Dala_Dala_lig_C PF07478.13 KUM56777.1 - 3.8e-07 29.9 0.0 6.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 KUM56777.1 - 4.8e-06 26.2 0.0 3.6e-05 23.4 0.0 2.3 3 0 0 3 3 3 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 KUM56777.1 - 0.0013 18.8 0.0 0.034 14.2 0.0 2.6 2 1 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 KUM56777.1 - 0.003 17.2 0.0 0.0063 16.1 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.19 KUM56777.1 - 0.0042 16.9 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MCM PF00493.23 KUM56778.1 - 1.1e-103 345.2 0.1 2.3e-103 344.1 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KUM56778.1 - 7.7e-36 122.7 0.3 1.6e-35 121.7 0.3 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KUM56778.1 - 1.7e-29 102.1 1.9 4.3e-29 100.8 1.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KUM56778.1 - 2.7e-15 56.8 0.1 7e-15 55.5 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KUM56778.1 - 3.8e-06 26.4 0.0 0.00089 18.7 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KUM56778.1 - 5.6e-05 23.2 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KUM56778.1 - 0.00053 19.8 0.0 0.0017 18.2 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KUM56778.1 - 0.063 13.0 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Imm35 PF15567.6 KUM56778.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 35 TTC5_OB PF16669.5 KUM56778.1 - 0.15 11.7 0.0 0.41 10.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain PTR2 PF00854.21 KUM56781.1 - 1.1e-63 215.4 8.5 1.9e-63 214.6 8.5 1.3 1 0 0 1 1 1 1 POT family Rtt106_N PF18215.1 KUM56781.1 - 0.087 12.6 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain DUF267 PF03268.14 KUM56781.1 - 0.31 9.9 3.0 1.2 7.9 0.0 2.7 3 0 0 3 3 3 0 Caenorhabditis protein of unknown function, DUF267 bZIP_1 PF00170.21 KUM56783.1 - 3.3e-05 23.9 8.3 6.7e-05 22.9 8.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KUM56783.1 - 0.021 14.9 8.7 0.021 14.9 8.7 2.0 2 0 0 2 2 2 0 Basic region leucine zipper GvpL_GvpF PF06386.11 KUM56783.1 - 0.24 11.3 2.4 0.4 10.6 2.4 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4407 PF14362.6 KUM56783.1 - 1.2 8.5 3.9 3.1 7.1 3.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HCO3_cotransp PF00955.21 KUM56785.1 - 1.8e-85 287.7 12.4 2.6e-46 158.5 5.7 2.1 1 1 1 2 2 2 2 HCO3- transporter family DEAD PF00270.29 KUM56786.1 - 1.1e-41 142.5 0.0 2.7e-41 141.3 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM56786.1 - 7.3e-31 106.8 0.0 1.6e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM56786.1 - 1e-07 32.1 0.0 3.4e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KUM56786.1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 KUM56786.1 - 0.097 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Stm1_N PF09598.10 KUM56787.1 - 1.9e-16 60.7 5.4 1.9e-16 60.7 5.4 5.5 2 2 1 3 3 3 1 Stm1 Epimerase PF01370.21 KUM56788.1 - 1.4e-13 50.9 1.1 3.3e-10 39.8 0.2 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KUM56788.1 - 3.3e-11 43.4 0.7 5.5e-11 42.7 0.7 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KUM56788.1 - 5.4e-09 36.0 0.6 9.3e-09 35.2 0.6 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KUM56788.1 - 3.9e-06 26.2 0.0 0.042 12.9 0.1 2.0 2 0 0 2 2 2 2 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KUM56788.1 - 1.9e-05 24.2 0.0 0.00012 21.6 0.1 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KUM56788.1 - 2.8e-05 23.3 0.2 7.7e-05 21.8 0.2 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KUM56788.1 - 5.9e-05 23.3 0.5 0.00012 22.3 0.2 1.7 2 0 0 2 2 2 1 TrkA-N domain adh_short PF00106.25 KUM56788.1 - 0.00011 21.8 0.3 0.00017 21.1 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KUM56788.1 - 0.0024 17.1 0.3 0.006 15.8 0.3 1.6 2 0 0 2 2 2 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 KUM56788.1 - 0.0034 17.6 0.2 0.0074 16.6 0.2 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KUM56788.1 - 0.13 12.3 1.0 0.65 10.1 0.9 2.3 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF1793 PF08760.11 KUM56790.1 - 7.1e-70 234.8 0.5 7.1e-70 234.8 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KUM56790.1 - 9.6e-63 210.9 1.2 3e-49 167.0 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KUM56790.1 - 1.3e-49 169.0 1.0 2e-49 168.5 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KUM56790.1 - 0.0065 16.0 0.1 0.018 14.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) adh_short PF00106.25 KUM56791.1 - 2.3e-28 99.0 0.0 2.9e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM56791.1 - 3.4e-21 75.9 0.0 4e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM56791.1 - 4.2e-06 26.8 0.0 6.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM56791.1 - 0.00031 20.3 0.0 0.0098 15.4 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KUM56791.1 - 0.00083 19.0 0.0 0.0021 17.6 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KUM56791.1 - 0.0009 19.2 0.0 0.0017 18.2 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding CPP1-like PF11833.8 KUM56792.1 - 0.27 10.8 1.1 0.57 9.8 0.3 2.0 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Tri3 PF07428.11 KUM56793.1 - 3.7e-06 26.1 0.2 0.0028 16.6 0.0 2.4 2 1 1 3 3 3 2 15-O-acetyltransferase Tri3 PapA_C PF16911.5 KUM56793.1 - 0.0071 16.4 0.0 0.024 14.7 0.0 1.9 1 0 0 1 1 1 1 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus KR PF08659.10 KUM56794.1 - 1.1e-54 185.0 0.0 2.4e-54 184.0 0.0 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KUM56794.1 - 5.4e-53 180.2 0.3 8.9e-53 179.5 0.3 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KUM56794.1 - 5.5e-52 177.2 0.0 1.1e-51 176.3 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KUM56794.1 - 1.9e-28 98.9 0.1 4.6e-28 97.6 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KUM56794.1 - 2.2e-19 70.0 0.0 1e-18 67.8 0.0 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KUM56794.1 - 6e-15 55.4 0.3 7.5e-14 51.8 0.0 3.0 4 0 0 4 4 4 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM56794.1 - 3.3e-09 37.9 0.0 1.3e-08 36.0 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KUM56794.1 - 1.4e-08 34.4 0.0 1.1e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 KUM56794.1 - 5.1e-06 26.8 0.4 1.8e-05 25.0 0.4 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KUM56794.1 - 1.7e-05 24.6 0.1 3.9e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 KUM56794.1 - 7e-05 22.5 0.0 0.00018 21.1 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.26 KUM56795.1 - 3.1e-70 236.6 0.0 3.5e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 KUM56795.1 - 0.0076 15.6 0.2 0.024 14.0 0.1 1.7 1 1 1 2 2 2 1 Thiolase, N-terminal domain DNA_gyraseB_C PF00986.21 KUM56795.1 - 0.076 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus ACP_syn_III PF08545.10 KUM56795.1 - 0.19 11.6 1.2 0.33 10.8 0.7 1.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short PF00106.25 KUM56797.1 - 6.7e-40 136.6 3.1 8.6e-40 136.3 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM56797.1 - 1.9e-35 122.5 3.0 2.9e-35 121.9 3.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM56797.1 - 6.5e-11 42.5 3.2 1.5e-09 38.0 3.2 2.1 1 1 0 1 1 1 1 KR domain DUF1944 PF09175.10 KUM56797.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1944) DAO PF01266.24 KUM56797.1 - 0.17 11.4 6.1 1.2 8.7 4.5 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase ThiF PF00899.21 KUM56797.1 - 1.3 8.3 5.3 7.8 5.8 5.2 2.0 1 1 0 1 1 1 0 ThiF family Zn_clus PF00172.18 KUM56799.1 - 0.004 17.3 4.7 0.01 16.0 4.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TF_Zn_Ribbon PF08271.12 KUM56799.1 - 0.03 13.8 0.8 0.3 10.6 0.0 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-BED PF02892.15 KUM56799.1 - 0.037 14.0 0.3 0.092 12.8 0.3 1.7 1 0 0 1 1 1 0 BED zinc finger CPL PF08144.11 KUM56800.1 - 2.4e-27 96.0 0.0 2.4e-27 96.0 0.0 3.8 4 0 0 4 4 4 1 CPL (NUC119) domain Bt_P21 PF05560.11 KUM56800.1 - 0.0055 16.3 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 Bacillus thuringiensis P21 molecular chaperone protein PBECR2 PF18810.1 KUM56800.1 - 0.17 12.2 1.1 2.1 8.7 0.0 3.0 3 0 0 3 3 3 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Hid1 PF12722.7 KUM56800.1 - 0.19 9.8 10.0 0.33 9.0 10.0 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ATP-synt_10 PF05176.14 KUM56802.1 - 9.8e-83 277.3 0.0 1.3e-82 276.9 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DNA_pol_B_palm PF14792.6 KUM56803.1 - 6.3e-35 119.8 0.0 1.2e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KUM56803.1 - 2.2e-24 85.4 0.0 5.9e-24 84.0 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KUM56803.1 - 1.3e-19 70.3 0.6 2.6e-19 69.4 0.6 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KUM56803.1 - 1.1e-15 57.2 0.0 3.7e-15 55.5 0.0 2.0 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda BRCT PF00533.26 KUM56803.1 - 0.00094 19.5 0.0 0.0066 16.8 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.23 KUM56803.1 - 0.017 15.4 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain V-SNARE_C PF12352.8 KUM56804.1 - 2.6e-12 46.8 0.8 1.4e-11 44.5 0.0 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.6 KUM56804.1 - 0.0015 17.3 3.4 0.0021 16.8 3.4 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Sec20 PF03908.13 KUM56804.1 - 0.061 13.2 0.7 1.5 8.7 0.0 2.9 3 1 0 3 3 3 0 Sec20 DUF2890 PF11081.8 KUM56804.1 - 0.098 12.8 0.5 0.24 11.5 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) Syntaxin-6_N PF09177.11 KUM56804.1 - 0.13 12.8 4.6 0.088 13.4 2.5 1.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal CENP-H PF05837.12 KUM56804.1 - 1.5 9.2 8.1 0.83 10.1 5.8 1.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ANAPC4_WD40 PF12894.7 KUM56805.1 - 0.0092 16.3 0.1 0.022 15.0 0.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Med16 PF11635.8 KUM56805.1 - 0.09 10.7 0.0 0.2 9.6 0.0 1.5 2 0 0 2 2 2 0 Mediator complex subunit 16 Med16 PF11635.8 KUM56806.1 - 4.2e-46 157.3 0.0 5.1e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 ANAPC4_WD40 PF12894.7 KUM56806.1 - 0.076 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L29 PF00831.23 KUM56807.1 - 8.4e-18 64.1 0.9 8.4e-18 64.1 0.9 2.1 2 1 1 3 3 3 1 Ribosomal L29 protein CorA PF01544.18 KUM56807.1 - 0.076 12.3 3.2 0.095 12.0 3.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Med16 PF11635.8 KUM56808.1 - 0.00071 17.6 0.0 0.00071 17.6 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Med16 PF11635.8 KUM56809.1 - 7e-88 295.4 0.0 7.9e-88 295.2 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 DUF3336 PF11815.8 KUM56810.1 - 4.3e-48 162.5 3.0 6.7e-48 161.9 3.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KUM56810.1 - 1.1e-16 61.7 0.7 8.3e-16 58.8 0.1 2.7 3 1 0 3 3 3 1 Patatin-like phospholipase Dynamin_N PF00350.23 KUM56810.1 - 0.19 11.8 0.1 0.46 10.5 0.1 1.6 1 1 0 1 1 1 0 Dynamin family SAM_2 PF07647.17 KUM56814.1 - 1.8e-08 34.4 0.1 3.8e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KUM56814.1 - 0.00059 20.2 0.1 0.0014 19.0 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 KUM56814.1 - 0.091 13.0 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Rab5ip PF07019.12 KUM56816.1 - 1.2e-19 70.6 9.5 1.9e-19 70.0 9.5 1.3 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) TPR_19 PF14559.6 KUM56817.1 - 7.5e-19 68.0 16.7 1e-06 29.1 0.0 7.5 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KUM56817.1 - 2e-13 50.0 17.2 0.00015 22.3 0.6 9.8 6 3 4 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 KUM56817.1 - 8.6e-13 48.7 11.6 4.5e-05 24.0 3.6 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KUM56817.1 - 1.6e-12 46.8 3.2 0.12 12.8 0.1 7.0 8 0 0 8 8 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM56817.1 - 1.9e-12 47.2 17.0 0.0033 17.6 0.0 7.2 7 1 1 8 8 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KUM56817.1 - 6.5e-11 41.5 26.4 0.34 11.1 0.1 10.1 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 KUM56817.1 - 1.9e-09 37.1 2.9 0.02 14.6 0.1 5.8 5 1 1 6 6 6 2 TPR repeat TPR_7 PF13176.6 KUM56817.1 - 9.9e-09 34.6 19.1 0.23 11.6 0.0 8.3 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KUM56817.1 - 1.1e-08 34.6 19.8 0.31 11.4 0.1 8.7 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KUM56817.1 - 2.2e-08 33.6 18.0 0.4 10.6 0.0 9.8 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_12 PF13424.6 KUM56817.1 - 1.8e-06 28.1 22.2 0.12 12.6 0.1 7.4 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 KUM56817.1 - 0.0002 20.7 2.5 2.6 7.2 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KUM56817.1 - 0.00045 20.3 10.8 0.0014 18.8 0.2 5.7 4 1 3 7 7 7 2 Tetratricopeptide repeat SNAP PF14938.6 KUM56817.1 - 0.0037 16.7 0.5 0.42 10.0 0.0 2.6 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_20 PF14561.6 KUM56817.1 - 0.0065 16.8 3.4 2.4 8.5 0.1 4.8 5 1 0 5 5 4 1 Tetratricopeptide repeat NARP1 PF12569.8 KUM56817.1 - 0.032 13.2 3.5 14 4.5 0.2 4.0 3 2 2 5 5 5 0 NMDA receptor-regulated protein 1 BTAD PF03704.17 KUM56817.1 - 0.061 13.8 2.3 1 9.8 0.4 3.4 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 KUM56817.1 - 0.07 13.8 16.0 2.2 9.1 0.0 7.2 9 0 0 9 9 6 0 Tetratricopeptide repeat ChAPs PF09295.10 KUM56817.1 - 0.097 11.7 0.0 0.42 9.5 0.0 2.0 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Alkyl_sulf_dimr PF14863.6 KUM56817.1 - 0.18 12.2 0.6 14 6.1 0.0 3.0 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation PPR PF01535.20 KUM56817.1 - 2.2 8.7 6.0 4.1 7.9 0.3 3.9 5 0 0 5 5 3 0 PPR repeat TPR_10 PF13374.6 KUM56817.1 - 2.8 7.9 9.9 1.1 9.3 0.4 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat YL1 PF05764.13 KUM56817.1 - 5.3 7.1 6.7 0.65 10.1 2.0 1.8 2 0 0 2 2 1 0 YL1 nuclear protein TPR_MalT PF17874.1 KUM56817.1 - 5.3 6.3 10.8 9.6 5.5 0.1 4.4 4 2 0 5 5 5 0 MalT-like TPR region TPR_4 PF07721.14 KUM56817.1 - 8.4 7.3 14.6 24 6.0 0.2 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat MFS_1 PF07690.16 KUM56818.1 - 5.7e-29 101.1 42.2 1.3e-25 90.1 32.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KUM56818.1 - 0.032 13.5 18.7 0.055 12.8 18.7 1.3 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB PNP_UDP_1 PF01048.20 KUM56819.1 - 4.3e-14 52.3 0.0 6.7e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Adap_comp_sub PF00928.21 KUM56820.1 - 2.6e-91 305.7 0.0 4.8e-91 304.8 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KUM56820.1 - 1e-08 35.2 0.2 1.6e-08 34.6 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KUM56820.1 - 0.11 11.9 0.0 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Hydrophobin PF01185.18 KUM56822.1 - 6e-09 36.4 6.4 8.3e-09 36.0 6.4 1.2 1 0 0 1 1 1 1 Fungal hydrophobin CFEM PF05730.11 KUM56823.1 - 5.3e-05 23.2 5.2 5.3e-05 23.2 5.2 2.3 2 0 0 2 2 2 1 CFEM domain Tme5_EGF_like PF09064.10 KUM56823.1 - 0.97 9.4 9.0 0.052 13.4 2.5 2.3 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like WW PF00397.26 KUM56824.1 - 7.4e-11 42.0 2.7 1.8e-10 40.7 2.7 1.7 1 0 0 1 1 1 1 WW domain WRW PF10206.9 KUM56824.1 - 0.11 12.8 1.3 0.79 10.1 0.6 2.3 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f Acyl-CoA_dh_M PF02770.19 KUM56825.1 - 0.0039 17.4 0.0 0.012 15.8 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain NMO PF03060.15 KUM56826.1 - 5.9e-55 186.9 1.1 1.6e-53 182.3 1.1 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KUM56826.1 - 6.5e-14 51.7 0.0 7.3e-13 48.2 0.0 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KUM56826.1 - 1e-05 24.7 0.5 1.9e-05 23.9 0.5 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KUM56826.1 - 0.012 15.0 0.3 0.084 12.3 0.2 2.1 1 1 0 1 1 1 0 Histidine biosynthesis protein NanE PF04131.14 KUM56826.1 - 0.019 14.2 0.1 0.035 13.3 0.1 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 KUM56826.1 - 0.05 12.7 0.4 0.12 11.5 0.4 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase Sdh_cyt PF01127.22 KUM56827.1 - 1.2e-24 86.7 5.7 1.5e-24 86.3 5.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ribonucleas_3_3 PF14622.6 KUM56828.1 - 8e-28 97.2 0.0 1.4e-27 96.4 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KUM56828.1 - 2.7e-06 27.9 0.0 7.8e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Glyco_hydro_72 PF03198.14 KUM56829.1 - 4e-131 437.0 5.6 5e-131 436.6 5.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KUM56829.1 - 1.4e-19 70.5 1.3 3.6e-19 69.2 1.3 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 KUM56829.1 - 0.00058 19.4 0.4 0.0019 17.7 0.4 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KUM56829.1 - 0.00065 18.9 2.9 0.0017 17.5 2.9 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Neur PF00064.18 KUM56830.1 - 0.17 10.6 0.1 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 Neuraminidase Mannitol_dh_C PF08125.13 KUM56831.1 - 1.7e-72 243.9 0.0 2.6e-72 243.3 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KUM56831.1 - 4e-43 147.2 0.0 7.9e-43 146.2 0.0 1.5 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain GMC_oxred_C PF05199.13 KUM56833.1 - 3.9e-32 111.7 0.0 8.5e-32 110.7 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KUM56833.1 - 5.1e-21 75.3 0.0 4e-12 46.1 0.6 2.1 1 1 1 2 2 2 2 GMC oxidoreductase PsiA PF06952.11 KUM56833.1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 PsiA protein Na_Ca_ex PF01699.24 KUM56835.1 - 3.8e-19 69.1 15.5 7.3e-18 65.0 9.0 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Fungal_trans PF04082.18 KUM56836.1 - 4e-19 68.7 0.0 6.7e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM56836.1 - 5.5e-05 23.2 7.6 9.9e-05 22.4 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.29 KUM56838.1 - 2.5e-97 322.4 0.0 3.6e-47 160.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KUM56838.1 - 2.5e-22 78.4 5.9 2.1e-12 46.6 1.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KUM56838.1 - 5.5e-19 68.1 1.0 1.6e-18 66.7 0.5 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KUM56838.1 - 1.2e-14 54.3 0.0 6.5e-06 26.0 0.0 3.7 4 1 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KUM56838.1 - 2.2e-14 53.9 0.0 1e-07 32.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KUM56838.1 - 1.1e-12 48.3 0.0 1.7e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KUM56838.1 - 1.5e-12 48.2 0.0 0.00021 21.7 0.0 4.8 3 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 KUM56838.1 - 2.1e-11 43.9 0.6 2e-05 24.6 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 KUM56838.1 - 1.9e-09 37.1 0.0 4.1e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 KUM56838.1 - 2.9e-09 37.3 0.4 0.032 14.5 0.0 4.3 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 KUM56838.1 - 3.2e-09 36.5 0.1 0.0016 17.7 0.0 2.7 2 1 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 KUM56838.1 - 1.4e-07 31.1 0.6 0.011 15.2 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 KUM56838.1 - 5.2e-07 29.6 0.1 1.6e-05 24.8 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 KUM56838.1 - 5.4e-07 29.5 0.0 0.019 14.7 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 KUM56838.1 - 5.8e-07 29.9 0.0 0.029 14.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 KUM56838.1 - 6.9e-07 29.4 0.0 0.016 15.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KUM56838.1 - 7.4e-07 29.8 0.0 0.029 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KUM56838.1 - 1.1e-06 28.4 3.5 0.35 10.4 0.1 4.6 3 2 1 5 5 5 2 AAA domain ATPase PF06745.13 KUM56838.1 - 1.9e-06 27.4 0.4 0.51 9.6 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 KUM56838.1 - 3.7e-06 26.6 0.0 0.042 13.3 0.0 3.4 3 2 0 3 3 3 2 P-loop containing dynein motor region AAA_24 PF13479.6 KUM56838.1 - 9.3e-06 25.5 0.0 0.13 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 KUM56838.1 - 1.5e-05 24.2 0.1 0.052 12.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 KUM56838.1 - 1.9e-05 23.9 0.0 0.015 14.5 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 KUM56838.1 - 2.3e-05 24.7 0.0 0.18 12.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 KUM56838.1 - 3.6e-05 23.5 0.1 0.43 10.3 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.18 KUM56838.1 - 4.5e-05 23.4 0.0 0.27 11.1 0.0 3.2 4 0 0 4 4 3 2 Bacterial dnaA protein ABC_tran PF00005.27 KUM56838.1 - 0.00013 22.4 0.0 0.56 10.7 0.0 3.6 3 1 0 3 3 2 1 ABC transporter TsaE PF02367.17 KUM56838.1 - 0.00015 21.8 0.0 0.33 10.9 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KUM56838.1 - 0.00018 22.0 0.4 0.6 10.5 0.0 3.4 4 0 0 4 4 2 1 AAA domain ResIII PF04851.15 KUM56838.1 - 0.00024 21.2 0.0 0.078 13.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KUM56838.1 - 0.00026 20.5 0.4 0.7 9.3 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.12 KUM56838.1 - 0.00032 20.7 0.1 0.18 11.7 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_11 PF13086.6 KUM56838.1 - 0.00032 20.6 0.2 1 9.1 0.1 2.7 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.11 KUM56838.1 - 0.00038 20.3 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KUM56838.1 - 0.00049 19.9 0.2 0.56 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KUM56838.1 - 0.00061 19.8 0.0 2.3 8.1 0.0 3.6 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KUM56838.1 - 0.0017 17.6 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KUM56838.1 - 0.0042 16.9 0.0 0.35 10.6 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KUM56838.1 - 0.0054 17.1 0.8 5.7 7.3 0.0 3.4 3 1 0 4 4 2 0 AAA domain NTPase_1 PF03266.15 KUM56838.1 - 0.0071 16.3 0.7 2.5 8.0 0.0 4.1 4 0 0 4 4 3 1 NTPase NB-ARC PF00931.22 KUM56838.1 - 0.0087 15.3 0.2 1.7 7.7 0.0 2.7 3 0 0 3 3 2 1 NB-ARC domain Zeta_toxin PF06414.12 KUM56838.1 - 0.0099 15.2 0.0 6.1 6.1 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin KAP_NTPase PF07693.14 KUM56838.1 - 0.011 15.0 0.2 0.93 8.7 0.0 3.0 2 2 0 3 3 3 0 KAP family P-loop domain IPT PF01745.16 KUM56838.1 - 0.017 14.5 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Sigma54_activ_2 PF14532.6 KUM56838.1 - 0.026 14.6 0.0 3.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Zot PF05707.12 KUM56838.1 - 0.037 13.7 0.0 2 8.0 0.0 3.1 3 1 0 3 3 2 0 Zonular occludens toxin (Zot) UFD1 PF03152.14 KUM56838.1 - 0.047 13.2 0.0 0.37 10.2 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Cytidylate_kin PF02224.18 KUM56838.1 - 0.049 13.4 0.0 10 5.8 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase AFG1_ATPase PF03969.16 KUM56838.1 - 0.063 12.2 0.0 8.7 5.1 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_6 PF12774.7 KUM56838.1 - 0.068 12.1 0.2 9.1 5.1 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region MFS_1 PF07690.16 KUM56839.1 - 2.6e-40 138.4 39.5 2.6e-40 138.4 39.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3464 PF11947.8 KUM56839.1 - 0.11 12.2 5.2 3.2 7.5 0.3 3.7 4 0 0 4 4 4 0 Photosynthesis affected mutant 68 HEAT_2 PF13646.6 KUM56840.1 - 1e-06 29.0 3.9 0.0064 16.9 0.0 4.2 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 KUM56840.1 - 7.4e-05 22.8 1.0 0.86 9.6 0.0 4.4 4 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KUM56840.1 - 0.00015 21.7 8.1 0.076 13.3 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KUM56840.1 - 0.015 15.8 2.7 1.4 9.5 0.0 4.5 4 0 0 4 4 4 0 HEAT-like repeat Nipped-B_C PF12830.7 KUM56840.1 - 0.022 14.7 0.3 0.48 10.3 0.1 2.7 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus Adaptin_N PF01602.20 KUM56840.1 - 0.092 11.3 2.0 1 7.8 0.0 3.2 4 1 0 4 4 4 0 Adaptin N terminal region XPC-binding PF09280.11 KUM56840.1 - 0.42 10.4 3.2 3.9 7.3 0.6 2.6 2 0 0 2 2 2 0 XPC-binding domain RIX1 PF08167.12 KUM56840.1 - 0.47 10.2 4.1 3.3 7.4 0.0 3.8 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis SNF5 PF04855.12 KUM56841.1 - 2.4e-63 214.1 0.5 2.3e-62 210.9 0.5 2.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Exo_endo_phos PF03372.23 KUM56842.1 - 2.9e-10 40.1 0.1 9.3e-10 38.4 0.1 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M24 PF00557.24 KUM56844.1 - 6.6e-08 32.5 0.1 9.7e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 STAR_dimer PF16544.5 KUM56844.1 - 0.062 12.9 0.6 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 Homodimerisation region of STAR domain protein DAO PF01266.24 KUM56845.1 - 2.7e-32 112.7 0.1 3.3e-32 112.5 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KUM56845.1 - 0.00088 18.6 0.7 0.0012 18.1 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 KUM56845.1 - 0.0014 18.6 0.8 0.0034 17.3 0.3 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KUM56845.1 - 0.0014 17.8 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KUM56845.1 - 0.002 18.3 0.1 0.0052 17.0 0.0 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KUM56845.1 - 0.012 16.0 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 KUM56845.1 - 0.017 15.7 0.5 0.038 14.5 0.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KUM56845.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KUM56845.1 - 0.018 14.3 0.1 0.03 13.6 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KUM56845.1 - 0.026 14.2 0.8 0.026 14.2 0.8 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KUM56845.1 - 0.033 13.5 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KUM56845.1 - 0.037 14.6 0.0 0.07 13.7 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KUM56845.1 - 0.054 12.8 0.0 0.25 10.6 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KUM56845.1 - 0.1 12.2 2.0 0.16 11.5 1.2 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.12 KUM56845.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 KUM56845.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 KUM56845.1 - 0.16 11.5 0.1 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus LRR_4 PF12799.7 KUM56846.1 - 0.00021 21.6 6.2 0.83 10.2 0.0 5.1 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) MliC PF09864.9 KUM56846.1 - 0.2 11.6 0.1 0.43 10.6 0.1 1.4 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme LRR_1 PF00560.33 KUM56846.1 - 0.25 12.0 2.6 2.5e+02 2.9 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 KUM56846.1 - 0.29 11.3 8.5 1.1 9.5 0.2 4.4 5 0 0 5 5 5 0 Leucine Rich repeat DUF4293 PF14126.6 KUM56847.1 - 0.14 12.4 5.1 0.24 11.7 5.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Retrotrans_gag PF03732.17 KUM56848.1 - 0.00036 20.7 0.4 0.00092 19.4 0.2 1.8 1 1 0 1 1 1 1 Retrotransposon gag protein TF_AP-2 PF03299.14 KUM56848.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Transcription factor AP-2 SET PF00856.28 KUM56849.1 - 2.1e-12 47.7 0.6 1.2e-10 42.0 0.3 3.1 3 1 0 3 3 3 1 SET domain Hydrolase_6 PF13344.6 KUM56850.1 - 1.4e-21 76.5 0.0 2.3e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KUM56850.1 - 8e-20 70.7 0.0 1.9e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KUM56850.1 - 0.0021 18.4 0.0 0.47 10.7 0.0 2.8 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Apt1 PF10351.9 KUM56850.1 - 0.011 14.6 0.2 0.03 13.2 0.0 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain PGP_phosphatase PF09419.10 KUM56850.1 - 0.016 14.8 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase HAD_2 PF13419.6 KUM56850.1 - 0.13 12.3 0.0 0.84 9.7 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Glyco_hydro_12 PF01670.16 KUM56851.1 - 2.5e-73 246.6 8.7 3.1e-73 246.3 8.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Fungal_trans PF04082.18 KUM56852.1 - 3.6e-24 85.2 0.0 7.3e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_3 PF00202.21 KUM56853.1 - 1.2e-91 307.4 0.0 1.5e-91 307.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III HAD_2 PF13419.6 KUM56855.1 - 5.3e-11 42.9 0.0 9.1e-11 42.2 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KUM56855.1 - 0.039 14.2 0.0 0.46 10.7 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aldedh PF00171.22 KUM56856.1 - 1e-166 555.1 0.1 1.1e-166 554.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1726 PF08351.11 KUM56856.1 - 0.041 13.8 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) DUF1487 PF07368.11 KUM56856.1 - 0.11 12.0 0.0 0.52 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) LRR_4 PF12799.7 KUM56858.1 - 0.089 13.2 0.4 3.1 8.4 0.1 2.9 2 2 0 2 2 2 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KUM56858.1 - 0.21 11.5 1.8 0.24 11.3 0.6 1.7 2 0 0 2 2 2 0 F-box-like Glyco_hydro_16 PF00722.21 KUM56860.1 - 5e-45 153.1 4.3 6.5e-45 152.8 4.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MSC PF09402.10 KUM56861.1 - 1.3e-106 356.9 0.0 1.7e-106 356.5 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KUM56861.1 - 1.5e-16 59.8 0.0 2.8e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain PP2C PF00481.21 KUM56863.1 - 5.6e-52 176.9 0.0 8.6e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 KUM56863.1 - 1.7e-33 114.1 62.7 0.00015 22.1 0.8 12.7 8 2 2 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KUM56863.1 - 2.6e-33 113.6 62.4 2.7e-06 27.0 0.7 11.1 6 4 5 12 12 12 10 Leucine rich repeat Guanylate_cyc PF00211.20 KUM56863.1 - 8.2e-26 90.8 0.0 1.7e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 KUM56863.1 - 8.1e-07 28.7 12.9 0.018 14.6 0.1 4.3 2 1 2 4 4 4 3 Leucine-rich repeat LRR_5 PF13306.6 KUM56863.1 - 5.9e-06 26.3 9.1 0.3 11.0 1.8 4.7 3 2 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) Ad_cyc_g-alpha PF08509.11 KUM56863.1 - 0.00096 18.8 0.2 0.0037 17.0 0.2 2.0 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_1 PF00560.33 KUM56863.1 - 0.001 19.3 59.8 6.8 7.7 0.1 15.5 16 1 0 16 16 16 3 Leucine Rich Repeat ABC_tran PF00005.27 KUM56865.1 - 5e-45 153.4 0.0 4.6e-24 85.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KUM56865.1 - 5.1e-38 131.3 26.8 6.7e-28 98.1 11.2 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KUM56865.1 - 6.1e-17 61.8 0.4 0.0016 17.9 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KUM56865.1 - 1.5e-11 44.7 4.9 0.0072 16.2 0.1 4.3 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KUM56865.1 - 1.7e-08 34.1 0.6 0.003 17.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KUM56865.1 - 4.8e-07 29.8 0.1 0.022 14.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KUM56865.1 - 7e-07 30.0 0.1 0.018 15.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KUM56865.1 - 1.6e-06 28.4 0.3 0.16 12.2 0.3 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KUM56865.1 - 1.7e-06 28.5 0.4 0.033 14.6 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 KUM56865.1 - 3.8e-06 26.2 0.1 0.08 12.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_7 PF12775.7 KUM56865.1 - 4e-05 23.2 0.1 0.21 11.1 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KUM56865.1 - 0.00015 21.8 0.3 1 9.5 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF815 PF05673.13 KUM56865.1 - 0.0002 20.6 0.2 0.087 12.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) ATPase_2 PF01637.18 KUM56865.1 - 0.00045 20.2 0.0 1 9.2 0.0 2.7 3 0 0 3 3 2 2 ATPase domain predominantly from Archaea cobW PF02492.19 KUM56865.1 - 0.00061 19.4 1.2 0.19 11.3 0.1 2.6 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 KUM56865.1 - 0.002 17.5 0.2 0.34 10.2 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family Sigma54_activat PF00158.26 KUM56865.1 - 0.002 17.8 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Adeno_IVa2 PF02456.15 KUM56865.1 - 0.0025 16.7 0.1 1.3 7.7 0.0 2.2 2 0 0 2 2 2 2 Adenovirus IVa2 protein SbcCD_C PF13558.6 KUM56865.1 - 0.0028 17.9 0.3 1.1 9.5 0.0 2.8 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.7 KUM56865.1 - 0.0056 15.7 0.0 3.4 6.5 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_15 PF13175.6 KUM56865.1 - 0.0075 16.0 0.1 2.3 7.8 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 KUM56865.1 - 0.0085 16.2 1.0 0.37 10.8 0.1 2.5 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.12 KUM56865.1 - 0.0095 15.2 0.1 2.2 7.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin TrwB_AAD_bind PF10412.9 KUM56865.1 - 0.021 13.7 0.6 4.9 6.0 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 KUM56865.1 - 0.028 14.4 0.9 6.5 6.7 0.1 2.6 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 KUM56865.1 - 0.031 14.2 0.1 0.73 9.7 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 KUM56865.1 - 0.038 13.7 0.0 0.68 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KUM56865.1 - 0.039 14.0 0.6 3.6 7.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KUM56865.1 - 0.041 13.6 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KUM56865.1 - 0.066 13.6 0.0 1.8 9.0 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KUM56865.1 - 0.073 12.8 0.0 3.8 7.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KUM56865.1 - 0.1 12.2 0.0 13 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KUM56865.1 - 0.11 12.6 0.4 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain TsaE PF02367.17 KUM56865.1 - 0.17 11.9 0.2 24 4.9 0.0 2.9 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA12 PF10443.9 KUM56865.1 - 0.2 10.4 0.1 4.5 5.9 0.0 2.1 2 0 0 2 2 2 0 RNA12 protein PetM PF08041.11 KUM56865.1 - 0.35 10.5 2.9 1.8 8.2 2.9 2.3 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 Tannase PF07519.11 KUM56866.1 - 6.9e-85 285.7 0.4 1.2e-43 149.7 0.1 2.0 1 1 1 2 2 2 2 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KUM56866.1 - 1e-05 25.1 0.1 0.14 11.6 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family CAT PF00302.18 KUM56866.1 - 0.063 13.2 0.1 0.095 12.6 0.1 1.3 1 0 0 1 1 1 0 Chloramphenicol acetyltransferase DUF3176 PF11374.8 KUM56867.1 - 9.5e-31 106.2 1.7 2.2e-30 105.0 0.5 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3176) NAD_binding_10 PF13460.6 KUM56868.1 - 2.6e-33 115.4 0.0 3e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KUM56868.1 - 4.7e-09 36.2 0.0 7.6e-09 35.5 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KUM56868.1 - 9.3e-07 28.5 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PAC2 PF09754.9 KUM56868.1 - 0.012 15.6 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 PAC2 family TrkA_N PF02254.18 KUM56868.1 - 0.018 15.3 0.0 0.042 14.1 0.0 1.7 1 1 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.19 KUM56868.1 - 0.098 11.6 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KUM56868.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NIF PF03031.18 KUM56869.1 - 6.2e-27 94.3 0.1 3.5e-25 88.6 0.1 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase RRP36 PF06102.12 KUM56870.1 - 7e-46 156.2 26.3 7e-46 156.2 26.3 2.2 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 ALMT PF11744.8 KUM56870.1 - 0.076 11.8 21.5 0.021 13.7 10.3 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter EF1G PF00647.19 KUM56872.1 - 2.4e-41 140.1 0.9 4.4e-41 139.3 0.2 1.8 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KUM56872.1 - 2.3e-14 53.3 0.0 4.9e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KUM56872.1 - 1.1e-11 44.8 0.0 8.7e-11 42.0 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KUM56872.1 - 3.3e-10 39.9 0.3 1.8e-09 37.5 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KUM56872.1 - 0.00027 21.1 0.0 0.00072 19.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KUM56872.1 - 0.0004 20.7 0.0 0.00081 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KUM56872.1 - 0.012 15.8 0.0 0.037 14.3 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KUM56872.1 - 0.043 13.6 0.0 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KUM56872.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein OAD_gamma PF04277.13 KUM56872.1 - 2.2 8.9 6.0 0.37 11.4 2.2 1.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Ribosomal_S9 PF00380.19 KUM56874.1 - 1.9e-38 131.7 1.2 2.5e-38 131.3 0.5 1.6 2 0 0 2 2 2 1 Ribosomal protein S9/S16 PDEase_I_N PF08499.12 KUM56874.1 - 0.015 15.1 0.9 0.075 12.9 0.0 2.2 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Aminotran_5 PF00266.19 KUM56876.1 - 4.3e-49 167.4 0.0 4.5e-48 164.1 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KUM56876.1 - 4.3e-05 22.9 0.0 6.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KUM56876.1 - 0.00041 19.0 0.0 0.00068 18.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Big_10 PF17964.1 KUM56876.1 - 0.018 15.0 0.1 0.031 14.3 0.1 1.3 1 0 0 1 1 1 0 Bacterial Ig domain Robl_LC7 PF03259.17 KUM56877.1 - 1.1e-06 28.3 0.1 0.011 15.5 0.0 3.2 3 0 0 3 3 3 2 Roadblock/LC7 domain DUF4988 PF16378.5 KUM56877.1 - 0.068 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function bZIP_2 PF07716.15 KUM56878.1 - 0.15 12.1 0.5 0.51 10.5 0.5 1.8 1 0 0 1 1 1 0 Basic region leucine zipper Peptidase_S30 PF01577.16 KUM56878.1 - 1.2 8.7 4.2 3.1 7.3 0.4 2.2 2 0 0 2 2 2 0 Potyvirus P1 protease DUF1298 PF06974.13 KUM56879.1 - 0.1 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) YidC_periplas PF14849.6 KUM56879.1 - 0.15 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 YidC periplasmic domain Ipi1_N PF12333.8 KUM56881.1 - 4.5e-28 97.8 0.6 2.4e-27 95.5 0.0 2.3 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.6 KUM56881.1 - 0.15 12.6 1.0 7.5 7.2 0.2 2.5 1 1 1 2 2 2 0 HEAT-like repeat GATA PF00320.27 KUM56883.1 - 1.7e-16 59.5 2.3 3.1e-16 58.7 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KUM56883.1 - 7.5e-13 48.1 2.4 1.6e-12 47.0 2.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AreA_N PF07573.11 KUM56883.1 - 4.3e-11 43.3 3.5 4.3e-11 43.3 3.5 3.8 4 0 0 4 4 4 1 Nitrogen regulatory protein AreA N terminus FAD_binding_3 PF01494.19 KUM56884.1 - 1.2e-09 37.9 1.5 1.1e-08 34.8 1.5 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KUM56884.1 - 0.001 19.2 0.0 0.0025 18.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM56884.1 - 0.0013 18.4 3.2 0.033 13.8 0.2 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KUM56884.1 - 0.0045 17.0 0.1 0.012 15.6 0.1 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KUM56884.1 - 0.045 13.0 0.0 0.22 10.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KUM56884.1 - 0.063 12.1 0.1 0.23 10.2 0.1 1.7 2 0 0 2 2 2 0 MCRA family Lycopene_cycl PF05834.12 KUM56884.1 - 0.1 11.7 0.5 1.2 8.1 0.5 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KUM56884.1 - 0.11 11.4 0.1 0.28 10.0 0.0 1.7 1 1 1 2 2 2 0 Tryptophan halogenase Calcipressin PF04847.12 KUM56885.1 - 1.7e-30 106.1 0.3 2.2e-30 105.8 0.3 1.1 1 0 0 1 1 1 1 Calcipressin DUF2457 PF10446.9 KUM56886.1 - 0.2 10.8 3.1 0.23 10.6 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ATE_C PF04377.15 KUM56887.1 - 1.7e-48 164.7 1.4 2.4e-48 164.2 1.4 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus Acetyltransf_6 PF13480.7 KUM56887.1 - 0.00031 20.9 0.1 0.00053 20.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Neil1-DNA_bind PF09292.10 KUM56887.1 - 0.15 12.1 3.2 2.6 8.1 0.8 2.4 2 0 0 2 2 2 0 Endonuclease VIII-like 1, DNA bind RNA_pol_A_bac PF01000.26 KUM56888.1 - 1.2e-30 106.1 0.0 1.9e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KUM56888.1 - 5.9e-14 51.2 0.0 8.2e-14 50.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NUDIX PF00293.28 KUM56889.1 - 1.4e-17 64.0 0.5 1.7e-17 63.7 0.5 1.1 1 0 0 1 1 1 1 NUDIX domain GrpE PF01025.19 KUM56891.1 - 1.1e-38 132.5 6.0 1.7e-38 131.9 6.0 1.3 1 0 0 1 1 1 1 GrpE Phage_Gp23 PF10669.9 KUM56891.1 - 0.067 13.5 3.3 0.13 12.6 3.3 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) HisK_N PF09385.10 KUM56891.1 - 0.09 12.7 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 Histidine kinase N terminal MFS_1 PF07690.16 KUM56892.1 - 2.1e-22 79.6 32.2 2.1e-22 79.6 32.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KUM56892.1 - 1.8e-07 30.8 15.4 0.00032 20.1 3.6 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF4381 PF14316.6 KUM56892.1 - 0.042 14.1 0.0 0.56 10.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF2140 PF09911.9 KUM56892.1 - 0.058 12.9 0.1 9.5 5.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) Trp_oprn_chp PF09534.10 KUM56892.1 - 0.064 13.0 0.0 1.4 8.7 0.0 2.5 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) AA_permease_2 PF13520.6 KUM56893.1 - 1.5e-76 258.0 32.6 1.8e-76 257.7 32.6 1.1 1 0 0 1 1 1 1 Amino acid permease tRNA-synt_2d PF01409.20 KUM56894.1 - 1.8e-46 158.6 0.5 1.1e-22 80.7 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KUM56894.1 - 2.8e-27 95.0 0.0 1.2e-26 93.0 0.0 2.0 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Sin3_corepress PF08295.12 KUM56894.1 - 0.13 12.3 0.2 1.7 8.7 0.0 2.7 3 0 0 3 3 3 0 Sin3 family co-repressor Mito_carr PF00153.27 KUM56895.1 - 2.3e-16 59.5 2.0 1.5e-12 47.2 0.0 3.1 3 0 0 3 3 3 2 Mitochondrial carrier protein Macro PF01661.21 KUM56896.1 - 7.2e-41 138.9 0.0 9.4e-41 138.6 0.0 1.1 1 0 0 1 1 1 1 Macro domain Peptidase_S24 PF00717.23 KUM56897.1 - 3e-08 33.5 0.0 4.4e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 KUM56897.1 - 0.02 14.7 0.0 4.6 7.0 0.0 2.5 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 VSP PF03302.13 KUM56900.1 - 9.7e-05 21.4 2.9 9.7e-05 21.4 2.9 1.6 1 1 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.11 KUM56900.1 - 0.00078 19.6 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Podoplanin YebO PF13974.6 KUM56900.1 - 0.028 14.5 0.5 0.043 13.9 0.5 1.2 1 0 0 1 1 1 0 YebO-like protein Gram_pos_anchor PF00746.21 KUM56900.1 - 0.3 11.1 1.7 0.5 10.3 1.7 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Syndecan PF01034.20 KUM56900.1 - 0.45 10.5 1.4 0.79 9.7 1.4 1.3 1 0 0 1 1 1 0 Syndecan domain PH_4 PF15404.6 KUM56901.1 - 3.6e-54 183.3 0.3 3.1e-53 180.3 0.3 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.6 KUM56901.1 - 6e-24 83.5 0.5 1.5e-23 82.2 0.5 1.7 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.29 KUM56901.1 - 6.3e-12 45.9 0.1 0.00031 21.2 0.0 5.3 4 1 0 4 4 4 3 PH domain PH_6 PF15406.6 KUM56901.1 - 0.023 15.0 0.1 4.7 7.5 0.1 2.8 2 0 0 2 2 2 0 Pleckstrin homology domain DUF1654 PF07867.11 KUM56901.1 - 0.053 13.3 1.2 0.11 12.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) GLTP PF08718.11 KUM56902.1 - 8.6e-48 162.4 0.0 1.2e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Cir_N PF10197.9 KUM56902.1 - 0.028 14.6 0.1 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR FadA PF09403.10 KUM56902.1 - 0.39 11.2 2.4 0.47 11.0 0.2 2.1 2 0 0 2 2 2 0 Adhesion protein FadA DUF3924 PF13062.6 KUM56903.1 - 0.11 12.4 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) MT0933_antitox PF14013.6 KUM56903.1 - 3 8.2 10.6 55 4.2 10.6 2.7 1 1 0 1 1 1 0 MT0933-like antitoxin protein DUF1479 PF07350.12 KUM56904.1 - 3.4e-166 553.1 0.0 3.9e-166 552.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) DUF3759 PF12585.8 KUM56905.1 - 3e-39 132.9 10.9 3.5e-39 132.7 10.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) EXS PF03124.14 KUM56906.1 - 4e-97 325.5 36.2 5.1e-97 325.2 36.2 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KUM56906.1 - 2.1e-80 271.5 8.4 2.1e-80 271.5 8.4 1.4 2 0 0 2 2 2 1 SPX domain Aa_trans PF01490.18 KUM56907.1 - 6.9e-40 137.0 35.6 8.2e-40 136.8 35.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bax1-I PF01027.20 KUM56908.1 - 7.1e-51 173.0 29.3 8.1e-51 172.8 29.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spore_YhaL PF14147.6 KUM56908.1 - 0.2 11.4 1.2 0.52 10.0 0.3 2.2 2 0 0 2 2 2 0 Sporulation protein YhaL DUF1011 PF06237.12 KUM56908.1 - 1.7 9.0 11.0 13 6.2 2.3 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1011) Aa_trans PF01490.18 KUM56909.1 - 3.2e-93 312.7 13.0 4.4e-93 312.2 13.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KUM56909.1 - 2.9e-06 26.6 15.5 2.9e-06 26.6 15.5 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family adh_short PF00106.25 KUM56910.1 - 1e-36 126.2 0.0 1.3e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM56910.1 - 5.4e-30 104.7 0.0 8.6e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM56910.1 - 0.00013 21.9 0.0 0.0034 17.3 0.0 2.1 2 0 0 2 2 2 1 KR domain DcuA_DcuB PF03605.14 KUM56910.1 - 0.039 12.9 0.1 0.051 12.5 0.1 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DNA_ligase_A_C PF04679.15 KUM56910.1 - 0.12 13.0 0.2 0.32 11.6 0.0 1.7 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region DUF1776 PF08643.10 KUM56910.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RasGAP PF00616.19 KUM56912.1 - 4.9e-29 101.5 0.0 7.6e-20 71.5 0.0 2.6 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KUM56912.1 - 7.3e-07 29.4 0.0 7e-06 26.3 0.0 2.4 1 1 0 1 1 1 1 C2 domain Aminotran_1_2 PF00155.21 KUM56914.1 - 2e-40 139.1 0.0 2.4e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KUM56914.1 - 0.0099 14.4 0.0 0.025 13.1 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme WD40 PF00400.32 KUM56917.1 - 6.4e-08 33.1 0.5 2.7 9.0 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Glyco_hydro_17 PF00332.18 KUM56918.1 - 4.1e-07 29.9 0.0 2.6e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Glucan_synthase PF02364.15 KUM56919.1 - 0 1374.5 0.0 0 1374.0 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KUM56919.1 - 2.3e-43 147.6 1.1 6.5e-43 146.1 1.1 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 AMP-binding PF00501.28 KUM56920.1 - 5.6e-95 318.4 0.0 6.9e-95 318.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM56920.1 - 6.5e-15 55.9 1.0 1.4e-14 54.8 1.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_1 PF00583.25 KUM56921.1 - 1.1e-06 28.9 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KUM56921.1 - 0.00066 20.1 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KUM56921.1 - 0.007 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KUM56921.1 - 0.016 15.2 0.1 0.04 13.9 0.0 1.7 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Glyco_hydro_72 PF03198.14 KUM56922.1 - 1.4e-126 422.0 1.7 1.8e-126 421.7 1.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KUM56922.1 - 3.4e-05 23.4 0.0 0.0036 16.8 0.0 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PAP1 PF08601.10 KUM56922.1 - 2.1 8.0 15.8 3.6 7.2 15.8 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 RAP1 PF07218.11 KUM56922.1 - 4.2 5.5 18.4 5.8 5.1 18.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 KUM56922.1 - 9.7 4.6 8.5 13 4.2 8.5 1.2 1 0 0 1 1 1 0 Macoilin family F-box-like PF12937.7 KUM56923.1 - 1.2e-09 38.0 0.2 2.6e-09 36.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KUM56923.1 - 4.7e-08 32.7 0.5 1.1e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KUM56923.1 - 0.02 14.8 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 F-box UIM PF02809.20 KUM56923.1 - 0.025 14.5 5.3 2.6 8.2 0.3 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif Hira PF07569.11 KUM56923.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 TUP1-like enhancer of split AtuA PF07287.11 KUM56924.1 - 1.4e-125 418.6 0.1 1.7e-125 418.4 0.1 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Mre11_DNA_bind PF04152.14 KUM56925.1 - 3.2e-56 190.3 0.7 3.2e-56 190.3 0.7 2.2 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KUM56925.1 - 4.7e-14 53.4 2.3 4.8e-14 53.4 1.2 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KUM56925.1 - 0.0018 18.5 0.2 0.013 15.7 0.2 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ldh_1_C PF02866.18 KUM56926.1 - 2.6e-42 144.6 0.0 3.7e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KUM56926.1 - 4e-42 143.6 0.0 6e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KUM56926.1 - 4.5e-05 22.6 0.0 6.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 KUM56926.1 - 0.00016 21.3 0.7 0.2 11.2 0.0 2.4 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase Methyltransf_31 PF13847.6 KUM56927.1 - 7e-08 32.4 0.1 1.3e-05 25.1 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM56927.1 - 1.2e-06 28.5 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM56927.1 - 3.8e-06 27.5 0.0 0.00039 21.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KUM56927.1 - 5.3e-05 23.1 0.0 9.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 KUM56927.1 - 0.0077 17.2 0.0 0.016 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM56927.1 - 0.0092 16.7 0.0 0.026 15.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KUM56927.1 - 0.026 14.6 0.0 0.042 14.0 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.20 KUM56927.1 - 0.037 13.3 0.1 0.059 12.7 0.1 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KUM56927.1 - 0.043 14.5 0.1 0.25 12.0 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KUM56927.1 - 0.061 12.7 0.0 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 KUM56927.1 - 0.079 11.9 0.0 0.58 9.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) IGPD PF00475.18 KUM56929.1 - 6.8e-56 188.6 0.6 9.3e-56 188.1 0.6 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Arena_RNA_pol PF06317.11 KUM56929.1 - 0.35 8.0 0.0 0.46 7.6 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase Abhydrolase_1 PF00561.20 KUM56930.1 - 8.8e-11 41.9 0.0 2.8e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM56930.1 - 1.6e-08 34.1 0.0 1.4e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 zf-TFIIIC PF12660.7 KUM56931.1 - 0.17 11.9 0.2 0.17 11.9 0.2 1.6 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex DER1 PF04511.15 KUM56934.1 - 2.7e-49 167.7 5.8 3.2e-49 167.5 5.8 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 KUM56934.1 - 0.2 11.6 5.6 0.31 11.0 5.6 1.3 1 0 0 1 1 1 0 Rhomboid family Gly_transf_sug PF04488.15 KUM56935.1 - 2.2e-19 69.9 0.0 3.7e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Cohesin_load PF10345.9 KUM56936.1 - 2e-176 588.0 6.4 2.3e-176 587.8 6.4 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 KUM56936.1 - 0.21 11.9 20.9 0.21 11.9 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat HTH_WhiA PF02650.14 KUM56936.1 - 0.58 10.5 2.2 1.8 8.9 0.4 2.3 2 0 0 2 2 2 0 WhiA C-terminal HTH domain Histone PF00125.24 KUM56937.1 - 3e-42 144.1 0.3 3.6e-42 143.8 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KUM56937.1 - 6.1e-05 23.1 0.6 9.8e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KUM56937.1 - 0.00083 19.7 0.1 0.0015 18.9 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KUM56937.1 - 0.012 15.9 0.5 0.026 14.8 0.5 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KUM56937.1 - 0.083 13.0 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Complex1_LYR_2 PF13233.6 KUM56939.1 - 3.4e-06 27.7 0.1 4.5e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KUM56939.1 - 7.4e-05 22.7 0.0 0.00014 21.9 0.0 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) IKKbetaNEMObind PF12179.8 KUM56939.1 - 0.025 14.6 0.0 0.78 9.8 0.0 2.3 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Aldo_ket_red PF00248.21 KUM56941.1 - 1.3e-43 149.3 0.0 8e-42 143.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Nefa_Nip30_N PF10187.9 KUM56942.1 - 2.4e-31 108.2 14.6 2.4e-31 108.2 14.6 1.8 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Sugar_tr PF00083.24 KUM56943.1 - 9e-105 351.1 18.5 1e-104 350.9 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM56943.1 - 2.3e-33 115.6 24.6 8.4e-25 87.4 3.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 KUM56943.1 - 0.85 9.5 2.5 3.8 7.4 0.0 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Bac_luciferase PF00296.20 KUM56945.1 - 8.5e-69 232.4 0.0 1e-68 232.1 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Alpha-L-AF_C PF06964.12 KUM56946.1 - 2.6e-31 109.0 0.3 3.7e-31 108.5 0.3 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain p450 PF00067.22 KUM56947.1 - 1.1e-53 182.7 0.0 1.2e-53 182.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phage_HK97_TLTM PF06120.11 KUM56949.1 - 0.34 10.1 0.5 0.49 9.5 0.5 1.1 1 0 0 1 1 1 0 Tail length tape measure protein DUF3716 PF12511.8 KUM56950.1 - 1e-09 38.3 5.0 1.9e-09 37.5 5.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Cation_ATPase_C PF00689.21 KUM56951.1 - 4e-47 160.3 8.1 4e-47 160.3 8.1 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KUM56951.1 - 6.4e-39 133.3 0.3 6.4e-39 133.3 0.3 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KUM56951.1 - 1.1e-20 73.5 0.0 2.1e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KUM56951.1 - 1.4e-19 71.2 0.5 7.6e-19 68.8 0.5 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KUM56951.1 - 1.2e-08 34.5 0.2 4.4e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KUM56951.1 - 1.1e-05 25.3 2.0 0.00014 21.7 1.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Tannase PF07519.11 KUM56952.1 - 7.6e-103 344.9 1.7 8.9e-103 344.7 1.7 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KUM56952.1 - 0.023 14.2 0.4 3.1 7.2 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family D-ser_dehydrat PF14031.6 KUM56953.1 - 1.4e-23 83.3 0.1 3.3e-23 82.2 0.1 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KUM56953.1 - 1.1e-11 44.8 0.0 1.6e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Rad60-SLD PF11976.8 KUM56954.1 - 2.1e-20 72.3 0.2 2.5e-20 72.1 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KUM56954.1 - 2.8e-11 43.0 0.1 3.3e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Nup84_Nup100 PF04121.13 KUM56955.1 - 3.9e-171 570.8 0.1 5.4e-171 570.3 0.1 1.2 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 LpqV PF17301.2 KUM56955.1 - 0.098 12.9 0.1 0.28 11.4 0.1 1.7 1 0 0 1 1 1 0 Putative lipoprotein LpqV DUF2203 PF09969.9 KUM56955.1 - 0.43 11.3 3.0 1.1 10.0 0.4 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) AAA_18 PF13238.6 KUM56956.1 - 0.00014 22.4 0.0 0.00064 20.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KUM56956.1 - 0.00056 20.3 0.0 0.001 19.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KUM56956.1 - 0.0027 18.0 0.0 0.0043 17.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KUM56956.1 - 0.0097 16.1 0.0 0.013 15.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 KUM56956.1 - 0.027 14.3 0.0 3.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 KUM56956.1 - 0.096 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PBP_sp32 PF07222.12 KUM56958.1 - 0.02 14.3 1.1 0.032 13.7 1.1 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Jak1_Phl PF17887.1 KUM56958.1 - 0.036 14.1 2.3 0.054 13.5 2.3 1.2 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain MTCP1 PF08991.10 KUM56959.1 - 3e-21 75.4 5.7 3e-21 75.4 5.7 1.5 2 0 0 2 2 2 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KUM56959.1 - 0.037 14.2 6.1 0.037 14.2 6.1 1.8 2 0 0 2 2 2 0 CHCH domain Nipped-B_C PF12830.7 KUM56960.1 - 1.4e-46 158.8 3.9 4.7e-45 153.9 1.6 2.9 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KUM56960.1 - 8.4e-13 48.4 0.3 3.6e-12 46.4 0.3 2.2 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 KUM56960.1 - 9.3e-05 22.5 1.6 0.0053 16.8 0.0 3.5 2 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 KUM56960.1 - 0.00065 19.0 3.7 0.27 10.4 0.0 4.5 5 0 0 5 5 5 2 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 KUM56960.1 - 0.0024 18.0 0.5 2 8.9 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Sec7_N PF12783.7 KUM56960.1 - 0.0033 17.3 0.2 1 9.2 0.0 4.4 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal MA3 PF02847.17 KUM56960.1 - 0.0036 17.3 0.4 3.9 7.5 0.0 4.0 4 0 0 4 4 4 1 MA3 domain CLAMP PF14769.6 KUM56960.1 - 0.089 13.3 0.1 0.33 11.4 0.1 2.0 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 CLTH PF10607.9 KUM56961.1 - 1.4e-31 109.4 0.0 1.8e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KUM56961.1 - 1.4e-09 37.5 0.0 2.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 LisH HU-HIG PF18291.1 KUM56961.1 - 0.089 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 HU domain fused to wHTH, Ig, or Glycine-rich motif Pyr_redox_2 PF07992.14 KUM56962.1 - 1.6e-42 145.8 0.0 2.2e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM56962.1 - 8.1e-13 48.7 0.0 1.5e-10 41.4 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 KUM56962.1 - 5.1e-05 23.6 0.0 0.00011 22.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KUM56962.1 - 7e-05 22.1 0.1 0.00021 20.6 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KUM56962.1 - 0.00058 19.6 0.1 0.0016 18.2 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KUM56962.1 - 0.0047 16.4 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 EF hand TFIIS_C PF01096.18 KUM56963.1 - 3.9e-13 49.0 3.1 3.9e-13 49.0 3.1 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KUM56963.1 - 2.7e-05 24.0 0.5 2.7e-05 24.0 0.5 2.7 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 KUM56963.1 - 0.0021 18.1 2.2 0.12 12.4 0.1 2.5 2 0 0 2 2 2 1 Double zinc ribbon Zn_ribbon_recom PF13408.6 KUM56963.1 - 0.052 14.1 6.9 0.26 11.8 0.0 2.6 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain C1_1 PF00130.22 KUM56963.1 - 0.058 13.3 2.4 0.11 12.4 0.1 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2072 PF09845.9 KUM56963.1 - 0.14 12.4 1.4 1.5 9.1 1.4 2.0 1 1 0 1 1 1 0 Zn-ribbon containing protein zf-ribbon_3 PF13248.6 KUM56963.1 - 0.14 11.6 4.2 21 4.7 0.0 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KUM56963.1 - 0.24 11.2 7.5 3.6 7.4 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-trcl PF13451.6 KUM56963.1 - 0.31 11.0 4.5 2.4 8.1 0.1 3.1 3 0 0 3 3 3 0 Probable zinc-ribbon domain Nudix_N_2 PF14803.6 KUM56963.1 - 0.76 9.7 7.6 12 5.9 0.1 3.5 3 1 0 3 3 3 0 Nudix N-terminal zf-RING_7 PF02591.15 KUM56963.1 - 1.3 9.3 5.2 44 4.4 0.1 3.8 3 1 1 4 4 4 0 C4-type zinc ribbon domain zf-IS66 PF13005.7 KUM56963.1 - 8.8 6.8 10.1 41 4.7 0.0 3.8 4 0 0 4 4 3 0 zinc-finger binding domain of transposase IS66 HEAT_2 PF13646.6 KUM56965.1 - 9.7e-28 96.4 1.2 8.1e-12 45.4 0.0 3.7 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 KUM56965.1 - 2.7e-16 58.5 0.7 0.013 16.1 0.3 6.6 8 0 0 8 8 8 4 PBS lyase HEAT-like repeat HEAT PF02985.22 KUM56965.1 - 8.2e-10 38.1 1.5 1.2 9.6 0.0 5.6 7 0 0 7 7 7 3 HEAT repeat Cnd1 PF12717.7 KUM56965.1 - 0.00067 19.7 0.0 0.2 11.7 0.0 2.8 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 KUM56965.1 - 0.004 17.4 0.0 0.73 10.2 0.0 2.6 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 KUM56965.1 - 0.022 15.3 6.1 22 5.7 0.0 5.0 4 1 1 5 5 5 0 HEAT-like repeat RuvA_C PF07499.13 KUM56965.1 - 0.052 14.0 3.1 6.6 7.3 0.3 3.2 3 0 0 3 3 3 0 RuvA, C-terminal domain PRK PF00485.18 KUM56966.1 - 5.6e-58 195.9 0.0 7.8e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KUM56966.1 - 2.4e-40 138.2 0.0 4.2e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 KUM56966.1 - 3.3e-07 30.9 0.0 9.6e-06 26.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain CPT PF07931.12 KUM56966.1 - 3.5e-05 23.7 0.0 8.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 KUM56966.1 - 0.003 17.3 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase AAA_17 PF13207.6 KUM56966.1 - 0.0037 17.7 0.3 0.24 11.8 0.4 3.0 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KUM56966.1 - 0.0037 16.6 0.0 0.01 15.1 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 KUM56966.1 - 0.0042 17.2 0.0 0.008 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Pribosyltran PF00156.27 KUM56966.1 - 0.02 14.4 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosyl transferase domain DUF87 PF01935.17 KUM56966.1 - 0.03 14.4 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain APS_kinase PF01583.20 KUM56966.1 - 0.043 13.7 0.3 0.72 9.7 0.0 2.7 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_16 PF13191.6 KUM56966.1 - 0.076 13.4 0.0 0.32 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KUM56966.1 - 0.14 12.6 0.4 0.58 10.7 0.2 2.0 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.22 KUM56966.1 - 0.21 10.7 0.2 0.52 9.4 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain NUC153 PF08159.12 KUM56967.1 - 5.9e-14 51.6 9.8 1.5e-12 47.1 0.8 3.7 3 0 0 3 3 3 3 NUC153 domain p450 PF00067.22 KUM56968.1 - 7.6e-77 259.0 0.0 1e-76 258.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 KUM56969.1 - 5.7e-08 32.0 4.0 1.2e-07 30.9 0.4 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain adh_short PF00106.25 KUM56970.1 - 2.1e-08 33.8 0.0 8.5e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KUM56970.1 - 0.0012 18.8 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KUM56970.1 - 0.0023 17.5 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase IDH PF03971.14 KUM56970.1 - 0.22 9.9 0.0 0.31 9.4 0.0 1.1 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase NmrA PF05368.13 KUM56971.1 - 3.1e-14 53.1 0.1 4.4e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM56971.1 - 0.00031 20.7 0.0 0.00065 19.6 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KUM56971.1 - 0.086 13.3 0.2 0.29 11.6 0.2 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KCH PF16944.5 KUM56972.1 - 8.6e-100 333.6 5.2 1e-99 333.4 5.2 1.0 1 0 0 1 1 1 1 Fungal potassium channel DUF747 PF05346.11 KUM56975.1 - 1.7e-117 392.5 3.2 2.2e-117 392.1 3.2 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Curto_V2 PF07325.11 KUM56976.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Curtovirus V2 protein PNP_UDP_1 PF01048.20 KUM56977.1 - 2.6e-39 134.9 0.1 3.2e-39 134.6 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4291 PF14124.6 KUM56979.1 - 6.2e-74 247.8 0.1 7e-74 247.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Epimerase PF01370.21 KUM56980.1 - 2.8e-13 49.9 0.0 5.3e-13 49.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KUM56980.1 - 8.9e-13 47.9 0.0 1.2e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KUM56980.1 - 1.3e-09 38.2 0.0 2.1e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KUM56980.1 - 2.6e-08 33.3 0.1 7.4e-05 22.0 0.0 2.2 1 1 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KUM56980.1 - 7.7e-08 32.1 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KUM56980.1 - 0.00013 21.6 0.1 0.0002 21.0 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KUM56980.1 - 0.00019 20.6 0.0 0.00029 20.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KUM56980.1 - 0.004 16.3 0.0 0.067 12.3 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 KUM56980.1 - 0.17 11.8 0.1 20 5.0 0.0 2.2 2 0 0 2 2 2 0 KR domain TAFII55_N PF04658.13 KUM56981.1 - 1.6e-48 164.5 0.1 7.3e-48 162.3 0.0 2.1 2 0 0 2 2 2 1 TAFII55 protein conserved region AAA_32 PF13654.6 KUM56981.1 - 0.027 13.3 4.8 0.041 12.7 4.8 1.2 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 KUM56981.1 - 2.9 7.2 7.6 4.1 6.7 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ofd1_CTDD PF10637.9 KUM56982.1 - 1.9e-98 328.9 0.0 1.5e-94 316.2 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KUM56982.1 - 7.8e-25 87.4 0.0 1.8e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KUM56982.1 - 2.6e-13 50.6 0.0 5.6e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BUD22 PF09073.10 KUM56982.1 - 5.8 6.1 13.5 13 5.0 13.5 1.6 1 0 0 1 1 1 0 BUD22 Ank_2 PF12796.7 KUM56983.1 - 5.3e-15 55.8 0.8 2.9e-06 27.8 0.1 5.8 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM56983.1 - 1.7e-10 41.2 5.7 1.5 9.5 0.0 7.2 7 1 1 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM56983.1 - 2.5e-05 24.4 6.4 1.2 9.5 0.0 6.9 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM56983.1 - 0.00011 22.4 9.6 25 5.9 0.1 7.8 9 1 0 9 9 9 1 Ankyrin repeat Ank PF00023.30 KUM56983.1 - 0.015 15.7 13.2 3.7 8.2 0.7 6.7 7 1 0 7 7 7 0 Ankyrin repeat ECH_1 PF00378.20 KUM56985.1 - 1.7e-20 73.4 0.0 1.9e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KUM56985.1 - 8e-05 22.3 0.0 0.00013 21.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KUM56985.1 - 0.022 14.7 0.0 5.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 ADH_zinc_N PF00107.26 KUM56986.1 - 2.5e-22 79.2 0.1 4e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM56986.1 - 7.6e-21 74.0 0.6 2.1e-20 72.6 0.4 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KUM56986.1 - 0.00086 20.4 0.0 0.0017 19.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MinC_N PF05209.13 KUM56986.1 - 0.0024 17.8 0.0 0.0089 16.0 0.0 1.9 2 0 0 2 2 2 1 Septum formation inhibitor MinC, N-terminal domain ASF1_hist_chap PF04729.13 KUM56986.1 - 0.058 13.3 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 ASF1 like histone chaperone PEP_mutase PF13714.6 KUM56986.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase DDHD PF02862.17 KUM56991.1 - 0.19 11.8 5.4 0.22 11.7 5.4 1.2 1 0 0 1 1 1 0 DDHD domain Tim54 PF11711.8 KUM56991.1 - 0.38 9.5 19.4 0.44 9.3 19.4 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Caldesmon PF02029.15 KUM56991.1 - 1.1 8.0 38.5 1.3 7.7 38.5 1.1 1 0 0 1 1 1 0 Caldesmon Nop14 PF04147.12 KUM56991.1 - 2.1 6.5 50.3 2.9 6.0 50.3 1.2 1 0 0 1 1 1 0 Nop14-like family Dynactin_p62 PF05502.13 KUM56991.1 - 2.7 6.7 12.1 3.4 6.3 12.1 1.1 1 0 0 1 1 1 0 Dynactin p62 family Peptidase_S64 PF08192.11 KUM56991.1 - 2.8 6.3 7.9 3.1 6.2 7.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Lin-8 PF03353.15 KUM56991.1 - 2.9 7.4 30.2 3.8 7.0 30.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Coilin_N PF15862.5 KUM56991.1 - 3.1 7.6 14.1 5.9 6.7 14.1 1.5 1 0 0 1 1 1 0 Coilin N-terminus Sec62 PF03839.16 KUM56991.1 - 3.3 7.2 10.4 4.5 6.7 10.4 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 SLC12 PF03522.15 KUM56991.1 - 3.5 6.5 12.1 3.8 6.4 12.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CLN3 PF02487.17 KUM56991.1 - 3.9 6.4 7.6 4.2 6.3 7.6 1.2 1 0 0 1 1 1 0 CLN3 protein DUF4045 PF13254.6 KUM56991.1 - 3.9 7.0 13.1 4.2 6.9 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF913 PF06025.12 KUM56991.1 - 4.3 6.2 12.8 4.6 6.1 12.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2828 PF11443.8 KUM56991.1 - 6.9 4.6 10.3 7.6 4.5 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) BUD22 PF09073.10 KUM56991.1 - 7.9 5.7 45.1 10 5.3 45.1 1.2 1 0 0 1 1 1 0 BUD22 PIP5K PF01504.18 KUM56991.1 - 8 5.6 12.8 8.3 5.5 12.1 1.3 1 1 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase MTS PF05175.14 KUM56992.1 - 6.5e-07 29.1 0.0 0.00049 19.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 KUM56992.1 - 2.9e-06 27.2 0.0 4.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM56992.1 - 6.5e-05 23.6 0.0 0.00017 22.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 KUM56992.1 - 0.0042 16.4 0.0 0.034 13.5 0.0 2.0 2 0 0 2 2 2 1 RNA methyltransferase Ubie_methyltran PF01209.18 KUM56992.1 - 0.005 16.2 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KUM56992.1 - 0.005 16.7 0.0 0.0093 15.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain AviRa PF11599.8 KUM56992.1 - 0.02 14.4 0.0 0.051 13.0 0.0 1.8 1 1 0 1 1 1 0 RRNA methyltransferase AviRa PrmA PF06325.13 KUM56992.1 - 0.05 13.0 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KUM56992.1 - 0.094 13.5 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 KUM56992.1 - 0.17 11.5 0.0 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 KUM56992.1 - 0.18 12.5 0.0 0.34 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.16 KUM56992.1 - 0.19 11.0 0.0 0.72 9.1 0.0 1.8 1 1 0 1 1 1 0 N-6 DNA Methylase Methyltransf_16 PF10294.9 KUM56992.1 - 0.21 11.3 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Asp PF00026.23 KUM56993.1 - 4.6e-70 236.5 8.6 5.6e-70 236.3 8.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KUM56993.1 - 7.9e-11 42.5 8.5 2.4e-10 40.9 5.6 3.0 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KUM56993.1 - 3.5e-07 30.8 0.4 0.27 11.9 0.0 3.6 3 0 0 3 3 3 3 Aspartyl protease TAXi_C PF14541.6 KUM56993.1 - 0.00054 19.8 0.1 0.014 15.2 0.0 2.8 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KUM56993.1 - 0.00066 20.2 0.0 5.9 7.5 0.0 3.9 2 2 0 2 2 2 2 gag-polyprotein putative aspartyl protease Fcf2 PF08698.11 KUM56994.1 - 1.6e-37 127.8 1.8 2.5e-37 127.1 0.4 2.0 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing CBFD_NFYB_HMF PF00808.23 KUM56995.1 - 7e-13 48.7 0.2 1e-12 48.1 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KUM56995.1 - 2.7e-10 40.7 0.1 4.4e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KUM56995.1 - 0.046 14.0 0.0 0.071 13.4 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Etmic-2 PF06670.11 KUM56995.1 - 0.071 12.0 0.0 0.087 11.7 0.0 1.1 1 0 0 1 1 1 0 Microneme protein Etmic-2 Sec15 PF04091.12 KUM56996.1 - 3.7e-107 358.4 2.0 8.1e-107 357.3 2.0 1.6 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 KUM56996.1 - 0.00017 21.5 0.8 0.00017 21.5 0.8 2.7 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 KUM56996.1 - 0.0031 17.6 1.5 0.0031 17.6 1.5 3.0 3 1 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 KUM56996.1 - 0.0065 16.7 2.7 0.0065 16.7 2.7 2.9 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Sec5 PF15469.6 KUM56996.1 - 0.0075 16.1 7.0 0.039 13.8 2.2 3.1 3 0 0 3 3 3 1 Exocyst complex component Sec5 DUF3510 PF12022.8 KUM56996.1 - 0.016 15.6 3.9 1.5 9.2 0.0 3.6 2 2 0 3 3 3 0 Domain of unknown function (DUF3510) Mre11_DNA_bind PF04152.14 KUM56996.1 - 0.044 14.1 1.0 0.29 11.4 0.0 2.7 2 0 0 2 2 2 0 Mre11 DNA-binding presumed domain Vps51 PF08700.11 KUM56996.1 - 0.048 13.7 1.7 0.23 11.5 0.2 2.8 2 0 0 2 2 2 0 Vps51/Vps67 ApoLp-III PF07464.11 KUM56996.1 - 0.17 11.9 7.7 1.1 9.4 0.6 3.4 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Vps54_N PF10475.9 KUM56996.1 - 0.18 11.1 7.4 0.094 12.0 2.6 2.2 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex PNP_UDP_1 PF01048.20 KUM56998.1 - 1.1e-26 93.5 0.1 1.3e-26 93.3 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily PNP_UDP_1 PF01048.20 KUM56999.1 - 2e-12 46.9 0.2 3.7e-12 46.0 0.2 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily WD40 PF00400.32 KUM57000.1 - 2.9e-63 208.3 11.1 1.8e-09 38.0 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM57000.1 - 5.6e-21 74.6 0.0 0.00015 21.9 0.0 6.5 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 KUM57000.1 - 2.1e-18 66.4 10.0 3.5e-18 65.7 10.0 1.4 1 0 0 1 1 1 1 Tup N-terminal WD40_like PF17005.5 KUM57000.1 - 2.2e-07 30.5 0.0 0.34 10.2 0.0 4.4 4 1 2 6 6 6 3 WD40-like domain Ge1_WD40 PF16529.5 KUM57000.1 - 8.1e-07 28.3 0.1 0.22 10.5 0.0 4.9 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KUM57000.1 - 1.9e-05 23.4 0.4 0.00027 19.6 0.2 2.5 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 KUM57000.1 - 5.6e-05 22.0 0.1 0.3 9.7 0.0 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KUM57000.1 - 0.0004 20.3 0.0 0.025 14.5 0.0 2.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KUM57000.1 - 0.035 13.4 0.0 6.2 6.1 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KUM57000.1 - 0.066 13.2 0.0 12 6.0 0.0 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat TPX2 PF06886.11 KUM57000.1 - 2 8.7 5.8 4.3 7.7 5.8 1.5 1 1 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) UPF0242 PF06785.11 KUM57000.1 - 2.2 8.4 6.7 3.3 7.8 6.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FA_hydroxylase PF04116.13 KUM57001.1 - 7.9e-24 84.5 21.0 8.8e-24 84.4 15.7 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily tRNA-synt_1b PF00579.25 KUM57002.1 - 5.3e-73 245.9 0.0 7.2e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) LPP PF04728.13 KUM57002.1 - 0.14 12.5 0.1 0.34 11.3 0.1 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Ribosomal_S10 PF00338.22 KUM57003.1 - 3.1e-28 97.9 0.0 5.2e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DAHP_synth_1 PF00793.20 KUM57003.1 - 0.2 10.5 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 DAHP synthetase I family CCDC71L PF15374.6 KUM57003.1 - 0.45 9.7 3.4 0.63 9.3 3.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L FAP PF07174.11 KUM57003.1 - 2.6 7.4 22.0 3.7 6.9 22.0 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) WD40 PF00400.32 KUM57004.1 - 5.2e-41 137.9 19.8 1.9e-09 38.0 0.5 12.6 13 0 0 13 13 13 6 WD domain, G-beta repeat Utp12 PF04003.12 KUM57004.1 - 6.9e-28 97.1 0.0 1.1e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KUM57004.1 - 4.7e-26 90.9 0.0 0.00043 20.5 0.0 10.7 5 2 5 12 12 12 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KUM57004.1 - 1.7e-09 37.1 0.9 0.074 12.0 0.0 4.7 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KUM57004.1 - 7.5e-08 32.5 3.2 0.025 14.4 0.1 6.5 6 2 1 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KUM57004.1 - 2.4e-05 23.2 5.4 3.7 6.1 0.0 5.4 2 2 3 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KUM57004.1 - 0.00047 19.6 0.0 0.24 10.7 0.0 3.7 4 1 1 5 5 5 1 WD40-like domain Nbas_N PF15492.6 KUM57004.1 - 0.0035 16.7 0.3 3.9 6.7 0.0 3.6 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.6 KUM57004.1 - 0.0061 17.0 3.3 5 7.7 0.1 5.6 7 0 0 7 7 5 1 PQQ-like domain PD40 PF07676.12 KUM57004.1 - 0.02 14.9 0.2 12 5.9 0.0 4.5 6 0 0 6 6 5 0 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 KUM57004.1 - 0.036 13.1 0.7 2.8 7.0 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Coatomer_WDAD PF04053.14 KUM57004.1 - 0.076 12.0 0.0 7.8 5.4 0.0 3.2 3 1 0 3 3 3 0 Coatomer WD associated region PALB2_WD40 PF16756.5 KUM57004.1 - 0.14 11.1 0.1 11 4.9 0.0 3.0 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain RAB3GAP2_N PF14655.6 KUM57004.1 - 0.15 11.3 0.2 3.9 6.6 0.0 3.1 3 1 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DivIVA PF05103.13 KUM57006.1 - 0.51 10.4 9.1 6.7 6.8 5.1 2.4 1 1 1 2 2 2 0 DivIVA protein Mpp10 PF04006.12 KUM57006.1 - 1.7 7.0 23.9 1.1 7.6 8.3 2.1 2 0 0 2 2 2 0 Mpp10 protein SDA1 PF05285.12 KUM57006.1 - 4.4 6.6 23.1 0.37 10.2 10.0 2.1 2 0 0 2 2 2 0 SDA1 Pkinase PF00069.25 KUM57007.1 - 1.7e-69 234.1 0.0 2.2e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM57007.1 - 1.9e-34 119.1 0.0 3.3e-34 118.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM57007.1 - 0.0045 16.3 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KUM57007.1 - 0.033 13.0 0.0 0.092 11.5 0.0 1.7 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KUM57007.1 - 0.11 11.9 0.3 0.21 10.9 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GTP_cyclohydroI PF01227.22 KUM57008.1 - 4e-73 244.6 0.7 5.6e-73 244.2 0.7 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KUM57008.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 QueF-like protein CAF1C_H4-bd PF12265.8 KUM57009.1 - 6.7e-29 100.0 0.8 3.1e-28 97.8 0.8 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KUM57009.1 - 7.8e-26 89.8 11.9 5.2e-06 27.1 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM57009.1 - 1.3e-05 25.4 0.6 0.25 11.7 0.0 4.4 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KUM57009.1 - 0.017 13.8 0.5 5.9 5.4 0.2 3.5 2 1 0 3 3 3 0 Nucleoporin Nup120/160 DUF3751 PF12571.8 KUM57009.1 - 0.024 14.7 0.0 2.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Phage tail-collar fibre protein XRN_M PF17846.1 KUM57010.1 - 1.5e-101 340.6 5.3 2.3e-101 340.0 5.3 1.2 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KUM57010.1 - 1.2e-96 322.9 0.0 1.2e-96 322.9 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KUM57010.1 - 3.4e-74 248.8 0.2 7.6e-74 247.6 0.0 1.7 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KUM57010.1 - 2.6e-32 110.9 0.0 7.6e-32 109.4 0.0 1.9 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KUM57010.1 - 9.1e-24 83.4 0.3 2e-23 82.3 0.3 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KUM57010.1 - 1.6e-06 28.1 0.1 5.5e-06 26.4 0.1 2.0 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 DUF1345 PF07077.11 KUM57010.1 - 0.14 11.8 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) p450 PF00067.22 KUM57011.1 - 2.8e-32 112.1 0.0 9.9e-32 110.3 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 LptC PF06835.13 KUM57012.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide-assembly, LptC-related MTHFR_C PF12225.8 KUM57013.1 - 0.06 13.0 1.0 0.15 11.7 1.0 1.6 1 1 1 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal MFS_1 PF07690.16 KUM57014.1 - 2.3e-21 76.1 20.3 2.3e-21 76.1 20.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KUM57014.1 - 1.5e-06 27.7 1.3 1.5e-06 27.7 1.3 2.1 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Dimer_Tnp_hAT PF05699.14 KUM57015.1 - 7.5e-13 48.1 0.0 2.5e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MPP6 PF10175.9 KUM57015.1 - 0.95 10.0 4.1 1.6 9.2 4.1 1.3 1 0 0 1 1 1 0 M-phase phosphoprotein 6 Sugar_tr PF00083.24 KUM57016.1 - 1e-67 229.0 24.6 1.2e-67 228.8 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM57016.1 - 1.4e-09 37.3 37.1 2.6e-09 36.5 31.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KUM57016.1 - 3.8e-05 22.4 18.1 0.0019 16.9 3.3 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KUM57016.1 - 1.3 7.8 16.8 0.033 13.1 7.2 2.4 2 1 0 2 2 2 0 MFS_1 like family BNR_2 PF13088.6 KUM57017.1 - 8e-21 74.6 0.1 1.7e-19 70.2 0.1 2.0 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KUM57017.1 - 3.9e-06 26.0 21.4 0.17 12.0 0.3 6.3 6 0 0 6 6 6 3 BNR/Asp-box repeat DUF4185 PF13810.6 KUM57017.1 - 0.00067 19.0 1.1 0.048 12.9 0.0 3.2 3 1 1 4 4 4 1 Domain of unknown function (DUF4185) Sortilin-Vps10 PF15902.5 KUM57017.1 - 0.0045 15.8 4.6 1.5 7.6 0.1 3.6 2 2 1 3 3 3 3 Sortilin, neurotensin receptor 3, CHB_HEX_C PF03174.13 KUM57017.1 - 0.029 14.4 1.7 4.4 7.3 0.0 4.1 4 0 0 4 4 4 0 Chitobiase/beta-hexosaminidase C-terminal domain Peptidase_M24 PF00557.24 KUM57018.1 - 2.5e-46 158.0 0.0 4.7e-46 157.1 0.0 1.4 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KUM57018.1 - 6e-06 27.0 0.0 2.6e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Sugar_tr PF00083.24 KUM57019.1 - 4.5e-32 111.5 30.5 1e-16 60.9 8.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KUM57019.1 - 6.6e-25 87.8 49.2 2e-12 46.7 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Hydrophobin PF01185.18 KUM57020.1 - 2.5e-05 24.8 4.8 6.7e-05 23.4 4.9 1.6 1 1 1 2 2 2 2 Fungal hydrophobin NAD_binding_1 PF00175.21 KUM57021.1 - 5.4e-26 91.4 0.0 8.3e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KUM57021.1 - 2.7e-17 63.0 0.0 4.2e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KUM57021.1 - 2.1e-07 31.2 0.0 2.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Aldo_ket_red PF00248.21 KUM57022.1 - 1.7e-64 217.9 0.0 2.1e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HMG_CoA_synt_C PF08540.10 KUM57023.1 - 1.1e-98 330.3 1.6 1.4e-98 330.0 1.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KUM57023.1 - 4.1e-86 287.3 0.1 6e-86 286.7 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Mur_ligase_C PF02875.21 KUM57023.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain bZIP_1 PF00170.21 KUM57024.1 - 0.0007 19.6 11.7 0.0023 18.0 11.7 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KUM57024.1 - 0.016 15.3 5.6 0.016 15.3 5.6 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Kinesin_assoc PF16183.5 KUM57024.1 - 0.11 12.7 0.3 1.4 9.0 0.3 2.1 1 1 0 1 1 1 0 Kinesin-associated TEX13 PF15186.6 KUM57024.1 - 0.21 11.2 5.8 0.33 10.6 5.8 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family UPF0688 PF15772.5 KUM57024.1 - 3.1 8.0 11.1 0.086 13.1 1.3 2.1 1 1 0 2 2 2 0 UPF0688 family eIF-3_zeta PF05091.12 KUM57025.1 - 1.1e-205 684.6 0.0 1.3e-205 684.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3546 PF12066.8 KUM57026.1 - 1.5e-31 108.8 2.3 1.5e-31 108.8 2.3 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KUM57026.1 - 1.8e-12 48.1 2.6 1.9e-12 48.0 0.1 2.4 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 KUM57026.1 - 2.5e-12 46.4 0.1 5.8e-12 45.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) PAD_porph PF04371.15 KUM57028.1 - 5.7e-95 318.3 0.0 7.1e-95 318.0 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase SinI PF08671.10 KUM57028.1 - 0.079 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Anti-repressor SinI DUF881 PF05949.12 KUM57028.1 - 0.14 12.0 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) MFS_1 PF07690.16 KUM57029.1 - 1.3e-40 139.5 39.3 5.2e-31 107.9 21.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KUM57029.1 - 0.09 11.0 12.9 0.38 9.0 7.7 3.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Trp_oprn_chp PF09534.10 KUM57029.1 - 8.1 6.2 8.3 3.9 7.2 3.2 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ribosomal_L13 PF00572.18 KUM57031.1 - 4.1e-43 146.6 0.0 5.2e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.18 KUM57033.1 - 3.2e-77 257.1 0.7 1.1e-41 142.2 0.2 2.1 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.19 KUM57033.1 - 0.0066 16.3 0.0 0.016 15.0 0.0 1.6 2 0 0 2 2 2 1 Plasmid recombination enzyme Phos_pyr_kin PF08543.12 KUM57034.1 - 5.7e-83 278.1 0.4 7.7e-83 277.6 0.4 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KUM57034.1 - 1.2e-49 168.9 0.4 1.7e-49 168.5 0.4 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KUM57034.1 - 1e-07 31.6 0.3 1.6e-06 27.7 0.3 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 KUM57034.1 - 0.00016 21.2 1.2 0.00041 19.9 0.3 1.9 2 0 0 2 2 2 1 Carbohydrate kinase HK PF02110.15 KUM57034.1 - 0.00067 19.1 0.6 0.12 11.7 0.1 2.3 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family Ribosomal_S9 PF00380.19 KUM57036.1 - 3.5e-33 114.7 0.8 4e-33 114.5 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 PilJ PF13675.6 KUM57036.1 - 0.049 13.7 0.2 0.073 13.1 0.2 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DNA_pol_B PF00136.21 KUM57037.1 - 5.3e-118 394.6 1.6 7.4e-118 394.2 1.6 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KUM57037.1 - 3.8e-69 232.2 1.6 8.2e-69 231.0 1.6 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KUM57037.1 - 4.9e-43 147.5 0.0 1.3e-42 146.2 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KUM57037.1 - 1.4e-23 82.7 13.0 1.7e-23 82.5 7.0 3.0 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal NCKAP5 PF15246.6 KUM57037.1 - 0.049 13.3 1.3 0.11 12.1 1.3 1.5 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein DEAD PF00270.29 KUM57038.1 - 2.6e-46 157.6 0.1 4.6e-46 156.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM57038.1 - 1.5e-23 83.2 0.0 1.1e-22 80.5 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KUM57038.1 - 7.7e-18 64.5 0.1 1.4e-17 63.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KUM57038.1 - 5.2e-05 23.3 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KUM57038.1 - 0.00077 18.8 0.0 0.0016 17.7 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF3827 PF12877.7 KUM57038.1 - 0.92 7.8 5.5 1.3 7.3 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Moulting_cycle PF04870.16 KUM57038.1 - 0.95 8.7 5.0 0.34 10.1 2.5 1.5 1 1 0 1 1 1 0 Moulting cycle Pox_Ag35 PF03286.14 KUM57038.1 - 4.7 6.9 11.9 9.2 6.0 11.9 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PNP_UDP_1 PF01048.20 KUM57039.1 - 1e-05 25.0 0.1 1.5e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2813 PF11398.8 KUM57039.1 - 0.11 11.7 0.0 1.2 8.3 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2813) Hydrolase PF00702.26 KUM57040.1 - 4.4e-07 30.4 0.1 0.001 19.4 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KUM57040.1 - 0.0063 16.6 0.0 0.1 12.7 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KUM57040.1 - 0.036 14.5 0.1 0.24 11.8 0.1 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KUM57040.1 - 0.055 13.6 0.0 0.14 12.3 0.0 1.6 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KUM57040.1 - 0.17 11.5 0.0 0.43 10.2 0.0 1.6 1 1 0 1 1 1 0 Mitochondrial PGP phosphatase TRP PF06011.12 KUM57041.1 - 1.6e-166 554.3 18.7 2.1e-166 553.9 18.7 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KUM57041.1 - 2e-38 131.9 0.0 3.1e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Ac76 PF05814.11 KUM57041.1 - 0.82 9.7 8.8 7.6 6.6 0.1 3.4 3 0 0 3 3 3 0 Orf76 (Ac76) DUF1204 PF06721.11 KUM57042.1 - 7 6.0 9.4 0.24 10.8 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1204) Flavin_Reduct PF01613.18 KUM57044.1 - 2.2e-17 63.5 0.0 3e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF1829 PF08862.10 KUM57044.1 - 0.087 13.3 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF1829 Acetyltransf_3 PF13302.7 KUM57046.1 - 9e-13 49.1 0.0 1.2e-12 48.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM57046.1 - 6e-09 36.1 0.0 1.4e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KUM57046.1 - 0.0019 18.6 0.0 0.003 17.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KUM57046.1 - 0.01 15.5 0.0 0.04 13.6 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KUM57046.1 - 0.055 13.4 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CBM_21 PF03370.13 KUM57047.1 - 3e-36 124.0 0.2 4.9e-36 123.3 0.2 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KUM57047.1 - 1.2e-09 38.6 1.2 2.4e-09 37.7 1.2 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CENP-T_C PF15511.6 KUM57048.1 - 4.4e-09 36.4 0.1 5.3e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KUM57048.1 - 1.9e-05 25.1 0.2 2.2e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KUM57048.1 - 5e-05 23.4 0.2 7.3e-05 22.9 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KUM57048.1 - 0.00012 22.3 0.1 0.00021 21.5 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KUM57048.1 - 0.00017 21.9 0.1 0.00023 21.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KUM57048.1 - 0.0038 17.3 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KUM57048.1 - 0.0045 17.0 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 KUM57048.1 - 0.05 13.4 0.2 0.061 13.1 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TFIID_20kDa PF03847.13 KUM57048.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 KUM57048.1 - 0.073 13.1 0.0 0.082 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Fungal_trans_2 PF11951.8 KUM57049.1 - 4.3e-09 35.7 0.2 6.7e-09 35.0 0.0 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C3HC4 PF00097.25 KUM57050.1 - 1.9e-08 34.0 4.6 1.9e-08 34.0 4.6 4.5 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KUM57050.1 - 3.6e-08 33.3 4.2 3.6e-08 33.3 4.2 2.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.6 KUM57050.1 - 8.9e-07 28.7 0.9 8.9e-07 28.7 0.9 3.0 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 KUM57050.1 - 2.8e-06 27.6 6.1 2.8e-06 27.6 6.1 4.1 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.6 KUM57050.1 - 3.8e-06 26.6 6.5 3.8e-06 26.6 6.5 4.0 4 3 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KUM57050.1 - 1.2e-05 25.2 4.5 1.2e-05 25.2 4.5 5.4 5 0 0 5 5 5 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KUM57050.1 - 2.6e-05 24.3 6.2 2.6e-05 24.3 6.2 4.0 5 1 0 5 5 5 1 zinc finger of C3HC4-type, RING SH3_9 PF14604.6 KUM57050.1 - 0.00012 21.9 0.1 0.00012 21.9 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KUM57050.1 - 0.0015 18.1 0.1 0.0035 16.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KUM57050.1 - 0.0074 15.9 0.4 0.017 14.8 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain MIP PF00230.20 KUM57053.1 - 1.2e-52 178.9 6.9 1.5e-52 178.5 6.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein FGGY_C PF02782.16 KUM57054.1 - 3.1e-72 242.5 0.3 5.7e-72 241.6 0.3 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KUM57054.1 - 3.7e-67 226.4 0.0 5.1e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KUM57054.1 - 0.031 13.8 0.1 2 7.8 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family p450 PF00067.22 KUM57055.1 - 6.6e-60 203.2 0.0 8.6e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-CCCH_2 PF14608.6 KUM57056.1 - 4.4e-12 46.0 59.4 0.0002 21.7 12.5 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 KUM57056.1 - 0.0016 18.7 0.0 0.0026 18.0 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Peptidase_C58 PF03543.14 KUM57056.1 - 0.11 12.2 0.4 0.81 9.4 0.1 2.1 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen Mago-bind PF09282.10 KUM57058.1 - 1.4e-14 53.6 4.3 2.6e-14 52.8 4.3 1.5 1 0 0 1 1 1 1 Mago binding Med3 PF11593.8 KUM57058.1 - 0.094 11.9 6.9 0.13 11.4 6.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Raftlin PF15250.6 KUM57058.1 - 1.7 7.3 5.9 2 7.1 5.9 1.1 1 0 0 1 1 1 0 Raftlin Amino_oxidase PF01593.24 KUM57059.1 - 9.4e-32 110.9 0.0 1.2e-31 110.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KUM57059.1 - 1.2e-14 54.3 0.5 3.4e-13 49.6 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM57059.1 - 4.4e-06 26.5 0.0 2.3e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KUM57059.1 - 0.032 13.6 0.1 0.06 12.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KUM57059.1 - 0.13 12.2 0.0 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding zf-UBR PF02207.20 KUM57060.1 - 6.7e-19 67.8 15.0 1.9e-18 66.4 15.0 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KUM57060.1 - 0.00089 19.0 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_5 PF14634.6 KUM57060.1 - 0.0041 17.0 1.3 0.0041 17.0 1.3 3.9 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 KUM57060.1 - 0.0046 17.3 1.4 0.0046 17.3 1.4 4.4 4 1 1 5 5 5 1 Ring finger domain Nop14 PF04147.12 KUM57060.1 - 0.74 8.0 5.4 1.2 7.3 5.4 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KUM57060.1 - 2.6 6.0 11.2 5 5.1 11.2 1.4 1 0 0 1 1 1 0 DNA polymerase phi UCR_UQCRX_QCR9 PF05365.12 KUM57061.1 - 1.1e-25 89.4 2.9 1.2e-25 89.2 2.9 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4203 PF13886.6 KUM57061.1 - 0.02 14.6 0.0 0.02 14.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Glyco_hydro_16 PF00722.21 KUM57063.1 - 6.2e-36 123.5 6.3 1e-35 122.8 6.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF347 PF03988.12 KUM57063.1 - 0.045 13.9 0.1 0.097 12.9 0.1 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Bromo_TP PF07524.13 KUM57064.1 - 1.2e-06 28.4 0.0 2.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 KUM57064.1 - 0.025 14.6 0.0 0.041 13.9 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Glyco_hydro_16 PF00722.21 KUM57066.1 - 3.9e-35 120.9 4.7 9.9e-23 80.5 2.4 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 NDUFB10 PF10249.9 KUM57069.1 - 0.0074 16.8 0.0 0.0086 16.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 BRO1 PF03097.18 KUM57070.1 - 2.4e-09 36.5 0.0 4.1e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain Pkinase PF00069.25 KUM57071.1 - 5.5e-68 229.2 0.0 1.1e-67 228.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM57071.1 - 5.4e-34 117.7 0.0 9e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KUM57071.1 - 1.1e-10 41.7 0.5 4.9e-10 39.6 0.5 2.0 2 0 0 2 2 2 1 FHA domain APH PF01636.23 KUM57071.1 - 2e-05 24.6 0.9 0.021 14.7 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Yop-YscD_cpl PF16697.5 KUM57071.1 - 0.00084 19.6 0.0 0.0025 18.1 0.0 1.7 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KUM57071.1 - 0.0012 18.3 0.2 0.0023 17.3 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KUM57071.1 - 0.076 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KUM57071.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Glyco_transf_34 PF05637.12 KUM57072.1 - 1.4e-63 214.8 0.4 1.9e-63 214.4 0.4 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Beta_elim_lyase PF01212.21 KUM57073.1 - 8.4e-69 232.1 0.0 1e-68 231.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 KUM57073.1 - 0.0014 17.5 0.1 0.0026 16.5 0.1 1.4 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 KUM57073.1 - 0.0015 17.2 0.0 0.0023 16.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KUM57073.1 - 0.11 11.4 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DUF2703 PF10865.8 KUM57074.1 - 0.015 15.4 0.4 0.72 10.0 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2703) SlyX PF04102.12 KUM57074.1 - 1.5 9.5 4.9 1.9 9.1 0.0 3.3 3 0 0 3 3 3 0 SlyX DUF4407 PF14362.6 KUM57074.1 - 3.6 6.8 8.4 9.6 5.5 6.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Peptidase_M50B PF13398.6 KUM57075.1 - 2.3e-60 203.7 23.4 2.8e-60 203.4 23.4 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 KUM57075.1 - 0.0074 15.6 0.6 0.015 14.6 0.2 1.6 2 0 0 2 2 2 1 Peptidase family M50 Peptidase_M41 PF01434.18 KUM57075.1 - 0.21 11.4 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M41 Patched PF02460.18 KUM57075.1 - 1.5 6.8 6.6 2.7 5.9 6.6 1.3 1 0 0 1 1 1 0 Patched family Metallophos PF00149.28 KUM57076.1 - 5.1e-38 131.6 0.4 8.4e-38 130.9 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KUM57076.1 - 0.025 15.0 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain UvdE PF03851.14 KUM57078.1 - 1.5e-112 375.4 0.0 2e-112 374.9 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF2183 PF09949.9 KUM57079.1 - 5.1e-33 113.4 0.0 1.2e-32 112.1 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.6 KUM57079.1 - 0.043 14.1 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain LNS2 PF08235.13 KUM57079.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Acyl-CoA_dh_1 PF00441.24 KUM57080.1 - 2e-29 102.7 2.2 3.9e-29 101.8 2.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KUM57080.1 - 1.7e-20 72.9 0.0 3.7e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KUM57080.1 - 1.4e-19 70.1 0.2 2.9e-19 69.1 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KUM57080.1 - 1.1e-07 32.5 0.1 3.2e-07 31.0 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KUM57080.1 - 0.0024 18.1 0.0 0.0059 16.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2153 PF09921.9 KUM57080.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) PI31_Prot_N PF11566.8 KUM57081.1 - 5.7e-54 182.3 0.0 6.9e-54 182.0 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KUM57081.1 - 8.5e-18 65.3 16.2 8.5e-18 65.3 16.2 3.1 3 1 0 3 3 3 1 PI31 proteasome regulator Hexokinase_1 PF00349.21 KUM57082.1 - 8.3e-34 117.2 0.0 1e-33 117.0 0.0 1.1 1 0 0 1 1 1 1 Hexokinase MFS_1 PF07690.16 KUM57083.1 - 8.3e-22 77.6 73.1 2.1e-16 59.8 39.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_12 PF13424.6 KUM57085.1 - 3.2e-07 30.5 23.1 0.67 10.3 0.6 9.2 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 KUM57085.1 - 0.00022 21.0 4.5 6.2 7.1 0.2 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat NACHT PF05729.12 KUM57085.1 - 0.014 15.3 0.2 0.078 12.9 0.1 2.5 2 0 0 2 2 2 0 NACHT domain DRY_EERY PF09750.9 KUM57085.1 - 0.034 14.4 0.3 0.11 12.8 0.3 1.9 1 0 0 1 1 1 0 Alternative splicing regulator TPR_10 PF13374.6 KUM57085.1 - 0.046 13.6 14.2 21 5.1 0.0 8.2 8 0 0 8 8 8 0 Tetratricopeptide repeat CTP_transf_3 PF02348.19 KUM57085.1 - 2.3 8.1 7.2 0.24 11.3 0.1 2.8 3 0 0 3 3 3 0 Cytidylyltransferase E1_DerP2_DerF2 PF02221.15 KUM57087.1 - 6.4e-28 97.9 0.2 9e-28 97.4 0.2 1.1 1 0 0 1 1 1 1 ML domain DUF1091 PF06477.13 KUM57087.1 - 0.13 12.7 0.1 0.8 10.2 0.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1091) Catalase PF00199.19 KUM57087.1 - 0.2 10.7 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Catalase ATP-synt_F PF01990.17 KUM57088.1 - 1.3e-33 115.2 0.0 1.5e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.13 KUM57088.1 - 0.17 11.7 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 DUF2418 PF10332.9 KUM57089.1 - 2.5e-37 127.3 0.2 6.5e-37 126.0 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) MTHFR PF02219.17 KUM57091.1 - 3.1e-115 384.4 0.0 4.5e-115 383.9 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Pribosyltran PF00156.27 KUM57092.1 - 2.7e-14 53.0 0.4 4e-14 52.4 0.4 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Alpha-amylase PF00128.24 KUM57093.1 - 2.5e-16 60.2 1.5 2.5e-16 60.2 1.5 2.5 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KUM57093.1 - 7.5e-14 52.0 0.1 1.3e-13 51.3 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KUM57093.1 - 0.0004 20.0 0.0 0.00076 19.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KUM57093.1 - 0.058 13.4 0.5 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase Family 4 VirB8 PF04335.13 KUM57093.1 - 0.14 11.9 0.1 0.49 10.2 0.1 1.9 1 0 0 1 1 1 0 VirB8 protein Methyltransf_25 PF13649.6 KUM57094.1 - 4.7e-09 36.8 0.0 6e-08 33.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM57094.1 - 2e-07 31.0 0.0 5.7e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM57094.1 - 4.1e-07 30.7 0.0 1.8e-06 28.6 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM57094.1 - 9.5e-05 23.0 0.0 0.00026 21.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM57094.1 - 0.00053 19.8 0.0 0.00086 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KUM57094.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family FAD_binding_4 PF01565.23 KUM57095.1 - 5.3e-22 78.1 5.0 1.7e-21 76.5 5.0 1.9 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KUM57095.1 - 3.1e-11 43.2 0.4 6e-11 42.3 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cu_bind_like PF02298.17 KUM57096.1 - 0.011 15.7 0.3 0.04 13.9 0.3 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain VSP PF03302.13 KUM57097.1 - 0.00019 20.4 3.1 0.00026 20.0 3.1 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein EphA2_TM PF14575.6 KUM57097.1 - 0.032 15.1 0.0 0.041 14.8 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DDE_1 PF03184.19 KUM57098.1 - 1.8e-37 128.7 0.8 5.4e-37 127.1 0.1 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_ABP1_N PF18107.1 KUM57098.1 - 1.2e-26 92.2 0.2 1.2e-26 92.2 0.2 2.1 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 KUM57098.1 - 6.7e-13 48.5 1.1 3.2e-12 46.3 0.1 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_32 PF13565.6 KUM57098.1 - 0.059 14.0 0.3 0.38 11.4 0.1 2.5 3 0 0 3 3 3 0 Homeodomain-like domain ILVD_EDD PF00920.21 KUM57099.1 - 1.7e-207 690.2 0.3 2e-207 689.9 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.18 KUM57099.1 - 0.0039 17.4 0.0 0.016 15.5 0.0 2.0 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 KUM57100.1 - 1.3e-31 109.8 0.5 3.1e-31 108.6 0.5 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KUM57100.1 - 7e-19 68.6 0.2 1.7e-18 67.3 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KUM57100.1 - 1.3e-18 67.0 0.0 2.6e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KUM57100.1 - 3.8e-14 53.1 2.1 9e-14 51.9 0.3 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain p450 PF00067.22 KUM57102.1 - 1.5e-30 106.3 0.0 1.9e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.21 KUM57104.1 - 6e-39 134.0 0.0 7.2e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_6 PF12697.7 KUM57105.1 - 1.1e-20 75.3 0.9 1.3e-20 75.0 0.9 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM57105.1 - 8.8e-05 21.9 0.0 0.41 9.9 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KUM57105.1 - 0.0029 17.5 0.7 0.0061 16.4 0.4 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KUM57105.1 - 0.076 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 KUM57105.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein PAS_4 PF08448.10 KUM57105.1 - 0.17 12.1 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold Mito_carr PF00153.27 KUM57106.1 - 4.8e-31 106.5 4.5 8.5e-15 54.5 0.4 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein CbtA PF09490.10 KUM57106.1 - 0.15 11.8 3.1 0.21 11.3 3.1 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) AA_permease PF00324.21 KUM57107.1 - 3.8e-93 312.7 42.4 4.3e-93 312.5 42.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM57107.1 - 2e-22 79.7 44.7 2.5e-22 79.3 44.7 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_2_C PF02836.17 KUM57108.1 - 3.6e-92 308.7 0.1 4.8e-92 308.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KUM57108.1 - 1.1e-23 83.9 0.0 3.2e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KUM57108.1 - 3.9e-10 40.4 0.6 1.1e-09 38.9 0.6 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Cellulase PF00150.18 KUM57108.1 - 0.0032 16.9 0.7 0.047 13.1 0.6 2.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4434 PF14488.6 KUM57108.1 - 0.0064 16.5 0.0 0.019 15.0 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4434) Glyco_hydro_cc PF11790.8 KUM57108.1 - 0.063 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Big_5 PF13205.6 KUM57108.1 - 0.11 13.2 0.7 0.29 11.8 0.7 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain Mannosidase_ig PF17786.1 KUM57109.1 - 9.8e-20 71.0 1.0 1.3e-18 67.4 0.1 2.8 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KUM57109.1 - 1.1e-12 48.5 0.0 2.7e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KUM57109.1 - 0.0018 18.2 0.0 0.0054 16.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Aconitase PF00330.20 KUM57111.1 - 3.2e-111 372.6 0.3 2.6e-110 369.6 0.3 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KUM57111.1 - 2.5e-22 79.6 0.0 4.3e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Sugar_tr PF00083.24 KUM57112.1 - 2.1e-65 221.4 22.9 2.4e-65 221.2 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM57112.1 - 2.2e-29 102.5 48.7 6.5e-24 84.5 25.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM57112.1 - 6.2e-08 31.5 1.1 1.4e-07 30.4 1.1 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 KUM57113.1 - 1.1e-15 57.4 0.1 1.8e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMO-like PF00743.19 KUM57114.1 - 7.3e-18 64.3 0.5 2.5e-16 59.2 0.2 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KUM57114.1 - 1.2e-07 31.9 0.0 4.2e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KUM57114.1 - 0.00033 20.0 0.0 0.0033 16.7 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM57114.1 - 0.079 13.0 0.1 1.3 9.0 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding S_locus_glycop PF00954.20 KUM57114.1 - 0.097 13.2 3.5 0.89 10.1 0.3 2.4 2 0 0 2 2 2 0 S-locus glycoprotein domain Telomerase_RBD PF12009.8 KUM57115.1 - 3e-48 163.3 0.5 6.6e-48 162.2 0.5 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KUM57115.1 - 2.5e-13 50.1 0.0 1.1e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Imm63 PF15599.6 KUM57115.1 - 0.028 14.8 0.1 0.096 13.1 0.1 1.8 2 0 0 2 2 2 0 Immunity protein 63 RhoGEF PF00621.20 KUM57116.1 - 1.2e-35 123.4 0.0 2.5e-35 122.4 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain adh_short PF00106.25 KUM57117.1 - 4e-41 140.6 0.1 1.1e-40 139.2 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM57117.1 - 6.7e-40 137.1 0.1 2.2e-39 135.4 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM57117.1 - 1.2e-09 38.4 0.3 2.2e-09 37.5 0.0 1.6 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 KUM57117.1 - 0.00077 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KUM57117.1 - 0.0018 17.5 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 KUM57117.1 - 0.0041 17.1 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 KUM57117.1 - 0.0069 15.8 0.2 0.025 14.0 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Cation_ATPase_C PF00689.21 KUM57118.1 - 3.8e-43 147.3 3.6 3.8e-43 147.3 3.6 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KUM57118.1 - 1.2e-38 132.4 2.5 1.2e-38 132.4 2.5 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KUM57118.1 - 6.8e-23 82.1 0.0 1e-08 35.7 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KUM57118.1 - 5.1e-21 74.6 0.0 1.2e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KUM57118.1 - 1.2e-09 37.7 0.0 3.9e-09 36.1 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KUM57118.1 - 2.1e-05 24.4 0.1 8.4e-05 22.4 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KUM57118.1 - 0.012 16.0 0.0 0.94 9.9 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2207 PF09972.9 KUM57118.1 - 2.3 6.9 8.4 3.2 6.4 0.2 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) FtsK_4TM PF13491.6 KUM57118.1 - 3 7.5 10.3 0.6 9.8 1.3 3.0 3 0 0 3 3 3 0 4TM region of DNA translocase FtsK/SpoIIIE Nucleos_tra2_N PF01773.20 KUM57118.1 - 3.7 8.2 7.9 5.1 7.8 0.1 3.6 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus Pkinase PF00069.25 KUM57119.1 - 3.8e-23 82.2 0.0 4e-20 72.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KUM57119.1 - 4.1e-16 59.1 0.0 7.2e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM57119.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RabGAP-TBC PF00566.18 KUM57120.1 - 3.1e-29 102.2 0.0 6.4e-29 101.2 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KUM57120.1 - 3.8e-08 32.1 1.6 3.8e-08 32.1 1.6 1.5 2 0 0 2 2 2 1 SBE2, cell-wall formation Thioredox_DsbH PF03190.15 KUM57122.1 - 1.7e-72 242.7 0.1 2.6e-72 242.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KUM57122.1 - 6.5e-07 29.4 0.0 1.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_9 PF00759.19 KUM57122.1 - 0.0012 18.4 0.1 0.0024 17.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_88 PF07470.13 KUM57122.1 - 0.04 13.0 0.1 18 4.3 0.0 3.2 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 KUM57122.1 - 0.069 12.6 1.2 6.8 6.1 0.0 2.7 3 0 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus Carn_acyltransf PF00755.20 KUM57123.1 - 2e-208 693.8 0.0 5.3e-208 692.4 0.0 1.6 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ligase_CoA PF00549.19 KUM57123.1 - 1.8e-34 118.8 0.5 3.1e-16 59.6 0.2 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 KUM57123.1 - 4.7e-18 65.7 0.2 1.1e-17 64.5 0.2 1.6 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 KUM57123.1 - 2.9e-10 40.1 0.0 1.5e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KUM57123.1 - 0.0081 16.6 0.1 0.03 14.8 0.1 2.0 1 0 0 1 1 1 1 CoA binding domain CAP PF00188.26 KUM57124.1 - 2.2e-16 60.9 1.3 4.9e-16 59.7 1.3 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RAP1 PF07218.11 KUM57124.1 - 3.8 5.7 6.9 4.8 5.3 6.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SWI-SNF_Ssr4 PF08549.10 KUM57124.1 - 7.1 5.1 8.7 9 4.8 8.7 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Velvet PF11754.8 KUM57125.1 - 5.2e-14 52.8 0.0 5.2e-14 52.8 0.0 2.2 2 1 0 2 2 2 1 Velvet factor Med9 PF07544.13 KUM57126.1 - 0.098 12.8 0.7 0.3 11.2 0.7 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 MFS_1 PF07690.16 KUM57127.1 - 1.1e-19 70.6 56.1 1.9e-12 46.8 29.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LSM14 PF12701.7 KUM57128.1 - 1.6e-27 95.4 0.0 2.5e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KUM57128.1 - 2.3e-20 73.4 2.7 4.8e-20 72.4 2.7 1.5 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.6 KUM57128.1 - 4.4e-06 26.8 0.0 7.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain TFIIA PF03153.13 KUM57128.1 - 0.47 10.4 18.5 0.75 9.7 18.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 KUM57129.1 - 2.8e-22 78.6 5.9 6.8e-05 23.6 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM57129.1 - 4.6e-06 26.8 0.0 0.049 13.9 0.0 4.1 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Reg_prop PF07494.11 KUM57129.1 - 0.0016 18.4 0.0 0.62 10.5 0.0 3.0 2 0 0 2 2 2 1 Two component regulator propeller Nup160 PF11715.8 KUM57129.1 - 0.014 14.1 0.2 0.33 9.5 0.1 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 BRK PF07533.16 KUM57129.1 - 0.027 14.1 0.2 32 4.2 0.0 3.8 3 0 0 3 3 3 0 BRK domain PQQ_3 PF13570.6 KUM57129.1 - 0.18 12.3 2.9 10 6.7 0.0 4.4 4 1 1 5 5 5 0 PQQ-like domain ADH_zinc_N PF00107.26 KUM57130.1 - 1.1e-17 64.2 0.0 1.8e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM57130.1 - 1.3e-13 50.7 0.2 2.7e-13 49.8 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KUM57130.1 - 2.4e-07 31.9 0.0 5.1e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KUM57130.1 - 0.00079 18.8 0.1 0.0013 18.1 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KUM57130.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 KUM57131.1 - 1.3e-30 106.3 0.0 1.9e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM57131.1 - 1.7e-25 90.0 0.0 2.3e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM57131.1 - 7.8e-10 38.9 0.0 8.3e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KUM57131.1 - 0.0058 16.1 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Aa_trans PF01490.18 KUM57132.1 - 2e-27 96.0 34.7 2.5e-27 95.6 34.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 KUM57132.1 - 4.8e-10 38.8 42.5 1.7e-08 33.8 42.4 2.1 1 1 0 1 1 1 1 Amino acid permease Tmemb_55A PF09788.9 KUM57132.1 - 0.15 11.1 0.4 0.42 9.6 0.4 1.7 1 0 0 1 1 1 0 Transmembrane protein 55A TauD PF02668.16 KUM57133.1 - 4.6e-52 177.4 0.1 5.6e-52 177.2 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family OPT PF03169.15 KUM57134.1 - 4.7e-119 398.8 33.0 5.3e-119 398.6 33.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ribonuc_P_40 PF08584.11 KUM57134.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Tetraspanin PF00335.20 KUM57134.1 - 1.7 8.3 5.9 0.23 11.1 0.4 2.3 2 0 0 2 2 2 0 Tetraspanin family Lactamase_B PF00753.27 KUM57135.1 - 1.5e-09 38.2 0.1 2.5e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KUM57135.1 - 0.039 13.5 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain HNHc_6 PF16784.5 KUM57135.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative HNHc nuclease MFS_1 PF07690.16 KUM57136.1 - 3.6e-32 111.7 39.1 3.6e-32 111.7 39.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OSTbeta PF15048.6 KUM57136.1 - 0.033 14.3 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF1129 PF06570.11 KUM57136.1 - 0.089 12.3 2.8 0.87 9.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Baculo_11_kDa PF06143.11 KUM57136.1 - 8 6.1 7.0 2.4 7.8 0.0 2.9 3 0 0 3 3 3 0 Baculovirus 11 kDa family FMO-like PF00743.19 KUM57137.1 - 6.3e-18 64.5 0.0 9.7e-17 60.6 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KUM57137.1 - 4.5e-09 36.4 0.0 1.2e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM57137.1 - 4e-07 29.6 0.0 0.00041 19.7 0.0 2.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM57137.1 - 4.4e-06 26.2 0.0 0.00016 21.1 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM57137.1 - 2.4e-05 23.6 0.0 0.00069 18.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KUM57137.1 - 0.0018 18.3 0.2 0.17 11.9 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KUM57137.1 - 0.054 12.7 0.0 9.3 5.4 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Abhydrolase_3 PF07859.13 KUM57138.1 - 5.2e-51 173.5 0.0 7e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KUM57138.1 - 8.6e-14 51.3 0.9 3.5e-13 49.3 0.2 2.2 2 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KUM57138.1 - 8.6e-05 23.2 0.0 0.00011 22.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Patatin PF01734.22 KUM57138.1 - 0.13 12.4 0.1 0.31 11.2 0.1 1.6 1 0 0 1 1 1 0 Patatin-like phospholipase Snf7 PF03357.21 KUM57139.1 - 1.2e-21 77.0 6.8 1.2e-21 77.0 6.8 1.7 2 0 0 2 2 2 1 Snf7 Gon7 PF08738.10 KUM57139.1 - 0.013 15.6 6.4 0.037 14.1 3.7 2.3 2 1 0 2 2 2 0 Gon7 family TPR_MLP1_2 PF07926.12 KUM57139.1 - 0.02 14.9 4.1 0.02 14.9 4.1 3.1 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein PSD4 PF07631.11 KUM57139.1 - 0.024 15.2 1.4 0.075 13.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1592) BMFP PF04380.13 KUM57139.1 - 0.037 14.5 8.4 0.65 10.5 1.5 3.8 3 1 0 3 3 3 0 Membrane fusogenic activity Fez1 PF06818.15 KUM57139.1 - 4.2 7.8 11.4 83 3.5 11.4 2.0 1 1 0 1 1 1 0 Fez1 Fib_alpha PF08702.10 KUM57139.1 - 5.8 7.1 9.4 4 7.6 4.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DFRP_C PF16543.5 KUM57140.1 - 7.8e-23 80.8 7.9 7.8e-23 80.8 7.9 3.8 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 KUM57140.1 - 0.00011 22.8 5.1 0.00011 22.8 5.1 3.6 2 2 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 KUM57140.1 - 0.00014 21.7 3.1 0.00014 21.7 3.1 2.6 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KUM57140.1 - 0.00083 19.1 11.0 0.0025 17.6 3.0 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KUM57140.1 - 0.013 15.5 7.5 0.013 15.5 7.5 3.1 4 0 0 4 4 4 0 Zinc finger domain zf-CCCH_3 PF15663.5 KUM57140.1 - 1.7 8.9 9.3 0.42 10.8 0.2 3.0 4 0 0 4 4 4 0 Zinc-finger containing family DAO PF01266.24 KUM57142.1 - 9.4e-30 104.4 0.1 1.1e-29 104.1 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM57142.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF267 PF03268.14 KUM57142.1 - 0.27 10.1 0.0 0.37 9.6 0.0 1.1 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 RRM_7 PF16367.5 KUM57143.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif CS PF04969.16 KUM57144.1 - 9.2e-07 29.8 0.0 1.5e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 CS domain LysM PF01476.20 KUM57145.1 - 1.6e-06 28.1 0.0 0.14 12.3 0.0 3.3 3 0 0 3 3 3 3 LysM domain 2-Hacid_dh_C PF02826.19 KUM57146.1 - 1.3e-37 128.8 0.0 2.2e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KUM57146.1 - 2e-20 72.8 0.0 2.6e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 KUM57146.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 KUM57146.1 - 0.022 14.8 2.4 0.032 14.3 0.5 2.2 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 KUM57146.1 - 0.089 13.3 0.0 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain EF-hand_8 PF13833.6 KUM57147.1 - 0.009 15.8 0.0 0.28 11.0 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KUM57147.1 - 0.017 15.0 0.1 0.98 9.5 0.0 3.3 4 0 0 4 4 4 0 EF-hand domain EF-hand_9 PF14658.6 KUM57147.1 - 0.066 13.5 0.0 10 6.5 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain FoP_duplication PF13865.6 KUM57148.1 - 1.4e-06 28.8 1.9 2.6e-06 27.9 1.9 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 KUM57148.1 - 1.5e-05 24.8 0.2 2.7e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PhzC-PhzF PF02567.16 KUM57149.1 - 3.9e-43 147.9 0.0 1.2e-28 100.4 0.0 2.0 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein PUL PF08324.11 KUM57150.1 - 2.7e-66 223.6 0.2 3.8e-66 223.2 0.2 1.1 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 KUM57150.1 - 2.1e-33 115.3 0.0 4.1e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 KUM57150.1 - 4.5e-15 55.5 0.0 8.8e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KUM57150.1 - 9.9e-05 22.8 0.4 0.003 18.0 0.4 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 KUM57150.1 - 0.00017 21.5 0.0 0.00027 20.8 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 KUM57150.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.6 KUM57150.1 - 0.0082 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin domain OST3_OST6 PF04756.13 KUM57150.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Redoxin PF08534.10 KUM57150.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Redoxin DUF202 PF02656.15 KUM57151.1 - 8.9 6.8 11.1 5.4e+02 1.1 9.8 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Macro PF01661.21 KUM57152.1 - 1.1e-09 38.3 0.0 1.3e-08 34.8 0.0 2.1 1 1 0 1 1 1 1 Macro domain Ribonuclease_T2 PF00445.18 KUM57153.1 - 2e-45 155.3 1.2 3.2e-45 154.6 1.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family SBDS_C PF09377.10 KUM57153.1 - 0.035 14.1 0.0 0.77 9.8 0.0 2.2 2 0 0 2 2 2 0 SBDS protein C-terminal domain Lipoprotein_16 PF03923.13 KUM57154.1 - 0.011 15.5 0.5 0.016 14.8 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized lipoprotein MFS_1 PF07690.16 KUM57155.1 - 7.3e-37 127.1 37.8 4.8e-31 108.0 13.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KUM57155.1 - 2.8e-06 25.9 0.3 2.8e-06 25.9 0.3 1.7 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF334 PF03904.13 KUM57155.1 - 0.066 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF334) BCNT PF07572.12 KUM57156.1 - 4.7e-25 87.5 1.1 1.5e-24 85.8 1.1 1.9 1 0 0 1 1 1 1 Bucentaur or craniofacial development TFIIF_alpha PF05793.12 KUM57156.1 - 0.00024 19.9 22.1 0.00037 19.2 22.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-X PF09415.10 KUM57159.1 - 2.2e-28 98.4 0.7 3.3e-28 97.8 0.0 1.7 2 0 0 2 2 2 1 CENP-S associating Centromere protein X DUF2934 PF11154.8 KUM57159.1 - 0.0031 17.2 0.4 0.0053 16.4 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2934) CBFD_NFYB_HMF PF00808.23 KUM57159.1 - 0.006 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PIEZO PF15917.5 KUM57159.1 - 0.25 10.8 4.5 0.34 10.4 4.5 1.2 1 0 0 1 1 1 0 Piezo Apt1 PF10351.9 KUM57159.1 - 0.37 9.6 9.2 0.43 9.4 9.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SMYLE_N PF18615.1 KUM57159.1 - 0.61 9.6 6.4 0.69 9.4 6.4 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain RGS12_us2 PF16611.5 KUM57159.1 - 1.5 9.3 11.8 0.57 10.6 8.7 1.9 2 0 0 2 2 1 0 Unstructured region between RBD and GoLoco Neur_chan_memb PF02932.16 KUM57159.1 - 1.6 8.8 5.1 2.2 8.3 5.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 KUM57159.1 - 3 6.5 7.6 3.4 6.3 7.6 1.2 1 0 0 1 1 1 0 Presenilin SPX PF03105.19 KUM57159.1 - 4.3 7.2 18.6 5.3 6.8 18.6 1.1 1 0 0 1 1 1 0 SPX domain DUF4551 PF15087.6 KUM57159.1 - 4.5 6.0 11.4 5.5 5.7 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MAP65_ASE1 PF03999.12 KUM57159.1 - 5.3 5.6 16.4 6.2 5.4 16.4 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) MIF PF01187.18 KUM57160.1 - 6.4e-06 26.4 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Amidohydro_1 PF01979.20 KUM57161.1 - 5.1e-07 29.3 0.0 8.5e-07 28.6 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 KUM57161.1 - 0.00014 21.7 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Mis12 PF05859.12 KUM57162.1 - 4.9e-47 159.4 0.0 9e-47 158.5 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein p450 PF00067.22 KUM57164.1 - 9.1e-104 347.8 0.0 1e-103 347.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OPT PF03169.15 KUM57165.1 - 1.9e-180 601.6 57.6 2.1e-180 601.4 57.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein LSM PF01423.22 KUM57166.1 - 3.9e-17 61.7 0.6 5e-17 61.4 0.6 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KUM57166.1 - 0.013 15.6 0.0 0.017 15.2 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain Hfq PF17209.3 KUM57166.1 - 0.019 14.6 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 Hfq protein LRR_9 PF14580.6 KUM57166.1 - 0.04 13.4 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeat NTP_transf_2 PF01909.23 KUM57166.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 1 0 1 1 1 0 Nucleotidyltransferase domain Abhydrolase_6 PF12697.7 KUM57167.1 - 7.4e-10 39.8 0.0 1.2e-09 39.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM57167.1 - 2.1e-07 30.9 0.1 3.1e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM57167.1 - 9.4e-06 25.1 0.1 1.6e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIP PF03583.14 KUM57167.1 - 0.039 13.3 0.2 0.081 12.2 0.2 1.4 1 0 0 1 1 1 0 Secretory lipase DRMBL PF07522.14 KUM57168.1 - 1.9e-34 118.2 0.0 3.4e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KUM57168.1 - 0.00022 20.8 0.0 0.00042 19.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Methyltransf_11 PF08241.12 KUM57169.1 - 8.7e-09 35.9 0.0 1.7e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM57169.1 - 0.00021 22.0 0.0 0.00052 20.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM57169.1 - 0.031 14.1 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 KUM57170.1 - 7.6e-08 32.4 10.8 7.6e-08 32.4 10.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNase_T PF00929.24 KUM57171.1 - 6.3e-12 46.3 0.0 9.5e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KUM57171.1 - 0.0009 19.3 0.1 0.0021 18.1 0.1 1.6 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like DNA_pol_A_exo1 PF01612.20 KUM57171.1 - 0.028 14.2 0.0 0.095 12.4 0.0 2.0 1 1 0 1 1 1 0 3'-5' exonuclease Glyco_hydro_43 PF04616.14 KUM57172.1 - 5e-72 242.6 0.6 7.7e-72 242.0 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KUM57172.1 - 6.3e-11 42.4 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Sugar_tr PF00083.24 KUM57173.1 - 1.2e-72 245.2 22.7 1.5e-72 245.0 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM57173.1 - 6.6e-23 81.2 31.2 5.6e-16 58.4 11.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM57173.1 - 0.00079 18.0 4.1 0.00079 18.0 4.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ketoacyl-synt PF00109.26 KUM57175.1 - 1.2e-74 251.1 0.7 1.8e-74 250.5 0.1 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KUM57175.1 - 1.9e-58 197.3 0.0 4.2e-58 196.2 0.0 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KUM57175.1 - 1.2e-48 166.2 0.1 2.3e-48 165.3 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KUM57175.1 - 5e-48 163.8 0.0 8.3e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KUM57175.1 - 1.5e-36 125.0 0.0 3.6e-36 123.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KUM57175.1 - 6.6e-21 74.9 0.0 2e-20 73.3 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KUM57175.1 - 1.8e-11 43.9 0.0 4.2e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 KUM57175.1 - 2.1e-06 28.0 1.1 6.7e-06 26.4 0.1 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KUM57175.1 - 9.2e-06 25.4 0.0 2.7e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KUM57175.1 - 0.00015 21.2 0.1 0.0003 20.2 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain SAT PF16073.5 KUM57175.1 - 0.0024 17.7 1.3 0.023 14.4 0.0 3.0 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 KUM57175.1 - 0.0036 17.1 0.3 0.023 14.5 0.1 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.12 KUM57175.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain NapD PF03927.13 KUM57175.1 - 0.18 11.9 0.0 0.86 9.7 0.0 2.2 1 0 0 1 1 1 0 NapD protein ADH_zinc_N PF00107.26 KUM57176.1 - 1.5e-09 38.0 0.0 2.9e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM57176.1 - 3e-05 23.9 0.1 9.1e-05 22.3 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KUM57176.1 - 0.052 14.6 0.0 0.74 10.9 0.1 2.4 2 1 0 2 2 2 0 Zinc-binding dehydrogenase MASE3 PF17159.4 KUM57178.1 - 0.0064 16.1 6.6 0.0064 16.1 6.6 1.7 2 0 0 2 2 2 1 Membrane-associated sensor domain DUF2417 PF10329.9 KUM57178.1 - 0.047 13.1 2.5 0.3 10.5 1.5 2.3 2 0 0 2 2 2 0 Region of unknown function (DUF2417) DUF2162 PF09930.9 KUM57178.1 - 0.15 11.5 6.9 0.56 9.6 6.9 1.9 1 1 0 1 1 1 0 Predicted transporter (DUF2162) AgrB PF04647.15 KUM57178.1 - 0.91 8.8 6.0 0.18 11.1 2.2 1.7 2 0 0 2 2 2 0 Accessory gene regulator B YfhO PF09586.10 KUM57178.1 - 1 7.5 4.3 1.5 7.0 4.3 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF1129 PF06570.11 KUM57178.1 - 3.6 7.0 4.6 7.9 5.9 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) QueT PF06177.11 KUM57178.1 - 7.5 6.9 13.9 0.049 14.0 1.8 2.8 3 0 0 3 3 3 0 QueT transporter DUF805 PF05656.14 KUM57178.1 - 9.3 6.7 14.1 0.92 9.9 5.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF805) Mpv17_PMP22 PF04117.12 KUM57179.1 - 1.2e-22 79.8 2.2 1.2e-22 79.8 2.2 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family IF4E PF01652.18 KUM57180.1 - 3.3e-53 179.7 0.5 4.3e-53 179.4 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ribosomal_S5 PF00333.20 KUM57182.1 - 2.9e-25 88.0 1.1 8e-25 86.6 0.5 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KUM57182.1 - 3.7e-23 80.8 0.0 6.5e-23 80.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 KUM57182.1 - 0.47 11.0 11.7 1 9.9 11.7 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 PTR2 PF00854.21 KUM57184.1 - 1.3e-89 300.8 9.8 2e-89 300.2 9.8 1.2 1 0 0 1 1 1 1 POT family BolA PF01722.18 KUM57185.1 - 3.2e-30 104.2 3.2 4.2e-30 103.8 3.2 1.2 1 0 0 1 1 1 1 BolA-like protein SNARE PF05739.19 KUM57186.1 - 9.9e-13 47.9 0.4 9.9e-13 47.9 0.4 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 KUM57186.1 - 2e-11 44.0 12.7 2e-11 44.0 12.7 1.6 2 0 0 2 2 2 1 Syntaxin Use1 PF09753.9 KUM57186.1 - 0.0026 17.5 10.5 0.0037 17.0 10.5 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 T7SS_ESX_EspC PF10824.8 KUM57186.1 - 0.0065 16.9 7.4 9.3 6.8 0.0 4.1 2 1 1 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm VitD-bind_III PF09164.10 KUM57186.1 - 0.013 15.5 0.1 0.062 13.3 0.1 2.1 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Syntaxin_2 PF14523.6 KUM57186.1 - 0.017 15.5 5.4 0.017 15.5 5.4 3.0 2 2 0 2 2 2 0 Syntaxin-like protein Spore_III_AB PF09548.10 KUM57186.1 - 0.039 14.1 0.2 0.039 14.1 0.2 2.4 2 2 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) COG5 PF10392.9 KUM57186.1 - 0.04 14.1 9.5 0.055 13.6 0.3 3.3 3 1 0 3 3 3 0 Golgi transport complex subunit 5 CD225 PF04505.12 KUM57186.1 - 0.044 13.9 0.9 0.091 12.9 0.9 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein NPV_P10 PF05531.12 KUM57186.1 - 0.07 13.6 5.2 1.2 9.6 0.0 3.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ETRAMP PF09716.10 KUM57186.1 - 0.09 12.8 0.7 0.17 11.9 0.7 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF2207 PF09972.9 KUM57186.1 - 0.092 11.5 0.1 0.092 11.5 0.1 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) PBP1_TM PF14812.6 KUM57186.1 - 0.17 12.3 2.0 0.59 10.5 0.0 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fib_alpha PF08702.10 KUM57186.1 - 0.27 11.4 14.1 1.2 9.4 1.3 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.11 KUM57186.1 - 0.67 10.5 12.4 0.7 10.5 0.9 3.5 1 1 3 4 4 4 0 Syntaxin 6, N-terminal Tweety PF04906.13 KUM57186.1 - 0.74 8.4 7.0 0.21 10.2 2.5 2.0 1 1 1 2 2 2 0 Tweety LXG PF04740.12 KUM57186.1 - 1.1 8.9 13.3 0.66 9.7 4.0 2.3 2 0 0 2 2 2 0 LXG domain of WXG superfamily TetR_C_15 PF17918.1 KUM57186.1 - 1.4 9.7 4.7 23 5.8 0.8 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain LMBR1 PF04791.16 KUM57186.1 - 2.4 7.0 12.6 4.5 6.1 12.6 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF5082 PF16888.5 KUM57186.1 - 3.3 8.0 17.1 8.9 6.6 6.0 3.6 2 2 0 2 2 2 0 Domain of unknown function (DUF5082) MCU PF04678.13 KUM57186.1 - 3.3 7.8 10.8 1.4e+02 2.5 10.9 2.5 1 1 0 1 1 1 0 Mitochondrial calcium uniporter HisKA_3 PF07730.13 KUM57186.1 - 4.3 7.9 10.1 2 9.0 0.1 3.7 2 2 2 4 4 4 0 Histidine kinase Laminin_II PF06009.12 KUM57186.1 - 4.7 7.2 15.4 2.6 8.1 3.9 3.2 2 1 1 3 3 3 0 Laminin Domain II COG2 PF06148.11 KUM57186.1 - 6.1 6.9 9.8 3.1 7.9 0.3 3.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 YpzI PF14140.6 KUM57187.1 - 0.13 12.0 18.7 3 7.7 0.1 5.3 5 0 0 5 5 5 0 YpzI-like protein AMP-binding PF00501.28 KUM57188.1 - 3.7e-65 220.2 0.0 5.2e-65 219.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM57188.1 - 4.3e-13 50.0 0.1 1.7e-12 48.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Frag1 PF10277.9 KUM57189.1 - 6.3e-44 150.1 14.6 7.1e-44 149.9 14.6 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3382 PF11862.8 KUM57189.1 - 0.073 13.3 1.8 0.13 12.5 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) DUF962 PF06127.11 KUM57189.1 - 0.39 10.8 2.5 5.8 7.1 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF962) DUF4006 PF13179.6 KUM57189.1 - 0.61 10.0 0.1 0.61 10.0 0.1 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF4006) DUF3087 PF11286.8 KUM57189.1 - 1.4 8.3 6.0 0.29 10.6 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3087) Na_Ca_ex PF01699.24 KUM57189.1 - 3.2 7.7 15.2 1.4 8.8 9.0 2.7 1 1 1 2 2 2 0 Sodium/calcium exchanger protein Presenilin PF01080.17 KUM57191.1 - 0.078 11.7 0.4 0.096 11.4 0.4 1.0 1 0 0 1 1 1 0 Presenilin Glyco_hydro_18 PF00704.28 KUM57192.1 - 1.2e-64 219.1 7.4 1.2e-64 219.1 7.4 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KUM57192.1 - 1.5e-11 44.5 18.0 1.5e-11 44.5 18.0 4.0 4 0 0 4 4 4 1 Chitin recognition protein DNase_NucA_NucB PF14040.6 KUM57192.1 - 5.4e-06 26.8 0.1 5.4e-06 26.8 0.1 2.9 4 0 0 4 4 4 1 Deoxyribonuclease NucA/NucB LysM PF01476.20 KUM57193.1 - 9.6e-16 57.6 1.7 1.7e-07 31.2 0.0 4.3 4 0 0 4 4 4 3 LysM domain Chitin_bind_1 PF00187.19 KUM57193.1 - 0.00034 21.0 20.2 0.00034 21.0 20.2 3.8 5 0 0 5 5 5 1 Chitin recognition protein Myb_DNA-bind_6 PF13921.6 KUM57195.1 - 7e-05 23.0 0.0 8.1e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3836 PF12930.7 KUM57195.1 - 0.074 12.8 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF3836) Myb_DNA-binding PF00249.31 KUM57195.1 - 0.1 12.8 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain BRD4_CDT PF17105.5 KUM57197.1 - 0.097 12.3 2.0 0.14 11.7 2.0 1.2 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 DUF3915 PF13054.6 KUM57197.1 - 0.82 9.7 3.9 1.1 9.2 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Ysc84 PF04366.12 KUM57198.1 - 1.3e-39 134.8 0.4 2.7e-39 133.8 0.4 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KUM57198.1 - 2.1e-13 49.6 0.2 7e-13 48.0 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KUM57198.1 - 7.9e-12 44.7 0.2 2e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KUM57198.1 - 6.4e-10 38.7 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CUE PF02845.16 KUM57199.1 - 0.05 13.3 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 CUE domain Zds_C PF08632.10 KUM57200.1 - 1.7e-27 94.9 1.6 3.2e-27 94.0 1.6 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Zn_clus PF00172.18 KUM57201.1 - 3.5e-09 36.6 11.4 5.9e-09 35.9 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 KUM57202.1 - 1.4e-38 132.6 4.7 2.1e-38 132.0 4.7 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4131 PF13567.6 KUM57202.1 - 5.4 6.6 7.2 1.6 8.3 3.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) AAA_22 PF13401.6 KUM57203.1 - 9.3e-05 22.7 0.1 0.19 12.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KUM57203.1 - 0.01 16.3 0.2 0.043 14.2 0.1 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KUM57203.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 KUM57203.1 - 0.031 13.5 0.0 0.08 12.2 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Adeno_IVa2 PF02456.15 KUM57203.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_16 PF13191.6 KUM57203.1 - 0.14 12.5 0.1 2.9 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain GPI-anchored PF10342.9 KUM57204.1 - 5.1e-18 65.6 1.0 5.1e-18 65.6 1.0 4.9 2 1 2 4 4 4 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ANAPC4_WD40 PF12894.7 KUM57205.1 - 8e-10 38.9 0.0 0.0028 17.9 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KUM57205.1 - 1.8e-08 34.9 15.3 0.00056 20.7 0.3 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat IKI3 PF04762.12 KUM57205.1 - 9.4e-06 23.9 0.0 0.0014 16.7 0.0 2.0 1 1 1 2 2 2 2 IKI3 family Cytochrom_D1 PF02239.16 KUM57205.1 - 0.016 13.8 0.0 0.03 12.9 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain eIF2A PF08662.11 KUM57205.1 - 0.032 14.1 0.1 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A EF_assoc_2 PF08356.12 KUM57206.1 - 1e-34 118.3 0.0 2e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KUM57206.1 - 7.8e-31 105.5 0.1 1.4e-30 104.7 0.1 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KUM57206.1 - 1.5e-24 86.4 0.0 2.2e-14 53.4 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KUM57206.1 - 1.6e-11 44.5 0.0 7.8e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KUM57206.1 - 5.9e-10 39.2 0.0 0.00015 21.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KUM57206.1 - 1.2e-07 30.7 1.0 0.0026 17.2 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KUM57206.1 - 1.3e-06 27.9 0.7 0.0039 17.0 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KUM57206.1 - 1.5e-05 25.4 0.2 0.0057 17.1 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair AAA_29 PF13555.6 KUM57206.1 - 2e-05 24.2 0.1 0.019 14.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KUM57206.1 - 4.5e-05 23.9 0.8 0.25 11.7 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KUM57206.1 - 0.00028 21.2 0.5 1.7 8.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KUM57206.1 - 0.00042 20.9 0.0 1.4 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KUM57206.1 - 0.00045 20.3 0.4 0.71 9.9 0.2 2.7 2 1 0 2 2 2 2 Dynamin family AAA_28 PF13521.6 KUM57206.1 - 0.00051 20.3 0.1 0.24 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 KUM57206.1 - 0.00059 19.4 0.1 4.9 6.6 0.0 3.2 2 1 0 3 3 3 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KUM57206.1 - 0.0012 18.8 0.1 1.6 8.6 0.0 3.4 3 0 0 3 3 3 1 RsgA GTPase EF-hand_8 PF13833.6 KUM57206.1 - 0.0017 18.1 0.4 0.54 10.1 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair Viral_helicase1 PF01443.18 KUM57206.1 - 0.0023 17.7 0.2 0.049 13.4 0.0 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase EF-hand_5 PF13202.6 KUM57206.1 - 0.0023 17.4 1.8 0.15 11.6 0.2 2.6 2 0 0 2 2 2 1 EF hand RNA_helicase PF00910.22 KUM57206.1 - 0.0065 16.8 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 KUM57206.1 - 0.0075 15.9 0.1 3.6 7.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KUM57206.1 - 0.0086 15.5 0.1 0.93 8.8 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.12 KUM57206.1 - 0.0086 16.0 0.2 4.6 7.1 0.0 2.7 3 0 0 3 3 2 0 NACHT domain ABC_tran PF00005.27 KUM57206.1 - 0.01 16.3 0.0 6.3 7.3 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 KUM57206.1 - 0.024 14.4 0.0 0.31 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KUM57206.1 - 0.03 14.5 0.0 7.7 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KUM57206.1 - 0.031 14.2 0.0 2.7 7.9 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 KUM57206.1 - 0.034 13.4 0.0 8.7 5.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin SMC_N PF02463.19 KUM57206.1 - 0.035 13.6 0.1 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 KUM57206.1 - 0.036 13.6 0.0 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region IIGP PF05049.13 KUM57206.1 - 0.051 12.6 0.2 0.91 8.5 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_5 PF07728.14 KUM57206.1 - 0.055 13.5 0.6 32 4.5 0.0 3.2 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KUM57206.1 - 0.074 12.2 0.2 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Septin PF00735.18 KUM57206.1 - 0.082 12.2 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Septin EF-hand_10 PF14788.6 KUM57206.1 - 0.1 12.5 0.8 0.71 9.8 0.1 2.2 2 0 0 2 2 2 0 EF hand AAA PF00004.29 KUM57206.1 - 0.14 12.6 0.5 17 5.8 0.0 3.1 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 KUM57206.1 - 0.17 10.9 0.0 4.8 6.2 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain DUF3201 PF11447.8 KUM57206.1 - 0.18 11.3 0.0 0.42 10.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) SPARC_Ca_bdg PF10591.9 KUM57206.1 - 0.31 11.4 0.9 5.7 7.3 0.1 2.9 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region cobW PF02492.19 KUM57206.1 - 0.43 10.2 1.7 9.1 5.8 0.1 3.5 4 1 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KUM57206.1 - 0.44 10.3 1.8 51 3.5 0.0 3.3 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein SPX PF03105.19 KUM57208.1 - 0.69 9.8 8.3 0.66 9.8 8.3 1.1 1 0 0 1 1 1 0 SPX domain QWRF PF04484.12 KUM57208.1 - 4 7.1 12.9 5.1 6.8 12.9 1.1 1 0 0 1 1 1 0 QWRF family Tmemb_cc2 PF10267.9 KUM57208.1 - 4.7 6.3 7.8 5.5 6.0 7.8 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SOG2 PF10428.9 KUM57208.1 - 5.5 6.1 16.9 5.8 6.0 16.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4118 PF13493.6 KUM57209.1 - 0.43 10.4 2.9 0.64 9.8 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) Amidohydro_3 PF07969.11 KUM57210.1 - 8.7e-66 223.3 1.4 9.9e-66 223.1 1.4 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KUM57210.1 - 2e-12 47.1 0.2 6.8e-07 28.9 0.1 2.8 2 1 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.16 KUM57212.1 - 2.6e-29 102.2 33.9 2.6e-29 102.2 33.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3007 PF11460.8 KUM57212.1 - 0.15 12.3 2.7 0.56 10.5 2.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) DUF423 PF04241.15 KUM57212.1 - 2 8.7 9.4 0.58 10.4 0.3 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF423) FA_desaturase PF00487.24 KUM57214.1 - 8e-13 48.8 22.3 8e-13 48.8 22.3 1.8 1 1 1 2 2 2 1 Fatty acid desaturase RseC_MucC PF04246.12 KUM57214.1 - 0.18 11.8 0.0 0.46 10.4 0.0 1.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF455 PF04305.14 KUM57215.1 - 1.4e-99 332.7 0.0 1.7e-99 332.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 KUM57215.1 - 6.9e-07 29.1 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KUM57215.1 - 1.9e-06 27.8 0.0 5e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Arylsulfotran_2 PF14269.6 KUM57217.1 - 1.8e-43 149.0 0.3 3.6e-43 148.1 0.0 1.6 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KUM57217.1 - 9.5e-18 64.3 0.0 2.8e-17 62.7 0.0 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) GREB1 PF15782.5 KUM57218.1 - 0.26 8.4 3.4 0.24 8.5 3.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 KUM57218.1 - 0.38 9.4 14.5 0.45 9.1 14.5 1.0 1 0 0 1 1 1 0 Hamartin protein DUF1712 PF08217.11 KUM57218.1 - 1.5 7.2 4.1 1.7 7.0 4.1 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) Glyco_hydro_11 PF00457.17 KUM57219.1 - 6.6e-79 263.7 20.0 7.7e-79 263.4 20.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Ank_2 PF12796.7 KUM57220.1 - 0.00018 22.0 0.0 0.00034 21.1 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM57220.1 - 0.00086 19.8 0.0 0.24 12.1 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM57220.1 - 0.0014 18.9 0.0 0.25 12.0 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KUM57220.1 - 0.0076 16.6 0.0 0.024 15.0 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KUM57220.1 - 0.067 13.7 0.1 0.74 10.4 0.0 2.5 3 0 0 3 3 3 0 Ankyrin repeat Glyco_transf_90 PF05686.12 KUM57222.1 - 7.7e-32 110.7 0.0 1.1e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KUM57222.1 - 0.00039 20.8 0.1 0.0007 19.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Kinesin PF00225.23 KUM57223.1 - 1.4e-110 369.4 0.0 2e-110 368.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 KUM57223.1 - 8.2e-45 153.2 0.2 2.4e-44 151.7 0.2 1.9 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 KUM57223.1 - 8.6e-38 130.3 7.5 1.2e-30 107.0 0.1 3.2 4 0 0 4 4 4 2 Kinesin-associated Microtub_bd PF16796.5 KUM57223.1 - 6.1e-24 84.7 0.0 1.9e-23 83.0 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 KUM57223.1 - 1.2e-07 32.0 0.1 4.6e-07 30.2 0.1 2.1 1 0 0 1 1 1 1 Kinesin protein 1B PH PF00169.29 KUM57223.1 - 8.1e-06 26.3 0.0 2.6e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 PH domain FHA PF00498.26 KUM57223.1 - 1.9e-05 24.9 0.1 0.00014 22.1 0.0 2.6 2 0 0 2 2 2 1 FHA domain UPF0242 PF06785.11 KUM57223.1 - 0.0071 16.5 7.0 1.4 8.9 0.1 2.6 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus Apolipoprotein PF01442.18 KUM57223.1 - 0.17 11.8 6.9 0.55 10.1 3.6 2.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain CBFB_NFYA PF02045.15 KUM57224.1 - 1.5e-28 99.2 4.6 3.1e-28 98.2 4.6 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.13 KUM57224.1 - 0.015 15.4 23.4 0.018 15.1 23.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hus1 PF04005.12 KUM57224.1 - 0.033 13.3 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein Sulfate_transp PF00916.20 KUM57225.1 - 7.1e-109 364.0 16.9 1.1e-108 363.4 16.9 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KUM57225.1 - 1.8e-06 27.5 0.0 3.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KUM57225.1 - 8.5e-05 22.9 3.6 8.5e-05 22.9 3.6 3.4 2 1 1 3 3 3 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 KUM57225.1 - 0.017 15.4 0.4 0.044 14.1 0.0 1.8 2 0 0 2 2 2 0 STAS domain SNN_transmemb PF09049.10 KUM57225.1 - 0.03 14.3 0.7 0.03 14.3 0.7 2.6 2 0 0 2 2 2 0 Stannin transmembrane Epiglycanin_C PF14654.6 KUM57225.1 - 0.49 10.5 2.7 0.76 9.9 0.7 2.3 1 1 1 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Filament PF00038.21 KUM57226.1 - 0.00045 19.9 6.1 0.00045 19.9 6.1 5.4 4 1 1 6 6 6 3 Intermediate filament protein MatP_C PF17414.2 KUM57226.1 - 0.3 11.3 5.2 0.65 10.2 3.1 2.8 2 1 0 2 2 2 0 MatP C-terminal ribbon-helix-helix domain DUF1449 PF07290.11 KUM57227.1 - 0.08 12.6 2.4 0.12 12.0 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) TMF_TATA_bd PF12325.8 KUM57229.1 - 5.3e-39 133.0 12.2 5.3e-39 133.0 12.2 6.9 2 1 5 8 8 8 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KUM57229.1 - 1.3e-20 73.1 17.0 1.3e-20 73.1 17.0 9.2 5 3 5 11 11 11 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KUM57229.1 - 1.6e-05 25.3 3.7 1.6e-05 25.3 3.7 5.9 2 1 4 6 6 6 3 Autophagy protein 16 (ATG16) BST2 PF16716.5 KUM57229.1 - 0.02 15.5 6.6 0.02 15.5 6.6 8.1 3 2 7 10 10 10 0 Bone marrow stromal antigen 2 DASH_Dam1 PF08653.10 KUM57229.1 - 0.65 9.8 6.6 2.8 7.8 0.1 4.4 2 2 2 4 4 4 0 DASH complex subunit Dam1 NPV_P10 PF05531.12 KUM57229.1 - 2.1 8.9 29.9 0.28 11.7 1.4 6.8 8 0 0 8 8 8 0 Nucleopolyhedrovirus P10 protein DUF4870 PF09685.10 KUM57230.1 - 0.12 12.5 0.0 0.12 12.5 0.0 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4870) MFS_1 PF07690.16 KUM57231.1 - 1.4e-30 106.5 38.3 1.4e-30 106.5 38.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily His_Phos_2 PF00328.22 KUM57232.1 - 1.9e-06 27.5 0.0 0.011 15.2 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) V-ATPase_H_N PF03224.14 KUM57235.1 - 1.3e-79 267.7 0.0 2e-79 267.1 0.0 1.3 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KUM57235.1 - 1.1e-36 125.5 0.1 4.2e-36 123.6 0.0 2.1 3 0 0 3 3 3 1 V-ATPase subunit H Fungal_trans_2 PF11951.8 KUM57236.1 - 2.1e-59 201.3 2.1 2.6e-59 201.0 2.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KUM57238.1 - 1.4e-22 80.0 0.4 2.4e-22 79.3 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Swi3 PF07962.12 KUM57238.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 Pkinase PF00069.25 KUM57239.1 - 2.5e-17 63.1 0.0 3.3e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM57239.1 - 6e-16 58.5 0.0 7.8e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KUM57239.1 - 0.0049 16.8 0.4 0.01 15.7 0.4 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KUM57239.1 - 0.0053 16.4 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KUM57239.1 - 0.037 13.3 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like CobT PF06213.12 KUM57239.1 - 0.3 10.4 8.7 0.4 10.0 8.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.9 KUM57239.1 - 0.33 10.0 20.2 0.45 9.6 20.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 KUM57239.1 - 4.5 6.5 10.9 6 6.1 10.9 1.1 1 0 0 1 1 1 0 BUD22 NAPRTase PF04095.16 KUM57240.1 - 4.1e-53 180.5 0.4 5.3e-52 176.8 0.4 2.0 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KUM57240.1 - 9.1e-26 90.7 0.0 1.6e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Cas_Csm6 PF09659.10 KUM57241.1 - 0.025 13.4 0.0 0.036 12.8 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) RHS_repeat PF05593.14 KUM57242.1 - 4.7e-17 62.1 45.7 0.0018 18.7 0.3 13.1 14 3 2 16 16 16 8 RHS Repeat DUF4112 PF13430.6 KUM57242.1 - 0.16 12.3 0.8 0.55 10.5 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4112) Cupin_1 PF00190.22 KUM57243.1 - 1.2e-35 122.3 0.0 2.9e-18 65.9 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KUM57243.1 - 4e-24 84.1 3.4 3.9e-11 42.5 0.1 2.7 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.12 KUM57243.1 - 9.8e-10 38.0 0.0 2.4e-05 23.9 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KUM57243.1 - 1.1e-06 28.7 0.1 0.0012 18.8 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Aa_trans PF01490.18 KUM57244.1 - 3.6e-38 131.4 35.5 4.3e-38 131.1 35.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 KUM57245.1 - 1.8e-35 122.6 35.5 2.1e-35 122.4 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_9_N PF15420.6 KUM57245.1 - 2.4 8.1 12.2 6.4 6.7 2.0 3.4 2 2 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus adh_short_C2 PF13561.6 KUM57246.1 - 6.1e-63 212.5 0.2 7e-63 212.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM57246.1 - 6.3e-42 143.2 0.1 7.5e-42 143.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM57246.1 - 3.3e-15 56.5 0.1 4.5e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 KR domain GH131_N PF18271.1 KUM57247.1 - 4.2e-66 223.3 0.9 4.7e-66 223.1 0.9 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Sugar_tr PF00083.24 KUM57248.1 - 2.1e-98 330.1 25.3 2.5e-98 329.9 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM57248.1 - 6.8e-24 84.5 25.9 6.8e-24 84.5 25.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM57248.1 - 8.3e-07 27.8 1.4 1.6e-06 26.8 1.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TPR_19 PF14559.6 KUM57248.1 - 0.058 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat MFS_1 PF07690.16 KUM57249.1 - 1.5e-41 142.5 31.7 2e-41 142.1 31.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM57249.1 - 6.5e-14 51.6 15.6 9.6e-14 51.1 15.3 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3302 PF11742.8 KUM57249.1 - 0.22 11.7 0.2 0.22 11.7 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3302) OATP PF03137.20 KUM57249.1 - 0.3 9.3 12.4 0.025 12.9 6.4 2.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF898 PF05987.13 KUM57249.1 - 1.3 8.0 10.3 23 3.9 10.4 2.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) SRP_SPB PF02978.19 KUM57250.1 - 0.029 15.0 1.2 0.035 14.7 1.2 1.4 1 1 0 1 1 1 0 Signal peptide binding domain DUF1275 PF06912.11 KUM57251.1 - 2.2e-44 151.7 17.4 2.5e-44 151.5 17.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Tmemb_185A PF10269.9 KUM57251.1 - 0.019 14.6 1.3 0.028 14.1 1.3 1.2 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein DUF2187 PF09953.9 KUM57251.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) MFS_1 PF07690.16 KUM57252.1 - 1.7e-26 93.0 33.9 1.7e-26 93.0 33.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM57252.1 - 1.8e-09 37.0 7.7 1.8e-09 37.0 7.7 2.0 1 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KUM57252.1 - 4.8e-06 25.3 2.2 8.2e-06 24.5 2.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Dioxygenase_C PF00775.21 KUM57253.1 - 6e-10 38.9 0.2 9.6e-10 38.2 0.2 1.3 1 0 0 1 1 1 1 Dioxygenase Lipoxygenase PF00305.19 KUM57254.1 - 2.9e-47 161.5 2.7 1.2e-46 159.4 2.7 2.0 1 1 0 1 1 1 1 Lipoxygenase PepX_C PF08530.10 KUM57256.1 - 4.2e-20 72.7 0.0 5.4e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain RE_HaeII PF09554.10 KUM57256.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 HaeII restriction endonuclease Fungal_trans_2 PF11951.8 KUM57257.1 - 5.8e-08 32.0 0.4 8.3e-07 28.1 0.1 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain DUF2313 PF10076.9 KUM57257.1 - 0.075 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) ABC_membrane PF00664.23 KUM57258.1 - 1.7e-97 326.4 38.6 6e-50 170.4 10.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KUM57258.1 - 3.9e-74 247.7 0.1 7.3e-36 123.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KUM57258.1 - 2.6e-12 46.6 3.6 0.00027 20.5 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KUM57258.1 - 6.2e-07 29.5 0.0 0.13 12.1 0.0 3.5 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KUM57258.1 - 1.2e-06 29.1 2.4 0.018 15.4 0.2 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KUM57258.1 - 2.5e-06 27.5 0.3 0.0091 15.8 0.0 3.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KUM57258.1 - 3.5e-06 27.3 1.2 0.085 13.1 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KUM57258.1 - 4.3e-06 26.4 1.0 0.082 12.7 0.5 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KUM57258.1 - 5.5e-06 26.3 0.0 0.025 14.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KUM57258.1 - 1.6e-05 23.9 4.6 0.045 12.6 0.1 3.3 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_5 PF07728.14 KUM57258.1 - 0.00038 20.5 0.2 2.7 8.0 0.0 3.8 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KUM57258.1 - 0.00042 20.1 1.6 0.88 9.3 0.8 3.7 3 1 0 3 3 3 1 AAA domain PRK PF00485.18 KUM57258.1 - 0.00071 19.4 0.0 0.28 10.9 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 KUM57258.1 - 0.001 19.4 0.7 1.2 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KUM57258.1 - 0.0012 19.4 0.0 1.7 9.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KUM57258.1 - 0.0012 19.0 0.1 0.13 12.3 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain Zeta_toxin PF06414.12 KUM57258.1 - 0.0012 18.2 0.1 0.4 9.9 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin ATP-synt_ab PF00006.25 KUM57258.1 - 0.0013 18.4 0.4 0.86 9.2 0.0 3.1 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 KUM57258.1 - 0.0014 18.2 0.4 0.68 9.5 0.1 3.1 3 0 0 3 3 2 1 AAA domain Dala_Dala_lig_N PF01820.21 KUM57258.1 - 0.0016 18.8 0.0 1.3 9.5 0.0 2.7 2 0 0 2 2 2 1 D-ala D-ala ligase N-terminus AAA_23 PF13476.6 KUM57258.1 - 0.0026 18.3 0.3 1.1 9.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 KUM57258.1 - 0.0035 17.4 0.0 9.3 6.3 0.0 3.7 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 KUM57258.1 - 0.0036 17.5 2.9 0.95 9.7 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KUM57258.1 - 0.0054 16.8 0.0 2.5 8.2 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase NB-ARC PF00931.22 KUM57258.1 - 0.0071 15.6 1.0 1.8 7.6 0.0 2.8 3 0 0 3 3 2 1 NB-ARC domain AAA PF00004.29 KUM57258.1 - 0.0081 16.6 4.8 5.9 7.3 0.3 4.3 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KUM57258.1 - 0.0086 16.5 0.0 8.6 6.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KUM57258.1 - 0.0088 16.2 0.0 7.7 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KUM57258.1 - 0.01 15.2 0.0 1.3 8.3 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KUM57258.1 - 0.012 15.3 0.4 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KUM57258.1 - 0.03 14.2 0.0 2 8.3 0.0 2.6 3 0 0 3 3 2 0 Rad17 P-loop domain AAA_7 PF12775.7 KUM57258.1 - 0.037 13.5 0.1 11 5.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region APS_kinase PF01583.20 KUM57258.1 - 0.05 13.5 0.3 10 6.0 0.0 3.0 3 0 0 3 3 3 0 Adenylylsulphate kinase NACHT PF05729.12 KUM57258.1 - 0.073 13.0 1.7 6.1 6.7 0.2 2.6 2 0 0 2 2 2 0 NACHT domain G-alpha PF00503.20 KUM57258.1 - 0.075 12.2 0.1 9.2 5.3 0.0 2.5 3 0 0 3 3 3 0 G-protein alpha subunit Spectrin PF00435.21 KUM57260.1 - 0.017 15.6 0.2 0.033 14.7 0.2 1.4 1 0 0 1 1 1 0 Spectrin repeat Bac_export_3 PF01313.19 KUM57261.1 - 0.015 15.2 1.6 0.028 14.3 1.6 1.4 1 0 0 1 1 1 0 Bacterial export proteins, family 3 DUF3723 PF12520.8 KUM57262.1 - 4.2e-44 151.1 0.1 5.7e-44 150.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) S36_mt PF10937.8 KUM57262.1 - 0.11 14.1 2.4 2.9 9.5 0.0 3.1 2 1 1 3 3 3 0 Ribosomal protein S36, mitochondrial F-box-like PF12937.7 KUM57263.1 - 1.1e-06 28.4 1.1 1.1e-06 28.4 1.1 1.7 2 0 0 2 2 2 1 F-box-like Nop14 PF04147.12 KUM57263.1 - 0.069 11.4 6.5 0.079 11.2 6.5 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4692 PF15763.5 KUM57263.1 - 0.24 11.9 2.9 0.45 11.0 2.9 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Utp14 PF04615.13 KUM57263.1 - 0.27 9.7 6.9 0.34 9.4 6.9 1.1 1 0 0 1 1 1 0 Utp14 protein SDA1 PF05285.12 KUM57263.1 - 0.54 9.6 12.9 0.67 9.3 12.9 1.1 1 0 0 1 1 1 0 SDA1 SGT1 PF07093.11 KUM57263.1 - 0.81 8.1 4.3 0.98 7.8 4.3 1.2 1 0 0 1 1 1 0 SGT1 protein YL1 PF05764.13 KUM57263.1 - 2.3 8.3 6.9 2.9 7.9 6.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 KUM57263.1 - 2.4 6.4 9.0 2.8 6.1 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein AHH PF14412.6 KUM57265.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH NAD_binding_4 PF07993.12 KUM57266.1 - 4.7e-43 147.2 0.0 8.1e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KUM57266.1 - 2.9e-12 46.7 0.0 7.3e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KUM57266.1 - 8.4e-10 38.5 0.0 1.7e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KUM57266.1 - 0.00082 18.5 0.0 0.88 8.5 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KUM57266.1 - 0.047 13.1 0.9 0.28 10.5 0.8 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase GMC_oxred_N PF00732.19 KUM57267.1 - 2.2e-45 155.3 0.0 3.4e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM57267.1 - 5.2e-34 117.8 0.1 8.4e-34 117.2 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase 2OG-FeII_Oxy_2 PF13532.6 KUM57268.1 - 3e-38 132.0 0.2 4.1e-38 131.5 0.2 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KUM57268.1 - 0.00024 21.1 5.6 0.00048 20.2 5.6 1.5 1 0 0 1 1 1 1 GRF zinc finger DMA PF03474.14 KUM57268.1 - 0.035 13.7 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 DMRTA motif CUE PF02845.16 KUM57268.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 CUE domain p47_phox_C PF08944.11 KUM57270.1 - 0.075 12.5 0.8 0.16 11.4 0.8 1.5 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Asp_Glu_race PF01177.22 KUM57272.1 - 9.2e-43 146.7 0.3 9.6e-43 146.6 0.3 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase SH3_4 PF06347.13 KUM57274.1 - 0.17 11.8 0.5 0.32 10.9 0.5 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain FtsK_SpoIIIE PF01580.18 KUM57275.1 - 0.033 13.6 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 KUM57275.1 - 0.064 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin UQ_con PF00179.26 KUM57276.1 - 1.2e-10 41.2 0.0 2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Fungal_trans PF04082.18 KUM57277.1 - 0.0018 17.3 0.1 0.0041 16.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1885 PF08968.10 KUM57277.1 - 0.17 12.0 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) DIOX_N PF14226.6 KUM57278.1 - 8.8e-34 116.8 0.1 1.2e-33 116.3 0.1 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Pectinesterase PF01095.19 KUM57279.1 - 1.2e-26 93.2 0.1 7.5e-21 74.1 0.1 2.1 2 0 0 2 2 2 2 Pectinesterase F-box PF00646.33 KUM57280.1 - 6.8e-05 22.6 0.8 0.00019 21.2 0.7 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KUM57280.1 - 0.0081 16.0 0.3 0.022 14.7 0.3 1.7 1 0 0 1 1 1 1 F-box-like Sugar_tr PF00083.24 KUM57281.1 - 1.6e-126 422.8 21.8 1.8e-126 422.6 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM57281.1 - 5.5e-24 84.7 24.1 5.5e-24 84.7 24.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM57282.1 - 1.8e-46 158.9 8.6 2.5e-46 158.5 8.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM57282.1 - 2.1e-05 23.6 7.0 2.1e-05 23.6 7.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DDOST_48kD PF03345.14 KUM57282.1 - 0.045 12.6 0.0 0.066 12.0 0.0 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta DUF4383 PF14325.6 KUM57282.1 - 0.053 13.8 9.1 0.38 11.1 9.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) Sugar_tr PF00083.24 KUM57283.1 - 1.9e-08 33.6 0.0 2.8e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM57283.1 - 2e-05 23.7 0.3 2.8e-05 23.2 0.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.18 KUM57284.1 - 4.2e-07 30.0 10.2 1e-06 28.7 10.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNARE PF05739.19 KUM57285.1 - 3.3e-10 39.8 0.1 8.8e-10 38.4 0.1 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 KUM57285.1 - 6.8e-07 28.3 0.0 1.9e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain KxDL PF10241.9 KUM57285.1 - 6.3e-05 23.2 0.2 0.16 12.3 0.1 2.8 2 0 0 2 2 2 2 Uncharacterized conserved protein Syntaxin PF00804.25 KUM57285.1 - 0.0067 16.1 7.7 0.025 14.3 0.1 2.8 2 1 0 3 3 3 2 Syntaxin SPATA48 PF15073.6 KUM57285.1 - 0.032 14.5 0.3 0.092 13.0 0.3 1.8 1 0 0 1 1 1 0 Spermatogenesis-associated protein 48 DUF4988 PF16378.5 KUM57285.1 - 0.039 13.6 4.2 17 5.0 0.1 3.1 2 1 0 3 3 3 0 Domain of unknown function NPV_P10 PF05531.12 KUM57285.1 - 0.24 11.9 2.2 79 3.8 0.0 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 KUM57285.1 - 2 8.9 4.4 1.3 9.5 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 MFS_1 PF07690.16 KUM57289.1 - 3.8e-15 55.7 63.9 3.3e-13 49.3 60.9 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM57289.1 - 4.2e-12 45.3 29.8 5.7e-12 44.8 29.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 KUM57289.1 - 0.0022 18.1 1.2 0.014 15.5 1.2 2.5 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 Arylsulfotran_2 PF14269.6 KUM57290.1 - 3.2e-117 391.2 5.5 4.7e-117 390.6 5.5 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KUM57290.1 - 1.5e-11 43.9 3.2 1.7e-10 40.4 3.2 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) AA_permease PF00324.21 KUM57291.1 - 1.6e-135 452.4 42.9 1.8e-135 452.3 42.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM57291.1 - 9e-36 123.6 49.6 1.1e-35 123.3 49.6 1.0 1 0 0 1 1 1 1 Amino acid permease TRI5 PF06330.11 KUM57292.1 - 3.5e-18 65.6 0.6 4.3e-18 65.3 0.6 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) SVM_signal PF12113.8 KUM57292.1 - 0.15 12.0 0.3 0.31 11.0 0.3 1.6 1 0 0 1 1 1 0 SVM protein signal sequence Acetyltransf_1 PF00583.25 KUM57293.1 - 2e-12 47.4 0.1 4.7e-12 46.2 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KUM57293.1 - 1.5e-11 44.5 0.0 2.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KUM57293.1 - 4.6e-11 42.7 0.0 1.6e-10 41.0 0.0 1.6 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KUM57293.1 - 9.2e-05 22.5 0.1 0.0011 19.0 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KUM57293.1 - 0.0072 16.4 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KUM57293.1 - 0.049 13.6 0.0 0.16 11.9 0.0 1.9 1 1 0 1 1 1 0 FR47-like protein Pyr_redox_2 PF07992.14 KUM57294.1 - 9.6e-22 77.5 0.0 3.7e-21 75.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM57294.1 - 5.5e-12 46.1 1.1 7.1e-10 39.3 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM57294.1 - 1.1e-05 24.9 0.0 0.00037 19.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM57294.1 - 0.00029 20.1 0.1 0.00047 19.4 0.1 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KUM57294.1 - 0.0039 16.1 0.1 1.3 7.8 0.8 2.7 3 0 0 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.12 KUM57294.1 - 0.0052 15.9 0.0 0.011 14.8 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KUM57294.1 - 0.046 13.0 0.2 0.39 10.0 0.3 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KUM57294.1 - 0.052 13.5 0.7 3.8 7.5 0.0 3.4 4 0 0 4 4 4 0 FAD-NAD(P)-binding DAO PF01266.24 KUM57294.1 - 0.057 13.0 0.4 0.87 9.1 0.4 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 KUM57294.1 - 0.11 11.6 0.1 1.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KUM57294.1 - 0.13 10.9 0.4 0.45 9.2 0.2 1.9 3 0 0 3 3 3 0 HI0933-like protein ABC_membrane PF00664.23 KUM57295.1 - 2.8e-85 286.3 31.8 2.5e-48 165.1 11.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KUM57295.1 - 1.3e-66 223.3 0.0 6.3e-33 114.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KUM57295.1 - 1.9e-16 60.2 0.1 1.1e-05 25.0 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KUM57295.1 - 2.5e-07 31.2 1.4 0.027 14.8 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KUM57295.1 - 2.7e-07 30.2 0.6 0.0052 16.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KUM57295.1 - 2e-06 28.2 0.3 0.11 12.7 0.1 4.1 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KUM57295.1 - 8.2e-05 22.4 4.1 0.053 13.2 0.1 3.5 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KUM57295.1 - 8.5e-05 22.5 0.0 0.059 13.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase ABC_ATPase PF09818.9 KUM57295.1 - 0.00016 20.6 0.0 0.016 14.0 0.0 2.6 2 0 0 2 2 2 1 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 KUM57295.1 - 0.00029 20.2 0.3 0.53 9.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin APS_kinase PF01583.20 KUM57295.1 - 0.00035 20.5 0.3 0.2 11.5 0.1 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.6 KUM57295.1 - 0.0012 19.0 0.0 2.3 8.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 KUM57295.1 - 0.0013 18.4 0.0 2.5 7.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KUM57295.1 - 0.0022 18.2 0.2 3.1 8.1 0.0 3.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KUM57295.1 - 0.0025 18.4 1.1 1.3 9.5 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_21 PF13304.6 KUM57295.1 - 0.0043 16.9 0.8 0.21 11.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KUM57295.1 - 0.0069 16.9 0.1 1.3 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Tex_YqgF PF16921.5 KUM57295.1 - 0.0073 16.8 0.5 0.018 15.5 0.5 1.7 1 0 0 1 1 1 1 Tex protein YqgF-like domain AAA PF00004.29 KUM57295.1 - 0.012 16.1 0.5 47 4.4 0.0 4.2 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 KUM57295.1 - 0.012 15.7 0.1 2.5 8.1 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 KUM57295.1 - 0.013 15.3 0.0 4.9 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 KUM57295.1 - 0.017 14.2 0.0 1 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_5 PF07728.14 KUM57295.1 - 0.026 14.5 0.0 6.1 6.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KUM57295.1 - 0.033 14.3 0.0 5.5 7.1 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 KUM57295.1 - 0.08 12.1 0.1 14 4.8 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_7 PF12775.7 KUM57295.1 - 0.092 12.3 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_17 PF13207.6 KUM57295.1 - 0.18 12.2 0.7 37 4.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain Acetyltransf_8 PF13523.6 KUM57296.1 - 1.6e-43 147.8 0.9 2.4e-43 147.3 0.9 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 KUM57297.1 - 9.3e-78 261.7 0.0 3.7e-77 259.7 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 KUM57297.1 - 4.9e-64 216.7 0.0 9.5e-37 126.7 0.0 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KUM57297.1 - 3.1e-24 85.1 1.0 9.4e-13 48.3 0.2 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site DUF2433 PF10360.9 KUM57298.1 - 0.029 14.4 0.1 0.062 13.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2433) Alpha-amylase PF00128.24 KUM57299.1 - 7.8e-46 157.2 0.0 1.2e-45 156.6 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KUM57299.1 - 1.5e-21 76.5 0.2 3.4e-21 75.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Alpha-amylase PF00128.24 KUM57300.1 - 6.3e-21 75.3 0.0 1.8e-20 73.8 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KUM57300.1 - 6.4e-15 55.5 0.1 1.1e-14 54.8 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KUM57300.1 - 8.8e-06 25.4 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KUM57300.1 - 1.9 8.9 5.0 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain adh_short_C2 PF13561.6 KUM57301.1 - 5.9e-44 150.4 0.0 7.3e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM57301.1 - 6.3e-35 120.4 0.1 7.3e-35 120.2 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM57301.1 - 1e-10 41.8 0.1 1.2e-10 41.6 0.1 1.1 1 0 0 1 1 1 1 KR domain GPI-anchored PF10342.9 KUM57302.1 - 1.3e-13 51.5 2.2 1.3e-13 51.5 2.2 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family QWRF PF04484.12 KUM57302.1 - 0.7 9.6 16.9 0.76 9.5 16.9 1.2 1 0 0 1 1 1 0 QWRF family SOG2 PF10428.9 KUM57302.1 - 0.83 8.8 29.5 0.99 8.5 29.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Hid1 PF12722.7 KUM57302.1 - 1.1 7.3 9.7 1.2 7.2 9.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Apt1 PF10351.9 KUM57302.1 - 4.7 6.0 21.3 5.9 5.6 21.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SWI-SNF_Ssr4 PF08549.10 KUM57302.1 - 5.9 5.4 12.6 8.7 4.8 12.6 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) GREB1 PF15782.5 KUM57302.1 - 6.5 3.7 13.4 6.9 3.6 13.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAD_binding_3 PF01494.19 KUM57303.1 - 7.8e-27 94.4 0.0 2.3e-26 92.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KUM57303.1 - 6.2e-05 23.1 0.3 0.00017 21.7 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KUM57303.1 - 0.00014 21.2 0.9 0.071 12.4 0.6 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM57303.1 - 0.0013 18.1 0.1 0.017 14.4 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM57303.1 - 0.0041 16.8 0.3 0.02 14.5 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 KUM57303.1 - 0.0052 15.9 0.0 0.51 9.3 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Amino_oxidase PF01593.24 KUM57303.1 - 0.02 14.2 0.1 3.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KUM57303.1 - 0.03 13.4 1.6 0.048 12.7 0.9 1.6 2 0 0 2 2 2 0 FAD binding domain Fungal_trans_2 PF11951.8 KUM57304.1 - 3.3e-08 32.8 0.0 4e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain RelB_transactiv PF16181.5 KUM57304.1 - 0.03 14.6 0.2 0.049 13.9 0.2 1.3 1 0 0 1 1 1 0 RelB transactivation domain DUF4535 PF15054.6 KUM57305.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) DEAD PF00270.29 KUM57306.1 - 5.5e-33 114.2 0.2 1.2e-32 113.0 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM57306.1 - 1.5e-23 83.3 0.0 3.4e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IMPa_N_2 PF18650.1 KUM57306.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain Fungal_trans PF04082.18 KUM57307.1 - 2.4e-08 33.4 0.2 1.2e-07 31.0 0.1 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain TAP_C PF03943.13 KUM57307.1 - 0.016 14.9 0.2 0.055 13.1 0.2 1.9 1 0 0 1 1 1 0 TAP C-terminal domain SH3_9 PF14604.6 KUM57309.1 - 1.1e-22 79.6 0.8 1.4e-11 44.0 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KUM57309.1 - 1.9e-17 62.6 0.9 3.7e-09 36.1 0.0 2.7 3 0 0 3 3 3 2 SH3 domain C1_1 PF00130.22 KUM57309.1 - 2.3e-15 56.2 5.6 3.4e-15 55.7 5.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_10 PF17902.1 KUM57309.1 - 0.001 19.1 0.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 2 SH3 domain C1_2 PF03107.16 KUM57309.1 - 0.0048 17.2 4.2 0.008 16.5 4.2 1.3 1 0 0 1 1 1 1 C1 domain SH3_2 PF07653.17 KUM57309.1 - 0.006 16.2 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 KUM57309.1 - 0.11 12.8 0.3 1.6 9.1 0.1 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain Cortex-I_coil PF09304.10 KUM57309.1 - 0.19 12.0 1.8 0.37 11.0 0.1 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil OrfB_Zn_ribbon PF07282.11 KUM57309.1 - 3.6 7.6 5.2 7.8 6.5 5.2 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-RING_9 PF13901.6 KUM57309.1 - 8.8 6.2 9.1 77 3.2 9.1 2.2 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon GTP_CH_N PF12471.8 KUM57311.1 - 2.6e-88 294.8 0.0 3.7e-88 294.3 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KUM57311.1 - 1.5e-17 63.6 0.0 2.2e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II FSH1 PF03959.13 KUM57312.1 - 2.7e-30 105.6 0.0 4.8e-30 104.8 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF3632 PF12311.8 KUM57313.1 - 3e-27 96.2 0.7 4.8e-27 95.5 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) NAD_binding_6 PF08030.12 KUM57314.1 - 6.1e-19 68.7 0.0 1.7e-18 67.2 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KUM57314.1 - 1.1e-18 67.5 12.5 3.4e-18 66.0 12.5 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KUM57314.1 - 5.2e-12 45.8 0.0 1.5e-08 34.7 0.0 2.9 3 0 0 3 3 3 2 FAD-binding domain DUF4964 PF16334.5 KUM57314.1 - 0.048 13.2 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4964) NAD_binding_1 PF00175.21 KUM57314.1 - 0.059 14.0 0.1 0.75 10.5 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF2014 PF09427.10 KUM57315.1 - 1.4e-98 329.4 0.2 2.1e-98 328.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 KUM57315.1 - 1.9e-18 66.1 0.4 4.5e-18 65.0 0.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CCDC85 PF10226.9 KUM57315.1 - 0.23 11.1 1.3 0.4 10.3 1.3 1.4 1 0 0 1 1 1 0 CCDC85 family ADH_zinc_N PF00107.26 KUM57316.1 - 9.7e-12 45.0 0.0 1.8e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM57316.1 - 6.8e-06 25.9 0.1 0.00012 21.9 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KUM57316.1 - 0.0022 19.1 0.0 0.0069 17.4 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Phosphorylase PF00343.20 KUM57317.1 - 0 1054.0 0.0 0 1053.8 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase AAA_35 PF14516.6 KUM57317.1 - 0.058 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF4366 PF14283.6 KUM57318.1 - 0.00083 19.4 0.2 0.00087 19.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) NapE PF06796.11 KUM57318.1 - 0.045 13.3 0.6 0.071 12.6 0.6 1.4 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE CENP-B_dimeris PF09026.10 KUM57318.1 - 0.1 13.0 5.3 0.096 13.1 5.3 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GSK-3_bind PF05350.12 KUM57318.1 - 1.9 7.8 7.6 2.1 7.6 7.6 1.0 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Cytomega_UL84 PF06284.11 KUM57318.1 - 2.8 6.3 3.5 2.8 6.3 3.5 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Radial_spoke PF04712.12 KUM57318.1 - 8.2 5.2 16.0 8.6 5.2 16.0 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein End3 PF12761.7 KUM57319.1 - 4.5e-68 229.3 0.3 6.6e-68 228.8 0.3 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KUM57319.1 - 2.7e-51 171.9 0.2 4.1e-48 161.6 0.3 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KUM57319.1 - 6.4e-08 31.6 0.2 2.6e-07 29.7 0.3 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KUM57319.1 - 1.3e-06 28.8 0.4 4.9e-06 26.9 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KUM57319.1 - 0.00011 21.8 0.2 0.00064 19.5 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KUM57319.1 - 0.0021 17.5 0.2 0.0081 15.6 0.2 2.0 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KUM57319.1 - 0.0032 17.3 0.0 0.0068 16.2 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair DUF4407 PF14362.6 KUM57319.1 - 0.42 9.9 2.1 0.62 9.4 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 KUM57319.1 - 2 8.5 7.1 1.1 9.4 0.7 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KUM57319.1 - 7.4 5.3 7.8 0.87 8.4 2.6 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Aldo_ket_red PF00248.21 KUM57320.1 - 1.5e-41 142.5 0.0 1.9e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 KUM57322.1 - 4.9e-67 226.1 0.0 6.5e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM57322.1 - 9.9e-32 110.2 0.0 1.3e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KUM57322.1 - 1.1e-05 24.6 0.1 1.5e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KUM57322.1 - 0.00015 21.2 0.1 0.00053 19.4 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KUM57322.1 - 0.00051 19.4 0.0 0.046 13.0 0.0 2.3 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 KUM57322.1 - 0.0009 19.2 0.0 0.0024 17.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KUM57322.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KUM57322.1 - 0.047 13.3 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family G-alpha PF00503.20 KUM57323.1 - 3.5e-29 102.1 0.0 3.9e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Cupin_2 PF07883.11 KUM57324.1 - 4.2e-07 29.6 0.4 8.2e-07 28.7 0.4 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KUM57324.1 - 6.8e-07 29.0 0.1 9.1e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 KUM57324.1 - 0.0018 18.5 0.1 0.0029 17.8 0.1 1.4 1 1 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.7 KUM57324.1 - 0.0084 15.9 0.0 0.0096 15.7 0.0 1.1 1 0 0 1 1 1 1 Cupin Cullin PF00888.22 KUM57325.1 - 1.4e-193 645.0 14.7 1.9e-193 644.5 14.7 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KUM57325.1 - 1.3e-26 92.4 3.5 1.3e-26 92.4 3.5 2.4 3 0 0 3 3 3 1 Cullin protein neddylation domain Avl9 PF09794.9 KUM57326.1 - 4.4e-136 453.5 0.0 5.8e-136 453.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 KUM57326.1 - 1.8e-06 27.9 0.1 0.0078 16.2 0.0 2.5 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 KUM57326.1 - 0.00029 20.5 3.3 0.03 13.9 0.2 3.4 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2347) Uds1 PF15456.6 KUM57326.1 - 0.43 10.8 3.7 0.73 10.0 2.6 1.9 2 0 0 2 2 2 0 Up-regulated During Septation Mit_KHE1 PF10173.9 KUM57328.1 - 4.6e-61 206.2 0.4 4.6e-61 206.2 0.4 1.6 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related MARVEL PF01284.23 KUM57329.1 - 0.12 12.4 1.4 0.19 11.7 1.4 1.3 1 0 0 1 1 1 0 Membrane-associating domain BBE PF08031.12 KUM57330.1 - 1e-09 38.3 0.2 2e-09 37.4 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 KUM57330.1 - 2.9e-09 36.8 3.8 4.8e-09 36.1 3.3 1.6 1 1 0 1 1 1 1 FAD binding domain Cytokin-bind PF09265.10 KUM57330.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding tRNA-synt_1c PF00749.21 KUM57331.1 - 1.3e-91 306.8 0.0 1.6e-91 306.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain RFC1 PF08519.12 KUM57331.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain ABC_tran PF00005.27 KUM57332.1 - 2.3e-31 109.1 0.1 3.9e-31 108.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KUM57332.1 - 5.9e-08 32.4 0.5 7.9e-07 28.7 0.2 2.0 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KUM57332.1 - 6.6e-07 29.4 0.1 0.00021 21.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 KUM57332.1 - 0.0029 17.4 0.4 0.87 9.3 0.0 2.2 2 0 0 2 2 2 2 IstB-like ATP binding protein DEAD PF00270.29 KUM57332.1 - 0.003 17.4 0.4 0.016 15.0 0.4 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_18 PF13238.6 KUM57332.1 - 0.0047 17.5 0.0 0.029 14.9 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.6 KUM57332.1 - 0.013 15.1 0.1 0.045 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KUM57332.1 - 0.017 15.4 0.3 0.078 13.3 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KUM57332.1 - 0.043 13.6 0.1 0.13 12.0 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 KUM57332.1 - 0.044 13.9 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_33 PF13671.6 KUM57332.1 - 0.051 13.7 0.4 0.2 11.8 0.4 2.2 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KUM57332.1 - 0.13 12.3 0.2 0.44 10.6 0.0 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase 4HBT PF03061.22 KUM57333.1 - 7.9e-14 51.8 0.0 1.5e-13 50.9 0.0 1.5 1 1 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KUM57333.1 - 7.7e-05 23.2 0.0 0.00012 22.5 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KUM57333.1 - 0.00069 19.0 0.2 0.001 18.4 0.2 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase Hexapep PF00132.24 KUM57334.1 - 2.3e-07 30.3 13.3 0.00049 19.7 0.7 3.6 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KUM57334.1 - 1.6e-05 24.1 2.8 5e-05 22.4 2.8 1.7 1 1 0 1 1 1 1 L-fucokinase Clathrin_bdg PF15045.6 KUM57334.1 - 0.028 14.4 0.1 8.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking DUF4954 PF16314.5 KUM57334.1 - 0.047 11.8 0.9 0.068 11.3 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Aa_trans PF01490.18 KUM57337.1 - 2.3e-30 105.6 22.7 3.3e-30 105.1 22.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Abhydrolase_6 PF12697.7 KUM57338.1 - 7.6e-20 72.5 0.2 9.2e-20 72.2 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM57338.1 - 1.3e-19 70.9 0.0 1.7e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM57338.1 - 6.1e-09 35.5 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KUM57338.1 - 2.5e-05 24.0 0.0 3.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 KUM57338.1 - 2.9e-05 23.5 0.0 0.0029 17.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) UPF0227 PF05728.12 KUM57338.1 - 0.00048 20.1 0.1 0.00091 19.2 0.1 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Peptidase_S9 PF00326.21 KUM57338.1 - 0.0011 18.5 0.0 0.0052 16.3 0.0 2.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family Thioesterase PF00975.20 KUM57338.1 - 0.004 17.3 0.0 0.008 16.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase PF07224.11 KUM57338.1 - 0.022 13.8 0.1 0.065 12.2 0.1 1.7 1 1 0 1 1 1 0 Chlorophyllase DUF1057 PF06342.12 KUM57338.1 - 0.031 13.3 0.1 0.096 11.7 0.1 1.6 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Palm_thioest PF02089.15 KUM57338.1 - 0.043 13.6 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PGAP1 PF07819.13 KUM57338.1 - 0.061 13.0 0.0 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Chlorophyllase2 PF12740.7 KUM57338.1 - 0.067 12.1 0.1 0.22 10.4 0.1 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KUM57338.1 - 0.082 12.7 0.1 1.6 8.5 0.1 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ku PF02735.16 KUM57338.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain DnaJ_C PF01556.18 KUM57339.1 - 5.5e-36 123.9 0.2 8.4e-36 123.3 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KUM57339.1 - 4.6e-20 71.5 4.5 1.1e-19 70.3 4.5 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KUM57339.1 - 3.1e-13 49.9 21.5 5.3e-13 49.1 21.5 1.4 1 0 0 1 1 1 1 DnaJ central domain RseC_MucC PF04246.12 KUM57339.1 - 0.12 12.3 0.3 0.12 12.3 0.3 2.2 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC HypA PF01155.19 KUM57339.1 - 1.1 9.3 11.9 2.3 8.2 2.1 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1356 PF07092.12 KUM57339.1 - 3.9 6.7 5.9 14 4.8 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) zf-RING_10 PF16685.5 KUM57339.1 - 9.7 6.4 10.6 2.5 8.3 0.7 2.2 1 1 1 2 2 2 0 zinc RING finger of MSL2 Sugar_tr PF00083.24 KUM57340.1 - 2.4e-118 395.9 31.9 2.7e-118 395.7 31.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM57340.1 - 4.7e-22 78.4 46.7 6.1e-20 71.4 32.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 KUM57340.1 - 5.4 6.6 9.2 16 5.1 0.4 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Sedlin_N PF04628.13 KUM57341.1 - 9e-13 48.5 0.0 1.3e-12 48.0 0.0 1.3 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region HABP4_PAI-RBP1 PF04774.15 KUM57343.1 - 0.15 12.9 5.4 0.24 12.3 5.4 1.6 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family Ribosomal_S3Ae PF01015.18 KUM57344.1 - 6.3e-88 293.6 3.6 7.8e-88 293.3 3.6 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 KUM57344.1 - 0.015 15.8 0.1 0.16 12.5 0.0 2.3 2 0 0 2 2 2 0 Translation initiation factor SUI1 NEMO PF11577.8 KUM57344.1 - 0.095 12.7 0.3 0.86 9.7 0.0 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Acyl_transf_1 PF00698.21 KUM57345.1 - 3.3e-21 76.1 0.1 9.8e-14 51.6 0.1 2.1 2 0 0 2 2 2 2 Acyl transferase domain Phage_portal_2 PF05136.13 KUM57345.1 - 0.071 12.3 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Phage portal protein, lambda family UPRTase PF14681.6 KUM57346.1 - 3.2e-78 261.9 0.0 3.7e-78 261.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KUM57346.1 - 0.0042 16.6 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 KUM57346.1 - 0.22 11.5 0.2 0.34 10.9 0.2 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Ras PF00071.22 KUM57347.1 - 1.8e-45 154.5 0.1 2e-45 154.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM57347.1 - 1.4e-16 60.7 0.0 1.9e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM57347.1 - 2.4e-08 33.6 0.0 2.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KUM57347.1 - 2.5e-05 24.3 0.0 3.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KUM57347.1 - 3.1e-05 23.6 0.5 0.00065 19.3 0.2 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KUM57347.1 - 0.00035 20.1 0.0 0.00046 19.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KUM57347.1 - 0.0014 18.5 0.1 0.27 11.1 0.0 2.1 1 1 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 KUM57347.1 - 0.0061 16.8 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KUM57347.1 - 0.024 14.7 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KUM57347.1 - 0.037 13.6 0.0 0.21 11.1 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 KUM57347.1 - 0.18 11.2 0.0 0.4 10.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein WAPL PF07814.13 KUM57348.1 - 5.3e-75 252.5 0.7 7.2e-75 252.1 0.7 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Elf1 PF05129.13 KUM57349.1 - 3.4e-29 100.7 0.2 4.5e-29 100.3 0.2 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.15 KUM57349.1 - 0.039 14.0 0.3 1.1 9.3 0.1 2.4 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger EST1_DNA_bind PF10373.9 KUM57349.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Oxidored_q6 PF01058.22 KUM57350.1 - 1.2e-22 80.1 0.0 2e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit tRNA-synt_2b PF00587.25 KUM57351.1 - 9.3e-38 130.0 0.3 2.8e-37 128.4 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KUM57351.1 - 1.1e-18 67.4 5.8 1.1e-18 67.4 5.8 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Cytochrom_C552 PF02335.15 KUM57351.1 - 0.19 10.6 9.7 0.26 10.2 0.3 2.2 2 0 0 2 2 2 0 Cytochrome c552 Nucleoporin_C PF03177.14 KUM57352.1 - 8.2e-170 566.4 0.0 9.8e-170 566.2 0.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KUM57352.1 - 1.2e-78 264.8 0.0 1.5e-78 264.5 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Glyco_hydro_43 PF04616.14 KUM57354.1 - 3.9e-42 144.5 0.4 5.4e-42 144.1 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PX PF00787.24 KUM57355.1 - 4.2e-17 62.2 0.0 2.5e-16 59.7 0.0 2.2 3 0 0 3 3 3 1 PX domain Vps5 PF09325.10 KUM57355.1 - 3.3e-06 26.8 9.6 0.0052 16.4 2.0 2.2 2 0 0 2 2 2 2 Vps5 C terminal like Peptidase_C10 PF01640.17 KUM57355.1 - 0.041 14.2 0.0 0.1 12.9 0.0 1.6 2 0 0 2 2 2 0 Peptidase C10 family DUF2428 PF10350.9 KUM57356.1 - 3.9e-63 213.3 0.0 8.5e-63 212.2 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KUM57356.1 - 3.6e-05 23.6 6.2 5.5 7.5 0.1 6.4 6 0 0 6 6 6 2 HEAT repeat Tim17 PF02466.19 KUM57357.1 - 2.1e-25 89.2 5.6 2.8e-25 88.8 5.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Fungal_trans_2 PF11951.8 KUM57358.1 - 3.1e-34 118.4 5.5 4.1e-34 118.0 5.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM57358.1 - 2e-11 43.8 7.4 3.7e-11 42.9 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclase PF04199.13 KUM57359.1 - 2.4e-10 40.8 0.0 3.2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Pkinase PF00069.25 KUM57360.1 - 1.3e-43 149.3 0.0 4.8e-42 144.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM57360.1 - 1.3e-25 90.2 0.0 2.2e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KUM57360.1 - 0.0001 21.2 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KUM57360.1 - 0.00098 18.5 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 KUM57362.1 - 6.8e-10 38.7 0.0 5.3e-05 22.7 0.0 3.2 3 1 0 3 3 3 2 Protein kinase domain Brix PF04427.18 KUM57363.1 - 3.9e-33 115.2 0.0 5.9e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 Brix domain NUP50 PF08911.11 KUM57363.1 - 0.37 11.5 3.1 1.7 9.4 3.1 2.2 1 1 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) zf-rbx1 PF12678.7 KUM57364.1 - 1.4e-08 34.9 5.0 5.5e-08 33.0 5.0 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KUM57364.1 - 3e-08 33.9 3.2 3e-08 33.9 3.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KUM57364.1 - 4e-07 29.8 0.4 9.4e-07 28.6 0.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KUM57364.1 - 4.7e-05 23.3 1.3 0.00019 21.4 1.3 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KUM57364.1 - 6e-05 22.8 3.2 6e-05 22.8 3.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KUM57364.1 - 6e-05 22.6 1.0 0.00013 21.5 1.0 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KUM57364.1 - 8.1e-05 22.4 6.0 0.00023 20.9 2.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KUM57364.1 - 0.00016 21.6 2.7 0.00049 20.0 0.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KUM57364.1 - 0.0048 16.9 2.4 0.065 13.3 1.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KUM57364.1 - 0.014 15.3 2.8 0.014 15.3 2.8 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KUM57364.1 - 0.036 14.2 1.1 0.072 13.3 1.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Exonuc_VII_L PF02601.15 KUM57364.1 - 0.2 11.2 1.8 0.39 10.2 1.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_Mu_Gam PF07352.12 KUM57364.1 - 0.33 10.9 3.6 2.5 8.0 0.5 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein zf-RING-like PF08746.11 KUM57364.1 - 0.33 11.3 2.3 0.64 10.4 2.3 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_11 PF17123.5 KUM57364.1 - 0.53 10.1 3.9 0.51 10.1 0.3 2.3 2 0 0 2 2 2 0 RING-like zinc finger CopD PF05425.13 KUM57364.1 - 1.1 9.7 8.0 0.34 11.3 4.1 2.2 2 0 0 2 2 2 0 Copper resistance protein D zf-RING_4 PF14570.6 KUM57364.1 - 3.5 7.5 4.4 1.4 8.8 1.6 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Tim17 PF02466.19 KUM57365.1 - 5.9e-13 49.2 0.8 9.6e-13 48.5 0.4 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Pox_A6 PF04924.12 KUM57365.1 - 0.13 11.2 0.0 0.17 10.8 0.0 1.0 1 0 0 1 1 1 0 Poxvirus A6 protein Hamartin PF04388.12 KUM57366.1 - 0.11 11.1 17.6 0.13 11.0 17.6 1.1 1 0 0 1 1 1 0 Hamartin protein SOG2 PF10428.9 KUM57366.1 - 6.2 5.9 18.2 7.1 5.7 18.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CytochromB561_N PF09786.9 KUM57366.1 - 9.5 5.1 12.1 11 4.9 12.1 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal MFS_1 PF07690.16 KUM57367.1 - 3.8e-12 45.8 16.0 4.6e-12 45.5 3.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 KUM57367.1 - 0.00038 19.2 0.4 0.18 10.4 0.1 2.3 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like DUF1772 PF08592.11 KUM57367.1 - 0.0051 17.1 1.9 1.6 9.0 1.2 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF1772) Nucleoside_tran PF01733.18 KUM57367.1 - 0.011 15.1 0.0 0.011 15.1 0.0 1.8 3 0 0 3 3 3 0 Nucleoside transporter Otopetrin PF03189.13 KUM57367.1 - 0.027 13.3 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Otopetrin MFS_1_like PF12832.7 KUM57367.1 - 0.034 13.0 0.1 0.034 13.0 0.1 2.1 3 0 0 3 3 3 0 MFS_1 like family SUR7 PF06687.12 KUM57367.1 - 0.036 13.7 0.3 0.19 11.3 0.1 2.2 2 0 0 2 2 2 0 SUR7/PalI family DUF485 PF04341.12 KUM57367.1 - 0.041 13.8 0.2 0.041 13.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF485 ATP-synt_I PF03899.15 KUM57367.1 - 0.043 14.2 0.4 0.043 14.2 0.4 3.1 3 0 0 3 3 3 0 ATP synthase I chain MFS_2 PF13347.6 KUM57367.1 - 0.61 8.6 12.1 0.098 11.2 0.8 2.6 3 0 0 3 3 3 0 MFS/sugar transport protein DUF2206 PF09971.9 KUM57367.1 - 5.6 5.6 6.3 0.42 9.3 1.5 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) ADH_N PF08240.12 KUM57369.1 - 5.9e-17 61.5 4.0 9.3e-17 60.9 4.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 KUM57369.1 - 5.1e-06 26.0 0.0 7.8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KUM57369.1 - 9.4e-06 25.6 0.0 1.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KUM57369.1 - 0.001 18.4 0.0 0.0025 17.2 0.0 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KUM57369.1 - 0.036 14.1 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KUM57369.1 - 0.087 12.7 0.4 0.13 12.1 0.3 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATPgrasp_N PF18130.1 KUM57369.1 - 0.18 12.4 0.0 0.4 11.3 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp N-terminal domain adh_short PF00106.25 KUM57370.1 - 1.1e-26 93.6 0.7 1.5e-26 93.1 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM57370.1 - 5.4e-20 72.0 1.6 6.5e-20 71.7 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM57370.1 - 7.1e-08 32.6 0.2 9e-08 32.2 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KUM57370.1 - 3.8e-05 23.7 0.4 4.7e-05 23.4 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KUM57370.1 - 0.023 14.1 0.4 0.081 12.3 0.4 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase TFIIF_alpha PF05793.12 KUM57371.1 - 0.05 12.2 5.5 0.059 12.0 5.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1365 PF07103.11 KUM57372.1 - 8.5e-27 94.3 0.0 1.4e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) DUF3431 PF11913.8 KUM57373.1 - 3.7e-90 301.4 0.0 4.7e-90 301.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) SQHop_cyclase_C PF13243.6 KUM57375.1 - 9.5e-20 70.9 0.0 1e-19 70.8 0.0 1.0 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KUM57375.1 - 1.5e-09 37.5 0.9 5.3e-09 35.7 0.3 2.2 2 1 0 2 2 2 1 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KUM57375.1 - 0.00028 20.0 0.0 0.0047 16.0 0.0 1.8 1 1 1 2 2 2 1 A-macroglobulin TED domain Pec_lyase PF09492.10 KUM57375.1 - 0.0051 16.2 0.0 0.016 14.6 0.0 1.7 1 1 0 1 1 1 1 Pectic acid lyase SQHop_cyclase_N PF13249.6 KUM57375.1 - 0.0079 15.3 0.1 0.38 9.8 0.1 2.0 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain MFS_1 PF07690.16 KUM57376.1 - 2.7e-24 85.7 42.8 2.7e-24 85.7 42.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KUM57378.1 - 3.4e-18 65.7 0.0 1.9e-17 63.2 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM57378.1 - 2.2e-07 30.9 13.1 3.5e-07 30.2 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.15 KUM57379.1 - 3.8e-35 122.2 0.0 6.6e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KUM57379.1 - 2.4e-18 66.7 0.5 1.6e-17 64.1 0.0 2.3 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.11 KUM57379.1 - 1.3e-13 51.0 0.0 3.1e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 KUM57379.1 - 1.2e-08 35.1 0.0 2.8e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 KUM57379.1 - 1.5e-05 24.6 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain F420_oxidored PF03807.17 KUM57379.1 - 0.0092 16.5 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 KUM57380.1 - 3.9e-16 58.9 58.0 3.2e-08 32.9 27.5 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM57380.1 - 1.3e-05 23.8 15.2 1.3e-05 23.8 15.2 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Arg_repressor PF01316.21 KUM57380.1 - 0.15 11.9 0.1 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Methyltransf_2 PF00891.18 KUM57381.1 - 5.9e-12 45.3 0.0 1.6e-11 43.9 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KUM57381.1 - 0.018 14.9 0.1 0.072 12.9 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Dimerisation PF08100.11 KUM57381.1 - 0.15 12.1 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Fringe PF02434.16 KUM57383.1 - 2.1e-05 24.1 0.9 0.001 18.5 0.2 2.9 2 1 0 2 2 2 1 Fringe-like PAN_1 PF00024.26 KUM57383.1 - 0.00013 21.8 0.2 0.00027 20.8 0.2 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 KUM57383.1 - 0.01 15.7 0.3 0.026 14.5 0.3 1.6 1 0 0 1 1 1 0 PAN domain CarbpepA_inh PF02977.15 KUM57383.1 - 0.12 12.2 0.6 0.28 11.0 0.6 1.5 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor Galactosyl_T PF01762.21 KUM57383.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Galactosyltransferase Glyco_transf_34 PF05637.12 KUM57383.1 - 0.82 9.4 2.8 1.4 8.6 2.8 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family SQHop_cyclase_N PF13249.6 KUM57384.1 - 2.8e-32 112.0 2.4 4.3e-32 111.4 2.4 1.3 1 0 0 1 1 1 1 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KUM57384.1 - 2.8e-08 33.3 0.0 6.6e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Prenyltransferase and squalene oxidase repeat DUF2235 PF09994.9 KUM57385.1 - 8.6e-84 281.3 0.0 1.1e-83 280.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) RGI_lyase PF18370.1 KUM57385.1 - 0.17 12.2 0.4 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 Rhamnogalacturonan I lyases beta-sheet domain Methyltransf_25 PF13649.6 KUM57386.1 - 4.3e-13 49.8 0.0 7.1e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM57386.1 - 1.6e-11 44.7 0.1 2.5e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM57386.1 - 2.3e-09 37.2 0.0 3.7e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM57386.1 - 2.2e-07 31.5 0.0 3.3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM57386.1 - 4.8e-07 29.7 0.0 6.2e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM57386.1 - 0.00013 21.4 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KUM57386.1 - 0.00044 19.7 0.6 0.00074 19.0 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KUM57386.1 - 0.00052 19.6 0.0 0.00078 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KUM57386.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW N6_N4_Mtase PF01555.18 KUM57386.1 - 0.035 13.8 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 DNA methylase Methyltransf_16 PF10294.9 KUM57386.1 - 0.083 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase MFS_1 PF07690.16 KUM57387.1 - 1.3e-35 123.0 54.6 3.3e-35 121.7 54.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM57387.1 - 4e-13 48.7 27.0 7.8e-13 47.7 27.0 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM57387.1 - 1.7e-12 47.0 11.9 1.7e-12 47.0 11.9 3.5 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3522 PF12036.8 KUM57387.1 - 0.004 17.5 0.3 0.004 17.5 0.3 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF3522) DUF3937 PF13073.6 KUM57387.1 - 0.13 12.4 2.7 0.2 11.8 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3937) Pox_A14 PF05767.12 KUM57387.1 - 0.17 12.1 0.1 0.17 12.1 0.1 3.0 4 1 0 4 4 4 0 Poxvirus virion envelope protein A14 Asparaginase_II PF06089.12 KUM57388.1 - 3.2e-114 381.3 0.3 3.6e-114 381.1 0.3 1.0 1 0 0 1 1 1 1 L-asparaginase II Glyco_hydro_3_C PF01915.22 KUM57389.1 - 1.5e-57 194.8 0.0 2.3e-57 194.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KUM57389.1 - 3e-39 135.3 0.0 6.5e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KUM57389.1 - 1.2e-25 89.4 0.0 2.7e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KUM57389.1 - 4.8e-15 55.6 0.0 9.1e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Questin_oxidase PF14027.6 KUM57390.1 - 4.2e-11 43.0 0.1 6.2e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Questin oxidase-like ADH_N PF08240.12 KUM57391.1 - 1.7e-19 69.7 2.8 3.1e-17 62.4 2.8 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain F_actin_bind PF08919.10 KUM57393.1 - 0.18 11.9 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 F-actin binding Sugar_tr PF00083.24 KUM57394.1 - 4.6e-76 256.5 22.4 5.5e-76 256.2 22.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM57394.1 - 1.9e-21 76.4 18.9 1.9e-21 76.4 18.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily COX7C PF02935.16 KUM57394.1 - 0.2 12.0 1.1 14 6.0 0.5 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Response_reg PF00072.24 KUM57395.1 - 8.8e-19 67.7 0.1 2.1e-18 66.5 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KUM57395.1 - 4.1e-18 65.9 0.0 9.2e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KUM57395.1 - 1.1e-10 41.4 0.1 4.2e-10 39.5 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 KUM57395.1 - 0.00052 20.7 0.0 0.0017 19.0 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KUM57395.1 - 0.037 14.4 0.0 0.37 11.1 0.0 2.7 2 0 0 2 2 2 0 GAF domain Git3 PF11710.8 KUM57396.1 - 1.9e-18 67.0 20.8 3.7e-18 66.0 20.8 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KUM57396.1 - 3.3e-09 36.7 0.0 3.3e-09 36.7 0.0 2.8 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF2207 PF09972.9 KUM57396.1 - 0.14 10.9 0.0 0.14 10.9 0.0 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Ank_2 PF12796.7 KUM57397.1 - 3.2e-60 200.7 14.2 1.1e-14 54.8 0.3 12.6 7 4 6 13 13 13 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM57397.1 - 1.1e-49 166.2 24.3 1.6e-06 28.6 0.0 19.4 13 7 8 21 21 21 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM57397.1 - 3.3e-44 148.4 31.5 2.8e-08 33.8 0.1 17.4 16 4 3 19 19 19 11 Ankyrin repeats (many copies) Ank PF00023.30 KUM57397.1 - 9.9e-44 145.9 30.4 4.1e-08 33.3 0.0 19.4 22 0 0 22 22 22 11 Ankyrin repeat Ank_3 PF13606.6 KUM57397.1 - 1.8e-32 107.7 31.4 4.2e-07 29.8 0.0 19.4 23 0 0 23 23 23 8 Ankyrin repeat DUF3292 PF11696.8 KUM57398.1 - 3e-229 762.7 0.0 3.4e-229 762.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) DUF2182 PF09948.9 KUM57398.1 - 0.065 13.1 0.3 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) EBP PF05241.12 KUM57400.1 - 2e-66 222.8 6.4 2.4e-66 222.6 6.4 1.0 1 0 0 1 1 1 1 Emopamil binding protein SesA PF17107.5 KUM57401.1 - 2.8e-05 24.3 0.0 5.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Leader_CPA1 PF08252.11 KUM57401.1 - 0.011 15.1 2.9 0.47 9.9 1.7 2.6 2 0 0 2 2 2 0 arg-2/CPA1 leader peptide Sec34 PF04136.15 KUM57401.1 - 0.13 12.2 0.3 5.7 6.8 0.1 2.6 2 0 0 2 2 2 0 Sec34-like family FliD_N PF02465.18 KUM57401.1 - 0.56 10.9 2.9 2.5 8.9 0.2 2.9 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Mito_carr PF00153.27 KUM57403.1 - 8.8e-47 157.0 1.0 4.8e-16 58.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF346 PF03984.13 KUM57403.1 - 1.6 8.5 6.0 0.66 9.8 3.3 1.8 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) MFS_1 PF07690.16 KUM57405.1 - 2.4e-37 128.7 26.0 4e-37 127.9 16.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KUM57405.1 - 6.8e-06 24.7 0.7 4.8e-05 21.8 0.7 2.0 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 KUM57405.1 - 0.0039 15.8 15.0 0.11 11.0 0.8 3.3 2 2 1 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.7 KUM57405.1 - 0.0072 15.2 13.2 0.068 12.0 6.6 3.1 1 1 2 3 3 3 2 MFS_1 like family SmaI PF17411.2 KUM57406.1 - 0.13 11.4 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease Zn_clus PF00172.18 KUM57407.1 - 8.3e-06 25.8 7.2 8.3e-06 25.8 7.2 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM57407.1 - 0.028 13.3 0.0 0.043 12.6 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain MspA PF09203.11 KUM57408.1 - 0.57 10.0 4.2 0.49 10.2 1.4 2.3 2 1 0 2 2 2 0 MspA Abhydrolase_4 PF08386.10 KUM57409.1 - 7.9e-16 58.0 0.0 4.2e-15 55.7 0.0 2.0 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 KUM57409.1 - 7.9e-14 51.9 0.0 1.4e-11 44.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM57409.1 - 0.13 11.6 0.0 5.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 AMP-binding PF00501.28 KUM57410.1 - 0 1074.2 0.0 3.8e-70 236.6 0.0 5.2 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.20 KUM57410.1 - 4.5e-183 609.1 0.0 4.6e-38 131.1 0.0 5.7 5 1 0 5 5 5 5 Condensation domain PP-binding PF00550.25 KUM57410.1 - 2.1e-49 165.7 7.3 2.5e-10 40.5 0.0 6.0 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM57410.1 - 1e-10 42.4 0.0 0.031 15.3 0.0 5.8 5 0 0 5 5 5 2 AMP-binding enzyme C-terminal domain DIOX_N PF14226.6 KUM57411.1 - 2e-22 80.2 0.0 3.8e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KUM57411.1 - 1.2e-13 51.4 0.0 2.3e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CdvA PF18822.1 KUM57412.1 - 0.33 10.8 2.3 0.21 11.4 0.3 1.7 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Myb_DNA-bind_5 PF13873.6 KUM57413.1 - 0.019 15.0 1.8 0.24 11.5 0.5 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 KUM57413.1 - 0.097 12.9 0.3 0.18 12.0 0.3 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain GIT_CC PF16559.5 KUM57414.1 - 0.0071 16.2 0.7 0.013 15.4 0.7 1.6 1 1 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor MAP70 PF07058.11 KUM57414.1 - 0.013 14.2 0.1 0.02 13.6 0.1 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 HemX PF04375.14 KUM57414.1 - 0.026 13.8 0.9 0.035 13.4 0.9 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Ssu72 PF04722.13 KUM57414.1 - 0.099 12.2 0.2 0.15 11.6 0.2 1.3 1 1 0 1 1 1 0 Ssu72-like protein DivIC PF04977.15 KUM57414.1 - 0.15 11.9 1.2 0.25 11.1 0.3 1.8 1 1 1 2 2 2 0 Septum formation initiator DUF3972 PF13118.6 KUM57414.1 - 0.15 12.5 1.0 0.67 10.4 1.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) TolA_bind_tri PF16331.5 KUM57414.1 - 0.23 11.5 4.3 0.57 10.3 2.6 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation SlyX PF04102.12 KUM57414.1 - 0.78 10.4 2.9 3.4 8.4 0.8 2.3 1 1 1 2 2 2 0 SlyX FMO-like PF00743.19 KUM57415.1 - 8.2e-13 47.6 0.0 3.2e-10 39.0 0.0 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KUM57415.1 - 1e-10 41.4 0.0 1.5e-07 30.9 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM57415.1 - 1.1e-09 38.3 0.0 4e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KUM57415.1 - 1.9e-07 30.6 0.0 0.00033 20.0 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM57415.1 - 4.2e-07 29.4 0.0 0.0012 18.1 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KUM57415.1 - 2.9e-05 24.1 0.3 0.00086 19.3 0.0 3.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KUM57415.1 - 0.00033 21.2 0.0 0.92 10.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM57415.1 - 0.12 11.9 0.0 0.93 9.0 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KUM57415.1 - 0.15 11.3 0.1 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TPR_12 PF13424.6 KUM57416.1 - 1.2e-23 83.2 5.0 3.3e-19 69.0 0.4 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KUM57416.1 - 1.8e-22 78.5 7.3 5.8e-10 38.7 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KUM57416.1 - 3.2e-08 33.1 3.7 0.012 15.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KUM57416.1 - 1.1e-07 31.4 6.9 0.014 15.3 0.1 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KUM57416.1 - 2.8e-07 30.8 2.4 0.25 12.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KUM57416.1 - 3.7e-05 23.3 0.6 6e-05 22.6 0.6 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_2 PF07719.17 KUM57416.1 - 6.7e-05 22.7 3.5 0.52 10.6 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KUM57416.1 - 8.6e-05 22.5 1.2 2 8.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF676 PF05057.14 KUM57416.1 - 0.00013 21.5 0.1 0.00051 19.6 0.1 1.8 1 1 1 2 2 2 1 Putative serine esterase (DUF676) NB-ARC PF00931.22 KUM57416.1 - 0.00016 20.9 0.0 0.0003 20.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ANAPC3 PF12895.7 KUM57416.1 - 0.00094 19.4 0.2 0.33 11.2 0.1 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KUM57416.1 - 0.0026 18.2 0.0 2.4 9.0 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.6 KUM57416.1 - 0.0083 16.5 2.3 0.052 13.9 0.9 3.0 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KUM57416.1 - 0.011 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Abhydrolase_6 PF12697.7 KUM57416.1 - 0.011 16.3 0.0 0.064 13.8 0.0 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family TPR_19 PF14559.6 KUM57416.1 - 0.028 14.9 0.2 0.16 12.5 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KUM57416.1 - 0.032 14.9 10.4 1.2 9.8 0.3 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 KUM57416.1 - 0.1 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 NRBF2_MIT PF17169.4 KUM57416.1 - 0.11 12.7 1.5 1.4 9.2 0.5 2.8 2 1 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 zf-RVT PF13966.6 KUM57417.1 - 0.02 15.6 0.1 0.038 14.7 0.1 1.5 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase DUF4722 PF15849.5 KUM57417.1 - 0.028 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4722) RNase_H PF00075.24 KUM57417.1 - 0.19 11.9 0.2 0.36 11.0 0.2 1.5 1 0 0 1 1 1 0 RNase H DUF3435 PF11917.8 KUM57419.1 - 2.2e-22 79.6 0.0 3.5e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.22 KUM57419.1 - 0.028 14.2 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Phage integrase family SBP PF03110.14 KUM57419.1 - 8.8 6.7 10.2 3.2 8.1 6.0 2.6 2 0 0 2 2 2 0 SBP domain BTB PF00651.31 KUM57421.1 - 2.3e-13 50.3 0.2 2.5e-12 47.0 0.1 2.4 3 0 0 3 3 3 1 BTB/POZ domain C1_1 PF00130.22 KUM57421.1 - 0.047 13.6 0.9 0.047 13.6 0.9 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Nudix_N_2 PF14803.6 KUM57421.1 - 0.43 10.5 5.0 12 5.9 3.0 3.0 2 2 0 2 2 2 0 Nudix N-terminal zinc_ribbon_10 PF10058.9 KUM57421.1 - 2.1 8.1 5.9 1.7 8.4 3.0 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein HTH_33 PF13592.6 KUM57423.1 - 9.7e-07 28.3 0.1 2.7e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix DDE_3 PF13358.6 KUM57423.1 - 0.00021 21.1 0.0 0.007 16.1 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KUM57423.1 - 0.022 15.4 0.0 0.25 12.0 0.0 2.3 1 1 1 2 2 2 0 Homeodomain-like domain Dynamin_N PF00350.23 KUM57424.1 - 1.9e-37 128.9 0.0 4.1e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KUM57424.1 - 2.9e-20 72.7 0.0 5.5e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KUM57424.1 - 5.8e-05 23.1 0.0 0.00019 21.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Med9 PF07544.13 KUM57424.1 - 0.0092 16.1 1.7 0.024 14.7 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 AviRa PF11599.8 KUM57424.1 - 0.057 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 RRNA methyltransferase AviRa AAA_29 PF13555.6 KUM57424.1 - 0.1 12.3 0.2 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_15 PF13175.6 KUM57424.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Beta-lactamase PF00144.24 KUM57425.1 - 5e-37 127.9 0.0 8.9e-37 127.1 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KUM57425.1 - 1.2e-11 45.0 0.0 2.2e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) SnoaL_4 PF13577.6 KUM57426.1 - 5.7e-20 71.7 0.0 8.1e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Amidohydro_1 PF01979.20 KUM57428.1 - 1.2e-31 110.4 0.0 2.1e-31 109.5 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KUM57428.1 - 2.1e-13 50.6 3.6 7.7e-08 32.2 0.4 2.2 2 0 0 2 2 2 2 Amidohydrolase family Aldose_epim PF01263.20 KUM57429.1 - 4.8e-49 167.3 0.4 6.3e-49 166.9 0.4 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Cupin_2 PF07883.11 KUM57429.1 - 0.02 14.6 0.1 0.069 12.9 0.0 1.9 2 0 0 2 2 2 0 Cupin domain Cyt-b5 PF00173.28 KUM57430.1 - 1.2e-16 60.6 0.0 2.2e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 KUM57430.1 - 1.8e-16 60.8 17.0 1.8e-16 60.8 17.0 1.7 2 1 0 2 2 2 1 Fatty acid desaturase YndJ PF14158.6 KUM57430.1 - 0.01 15.2 1.8 0.017 14.5 1.8 1.2 1 0 0 1 1 1 0 YndJ-like protein AMP-binding PF00501.28 KUM57431.1 - 8.2e-56 189.4 0.0 9.9e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM57431.1 - 2.1e-12 47.8 0.0 7.6e-12 46.0 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACOX PF01756.19 KUM57432.1 - 1e-40 139.2 1.6 1.9e-40 138.3 0.3 2.0 3 0 0 3 3 3 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KUM57432.1 - 9.5e-26 90.8 1.3 1.8e-25 89.9 1.3 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KUM57432.1 - 9.3e-08 32.2 0.0 2.2e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KUM57432.1 - 0.0097 16.1 0.1 0.034 14.3 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2019 PF09450.10 KUM57432.1 - 0.08 12.9 0.0 0.26 11.2 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF2019) Fungal_trans PF04082.18 KUM57433.1 - 6.1e-15 55.0 0.0 9.3e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH_1 PF00378.20 KUM57434.1 - 3.4e-24 85.5 0.0 3.9e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KUM57434.1 - 3.6e-11 43.2 0.0 4.2e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase UDG PF03167.19 KUM57435.1 - 0.06 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily Glyco_hydro_16 PF00722.21 KUM57437.1 - 1.3e-10 41.0 0.0 4.8e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1388 PF07142.12 KUM57438.1 - 0.00082 19.3 6.4 0.00082 19.3 6.4 2.3 2 0 0 2 2 2 1 Repeat of unknown function (DUF1388) EMP24_GP25L PF01105.24 KUM57439.1 - 3.3e-51 173.8 1.2 3.9e-51 173.6 1.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SANT_DAMP1_like PF16282.5 KUM57440.1 - 2.6e-30 104.5 2.0 4.6e-30 103.6 2.0 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 KUM57440.1 - 0.00011 22.1 14.5 0.013 15.4 14.3 3.3 1 1 1 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.6 KUM57440.1 - 0.011 15.9 0.0 0.039 14.2 0.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KUM57440.1 - 0.1 12.8 0.0 0.43 10.8 0.0 2.2 1 1 0 1 1 1 0 Myb-like DNA-binding domain HATPase_c PF02518.26 KUM57442.1 - 1.3e-21 77.2 0.0 3e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KUM57442.1 - 3.7e-16 59.3 0.4 9e-09 35.5 0.8 3.6 2 1 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 KUM57442.1 - 0.00021 21.2 0.0 0.00079 19.4 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain TUG-UBL1 PF11470.8 KUM57443.1 - 3.4e-24 84.9 0.1 8.2e-24 83.6 0.1 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 KUM57443.1 - 0.00036 20.7 0.0 0.0017 18.5 0.0 2.2 2 0 0 2 2 2 1 UBX domain RBD PF02196.15 KUM57443.1 - 0.13 12.4 0.0 0.87 9.7 0.0 2.3 3 0 0 3 3 3 0 Raf-like Ras-binding domain EHN PF06441.12 KUM57444.1 - 1.1e-16 61.1 2.1 2.7e-15 56.6 0.3 2.4 2 0 0 2 2 2 2 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KUM57444.1 - 0.0018 18.0 0.0 0.006 16.3 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Proteasome PF00227.26 KUM57445.1 - 1.4e-41 142.1 0.0 1.6e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit LIP PF03583.14 KUM57446.1 - 2.8e-09 36.7 2.0 2.3e-08 33.7 2.0 2.0 1 1 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 KUM57446.1 - 1.1e-05 24.9 0.6 6.6e-05 22.3 0.4 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KUM57446.1 - 2.3e-05 25.1 1.7 3.3e-05 24.6 1.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KUM57446.1 - 2.5e-05 23.9 0.2 0.011 15.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF3405 PF11885.8 KUM57447.1 - 1.8e-232 772.5 0.3 2.2e-232 772.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) FMO-like PF00743.19 KUM57448.1 - 9.5e-14 50.7 0.0 1.6e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KUM57448.1 - 4.5e-11 42.5 0.1 4.7e-09 35.9 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM57448.1 - 1.8e-08 34.5 0.0 8.3e-08 32.4 0.0 2.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KUM57448.1 - 5.8e-07 29.7 0.1 8.1e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KUM57448.1 - 1.1e-06 28.1 0.3 0.00044 19.6 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM57448.1 - 5.2e-05 22.5 0.4 0.0073 15.5 0.2 3.1 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KUM57448.1 - 0.004 17.7 0.1 0.72 10.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM57448.1 - 0.0088 15.7 0.0 1.9 8.0 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KUM57448.1 - 0.055 12.7 0.0 0.61 9.3 0.0 2.0 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 KUM57448.1 - 0.069 12.2 0.1 0.34 10.0 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KUM57448.1 - 0.086 11.5 0.4 0.47 9.1 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 KUM57448.1 - 0.17 11.1 0.1 0.17 11.1 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain zf-RING_5 PF14634.6 KUM57449.1 - 0.0081 16.1 6.4 0.028 14.4 6.5 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KUM57449.1 - 0.011 15.6 6.1 0.057 13.3 6.0 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KUM57449.1 - 0.021 14.7 5.6 0.049 13.5 5.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KUM57449.1 - 1.2 9.1 10.0 13 5.7 10.1 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KUM57449.1 - 1.3 9.2 6.4 0.8 9.9 2.5 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KUM57449.1 - 1.4 9.0 8.8 1.4 9.0 4.7 2.8 1 1 1 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KUM57449.1 - 2.3 8.1 8.1 1.6 8.7 5.6 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KUM57449.1 - 5.4 7.4 11.4 90 3.5 12.1 2.5 1 1 1 2 2 2 0 Ring finger domain Asp PF00026.23 KUM57450.1 - 2.7e-06 27.0 0.0 5.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.10 KUM57450.1 - 0.0026 17.1 0.7 0.0055 16.1 0.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CcmD PF04995.14 KUM57450.1 - 0.26 11.4 1.0 0.53 10.4 1.0 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) IMUP PF15761.5 KUM57450.1 - 1 10.1 5.0 2.2 9.0 5.0 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein TauD PF02668.16 KUM57451.1 - 2.4e-34 119.3 0.2 3.7e-34 118.7 0.2 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KUM57451.1 - 0.053 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 CsiD DUF1449 PF07290.11 KUM57452.1 - 0.036 13.7 0.1 0.036 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) MFS_1 PF07690.16 KUM57452.1 - 0.048 12.6 0.0 0.06 12.3 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Phage_HK97_TLTM PF06120.11 KUM57453.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Tail length tape measure protein SieB PF14163.6 KUM57454.1 - 0.0031 17.0 4.0 0.0033 16.9 2.7 1.7 1 1 0 1 1 1 1 Super-infection exclusion protein B CorA PF01544.18 KUM57454.1 - 0.021 14.2 1.0 0.033 13.5 1.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PufQ PF05398.11 KUM57454.1 - 0.04 14.1 1.7 4.7 7.4 0.0 2.4 1 1 1 2 2 2 0 PufQ cytochrome subunit DUF1361 PF07099.11 KUM57454.1 - 0.047 13.7 6.3 0.07 13.1 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1361) Arf PF00025.21 KUM57455.1 - 7.7e-79 263.2 0.1 8.9e-79 263.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KUM57455.1 - 6.3e-15 55.1 0.0 7.7e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KUM57455.1 - 3.1e-14 53.2 0.0 4.3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KUM57455.1 - 3.6e-13 49.4 1.2 2.1e-09 37.1 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KUM57455.1 - 4.8e-13 49.0 0.0 5.3e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KUM57455.1 - 2.2e-10 40.3 0.0 2.6e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KUM57455.1 - 4.3e-06 26.8 0.0 6.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KUM57455.1 - 0.012 14.9 0.4 0.027 13.8 0.4 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Exo84_C PF16528.5 KUM57457.1 - 0.22 11.3 0.5 0.35 10.7 0.5 1.2 1 0 0 1 1 1 0 Exocyst component 84 C-terminal Ribosomal_L1 PF00687.21 KUM57458.1 - 2.4e-45 154.8 0.6 3.3e-45 154.4 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DEK_C PF08766.11 KUM57458.1 - 0.11 12.4 0.7 0.32 11.0 0.1 2.0 2 0 0 2 2 2 0 DEK C terminal domain MFS_1 PF07690.16 KUM57459.1 - 1.3e-17 63.8 14.7 1.3e-17 63.8 14.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2142 PF09913.9 KUM57459.1 - 0.0082 15.1 5.1 0.0073 15.2 3.6 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2142) DUF2530 PF10745.9 KUM57459.1 - 0.01 16.1 1.7 0.01 16.1 1.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Fic PF02661.18 KUM57461.1 - 7.2e-17 62.1 0.1 4.4e-16 59.6 0.0 2.4 2 1 0 2 2 2 1 Fic/DOC family Bromodomain PF00439.25 KUM57463.1 - 5.2e-15 55.3 0.0 9.4e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DUF3844 PF12955.7 KUM57464.1 - 2.8e-34 117.4 5.8 4.5e-34 116.7 5.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) zf-RING_2 PF13639.6 KUM57465.1 - 4.3e-12 46.2 6.5 6.7e-12 45.6 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KUM57465.1 - 7.4e-09 35.3 5.6 1.2e-08 34.6 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KUM57465.1 - 1.4e-08 34.3 1.9 2.4e-08 33.6 1.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KUM57465.1 - 1.4e-07 31.3 3.9 2.2e-07 30.6 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KUM57465.1 - 3.2e-06 27.0 3.2 5.1e-06 26.3 3.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KUM57465.1 - 6e-06 26.5 9.8 2.6e-05 24.4 9.8 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KUM57465.1 - 0.00037 20.4 0.8 0.00037 20.4 0.8 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KUM57465.1 - 0.0019 18.2 2.7 0.0052 16.8 2.7 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KUM57465.1 - 0.0027 17.5 2.7 0.0047 16.8 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KUM57465.1 - 0.0093 15.6 3.3 0.016 14.8 3.3 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KUM57465.1 - 0.098 12.5 6.6 0.17 11.7 6.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KUM57465.1 - 0.15 12.0 5.5 0.32 10.9 5.5 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 KUM57465.1 - 0.15 12.2 4.8 0.32 11.2 4.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING OAD_gamma PF04277.13 KUM57465.1 - 0.19 12.3 0.0 0.59 10.8 0.0 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Prok-RING_4 PF14447.6 KUM57465.1 - 0.29 11.0 5.8 0.78 9.7 5.8 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 KUM57465.1 - 0.42 10.7 3.3 1.1 9.3 3.3 1.7 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 KUM57465.1 - 0.6 10.3 4.0 1.3 9.2 4.0 1.6 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KUM57465.1 - 0.83 9.9 3.6 2.3 8.4 3.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain HSP70 PF00012.20 KUM57468.1 - 1.9e-222 739.7 6.8 2.1e-222 739.6 6.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KUM57468.1 - 2.2e-16 59.6 0.5 8e-16 57.8 0.1 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KUM57468.1 - 0.00041 20.1 0.0 0.00091 19.0 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain HEPPP_synt_1 PF07307.11 KUM57468.1 - 0.15 11.6 0.2 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 NAF PF03822.14 KUM57468.1 - 0.26 11.5 1.0 2.3 8.4 0.1 2.5 2 0 0 2 2 2 0 NAF domain Zn_clus PF00172.18 KUM57469.1 - 3.6e-06 27.0 8.5 6.4e-06 26.2 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM57469.1 - 1.5e-05 24.2 0.2 2.9e-05 23.2 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain tRNA-synt_2c PF01411.19 KUM57470.1 - 1.9e-217 723.2 0.0 3.2e-217 722.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KUM57470.1 - 2.8e-17 62.6 0.5 6.1e-17 61.4 0.5 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KUM57470.1 - 3.8e-10 40.3 2.0 3.8e-10 40.3 2.0 2.3 2 0 0 2 2 2 1 DHHA1 domain Pro_isomerase PF00160.21 KUM57471.1 - 2.2e-48 164.5 1.1 2.5e-48 164.4 1.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRF PF01765.19 KUM57472.1 - 2.3e-45 154.5 1.7 2.9e-45 154.1 1.7 1.1 1 0 0 1 1 1 1 Ribosome recycling factor PcfJ PF14284.6 KUM57472.1 - 0.046 13.6 1.6 0.077 12.9 1.6 1.4 1 0 0 1 1 1 0 PcfJ-like protein DUF3813 PF12758.7 KUM57472.1 - 5.1 7.5 8.7 7 7.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3813) CKS PF01111.19 KUM57473.1 - 3e-34 117.1 0.7 3e-34 117.1 0.7 1.8 3 0 0 3 3 3 1 Cyclin-dependent kinase regulatory subunit SPESP1 PF15754.5 KUM57474.1 - 0.023 13.9 0.0 0.033 13.4 0.0 1.1 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Nnf1 PF03980.14 KUM57475.1 - 0.0055 17.1 0.2 0.01 16.2 0.2 1.3 1 0 0 1 1 1 1 Nnf1 Erf4 PF10256.9 KUM57475.1 - 0.041 14.0 0.0 0.21 11.7 0.0 2.1 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family AMP-binding PF00501.28 KUM57477.1 - 6.8e-27 94.1 0.0 8.6e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 KUM57478.1 - 1.3e-47 162.4 0.0 1.6e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM57478.1 - 6.3e-12 46.3 0.0 1e-11 45.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 KUM57479.1 - 4.1e-15 55.5 0.1 9.1e-15 54.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM57479.1 - 1.4e-05 25.2 9.2 2.6e-05 24.3 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2655 PF10848.8 KUM57479.1 - 0.029 14.7 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2655) YL1 PF05764.13 KUM57480.1 - 0.0052 16.9 4.6 0.0052 16.9 4.6 2.2 2 0 0 2 2 2 1 YL1 nuclear protein FancD2 PF14631.6 KUM57480.1 - 1.5 6.1 5.5 2.2 5.5 5.5 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF1764 PF08576.10 KUM57480.1 - 6.6 7.7 11.6 0.49 11.3 5.2 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Sdh_cyt PF01127.22 KUM57481.1 - 0.23 11.5 1.0 0.34 10.9 1.0 1.2 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PMT PF02366.18 KUM57482.1 - 1.9e-87 292.9 16.6 3.2e-87 292.2 16.6 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KUM57482.1 - 9.4e-68 227.7 1.3 9.4e-68 227.7 1.3 2.9 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KUM57482.1 - 5.7e-22 78.5 0.1 9.7e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KUM57482.1 - 0.002 18.4 5.3 0.002 18.4 5.3 3.9 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MFS_1 PF07690.16 KUM57483.1 - 4.5e-31 108.1 33.7 4.5e-31 108.1 33.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KUM57483.1 - 1.5 8.6 9.3 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RNA_pol_L_2 PF13656.6 KUM57485.1 - 4e-25 87.4 0.0 7.8e-25 86.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KUM57485.1 - 8.4e-09 34.7 0.0 1.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain EF-hand_4 PF12763.7 KUM57486.1 - 1.5e-26 92.3 0.0 5.2e-14 52.1 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.11 KUM57486.1 - 2.3e-14 53.5 148.5 2.6e-06 27.7 42.2 6.8 5 1 1 6 6 6 4 Domain of unknown function (DUF1720) EF-hand_7 PF13499.6 KUM57486.1 - 0.0012 19.3 2.6 0.049 14.1 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KUM57486.1 - 0.046 13.3 0.0 0.96 9.1 0.0 2.6 2 0 0 2 2 2 0 EF hand HMG_box_2 PF09011.10 KUM57487.1 - 3.4e-12 46.8 1.6 1.5e-09 38.3 0.1 2.9 2 1 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 KUM57487.1 - 2.3e-09 37.5 10.2 3.3e-09 37.0 0.8 3.1 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_5 PF14887.6 KUM57487.1 - 0.001 19.0 0.0 0.0032 17.4 0.0 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DEAD PF00270.29 KUM57488.1 - 2.9e-48 163.9 0.0 2.3e-47 161.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM57488.1 - 5.2e-27 94.4 0.0 2.5e-26 92.2 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain T5orf172 PF10544.9 KUM57488.1 - 0.093 13.3 1.2 0.35 11.4 1.2 2.0 1 0 0 1 1 1 0 T5orf172 domain WLM PF08325.10 KUM57489.1 - 0.52 10.4 2.5 0.27 11.3 0.2 1.6 2 0 0 2 2 2 0 WLM domain MerC PF03203.14 KUM57490.1 - 0.051 14.0 9.3 5.4 7.5 0.4 3.4 3 0 0 3 3 3 0 MerC mercury resistance protein UPF0016 PF01169.19 KUM57490.1 - 0.93 9.9 10.5 0.076 13.4 1.7 3.5 4 1 0 4 4 4 0 Uncharacterized protein family UPF0016 DUF1071 PF06378.11 KUM57491.1 - 0.039 13.5 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) DUF3134 PF11332.8 KUM57491.1 - 0.13 12.6 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) Dynamin_N PF00350.23 KUM57492.1 - 3e-30 105.5 0.1 7.3e-30 104.2 0.1 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KUM57492.1 - 9e-21 74.3 0.0 2.2e-15 56.7 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KUM57492.1 - 0.0048 17.0 0.2 0.035 14.2 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KUM57492.1 - 0.09 13.1 0.2 0.45 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AIG1 PF04548.16 KUM57492.1 - 0.44 9.8 2.0 2.4 7.4 0.0 2.9 3 0 0 3 3 3 0 AIG1 family GED PF02212.18 KUM57492.1 - 0.58 10.3 2.8 1.1 9.5 0.0 2.9 3 1 0 3 3 3 0 Dynamin GTPase effector domain EPV_E5 PF08135.11 KUM57493.1 - 0.049 14.0 5.1 0.071 13.5 5.1 1.2 1 0 0 1 1 1 0 Major transforming protein E5 family zf-C2H2 PF00096.26 KUM57495.1 - 3.4e-22 77.6 38.9 5.4e-06 26.6 4.4 8.3 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KUM57495.1 - 1.3e-15 57.0 35.6 3.2e-07 30.5 2.2 7.3 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KUM57495.1 - 3.9e-14 52.1 39.5 0.00027 21.5 3.0 8.7 7 0 0 7 7 7 4 C2H2-type zinc finger zf-met PF12874.7 KUM57495.1 - 4.8e-06 26.8 17.5 0.0063 16.9 0.1 5.5 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KUM57495.1 - 2e-05 24.8 19.1 0.0026 18.0 0.1 5.6 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KUM57495.1 - 0.051 13.6 0.4 0.051 13.6 0.4 5.6 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KUM57495.1 - 2.6 7.9 22.9 2.8 7.8 0.1 5.2 5 0 0 5 5 5 0 zinc-finger C2H2-type Spc7 PF08317.11 KUM57496.1 - 0.046 12.6 0.9 0.059 12.3 0.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FCD PF07729.12 KUM57496.1 - 0.13 12.7 2.7 0.29 11.6 0.3 2.3 2 0 0 2 2 2 0 FCD domain Trypan_PARP PF05887.11 KUM57497.1 - 0.0041 17.1 39.0 0.0041 17.1 39.0 14.7 4 2 9 14 14 14 5 Procyclic acidic repetitive protein (PARP) Mito_fiss_reg PF05308.11 KUM57497.1 - 0.074 13.1 0.0 0.074 13.1 0.0 12.8 6 2 7 13 13 13 0 Mitochondrial fission regulator EPL1 PF10513.9 KUM57498.1 - 3.4e-31 108.8 0.0 1.3e-30 106.8 0.0 2.0 1 1 0 1 1 1 1 Enhancer of polycomb-like zf-HC5HC2H_2 PF13832.6 KUM57498.1 - 1.3e-30 105.8 5.0 1.3e-30 105.8 5.0 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KUM57498.1 - 4.1e-26 91.0 1.7 4.1e-26 91.0 1.7 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KUM57498.1 - 5e-15 54.8 8.4 7.8e-14 50.9 2.3 2.6 2 0 0 2 2 2 2 PHD-finger PHD PF00628.29 KUM57498.1 - 3.4e-10 39.7 20.0 7.5e-09 35.4 9.5 2.6 2 0 0 2 2 2 2 PHD-finger Bromodomain PF00439.25 KUM57498.1 - 0.082 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Bromodomain zf-RING-like PF08746.11 KUM57498.1 - 3.9 7.9 19.8 0.031 14.6 4.6 2.5 2 0 0 2 2 2 0 RING-like domain zf-PHD-like PF15446.6 KUM57498.1 - 4.4 6.9 12.0 0.033 13.8 2.6 2.1 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 KUM57498.1 - 9.7 6.2 15.8 0.82 9.6 7.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RRM_1 PF00076.22 KUM57500.1 - 3e-20 71.8 0.0 4.2e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KUM57500.1 - 0.00037 20.1 0.0 0.00048 19.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M22 PF00814.25 KUM57501.1 - 5.9e-44 150.8 0.0 4.6e-43 147.9 0.0 2.1 1 1 0 1 1 1 1 Glycoprotease family FGGY_C PF02782.16 KUM57501.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Integrase_H2C2 PF17921.1 KUM57502.1 - 0.0098 16.0 0.1 0.015 15.4 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain Esterase PF00756.20 KUM57503.1 - 2.7e-51 174.6 0.0 6e-51 173.5 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KUM57503.1 - 1.6e-06 27.8 0.0 0.00019 21.0 0.0 2.1 2 0 0 2 2 2 2 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KUM57503.1 - 0.00024 20.7 0.0 0.00042 19.9 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KUM57503.1 - 0.00047 19.5 0.0 0.0013 18.1 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KUM57503.1 - 0.0083 15.1 0.0 0.03 13.2 0.0 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.25 KUM57503.1 - 0.042 13.7 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 KUM57503.1 - 0.11 11.1 0.0 0.23 10.1 0.0 1.6 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KUM57503.1 - 0.13 12.9 0.2 0.23 12.0 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KUM57503.1 - 0.14 11.1 0.0 0.6 9.1 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase Peptidase_C50 PF03568.17 KUM57504.1 - 2.8e-157 523.9 0.0 8.5e-156 519.0 0.0 3.0 3 0 0 3 3 3 1 Peptidase family C50 CHAT PF12770.7 KUM57504.1 - 1.9e-05 24.2 0.6 0.0027 17.2 0.0 3.2 2 1 0 2 2 2 1 CHAT domain TPR_2 PF07719.17 KUM57504.1 - 0.00018 21.3 10.6 1.2 9.5 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KUM57504.1 - 0.0012 19.1 20.0 1.9 8.9 0.0 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat RPN7 PF10602.9 KUM57504.1 - 0.0073 16.0 3.3 7.4 6.2 0.1 4.0 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_1 PF00515.28 KUM57504.1 - 0.033 14.0 2.6 18 5.4 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Csm2_III-A PF03750.13 KUM57504.1 - 0.035 14.9 0.9 0.26 12.1 0.1 2.7 2 0 0 2 2 2 0 Csm2 Type III-A TPR_10 PF13374.6 KUM57504.1 - 0.057 13.3 0.2 21 5.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KUM57504.1 - 0.33 11.3 5.2 16 6.0 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KUM57504.1 - 2.4 9.2 17.8 2.6 9.1 0.0 6.1 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KUM57504.1 - 3.1 8.5 12.0 47 4.7 0.0 6.3 6 0 0 6 6 5 0 Tetratricopeptide repeat AAA_23 PF13476.6 KUM57504.1 - 3.4 8.1 5.1 9.8 6.6 0.6 2.8 2 0 0 2 2 2 0 AAA domain Mito_carr PF00153.27 KUM57505.1 - 7.9e-73 240.5 0.1 1.6e-25 88.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.6 KUM57505.1 - 3.2e-13 48.4 5.6 1.8e-06 27.4 0.2 5.4 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 KUM57505.1 - 2.4e-12 47.1 4.3 3e-07 30.8 1.0 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KUM57505.1 - 3.3e-11 41.9 8.4 5.7e-06 25.5 0.2 5.2 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 KUM57505.1 - 1.3e-08 34.5 0.3 1.5 8.7 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KUM57505.1 - 1.2e-05 24.6 4.7 8.9e-05 21.8 0.3 3.3 3 0 0 3 3 3 1 EF hand GNAT_like PF18407.1 KUM57505.1 - 0.097 13.0 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyltransferase like domain DUF5321 PF17254.2 KUM57506.1 - 8.3e-43 145.6 5.0 1e-42 145.3 5.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) CCDC32 PF14989.6 KUM57506.1 - 0.0067 16.4 1.8 0.011 15.7 1.8 1.5 1 1 0 1 1 1 1 Coiled-coil domain containing 32 Homeodomain PF00046.29 KUM57508.1 - 6.6e-17 61.1 3.3 1.5e-16 60.0 2.4 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KUM57508.1 - 3.5e-06 26.8 0.5 9.6e-06 25.4 0.5 1.8 1 0 0 1 1 1 1 Homeobox KN domain DUF4638 PF15472.6 KUM57508.1 - 0.094 12.4 7.4 0.16 11.7 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) RR_TM4-6 PF06459.12 KUM57508.1 - 7 6.4 15.7 16 5.2 15.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HAD_2 PF13419.6 KUM57509.1 - 2.4e-19 70.1 0.0 3.2e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KUM57509.1 - 5.7e-08 33.3 0.0 1.2e-05 25.8 0.0 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KUM57509.1 - 2.9e-06 27.8 0.0 4.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KUM57509.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like CRC_subunit PF08624.10 KUM57512.1 - 2.3e-44 151.1 0.1 3.4e-44 150.6 0.1 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit His_Phos_1 PF00300.22 KUM57515.1 - 2.4e-08 33.9 0.1 1e-07 31.8 0.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GN3L_Grn1 PF08701.11 KUM57517.1 - 4e-21 74.9 18.6 4e-21 74.9 18.6 2.0 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KUM57517.1 - 5.4e-18 65.1 0.1 1.4e-13 50.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KUM57517.1 - 1.8e-07 31.3 0.1 2.9e-06 27.3 0.1 2.3 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KUM57517.1 - 1.5e-05 24.6 0.0 0.00017 21.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KUM57517.1 - 2.9e-05 23.7 0.3 0.27 10.8 0.3 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KUM57517.1 - 5e-05 23.4 7.0 0.44 10.6 0.1 4.3 3 2 2 5 5 5 2 Dynamin family MeaB PF03308.16 KUM57517.1 - 0.0053 15.8 0.0 0.0053 15.8 0.0 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 KUM57517.1 - 0.009 15.4 0.0 0.26 10.6 0.0 2.6 2 0 0 2 2 2 1 AIG1 family cobW PF02492.19 KUM57517.1 - 0.013 15.1 0.1 1.4 8.5 0.0 2.9 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain RNA_pol_3_Rpc31 PF11705.8 KUM57517.1 - 0.041 14.1 18.5 0.12 12.6 18.5 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOG1 PF06858.14 KUM57517.1 - 0.048 13.4 0.2 7.8 6.4 0.1 3.3 2 1 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) Roc PF08477.13 KUM57517.1 - 0.074 13.3 0.0 18 5.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM57517.1 - 0.087 12.3 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 KUM57517.1 - 0.19 12.3 2.6 0.2 12.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KUM57517.1 - 1.1 9.6 0.0 1.1 9.6 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain RRN3 PF05327.11 KUM57517.1 - 1.6 7.2 5.4 2 6.9 5.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CBFD_NFYB_HMF PF00808.23 KUM57518.1 - 2.5e-05 24.5 0.0 5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KUM57518.1 - 0.059 13.7 0.2 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Sporozoite_P67 PF05642.11 KUM57518.1 - 0.37 8.8 7.4 0.7 7.9 7.4 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen TFIIA PF03153.13 KUM57518.1 - 0.46 10.4 12.7 0.6 10.0 12.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 KUM57518.1 - 1.2 8.4 17.4 1.7 7.9 17.4 1.2 1 0 0 1 1 1 0 BUD22 CENP-X PF09415.10 KUM57518.1 - 1.5 9.2 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 CENP-S associating Centromere protein X SAPS PF04499.15 KUM57518.1 - 9.8 4.8 6.5 11 4.6 6.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SIR2 PF02146.17 KUM57519.1 - 6.3e-30 104.4 0.0 1.4e-29 103.3 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Chorismate_synt PF01264.21 KUM57520.1 - 1.2e-69 234.5 0.0 1.5e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Kelch_6 PF13964.6 KUM57521.1 - 3e-06 27.3 1.0 2.5 8.5 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 KUM57521.1 - 3.2e-05 23.8 0.1 0.0079 16.2 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 KUM57521.1 - 0.00041 20.3 0.0 0.037 14.0 0.0 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 KUM57521.1 - 0.0053 16.7 1.4 0.45 10.6 0.0 3.9 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.25 KUM57521.1 - 0.033 13.8 0.0 25 4.5 0.0 3.5 3 0 0 3 3 3 0 Kelch motif MFS_1 PF07690.16 KUM57522.1 - 9.1e-31 107.0 58.2 9.1e-31 107.0 58.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM57522.1 - 1e-10 40.7 16.6 1.4e-10 40.3 16.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Hemerythrin PF01814.23 KUM57523.1 - 9.2e-11 42.5 0.2 1.3e-10 42.0 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PET122 PF05476.11 KUM57523.1 - 0.1 11.9 0.2 0.12 11.6 0.2 1.2 1 0 0 1 1 1 0 PET122 KGG PF10685.9 KUM57524.1 - 3.5e-22 77.9 18.6 4.2e-09 36.4 0.8 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif BBE PF08031.12 KUM57525.1 - 1.2e-06 28.5 0.1 1.7e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Berberine and berberine like Pkinase PF00069.25 KUM57527.1 - 1.3e-52 178.8 0.1 2.5e-34 118.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KUM57527.1 - 7.7e-27 94.2 0.0 1.9e-25 89.6 0.0 3.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KUM57527.1 - 0.00041 19.2 0.2 0.0014 17.5 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KUM57527.1 - 0.0042 16.5 0.0 0.014 14.7 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KUM57527.1 - 0.0066 16.4 1.0 0.083 12.8 1.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RicinB_lectin_2 PF14200.6 KUM57528.1 - 2.4e-10 41.0 0.0 1.4e-06 28.9 0.0 2.8 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like SIR2 PF02146.17 KUM57529.1 - 3.7e-60 202.9 0.0 5e-60 202.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KUM57529.1 - 0.00091 19.0 0.0 0.18 11.5 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 KUM57529.1 - 0.0024 17.6 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPR_2 PF07719.17 KUM57530.1 - 8.4e-09 34.9 0.4 0.01 15.9 0.0 5.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KUM57530.1 - 4.9e-08 32.6 0.0 0.0018 18.3 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KUM57530.1 - 1.1e-07 32.0 7.3 2e-06 28.0 0.2 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KUM57530.1 - 6.1e-07 29.1 7.2 7.8e-06 25.5 0.2 2.5 2 1 0 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 KUM57530.1 - 9.2e-07 29.3 10.4 0.0091 16.5 1.4 4.0 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 KUM57530.1 - 1e-05 26.1 5.5 0.19 12.4 0.2 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KUM57530.1 - 1.9e-05 24.2 0.1 0.04 13.6 0.0 3.3 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.6 KUM57530.1 - 0.00011 22.7 13.3 0.14 13.1 0.6 5.8 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KUM57530.1 - 0.00022 20.9 0.1 0.063 13.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KUM57530.1 - 0.011 15.7 2.5 2.9 8.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM57530.1 - 0.012 15.9 0.4 6.7 7.0 0.0 3.1 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KUM57530.1 - 0.012 16.0 0.0 1.6e+02 3.1 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat ChAPs PF09295.10 KUM57530.1 - 0.025 13.6 0.6 1.2 8.0 0.1 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Vps39_1 PF10366.9 KUM57530.1 - 0.055 13.8 0.5 0.48 10.7 0.1 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_4 PF07721.14 KUM57530.1 - 0.055 14.1 7.1 0.08 13.6 0.1 4.1 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KUM57530.1 - 0.13 12.2 3.3 3.4 7.7 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KUM57530.1 - 0.14 12.3 10.0 13 6.0 0.5 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KUM57530.1 - 0.26 12.0 7.7 1.5e+02 3.3 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RWD PF05773.22 KUM57532.1 - 2.4e-24 85.8 1.0 2.4e-24 85.8 1.0 1.5 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 KUM57532.1 - 0.0057 17.1 14.6 0.029 14.9 14.3 2.2 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 ORC3_N PF07034.11 KUM57532.1 - 0.17 10.9 3.0 0.22 10.6 3.0 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus IBP39 PF11422.8 KUM57534.1 - 0.0068 16.2 10.7 0.024 14.4 0.8 2.8 2 1 1 3 3 3 2 Initiator binding protein 39 kDa Lantibiotic_a PF14867.6 KUM57534.1 - 0.064 13.0 6.5 3.6 7.4 0.1 3.2 3 0 0 3 3 3 0 Lantibiotic alpha UPF0020 PF01170.18 KUM57535.1 - 3.4e-07 30.1 0.0 0.023 14.4 0.0 2.3 1 1 1 2 2 2 2 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 KUM57535.1 - 0.086 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 N-6 DNA Methylase N6_N4_Mtase PF01555.18 KUM57535.1 - 0.089 12.5 0.0 0.58 9.8 0.1 2.1 2 0 0 2 2 2 0 DNA methylase Fungal_trans PF04082.18 KUM57536.1 - 6.7e-20 71.2 0.1 1.3e-19 70.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM57536.1 - 1.5e-09 37.8 9.8 2.9e-09 36.9 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L2_C PF03947.18 KUM57537.1 - 3.6e-51 172.6 2.3 2.7e-50 169.8 0.5 2.9 2 2 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KUM57537.1 - 1.3e-23 82.7 0.2 2.5e-23 81.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PAS PF00989.25 KUM57537.1 - 0.12 12.4 0.2 0.29 11.2 0.2 1.6 2 0 0 2 2 2 0 PAS fold Cyclin_N PF00134.23 KUM57538.1 - 1.9e-45 153.7 0.1 7.7e-45 151.7 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KUM57538.1 - 1.8e-35 121.6 0.0 3.1e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribonuc_P_40 PF08584.11 KUM57539.1 - 6.4e-73 245.5 0.0 8.3e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.32 KUM57540.1 - 1.8e-23 82.4 10.4 9.6e-07 29.4 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM57540.1 - 7.4e-16 58.2 0.0 0.01 16.1 0.0 6.2 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KUM57540.1 - 7.4e-09 34.6 0.0 8.7e-06 24.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 KUM57540.1 - 8e-05 22.6 0.0 0.15 11.9 0.0 3.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 KUM57540.1 - 0.023 13.7 0.3 0.042 12.8 0.0 1.5 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 KUM57540.1 - 0.03 13.0 0.2 0.42 9.2 0.1 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 VID27 PF08553.10 KUM57540.1 - 0.13 11.3 0.1 0.69 8.9 0.0 1.9 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain PD40 PF07676.12 KUM57540.1 - 0.98 9.4 9.2 17 5.5 0.1 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Zn_clus PF00172.18 KUM57541.1 - 4.2e-08 33.2 5.6 9e-08 32.1 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF702 PF05142.12 KUM57541.1 - 2.5 8.6 8.2 0.83 10.1 5.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF702) PBP PF01161.20 KUM57542.1 - 4.1e-13 49.8 0.1 5.1e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GFA PF04828.14 KUM57543.1 - 4.1e-24 84.8 0.0 6.1e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 KUM57543.1 - 0.3 11.1 4.0 1.8 8.7 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon SMP PF04927.12 KUM57545.1 - 3.9e-15 56.1 14.6 1.6e-05 25.2 5.5 3.3 2 1 1 3 3 3 3 Seed maturation protein MFS_1 PF07690.16 KUM57546.1 - 3e-46 158.0 24.8 5.7e-46 157.0 24.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM57546.1 - 2.2e-08 33.4 8.9 2.2e-08 33.4 8.9 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KUM57546.1 - 3.5e-06 25.8 4.5 3.5e-06 25.8 4.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KUM57546.1 - 0.0006 18.3 6.2 0.0006 18.3 6.2 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector Citrate_synt PF00285.21 KUM57547.1 - 4.1e-82 276.1 0.0 5e-82 275.9 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Sugar_tr PF00083.24 KUM57548.1 - 4e-78 263.3 27.6 4.7e-78 263.1 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM57548.1 - 1.8e-19 69.9 36.6 9.9e-19 67.5 29.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.21 KUM57549.1 - 9.2e-12 44.9 0.1 2.3e-11 43.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KUM57549.1 - 8.8e-10 38.0 0.0 1.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KUM57549.1 - 1.7e-09 37.2 0.1 3.6e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KUM57549.1 - 7.6e-09 35.4 0.0 1.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KUM57549.1 - 6.7e-07 29.4 0.2 1.2e-06 28.5 0.1 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KUM57549.1 - 9.4e-06 25.3 0.1 1.5e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KUM57549.1 - 9.2e-05 22.7 0.1 0.49 10.6 0.0 2.7 2 1 1 3 3 3 2 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KUM57549.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GFA PF04828.14 KUM57550.1 - 1.2e-21 76.8 0.0 1.6e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 KUM57550.1 - 0.065 13.2 0.1 0.065 13.2 0.1 2.1 2 0 0 2 2 2 0 Nudix N-terminal PBP PF01161.20 KUM57551.1 - 1.1e-19 71.0 0.0 1.4e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L23 PF00276.20 KUM57551.1 - 0.088 13.2 0.1 0.14 12.5 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L23 DUF4958 PF16319.5 KUM57554.1 - 0.078 11.0 0.1 0.089 10.8 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4958) ATG22 PF11700.8 KUM57555.1 - 1.3e-156 522.0 10.0 1.5e-156 521.8 10.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KUM57555.1 - 6.8e-05 21.9 20.8 6.8e-05 21.9 20.8 3.1 2 1 0 3 3 3 2 Major Facilitator Superfamily TMEM252 PF15664.5 KUM57555.1 - 0.034 13.9 0.2 0.067 12.9 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 252 family BAR PF03114.18 KUM57556.1 - 6.5e-53 179.8 5.8 1.7e-52 178.5 1.5 2.1 2 0 0 2 2 2 2 BAR domain DUF3340 PF11818.8 KUM57556.1 - 0.0032 17.6 0.8 0.0064 16.7 0.8 1.5 1 0 0 1 1 1 1 C-terminal domain of tail specific protease (DUF3340) CP12 PF02672.15 KUM57556.1 - 0.016 15.9 0.0 0.084 13.6 0.0 2.3 2 0 0 2 2 2 0 CP12 domain SbcD_C PF12320.8 KUM57556.1 - 4.8 7.6 7.2 2.6 8.4 0.3 2.7 2 1 1 3 3 3 0 Type 5 capsule protein repressor C-terminal domain eIF-6 PF01912.18 KUM57558.1 - 7.3e-80 267.0 0.8 9.5e-80 266.6 0.8 1.1 1 0 0 1 1 1 1 eIF-6 family Pept_tRNA_hydro PF01195.19 KUM57561.1 - 8.8e-18 64.8 0.0 4.6e-10 39.7 0.0 2.9 1 1 1 2 2 2 2 Peptidyl-tRNA hydrolase Pkinase PF00069.25 KUM57562.1 - 9.9e-48 162.8 0.0 1.8e-47 162.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM57562.1 - 9.6e-27 93.9 0.0 1.5e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KUM57562.1 - 0.005 16.2 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KUM57562.1 - 0.005 16.2 0.0 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KUM57562.1 - 0.019 14.9 0.9 1.2 9.0 0.0 3.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Sybindin PF04099.12 KUM57563.1 - 1.1e-16 61.0 0.1 1.3e-16 60.9 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KUM57563.1 - 0.014 15.5 0.2 0.017 15.2 0.2 1.1 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region AT_hook PF02178.19 KUM57565.1 - 0.0033 17.1 1.3 0.021 14.6 1.3 2.6 1 0 0 1 1 1 1 AT hook motif Pkinase PF00069.25 KUM57566.1 - 1.3e-51 175.5 0.1 9.8e-46 156.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KUM57566.1 - 7.2e-35 120.5 0.0 5.5e-33 114.3 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KUM57566.1 - 1e-07 31.6 0.0 1.1e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KUM57566.1 - 0.00084 19.3 0.1 0.0014 18.6 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KUM57566.1 - 0.0014 17.5 0.0 0.0047 15.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase SRI PF08236.11 KUM57568.1 - 1.4e-18 66.8 9.5 3.8e-18 65.4 9.5 1.8 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KUM57568.1 - 9.5e-17 61.9 2.1 2.3e-16 60.6 0.2 2.7 2 1 0 2 2 2 1 SET domain AWS PF17907.1 KUM57568.1 - 7e-11 42.0 9.2 7e-11 42.0 9.2 2.1 2 0 0 2 2 2 1 AWS domain WW PF00397.26 KUM57568.1 - 0.00023 21.2 1.8 0.00062 19.8 1.8 1.8 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 KUM57568.1 - 0.00023 21.1 0.9 0.00052 20.0 0.1 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DUF4706 PF15797.5 KUM57568.1 - 0.1 13.1 1.5 0.32 11.5 1.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4706) CENP-X PF09415.10 KUM57568.1 - 0.17 12.2 0.1 0.48 10.8 0.1 1.8 1 0 0 1 1 1 0 CENP-S associating Centromere protein X PHD PF00628.29 KUM57569.1 - 1.4e-08 34.5 9.2 1.4e-08 34.5 9.2 1.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KUM57569.1 - 0.0047 16.4 5.9 0.0047 16.4 5.9 1.9 2 0 0 2 2 2 1 PHD-finger DUF1524 PF07510.11 KUM57569.1 - 0.0054 16.6 1.5 0.017 15.0 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1524) C1_2 PF03107.16 KUM57569.1 - 4.5 7.7 5.9 1.4 9.3 1.9 2.1 2 0 0 2 2 2 0 C1 domain Prefoldin_2 PF01920.20 KUM57570.1 - 2.5e-18 66.0 5.8 3e-18 65.7 5.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit T6PP_N PF18572.1 KUM57570.1 - 0.24 11.3 5.3 0.78 9.6 5.3 1.8 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain CENP-H PF05837.12 KUM57570.1 - 1 9.8 7.1 3 8.3 0.7 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4200 PF13863.6 KUM57570.1 - 2.6 8.5 10.2 2.6 8.5 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) HMG_box PF00505.19 KUM57571.1 - 1.8e-11 44.2 0.2 4.1e-11 43.1 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KUM57571.1 - 0.011 16.3 0.5 0.011 16.3 0.5 2.0 2 0 0 2 2 2 0 HMG-box domain MATalpha_HMGbox PF04769.12 KUM57571.1 - 0.17 11.2 0.1 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Rcd1 PF04078.13 KUM57572.1 - 4.2e-126 419.5 2.4 5e-126 419.3 2.4 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TFIIA PF03153.13 KUM57572.1 - 2.6 8.0 14.6 3.2 7.7 14.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ARS2 PF04959.13 KUM57572.1 - 8.3 6.7 10.2 13 6.1 10.2 1.2 1 0 0 1 1 1 0 Arsenite-resistance protein 2 DUF202 PF02656.15 KUM57573.1 - 0.086 13.3 0.1 1.9 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Insulin_TMD PF17870.1 KUM57573.1 - 0.47 10.6 1.6 1.2 9.3 1.6 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment IPTL-CTERM PF18203.1 KUM57573.1 - 1.2 9.1 4.3 4.9 7.1 0.4 2.6 2 0 0 2 2 2 0 IPTL-CTERM motif DUF4690 PF15756.5 KUM57573.1 - 2 9.1 8.8 0.1 13.2 1.9 2.4 3 0 0 3 3 3 0 Small Novel Rich in Cartilage Gram_pos_anchor PF00746.21 KUM57573.1 - 3.8 7.5 11.1 1.8 8.6 0.1 3.3 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Abhydrolase_1 PF00561.20 KUM57574.1 - 1.8e-18 67.1 0.2 1.2e-17 64.5 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KUM57574.1 - 5.9e-18 66.3 0.1 1e-17 65.5 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM57574.1 - 8.4e-05 22.0 0.0 0.0023 17.2 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KUM57574.1 - 0.08 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase XPC-binding PF09280.11 KUM57574.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 XPC-binding domain CorA PF01544.18 KUM57576.1 - 4.3e-14 52.5 0.0 5.2e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AA_permease PF00324.21 KUM57577.1 - 6.3e-121 404.3 40.9 7.6e-121 404.0 40.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM57577.1 - 9.3e-30 103.8 44.1 1.2e-29 103.4 44.1 1.1 1 0 0 1 1 1 1 Amino acid permease PMBR PF09373.10 KUM57577.1 - 0.044 14.0 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 Pseudomurein-binding repeat Ribonuclease PF00545.20 KUM57578.1 - 3.2e-09 37.4 0.2 4.2e-09 37.0 0.2 1.2 1 0 0 1 1 1 1 ribonuclease MF_alpha_N PF05436.11 KUM57578.1 - 0.035 14.0 0.2 0.049 13.5 0.2 1.4 1 1 0 1 1 1 0 Mating factor alpha precursor N-terminus GST_N_3 PF13417.6 KUM57579.1 - 8.3e-16 58.2 0.0 1.8e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KUM57579.1 - 1.3e-10 41.5 0.1 3.4e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KUM57579.1 - 1.9e-10 40.9 0.0 4e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KUM57579.1 - 4.1e-10 39.7 0.1 6.6e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KUM57579.1 - 5.7e-09 36.1 0.1 1.2e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KUM57579.1 - 1.3e-06 28.4 0.0 2.5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KUM57579.1 - 0.0018 19.0 0.0 0.0073 17.0 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_5 PF16865.5 KUM57579.1 - 0.0027 18.3 0.0 0.046 14.3 0.0 2.2 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.18 KUM57580.1 - 0.0012 18.9 13.0 0.0012 18.9 13.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGAP PF00620.27 KUM57580.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 RhoGAP domain Methyltransf_31 PF13847.6 KUM57581.1 - 3.3e-30 104.9 0.0 4.4e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM57581.1 - 2.8e-25 88.8 0.0 5.2e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM57581.1 - 1e-24 87.0 0.0 1.7e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM57581.1 - 9.2e-20 71.0 0.0 1.3e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KUM57581.1 - 1.3e-17 64.1 0.0 1.8e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM57581.1 - 2.1e-16 60.5 0.0 3.7e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KUM57581.1 - 3.2e-08 33.3 0.0 4.6e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KUM57581.1 - 3.7e-08 33.2 0.0 5.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KUM57581.1 - 1.1e-06 28.6 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KUM57581.1 - 1.8e-06 27.5 0.0 2.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.11 KUM57581.1 - 0.00021 20.9 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 KUM57581.1 - 0.00057 18.9 0.0 0.0009 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.19 KUM57581.1 - 0.0028 17.8 0.0 0.0038 17.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KUM57581.1 - 0.0032 16.8 0.0 0.0038 16.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_18 PF12847.7 KUM57581.1 - 0.0041 17.1 0.0 0.0078 16.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KUM57581.1 - 0.0044 16.7 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit DREV PF05219.12 KUM57581.1 - 0.0057 15.8 0.0 0.012 14.7 0.0 1.6 1 1 0 1 1 1 1 DREV methyltransferase CMAS PF02353.20 KUM57581.1 - 0.0062 15.9 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KUM57581.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 KUM57581.1 - 0.015 14.4 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 KUM57581.1 - 0.016 15.2 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KUM57581.1 - 0.024 14.0 0.0 0.032 13.6 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 KUM57581.1 - 0.046 13.6 0.0 0.54 10.1 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_29 PF03141.16 KUM57581.1 - 0.19 10.2 0.0 0.87 8.1 0.0 1.7 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase WW PF00397.26 KUM57582.1 - 1.3e-06 28.3 0.4 1.3e-06 28.3 0.4 2.3 2 0 0 2 2 2 1 WW domain ThrE PF06738.12 KUM57583.1 - 1.3e-68 231.0 22.5 2.9e-62 210.2 5.0 3.0 2 1 1 3 3 3 3 Putative threonine/serine exporter ThrE_2 PF12821.7 KUM57583.1 - 5.4e-13 49.2 9.1 5.4e-13 49.2 9.1 3.1 2 1 1 3 3 3 1 Threonine/Serine exporter, ThrE Na_Ca_ex PF01699.24 KUM57584.1 - 2.2e-39 134.9 40.1 1.2e-19 70.7 19.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YrzO PF14142.6 KUM57584.1 - 0.12 12.3 0.3 0.26 11.2 0.3 1.5 1 0 0 1 1 1 0 YrzO-like protein Anoctamin PF04547.12 KUM57585.1 - 1e-93 314.7 1.9 1.3e-93 314.3 1.9 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Ferric_reduct PF01794.19 KUM57586.1 - 0.078 13.1 1.5 5 7.2 0.2 2.5 2 0 0 2 2 2 0 Ferric reductase like transmembrane component YbgT_YccB PF08173.11 KUM57586.1 - 2 8.6 5.3 0.38 10.9 0.8 2.1 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Spc7_N PF15402.6 KUM57587.1 - 0 1068.0 75.6 8.4e-200 666.4 44.3 3.1 1 1 2 3 3 3 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 KUM57587.1 - 2e-128 427.6 5.5 4.2e-128 426.6 5.5 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3016 PF11454.8 KUM57587.1 - 0.014 15.2 0.1 0.039 13.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) FapA PF03961.13 KUM57587.1 - 2.9 6.4 7.2 0.99 7.9 4.3 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A Atg14 PF10186.9 KUM57587.1 - 6.5 5.7 14.8 0.16 11.0 6.5 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1932 PF09130.11 KUM57588.1 - 1.3e-14 53.9 0.0 2.7e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.17 KUM57588.1 - 1.5e-05 25.5 0.0 3.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KUM57588.1 - 2e-05 24.8 0.1 6.8e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KUM57588.1 - 0.0028 17.1 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_transf_21 PF13506.6 KUM57588.1 - 0.081 12.4 0.1 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 21 Rossmann-like PF10727.9 KUM57588.1 - 0.2 11.5 3.0 0.99 9.3 0.3 2.8 3 0 0 3 3 3 0 Rossmann-like domain Fungal_trans PF04082.18 KUM57589.1 - 2.9e-17 62.6 0.1 6.6e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM57589.1 - 5.5e-07 29.6 13.1 9.8e-07 28.8 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM57592.1 - 1.3e-23 83.4 0.5 2.4e-23 82.5 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KUM57593.1 - 1.2e-38 133.0 28.4 1.2e-38 133.0 28.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily bZIP_2 PF07716.15 KUM57594.1 - 7e-14 51.7 13.3 1.1e-13 51.0 13.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KUM57594.1 - 0.00038 20.5 11.4 0.00074 19.6 11.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor SIKE PF05769.11 KUM57594.1 - 0.028 14.4 1.6 0.039 13.9 1.6 1.1 1 0 0 1 1 1 0 SIKE family DUF4094 PF13334.6 KUM57594.1 - 0.049 14.1 0.2 0.081 13.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) ANTH PF07651.16 KUM57595.1 - 9.4e-59 198.7 0.0 1.2e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KUM57595.1 - 4.7e-07 29.9 0.0 2.4e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 ENTH domain Ribosomal_S17_N PF16205.5 KUM57597.1 - 1.1e-33 115.4 0.6 2.3e-33 114.4 0.6 1.6 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KUM57597.1 - 4.6e-27 93.9 1.0 4.6e-27 93.9 1.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S17 Mac_assoc PF16628.5 KUM57598.1 - 7.5e-77 257.7 9.6 7.5e-77 257.7 9.6 2.3 2 1 0 2 2 2 1 Unstructured region on maltose acetyltransferase Mac PF12464.8 KUM57598.1 - 9.2e-12 45.0 0.0 2.9e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.18 KUM57598.1 - 2e-09 37.4 8.2 3.6e-09 36.6 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep PF00132.24 KUM57598.1 - 7.5e-09 35.0 6.1 0.0001 21.9 0.3 3.7 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KUM57598.1 - 4.7e-05 23.0 1.4 4.7e-05 23.0 1.4 3.4 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase CRM1_C PF08767.11 KUM57599.1 - 2.7e-102 342.2 2.0 2.7e-102 342.2 2.0 3.0 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KUM57599.1 - 6.5e-43 146.3 4.5 6.5e-43 146.3 4.5 4.0 5 0 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KUM57599.1 - 2.4e-33 113.6 4.7 9.2e-33 111.7 4.7 2.1 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KUM57599.1 - 8e-29 99.5 0.6 8e-29 99.5 0.6 2.8 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KUM57599.1 - 3.8e-19 67.9 0.8 8.8e-19 66.7 0.8 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KUM57599.1 - 1.2e-11 44.4 0.1 4.6e-11 42.5 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KUM57599.1 - 0.00084 19.3 1.0 0.088 12.7 0.0 4.3 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) Hemocyanin_M PF00372.19 KUM57599.1 - 0.085 12.0 0.1 0.18 10.9 0.1 1.5 1 0 0 1 1 1 0 Hemocyanin, copper containing domain DRE2_N PF16803.5 KUM57599.1 - 0.095 13.0 0.4 0.7 10.1 0.0 2.6 3 0 0 3 3 3 0 Fe-S cluster assembly protein DRE2 N-terminus ALAD PF00490.21 KUM57600.1 - 3.5e-121 404.3 0.0 4.1e-121 404.0 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Shugoshin_N PF07558.11 KUM57602.1 - 7.7e-19 67.3 5.0 2.1e-18 65.9 5.0 1.8 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KUM57602.1 - 1.8e-11 43.6 5.5 6.5e-11 41.8 5.5 2.0 1 0 0 1 1 1 1 Shugoshin C terminus bZIP_2 PF07716.15 KUM57602.1 - 0.017 15.2 0.3 0.079 13.1 0.3 2.2 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 KUM57602.1 - 0.031 14.4 1.4 0.16 12.0 1.4 2.4 1 0 0 1 1 1 0 bZIP transcription factor DASH_Dad2 PF08654.10 KUM57603.1 - 6.1e-29 100.4 0.0 8.1e-29 100.0 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.22 KUM57603.1 - 0.022 15.0 0.1 0.033 14.4 0.1 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DAO PF01266.24 KUM57605.1 - 1.8e-51 175.8 0.0 2.5e-51 175.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KUM57605.1 - 2.2e-43 147.1 0.0 4.1e-43 146.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KUM57605.1 - 1.2e-08 34.5 0.4 2.8e-08 33.3 0.4 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KUM57605.1 - 0.00022 20.7 0.7 0.00094 18.6 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM57605.1 - 0.00038 19.8 0.1 0.0014 17.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM57605.1 - 0.0011 19.1 0.1 0.0062 16.7 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KUM57605.1 - 0.012 14.8 0.0 0.035 13.3 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KUM57605.1 - 0.025 13.3 0.2 0.042 12.5 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 KUM57605.1 - 0.027 14.4 0.1 0.051 13.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KUM57605.1 - 0.027 13.7 0.1 0.054 12.7 0.1 1.6 1 1 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KUM57605.1 - 0.034 14.7 0.2 0.12 12.9 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KUM57605.1 - 0.057 12.7 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KUM57605.1 - 0.13 11.3 0.3 0.61 9.1 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Ecl1 PF12855.7 KUM57606.1 - 7.2e-10 40.3 11.2 1.5e-09 39.3 11.2 1.4 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins Cadherin_C PF01049.17 KUM57606.1 - 0.013 15.8 0.9 0.016 15.5 0.9 1.1 1 0 0 1 1 1 0 Cadherin cytoplasmic region DUF1804 PF08822.11 KUM57606.1 - 0.045 13.7 0.2 0.049 13.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) p450 PF00067.22 KUM57607.1 - 1.8e-72 244.6 0.0 2e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CRM1_C PF08767.11 KUM57608.1 - 7.4e-24 84.5 0.4 8.6e-24 84.3 0.4 1.0 1 0 0 1 1 1 1 CRM1 C terminal Aa_trans PF01490.18 KUM57610.1 - 2.8e-32 112.0 16.2 3.3e-32 111.7 16.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Gate PF07670.14 KUM57610.1 - 0.087 13.1 3.3 0.16 12.2 0.6 2.3 1 1 1 2 2 2 0 Nucleoside recognition Trp_Tyr_perm PF03222.13 KUM57610.1 - 0.86 8.6 18.5 0.043 12.8 12.7 1.6 2 0 0 2 2 2 0 Tryptophan/tyrosine permease family DUF3632 PF12311.8 KUM57611.1 - 9.7e-27 94.5 0.0 1.3e-26 94.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Bradykinin PF06753.12 KUM57611.1 - 0.17 11.7 0.6 0.37 10.6 0.6 1.5 1 0 0 1 1 1 0 Bradykinin GA-like PF17573.2 KUM57611.1 - 0.24 11.4 3.0 0.23 11.4 0.8 2.0 2 0 0 2 2 2 0 GA-like domain PLAC8 PF04749.17 KUM57612.1 - 7.2e-20 71.8 13.0 1.2e-19 71.1 13.0 1.4 1 0 0 1 1 1 1 PLAC8 family SID-1_RNA_chan PF13965.6 KUM57612.1 - 4.3 5.6 6.5 22 3.3 0.0 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF853 PF05872.12 KUM57612.1 - 6.8 5.2 7.2 9.5 4.7 7.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) ERCC4 PF02732.15 KUM57614.1 - 2.6e-33 115.4 0.0 4.6e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain DUF4432 PF14486.6 KUM57614.1 - 0.063 12.1 0.2 0.13 11.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) Glycos_transf_1 PF00534.20 KUM57615.1 - 4.6e-32 110.9 0.1 1.2e-20 73.7 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KUM57615.1 - 2.4e-16 60.2 0.1 9.6e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KUM57615.1 - 5.2e-13 49.6 0.1 2.3e-12 47.5 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KUM57615.1 - 7.6e-07 29.7 3.4 3.4e-06 27.6 3.4 2.1 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KUM57615.1 - 0.017 15.5 0.0 0.048 14.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 MFS_1 PF07690.16 KUM57616.1 - 3.7e-22 78.7 15.2 3.7e-22 78.7 15.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KUM57616.1 - 8.8e-07 28.7 2.7 3.9e-06 26.6 2.0 2.0 2 0 0 2 2 2 1 Nodulin-like Imm35 PF15567.6 KUM57616.1 - 0.11 12.7 1.3 0.25 11.5 1.3 1.6 1 0 0 1 1 1 0 Immunity protein 35 Kinesin PF00225.23 KUM57617.1 - 3.6e-92 308.8 0.1 3.6e-92 308.8 0.1 3.0 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KUM57617.1 - 4.1e-21 75.5 0.0 1.1e-16 61.1 0.0 3.2 1 1 1 2 2 2 2 Microtubule binding DUF641 PF04859.12 KUM57617.1 - 0.0097 16.2 2.5 0.0097 16.2 2.5 10.6 5 3 4 9 9 9 1 Plant protein of unknown function (DUF641) DUF4726 PF15855.5 KUM57617.1 - 1.1 9.5 4.4 2.8 8.2 0.3 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4726) SAP PF02037.27 KUM57617.1 - 5.2 6.9 8.0 7.2 6.5 0.0 4.5 4 0 0 4 4 4 0 SAP domain IPK PF03770.16 KUM57618.1 - 2.4e-58 197.3 0.0 3.9e-58 196.6 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.10 KUM57618.1 - 0.041 13.7 0.1 0.08 12.8 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 MFS_1 PF07690.16 KUM57619.1 - 7.6e-16 58.0 45.9 7.6e-16 58.0 45.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM57619.1 - 3.4e-10 39.0 10.2 3.4e-10 39.0 10.2 2.0 1 1 2 3 3 3 1 Fungal trichothecene efflux pump (TRI12) ATG2_CAD PF13329.6 KUM57620.1 - 1.2e-46 158.3 0.0 3.3e-46 156.8 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KUM57620.1 - 1.1e-29 102.6 0.0 3.6e-29 100.9 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain A_deaminase PF00962.22 KUM57621.1 - 2.2e-21 76.5 0.0 3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF2767 PF10965.8 KUM57621.1 - 0.045 13.7 0.1 0.092 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) LtuB PF17455.2 KUM57621.1 - 0.098 13.3 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 Late transcription unit B Nucleos_tra2_C PF07662.13 KUM57623.1 - 1.5e-73 247.1 0.4 1.5e-73 247.1 0.4 2.8 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KUM57623.1 - 3.1e-22 79.0 6.7 3.1e-22 79.0 6.7 2.8 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus MAS20 PF02064.15 KUM57624.1 - 0.042 13.9 0.8 0.091 12.9 0.8 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor Amino_oxidase PF01593.24 KUM57626.1 - 6.5e-65 220.2 0.6 7.2e-64 216.7 0.6 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KUM57626.1 - 2.1e-10 40.7 0.1 5.7e-10 39.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM57626.1 - 1.1e-06 28.1 0.1 0.0074 15.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM57626.1 - 5.5e-05 22.6 0.4 0.18 11.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KUM57626.1 - 8.6e-05 21.9 0.5 0.014 14.7 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 KUM57626.1 - 0.00034 21.1 1.5 0.12 13.0 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM57626.1 - 0.0018 17.9 0.3 0.33 10.5 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 KUM57626.1 - 0.0022 17.2 0.1 0.0079 15.3 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KUM57626.1 - 0.0041 16.4 0.2 0.011 15.0 0.2 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KUM57626.1 - 0.0053 16.2 1.4 0.033 13.5 0.6 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KUM57626.1 - 0.016 13.9 1.6 0.63 8.7 0.1 2.7 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.24 KUM57626.1 - 0.017 14.2 1.1 0.019 14.1 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KUM57626.1 - 0.035 13.4 0.1 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 Thi4 family ThiF PF00899.21 KUM57626.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 KUM57626.1 - 0.18 11.8 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Conotoxin PF02950.17 KUM57628.1 - 0.14 13.1 10.7 3.4 8.7 10.7 2.1 1 1 0 1 1 1 0 Conotoxin Toxin_21 PF08091.11 KUM57628.1 - 0.17 11.8 9.9 0.32 10.9 9.9 1.4 1 0 0 1 1 1 0 Spider insecticidal peptide Glyco_hydro_43 PF04616.14 KUM57629.1 - 1.2e-32 113.4 8.4 1.5e-32 113.1 8.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 SprB PF13573.6 KUM57629.1 - 0.25 11.1 2.3 2.4 8.0 0.2 2.5 2 0 0 2 2 2 0 SprB repeat DUF3337 PF11816.8 KUM57630.1 - 0.0016 18.4 0.0 0.0057 16.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) Pkinase PF00069.25 KUM57631.1 - 7.6e-71 238.6 0.0 1.2e-70 237.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM57631.1 - 4.1e-44 150.8 0.0 6.8e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KUM57631.1 - 7.8e-22 77.4 0.7 1.7e-21 76.4 0.1 2.0 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 KUM57631.1 - 1.6e-06 27.7 0.0 3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KUM57631.1 - 2e-06 26.9 0.0 2e-06 26.9 0.0 2.2 3 1 0 3 3 3 1 Fungal protein kinase Haspin_kinase PF12330.8 KUM57631.1 - 0.045 12.7 0.3 0.25 10.2 0.3 2.1 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KUM57631.1 - 0.053 13.4 2.5 0.61 10.0 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KUM57631.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VHS PF00790.19 KUM57632.1 - 6.8e-35 120.0 0.6 1.2e-34 119.2 0.6 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KUM57632.1 - 2.4e-16 59.0 0.0 5.7e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KUM57632.1 - 1.7e-14 53.4 0.1 3.2e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KUM57632.1 - 7.6e-14 51.1 0.0 1.5e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KUM57632.1 - 6.4e-10 39.2 1.7 1.5e-09 38.0 1.7 1.7 1 0 0 1 1 1 1 GAT domain Hrs_helical PF12210.8 KUM57632.1 - 0.065 13.8 0.2 0.18 12.3 0.2 1.7 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate UIM PF02809.20 KUM57632.1 - 0.11 12.5 3.3 0.27 11.2 3.3 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif F-box PF00646.33 KUM57633.1 - 0.051 13.5 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 F-box domain DUF5050 PF16472.5 KUM57634.1 - 0.021 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) GATase PF00117.28 KUM57635.1 - 0.011 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Fungal_trans PF04082.18 KUM57636.1 - 8.8e-13 47.9 2.5 1.4e-11 43.9 2.5 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain UCH_1 PF13423.6 KUM57637.1 - 2.3e-94 316.6 0.0 3e-94 316.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KUM57637.1 - 1.3e-15 58.3 0.0 6.3e-15 56.1 0.0 2.1 2 0 0 2 2 2 1 Exonuclease UCH PF00443.29 KUM57637.1 - 0.00013 21.5 0.0 0.00098 18.7 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase LOR PF04525.12 KUM57638.1 - 1.6e-07 31.1 0.0 3.1e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 LURP-one-related AA_permease_2 PF13520.6 KUM57639.1 - 2.8e-45 154.9 51.0 3.4e-45 154.7 51.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM57639.1 - 2e-16 59.7 42.0 2.8e-16 59.2 42.0 1.1 1 0 0 1 1 1 1 Amino acid permease Aldose_epim PF01263.20 KUM57640.1 - 1.1e-38 133.3 0.1 1.4e-38 132.9 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase LBP_BPI_CETP_C PF02886.17 KUM57640.1 - 0.14 11.5 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain MFS_1 PF07690.16 KUM57641.1 - 1.1e-28 100.2 20.4 2.1e-28 99.3 20.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TPR_4 PF07721.14 KUM57642.1 - 0.065 13.9 0.1 6.8 7.6 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Bac_thur_toxin PF01338.18 KUM57645.1 - 0.033 13.6 0.2 0.056 12.9 0.2 1.3 1 0 0 1 1 1 0 Bacillus thuringiensis toxin Glyco_hydro_3_C PF01915.22 KUM57646.1 - 1.4e-59 201.5 0.0 2.3e-59 200.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KUM57646.1 - 2.5e-50 171.7 0.0 4.1e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KUM57646.1 - 8e-23 80.3 2.0 2.1e-22 79.0 1.4 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KUM57646.1 - 1.8e-16 60.2 0.2 3.6e-16 59.3 0.2 1.5 1 0 0 1 1 1 1 PA14 domain SNF PF00209.18 KUM57648.1 - 1.5e-74 251.6 30.4 1.5e-74 251.6 30.4 2.3 2 1 0 2 2 2 1 Sodium:neurotransmitter symporter family DUF3810 PF12725.7 KUM57648.1 - 0.083 12.2 0.7 0.2 10.9 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) PSCyt3 PF07627.11 KUM57649.1 - 0.032 14.5 0.2 0.062 13.6 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1588) PMP22_Claudin PF00822.20 KUM57652.1 - 0.00019 21.4 5.4 0.00028 20.8 5.4 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family ABC2_membrane PF01061.24 KUM57652.1 - 0.00035 20.1 2.8 0.00035 20.1 2.8 1.9 1 1 1 2 2 2 1 ABC-2 type transporter MRAP PF15183.6 KUM57652.1 - 0.11 12.4 2.7 0.65 10.0 0.3 2.3 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family DUF5389 PF17364.2 KUM57652.1 - 0.42 10.7 4.9 0.85 9.7 0.6 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5389) DUF4173 PF13777.6 KUM57652.1 - 1.6 8.1 9.2 0.12 11.8 2.4 2.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4173) CitMHS PF03600.16 KUM57652.1 - 5.7 6.1 11.0 7.5 5.6 11.0 1.1 1 0 0 1 1 1 0 Citrate transporter DUF3817 PF12823.7 KUM57652.1 - 6.3 7.7 10.9 42 5.0 7.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3817) DUF1129 PF06570.11 KUM57652.1 - 8.1 5.9 10.6 13 5.2 9.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) FAD_binding_3 PF01494.19 KUM57653.1 - 7.7e-13 48.4 0.2 2.5e-12 46.7 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KUM57653.1 - 6.1e-05 22.8 0.4 0.00044 19.9 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM57653.1 - 0.00016 21.0 0.1 0.00043 19.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM57653.1 - 0.00022 21.4 0.0 0.00089 19.4 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KUM57653.1 - 0.0049 16.2 0.1 0.0077 15.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KUM57653.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM57653.1 - 0.021 14.8 0.2 0.23 11.4 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KUM57653.1 - 0.034 12.8 0.1 0.067 11.9 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KUM57653.1 - 0.038 14.6 0.1 0.29 11.7 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM57653.1 - 0.059 12.4 0.1 0.099 11.7 0.1 1.5 1 1 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KUM57653.1 - 0.11 11.5 0.2 0.84 8.6 0.2 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.16 KUM57654.1 - 4.9e-27 94.8 34.9 1.6e-20 73.4 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM57654.1 - 2.2e-16 59.8 21.7 1.5e-15 57.1 21.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter DIOX_N PF14226.6 KUM57655.1 - 1.2e-29 103.5 0.0 2.2e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KUM57655.1 - 9.2e-23 80.7 0.0 1.8e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APH PF01636.23 KUM57656.1 - 2.5e-08 34.2 0.0 0.0054 16.7 0.0 2.3 2 1 0 2 2 2 2 Phosphotransferase enzyme family Oxidored_FMN PF00724.20 KUM57657.1 - 1.4e-87 294.2 0.0 1.7e-87 293.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KUM57657.1 - 0.17 11.3 0.0 0.65 9.4 0.0 1.9 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Fungal_trans PF04082.18 KUM57658.1 - 1.4e-36 126.0 1.2 2e-36 125.4 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KUM57658.1 - 3.6e-05 24.0 19.7 0.0063 16.9 4.2 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM57658.1 - 0.0067 17.2 15.1 0.14 13.1 1.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KUM57658.1 - 0.4 11.0 2.5 1.2 9.5 2.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon FMN_dh PF01070.18 KUM57659.1 - 9.7e-94 314.2 0.0 5.7e-93 311.7 0.0 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KUM57659.1 - 6.2e-06 26.3 0.0 1.5e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KUM57659.1 - 1.7e-05 24.1 0.0 2.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KUM57659.1 - 0.00016 20.8 0.0 0.00031 19.9 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KUM57659.1 - 0.034 13.6 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.15 KUM57659.1 - 0.17 11.3 0.2 0.3 10.4 0.2 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase Polysacc_deac_1 PF01522.21 KUM57660.1 - 3.1e-20 72.3 0.0 5.7e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KUM57660.1 - 7.7e-05 22.4 0.0 0.00017 21.3 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KUM57660.1 - 0.096 11.0 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) GST_N_2 PF13409.6 KUM57661.1 - 1.3e-10 41.4 0.1 3.9e-10 39.9 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KUM57661.1 - 3.9e-09 36.7 0.0 7.6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KUM57661.1 - 1.9e-07 31.0 0.0 3.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KUM57661.1 - 2.5e-07 30.8 0.0 4.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KUM57661.1 - 1.4e-06 28.6 0.0 2.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KUM57661.1 - 7.5e-05 22.8 0.0 0.00017 21.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Abhydrolase_6 PF12697.7 KUM57663.1 - 0.027 15.1 0.0 0.03 14.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.25 KUM57664.1 - 0.0017 17.9 0.3 0.0024 17.4 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase OPT PF03169.15 KUM57665.1 - 1.8e-118 396.9 40.2 2.1e-118 396.7 40.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4231 PF14015.6 KUM57665.1 - 0.054 14.0 0.7 0.22 12.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2207 PF09972.9 KUM57665.1 - 0.19 10.5 1.7 0.55 8.9 1.7 1.9 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ank_2 PF12796.7 KUM57666.1 - 4.8e-59 196.9 13.1 2.5e-17 63.2 1.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM57666.1 - 3.1e-57 190.2 15.8 3.4e-10 40.3 0.0 7.9 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM57666.1 - 6.4e-37 125.1 9.8 2.3e-06 27.8 0.2 8.9 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 KUM57666.1 - 4.3e-35 118.6 18.8 9.9e-06 25.8 0.7 9.4 8 1 1 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 KUM57666.1 - 4.5e-31 103.4 8.1 0.0067 16.8 0.0 9.4 9 0 0 9 9 9 8 Ankyrin repeat Pedibin PF08182.11 KUM57666.1 - 0.078 12.8 0.5 3.6 7.5 0.0 3.5 3 0 0 3 3 3 0 Pedibin/Hym-346 family F_actin_cap_B PF01115.17 KUM57667.1 - 0.015 14.9 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 F-actin capping protein, beta subunit Holin_SPP1 PF04688.13 KUM57667.1 - 0.18 12.0 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 SPP1 phage holin Zn_clus PF00172.18 KUM57670.1 - 3.4e-09 36.7 7.4 6.7e-09 35.7 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM57670.1 - 0.015 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Catalase-rel PF06628.12 KUM57671.1 - 2e-09 37.5 0.0 3.1e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Catalase-related immune-responsive NmrA PF05368.13 KUM57673.1 - 5.4e-16 58.8 0.0 9.5e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM57673.1 - 1.1e-13 51.5 0.0 2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KUM57673.1 - 6.2e-07 29.7 0.0 1.4e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KUM57673.1 - 1.9e-05 24.3 0.0 3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.22 KUM57673.1 - 0.00024 21.9 0.0 0.00045 21.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KUM57673.1 - 0.00034 21.0 0.0 0.00074 19.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KUM57673.1 - 0.00042 20.4 0.3 0.0014 18.8 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 KUM57673.1 - 0.0079 15.4 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KUM57673.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 KUM57673.1 - 0.033 13.2 0.0 0.057 12.4 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KUM57673.1 - 0.042 13.9 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KUM57673.1 - 0.058 13.0 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.17 KUM57673.1 - 0.059 12.5 0.1 0.085 11.9 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_7 PF13241.6 KUM57673.1 - 0.1 13.1 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_4 PF07993.12 KUM57673.1 - 0.11 11.6 0.0 0.3 10.2 0.0 1.7 1 0 0 1 1 1 0 Male sterility protein adh_short PF00106.25 KUM57673.1 - 0.13 11.7 0.5 0.23 10.9 0.3 1.5 1 1 0 1 1 1 0 short chain dehydrogenase Lactamase_B PF00753.27 KUM57676.1 - 8.4e-07 29.2 1.5 5.9e-05 23.1 0.3 2.3 1 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KUM57676.1 - 0.0012 18.4 0.2 0.0042 16.6 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KUM57676.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain E1-E2_ATPase PF00122.20 KUM57677.1 - 7.8e-37 126.5 6.2 6.8e-36 123.5 0.1 3.7 3 2 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KUM57677.1 - 1.7e-17 64.4 0.0 4.1e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KUM57677.1 - 8.1e-11 41.5 0.1 3e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KUM57677.1 - 0.0052 16.6 0.1 0.0099 15.6 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KUM57677.1 - 0.026 14.6 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) GNVR PF13807.6 KUM57677.1 - 0.073 13.0 0.0 0.26 11.2 0.0 2.0 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase ABC1 PF03109.16 KUM57678.1 - 1.7e-20 73.4 0.2 9.9e-20 70.9 0.0 2.2 2 0 0 2 2 2 1 ABC1 family LRR_6 PF13516.6 KUM57679.1 - 1.1e-11 43.8 5.3 0.12 12.4 0.1 7.0 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 KUM57679.1 - 3.8e-05 24.0 8.9 0.28 11.7 0.0 4.7 6 0 0 6 6 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KUM57679.1 - 0.00013 21.7 4.3 0.17 11.6 0.3 4.4 3 2 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 KUM57679.1 - 0.0074 16.7 4.3 47 5.1 0.0 5.4 6 0 0 6 6 5 0 Leucine Rich Repeat SipA_VBS PF17985.1 KUM57679.1 - 0.071 13.0 1.2 20 5.3 0.2 3.1 3 0 0 3 3 3 0 SipA vinculin binding site Nop14 PF04147.12 KUM57679.1 - 0.69 8.1 20.6 0.91 7.7 20.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KUM57679.1 - 0.95 7.7 14.2 1.4 7.2 14.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KUM57679.1 - 2 7.8 21.1 2.8 7.3 21.1 1.2 1 0 0 1 1 1 0 SDA1 LKAAEAR PF15478.6 KUM57679.1 - 3 8.1 7.7 0.12 12.6 0.4 2.4 2 1 1 3 3 3 0 Family of unknown function with LKAAEAR motif BUD22 PF09073.10 KUM57679.1 - 3.5 6.9 18.6 5.1 6.3 18.6 1.2 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 KUM57679.1 - 4.7 6.4 13.5 6.6 6.0 13.5 1.3 1 0 0 1 1 1 0 NOA36 protein TFIIS_M PF07500.14 KUM57680.1 - 8.8e-28 97.0 0.0 1.9e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KUM57680.1 - 2.4e-18 65.7 4.7 4.4e-18 64.8 4.7 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KUM57680.1 - 2.9e-10 40.0 0.4 2.9e-10 40.0 0.4 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.8 KUM57680.1 - 0.024 14.3 1.3 0.054 13.2 0.1 2.1 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain ABC_transp_aux PF09822.9 KUM57680.1 - 0.097 12.1 0.3 0.15 11.5 0.3 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Alg6_Alg8 PF03155.15 KUM57681.1 - 1.9e-130 436.1 18.4 3.5e-129 431.9 18.4 2.1 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family COX17 PF05051.13 KUM57682.1 - 3.3e-21 75.4 7.1 6.3e-21 74.5 7.1 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KUM57682.1 - 0.0074 16.3 2.7 0.45 10.6 0.1 3.0 2 1 1 3 3 3 2 Cytochrome c oxidase biogenesis protein Cmc1 like RRM_1 PF00076.22 KUM57684.1 - 4.2e-45 151.4 0.0 2.9e-21 75.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KUM57684.1 - 2.7e-05 24.2 0.0 0.25 11.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 KUM57684.1 - 0.053 13.4 0.0 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif MRP-S33 PF08293.11 KUM57686.1 - 1.7e-29 101.9 0.0 1.9e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DUF382 PF04037.13 KUM57687.1 - 7.7e-60 200.6 1.1 1.8e-59 199.4 1.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 KUM57687.1 - 1.1e-19 70.0 2.0 1.1e-19 70.0 2.0 1.9 2 0 0 2 2 2 1 PSP ER_lumen_recept PF00810.18 KUM57688.1 - 1.7e-43 149.0 5.0 1.7e-43 149.0 5.0 1.6 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KUM57688.1 - 0.0018 18.0 6.9 0.26 11.1 0.3 2.9 3 0 0 3 3 3 2 PQ loop repeat Integrase_H2C2 PF17921.1 KUM57689.1 - 0.0028 17.7 0.3 0.0028 17.7 0.3 2.8 3 0 0 3 3 3 2 Integrase zinc binding domain XRCC4 PF06632.12 KUM57691.1 - 0.00035 19.6 15.0 0.00094 18.1 14.8 1.9 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Ribosomal_L38e PF01781.18 KUM57691.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L38e protein family DUF5572 PF17733.1 KUM57694.1 - 1.8e-23 82.1 0.2 3.6e-23 81.2 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) PUF PF00806.19 KUM57695.1 - 8.6e-34 113.3 3.4 3.6e-05 23.2 0.0 8.9 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat TPT PF03151.16 KUM57697.1 - 8.5e-60 202.5 13.0 1e-59 202.3 13.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KUM57697.1 - 2.6e-07 30.9 31.7 0.00033 20.8 10.7 2.9 2 1 0 2 2 2 2 EamA-like transporter family PSII PF00421.19 KUM57697.1 - 0.014 14.1 0.0 0.024 13.3 0.0 1.3 1 0 0 1 1 1 0 Photosystem II protein Ribonuclease_3 PF00636.26 KUM57698.1 - 7.5e-15 55.4 0.0 1.8e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KUM57698.1 - 1.4e-12 47.8 0.0 3.1e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KUM57698.1 - 0.15 12.8 1.0 0.5 11.1 0.1 2.3 3 0 0 3 3 3 0 Double-stranded RNA binding motif p450 PF00067.22 KUM57700.1 - 8.7e-28 97.3 0.0 1.4e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GRDP-like PF07173.12 KUM57701.1 - 7.9e-18 65.5 0.7 1.1e-12 48.8 0.1 2.9 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Fungal_trans PF04082.18 KUM57702.1 - 1.3e-09 37.5 0.5 2.1e-09 36.8 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM57702.1 - 1.2e-05 25.3 9.8 1.2e-05 25.3 9.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KUM57703.1 - 0.4 11.2 2.5 0.99 10.0 2.5 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Pkinase PF00069.25 KUM57704.1 - 3.2e-73 246.3 0.0 4.9e-73 245.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM57704.1 - 4.1e-36 124.6 0.0 9.6e-36 123.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KUM57704.1 - 0.01 15.8 0.0 1.9 8.3 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KUM57704.1 - 0.01 15.2 0.5 6.5 6.0 0.0 3.3 3 0 0 3 3 3 0 Kinase-like Pkinase_fungal PF17667.1 KUM57704.1 - 0.016 14.0 0.0 0.061 12.1 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 KUM57704.1 - 0.043 13.2 0.1 0.11 11.8 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 KUM57705.1 - 5e-29 101.3 40.5 1.4e-18 66.9 28.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM57705.1 - 7.3e-21 74.5 16.9 1.2e-20 73.9 16.9 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter API5 PF05918.11 KUM57706.1 - 0.24 10.2 0.5 0.28 9.9 0.5 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Peptidase_S10 PF00450.22 KUM57708.1 - 8.2e-92 308.8 0.0 1.1e-91 308.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pyr_redox_2 PF07992.14 KUM57709.1 - 8.8e-12 44.8 0.0 3.3e-08 33.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM57709.1 - 0.0094 15.6 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KUM57709.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KUM57709.1 - 0.17 10.9 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Lactamase_B PF00753.27 KUM57710.1 - 1.3e-13 51.4 1.7 1.7e-10 41.2 0.3 2.6 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KUM57710.1 - 0.00023 20.7 0.1 0.00041 19.9 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_hydro_6 PF01341.17 KUM57711.1 - 2.5e-106 355.9 2.5 3.1e-106 355.5 2.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Ubie_methyltran PF01209.18 KUM57711.1 - 0.2 11.0 0.0 0.4 10.0 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Amino_oxidase PF01593.24 KUM57713.1 - 1.4e-55 189.4 0.0 1.9e-55 189.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.21 KUM57713.1 - 7.5e-14 51.8 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.6 KUM57713.1 - 3.8e-13 49.4 0.7 9.2e-13 48.2 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KUM57713.1 - 6.9e-09 35.3 1.8 1e-08 34.7 1.8 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KUM57713.1 - 1e-07 31.9 0.1 2e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KUM57713.1 - 2.9e-07 30.2 0.1 3.9e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KUM57713.1 - 5.7e-07 28.9 0.7 5.7e-05 22.3 0.7 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KUM57713.1 - 4.6e-06 26.0 1.8 8.1e-06 25.2 1.8 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KUM57713.1 - 1.3e-05 24.1 0.7 7e-05 21.7 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KUM57713.1 - 3.4e-05 23.3 0.2 5.7e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KUM57713.1 - 0.00015 21.1 0.2 0.00031 20.1 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KUM57713.1 - 0.0023 17.1 2.0 0.0049 16.0 2.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KUM57713.1 - 0.0053 16.1 1.8 0.037 13.3 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KUM57713.1 - 0.034 13.5 3.7 0.047 13.0 0.9 2.2 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KUM57713.1 - 0.075 13.6 0.8 0.17 12.5 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase XRCC1_N PF01834.16 KUM57713.1 - 0.17 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 XRCC1 N terminal domain Abhydrolase_6 PF12697.7 KUM57714.1 - 8.9e-05 23.2 0.7 0.0001 23.0 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KUM57714.1 - 0.0062 16.4 1.2 0.07 13.0 1.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM57714.1 - 0.023 14.0 0.0 0.055 12.7 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 KUM57714.1 - 0.024 14.2 0.2 0.061 12.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 KUM57714.1 - 0.035 13.7 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold HMG-CoA_red PF00368.18 KUM57715.1 - 9.4e-134 446.0 3.0 1.2e-133 445.7 3.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 KUM57715.1 - 4e-14 52.7 3.5 2.5e-13 50.1 3.5 2.1 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KUM57715.1 - 5.4e-09 34.7 0.7 5.4e-09 34.7 0.7 1.3 2 0 0 2 2 2 1 Patched family HPIH PF13323.6 KUM57715.1 - 0.28 11.0 1.9 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain with HPIH motif CK_II_beta PF01214.18 KUM57716.1 - 3.5e-76 255.1 0.1 4.8e-76 254.6 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CxC5 PF18718.1 KUM57716.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases JAB PF01398.21 KUM57718.1 - 1.2e-09 38.2 0.5 4.2e-08 33.2 0.5 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Mito_carr PF00153.27 KUM57721.1 - 9.9e-42 140.8 2.8 2.1e-16 59.6 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein adh_short PF00106.25 KUM57722.1 - 1.2e-22 80.3 0.0 3.1e-16 59.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM57722.1 - 8.2e-11 41.9 0.0 5.1e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM57722.1 - 7e-06 26.1 0.2 1e-05 25.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KUM57722.1 - 5.2e-05 22.5 0.0 0.0026 17.0 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KUM57722.1 - 0.028 14.5 0.1 0.048 13.7 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TPP_enzyme_C PF02775.21 KUM57722.1 - 0.19 11.5 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain HSV_VP16_C PF12149.8 KUM57722.1 - 0.2 11.7 0.1 0.36 10.9 0.1 1.3 1 0 0 1 1 1 0 Herpes simplex virus virion protein 16 C terminal Fungal_trans_2 PF11951.8 KUM57723.1 - 0.0023 16.8 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SGL PF08450.12 KUM57724.1 - 2e-07 30.8 0.1 0.062 12.9 0.0 3.1 2 1 0 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region Oxidored_FMN PF00724.20 KUM57725.1 - 1.1e-34 120.3 0.0 1.5e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cupin_2 PF07883.11 KUM57726.1 - 0.00064 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain BNR_2 PF13088.6 KUM57727.1 - 4e-10 39.5 0.8 1.2e-07 31.3 0.3 2.9 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 KUM57727.1 - 1.3e-06 27.5 13.9 0.32 11.1 0.6 6.0 6 0 0 6 6 6 4 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KUM57727.1 - 0.0026 16.6 0.0 0.024 13.5 0.0 2.1 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, NCBP3 PF10309.9 KUM57727.1 - 0.054 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 Pyr_redox_2 PF07992.14 KUM57728.1 - 1.1e-31 110.2 0.0 1.5e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM57728.1 - 1.2e-13 51.4 0.1 1.3e-10 41.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM57728.1 - 4e-08 32.9 0.0 8.8e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM57728.1 - 1.5e-07 31.3 0.1 0.11 12.0 0.1 4.2 3 1 1 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.6 KUM57728.1 - 1.3e-06 27.8 0.1 3.9e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KUM57728.1 - 2.7e-06 27.4 0.6 0.38 10.7 0.0 4.1 3 1 1 4 4 4 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KUM57728.1 - 3.7e-06 27.3 0.0 0.00025 21.4 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KUM57728.1 - 1.8e-05 24.9 0.0 0.04 14.2 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KUM57728.1 - 0.0002 21.6 0.4 0.099 12.9 0.0 3.5 4 0 0 4 4 4 1 TrkA-N domain Trp_halogenase PF04820.14 KUM57728.1 - 0.00029 19.8 0.1 0.091 11.6 0.0 2.4 2 1 0 2 2 2 2 Tryptophan halogenase DUF1188 PF06690.11 KUM57728.1 - 0.036 13.6 0.0 7.8 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) ApbA PF02558.16 KUM57728.1 - 0.093 12.4 0.1 0.4 10.3 0.1 2.2 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KUM57728.1 - 0.11 11.5 0.0 0.34 9.9 0.0 1.8 3 0 0 3 3 3 0 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 KUM57728.1 - 0.12 12.6 0.1 16 5.8 0.0 2.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Fungal_trans PF04082.18 KUM57729.1 - 4.3e-23 81.7 0.3 8.2e-23 80.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM57729.1 - 0.019 15.1 0.5 0.037 14.2 0.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.18 KUM57730.1 - 1.6e-08 34.2 4.5 3.4e-08 33.1 4.5 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ALIX_LYPXL_bnd PF13949.6 KUM57730.1 - 0.0047 16.3 2.1 0.0067 15.8 2.1 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Glyco_hydro_72 PF03198.14 KUM57731.1 - 1.5e-130 435.1 8.9 2e-130 434.7 8.9 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KUM57731.1 - 8.8e-25 87.2 6.2 8.8e-25 87.2 6.2 2.3 2 0 0 2 2 2 1 X8 domain DUF2406 PF10295.9 KUM57733.1 - 1.1e-23 83.7 0.3 1.6e-23 83.1 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) CoA_transf_3 PF02515.17 KUM57734.1 - 1.2e-107 360.2 0.0 1.4e-107 360.1 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III AlaDh_PNT_C PF01262.21 KUM57734.1 - 0.11 11.8 0.0 0.53 9.5 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain p450 PF00067.22 KUM57735.1 - 3.2e-51 174.5 0.0 4.4e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KUM57736.1 - 7.5e-08 32.4 10.6 1.1e-07 31.8 10.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM57736.1 - 1.6e-06 27.2 0.0 2.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PSI_integrin PF17205.3 KUM57736.1 - 1 9.2 9.2 0.14 11.9 2.8 2.2 1 1 1 2 2 2 0 Integrin plexin domain DUF3176 PF11374.8 KUM57737.1 - 9.9e-38 128.6 1.1 2.7e-37 127.3 1.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Cadherin_C_2 PF16492.5 KUM57737.1 - 1.1 10.0 3.4 11 6.8 0.1 3.1 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal p450 PF00067.22 KUM57739.1 - 2e-68 231.3 0.0 2.4e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_25 PF01755.17 KUM57740.1 - 4.4e-07 30.0 0.0 0.00063 19.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Sugar_tr PF00083.24 KUM57741.1 - 7.5e-92 308.5 23.4 9.1e-92 308.3 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM57741.1 - 3.3e-24 85.5 35.9 3.3e-24 85.5 35.9 2.3 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM57741.1 - 9.3e-05 21.0 3.9 9.3e-05 21.0 3.9 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 KUM57741.1 - 0.022 15.0 4.0 0.022 15.0 4.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) PDU_like PF15953.5 KUM57741.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative propanediol utilisation OppC_N PF12911.7 KUM57741.1 - 0.29 11.2 5.0 1.3 9.0 0.6 3.0 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C MFS_1 PF07690.16 KUM57743.1 - 1.5e-44 152.4 54.0 3.7e-44 151.1 51.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 KUM57744.1 - 1.7e-20 73.6 0.4 3.4e-12 46.3 0.2 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KUM57744.1 - 4e-05 23.4 0.3 5.4e-05 22.9 0.3 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KUM57744.1 - 5.7e-05 23.3 0.1 0.00022 21.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KUM57744.1 - 5.9e-05 22.3 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KUM57744.1 - 0.00038 19.8 0.1 0.00061 19.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM57744.1 - 0.00041 19.7 0.0 0.025 13.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KUM57744.1 - 0.0023 17.1 1.4 0.0041 16.2 0.0 2.0 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.14 KUM57744.1 - 0.0031 16.3 0.0 0.0044 15.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein PALP PF00291.25 KUM57744.1 - 0.0033 16.9 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IlvN PF07991.12 KUM57744.1 - 0.005 16.4 0.0 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KUM57744.1 - 0.0095 16.2 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Thi4 PF01946.17 KUM57744.1 - 0.029 13.6 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.23 KUM57744.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.27 KUM57744.1 - 0.18 12.4 0.0 0.6 10.7 0.0 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Response_reg PF00072.24 KUM57745.1 - 6.1e-24 84.4 0.1 1.4e-23 83.1 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KUM57745.1 - 1.4e-22 80.3 0.1 2.9e-22 79.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KUM57745.1 - 7e-10 38.8 0.0 1.9e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KUM57745.1 - 2e-05 24.8 0.0 5.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KUM57745.1 - 0.00044 20.5 0.1 0.0016 18.7 0.0 2.0 1 1 1 2 2 2 1 PAS fold PAS_7 PF12860.7 KUM57745.1 - 0.0077 16.4 0.0 0.29 11.3 0.0 3.1 2 1 0 2 2 2 1 PAS fold HATPase_c_5 PF14501.6 KUM57745.1 - 0.41 10.6 3.6 1.4 8.8 0.1 3.2 2 2 0 2 2 2 0 GHKL domain FAD_binding_3 PF01494.19 KUM57747.1 - 1.1e-20 74.2 0.0 2.3e-20 73.2 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KUM57747.1 - 2.4e-07 30.7 0.1 0.0009 18.9 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM57747.1 - 1.6e-06 27.6 0.0 1.2e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM57747.1 - 2.6e-06 27.9 0.2 1.4e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM57747.1 - 0.00036 20.7 0.1 0.018 15.2 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 KUM57747.1 - 0.0017 18.0 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF1188 PF06690.11 KUM57747.1 - 0.081 12.5 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) KRE1 PF17056.5 KUM57747.1 - 0.15 11.8 0.5 21 4.9 0.0 2.3 2 0 0 2 2 2 0 Killer toxin-resistance protein 1 TrkA_N PF02254.18 KUM57747.1 - 0.18 12.0 0.0 0.45 10.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Hexapep PF00132.24 KUM57748.1 - 9.6e-09 34.6 4.7 0.002 17.7 0.9 3.9 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KUM57748.1 - 5.3e-05 23.6 0.0 9.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KUM57748.1 - 0.00053 19.0 0.3 0.00092 18.3 0.3 1.4 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 KUM57748.1 - 0.0039 15.4 1.1 0.0054 14.9 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KUM57748.1 - 0.13 12.1 5.3 5.7 6.8 1.7 3.2 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase BetaGal_dom4_5 PF13364.6 KUM57750.1 - 4.6e-60 201.2 10.9 1.8e-34 118.7 0.1 3.0 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KUM57750.1 - 6.2e-58 195.6 1.4 6.2e-58 195.6 1.4 1.6 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KUM57750.1 - 1.7e-28 98.0 0.3 2.3e-27 94.4 0.1 2.4 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_35 PF01301.19 KUM57750.1 - 2.6e-19 70.0 0.2 2.6e-19 70.0 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 NmrA PF05368.13 KUM57751.1 - 6.8e-09 35.6 0.0 1.1e-08 34.9 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM57751.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 KUM57751.1 - 0.026 15.0 0.0 0.061 13.8 0.0 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Spt20 PF12090.8 KUM57752.1 - 2.2e-59 200.9 0.6 2.2e-59 200.9 0.6 6.5 4 1 1 5 5 5 1 Spt20 family zf-C2H2 PF00096.26 KUM57754.1 - 2.4e-07 30.8 16.0 0.00035 20.8 3.6 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KUM57754.1 - 0.00015 22.0 4.8 0.00015 22.0 4.8 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KUM57754.1 - 0.00025 21.6 8.9 0.0068 17.2 3.0 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KUM57754.1 - 0.0016 19.0 4.8 0.53 11.0 0.5 2.5 1 1 1 2 2 2 2 FOXP coiled-coil domain Sina PF03145.16 KUM57754.1 - 0.078 12.9 1.9 0.12 12.3 1.9 1.2 1 0 0 1 1 1 0 Seven in absentia protein family zf-C2H2_6 PF13912.6 KUM57754.1 - 2 8.5 11.8 3.1 7.9 0.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_hydro_35 PF01301.19 KUM57755.1 - 1.5e-57 195.6 0.1 1.8e-57 195.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Cellulase PF00150.18 KUM57755.1 - 3e-06 26.9 0.3 3.9e-06 26.5 0.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Amidohydro_2 PF04909.14 KUM57755.1 - 0.011 15.6 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase MFS_1 PF07690.16 KUM57756.1 - 5.1e-35 121.0 26.9 6.8e-35 120.6 26.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.18 KUM57758.1 - 5.7e-10 39.1 10.0 1.3e-09 38.0 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM57758.1 - 0.00024 20.0 0.2 0.00036 19.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_12 PF08242.12 KUM57759.1 - 5.7e-15 55.9 0.0 2.8e-14 53.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM57759.1 - 8.2e-13 48.9 0.0 2.6e-12 47.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM57759.1 - 3.9e-11 43.0 0.0 7.3e-11 42.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM57759.1 - 6.2e-11 42.8 0.0 2.4e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM57759.1 - 1e-06 28.6 0.0 3.4e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM57759.1 - 1.9e-06 27.4 0.0 4.1e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KUM57759.1 - 0.0014 18.5 0.0 0.39 10.5 0.0 2.4 2 0 0 2 2 2 2 Hypothetical methyltransferase DUF3419 PF11899.8 KUM57759.1 - 0.0029 16.8 0.0 0.0048 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_24 PF13578.6 KUM57759.1 - 0.0056 17.7 0.0 0.038 15.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KUM57759.1 - 0.0057 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 KUM57759.1 - 0.015 14.5 0.0 0.43 9.7 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_32 PF13679.6 KUM57759.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PIG-S PF10510.9 KUM57760.1 - 5.5e-187 622.7 0.1 6.3e-187 622.5 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein HlyIII PF03006.20 KUM57761.1 - 4.4e-61 206.5 23.7 5.4e-61 206.2 23.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Asr PF06392.11 KUM57761.1 - 0.0066 16.8 0.6 0.017 15.5 0.6 1.6 1 0 0 1 1 1 1 Acid shock protein repeat SPC12 PF06645.13 KUM57761.1 - 0.0073 16.4 0.4 0.0073 16.4 0.4 2.8 3 1 1 4 4 4 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Glycophorin_A PF01102.18 KUM57762.1 - 0.011 15.9 0.6 0.011 15.9 0.6 2.3 1 1 1 2 2 2 0 Glycophorin A PARM PF17061.5 KUM57762.1 - 0.2 11.8 23.9 0.37 10.9 23.9 1.4 1 0 0 1 1 1 0 PARM Apt1 PF10351.9 KUM57762.1 - 0.24 10.2 2.1 0.27 10.0 2.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Menin PF05053.13 KUM57762.1 - 1.4 7.2 7.0 1.9 6.8 7.0 1.0 1 0 0 1 1 1 0 Menin MaoC_dehydrat_N PF13452.6 KUM57763.1 - 0.0067 16.6 0.0 0.84 9.8 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Aldo_ket_red PF00248.21 KUM57764.1 - 2.2e-50 171.5 0.0 2.5e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MazG PF03819.17 KUM57764.1 - 0.1 12.8 0.3 8.4 6.7 0.1 2.5 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Polyketide_cyc PF03364.20 KUM57765.1 - 8e-23 81.1 0.0 2.8e-22 79.3 0.0 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KUM57765.1 - 0.0092 16.3 0.0 0.084 13.1 0.0 2.0 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Fungal_trans PF04082.18 KUM57766.1 - 5.3e-13 48.6 0.8 8.5e-13 47.9 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KUM57766.1 - 0.011 14.5 1.1 0.023 13.5 1.1 1.5 1 1 0 1 1 1 0 Fungal specific transcription factor domain ABC2_membrane PF01061.24 KUM57767.1 - 2.2e-37 128.5 20.9 4.3e-37 127.6 20.9 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KUM57767.1 - 6.4e-23 81.8 0.1 6.4e-23 81.8 0.1 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KUM57767.1 - 2e-05 24.6 0.0 0.18 11.6 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KUM57767.1 - 0.027 14.4 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 KUM57767.1 - 0.03 13.8 0.0 0.68 9.3 0.0 2.4 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KUM57767.1 - 0.056 13.2 0.2 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 KUM57767.1 - 0.077 12.1 28.6 0.0058 15.8 22.8 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein AAA_16 PF13191.6 KUM57767.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KUM57767.1 - 0.28 11.7 0.5 0.57 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AMP-binding PF00501.28 KUM57768.1 - 7.8e-62 209.2 0.0 1e-61 208.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM57768.1 - 0.00017 22.5 0.0 0.00032 21.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.21 KUM57769.1 - 4.3e-45 154.5 0.0 5.2e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KUM57769.1 - 6.3e-08 32.0 0.0 1.5e-07 30.7 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KUM57769.1 - 2.1e-05 23.3 0.0 3e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KUM57769.1 - 3.5e-05 23.2 0.0 5.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KUM57769.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.13 KUM57769.1 - 0.2 10.5 0.0 0.36 9.6 0.0 1.4 1 1 0 1 1 1 0 Allinase Sod_Fe_C PF02777.18 KUM57770.1 - 5.9e-17 61.7 0.2 1.9e-14 53.7 0.2 2.3 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KUM57770.1 - 0.048 14.1 0.1 0.08 13.4 0.1 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain FmiP_Thoc5 PF09766.9 KUM57771.1 - 2.9e-31 109.1 13.4 3.5e-31 108.8 13.4 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SPATA1_C PF15743.5 KUM57771.1 - 0.0028 17.7 5.4 0.0092 16.1 2.4 2.2 2 0 0 2 2 2 1 Spermatogenesis-associated C-terminus VGPC1_C PF16799.5 KUM57771.1 - 0.053 13.5 5.6 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 RNase_E_G PF10150.9 KUM57771.1 - 0.098 12.1 5.8 1.3 8.4 1.6 2.1 2 0 0 2 2 2 0 Ribonuclease E/G family Rootletin PF15035.6 KUM57771.1 - 0.13 12.2 9.9 0.16 12.0 9.9 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4200 PF13863.6 KUM57771.1 - 0.24 11.8 15.0 0.66 10.4 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Casc1_N PF15927.5 KUM57771.1 - 1.3 8.7 11.9 0.17 11.6 7.7 1.7 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus YabA PF06156.13 KUM57771.1 - 1.6 9.4 6.5 15 6.3 0.1 2.3 2 0 0 2 2 2 0 Initiation control protein YabA FAD_binding_3 PF01494.19 KUM57773.1 - 4.2e-08 32.8 0.0 5.4e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KUM57773.1 - 0.009 15.1 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase TrkH PF02386.16 KUM57774.1 - 1.7e-121 406.2 2.6 2.1e-121 405.8 2.6 1.0 1 0 0 1 1 1 1 Cation transport protein Cupin_2 PF07883.11 KUM57775.1 - 3.7e-10 39.4 0.1 2e-08 33.8 0.1 2.7 3 0 0 3 3 3 1 Cupin domain Cupin_3 PF05899.12 KUM57775.1 - 0.003 17.2 0.0 0.97 9.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KUM57775.1 - 0.088 12.7 0.0 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_1 PF00190.22 KUM57775.1 - 0.13 11.9 0.4 2.6 7.7 0.1 2.8 3 1 1 4 4 4 0 Cupin Cupin_4 PF08007.12 KUM57775.1 - 0.14 11.6 0.1 0.14 11.6 0.1 1.5 2 0 0 2 2 2 0 Cupin superfamily protein GatD_N PF18195.1 KUM57775.1 - 0.15 11.4 0.0 0.94 8.8 0.0 2.2 2 0 0 2 2 2 0 GatD N-terminal domain Abhydrolase_3 PF07859.13 KUM57776.1 - 9.9e-12 45.2 0.0 7.8e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KUM57776.1 - 1.5e-08 34.4 0.0 2.1e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 KUM57776.1 - 3.8e-06 26.0 0.0 7e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 KUM57776.1 - 0.00026 20.0 0.0 0.00047 19.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.12 KUM57776.1 - 0.00081 18.2 0.0 0.32 9.6 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Esterase PF00756.20 KUM57776.1 - 0.0011 18.7 0.1 0.018 14.7 0.1 2.1 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KUM57776.1 - 0.018 14.9 0.0 3.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 KUM57776.1 - 0.025 14.2 0.0 0.24 11.0 0.0 2.3 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KUM57776.1 - 0.049 14.2 0.0 0.063 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family MIF4G PF02854.19 KUM57778.1 - 6.1e-61 205.7 0.0 6.3e-35 120.7 0.0 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 KUM57778.1 - 1e-40 139.6 10.6 1e-40 139.6 10.6 3.2 4 0 0 4 4 4 1 Up-frameshift suppressor 2 SUN PF03856.13 KUM57781.1 - 2.4e-93 312.1 7.0 3.6e-93 311.5 7.0 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) SOG2 PF10428.9 KUM57781.1 - 0.0092 15.2 3.1 0.012 14.8 3.1 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein FSA_C PF10479.9 KUM57781.1 - 5.7 4.9 13.4 8.1 4.4 13.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SWI-SNF_Ssr4 PF08549.10 KUM57781.1 - 5.9 5.4 5.1 7.8 5.0 5.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Mg_trans_NIPA PF05653.14 KUM57783.1 - 4.6e-13 48.9 9.4 4.5e-08 32.6 2.2 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KUM57783.1 - 8e-06 26.1 0.5 8e-06 26.1 0.5 2.6 2 0 0 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 KUM57783.1 - 6.1e-05 22.4 1.4 6.1e-05 22.4 1.4 2.1 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport vATP-synt_E PF01991.18 KUM57784.1 - 1.7e-62 210.4 9.3 2e-62 210.2 9.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4288 PF14119.6 KUM57784.1 - 0.32 11.4 7.2 14 6.1 0.6 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4288) SEN1_N PF12726.7 KUM57785.1 - 3.5e-207 690.1 1.1 5e-207 689.7 1.1 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KUM57785.1 - 3.5e-75 253.2 1.1 3.5e-75 253.2 1.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KUM57785.1 - 4.5e-62 209.2 0.0 8.6e-62 208.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KUM57785.1 - 1.6e-09 37.8 0.2 2e-05 24.4 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KUM57785.1 - 1.8e-07 31.6 0.1 8.1e-07 29.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KUM57785.1 - 1e-06 28.7 0.2 0.04 13.7 0.1 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KUM57785.1 - 1.1e-06 28.4 0.0 3.9e-05 23.3 0.0 2.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain zf-CCHC PF00098.23 KUM57785.1 - 0.0044 17.0 2.1 0.0044 17.0 2.1 3.4 3 0 0 3 3 3 1 Zinc knuckle DUF2075 PF09848.9 KUM57785.1 - 0.0087 15.3 0.3 0.27 10.4 0.1 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KUM57785.1 - 0.014 14.4 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 KUM57785.1 - 0.022 14.6 0.3 0.056 13.2 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase zf-CCHC_3 PF13917.6 KUM57785.1 - 0.023 14.7 22.8 0.2 11.6 0.5 4.1 2 1 2 4 4 4 0 Zinc knuckle TPR_MLP1_2 PF07926.12 KUM57785.1 - 0.039 14.0 0.2 0.15 12.1 0.2 2.0 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA PF00004.29 KUM57785.1 - 0.087 13.2 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4164 PF13747.6 KUM57785.1 - 0.11 12.8 2.7 0.52 10.6 2.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Sigma54_activat PF00158.26 KUM57785.1 - 0.16 11.7 0.0 0.53 10.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Pyrid_oxidase_2 PF13883.6 KUM57786.1 - 3.8e-32 111.6 0.0 5.9e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PhoLip_ATPase_C PF16212.5 KUM57788.1 - 1.9e-80 270.3 24.7 1.9e-80 270.3 24.7 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KUM57788.1 - 5.8e-19 67.6 2.1 1.8e-18 66.0 2.1 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KUM57788.1 - 3e-12 46.4 0.0 1.3e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KUM57788.1 - 3.8e-09 37.1 6.9 4.3e-06 27.2 0.7 3.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KUM57788.1 - 0.0046 16.5 1.3 0.022 14.3 0.0 2.7 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KUM57788.1 - 0.044 13.5 0.5 0.12 12.1 0.5 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Transp_cyt_pur PF02133.15 KUM57789.1 - 2.2e-82 277.2 44.1 3e-81 273.5 44.1 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cyclin PF08613.11 KUM57790.1 - 5.8e-06 26.8 0.2 1.6e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KUM57790.1 - 0.0099 15.6 0.1 0.02 14.6 0.1 1.5 1 1 0 1 1 1 1 Cyclin, N-terminal domain SRF-TF PF00319.18 KUM57791.1 - 3.2e-21 74.6 0.1 4.7e-21 74.0 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Glyco_hydro_106 PF17132.4 KUM57792.1 - 4.7e-27 94.6 0.1 1.3e-26 93.1 0.1 1.6 1 1 0 1 1 1 1 alpha-L-rhamnosidase Glyco_hydro_2_N PF02837.18 KUM57792.1 - 5.4e-05 23.2 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4988 PF16378.5 KUM57792.1 - 0.067 12.9 0.1 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function Iso_dh PF00180.20 KUM57793.1 - 1.6e-84 284.0 0.0 2e-84 283.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WBS_methylT PF12589.8 KUM57794.1 - 2.3e-14 53.9 0.7 4.1e-14 53.1 0.7 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KUM57794.1 - 5e-11 43.1 0.0 8.4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM57794.1 - 6.9e-11 42.7 0.0 1.5e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM57794.1 - 2e-05 25.3 0.0 4.8e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM57794.1 - 7.9e-05 22.5 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KUM57794.1 - 0.00049 19.9 0.0 0.00082 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KUM57794.1 - 0.0073 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM57794.1 - 0.0079 15.6 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 KUM57794.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent CMAS PF02353.20 KUM57794.1 - 0.14 11.4 0.0 1.5 8.0 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Erv26 PF04148.13 KUM57795.1 - 1.4e-93 312.5 0.1 1.5e-93 312.3 0.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 COX1 PF00115.20 KUM57795.1 - 0.03 13.2 3.9 0.038 12.9 3.9 1.0 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I DUF1970 PF09301.10 KUM57795.1 - 0.087 13.1 0.6 0.31 11.3 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1970) DMRL_synthase PF00885.19 KUM57796.1 - 1.5e-57 193.4 0.0 1.8e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Proteasome PF00227.26 KUM57797.1 - 3.6e-46 157.0 0.4 4.6e-32 111.0 0.0 2.5 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.9 KUM57797.1 - 5.3e-12 45.2 1.0 6.3e-12 44.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5633 PF18656.1 KUM57797.1 - 1.4 8.8 7.5 0.39 10.7 2.5 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5633) Lar_restr_allev PF14354.6 KUM57798.1 - 0.0023 18.3 0.3 0.0057 17.0 0.3 1.7 1 0 0 1 1 1 1 Restriction alleviation protein Lar MCM_OB PF17207.3 KUM57798.1 - 0.089 12.6 0.3 0.12 12.2 0.3 1.2 1 0 0 1 1 1 0 MCM OB domain Zn-ribbon_8 PF09723.10 KUM57798.1 - 0.13 12.4 1.9 0.42 10.8 1.9 1.9 1 1 0 1 1 1 0 Zinc ribbon domain Ogr_Delta PF04606.12 KUM57798.1 - 0.6 10.1 6.3 0.54 10.3 0.4 2.8 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zf-ribbon_3 PF13248.6 KUM57798.1 - 8.1 6.0 8.4 2.3 7.8 0.5 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Chlorosome_CsmC PF11098.8 KUM57799.1 - 0.026 14.5 0.2 0.031 14.2 0.2 1.2 1 1 0 1 1 1 0 Chlorosome envelope protein C DUF4044 PF13253.6 KUM57799.1 - 0.12 11.9 0.9 0.17 11.4 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) ABC_tran PF00005.27 KUM57802.1 - 6.1e-47 159.6 0.0 3.7e-26 92.3 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KUM57802.1 - 1.1e-30 107.3 34.3 6.1e-27 95.0 17.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KUM57802.1 - 3.7e-11 42.9 0.2 0.00025 20.5 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KUM57802.1 - 7e-07 28.9 0.4 0.0015 18.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KUM57802.1 - 7.1e-07 29.3 2.6 0.0024 17.8 0.0 3.3 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KUM57802.1 - 1.2e-05 25.8 3.7 0.095 13.1 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KUM57802.1 - 0.00032 21.0 1.4 0.099 12.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KUM57802.1 - 0.00038 20.4 0.1 0.011 15.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KUM57802.1 - 0.00051 20.1 0.4 0.064 13.3 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KUM57802.1 - 0.003 17.7 0.1 1.1 9.5 0.1 3.3 2 2 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KUM57802.1 - 0.006 17.1 7.1 0.029 14.9 0.1 2.6 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KUM57802.1 - 0.023 14.9 0.4 13 6.1 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit T2SSE PF00437.20 KUM57802.1 - 0.025 13.7 1.0 0.18 10.9 0.0 2.3 2 1 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.19 KUM57802.1 - 0.029 14.0 0.5 0.097 12.3 0.0 2.1 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KUM57802.1 - 0.032 14.6 0.4 2.7 8.4 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KUM57802.1 - 0.035 13.8 0.6 3.3 7.4 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KUM57802.1 - 0.04 13.6 0.2 0.48 10.1 0.1 2.3 2 1 1 3 3 3 0 AAA ATPase domain DUF87 PF01935.17 KUM57802.1 - 0.17 11.9 0.6 7.4 6.6 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Spore_IV_A PF09547.10 KUM57802.1 - 0.18 10.7 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Dynamin_N PF00350.23 KUM57802.1 - 0.28 11.2 1.9 0.98 9.5 0.0 2.4 2 1 0 2 2 2 0 Dynamin family DUF1427 PF07235.11 KUM57802.1 - 1.1 9.2 3.3 0.79 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) NB-ARC PF00931.22 KUM57802.1 - 6.9 5.8 5.4 2 7.5 0.0 2.8 4 0 0 4 4 4 0 NB-ARC domain Aa_trans PF01490.18 KUM57803.1 - 5.1e-40 137.4 37.7 6.2e-40 137.2 37.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RhoGAP PF00620.27 KUM57804.1 - 5.2e-42 143.2 0.1 1.2e-41 142.1 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KUM57804.1 - 3.5e-15 56.4 0.0 7e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KUM57804.1 - 1.3e-05 25.5 0.0 3.4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KUM57804.1 - 0.013 15.8 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3450 PF11932.8 KUM57804.1 - 0.33 10.2 2.4 0.58 9.4 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SIS PF01380.22 KUM57805.1 - 1.3e-57 193.2 0.0 1.2e-30 106.0 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KUM57805.1 - 1.9e-17 63.7 0.0 3.7e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KUM57805.1 - 5.6e-11 42.4 0.0 1.3e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KUM57805.1 - 5.8e-05 22.1 0.0 9.6e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Holin_BhlA PF10960.8 KUM57805.1 - 0.099 12.6 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 BhlA holin family GATase_2 PF00310.21 KUM57805.1 - 0.12 11.0 0.0 0.44 9.2 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferases class-II Hemerythrin PF01814.23 KUM57806.1 - 2.8e-11 44.1 2.4 3.5e-11 43.8 2.4 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TPR_9 PF13371.6 KUM57806.1 - 0.11 12.6 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat SQS_PSY PF00494.19 KUM57807.1 - 2.2e-38 132.3 0.0 3.2e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF5383 PF17355.2 KUM57807.1 - 0.031 14.7 1.3 0.059 13.7 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Peroxin-22 PF12827.7 KUM57807.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family DUF417 PF04224.12 KUM57807.1 - 0.079 12.5 0.0 0.53 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF417 DUF2951 PF11166.8 KUM57807.1 - 0.22 11.8 2.4 1.7 8.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) LMP PF04778.12 KUM57807.1 - 4.2 7.3 7.7 39 4.1 0.1 3.2 2 1 0 2 2 2 0 LMP repeated region TauD PF02668.16 KUM57808.1 - 9.8e-52 176.4 0.5 1.1e-51 176.2 0.5 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cellulase PF00150.18 KUM57809.1 - 5.3e-16 58.9 0.2 6.6e-16 58.6 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KUM57809.1 - 0.00093 18.4 0.0 0.0018 17.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4038 PF13204.6 KUM57809.1 - 0.0067 16.1 0.1 0.01 15.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 KUM57809.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase DUF2255 PF10012.9 KUM57809.1 - 0.11 12.6 0.5 0.22 11.7 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) Acetyltransf_7 PF13508.7 KUM57810.1 - 1.4e-09 38.2 0.0 1.9e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM57810.1 - 8.6e-09 35.7 0.0 1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KUM57810.1 - 9.9e-09 35.2 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KUM57810.1 - 0.0042 17.0 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KUM57810.1 - 0.013 15.6 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase AA_permease_2 PF13520.6 KUM57811.1 - 1.1e-49 169.5 56.2 1.3e-49 169.2 56.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM57811.1 - 1.1e-26 93.5 48.0 1.4e-26 93.1 48.0 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.8 KUM57811.1 - 0.054 13.4 0.7 0.12 12.3 0.7 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) DUF3810 PF12725.7 KUM57811.1 - 0.64 9.3 0.0 0.64 9.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3810) His_Phos_2 PF00328.22 KUM57812.1 - 3.7e-41 141.8 0.0 4.4e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF2236 PF09995.9 KUM57813.1 - 1.6e-07 31.8 0.0 2.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DnaJ-X PF14308.6 KUM57815.1 - 9.9e-76 253.9 5.4 9.9e-76 253.9 5.4 3.4 3 2 1 4 4 4 1 X-domain of DnaJ-containing DnaJ PF00226.31 KUM57815.1 - 2.7e-25 88.2 0.2 9.7e-25 86.5 0.2 2.0 1 0 0 1 1 1 1 DnaJ domain MARVEL PF01284.23 KUM57816.1 - 1.3e-07 31.7 14.0 1.7e-07 31.4 14.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain Deltameth_res PF16020.5 KUM57816.1 - 0.86 9.5 0.0 0.86 9.5 0.0 3.3 4 0 0 4 4 4 0 Deltamethrin resistance AA_permease PF00324.21 KUM57817.1 - 3.3e-104 349.2 47.5 3.3e-104 349.2 47.5 2.8 2 1 0 2 2 2 1 Amino acid permease AA_permease_2 PF13520.6 KUM57817.1 - 2.4e-25 89.2 40.5 2.4e-25 89.2 40.5 2.1 2 0 0 2 2 2 1 Amino acid permease Peptidase_A4 PF01828.17 KUM57820.1 - 3.8e-64 216.0 8.2 4.5e-64 215.8 8.2 1.1 1 0 0 1 1 1 1 Peptidase A4 family CcdA PF07362.12 KUM57821.1 - 0.35 11.3 1.8 0.85 10.1 0.8 2.0 2 1 0 2 2 2 0 Post-segregation antitoxin CcdA SUZ PF12752.7 KUM57823.1 - 1.2e-05 25.9 2.7 1.2e-05 25.9 2.7 4.7 2 1 1 3 3 3 1 SUZ domain CwfJ_C_1 PF04677.15 KUM57826.1 - 1.2e-29 102.7 0.0 9.6e-29 99.7 0.0 2.1 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KUM57826.1 - 3.1e-29 101.8 0.1 9e-29 100.3 0.1 1.9 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 ATP_bind_1 PF03029.17 KUM57827.1 - 1.3e-72 244.5 0.0 1.8e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KUM57827.1 - 1.3e-05 24.9 0.0 0.0014 18.2 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KUM57827.1 - 0.00036 19.6 0.0 0.17 10.9 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KUM57827.1 - 0.00046 20.3 0.0 0.0044 17.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase PRK PF00485.18 KUM57827.1 - 0.00065 19.5 0.1 0.013 15.2 0.0 2.5 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 KUM57827.1 - 0.0018 17.8 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 KUM57827.1 - 0.0033 17.2 0.0 0.0076 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KUM57827.1 - 0.0043 16.7 0.0 0.023 14.3 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KUM57827.1 - 0.0044 17.3 0.0 0.016 15.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 KUM57827.1 - 0.0044 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KUM57827.1 - 0.0057 15.9 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KUM57827.1 - 0.0058 17.0 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 KUM57827.1 - 0.006 15.8 0.0 0.15 11.2 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_33 PF13671.6 KUM57827.1 - 0.0061 16.7 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 KUM57827.1 - 0.0071 15.9 0.0 0.24 10.9 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B cobW PF02492.19 KUM57827.1 - 0.011 15.3 0.0 1 8.9 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KUM57827.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KUM57827.1 - 0.014 14.9 0.0 5.7 6.4 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family Roc PF08477.13 KUM57827.1 - 0.016 15.4 0.0 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Methyltransf_32 PF13679.6 KUM57827.1 - 0.018 15.1 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RsgA_GTPase PF03193.16 KUM57827.1 - 0.029 14.3 0.0 9.7 6.1 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase CLP1_P PF16575.5 KUM57827.1 - 0.054 13.3 0.0 0.34 10.7 0.0 2.2 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PduV-EutP PF10662.9 KUM57827.1 - 0.1 12.3 0.1 0.88 9.3 0.0 2.4 3 1 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.14 KUM57827.1 - 0.14 11.3 0.1 0.31 10.2 0.1 1.8 1 1 0 1 1 1 0 KAP family P-loop domain Pox_A32 PF04665.12 KUM57827.1 - 0.16 11.4 0.1 0.95 8.9 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein 2-Hacid_dh_C PF02826.19 KUM57830.1 - 2.8e-59 199.4 0.0 3.8e-59 199.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KUM57830.1 - 1.8e-14 53.6 0.0 2.4e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KUM57830.1 - 0.00037 20.7 0.3 0.00056 20.1 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KUM57830.1 - 0.02 14.5 0.1 0.037 13.6 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KUM57830.1 - 0.073 13.7 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.25 KUM57831.1 - 1.9e-13 50.4 0.0 2.4e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM57831.1 - 3.9e-08 32.9 0.0 5.5e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Aldo_ket_red PF00248.21 KUM57832.1 - 9.8e-53 179.2 0.0 2.8e-52 177.8 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family zf-U1 PF06220.12 KUM57833.1 - 8.7e-06 25.4 0.1 1.5e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 U1 zinc finger Zn_clus PF00172.18 KUM57834.1 - 7.6e-08 32.4 8.8 7.6e-08 32.4 8.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAP_GLY PF01302.25 KUM57835.1 - 1.1e-18 67.0 0.3 2.1e-18 66.1 0.3 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KUM57835.1 - 1.1e-14 54.3 9.3 8.5e-05 22.8 0.3 5.0 3 1 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KUM57835.1 - 1.7e-09 37.3 11.5 0.00011 21.8 0.6 5.0 2 2 3 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 KUM57835.1 - 2.5e-06 27.1 1.0 0.014 14.9 0.1 3.8 1 1 3 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 KUM57835.1 - 1.7e-05 24.5 11.2 3.9 7.8 0.0 6.4 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 KUM57835.1 - 0.034 14.7 6.3 23 6.1 0.0 5.7 5 1 1 6 6 6 0 Leucine Rich Repeat SF3A2 PF16835.5 KUM57836.1 - 1.5e-35 121.4 0.1 2.5e-35 120.7 0.1 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KUM57836.1 - 3.5e-06 27.2 1.9 2.5e-05 24.5 0.5 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 KUM57836.1 - 0.057 13.0 1.5 0.13 11.8 1.5 1.7 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pkinase PF00069.25 KUM57837.1 - 1.5e-54 185.2 0.0 2.2e-53 181.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM57837.1 - 8.6e-25 87.5 0.5 2.2e-19 69.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KUM57837.1 - 4e-06 26.0 0.1 5.6e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KUM57837.1 - 0.00019 21.5 1.6 0.012 15.6 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KUM57837.1 - 0.00029 20.2 0.0 0.00064 19.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KUM57837.1 - 0.00051 19.4 0.3 0.0012 18.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KUM57837.1 - 0.0053 15.9 0.1 0.012 14.6 0.0 1.5 2 0 0 2 2 2 1 Seadornavirus VP7 NFACT-C PF11923.8 KUM57837.1 - 0.02 14.8 0.2 0.045 13.7 0.2 1.6 1 0 0 1 1 1 0 NFACT protein C-terminal domain FTA2 PF13095.6 KUM57837.1 - 0.026 14.1 0.1 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KUM57837.1 - 0.066 12.0 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase TFIIA PF03153.13 KUM57837.1 - 0.36 10.8 10.2 0.57 10.1 10.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GST_N_3 PF13417.6 KUM57838.1 - 1.3e-20 73.6 0.0 2.6e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KUM57838.1 - 3.4e-18 65.7 0.0 6.3e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KUM57838.1 - 2.2e-09 37.5 0.0 4.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KUM57838.1 - 8e-06 25.8 0.0 1.8e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KUM57838.1 - 0.00035 21.1 0.0 0.00067 20.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KUM57838.1 - 0.0026 17.9 0.1 0.026 14.7 0.0 2.6 3 0 0 3 3 3 1 Glutaredoxin GST_C PF00043.25 KUM57838.1 - 0.0055 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KUM57838.1 - 0.015 15.4 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Elongin_A PF06881.11 KUM57838.1 - 0.25 11.9 3.3 6.8 7.3 0.1 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF4880 PF16220.5 KUM57838.1 - 0.27 11.1 1.6 0.56 10.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) Dioxygenase_C PF00775.21 KUM57840.1 - 1.4e-06 27.9 0.2 3.4e-06 26.6 0.2 1.7 1 1 0 1 1 1 1 Dioxygenase Glyco_hydro_3_C PF01915.22 KUM57842.1 - 1e-45 156.2 0.0 1.8e-45 155.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KUM57842.1 - 3.1e-36 125.4 0.0 5e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KUM57842.1 - 1.6e-21 76.2 0.1 3.3e-21 75.2 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar_tr PF00083.24 KUM57843.1 - 9.3e-131 436.8 27.2 1.1e-130 436.6 27.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM57843.1 - 1.2e-24 86.9 56.3 2.4e-21 76.1 30.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM57843.1 - 0.074 11.5 8.5 0.011 14.2 2.1 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) K_oxygenase PF13434.6 KUM57844.1 - 1.4e-09 37.6 0.0 2.7e-05 23.5 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KUM57844.1 - 5.4e-08 31.7 0.0 1.6e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KUM57844.1 - 3.5e-07 29.8 0.0 4.3e-06 26.2 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM57844.1 - 3e-05 24.1 0.3 0.02 14.9 0.1 3.5 2 1 1 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KUM57844.1 - 0.00011 22.4 0.4 0.0018 18.5 0.1 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KUM57844.1 - 0.00018 20.9 0.0 0.0044 16.3 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM57844.1 - 0.0021 17.7 0.7 2.8 7.4 0.0 2.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KUM57844.1 - 0.0041 17.2 0.0 0.22 11.6 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KUM57844.1 - 0.012 15.0 0.0 0.036 13.4 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AA_permease_2 PF13520.6 KUM57846.1 - 2.7e-46 158.3 49.7 2e-35 122.4 19.7 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KUM57846.1 - 5.5e-13 48.3 36.3 5.1e-11 41.8 14.9 2.1 2 0 0 2 2 2 2 Amino acid permease adh_short_C2 PF13561.6 KUM57848.1 - 6.5e-60 202.6 0.1 7.6e-60 202.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM57848.1 - 4.6e-40 137.2 0.1 5.5e-40 136.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM57848.1 - 1.1e-08 35.2 0.3 1.8e-08 34.5 0.3 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KUM57848.1 - 0.0011 18.8 0.1 0.0022 17.9 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KUM57848.1 - 0.0033 18.1 0.0 0.0059 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain THF_DHG_CYH_C PF02882.19 KUM57848.1 - 0.014 14.7 0.1 0.044 13.1 0.1 1.8 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 KUM57848.1 - 0.037 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KUM57848.1 - 0.063 12.7 0.0 0.088 12.3 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RecC_C PF17946.1 KUM57848.1 - 0.081 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 RecC C-terminal domain Methyltransf_12 PF08242.12 KUM57848.1 - 0.089 13.5 0.0 0.18 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Gln-synt_C PF00120.24 KUM57849.1 - 2.7e-09 36.5 0.0 3.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_C PF00120.24 KUM57850.1 - 6e-50 170.2 0.0 7e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Malate_synthase PF01274.22 KUM57851.1 - 8e-231 766.8 0.0 9.2e-231 766.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase LPMO_10 PF03067.15 KUM57852.1 - 4.5e-12 47.0 2.7 8.4e-12 46.1 2.7 1.5 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Zn_ribbon_recom PF13408.6 KUM57855.1 - 0.73 10.4 6.2 2 9.0 6.2 1.7 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain NmrA PF05368.13 KUM57856.1 - 2.9e-14 53.2 0.0 3.9e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM57856.1 - 3.6e-13 49.8 0.0 5.5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Methyltransf_12 PF08242.12 KUM57856.1 - 0.029 15.1 0.0 0.064 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.18 KUM57856.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_11 PF08241.12 KUM57856.1 - 0.17 12.6 0.0 0.39 11.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cupin_7 PF12973.7 KUM57857.1 - 7.7e-13 48.2 0.1 1.1e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain Chitin_bind_4 PF00379.23 KUM57857.1 - 0.11 13.1 0.9 0.46 11.0 0.1 2.4 3 0 0 3 3 3 0 Insect cuticle protein Glyco_hydro_75 PF07335.11 KUM57859.1 - 7.9e-44 149.8 0.1 1.3e-43 149.1 0.1 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 EB PF01683.18 KUM57859.1 - 0.61 10.4 14.4 0.37 11.1 9.8 2.2 2 0 0 2 2 2 0 EB module Pkinase PF00069.25 KUM57860.1 - 3.2e-63 213.6 0.0 4.2e-63 213.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM57860.1 - 4.2e-33 114.7 0.0 5.5e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM57860.1 - 7.3e-07 28.8 0.0 1.1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KUM57860.1 - 0.00075 19.5 1.7 0.0015 18.5 0.2 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KUM57860.1 - 0.0034 16.8 0.1 0.0062 15.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KUM57860.1 - 0.012 14.4 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KUM57860.1 - 0.029 13.3 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF19 PF01579.18 KUM57861.1 - 0.031 14.1 0.4 0.031 14.1 0.4 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF19) Metallophos PF00149.28 KUM57863.1 - 6.4e-10 39.9 0.0 1.2e-09 38.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KUM57863.1 - 5.1e-06 26.8 0.4 5.6e-05 23.4 0.7 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain ADH_zinc_N PF00107.26 KUM57864.1 - 3e-27 95.2 0.5 4.4e-27 94.6 0.5 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM57864.1 - 8.6e-18 65.7 0.0 1.6e-17 64.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM57864.1 - 2.4e-10 40.3 0.1 9.2e-10 38.4 0.1 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KUM57864.1 - 0.0011 18.3 0.6 0.0017 17.7 0.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CMAS PF02353.20 KUM57864.1 - 0.037 13.3 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TrkA_N PF02254.18 KUM57864.1 - 0.041 14.1 0.0 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 KUM57864.1 - 0.043 13.2 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 KUM57864.1 - 0.057 13.1 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_N_2 PF16884.5 KUM57864.1 - 0.1 12.5 0.3 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Fungal_trans PF04082.18 KUM57865.1 - 0.0015 17.6 2.1 0.045 12.8 0.4 2.7 1 1 0 2 2 2 2 Fungal specific transcription factor domain Kdo PF06293.14 KUM57866.1 - 6.2e-06 25.7 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KUM57866.1 - 0.0079 16.1 0.8 0.16 11.9 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KUM57866.1 - 0.098 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase SPX PF03105.19 KUM57866.1 - 0.1 12.5 4.5 0.17 11.8 4.5 1.3 1 0 0 1 1 1 0 SPX domain Aa_trans PF01490.18 KUM57867.1 - 9.5e-34 116.8 32.4 5.8e-20 71.4 15.5 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein AMP-binding PF00501.28 KUM57868.1 - 3.8e-84 282.7 0.0 7.8e-84 281.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KUM57868.1 - 1.5e-69 234.9 0.4 2.5e-69 234.1 0.4 1.2 1 0 0 1 1 1 1 Condensation domain ketoacyl-synt PF00109.26 KUM57868.1 - 2.4e-68 230.5 0.2 8.2e-68 228.7 0.0 2.2 3 0 0 3 3 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KUM57868.1 - 1.1e-52 178.6 0.5 5.9e-52 176.2 0.0 2.5 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KUM57868.1 - 1.9e-48 165.2 0.1 4.1e-48 164.1 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KUM57868.1 - 7.9e-47 160.3 0.0 2e-46 159.0 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KUM57868.1 - 3.3e-29 101.3 0.0 2.4e-28 98.5 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KUM57868.1 - 5.6e-24 84.7 0.0 3.6e-22 78.8 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 KUM57868.1 - 2.3e-21 76.4 0.0 8.2e-21 74.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KUM57868.1 - 1e-16 61.4 0.0 3.1e-16 59.8 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KUM57868.1 - 1.2e-15 57.6 0.4 1.6e-06 28.3 0.0 3.2 3 0 0 3 3 2 2 Phosphopantetheine attachment site adh_short PF00106.25 KUM57868.1 - 5.8e-14 52.0 0.2 2.6e-12 46.6 0.0 3.1 3 0 0 3 3 3 1 short chain dehydrogenase Epimerase PF01370.21 KUM57868.1 - 1.9e-12 47.2 0.0 1.6e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 KUM57868.1 - 2.4e-11 44.2 0.0 5.2e-10 39.9 0.0 3.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM57868.1 - 2.5e-10 40.3 0.0 8.8e-10 38.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM57868.1 - 4.7e-09 36.3 0.0 1.4e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM57868.1 - 9.5e-09 35.8 0.0 6.1e-08 33.2 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KUM57868.1 - 2.8e-07 30.3 0.7 1.6e-06 27.9 0.0 2.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase AMP-binding_C PF13193.6 KUM57868.1 - 2.6e-06 28.3 0.3 8e-06 26.7 0.0 2.1 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain Ubie_methyltran PF01209.18 KUM57868.1 - 7.8e-06 25.4 0.1 1.5e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.19 KUM57868.1 - 1.4e-05 24.2 0.0 7.7e-05 21.8 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.23 KUM57868.1 - 1.8e-05 24.2 0.1 3.8e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain RmlD_sub_bind PF04321.17 KUM57868.1 - 0.0025 16.9 0.0 0.0073 15.4 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain UPF0176_N PF17773.1 KUM57868.1 - 0.023 15.1 0.1 0.07 13.5 0.1 1.8 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain Methyltransf_16 PF10294.9 KUM57868.1 - 0.029 14.1 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Sacchrp_dh_NADP PF03435.18 KUM57868.1 - 0.059 13.6 0.1 3.1 8.1 0.0 3.3 3 0 0 3 3 2 0 Saccharopine dehydrogenase NADP binding domain Glyco_hydro_42M PF08532.10 KUM57868.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain ADH_N PF08240.12 KUM57869.1 - 4e-05 23.5 0.0 0.0014 18.5 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM57869.1 - 0.0016 18.4 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KUM57869.1 - 0.0023 17.8 0.1 0.0054 16.6 0.0 1.6 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase p450 PF00067.22 KUM57870.1 - 2.8e-34 118.7 0.0 3.6e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KUM57871.1 - 8.9e-29 100.5 0.0 1.8e-28 99.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 B56 PF01603.20 KUM57872.1 - 3.5e-192 638.9 4.1 4.2e-192 638.7 4.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KUM57872.1 - 0.0046 16.9 0.9 0.81 9.6 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF810 PF05664.11 KUM57872.1 - 0.14 10.6 0.0 0.26 9.8 0.0 1.3 1 0 0 1 1 1 0 Plant family of unknown function (DUF810) Centro_C10orf90 PF17730.1 KUM57873.1 - 0.096 11.5 0.0 0.096 11.5 0.0 1.1 1 0 0 1 1 1 0 Centrosomal C10orf90 TPR_2 PF07719.17 KUM57876.1 - 2.5e-28 95.9 8.8 0.0039 17.2 0.0 10.6 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 KUM57876.1 - 6.3e-28 95.4 0.1 0.00044 19.9 0.3 10.0 9 0 0 9 9 9 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM57876.1 - 3.4e-27 94.5 13.1 1.1e-21 76.8 0.9 5.5 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KUM57876.1 - 6.4e-21 74.6 7.9 0.00045 20.7 0.0 7.7 6 2 1 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 KUM57876.1 - 3.3e-15 56.1 23.6 1.9e-05 24.9 0.3 9.9 7 4 2 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KUM57876.1 - 1.7e-14 52.7 0.1 0.53 10.6 0.1 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KUM57876.1 - 1.3e-13 50.5 14.7 2.4 9.2 0.3 10.4 8 3 3 11 11 10 1 Tetratricopeptide repeat TPR_16 PF13432.6 KUM57876.1 - 6.3e-12 45.9 19.8 0.51 11.0 1.3 9.1 8 1 2 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 KUM57876.1 - 9e-11 41.3 0.9 0.38 10.5 0.1 8.4 9 0 0 9 9 9 2 TPR repeat TPR_6 PF13174.6 KUM57876.1 - 1.2e-08 35.0 7.9 1.4 9.7 0.2 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KUM57876.1 - 4.8e-08 32.5 17.4 0.14 12.2 0.1 9.8 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_10 PF13374.6 KUM57876.1 - 1e-06 28.4 21.6 0.0016 18.3 0.0 8.7 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 KUM57876.1 - 9.7e-05 22.5 0.8 5 7.7 0.0 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KUM57876.1 - 0.00024 20.6 7.6 0.15 11.4 1.3 3.8 4 1 0 4 4 4 2 MalT-like TPR region TPR_21 PF09976.9 KUM57876.1 - 0.0023 17.7 2.1 6.9 6.3 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat-like domain SRP_TPR_like PF17004.5 KUM57876.1 - 0.0025 17.8 0.1 0.068 13.2 0.0 2.7 2 0 0 2 2 2 1 Putative TPR-like repeat TPR_4 PF07721.14 KUM57876.1 - 0.0078 16.7 17.4 18 6.4 0.1 8.0 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 KUM57876.1 - 0.29 11.3 13.4 17 5.7 0.1 6.4 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 KUM57876.1 - 3.1 7.9 5.9 13 5.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF572 PF04502.13 KUM57877.1 - 3.1e-64 217.7 19.3 4.5e-64 217.2 19.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) Rap1_C PF11626.8 KUM57877.1 - 0.12 12.4 1.1 0.33 11.1 0.1 2.3 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain TniQ PF06527.11 KUM57877.1 - 0.35 11.6 3.1 3.3 8.5 0.0 2.7 2 1 0 2 2 2 0 TniQ SSP160 PF06933.11 KUM57877.1 - 0.96 7.6 15.5 1.7 6.8 15.5 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FAT PF02259.23 KUM57878.1 - 4.4e-73 246.5 9.8 1.5e-72 244.7 8.9 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KUM57878.1 - 1e-34 120.5 0.1 2.4e-34 119.3 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KUM57878.1 - 1.7e-05 24.6 0.1 4.9e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 FATC domain FANCI_S2 PF14676.6 KUM57878.1 - 0.14 12.4 0.3 4.7 7.5 0.0 3.8 4 0 0 4 4 4 0 FANCI solenoid 2 Pkinase PF00069.25 KUM57879.1 - 0.00024 20.6 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM57879.1 - 0.028 13.7 0.0 0.061 12.6 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Tau95 PF09734.9 KUM57881.1 - 6.5e-40 137.2 0.9 9e-40 136.7 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KUM57881.1 - 6e-37 126.7 0.1 9.4e-37 126.0 0.1 1.3 1 0 0 1 1 1 1 Tau95 Triple barrel domain Cyclin_N PF00134.23 KUM57882.1 - 6.7e-36 122.8 0.2 6.7e-36 122.8 0.2 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KUM57882.1 - 2.4e-13 50.2 1.6 6.6e-13 48.8 1.6 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain DSPc PF00782.20 KUM57883.1 - 2.8e-23 82.2 0.0 1e-20 73.9 0.0 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KUM57883.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Methyltransf_31 PF13847.6 KUM57884.1 - 1.6e-12 47.5 0.0 2.4e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KUM57884.1 - 1.5e-10 41.2 0.0 2.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM57884.1 - 8e-08 32.9 0.0 1.8e-06 28.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM57884.1 - 1.4e-07 32.1 0.0 9.9e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KUM57884.1 - 1.3e-05 25.9 0.9 4.7e-05 24.0 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 KUM57884.1 - 0.00021 21.3 0.1 0.00041 20.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KUM57884.1 - 0.0019 18.3 0.0 0.0028 17.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KUM57884.1 - 0.005 16.4 0.0 0.009 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KUM57884.1 - 0.0061 16.2 0.0 0.015 14.9 0.0 1.5 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KUM57884.1 - 0.034 13.9 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pox_MCEL PF03291.16 KUM57884.1 - 0.14 11.2 0.0 0.36 9.9 0.0 1.6 2 0 0 2 2 2 0 mRNA capping enzyme NESP55 PF06390.12 KUM57884.1 - 0.42 10.2 14.5 0.2 11.3 8.5 2.1 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) FAM176 PF14851.6 KUM57884.1 - 1.3 8.7 7.6 2.7 7.6 2.8 2.2 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 KUM57884.1 - 1.4 9.3 10.7 7.5 7.0 0.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain AIM3 PF17096.5 KUM57884.1 - 7.9 7.5 7.6 5.9 7.9 0.5 2.3 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Methyltransf_16 PF10294.9 KUM57885.1 - 0.002 17.9 0.0 0.0024 17.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase WD40 PF00400.32 KUM57886.1 - 9.7e-13 48.4 3.1 3.2 8.8 0.0 8.4 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM57886.1 - 9e-08 32.3 0.1 0.16 12.3 0.0 6.3 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KUM57886.1 - 0.00017 21.3 0.2 1.4 8.4 0.0 3.8 2 1 1 3 3 3 3 PQQ-like domain Ge1_WD40 PF16529.5 KUM57886.1 - 0.034 13.1 0.0 0.18 10.7 0.0 2.1 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ADH_N PF08240.12 KUM57887.1 - 1.6e-28 98.8 1.9 1.6e-28 98.8 1.9 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Yippee-Mis18 PF03226.14 KUM57887.1 - 1.2e-18 67.2 0.7 2.1e-18 66.4 0.1 1.7 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ADH_zinc_N PF00107.26 KUM57887.1 - 1.5e-17 63.8 0.0 3.1e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KUM57887.1 - 0.00031 20.6 0.3 0.00091 19.1 0.3 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 KUM57887.1 - 0.00081 20.5 0.0 0.0023 19.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KUM57887.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus RIG-I_C-RD PF11648.8 KUM57887.1 - 1.8 8.8 4.6 0.44 10.8 1.0 1.8 2 0 0 2 2 2 0 C-terminal domain of RIG-I KH_1 PF00013.29 KUM57888.1 - 8.8e-41 137.6 9.2 1.8e-16 59.7 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KUM57888.1 - 4.6e-09 36.0 11.0 0.0052 16.6 0.7 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KUM57888.1 - 4.4e-08 32.9 5.2 0.033 14.1 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KUM57888.1 - 0.00021 21.3 5.1 0.42 10.7 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain GARS_C PF02843.16 KUM57888.1 - 0.0025 18.0 0.5 0.16 12.3 0.0 2.7 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, C domain DUF5350 PF17299.2 KUM57889.1 - 1.2 9.6 3.4 22 5.6 0.8 3.2 2 1 0 2 2 2 0 Family of unknown function (DUF5350) cNMP_binding PF00027.29 KUM57890.1 - 4e-16 58.8 0.0 5.1e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain RTT107_BRCT_5 PF16770.5 KUM57891.1 - 3.7e-35 119.8 0.0 2.9e-31 107.3 0.0 4.3 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KUM57891.1 - 1.4e-32 111.4 2.4 3.9e-20 71.6 0.4 6.0 6 1 0 6 6 6 4 twin BRCT domain BRCT PF00533.26 KUM57891.1 - 4.6e-28 97.4 0.0 6.2e-09 36.1 0.0 6.6 6 2 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KUM57891.1 - 1.4e-25 89.5 0.0 3.5e-05 24.1 0.0 6.4 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KUM57891.1 - 1.7e-09 37.8 0.0 0.0034 17.6 0.0 4.3 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KUM57891.1 - 9.6e-06 25.6 0.0 1.1 9.3 0.0 4.2 5 0 0 5 5 5 2 BRCA1 C Terminus (BRCT) domain Nucleo_P87 PF07267.11 KUM57891.1 - 0.14 11.0 6.4 0.22 10.3 6.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HSP70 PF00012.20 KUM57892.1 - 5e-09 34.9 0.1 1.9e-07 29.7 0.0 2.5 3 0 0 3 3 3 2 Hsp70 protein APG6_N PF17675.1 KUM57893.1 - 0.00063 20.3 7.1 0.13 12.8 3.4 2.5 2 0 0 2 2 2 2 Apg6 coiled-coil region Coagulase PF08764.10 KUM57893.1 - 0.042 14.0 0.6 0.042 14.0 0.6 1.5 2 0 0 2 2 2 0 Staphylococcus aureus coagulase Sec8_exocyst PF04048.14 KUM57893.1 - 0.049 13.5 3.4 5.3 6.9 1.1 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF745 PF05335.13 KUM57893.1 - 0.14 11.8 1.4 0.27 10.9 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) AAA_23 PF13476.6 KUM57893.1 - 0.32 11.5 5.7 0.3 11.6 4.0 1.7 2 0 0 2 2 2 0 AAA domain CN_hydrolase PF00795.22 KUM57895.1 - 1e-54 185.6 0.0 1.2e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RNB PF00773.19 KUM57896.1 - 1.8e-99 333.2 0.1 4e-99 332.0 0.0 1.6 2 0 0 2 2 2 1 RNB domain Rrp44_S1 PF17215.3 KUM57896.1 - 1.2e-29 102.1 0.8 1.2e-29 102.1 0.8 2.0 2 0 0 2 2 2 1 S1 domain Rrp44_CSD1 PF17216.3 KUM57896.1 - 1.7e-29 102.4 0.1 5.8e-29 100.7 0.1 1.9 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 KUM57896.1 - 9.2e-21 73.7 0.0 2.2e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KUM57896.1 - 3.7e-08 33.7 0.1 2.5e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 PIN domain CSD2 PF17876.1 KUM57896.1 - 5.4e-08 32.9 0.0 1.3e-05 25.3 0.0 3.0 3 0 0 3 3 3 1 Cold shock domain Dna2 PF08696.11 KUM57897.1 - 1.6e-66 224.0 0.1 2.8e-66 223.2 0.1 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KUM57897.1 - 6.3e-52 176.1 0.0 9.5e-52 175.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KUM57897.1 - 7.5e-33 114.4 0.6 6.6e-16 58.9 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 KUM57897.1 - 4.1e-15 56.0 0.0 7.7e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KUM57897.1 - 2.1e-12 47.6 0.1 4.1e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 KUM57897.1 - 4.4e-08 33.4 0.7 8.8e-08 32.4 0.2 1.7 2 0 0 2 2 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 KUM57897.1 - 6.8e-07 29.5 0.1 1.9e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 KUM57897.1 - 1.6e-05 24.8 0.4 0.43 10.3 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KUM57897.1 - 0.00015 21.4 0.1 0.0003 20.4 0.1 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KUM57897.1 - 0.00018 21.4 0.0 0.00036 20.4 0.0 1.5 1 0 0 1 1 1 1 Helicase SRP54 PF00448.22 KUM57897.1 - 0.0012 18.6 0.1 0.0023 17.6 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KUM57897.1 - 0.004 17.6 0.0 0.01 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PIF1 PF05970.14 KUM57897.1 - 0.0041 16.3 0.1 0.013 14.7 0.1 1.8 1 1 0 1 1 1 1 PIF1-like helicase CbiA PF01656.23 KUM57897.1 - 0.0087 16.1 0.0 0.026 14.6 0.0 1.8 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 KUM57897.1 - 0.021 14.1 0.1 0.14 11.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KUM57897.1 - 0.025 14.1 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF87 PF01935.17 KUM57897.1 - 0.039 14.1 0.2 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain ResIII PF04851.15 KUM57897.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KUM57897.1 - 0.049 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 KUM57897.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 KUM57897.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KUM57897.1 - 0.13 11.3 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 KUM57897.1 - 0.15 12.5 0.1 6.7 7.2 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.6 KUM57897.1 - 0.16 12.5 0.0 0.55 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KUM57897.1 - 0.16 12.4 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KUM57897.1 - 0.17 11.9 0.0 0.53 10.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KUM57897.1 - 0.18 11.9 0.3 0.98 9.6 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 KUM57897.1 - 0.18 12.0 0.7 1.6 9.0 0.1 2.7 2 1 0 2 2 2 0 AAA domain ESSS PF10183.9 KUM57898.1 - 3.1e-18 65.9 0.0 3.6e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Methyltransf_4 PF02390.17 KUM57899.1 - 1.7e-44 151.3 0.6 4.5e-31 107.6 0.4 3.1 2 1 0 2 2 2 2 Putative methyltransferase Methyltransf_12 PF08242.12 KUM57899.1 - 0.00081 20.1 0.0 0.0022 18.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM57899.1 - 0.0014 19.3 0.0 0.0068 17.1 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 KUM57899.1 - 0.0054 16.3 0.0 0.069 12.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KUM57899.1 - 0.0058 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM57899.1 - 0.031 14.1 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF913 PF06025.12 KUM57899.1 - 0.057 12.4 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FmrO PF07091.11 KUM57899.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_11 PF08241.12 KUM57899.1 - 0.19 12.4 0.0 7.3 7.3 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain ESCRT-II PF05871.12 KUM57900.1 - 3.3e-52 176.5 0.0 4.1e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit MFS_1 PF07690.16 KUM57901.1 - 6.2e-24 84.6 44.9 1.7e-23 83.1 44.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily LIM PF00412.22 KUM57902.1 - 5.4e-26 90.6 27.3 2.4e-10 40.5 4.6 3.8 3 1 0 3 3 3 3 LIM domain Zn_ribbon_recom PF13408.6 KUM57902.1 - 0.086 13.4 1.4 0.23 12.0 0.1 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain MFS_1 PF07690.16 KUM57903.1 - 3.7e-35 121.5 67.2 9.9e-33 113.5 64.0 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DcpS PF05652.12 KUM57904.1 - 2e-33 115.3 0.0 3.2e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KUM57904.1 - 4.8e-29 101.1 0.0 8.1e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Cupin_5 PF06172.11 KUM57905.1 - 1.2e-40 139.0 0.0 1.4e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) RNase_T PF00929.24 KUM57907.1 - 1.4e-19 71.3 0.0 3.6e-19 69.9 0.0 1.7 1 1 0 1 1 1 1 Exonuclease Nop53 PF07767.11 KUM57908.1 - 1.8e-103 347.0 26.1 2.3e-103 346.7 26.1 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Peptidase_C37 PF05416.12 KUM57908.1 - 2.2 6.7 7.7 3.4 6.1 7.7 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase RNase_H2_suC PF08615.11 KUM57909.1 - 2.7e-30 105.4 0.0 3.4e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Peptidase_C12 PF01088.21 KUM57910.1 - 2.5e-52 177.7 0.0 2.9e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 EpuA PF11772.8 KUM57911.1 - 3.7 7.3 8.1 0.12 12.1 0.4 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Cu-oxidase_2 PF07731.14 KUM57912.1 - 4.9e-11 42.5 0.1 0.0016 18.2 0.2 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KUM57912.1 - 6.6e-11 42.3 0.0 4.4e-08 33.2 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KUM57912.1 - 0.0063 16.6 0.0 4.3 7.5 0.0 2.4 2 0 0 2 2 2 2 Cupredoxin-like domain Sugar_tr PF00083.24 KUM57913.1 - 4.2e-67 226.9 30.9 7.7e-66 222.8 30.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM57913.1 - 5.1e-16 58.5 41.5 5e-13 48.7 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KUM57913.1 - 0.0018 17.2 4.5 0.0018 17.2 4.5 2.4 2 0 0 2 2 2 2 MFS_1 like family Phage_holin_2_4 PF16082.5 KUM57913.1 - 0.022 14.5 0.7 0.087 12.6 0.7 2.1 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Indigoidine_A PF04227.12 KUM57915.1 - 4.1e-116 387.4 0.1 6.2e-116 386.8 0.1 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KUM57915.1 - 1.1e-15 57.7 0.6 4.7e-11 42.5 0.0 2.5 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Ribophorin_I PF04597.14 KUM57916.1 - 2.5e-148 494.9 0.1 3e-148 494.7 0.1 1.1 1 0 0 1 1 1 1 Ribophorin I Myb_Cef PF11831.8 KUM57917.1 - 5e-59 199.8 1.7 5e-59 199.8 1.7 3.5 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KUM57917.1 - 4.3e-22 78.0 4.4 6.5e-11 42.2 0.6 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KUM57917.1 - 1e-20 73.7 3.5 1.2e-13 51.1 0.7 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KUM57917.1 - 0.018 15.1 0.2 0.27 11.4 0.0 2.9 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain HTH_AsnC-type PF13404.6 KUM57917.1 - 0.051 13.4 1.9 0.79 9.6 0.0 2.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Fungal_trans_2 PF11951.8 KUM57918.1 - 8.6e-15 54.4 6.1 1.9e-14 53.3 6.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KUM57918.1 - 0.019 14.0 0.9 0.024 13.7 0.1 1.5 2 0 0 2 2 2 0 Fungal specific transcription factor domain MIT PF04212.18 KUM57918.1 - 0.68 10.0 0.0 0.68 10.0 0.0 2.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain HrpB1_HrpK PF09613.10 KUM57918.1 - 0.88 9.2 3.4 0.4 10.3 0.5 1.8 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Zn_clus PF00172.18 KUM57919.1 - 2.4e-09 37.1 10.3 6.4e-09 35.8 10.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 KUM57920.1 - 2.7e-49 168.1 49.5 3.4e-49 167.8 49.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM57920.1 - 5.9e-20 71.3 40.1 8.1e-20 70.9 40.1 1.1 1 0 0 1 1 1 1 Amino acid permease 2OG-FeII_Oxy PF03171.20 KUM57921.1 - 1.8e-15 57.3 0.0 2.2e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 KUM57922.1 - 5.3e-08 32.2 1.2 9.5e-08 31.4 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rieske PF00355.26 KUM57923.1 - 1.4e-15 57.0 0.0 2.5e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 KUM57923.1 - 4.8e-12 46.3 8.5 1.5e-07 31.6 0.2 2.7 2 1 1 3 3 3 2 Ring hydroxylating alpha subunit (catalytic domain) Peptidase_M3 PF01432.20 KUM57924.1 - 2.2e-08 33.8 0.1 1e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M3 DUF3581 PF12119.8 KUM57924.1 - 0.047 13.1 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3581) Fungal_trans PF04082.18 KUM57925.1 - 3e-11 42.9 0.1 4.5e-11 42.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phosphoesterase PF04185.14 KUM57926.1 - 9e-80 268.5 1.6 1.1e-79 268.2 1.6 1.1 1 0 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.23 KUM57926.1 - 0.01 15.3 0.2 3.3 7.0 0.0 2.9 3 0 0 3 3 3 0 Sulfatase FMO-like PF00743.19 KUM57928.1 - 2.1e-06 26.5 0.1 0.00044 18.8 0.0 2.9 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KUM57928.1 - 0.00012 21.3 0.0 0.0026 16.9 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KUM57928.1 - 0.00099 18.4 0.0 0.073 12.3 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM57928.1 - 0.0015 17.9 0.0 0.054 12.7 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM57928.1 - 0.0089 16.2 0.1 3.3 8.0 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KUM57928.1 - 0.27 9.9 0.3 1.4 7.6 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Ank_2 PF12796.7 KUM57929.1 - 2.3e-26 92.2 1.5 2e-12 47.5 0.1 4.2 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 KUM57929.1 - 6e-19 67.6 10.5 0.0036 17.7 0.2 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KUM57929.1 - 2.8e-18 64.1 5.7 0.026 15.0 0.1 7.3 7 0 0 7 7 6 4 Ankyrin repeat Ank_4 PF13637.6 KUM57929.1 - 4.6e-18 65.3 2.7 0.00015 22.2 0.1 5.5 4 2 2 6 6 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM57929.1 - 6.4e-14 51.8 1.9 0.0056 17.0 0.1 5.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) NACHT PF05729.12 KUM57929.1 - 3.5e-09 36.8 0.4 1e-08 35.2 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KUM57929.1 - 0.0024 18.2 0.0 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KUM57929.1 - 0.0041 17.5 0.0 0.013 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KUM57929.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF1678 PF07913.11 KUM57929.1 - 0.036 13.8 0.0 5.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1678) AAA_14 PF13173.6 KUM57929.1 - 0.07 13.2 0.0 1.6 8.8 0.0 2.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KUM57929.1 - 0.075 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 KUM57929.1 - 0.091 11.9 0.0 0.23 10.6 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KUM57929.1 - 0.099 13.2 0.0 0.98 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain zf_C2H2_13 PF18508.1 KUM57929.1 - 0.17 11.5 0.4 0.51 10.0 0.4 1.8 1 0 0 1 1 1 0 Zinc finger domain Zn_clus PF00172.18 KUM57930.1 - 2.2e-09 37.2 9.4 2.9e-09 36.9 9.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5488 PF17590.2 KUM57930.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5488) Transketolase_N PF00456.21 KUM57931.1 - 1.8e-126 421.6 0.0 2.6e-126 421.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KUM57931.1 - 8e-43 146.2 0.1 1.3e-42 145.5 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KUM57931.1 - 1.1e-06 28.5 0.0 2.9e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KUM57931.1 - 5.5e-06 25.8 0.0 2.3e-05 23.8 0.0 1.8 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KUM57931.1 - 0.00022 20.3 0.1 0.00069 18.7 0.1 1.8 3 0 0 3 3 3 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KUM57931.1 - 0.00023 21.0 0.1 0.0014 18.5 0.3 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ADH_N PF08240.12 KUM57932.1 - 5.5e-30 103.5 1.6 1.6e-29 102.0 0.9 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM57932.1 - 3.4e-14 53.0 0.0 5.6e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KUM57932.1 - 1.8e-06 27.6 1.5 4.1e-05 23.2 1.5 2.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KUM57932.1 - 0.016 14.5 0.9 0.12 11.7 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KUM57932.1 - 0.1 11.8 0.5 0.84 8.8 0.3 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_syntA PF00290.20 KUM57934.1 - 1.4e-67 227.3 0.0 2e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KUM57934.1 - 9.9e-46 156.5 0.7 1.8e-45 155.6 0.7 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ste5 PF11610.8 KUM57935.1 - 0.048 13.5 1.0 0.085 12.7 1.0 1.5 1 0 0 1 1 1 0 Scaffold protein Ste5, Fus3-binding region MFS_1 PF07690.16 KUM57936.1 - 5.8e-23 81.4 32.0 5.8e-23 81.4 32.0 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM57936.1 - 6.9e-07 28.5 9.3 6.9e-07 28.5 9.3 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter Glyco_hydro_31 PF01055.26 KUM57938.1 - 2e-114 383.2 0.7 2.5e-114 382.9 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KUM57938.1 - 5.3e-19 68.3 0.0 3.1e-18 65.9 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like Glyoxalase_5 PF14696.6 KUM57938.1 - 0.014 15.6 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Fungal_trans PF04082.18 KUM57939.1 - 1.1e-18 67.2 0.0 2.2e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM57939.1 - 2.3e-07 30.8 12.5 3.9e-07 30.1 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BLI1 PF17324.2 KUM57939.1 - 0.19 12.4 0.3 19 5.9 0.1 2.7 2 0 0 2 2 2 0 BLOC-1 interactor 1 IML1 PF12257.8 KUM57940.1 - 1.5e-112 375.4 0.0 2.1e-112 374.9 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KUM57940.1 - 2.8e-28 97.8 0.6 5.3e-28 96.9 0.6 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MFS_1 PF07690.16 KUM57941.1 - 1.4e-41 142.6 32.2 1.4e-41 142.6 32.2 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM57941.1 - 8e-14 51.3 10.9 8e-14 51.3 10.9 3.3 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 KUM57941.1 - 0.005 15.3 5.1 0.0088 14.5 5.1 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 KUM57941.1 - 0.056 11.7 8.0 0.0064 14.8 2.9 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Gly-zipper_Omp PF13488.6 KUM57941.1 - 4 7.5 6.1 36 4.4 0.1 2.9 2 0 0 2 2 2 0 Glycine zipper DUF1269 PF06897.12 KUM57941.1 - 6.3 7.1 7.8 1.2 9.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) Fungal_trans PF04082.18 KUM57942.1 - 3.2e-07 29.7 2.5 8.8e-07 28.2 2.5 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM57942.1 - 6.3e-07 29.4 11.2 1.2e-06 28.6 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_UL32 PF06070.11 KUM57942.1 - 0.051 11.3 5.1 0.074 10.8 5.1 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 FNIP_N PF14636.6 KUM57943.1 - 5.9e-29 102.0 0.0 5.9e-29 102.0 0.0 4.0 2 1 0 2 2 2 1 Folliculin-interacting protein N-terminus LIM_bind PF01803.16 KUM57945.1 - 3.7e-70 236.2 0.1 3.7e-70 236.2 0.1 4.4 2 1 1 3 3 3 1 LIM-domain binding protein RIBIOP_C PF04950.12 KUM57946.1 - 1.8e-104 349.3 0.0 3.1e-104 348.5 0.0 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KUM57946.1 - 2.4e-21 75.6 0.0 6.1e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain SNAP PF14938.6 KUM57947.1 - 1.1e-116 389.2 11.4 1.3e-116 389.0 11.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KUM57947.1 - 4e-05 23.8 14.1 0.02 15.2 0.9 4.5 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KUM57947.1 - 0.0037 17.3 14.2 0.034 14.3 0.4 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KUM57947.1 - 0.0042 17.0 9.2 0.55 10.4 0.4 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KUM57947.1 - 0.0057 17.2 12.3 0.75 10.6 0.8 5.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KUM57947.1 - 0.0058 16.4 19.7 0.23 11.3 0.4 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat DUF2811 PF10929.8 KUM57947.1 - 0.012 15.9 0.3 0.033 14.4 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) PhoU PF01895.19 KUM57947.1 - 0.015 15.7 1.8 4.8 7.7 0.3 2.9 1 1 1 2 2 2 0 PhoU domain Hep_59 PF07052.11 KUM57947.1 - 0.056 14.2 0.7 0.15 12.8 0.7 1.7 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 NSF PF02071.20 KUM57947.1 - 0.13 13.1 17.6 1.1 10.3 0.3 7.1 7 1 1 8 8 7 0 Aromatic-di-Alanine (AdAR) repeat MIT PF04212.18 KUM57947.1 - 0.56 10.3 16.7 3 8.0 0.6 4.2 2 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 KUM57947.1 - 1 9.7 23.5 1.1 9.5 0.7 7.1 4 3 3 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 KUM57947.1 - 1.1 10.3 11.9 4.6 8.3 1.5 4.7 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KUM57947.1 - 1.7 8.6 6.6 7.7 6.5 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat cobW PF02492.19 KUM57948.1 - 9.8e-33 113.2 0.0 1.2e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KUM57948.1 - 2e-05 23.7 1.7 0.00024 20.2 1.7 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KUM57948.1 - 0.0061 16.6 0.0 0.015 15.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KUM57948.1 - 0.011 16.1 0.0 0.014 15.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KUM57948.1 - 0.02 15.5 0.0 0.029 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KUM57948.1 - 0.023 14.7 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KUM57948.1 - 0.024 13.9 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KUM57948.1 - 0.039 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PRK PF00485.18 KUM57948.1 - 0.052 13.3 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_21 PF13304.6 KUM57948.1 - 0.065 13.0 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KUM57948.1 - 0.15 12.5 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KUM57948.1 - 0.17 12.4 0.0 0.24 11.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 KUM57948.1 - 0.19 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin BING4CT PF08149.11 KUM57949.1 - 2.7e-38 129.6 0.0 6.5e-35 118.8 0.0 2.7 2 0 0 2 2 2 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KUM57949.1 - 6.8e-09 35.9 0.2 0.42 11.0 0.0 5.8 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KUM57949.1 - 0.0013 19.5 1.0 0.31 12.0 0.0 4.1 3 2 1 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KUM57949.1 - 0.012 14.7 0.0 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 Coatomer WD associated region HNF_C PF09354.10 KUM57949.1 - 0.046 14.8 0.0 0.11 13.6 0.0 1.6 1 0 0 1 1 1 0 HNF3 C-terminal domain TTRAP PF14203.6 KUM57949.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein DUF726 PF05277.12 KUM57950.1 - 3.8e-122 407.5 1.0 4.9e-122 407.1 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 KUM57950.1 - 8.4e-05 22.8 0.0 0.00022 21.4 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain DUF900 PF05990.12 KUM57950.1 - 0.072 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Cutinase PF01083.22 KUM57950.1 - 0.091 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase Hydrolase_4 PF12146.8 KUM57950.1 - 0.11 11.8 0.1 0.3 10.3 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Glu-tRNAGln PF02686.15 KUM57951.1 - 2.4e-11 43.7 0.2 2.3e-10 40.6 0.2 2.1 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit TPR_12 PF13424.6 KUM57952.1 - 6.3e-62 205.8 44.1 1e-18 67.4 3.8 5.4 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KUM57952.1 - 3.7e-54 179.2 25.3 7.4e-11 41.6 0.3 7.5 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 KUM57952.1 - 7.6e-30 101.5 23.8 7.4e-06 25.6 0.3 7.0 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 KUM57952.1 - 2.5e-26 89.7 28.5 0.00013 21.7 0.4 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 KUM57952.1 - 5.7e-25 85.4 18.4 0.00043 20.3 0.1 7.0 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KUM57952.1 - 8.3e-24 81.7 23.7 0.00047 20.1 0.3 6.9 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_MalT PF17874.1 KUM57952.1 - 9.1e-17 61.4 10.5 5.8e-09 35.8 3.8 2.6 1 1 1 2 2 2 2 MalT-like TPR region TPR_4 PF07721.14 KUM57952.1 - 1.5e-13 49.9 11.3 0.077 13.7 0.1 6.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KUM57952.1 - 1.5e-13 51.1 28.3 0.00074 20.1 5.0 6.2 5 2 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KUM57952.1 - 1.8e-12 47.0 20.0 0.14 13.0 0.1 7.5 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KUM57952.1 - 8.1e-11 41.5 12.5 0.89 10.1 0.1 7.8 7 1 0 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KUM57952.1 - 8e-10 39.1 16.9 0.0015 19.0 2.6 4.9 3 1 1 5 5 4 3 Tetratricopeptide repeat NB-ARC PF00931.22 KUM57952.1 - 3.4e-08 33.0 0.0 0.0078 15.4 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_16 PF13191.6 KUM57952.1 - 2.7e-06 27.9 0.0 6.9e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PNP_UDP_1 PF01048.20 KUM57952.1 - 8.5e-06 25.2 0.5 4.2e-05 22.9 0.5 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily DUF2225 PF09986.9 KUM57952.1 - 2.7e-05 24.0 5.3 0.02 14.6 1.0 3.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.6 KUM57952.1 - 0.00074 20.0 25.9 4.1 8.3 0.4 7.0 6 0 0 6 6 6 2 Tetratricopeptide repeat RPN7 PF10602.9 KUM57952.1 - 0.0016 18.2 5.2 4.7 6.9 0.1 4.7 1 1 4 5 5 5 1 26S proteasome subunit RPN7 PPR PF01535.20 KUM57952.1 - 0.0031 17.6 1.5 9.7 6.7 0.0 5.7 7 0 0 7 7 5 0 PPR repeat ANAPC3 PF12895.7 KUM57952.1 - 0.0034 17.6 4.2 0.82 9.9 0.2 4.3 2 1 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 RPN6_N PF18055.1 KUM57952.1 - 0.0047 17.3 2.7 4.4 7.7 0.1 3.7 1 1 3 4 4 4 1 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_11 PF13414.6 KUM57952.1 - 0.018 14.7 35.1 1.1 9.0 1.7 6.5 6 0 0 6 6 6 0 TPR repeat ATPase_2 PF01637.18 KUM57952.1 - 0.028 14.3 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_21 PF09976.9 KUM57952.1 - 0.047 13.4 18.0 4.4 7.0 0.3 5.4 1 1 4 5 5 5 0 Tetratricopeptide repeat-like domain Phage_DsbA PF11126.8 KUM57952.1 - 0.2 11.9 0.4 13 6.1 0.0 3.1 3 0 0 3 3 2 0 Transcriptional regulator DsbA DUF3726 PF12525.8 KUM57952.1 - 0.57 10.3 9.9 59 3.9 0.1 5.2 6 0 0 6 6 4 0 Protein of unknown function (DUF3726) DUF1897 PF09005.10 KUM57952.1 - 6.2 6.4 19.6 3.6 7.1 0.2 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1897) RPN6_C_helix PF18503.1 KUM57952.1 - 7.9 6.3 6.3 73 3.2 0.1 4.5 4 0 0 4 4 3 0 26S proteasome subunit RPN6 C-terminal helix domain Peptidase_M20 PF01546.28 KUM57953.1 - 3.2e-24 85.8 0.1 4.6e-24 85.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KUM57953.1 - 1e-11 44.7 0.0 2.1e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF3995 PF13160.6 KUM57953.1 - 0.58 10.5 2.5 0.59 10.5 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3995) ADH_zinc_N_2 PF13602.6 KUM57954.1 - 6.7e-28 98.4 0.2 1.2e-27 97.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KUM57954.1 - 1.7e-14 53.9 0.1 2.7e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM57954.1 - 0.0087 15.9 0.1 0.036 13.9 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Fe_hyd_lg_C PF02906.14 KUM57954.1 - 0.036 13.7 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Methyltransf_2 PF00891.18 KUM57958.1 - 4.4e-21 75.1 0.0 1.5e-20 73.4 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 KUM57958.1 - 0.00058 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.6 KUM57958.1 - 0.014 15.2 0.0 0.039 13.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_19 PF04672.12 KUM57958.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase Dimerisation PF08100.11 KUM57958.1 - 0.17 11.9 0.2 0.87 9.7 0.1 2.3 2 1 0 2 2 2 0 Dimerisation domain DIOX_N PF14226.6 KUM57959.1 - 7.4e-25 88.0 0.0 1.4e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KUM57959.1 - 3.3e-14 53.2 0.0 7.5e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1932 PF09130.11 KUM57959.1 - 0.066 13.2 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1932) DIOX_N PF14226.6 KUM57960.1 - 8e-08 33.0 0.1 1.3e-07 32.3 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KUM57960.1 - 6e-07 29.9 0.0 1.2e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 KUM57961.1 - 3.3e-66 223.6 0.0 4.4e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KUM57961.1 - 8.6e-19 68.6 0.0 2.9e-18 66.9 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 KUM57961.1 - 1.8e-08 34.6 0.0 4e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM57961.1 - 0.0031 18.4 0.4 0.0082 17.1 0.4 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_2 PF00891.18 KUM57962.1 - 1.9e-20 73.1 0.0 2.9e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KUM57962.1 - 0.00025 21.0 0.1 0.00065 19.7 0.1 1.8 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 KUM57962.1 - 0.0066 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain p450 PF00067.22 KUM57963.1 - 4.6e-28 98.2 0.0 7.1e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Dyp_perox PF04261.12 KUM57964.1 - 3.6e-09 36.1 0.0 9.7e-07 28.1 0.0 3.0 3 0 0 3 3 3 3 Dyp-type peroxidase family FAD_binding_3 PF01494.19 KUM57965.1 - 4.8e-14 52.4 0.0 1.2e-06 28.1 0.3 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KUM57965.1 - 1.2e-06 28.4 0.3 0.00018 21.2 0.0 2.9 1 1 2 3 3 3 1 FAD dependent oxidoreductase SE PF08491.10 KUM57965.1 - 0.00044 19.4 0.0 0.5 9.4 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase GIDA PF01134.22 KUM57965.1 - 0.057 12.5 0.0 0.087 11.9 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF3106 PF11304.8 KUM57965.1 - 1.1 9.8 4.5 1.1 9.8 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Haem_oxygenas_2 PF14518.6 KUM57966.1 - 2e-32 112.4 0.1 4.5e-32 111.2 0.1 1.6 2 0 0 2 2 2 1 Iron-containing redox enzyme COesterase PF00135.28 KUM57967.1 - 6.2e-44 150.7 0.0 1.3e-43 149.7 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KUM57967.1 - 0.00014 21.8 0.0 0.0011 18.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold MFS_1 PF07690.16 KUM57968.1 - 1e-40 139.8 26.2 1.5e-40 139.3 26.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM57968.1 - 4.9e-10 38.9 7.7 4.9e-10 38.9 7.7 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KUM57968.1 - 1.1e-07 30.6 2.6 1.1e-07 30.6 2.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4449 PF14613.6 KUM57969.1 - 6.8e-61 205.1 0.2 6.8e-61 205.1 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Evr1_Alr PF04777.13 KUM57969.1 - 0.015 15.7 0.5 0.057 13.9 0.1 2.3 2 0 0 2 2 2 0 Erv1 / Alr family AIRC PF00731.20 KUM57970.1 - 2.8e-58 195.7 2.1 5.1e-58 194.9 1.5 1.7 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 KUM57970.1 - 3.3e-51 173.3 0.0 6.7e-51 172.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KUM57970.1 - 4e-18 64.8 0.1 1.1e-17 63.4 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KUM57970.1 - 2.4e-06 27.2 0.0 5.7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 KUM57970.1 - 1.1e-05 25.1 0.0 7.1e-05 22.4 0.0 2.2 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus AlaDh_PNT_C PF01262.21 KUM57970.1 - 0.00077 18.8 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_M15_3 PF08291.11 KUM57970.1 - 0.0039 17.2 0.2 0.8 9.8 0.0 3.5 3 1 0 3 3 3 1 Peptidase M15 ATP-grasp_5 PF13549.6 KUM57970.1 - 0.0049 16.4 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PrpR_N PF06506.11 KUM57970.1 - 0.006 16.2 0.4 0.04 13.5 0.1 2.5 3 0 0 3 3 3 1 Propionate catabolism activator XdhC_C PF13478.6 KUM57970.1 - 0.022 15.3 0.0 0.34 11.4 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 KUM57970.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PPP4R2 PF09184.11 KUM57971.1 - 1.8e-09 37.6 0.0 4.1e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 PPP4R2 HSF_DNA-bind PF00447.17 KUM57972.1 - 1.2e-31 109.1 1.7 2.9e-31 107.9 1.7 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KUM57972.1 - 2.1e-22 79.4 0.0 5e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain FTO_CTD PF12934.7 KUM57972.1 - 0.087 12.6 0.9 0.18 11.6 0.1 1.8 2 0 0 2 2 2 0 FTO C-terminal domain DivIC PF04977.15 KUM57972.1 - 0.33 10.8 1.5 0.67 9.8 1.5 1.4 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 KUM57972.1 - 0.52 11.0 8.7 0.26 11.9 5.6 2.2 2 0 0 2 2 2 0 SlyX Redoxin PF08534.10 KUM57973.1 - 1.9e-26 92.5 0.0 2.5e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KUM57973.1 - 3.9e-07 30.0 0.0 5.3e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family BolA PF01722.18 KUM57974.1 - 7.2e-19 67.8 0.1 2.7e-18 66.0 0.0 1.9 2 1 0 2 2 2 1 BolA-like protein PSD5 PF07637.11 KUM57974.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) NIF3 PF01784.18 KUM57975.1 - 1.6e-58 198.2 0.0 2.3e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) ENTH PF01417.20 KUM57976.1 - 1.2e-46 157.8 0.0 2.2e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 KUM57976.1 - 0.00095 19.5 36.2 0.00095 19.5 36.2 5.9 1 1 3 4 4 4 1 Domain of unknown function (DUF1720) UIM PF02809.20 KUM57976.1 - 0.0016 18.2 4.0 0.013 15.3 1.2 2.6 2 0 0 2 2 2 1 Ubiquitin interaction motif ANTH PF07651.16 KUM57976.1 - 0.0019 17.3 0.0 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.6 KUM57976.1 - 0.076 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Ank_4 PF13637.6 KUM57977.1 - 3e-36 123.3 7.0 2.5e-09 37.5 0.0 4.4 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KUM57977.1 - 1.7e-32 111.8 1.1 1.1e-10 41.9 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KUM57977.1 - 1e-27 93.1 2.4 0.00016 21.9 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KUM57977.1 - 7e-25 86.3 8.7 2.6e-05 24.5 0.0 5.8 5 1 1 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KUM57977.1 - 2.1e-23 82.1 0.7 1.1e-06 28.8 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Sigma_M_inh PF17453.2 KUM57977.1 - 0.023 15.1 0.0 0.057 13.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-M inhibitor DUF3447 PF11929.8 KUM57977.1 - 0.11 12.5 0.0 0.87 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) Cyanate_lyase PF02560.14 KUM57981.1 - 1.4e-32 111.3 0.1 2.4e-32 110.6 0.0 1.4 2 0 0 2 2 2 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 KUM57981.1 - 0.061 13.7 0.0 0.094 13.1 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Carb_kinase PF01256.17 KUM57982.1 - 0.052 13.0 1.1 0.093 12.2 0.8 1.5 1 1 1 2 2 2 0 Carbohydrate kinase zf-C2H2_4 PF13894.6 KUM57983.1 - 4.5e-06 27.1 24.1 0.13 13.1 0.1 6.6 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KUM57983.1 - 1.6e-05 25.0 19.7 0.15 12.6 0.0 5.8 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KUM57983.1 - 0.0012 18.8 9.7 1.2 9.2 1.4 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger DUF4187 PF13821.6 KUM57983.1 - 0.074 12.8 3.1 2.9 7.7 0.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) zf-C2H2_8 PF15909.5 KUM57983.1 - 0.94 9.8 15.0 5.8 7.3 7.7 3.5 2 1 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KUM57983.1 - 9.4 6.6 26.2 0.72 10.2 0.3 4.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DNA_pol_B PF00136.21 KUM57985.1 - 2.4e-149 498.0 1.8 3.5e-149 497.4 1.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KUM57985.1 - 2.6e-79 266.8 0.0 4.5e-79 266.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KUM57985.1 - 3.1e-18 66.0 7.3 6.5e-18 65.0 7.3 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KUM57985.1 - 0.0032 16.4 0.2 0.034 13.0 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 KUM57985.1 - 0.011 15.8 0.6 0.083 12.9 0.6 2.4 1 1 0 1 1 1 0 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 KUM57985.1 - 0.065 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB ETC_C1_NDUFA5 PF04716.14 KUM57985.1 - 0.091 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 ETC complex I subunit conserved region DUF2508 PF10704.9 KUM57985.1 - 2.6 8.3 0.0 2.6 8.3 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2508) Pkinase PF00069.25 KUM57986.1 - 1.2e-33 116.7 0.0 1.1e-18 67.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KUM57986.1 - 1.1e-16 60.9 0.0 5.2e-07 29.2 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.14 KUM57986.1 - 0.042 13.2 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KUM57986.1 - 0.058 12.2 1.7 0.12 11.2 0.0 2.2 3 0 0 3 3 3 0 Fungal protein kinase FTA2 PF13095.6 KUM57986.1 - 0.077 12.6 0.0 6.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Acyl-CoA_dh_1 PF00441.24 KUM57987.1 - 1.6e-30 106.3 0.1 2.4e-30 105.7 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KUM57987.1 - 3.4e-26 92.1 0.0 9.1e-26 90.7 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KUM57987.1 - 3.3e-23 81.7 0.0 5.6e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KUM57987.1 - 8e-05 22.9 0.1 0.00013 22.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Lipocalin_9 PF17186.4 KUM57988.1 - 0.0051 17.1 0.0 0.0097 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipocalin-like domain CrtC PF07143.11 KUM57988.1 - 0.065 13.9 0.0 0.15 12.7 0.0 1.7 2 0 0 2 2 2 0 CrtC N-terminal lipocalin domain DUF2157 PF09925.9 KUM57989.1 - 0.019 14.7 0.2 0.044 13.6 0.1 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF4013 PF13197.6 KUM57989.1 - 0.021 14.7 2.1 0.021 14.7 2.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) Glyco_hydro_125 PF06824.11 KUM57990.1 - 9.5e-180 597.9 0.1 1.1e-179 597.7 0.1 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) CDC27 PF09507.10 KUM57991.1 - 1.6e-76 258.4 30.1 2e-76 258.1 30.1 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 SAP PF02037.27 KUM57992.1 - 1.4e-05 24.7 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 SAP domain Snf7 PF03357.21 KUM57993.1 - 1.7e-16 60.3 13.2 2.5e-16 59.8 12.9 1.5 1 1 0 1 1 1 1 Snf7 TssO PF17561.2 KUM57993.1 - 0.018 15.2 1.1 0.043 13.9 1.1 1.6 1 0 0 1 1 1 0 Type VI secretion system, TssO MbeD_MobD PF04899.12 KUM57993.1 - 0.32 11.2 3.0 0.39 10.9 0.1 2.6 2 0 0 2 2 2 0 MbeD/MobD like HSBP1 PF06825.12 KUM57993.1 - 0.33 10.8 3.2 5.7 6.9 0.0 3.4 3 0 0 3 3 3 0 Heat shock factor binding protein 1 FAM76 PF16046.5 KUM57993.1 - 0.67 9.3 7.9 0.14 11.5 2.9 2.0 2 0 0 2 2 2 0 FAM76 protein DUF16 PF01519.16 KUM57993.1 - 6.2 7.4 7.1 4.5 7.8 4.1 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 Glyco_hydro_64 PF16483.5 KUM57994.1 - 2.5e-137 458.1 5.4 3e-137 457.8 5.4 1.1 1 0 0 1 1 1 1 Beta-1,3-glucanase Abhydrolase_6 PF12697.7 KUM57995.1 - 1e-13 52.4 1.1 1.2e-13 52.2 1.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family MBF1 PF08523.10 KUM57995.1 - 0.13 12.8 0.4 0.46 11.0 0.1 2.0 2 0 0 2 2 2 0 Multiprotein bridging factor 1 Methyltransf_2 PF00891.18 KUM57996.1 - 7.5e-20 71.1 0.0 1.3e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KUM57996.1 - 0.00074 19.5 0.3 0.0033 17.4 0.3 2.2 1 0 0 1 1 1 1 Dimerisation domain HTH_IclR PF09339.10 KUM57996.1 - 0.0037 17.0 0.4 0.016 15.0 0.1 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain Rrf2 PF02082.20 KUM57996.1 - 0.012 15.9 0.1 0.055 13.8 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator HTH_5 PF01022.20 KUM57996.1 - 0.03 14.2 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 KUM57996.1 - 0.039 13.8 0.1 0.098 12.6 0.1 1.6 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.6 KUM57996.1 - 0.053 13.5 0.0 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KUM57996.1 - 0.058 13.0 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 KUM57996.1 - 0.11 12.6 0.7 0.96 9.6 0.1 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 KUM57996.1 - 0.17 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Trypan_PARP PF05887.11 KUM57998.1 - 2.5 8.1 35.6 22 5.0 35.6 2.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Aldo_ket_red PF00248.21 KUM58000.1 - 2.5e-39 135.2 0.0 1.9e-32 112.6 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Seadorna_Vp10 PF07322.11 KUM58000.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus Vp10 Polysacc_synt_4 PF04669.13 KUM58001.1 - 8.5e-19 67.8 1.7 3.3e-17 62.7 1.7 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis ABC_membrane PF00664.23 KUM58002.1 - 7.4e-85 284.9 27.2 7e-43 147.2 8.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KUM58002.1 - 1.3e-60 203.9 0.0 8.3e-29 100.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KUM58002.1 - 1.7e-18 66.9 1.4 4e-08 33.0 0.1 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KUM58002.1 - 1.8e-12 47.7 1.2 0.13 12.0 0.0 4.6 5 0 0 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KUM58002.1 - 1.4e-08 34.3 0.7 0.0052 16.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KUM58002.1 - 4.9e-07 30.1 0.2 0.015 15.6 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.6 KUM58002.1 - 5.6e-06 26.1 0.1 0.34 10.5 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 KUM58002.1 - 6.6e-06 26.6 0.4 0.3 11.4 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KUM58002.1 - 2.6e-05 24.2 0.5 0.46 10.4 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_15 PF13175.6 KUM58002.1 - 2.7e-05 24.1 1.1 0.098 12.3 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 KUM58002.1 - 0.0003 21.0 0.0 0.34 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KUM58002.1 - 0.00048 20.3 0.3 1.1 9.3 0.0 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_18 PF13238.6 KUM58002.1 - 0.00053 20.5 0.2 0.4 11.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KUM58002.1 - 0.00095 19.2 0.1 2.6 8.0 0.1 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF3987 PF13148.6 KUM58002.1 - 0.0019 17.3 0.1 1.4 7.8 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) AAA PF00004.29 KUM58002.1 - 0.0032 17.9 0.0 0.16 12.4 0.0 3.4 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 KUM58002.1 - 0.0065 15.3 2.6 0.41 9.4 0.1 3.1 3 1 0 3 3 3 1 Predicted ATPase of the ABC class RNA_helicase PF00910.22 KUM58002.1 - 0.0066 16.8 0.1 1.7 9.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_23 PF13476.6 KUM58002.1 - 0.009 16.5 0.4 1.1 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KUM58002.1 - 0.011 15.9 1.3 2.8 8.0 0.1 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 KUM58002.1 - 0.016 15.4 0.1 11 6.3 0.0 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.20 KUM58002.1 - 0.029 14.3 0.1 8.6 6.2 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase NACHT PF05729.12 KUM58002.1 - 0.032 14.2 1.3 2.5 8.0 0.1 2.8 3 0 0 3 3 2 0 NACHT domain FtsK_SpoIIIE PF01580.18 KUM58002.1 - 0.053 12.9 0.0 9.7 5.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family CbiA PF01656.23 KUM58002.1 - 0.057 13.5 0.2 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_13 PF13166.6 KUM58002.1 - 0.08 11.6 0.1 6.5 5.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KUM58002.1 - 0.096 12.4 1.0 18 5.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.7 KUM58002.1 - 0.12 11.2 0.0 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain NB-ARC PF00931.22 KUM58002.1 - 0.13 11.5 0.8 6.3 5.9 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_30 PF13604.6 KUM58002.1 - 0.18 11.5 0.7 18 5.0 0.0 3.3 4 0 0 4 4 4 0 AAA domain G-alpha PF00503.20 KUM58002.1 - 0.19 10.9 0.5 6.2 5.9 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit ATPase PF06745.13 KUM58002.1 - 1.1 8.6 7.2 4.7 6.5 0.1 3.8 5 0 0 5 5 5 0 KaiC Rif1_N PF12231.8 KUM58003.1 - 1.7e-138 461.7 0.2 2.5e-138 461.2 0.2 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal PSY3 PF16836.5 KUM58003.1 - 0.029 13.9 0.2 46 3.4 0.0 3.3 3 0 0 3 3 3 0 Shu complex component Psy3, DNA-binding description Ric8 PF10165.9 KUM58004.1 - 1.1e-116 390.6 0.0 1.4e-116 390.3 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Cnd3 PF12719.7 KUM58004.1 - 0.016 14.5 0.0 0.041 13.1 0.0 1.7 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Ribosomal_L26 PF16906.5 KUM58005.1 - 5.7e-36 122.8 1.6 7e-36 122.6 1.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KUM58005.1 - 2.3e-05 24.2 0.3 5.8e-05 22.9 0.3 1.7 1 0 0 1 1 1 1 KOW motif Synaptobrevin PF00957.21 KUM58008.1 - 1.1e-31 108.4 0.0 1.5e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KUM58008.1 - 1.4e-26 92.3 0.1 2.6e-26 91.5 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain CorA PF01544.18 KUM58009.1 - 0.00029 20.3 11.6 0.0014 18.1 11.7 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein MCM_bind PF09739.9 KUM58009.1 - 0.093 11.2 0.2 0.84 8.0 0.2 1.9 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor BatD PF13584.6 KUM58009.1 - 0.13 11.1 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Oxygen tolerance HTH_16 PF12645.7 KUM58009.1 - 0.54 10.3 1.9 4 7.6 0.2 2.9 2 1 1 3 3 3 0 Helix-turn-helix domain MAS20 PF02064.15 KUM58011.1 - 4.6e-43 146.4 0.2 5.3e-43 146.2 0.2 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor Ntox1 PF15500.6 KUM58011.1 - 0.14 12.5 1.3 0.23 11.8 1.3 1.3 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 CPSase_L_D2 PF02786.17 KUM58012.1 - 5.1e-114 379.0 0.1 1.2e-83 279.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 KUM58012.1 - 3.1e-47 160.8 0.0 2.2e-46 158.0 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KUM58012.1 - 2.4e-46 156.7 0.0 5.8e-46 155.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 KUM58012.1 - 3.4e-46 156.9 0.0 7.7e-46 155.8 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KUM58012.1 - 2.3e-37 128.1 0.0 5e-37 127.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KUM58012.1 - 1.3e-29 103.3 0.0 3.3e-29 102.0 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KUM58012.1 - 4.7e-20 71.6 0.0 1.9e-19 69.6 0.0 2.2 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KUM58012.1 - 4.4e-17 62.3 0.4 3.4e-08 33.3 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KUM58012.1 - 1.3e-14 54.1 0.0 1.6e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KUM58012.1 - 2.5e-09 37.0 0.0 0.00025 20.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KUM58012.1 - 8.4e-06 25.7 0.1 0.00052 19.8 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 KUM58012.1 - 0.00013 22.0 0.5 0.43 10.6 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KUM58012.1 - 0.0024 17.7 0.7 0.65 9.8 0.0 4.3 5 0 0 5 5 5 1 DJ-1/PfpI family RimK PF08443.11 KUM58012.1 - 0.0027 17.3 0.0 1.8 8.1 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain AMP-binding PF00501.28 KUM58013.1 - 1e-76 258.2 0.0 1.3e-76 257.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.16 KUM58013.1 - 1.2e-26 93.5 17.9 2.2e-26 92.6 17.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily AMP-binding_C PF13193.6 KUM58013.1 - 2.3e-10 41.3 0.5 5.8e-10 40.0 0.5 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Exo84_C PF16528.5 KUM58015.1 - 9.4e-67 224.8 0.0 9.4e-67 224.8 0.0 1.8 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KUM58015.1 - 1.5e-18 66.7 1.4 3.3e-18 65.5 1.4 1.6 1 0 0 1 1 1 1 Vps51/Vps67 DUF2594 PF10769.9 KUM58015.1 - 0.092 12.8 0.3 0.23 11.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2594) HIP1_clath_bdg PF16515.5 KUM58015.1 - 1.9 9.1 6.0 0.71 10.5 2.7 1.9 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Sec63 PF02889.16 KUM58016.1 - 6.8e-132 438.3 0.0 2.9e-81 272.4 0.0 2.6 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KUM58016.1 - 3.4e-52 176.7 0.5 1.4e-26 93.3 0.7 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 KUM58016.1 - 3.9e-22 79.1 0.0 4.6e-11 43.0 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KUM58016.1 - 1.3e-17 64.2 0.1 6.5e-07 29.7 0.0 4.4 4 2 0 4 4 4 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KUM58016.1 - 3.6e-09 37.0 0.0 0.0006 20.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KUM58016.1 - 2.9e-07 30.4 0.2 0.006 16.3 0.3 2.4 2 0 0 2 2 2 2 AAA domain Helicase_PWI PF18149.1 KUM58016.1 - 2.3e-05 24.5 0.1 7.2e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain AAA_19 PF13245.6 KUM58016.1 - 3.8e-05 24.1 0.8 0.0072 16.7 0.9 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KUM58016.1 - 0.053 13.2 0.4 4.2 7.1 0.0 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein PhoH PF02562.16 KUM58016.1 - 0.073 12.5 0.0 8.4 5.8 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein TniB PF05621.11 KUM58016.1 - 0.13 11.6 0.3 16 4.8 0.0 3.3 4 0 0 4 4 4 0 Bacterial TniB protein Synaptobrevin PF00957.21 KUM58017.1 - 6.3e-15 54.7 0.7 1.1e-14 54.0 0.7 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KUM58017.1 - 4.1e-12 46.0 0.0 8.6e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain FAD_binding_3 PF01494.19 KUM58018.1 - 2.6e-12 46.7 0.0 5e-11 42.4 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KUM58018.1 - 0.00019 21.2 0.0 0.0005 19.8 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KUM58018.1 - 0.0016 18.4 0.0 0.029 14.4 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KUM58018.1 - 0.0024 17.2 0.0 0.0056 16.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM58018.1 - 0.005 17.0 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF3666 PF12408.8 KUM58018.1 - 0.47 9.7 1.3 0.55 9.5 0.0 1.8 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase YL1_C PF08265.11 KUM58019.1 - 7.3e-16 57.6 0.4 1.4e-15 56.7 0.4 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Profilin PF00235.19 KUM58020.1 - 6.3e-39 133.1 0.2 7.3e-39 132.9 0.2 1.0 1 0 0 1 1 1 1 Profilin AA_permease PF00324.21 KUM58022.1 - 1.9e-104 350.0 31.5 2.6e-104 349.5 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM58022.1 - 2e-27 96.1 35.1 2.6e-27 95.7 35.1 1.1 1 0 0 1 1 1 1 Amino acid permease TMEM40 PF15817.5 KUM58022.1 - 0.024 14.4 0.2 0.21 11.4 0.0 2.5 3 0 0 3 3 3 0 Transmembrane protein 40 family DUF4781 PF16013.5 KUM58022.1 - 0.039 12.8 0.4 0.071 11.9 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) HDOD PF08668.12 KUM58022.1 - 0.2 11.1 0.6 0.33 10.4 0.6 1.2 1 0 0 1 1 1 0 HDOD domain HPP PF04982.13 KUM58023.1 - 1.1e-43 148.3 10.0 2.7e-43 147.0 7.8 2.0 2 0 0 2 2 2 1 HPP family DUF4231 PF14015.6 KUM58023.1 - 0.25 11.8 0.1 0.25 11.8 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF3792 PF12670.7 KUM58023.1 - 7.7 6.7 9.6 1.2 9.4 5.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Got1 PF04178.12 KUM58025.1 - 5.6e-05 23.5 1.0 6.7e-05 23.3 1.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Fungal_trans PF04082.18 KUM58026.1 - 1.5e-09 37.3 0.0 2.6e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_2 PF07883.11 KUM58027.1 - 5.6e-10 38.8 0.0 7.8e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KUM58027.1 - 0.00033 20.3 0.0 0.00037 20.1 0.0 1.2 1 0 0 1 1 1 1 Cupin DUF4437 PF14499.6 KUM58027.1 - 0.026 13.7 0.0 0.032 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) DASH_Dad4 PF08650.10 KUM58028.1 - 2.9e-32 110.5 8.4 3.2e-32 110.3 8.4 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.17 KUM58028.1 - 0.055 13.6 0.3 0.062 13.5 0.3 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Biotin_carb_C PF02785.19 KUM58028.1 - 0.12 12.4 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain Actin PF00022.19 KUM58029.1 - 3.7e-53 180.6 0.0 3.8e-29 101.5 0.0 2.3 2 1 0 2 2 2 2 Actin Acetyltransf_3 PF13302.7 KUM58030.1 - 1.9e-28 99.8 0.0 2.4e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM58030.1 - 0.00099 19.3 0.0 0.006 16.8 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family V_ATPase_I PF01496.19 KUM58031.1 - 0 1078.2 0.0 0 1078.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CheZ PF04344.13 KUM58031.1 - 0.016 15.1 1.7 0.13 12.1 0.1 2.4 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ DUF1515 PF07439.11 KUM58031.1 - 0.032 14.2 0.1 0.091 12.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DASH_Dam1 PF08653.10 KUM58031.1 - 0.11 12.3 0.8 9.2 6.2 0.0 3.7 4 0 0 4 4 4 0 DASH complex subunit Dam1 CHASE9 PF17153.4 KUM58031.1 - 0.19 11.9 0.4 8.3 6.6 0.1 3.0 2 1 1 3 3 3 0 Periplasmic sensor domain, extracellular Filament PF00038.21 KUM58031.1 - 0.78 9.3 4.1 21 4.6 1.5 2.4 2 1 0 2 2 2 0 Intermediate filament protein DUF2626 PF11117.8 KUM58031.1 - 1.4 9.7 8.1 5.5 7.8 8.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2626) Tektin PF03148.14 KUM58031.1 - 3.5 6.3 7.1 6.3 5.4 0.5 2.8 2 1 1 3 3 3 0 Tektin family RNA_pol_3_Rpc31 PF11705.8 KUM58032.1 - 0.0043 17.3 26.9 0.0048 17.2 26.9 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 KUM58032.1 - 0.033 13.5 20.1 0.034 13.5 20.1 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KUM58032.1 - 0.048 11.9 23.6 0.05 11.8 23.6 1.2 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 KUM58032.1 - 0.28 10.8 19.1 0.34 10.5 19.1 1.3 1 0 0 1 1 1 0 PPP4R2 DDHD PF02862.17 KUM58032.1 - 0.3 11.2 2.7 0.37 10.9 2.7 1.2 1 0 0 1 1 1 0 DDHD domain SDA1 PF05285.12 KUM58032.1 - 0.44 9.9 25.5 0.47 9.8 25.5 1.1 1 0 0 1 1 1 0 SDA1 Spore_coat_CotO PF14153.6 KUM58032.1 - 0.59 10.0 20.8 0.73 9.7 20.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO RR_TM4-6 PF06459.12 KUM58032.1 - 0.81 9.5 15.1 0.88 9.3 15.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 KUM58032.1 - 1 8.3 7.4 1.2 8.0 7.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4820 PF16091.5 KUM58032.1 - 1.1 8.6 7.1 1.1 8.6 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF2151 PF10221.9 KUM58032.1 - 1.5 7.3 10.9 1.5 7.3 10.9 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator RP-C_C PF11800.8 KUM58032.1 - 2 8.5 9.3 2.5 8.1 9.3 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region SAPS PF04499.15 KUM58032.1 - 3.4 6.4 10.3 3.4 6.3 10.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Paf1 PF03985.13 KUM58032.1 - 3.8 6.4 26.9 4.4 6.2 26.9 1.1 1 0 0 1 1 1 0 Paf1 V_ATPase_I PF01496.19 KUM58032.1 - 6.3 4.6 9.3 6.1 4.6 9.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hid1 PF12722.7 KUM58032.1 - 8.9 4.3 8.2 9.7 4.2 8.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PH_6 PF15406.6 KUM58033.1 - 3.4e-37 127.2 4.2 3.4e-37 127.2 4.2 3.6 3 1 1 4 4 4 1 Pleckstrin homology domain PH PF00169.29 KUM58033.1 - 1.1e-07 32.3 0.0 5.4e-07 30.1 0.0 2.2 1 1 0 1 1 1 1 PH domain PH_4 PF15404.6 KUM58033.1 - 0.26 11.0 0.0 0.26 11.0 0.0 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain Ceramidase PF05875.12 KUM58034.1 - 3.3e-53 180.8 5.8 3.8e-53 180.6 5.8 1.0 1 0 0 1 1 1 1 Ceramidase Peptidase_U4 PF03419.13 KUM58034.1 - 0.88 8.8 5.1 2.6 7.2 5.1 1.7 1 1 0 1 1 1 0 Sporulation factor SpoIIGA Asn_synthase PF00733.21 KUM58035.1 - 5.2e-14 52.7 0.3 4e-06 26.7 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KUM58035.1 - 1.8e-06 27.9 0.0 1.1e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KUM58035.1 - 0.00078 19.0 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Aluminium induced protein GATase_6 PF13522.6 KUM58035.1 - 0.008 16.4 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain bZIP_2 PF07716.15 KUM58036.1 - 0.00019 21.4 8.4 0.00034 20.6 8.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper PKcGMP_CC PF16808.5 KUM58036.1 - 0.00019 21.2 3.0 0.00034 20.4 3.0 1.3 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 KUM58036.1 - 0.054 14.1 1.4 0.13 12.9 1.4 1.5 1 0 0 1 1 1 0 SlyX bZIP_1 PF00170.21 KUM58036.1 - 0.081 13.0 7.8 0.15 12.2 7.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor Abhydrolase_6 PF12697.7 KUM58037.1 - 1.2e-12 49.0 2.5 1.5e-12 48.6 1.8 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM58037.1 - 5.4e-07 29.1 0.0 8.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KUM58037.1 - 0.00013 21.8 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KUM58037.1 - 0.0064 16.2 0.5 0.013 15.2 0.1 1.7 2 0 0 2 2 2 1 PGAP1-like protein VPS9 PF02204.18 KUM58038.1 - 1e-29 102.8 0.0 1.8e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KUM58038.1 - 3.3e-15 56.1 0.6 8e-15 54.9 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KUM58038.1 - 3e-09 36.4 0.2 3.9e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 CUE domain Mito_carr PF00153.27 KUM58039.1 - 2.4e-50 168.4 3.5 1.3e-17 63.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF5333 PF17267.2 KUM58040.1 - 0.01 16.0 5.3 0.01 16.0 5.3 2.6 3 1 0 3 3 3 0 Family of unknown function (DUF5333) Menin PF05053.13 KUM58041.1 - 0.0069 14.8 8.7 0.0079 14.6 8.7 1.0 1 0 0 1 1 1 1 Menin MFS_1 PF07690.16 KUM58042.1 - 9.8e-18 64.2 45.7 5.1e-17 61.8 44.5 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily PetG PF02529.15 KUM58042.1 - 5.3 7.0 7.5 4.4 7.2 0.0 2.7 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 ketoacyl-synt PF00109.26 KUM58043.1 - 4.2e-70 236.2 0.0 7.2e-70 235.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KUM58043.1 - 1.6e-57 195.0 0.0 2.9e-57 194.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KUM58043.1 - 9.9e-55 185.2 0.2 2.2e-54 184.1 0.2 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KUM58043.1 - 7.9e-49 166.9 0.0 1.3e-48 166.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KUM58043.1 - 1.6e-33 115.2 0.1 7.8e-33 113.0 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KUM58043.1 - 2.5e-17 63.3 0.1 5.7e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KUM58043.1 - 3.5e-08 33.1 0.1 7.3e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.23 KUM58043.1 - 4.8e-06 26.1 0.1 1.9e-05 24.2 0.1 2.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KUM58043.1 - 0.0011 18.8 1.3 0.0063 16.3 1.3 2.4 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PP-binding PF00550.25 KUM58043.1 - 0.12 12.7 0.1 0.36 11.2 0.1 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site GMC_oxred_N PF00732.19 KUM58044.1 - 3.6e-59 200.5 0.0 4.7e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM58044.1 - 5.3e-35 121.0 0.0 1.1e-34 120.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KUM58044.1 - 2.6e-07 30.1 0.2 0.00095 18.3 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KUM58044.1 - 4e-06 27.0 0.5 2.1e-05 24.6 0.3 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM58044.1 - 3.8e-05 23.5 0.0 0.00054 19.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM58044.1 - 9.1e-05 21.8 0.0 0.076 12.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM58044.1 - 0.0014 17.9 0.6 1.3 8.3 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KUM58044.1 - 0.0033 16.7 0.0 0.0098 15.2 0.0 1.7 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KUM58044.1 - 0.013 14.2 0.3 0.078 11.7 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 KUM58044.1 - 0.017 15.1 0.4 0.65 10.0 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KUM58044.1 - 0.041 13.1 0.2 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KUM58044.1 - 0.075 12.1 0.1 3.6 6.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KUM58044.1 - 0.19 10.7 0.2 0.36 9.8 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Amidohydro_1 PF01979.20 KUM58045.1 - 1.5e-22 80.4 0.0 2.2e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KUM58045.1 - 6.1e-12 45.8 0.0 7.4e-06 25.7 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 KUM58045.1 - 0.043 14.2 0.1 0.087 13.2 0.1 1.4 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain Zn_clus PF00172.18 KUM58046.1 - 2.1e-06 27.8 9.9 4.5e-06 26.7 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM58046.1 - 0.00011 21.1 0.1 0.00013 20.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain LON_substr_bdg PF02190.16 KUM58047.1 - 5.7e-25 88.4 0.0 8.1e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KUM58047.1 - 1.2e-12 47.4 19.4 1.1e-11 44.3 10.3 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KUM58047.1 - 4.9e-11 42.3 15.8 2.5e-09 36.8 6.7 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KUM58047.1 - 2.1e-10 40.6 17.8 4e-06 26.9 8.1 2.6 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KUM58047.1 - 5.4e-10 39.1 16.9 9.1e-07 28.7 7.4 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 KUM58047.1 - 7.2e-10 38.7 20.1 2.6e-07 30.5 3.6 3.3 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_2 PF13639.6 KUM58047.1 - 4.2e-09 36.6 17.8 1.1e-07 32.0 8.5 2.6 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 KUM58047.1 - 2.7e-08 33.5 16.6 6.3e-07 29.2 8.5 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KUM58047.1 - 9.7e-07 28.5 15.9 2.6e-06 27.2 6.3 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KUM58047.1 - 0.00073 19.6 5.2 0.00073 19.6 5.2 2.4 2 0 0 2 2 2 1 zinc RING finger of MSL2 U-box PF04564.15 KUM58047.1 - 0.0025 18.0 0.1 0.0091 16.2 0.0 1.9 2 0 0 2 2 2 1 U-box domain zf-rbx1 PF12678.7 KUM58047.1 - 0.0027 17.9 4.2 0.0027 17.9 4.2 2.2 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KUM58047.1 - 0.0053 16.5 8.5 0.0069 16.2 5.4 2.5 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KUM58047.1 - 0.14 11.8 9.7 0.028 14.1 4.0 2.5 2 0 0 2 2 2 0 P-11 zinc finger zf-ANAPC11 PF12861.7 KUM58047.1 - 0.16 12.1 2.4 1.4 9.0 1.9 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KUM58047.1 - 0.37 10.7 10.0 1.1 9.2 2.5 2.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C2HC_2 PF13913.6 KUM58047.1 - 5.3 7.1 7.5 2.5 8.1 0.5 2.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Rad9 PF04139.13 KUM58048.1 - 1.9e-51 174.9 1.3 2.4e-51 174.6 1.3 1.1 1 0 0 1 1 1 1 Rad9 DUF2218 PF09981.9 KUM58048.1 - 0.066 13.6 0.4 0.44 11.0 0.1 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) PCC_BT PF18140.1 KUM58048.1 - 0.11 12.9 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain RCC1 PF00415.18 KUM58049.1 - 1.7e-34 118.2 14.5 2.5e-08 34.4 0.0 7.1 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KUM58049.1 - 3.3e-17 61.8 23.4 1.7e-06 27.6 0.8 6.9 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Sugar_tr PF00083.24 KUM58050.1 - 2.8e-26 92.4 21.8 7.1e-24 84.5 21.8 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter FlgT_N PF16548.5 KUM58052.1 - 0.26 11.9 1.1 11 6.6 1.1 2.4 1 1 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain Barstar PF01337.18 KUM58052.1 - 4.7 7.3 6.5 4.9e+02 0.8 6.5 3.0 1 1 0 1 1 1 0 Barstar (barnase inhibitor) MMS1_N PF10433.9 KUM58054.1 - 1.1e-130 436.6 0.0 1.6e-130 436.1 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KUM58054.1 - 1.1e-76 258.2 0.0 2.8e-74 250.3 0.0 3.5 4 0 0 4 4 4 1 CPSF A subunit region PQQ_2 PF13360.6 KUM58054.1 - 0.00051 19.7 0.2 0.004 16.8 0.0 2.4 2 1 1 3 3 3 1 PQQ-like domain FAD_binding_1 PF00667.20 KUM58055.1 - 1.5e-63 214.3 0.0 2.3e-63 213.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KUM58055.1 - 3.1e-35 121.5 1.7 5.9e-35 120.6 1.7 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KUM58055.1 - 3.2e-19 69.6 0.0 4.7e-18 65.8 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KUM58055.1 - 0.14 12.4 0.1 0.48 10.7 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin domain TatD_DNase PF01026.21 KUM58056.1 - 6.9e-46 156.7 0.0 7.9e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase BKACE PF05853.12 KUM58056.1 - 0.063 12.6 0.0 0.08 12.2 0.0 1.3 1 1 0 1 1 1 0 beta-keto acid cleavage enzyme tRNA_synt_1c_R2 PF04557.15 KUM58057.1 - 4.7 8.2 7.5 1.1 10.3 0.5 2.4 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 MARVEL PF01284.23 KUM58059.1 - 0.072 13.1 14.3 0.51 10.4 15.3 1.7 1 1 1 2 2 2 0 Membrane-associating domain PGA2 PF07543.12 KUM58060.1 - 2.2e-44 150.8 3.5 2.9e-44 150.4 3.5 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 RNA_pol_Rpb2_5 PF04567.17 KUM58060.1 - 2.4 8.8 4.8 1.3 9.6 1.0 2.4 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 5 NAD_binding_2 PF03446.15 KUM58061.1 - 1.9e-31 109.4 0.2 3e-31 108.7 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KUM58061.1 - 1.7e-29 102.6 0.0 3.1e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 KUM58061.1 - 0.013 14.9 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TGS PF02824.21 KUM58061.1 - 0.028 14.5 0.0 0.091 12.8 0.0 1.9 1 0 0 1 1 1 0 TGS domain Tim17 PF02466.19 KUM58061.1 - 0.058 13.8 0.2 0.13 12.6 0.2 1.6 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family F420_oxidored PF03807.17 KUM58061.1 - 0.08 13.5 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MOR2-PAG1_N PF14222.6 KUM58062.1 - 1.9e-209 697.3 0.0 3.1e-209 696.5 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KUM58062.1 - 3.8e-90 302.2 0.0 1.4e-89 300.3 0.0 2.1 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KUM58062.1 - 1e-34 119.5 13.2 1e-12 46.6 0.2 4.0 2 1 1 3 3 3 3 Cell morphogenesis central region Bac_rhamnosid6H PF17389.2 KUM58063.1 - 6.2e-123 410.4 0.0 8.3e-123 410.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KUM58063.1 - 1.6e-52 177.8 0.0 2.5e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KUM58063.1 - 3.4e-22 78.4 0.0 2e-21 75.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KUM58063.1 - 6.1e-14 51.6 0.0 4.2e-12 45.7 0.0 3.0 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Sugar_tr PF00083.24 KUM58064.1 - 3.7e-83 279.9 16.5 4.4e-83 279.6 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM58064.1 - 2.6e-28 99.0 20.5 3.4e-28 98.6 20.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KUM58065.1 - 1.4e-05 24.3 0.1 1.7e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Alpha-L-AF_C PF06964.12 KUM58066.1 - 9e-15 55.2 0.7 1.6e-14 54.4 0.7 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Cpn60_TCP1 PF00118.24 KUM58067.1 - 2e-172 574.2 0.3 2.3e-172 574.0 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 KUM58067.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 BRK domain DUF1168 PF06658.12 KUM58068.1 - 9e-39 132.4 8.2 1.3e-38 131.9 8.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) PPL5 PF18168.1 KUM58068.1 - 0.21 10.9 3.4 0.26 10.6 3.4 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Peptidase_S49_N PF08496.10 KUM58068.1 - 0.23 11.5 4.6 0.33 11.0 4.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.12 KUM58068.1 - 0.39 10.5 6.2 0.54 10.0 6.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KUM58068.1 - 1.2 7.4 8.3 1.5 7.0 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Med19 PF10278.9 KUM58068.1 - 2 8.3 13.7 3 7.7 13.7 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Presenilin PF01080.17 KUM58068.1 - 2.1 7.0 5.0 2.6 6.7 5.0 1.1 1 0 0 1 1 1 0 Presenilin DUF1682 PF07946.14 KUM58068.1 - 4.6 6.3 11.8 5.9 6.0 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) BCS1_N PF08740.11 KUM58069.1 - 6.9e-48 163.1 0.2 9.9e-48 162.6 0.2 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KUM58069.1 - 4.5e-18 65.9 0.0 8.9e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KUM58069.1 - 8.4e-05 23.0 0.1 0.00039 20.8 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KUM58069.1 - 0.00068 18.9 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KUM58069.1 - 0.0014 18.4 0.0 0.045 13.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KUM58069.1 - 0.0014 18.1 0.0 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 KUM58069.1 - 0.0056 17.2 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KUM58069.1 - 0.0083 15.7 0.0 0.17 11.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 KUM58069.1 - 0.0083 16.5 0.0 0.027 14.8 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_5 PF07728.14 KUM58069.1 - 0.0085 16.1 0.0 0.026 14.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KUM58069.1 - 0.019 14.7 0.0 0.052 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KUM58069.1 - 0.023 15.2 0.0 0.058 13.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 KUM58069.1 - 0.029 14.2 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KUM58069.1 - 0.033 14.5 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 KUM58069.1 - 0.045 13.9 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2735 PF10931.8 KUM58069.1 - 0.072 13.8 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) MMR_HSR1 PF01926.23 KUM58069.1 - 0.075 13.1 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATPase PF06745.13 KUM58069.1 - 0.077 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC PPV_E1_C PF00519.17 KUM58069.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase RuvB_N PF05496.12 KUM58069.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KUM58069.1 - 0.14 12.0 0.0 0.33 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KUM58069.1 - 0.17 11.8 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Lactamase_B_2 PF12706.7 KUM58070.1 - 4.3e-28 98.2 0.0 4.1e-27 95.0 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KUM58070.1 - 8.4e-11 42.0 0.0 3.6e-10 40.0 0.0 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KUM58070.1 - 0.00082 19.4 0.8 0.18 11.8 0.6 3.1 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily BTB PF00651.31 KUM58071.1 - 1.3e-06 28.6 0.0 9e-06 25.9 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain COX7B PF05392.11 KUM58071.1 - 0.2 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB zf-PARP PF00645.18 KUM58072.1 - 4.9e-22 78.6 2.1 6.4e-22 78.2 0.2 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AT_hook PF02178.19 KUM58072.1 - 0.43 10.6 7.6 0.17 11.9 2.5 3.4 2 0 0 2 2 2 0 AT hook motif PRR18 PF15671.5 KUM58073.1 - 0.36 10.7 7.1 0.057 13.3 3.0 1.6 2 0 0 2 2 2 0 Proline-rich protein family 18 FAM176 PF14851.6 KUM58073.1 - 1.7 8.3 3.3 3 7.5 3.3 1.3 1 0 0 1 1 1 0 FAM176 family Astro_capsid_p PF12226.8 KUM58073.1 - 4.2 6.4 5.0 6.5 5.8 5.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-B_dimeris PF09026.10 KUM58073.1 - 8.2 6.9 12.4 17 5.8 12.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF5305 PF17231.2 KUM58074.1 - 0.041 13.3 0.1 0.051 13.0 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) ABM PF03992.16 KUM58075.1 - 4e-05 23.6 0.0 5.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SelP_N PF04592.14 KUM58075.1 - 0.017 14.5 0.2 0.02 14.3 0.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FemAB_like PF04339.12 KUM58075.1 - 0.029 13.5 0.1 0.033 13.3 0.1 1.0 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition IPPT PF01715.17 KUM58078.1 - 1.5e-60 204.8 0.8 2.5e-60 204.1 0.8 1.3 1 0 0 1 1 1 1 IPP transferase zf-met PF12874.7 KUM58078.1 - 5.9e-07 29.7 3.2 1e-06 28.9 3.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KUM58078.1 - 8.4e-06 25.9 5.8 1.4e-05 25.2 5.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KUM58078.1 - 0.016 15.5 2.4 0.043 14.2 2.4 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Ring_hydroxyl_A PF00848.19 KUM58078.1 - 0.031 14.3 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) zf-C2H2_4 PF13894.6 KUM58078.1 - 0.077 13.9 0.5 0.16 12.9 0.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger B12-binding PF02310.19 KUM58078.1 - 0.098 12.7 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 B12 binding domain Aminotran_5 PF00266.19 KUM58079.1 - 9.3e-29 100.5 0.0 7.5e-18 64.6 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class-V DUF4328 PF14219.6 KUM58079.1 - 0.0042 16.7 0.0 0.018 14.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4328) NAD_binding_1 PF00175.21 KUM58080.1 - 1e-09 39.0 0.0 0.00047 20.8 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KUM58080.1 - 7.4e-05 23.0 0.0 0.00027 21.2 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KUM58080.1 - 0.00037 20.7 0.0 0.0017 18.5 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain AA_permease_2 PF13520.6 KUM58081.1 - 9.5e-60 202.6 40.2 1.9e-59 201.6 40.2 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM58081.1 - 1.5e-26 93.0 24.4 1.5e-26 93.0 24.4 2.2 2 0 0 2 2 2 2 Amino acid permease NADHdeh_related PF10125.9 KUM58081.1 - 0.45 9.9 11.0 0.023 14.1 4.7 2.0 2 0 0 2 2 2 0 NADH dehydrogenase I, subunit N related protein Glyco_hydro_32N PF00251.20 KUM58082.1 - 4e-46 158.0 0.0 6.1e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KUM58082.1 - 5.3e-24 85.0 0.0 8.1e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.20 KUM58082.1 - 0.0073 16.1 1.4 0.19 11.9 0.0 3.2 2 0 0 2 2 2 1 BNR/Asp-box repeat CC2D2AN-C2 PF15625.6 KUM58082.1 - 0.056 13.2 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 CC2D2A N-terminal C2 domain DUF4975 PF16346.5 KUM58082.1 - 0.082 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) Pkinase PF00069.25 KUM58083.1 - 1.1e-43 149.5 0.0 1.7e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM58083.1 - 1.8e-26 93.0 0.0 3.1e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.6 KUM58083.1 - 1.9e-10 40.9 0.3 0.00011 22.4 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 KUM58083.1 - 5.5e-05 22.5 4.0 0.058 12.6 0.1 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KUM58083.1 - 0.00039 21.0 0.7 4.1 8.1 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM58083.1 - 0.0006 20.0 0.7 0.035 14.3 0.5 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Kinase-like PF14531.6 KUM58083.1 - 0.0047 16.3 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like TPR_2 PF07719.17 KUM58083.1 - 0.011 15.7 10.5 5.6 7.3 0.5 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KUM58083.1 - 0.013 15.6 2.2 1.5 9.3 0.6 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat MF_alpha_N PF05436.11 KUM58083.1 - 0.02 14.8 0.0 3.7 7.5 0.0 2.5 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus TPR_19 PF14559.6 KUM58083.1 - 0.037 14.5 1.1 1.3 9.6 0.4 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KUM58083.1 - 0.073 13.1 2.0 8.4 6.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KUM58083.1 - 0.55 10.1 9.0 19 5.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 KUM58084.1 - 1.1e-07 31.6 0.0 1.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM58084.1 - 0.00021 20.7 0.0 0.00084 18.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Sugar_tr PF00083.24 KUM58085.1 - 5.7e-81 272.7 12.2 7.1e-81 272.4 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM58085.1 - 8.1e-22 77.6 32.5 6.5e-20 71.3 15.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PMT_4TMC PF16192.5 KUM58085.1 - 0.27 10.8 4.3 0.8 9.3 4.3 1.9 1 1 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase Fungal_trans PF04082.18 KUM58086.1 - 6e-08 32.0 1.4 6.9e-08 31.8 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain HapK PF11639.8 KUM58086.1 - 0.017 15.6 0.0 0.033 14.7 0.0 1.5 1 0 0 1 1 1 0 REDY-like protein HapK Amidase PF01425.21 KUM58087.1 - 6.4e-103 345.1 0.0 8.3e-103 344.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Imm49 PF15575.6 KUM58088.1 - 0.04 13.7 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 49 Rep_fac_C PF08542.11 KUM58089.1 - 3.2e-22 78.7 0.0 1.7e-21 76.4 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KUM58089.1 - 2.7e-12 46.8 0.0 4.5e-09 36.3 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 KUM58089.1 - 6e-11 42.9 0.0 1e-10 42.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KUM58089.1 - 1.1e-06 28.7 0.0 3.7e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KUM58089.1 - 5.3e-06 26.9 0.0 0.00045 20.6 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KUM58089.1 - 1.9e-05 24.5 0.0 3.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KUM58089.1 - 0.00016 21.5 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KUM58089.1 - 0.00019 21.3 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KUM58089.1 - 0.00021 21.6 0.1 0.63 10.3 0.1 2.4 1 1 1 2 2 2 2 AAA domain DNA_pol3_delta PF06144.13 KUM58089.1 - 0.00091 19.0 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KUM58089.1 - 0.0041 17.1 0.0 0.008 16.1 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 KUM58089.1 - 0.0049 16.3 0.1 0.066 12.6 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KUM58089.1 - 0.0082 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KUM58089.1 - 0.0097 14.9 0.0 0.018 14.0 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TniB PF05621.11 KUM58089.1 - 0.0098 15.3 0.1 4.3 6.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein AAA_assoc_2 PF16193.5 KUM58089.1 - 0.026 14.9 0.0 0.079 13.3 0.0 1.8 2 0 0 2 2 1 0 AAA C-terminal domain NTPase_1 PF03266.15 KUM58089.1 - 0.031 14.2 0.2 0.14 12.1 0.1 2.0 1 1 1 2 2 2 0 NTPase AAA_19 PF13245.6 KUM58089.1 - 0.031 14.6 0.2 0.08 13.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 KUM58089.1 - 0.039 13.4 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_25 PF13481.6 KUM58089.1 - 0.054 13.1 0.1 0.25 10.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KUM58089.1 - 0.059 13.1 0.1 0.15 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 KUM58089.1 - 0.06 13.1 0.1 1.9 8.2 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_24 PF13479.6 KUM58089.1 - 0.062 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RGS12_usC PF16612.5 KUM58089.1 - 0.2 12.1 0.0 0.32 11.4 0.0 1.3 1 0 0 1 1 1 0 C-terminal unstructured region of RGS12 RAI1 PF08652.11 KUM58090.1 - 1.6e-28 98.7 0.0 3.1e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Tox-REase-3 PF15647.6 KUM58090.1 - 0.098 12.9 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 DUF410 PF04190.13 KUM58091.1 - 5.2e-88 295.1 0.0 6.3e-88 294.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) ABC_tran PF00005.27 KUM58092.1 - 7.7e-17 62.1 0.2 8.3e-16 58.8 0.2 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KUM58092.1 - 8.4e-11 42.2 3.2 5.7e-05 23.1 0.7 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KUM58092.1 - 0.0013 18.2 0.1 0.53 9.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KUM58092.1 - 0.0015 18.2 0.3 0.0027 17.4 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain PduV-EutP PF10662.9 KUM58092.1 - 0.0019 18.0 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 KUM58092.1 - 0.004 16.8 0.0 0.0082 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF3584 PF12128.8 KUM58092.1 - 0.0043 14.7 0.6 0.0059 14.2 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_16 PF13191.6 KUM58092.1 - 0.0089 16.4 0.7 0.019 15.3 0.7 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KUM58092.1 - 0.012 16.1 0.4 0.02 15.4 0.4 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KUM58092.1 - 0.018 15.3 0.5 0.063 13.5 0.3 1.9 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KUM58092.1 - 0.024 14.3 0.1 0.036 13.8 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KUM58092.1 - 0.04 13.8 0.1 0.064 13.2 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase Roc PF08477.13 KUM58092.1 - 0.11 12.7 0.1 0.37 11.0 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 KUM58092.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 KUM58092.1 - 0.13 10.9 0.1 0.18 10.5 0.1 1.1 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 KUM58092.1 - 0.13 11.0 0.1 0.2 10.4 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 KUM58092.1 - 0.14 12.5 0.6 0.34 11.2 0.6 1.9 1 1 0 1 1 1 0 AAA domain Arf PF00025.21 KUM58092.1 - 0.14 11.6 0.1 0.32 10.4 0.1 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family ATPase PF06745.13 KUM58092.1 - 0.16 11.3 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 KUM58092.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KUM58092.1 - 0.19 12.1 0.1 0.97 9.9 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pro_isomerase PF00160.21 KUM58093.1 - 7.4e-47 159.5 0.5 1e-46 159.1 0.5 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FixS PF03597.15 KUM58093.1 - 0.068 12.9 2.4 0.54 10.0 0.0 2.4 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DEAD PF00270.29 KUM58094.1 - 1.4e-47 161.7 0.0 4.8e-47 160.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM58094.1 - 1e-32 112.7 0.0 2.8e-32 111.3 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM58094.1 - 0.0075 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KUM58094.1 - 0.047 13.0 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KUM58094.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 KUM58094.1 - 0.29 9.8 0.0 0.48 9.1 0.0 1.2 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF4419 PF14388.6 KUM58095.1 - 2.3e-102 342.5 0.0 2.7e-102 342.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) RTA1 PF04479.13 KUM58096.1 - 1.8e-61 207.4 9.1 2.4e-61 206.9 9.1 1.2 1 0 0 1 1 1 1 RTA1 like protein Myb_DNA-bind_6 PF13921.6 KUM58097.1 - 2.6e-17 62.8 0.2 8.6e-17 61.1 0.2 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSA PF07529.13 KUM58097.1 - 1.1e-14 54.5 0.2 1.1e-14 54.5 0.2 4.1 4 0 0 4 4 4 1 HSA Myb_DNA-binding PF00249.31 KUM58097.1 - 4.8e-05 23.5 2.5 0.00063 19.9 0.3 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain WD40 PF00400.32 KUM58098.1 - 7.6e-11 42.4 0.0 0.16 12.9 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 KUM58098.1 - 0.039 13.2 0.0 0.083 12.1 0.0 1.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Peptidase_M16_C PF05193.21 KUM58099.1 - 8.9e-14 51.9 0.0 1e-10 42.0 0.0 3.0 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KUM58099.1 - 2.8e-06 27.4 0.0 7.8e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) GCIP PF13324.6 KUM58099.1 - 0.24 11.0 5.4 0.54 9.8 5.4 1.6 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Pes-10 PF07149.11 KUM58099.1 - 1.2 8.1 5.5 2.2 7.3 5.5 1.4 1 0 0 1 1 1 0 Pes-10 Astro_capsid_p PF12226.8 KUM58099.1 - 2.6 7.1 11.1 5.1 6.1 11.1 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Sigma70_ner PF04546.13 KUM58099.1 - 3.7 7.4 12.9 2.7 7.8 6.7 2.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.11 KUM58099.1 - 9.6 4.1 7.9 13 3.7 7.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Zw10 PF06248.13 KUM58100.1 - 2.1e-12 46.4 0.6 2.1e-12 46.4 0.6 1.9 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 KUM58100.1 - 3.9e-07 30.0 0.0 9.2e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal BUD22 PF09073.10 KUM58100.1 - 0.45 9.8 21.3 0.98 8.7 21.3 1.4 1 0 0 1 1 1 0 BUD22 WD40 PF00400.32 KUM58101.1 - 2.9e-22 78.5 15.0 4.8e-07 30.4 0.2 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 KUM58101.1 - 5.7e-20 71.6 0.2 1.1e-19 70.6 0.2 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KUM58101.1 - 3.6e-06 25.9 0.4 0.00045 19.0 0.1 2.7 1 1 0 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KUM58101.1 - 0.085 13.2 0.0 3.1 8.2 0.0 3.0 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S13 PF00416.22 KUM58102.1 - 4.1e-21 75.7 0.4 7e-19 68.5 0.4 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Ntox8 PF15545.6 KUM58102.1 - 0.016 15.3 0.2 0.024 14.7 0.2 1.3 1 0 0 1 1 1 0 Bacterial toxin 8 eIF2_C PF09173.11 KUM58103.1 - 1.4e-34 118.2 0.4 3.4e-34 116.9 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KUM58103.1 - 6.4e-23 81.3 0.1 3.2e-22 79.0 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KUM58103.1 - 1.8e-12 47.4 0.2 4.3e-12 46.2 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KUM58103.1 - 0.011 15.7 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 KUM58103.1 - 0.012 15.6 0.0 0.032 14.3 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Peptidase_M48_N PF16491.5 KUM58104.1 - 3.4e-65 219.3 7.3 3.4e-65 219.3 7.3 1.8 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KUM58104.1 - 1.2e-45 155.7 0.3 2.1e-45 154.9 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M48 DUF4538 PF15061.6 KUM58104.1 - 0.08 12.7 1.1 0.21 11.3 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) RNA_polI_A14 PF08203.11 KUM58105.1 - 0.0074 17.0 0.1 0.022 15.4 0.0 1.8 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 Ribosomal_L34 PF00468.17 KUM58106.1 - 1.2e-12 47.6 11.9 1.2e-12 47.6 11.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L34 PPR_2 PF13041.6 KUM58107.1 - 1.1e-22 79.9 0.1 1.8e-16 60.0 0.0 3.1 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 KUM58107.1 - 8.2e-10 38.6 0.0 0.00034 20.6 0.0 3.0 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 KUM58107.1 - 0.00058 19.9 0.0 0.11 12.8 0.0 3.6 3 0 0 3 3 3 1 PPR repeat PPR_long PF17177.4 KUM58107.1 - 0.034 13.5 0.0 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KUM58107.1 - 0.27 10.9 1.9 28 4.5 0.0 3.6 4 0 0 4 4 4 0 PPR repeat DEAD PF00270.29 KUM58109.1 - 9.7e-26 90.6 0.0 1.9e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KUM58109.1 - 2.2e-18 66.8 0.1 6.5e-18 65.3 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KUM58109.1 - 8.6e-13 48.6 0.1 2.5e-12 47.1 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.11 KUM58109.1 - 1.1e-07 32.4 0.0 2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.15 KUM58109.1 - 0.00026 21.1 0.0 0.00046 20.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_S10 PF00450.22 KUM58110.1 - 1.2e-58 199.5 4.0 1.5e-58 199.2 4.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Yip1 PF04893.17 KUM58111.1 - 1.8e-11 44.1 17.2 3.2e-11 43.2 17.2 1.5 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KUM58111.1 - 0.086 12.6 6.6 0.13 12.0 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF2070 PF09843.9 KUM58111.1 - 4 5.6 10.7 5 5.3 10.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ran_BP1 PF00638.18 KUM58112.1 - 3.9e-17 62.6 0.1 5.9e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 RanBP1 domain Keratin_B2_2 PF13885.6 KUM58112.1 - 0.15 12.0 2.7 1.2 9.1 2.7 2.2 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein Fungal_trans_2 PF11951.8 KUM58113.1 - 7.7e-12 44.7 1.0 1.5e-11 43.7 1.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM58113.1 - 2.1e-07 31.0 10.0 3.4e-07 30.3 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_2 PF00891.18 KUM58114.1 - 3.1e-20 72.4 0.0 5e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KUM58114.1 - 0.026 14.5 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain HemN_C PF06969.16 KUM58114.1 - 0.14 12.2 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 HemN C-terminal domain ZapB PF06005.12 KUM58115.1 - 0.098 13.1 0.2 0.15 12.5 0.2 1.2 1 0 0 1 1 1 0 Cell division protein ZapB Bac_luciferase PF00296.20 KUM58116.1 - 1.4e-24 87.1 0.0 1.8e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Con-6 PF10346.9 KUM58118.1 - 0.0012 18.8 0.1 0.0023 17.9 0.1 1.5 1 0 0 1 1 1 1 Conidiation protein 6 Hemerythrin PF01814.23 KUM58119.1 - 3.8e-13 50.2 3.9 3.9e-13 50.2 2.9 1.5 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain Qua1 PF16274.5 KUM58119.1 - 0.054 13.3 0.2 13 5.8 0.0 2.7 3 0 0 3 3 3 0 Qua1 domain RTA1 PF04479.13 KUM58120.1 - 2.9e-55 187.1 8.8 3.3e-55 186.9 8.8 1.0 1 0 0 1 1 1 1 RTA1 like protein IFS PF16718.5 KUM58120.1 - 0.09 12.9 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Immunity factor for SPN PRK PF00485.18 KUM58121.1 - 8.8e-07 28.8 0.1 2.4e-05 24.2 0.1 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KUM58121.1 - 2.1e-06 28.3 0.0 2.1e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KUM58121.1 - 3.9e-05 23.8 0.0 0.00072 19.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KUM58121.1 - 0.00043 20.0 0.0 0.00065 19.4 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA PF00004.29 KUM58121.1 - 0.00064 20.2 0.0 0.00094 19.6 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KUM58121.1 - 0.00068 19.0 0.0 0.0017 17.7 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 KUM58121.1 - 0.00091 19.6 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KUM58121.1 - 0.00096 19.4 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KUM58121.1 - 0.0017 18.8 0.0 0.01 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KUM58121.1 - 0.0029 17.3 0.0 0.078 12.6 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase KTI12 PF08433.10 KUM58121.1 - 0.0034 16.9 0.0 0.0045 16.5 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 T2SSE PF00437.20 KUM58121.1 - 0.005 15.9 0.0 0.0073 15.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein MeaB PF03308.16 KUM58121.1 - 0.0055 15.7 0.0 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KUM58121.1 - 0.0081 15.9 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KUM58121.1 - 0.012 16.0 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KUM58121.1 - 0.029 14.3 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.20 KUM58121.1 - 0.034 14.1 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 KUM58121.1 - 0.04 13.8 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 KUM58121.1 - 0.044 13.0 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 KUM58121.1 - 0.057 12.7 0.0 0.074 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KUM58121.1 - 0.075 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MobB PF03205.14 KUM58121.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 KUM58121.1 - 0.12 12.1 0.1 0.4 10.4 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_11 PF13086.6 KUM58121.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KUM58121.1 - 0.18 11.5 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KUM58121.1 - 0.21 11.3 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF1899 PF08953.11 KUM58122.1 - 2.2e-33 113.9 0.0 4.8e-33 112.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KUM58122.1 - 4.8e-20 71.2 0.1 1e-19 70.2 0.1 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KUM58122.1 - 1.9e-17 63.3 4.6 0.00033 21.4 0.2 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM58122.1 - 3.7e-06 27.2 0.0 0.038 14.3 0.0 3.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KUM58122.1 - 0.00058 18.6 0.2 0.24 10.0 0.2 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DivIC PF04977.15 KUM58122.1 - 0.038 13.7 0.8 0.077 12.8 0.8 1.4 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 KUM58122.1 - 0.095 13.3 2.6 0.12 13.0 1.3 1.8 2 0 0 2 2 2 0 SlyX eIF3_subunit PF08597.10 KUM58122.1 - 2.1 8.2 8.1 1.5 8.7 5.1 1.9 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit Lipase_3 PF01764.25 KUM58123.1 - 2.4e-19 69.6 0.0 3.6e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KUM58123.1 - 0.12 12.9 10.3 0.32 11.6 9.3 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family MFS_1 PF07690.16 KUM58125.1 - 9.8e-15 54.3 16.8 9.8e-15 54.3 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KUM58125.1 - 0.0077 14.6 0.0 0.0077 14.6 0.0 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF202 PF02656.15 KUM58125.1 - 0.18 12.3 0.0 0.18 12.3 0.0 3.5 3 2 0 3 3 3 0 Domain of unknown function (DUF202) RAI16-like PF10257.9 KUM58126.1 - 1.3e-84 284.2 0.0 1.9e-84 283.6 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein TMEM51 PF15345.6 KUM58126.1 - 0.093 12.6 0.2 0.17 11.7 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 CBFD_NFYB_HMF PF00808.23 KUM58127.1 - 5.9e-16 58.5 2.1 9.3e-16 57.9 2.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KUM58127.1 - 2.7e-05 24.6 0.8 2.7e-05 24.6 0.8 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 zf-C3HC4_3 PF13920.6 KUM58128.1 - 0.00051 19.8 12.1 0.00089 19.1 12.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 KUM58128.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 U-box domain FAD_binding_4 PF01565.23 KUM58129.1 - 2.2e-25 89.0 1.9 3.7e-25 88.3 1.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KUM58129.1 - 5.1e-14 52.1 0.0 1.4e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Abhydrolase_1 PF00561.20 KUM58131.1 - 7.8e-23 81.4 0.0 1.6e-21 77.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM58131.1 - 1.4e-12 47.4 0.0 2.7e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KUM58131.1 - 1.4e-11 45.4 0.1 1.8e-11 45.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KUM58131.1 - 0.00083 18.1 0.0 0.0014 17.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 KUM58131.1 - 0.0037 17.4 0.0 0.0076 16.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Thioesterase PF00975.20 KUM58131.1 - 0.0047 17.1 0.0 0.031 14.4 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 KUM58131.1 - 0.025 14.5 0.0 8 6.3 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase Palm_thioest PF02089.15 KUM58131.1 - 0.091 12.6 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF915 PF06028.11 KUM58131.1 - 0.098 12.0 0.0 0.25 10.6 0.0 1.5 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Kinesin PF00225.23 KUM58132.1 - 7.1e-106 353.9 0.8 1.4e-105 352.9 0.8 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KUM58132.1 - 2.3e-60 202.9 0.0 5.5e-60 201.6 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 KUM58132.1 - 0.0036 17.7 3.1 0.0051 17.2 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KUM58132.1 - 0.0061 16.5 4.0 0.43 10.4 0.0 2.7 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 KUM58132.1 - 0.03 14.2 1.3 0.062 13.1 0.0 2.2 3 0 0 3 3 3 0 Bacterial dnaA protein Tropomyosin_1 PF12718.7 KUM58132.1 - 0.035 14.3 17.3 0.055 13.6 16.1 2.0 1 1 0 1 1 1 0 Tropomyosin like GIT1_C PF12205.8 KUM58132.1 - 0.56 10.3 5.5 0.97 9.6 0.5 2.9 3 0 0 3 3 2 0 G protein-coupled receptor kinase-interacting protein 1 C term AAA_22 PF13401.6 KUM58132.1 - 0.86 9.9 9.0 0.26 11.5 0.2 3.1 2 2 0 2 2 2 0 AAA domain HIP1_clath_bdg PF16515.5 KUM58132.1 - 1.8 9.2 32.3 0.46 11.1 3.1 4.7 2 2 3 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 KUM58132.1 - 2.6 8.1 13.2 1.3 9.1 2.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Filament PF00038.21 KUM58132.1 - 4.5 6.8 25.4 1.5 8.4 14.3 3.7 2 1 1 3 3 3 0 Intermediate filament protein BST2 PF16716.5 KUM58132.1 - 5.1 7.8 14.4 0.36 11.4 2.4 3.6 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 CENP-F_leu_zip PF10473.9 KUM58132.1 - 6.4 6.8 23.7 72 3.4 0.1 3.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Zeta_toxin PF06414.12 KUM58132.1 - 8.4 5.6 9.1 1.5 8.0 0.0 3.5 3 2 0 4 4 4 0 Zeta toxin IF-2B PF01008.17 KUM58133.1 - 1.5e-17 63.7 0.0 4.2e-17 62.3 0.0 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.28 KUM58133.1 - 8.3e-13 48.5 0.2 1.5e-12 47.6 0.2 1.4 1 0 0 1 1 1 1 NUDIX domain p450 PF00067.22 KUM58134.1 - 3.3e-45 154.7 0.0 7.6e-45 153.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 KUM58135.1 - 1.2e-30 106.8 0.0 1.8e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM58135.1 - 3.4e-11 43.4 0.0 5.2e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KUM58135.1 - 4.3e-07 29.6 0.0 6.1e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KUM58135.1 - 6.8e-07 28.6 0.0 1.3e-06 27.6 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KUM58135.1 - 0.0077 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Zn_clus PF00172.18 KUM58136.1 - 3e-09 36.8 11.1 7.5e-09 35.6 11.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 KUM58137.1 - 2.2e-183 610.0 0.8 2.5e-183 609.8 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_N PF08240.12 KUM58138.1 - 2.4e-29 101.4 1.3 4.7e-29 100.5 1.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM58138.1 - 4.7e-22 78.4 0.3 7.4e-22 77.7 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM58138.1 - 0.00055 21.0 0.0 0.00088 20.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KUM58138.1 - 0.0035 16.7 0.2 0.0058 16.0 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KUM58138.1 - 0.024 13.9 1.0 0.038 13.3 1.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KUM58138.1 - 0.034 13.6 0.4 0.055 12.9 0.4 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Gpr1_Fun34_YaaH PF01184.19 KUM58139.1 - 1.3e-29 103.3 21.1 1.5e-29 103.1 21.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Ank_2 PF12796.7 KUM58140.1 - 3e-41 139.9 0.0 1.1e-09 38.7 0.0 7.9 5 4 4 9 9 9 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KUM58140.1 - 2.7e-29 98.0 8.6 0.0095 16.4 0.0 13.1 15 0 0 15 15 15 6 Ankyrin repeat Ank_4 PF13637.6 KUM58140.1 - 4.7e-28 97.2 1.4 1.7e-05 25.3 0.0 9.8 5 4 3 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM58140.1 - 5e-24 84.0 6.9 0.052 13.9 0.0 11.2 9 2 3 12 12 12 8 Ankyrin repeats (many copies) Ank PF00023.30 KUM58140.1 - 9.4e-22 76.5 6.8 0.00074 19.9 0.0 11.2 11 0 0 11 11 11 5 Ankyrin repeat TAD2 PF18521.1 KUM58141.1 - 0.11 12.5 0.4 0.43 10.6 0.4 2.0 1 0 0 1 1 1 0 Transactivation domain 2 GST_N_2 PF13409.6 KUM58142.1 - 8e-10 38.9 0.0 1.3e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KUM58142.1 - 4.3e-09 36.6 0.0 8.6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KUM58142.1 - 0.00052 20.0 0.1 0.003 17.5 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KUM58142.1 - 0.03 14.5 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KUM58142.1 - 0.035 14.3 0.0 0.084 13.1 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain His_Phos_1 PF00300.22 KUM58144.1 - 0.0039 16.9 0.0 0.0057 16.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SURF6 PF04935.12 KUM58145.1 - 4.4e-49 167.0 33.8 4.4e-49 167.0 33.8 4.0 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 KUM58145.1 - 1.9e-17 63.6 1.1 1.9e-17 63.6 1.1 8.5 7 2 0 7 7 7 1 60S ribosome biogenesis protein Rrp14 Ribosomal_S2 PF00318.20 KUM58146.1 - 7.6e-66 221.4 0.1 9.9e-65 217.8 0.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S2 BBE PF08031.12 KUM58146.1 - 0.077 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like Rick_17kDa_Anti PF05433.15 KUM58147.1 - 5.9e-06 26.1 13.6 1.4e-05 24.9 13.6 1.7 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KUM58147.1 - 0.014 15.4 12.4 0.041 13.9 12.4 1.9 1 0 0 1 1 1 0 Glycine zipper PT-VENN PF04829.13 KUM58147.1 - 1 9.5 4.9 1.7 8.8 4.9 1.3 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Transgly_assoc PF04226.13 KUM58147.1 - 1.9 8.8 11.6 3.3 8.0 11.6 1.4 1 0 0 1 1 1 0 Transglycosylase associated protein GPP34 PF05719.11 KUM58148.1 - 7.8e-66 222.0 0.1 1e-65 221.6 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) ADH_zinc_N_2 PF13602.6 KUM58149.1 - 7.9e-05 23.7 0.0 0.00018 22.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fer4 PF00037.27 KUM58150.1 - 3.8e-14 51.8 15.9 3.5e-08 32.9 4.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KUM58150.1 - 4.7e-13 49.5 10.5 7.3e-13 48.9 10.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KUM58150.1 - 1.3e-10 42.0 8.3 1.5e-05 25.8 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KUM58150.1 - 2.2e-10 40.5 21.8 3.8e-07 30.1 12.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KUM58150.1 - 7.8e-10 38.8 21.1 5.1e-08 32.9 10.8 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KUM58150.1 - 1.4e-09 37.9 5.9 0.00011 22.2 0.4 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KUM58150.1 - 8.4e-09 35.8 2.8 0.0002 21.8 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KUM58150.1 - 1.6e-06 27.9 17.5 0.00038 20.4 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KUM58150.1 - 4.8e-06 26.3 12.5 0.01 15.9 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KUM58150.1 - 1.5e-05 25.2 11.0 0.00028 21.1 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KUM58150.1 - 8.8e-05 23.0 11.9 0.016 15.7 1.9 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KUM58150.1 - 0.0095 16.1 5.4 0.69 10.2 0.2 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 KUM58150.1 - 0.037 14.2 8.9 1.1 9.4 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KUM58150.1 - 0.042 14.4 15.3 0.71 10.5 4.3 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KUM58150.1 - 0.064 14.2 15.7 0.11 13.4 3.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 KUM58150.1 - 0.093 12.9 5.9 0.38 10.9 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 KUM58150.1 - 0.25 12.2 11.5 1.9 9.4 1.7 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain DUF4451 PF14616.6 KUM58150.1 - 0.82 9.9 4.2 4.9 7.4 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) PP-binding PF00550.25 KUM58151.1 - 4.2e-10 39.8 0.1 5.6e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KUM58151.1 - 0.00016 21.9 0.1 0.00019 21.6 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF2183 PF09949.9 KUM58152.1 - 2.8e-34 117.4 0.0 6.5e-34 116.2 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) His_Phos_1 PF00300.22 KUM58153.1 - 3.8e-37 127.9 0.1 5e-37 127.5 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Acetyltransf_3 PF13302.7 KUM58154.1 - 8.8e-35 120.4 0.0 1.1e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM58154.1 - 0.00017 21.8 0.0 0.0021 18.3 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family But2 PF09792.9 KUM58155.1 - 2.1e-53 180.5 0.9 4.1e-53 179.6 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF2568 PF10823.8 KUM58156.1 - 0.12 12.7 9.8 0.055 13.7 4.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2568) PAP2 PF01569.21 KUM58157.1 - 1.1e-28 99.7 1.4 1.7e-28 99.1 0.3 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KUM58157.1 - 6.7 6.4 8.4 0.56 9.9 2.7 2.1 2 1 0 2 2 2 0 PAP2 superfamily Fungal_trans PF04082.18 KUM58158.1 - 4.3e-14 52.2 0.0 6.3e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.18 KUM58159.1 - 1.1e-59 201.7 0.0 1.4e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Cupin_2 PF07883.11 KUM58160.1 - 3.8e-18 65.0 0.1 3.6e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KUM58160.1 - 0.0047 16.6 0.0 0.79 9.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) CENP-C_C PF11699.8 KUM58160.1 - 0.0066 16.6 0.0 0.026 14.7 0.0 1.8 2 0 0 2 2 2 1 Mif2/CENP-C like AraC_binding PF02311.19 KUM58160.1 - 0.0084 16.0 0.6 3.1 7.7 0.0 2.7 2 1 1 3 3 3 2 AraC-like ligand binding domain DUF3830 PF12903.7 KUM58161.1 - 1.1e-28 99.7 0.0 1.2e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3830) Amidohydro_1 PF01979.20 KUM58162.1 - 1.4e-25 90.3 0.0 2e-24 86.5 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KUM58162.1 - 4.6e-15 56.1 0.1 4.1e-06 26.5 0.6 2.5 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.20 KUM58162.1 - 0.0009 19.6 0.2 0.0021 18.4 0.2 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain SERTA PF06031.13 KUM58163.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 SERTA motif Fungal_trans PF04082.18 KUM58165.1 - 4e-20 72.0 0.5 7.9e-20 71.0 0.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain TauD PF02668.16 KUM58166.1 - 1.5e-47 162.6 0.4 1.9e-47 162.3 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DPRP PF04244.13 KUM58166.1 - 0.038 13.9 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein S-AdoMet_synt_C PF02773.16 KUM58167.1 - 1e-66 223.2 0.5 1.3e-65 219.6 0.1 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KUM58167.1 - 4.9e-44 149.4 0.0 9.5e-44 148.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KUM58167.1 - 6.2e-44 148.7 0.6 1.2e-43 147.8 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Lactamase_B_3 PF13483.6 KUM58167.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain AA_permease PF00324.21 KUM58168.1 - 2.8e-96 323.0 45.4 7e-55 186.5 28.1 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KUM58168.1 - 1.3e-22 80.2 43.6 1.5e-14 53.7 26.9 2.0 1 1 1 2 2 2 2 Amino acid permease DUF2070 PF09843.9 KUM58169.1 - 0.074 11.3 10.1 0.095 11.0 10.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MIG-14_Wnt-bd PF06664.12 KUM58169.1 - 0.12 11.5 20.8 0.21 10.8 13.6 2.8 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion DUF420 PF04238.12 KUM58169.1 - 0.16 12.2 7.3 0.14 12.4 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF420) DUF1772 PF08592.11 KUM58169.1 - 0.17 12.2 5.1 3.1 8.1 1.1 3.0 2 2 0 3 3 3 0 Domain of unknown function (DUF1772) SLD3 PF08639.10 KUM58170.1 - 7.1e-167 556.4 9.7 7.1e-167 556.4 9.7 1.9 2 0 0 2 2 2 1 DNA replication regulator SLD3 DHDPS PF00701.22 KUM58171.1 - 3.1e-27 95.0 0.0 1.3e-26 93.0 0.0 1.9 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family ATP_bind_1 PF03029.17 KUM58172.1 - 1.6e-76 257.3 0.2 1.8e-76 257.1 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 KUM58172.1 - 0.00039 20.5 0.0 0.0011 19.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KUM58172.1 - 0.00074 18.7 0.1 0.0022 17.1 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 KUM58172.1 - 0.0022 18.4 0.0 0.0073 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KUM58172.1 - 0.004 17.3 0.0 0.008 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KUM58172.1 - 0.0049 17.2 1.1 0.062 13.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain CLP1_P PF16575.5 KUM58172.1 - 0.0058 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 KUM58172.1 - 0.007 15.6 0.3 0.049 12.8 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 KUM58172.1 - 0.0075 16.7 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KUM58172.1 - 0.0082 16.1 0.1 0.26 11.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KUM58172.1 - 0.0085 15.6 0.2 3.5 7.1 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RNA_helicase PF00910.22 KUM58172.1 - 0.01 16.2 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 KUM58172.1 - 0.014 14.7 0.0 0.035 13.3 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain TsaE PF02367.17 KUM58172.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KUM58172.1 - 0.018 14.8 0.1 0.069 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KUM58172.1 - 0.023 14.2 0.0 0.05 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KUM58172.1 - 0.024 15.1 0.0 0.073 13.6 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 KUM58172.1 - 0.025 14.8 0.0 0.067 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KUM58172.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KUM58172.1 - 0.029 14.9 0.0 0.062 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KUM58172.1 - 0.03 14.0 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ArsA_ATPase PF02374.15 KUM58172.1 - 0.034 13.3 0.2 0.086 12.0 0.0 1.6 2 0 0 2 2 2 0 Anion-transporting ATPase RuvB_N PF05496.12 KUM58172.1 - 0.037 13.8 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_31 PF13614.6 KUM58172.1 - 0.04 13.8 0.0 4.3 7.2 0.0 2.4 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 KUM58172.1 - 0.048 13.2 0.1 0.98 9.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KUM58172.1 - 0.049 13.4 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KUM58172.1 - 0.061 12.6 0.0 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Septin MMR_HSR1 PF01926.23 KUM58172.1 - 0.061 13.4 0.0 0.21 11.7 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 KUM58172.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KUM58172.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 KUM58172.1 - 0.096 12.3 0.0 0.51 10.0 0.0 2.1 2 1 0 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.12 KUM58172.1 - 0.096 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 KUM58172.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KUM58172.1 - 0.11 11.8 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 KUM58172.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein CbiA PF01656.23 KUM58172.1 - 0.19 11.8 0.0 0.29 11.2 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Apq12 PF12716.7 KUM58173.1 - 1.4e-18 66.5 12.9 2.3e-18 65.9 12.9 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis DUF5345 PF17280.2 KUM58173.1 - 1.8 8.6 6.2 3.2 7.8 6.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5345) PI3_PI4_kinase PF00454.27 KUM58175.1 - 1.8e-43 149.2 0.0 2.5e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase MutL_C PF08676.11 KUM58176.1 - 2e-24 86.0 0.0 5.1e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KUM58176.1 - 2.3e-18 66.0 0.0 2.2e-17 62.8 0.0 2.7 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KUM58176.1 - 4.3e-11 42.8 0.0 1.5e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KUM58176.1 - 2.1e-06 28.2 0.1 1.3e-05 25.7 0.0 2.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MafB PF06255.13 KUM58176.1 - 0.13 11.7 0.7 0.22 10.9 0.7 1.3 1 0 0 1 1 1 0 Neisseria toxin MafB CDC45 PF02724.14 KUM58176.1 - 9.1 4.4 12.2 4.3 5.5 9.5 1.7 2 0 0 2 2 2 0 CDC45-like protein bZIP_1 PF00170.21 KUM58177.1 - 5.8e-06 26.3 0.5 1.4e-05 25.1 0.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.13 KUM58177.1 - 0.076 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF2034 PF10356.9 KUM58178.1 - 4.1e-42 143.7 0.0 3.3e-26 91.9 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KUM58178.1 - 3.7e-07 30.2 0.0 7.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease DUF1707 PF08044.11 KUM58178.1 - 0.24 11.5 2.1 0.91 9.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Med21 PF11221.8 KUM58179.1 - 7.6e-59 198.1 2.9 5.1e-58 195.4 2.9 1.8 1 1 0 1 1 1 1 Subunit 21 of Mediator complex APG6_N PF17675.1 KUM58179.1 - 0.014 15.9 0.7 0.057 13.9 1.2 1.6 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4455 PF14643.6 KUM58179.1 - 0.02 13.6 0.2 0.029 13.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) DUF4515 PF14988.6 KUM58179.1 - 0.025 14.4 0.6 0.041 13.7 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Med9 PF07544.13 KUM58179.1 - 0.027 14.6 0.8 0.13 12.4 0.8 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TPR_16 PF13432.6 KUM58179.1 - 0.044 14.4 0.0 0.081 13.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat SlyX PF04102.12 KUM58179.1 - 0.082 13.5 0.3 9.5 6.9 0.1 3.1 3 0 0 3 3 3 0 SlyX adh_short PF00106.25 KUM58180.1 - 8.9e-38 129.7 0.1 1.2e-37 129.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM58180.1 - 2.9e-26 92.5 0.2 3.8e-26 92.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KUM58180.1 - 6.7e-06 25.7 0.0 1.6e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KUM58180.1 - 1e-05 25.5 0.1 1.7e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM58180.1 - 0.0022 17.5 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KUM58180.1 - 0.12 11.9 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family SNF2_N PF00176.23 KUM58181.1 - 1.8e-63 214.4 0.0 2.9e-63 213.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KUM58181.1 - 2.6e-08 34.2 0.0 6.9e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KUM58181.1 - 0.00012 21.9 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KUM58181.1 - 0.00058 19.9 0.1 0.0021 18.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HIRAN PF08797.11 KUM58181.1 - 0.029 14.3 0.0 0.079 12.9 0.0 1.7 1 0 0 1 1 1 0 HIRAN domain Anti-TRAP PF15777.5 KUM58181.1 - 0.17 11.9 0.4 0.43 10.6 0.4 1.7 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-RING_5 PF14634.6 KUM58181.1 - 0.37 10.8 5.4 0.7 9.9 5.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KUM58181.1 - 0.53 10.7 8.3 1.2 9.5 8.3 1.7 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 KUM58181.1 - 0.62 10.0 6.7 1.6 8.7 6.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Aminotran_5 PF00266.19 KUM58182.1 - 2.8e-20 72.6 0.0 5e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KUM58182.1 - 1.4e-05 24.4 0.0 2.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KUM58182.1 - 0.032 13.5 0.1 0.55 9.5 0.1 2.2 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pro_CA PF00484.19 KUM58183.1 - 2e-06 28.2 0.3 1.6e-05 25.2 0.3 2.0 1 1 0 1 1 1 1 Carbonic anhydrase LEH PF07858.12 KUM58183.1 - 0.071 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain Fis1_TPR_C PF14853.6 KUM58184.1 - 8.1e-25 86.6 0.4 1.3e-24 86.0 0.4 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KUM58184.1 - 2.5e-16 59.1 0.1 4.1e-16 58.3 0.1 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KUM58184.1 - 0.012 15.7 1.4 0.012 15.7 1.4 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Spc24 PF08286.11 KUM58185.1 - 1.8e-36 124.6 1.5 4e-35 120.2 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.20 KUM58185.1 - 0.012 15.5 2.1 3.1 7.8 1.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit CLZ PF16526.5 KUM58185.1 - 0.014 15.8 6.7 1.5 9.2 0.3 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Streptin-Immun PF11083.8 KUM58185.1 - 0.071 13.5 0.2 0.83 10.1 0.0 2.1 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein APG6_N PF17675.1 KUM58185.1 - 0.1 13.1 10.6 0.15 12.6 10.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4795 PF16043.5 KUM58185.1 - 0.13 11.8 4.4 0.49 10.0 4.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) SlyX PF04102.12 KUM58185.1 - 0.32 11.7 5.8 1.1 10.0 0.8 2.4 2 0 0 2 2 2 0 SlyX TPR_MLP1_2 PF07926.12 KUM58185.1 - 0.52 10.4 11.3 0.29 11.2 2.9 2.1 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DMPK_coil PF08826.10 KUM58185.1 - 0.8 9.9 9.7 1.3 9.2 1.0 2.2 2 0 0 2 2 2 0 DMPK coiled coil domain like Phage_GPO PF05929.11 KUM58185.1 - 1.1 8.8 5.1 4.2 6.9 5.1 1.8 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase FlaC_arch PF05377.11 KUM58185.1 - 2.4 8.6 6.1 19 5.8 0.1 2.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 KUM58185.1 - 7 6.9 6.7 8 6.7 1.0 2.2 2 0 0 2 2 2 0 Haemolysin XhlA GCN5L1 PF06320.13 KUM58186.1 - 1.3e-21 76.8 2.8 2.3e-21 76.1 2.8 1.3 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Nodulin-like PF06813.13 KUM58187.1 - 1.2e-23 83.9 1.7 2.5e-23 82.9 1.7 1.5 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 KUM58187.1 - 1.6e-14 53.7 40.7 3.1e-13 49.4 15.8 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily GATA PF00320.27 KUM58188.1 - 1.8e-15 56.3 2.6 3e-15 55.5 2.6 1.4 1 0 0 1 1 1 1 GATA zinc finger Pox_A_type_inc PF04508.12 KUM58188.1 - 3.1e-05 23.6 2.9 0.012 15.4 0.8 3.4 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat CENP-F_N PF10481.9 KUM58188.1 - 0.011 15.4 2.3 0.077 12.6 0.1 2.1 1 1 0 2 2 2 0 Cenp-F N-terminal domain TF_Zn_Ribbon PF08271.12 KUM58188.1 - 0.013 15.0 0.6 0.027 14.0 0.6 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DivIVA PF05103.13 KUM58188.1 - 0.085 12.9 1.3 0.75 9.9 1.3 2.0 1 1 0 1 1 1 0 DivIVA protein CLZ PF16526.5 KUM58188.1 - 0.19 12.1 4.9 4 7.9 1.5 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-F_leu_zip PF10473.9 KUM58188.1 - 0.19 11.7 4.9 6.8 6.7 1.7 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.15 KUM58188.1 - 1.3 9.2 8.5 5.2 7.2 0.1 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Serinc PF03348.15 KUM58189.1 - 1.1e-160 535.3 14.4 1.3e-160 535.1 14.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) AMP-binding PF00501.28 KUM58190.1 - 4.8e-137 457.0 0.0 5.1e-73 246.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KUM58190.1 - 6.5e-79 265.7 0.0 6.8e-44 150.3 0.0 3.2 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.25 KUM58190.1 - 7e-23 80.8 0.6 1.4e-10 41.3 0.1 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM58190.1 - 6.2e-07 30.3 0.0 0.0012 19.7 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KUM58190.1 - 2.1 7.1 4.3 29 3.4 0.0 3.5 4 0 0 4 4 4 0 GH3 auxin-responsive promoter DUF1700 PF08006.11 KUM58191.1 - 0.43 10.1 12.5 0.74 9.3 12.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) DUF4834 PF16118.5 KUM58191.1 - 1.2 10.1 4.4 1.4 9.9 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) HemY_N PF07219.13 KUM58191.1 - 1.4 9.1 5.4 1.7 8.9 5.4 1.2 1 0 0 1 1 1 0 HemY protein N-terminus GP41 PF00517.17 KUM58191.1 - 2 8.3 7.3 2 8.3 7.3 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Pex24p PF06398.11 KUM58191.1 - 2.7 6.9 6.9 2.6 7.0 6.9 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Baculo_F PF12259.8 KUM58191.1 - 4.9 5.6 5.9 5.2 5.5 5.9 1.0 1 0 0 1 1 1 0 Baculovirus F protein Asn_synthase PF00733.21 KUM58193.1 - 2.1e-67 228.3 0.0 2.9e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KUM58193.1 - 9.5e-36 122.4 0.0 1.9e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KUM58193.1 - 1.6e-29 102.8 0.0 3.4e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KUM58193.1 - 0.00039 19.9 0.0 0.00072 19.1 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein tRNA_Me_trans PF03054.16 KUM58193.1 - 0.057 12.2 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Ras PF00071.22 KUM58194.1 - 5.9e-40 136.5 0.0 7.9e-38 129.6 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KUM58194.1 - 9.9e-32 109.7 0.0 1.4e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM58194.1 - 9.2e-12 44.8 0.0 1.8e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KUM58194.1 - 5.6e-05 23.2 0.0 8.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KUM58194.1 - 0.00051 19.5 0.0 0.00068 19.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KUM58194.1 - 0.0011 19.4 0.0 0.0023 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 KUM58194.1 - 0.0033 16.8 0.0 0.0042 16.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KUM58194.1 - 0.074 13.3 0.1 0.2 11.9 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KUM58194.1 - 0.082 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KUM58194.1 - 0.091 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Herpes_capsid PF06112.11 KUM58194.1 - 0.73 9.9 4.7 1.3 9.1 4.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein GATase PF00117.28 KUM58195.1 - 7.3e-11 42.2 0.0 9.5e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KUM58195.1 - 0.088 12.6 0.1 0.21 11.3 0.1 1.7 1 1 0 1 1 1 0 Peptidase C26 FAD_binding_4 PF01565.23 KUM58196.1 - 2.7e-19 69.3 2.5 4.9e-19 68.4 1.8 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KUM58196.1 - 7.4e-07 29.2 0.1 1.4e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 KUM58197.1 - 2.7e-19 69.4 0.1 2.2e-13 50.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM58197.1 - 4.2e-08 33.1 0.0 0.00017 21.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KUM58197.1 - 2.5e-05 24.2 0.0 4.3e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KUM58197.1 - 0.0028 17.6 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM58197.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.24 KUM58198.1 - 2.9e-103 346.2 24.6 3.4e-103 346.0 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM58198.1 - 1.3e-23 83.5 35.7 3.7e-14 52.4 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PNP_UDP_1 PF01048.20 KUM58200.1 - 6.1e-16 58.4 0.0 1.4e-15 57.2 0.0 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily AKNA PF12443.8 KUM58200.1 - 0.0067 17.1 0.5 0.049 14.3 0.3 2.6 1 1 1 2 2 2 1 AT-hook-containing transcription factor Herpes_UL42 PF02282.16 KUM58200.1 - 0.28 11.0 1.0 2.2 8.1 0.1 2.3 2 0 0 2 2 2 0 DNA polymerase processivity factor (UL42) CDH-cyt PF16010.5 KUM58201.1 - 1.9e-68 229.7 5.5 2.4e-68 229.4 5.5 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KUM58201.1 - 0.0048 17.1 0.1 0.01 16.0 0.1 1.6 1 0 0 1 1 1 1 DOMON domain AMP-binding PF00501.28 KUM58202.1 - 3.9e-204 678.0 0.0 3.3e-74 250.0 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KUM58202.1 - 1.6e-179 597.3 0.0 1.6e-46 158.9 0.0 6.0 5 1 0 5 5 5 5 Condensation domain PP-binding PF00550.25 KUM58202.1 - 1.3e-40 137.6 0.1 3.4e-13 49.7 0.0 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM58202.1 - 0.0015 19.5 0.0 4.9 8.2 0.0 3.2 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Myb_DNA-bind_7 PF15963.5 KUM58203.1 - 7.4e-05 22.6 0.6 0.00027 20.8 0.6 2.0 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KUM58203.1 - 0.021 15.0 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-C2H2_2 PF12756.7 KUM58203.1 - 0.078 13.3 4.7 0.049 14.0 2.4 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Endonuclease_7 PF02945.15 KUM58203.1 - 0.12 12.4 4.4 8.2 6.4 0.4 2.9 2 1 0 2 2 2 0 Recombination endonuclease VII DDHD PF02862.17 KUM58203.1 - 1.7 8.8 6.9 7.8 6.6 4.1 2.6 2 0 0 2 2 2 0 DDHD domain zf-C2H2 PF00096.26 KUM58203.1 - 3.7 8.2 8.9 28 5.4 0.4 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type Gly_transf_sug PF04488.15 KUM58204.1 - 1.7e-09 38.2 0.0 3.2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KUM58204.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein ORC6 PF05460.13 KUM58204.1 - 1.5 8.0 7.2 3.6 6.8 7.2 1.6 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ABC_tran PF00005.27 KUM58205.1 - 1.3e-34 119.6 0.0 2.4e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KUM58205.1 - 2.8e-26 92.8 6.4 4e-26 92.3 6.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 KUM58205.1 - 3.4e-07 30.8 0.0 7.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KUM58205.1 - 1.4e-05 24.7 0.5 0.0068 15.9 0.0 2.7 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KUM58205.1 - 0.00031 21.0 0.1 0.003 17.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KUM58205.1 - 0.0012 18.7 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 KUM58205.1 - 0.0034 16.2 0.1 0.012 14.4 0.0 1.8 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA PF00004.29 KUM58205.1 - 0.0073 16.7 0.0 1.3 9.5 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KUM58205.1 - 0.01 15.9 0.0 0.059 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KUM58205.1 - 0.013 15.2 0.1 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KUM58205.1 - 0.045 13.3 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KUM58205.1 - 0.05 13.4 0.1 0.21 11.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 KUM58205.1 - 0.055 12.6 0.1 0.44 9.7 0.0 2.3 3 0 0 3 3 3 0 NB-ARC domain AAA_28 PF13521.6 KUM58205.1 - 0.065 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KUM58205.1 - 0.072 13.2 0.1 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KUM58205.1 - 0.076 12.9 0.1 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_15 PF13175.6 KUM58205.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KUM58205.1 - 0.17 12.4 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 KUM58206.1 - 1.8e-34 119.6 12.1 1.8e-34 119.6 12.1 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 KUM58206.1 - 1.9e-30 106.1 0.0 4e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KUM58206.1 - 2.5e-07 30.4 1.1 4.9e-05 22.9 0.3 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KUM58206.1 - 0.00011 21.9 0.1 0.00025 20.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KUM58206.1 - 0.00015 22.0 0.1 0.0016 18.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KUM58206.1 - 0.0012 18.7 0.0 0.0034 17.3 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KUM58206.1 - 0.01 16.4 0.0 0.019 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KUM58206.1 - 0.013 15.2 0.2 0.097 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KUM58206.1 - 0.013 14.6 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.6 KUM58206.1 - 0.03 14.7 0.0 0.086 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.6 KUM58206.1 - 0.041 13.6 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KUM58206.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3987 PF13148.6 KUM58206.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TniB PF05621.11 KUM58206.1 - 0.14 11.6 0.0 0.58 9.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA PF00004.29 KUM58206.1 - 0.15 12.5 0.0 22 5.5 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Phage_lysozyme PF00959.19 KUM58207.1 - 4.8e-12 46.3 0.0 6.6e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme PNP_UDP_1 PF01048.20 KUM58208.1 - 0.00026 20.3 1.2 0.00049 19.4 1.2 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily CDT1_C PF16679.5 KUM58209.1 - 1.4e-21 76.7 0.1 2.2e-20 72.9 0.0 2.4 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain Lentiviral_Tat PF02998.14 KUM58209.1 - 0.094 12.8 0.1 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Lentiviral Tat protein Phasin PF05597.11 KUM58210.1 - 0.011 15.7 2.1 0.015 15.3 1.9 1.3 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Apolipoprotein PF01442.18 KUM58210.1 - 0.012 15.5 5.3 0.021 14.7 5.3 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ZnuA PF01297.17 KUM58210.1 - 0.016 14.6 0.6 0.024 14.0 0.6 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF743 PF05332.11 KUM58210.1 - 0.022 14.8 0.9 0.029 14.4 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF743) DUF883 PF05957.13 KUM58210.1 - 0.022 15.3 5.9 0.033 14.8 3.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2508 PF10704.9 KUM58210.1 - 0.1 12.8 1.4 0.17 12.0 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) ISG65-75 PF11727.8 KUM58210.1 - 0.14 11.4 3.7 0.17 11.1 3.7 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Prominin PF05478.11 KUM58210.1 - 0.31 9.0 0.0 0.33 8.9 0.0 1.0 1 0 0 1 1 1 0 Prominin V-ATPase_G_2 PF16999.5 KUM58210.1 - 2.5 8.6 9.2 1.7 9.1 6.9 1.8 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 KUM58210.1 - 6.6 6.8 10.9 4.2 7.5 9.0 1.5 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) zf-C2H2 PF00096.26 KUM58211.1 - 2e-05 24.8 14.9 0.0056 17.1 2.3 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KUM58211.1 - 0.00027 21.2 3.8 0.00027 21.2 3.8 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KUM58211.1 - 0.00095 19.8 11.9 0.071 14.0 2.9 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger TylF PF05711.11 KUM58211.1 - 0.031 13.5 0.0 0.33 10.2 0.0 2.0 2 0 0 2 2 2 0 Macrocin-O-methyltransferase (TylF) zf-H2C2_5 PF13909.6 KUM58211.1 - 1.3 8.9 5.6 2.4 8.0 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain COG5 PF10392.9 KUM58212.1 - 2e-40 138.0 0.6 6.6e-40 136.3 0.6 1.9 1 0 0 1 1 1 1 Golgi transport complex subunit 5 RTBV_P12 PF06361.11 KUM58212.1 - 0.077 13.4 0.0 0.54 10.7 0.0 2.3 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein Aldolase_II PF00596.21 KUM58215.1 - 1.3e-47 162.1 0.1 1.7e-47 161.8 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain tRNA-synt_2 PF00152.20 KUM58216.1 - 4e-87 292.2 0.0 5.9e-87 291.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KUM58216.1 - 9.5e-08 31.9 0.0 1.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SERTA PF06031.13 KUM58217.1 - 0.029 14.0 0.3 0.066 12.9 0.3 1.6 1 0 0 1 1 1 0 SERTA motif Aft1_HRR PF11787.8 KUM58219.1 - 1.7 9.9 9.0 3.6 8.8 1.6 2.4 2 0 0 2 2 2 0 Aft1 HRR domain Ecl1 PF12855.7 KUM58220.1 - 8e-24 85.7 18.2 1e-23 85.4 18.2 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins SmpA_OmlA PF04355.13 KUM58220.1 - 0.13 12.0 0.0 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 SmpA / OmlA family Iwr1 PF08574.10 KUM58221.1 - 1.4e-20 74.1 12.6 1.4e-20 74.1 12.6 3.0 3 0 0 3 3 3 1 Transcription factor Iwr1 DUF4733 PF15878.5 KUM58221.1 - 0.03 14.8 0.5 0.03 14.8 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4733) RRM_1 PF00076.22 KUM58222.1 - 2.2e-37 126.7 0.0 1.6e-11 43.9 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KUM58222.1 - 1.6e-13 50.3 0.0 0.0012 18.6 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM PF10378.9 KUM58222.1 - 4e-09 36.1 0.9 2.5e-08 33.5 0.9 2.5 1 0 0 1 1 1 1 Putative RRM domain RRM_3 PF08777.11 KUM58222.1 - 0.00014 21.9 0.0 0.38 10.8 0.0 3.0 3 0 0 3 3 3 2 RNA binding motif DUF4523 PF15023.6 KUM58222.1 - 0.00033 20.5 0.0 0.48 10.2 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_Rrp7 PF17799.1 KUM58222.1 - 0.0019 18.0 0.0 1.4 8.7 0.0 4.0 2 1 2 4 4 4 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KUM58222.1 - 0.0029 17.7 0.0 4.1 7.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif MT-A70 PF05063.14 KUM58223.1 - 5.2e-22 78.6 0.1 1.3e-15 57.7 0.0 2.9 2 1 0 2 2 2 2 MT-A70 PUF PF00806.19 KUM58224.1 - 1.4e-27 93.8 0.0 3.9e-05 23.1 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 KUM58224.1 - 3.3e-10 39.6 0.0 8e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EAV_GP5 PF15981.5 KUM58225.1 - 0.096 13.1 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Envelope glycoprotein GP 5 of equine arteritis virus YL1 PF05764.13 KUM58226.1 - 1.3e-56 192.4 24.1 1.3e-56 192.4 24.1 2.7 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 KUM58226.1 - 4e-11 42.5 0.7 4e-11 42.5 0.7 1.9 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Fungal_trans PF04082.18 KUM58227.1 - 1.7e-09 37.2 0.3 2.3e-09 36.7 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Stealth_CR4 PF17103.5 KUM58227.1 - 0.015 15.2 0.1 0.037 13.9 0.1 1.6 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 Fungal_trans PF04082.18 KUM58229.1 - 9.4e-08 31.4 4.6 7.4e-07 28.5 4.6 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.23 KUM58230.1 - 5.9e-58 196.7 0.0 7.6e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KUM58230.1 - 4.5e-19 68.6 7.0 8e-19 67.8 4.1 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KUM58230.1 - 6.7e-07 29.2 0.5 3.2e-06 27.0 0.5 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 KUM58230.1 - 0.014 16.1 0.4 0.032 14.9 0.4 1.6 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase MR_MLE_C PF13378.6 KUM58231.1 - 3.7e-50 170.5 0.1 5.5e-50 170.0 0.1 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KUM58231.1 - 0.00024 21.3 0.0 0.0005 20.3 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KUM58231.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus NACHT PF05729.12 KUM58232.1 - 4.6e-11 42.9 0.7 2e-10 40.9 0.0 2.5 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 KUM58232.1 - 7.5e-06 26.4 1.1 4.8e-05 23.8 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KUM58232.1 - 0.003 17.8 3.6 0.015 15.5 0.0 3.6 3 1 0 3 3 3 1 AAA domain CRIC_ras_sig PF10534.9 KUM58232.1 - 0.019 15.1 1.5 0.076 13.2 0.1 2.6 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras ABC_tran PF00005.27 KUM58232.1 - 0.051 14.1 1.2 0.18 12.3 0.0 2.3 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KUM58232.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SesA PF17107.5 KUM58232.1 - 0.15 12.2 3.4 0.91 9.7 0.1 2.7 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF87 PF01935.17 KUM58232.1 - 0.69 10.0 4.3 1.4 9.0 0.0 2.8 2 1 1 3 3 3 0 Helicase HerA, central domain NifT PF06988.11 KUM58234.1 - 0.19 11.5 0.5 0.84 9.5 0.3 1.9 1 1 1 2 2 2 0 NifT/FixU protein Epimerase PF01370.21 KUM58235.1 - 2.5e-16 59.9 0.0 4.1e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KUM58235.1 - 1.6e-13 50.3 0.0 2.8e-13 49.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KUM58235.1 - 3.6e-12 46.5 0.0 4.9e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KUM58235.1 - 1.1e-08 34.6 0.0 0.0033 16.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KUM58235.1 - 6.7e-08 32.3 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KUM58235.1 - 1e-06 28.5 0.0 1.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KUM58235.1 - 1.8e-05 24.3 0.2 6.3e-05 22.5 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM58235.1 - 2.6e-05 24.2 0.0 5.4e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KUM58235.1 - 0.00052 19.2 0.0 0.00082 18.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KUM58235.1 - 0.096 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Sugar_tr PF00083.24 KUM58236.1 - 9.1e-109 364.3 13.8 1.1e-108 364.1 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM58236.1 - 3.3e-25 88.8 7.7 3.3e-25 88.8 7.7 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KUM58236.1 - 0.00036 19.5 0.1 0.022 13.6 0.0 2.6 2 2 1 3 3 3 1 MFS_1 like family TRI12 PF06609.13 KUM58236.1 - 0.0039 15.7 5.2 0.0047 15.4 0.2 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SNARE_assoc PF09335.11 KUM58236.1 - 0.079 13.5 0.3 0.079 13.5 0.3 3.5 4 1 0 4 4 4 0 SNARE associated Golgi protein DUF3176 PF11374.8 KUM58237.1 - 2.3e-36 124.2 1.0 2.3e-36 124.2 1.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Tim17 PF02466.19 KUM58238.1 - 3.8e-31 107.7 7.5 4.7e-31 107.5 7.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.6 KUM58238.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal CorA PF01544.18 KUM58239.1 - 2e-14 53.6 3.3 4e-14 52.6 3.3 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein adh_short_C2 PF13561.6 KUM58240.1 - 4.6e-30 104.9 0.3 6.1e-30 104.5 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM58240.1 - 1e-20 74.0 0.1 1.3e-20 73.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM58240.1 - 0.00015 21.7 0.2 0.00036 20.5 0.1 1.5 2 0 0 2 2 2 1 KR domain DELLA PF12041.8 KUM58240.1 - 0.0044 16.9 0.1 0.0088 15.9 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator DELLA protein N terminal Eno-Rase_NADH_b PF12242.8 KUM58240.1 - 0.0063 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Helicase_RecD PF05127.14 KUM58240.1 - 0.01 15.7 0.2 0.26 11.1 0.2 2.1 1 1 0 1 1 1 1 Helicase THF_DHG_CYH_C PF02882.19 KUM58240.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.26 KUM58240.1 - 0.093 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Peptidase_S9 PF00326.21 KUM58243.1 - 0.00061 19.3 1.1 0.0008 18.9 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KUM58243.1 - 0.00075 20.2 2.9 0.00075 20.2 2.9 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM58243.1 - 0.0023 17.6 0.1 0.031 13.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KUM58243.1 - 0.023 14.2 0.0 0.057 13.0 0.0 1.7 1 0 0 1 1 1 0 Dienelactone hydrolase family Esterase PF00756.20 KUM58243.1 - 0.026 14.2 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative esterase ADH_zinc_N PF00107.26 KUM58244.1 - 5.1e-06 26.5 0.0 8.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM58244.1 - 0.11 12.4 0.1 0.3 11.0 0.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Benyvirus_P25 PF05744.11 KUM58245.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Benyvirus P25/P26 protein FAD_binding_4 PF01565.23 KUM58246.1 - 4.6e-22 78.2 1.9 8.2e-22 77.4 1.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KUM58246.1 - 7.2e-09 35.6 0.3 1.4e-08 34.7 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like NAD_binding_8 PF13450.6 KUM58248.1 - 1.1e-09 38.4 0.0 2.6e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KUM58248.1 - 1.7e-08 34.2 0.0 3.9e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KUM58248.1 - 0.00012 21.5 0.0 0.003 16.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM58248.1 - 0.0012 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KUM58248.1 - 0.004 16.4 0.0 0.0077 15.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KUM58248.1 - 0.024 14.0 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KUM58248.1 - 0.024 13.9 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KUM58248.1 - 0.024 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KUM58248.1 - 0.029 13.1 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 KUM58248.1 - 0.042 13.9 0.0 0.16 12.0 0.0 2.0 1 1 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KUM58248.1 - 0.07 13.4 0.1 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.12 KUM58248.1 - 0.12 11.3 0.1 0.22 10.5 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KUM58248.1 - 0.13 11.3 0.1 0.23 10.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain p450 PF00067.22 KUM58249.1 - 6.2e-65 219.7 0.0 1.5e-64 218.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KUM58251.1 - 9.3e-27 93.9 0.1 1.2e-25 90.2 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 baeRF_family8 PF18851.1 KUM58251.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 8 DUF1746 PF08508.10 KUM58251.1 - 0.15 12.5 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1746) Methyltransf_23 PF13489.6 KUM58252.1 - 4.8e-10 39.5 0.0 7.2e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM58252.1 - 2.6e-09 37.7 0.0 8.6e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM58252.1 - 2.7e-09 37.7 0.0 5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM58252.1 - 6.6e-08 32.5 0.0 1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM58252.1 - 4.9e-07 30.3 0.0 1.4e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM58252.1 - 1.4e-05 24.6 0.0 2.5e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family NAS PF03059.16 KUM58252.1 - 0.028 13.8 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein CheR PF01739.18 KUM58252.1 - 0.046 13.2 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain AMP-binding PF00501.28 KUM58253.1 - 1.7e-72 244.4 0.0 4e-72 243.1 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KUM58253.1 - 4.4e-72 242.7 0.0 1.1e-71 241.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 KUM58253.1 - 8.5e-68 229.1 0.0 1.6e-67 228.2 0.0 1.4 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 KUM58253.1 - 7.6e-49 166.5 0.1 1.4e-48 165.7 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KUM58253.1 - 9.6e-49 165.7 0.3 2.1e-46 158.1 0.1 2.7 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KUM58253.1 - 1.3e-38 133.3 0.1 2.5e-38 132.4 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KUM58253.1 - 2.6e-36 125.1 0.0 1.6e-35 122.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 KUM58253.1 - 6e-29 100.5 0.0 1.8e-28 98.9 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KUM58253.1 - 2.6e-19 69.8 0.0 9.1e-19 68.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KUM58253.1 - 9.5e-19 67.8 0.0 2e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 KUM58253.1 - 1.3e-16 61.0 0.0 7.3e-16 58.6 0.0 2.4 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 KUM58253.1 - 2e-16 60.3 0.0 4.9e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM58253.1 - 8.2e-14 51.7 0.0 2e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KUM58253.1 - 1.1e-13 51.3 0.6 1.4e-05 25.3 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 KUM58253.1 - 1.3e-13 51.5 0.0 4.3e-13 49.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM58253.1 - 1.8e-13 50.9 0.0 5.4e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_10 PF13460.6 KUM58253.1 - 1.5e-10 41.3 0.0 4.4e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H-binding Ubie_methyltran PF01209.18 KUM58253.1 - 7.4e-09 35.3 0.0 1.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.19 KUM58253.1 - 1e-08 34.5 0.0 1.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KUM58253.1 - 2.3e-08 33.8 0.0 4e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KUM58253.1 - 4e-08 33.0 1.4 1.8e-06 27.6 0.1 3.3 2 1 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 KUM58253.1 - 4.6e-05 22.9 0.0 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 KUM58253.1 - 0.0004 20.0 0.0 0.001 18.7 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_16 PF10294.9 KUM58253.1 - 0.013 15.3 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase AMP-binding_C PF13193.6 KUM58253.1 - 0.013 16.5 0.0 0.11 13.4 0.0 2.6 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain MTS PF05175.14 KUM58253.1 - 0.017 14.7 0.0 0.054 13.0 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase small domain MFS_1 PF07690.16 KUM58254.1 - 0.89 8.4 5.6 1.5 7.7 5.5 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF521 PF04412.13 KUM58255.1 - 3.7e-137 457.3 0.0 1.1e-136 455.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF521) DUF126 PF01989.16 KUM58255.1 - 2.8e-31 107.1 0.0 6.2e-31 106.0 0.0 1.6 1 0 0 1 1 1 1 Aconitase X swivel domain MoaC PF01967.21 KUM58256.1 - 5.1e-47 159.4 0.3 8.2e-47 158.7 0.3 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KUM58256.1 - 5.8e-37 126.5 0.0 3e-36 124.2 0.0 2.0 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KUM58256.1 - 1.8e-20 74.0 0.0 3.9e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily p450 PF00067.22 KUM58257.1 - 1.8e-63 214.9 0.0 2.1e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.27 KUM58259.1 - 3.7e-25 89.0 3.3 2.3e-13 50.8 0.3 3.0 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KUM58259.1 - 4.7e-09 36.1 5.6 8.1e-09 35.4 5.6 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KUM58259.1 - 2e-06 27.9 0.0 0.05 13.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KUM58259.1 - 0.0066 16.5 0.5 0.034 14.2 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 KUM58259.1 - 0.0072 16.8 1.5 0.078 13.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 KUM58259.1 - 0.011 14.4 1.0 0.19 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.8 KUM58259.1 - 0.013 13.1 0.8 0.013 13.1 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) SMC_N PF02463.19 KUM58259.1 - 0.014 14.8 3.3 1.3 8.4 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KUM58259.1 - 0.096 12.4 0.4 0.29 10.9 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KUM58259.1 - 0.1 12.5 0.7 0.2 11.5 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase MobB PF03205.14 KUM58259.1 - 0.12 12.3 1.1 0.2 11.5 0.2 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TbpB_B_D PF01298.18 KUM58259.1 - 0.12 12.8 0.2 0.19 12.1 0.2 1.3 1 0 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B TORC_M PF12885.7 KUM58259.1 - 0.22 11.4 0.3 0.57 10.1 0.3 1.6 1 1 0 1 1 1 0 Transducer of regulated CREB activity middle domain AAA_33 PF13671.6 KUM58259.1 - 0.61 10.2 2.6 1.3 9.2 0.3 2.1 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 KUM58262.1 - 7e-69 231.7 0.1 1.4e-68 230.8 0.1 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KUM58262.1 - 0.0006 19.3 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KUM58262.1 - 0.0094 16.2 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KUM58262.1 - 0.011 15.8 0.0 0.029 14.4 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRPRB PF09439.10 KUM58262.1 - 0.012 15.1 0.0 0.029 13.8 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KUM58262.1 - 0.045 14.1 0.0 0.069 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 KUM58262.1 - 0.053 13.3 0.1 0.086 12.6 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 KUM58262.1 - 0.1 12.6 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Lactamase_B_4 PF13691.6 KUM58263.1 - 4.1e-25 87.2 0.1 8.8e-25 86.2 0.1 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KUM58263.1 - 1.7e-12 47.3 0.1 2.5e-10 40.2 0.1 2.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF2188 PF09954.9 KUM58263.1 - 0.072 13.3 1.4 0.55 10.4 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Lactamase_B PF00753.27 KUM58263.1 - 0.086 12.8 0.0 0.64 10.0 0.0 2.3 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily His_Phos_2 PF00328.22 KUM58264.1 - 4.9e-12 45.9 0.0 2.9e-10 40.1 0.0 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) bZIP_1 PF00170.21 KUM58265.1 - 4e-07 30.0 11.0 8e-07 29.1 11.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KUM58265.1 - 0.24 11.5 16.6 0.025 14.7 10.8 2.4 2 1 0 2 2 2 0 Basic region leucine zipper cobW PF02492.19 KUM58266.1 - 6.8e-48 162.6 5.4 6e-37 126.9 0.7 2.4 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KUM58266.1 - 2.9e-20 72.0 0.1 5.9e-16 58.2 0.0 2.8 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 KUM58266.1 - 0.0027 17.6 0.0 0.0057 16.6 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 KUM58266.1 - 0.0064 16.9 0.2 0.023 15.1 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 KUM58266.1 - 0.012 15.6 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 KUM58266.1 - 0.035 13.8 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 KUM58266.1 - 0.057 12.5 0.4 0.14 11.2 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.6 KUM58266.1 - 0.067 13.3 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KUM58266.1 - 0.12 12.6 0.3 0.39 11.0 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KUM58266.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SelP_N PF04592.14 KUM58266.1 - 0.33 10.3 6.8 7.7 5.8 3.7 2.5 2 0 0 2 2 2 0 Selenoprotein P, N terminal region CDC45 PF02724.14 KUM58266.1 - 0.99 7.6 11.8 0.25 9.6 0.6 2.2 2 0 0 2 2 2 0 CDC45-like protein DUF4637 PF15470.6 KUM58266.1 - 5.3 6.7 15.4 1.8 8.3 4.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) adh_short PF00106.25 KUM58267.1 - 1.2e-28 99.9 0.0 1.9e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM58267.1 - 4e-15 56.0 0.0 6.2e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM58267.1 - 0.0001 22.3 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KUM58267.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ABC_tran PF00005.27 KUM58268.1 - 6.9e-08 33.1 0.1 1.1e-07 32.4 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 KUM58268.1 - 0.00035 20.8 0.0 0.0008 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KUM58268.1 - 0.00069 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KUM58268.1 - 0.0022 17.9 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 KUM58268.1 - 0.0023 17.6 0.0 0.004 16.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KUM58268.1 - 0.006 17.1 0.6 0.02 15.4 0.1 2.0 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KUM58268.1 - 0.0071 16.4 0.0 0.024 14.7 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KUM58268.1 - 0.022 14.5 0.3 0.23 11.2 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.17 KUM58268.1 - 0.039 14.0 0.2 0.071 13.2 0.1 1.5 1 1 0 1 1 1 0 Helicase HerA, central domain AAA_33 PF13671.6 KUM58268.1 - 0.054 13.6 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KUM58268.1 - 0.058 13.8 0.0 0.091 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KUM58268.1 - 0.065 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KUM58268.1 - 0.068 13.6 0.0 0.17 12.2 0.0 1.7 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 KUM58268.1 - 0.079 13.2 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KUM58268.1 - 0.098 13.2 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KUM58268.1 - 0.1 12.7 0.1 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KUM58268.1 - 0.11 11.6 0.2 0.15 11.2 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 KUM58268.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 KUM58268.1 - 0.14 12.1 0.3 0.52 10.2 0.1 1.9 1 1 1 2 2 2 0 RsgA GTPase Ribul_P_3_epim PF00834.19 KUM58269.1 - 2.7e-59 199.9 0.0 4.2e-58 196.0 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 KUM58269.1 - 0.025 13.9 0.2 0.035 13.4 0.2 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG QRPTase_C PF01729.19 KUM58269.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain MFS_1 PF07690.16 KUM58270.1 - 6.4e-44 150.3 43.6 8.7e-44 149.9 43.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM58270.1 - 9.4e-12 44.5 18.5 9.4e-12 44.5 18.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KUM58270.1 - 2.5e-06 26.2 14.0 3.3e-06 25.8 14.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GST_N_2 PF13409.6 KUM58271.1 - 2.9e-12 46.7 0.0 9.9e-12 45.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KUM58271.1 - 2.1e-10 40.9 0.0 5.7e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KUM58271.1 - 3.3e-08 33.6 0.0 9.1e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KUM58271.1 - 5.2e-07 29.9 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KUM58271.1 - 0.00058 19.8 0.0 0.002 18.1 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KUM58271.1 - 0.0014 19.2 0.0 0.0028 18.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-BED PF02892.15 KUM58272.1 - 0.085 12.9 2.7 1.1 9.4 0.1 2.8 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.6 KUM58272.1 - 9.3 7.4 6.1 5 8.2 1.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger MFS_1 PF07690.16 KUM58273.1 - 1.3e-08 34.2 28.2 5.7e-07 28.8 28.2 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM58273.1 - 2.4e-05 22.9 6.5 3.1e-05 22.6 6.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Alpha-L-AF_C PF06964.12 KUM58274.1 - 4.5e-24 85.5 0.1 1.1e-23 84.2 0.0 1.7 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain Gmad2 PF10648.9 KUM58274.1 - 0.048 13.9 0.2 1.7 8.9 0.1 3.0 3 0 0 3 3 3 0 Immunoglobulin-like domain of bacterial spore germination TPR_12 PF13424.6 KUM58276.1 - 2.8e-28 98.0 1.0 1.1e-11 44.9 0.1 4.8 3 2 3 6 6 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 KUM58276.1 - 4.7e-24 83.5 0.1 2.9e-06 27.0 0.0 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat Patatin PF01734.22 KUM58276.1 - 1.6e-12 48.0 0.0 4.3e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.22 KUM58276.1 - 5.3e-12 45.5 0.0 2e-11 43.6 0.0 2.0 3 0 0 3 3 3 1 NB-ARC domain TPR_MalT PF17874.1 KUM58276.1 - 3.7e-10 39.7 0.1 2.6e-05 23.8 0.1 2.6 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 KUM58276.1 - 3.7e-09 36.0 2.8 0.045 13.9 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KUM58276.1 - 4.8e-07 29.3 3.8 2.2 8.5 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat NACHT PF05729.12 KUM58276.1 - 2.2e-06 27.7 0.0 4.5e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_19 PF14559.6 KUM58276.1 - 8.6e-06 26.2 0.6 2.7 8.6 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.6 KUM58276.1 - 8.9e-05 22.8 0.0 0.00066 20.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain TPR_1 PF00515.28 KUM58276.1 - 0.00036 20.2 3.1 1.7 8.6 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KUM58276.1 - 0.0027 17.8 5.4 11 6.5 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KUM58276.1 - 0.0033 18.1 0.5 39 5.4 0.0 5.0 3 1 2 5 5 4 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 KUM58276.1 - 0.021 14.6 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TPR_16 PF13432.6 KUM58276.1 - 0.041 14.5 0.1 11 6.7 0.0 4.2 4 2 0 4 4 3 0 Tetratricopeptide repeat Vps39_1 PF10366.9 KUM58276.1 - 0.07 13.4 0.2 18 5.6 0.1 2.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_6 PF13174.6 KUM58276.1 - 0.12 13.1 3.5 51 4.8 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Arylsulfotran_2 PF14269.6 KUM58277.1 - 3.3e-65 220.4 0.3 4.4e-62 210.2 0.3 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KUM58277.1 - 1.1e-10 41.0 0.1 6.8e-09 35.1 0.0 2.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Ectoine_synth PF06339.12 KUM58277.1 - 0.27 11.4 0.9 25 5.1 0.1 2.6 3 0 0 3 3 3 0 Ectoine synthase ABC2_membrane PF01061.24 KUM58278.1 - 8.1e-92 306.4 57.5 2.7e-47 160.9 25.0 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KUM58278.1 - 1.3e-37 129.4 0.0 4.1e-18 66.2 0.0 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KUM58278.1 - 8.6e-28 96.1 0.0 8.6e-28 96.1 0.0 3.6 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KUM58278.1 - 5.4e-21 75.0 0.1 1.3e-20 73.8 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KUM58278.1 - 2.6e-09 36.7 33.3 6.7e-08 32.0 9.9 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KUM58278.1 - 3.2e-05 24.4 0.1 0.26 11.7 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KUM58278.1 - 0.00013 21.9 0.1 0.035 14.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KUM58278.1 - 0.00057 20.4 0.2 0.029 14.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 KUM58278.1 - 0.0022 17.6 0.6 0.012 15.2 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 KUM58278.1 - 0.0045 16.9 0.1 3.9 7.2 0.0 2.7 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KUM58278.1 - 0.007 16.1 1.1 1.2 9.0 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KUM58278.1 - 0.0099 15.6 0.1 0.18 11.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KUM58278.1 - 0.015 15.4 0.2 1.2 9.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KUM58278.1 - 0.02 14.3 0.0 1.9 7.9 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KUM58278.1 - 0.023 15.0 0.1 8.6 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KUM58278.1 - 0.064 13.0 0.3 11 5.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KUM58278.1 - 0.08 13.0 0.3 26 4.9 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase cobW PF02492.19 KUM58278.1 - 0.11 12.1 1.3 2.3 7.8 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KUM58278.1 - 0.13 12.1 2.8 14 5.6 0.1 3.2 3 0 0 3 3 3 0 NACHT domain AAA_17 PF13207.6 KUM58278.1 - 0.21 12.0 0.3 4.9 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.7 KUM58278.1 - 1.5 8.1 9.4 0.44 9.8 2.9 2.6 2 0 0 2 2 2 0 ABC-2 family transporter protein Glyco_transf_90 PF05686.12 KUM58279.1 - 2.7e-14 52.9 0.0 3.6e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Taeniidae_ag PF05596.11 KUM58279.1 - 0.057 13.4 0.1 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Taeniidae antigen Aldose_epim PF01263.20 KUM58280.1 - 4e-49 167.5 0.0 6.5e-49 166.9 0.0 1.3 1 1 0 1 1 1 1 Aldose 1-epimerase Arm-DNA-bind_2 PF12167.8 KUM58280.1 - 0.0094 15.9 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 1 Arm DNA-binding domain Fer2_4 PF13510.6 KUM58280.1 - 0.055 13.5 0.0 0.55 10.3 0.0 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain SH3BGR PF04908.15 KUM58281.1 - 0.00031 20.8 0.0 0.0012 19.0 0.0 2.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein G-patch PF01585.23 KUM58283.1 - 5e-12 45.5 0.6 8.5e-12 44.8 0.6 1.4 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KUM58283.1 - 1.1e-07 31.6 0.0 0.0041 16.9 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 KUM58283.1 - 2.1e-07 30.1 4.7 4.3e-07 29.1 4.7 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 KUM58283.1 - 8.3e-07 29.0 0.2 2.2e-06 27.7 0.2 1.7 1 0 0 1 1 1 1 G-patch domain RED_N PF07808.13 KUM58283.1 - 0.01 15.4 0.5 0.01 15.4 0.5 1.8 2 0 0 2 2 2 0 RED-like protein N-terminal region DUF3433 PF11915.8 KUM58285.1 - 3.7e-33 113.8 25.7 5.9e-26 90.8 3.3 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) SUR7 PF06687.12 KUM58286.1 - 2.2e-25 89.5 13.7 3.1e-25 89.1 13.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family Casein PF00363.18 KUM58286.1 - 0.1 13.0 1.1 0.18 12.2 1.1 1.3 1 0 0 1 1 1 0 Casein CD34_antigen PF06365.12 KUM58286.1 - 0.26 10.9 0.2 0.51 9.9 0.0 1.5 2 0 0 2 2 2 0 CD34/Podocalyxin family AWPM-19 PF05512.11 KUM58287.1 - 0.078 13.2 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 AWPM-19-like family FAD_binding_4 PF01565.23 KUM58288.1 - 2.3e-07 30.6 5.1 2.3e-07 30.6 5.1 1.8 1 1 1 2 2 2 1 FAD binding domain DUF1479 PF07350.12 KUM58289.1 - 8.8e-145 482.6 0.3 1.8e-123 412.4 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.13 KUM58289.1 - 0.097 12.9 0.1 0.46 10.7 0.1 2.0 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) MoaE PF02391.17 KUM58290.1 - 4.4e-35 120.4 0.0 5.4e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 MoaE protein Alpha-amylase PF00128.24 KUM58291.1 - 1.9e-110 369.6 3.4 3e-110 369.0 3.4 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KUM58291.1 - 7.6e-07 29.2 0.0 1.6e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KUM58291.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Peptidase_S10 PF00450.22 KUM58292.1 - 3.6e-64 217.7 1.5 9e-64 216.4 1.5 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase PhyH PF05721.13 KUM58293.1 - 3.8e-12 46.9 0.0 8.9e-11 42.4 0.0 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ETF PF01012.21 KUM58294.1 - 1.2e-43 149.2 0.3 1.4e-43 148.9 0.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ribosomal_L20 PF00453.18 KUM58294.1 - 0.041 14.0 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L20 Pkinase PF00069.25 KUM58295.1 - 3.3e-10 39.8 0.0 4.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM58295.1 - 1.4e-06 27.8 0.0 3.1e-06 26.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Ysc84 PF04366.12 KUM58296.1 - 1.2e-47 160.9 0.0 2e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator LysM PF01476.20 KUM58298.1 - 0.00055 19.9 0.1 0.001 19.1 0.1 1.4 1 0 0 1 1 1 1 LysM domain SKIP_SNW PF02731.15 KUM58298.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 SKIP/SNW domain PARP PF00644.20 KUM58299.1 - 1.1e-32 113.3 0.6 3.1e-31 108.5 0.0 2.9 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KUM58299.1 - 0.00039 20.5 0.0 0.00069 19.7 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain BTB PF00651.31 KUM58300.1 - 1.1e-05 25.6 0.0 2.2e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain DUF3328 PF11807.8 KUM58301.1 - 3.4e-36 125.1 0.6 4.2e-36 124.8 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PhyH PF05721.13 KUM58302.1 - 1.6e-09 38.3 0.1 3.2e-09 37.4 0.1 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KUM58302.1 - 1.1e-07 31.0 0.3 0.045 12.5 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) DPRP PF04244.13 KUM58302.1 - 0.098 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein PhyH PF05721.13 KUM58303.1 - 1.5e-22 80.9 0.0 2.5e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PBP PF01161.20 KUM58304.1 - 1.8e-14 54.2 0.1 2.2e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Fungal_trans_2 PF11951.8 KUM58305.1 - 1.5e-29 103.0 2.8 3.3e-29 101.9 2.8 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-met PF12874.7 KUM58306.1 - 1.3e-20 73.1 38.8 2.1e-06 27.9 0.7 7.2 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KUM58306.1 - 7.3e-19 66.8 35.5 0.028 15.2 0.2 8.6 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KUM58306.1 - 1.2e-14 54.2 45.7 5.2e-05 23.4 1.9 7.9 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KUM58306.1 - 8.4e-13 48.5 41.3 0.0069 16.7 0.8 7.9 2 2 6 8 8 8 5 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KUM58306.1 - 3.9e-10 39.6 43.0 0.12 12.9 0.2 8.3 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KUM58306.1 - 0.00024 21.0 37.8 0.16 12.0 0.2 7.7 7 0 0 7 7 7 4 C2H2-type zinc finger zf_UBZ PF18439.1 KUM58306.1 - 0.0047 16.5 1.2 0.0047 16.5 1.2 6.3 7 0 0 7 7 7 1 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 KUM58306.1 - 0.034 14.6 37.0 0.23 12.0 0.2 8.2 8 0 0 8 8 8 0 Zinc-finger double domain zinc_ribbon_9 PF14369.6 KUM58306.1 - 0.059 13.6 0.2 0.059 13.6 0.2 4.9 5 0 0 5 5 5 0 zinc-ribbon zf-C2H2_11 PF16622.5 KUM58306.1 - 0.63 9.8 15.8 18 5.2 0.4 5.4 5 0 0 5 5 5 0 zinc-finger C2H2-type LIM PF00412.22 KUM58306.1 - 2.6 8.4 34.0 0.24 11.6 3.1 5.2 3 2 2 5 5 5 0 LIM domain GPR15L PF15854.5 KUM58306.1 - 6.6 7.0 8.1 1.5 9.1 3.9 2.1 2 0 0 2 2 2 0 G-protein coupled receptor ligand 15 Csm1 PF12539.8 KUM58307.1 - 0.012 16.2 0.1 0.18 12.5 0.0 2.3 2 0 0 2 2 2 0 Chromosome segregation protein Csm1/Pcs1 E1_DerP2_DerF2 PF02221.15 KUM58307.1 - 0.039 14.4 0.1 0.33 11.4 0.0 2.2 2 0 0 2 2 2 0 ML domain tRNA_lig_CPD PF08302.11 KUM58308.1 - 2.5e-90 302.3 0.0 3.9e-90 301.7 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 KUM58308.1 - 9.1e-84 280.7 0.1 1.9e-83 279.7 0.1 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KUM58308.1 - 4.4e-49 166.8 0.0 8e-49 165.9 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 KUM58308.1 - 0.01 16.4 0.1 0.15 12.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Gene66 PF02053.15 KUM58308.1 - 0.07 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Gene 66 (IR5) protein PAP2 PF01569.21 KUM58309.1 - 2.6e-25 88.8 1.6 5.8e-25 87.6 1.6 1.6 1 0 0 1 1 1 1 PAP2 superfamily Sulf_transp PF04143.14 KUM58309.1 - 0.0017 18.0 2.6 0.0028 17.3 1.0 1.8 1 1 0 2 2 2 1 Sulphur transport Abhydrolase_1 PF00561.20 KUM58310.1 - 1.1e-16 61.2 0.0 8.9e-15 55.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KUM58310.1 - 1.8e-13 50.5 0.0 4.1e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Mod_r PF07200.13 KUM58311.1 - 2.2e-25 89.5 3.3 2.7e-25 89.2 3.3 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein RcbX PF02341.15 KUM58311.1 - 0.0069 16.6 0.1 0.011 15.9 0.1 1.4 1 0 0 1 1 1 1 RbcX protein Fib_alpha PF08702.10 KUM58311.1 - 0.016 15.4 0.2 0.026 14.7 0.2 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CDPS PF16715.5 KUM58311.1 - 1.8 8.2 6.3 1.7 8.3 0.6 2.1 1 1 1 2 2 2 0 Cyclodipeptide synthase PSK_trans_fac PF07704.11 KUM58311.1 - 2.1 9.1 6.0 0.46 11.3 1.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor ATG16 PF08614.11 KUM58311.1 - 8.6 6.5 13.6 1.7 8.9 9.4 2.1 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Ank_2 PF12796.7 KUM58313.1 - 1.2e-92 304.6 7.3 1.5e-19 70.4 0.0 7.3 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 KUM58313.1 - 4.1e-64 210.4 10.5 1.7e-06 28.2 0.0 12.7 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.6 KUM58313.1 - 1.1e-58 194.9 5.3 1.4e-12 47.9 0.1 9.8 5 2 6 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM58313.1 - 5.3e-56 180.0 4.7 2.4e-05 24.4 0.0 12.5 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 KUM58313.1 - 1.1e-46 156.3 12.6 8.4e-07 29.2 0.0 9.2 3 3 5 9 9 9 8 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 KUM58313.1 - 1.9e-10 40.4 2.0 2.1e-09 37.0 2.0 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.6 KUM58313.1 - 5e-05 23.6 0.0 0.00018 21.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain Imm_superinfect PF14373.6 KUM58313.1 - 0.0056 16.6 0.2 1.2e+02 2.7 0.0 5.9 7 0 0 7 7 7 0 Superinfection immunity protein NACHT PF05729.12 KUM58313.1 - 0.0073 16.2 0.0 0.02 14.8 0.0 1.8 2 0 0 2 2 2 1 NACHT domain Ank_5 PF13857.6 KUM58314.1 - 3e-10 40.1 0.1 3e-08 33.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KUM58314.1 - 2.1e-08 34.5 0.1 2e-06 28.2 0.1 2.6 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM58314.1 - 2.1e-07 30.7 0.6 3.4e-05 23.9 0.1 3.4 3 1 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KUM58314.1 - 5.1e-07 30.2 0.1 9.1e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KUM58314.1 - 0.0023 18.3 0.0 0.015 15.7 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat YejG PF13989.6 KUM58314.1 - 0.0074 16.7 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 YejG-like protein Got1 PF04178.12 KUM58316.1 - 8.9e-36 122.7 15.0 1.2e-35 122.3 15.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 KUM58316.1 - 3 6.0 5.9 3.8 5.7 5.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HLH PF00010.26 KUM58317.1 - 6e-12 45.3 0.0 3.2e-11 43.0 0.0 2.2 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain RTA1 PF04479.13 KUM58319.1 - 3.3e-55 186.9 10.2 3.3e-55 186.9 10.2 1.6 1 1 1 2 2 2 1 RTA1 like protein TMEM190 PF15431.6 KUM58319.1 - 0.1 12.8 0.1 0.26 11.5 0.1 1.6 1 1 0 1 1 1 0 Transmembrane protein 190 YrhC PF14143.6 KUM58319.1 - 8.7 6.5 12.0 0.44 10.7 0.1 3.6 3 1 2 5 5 5 0 YrhC-like protein adh_short_C2 PF13561.6 KUM58320.1 - 1.6e-54 184.9 0.1 1.9e-54 184.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM58320.1 - 2e-45 154.6 0.2 2.6e-45 154.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM58320.1 - 3e-10 40.3 0.2 4.3e-10 39.8 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM58320.1 - 5e-06 26.2 0.1 8e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KUM58320.1 - 0.021 14.0 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NusB PF01029.18 KUM58320.1 - 0.036 14.3 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 NusB family DFP PF04127.15 KUM58320.1 - 0.11 12.3 0.2 0.35 10.7 0.2 1.8 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Aquarius_N PF16399.5 KUM58321.1 - 5.9e-278 924.2 0.0 7.4e-278 923.9 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KUM58321.1 - 2.9e-26 92.3 0.0 4.9e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KUM58321.1 - 3.2e-21 76.3 0.0 9.2e-21 74.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KUM58321.1 - 1e-07 31.9 0.0 0.00036 20.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KUM58321.1 - 1.4e-06 28.7 0.0 4.4e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KUM58321.1 - 5.7e-06 26.4 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KUM58321.1 - 0.00047 20.0 0.1 0.093 12.4 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 KUM58321.1 - 0.0032 16.9 0.1 0.018 14.4 0.0 2.2 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain UvrD_C_2 PF13538.6 KUM58321.1 - 0.0032 17.3 1.9 0.034 14.0 0.3 2.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KUM58321.1 - 0.0035 17.8 0.0 0.017 15.5 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 KUM58321.1 - 0.019 14.2 0.8 0.046 12.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KUM58321.1 - 0.02 15.3 0.0 0.07 13.5 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KUM58321.1 - 0.04 13.9 0.0 0.66 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 KUM58321.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD-helicase PF00580.21 KUM58321.1 - 0.054 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KUM58321.1 - 0.056 13.7 0.2 0.33 11.2 0.1 2.3 1 1 1 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 KUM58321.1 - 0.095 11.5 0.1 0.28 9.9 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein PIF1 PF05970.14 KUM58321.1 - 0.13 11.4 0.0 5.2 6.1 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase RNA_helicase PF00910.22 KUM58321.1 - 0.2 12.0 0.0 0.84 10.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase 4HBT PF03061.22 KUM58322.1 - 3.8e-14 52.8 0.0 5.6e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KUM58322.1 - 0.019 15.2 0.0 0.021 15.1 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF4442 PF14539.6 KUM58322.1 - 0.04 14.1 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Ada_Zn_binding PF02805.16 KUM58325.1 - 6.5e-29 99.8 5.3 1.1e-28 99.1 5.3 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KUM58325.1 - 1.9e-08 34.2 0.0 4.3e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KUM58325.1 - 0.00018 21.7 0.0 0.00042 20.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain TGT PF01702.18 KUM58326.1 - 4.3e-35 121.5 0.0 5.3e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase TGT PF01702.18 KUM58327.1 - 4.5e-90 302.3 0.1 5.1e-90 302.1 0.1 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylat_synt PF00303.19 KUM58328.1 - 4.1e-103 344.2 0.0 4.7e-103 344.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase MFS_1 PF07690.16 KUM58329.1 - 1.9e-32 112.6 28.8 2.6e-32 112.1 28.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM58329.1 - 3.2e-06 26.3 14.1 0.019 13.8 0.0 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter Aldo_ket_red PF00248.21 KUM58330.1 - 8.3e-66 222.2 0.0 9.4e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 KUM58331.1 - 5.7e-06 26.4 9.9 1.2e-05 25.3 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM58331.1 - 0.00063 18.7 6.3 0.0015 17.4 6.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ldl_recept_a PF00057.18 KUM58331.1 - 0.59 10.4 3.9 1.3 9.3 3.9 1.7 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A zf-AN1 PF01428.16 KUM58332.1 - 1.1e-22 79.9 26.3 6.5e-12 45.4 8.3 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 KUM58332.1 - 0.0071 16.5 6.1 0.0071 16.5 6.1 2.7 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 KUM58332.1 - 0.15 12.5 15.3 1.2 9.5 4.2 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zinc_ribbon_4 PF13717.6 KUM58332.1 - 0.69 9.9 9.0 1.2 9.1 0.7 2.7 2 0 0 2 2 2 0 zinc-ribbon domain C1_4 PF07975.12 KUM58332.1 - 1.3 9.3 20.3 8.1 6.8 4.5 3.3 2 2 0 2 2 2 0 TFIIH C1-like domain zinc_ribbon_5 PF13719.6 KUM58332.1 - 1.5 8.6 5.9 9.8 6.0 0.6 2.9 2 0 0 2 2 2 0 zinc-ribbon domain MFS_1 PF07690.16 KUM58333.1 - 1.1e-25 90.3 33.9 1.6e-25 89.8 33.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2975 PF11188.8 KUM58333.1 - 0.092 12.6 0.1 0.092 12.6 0.1 3.2 4 1 1 5 5 5 0 Protein of unknown function (DUF2975) efThoc1 PF11957.8 KUM58334.1 - 2.4e-152 508.1 4.0 3.9e-152 507.3 4.0 1.3 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Aquarius_N PF16399.5 KUM58335.1 - 1.8e-30 105.7 1.5 2.2e-30 105.4 1.5 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus Tfb2 PF03849.14 KUM58336.1 - 1.1e-135 452.3 0.0 1.8e-135 451.5 0.0 1.3 2 0 0 2 2 2 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KUM58336.1 - 9.3e-24 83.6 0.6 1.7e-23 82.8 0.6 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KUM58336.1 - 4.9e-05 23.5 0.0 0.00046 20.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ANATO PF01821.18 KUM58337.1 - 0.089 13.7 3.1 13 6.8 1.4 3.0 2 1 0 2 2 2 0 Anaphylotoxin-like domain Pectate_lyase_3 PF12708.7 KUM58338.1 - 1.4e-102 342.1 12.2 2.7e-88 295.4 7.4 2.7 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KUM58338.1 - 1.3e-06 28.0 0.8 0.039 13.6 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Aminotran_1_2 PF00155.21 KUM58339.1 - 1.8e-17 63.6 0.0 2.4e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KUM58339.1 - 0.022 13.6 0.0 0.3 9.8 0.0 2.1 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase AflR PF08493.10 KUM58340.1 - 1.2e-11 44.6 0.2 1.8e-11 44.1 0.2 1.3 1 0 0 1 1 1 1 Aflatoxin regulatory protein Fungal_trans_2 PF11951.8 KUM58341.1 - 4.7e-09 35.5 0.6 1.8e-08 33.6 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM58341.1 - 1.7e-06 28.0 9.2 3.3e-06 27.1 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 KUM58342.1 - 3.2e-72 242.5 11.6 3.2e-72 242.5 11.6 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF3169 PF11368.8 KUM58342.1 - 0.0017 18.0 1.0 0.0017 18.0 1.0 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF3169) Pyr_redox_2 PF07992.14 KUM58343.1 - 7.2e-35 120.6 0.0 8e-33 113.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM58343.1 - 1e-08 35.6 0.0 5.8e-08 33.2 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HSP20 PF00011.21 KUM58344.1 - 6.1e-07 29.5 0.1 9.5e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KUM58344.1 - 0.0093 15.5 0.1 0.061 12.9 0.1 2.1 1 1 1 2 2 2 1 HSP20-like domain found in ArsA NLPC_P60 PF00877.19 KUM58346.1 - 6.2e-19 68.0 0.0 1.2e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family SH3_3 PF08239.11 KUM58346.1 - 0.00088 19.5 0.1 0.0018 18.5 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Amidase_5 PF05382.13 KUM58346.1 - 0.0016 18.4 1.8 0.0028 17.6 0.1 2.1 1 1 2 3 3 3 1 Bacteriophage peptidoglycan hydrolase DUF1175 PF06672.11 KUM58346.1 - 0.016 14.9 0.0 2.3 7.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1175) Aa_trans PF01490.18 KUM58347.1 - 2.5e-20 72.6 36.8 2.9e-20 72.4 36.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Methyltransf_2 PF00891.18 KUM58348.1 - 1.6e-18 66.8 0.0 2.3e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KUM58348.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain Amidase PF01425.21 KUM58349.1 - 3.9e-86 289.8 0.0 5.1e-86 289.4 0.0 1.1 1 0 0 1 1 1 1 Amidase Ribosomal_L16 PF00252.18 KUM58350.1 - 1e-41 142.0 0.2 1.3e-41 141.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e S6PP_C PF08472.10 KUM58351.1 - 0.057 13.3 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal Ank_2 PF12796.7 KUM58352.1 - 9.7e-51 170.3 0.2 2.1e-14 53.9 0.2 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KUM58352.1 - 4.8e-38 128.0 7.4 6.8e-06 26.3 0.1 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 KUM58352.1 - 1e-35 121.7 9.8 9.4e-13 48.4 0.1 6.6 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM58352.1 - 5.8e-35 115.4 7.9 0.00043 20.5 0.0 8.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KUM58352.1 - 9.3e-32 108.7 8.0 8.5e-09 35.5 0.3 6.6 2 2 4 6 6 6 6 Ankyrin repeats (many copies) CorA PF01544.18 KUM58352.1 - 2e-13 50.3 0.8 4.3e-13 49.2 0.8 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Arrestin_C PF02752.22 KUM58353.1 - 1.1e-06 29.1 0.1 4.6e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KUM58353.1 - 0.0021 18.2 0.2 0.085 12.9 0.0 2.7 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain YchF-GTPase_C PF06071.13 KUM58354.1 - 3.4e-36 123.3 0.0 8.1e-36 122.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KUM58354.1 - 5.6e-21 74.8 0.0 1.5e-20 73.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KUM58354.1 - 9.3e-07 28.5 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF2855 PF11017.8 KUM58356.1 - 3.6e-97 326.2 0.2 4.2e-97 325.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Methyltransf_28 PF02636.17 KUM58356.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF1275 PF06912.11 KUM58356.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1275) Chitin_synth_2 PF03142.15 KUM58357.1 - 2.2e-290 963.8 0.3 2.8e-290 963.4 0.3 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KUM58357.1 - 4.9e-12 46.2 4.1 1.7e-11 44.4 4.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KUM58357.1 - 3.8e-09 36.8 0.0 3.4e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KUM58357.1 - 0.0004 20.2 0.0 0.035 13.9 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KUM58357.1 - 0.0032 17.0 0.1 0.0093 15.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cyt-b5 PF00173.28 KUM58357.1 - 0.15 12.2 0.1 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.32 KUM58359.1 - 8.6e-06 26.4 1.6 0.00019 22.2 0.2 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF2415 PF10313.9 KUM58359.1 - 0.065 13.2 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) DUF3759 PF12585.8 KUM58360.1 - 0.0077 16.2 1.0 0.0077 16.2 1.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3759) Sel1 PF08238.12 KUM58362.1 - 1.6e-41 139.8 20.5 2.5e-07 31.1 0.0 7.5 7 0 0 7 7 7 7 Sel1 repeat TPR_19 PF14559.6 KUM58362.1 - 3.1 8.4 5.0 6.1 7.4 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat COesterase PF00135.28 KUM58363.1 - 7.6e-15 54.8 0.0 9e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 KUM58364.1 - 2.4e-23 82.8 0.0 3.4e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Fungal_trans PF04082.18 KUM58365.1 - 2.7e-09 36.5 0.6 7.9e-09 34.9 0.1 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Tis11B_N PF04553.12 KUM58365.1 - 0.31 11.6 2.3 0.62 10.6 2.3 1.4 1 0 0 1 1 1 0 Tis11B like protein, N terminus zf-C2H2_4 PF13894.6 KUM58366.1 - 0.0077 17.0 3.3 0.016 16.0 3.3 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-Di19 PF05605.12 KUM58366.1 - 0.012 15.9 0.7 0.02 15.2 0.7 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KUM58366.1 - 0.022 15.0 1.2 0.033 14.5 1.2 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KUM58366.1 - 0.028 14.9 3.6 0.052 14.0 3.6 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type AA_permease_2 PF13520.6 KUM58367.1 - 1.5e-68 231.6 45.8 1.8e-68 231.3 45.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM58367.1 - 7.8e-16 57.7 35.2 1.1e-15 57.2 35.2 1.2 1 0 0 1 1 1 1 Amino acid permease Pericardin_rpt PF07054.11 KUM58369.1 - 3.1 8.0 8.0 4.7 7.4 2.7 2.8 2 1 0 2 2 2 0 Pericardin like repeat SUR7 PF06687.12 KUM58370.1 - 1.6e-20 73.7 6.7 1.9e-20 73.4 6.7 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KUM58370.1 - 7.4 6.4 14.6 5.1 7.0 9.5 2.5 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Mannitol_dh_C PF08125.13 KUM58371.1 - 5.9e-43 147.1 0.0 9.1e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KUM58371.1 - 5.4e-18 65.6 1.3 9.1e-18 64.9 0.2 1.8 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain B12-binding PF02310.19 KUM58371.1 - 0.018 15.0 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain 3HCDH_N PF02737.18 KUM58371.1 - 0.027 14.3 0.3 0.064 13.1 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 KUM58371.1 - 0.059 13.7 0.6 22 5.4 0.1 3.7 4 0 0 4 4 4 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Pkinase PF00069.25 KUM58372.1 - 3.3e-64 216.8 0.0 3.9e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM58372.1 - 1.3e-28 100.0 0.0 1.8e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KUM58372.1 - 3.7e-10 40.3 0.2 6.8e-10 39.5 0.2 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KUM58372.1 - 1.1e-06 27.8 0.0 1.5e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KUM58372.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF1907 PF08925.11 KUM58373.1 - 6.4e-81 271.9 0.0 7.6e-81 271.6 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) ECH_1 PF00378.20 KUM58374.1 - 2.3e-45 154.9 0.1 3.3e-45 154.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KUM58374.1 - 1.9e-22 80.2 0.5 4.9e-22 78.9 0.5 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DoxD PF04173.13 KUM58374.1 - 0.076 12.9 2.5 0.11 12.4 0.1 1.9 2 0 0 2 2 2 0 TQO small subunit DoxD DUF5572 PF17733.1 KUM58374.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5572) ZZ PF00569.17 KUM58375.1 - 1.1e-10 41.2 4.8 1.8e-10 40.5 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 KUM58375.1 - 3.4e-10 40.0 0.0 8.4e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KUM58375.1 - 1.7e-08 34.7 0.1 5.1e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain Phage_Mu_Gam PF07352.12 KUM58375.1 - 1.3 9.0 5.9 14 5.6 0.1 2.7 2 1 1 3 3 3 0 Bacteriophage Mu Gam like protein Thioredoxin PF00085.20 KUM58376.1 - 4.9e-37 126.0 0.0 2.9e-23 81.8 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KUM58376.1 - 1.5e-11 44.6 0.0 4.2e-05 23.5 0.0 4.3 3 1 1 4 4 4 2 Thioredoxin-like domain AhpC-TSA PF00578.21 KUM58376.1 - 0.00031 20.6 0.2 1.2 9.0 0.0 3.1 3 0 0 3 3 3 2 AhpC/TSA family HyaE PF07449.11 KUM58376.1 - 0.00038 20.4 0.0 0.24 11.4 0.0 2.9 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 KUM58376.1 - 0.0027 18.0 0.1 5 7.5 0.1 3.8 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_3 PF13192.6 KUM58376.1 - 0.081 13.0 0.1 2.4 8.3 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin domain TraF PF13728.6 KUM58376.1 - 0.12 12.2 0.1 37 4.0 0.0 3.3 4 0 0 4 4 4 0 F plasmid transfer operon protein OST3_OST6 PF04756.13 KUM58376.1 - 0.13 11.6 0.0 6.3 6.1 0.0 2.5 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family QCR10 PF09796.9 KUM58377.1 - 1.4e-23 82.7 0.1 1.9e-23 82.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Coatomer_WDAD PF04053.14 KUM58378.1 - 4.7e-169 563.1 0.0 2.7e-168 560.6 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KUM58378.1 - 2.7e-38 129.2 7.3 1.8e-06 28.5 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM58378.1 - 3.9e-07 30.3 0.0 2.9 8.3 0.0 6.0 3 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KUM58378.1 - 0.00015 20.5 1.6 0.2 10.3 0.0 3.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KUM58378.1 - 0.027 14.5 0.0 9.8 6.3 0.0 3.9 1 1 3 4 4 4 0 Ciliary BBSome complex subunit 2, middle region ETC_C1_NDUFA5 PF04716.14 KUM58379.1 - 1.4e-26 92.0 1.8 8e-25 86.4 0.0 2.7 3 0 0 3 3 3 2 ETC complex I subunit conserved region Ku_PK_bind PF08785.11 KUM58379.1 - 0.036 14.2 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 Ku C terminal domain like RF-1 PF00472.20 KUM58380.1 - 1.8e-20 73.0 2.5 2.8e-20 72.4 2.5 1.3 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 KUM58380.1 - 0.023 15.1 1.1 0.1 13.0 0.5 2.0 1 1 0 2 2 2 0 Mitochondrial ribosomal subunit protein NiFe-hyd_HybE PF11939.8 KUM58380.1 - 0.027 14.4 0.2 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 [NiFe]-hydrogenase assembly, chaperone, HybE RRM_1 PF00076.22 KUM58381.1 - 3.4e-05 23.6 0.0 6.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SYS1 PF09801.9 KUM58382.1 - 3.5e-30 105.0 1.0 4e-30 104.8 1.0 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network COX6B PF02297.17 KUM58384.1 - 1.3e-23 83.0 4.3 1.7e-23 82.6 4.3 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 KUM58384.1 - 0.0066 16.7 1.6 0.015 15.5 1.7 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Lactamase_B_6 PF16661.5 KUM58385.1 - 4.5e-65 218.7 0.0 9.8e-65 217.6 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KUM58385.1 - 1.4e-46 158.8 0.1 1.4e-46 158.8 0.1 1.8 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KUM58385.1 - 3.7e-15 56.2 0.0 2.6e-14 53.4 0.0 2.3 2 1 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 KUM58385.1 - 6e-12 45.3 0.0 1.6e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KUM58385.1 - 0.024 14.6 0.1 0.076 13.0 0.1 1.8 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily AA_permease_2 PF13520.6 KUM58386.1 - 1.8e-60 204.9 42.0 2.3e-60 204.6 42.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM58386.1 - 9.1e-21 74.0 36.4 1.2e-20 73.6 36.4 1.0 1 0 0 1 1 1 1 Amino acid permease U3_assoc_6 PF08640.11 KUM58387.1 - 1.9e-29 101.6 1.1 1.9e-29 101.6 1.1 1.8 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KUM58387.1 - 2.6e-06 27.8 1.1 0.0097 16.7 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat Suf PF05843.14 KUM58387.1 - 5.4e-05 23.3 0.3 0.015 15.3 0.0 2.6 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_15 PF13429.6 KUM58387.1 - 0.00019 20.8 0.0 0.044 13.0 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat NRDE-2 PF08424.10 KUM58387.1 - 0.033 13.3 0.0 0.071 12.2 0.1 1.5 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference Frag1 PF10277.9 KUM58388.1 - 1.4e-42 145.8 7.9 1.4e-42 145.8 7.9 2.7 2 0 0 2 2 2 2 Frag1/DRAM/Sfk1 family FAM104 PF15434.6 KUM58390.1 - 0.42 11.2 11.1 0.49 11.0 5.5 2.6 2 0 0 2 2 2 0 Family 104 Sec23_trunk PF04811.15 KUM58391.1 - 1.3e-53 182.1 0.0 2.9e-53 180.9 0.0 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KUM58391.1 - 2.7e-25 88.1 0.0 6e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KUM58391.1 - 3.6e-17 62.9 0.0 6.9e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KUM58391.1 - 9e-16 57.6 5.2 1.8e-15 56.7 5.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KUM58391.1 - 6e-08 32.5 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat DUF1678 PF07913.11 KUM58391.1 - 0.091 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) ABC_tran PF00005.27 KUM58393.1 - 1.9e-50 170.9 0.0 5.7e-25 88.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 KUM58393.1 - 8.9e-50 169.0 31.1 1.6e-29 102.8 8.8 2.4 2 0 0 2 2 2 2 ABC-2 type transporter AAA_16 PF13191.6 KUM58393.1 - 7.2e-11 42.8 0.1 0.00046 20.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KUM58393.1 - 1.4e-09 38.1 0.4 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KUM58393.1 - 2.3e-09 37.5 10.1 0.0019 18.1 0.1 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KUM58393.1 - 4.4e-08 32.8 1.7 0.00031 20.2 0.2 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KUM58393.1 - 5.7e-08 33.5 0.1 0.00088 19.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KUM58393.1 - 3e-07 30.1 1.5 0.014 15.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KUM58393.1 - 3.6e-06 27.3 0.0 0.072 13.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 KUM58393.1 - 1.5e-05 24.2 0.3 0.0087 15.1 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein NACHT PF05729.12 KUM58393.1 - 2.8e-05 24.1 0.0 0.038 13.9 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.6 KUM58393.1 - 4.7e-05 23.1 0.0 0.14 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KUM58393.1 - 5.8e-05 22.9 0.7 0.11 12.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KUM58393.1 - 0.00011 22.3 1.4 0.05 13.7 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KUM58393.1 - 0.00021 21.6 0.1 1.2 9.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain cobW PF02492.19 KUM58393.1 - 0.00026 20.6 0.3 0.28 10.7 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KUM58393.1 - 0.00044 20.6 0.0 1 9.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA PF00004.29 KUM58393.1 - 0.00045 20.7 0.0 0.73 10.3 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KUM58393.1 - 0.00047 20.1 0.0 0.077 12.9 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KUM58393.1 - 0.00062 19.8 0.0 0.3 11.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 KUM58393.1 - 0.0011 18.4 0.2 0.35 10.2 0.0 2.3 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_15 PF13175.6 KUM58393.1 - 0.0017 18.1 0.0 1.6 8.3 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain Roc PF08477.13 KUM58393.1 - 0.0023 18.2 0.1 2.5 8.3 0.0 2.8 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 KUM58393.1 - 0.0033 17.6 0.0 1 9.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 KUM58393.1 - 0.0034 17.9 0.1 0.76 10.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KUM58393.1 - 0.0063 16.3 0.1 4.5 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KUM58393.1 - 0.018 14.3 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain FtsK_SpoIIIE PF01580.18 KUM58393.1 - 0.019 14.4 0.0 2.7 7.3 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_11 PF13086.6 KUM58393.1 - 0.02 14.7 0.1 0.66 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 KUM58393.1 - 0.02 14.3 0.2 2.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_19 PF13245.6 KUM58393.1 - 0.021 15.2 0.1 8.1 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KUM58393.1 - 0.022 14.5 1.3 0.69 9.6 0.0 2.6 3 0 0 3 3 2 0 Cytidylate kinase Zeta_toxin PF06414.12 KUM58393.1 - 0.033 13.5 0.1 8.6 5.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 KUM58393.1 - 0.034 14.1 0.2 8.1 6.3 0.0 2.7 3 0 0 3 3 2 0 NTPase PRK PF00485.18 KUM58393.1 - 0.037 13.8 0.3 4.4 7.0 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family PhoH PF02562.16 KUM58393.1 - 0.056 12.9 0.1 12 5.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF87 PF01935.17 KUM58393.1 - 0.059 13.4 0.5 1.7 8.7 0.4 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 KUM58393.1 - 0.074 13.1 2.2 4.5 7.3 0.2 2.4 2 0 0 2 2 2 0 Dynamin family PIF1 PF05970.14 KUM58393.1 - 0.08 12.1 0.1 5.2 6.1 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase ATP_bind_1 PF03029.17 KUM58393.1 - 0.087 12.6 0.1 9.6 5.9 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KUM58393.1 - 0.089 12.5 0.2 7.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 KUM58393.1 - 0.092 12.6 0.2 16 5.4 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.9 KUM58393.1 - 0.094 11.9 0.1 4 6.6 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATP-synt_ab PF00006.25 KUM58393.1 - 0.095 12.3 0.0 5.9 6.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 KUM58393.1 - 0.1 12.1 0.2 7.3 6.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF4388 PF14332.6 KUM58393.1 - 0.11 12.7 0.1 2.3 8.5 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4388) NB-ARC PF00931.22 KUM58393.1 - 0.12 11.6 0.0 2.6 7.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Pox_A32 PF04665.12 KUM58393.1 - 0.2 11.1 0.8 12 5.3 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein SRP54 PF00448.22 KUM58393.1 - 0.21 11.2 0.2 19 4.8 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_35 PF14516.6 KUM58393.1 - 0.25 10.2 0.3 4.6 6.0 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain DUF2627 PF11118.8 KUM58393.1 - 3.2 8.4 5.8 2.8 8.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) Prenyltrans PF00432.21 KUM58394.1 - 2.1e-34 116.9 11.3 3e-07 30.0 0.2 6.4 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KUM58394.1 - 0.0051 15.9 0.0 0.079 12.0 0.0 2.6 2 1 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain Pkinase PF00069.25 KUM58395.1 - 1.2e-66 224.8 0.0 1.8e-66 224.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM58395.1 - 1.6e-42 145.6 0.0 2.3e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM58395.1 - 1e-07 31.6 0.0 3.9e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KUM58395.1 - 2.3e-06 26.8 0.1 2.3e-06 26.8 0.1 2.2 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KUM58395.1 - 0.0057 16.0 0.2 0.022 14.1 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KUM58395.1 - 0.21 11.5 3.6 0.95 9.3 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family FNIP PF05725.12 KUM58396.1 - 0.16 12.2 0.6 2.5 8.3 0.0 3.2 5 0 0 5 5 5 0 FNIP Repeat DUF1357 PF07094.11 KUM58398.1 - 0.086 12.9 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) Ank_2 PF12796.7 KUM58400.1 - 7.7e-38 129.0 14.4 9.6e-12 45.3 0.6 4.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM58400.1 - 3e-34 116.9 9.5 1.2e-07 32.1 0.0 8.6 4 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 KUM58400.1 - 6.8e-32 108.5 20.1 0.00011 22.5 0.1 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KUM58400.1 - 1.4e-23 82.6 10.7 2.9e-07 30.6 0.4 5.9 4 3 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM58400.1 - 4.3e-22 75.8 9.3 0.0043 17.4 0.0 9.3 8 1 0 8 8 8 6 Ankyrin repeat CBFD_NFYB_HMF PF00808.23 KUM58401.1 - 4.8e-29 100.4 0.6 6.5e-29 100.0 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KUM58401.1 - 3.3e-06 27.5 0.0 5.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KUM58401.1 - 0.00025 21.0 0.0 0.0004 20.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KUM58401.1 - 0.00041 20.3 0.1 0.00063 19.7 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 KUM58401.1 - 0.009 16.1 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold MFS_1 PF07690.16 KUM58402.1 - 1.8e-31 109.4 22.8 1.8e-31 109.4 22.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM58402.1 - 1.4e-09 37.4 14.6 1.4e-09 37.4 14.6 3.3 4 1 0 4 4 4 1 Sugar (and other) transporter Ilm1 PF10311.9 KUM58403.1 - 2.1e-49 167.4 0.6 2.6e-49 167.1 0.6 1.1 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 SP24 PF16504.5 KUM58403.1 - 0.024 14.7 0.3 0.052 13.6 0.3 1.5 1 0 0 1 1 1 0 Putative virion membrane protein of plant and insect virus CFEM PF05730.11 KUM58404.1 - 1.8e-11 43.9 13.5 4.6e-11 42.6 13.5 1.7 1 0 0 1 1 1 1 CFEM domain Mucin PF01456.17 KUM58404.1 - 0.18 11.8 26.8 0.31 11.0 26.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Apt1 PF10351.9 KUM58404.1 - 9.1 5.0 8.5 11 4.8 8.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Aegerolysin PF06355.13 KUM58405.1 - 1.6e-25 89.7 0.3 1.9e-25 89.4 0.3 1.1 1 0 0 1 1 1 1 Aegerolysin Eisosome1 PF12757.7 KUM58408.1 - 1.1e-34 119.4 14.5 1.1e-34 119.4 14.5 3.1 3 0 0 3 3 3 1 Eisosome protein 1 Fungal_trans PF04082.18 KUM58410.1 - 1.4e-10 40.7 0.0 2.1e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM58410.1 - 8e-08 32.3 8.9 1.3e-07 31.6 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GP4 PF03010.14 KUM58410.1 - 0.18 11.8 0.1 0.38 10.7 0.1 1.5 1 0 0 1 1 1 0 GP4 Cep3 PF16846.5 KUM58410.1 - 0.26 9.7 0.0 0.39 9.1 0.0 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B MFS_1 PF07690.16 KUM58411.1 - 8.3e-39 133.5 35.9 1.3e-33 116.5 24.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2615 PF11027.8 KUM58411.1 - 0.025 14.7 0.1 0.057 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Metallophos PF00149.28 KUM58412.1 - 1.9e-37 129.7 0.0 3.6e-37 128.9 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short_C2 PF13561.6 KUM58414.1 - 1.2e-24 87.2 0.0 1.4e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM58414.1 - 7.4e-12 45.1 0.0 9.5e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Beta-lactamase PF00144.24 KUM58416.1 - 3e-42 145.1 0.0 8.6e-42 143.5 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase FMO-like PF00743.19 KUM58417.1 - 1.2e-18 66.9 0.3 2.4e-15 56.0 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KUM58417.1 - 2.4e-13 50.0 0.0 1e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM58417.1 - 4.3e-09 36.0 0.0 4.3e-08 32.7 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KUM58417.1 - 1.1e-08 34.7 0.0 5.4e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM58417.1 - 4.2e-08 33.3 0.0 4.9e-06 26.7 0.1 3.0 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KUM58417.1 - 0.0036 17.3 0.7 7.3 6.6 0.1 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KUM58417.1 - 0.0052 15.9 0.0 0.0082 15.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KUM58417.1 - 0.0084 15.2 0.0 0.04 13.0 0.0 2.2 3 1 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.24 KUM58417.1 - 0.018 14.6 0.2 0.32 10.5 0.0 2.5 2 1 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KUM58417.1 - 0.033 13.4 0.1 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KUM58417.1 - 0.042 14.4 0.2 2 9.0 0.2 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KUM58417.1 - 0.19 11.8 0.0 23 5.1 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KUM58417.1 - 0.21 10.2 2.0 0.29 9.8 0.1 2.1 3 0 0 3 3 3 0 HI0933-like protein DUF1996 PF09362.10 KUM58418.1 - 1.2e-82 277.5 0.7 1.2e-82 277.5 0.7 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) zf-C3Hc3H PF13891.6 KUM58418.1 - 0.14 12.6 0.4 0.3 11.5 0.4 1.6 1 0 0 1 1 1 0 Potential DNA-binding domain Ribosomal_S26e PF01283.19 KUM58419.1 - 0.11 13.0 0.3 1.8 9.1 0.2 2.4 1 1 1 2 2 2 0 Ribosomal protein S26e Aldo_ket_red PF00248.21 KUM58421.1 - 8.4e-70 235.3 0.0 9.9e-70 235.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_ABA_S PF18066.1 KUM58421.1 - 0.055 14.2 0.1 1.1 10.0 0.0 2.3 2 0 0 2 2 2 0 Phage ABA sandwich domain WD40 PF00400.32 KUM58423.1 - 0.025 15.5 0.2 0.025 15.5 0.2 5.6 7 0 0 7 7 7 0 WD domain, G-beta repeat Kelch_2 PF07646.15 KUM58423.1 - 0.14 12.2 0.6 1.3 9.2 0.4 2.8 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.6 KUM58423.1 - 0.17 12.2 1.4 2 8.8 0.1 3.3 3 0 0 3 3 3 0 Kelch motif RNA_pol_N PF01194.17 KUM58424.1 - 1.5e-30 105.2 1.4 1.8e-30 105.0 1.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Clr5 PF14420.6 KUM58425.1 - 4.9e-17 61.9 0.6 4.9e-17 61.9 0.6 2.3 2 0 0 2 2 2 1 Clr5 domain YozE_SAM_like PF06855.12 KUM58425.1 - 0.045 13.9 0.5 11 6.2 0.0 2.9 3 0 0 3 3 3 0 YozE SAM-like fold DUF2407_C PF13373.6 KUM58425.1 - 0.096 12.9 0.1 0.26 11.4 0.1 1.7 1 0 0 1 1 1 0 DUF2407 C-terminal domain Het-C PF07217.11 KUM58426.1 - 5.4e-247 820.8 0.0 6.8e-247 820.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C ADH_N PF08240.12 KUM58428.1 - 1e-34 118.7 0.8 1.4e-34 118.2 0.1 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM58428.1 - 1.9e-22 79.6 0.2 3e-22 79.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KUM58428.1 - 5.6e-08 32.5 0.3 1e-07 31.7 0.3 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KUM58428.1 - 0.00054 19.6 0.0 0.00092 18.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 KUM58428.1 - 0.0015 19.6 0.0 0.0029 18.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KUM58428.1 - 0.003 16.9 0.5 0.0048 16.2 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KUM58428.1 - 0.0073 15.6 0.1 0.015 14.5 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 KUM58428.1 - 0.033 14.9 0.1 0.075 13.8 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KUM58428.1 - 0.046 13.1 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FtsJ PF01728.19 KUM58428.1 - 0.11 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase FAD-oxidase_C PF02913.19 KUM58429.1 - 4e-54 183.9 0.5 1e-53 182.6 0.4 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KUM58429.1 - 1.4e-36 125.2 0.0 2.9e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Ras PF00071.22 KUM58431.1 - 1.1e-39 135.6 0.0 1.6e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM58431.1 - 5.4e-27 94.4 0.0 8.7e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM58431.1 - 9.1e-11 41.5 0.0 1.1e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KUM58431.1 - 0.0022 17.4 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KUM58431.1 - 0.0038 17.3 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KUM58431.1 - 0.039 13.4 0.0 0.068 12.6 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KUM58431.1 - 0.049 13.5 0.0 0.66 9.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 KUM58431.1 - 0.087 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KUM58431.1 - 0.091 13.1 0.2 0.37 11.2 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KUM58431.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter UCH PF00443.29 KUM58432.1 - 6.2e-40 137.3 0.0 8.9e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KUM58432.1 - 2.2e-24 85.0 1.0 7e-23 80.2 0.1 2.8 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 KUM58432.1 - 2e-23 82.5 13.1 1.8e-18 66.6 2.3 3.5 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 KUM58432.1 - 1.1e-18 66.7 0.8 2e-11 43.5 0.0 3.0 3 0 0 3 3 3 2 UBA/TS-N domain UCH_1 PF13423.6 KUM58432.1 - 4.3e-18 66.0 0.3 1.3e-16 61.1 0.0 2.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase XK-related PF09815.9 KUM58433.1 - 0.013 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 XK-related protein Fer4_13 PF13370.6 KUM58433.1 - 0.37 11.4 5.0 4.9 7.8 0.0 4.1 3 2 1 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I Fn_bind PF02986.14 KUM58433.1 - 3.8 7.3 5.4 14 5.5 0.4 2.5 2 0 0 2 2 2 0 Fibronectin binding repeat Rft-1 PF04506.13 KUM58434.1 - 4.7e-139 464.4 20.6 5.6e-139 464.2 20.6 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 KUM58434.1 - 1.2e-09 38.0 14.7 1.2e-09 38.0 14.7 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DEAD PF00270.29 KUM58435.1 - 2.1e-48 164.4 0.0 4e-48 163.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM58435.1 - 2.2e-31 108.5 0.0 8.5e-29 100.1 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KUM58435.1 - 5.9e-09 36.1 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KUM58435.1 - 0.0033 16.7 0.1 0.0072 15.6 0.0 1.6 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 KUM58435.1 - 0.0033 16.8 0.3 0.14 11.4 0.0 2.7 3 0 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 KUM58435.1 - 0.0079 15.0 0.0 1.5 7.5 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Myc_target_1 PF15179.6 KUM58435.1 - 0.27 11.1 0.6 0.42 10.5 0.6 1.2 1 0 0 1 1 1 0 Myc target protein 1 Rep_fac-A_C PF08646.10 KUM58437.1 - 1.5e-54 183.7 5.3 1.2e-52 177.5 0.5 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KUM58437.1 - 7.1e-37 125.3 0.4 3.9e-36 122.9 0.4 2.2 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 KUM58437.1 - 6e-22 77.6 0.5 1.2e-21 76.6 0.1 1.7 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KUM58437.1 - 2.1e-12 46.8 0.1 1.4e-07 31.4 0.0 3.5 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KUM58437.1 - 0.00041 20.1 0.3 0.0042 16.8 0.0 2.5 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 DUF4503 PF14951.6 KUM58437.1 - 0.076 11.5 0.2 0.12 10.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) OST3_OST6 PF04756.13 KUM58438.1 - 1.1e-35 123.4 0.1 1.8e-35 122.7 0.0 1.4 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KUM58438.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin APG6_N PF17675.1 KUM58439.1 - 0.015 15.8 21.9 0.015 15.8 21.9 3.4 2 1 2 4 4 4 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 KUM58439.1 - 0.098 12.1 37.3 0.34 10.3 19.4 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 Filament PF00038.21 KUM58439.1 - 0.49 9.9 36.7 9.6 5.7 36.1 3.0 1 1 0 1 1 1 0 Intermediate filament protein DUF4600 PF15372.6 KUM58439.1 - 0.55 10.7 21.0 0.078 13.4 13.2 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4600) DUF1081 PF06448.11 KUM58439.1 - 1 9.7 6.3 0.98 9.8 2.7 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1081) DUF3584 PF12128.8 KUM58439.1 - 1.5 6.2 36.1 2.2 5.7 36.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.8 KUM58439.1 - 7.4 6.6 44.4 8 6.5 13.7 4.9 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 KUM58439.1 - 8.4 6.8 43.7 0.044 14.2 26.7 3.5 2 1 1 3 3 3 0 Fez1 Sugar_tr PF00083.24 KUM58441.1 - 9.3e-105 351.1 20.3 1.1e-104 350.8 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM58441.1 - 3.4e-21 75.5 30.7 1.1e-14 54.2 10.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OST3_OST6 PF04756.13 KUM58442.1 - 3.3e-54 184.2 4.8 3.7e-54 184.1 4.8 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TMEM100 PF16311.5 KUM58443.1 - 0.0078 15.8 0.4 0.013 15.1 0.4 1.4 1 0 0 1 1 1 1 Transmembrane protein 100 DUF3616 PF12275.8 KUM58443.1 - 0.0095 15.4 0.8 0.01 15.3 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3616) UPF0542 PF15086.6 KUM58443.1 - 3.9 7.5 9.8 1.1 9.3 4.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Membr_traf_MHD PF10540.9 KUM58444.1 - 6.3e-21 75.1 0.6 1.5e-10 41.4 0.7 3.4 2 1 1 3 3 3 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KUM58444.1 - 8.2e-15 55.0 0.0 2e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain NDUF_B8 PF05821.11 KUM58445.1 - 2.8e-08 33.8 0.6 4e-08 33.3 0.6 1.4 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.23 KUM58446.1 - 1.8e-63 214.4 0.2 3.1e-63 213.6 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KUM58446.1 - 4.2e-19 68.9 0.0 1.4e-18 67.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM58446.1 - 1.8e-10 41.1 0.0 3.8e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 KUM58446.1 - 1.1e-07 32.0 6.8 1.1e-07 32.0 6.8 2.5 2 0 0 2 2 2 1 HSA DEAD PF00270.29 KUM58446.1 - 0.00022 21.0 0.0 0.00051 19.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 KUM58446.1 - 0.024 14.2 0.1 0.077 12.6 0.0 1.8 2 0 0 2 2 2 0 DEAD_2 Glyco_hydro_47 PF01532.20 KUM58448.1 - 5.8e-116 388.1 0.0 7.6e-116 387.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GGACT PF06094.12 KUM58449.1 - 0.00034 21.2 0.0 0.00052 20.6 0.0 1.5 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KUM58449.1 - 0.00035 20.9 0.0 0.0016 18.8 0.0 2.1 2 0 0 2 2 2 1 AIG2-like family Pribosyltran PF00156.27 KUM58450.1 - 5.5e-17 61.7 0.0 7.3e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Thi4 PF01946.17 KUM58450.1 - 0.15 11.3 0.2 0.21 10.8 0.2 1.2 1 0 0 1 1 1 0 Thi4 family AP_endonuc_2 PF01261.24 KUM58451.1 - 2.4e-24 86.0 0.0 4.8e-24 85.0 0.0 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel WD40 PF00400.32 KUM58452.1 - 6.6e-39 131.2 6.5 5.6e-07 30.2 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM58452.1 - 2.5e-11 43.7 0.2 0.033 14.5 0.0 5.1 2 2 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KUM58452.1 - 0.0086 14.9 0.2 1 8.0 0.1 2.6 1 1 2 3 3 3 2 Nup133 N terminal like WD40_like PF17005.5 KUM58452.1 - 0.027 13.8 0.0 5.9 6.1 0.0 3.0 2 1 1 3 3 3 0 WD40-like domain PQQ_2 PF13360.6 KUM58452.1 - 0.1 12.1 1.3 7.6 6.0 0.1 3.0 1 1 2 4 4 4 0 PQQ-like domain MAGUK_N_PEST PF10608.9 KUM58453.1 - 3.2 8.2 8.4 11 6.5 7.2 2.8 1 1 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK Ribonuc_L-PSP PF01042.21 KUM58454.1 - 2.4e-40 137.3 0.2 2.7e-40 137.2 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP TRAPP PF04051.16 KUM58456.1 - 3.5e-31 107.9 0.0 4.2e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 KUM58456.1 - 0.0063 15.4 0.0 0.0072 15.2 0.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF4250 PF14056.6 KUM58456.1 - 0.064 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Sec63 PF02889.16 KUM58457.1 - 2.4e-36 125.2 0.1 3.4e-36 124.7 0.1 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KUM58457.1 - 8.6e-26 90.8 0.1 1.5e-25 90.0 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KUM58457.1 - 2.7e-14 53.5 0.0 5.2e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KUM58457.1 - 2.3e-08 34.4 0.0 1.2e-07 32.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KUM58457.1 - 0.00028 21.2 0.0 0.00078 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KUM58457.1 - 0.00095 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KUM58457.1 - 0.004 17.5 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KUM58457.1 - 0.014 14.9 0.0 0.037 13.6 0.0 1.7 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain HHH_5 PF14520.6 KUM58457.1 - 0.02 15.5 0.0 0.059 14.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain T2SSE PF00437.20 KUM58457.1 - 0.062 12.4 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Acid_PPase PF12689.7 KUM58458.1 - 9.3e-70 233.8 0.0 1.1e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Hexapep PF00132.24 KUM58459.1 - 2.7e-10 39.6 5.1 0.00038 20.1 0.3 3.7 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KUM58459.1 - 0.022 14.5 3.9 0.22 11.3 0.5 2.8 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase TPR_MLP1_2 PF07926.12 KUM58460.1 - 2.3e-36 124.7 27.1 2.3e-36 124.7 27.1 17.3 8 5 9 17 17 17 8 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 KUM58460.1 - 8.7e-05 22.6 18.4 8.7e-05 22.6 18.4 16.4 7 3 8 16 16 16 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 KUM58460.1 - 0.00019 21.3 27.4 0.00019 21.3 27.4 13.8 6 4 4 12 12 12 1 Coiled-coil region of CCDC155 or KASH ParE_toxin PF05016.15 KUM58460.1 - 0.072 13.7 0.1 0.072 13.7 0.1 6.0 5 0 0 5 5 5 0 ParE toxin of type II toxin-antitoxin system, parDE Nuc_sug_transp PF04142.15 KUM58462.1 - 6.7e-86 288.3 1.8 8.6e-86 287.9 1.8 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KUM58462.1 - 2.3e-05 23.8 4.1 0.0002 20.7 4.1 2.0 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 KUM58462.1 - 0.0036 16.7 7.3 0.055 12.8 0.8 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family TMEM234 PF10639.9 KUM58462.1 - 0.011 15.8 1.2 0.011 15.8 1.2 1.9 2 0 0 2 2 2 0 Putative transmembrane family 234 EmrE PF13536.6 KUM58462.1 - 0.015 14.9 0.1 0.015 14.9 0.1 2.9 3 0 0 3 3 3 0 Putative multidrug resistance efflux transporter DUF1689 PF07954.11 KUM58462.1 - 0.16 12.4 0.0 0.44 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) EamA PF00892.20 KUM58462.1 - 1.1 9.4 26.2 0.037 14.2 9.4 2.7 2 1 0 2 2 2 0 EamA-like transporter family Pkinase PF00069.25 KUM58463.1 - 5.9e-59 199.6 0.0 7.7e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM58463.1 - 2.6e-24 85.9 0.0 3.6e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM58463.1 - 9.7e-08 31.7 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KUM58463.1 - 0.0027 17.7 0.1 2.1 8.2 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KUM58463.1 - 0.16 11.3 0.0 0.35 10.2 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 KUM58464.1 - 0.00026 20.8 0.0 0.00055 19.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KUM58464.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain PP28 PF10252.9 KUM58464.1 - 0.18 12.3 3.6 15 6.1 3.2 3.1 3 0 0 3 3 3 0 Casein kinase substrate phosphoprotein PP28 Gag_p12 PF01141.18 KUM58464.1 - 0.18 12.1 2.4 1.1 9.6 0.8 2.9 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 OHCU_decarbox PF09349.10 KUM58464.1 - 0.23 11.9 0.1 0.23 11.9 0.1 1.7 2 0 0 2 2 2 0 OHCU decarboxylase TFA2_Winged_2 PF18121.1 KUM58465.1 - 5.7e-23 80.4 0.2 1.3e-22 79.2 0.2 1.7 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KUM58465.1 - 1.1e-19 70.5 0.1 5.4e-19 68.2 0.0 2.2 2 1 0 2 2 2 1 TFIIE beta subunit core domain DUF3446 PF11928.8 KUM58465.1 - 0.095 13.0 2.8 0.19 12.1 2.8 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain DHBP_synthase PF00926.19 KUM58466.1 - 3e-80 268.3 0.0 3.5e-80 268.1 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase AA_permease_2 PF13520.6 KUM58467.1 - 8.1e-65 219.3 45.3 1e-64 219.0 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM58467.1 - 2.3e-23 82.6 35.9 3.3e-23 82.0 35.9 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 KUM58467.1 - 0.022 14.7 0.0 0.022 14.7 0.0 3.5 3 0 0 3 3 3 0 LPXTG cell wall anchor motif DPM3 PF08285.11 KUM58467.1 - 0.17 12.1 0.0 0.17 12.1 0.0 4.0 4 2 1 5 5 5 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF5317 PF17248.2 KUM58467.1 - 5 7.1 14.6 3.3 7.7 2.9 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5317) TetR_C_10 PF16295.5 KUM58468.1 - 0.049 13.9 0.0 0.058 13.7 0.0 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Rad10 PF03834.14 KUM58468.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Transferase PF02458.15 KUM58469.1 - 1.8e-20 73.0 0.0 3.4e-19 68.8 0.0 2.1 2 0 0 2 2 2 2 Transferase family UPRTase PF14681.6 KUM58470.1 - 0.18 11.2 0.5 0.32 10.4 0.5 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase NuA4 PF09340.10 KUM58471.1 - 8.5e-28 96.0 0.4 8.5e-28 96.0 0.4 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Glyco_hydro_38N PF01074.22 KUM58472.1 - 3.7e-88 295.6 2.3 3.7e-88 295.6 2.3 2.6 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KUM58472.1 - 3.8e-60 203.6 0.1 4.7e-59 200.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KUM58472.1 - 1e-27 96.1 0.0 2.3e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KUM58472.1 - 6.9e-10 38.9 0.0 1.6e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 KUM58472.1 - 0.076 12.2 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Ctr PF04145.15 KUM58473.1 - 3.6e-31 108.8 0.9 4.5e-31 108.5 0.9 1.1 1 0 0 1 1 1 1 Ctr copper transporter family CPBP PF02517.16 KUM58473.1 - 0.052 13.9 3.2 6.2 7.3 0.4 2.3 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease MBOAT_2 PF13813.6 KUM58474.1 - 1.5e-22 79.7 1.5 2.8e-22 78.8 1.5 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF3789 PF12664.7 KUM58474.1 - 0.26 11.0 2.4 0.52 10.1 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) EMC3_TMCO1 PF01956.16 KUM58474.1 - 4.4 7.0 6.8 1.3 8.7 0.6 2.4 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Amino_oxidase PF01593.24 KUM58475.1 - 3.4e-29 102.4 0.0 1.4e-27 97.1 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KUM58475.1 - 2.4e-10 40.5 0.0 9.7e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KUM58475.1 - 0.046 13.0 0.1 0.077 12.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KUM58475.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KUM58477.1 - 3.4e-24 85.5 17.1 4.9e-24 84.9 17.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KUM58477.1 - 2.6e-08 33.6 3.8 2.6e-08 33.6 3.8 1.8 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KUM58477.1 - 3.7e-06 25.6 3.8 4.5e-06 25.4 3.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM58477.1 - 4.2e-05 22.6 13.6 0.00033 19.6 13.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Prok-E2_D PF14460.6 KUM58478.1 - 0.068 12.8 0.0 0.082 12.6 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family D DLP_helical PF18709.1 KUM58478.1 - 0.17 11.1 0.0 0.18 11.0 0.0 1.0 1 0 0 1 1 1 0 Dynamin-like helical domain FAA_hydrolase PF01557.18 KUM58480.1 - 6.6e-49 166.5 0.0 5.4e-31 108.0 0.0 2.0 2 0 0 2 2 2 2 Fumarylacetoacetate (FAA) hydrolase family DEAD PF00270.29 KUM58481.1 - 2.7e-44 151.0 0.8 5e-44 150.1 0.8 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM58481.1 - 1.6e-31 108.9 0.1 1.2e-30 106.1 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM58481.1 - 3.2e-05 24.0 0.0 5.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KUM58481.1 - 0.00021 21.1 0.1 0.0004 20.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KUM58481.1 - 0.00083 19.7 0.6 0.0048 17.2 0.4 2.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KUM58481.1 - 0.005 17.1 0.5 0.028 14.7 0.5 2.2 1 1 0 1 1 1 1 AAA domain IL17R_D_N PF16742.5 KUM58481.1 - 0.045 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D CMS1 PF14617.6 KUM58481.1 - 0.068 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Cupin_8 PF13621.6 KUM58482.1 - 9.4e-15 55.0 0.0 4e-13 49.7 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KUM58482.1 - 1.7e-10 41.3 0.1 1.4e-09 38.4 0.1 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 KUM58482.1 - 1.6e-07 31.1 0.0 3.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KUM58482.1 - 0.0057 16.5 0.0 0.016 15.0 0.0 1.9 1 0 0 1 1 1 1 F-box domain SLT PF01464.20 KUM58483.1 - 0.00018 21.2 0.4 0.00073 19.2 0.4 2.1 1 1 0 1 1 1 1 Transglycosylase SLT domain LysM PF01476.20 KUM58483.1 - 0.0029 17.6 0.0 0.012 15.6 0.0 2.1 2 0 0 2 2 2 1 LysM domain F-box-like PF12937.7 KUM58484.1 - 8.8e-05 22.3 0.8 0.00023 21.0 0.8 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KUM58484.1 - 0.00027 20.7 0.2 0.00073 19.3 0.2 1.8 1 0 0 1 1 1 1 F-box domain Pyr_redox_2 PF07992.14 KUM58485.1 - 2.3e-51 174.8 0.0 3e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM58485.1 - 4.5e-10 39.9 0.0 1.6e-08 34.9 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM58485.1 - 0.0014 17.9 0.0 0.77 9.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Arrestin_C PF02752.22 KUM58486.1 - 9.7e-16 58.4 0.0 8.7e-15 55.4 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KUM58486.1 - 2.1e-08 34.3 0.0 0.00031 20.8 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KUM58486.1 - 0.0032 17.2 0.0 0.064 13.0 0.0 2.3 2 0 0 2 2 2 1 Arrestin_N terminal like Dynamin_N PF00350.23 KUM58487.1 - 9.7e-46 155.9 0.0 1.8e-45 155.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KUM58487.1 - 6.2e-14 51.9 0.0 2.2e-11 43.5 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KUM58487.1 - 1.6e-05 24.9 0.0 0.00018 21.6 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KUM58487.1 - 0.0089 16.4 0.7 0.17 12.3 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain Se-cys_synth_N PF12390.8 KUM58487.1 - 0.049 13.9 0.0 0.19 12.0 0.0 2.1 1 0 0 1 1 1 0 Selenocysteine synthase N terminal AAA_21 PF13304.6 KUM58487.1 - 0.066 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KUM58487.1 - 0.078 12.7 0.4 0.26 10.9 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KUM58487.1 - 0.083 13.1 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KUM58487.1 - 0.14 12.4 0.0 0.43 10.8 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GATase_4 PF13230.6 KUM58488.1 - 4.4e-12 45.5 0.0 5e-11 42.0 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KUM58488.1 - 7.6e-08 32.6 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain BORG_CEP PF14957.6 KUM58491.1 - 0.034 15.3 2.5 0.049 14.8 2.5 1.2 1 0 0 1 1 1 0 Cdc42 effector Acetyltransf_10 PF13673.7 KUM58492.1 - 1.3e-12 47.8 0.0 2.2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM58492.1 - 2e-10 41.0 0.0 3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KUM58492.1 - 1.4e-09 38.2 0.0 2.1e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KUM58492.1 - 1.4e-05 25.2 0.0 0.015 15.4 0.0 3.0 2 1 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KUM58492.1 - 0.0015 18.7 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KUM58492.1 - 0.0015 18.5 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Abhydrolase_6 PF12697.7 KUM58493.1 - 2.2e-06 28.4 1.8 3.1e-06 27.9 1.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KUM58493.1 - 3.2e-06 26.8 0.0 5.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KUM58493.1 - 0.00016 21.5 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KUM58493.1 - 0.00048 19.5 0.0 0.00089 18.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 KUM58493.1 - 0.0085 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 KUM58493.1 - 0.013 15.0 0.1 0.085 12.3 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_8 PF06259.12 KUM58493.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_3 PF07859.13 KUM58493.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chs7 PF12271.8 KUM58494.1 - 6.7e-123 409.6 15.0 7.7e-123 409.4 15.0 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 KUM58494.1 - 0.0039 17.4 5.8 0.0073 16.6 3.2 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF3382) DUF2873 PF11395.8 KUM58494.1 - 8.4 6.3 8.4 5.7 6.9 0.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) DUF3147 PF11345.8 KUM58494.1 - 9.4 6.6 12.4 4.8 7.6 1.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3147) Ank_2 PF12796.7 KUM58495.1 - 9.8e-48 160.7 10.4 1.9e-12 47.6 0.1 9.7 6 3 4 10 10 10 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM58495.1 - 2.2e-36 123.7 8.5 1.3e-05 25.6 0.0 11.6 8 4 6 14 14 14 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM58495.1 - 1.8e-29 98.5 12.5 0.094 13.3 0.0 16.5 19 0 0 19 19 19 6 Ankyrin repeat Ank_5 PF13857.6 KUM58495.1 - 1.3e-19 70.0 16.9 0.0014 18.8 0.1 11.9 9 4 5 14 14 14 6 Ankyrin repeats (many copies) Ank PF00023.30 KUM58495.1 - 1e-10 41.5 28.1 1.4 9.5 0.1 13.3 16 1 0 16 16 16 4 Ankyrin repeat PKS_DE PF18369.1 KUM58495.1 - 0.0016 19.0 0.2 2.2 8.9 0.0 2.8 2 0 0 2 2 2 2 Polyketide synthase dimerisation element domain Isochorismatase PF00857.20 KUM58496.1 - 2.6e-15 57.0 0.2 6.1e-15 55.8 0.2 1.6 1 1 0 1 1 1 1 Isochorismatase family Fungal_trans PF04082.18 KUM58497.1 - 4.2e-21 75.2 0.0 1.4e-20 73.5 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM58497.1 - 1.7e-05 24.9 14.8 3.7e-05 23.8 14.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tmemb_cc2 PF10267.9 KUM58497.1 - 0.017 14.3 0.5 0.031 13.4 0.5 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein PAC4 PF16093.5 KUM58498.1 - 1.7e-26 92.2 0.1 2.4e-26 91.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Prefoldin_2 PF01920.20 KUM58499.1 - 5.6e-24 84.1 4.4 7.1e-24 83.8 4.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit GPS2_interact PF15784.5 KUM58499.1 - 0.033 14.6 5.7 0.13 12.8 0.0 2.2 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain DUF3338 PF11819.8 KUM58499.1 - 0.083 12.9 4.6 1.9 8.4 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) DUF5065 PF16723.5 KUM58499.1 - 0.11 12.6 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) DivIC PF04977.15 KUM58499.1 - 0.34 10.7 9.0 2.6 7.9 4.9 2.2 2 0 0 2 2 2 0 Septum formation initiator ATG27 PF09451.10 KUM58500.1 - 1.3e-90 303.8 0.0 1.5e-90 303.6 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KUM58500.1 - 5.4e-06 26.5 0.0 0.0045 17.1 0.0 2.6 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat PD40 PF07676.12 KUM58501.1 - 1.5e-48 161.8 24.9 5.6e-09 35.7 0.2 9.5 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 KUM58501.1 - 3.5e-09 35.9 8.6 0.0037 16.1 1.6 6.5 3 2 1 5 5 5 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF5050 PF16472.5 KUM58501.1 - 1.1e-07 31.4 0.3 0.00048 19.5 0.0 4.1 4 1 1 5 5 5 2 Domain of unknown function (DUF5050) DUF3748 PF12566.8 KUM58501.1 - 8e-05 22.6 0.5 6.2 6.8 0.0 4.8 4 1 0 4 4 4 2 Protein of unknown function (DUF3748) WD40 PF00400.32 KUM58501.1 - 0.018 15.9 8.9 12 7.0 0.1 5.8 7 1 0 7 7 7 0 WD domain, G-beta repeat Proteasome_A_N PF10584.9 KUM58501.1 - 0.22 11.2 5.1 18 5.1 0.1 5.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature N2227 PF07942.12 KUM58502.1 - 2.9e-91 305.4 0.0 3.6e-91 305.1 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 KUM58502.1 - 0.0021 18.8 0.0 0.024 15.4 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM58502.1 - 0.0049 17.5 0.0 0.014 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM58502.1 - 0.01 15.7 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KUM58502.1 - 0.12 13.0 0.0 0.37 11.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KUM58502.1 - 0.15 11.8 0.0 0.73 9.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain HSP70 PF00012.20 KUM58505.1 - 1.2e-10 40.3 0.4 2.7e-09 35.8 0.2 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KUM58505.1 - 0.039 12.8 0.2 0.29 9.9 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein Chromate_transp PF02417.15 KUM58506.1 - 6.8e-38 130.3 34.0 6e-33 114.2 14.7 2.3 2 0 0 2 2 2 2 Chromate transporter DAD PF02109.16 KUM58506.1 - 1.6 9.0 4.2 2.9 8.2 0.1 3.0 3 0 0 3 3 3 0 DAD family AAA_2 PF07724.14 KUM58507.1 - 1.9e-46 158.3 0.0 3.9e-45 154.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KUM58507.1 - 1.6e-33 114.7 1.7 1.6e-33 114.7 1.7 3.1 3 0 0 3 3 3 1 AAA lid domain AAA PF00004.29 KUM58507.1 - 4.3e-27 95.1 0.0 1.4e-14 54.6 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KUM58507.1 - 1.8e-24 85.6 0.2 5.5e-24 84.0 0.2 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KUM58507.1 - 6.1e-15 55.4 0.0 4.7e-09 36.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KUM58507.1 - 3.4e-13 50.3 4.3 9.3e-07 29.4 0.0 5.0 4 1 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 KUM58507.1 - 5.8e-13 49.3 0.0 8.8e-05 22.8 0.0 4.3 2 1 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 KUM58507.1 - 1.3e-08 34.8 0.0 4.8e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 KUM58507.1 - 1.5e-06 28.1 0.0 0.11 12.2 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.6 KUM58507.1 - 2.1e-06 27.8 0.0 0.053 13.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KUM58507.1 - 2.6e-06 28.0 0.0 0.064 13.8 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 KUM58507.1 - 3.3e-06 26.7 0.0 0.014 14.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 KUM58507.1 - 6.1e-06 26.3 0.2 0.11 12.3 0.3 4.1 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea TniB PF05621.11 KUM58507.1 - 6.5e-06 25.7 0.2 0.071 12.5 0.0 4.5 4 1 0 4 4 4 1 Bacterial TniB protein Mg_chelatase PF01078.21 KUM58507.1 - 1.3e-05 24.7 0.0 0.19 11.1 0.0 3.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KUM58507.1 - 2e-05 24.8 0.1 0.26 11.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KUM58507.1 - 5.1e-05 23.6 0.4 0.61 10.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KUM58507.1 - 7.1e-05 23.2 0.0 0.56 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 KUM58507.1 - 0.00021 21.1 0.0 1.3 8.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.12 KUM58507.1 - 0.00028 20.7 1.1 3.1 7.5 0.9 4.2 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 KUM58507.1 - 0.00031 21.3 1.0 0.93 10.0 0.0 3.4 3 0 0 3 3 3 1 ABC transporter TsaE PF02367.17 KUM58507.1 - 0.00037 20.5 0.0 0.33 11.0 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KUM58507.1 - 0.00048 20.0 0.0 1.5 8.7 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KUM58507.1 - 0.00052 20.0 0.2 0.59 10.0 0.0 2.9 3 0 0 3 3 2 1 RsgA GTPase AAA_24 PF13479.6 KUM58507.1 - 0.00077 19.2 0.0 0.71 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 KUM58507.1 - 0.00096 18.3 0.8 0.0081 15.3 0.2 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 KUM58507.1 - 0.0012 18.6 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.6 KUM58507.1 - 0.0023 18.3 0.0 0.59 10.5 0.1 3.1 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 KUM58507.1 - 0.0034 17.6 0.0 1 9.6 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KUM58507.1 - 0.0052 17.3 10.0 0.21 12.1 0.0 4.1 4 1 0 4 4 4 1 AAA domain AAA_25 PF13481.6 KUM58507.1 - 0.0063 16.1 0.1 0.9 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KUM58507.1 - 0.0073 16.2 0.0 0.5 10.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.15 KUM58507.1 - 0.011 15.7 0.0 0.3 11.0 0.0 2.9 3 0 0 3 3 3 0 NTPase Clp_N PF02861.20 KUM58507.1 - 0.017 15.2 0.2 3.3 7.9 0.0 3.5 3 0 0 3 3 3 0 Clp amino terminal domain, pathogenicity island component SRP54 PF00448.22 KUM58507.1 - 0.02 14.6 0.1 7.9 6.1 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Torsin PF06309.11 KUM58507.1 - 0.074 13.2 0.0 0.36 10.9 0.0 2.0 2 0 0 2 2 1 0 Torsin ResIII PF04851.15 KUM58507.1 - 0.084 12.9 0.0 13 5.7 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Rad17 PF03215.15 KUM58507.1 - 0.088 12.7 0.0 14 5.6 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain Rossmann-like PF10727.9 KUM58507.1 - 0.16 11.8 0.3 11 5.8 0.0 2.6 2 0 0 2 2 2 0 Rossmann-like domain V_ATPase_I PF01496.19 KUM58507.1 - 1.3 6.9 3.7 1.8 6.4 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 KUM58507.1 - 3.1 6.2 7.4 4.5 5.7 7.4 1.2 1 0 0 1 1 1 0 Macoilin family Sulfotransfer_3 PF13469.6 KUM58508.1 - 0.01 16.2 0.6 1.6 9.1 0.0 3.1 3 1 0 3 3 3 0 Sulfotransferase family NCOA_u2 PF16665.5 KUM58509.1 - 0.063 13.6 0.3 0.082 13.2 0.3 1.1 1 0 0 1 1 1 0 Unstructured region on nuclear receptor coactivator protein DUF676 PF05057.14 KUM58510.1 - 7.9e-48 162.9 0.0 1.2e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KUM58510.1 - 3.8e-05 23.6 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 KUM58510.1 - 3.9e-05 23.6 0.0 6.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KUM58510.1 - 7.8e-05 23.4 0.0 0.00011 22.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KUM58510.1 - 0.00021 21.1 0.0 0.001 18.9 0.0 2.0 2 1 0 2 2 2 1 PGAP1-like protein DUF2235 PF09994.9 KUM58510.1 - 0.027 13.9 0.0 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Lipase_2 PF01674.18 KUM58510.1 - 0.033 13.7 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_2 PF02230.16 KUM58510.1 - 0.044 13.6 0.1 1.1 9.0 0.1 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase LCAT PF02450.15 KUM58510.1 - 0.051 12.7 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DLH PF01738.18 KUM58510.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family tRNA-synt_2c PF01411.19 KUM58511.1 - 1.9e-10 39.9 0.0 2.5e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KUM58511.1 - 4.4e-08 33.1 1.0 8.2e-08 32.2 1.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Ribosomal_L22e PF01776.17 KUM58512.1 - 7.9e-48 161.4 0.4 9.7e-48 161.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family NAM-associated PF14303.6 KUM58513.1 - 0.19 12.5 4.1 0.39 11.4 4.1 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SOG2 PF10428.9 KUM58513.1 - 0.34 10.1 10.4 0.51 9.5 10.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein CFEM PF05730.11 KUM58514.1 - 0.00026 21.0 7.6 0.00053 20.0 7.6 1.5 1 0 0 1 1 1 1 CFEM domain Apt1 PF10351.9 KUM58514.1 - 0.011 14.7 3.5 0.02 13.7 3.5 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KUM58514.1 - 0.21 10.1 5.1 0.32 9.5 5.1 1.2 1 0 0 1 1 1 0 Macoilin family DUF2981 PF11200.8 KUM58514.1 - 7.3 6.2 7.4 15 5.2 7.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Hydrolase_6 PF13344.6 KUM58516.1 - 2.1e-21 75.9 0.0 4.2e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KUM58516.1 - 3.8e-12 46.1 0.0 2.6e-11 43.4 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KUM58516.1 - 0.014 15.7 0.0 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Lipase_3 PF01764.25 KUM58516.1 - 0.034 14.0 0.0 0.094 12.6 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) F-box-like PF12937.7 KUM58517.1 - 0.06 13.2 0.2 0.19 11.6 0.2 1.8 1 0 0 1 1 1 0 F-box-like VEFS-Box PF09733.9 KUM58517.1 - 0.14 12.0 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 VEFS-Box of polycomb protein DIM1 PF02966.16 KUM58518.1 - 5.4e-70 233.3 0.3 6.1e-70 233.2 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KUM58518.1 - 0.05 13.6 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF3192 PF11399.8 KUM58518.1 - 0.053 13.5 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) G-alpha PF00503.20 KUM58519.1 - 5.3e-108 361.3 0.3 6.1e-108 361.1 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KUM58519.1 - 4.5e-14 52.3 0.1 2.7e-09 36.7 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KUM58519.1 - 1.3e-06 28.0 0.2 0.0013 18.1 0.1 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KUM58519.1 - 0.0018 18.3 0.0 2.3 8.3 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase Roc PF08477.13 KUM58519.1 - 0.0039 17.4 0.0 0.86 9.8 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF1967 PF09269.11 KUM58519.1 - 0.012 15.6 0.1 19 5.3 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) GTP_EFTU PF00009.27 KUM58519.1 - 0.062 12.8 0.0 4.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 KUM58519.1 - 0.069 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 KUM58519.1 - 0.098 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 KUM58519.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Translin PF01997.16 KUM58520.1 - 4.4e-49 167.2 0.0 5.1e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Translin family FRQ PF09421.10 KUM58520.1 - 0.049 11.7 0.2 0.064 11.3 0.2 1.1 1 0 0 1 1 1 0 Frequency clock protein GMP_synt_C PF00958.22 KUM58520.1 - 0.057 13.5 0.0 0.5 10.4 0.0 2.2 2 0 0 2 2 2 0 GMP synthase C terminal domain DUF5631 PF18645.1 KUM58520.1 - 0.075 13.4 0.3 0.25 11.8 0.3 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5631) Rx_N PF18052.1 KUM58520.1 - 0.34 11.2 2.3 12 6.2 0.6 3.1 2 1 0 2 2 2 0 Rx N-terminal domain GSHPx PF00255.19 KUM58521.1 - 1.3e-37 127.6 0.0 1.9e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KUM58521.1 - 0.025 14.5 0.0 0.038 13.9 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA family Ral PF11058.8 KUM58521.1 - 0.079 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral DSPn PF14671.6 KUM58523.1 - 2.2e-43 148.1 0.0 6.9e-41 140.0 0.0 2.9 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KUM58523.1 - 7.8e-17 61.3 0.0 6e-16 58.5 0.0 2.3 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KUM58523.1 - 1.7e-05 24.5 0.1 4.4e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DUF1713 PF08213.11 KUM58524.1 - 6.8e-12 45.1 20.1 1.4e-11 44.1 20.1 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) DUF1180 PF06679.12 KUM58524.1 - 0.62 10.5 6.8 1.2 9.5 3.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) SR-25 PF10500.9 KUM58524.1 - 9.6 5.7 23.2 1.8 8.1 1.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ATP-synt_C PF00137.21 KUM58525.1 - 9.4e-36 122.0 32.2 6.1e-22 77.7 14.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.8 KUM58525.1 - 0.58 10.1 9.0 0.22 11.4 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) SH PF01445.17 KUM58525.1 - 3.9 7.5 4.6 5.3 7.1 0.2 2.6 3 0 0 3 3 3 0 Viral small hydrophobic protein Kinesin PF00225.23 KUM58526.1 - 3.6e-96 322.0 0.0 7e-96 321.0 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KUM58526.1 - 1.6e-24 86.5 0.0 4e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Lebercilin PF15619.6 KUM58526.1 - 0.0043 16.8 0.2 0.0043 16.8 0.2 2.4 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease PKcGMP_CC PF16808.5 KUM58526.1 - 0.037 13.9 3.5 0.16 11.9 0.5 3.0 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 KUM58526.1 - 1.3 8.3 12.6 2.2 7.6 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Lzipper-MIP1 PF14389.6 KUM58526.1 - 1.5 9.2 9.2 6.7 7.1 0.0 3.7 3 1 1 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 Fib_alpha PF08702.10 KUM58526.1 - 5.6 7.1 6.3 7.8 6.7 0.1 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FAM76 PF16046.5 KUM58526.1 - 9 5.6 8.3 13 5.0 0.1 2.8 1 1 1 3 3 3 0 FAM76 protein IGR PF09597.10 KUM58527.1 - 6e-23 80.7 0.5 1e-22 80.0 0.5 1.4 1 0 0 1 1 1 1 IGR protein motif Pkinase PF00069.25 KUM58529.1 - 2.9e-62 210.4 0.0 3.4e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM58529.1 - 8.5e-33 113.7 0.0 1.2e-32 113.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM58529.1 - 0.0069 15.7 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KUM58529.1 - 0.045 13.7 0.1 0.2 11.6 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Asp-B-Hydro_N PF05279.11 KUM58530.1 - 4.5 7.3 10.7 6.8 6.7 10.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Adaptin_N PF01602.20 KUM58531.1 - 1.2e-75 255.1 0.0 1.7e-74 251.3 0.0 2.0 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KUM58531.1 - 1.8e-08 34.6 0.0 1.8e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KUM58531.1 - 3.2e-06 27.5 5.3 0.16 12.4 0.0 3.8 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 KUM58531.1 - 6.9e-05 22.8 1.9 0.57 10.6 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KUM58531.1 - 0.066 13.7 6.9 16 6.1 0.2 4.6 3 1 1 4 4 4 0 HEAT-like repeat Fcf2 PF08698.11 KUM58531.1 - 0.11 12.9 2.8 0.26 11.7 2.8 1.6 1 0 0 1 1 1 0 Fcf2 pre-rRNA processing TPR_14 PF13428.6 KUM58532.1 - 4.8e-08 33.2 0.3 0.078 13.8 0.1 4.6 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KUM58532.1 - 1.8e-06 28.4 2.2 0.0013 19.2 0.1 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KUM58532.1 - 2.1e-06 27.3 0.0 0.24 11.1 0.0 4.0 4 0 0 4 4 4 2 TPR repeat TPR_17 PF13431.6 KUM58532.1 - 2.8e-06 27.3 0.2 0.069 13.6 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KUM58532.1 - 7e-06 25.6 0.2 0.00025 20.7 0.1 3.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KUM58532.1 - 1.8e-05 24.5 1.3 0.0037 17.3 0.1 4.7 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KUM58532.1 - 0.00024 21.1 0.7 0.0014 18.6 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KUM58532.1 - 0.0018 18.3 0.2 0.0064 16.6 0.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KUM58532.1 - 0.29 11.5 4.9 3.4 8.0 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KUM58532.1 - 0.55 10.4 5.2 2.8 8.2 0.1 4.5 7 0 0 7 7 7 0 Tetratricopeptide repeat Syja_N PF02383.18 KUM58533.1 - 5.7e-73 246.0 0.0 7.6e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 KUM58533.1 - 4.6e-11 42.7 0.1 8.4e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RAMP4 PF06624.12 KUM58534.1 - 2.3e-23 82.0 0.0 2.6e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DAGAT PF03982.13 KUM58535.1 - 6e-90 301.2 0.0 7.2e-90 300.9 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.13 KUM58535.1 - 2.5 7.8 7.0 1.4 8.7 4.1 1.9 1 1 1 2 2 2 0 Rer1 family G-patch PF01585.23 KUM58536.1 - 7.7e-06 25.7 0.1 0.00012 21.9 0.1 2.5 1 1 0 1 1 1 1 G-patch domain SAPS PF04499.15 KUM58536.1 - 0.086 11.6 10.0 0.1 11.4 10.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIF_alpha PF05793.12 KUM58536.1 - 0.29 9.7 34.4 0.36 9.4 34.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4551 PF15087.6 KUM58536.1 - 0.64 8.8 10.3 0.66 8.7 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4746 PF15928.5 KUM58536.1 - 0.66 9.3 11.6 0.9 8.9 11.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Menin PF05053.13 KUM58536.1 - 0.81 8.0 8.7 0.95 7.7 8.7 1.2 1 0 0 1 1 1 0 Menin RR_TM4-6 PF06459.12 KUM58536.1 - 0.91 9.3 18.2 1.5 8.5 18.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3807 PF12720.7 KUM58536.1 - 1.9 8.8 23.7 4.2 7.6 23.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) GREB1 PF15782.5 KUM58536.1 - 2 5.5 13.6 2.2 5.3 13.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Apt1 PF10351.9 KUM58536.1 - 3.5 6.4 24.3 4.6 6.0 24.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 KUM58536.1 - 3.6 5.8 24.1 4.7 5.4 24.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 KUM58536.1 - 4.5 5.7 21.5 5.8 5.3 21.5 1.1 1 0 0 1 1 1 0 Macoilin family Smg8_Smg9 PF10220.9 KUM58536.1 - 7.8 4.7 15.0 9.6 4.4 15.0 1.1 1 0 0 1 1 1 0 Smg8_Smg9 PI3_PI4_kinase PF00454.27 KUM58537.1 - 4.1e-39 134.9 0.0 7.2e-28 98.1 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KUM58537.1 - 4.2e-25 88.2 0.0 1e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 KUM58537.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Sugar_tr PF00083.24 KUM58538.1 - 3.2e-138 461.4 25.7 3.8e-138 461.1 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM58538.1 - 3e-26 92.2 48.3 1.1e-20 73.9 24.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KUM58538.1 - 1.5e-08 33.6 20.1 4.8e-05 22.1 4.3 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein Pox_A14 PF05767.12 KUM58538.1 - 0.012 15.7 0.2 1.1 9.4 0.0 3.0 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 p450 PF00067.22 KUM58539.1 - 9.7e-76 255.4 0.0 1.2e-75 255.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KUM58540.1 - 2.7e-75 253.1 0.0 3.5e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM58540.1 - 2.5e-36 125.3 0.0 3.5e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KUM58540.1 - 8.8e-14 51.6 0.0 1.8e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KUM58540.1 - 5.8e-10 39.0 0.0 7.2e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KUM58540.1 - 4.8e-07 28.9 0.1 5.9e-06 25.3 0.0 2.4 3 0 0 3 3 3 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 KUM58540.1 - 8.6e-05 22.8 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 KUM58540.1 - 0.0007 19.6 0.2 0.0023 17.9 0.2 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KUM58540.1 - 0.0034 17.0 0.0 0.65 9.6 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KUM58540.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KUM58540.1 - 0.077 12.5 0.1 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL ABC_tran PF00005.27 KUM58541.1 - 2.7e-36 125.1 0.0 5.3e-18 65.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KUM58541.1 - 1.7e-28 100.1 29.4 3.6e-23 82.6 13.1 3.4 2 1 1 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.6 KUM58541.1 - 3.2e-10 40.3 3.1 0.078 12.8 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KUM58541.1 - 8.7e-10 38.4 0.2 0.0052 16.2 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 KUM58541.1 - 2e-08 33.6 0.2 0.0036 16.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 KUM58541.1 - 8.9e-07 29.4 1.1 0.047 14.1 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KUM58541.1 - 3.5e-06 26.6 2.1 0.0024 17.6 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KUM58541.1 - 3.6e-06 27.3 1.8 0.26 11.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 KUM58541.1 - 0.00016 21.3 1.2 0.22 11.1 0.1 2.7 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 KUM58541.1 - 0.00037 19.9 0.4 0.037 13.4 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.6 KUM58541.1 - 0.00049 20.3 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KUM58541.1 - 0.0006 19.8 0.2 0.47 10.3 0.1 3.2 3 0 0 3 3 3 1 RsgA GTPase TrwB_AAD_bind PF10412.9 KUM58541.1 - 0.00085 18.3 0.2 0.099 11.5 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 KUM58541.1 - 0.0009 18.8 0.1 0.15 11.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 KUM58541.1 - 0.0012 18.8 3.9 0.19 11.7 0.2 3.2 4 0 0 4 4 2 1 NACHT domain DUF87 PF01935.17 KUM58541.1 - 0.0012 19.0 0.5 0.0094 16.1 0.1 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain Zeta_toxin PF06414.12 KUM58541.1 - 0.0014 17.9 0.4 0.49 9.7 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin DEAD PF00270.29 KUM58541.1 - 0.0023 17.7 0.1 3 7.6 0.0 3.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase CbiA PF01656.23 KUM58541.1 - 0.0023 18.0 0.0 1.5 8.9 0.0 3.3 3 1 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain SbcCD_C PF13558.6 KUM58541.1 - 0.0024 18.1 0.6 3.3 8.0 0.0 3.6 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KUM58541.1 - 0.0047 17.0 0.2 0.38 10.9 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 KUM58541.1 - 0.0048 16.5 1.5 1.8 8.1 0.1 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DnaB_C PF03796.15 KUM58541.1 - 0.012 14.9 0.2 1 8.6 0.0 2.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 KUM58541.1 - 0.019 14.4 1.0 1.6 8.0 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 KUM58541.1 - 0.028 14.2 0.2 4.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 KUM58541.1 - 0.028 14.1 0.3 3.7 7.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KUM58541.1 - 0.035 14.6 0.1 4.8 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KUM58541.1 - 0.04 13.9 1.4 1.3 9.0 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KUM58541.1 - 0.042 13.0 0.4 9.7 5.3 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.16 KUM58541.1 - 0.043 13.3 0.1 4.4 6.7 0.0 2.9 3 0 0 3 3 3 0 PhoH-like protein IstB_IS21 PF01695.17 KUM58541.1 - 0.045 13.5 0.1 13 5.5 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein PduV-EutP PF10662.9 KUM58541.1 - 0.048 13.4 3.4 2 8.2 0.4 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KUM58541.1 - 0.063 13.3 0.1 4.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 KUM58541.1 - 0.076 13.0 0.0 9.6 6.2 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.29 KUM58541.1 - 0.092 13.2 0.6 8.7 6.8 0.1 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KUM58541.1 - 0.11 12.9 0.3 13 6.2 0.0 3.0 3 0 0 3 3 2 0 RNA helicase MobB PF03205.14 KUM58541.1 - 0.13 12.1 1.0 26 4.7 0.1 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 KUM58541.1 - 0.19 12.3 0.6 32 5.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KUM58541.1 - 0.19 11.7 0.9 13 5.8 0.1 2.3 2 0 0 2 2 2 0 Dynamin family DUF2075 PF09848.9 KUM58541.1 - 0.23 10.7 1.1 12 5.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CLP1_P PF16575.5 KUM58541.1 - 0.24 11.2 0.4 2 8.2 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 KUM58541.1 - 0.27 10.9 0.8 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KUM58541.1 - 0.55 10.1 2.7 7.1 6.5 0.1 2.5 2 0 0 2 2 2 0 NTPase MFS_1 PF07690.16 KUM58542.1 - 2.1e-36 125.6 36.7 2.1e-36 125.6 36.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM58542.1 - 2.7e-16 59.5 8.1 2.7e-16 59.5 8.1 2.8 2 2 1 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 KUM58542.1 - 4.4e-05 23.0 1.1 4.4e-05 23.0 1.1 2.4 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB Colicin_im PF03857.13 KUM58542.1 - 0.19 11.7 3.1 6.1 6.8 0.5 2.5 2 0 0 2 2 2 0 Colicin immunity protein OATP PF03137.20 KUM58542.1 - 4.5 5.4 14.9 0.33 9.2 2.3 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Flavin_Reduct PF01613.18 KUM58546.1 - 9.5e-18 64.7 0.0 1.4e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Fungal_trans PF04082.18 KUM58547.1 - 1.3e-19 70.3 0.0 3.7e-18 65.5 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain PAP_central PF04928.17 KUM58549.1 - 2.9e-94 314.7 0.0 4.4e-94 314.1 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KUM58549.1 - 2e-60 203.3 0.0 2.9e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain Nrap_D2 PF17403.2 KUM58549.1 - 0.082 12.7 0.6 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 Nrap protein PAP/OAS-like domain PAP_central PF04928.17 KUM58550.1 - 2.7e-06 26.6 0.0 3.5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain Abhydrolase_1 PF00561.20 KUM58551.1 - 3.2e-13 49.9 0.0 1.3e-11 44.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM58551.1 - 0.00081 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KUM58551.1 - 0.019 15.6 0.0 0.031 14.9 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KUM58551.1 - 0.098 12.1 0.0 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Alpha-amylase PF00128.24 KUM58552.1 - 2.3e-17 63.6 0.4 1.3e-15 57.9 0.4 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KUM58552.1 - 0.013 13.7 0.2 0.23 9.6 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 DUF3632 PF12311.8 KUM58553.1 - 6.4e-38 130.9 0.6 8e-38 130.6 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Mito_carr PF00153.27 KUM58554.1 - 3e-45 152.1 7.7 1.2e-16 60.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pro_racemase PF05544.11 KUM58555.1 - 1.2e-57 195.5 0.1 2.8e-56 191.0 0.1 2.1 1 1 0 1 1 1 1 Proline racemase DUF4338 PF14236.6 KUM58555.1 - 0.073 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) Sugar_tr PF00083.24 KUM58556.1 - 8.6e-99 331.4 20.6 1e-98 331.2 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM58556.1 - 9.1e-34 116.9 45.5 2.9e-27 95.5 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1980 PF09323.10 KUM58556.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF4211 PF13926.6 KUM58557.1 - 1.8e-42 144.8 2.4 5.9e-42 143.1 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4211) Tom22 PF04281.13 KUM58558.1 - 1e-50 171.1 1.5 1.2e-50 170.9 1.5 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 AMP-binding PF00501.28 KUM58559.1 - 3.9e-37 127.8 0.0 5.5e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KUM58559.1 - 1.2e-08 34.7 3.1 1.3e-08 34.6 1.4 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KUM58559.1 - 0.00063 20.7 0.0 0.0017 19.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.21 KUM58560.1 - 1.3e-64 218.7 0.0 1.6e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Tmemb_18A PF09771.9 KUM58560.1 - 0.089 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 188 TFIIA PF03153.13 KUM58561.1 - 0.13 12.2 35.5 0.16 11.9 35.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M16_C PF05193.21 KUM58562.1 - 1.1e-52 178.7 0.0 2.8e-52 177.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KUM58562.1 - 1.6e-40 138.5 0.0 6.9e-39 133.2 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) ADH_N PF08240.12 KUM58563.1 - 6.7e-10 38.8 0.3 2.2e-09 37.2 0.1 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM58563.1 - 2.2e-08 34.1 0.1 4.8e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 KUM58564.1 - 0.026 13.5 0.3 0.026 13.5 0.3 1.8 2 0 0 2 2 2 0 Fungal specific transcription factor domain MFS_1 PF07690.16 KUM58566.1 - 1.7e-27 96.3 49.3 1.7e-27 96.3 49.3 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM58567.1 - 7.4e-117 391.0 29.9 8.5e-117 390.8 29.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM58567.1 - 3.4e-25 88.7 33.6 1.1e-22 80.5 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2685 PF10886.8 KUM58568.1 - 3.5 7.9 8.7 0.77 10.0 0.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2685) Rhomboid PF01694.22 KUM58569.1 - 1.5e-31 109.4 6.4 1.5e-31 109.4 6.4 1.9 3 0 0 3 3 3 1 Rhomboid family TauE PF01925.19 KUM58569.1 - 3.3 7.3 14.0 6.9 6.2 6.5 2.5 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE Asparaginase PF00710.20 KUM58570.1 - 3.2e-54 183.4 0.3 1.1e-53 181.6 0.2 1.9 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KUM58570.1 - 9.9e-20 70.9 0.2 2.7e-19 69.5 0.2 1.8 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain UQ_con PF00179.26 KUM58571.1 - 1.3e-18 67.0 0.0 1.8e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KUM58571.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 RWD domain DHHC PF01529.20 KUM58572.1 - 5.3e-37 126.9 8.5 1e-36 126.0 8.5 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Nod_GRP PF07806.11 KUM58572.1 - 1.4 8.8 7.8 0.17 11.8 2.1 2.4 2 0 0 2 2 2 0 Nodule-specific GRP repeat Yip1 PF04893.17 KUM58572.1 - 3.7 7.2 13.5 0.084 12.6 2.8 2.2 2 0 0 2 2 2 0 Yip1 domain PLDc_2 PF13091.6 KUM58573.1 - 3.4e-16 59.3 0.0 7.3e-06 25.9 0.0 3.5 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KUM58573.1 - 1.9e-13 50.0 1.8 2.1e-05 24.5 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Kinetochor_Ybp2 PF08568.10 KUM58575.1 - 6.8e-148 494.0 0.0 8.4e-148 493.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin FA_hydroxylase PF04116.13 KUM58576.1 - 7.6e-22 78.1 11.7 7.6e-22 78.1 11.7 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DHDPS PF00701.22 KUM58577.1 - 3.1e-38 131.1 0.0 3.7e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.22 KUM58577.1 - 0.11 12.6 0.0 0.32 11.0 0.1 1.8 2 0 0 2 2 2 0 PA domain Fungal_trans PF04082.18 KUM58578.1 - 2.1e-30 105.7 0.1 3.3e-30 105.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KUM58579.1 - 1.5e-31 109.6 25.4 1.5e-31 109.6 25.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3040 PF11239.8 KUM58579.1 - 0.26 11.6 7.7 3.6 7.9 0.5 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) FAD_binding_3 PF01494.19 KUM58580.1 - 3.2e-25 89.1 0.0 5.4e-25 88.4 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KUM58580.1 - 1.8e-06 27.8 1.6 0.0011 18.7 0.4 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM58580.1 - 0.00022 20.5 0.9 0.0026 17.1 0.2 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KUM58580.1 - 0.00026 20.2 1.9 0.34 9.9 0.3 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KUM58580.1 - 0.00067 19.0 1.4 0.68 9.1 0.4 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KUM58580.1 - 0.0011 18.4 0.2 1 8.6 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KUM58580.1 - 0.014 15.6 0.3 0.033 14.4 0.3 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KUM58580.1 - 0.054 12.6 0.7 0.18 10.9 0.3 1.9 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KUM58580.1 - 0.11 11.6 0.9 0.21 10.6 0.3 1.7 2 1 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KUM58580.1 - 2 9.0 4.7 2 9.0 0.4 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase COesterase PF00135.28 KUM58581.1 - 2.4e-49 168.6 0.0 3e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KUM58581.1 - 5.3e-06 26.4 0.0 0.0014 18.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Alpha-L-AF_C PF06964.12 KUM58582.1 - 5.7e-23 81.9 0.0 1.3e-22 80.7 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 KUM58582.1 - 0.0072 16.6 3.1 0.017 15.4 0.9 2.5 3 0 0 3 3 3 1 Carbohydrate binding domain CTP_synth_N PF06418.14 KUM58583.1 - 2.2e-85 286.2 1.7 2.7e-85 285.9 1.7 1.0 1 0 0 1 1 1 1 CTP synthase N-terminus DUF3939 PF13075.6 KUM58583.1 - 0.025 14.6 0.0 0.048 13.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3939) Ribosomal_L5_C PF00673.21 KUM58584.1 - 1.3e-21 76.6 0.0 2.2e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KUM58584.1 - 9e-18 64.4 0.0 3.2e-17 62.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 KUM58585.1 - 1.7e-19 69.3 0.0 2e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain Clathrin PF00637.20 KUM58586.1 - 6.6e-195 638.8 34.7 1e-31 109.8 0.6 7.6 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KUM58586.1 - 3.1e-38 128.2 0.3 5.1e-09 36.0 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KUM58586.1 - 7.6e-30 102.6 3.7 7.9e-30 102.6 0.3 2.9 3 0 0 3 3 3 1 Clathrin-H-link TPR_8 PF13181.6 KUM58586.1 - 0.0039 17.3 7.3 0.38 11.1 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KUM58586.1 - 0.0049 17.6 7.3 1.8 9.6 0.1 6.5 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KUM58586.1 - 0.0064 16.4 2.6 1e+02 3.3 0.0 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KUM58586.1 - 0.043 14.1 0.7 42 4.5 0.0 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KUM58586.1 - 0.087 12.7 0.5 6.6 6.7 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KUM58586.1 - 0.096 12.9 3.8 7.8 6.9 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF5497 PF17601.2 KUM58586.1 - 0.14 12.5 1.7 13 6.1 0.2 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5497) Imm5 PF14423.6 KUM58586.1 - 0.53 10.5 3.6 0.56 10.4 0.0 2.8 3 0 0 3 3 3 0 Immunity protein Imm5 Utp13 PF08625.11 KUM58586.1 - 0.73 9.7 10.0 3.4 7.6 0.1 5.0 4 1 1 5 5 5 0 Utp13 specific WD40 associated domain Vps39_1 PF10366.9 KUM58586.1 - 1 9.7 9.1 65 3.9 0.0 6.0 4 1 1 5 5 5 0 Vacuolar sorting protein 39 domain 1 Sugar_tr PF00083.24 KUM58587.1 - 6.1e-27 94.6 26.2 2.5e-26 92.6 26.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM58587.1 - 7.9e-21 74.4 41.7 3.1e-17 62.5 13.7 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily AA_permease PF00324.21 KUM58589.1 - 2e-49 168.5 22.0 2.5e-49 168.2 22.0 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KUM58589.1 - 7.2e-19 68.1 0.5 1.2e-06 27.9 0.0 3.2 3 0 0 3 3 3 3 Solute carrier family 12 MPC PF03650.13 KUM58590.1 - 2.2e-36 124.3 0.4 4.5e-35 120.1 0.1 2.2 1 1 1 2 2 2 1 Mitochondrial pyruvate carriers Phage_Coat_B PF05356.11 KUM58590.1 - 0.087 12.7 0.1 0.17 11.8 0.1 1.5 1 1 0 1 1 1 0 Phage Coat protein B Aa_trans PF01490.18 KUM58591.1 - 3.6e-84 282.9 31.2 4.5e-84 282.5 31.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CPSase_L_D2 PF02786.17 KUM58593.1 - 3.9e-78 261.8 0.1 6.2e-78 261.1 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KUM58593.1 - 2e-66 223.5 0.0 3.5e-66 222.7 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KUM58593.1 - 1.8e-39 134.7 0.1 3.4e-39 133.8 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KUM58593.1 - 8.9e-30 103.0 0.0 3e-29 101.3 0.0 2.0 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KUM58593.1 - 6.5e-27 94.7 0.0 1.3e-26 93.8 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KUM58593.1 - 3.4e-17 62.0 4.0 4e-17 61.8 2.1 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KUM58593.1 - 3.3e-10 39.6 4.4 6e-06 26.0 0.2 3.3 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KUM58593.1 - 2.4e-07 30.5 0.0 4.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KUM58593.1 - 2.9e-07 30.2 0.0 6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KUM58593.1 - 5.8e-06 26.4 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KUM58593.1 - 8.7e-05 21.8 0.1 0.015 14.5 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 KUM58593.1 - 0.00084 20.0 0.5 5.6 7.7 0.0 3.7 4 0 0 4 4 4 2 HlyD family secretion protein RnfC_N PF13375.6 KUM58593.1 - 0.014 15.4 0.7 2.1 8.4 0.2 3.0 2 1 1 3 3 3 0 RnfC Barrel sandwich hybrid domain GARS_A PF01071.19 KUM58593.1 - 0.034 13.9 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KUM58593.1 - 0.04 13.5 0.0 0.096 12.3 0.0 1.6 1 1 0 1 1 1 0 RimK-like ATP-grasp domain GCV_H PF01597.19 KUM58593.1 - 0.17 11.8 1.1 1.3 8.9 0.2 2.7 2 1 1 3 3 3 0 Glycine cleavage H-protein GATase PF00117.28 KUM58594.1 - 1.6e-47 161.7 0.2 2.2e-47 161.3 0.2 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KUM58594.1 - 3.6e-09 36.7 0.3 1.1e-08 35.2 0.3 1.8 1 1 0 1 1 1 1 Peptidase C26 CTP_synth_N PF06418.14 KUM58594.1 - 6.5e-05 22.4 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus AdoMet_Synthase PF01941.19 KUM58594.1 - 0.035 12.9 0.2 0.054 12.3 0.2 1.2 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) GHMP_kinases_N PF00288.26 KUM58595.1 - 1.6e-14 53.9 0.0 3.9e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KUM58595.1 - 1.4e-07 31.8 0.0 4.8e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KUM58595.1 - 0.0015 18.0 0.1 0.0031 17.0 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Hydantoinase_B PF02538.14 KUM58596.1 - 2.1e-13 49.6 0.0 2.1e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Aldedh PF00171.22 KUM58597.1 - 6.7e-13 48.0 10.2 4.7e-11 41.9 7.4 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 KUM58597.1 - 0.012 15.1 0.1 0.028 13.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Ribosomal_L18 PF17135.4 KUM58598.1 - 6.9e-91 302.7 3.2 9.6e-91 302.3 3.2 1.2 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KUM58598.1 - 0.00074 20.2 0.4 0.0023 18.6 0.4 2.1 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A PCI PF01399.27 KUM58599.1 - 0.11 13.1 0.0 0.29 11.6 0.0 1.8 1 1 0 1 1 1 0 PCI domain MBOAT PF03062.19 KUM58601.1 - 6.9e-28 98.0 22.0 1.3e-27 97.1 11.6 3.2 2 2 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family DLH PF01738.18 KUM58601.1 - 1e-26 93.9 0.0 1.6e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family MBOAT_2 PF13813.6 KUM58601.1 - 3.5e-05 24.0 2.7 9.2e-05 22.6 2.7 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family UPF0093 PF03653.13 KUM58601.1 - 3.5 7.8 12.8 0.91 9.8 7.8 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0093) Pneumo_att_G PF05539.11 KUM58602.1 - 1.9 8.0 7.2 2 7.9 7.2 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Peptidase_M24 PF00557.24 KUM58603.1 - 9.1e-54 182.3 0.2 1.3e-53 181.8 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KUM58603.1 - 3.1e-26 91.5 0.0 7e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Zn_clus PF00172.18 KUM58604.1 - 8.4e-09 35.4 7.4 8.4e-09 35.4 7.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydantoinase_B PF02538.14 KUM58605.1 - 5.3e-114 381.5 0.0 7.3e-114 381.0 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KUM58605.1 - 3.5e-101 338.3 0.3 3.5e-101 338.3 0.3 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KUM58605.1 - 1.2e-59 201.0 0.8 6e-58 195.5 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region RRM_1 PF00076.22 KUM58606.1 - 1e-11 44.5 0.0 1.4e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KUM58606.1 - 0.0007 19.5 0.0 0.00099 19.1 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif BTB PF00651.31 KUM58608.1 - 0.00089 19.5 0.1 0.003 17.8 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain Mito_carr PF00153.27 KUM58609.1 - 5.9e-73 240.9 2.2 4e-24 84.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KUM58609.1 - 6.9e-05 22.1 0.6 0.003 16.8 0.0 3.1 2 1 0 3 3 3 1 Gammaproteobacterial serine protease PrcB_C PF14343.6 KUM58609.1 - 0.11 12.7 0.1 2.8 8.2 0.0 2.5 2 0 0 2 2 2 0 PrcB C-terminal PXA PF02194.15 KUM58611.1 - 5.4e-34 117.8 0.0 9.8e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KUM58611.1 - 1.3e-22 80.5 0.0 4.2e-22 78.8 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KUM58611.1 - 6.1e-10 39.1 0.1 1e-08 35.1 0.0 2.4 2 0 0 2 2 2 1 PX domain PC4 PF02229.16 KUM58612.1 - 1e-22 79.5 0.1 1.6e-22 78.9 0.1 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) CH PF00307.31 KUM58613.1 - 1.1e-73 244.3 0.0 8.5e-21 74.2 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KUM58613.1 - 1e-05 25.9 1.1 0.00025 21.4 0.2 3.2 3 0 0 3 3 3 1 EF-hand domain pair CAMSAP_CH PF11971.8 KUM58613.1 - 0.0011 18.7 0.0 0.38 10.6 0.0 3.5 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_6 PF13405.6 KUM58613.1 - 0.018 15.0 0.2 3.6 7.7 0.0 3.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 KUM58613.1 - 0.11 12.1 0.5 12 5.7 0.1 3.3 3 0 0 3 3 3 0 EF hand DDHD PF02862.17 KUM58614.1 - 2.9e-60 204.2 0.0 1.1e-57 195.7 0.0 2.4 2 0 0 2 2 2 2 DDHD domain RNase_3_N PF18497.1 KUM58614.1 - 0.029 14.6 0.0 0.25 11.6 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease III N-terminal domain Arf PF00025.21 KUM58617.1 - 2.1e-39 134.8 0.0 7.8e-26 90.6 0.0 2.3 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 KUM58617.1 - 6.1e-14 51.9 0.0 4.8e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KUM58617.1 - 2e-10 40.9 0.0 8.4e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KUM58617.1 - 1.6e-06 28.2 0.0 3.3e-06 27.1 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 KUM58617.1 - 2e-06 27.5 0.0 0.0014 18.2 0.0 2.7 2 1 0 2 2 2 2 Ras family Gtr1_RagA PF04670.12 KUM58617.1 - 6.2e-06 25.7 0.0 8.4e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KUM58617.1 - 9.7e-06 25.1 0.0 8.2e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KUM58617.1 - 0.00033 20.3 0.0 0.014 15.0 0.0 2.4 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KUM58617.1 - 0.077 12.5 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 KUM58617.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Abhydrolase_6 PF12697.7 KUM58618.1 - 9e-06 26.4 0.0 1e-05 26.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family FAD_binding_4 PF01565.23 KUM58619.1 - 8.1e-06 25.6 0.0 1.4e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain PIGA PF08288.12 KUM58621.1 - 5.8e-46 155.0 2.2 1.3e-45 153.9 1.0 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 KUM58621.1 - 8.1e-27 93.8 0.0 1.3e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KUM58621.1 - 4.3e-24 85.5 0.0 8.9e-24 84.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KUM58621.1 - 1.9e-23 83.3 0.3 3.1e-23 82.6 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KUM58621.1 - 2e-08 34.8 0.0 3.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KUM58621.1 - 0.00088 19.6 0.0 0.024 15.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KUM58621.1 - 0.00099 19.1 0.1 0.0022 18.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like DEAD PF00270.29 KUM58622.1 - 1.3e-34 119.4 0.0 4.7e-16 59.0 0.0 2.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM58622.1 - 5e-20 71.9 0.1 1.6e-19 70.3 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM58622.1 - 5.2e-07 29.8 0.0 2.6e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Nop14 PF04147.12 KUM58622.1 - 2.9 6.0 36.7 0.011 14.0 10.8 2.1 2 0 0 2 2 2 0 Nop14-like family Glyco_hydro_3_C PF01915.22 KUM58623.1 - 1.2e-46 159.2 0.0 2e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KUM58623.1 - 6.5e-36 124.3 0.0 1.8e-35 122.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KUM58623.1 - 6.1e-08 32.7 0.0 1.8e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain DDR PF08841.10 KUM58623.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Ank_2 PF12796.7 KUM58625.1 - 1.5e-58 195.3 10.9 6.8e-14 52.2 0.7 5.6 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM58625.1 - 8.3e-43 144.2 17.7 5.6e-09 36.4 0.0 7.7 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM58625.1 - 5.4e-33 109.3 2.9 0.0034 17.8 0.0 10.0 10 0 0 10 10 10 7 Ankyrin repeat Ank PF00023.30 KUM58625.1 - 5.7e-31 105.6 16.0 0.0012 19.1 0.0 10.4 9 1 1 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KUM58625.1 - 2.3e-22 78.8 10.5 3.8e-07 30.2 0.1 7.1 2 2 4 7 7 7 6 Ankyrin repeats (many copies) NACHT PF05729.12 KUM58625.1 - 4e-05 23.6 0.0 8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KUM58625.1 - 0.00012 22.4 0.0 0.00025 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain PTS_IIA PF02255.16 KUM58625.1 - 0.32 11.1 2.1 15 5.7 0.3 2.7 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Glyco_transf_43 PF03360.16 KUM58626.1 - 0.14 11.9 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 43 Ank_2 PF12796.7 KUM58627.1 - 9.9e-50 167.1 13.3 1.3e-13 51.3 0.3 4.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM58627.1 - 4.9e-37 125.8 9.4 5.1e-09 36.5 0.0 5.7 4 1 1 5 5 5 5 Ankyrin repeats (many copies) SRP19 PF01922.17 KUM58627.1 - 1.3e-33 115.8 0.0 2.8e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 SRP19 protein Ank_3 PF13606.6 KUM58627.1 - 3.3e-25 85.4 9.7 0.029 14.9 0.0 10.2 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 KUM58627.1 - 1.5e-19 69.8 13.5 7.2e-05 23.0 0.1 7.4 2 2 7 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 KUM58627.1 - 7.9e-19 67.2 18.5 0.034 14.6 0.0 9.4 9 0 0 9 9 9 6 Ankyrin repeat NACHT PF05729.12 KUM58627.1 - 4.3e-07 30.0 0.0 9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Goodbye PF17109.5 KUM58627.1 - 1.5e-05 25.4 0.1 4.2e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain AAA_16 PF13191.6 KUM58627.1 - 0.0013 19.1 0.9 0.012 16.0 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 KUM58627.1 - 0.0031 17.9 0.0 0.093 13.1 0.0 2.9 3 0 0 3 3 3 1 RNA helicase AAA_22 PF13401.6 KUM58627.1 - 0.14 12.4 0.0 0.47 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain MFS18 PF17352.2 KUM58627.1 - 5.1 7.5 10.8 12 6.3 10.8 1.6 1 0 0 1 1 1 0 Male Flower Specific protein 18 FA_hydroxylase PF04116.13 KUM58629.1 - 1.2e-23 83.9 13.4 1.2e-23 83.9 13.4 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily XFP_C PF09363.10 KUM58629.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 XFP C-terminal domain Fungal_trans PF04082.18 KUM58630.1 - 3.7e-14 52.4 0.1 6.6e-14 51.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM58630.1 - 1.9e-11 43.9 10.6 3.3e-11 43.1 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TCTP PF00838.17 KUM58631.1 - 6.4e-51 173.0 0.2 7.3e-51 172.8 0.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein SPOUT_MTase PF02590.17 KUM58631.1 - 0.063 13.3 0.2 0.41 10.6 0.1 1.9 1 1 1 2 2 2 0 Predicted SPOUT methyltransferase TSKS PF15358.6 KUM58633.1 - 0.084 11.2 1.1 0.11 10.8 1.1 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate DUF908 PF06012.12 KUM58633.1 - 1.4 8.3 11.1 1.8 7.9 11.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) MFS_1 PF07690.16 KUM58635.1 - 6.6e-21 74.6 40.1 7.6e-20 71.1 39.6 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Ras PF00071.22 KUM58636.1 - 2.5e-52 176.8 0.0 2.9e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM58636.1 - 7.1e-19 68.2 0.0 9.5e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM58636.1 - 7.3e-06 25.5 0.0 1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Arginase PF00491.21 KUM58637.1 - 3.4e-93 312.2 0.0 4.4e-93 311.8 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KUM58637.1 - 0.0004 20.7 0.0 0.00077 19.7 0.0 1.4 1 0 0 1 1 1 1 UPF0489 domain Ketoacyl-synt_C PF02801.22 KUM58640.1 - 5.1e-25 87.8 0.8 6.2e-25 87.5 0.8 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SCA7 PF08313.12 KUM58641.1 - 3.4e-30 103.7 2.6 3.4e-30 103.7 2.6 2.5 2 0 0 2 2 2 1 SCA7, zinc-binding domain CDC45 PF02724.14 KUM58641.1 - 0.77 8.0 13.1 1.1 7.4 13.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 KUM58641.1 - 5.7 6.1 4.6 8.5 5.5 4.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 KUM58641.1 - 10 5.0 6.8 21 4.0 6.8 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1349 PF07081.11 KUM58642.1 - 8.5e-29 100.5 0.0 1e-28 100.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) mRNA_cap_enzyme PF01331.19 KUM58643.1 - 6.7e-53 179.4 0.1 9.2e-53 179.0 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KUM58643.1 - 2e-33 115.2 0.1 3.4e-33 114.5 0.1 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KUM58643.1 - 2.8e-07 30.4 0.1 3.6e-06 26.8 0.0 2.4 1 1 1 2 2 2 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KUM58643.1 - 0.00021 21.6 0.0 0.028 14.8 0.0 2.2 2 0 0 2 2 2 2 RNA ligase MOZ_SAS PF01853.18 KUM58644.1 - 1.3e-79 266.0 0.0 1.9e-79 265.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 KUM58644.1 - 4.4e-23 80.9 0.0 9.3e-23 79.9 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 KUM58644.1 - 2.8e-21 74.9 0.1 6e-21 73.8 0.1 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KUM58644.1 - 0.0044 17.4 0.0 0.009 16.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM58644.1 - 0.037 14.3 0.0 0.096 12.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CAP59_mtransfer PF11735.8 KUM58645.1 - 1.7e-75 253.9 0.0 2.1e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Peptidase_M14 PF00246.24 KUM58647.1 - 2.4e-80 270.5 0.0 2.9e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.20 KUM58648.1 - 2.2e-29 102.5 0.2 3.5e-29 101.8 0.2 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KUM58648.1 - 6e-05 23.5 0.1 0.00014 22.3 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KUM58648.1 - 8.3e-05 22.9 0.3 0.00017 21.9 0.3 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain p450 PF00067.22 KUM58648.1 - 0.011 14.6 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome P450 Zip PF02535.22 KUM58649.1 - 1e-22 80.8 14.2 7.3e-15 55.0 8.0 2.3 1 1 0 2 2 2 2 ZIP Zinc transporter DUF2975 PF11188.8 KUM58649.1 - 2.1 8.3 9.2 1.2 9.0 4.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) zf-RING_UBOX PF13445.6 KUM58650.1 - 3.3e-06 27.0 11.0 0.00016 21.7 4.5 2.8 2 1 0 2 2 2 2 RING-type zinc-finger zf-NOSIP PF15906.5 KUM58650.1 - 4.9e-05 23.4 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 KUM58650.1 - 0.00011 21.6 12.9 0.00086 18.7 1.9 2.8 2 1 1 3 3 3 2 Rtf2 RING-finger zf-RING_2 PF13639.6 KUM58650.1 - 0.0002 21.6 12.9 0.0019 18.5 3.6 2.9 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 KUM58650.1 - 0.00027 20.7 12.2 0.00078 19.2 5.0 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KUM58650.1 - 0.00056 19.8 7.6 0.00056 19.8 7.6 2.6 2 2 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KUM58650.1 - 0.0012 18.7 14.2 0.0072 16.2 3.9 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM58650.1 - 0.002 18.0 4.6 0.002 18.0 4.6 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Atg14 PF10186.9 KUM58650.1 - 0.0048 16.0 2.9 0.0048 16.0 2.9 1.7 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 FYVE PF01363.21 KUM58650.1 - 0.057 13.6 14.1 0.029 14.5 5.2 3.0 2 2 1 3 3 3 0 FYVE zinc finger Vps39_2 PF10367.9 KUM58650.1 - 0.07 13.6 1.1 0.07 13.6 1.1 3.4 4 0 0 4 4 4 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_5 PF17121.5 KUM58650.1 - 0.098 12.6 2.8 0.27 11.1 2.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KUM58650.1 - 1.3 9.3 11.7 0.38 11.0 2.1 3.3 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING DUF4407 PF14362.6 KUM58650.1 - 4.1 6.7 8.4 0.33 10.3 3.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Prok-RING_4 PF14447.6 KUM58650.1 - 4.3 7.3 19.8 3.7 7.5 8.7 3.7 3 1 1 4 4 3 0 Prokaryotic RING finger family 4 IBR PF01485.21 KUM58650.1 - 8.3 6.7 10.1 5.9 7.2 0.9 3.0 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain Endonuclease_NS PF01223.23 KUM58651.1 - 9.7e-64 215.3 0.0 1.2e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Sedlin_N PF04628.13 KUM58652.1 - 1.2e-42 145.1 0.0 1.4e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KUM58652.1 - 0.0011 18.9 0.0 0.006 16.5 0.0 1.9 2 0 0 2 2 2 1 Sybindin-like family Ribosomal_S30 PF04758.14 KUM58653.1 - 1.1e-25 89.6 6.0 1.1e-25 89.6 6.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S30 DUF2040 PF09745.9 KUM58654.1 - 2.3e-37 127.7 19.8 2.3e-37 127.7 19.8 3.6 4 1 0 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) NB-ARC PF00931.22 KUM58655.1 - 1e-05 24.8 0.0 3.3e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 KUM58655.1 - 1.6e-05 24.9 0.0 6.2e-05 23.0 0.0 2.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KUM58655.1 - 8.8e-05 22.9 1.6 0.00026 21.4 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KUM58655.1 - 0.001 19.4 0.0 0.0075 16.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain TPR_7 PF13176.6 KUM58655.1 - 0.0019 18.1 7.0 1.1 9.4 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 KUM58655.1 - 0.0031 18.2 1.5 35 5.6 0.0 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KUM58655.1 - 0.0035 17.6 16.6 3.1 8.1 0.7 7.7 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 KUM58655.1 - 0.0037 17.7 4.4 2.2 8.8 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat AAA_19 PF13245.6 KUM58655.1 - 0.0049 17.2 0.0 0.021 15.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KUM58655.1 - 0.054 12.8 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin SH3_6 PF12913.7 KUM58656.1 - 0.15 11.7 1.1 3.6 7.2 0.1 2.9 3 0 0 3 3 3 0 SH3 domain (SH3b1 type) DASH_Dam1 PF08653.10 KUM58656.1 - 0.92 9.4 4.9 2 8.3 0.2 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 NicO PF03824.16 KUM58657.1 - 3.8e-62 210.2 14.1 1.3e-58 198.6 6.2 2.3 2 0 0 2 2 2 2 High-affinity nickel-transport protein AA_permease PF00324.21 KUM58658.1 - 2.9e-128 428.5 36.8 3.6e-128 428.2 36.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM58658.1 - 1.2e-37 129.8 37.5 1.5e-37 129.4 37.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4500 PF14937.6 KUM58658.1 - 3.7 7.6 5.2 27 4.9 0.0 3.7 4 1 1 5 5 5 0 Domain of unknown function (DUF4500) Sugar_tr PF00083.24 KUM58659.1 - 5e-48 164.1 9.2 5.3e-48 164.0 9.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM58659.1 - 1.2e-09 37.6 5.7 1.7e-09 37.1 5.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Metallophos PF00149.28 KUM58661.1 - 1.1e-16 62.0 0.6 2.5e-16 60.8 0.2 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KUM58661.1 - 2.8e-06 27.6 0.0 5.1e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Epimerase_2 PF02350.19 KUM58661.1 - 0.22 10.4 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Exo_endo_phos PF03372.23 KUM58662.1 - 1.7e-16 60.5 0.0 1.4e-15 57.4 0.0 2.4 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 KUM58662.1 - 2e-10 40.7 8.5 4.4e-06 26.9 1.3 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KUM58662.1 - 6.1e-10 38.7 5.8 2.5e-08 33.6 6.4 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KUM58662.1 - 0.12 13.0 6.0 9.6 7.2 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat tRNA-synt_1 PF00133.22 KUM58663.1 - 6.2e-38 130.4 0.0 4.9e-27 94.4 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KUM58663.1 - 5.5e-18 64.9 0.1 6.6e-11 41.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KUM58663.1 - 1.7e-17 63.8 0.1 1.1e-16 61.1 0.1 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KUM58663.1 - 1.6e-07 31.0 0.0 3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KUM58663.1 - 0.0037 16.2 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (K) GATA PF00320.27 KUM58664.1 - 1.8e-15 56.3 6.3 3.5e-15 55.3 6.3 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 KUM58664.1 - 4.4e-10 39.7 0.0 8e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KUM58664.1 - 2.1e-07 30.9 0.1 1.3e-06 28.4 0.0 2.3 2 1 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KUM58664.1 - 3.3e-06 27.3 0.0 1.6e-05 25.1 0.0 2.1 2 1 1 3 3 3 1 PAS domain PAS_4 PF08448.10 KUM58664.1 - 3.7e-06 27.1 0.0 8.6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold P_C PF06640.11 KUM58664.1 - 0.00052 20.2 2.1 0.00098 19.3 2.1 1.4 1 0 0 1 1 1 1 P protein C-terminus PAS_8 PF13188.7 KUM58664.1 - 0.015 15.3 0.0 0.037 14.1 0.0 1.7 1 1 0 1 1 1 0 PAS domain Nudix_N_2 PF14803.6 KUM58664.1 - 8.8 6.3 6.8 5.6 7.0 2.3 2.4 1 1 1 2 2 2 0 Nudix N-terminal Aminotran_1_2 PF00155.21 KUM58665.1 - 1.4e-40 139.6 0.0 6.3e-40 137.5 0.0 1.7 1 1 1 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KUM58665.1 - 4.7e-05 22.8 0.0 7.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase BBL5 PF07289.11 KUM58665.1 - 0.051 12.6 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein NAD_binding_1 PF00175.21 KUM58668.1 - 6.3e-07 30.0 0.0 0.015 15.9 0.0 2.6 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KUM58668.1 - 1.2e-05 25.5 0.1 0.00017 21.7 0.1 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain SopE_GEF PF07487.13 KUM58668.1 - 0.062 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 SopE GEF domain HAD PF12710.7 KUM58669.1 - 4.4e-23 82.7 0.0 5.6e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TSNAXIP1_N PF15739.5 KUM58669.1 - 0.0043 17.4 0.0 0.007 16.7 0.0 1.2 1 0 0 1 1 1 1 Translin-associated factor X-interacting N-terminus Put_Phosphatase PF06888.12 KUM58669.1 - 0.0057 16.1 0.0 0.11 11.9 0.0 2.0 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.26 KUM58669.1 - 0.046 14.0 1.3 4 7.7 0.0 3.0 2 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KUM58669.1 - 0.052 13.0 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) FMN_red PF03358.15 KUM58670.1 - 1e-24 87.0 0.0 1.5e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KUM58670.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin-like fold Hydrolase_4 PF12146.8 KUM58671.1 - 2.1e-47 161.4 0.0 2.6e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KUM58671.1 - 9.9e-10 39.4 0.2 1.6e-09 38.7 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM58671.1 - 4.6e-08 33.0 0.2 2.1e-07 30.9 0.1 2.0 2 1 1 3 3 3 1 alpha/beta hydrolase fold DLH PF01738.18 KUM58671.1 - 0.0025 17.4 0.0 0.016 14.8 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KUM58671.1 - 0.019 14.4 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_S10 PF00450.22 KUM58671.1 - 0.034 13.6 0.0 3.2 7.1 0.0 2.1 2 0 0 2 2 2 0 Serine carboxypeptidase Chlorophyllase2 PF12740.7 KUM58671.1 - 0.13 11.1 0.0 0.25 10.2 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme SMC_N PF02463.19 KUM58672.1 - 1e-09 38.2 3.2 1e-09 38.2 3.2 2.7 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KUM58672.1 - 1.2e-06 28.7 0.0 5.1e-06 26.6 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KUM58672.1 - 0.00012 22.7 7.2 0.00012 22.7 7.2 8.2 3 2 1 4 4 4 1 AAA domain KNOX2 PF03791.13 KUM58672.1 - 0.0053 16.2 0.3 0.25 10.9 0.4 3.2 2 0 0 2 2 2 1 KNOX2 domain T3SS_needle_E PF08988.10 KUM58672.1 - 0.11 12.7 0.0 0.11 12.7 0.0 6.1 7 0 0 7 7 7 0 Type III secretion system, cytoplasmic E component of needle DASH_Dam1 PF08653.10 KUM58672.1 - 3.9 7.3 10.9 16 5.4 1.0 5.4 4 0 0 4 4 4 0 DASH complex subunit Dam1 GCD14 PF08704.10 KUM58673.1 - 2.5e-08 33.9 0.0 0.00082 19.1 0.0 2.3 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 KUM58673.1 - 1.9e-05 24.4 0.1 4.9e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_25 PF13649.6 KUM58673.1 - 0.042 14.5 0.0 12 6.7 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain L51_S25_CI-B8 PF05047.16 KUM58674.1 - 1.5e-20 72.8 0.0 3.2e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain COesterase PF00135.28 KUM58675.1 - 2e-89 300.8 0.0 9.1e-78 262.4 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KUM58675.1 - 1.6e-13 51.0 0.1 2.5e-13 50.4 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans PF04082.18 KUM58676.1 - 1.5e-17 63.5 0.6 8e-17 61.1 0.5 2.1 1 1 1 2 2 2 1 Fungal specific transcription factor domain Iso_dh PF00180.20 KUM58677.1 - 3e-83 279.9 0.0 3.6e-83 279.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PRK PF00485.18 KUM58678.1 - 7.6e-06 25.8 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KUM58678.1 - 0.00019 20.8 0.0 0.00053 19.3 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin MeaB PF03308.16 KUM58678.1 - 0.0041 16.1 0.0 0.0066 15.5 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KUM58678.1 - 0.0041 17.3 0.1 0.02 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KUM58678.1 - 0.0043 17.6 0.0 0.015 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KUM58678.1 - 0.0062 16.3 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain APS_kinase PF01583.20 KUM58678.1 - 0.0064 16.4 0.1 0.033 14.1 0.0 2.0 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_14 PF13173.6 KUM58678.1 - 0.015 15.3 0.0 0.038 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AKAP95 PF04988.12 KUM58678.1 - 0.016 15.4 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) DUF815 PF05673.13 KUM58678.1 - 0.022 13.9 0.0 0.072 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KUM58678.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF463 PF04317.12 KUM58678.1 - 0.06 12.3 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_16 PF13191.6 KUM58678.1 - 0.083 13.3 0.0 0.35 11.3 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain SKG6 PF08693.10 KUM58679.1 - 1e-06 28.1 0.3 1e-06 28.1 0.3 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Glycophorin_A PF01102.18 KUM58679.1 - 0.00016 21.9 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 Glycophorin A Podoplanin PF05808.11 KUM58679.1 - 0.0044 17.1 2.1 0.0064 16.6 2.1 1.2 1 0 0 1 1 1 1 Podoplanin MGC-24 PF05283.11 KUM58679.1 - 0.0083 16.6 1.4 0.012 16.1 1.4 1.2 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin SSP160 PF06933.11 KUM58679.1 - 0.017 13.3 4.7 0.022 13.0 4.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Gram_pos_anchor PF00746.21 KUM58679.1 - 0.022 14.7 0.1 0.053 13.5 0.1 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif TMEM154 PF15102.6 KUM58679.1 - 0.033 14.1 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 KUM58679.1 - 0.034 12.9 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Nitrate_red_gam PF02665.14 KUM58679.1 - 0.079 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF5305 PF17231.2 KUM58679.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Syndecan PF01034.20 KUM58679.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Syndecan domain Herpes_gE PF02480.16 KUM58679.1 - 0.17 10.6 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CD34_antigen PF06365.12 KUM58679.1 - 0.19 11.3 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DHO_dh PF01180.21 KUM58681.1 - 5.5e-67 226.1 0.0 4.2e-65 219.9 0.0 2.1 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KUM58681.1 - 8.8e-06 25.0 0.0 0.0011 18.1 0.0 2.5 2 1 0 2 2 2 2 FMN-dependent dehydrogenase PcrB PF01884.17 KUM58681.1 - 0.0042 16.6 0.3 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 PcrB family TIM PF00121.18 KUM58682.1 - 6.3e-40 137.1 0.0 8.3e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.18 KUM58683.1 - 1.7e-43 148.0 0.0 1.9e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase URO-D PF01208.17 KUM58683.1 - 0.039 13.1 0.0 0.076 12.2 0.0 1.4 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) U-box PF04564.15 KUM58684.1 - 5.2e-21 74.6 0.0 9.7e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 KUM58684.1 - 4.2e-09 35.8 4.6 9e-05 22.3 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KUM58684.1 - 4e-08 32.7 2.8 1.3e-05 24.8 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KUM58684.1 - 1.6e-06 27.6 1.4 2.9e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 KUM58684.1 - 2.5e-06 28.0 5.6 0.0093 16.6 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KUM58684.1 - 1.2e-05 25.7 0.7 0.0067 16.9 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KUM58684.1 - 1.5e-05 25.4 7.1 0.0057 17.4 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KUM58684.1 - 3e-05 24.1 0.3 0.041 14.3 0.0 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KUM58684.1 - 0.00045 20.5 1.3 0.11 12.9 0.7 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM58684.1 - 0.0047 17.1 0.2 1.3 9.3 0.1 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 CHIP_TPR_N PF18391.1 KUM58684.1 - 0.024 15.4 0.4 0.049 14.4 0.4 1.5 1 0 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain TPR_3 PF07720.12 KUM58684.1 - 0.25 11.4 1.5 0.75 9.9 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KUM58684.1 - 5.4 7.2 7.0 18 5.5 0.2 3.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain ACBP PF00887.19 KUM58685.1 - 7.9e-13 48.4 0.3 1.4e-12 47.6 0.3 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein TRH PF05438.12 KUM58685.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) Tyr-DNA_phospho PF06087.12 KUM58686.1 - 9.8e-169 561.7 0.0 1.1e-168 561.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 KUM58686.1 - 0.013 15.4 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 PLD-like domain Gly_transf_sug PF04488.15 KUM58687.1 - 6.1e-07 30.0 0.0 1.2e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KUM58687.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein RRN3 PF05327.11 KUM58688.1 - 1.3e-174 581.9 0.0 1.7e-174 581.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Actin PF00022.19 KUM58691.1 - 1.3e-31 109.7 0.0 7.6e-19 67.6 0.0 2.4 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 KUM58691.1 - 6.8e-06 25.1 0.0 0.00053 18.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Actin_micro PF17003.5 KUM58691.1 - 0.00063 19.0 0.5 0.0016 17.7 0.3 1.7 2 0 0 2 2 2 1 Putative actin-like family FtsA PF14450.6 KUM58691.1 - 0.0036 17.7 0.0 0.011 16.2 0.0 2.0 2 1 0 2 2 2 1 Cell division protein FtsA Titin_Ig-rpts PF06582.12 KUM58691.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Titin repeat DUF2114 PF09887.9 KUM58691.1 - 0.13 10.8 0.1 0.17 10.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Paf1 PF03985.13 KUM58692.1 - 1.4e-53 182.4 0.0 2.8e-53 181.5 0.0 1.4 1 1 0 1 1 1 1 Paf1 ADH_zinc_N PF00107.26 KUM58693.1 - 6.2e-26 90.9 0.3 9.1e-26 90.4 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM58693.1 - 2.8e-15 57.5 0.1 4.1e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM58693.1 - 1.5e-06 28.1 0.3 2.6e-06 27.3 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glucokinase PF02685.16 KUM58693.1 - 0.052 12.5 0.1 0.092 11.7 0.1 1.3 1 0 0 1 1 1 0 Glucokinase Fer4_6 PF12837.7 KUM58693.1 - 0.055 13.6 0.7 0.12 12.5 0.7 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain Arf PF00025.21 KUM58694.1 - 5.8e-70 234.3 0.1 6.8e-70 234.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KUM58694.1 - 1.1e-12 48.3 0.0 1.6e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KUM58694.1 - 3.9e-10 39.5 0.0 5.1e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KUM58694.1 - 2.4e-09 36.8 0.1 2.8e-05 23.5 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KUM58694.1 - 2.7e-09 36.9 0.0 3.4e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KUM58694.1 - 4.1e-07 29.6 0.0 9.1e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KUM58694.1 - 2.4e-05 24.4 0.0 6.5e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KUM58694.1 - 0.0003 20.4 0.0 0.045 13.3 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KUM58694.1 - 0.037 13.5 0.4 0.22 11.0 0.4 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B ADH_N PF08240.12 KUM58695.1 - 3.5e-25 88.0 0.0 9.4e-25 86.6 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM58695.1 - 2.1e-18 66.5 0.9 3.5e-18 65.8 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM58695.1 - 0.00042 21.4 0.0 0.00069 20.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ISN1 PF06437.11 KUM58696.1 - 2.6e-200 665.6 0.0 2.9e-200 665.4 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Med17 PF10156.9 KUM58697.1 - 2.5e-102 343.0 0.1 3.2e-102 342.6 0.1 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DAO PF01266.24 KUM58698.1 - 1.8e-40 139.6 0.1 2.1e-40 139.4 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KUM58698.1 - 0.00011 22.4 0.8 0.00024 21.3 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KUM58698.1 - 0.00018 21.6 0.0 0.0084 16.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KUM58698.1 - 0.0017 17.6 0.0 0.0035 16.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KUM58698.1 - 0.0097 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KUM58698.1 - 0.083 12.2 0.4 0.28 10.4 0.1 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KUM58698.1 - 0.15 11.0 0.1 0.24 10.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein adh_short PF00106.25 KUM58699.1 - 1.2e-23 83.6 0.0 1.5e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM58699.1 - 3.6e-23 82.3 0.0 4.1e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_hydro_76 PF03663.14 KUM58700.1 - 3.3e-162 540.1 23.1 3.9e-162 539.9 23.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KUM58700.1 - 0.00011 21.4 8.6 0.13 11.3 0.0 3.2 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 SurE PF01975.17 KUM58701.1 - 1.2e-33 116.5 0.3 1.6e-33 116.1 0.3 1.1 1 0 0 1 1 1 1 Survival protein SurE ABC2_membrane PF01061.24 KUM58702.1 - 2.1e-81 272.4 50.5 1.9e-48 164.6 19.9 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KUM58702.1 - 3.9e-40 137.5 0.0 1.5e-18 67.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KUM58702.1 - 7.9e-24 83.4 15.0 3.6e-22 78.1 0.1 4.4 4 0 0 4 4 4 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KUM58702.1 - 9.2e-11 41.4 9.7 9.2e-11 41.4 9.7 2.7 3 1 0 3 3 2 1 ABC-2 family transporter protein AAA_16 PF13191.6 KUM58702.1 - 3.1e-07 30.9 0.0 0.00047 20.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KUM58702.1 - 5.4e-07 29.7 0.0 0.33 10.7 0.0 4.0 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KUM58702.1 - 3.6e-05 23.7 0.1 0.0013 18.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KUM58702.1 - 7.9e-05 22.2 0.0 0.038 13.4 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KUM58702.1 - 0.0001 22.9 0.1 0.11 13.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 KUM58702.1 - 0.00029 20.5 0.4 0.079 12.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KUM58702.1 - 0.00082 19.1 0.1 0.025 14.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KUM58702.1 - 0.0049 17.1 0.0 0.44 10.8 0.1 3.0 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KUM58702.1 - 0.0084 16.0 0.2 0.47 10.4 0.1 3.2 4 0 0 4 4 3 1 NACHT domain AAA_28 PF13521.6 KUM58702.1 - 0.011 15.9 0.0 0.085 13.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KUM58702.1 - 0.021 14.9 0.0 4.4 7.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KUM58702.1 - 0.04 14.1 0.0 0.31 11.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KUM58702.1 - 0.055 13.2 0.0 0.92 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KUM58702.1 - 0.086 12.4 0.1 1.6 8.2 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KUM58702.1 - 0.11 12.4 0.0 15 5.4 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 KUM58702.1 - 0.15 11.8 0.0 3.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 KUM58702.1 - 0.16 12.4 0.0 0.4 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NPP1 PF05630.11 KUM58703.1 - 4.3e-58 196.7 0.0 4.9e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Sugar_tr PF00083.24 KUM58704.1 - 6.5e-81 272.5 21.5 8e-81 272.2 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM58704.1 - 1.3e-14 53.9 58.1 2.8e-13 49.5 29.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2456 PF10445.9 KUM58704.1 - 0.3 11.2 4.5 4.6 7.4 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) DUF4646 PF15496.6 KUM58705.1 - 2.1e-06 28.4 0.0 1.7e-05 25.5 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) Erf4 PF10256.9 KUM58705.1 - 0.041 14.0 0.0 0.16 12.1 0.0 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Fungal_trans PF04082.18 KUM58706.1 - 2.2e-08 33.5 0.0 4.1e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KUM58707.1 - 5.4e-31 107.8 32.8 6.8e-31 107.5 32.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MASE2 PF05230.11 KUM58707.1 - 0.67 10.1 5.2 2.8 8.1 0.8 2.7 2 0 0 2 2 2 0 MASE2 domain PFK PF00365.20 KUM58708.1 - 8.7e-189 625.7 0.4 3.3e-103 344.9 0.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 KUM58708.1 - 0.073 12.7 0.1 0.31 10.7 0.1 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain XylR_N PF06505.11 KUM58708.1 - 0.13 12.0 0.2 4.1 7.2 0.0 2.6 2 0 0 2 2 2 0 Activator of aromatic catabolism SKG6 PF08693.10 KUM58709.1 - 0.02 14.3 1.7 0.036 13.5 1.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DNA_ligase_A_M PF01068.21 KUM58710.1 - 8.6e-24 84.3 0.0 2e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KUM58710.1 - 4.9e-15 56.3 0.0 1.3e-14 54.9 0.0 1.7 2 0 0 2 2 2 1 DNA ligase N terminus GEN1_C PF18380.1 KUM58710.1 - 0.13 13.2 0.3 17 6.4 0.1 2.5 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Fungal_trans PF04082.18 KUM58711.1 - 3.9e-10 39.2 0.6 6.5e-10 38.5 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM58711.1 - 6.1e-06 26.3 12.0 6.1e-06 26.3 12.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DJ-1_PfpI PF01965.24 KUM58712.1 - 1.2e-08 34.9 0.0 5.3e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KUM58712.1 - 0.023 14.4 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like polyprenyl_synt PF00348.17 KUM58713.1 - 1.5e-89 299.5 0.0 1.8e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase RNase_H2-Ydr279 PF09468.10 KUM58713.1 - 0.0011 19.2 0.2 0.0052 17.0 0.1 2.0 2 1 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain GatB_Yqey PF02637.18 KUM58713.1 - 0.12 12.2 1.7 0.32 10.9 1.7 1.7 1 0 0 1 1 1 0 GatB domain SEP PF08059.13 KUM58714.1 - 3.6e-25 88.3 0.1 6.4e-25 87.5 0.1 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KUM58714.1 - 4.4e-14 52.4 0.0 7.5e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KUM58714.1 - 3.6e-13 49.1 3.3 6.1e-13 48.4 3.3 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KUM58714.1 - 0.00046 19.8 0.3 0.00075 19.1 0.3 1.3 1 0 0 1 1 1 1 TAP C-terminal domain ANAPC8 PF04049.13 KUM58716.1 - 1e-51 174.7 0.0 2.9e-51 173.2 0.0 1.8 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 KUM58716.1 - 1.1e-21 75.7 8.5 0.00042 20.0 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KUM58716.1 - 1.7e-21 74.6 17.2 8e-05 22.6 0.0 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 KUM58716.1 - 9.6e-18 62.8 20.0 0.063 13.4 2.8 9.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 KUM58716.1 - 1.5e-14 53.4 19.5 0.0084 16.9 0.0 8.9 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 KUM58716.1 - 1.1e-11 44.2 1.6 2e-06 27.4 0.1 4.5 2 2 2 4 4 4 3 TPR repeat TPR_16 PF13432.6 KUM58716.1 - 1.6e-11 44.7 13.3 7e-05 23.4 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM58716.1 - 1.9e-10 40.8 16.9 0.083 13.1 0.2 6.4 7 0 0 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KUM58716.1 - 2.5e-09 37.1 10.6 0.00013 22.1 0.3 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KUM58716.1 - 2.9e-09 36.7 4.5 1.8 9.1 0.0 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KUM58716.1 - 4.1e-09 36.6 12.1 0.55 10.6 0.2 6.7 6 2 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KUM58716.1 - 6.4e-09 36.2 15.3 0.12 12.9 0.1 8.1 9 1 1 10 10 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 KUM58716.1 - 1.6e-07 30.9 10.2 0.27 11.3 0.1 6.5 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 KUM58716.1 - 5.9e-05 23.4 21.3 1.9 9.3 0.4 8.7 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 KUM58716.1 - 0.0011 18.2 11.9 0.0024 17.1 3.3 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.10 KUM58716.1 - 0.0081 15.2 0.1 7.6 5.4 0.0 3.0 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) HrpB1_HrpK PF09613.10 KUM58716.1 - 0.0098 15.5 0.1 0.045 13.4 0.0 2.1 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 KUM58716.1 - 0.39 10.7 14.9 3.3 7.7 0.5 6.5 6 1 1 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 KUM58716.1 - 0.39 11.1 1.5 46 4.6 0.0 4.2 5 0 0 5 5 4 0 PPR repeat TPR_4 PF07721.14 KUM58716.1 - 1.6 9.6 6.7 2.1 9.2 0.6 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat PHO4 PF01384.20 KUM58717.1 - 2.4e-110 368.7 12.4 2.9e-110 368.5 12.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family SpoVAB PF13782.6 KUM58717.1 - 0.83 10.0 10.2 0.084 13.2 1.6 3.1 3 0 0 3 3 3 0 Stage V sporulation protein AB Adeno_E3_CR2 PF02439.15 KUM58717.1 - 0.98 9.2 4.5 1.1 9.1 1.6 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 ParA PF10609.9 KUM58718.1 - 3.3e-85 285.5 0.1 1.1e-83 280.5 0.1 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KUM58718.1 - 3.5e-10 40.0 0.0 2.8e-09 37.1 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KUM58718.1 - 1.1e-06 28.2 0.0 5e-06 26.0 0.0 1.8 1 1 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 KUM58718.1 - 1.6e-05 24.9 0.3 0.00025 21.0 0.3 2.0 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 KUM58718.1 - 0.00021 20.6 0.8 0.00037 19.8 0.8 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 KUM58718.1 - 0.0006 19.4 0.3 0.0032 17.0 0.3 2.0 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 KUM58718.1 - 0.00077 19.1 0.2 0.0014 18.3 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KUM58718.1 - 0.0065 16.3 1.8 2.9 7.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KUM58718.1 - 0.0087 15.1 0.5 0.0087 15.1 0.5 1.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 KUM58718.1 - 0.07 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Fer4_NifH PF00142.18 KUM58718.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RsgA_GTPase PF03193.16 KUM58718.1 - 0.74 9.7 1.9 1.4 8.8 1.9 1.4 1 0 0 1 1 1 0 RsgA GTPase Glyco_transf_90 PF05686.12 KUM58719.1 - 7.3e-29 100.9 0.6 9.7e-29 100.5 0.6 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 p450 PF00067.22 KUM58720.1 - 1.1e-48 166.2 0.0 1.4e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 bZIP_1 PF00170.21 KUM58721.1 - 0.0037 17.3 8.2 0.0054 16.8 8.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor UPF0147 PF03685.13 KUM58721.1 - 0.071 13.2 0.3 0.1 12.6 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) DIT1_PvcA PF05141.12 KUM58722.1 - 1.5e-93 313.3 0.0 2.4e-93 312.6 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 KUM58722.1 - 6.8e-21 75.2 0.0 2e-20 73.7 0.0 1.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lon_C PF05362.13 KUM58724.1 - 3.5e-64 216.1 0.0 7.2e-64 215.1 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KUM58724.1 - 1.5e-33 116.5 0.0 3.2e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KUM58724.1 - 8.6e-22 78.0 0.0 1.9e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KUM58724.1 - 2.2e-07 30.9 0.0 4.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KUM58724.1 - 3e-06 27.1 0.0 7.6e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 KUM58724.1 - 5.3e-06 26.6 0.0 1.5e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 KUM58724.1 - 7.1e-06 25.2 0.2 1.6e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_22 PF13401.6 KUM58724.1 - 9.4e-06 25.9 0.1 0.00012 22.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KUM58724.1 - 0.00012 22.5 1.1 0.0009 19.7 0.1 2.6 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 KUM58724.1 - 0.00019 21.2 0.0 0.00056 19.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KUM58724.1 - 0.0031 18.1 0.7 0.027 15.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KUM58724.1 - 0.0059 16.6 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KUM58724.1 - 0.021 14.5 0.0 0.057 13.2 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein DNTTIP1_dimer PF18192.1 KUM58724.1 - 0.022 15.1 1.6 3 8.3 0.1 3.1 2 2 0 2 2 2 0 DNTTIP1 dimerisation domain AAA_30 PF13604.6 KUM58724.1 - 0.023 14.4 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KUM58724.1 - 0.048 12.8 0.0 0.56 9.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 KUM58724.1 - 0.061 13.2 0.2 0.56 10.1 0.0 2.4 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.22 KUM58724.1 - 0.064 13.6 0.0 0.21 12.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase DUF4276 PF14103.6 KUM58724.1 - 0.067 13.4 0.2 0.18 12.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) RsgA_GTPase PF03193.16 KUM58724.1 - 0.088 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 KUM58724.1 - 0.16 11.4 0.5 0.33 10.4 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region F-box-like_2 PF13013.6 KUM58724.1 - 0.16 11.9 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain ABC_tran PF00005.27 KUM58724.1 - 0.16 12.4 1.7 0.41 11.2 0.1 2.2 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 KUM58724.1 - 1.9 9.0 5.4 5.8 7.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF1282 PF06930.12 KUM58725.1 - 0.065 13.0 4.2 0.21 11.4 4.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Secretin PF00263.21 KUM58726.1 - 0.00047 19.9 0.3 5.2 6.7 0.0 3.5 3 0 0 3 3 3 2 Bacterial type II and III secretion system protein Dicistro_VP4 PF11492.8 KUM58726.1 - 0.083 12.9 0.2 65 3.6 0.0 3.7 4 0 0 4 4 4 0 Cricket paralysis virus, VP4 Neur_chan_memb PF02932.16 KUM58726.1 - 0.21 11.6 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rad4 PF03835.15 KUM58727.1 - 2.5e-34 118.1 0.0 6.7e-34 116.7 0.0 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KUM58727.1 - 7.2e-29 100.0 0.1 1.5e-28 99.0 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KUM58727.1 - 1.3e-14 53.8 0.0 2.8e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KUM58727.1 - 1.6e-13 51.4 0.2 1.6e-13 51.4 0.2 3.7 5 0 0 5 5 5 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KUM58727.1 - 0.0016 18.9 0.0 0.0046 17.4 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily Colicin_Pyocin PF01320.18 KUM58727.1 - 0.038 14.1 0.0 0.098 12.8 0.0 1.7 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein CoA_binding_2 PF13380.6 KUM58729.1 - 7.2e-28 97.4 0.0 8.6e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Mob1_phocein PF03637.17 KUM58730.1 - 4.7e-20 72.3 0.1 8.7e-20 71.4 0.1 1.4 1 0 0 1 1 1 1 Mob1/phocein family Nup88 PF10168.9 KUM58730.1 - 0.14 9.9 1.4 0.23 9.2 1.4 1.2 1 0 0 1 1 1 0 Nuclear pore component ORF11CD3 PF10549.9 KUM58730.1 - 0.36 11.0 1.4 12 6.1 0.2 2.6 2 0 0 2 2 2 0 ORF11CD3 domain ZapB PF06005.12 KUM58730.1 - 3.1 8.3 5.4 0.45 11.0 0.1 2.3 2 0 0 2 2 2 0 Cell division protein ZapB HIT PF01230.23 KUM58731.1 - 2.1e-24 86.1 0.1 3.6e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KUM58731.1 - 6.6e-06 26.6 0.1 9.6e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 KUM58731.1 - 0.037 13.7 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain HD_3 PF13023.6 KUM58732.1 - 2.6e-49 167.3 0.1 3.2e-49 167.0 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KUM58732.1 - 1.7e-11 44.2 0.1 2.2e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HAUS6_N PF14661.6 KUM58733.1 - 1.7e-09 37.6 0.0 2.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Trypan_PARP PF05887.11 KUM58733.1 - 7.8 6.5 12.9 21 5.1 12.9 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) BRO1 PF03097.18 KUM58734.1 - 1.1e-124 416.2 0.6 2.7e-124 414.9 0.6 1.6 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KUM58734.1 - 1e-75 254.8 15.5 1e-75 254.8 15.5 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV VGCC_beta4Aa_N PF12052.8 KUM58734.1 - 0.02 15.0 2.7 0.098 12.8 2.7 2.3 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DUF4564 PF15169.6 KUM58734.1 - 0.097 12.4 1.2 1.1 9.0 1.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4564) HCMV_UL139 PF12507.8 KUM58734.1 - 0.68 10.3 7.1 3.2 8.2 3.3 3.6 2 2 0 2 2 2 0 Human Cytomegalovirus UL139 protein cobW PF02492.19 KUM58735.1 - 1.3e-48 164.9 0.2 1.7e-48 164.5 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KUM58735.1 - 2.1e-05 24.5 0.1 0.13 12.1 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase CobW_C PF07683.14 KUM58735.1 - 0.00039 20.3 0.0 0.00081 19.3 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 KUM58735.1 - 0.0091 16.4 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KUM58735.1 - 0.014 15.5 0.0 0.032 14.3 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KUM58735.1 - 0.015 14.8 0.9 3.4 7.2 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 KUM58735.1 - 0.038 13.7 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 KUM58735.1 - 0.042 12.9 0.1 0.08 12.0 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KUM58735.1 - 0.043 14.3 0.1 0.079 13.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KUM58735.1 - 0.049 12.6 0.6 1.8 7.5 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Septin PF00735.18 KUM58735.1 - 0.07 12.4 0.4 11 5.2 0.1 2.2 2 0 0 2 2 2 0 Septin ATPase_2 PF01637.18 KUM58735.1 - 0.079 12.9 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KUM58735.1 - 0.085 12.9 0.2 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 KUM58735.1 - 0.086 12.6 2.6 1.3 8.7 2.6 2.2 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KUM58735.1 - 0.1 13.2 0.1 0.27 11.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 KUM58735.1 - 0.11 12.2 0.4 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KUM58735.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 KUM58735.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KUM58735.1 - 0.15 12.6 0.1 0.45 11.0 0.0 1.8 2 0 0 2 2 1 0 ABC transporter Pkinase_Tyr PF07714.17 KUM58736.1 - 5.1e-09 35.8 0.0 4.4e-08 32.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KUM58736.1 - 6.6e-09 35.5 0.0 7.9e-08 32.0 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain SAP30_Sin3_bdg PF13867.6 KUM58737.1 - 3.4e-09 36.9 0.1 7.1e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DnaJ_C PF01556.18 KUM58738.1 - 1.1e-35 123.0 0.0 1.5e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KUM58738.1 - 1.6e-22 79.4 3.9 2.8e-22 78.6 3.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KUM58738.1 - 5.1e-09 36.4 18.6 1e-08 35.4 18.6 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KUM58738.1 - 0.95 9.5 15.8 0.11 12.5 1.9 2.8 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KUM58738.1 - 3.8 7.6 6.5 9.4 6.3 5.5 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Thiolase_N PF00108.23 KUM58739.1 - 3e-92 308.6 0.7 4.9e-92 308.0 0.7 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KUM58739.1 - 5.5e-44 148.7 3.0 5.8e-44 148.7 1.4 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KUM58739.1 - 1.7e-06 27.8 2.8 4.4e-06 26.5 1.1 2.5 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KUM58739.1 - 0.067 13.0 2.8 0.19 11.6 0.1 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.27 KUM58740.1 - 1.5e-47 161.7 0.0 2.4e-47 161.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KUM58740.1 - 1.9e-37 128.6 12.3 3.5e-37 127.7 12.3 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KUM58740.1 - 4.7e-24 84.5 0.0 1.2e-23 83.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KUM58740.1 - 1e-20 73.6 0.0 2.7e-20 72.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KUM58740.1 - 7.2e-12 45.5 0.0 1.7e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KUM58740.1 - 3.6e-07 30.2 0.2 3.1e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KUM58740.1 - 4.6e-07 29.9 0.1 8.3e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KUM58740.1 - 0.0085 15.7 0.0 0.044 13.4 0.0 2.1 1 1 0 1 1 1 1 Ras family ABC_trans_aux PF03886.13 KUM58741.1 - 0.013 15.1 0.3 0.016 14.8 0.3 1.2 1 0 0 1 1 1 0 ABC-type transport auxiliary lipoprotein component FeS_assembly_P PF01883.19 KUM58742.1 - 4.6e-08 33.1 0.0 1.2e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Zip PF02535.22 KUM58743.1 - 1.7e-33 116.2 0.1 2.6e-33 115.7 0.1 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Amidohydro_1 PF01979.20 KUM58744.1 - 1.5e-16 60.7 0.0 1.9e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KUM58744.1 - 1.6e-10 41.1 0.8 2.2e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family GMC_oxred_N PF00732.19 KUM58745.1 - 8.3e-53 179.7 0.0 1.1e-52 179.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM58745.1 - 8.7e-38 130.1 0.0 1.3e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KUM58745.1 - 8.1e-07 28.5 0.2 0.01 14.9 0.1 2.4 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.12 KUM58745.1 - 0.00038 19.6 0.0 0.00057 19.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KUM58745.1 - 0.00054 20.1 0.1 0.0018 18.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM58745.1 - 0.0037 16.9 0.5 0.051 13.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM58745.1 - 0.0085 15.4 0.0 0.034 13.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KUM58745.1 - 0.018 14.4 0.2 0.84 8.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KUM58745.1 - 0.037 13.2 0.1 0.85 8.8 0.0 2.6 3 0 0 3 3 3 0 Thi4 family Pyr_redox PF00070.27 KUM58745.1 - 0.041 14.4 0.3 1.6 9.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KUM58746.1 - 1.3e-16 60.5 30.8 1.9e-16 59.9 30.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KUM58746.1 - 7.9e-10 38.7 5.6 7.9e-10 38.7 5.6 2.7 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 KUM58746.1 - 0.0027 16.6 6.3 0.0027 16.6 6.3 2.2 1 1 1 2 2 2 1 MFS_1 like family ABC2_membrane_5 PF13346.6 KUM58746.1 - 0.0092 15.5 5.1 0.0092 15.5 5.1 2.9 3 0 0 3 3 3 1 ABC-2 family transporter protein CPSF_A PF03178.15 KUM58747.1 - 1.3e-105 353.3 0.0 2.6e-105 352.3 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 KUM58747.1 - 2.1e-19 69.6 0.0 5.1e-18 65.0 0.0 2.5 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.16 KUM58748.1 - 5.8e-21 75.0 6.8 5.8e-21 75.0 6.8 2.5 2 1 0 3 3 3 1 LMBR1-like membrane protein DUF5134 PF17197.4 KUM58748.1 - 0.18 11.7 1.5 0.8 9.6 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) DUF3592 PF12158.8 KUM58748.1 - 1.4 8.9 0.0 1.4 8.9 0.0 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF3592) Glyco_hydro_3 PF00933.21 KUM58749.1 - 2.1e-68 231.1 0.0 2.8e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 KUM58749.1 - 0.00096 19.4 0.0 0.0032 17.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 KUM58749.1 - 0.0077 16.2 0.0 0.015 15.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_6 PF13480.7 KUM58749.1 - 0.075 13.2 0.0 0.31 11.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain NDT80_PhoG PF05224.12 KUM58750.1 - 2.5e-41 141.9 0.0 5.8e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Aldedh PF00171.22 KUM58751.1 - 1.6e-156 521.5 0.2 1.9e-156 521.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glucosamine_iso PF01182.20 KUM58752.1 - 7.7e-20 71.7 0.0 1.2e-19 71.2 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DPM3 PF08285.11 KUM58753.1 - 3.9e-28 97.5 1.9 2.7e-26 91.6 0.2 2.0 2 0 0 2 2 2 2 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Phage_holin_3_6 PF07332.11 KUM58753.1 - 4.1 7.5 7.7 5.6 7.0 0.3 2.3 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III UQ_con PF00179.26 KUM58755.1 - 5e-19 68.3 0.1 7.6e-19 67.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.23 KUM58756.1 - 4.5e-41 141.4 0.2 5.6e-41 141.1 0.2 1.1 1 0 0 1 1 1 1 Surface antigen Cyto_heme_lyase PF01265.17 KUM58757.1 - 8.2e-127 422.8 2.8 9.4e-127 422.6 2.8 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Fungal_trans_2 PF11951.8 KUM58758.1 - 4.8e-13 48.7 0.1 8.3e-13 47.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC1 PF03109.16 KUM58760.1 - 2.2e-21 76.3 0.1 2.1e-18 66.6 0.1 2.5 1 1 0 1 1 1 1 ABC1 family Raf1_HTH PF18579.1 KUM58760.1 - 0.011 15.5 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain RIO1 PF01163.22 KUM58760.1 - 0.017 14.7 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 KUM58760.1 - 0.19 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase adh_short PF00106.25 KUM58761.1 - 3.9e-06 26.4 0.1 4.6e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM58761.1 - 0.001 19.0 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KUM58761.1 - 0.024 14.2 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.6 KUM58761.1 - 0.053 13.4 0.1 0.063 13.2 0.1 1.2 1 0 0 1 1 1 0 NAD(P)H-binding KAP PF05804.12 KUM58762.1 - 0.0036 15.5 0.1 0.091 10.9 0.0 2.2 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) DUF383 PF04063.14 KUM58762.1 - 0.035 13.8 1.0 1.4 8.6 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF383) Spc7 PF08317.11 KUM58762.1 - 0.093 11.6 0.1 0.17 10.8 0.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein YuzL PF14115.6 KUM58762.1 - 0.18 12.3 0.1 0.38 11.3 0.1 1.6 1 0 0 1 1 1 0 YuzL-like protein EAP30 PF04157.16 KUM58763.1 - 1.1e-47 162.3 0.1 1.3e-47 162.1 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.7 KUM58763.1 - 0.02 14.8 0.1 0.086 12.7 0.0 2.0 3 0 0 3 3 3 0 MarR family HTH_6 PF01418.17 KUM58763.1 - 0.059 13.4 0.0 0.6 10.1 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain, rpiR family Ribosomal_L30_N PF08079.12 KUM58764.1 - 3.3e-26 91.3 12.8 5.4e-26 90.6 12.8 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KUM58764.1 - 1.8e-17 63.0 1.9 4.6e-17 61.6 1.9 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Pribosyltran PF00156.27 KUM58765.1 - 3.1e-06 26.8 0.0 5.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Acyl-CoA_dh_2 PF08028.11 KUM58766.1 - 7.3e-12 45.7 0.2 1.4e-11 44.8 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KUM58766.1 - 5.2e-06 26.6 0.0 1.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KUM58766.1 - 5.3e-06 27.1 0.0 8.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KUM58766.1 - 0.0015 18.7 0.7 0.0065 16.7 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain IBR PF01485.21 KUM58767.1 - 0.00081 19.6 5.4 0.00081 19.6 5.4 4.8 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain PRK PF00485.18 KUM58768.1 - 0.0027 17.5 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family KAP_NTPase PF07693.14 KUM58768.1 - 0.0099 15.1 0.0 0.017 14.4 0.0 1.4 1 1 0 1 1 1 1 KAP family P-loop domain Zeta_toxin PF06414.12 KUM58768.1 - 0.013 14.8 0.0 0.03 13.6 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.14 KUM58768.1 - 0.039 13.8 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GSCFA PF08885.11 KUM58768.1 - 0.06 13.0 0.0 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 GSCFA family AAA_16 PF13191.6 KUM58768.1 - 0.079 13.3 0.0 0.15 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Sun2_CC2 PF18580.1 KUM58768.1 - 0.088 13.0 0.2 0.66 10.2 0.0 2.3 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 MeaB PF03308.16 KUM58768.1 - 0.089 11.8 0.0 0.31 10.0 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KUM58768.1 - 0.093 13.3 0.0 0.25 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KUM58768.1 - 0.098 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KUM58768.1 - 0.12 13.0 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Signal peptide binding domain adh_short PF00106.25 KUM58769.1 - 1.1e-82 276.3 9.3 2.6e-45 154.3 0.7 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM58769.1 - 2.7e-65 220.2 6.2 8.5e-35 120.4 0.3 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM58769.1 - 3.3e-25 89.0 4.5 9.3e-12 45.2 0.1 2.5 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.19 KUM58769.1 - 1.6e-18 66.4 0.3 3.8e-08 32.9 0.1 2.5 1 1 1 2 2 2 2 MaoC like domain THF_DHG_CYH_C PF02882.19 KUM58769.1 - 0.00048 19.5 0.4 0.0014 18.0 0.4 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.23 KUM58769.1 - 0.017 15.2 1.2 3.5 7.7 1.1 2.8 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain F-box-like PF12937.7 KUM58770.1 - 0.00061 19.6 0.0 0.0018 18.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like UFD1 PF03152.14 KUM58771.1 - 1.9e-26 92.6 0.0 4e-21 75.3 0.0 3.3 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KUM58771.1 - 9.7e-07 28.9 0.1 4.1e-06 26.9 0.1 2.1 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-LYAR PF08790.11 KUM58771.1 - 0.025 14.5 1.7 1.5 8.8 0.0 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zinc_ribbon_4 PF13717.6 KUM58771.1 - 0.32 10.9 5.0 15 5.6 0.2 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Yip1 PF04893.17 KUM58772.1 - 9e-08 32.0 15.9 3.7e-06 26.8 8.8 2.4 2 1 0 2 2 2 2 Yip1 domain Hpt PF01627.23 KUM58773.1 - 1.4e-09 38.1 0.0 2.7e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Hpt domain NusB PF01029.18 KUM58773.1 - 0.065 13.5 0.1 0.065 13.5 0.1 2.4 2 1 0 2 2 2 0 NusB family CobT PF06213.12 KUM58773.1 - 0.37 10.1 11.5 0.67 9.3 11.5 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 KUM58773.1 - 0.47 9.2 3.2 0.4 9.4 3.2 1.1 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.9 KUM58773.1 - 2.7 8.1 20.9 1.6 8.8 13.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RNA_pol_Rpc4 PF05132.14 KUM58773.1 - 4.8 7.6 11.1 9.9 6.6 11.1 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 SspB PF04386.13 KUM58773.1 - 7.5 6.4 10.6 16 5.4 10.6 1.6 1 0 0 1 1 1 0 Stringent starvation protein B DUF913 PF06025.12 KUM58773.1 - 8.4 5.3 9.9 1.1 8.2 6.2 1.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) GNAT_acetyltr_2 PF13718.6 KUM58773.1 - 8.4 5.7 7.8 13 5.1 7.8 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 MFS_1 PF07690.16 KUM58775.1 - 7.7e-26 90.8 45.5 7.7e-26 90.8 45.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM58775.1 - 8.1e-07 28.2 12.1 8.1e-07 28.2 12.1 2.6 1 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KUM58775.1 - 0.00018 20.1 5.6 0.00018 20.1 5.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) LSM PF01423.22 KUM58777.1 - 1e-15 57.2 0.4 1.3e-15 56.8 0.4 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KUM58777.1 - 0.059 13.5 0.1 0.11 12.7 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain PGP_phosphatase PF09419.10 KUM58778.1 - 1.9e-60 203.3 0.0 2.3e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KUM58778.1 - 0.00074 19.5 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KUM58778.1 - 0.044 14.1 0.0 5.5 7.2 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase LcrR PF09621.10 KUM58778.1 - 0.059 12.8 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) MCU PF04678.13 KUM58779.1 - 5.6e-27 95.0 0.2 5.6e-27 95.0 0.2 1.7 2 0 0 2 2 2 1 Mitochondrial calcium uniporter Adaptin_binding PF10199.9 KUM58780.1 - 2.1e-19 70.3 0.4 5.9e-19 68.9 0.5 1.7 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Tom22 PF04281.13 KUM58780.1 - 0.1 12.4 0.4 0.22 11.3 0.4 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DnaB_2 PF07261.11 KUM58782.1 - 0.091 12.5 0.0 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Replication initiation and membrane attachment dsrm PF00035.26 KUM58783.1 - 0.0001 22.9 0.0 0.00073 20.2 0.0 2.2 2 0 0 2 2 2 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KUM58783.1 - 0.0069 16.6 0.2 0.022 15.0 0.2 1.8 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 Prenyltrans PF00432.21 KUM58784.1 - 8.4e-42 140.6 28.4 9.8e-12 44.4 0.8 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KUM58784.1 - 0.0028 16.8 0.0 0.36 9.9 0.0 2.3 2 0 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KUM58784.1 - 0.01 15.0 0.0 0.04 13.0 0.0 1.9 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain Pea-VEAacid PF08111.11 KUM58784.1 - 0.069 13.5 2.5 1.1 9.7 0.4 2.7 2 0 0 2 2 2 0 Pea-VEAacid family Zn_clus PF00172.18 KUM58785.1 - 0.004 17.3 7.7 0.0077 16.3 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.9 KUM58785.1 - 7 5.1 7.7 9.7 4.6 7.7 1.1 1 0 0 1 1 1 0 Macoilin family PTPLA PF04387.14 KUM58787.1 - 2e-56 190.2 4.6 3.3e-56 189.5 4.6 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Grg1 PF11034.8 KUM58788.1 - 2.4e-30 104.6 13.6 2.6e-30 104.4 13.6 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 DUF3176 PF11374.8 KUM58790.1 - 9.3e-33 112.6 1.5 9.3e-33 112.6 1.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) SH3_7 PF12914.7 KUM58791.1 - 0.08 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 SH3 domain of SH3b2 type Ank_2 PF12796.7 KUM58792.1 - 5.9e-45 151.8 0.1 1.2e-07 32.2 0.0 5.6 4 1 0 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM58792.1 - 5.9e-36 122.4 0.2 1.1e-05 25.8 0.0 9.1 5 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM58792.1 - 7.2e-31 105.9 5.1 1.4e-06 28.5 0.0 7.9 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM58792.1 - 2.1e-23 79.8 6.3 0.0023 18.3 0.0 10.8 12 0 0 12 12 12 4 Ankyrin repeat Ank PF00023.30 KUM58792.1 - 3.7e-21 74.6 11.9 0.0044 17.4 0.1 10.7 11 0 0 11 11 11 6 Ankyrin repeat FCD PF07729.12 KUM58792.1 - 0.071 13.5 0.7 13 6.2 0.1 3.5 2 1 1 3 3 3 0 FCD domain DUF3883 PF13020.6 KUM58794.1 - 0.022 14.8 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) Sulfotransfer_4 PF17784.1 KUM58794.1 - 0.061 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase domain Pyr_redox_2 PF07992.14 KUM58795.1 - 2.1e-36 125.7 0.0 3e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM58795.1 - 1.7e-14 54.1 0.5 3.9e-11 43.3 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM58795.1 - 1.1e-06 28.1 0.1 1.2e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KUM58795.1 - 2.9e-06 26.4 0.1 0.16 10.8 0.0 3.0 2 1 1 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.12 KUM58795.1 - 7.2e-06 25.3 0.0 0.0024 17.0 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 KUM58795.1 - 2.5e-05 24.4 0.0 0.0069 16.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KUM58795.1 - 0.00025 20.4 0.0 0.55 9.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KUM58795.1 - 0.00034 20.3 0.5 1.7 8.2 0.0 3.4 3 1 1 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 KUM58795.1 - 0.00067 19.0 0.0 0.48 9.6 0.0 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.6 KUM58795.1 - 0.0019 18.2 0.1 23 4.9 0.0 3.9 3 1 1 4 4 4 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KUM58795.1 - 0.0036 16.1 0.1 0.46 9.1 0.0 3.0 2 1 1 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 KUM58795.1 - 0.0042 16.4 0.0 0.031 13.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KUM58795.1 - 0.0096 16.2 0.1 5.3 7.3 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain GIDA PF01134.22 KUM58795.1 - 0.032 13.3 0.2 1.3 8.0 0.0 3.3 4 0 0 4 4 4 0 Glucose inhibited division protein A DUF1188 PF06690.11 KUM58795.1 - 0.083 12.4 0.1 0.18 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Semialdhyde_dh PF01118.24 KUM58795.1 - 0.11 12.9 0.3 6.2 7.3 0.0 3.0 2 1 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain DUF2920 PF11144.8 KUM58795.1 - 0.19 10.9 0.1 0.3 10.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) MFS_1 PF07690.16 KUM58796.1 - 6.4e-29 101.0 82.8 1.2e-21 77.0 45.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CFEM PF05730.11 KUM58798.1 - 8.3e-15 54.6 7.6 1.2e-14 54.1 7.6 1.2 1 0 0 1 1 1 1 CFEM domain MGC-24 PF05283.11 KUM58798.1 - 0.028 14.9 6.2 0.038 14.4 6.2 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3439 PF11921.8 KUM58798.1 - 1.9 8.5 10.6 0.35 10.8 6.7 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3439) Gly_transf_sug PF04488.15 KUM58799.1 - 2.2e-14 53.9 0.0 4.6e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Acyl_transf_3 PF01757.22 KUM58800.1 - 1.9e-44 152.2 32.7 2.3e-44 151.9 32.7 1.1 1 0 0 1 1 1 1 Acyltransferase family Glycolipid_bind PF06475.11 KUM58801.1 - 0.046 13.2 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative glycolipid-binding Sulfolobus_pRN PF05584.11 KUM58802.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein Rad52_Rad22 PF04098.15 KUM58803.1 - 1.2e-60 203.8 0.1 1.6e-60 203.4 0.1 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Lipid_DES PF08557.10 KUM58804.1 - 1.3e-13 50.2 1.2 2.5e-13 49.3 1.2 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Phage_sheath_1C PF17482.2 KUM58805.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 Phage tail sheath C-terminal domain Aa_trans PF01490.18 KUM58806.1 - 8.1e-80 268.5 28.3 9.4e-80 268.3 28.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Asn_synthase PF00733.21 KUM58810.1 - 5.4e-95 319.1 0.5 1.9e-55 189.0 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KUM58810.1 - 2.8e-39 133.8 0.0 4.8e-39 133.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KUM58810.1 - 2.3e-29 102.3 0.0 5e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KUM58810.1 - 2.4e-06 27.2 0.0 4.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KUM58810.1 - 0.0063 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 NAD synthase UQ_con PF00179.26 KUM58811.1 - 9.4e-43 145.2 0.0 9.7e-32 109.5 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UBA PF00627.31 KUM58812.1 - 6.5e-05 22.8 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.20 KUM58812.1 - 0.0017 18.5 0.5 0.0038 17.4 0.0 1.9 2 0 0 2 2 2 1 UBX domain CDC27 PF09507.10 KUM58812.1 - 0.49 9.7 34.0 0.18 11.2 31.9 1.3 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 Rtf2 PF04641.12 KUM58812.1 - 1 8.7 18.8 1.5 8.2 18.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger RR_TM4-6 PF06459.12 KUM58812.1 - 7.5 6.3 24.0 13 5.6 24.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Porin_3 PF01459.22 KUM58813.1 - 3.3e-75 253.0 5.4 3.7e-75 252.9 5.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin DnaJ PF00226.31 KUM58814.1 - 1e-12 48.0 0.1 1.7e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Ank_2 PF12796.7 KUM58815.1 - 6.9e-25 87.5 3.9 8.1e-11 42.4 0.8 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM58815.1 - 6.8e-17 61.6 2.6 0.00031 21.2 0.1 6.1 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM58815.1 - 3.1e-14 51.7 9.6 0.019 15.5 0.0 8.1 8 1 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 KUM58815.1 - 1.3e-12 47.6 8.6 0.00016 21.9 0.3 5.9 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KUM58815.1 - 9.2e-11 41.7 7.7 0.018 15.4 0.1 6.0 6 0 0 6 6 6 3 Ankyrin repeat F-box PF00646.33 KUM58815.1 - 5.7e-07 29.3 0.0 2.3e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KUM58815.1 - 2.3e-06 27.4 0.0 7.4e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KUM58815.1 - 0.031 14.2 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 F-box Peptidase_M24 PF00557.24 KUM58817.1 - 5.5e-43 147.1 0.1 7e-43 146.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 LZ_Tnp_IS66 PF13007.7 KUM58817.1 - 0.44 11.4 1.8 1 10.2 1.8 1.5 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain FA_desaturase PF00487.24 KUM58818.1 - 1.7e-27 96.9 11.8 2e-27 96.6 11.8 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Motile_Sperm PF00635.26 KUM58819.1 - 8.2e-26 90.0 0.2 1.6e-25 89.0 0.2 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 KUM58819.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF756 PF05506.12 KUM58819.1 - 0.14 13.1 0.0 0.34 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF756) CPSase_L_D2 PF02786.17 KUM58820.1 - 1e-106 355.1 0.0 1.8e-84 282.4 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KUM58820.1 - 1.4e-41 141.7 0.1 3.7e-41 140.3 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Dala_Dala_lig_C PF07478.13 KUM58820.1 - 1.4e-17 63.9 0.1 1.3e-07 31.4 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KUM58820.1 - 5.2e-17 61.9 0.0 3.4e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KUM58820.1 - 6.1e-12 45.4 0.0 8.4e-05 22.3 0.0 3.3 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KUM58820.1 - 0.00013 21.5 0.0 0.035 13.6 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 KUM58820.1 - 0.0021 17.9 0.1 0.78 9.5 0.0 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KUM58820.1 - 0.0047 16.5 0.0 0.87 9.2 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain SET PF00856.28 KUM58822.1 - 9.9e-14 52.1 0.1 5.9e-13 49.6 0.0 2.2 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 KUM58822.1 - 4.5e-09 36.3 10.2 4.5e-09 36.3 10.2 1.8 2 0 0 2 2 2 1 MYND finger HTH_35 PF13693.6 KUM58822.1 - 0.15 12.1 0.3 1.1 9.3 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding AAA PF00004.29 KUM58824.1 - 5.6e-54 182.1 0.0 3.6e-43 147.2 0.0 3.0 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KUM58824.1 - 1e-29 102.7 0.5 2.2e-29 101.7 0.5 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KUM58824.1 - 5.6e-14 51.7 0.6 7.4e-08 32.1 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KUM58824.1 - 4.7e-07 30.3 7.4 0.013 15.8 0.3 4.6 3 2 0 4 4 4 2 AAA ATPase domain AAA_2 PF07724.14 KUM58824.1 - 2e-06 28.1 0.0 0.096 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KUM58824.1 - 3.3e-06 27.1 0.1 0.0066 16.4 0.1 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KUM58824.1 - 1.3e-05 24.9 0.0 0.0089 15.8 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KUM58824.1 - 1.4e-05 25.7 0.5 0.17 12.4 0.3 3.4 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 KUM58824.1 - 2.1e-05 24.5 0.5 0.082 12.8 0.0 3.3 3 0 0 3 3 3 2 NACHT domain AAA_22 PF13401.6 KUM58824.1 - 3.8e-05 24.0 0.4 0.8 10.0 0.1 3.4 2 1 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KUM58824.1 - 7.3e-05 22.6 0.2 0.065 13.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 KUM58824.1 - 0.00041 20.4 0.1 1.1 9.3 0.0 3.2 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KUM58824.1 - 0.00052 19.4 0.0 0.19 11.0 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 KUM58824.1 - 0.0013 18.4 0.5 2.9 7.4 0.2 3.2 2 1 0 3 3 3 1 AAA domain PEX-2N PF09263.10 KUM58824.1 - 0.0017 18.6 0.5 0.15 12.4 0.6 3.0 2 1 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_33 PF13671.6 KUM58824.1 - 0.0034 17.6 0.1 0.15 12.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KUM58824.1 - 0.0047 17.2 0.0 1.8 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KUM58824.1 - 0.0048 16.9 0.0 2.2 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KUM58824.1 - 0.0059 15.9 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KUM58824.1 - 0.012 15.0 0.2 0.19 11.1 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KUM58824.1 - 0.019 15.4 0.0 8.5 6.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 KUM58824.1 - 0.021 15.2 0.1 0.29 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KUM58824.1 - 0.038 14.5 0.0 15 6.1 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 KUM58824.1 - 0.054 13.0 0.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KUM58824.1 - 0.087 12.7 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_17 PF13207.6 KUM58824.1 - 0.13 12.7 0.0 1.9 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KUM58824.1 - 0.13 11.9 0.0 5.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KUM58824.1 - 0.15 11.8 0.0 0.47 10.2 0.0 1.9 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 KUM58824.1 - 0.17 11.2 0.1 11 5.3 0.1 2.3 2 0 0 2 2 2 0 KaiC cobW PF02492.19 KUM58824.1 - 0.26 10.8 1.4 4.9 6.7 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.23 KUM58825.1 - 6.7e-103 342.6 0.0 1.1e-102 341.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KUM58825.1 - 5.2e-32 110.4 0.3 9.1e-32 109.6 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KUM58825.1 - 3.1e-20 72.4 0.9 7.7e-20 71.1 0.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KUM58825.1 - 5.4e-20 71.9 0.7 1.4e-19 70.6 0.7 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KUM58825.1 - 2.1e-07 30.5 0.0 1.7e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KUM58825.1 - 8.5e-07 29.1 0.0 2.1e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KUM58825.1 - 0.0016 18.2 0.0 0.005 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 KUM58825.1 - 0.017 15.0 0.0 0.059 13.2 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 KUM58825.1 - 0.031 14.9 0.2 0.23 12.1 0.2 2.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal PLDc_3 PF13918.6 KUM58825.1 - 0.14 11.8 0.1 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 PLD-like domain Sigma54_activat PF00158.26 KUM58825.1 - 0.14 11.8 0.0 0.86 9.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain EGF_CA PF07645.15 KUM58826.1 - 3.4e-05 23.9 7.7 3.4e-05 23.9 7.7 2.3 2 1 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.7 KUM58826.1 - 0.00035 20.7 6.8 0.00035 20.7 6.8 2.4 2 1 0 2 2 2 1 EGF domain cEGF PF12662.7 KUM58826.1 - 0.0018 18.2 2.2 0.0018 18.2 2.2 2.7 3 1 0 3 3 3 1 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KUM58826.1 - 0.0044 17.3 3.8 0.0044 17.3 3.8 2.6 2 2 0 2 2 2 1 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 KUM58826.1 - 0.013 15.8 2.2 0.013 15.8 2.2 2.0 2 0 0 2 2 2 0 Pvs28 EGF domain hEGF PF12661.7 KUM58826.1 - 1.8 9.3 9.0 0.25 12.1 2.8 2.6 2 0 0 2 2 2 0 Human growth factor-like EGF Carb_kinase PF01256.17 KUM58827.1 - 3.4e-36 125.0 1.3 6.6e-35 120.7 1.3 2.1 1 1 0 1 1 1 1 Carbohydrate kinase DUF4888 PF16229.5 KUM58827.1 - 0.0071 16.3 0.9 0.012 15.6 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4888) Enolase_C PF00113.22 KUM58829.1 - 1.8e-97 326.1 0.0 1.1e-52 179.1 0.0 2.1 2 0 0 2 2 2 2 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KUM58829.1 - 8.1e-50 168.4 0.1 1.5e-49 167.5 0.1 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KUM58829.1 - 0.00066 19.3 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like Mucin-like PF16058.5 KUM58829.1 - 0.057 13.5 12.0 0.054 13.6 10.3 1.8 2 0 0 2 2 2 0 Mucin-like MIOX PF05153.15 KUM58830.1 - 1.3e-124 414.8 2.6 1.7e-124 414.3 2.6 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase Cytochrom_C_2 PF01322.20 KUM58830.1 - 0.029 15.2 2.1 0.056 14.3 2.1 1.5 1 0 0 1 1 1 0 Cytochrome C' HD PF01966.22 KUM58830.1 - 0.076 13.2 2.7 0.51 10.6 0.0 2.9 2 2 1 4 4 4 0 HD domain GFO_IDH_MocA PF01408.22 KUM58831.1 - 2.3e-22 80.0 0.1 4.3e-22 79.2 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KUM58831.1 - 3.3e-06 27.1 0.0 5.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.15 KUM58831.1 - 0.069 13.3 0.0 0.22 11.7 0.0 1.9 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KRE1 PF17056.5 KUM58831.1 - 0.12 12.1 0.0 0.4 10.5 0.0 1.8 2 0 0 2 2 2 0 Killer toxin-resistance protein 1 AMP-binding PF00501.28 KUM58832.1 - 3.6e-95 319.1 0.0 4.2e-95 318.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM58832.1 - 5.7e-11 43.2 0.0 1.3e-10 42.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_S19 PF00203.21 KUM58833.1 - 1.2e-32 111.6 0.3 1.8e-32 111.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Glyco_hydro_28 PF00295.17 KUM58834.1 - 1.6e-123 411.9 22.0 1.8e-123 411.7 22.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NAD_binding_10 PF13460.6 KUM58835.1 - 7.8e-22 78.1 0.1 1.3e-21 77.3 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KUM58835.1 - 3.3e-05 23.5 0.0 5.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KUM58835.1 - 0.027 13.6 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Ribosomal_60s PF00428.19 KUM58836.1 - 1.7e-25 89.4 9.6 2.3e-25 89.0 9.6 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein SPT2 PF08243.11 KUM58837.1 - 7.2e-06 26.5 16.6 7.2e-06 26.5 16.6 2.0 2 1 0 2 2 2 1 SPT2 chromatin protein Thiolase_N PF00108.23 KUM58838.1 - 2.4e-63 213.9 0.3 3.5e-63 213.4 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KUM58838.1 - 5e-41 139.2 0.4 5e-41 139.2 0.4 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KUM58838.1 - 0.0039 16.8 2.9 0.0061 16.2 1.6 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 KUM58838.1 - 0.096 12.9 0.1 0.36 11.0 0.1 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal WLM PF08325.10 KUM58841.1 - 3e-52 177.5 0.1 7.9e-52 176.1 0.0 1.6 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.17 KUM58841.1 - 0.0034 17.5 0.1 0.0072 16.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 KUM58841.1 - 0.0037 17.1 0.0 0.0063 16.4 0.0 1.5 1 0 0 1 1 1 1 SprT-like family ubiquitin PF00240.23 KUM58841.1 - 0.069 12.9 0.1 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin family IBR PF01485.21 KUM58843.1 - 2.7e-09 37.1 18.5 1.3e-05 25.4 2.9 3.4 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KUM58843.1 - 0.00081 19.2 2.7 0.00081 19.2 2.7 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM58843.1 - 0.0012 18.6 1.9 0.0012 18.6 1.9 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KUM58843.1 - 0.0044 17.0 5.9 0.0044 17.0 5.9 3.6 3 2 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KUM58843.1 - 0.019 14.8 2.1 0.019 14.8 2.1 4.0 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KUM58843.1 - 0.037 14.4 5.0 0.037 14.4 5.0 3.8 3 1 1 4 4 4 0 Ring finger domain zf-RING_4 PF14570.6 KUM58843.1 - 1.3 8.8 14.3 11 5.9 0.4 4.0 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KUM58843.1 - 4 7.4 19.2 0.062 13.2 2.2 3.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 DZR PF12773.7 KUM58843.1 - 10 6.3 19.8 4.2 7.5 1.1 3.5 2 1 0 2 2 2 0 Double zinc ribbon Bac_rhamnosid6H PF17389.2 KUM58844.1 - 5.2e-89 298.8 0.0 7.2e-89 298.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KUM58844.1 - 1.5e-52 177.9 0.5 4.9e-52 176.2 0.0 2.0 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KUM58844.1 - 1.6e-17 63.4 0.0 3.6e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KUM58844.1 - 1.2e-16 60.2 0.0 2.4e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain CBM60 PF16841.5 KUM58844.1 - 0.096 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Ca-dependent carbohydrate-binding module xylan-binding Sugar_tr PF00083.24 KUM58845.1 - 6.5e-100 335.1 25.0 7.5e-100 334.9 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM58845.1 - 1.4e-26 93.2 38.9 2.7e-24 85.8 21.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 KUM58845.1 - 0.43 10.4 4.4 0.49 10.3 1.2 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain AA_permease_2 PF13520.6 KUM58848.1 - 9.9e-62 209.1 52.8 1.2e-61 208.9 52.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM58848.1 - 2.5e-34 118.7 48.1 3.4e-34 118.3 48.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.8 KUM58848.1 - 0.26 11.5 1.8 0.7 10.1 0.0 2.6 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 TMEM208_SND2 PF05620.11 KUM58848.1 - 0.73 9.6 5.7 3.3 7.5 0.1 3.1 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF2749 PF10907.8 KUM58848.1 - 3.9 7.7 0.0 3.9 7.7 0.0 3.7 4 1 1 5 5 5 0 Protein of unknown function (DUF2749) ACBP PF00887.19 KUM58849.1 - 1e-21 76.9 0.0 3.2e-21 75.3 0.0 1.9 2 0 0 2 2 2 1 Acyl CoA binding protein LAP1C PF05609.12 KUM58849.1 - 0.0046 16.1 0.9 0.0061 15.7 0.9 1.2 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) PI3K_1B_p101 PF10486.9 KUM58849.1 - 0.17 9.7 5.6 0.26 9.0 5.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Zip PF02535.22 KUM58849.1 - 1.9 7.6 5.1 2.7 7.1 5.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Sporozoite_P67 PF05642.11 KUM58849.1 - 9.8 4.1 7.4 13 3.7 7.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DASH_Ask1 PF08655.10 KUM58851.1 - 9.7e-30 102.3 0.4 2.1e-29 101.2 0.3 1.7 2 0 0 2 2 2 1 DASH complex subunit Ask1 HIG_1_N PF04588.13 KUM58852.1 - 2e-07 31.1 1.0 2e-07 31.1 1.0 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Med26 PF08711.11 KUM58853.1 - 1.6e-11 44.0 0.3 3.2e-11 43.1 0.3 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain RapH_N PF18801.1 KUM58853.1 - 0.28 11.3 0.9 32 4.7 0.0 2.6 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal Nup54 PF13874.6 KUM58854.1 - 1.4e-41 141.9 0.8 1e-40 139.1 0.0 2.2 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 KUM58854.1 - 7.6e-13 47.8 4.2 1.3e-12 47.0 4.2 1.4 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Nucleoporin_FG PF13634.6 KUM58854.1 - 4.5e-06 27.4 70.0 0.0015 19.4 18.2 3.2 1 1 2 3 3 2 2 Nucleoporin FG repeat region Fib_alpha PF08702.10 KUM58854.1 - 0.00012 22.3 1.2 0.00023 21.3 1.2 1.5 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family EzrA PF06160.12 KUM58854.1 - 0.047 11.9 5.2 0.061 11.5 4.1 1.6 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF745 PF05335.13 KUM58854.1 - 0.061 13.0 6.4 0.019 14.7 3.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF948 PF06103.11 KUM58854.1 - 0.063 13.5 0.3 1.5 9.1 0.1 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) V-SNARE_C PF12352.8 KUM58854.1 - 0.074 13.3 1.5 9 6.7 0.1 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Adhesin_P1_N PF18652.1 KUM58854.1 - 0.082 12.9 3.8 0.25 11.4 3.8 1.8 1 1 0 1 1 1 0 Adhesin P1 N-terminal domain Spc7 PF08317.11 KUM58854.1 - 0.25 10.2 7.5 0.26 10.1 6.9 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3867 PF12983.7 KUM58854.1 - 0.3 11.1 3.5 1.9 8.5 3.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3867) Spc24 PF08286.11 KUM58854.1 - 0.38 11.0 2.5 0.82 9.9 0.8 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 GAS PF13851.6 KUM58854.1 - 0.43 9.9 7.4 0.027 13.8 1.7 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2564 PF10819.8 KUM58854.1 - 0.52 10.7 5.2 0.21 12.0 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) Cor1 PF04803.12 KUM58854.1 - 4.5 7.5 9.1 0.11 12.8 1.9 2.0 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region CdvA PF18822.1 KUM58854.1 - 4.8 7.0 7.8 12 5.7 5.1 2.8 2 1 0 2 2 2 0 CdvA-like coiled-coil domain CHCH PF06747.13 KUM58855.1 - 1.5e-05 25.0 4.3 1.5e-05 25.0 4.3 2.6 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 KUM58855.1 - 0.00077 19.4 7.8 0.0033 17.4 2.3 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 KUM58855.1 - 0.073 13.4 9.4 0.62 10.4 2.2 2.9 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KUM58855.1 - 1.5 8.9 12.2 2.6 8.1 2.3 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Glyco_hydro_71 PF03659.14 KUM58856.1 - 5e-134 446.8 2.0 5e-134 446.8 2.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 Pkinase PF00069.25 KUM58858.1 - 1.8e-67 227.5 0.0 2.2e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM58858.1 - 2.1e-34 119.0 0.0 3.2e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KUM58858.1 - 1.1e-05 24.9 0.0 9.3e-05 21.9 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KUM58858.1 - 0.00027 20.0 0.2 0.00037 19.5 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KUM58858.1 - 0.00064 19.1 0.0 0.00093 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KUM58858.1 - 0.0043 16.7 0.1 0.0072 15.9 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KUM58858.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KUM58858.1 - 0.078 12.6 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SNF5 PF04855.12 KUM58860.1 - 6.9e-86 287.9 0.0 8.7e-86 287.6 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 KUM58860.1 - 7.1e-06 25.5 1.3 1.9e-05 24.2 1.3 1.8 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 KUM58860.1 - 0.11 12.3 4.6 0.13 12.0 1.2 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Abhydrolase_2 PF02230.16 KUM58861.1 - 4.5e-23 82.2 0.0 4.9e-17 62.5 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase NACHT PF05729.12 KUM58863.1 - 1.2e-10 41.5 0.1 2.2e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 NACHT domain zf-H2C2_2 PF13465.6 KUM58863.1 - 9.9e-09 35.3 18.7 7.5e-05 23.0 0.3 5.5 5 0 0 5 5 5 2 Zinc-finger double domain AAA_16 PF13191.6 KUM58863.1 - 0.0001 22.8 0.0 0.00027 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain zf-C2H2_4 PF13894.6 KUM58863.1 - 0.00013 22.5 27.9 0.0055 17.4 2.9 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KUM58863.1 - 0.00066 20.0 3.5 0.00066 20.0 3.5 4.5 4 1 0 4 4 3 3 Zinc finger, C2H2 type AAA_22 PF13401.6 KUM58863.1 - 0.0014 18.9 0.0 0.0041 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain zf-C2HE PF16278.5 KUM58863.1 - 0.0027 18.1 2.7 0.0027 18.1 2.7 2.9 2 1 1 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger zf-Di19 PF05605.12 KUM58863.1 - 0.0057 16.9 6.0 0.04 14.2 4.7 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KUM58863.1 - 0.0082 16.5 10.4 0.18 12.2 2.5 3.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type AAA PF00004.29 KUM58863.1 - 0.035 14.5 0.0 0.11 13.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-BED PF02892.15 KUM58863.1 - 0.12 12.4 7.1 3.6 7.7 0.1 3.4 3 0 0 3 3 3 0 BED zinc finger KAP_NTPase PF07693.14 KUM58863.1 - 0.15 11.2 0.0 0.4 9.9 0.0 1.8 1 0 0 1 1 1 0 KAP family P-loop domain zf-C2H2_jaz PF12171.8 KUM58863.1 - 0.49 10.7 20.3 0.18 12.1 1.3 4.0 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zinc-ribbons_6 PF07191.12 KUM58863.1 - 1.2 9.2 5.3 8.1 6.5 3.8 2.6 1 1 1 2 2 2 0 zinc-ribbons XFP_N PF09364.10 KUM58864.1 - 1.8e-174 579.7 0.0 2.4e-174 579.4 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 KUM58864.1 - 1.9e-83 278.9 0.0 3.3e-83 278.1 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 KUM58864.1 - 1.1e-81 272.8 0.0 1.7e-81 272.1 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase SPACA7 PF15307.6 KUM58865.1 - 0.061 13.6 0.1 0.073 13.3 0.1 1.2 1 0 0 1 1 1 0 Sperm acrosome-associated protein 7 DUF3632 PF12311.8 KUM58866.1 - 7.9e-17 62.2 7.5 1.3e-16 61.6 7.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) XFP_N PF09364.10 KUM58867.1 - 1.3e-16 60.4 0.0 2e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain Peptidase_M49 PF03571.15 KUM58868.1 - 7.7e-242 803.5 0.0 1e-241 803.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 bZIP_1 PF00170.21 KUM58869.1 - 0.13 12.4 2.9 0.19 11.8 2.9 1.2 1 0 0 1 1 1 0 bZIP transcription factor Pkinase PF00069.25 KUM58871.1 - 1.5e-16 60.6 0.0 3.9e-16 59.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM58871.1 - 7.1e-09 35.3 0.0 7.3e-08 32.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Aminotran_4 PF01063.19 KUM58872.1 - 3.8e-36 125.0 0.0 5.1e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV TACC_C PF05010.14 KUM58875.1 - 0.12 12.1 2.3 0.8 9.5 1.1 2.4 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BLOC1_2 PF10046.9 KUM58875.1 - 0.34 11.2 1.9 1.4 9.3 0.0 2.7 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF484 PF04340.12 KUM58875.1 - 0.76 9.4 3.9 0.65 9.6 2.2 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF484 RRM_1 PF00076.22 KUM58876.1 - 0.00043 20.0 0.0 0.00069 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WSD PF15613.6 KUM58876.1 - 0.049 14.1 0.1 0.054 14.0 0.1 1.1 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif RNA_POL_M_15KD PF02150.16 KUM58879.1 - 2.8e-11 43.1 1.6 2.8e-11 43.1 1.6 2.6 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit GFA PF04828.14 KUM58879.1 - 0.042 14.2 6.6 1.2 9.5 0.1 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme C1_1 PF00130.22 KUM58879.1 - 0.2 11.5 8.4 0.74 9.8 0.6 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) eIF3g PF12353.8 KUM58879.1 - 5 7.5 6.7 0.17 12.2 0.9 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Rotamase PF00639.21 KUM58880.1 - 5.8e-23 81.7 0.0 7.6e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KUM58880.1 - 1.3e-13 51.5 0.0 1.7e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KUM58880.1 - 1.4e-09 37.8 2.8 1.4e-09 37.8 2.8 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KUM58880.1 - 0.0002 22.2 0.0 0.00033 21.5 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain SET PF00856.28 KUM58881.1 - 6.8e-12 46.1 0.0 1.1e-09 38.9 0.0 2.8 2 0 0 2 2 2 2 SET domain FAM76 PF16046.5 KUM58881.1 - 0.0099 15.3 3.4 0.56 9.5 0.7 2.3 2 0 0 2 2 2 2 FAM76 protein Ribosomal_L14 PF00238.19 KUM58882.1 - 1.9e-46 157.1 1.9 2.2e-46 156.9 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Phage_antitermQ PF06530.12 KUM58882.1 - 0.026 14.4 0.1 0.038 13.9 0.1 1.4 1 1 0 1 1 1 0 Phage antitermination protein Q FlgH PF02107.16 KUM58882.1 - 0.027 14.1 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein DUF4777 PF16007.5 KUM58882.1 - 0.14 12.4 0.1 0.5 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) DEAD PF00270.29 KUM58883.1 - 1e-29 103.6 0.0 1.7e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM58883.1 - 4.2e-18 65.7 0.1 2e-17 63.5 0.1 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM58883.1 - 2.1e-05 24.6 0.0 9.5e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit COesterase PF00135.28 KUM58884.1 - 7.9e-72 242.8 0.1 9.3e-72 242.5 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KUM58884.1 - 0.00014 21.8 0.1 0.0022 17.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KUM58884.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family SNO PF01174.19 KUM58885.1 - 1.3e-54 185.0 0.0 1.3e-44 152.3 0.0 2.1 1 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KUM58885.1 - 3.1e-09 36.7 0.0 5.7e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KUM58885.1 - 0.0012 18.7 0.0 0.0088 15.8 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 KUM58885.1 - 0.015 14.9 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 DJ-1_PfpI PF01965.24 KUM58885.1 - 0.019 14.8 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family GATase_5 PF13507.6 KUM58885.1 - 0.052 12.6 0.0 0.93 8.5 0.0 2.1 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain RRM_1 PF00076.22 KUM58886.1 - 0.0005 19.8 0.0 0.00071 19.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ACPS PF01648.20 KUM58887.1 - 3.2e-11 43.3 0.0 1.4e-10 41.3 0.0 2.2 3 1 0 3 3 3 1 4'-phosphopantetheinyl transferase superfamily PH PF00169.29 KUM58888.1 - 5.4e-07 30.1 0.0 1.8e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 PH domain Anillin PF08174.11 KUM58888.1 - 4.7e-06 27.1 0.0 1.4e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Cell division protein anillin DUF829 PF05705.14 KUM58889.1 - 3.5e-52 177.7 0.1 4e-52 177.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) LIFR_N PF18207.1 KUM58890.1 - 0.13 12.7 0.0 1.1 9.7 0.0 2.3 3 0 0 3 3 3 0 Leukemia inhibitory factor receptor N-terminal domain Kelch_3 PF13415.6 KUM58891.1 - 2.2e-32 110.7 5.1 3.4e-07 30.4 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KUM58891.1 - 6.2e-32 109.4 3.6 3.1e-12 46.3 0.0 5.8 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_1 PF01344.25 KUM58891.1 - 5.4e-17 61.1 2.1 0.00027 20.5 0.0 6.6 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KUM58891.1 - 6.5e-17 61.1 2.4 0.0033 17.6 0.0 6.4 5 1 1 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KUM58891.1 - 5.8e-12 45.1 5.9 0.0005 19.9 0.1 6.4 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 KUM58891.1 - 3.2e-09 36.6 5.6 0.0042 17.0 0.0 6.2 6 1 0 6 6 6 3 Kelch motif Ank_2 PF12796.7 KUM58892.1 - 2.6e-120 393.2 13.8 6.7e-20 71.5 0.1 9.5 2 1 9 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM58892.1 - 2.9e-84 276.4 9.2 2e-10 41.0 0.0 12.6 5 2 10 15 15 14 13 Ankyrin repeats (many copies) Ank PF00023.30 KUM58892.1 - 2.2e-70 230.2 7.7 1.1e-06 28.8 0.0 15.0 13 1 1 14 14 14 14 Ankyrin repeat Ank_3 PF13606.6 KUM58892.1 - 4.8e-69 220.1 2.0 3e-05 24.1 0.0 16.0 16 0 0 16 16 16 14 Ankyrin repeat Ank_5 PF13857.6 KUM58892.1 - 1.9e-66 219.2 3.3 1.8e-05 24.9 0.0 14.2 4 2 10 14 14 14 13 Ankyrin repeats (many copies) Trp_ring PF18669.1 KUM58892.1 - 1.5e-06 28.3 0.0 46 4.3 0.0 8.3 9 0 0 9 9 9 0 Trimeric autotransporter adhesin Trp ring domain AAA_16 PF13191.6 KUM58892.1 - 4.6e-06 27.1 0.1 1.7e-05 25.3 0.1 1.9 2 0 0 2 2 1 1 AAA ATPase domain NACHT PF05729.12 KUM58892.1 - 0.00011 22.2 0.3 0.00031 20.7 0.3 1.8 1 1 0 1 1 1 1 NACHT domain DUF5049 PF16468.5 KUM58892.1 - 0.00014 21.6 9.6 76 3.3 0.0 9.2 11 0 0 11 11 11 0 Domain of unknown function (DUF5049) DUF4350 PF14258.6 KUM58892.1 - 0.0006 20.2 0.2 41 4.7 0.0 5.6 6 0 0 6 6 5 0 Domain of unknown function (DUF4350) DUF4988 PF16378.5 KUM58892.1 - 0.0021 17.8 0.0 1 9.0 0.0 3.7 2 1 1 3 3 3 1 Domain of unknown function DUF5338 PF17273.2 KUM58892.1 - 0.0033 17.5 0.0 43 4.3 0.0 5.3 6 0 0 6 6 6 0 Family of unknown function (DUF5338) DUF773 PF05600.12 KUM58892.1 - 0.0084 14.9 0.0 0.024 13.4 0.0 1.7 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 ANT PF03374.14 KUM58892.1 - 0.016 15.5 0.0 20 5.5 0.0 4.0 1 1 1 4 4 4 0 Phage antirepressor protein KilAC domain YfmQ PF10787.9 KUM58892.1 - 0.11 12.2 0.2 1.4e+02 2.2 0.0 4.4 3 2 3 7 7 6 0 Uncharacterised protein from bacillus cereus group DUF1737 PF08410.10 KUM58892.1 - 0.19 11.6 0.5 40 4.2 0.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1737) ZZ PF00569.17 KUM58892.1 - 0.95 9.3 10.0 0.048 13.5 3.8 2.0 2 0 0 2 2 2 0 Zinc finger, ZZ type PNP_UDP_1 PF01048.20 KUM58893.1 - 2.3e-11 43.4 0.1 7.6e-11 41.7 0.1 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily DUF2284 PF10050.9 KUM58893.1 - 0.0092 15.7 0.8 0.014 15.1 0.8 1.2 1 0 0 1 1 1 1 Predicted metal-binding protein (DUF2284) Transp_cyt_pur PF02133.15 KUM58895.1 - 3.5e-153 510.5 42.1 4.1e-153 510.3 42.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PI-PLC-X PF00388.19 KUM58896.1 - 6.5e-60 200.9 0.0 1.2e-59 200.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KUM58896.1 - 3.4e-43 146.6 0.1 7.5e-42 142.3 0.2 2.5 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_8 PF13833.6 KUM58896.1 - 0.0054 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_like PF09279.11 KUM58896.1 - 0.0096 16.4 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.17 KUM58896.1 - 0.045 13.5 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family EF-hand_1 PF00036.32 KUM58896.1 - 0.12 12.0 0.1 0.47 10.1 0.1 2.1 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 KUM58896.1 - 0.22 11.5 0.7 0.76 9.9 0.2 2.2 2 0 0 2 2 2 0 EF-hand domain ATG27 PF09451.10 KUM58898.1 - 4 7.2 7.9 5.4 6.8 7.9 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 Urb2 PF10441.9 KUM58899.1 - 2e-63 214.0 2.2 4.2e-63 213.0 0.1 2.5 2 0 0 2 2 2 1 Urb2/Npa2 family Elicitin PF00964.17 KUM58899.1 - 0.11 12.6 0.9 0.44 10.7 0.9 2.0 1 0 0 1 1 1 0 Elicitin DUF3176 PF11374.8 KUM58900.1 - 5.3e-33 113.4 0.4 1.4e-32 112.1 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Antimicrobial25 PF16839.5 KUM58900.1 - 0.044 13.9 1.1 0.15 12.1 1.1 1.9 1 0 0 1 1 1 0 Nematode antimicrobial peptide DUF2786 PF10979.8 KUM58901.1 - 2.1e-16 59.5 0.2 5.7e-16 58.2 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) Bravo_FIGEY PF13882.6 KUM58901.1 - 0.32 12.4 0.3 0.32 12.4 0.3 2.5 2 1 0 2 2 2 0 Bravo-like intracellular region NmrA PF05368.13 KUM58902.1 - 1.2e-54 185.3 0.7 1.5e-54 185.1 0.7 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM58902.1 - 1.4e-17 64.2 0.4 2e-17 63.7 0.4 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KUM58902.1 - 1.4e-06 27.6 0.0 2.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KUM58902.1 - 0.00019 21.0 0.1 0.00031 20.3 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KUM58902.1 - 0.0018 18.5 0.2 0.0036 17.6 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 KUM58902.1 - 0.0028 17.1 0.1 0.0054 16.2 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KUM58902.1 - 0.011 15.6 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 KR domain ADH_zinc_N PF00107.26 KUM58902.1 - 0.039 13.9 0.4 0.35 10.9 0.7 2.1 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 KUM58902.1 - 0.049 14.1 0.2 0.11 12.9 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KUM58902.1 - 0.092 13.5 0.1 0.18 12.5 0.1 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase A_deaminase PF00962.22 KUM58903.1 - 2e-13 50.4 0.0 2.4e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase RVT_1 PF00078.27 KUM58905.1 - 0.0028 17.2 0.1 0.0092 15.5 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-F_leu_zip PF10473.9 KUM58905.1 - 0.024 14.7 0.5 0.27 11.3 0.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_int_SAM_4 PF13495.6 KUM58905.1 - 0.057 13.9 0.2 0.52 10.8 0.1 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Snapin_Pallidin PF14712.6 KUM58905.1 - 0.072 13.5 0.1 16 6.0 0.0 3.5 3 0 0 3 3 3 0 Snapin/Pallidin ABC_tran_CTD PF16326.5 KUM58905.1 - 0.089 13.0 0.4 2.2 8.6 0.1 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain GreA_GreB_N PF03449.15 KUM58905.1 - 0.95 9.7 7.0 18 5.6 0.3 3.8 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal Pox_A_type_inc PF04508.12 KUM58905.1 - 3.4 7.7 7.4 9.5 6.3 0.3 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Aldedh PF00171.22 KUM58906.1 - 2.3e-143 478.1 0.0 2.7e-143 477.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.16 KUM58909.1 - 1.7e-29 102.9 39.2 2.7e-28 98.9 36.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 KUM58909.1 - 0.017 14.9 0.6 0.058 13.2 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Hexapep PF00132.24 KUM58910.1 - 3.6e-07 29.7 5.6 0.052 13.3 0.1 3.2 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KUM58910.1 - 0.00012 22.5 0.0 0.00022 21.6 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KUM58910.1 - 0.00053 19.0 0.4 0.0051 15.8 0.3 2.3 1 1 1 2 2 2 1 L-fucokinase 2OG-FeII_Oxy PF03171.20 KUM58911.1 - 6.1e-15 55.6 0.0 1.1e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KUM58911.1 - 2.6e-13 50.8 0.0 7.8e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Epimerase PF01370.21 KUM58912.1 - 4.5e-17 62.3 0.0 8e-17 61.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM58912.1 - 1.1e-10 41.4 0.0 1.5e-09 37.7 0.1 2.6 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KUM58912.1 - 4.4e-10 39.0 0.0 5.6e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KUM58912.1 - 1.7e-07 30.7 0.0 0.00026 20.3 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KUM58912.1 - 6.8e-06 25.4 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KUM58912.1 - 0.00054 19.9 0.0 0.0015 18.5 0.0 1.7 2 1 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 KUM58912.1 - 0.00093 19.2 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KUM58912.1 - 0.00094 18.7 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KUM58912.1 - 0.029 13.5 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_114 PF03537.13 KUM58913.1 - 2.3e-83 279.1 2.4 4e-81 271.7 0.9 2.1 2 0 0 2 2 2 2 Glycoside-hydrolase family GH114 Myc_N PF01056.18 KUM58913.1 - 0.059 13.3 5.9 0.087 12.7 5.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TraD_N PF12615.8 KUM58913.1 - 0.086 13.6 0.1 3 8.7 0.0 2.8 2 1 1 3 3 3 0 F sex factor protein N terminal RXT2_N PF08595.11 KUM58913.1 - 0.18 11.8 2.5 0.32 11.0 2.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal SLAIN PF15301.6 KUM58913.1 - 0.2 10.9 5.3 0.31 10.2 5.3 1.3 1 0 0 1 1 1 0 SLAIN motif-containing family NOA36 PF06524.12 KUM58913.1 - 0.21 10.9 11.1 0.34 10.2 11.1 1.3 1 0 0 1 1 1 0 NOA36 protein DUF913 PF06025.12 KUM58913.1 - 0.41 9.6 3.3 0.58 9.1 3.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Sporozoite_P67 PF05642.11 KUM58913.1 - 0.52 8.3 12.0 0.74 7.8 12.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.12 KUM58913.1 - 0.59 9.5 10.7 0.86 9.0 10.7 1.2 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 KUM58913.1 - 0.64 8.7 4.6 0.87 8.3 4.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Cwf_Cwc_15 PF04889.12 KUM58913.1 - 0.65 9.7 12.1 2.1 8.0 11.4 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 KUM58913.1 - 0.73 10.2 3.9 1.6 9.2 3.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 KUM58913.1 - 1 9.8 11.2 0.6 10.5 8.7 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 KUM58913.1 - 1.1 7.3 7.4 1.4 6.9 7.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Med13_C PF06333.12 KUM58913.1 - 1.4 8.1 8.9 0.43 9.8 6.1 1.5 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain SURF2 PF05477.11 KUM58913.1 - 1.9 8.1 5.2 3.1 7.4 5.2 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Nop14 PF04147.12 KUM58913.1 - 2.2 6.4 9.9 2.8 6.0 9.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 KUM58913.1 - 7 6.0 8.4 14 5.0 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Med3 PF11593.8 KUM58913.1 - 7.4 5.6 9.9 1.6 7.8 6.3 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Glyco_hydro_71 PF03659.14 KUM58914.1 - 1.4e-129 432.2 4.5 1.6e-129 432.0 4.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 PAPA-1 PF04795.12 KUM58915.1 - 2.4e-32 111.6 8.1 2.4e-32 111.6 8.1 3.7 4 0 0 4 4 4 1 PAPA-1-like conserved region Mus7 PF09462.10 KUM58916.1 - 8.3e-205 682.2 0.0 1.1e-204 681.8 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family SRA1 PF07304.11 KUM58917.1 - 7e-14 51.8 0.0 7e-14 51.8 0.0 3.4 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 KUM58917.1 - 1.2e-08 35.5 7.1 0.87 10.6 0.1 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Sec16_C PF12931.7 KUM58917.1 - 0.00064 19.5 0.0 0.0081 15.8 0.0 2.4 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 ANAPC4_WD40 PF12894.7 KUM58917.1 - 0.0015 18.8 0.5 0.019 15.3 0.1 3.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Prp18 PF02840.15 KUM58917.1 - 0.043 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Prp18 domain Pex14_N PF04695.13 KUM58918.1 - 1.1e-44 152.8 5.3 1.1e-44 152.8 5.3 2.9 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region B12D PF06522.11 KUM58919.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.22 KUM58920.1 - 1e-16 60.5 0.0 1.6e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KUM58920.1 - 0.0099 16.0 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 KUM58920.1 - 0.029 14.4 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 Mito_carr PF00153.27 KUM58923.1 - 4.3e-31 106.7 0.1 1.6e-17 63.2 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein TAF8_C PF10406.9 KUM58924.1 - 7.1e-20 71.3 0.0 1.6e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KUM58924.1 - 6e-09 35.8 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated PAP2 PF01569.21 KUM58924.1 - 0.16 11.7 0.1 0.36 10.6 0.1 1.5 1 0 0 1 1 1 0 PAP2 superfamily Mitochondr_Som1 PF11093.8 KUM58925.1 - 2e-23 82.1 0.0 2.5e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Rad51 PF08423.11 KUM58926.1 - 8.3e-07 28.5 0.1 7.4e-05 22.1 0.0 2.2 2 1 0 2 2 2 2 Rad51 PALP PF00291.25 KUM58927.1 - 4.3e-72 243.0 0.4 5.2e-72 242.7 0.4 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KUM58927.1 - 0.041 13.2 0.1 0.065 12.5 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IlvN PF07991.12 KUM58928.1 - 4e-45 153.4 0.0 6e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KUM58928.1 - 2.7e-39 134.7 0.0 4.3e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 KUM58928.1 - 0.048 13.8 0.0 0.086 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2OG-FeII_Oxy_2 PF13532.6 KUM58929.1 - 2.8e-25 89.7 0.0 5e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 KUM58929.1 - 1.8e-24 86.9 0.0 9.9e-24 84.5 0.0 2.1 1 1 0 1 1 1 1 Isochorismatase family GST_C_2 PF13410.6 KUM58929.1 - 0.0026 17.7 0.1 0.0063 16.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Lipase_GDSL_2 PF13472.6 KUM58930.1 - 1.3e-11 45.2 0.3 1.6e-11 45.0 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KUM58930.1 - 2e-08 34.5 0.0 2.5e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ECH_1 PF00378.20 KUM58931.1 - 1.8e-34 119.2 0.0 3.9e-34 118.1 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KUM58931.1 - 4.7e-26 92.1 0.0 7.8e-25 88.1 0.0 1.8 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase HSP20 PF00011.21 KUM58932.1 - 9.5e-19 67.4 0.1 8.2e-18 64.4 0.1 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KUM58932.1 - 2.5e-07 30.1 0.0 6.5e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Tfb5 PF06331.12 KUM58933.1 - 8.4e-22 76.9 1.6 1e-21 76.6 1.6 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 UQ_con PF00179.26 KUM58934.1 - 1.1e-37 128.7 0.0 1.5e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KUM58934.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Oxidored_FMN PF00724.20 KUM58935.1 - 1.1e-88 297.8 0.0 1.2e-88 297.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.18 KUM58936.1 - 1.1e-23 83.7 0.2 1.7e-23 83.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SLAC1 PF03595.17 KUM58937.1 - 6.6e-55 186.6 34.5 7.5e-55 186.5 34.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TPR_12 PF13424.6 KUM58938.1 - 2e-34 117.7 10.5 2.2e-12 47.1 0.2 5.7 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KUM58938.1 - 2.4e-21 74.9 18.2 0.00054 19.7 0.1 7.8 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.6 KUM58938.1 - 1.5e-05 24.7 7.6 0.038 14.0 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KUM58938.1 - 3.6e-05 23.7 3.2 0.78 10.1 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KUM58938.1 - 6e-05 22.6 8.4 6e-05 22.6 8.4 2.1 2 1 0 2 2 2 1 MalT-like TPR region TPR_1 PF00515.28 KUM58938.1 - 0.00029 20.5 4.2 0.23 11.3 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KUM58938.1 - 0.00047 20.1 7.2 0.16 12.1 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KUM58938.1 - 0.0061 17.0 4.9 4.7 7.8 0.2 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM58938.1 - 0.0064 16.7 4.2 1.6 9.0 0.1 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 KUM58938.1 - 0.0078 15.9 0.4 4.6 6.9 0.1 2.7 2 1 1 3 3 3 2 26S proteasome subunit RPN7 TPR_16 PF13432.6 KUM58938.1 - 0.014 16.1 4.7 2.5 8.8 0.0 4.2 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KUM58938.1 - 0.076 13.7 10.1 1.6 9.5 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KUM58938.1 - 0.35 11.8 10.8 17 6.5 0.0 5.9 6 1 1 7 7 6 0 Tetratricopeptide repeat 2OG-FeII_Oxy PF03171.20 KUM58939.1 - 5.4e-13 49.3 0.0 1.1e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KUM58939.1 - 4.5e-12 46.8 0.0 2.5e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_hydro_43 PF04616.14 KUM58940.1 - 6.6e-34 117.5 3.5 8.4e-34 117.2 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.18 KUM58941.1 - 1.8e-14 53.4 0.0 3.9e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cu_amine_oxid PF01179.20 KUM58942.1 - 1.5e-146 488.5 0.2 5.2e-144 480.2 0.2 2.0 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KUM58942.1 - 0.00022 21.6 0.0 0.00043 20.6 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KUM58942.1 - 0.026 14.8 0.1 0.057 13.7 0.1 1.6 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain AA_permease_2 PF13520.6 KUM58943.1 - 1.5e-66 225.0 49.0 1.7e-66 224.8 49.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM58943.1 - 5.7e-19 68.1 39.3 9e-19 67.4 39.3 1.2 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 KUM58944.1 - 1.8e-55 188.4 0.4 2.5e-55 187.9 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain T2SSF PF00482.23 KUM58944.1 - 0.11 12.4 0.6 0.55 10.2 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F MPC PF03650.13 KUM58945.1 - 2.3e-49 166.1 0.3 3e-49 165.7 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF2863 PF11062.8 KUM58945.1 - 0.096 11.1 1.4 0.73 8.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2863) Glyco_hydro_28 PF00295.17 KUM58946.1 - 9e-50 169.6 6.4 1.9e-49 168.5 6.4 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 CBP4 PF07960.11 KUM58947.1 - 7.6e-27 93.7 2.7 1.1e-26 93.2 2.7 1.2 1 0 0 1 1 1 1 CBP4 Sel1 PF08238.12 KUM58949.1 - 9e-47 156.5 24.0 2.8e-08 34.2 0.1 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_20 PF14561.6 KUM58949.1 - 0.27 11.6 1.1 0.89 9.9 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Zn_clus PF00172.18 KUM58950.1 - 1.2e-07 31.7 8.8 1.2e-07 31.7 8.8 2.8 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KUM58950.1 - 1.8e-07 31.2 13.2 0.0016 18.8 5.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KUM58950.1 - 0.00014 22.1 10.8 0.0036 17.7 4.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain Fungal_trans PF04082.18 KUM58950.1 - 0.0057 15.7 0.0 0.0089 15.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 KUM58950.1 - 0.022 15.5 3.6 0.022 15.5 3.6 3.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 KUM58950.1 - 0.084 13.3 5.8 0.45 11.0 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type MGC-24 PF05283.11 KUM58951.1 - 0.46 10.9 7.2 0.68 10.4 7.2 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pkinase PF00069.25 KUM58953.1 - 6.1e-05 22.5 0.0 0.00017 21.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KUM58953.1 - 0.00021 21.3 0.0 0.00065 19.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KUM58953.1 - 0.018 14.3 0.0 0.063 12.6 0.0 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase GST_N_3 PF13417.6 KUM58955.1 - 4.4e-10 39.8 0.0 8.1e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KUM58955.1 - 1.5e-08 34.8 0.0 2.8e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KUM58955.1 - 2.3e-08 33.9 0.0 5.7e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KUM58955.1 - 3.4e-08 33.7 0.0 6.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KUM58955.1 - 2.6e-07 30.7 0.0 4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KUM58955.1 - 3.5e-07 30.3 0.0 5.3e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ctr PF04145.15 KUM58956.1 - 5.4e-32 111.5 0.1 6.8e-32 111.1 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Ferric_reduct PF01794.19 KUM58957.1 - 1.2e-20 73.9 13.7 2.5e-20 72.9 13.7 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KUM58957.1 - 9.3e-20 70.7 0.0 2e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KUM58957.1 - 9.3e-19 68.1 0.0 1.9e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF1687 PF07955.11 KUM58958.1 - 2.1e-26 92.9 0.0 3.3e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Pkinase PF00069.25 KUM58959.1 - 1.4e-59 201.6 0.0 1.4e-58 198.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM58959.1 - 2.9e-28 98.9 0.4 1.6e-19 70.2 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KUM58959.1 - 0.0003 21.4 0.6 0.001 19.7 0.6 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 KUM58959.1 - 0.0023 17.9 2.7 0.39 10.6 0.0 3.3 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KUM58959.1 - 0.0033 16.8 0.7 0.027 13.8 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 KUM58959.1 - 0.026 13.5 0.0 0.046 12.7 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KUM58959.1 - 0.089 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AATase PF07247.12 KUM58960.1 - 4.4e-17 61.8 0.0 4.5e-16 58.5 0.0 2.0 1 1 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.16 KUM58960.1 - 0.0038 17.1 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 KUM58960.1 - 0.22 10.2 0.0 0.86 8.2 0.0 1.9 2 0 0 2 2 2 0 Condensation domain LigB PF02900.18 KUM58961.1 - 6.3e-31 107.4 0.0 7.4e-30 103.9 0.0 1.9 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase L51_S25_CI-B8 PF05047.16 KUM58962.1 - 1e-12 47.7 0.0 1.3e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Abhydrolase_2 PF02230.16 KUM58963.1 - 1.1e-55 188.8 0.0 1.4e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KUM58963.1 - 8.9e-07 28.4 0.0 0.085 12.1 0.0 3.2 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KUM58963.1 - 2e-06 27.5 0.1 6.1e-05 22.6 0.0 2.4 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KUM58963.1 - 6.1e-05 22.8 0.1 0.00026 20.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KUM58963.1 - 0.00012 22.8 0.0 0.00014 22.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KUM58963.1 - 0.0017 18.1 0.0 0.0039 16.9 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 KUM58963.1 - 0.0061 16.5 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydro_lipase PF04083.16 KUM58963.1 - 0.011 15.3 0.0 2.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF2920 PF11144.8 KUM58963.1 - 0.014 14.6 0.0 0.24 10.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.13 KUM58963.1 - 0.019 14.8 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 KUM58963.1 - 0.043 12.5 0.0 0.065 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.18 KUM58963.1 - 0.047 13.2 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF676 PF05057.14 KUM58963.1 - 0.063 12.8 0.0 9 5.7 0.0 2.2 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Esterase PF00756.20 KUM58963.1 - 0.066 12.8 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative esterase PGAP1 PF07819.13 KUM58963.1 - 0.093 12.4 0.0 0.21 11.3 0.0 1.7 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 KUM58963.1 - 0.097 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1581 PF07619.11 KUM58963.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) LIP PF03583.14 KUM58963.1 - 0.12 11.7 0.0 4.5 6.5 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase DUF2974 PF11187.8 KUM58963.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 KUM58963.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 3) Pyr_redox_2 PF07992.14 KUM58964.1 - 2.2e-16 60.0 0.0 5.9e-11 42.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM58964.1 - 0.0024 17.1 0.0 0.033 13.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KUM58964.1 - 0.0045 16.1 0.0 1 8.3 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KUM58964.1 - 0.0046 16.2 0.1 2.1 7.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KUM58964.1 - 0.0065 15.2 0.0 0.023 13.4 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KUM58964.1 - 0.068 13.2 0.1 8.3 6.4 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding ubiquitin PF00240.23 KUM58966.1 - 2.8e-24 84.7 0.0 3.4e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KUM58966.1 - 1.6e-12 47.0 0.0 2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KUM58966.1 - 0.0016 18.9 0.0 0.0051 17.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KUM58966.1 - 0.028 14.3 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Pkinase PF00069.25 KUM58967.1 - 0.00075 18.9 0.0 0.0013 18.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain DUF3824 PF12868.7 KUM58969.1 - 8.1e-10 39.5 4.6 8.1e-10 39.5 4.6 8.8 3 2 3 7 7 7 2 Domain of unknwon function (DUF3824) Phosphoesterase PF04185.14 KUM58970.1 - 2.7e-63 214.3 0.9 7.5e-63 212.9 0.9 1.6 1 1 0 1 1 1 1 Phosphoesterase family Sugar_tr PF00083.24 KUM58971.1 - 1.8e-83 280.9 31.0 2.1e-83 280.7 31.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM58971.1 - 1.1e-27 96.9 27.9 1.4e-26 93.3 25.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM58971.1 - 0.00069 18.2 3.3 0.00069 18.2 3.3 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PalH PF08733.10 KUM58971.1 - 1.3 7.9 9.1 2.5 7.0 9.1 1.4 1 0 0 1 1 1 0 PalH/RIM21 Ribosomal_L44 PF00935.19 KUM58972.1 - 3.6e-35 120.3 12.9 6.7e-35 119.4 12.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L44 Acetyltransf_1 PF00583.25 KUM58973.1 - 9.7e-06 25.8 0.0 1.4e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KUM58973.1 - 0.00018 21.9 0.0 0.00027 21.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KUM58973.1 - 0.0034 17.3 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.25 KUM58973.1 - 0.16 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.18 KUM58974.1 - 3e-13 49.4 0.6 5.8e-13 48.5 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM58974.1 - 1.1e-07 31.8 6.2 2e-07 31.0 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4449 PF14613.6 KUM58974.1 - 0.026 14.6 0.9 5.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) Wzy_C_2 PF11846.8 KUM58974.1 - 0.034 14.1 0.6 0.078 12.9 0.6 1.6 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal REC114-like PF15165.6 KUM58974.1 - 0.05 13.4 3.9 0.078 12.7 3.9 1.2 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Med3 PF11593.8 KUM58974.1 - 0.71 9.0 13.6 0.16 11.1 9.7 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Dickkopf_N PF04706.12 KUM58974.1 - 1.5 9.3 6.3 5.7 7.5 6.3 2.0 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region MFS_1 PF07690.16 KUM58975.1 - 1.3e-43 149.3 37.9 1.3e-43 149.3 37.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM58975.1 - 3e-11 42.8 4.3 3e-11 42.8 4.3 1.9 3 0 0 3 3 3 1 Sugar (and other) transporter DUF3824 PF12868.7 KUM58976.1 - 1.2e-12 48.7 30.4 1.2e-12 48.7 30.4 3.0 2 1 2 4 4 4 1 Domain of unknwon function (DUF3824) DUF4551 PF15087.6 KUM58976.1 - 3.3 6.4 4.0 3.8 6.2 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SPX PF03105.19 KUM58976.1 - 8.2 6.2 12.7 10 5.9 12.7 1.3 1 0 0 1 1 1 0 SPX domain Vac7 PF12751.7 KUM58977.1 - 2.7e-153 510.9 5.5 2.7e-153 510.9 5.5 2.2 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 PEP_hydrolase PF09370.10 KUM58978.1 - 1.8e-135 450.4 1.5 2e-135 450.2 1.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like S-methyl_trans PF02574.16 KUM58978.1 - 0.002 18.0 0.1 0.0037 17.1 0.1 1.3 1 1 0 1 1 1 1 Homocysteine S-methyltransferase NMO PF03060.15 KUM58978.1 - 0.002 17.6 4.1 0.0027 17.2 0.2 2.0 2 0 0 2 2 2 1 Nitronate monooxygenase Radical_SAM PF04055.21 KUM58978.1 - 0.095 13.1 0.0 1.3 9.4 0.1 2.2 1 1 1 2 2 2 0 Radical SAM superfamily CorA PF01544.18 KUM58980.1 - 1.5e-40 139.4 0.3 3.4e-40 138.2 0.3 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4611 PF15387.6 KUM58980.1 - 1 9.6 3.7 1 9.7 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) XPC-binding PF09280.11 KUM58981.1 - 7.5e-23 80.0 11.8 1.3e-22 79.3 11.8 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 KUM58981.1 - 3.8e-22 77.8 2.4 6e-13 48.4 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 KUM58981.1 - 5.9e-20 70.8 1.1 5.9e-20 70.8 1.1 1.9 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 KUM58981.1 - 4e-07 29.8 2.6 7.7e-07 28.9 2.6 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KUM58981.1 - 0.00052 20.3 0.4 0.00087 19.6 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KUM58981.1 - 0.00068 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KUM58981.1 - 0.0041 17.7 0.0 0.0091 16.5 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UBA_3 PF09288.10 KUM58981.1 - 0.042 13.7 0.0 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Glyco_transf_22 PF03901.17 KUM58982.1 - 9.9e-61 206.2 24.9 1.2e-60 205.9 24.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2975 PF11188.8 KUM58982.1 - 5.3 6.9 8.6 1.1 9.2 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Skp1 PF01466.19 KUM58983.1 - 2.6e-28 97.9 0.5 4.5e-28 97.1 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KUM58983.1 - 5.9e-24 84.0 0.2 1.5e-23 82.7 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain APH PF01636.23 KUM58984.1 - 0.0012 18.8 0.0 0.0012 18.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC_membrane PF00664.23 KUM58985.1 - 8.2e-96 320.8 34.1 6.3e-50 170.4 12.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KUM58985.1 - 1.7e-67 226.2 0.0 1.4e-32 113.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KUM58985.1 - 1.6e-14 53.9 0.0 1.5e-05 24.5 0.4 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KUM58985.1 - 6.3e-08 33.2 3.2 0.0075 16.7 0.2 3.7 2 2 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KUM58985.1 - 2.8e-07 31.0 0.2 4.8 7.6 0.0 4.8 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KUM58985.1 - 6.7e-07 29.7 0.5 0.049 13.9 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KUM58985.1 - 7.3e-07 28.8 0.6 0.0062 16.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KUM58985.1 - 4.2e-06 25.8 1.3 0.0089 14.9 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KUM58985.1 - 2.9e-05 24.0 0.0 0.47 10.3 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_30 PF13604.6 KUM58985.1 - 6.9e-05 22.6 3.9 0.53 10.0 0.0 4.1 5 0 0 5 5 5 2 AAA domain AAA_21 PF13304.6 KUM58985.1 - 0.00012 22.0 0.0 0.54 10.0 0.0 3.6 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KUM58985.1 - 0.00019 21.4 0.1 0.029 14.3 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 KUM58985.1 - 0.00087 18.9 0.8 0.54 9.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KUM58985.1 - 0.0015 18.5 0.4 3.6 7.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KUM58985.1 - 0.0016 18.0 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 KUM58985.1 - 0.0016 19.0 0.0 2.1 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KUM58985.1 - 0.0027 17.9 0.0 3 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KUM58985.1 - 0.0041 17.3 3.4 3.7 7.8 0.4 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KUM58985.1 - 0.0076 16.0 0.5 1.3 8.6 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain AAA_23 PF13476.6 KUM58985.1 - 0.013 16.0 0.6 7.9 6.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 KUM58985.1 - 0.015 15.0 0.1 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KUM58985.1 - 0.017 14.7 0.1 1.6 8.3 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 KUM58985.1 - 0.02 15.3 0.1 4 7.9 0.0 3.1 3 0 0 3 3 2 0 RNA helicase Tho1_MOS11_C PF18592.1 KUM58985.1 - 0.026 14.3 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Tho1/MOS11 C-terminal domain Zeta_toxin PF06414.12 KUM58985.1 - 0.029 13.6 0.0 9.9 5.4 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 KUM58985.1 - 0.033 14.4 0.6 1.3 9.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KUM58985.1 - 0.045 13.5 0.0 3.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase PRK PF00485.18 KUM58985.1 - 0.045 13.5 0.1 2.7 7.7 0.0 2.7 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 KUM58985.1 - 0.098 12.7 0.3 17 5.4 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Mg_chelatase PF01078.21 KUM58985.1 - 0.13 11.6 0.0 18 4.6 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 KUM58985.1 - 0.25 11.7 2.2 23 5.4 0.2 3.4 4 0 0 4 4 3 0 AAA domain Ytp1 PF10355.9 KUM58986.1 - 3.3e-71 239.7 21.2 1.6e-70 237.5 21.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KUM58986.1 - 6.6e-18 64.4 3.0 6.6e-18 64.4 3.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 KUM58986.1 - 0.00076 19.6 5.7 0.00076 19.6 5.7 3.6 4 0 0 4 4 4 1 Eukaryotic cytochrome b561 ExoD PF06055.12 KUM58986.1 - 0.041 13.3 0.2 0.041 13.3 0.2 2.1 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD ApoO PF09769.9 KUM58986.1 - 0.22 11.5 0.2 0.4 10.6 0.2 1.3 1 0 0 1 1 1 0 Apolipoprotein O S1FA PF04689.13 KUM58986.1 - 0.48 10.6 3.5 0.87 9.8 0.4 2.5 2 0 0 2 2 2 0 DNA binding protein S1FA DUF3180 PF11377.8 KUM58986.1 - 2.2 8.4 10.9 36 4.5 0.0 3.5 1 1 1 3 3 3 0 Protein of unknown function (DUF3180) ThiF PF00899.21 KUM58987.1 - 5.5e-29 101.2 0.0 7.5e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family Asp_protease PF09668.10 KUM58989.1 - 8.7e-61 203.2 0.1 1.3e-60 202.7 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KUM58989.1 - 8.6e-22 77.5 0.0 1.7e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KUM58989.1 - 1.5e-10 41.5 0.0 3.9e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 KUM58989.1 - 1.2e-08 34.5 0.1 2.1e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KUM58989.1 - 8.7e-06 25.5 0.1 2.3e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 KUM58989.1 - 0.00055 19.7 0.1 0.0013 18.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP_2 PF08284.11 KUM58989.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KUM58989.1 - 0.014 15.7 0.0 0.039 14.3 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease UBA_4 PF14555.6 KUM58989.1 - 0.026 14.3 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain NAD_binding_7 PF13241.6 KUM58989.1 - 0.16 12.4 0.1 0.66 10.4 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF2781 PF10914.8 KUM58990.1 - 1.7e-37 129.1 14.3 4.8e-37 127.6 14.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2781) API5 PF05918.11 KUM58992.1 - 7.6 5.2 12.1 0.17 10.7 1.2 2.3 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) RPN2_C PF18004.1 KUM58992.1 - 9.4 6.1 9.0 1.4 8.8 1.4 2.7 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nucleoporin_N PF08801.11 KUM58993.1 - 7.4e-89 298.5 0.3 1.2e-88 297.7 0.3 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KUM58993.1 - 9.5e-49 166.6 1.5 7.6e-46 157.1 0.4 2.1 2 0 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal Imm35 PF15567.6 KUM58993.1 - 0.077 13.2 0.0 0.54 10.5 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 35 TauD PF02668.16 KUM58994.1 - 8.7e-47 160.2 0.1 1e-46 159.9 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UPF0302 PF08864.10 KUM58994.1 - 0.028 14.5 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 UPF0302 domain Rot1 PF10681.9 KUM58995.1 - 1e-89 299.6 0.0 1.1e-89 299.4 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal YqeY PF09424.10 KUM58996.1 - 5e-19 68.8 3.4 6.2e-19 68.5 3.4 1.1 1 0 0 1 1 1 1 Yqey-like protein Aldedh PF00171.22 KUM58997.1 - 6e-167 555.8 0.3 6.9e-167 555.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Telomere_Sde2_2 PF13297.6 KUM58997.1 - 0.2 11.3 0.0 0.44 10.2 0.0 1.5 1 0 0 1 1 1 0 Telomere stability C-terminal NMT_C PF02799.15 KUM58998.1 - 1.8e-90 302.0 0.2 3.3e-90 301.2 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KUM58998.1 - 8.7e-75 249.9 0.2 6.2e-74 247.2 0.0 2.0 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KUM58998.1 - 3.1e-06 27.3 0.1 6.3e-05 23.1 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain NTP_transf_9 PF04248.12 KUM58998.1 - 0.023 14.6 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Acetyltransf_1 PF00583.25 KUM58998.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family RRN9 PF10680.9 KUM58999.1 - 8.1e-14 51.7 0.3 5e-13 49.1 0.3 2.5 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2_aberr PF17017.5 KUM58999.1 - 0.26 11.4 0.0 0.45 10.6 0.0 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger NPR3 PF03666.13 KUM58999.1 - 7.8 5.2 6.6 13 4.4 6.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pkinase PF00069.25 KUM59002.1 - 1e-18 67.7 0.0 1.3e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM59002.1 - 6.9e-11 41.9 0.0 8.7e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KUM59003.1 - 7.7e-21 74.6 0.0 9.3e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM59003.1 - 0.079 12.2 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Dimerisation PF08100.11 KUM59003.1 - 0.18 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain MARVEL PF01284.23 KUM59004.1 - 3.6e-13 49.8 9.0 4.7e-13 49.4 9.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain Syja_N PF02383.18 KUM59005.1 - 5e-91 305.3 0.1 6.3e-91 305.0 0.1 1.1 1 0 0 1 1 1 1 SacI homology domain ARGLU PF15346.6 KUM59005.1 - 0.13 12.1 3.4 0.21 11.4 3.4 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 GTP_EFTU PF00009.27 KUM59006.1 - 2.5e-57 193.6 0.4 4.2e-57 192.8 0.4 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KUM59006.1 - 7.8e-33 112.4 0.0 1.8e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KUM59006.1 - 7.8e-32 109.6 0.0 1.6e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KUM59006.1 - 4.4e-23 81.1 0.0 1e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KUM59006.1 - 6.7e-13 48.8 0.0 1.6e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KUM59006.1 - 7.5e-06 25.8 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Ribosomal_L36 PF00444.18 KUM59007.1 - 8.2e-21 73.9 8.3 1.5e-20 73.1 8.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L36 Ras PF00071.22 KUM59010.1 - 6.4e-59 198.2 0.2 7.4e-59 198.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM59010.1 - 1.3e-36 125.5 0.2 3.3e-36 124.1 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM59010.1 - 8.3e-15 54.7 0.0 1e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KUM59010.1 - 3.6e-07 29.8 0.0 4.4e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KUM59010.1 - 6.3e-07 29.1 0.0 8.9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KUM59010.1 - 1.3e-06 28.4 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KUM59010.1 - 2.5e-05 24.3 1.3 0.15 12.0 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KUM59010.1 - 0.015 15.7 0.2 0.031 14.6 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KUM59010.1 - 0.018 15.3 0.1 2.5 8.4 0.0 2.4 1 1 1 2 2 2 0 AAA domain Mitofilin PF09731.9 KUM59011.1 - 2.7e-152 508.8 34.8 1.9e-124 416.9 27.4 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Med30 PF11315.8 KUM59011.1 - 0.088 13.0 7.6 0.052 13.7 4.5 2.2 2 0 0 2 2 2 0 Mediator complex subunit 30 Sld5 PF05916.11 KUM59011.1 - 1.3 9.6 6.3 57 4.2 6.3 2.6 1 1 0 1 1 1 0 GINS complex protein Mur_ligase_M PF08245.12 KUM59012.1 - 7.2e-07 29.4 0.9 0.00079 19.5 0.9 3.4 1 1 0 1 1 1 1 Mur ligase middle domain DUF1471 PF07338.13 KUM59012.1 - 0.11 12.5 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Mur_ligase_C PF02875.21 KUM59012.1 - 0.16 12.2 0.0 0.51 10.6 0.0 1.9 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain PALP PF00291.25 KUM59013.1 - 9.5e-76 255.0 0.2 1.2e-75 254.6 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KUM59013.1 - 3e-45 151.9 0.0 8.4e-22 76.8 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.13 KUM59014.1 - 8.9e-13 48.2 0.4 1.3e-12 47.7 0.4 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region MAS20 PF02064.15 KUM59014.1 - 0.098 12.7 1.2 0.13 12.4 1.2 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor SPT16 PF08644.11 KUM59014.1 - 0.11 12.7 0.3 0.14 12.3 0.3 1.2 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) ATP-synt_E PF05680.12 KUM59014.1 - 0.28 11.6 6.1 0.086 13.2 2.3 1.9 1 1 1 2 2 2 0 ATP synthase E chain bZIP_1 PF00170.21 KUM59015.1 - 5.7e-07 29.5 9.4 9.3e-07 28.9 9.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KUM59015.1 - 2.4e-06 27.5 8.8 4.1e-06 26.8 8.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper MscS_TM PF12794.7 KUM59015.1 - 4.6 6.0 4.6 6.1 5.6 4.6 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Aminotran_3 PF00202.21 KUM59016.1 - 3.2e-126 421.3 0.0 3.6e-126 421.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Spt4 PF06093.13 KUM59017.1 - 2.8e-32 110.7 0.3 3.3e-32 110.4 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger TackOD1 PF18551.1 KUM59017.1 - 0.069 12.8 1.4 0.093 12.4 1.4 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Cut12 PF11500.8 KUM59020.1 - 6.9e-50 168.8 8.9 6.9e-50 168.8 8.9 4.1 3 1 0 4 4 4 1 Spindle pole body formation-associated protein Peptidase_S46 PF10459.9 KUM59020.1 - 2.6 6.6 28.2 4 6.0 28.2 1.2 1 0 0 1 1 1 0 Peptidase S46 Lebercilin PF15619.6 KUM59020.1 - 8.2 6.0 53.0 4.1 7.0 25.8 3.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Pdase_M17_N2 PF18295.1 KUM59020.1 - 8.6 6.6 8.0 0.77 10.0 1.6 2.5 2 1 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 Golgin_A5 PF09787.9 KUM59020.1 - 9.4 5.6 47.3 0.14 11.6 35.9 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 PPP5 PF08321.12 KUM59022.1 - 6.2e-32 109.8 0.6 1.1e-31 108.9 0.1 1.7 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 KUM59022.1 - 1.3e-31 110.7 0.1 1.9e-31 110.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KUM59022.1 - 6.8e-09 35.2 2.9 0.00045 19.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KUM59022.1 - 8e-09 35.0 3.4 0.07 13.3 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KUM59022.1 - 7e-07 28.8 3.1 0.012 15.3 0.3 3.4 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 KUM59022.1 - 1.6e-05 25.3 0.3 0.17 12.4 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KUM59022.1 - 0.0007 19.7 0.1 0.42 10.8 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KUM59022.1 - 0.0047 17.6 4.2 2.7 8.7 0.8 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KUM59022.1 - 0.014 15.8 0.8 1.9 9.0 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KUM59022.1 - 0.08 13.0 0.2 0.2 11.8 0.2 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 KUM59022.1 - 0.1 12.9 1.8 6.9 7.2 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KUM59022.1 - 0.35 11.8 2.8 21 6.2 0.2 4.1 3 1 2 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 KUM59022.1 - 1 9.5 3.5 4.8 7.3 0.3 2.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF89 PF01937.19 KUM59023.1 - 8.2e-137 455.9 0.0 9.4e-137 455.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Cytochrom_C550 PF14495.6 KUM59023.1 - 0.14 11.9 0.0 0.6 9.8 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c-550 domain Sugar_tr PF00083.24 KUM59024.1 - 4.1e-74 250.1 16.6 4.6e-74 249.9 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM59024.1 - 0.0028 16.6 25.1 0.0028 16.6 25.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DnaJ_C PF01556.18 KUM59025.1 - 4.5e-35 120.9 0.2 5.6e-35 120.6 0.2 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KUM59025.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain PIG-X PF08320.12 KUM59026.1 - 1.8e-69 233.9 0.0 3.8e-69 232.8 0.0 1.5 2 0 0 2 2 2 1 PIG-X / PBN1 Pkinase PF00069.25 KUM59027.1 - 6.1e-68 229.0 0.0 4.1e-36 124.7 0.0 4.4 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KUM59027.1 - 1.5e-35 122.7 0.0 2e-18 66.6 0.0 3.8 3 1 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 KUM59027.1 - 4.9e-17 62.3 0.0 1.5e-16 60.7 0.0 1.9 1 0 0 1 1 1 1 RWD domain APH PF01636.23 KUM59027.1 - 9.6e-05 22.4 4.2 0.00076 19.5 0.0 2.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KUM59027.1 - 0.00018 21.2 0.0 0.0066 16.1 0.0 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 DUF1682 PF07946.14 KUM59027.1 - 0.014 14.6 3.4 0.023 13.9 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Kinase-like PF14531.6 KUM59027.1 - 0.045 13.1 0.0 9.9 5.4 0.0 2.5 2 0 0 2 2 2 0 Kinase-like DUF3391 PF11871.8 KUM59027.1 - 2.1 8.9 6.1 1.9e+02 2.6 6.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF4267 PF14087.6 KUM59028.1 - 8.8e-30 103.1 2.6 1.1e-29 102.7 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF1304 PF06993.12 KUM59028.1 - 0.039 14.0 0.8 0.052 13.6 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1304) MMR_HSR1_Xtn PF16897.5 KUM59029.1 - 1.2e-29 102.5 5.6 2.9e-29 101.2 1.6 2.1 2 0 0 2 2 2 2 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KUM59029.1 - 1.3e-19 69.9 0.4 3.1e-19 68.8 0.1 1.7 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.23 KUM59030.1 - 1.3e-20 73.5 0.1 2.5e-20 72.7 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KUM59030.1 - 8.1e-13 48.2 0.0 1.1e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KUM59030.1 - 5.5e-05 23.3 1.5 0.046 13.8 0.0 2.4 2 1 1 3 3 3 2 Dynamin family MCM PF00493.23 KUM59030.1 - 0.0078 15.3 0.1 0.02 14.0 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MeaB PF03308.16 KUM59030.1 - 0.021 13.8 0.1 0.036 13.0 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 KUM59030.1 - 0.057 12.7 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.10 KUM59030.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Torus PF16131.5 KUM59031.1 - 1.4e-39 135.1 0.1 3.3e-39 134.0 0.1 1.6 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 KUM59031.1 - 2.9e-07 30.2 0.0 7.4e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KUM59031.1 - 0.00018 21.4 0.6 0.00034 20.6 0.6 1.5 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM_2 PF14605.6 KUM59031.1 - 0.02 14.9 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HGTP_anticodon2 PF12745.7 KUM59032.1 - 2.6e-84 282.8 4.6 3.7e-84 282.3 4.6 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.6 KUM59032.1 - 0.0005 19.4 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KUM59032.1 - 0.0038 17.3 0.1 0.008 16.3 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain HIF-1a_CTAD PF08778.10 KUM59032.1 - 0.034 13.8 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain Curto_V3 PF07436.11 KUM59032.1 - 0.07 13.5 0.1 2.9 8.4 0.0 2.5 1 1 1 2 2 2 0 Curtovirus V3 protein Zn_clus PF00172.18 KUM59033.1 - 2.1e-08 34.1 11.5 3.5e-08 33.4 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM59033.1 - 7.7e-06 25.1 0.1 1.9e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain GATase PF00117.28 KUM59036.1 - 8e-46 156.2 0.0 1.1e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KUM59036.1 - 1.5e-45 154.1 0.0 3.1e-45 153.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 KUM59036.1 - 2.3e-05 24.3 0.2 0.00081 19.2 0.1 2.4 1 1 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 KUM59036.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family AAA PF00004.29 KUM59037.1 - 5.7e-65 217.7 0.1 1.9e-41 141.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KUM59037.1 - 8.2e-20 70.3 0.4 3.8e-13 49.0 0.1 2.9 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KUM59037.1 - 3.6e-12 47.0 2.0 0.0039 17.6 0.1 4.8 3 2 2 5 5 4 2 AAA ATPase domain AAA_5 PF07728.14 KUM59037.1 - 4.8e-09 36.3 0.6 0.0055 16.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 KUM59037.1 - 1e-07 32.0 0.0 5.4e-06 26.4 0.0 2.7 2 2 0 2 2 2 1 Bacterial dnaA protein AAA_22 PF13401.6 KUM59037.1 - 2.4e-06 27.9 3.5 0.2 12.0 0.5 4.4 2 2 1 3 3 3 2 AAA domain RuvB_N PF05496.12 KUM59037.1 - 4.6e-06 26.5 0.0 0.012 15.4 0.0 3.5 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KUM59037.1 - 4.8e-06 26.6 0.0 0.05 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KUM59037.1 - 4.8e-06 26.2 0.1 0.092 12.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Rad17 PF03215.15 KUM59037.1 - 5.1e-06 26.5 0.4 0.00095 19.1 0.0 3.1 2 1 1 3 3 3 1 Rad17 P-loop domain IstB_IS21 PF01695.17 KUM59037.1 - 8.8e-06 25.6 0.0 0.0094 15.7 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 KUM59037.1 - 1e-05 25.2 0.2 0.16 11.5 0.0 3.9 3 1 1 4 4 4 1 AAA domain AAA_28 PF13521.6 KUM59037.1 - 3.4e-05 24.1 0.1 0.16 12.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 KUM59037.1 - 6.8e-05 22.1 0.0 0.1 11.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) TIP49 PF06068.13 KUM59037.1 - 8.5e-05 21.9 1.0 0.04 13.1 0.0 2.6 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_2 PF07724.14 KUM59037.1 - 0.00018 21.7 0.0 0.018 15.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KUM59037.1 - 0.00035 20.9 0.0 1.7 9.1 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.6 KUM59037.1 - 0.00071 19.4 0.0 0.037 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KUM59037.1 - 0.0021 18.0 1.0 0.17 11.8 0.2 3.2 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KUM59037.1 - 0.0022 18.2 0.0 4.1 7.6 0.2 2.8 2 1 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KUM59037.1 - 0.0061 17.1 0.2 0.87 10.1 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_11 PF13086.6 KUM59037.1 - 0.0062 16.4 0.0 1.8 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KUM59037.1 - 0.0069 16.9 0.1 0.4 11.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KUM59037.1 - 0.0082 15.9 0.0 0.65 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KUM59037.1 - 0.012 15.6 2.7 1.2 9.1 0.4 3.4 3 0 0 3 3 3 0 NACHT domain Mg_chelatase PF01078.21 KUM59037.1 - 0.02 14.3 0.1 3.6 6.9 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KUM59037.1 - 0.026 14.5 0.0 8.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 KUM59037.1 - 0.031 14.8 0.0 0.084 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain CDC48_N PF02359.18 KUM59037.1 - 0.032 14.4 0.0 0.085 13.0 0.0 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain SRPRB PF09439.10 KUM59037.1 - 0.047 13.1 0.1 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KUM59037.1 - 0.081 12.3 0.0 9.6 5.6 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein Vps4_C PF09336.10 KUM59037.1 - 0.088 12.8 0.0 1.9 8.6 0.0 3.0 3 0 0 3 3 2 0 Vps4 C terminal oligomerisation domain AAA_19 PF13245.6 KUM59037.1 - 0.09 13.1 0.1 18 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 KUM59038.1 - 2.7e-65 218.9 0.0 3.2e-65 218.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM59038.1 - 4.8e-34 117.2 0.0 7.2e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM59038.1 - 6.5e-14 51.8 0.0 8.4e-14 51.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KUM59038.1 - 4.2e-06 26.4 0.0 8.9e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KUM59038.1 - 0.00013 21.4 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KUM59038.1 - 0.00076 19.4 0.2 0.78 9.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KUM59038.1 - 0.004 17.2 0.0 0.008 16.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KUM59038.1 - 0.022 14.3 0.0 0.11 12.0 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 KUM59038.1 - 0.039 13.4 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KUM59038.1 - 0.16 12.2 0.0 0.48 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain PI3_PI4_kinase PF00454.27 KUM59039.1 - 1.1e-51 176.1 0.0 2.1e-51 175.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KUM59039.1 - 1.2e-39 136.5 2.0 4e-39 134.8 2.0 2.0 1 0 0 1 1 1 1 FAT domain UME PF08064.13 KUM59039.1 - 4e-37 126.2 0.5 1.6e-36 124.3 0.5 2.2 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 KUM59039.1 - 8.7e-13 47.9 0.0 2e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 FATC domain TPR_14 PF13428.6 KUM59039.1 - 0.00065 20.3 3.2 8.5 7.5 0.4 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KUM59039.1 - 0.0017 18.8 0.5 0.52 10.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KUM59039.1 - 0.003 17.5 0.2 16 5.8 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KUM59039.1 - 0.0045 16.7 1.7 0.13 12.0 0.4 2.6 2 0 0 2 2 2 1 TPR repeat BTAD PF03704.17 KUM59039.1 - 0.1 13.0 1.8 4.3 7.8 0.0 2.9 2 0 0 2 2 2 0 Bacterial transcriptional activator domain DUF3385 PF11865.8 KUM59039.1 - 0.15 11.9 0.0 1.4 8.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) RRM_1 PF00076.22 KUM59040.1 - 2.2e-13 49.8 0.0 3.5e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KUM59040.1 - 0.0029 17.6 0.2 0.0064 16.5 0.0 1.7 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.6 KUM59040.1 - 0.097 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NADH-u_ox-rdase PF10785.9 KUM59041.1 - 9.2e-30 103.2 0.1 1.5e-29 102.5 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KUM59041.1 - 4.4e-26 90.7 0.1 5.9e-26 90.3 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit dCMP_cyt_deam_1 PF00383.23 KUM59042.1 - 9.3e-26 89.7 0.0 1.1e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KUM59042.1 - 3.7e-19 68.9 0.0 4.6e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 KUM59042.1 - 0.0046 17.1 0.0 0.0059 16.7 0.0 1.3 1 0 0 1 1 1 1 APOBEC3 SNAD4 PF18750.1 KUM59042.1 - 0.0053 16.9 0.0 0.0081 16.3 0.0 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 XOO_2897-deam PF14440.6 KUM59042.1 - 0.0084 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.11 KUM59042.1 - 0.042 13.7 0.0 0.051 13.5 0.0 1.1 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Bd3614-deam PF14439.6 KUM59042.1 - 0.043 13.9 1.0 0.13 12.3 0.2 1.9 1 1 1 2 2 2 0 Bd3614-like deaminase NAD1 PF18778.1 KUM59042.1 - 0.059 13.5 0.0 0.079 13.0 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 KUM59042.1 - 0.086 12.9 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 APOBEC2 APOBEC4_like PF18774.1 KUM59042.1 - 0.097 12.6 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase RCC1 PF00415.18 KUM59043.1 - 6.8e-56 186.7 11.2 6e-10 39.6 0.2 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KUM59043.1 - 5.9e-31 105.6 37.1 2.8e-07 30.2 1.7 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Swi3 PF07962.12 KUM59044.1 - 8.7e-35 118.6 0.5 1.3e-34 118.0 0.5 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Y_phosphatase PF00102.27 KUM59045.1 - 3.7e-60 203.4 0.0 4.4e-59 199.9 0.0 2.2 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 KUM59045.1 - 4.6e-07 30.3 0.0 1.4e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 KUM59045.1 - 0.0045 16.8 0.1 0.0097 15.7 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KUM59045.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family COX16 PF14138.6 KUM59046.1 - 3.6e-30 104.3 0.1 4.7e-30 103.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Arc_PepC_II PF06847.11 KUM59046.1 - 0.022 15.3 0.0 0.085 13.4 0.0 1.8 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Nic96 PF04097.14 KUM59047.1 - 2.9e-218 726.3 0.0 3.8e-218 725.9 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 KUM59047.1 - 0.045 14.6 41.1 0.12 13.2 31.5 2.5 2 0 0 2 2 2 0 Nucleoporin FG repeat region RibD_C PF01872.17 KUM59048.1 - 1.1e-29 103.7 0.0 1.6e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain Na_Ca_ex PF01699.24 KUM59049.1 - 1.6e-23 83.3 24.3 9.9e-16 58.0 11.0 4.0 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 KUM59049.1 - 3.1e-14 53.4 10.0 3.1e-14 53.4 10.0 4.0 3 0 0 3 3 3 1 Inner membrane component domain FGGY_C PF02782.16 KUM59050.1 - 3.4e-51 173.8 0.2 4.9e-51 173.3 0.2 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KUM59050.1 - 7.8e-23 81.3 0.0 3.3e-20 72.7 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KUM59050.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DEDD_Tnp_IS110 PF01548.17 KUM59050.1 - 0.18 11.6 1.3 1 9.3 0.2 2.2 2 0 0 2 2 2 0 Transposase F-box-like_2 PF13013.6 KUM59052.1 - 0.0028 17.6 0.0 0.0059 16.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.33 KUM59052.1 - 0.031 14.2 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KUM59052.1 - 0.73 9.8 3.6 0.27 11.1 0.1 2.2 3 0 0 3 3 3 0 F-box-like Alginate_lyase PF05426.12 KUM59053.1 - 1.1e-20 74.3 3.0 2e-20 73.5 3.0 1.3 1 1 0 1 1 1 1 Alginate lyase Glyco_hydro_88 PF07470.13 KUM59054.1 - 9.5e-13 47.9 0.4 1.3e-12 47.4 0.4 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_28 PF00295.17 KUM59055.1 - 1.7e-11 43.8 2.9 3e-11 43.0 2.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KUM59055.1 - 6.2e-05 22.9 10.0 0.026 14.4 5.5 2.6 1 1 1 2 2 2 2 Right handed beta helix region MFS_1 PF07690.16 KUM59056.1 - 1.1e-35 123.3 23.1 1.1e-35 123.3 23.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1003 PF06210.11 KUM59056.1 - 0.033 14.3 2.0 0.035 14.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) TMEM154 PF15102.6 KUM59056.1 - 0.14 12.1 2.6 2.6 7.9 0.0 2.8 3 0 0 3 3 3 0 TMEM154 protein family TMEM138 PF14935.6 KUM59056.1 - 3.4 8.3 10.2 1.2 9.8 0.2 3.3 2 1 1 3 3 3 0 Transmembrane protein 138 Alginate_lyase PF05426.12 KUM59057.1 - 2.2e-15 56.9 2.9 5.1e-15 55.7 2.9 1.5 1 1 0 1 1 1 1 Alginate lyase UDPGT PF00201.18 KUM59058.1 - 1.2e-18 67.2 0.0 7.3e-18 64.6 0.0 2.0 2 1 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 KUM59058.1 - 0.032 14.3 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 KUM59058.1 - 0.058 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Fungal_trans PF04082.18 KUM59059.1 - 3.7e-20 72.1 0.2 6.5e-20 71.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM59059.1 - 3.1e-09 36.8 11.8 6.2e-09 35.8 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Synaptobrevin PF00957.21 KUM59060.1 - 0.0012 18.6 0.6 0.0018 18.0 0.6 1.2 1 0 0 1 1 1 1 Synaptobrevin T2SSF PF00482.23 KUM59060.1 - 0.0056 16.6 0.0 0.0078 16.2 0.0 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F PID_2 PF14719.6 KUM59060.1 - 0.17 11.7 0.1 0.25 11.2 0.1 1.2 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) FH2 PF02181.23 KUM59061.1 - 2.8e-91 306.4 1.4 2.8e-91 306.4 1.4 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KUM59061.1 - 7.1e-68 227.9 0.0 7.1e-68 227.9 0.0 2.2 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KUM59061.1 - 5e-52 176.4 0.5 5.2e-51 173.0 0.1 2.6 1 1 1 2 2 2 1 Diaphanous FH3 Domain zf-C2H2_2 PF12756.7 KUM59063.1 - 0.017 15.5 0.2 0.033 14.5 0.2 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KUM59063.1 - 0.073 13.5 0.1 1.3 9.6 0.0 2.1 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_7 PF15269.6 KUM59063.1 - 0.1 12.7 5.2 1.7 8.7 2.2 2.3 2 0 0 2 2 2 0 Zinc-finger zf-C2H2_4 PF13894.6 KUM59063.1 - 0.19 12.7 7.7 0.38 11.7 2.5 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger HscB_4_cys PF18256.1 KUM59063.1 - 0.21 11.4 0.2 0.21 11.4 0.2 2.4 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif DZR PF12773.7 KUM59063.1 - 0.37 10.9 3.4 0.13 12.3 0.5 1.7 2 0 0 2 2 2 0 Double zinc ribbon TrmE_N PF10396.9 KUM59064.1 - 1.6e-36 125.1 0.0 3e-36 124.2 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 KUM59064.1 - 9.2e-27 94.6 0.0 2.4e-26 93.2 0.0 1.7 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 KUM59064.1 - 7.9e-18 64.6 0.0 1.2e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KUM59064.1 - 2.1e-05 24.1 0.1 7.1e-05 22.4 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KUM59064.1 - 0.0001 21.9 0.0 0.0081 15.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KUM59064.1 - 0.00017 21.7 0.0 0.00027 21.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin family AAA_24 PF13479.6 KUM59064.1 - 0.004 16.9 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 KUM59064.1 - 0.11 12.7 0.1 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KUM59064.1 - 0.17 11.7 0.1 0.71 9.7 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase tRNA-synt_1 PF00133.22 KUM59065.1 - 8.6e-53 179.5 0.0 1.2e-34 119.6 0.1 6.2 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KUM59065.1 - 1.6e-39 135.4 0.0 2.4e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KUM59065.1 - 1.4e-27 96.5 0.1 1.9e-20 73.0 0.0 4.2 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KUM59065.1 - 9.9e-10 38.6 0.0 2.6e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.19 KUM59065.1 - 0.0034 16.4 0.0 0.0096 14.9 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (R) adh_short PF00106.25 KUM59066.1 - 2.2e-32 112.1 0.0 2.9e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM59066.1 - 7e-21 74.9 0.0 8.7e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM59066.1 - 2.9e-10 40.3 0.0 4.4e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM59066.1 - 2.4e-06 27.2 0.0 4.5e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KUM59066.1 - 0.00062 18.9 0.0 0.00081 18.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KUM59066.1 - 0.0024 17.0 0.0 0.0031 16.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KUM59066.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 2 0 0 2 2 2 0 NAD(P)H-binding DapB_N PF01113.20 KUM59066.1 - 0.021 14.9 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 KUM59066.1 - 0.03 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.19 KUM59066.1 - 0.091 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KUM59066.1 - 0.12 11.5 0.0 14 4.8 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein 2-Hacid_dh_C PF02826.19 KUM59067.1 - 4.3e-52 176.1 0.0 7.6e-52 175.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KUM59067.1 - 1.7e-15 56.8 0.0 2.4e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KUM59067.1 - 0.0012 19.1 0.0 0.0028 17.8 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Suc_Fer-like PF06999.12 KUM59068.1 - 1e-58 198.5 0.0 1.2e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Sec1 PF00995.23 KUM59069.1 - 9.8e-122 408.1 0.0 1.1e-121 407.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_tran_WecB PF03808.13 KUM59069.1 - 0.095 12.6 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family MBOAT PF03062.19 KUM59070.1 - 4.7e-53 180.8 9.9 1.6e-52 179.0 9.9 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KUM59071.1 - 2.9e-25 88.3 0.4 7.8e-25 87.0 0.2 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family FA_desaturase PF00487.24 KUM59072.1 - 4.2e-23 82.5 18.7 9.5e-23 81.3 18.7 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KUM59072.1 - 1.8e-05 24.9 0.0 4.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Pilt PF15453.6 KUM59072.1 - 3.8 6.8 8.2 5.1 6.4 8.2 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions p450 PF00067.22 KUM59073.1 - 3.2e-26 92.1 0.0 4.4e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Velvet PF11754.8 KUM59074.1 - 2.9e-36 125.7 0.0 9.4e-20 71.6 0.0 2.1 1 1 1 2 2 2 2 Velvet factor DUF1803 PF08820.10 KUM59074.1 - 0.098 12.7 0.0 0.33 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1803) Rad51 PF08423.11 KUM59075.1 - 4.5e-38 131.0 0.0 1.9e-34 119.1 0.0 2.3 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 KUM59075.1 - 3.9e-06 26.6 0.0 7.3e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KUM59075.1 - 0.04 13.3 0.2 0.1 11.9 0.2 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ATPase PF06745.13 KUM59075.1 - 0.081 12.3 0.2 7 5.9 0.0 2.4 2 0 0 2 2 2 0 KaiC ER-remodelling PF14755.6 KUM59075.1 - 6 7.1 11.3 0.065 13.5 2.2 2.3 3 0 0 3 3 3 0 Intracellular membrane remodeller TRAPPC10 PF12584.8 KUM59076.1 - 2.5e-45 154.0 0.0 5.2e-45 152.9 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 KUM59076.1 - 0.021 14.4 0.4 0.045 13.3 0.4 1.5 1 0 0 1 1 1 0 Foie gras liver health family 1 UBN_AB PF14075.6 KUM59076.1 - 0.066 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Glyco_hydro_61 PF03443.14 KUM59077.1 - 2.5e-67 226.8 3.1 1.1e-66 224.7 0.2 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 61 TIG PF01833.24 KUM59078.1 - 2.4e-10 40.3 0.7 9e-10 38.5 0.4 2.1 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.6 KUM59078.1 - 6.2e-09 35.9 4.0 2.2e-05 24.6 1.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KUM59078.1 - 9.2e-07 29.1 2.8 0.018 15.5 0.8 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KUM59078.1 - 2.7e-06 27.9 0.0 5.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM59078.1 - 4.7e-05 23.8 0.6 0.00028 21.4 0.4 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM59078.1 - 0.00047 20.4 0.4 2.2 9.1 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeat Aminotran_3 PF00202.21 KUM59079.1 - 2.3e-53 181.3 0.0 7e-53 179.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-III p450 PF00067.22 KUM59080.1 - 8.5e-20 70.9 0.1 1e-19 70.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 SUI1 PF01253.22 KUM59081.1 - 3.1e-22 78.9 0.8 9.4e-22 77.3 0.8 1.9 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 KUM59081.1 - 1.3e-09 38.6 0.4 2.7e-08 34.4 0.4 2.8 1 1 0 1 1 1 1 Pre-PUA-like domain Kin17_mid PF10357.9 KUM59081.1 - 0.0077 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein CENP-O PF09496.10 KUM59081.1 - 0.054 13.5 0.0 11 5.9 0.0 3.1 3 0 0 3 3 3 0 Cenp-O kinetochore centromere component zf-C2H2 PF00096.26 KUM59083.1 - 0.011 16.2 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KUM59083.1 - 0.019 14.7 0.1 0.05 13.4 0.0 1.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KUM59083.1 - 0.18 12.8 0.0 0.35 11.8 0.0 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Vps39_1 PF10366.9 KUM59084.1 - 8.4e-31 106.5 0.1 3.5e-28 98.0 0.0 3.3 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KUM59084.1 - 5.3e-23 81.6 0.0 1.4e-22 80.2 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KUM59084.1 - 2.2e-17 63.6 0.0 4.5e-17 62.5 0.0 1.4 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 KUM59084.1 - 6.4e-11 42.3 4.4 2.3e-09 37.3 3.5 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_1 PF00515.28 KUM59084.1 - 0.00013 21.7 0.8 2.8 7.9 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF1471 PF07338.13 KUM59084.1 - 0.016 15.2 0.0 0.052 13.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) TPR_7 PF13176.6 KUM59084.1 - 0.046 13.8 1.1 51 4.2 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM59084.1 - 0.088 13.0 1.0 12 6.2 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KUM59084.1 - 0.098 12.8 1.9 26 5.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 KUM59084.1 - 0.16 12.2 0.2 29 5.2 0.0 4.4 5 0 0 5 5 5 0 PPR repeat TPR_12 PF13424.6 KUM59084.1 - 0.46 10.8 7.0 51 4.2 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KUM59084.1 - 0.49 11.2 2.3 3.1e+02 2.4 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KUM59084.1 - 0.99 9.8 3.0 5.2 7.5 0.3 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Gon7 PF08738.10 KUM59085.1 - 3.7e-12 46.3 4.2 9.2e-12 45.0 1.1 2.0 1 1 1 2 2 2 1 Gon7 family DUF354 PF04007.12 KUM59085.1 - 0.081 12.0 0.0 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF354) RRM_1 PF00076.22 KUM59086.1 - 1e-16 60.5 0.0 8.4e-13 48.0 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KUM59086.1 - 0.11 12.6 0.0 0.39 10.8 0.0 1.9 1 0 0 1 1 1 0 Limkain b1 RRM_5 PF13893.6 KUM59086.1 - 0.13 11.9 0.0 0.45 10.1 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 6PF2K PF01591.18 KUM59087.1 - 5.2e-77 258.1 0.0 7.1e-77 257.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KUM59087.1 - 4.2e-40 137.5 0.0 7.2e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KUM59087.1 - 2.9e-05 24.2 0.0 6.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KUM59087.1 - 0.00019 21.0 0.0 0.0003 20.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA PF00004.29 KUM59088.1 - 4e-16 59.6 0.0 1.4e-15 57.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GEMIN8 PF15348.6 KUM59088.1 - 7.1e-07 29.8 4.5 5.3e-05 23.6 0.0 2.7 1 1 1 2 2 1 1 Gemini of Cajal bodies-associated protein 8 AAA_22 PF13401.6 KUM59088.1 - 0.00057 20.2 0.6 0.0075 16.5 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KUM59088.1 - 0.00084 19.4 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KUM59088.1 - 0.0069 16.8 0.1 0.0069 16.8 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 KUM59088.1 - 0.0079 16.5 0.2 0.03 14.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KUM59088.1 - 0.014 15.2 2.5 0.022 14.5 0.2 2.5 3 1 0 3 3 3 0 AAA domain AAA_11 PF13086.6 KUM59088.1 - 0.023 14.5 0.0 0.023 14.5 0.0 3.6 2 1 1 3 3 1 0 AAA domain AAA_33 PF13671.6 KUM59088.1 - 0.2 11.8 0.0 0.2 11.8 0.0 2.7 3 1 0 3 3 3 0 AAA domain Peptidase_S64 PF08192.11 KUM59088.1 - 0.52 8.7 21.0 0.78 8.1 21.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 AF-4 PF05110.13 KUM59088.1 - 0.8 7.7 53.8 2 6.4 25.8 2.5 1 1 1 2 2 2 0 AF-4 proto-oncoprotein Ldh_1_C PF02866.18 KUM59089.1 - 3.4e-47 160.5 0.0 6.4e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KUM59089.1 - 1.7e-42 144.8 0.0 2.9e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KUM59089.1 - 0.00025 20.2 0.0 0.00035 19.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KUM59089.1 - 0.021 15.3 0.2 0.16 12.4 0.0 2.4 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KUM59089.1 - 0.033 13.5 0.0 0.39 10.0 0.0 2.6 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HbrB PF08539.11 KUM59090.1 - 2.7e-47 160.9 0.0 4.9e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 HbrB-like Sec7 PF01369.20 KUM59092.1 - 1.9e-69 233.0 0.9 7.3e-69 231.1 0.9 2.1 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KUM59092.1 - 5.5e-41 140.1 2.7 5.5e-41 140.1 2.7 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KUM59092.1 - 9.6e-34 115.1 7.4 1.2e-32 111.6 0.0 5.6 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 KUM59092.1 - 9.3e-17 61.2 5.7 7.4e-16 58.3 0.4 3.3 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 LTXXQ PF07813.12 KUM59092.1 - 0.52 11.1 4.3 2.9 8.6 0.3 3.8 3 0 0 3 3 3 0 LTXXQ motif family protein 2-oxoacid_dh PF00198.23 KUM59093.1 - 5.3e-75 251.9 0.2 6.9e-75 251.5 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KUM59093.1 - 7e-17 61.0 0.3 2e-16 59.6 0.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KUM59093.1 - 1e-11 45.0 1.5 3e-11 43.5 0.9 2.1 2 0 0 2 2 2 1 e3 binding domain DUF3614 PF12267.8 KUM59093.1 - 9.9 6.6 7.3 0.5 10.8 0.1 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3614) Pribosyltran_N PF13793.6 KUM59094.1 - 3.8e-44 149.3 0.1 5.3e-43 145.6 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KUM59094.1 - 4e-31 108.5 0.1 3.5e-26 92.4 0.1 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KUM59094.1 - 2.5e-07 30.4 0.1 7.5e-05 22.3 0.1 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain PLDc_2 PF13091.6 KUM59095.1 - 1.2e-16 60.8 0.1 8.7e-06 25.7 0.1 3.8 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KUM59095.1 - 3.1e-11 43.0 5.0 3.1e-06 27.1 0.4 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF5353 PF17304.2 KUM59096.1 - 1.1e-33 114.8 2.2 1.5e-33 114.4 2.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5353) Sin3a_C PF16879.5 KUM59096.1 - 0.086 12.5 0.4 0.11 12.2 0.4 1.1 1 0 0 1 1 1 0 C-terminal domain of Sin3a protein V-SNARE_C PF12352.8 KUM59097.1 - 7.3e-14 51.8 0.5 1.8e-13 50.5 0.3 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KUM59097.1 - 0.00051 19.9 0.0 0.0014 18.5 0.0 1.7 2 0 0 2 2 2 1 Sec20 She9_MDM33 PF05546.11 KUM59097.1 - 0.039 13.8 0.1 0.07 12.9 0.1 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family BAR_2 PF10455.9 KUM59097.1 - 0.046 12.8 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Snapin_Pallidin PF14712.6 KUM59097.1 - 0.06 13.8 0.3 0.57 10.6 0.1 2.1 2 0 0 2 2 2 0 Snapin/Pallidin SprA-related PF12118.8 KUM59097.1 - 0.06 12.5 0.2 0.076 12.1 0.2 1.1 1 0 0 1 1 1 0 SprA-related family IFT20 PF14931.6 KUM59097.1 - 0.086 13.0 0.2 0.32 11.2 0.2 1.8 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Uso1_p115_C PF04871.13 KUM59097.1 - 0.094 13.1 0.4 0.18 12.1 0.4 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Sigma70_r4 PF04545.16 KUM59097.1 - 0.1 12.2 0.2 0.23 11.0 0.2 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 NAD_binding_7 PF13241.6 KUM59098.1 - 8.9e-33 112.8 0.1 1.5e-32 112.1 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KUM59098.1 - 3.9e-32 109.7 0.1 6.2e-32 109.0 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KUM59098.1 - 3.2e-14 52.1 0.0 3.2e-14 52.1 0.0 1.7 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 KUM59098.1 - 0.0036 16.6 0.0 0.0051 16.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KUM59098.1 - 0.0053 16.8 0.0 0.0086 16.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase LSDAT_prok PF18171.1 KUM59098.1 - 0.029 13.6 0.1 0.047 12.9 0.1 1.3 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote TrkA_N PF02254.18 KUM59098.1 - 0.048 13.9 0.3 0.11 12.7 0.3 1.6 1 1 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KUM59098.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 KUM59098.1 - 0.085 12.2 1.7 0.2 11.0 0.2 1.9 1 1 1 2 2 2 0 ThiF family FGE-sulfatase PF03781.16 KUM59099.1 - 2.9e-10 40.2 0.9 5e-10 39.4 0.9 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KUM59099.1 - 2.7e-05 24.7 1.0 9.6e-05 22.9 0.7 2.1 1 1 1 2 2 2 1 DinB superfamily ABC_membrane PF00664.23 KUM59100.1 - 5.2e-95 318.2 30.4 2.2e-50 171.8 15.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KUM59100.1 - 1.4e-66 223.2 0.1 3.7e-32 111.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KUM59100.1 - 3e-13 49.7 9.2 1.1e-05 25.0 0.5 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KUM59100.1 - 4.7e-07 29.5 0.8 0.0039 16.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KUM59100.1 - 2.6e-06 26.5 4.1 0.0067 15.3 0.3 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 KUM59100.1 - 2.1e-05 24.8 2.3 0.039 14.2 0.1 3.7 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KUM59100.1 - 2.6e-05 24.2 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KUM59100.1 - 0.00014 21.7 0.0 0.5 10.0 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KUM59100.1 - 0.00016 21.6 0.3 2.1 8.1 0.0 3.6 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KUM59100.1 - 0.00045 20.6 3.5 0.058 13.8 0.1 2.9 2 2 0 2 2 2 1 AAA ATPase domain G-alpha PF00503.20 KUM59100.1 - 0.0041 16.3 0.0 0.79 8.8 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit DUF87 PF01935.17 KUM59100.1 - 0.0044 17.2 0.4 2.1 8.4 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 KUM59100.1 - 0.0069 16.1 3.9 0.84 9.3 0.0 3.8 3 1 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 KUM59100.1 - 0.0077 15.5 0.6 0.39 10.0 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_23 PF13476.6 KUM59100.1 - 0.013 16.0 0.2 6.6 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KUM59100.1 - 0.026 14.3 1.2 0.34 10.7 0.1 3.0 2 2 0 2 2 2 0 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 KUM59100.1 - 0.057 13.5 0.1 18 5.5 0.1 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.7 KUM59100.1 - 0.085 11.8 0.1 5.9 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.6 KUM59100.1 - 0.086 13.1 10.5 2.5 8.4 0.2 4.2 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Usp PF00582.26 KUM59100.1 - 0.091 13.3 1.4 29 5.1 0.1 3.2 2 1 1 3 3 3 0 Universal stress protein family AAA_5 PF07728.14 KUM59100.1 - 0.2 11.7 0.5 9.3 6.2 0.0 3.4 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KUM59100.1 - 5.5 6.5 8.7 4 7.0 0.0 3.9 4 1 1 5 5 5 0 AAA domain AMP-binding PF00501.28 KUM59101.1 - 3.1e-74 250.1 0.1 4.4e-74 249.6 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KUM59101.1 - 1.1e-70 238.6 1.2 1.7e-70 238.0 1.2 1.2 1 0 0 1 1 1 1 Condensation domain Thioesterase PF00975.20 KUM59101.1 - 6.2e-16 59.2 0.2 2.1e-15 57.5 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 KUM59101.1 - 6.7e-10 39.2 0.0 1.3e-08 35.0 0.0 2.7 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 KUM59101.1 - 9.2e-09 36.2 0.2 7e-08 33.3 0.1 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM59101.1 - 9.2e-06 25.5 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_11 PF08241.12 KUM59101.1 - 8.3e-05 23.2 0.0 0.0041 17.7 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM59101.1 - 0.0014 18.4 0.0 0.0061 16.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM59101.1 - 0.0017 19.0 0.0 0.0087 16.7 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain AMP-binding_C PF13193.6 KUM59101.1 - 0.0074 17.2 0.2 0.42 11.6 0.0 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Abhydrolase_3 PF07859.13 KUM59101.1 - 0.0098 15.8 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_31 PF13847.6 KUM59101.1 - 0.018 14.9 0.0 0.12 12.2 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain DSHCT PF08148.12 KUM59102.1 - 1.1e-52 178.0 0.8 2.9e-52 176.6 0.8 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KUM59102.1 - 1.2e-40 138.4 0.1 2.6e-40 137.4 0.1 1.6 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KUM59102.1 - 7.5e-25 88.4 0.2 1.4e-24 87.4 0.2 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KUM59102.1 - 1.4e-17 64.0 0.0 3.2e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM59102.1 - 7.2e-06 26.3 0.0 1.8e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM59102.1 - 5.7e-05 23.2 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ntox28 PF15605.6 KUM59102.1 - 0.037 14.3 0.2 0.67 10.2 0.0 2.7 2 0 0 2 2 2 0 Bacterial toxin 28 IBN_N PF03810.19 KUM59103.1 - 3.1e-16 59.0 0.1 1e-12 47.8 0.0 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 KUM59103.1 - 7.2e-10 38.2 0.0 1.4e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 KUM59103.1 - 0.0012 17.4 1.4 0.3 9.5 0.1 2.8 3 0 0 3 3 3 2 CAS/CSE protein, C-terminus Xpo1 PF08389.12 KUM59103.1 - 0.0013 18.8 0.7 0.037 14.1 0.0 3.2 3 0 0 3 3 3 1 Exportin 1-like protein RTP1_C1 PF10363.9 KUM59103.1 - 0.0038 17.4 0.6 0.23 11.6 0.1 3.1 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 KUM59103.1 - 0.048 13.4 0.0 2.8 7.7 0.0 3.6 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 KUM59103.1 - 0.052 13.9 0.3 6.5 7.2 0.0 3.5 3 0 0 3 3 3 0 HEAT repeats SDA1 PF05285.12 KUM59103.1 - 1.7 8.0 8.6 2.9 7.2 8.6 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KUM59103.1 - 3 5.8 16.4 8.1 4.4 16.4 1.7 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 KUM59103.1 - 3.3 7.0 6.6 5.6 6.2 6.6 1.3 1 0 0 1 1 1 0 BUD22 HEAT_EZ PF13513.6 KUM59103.1 - 6 7.5 7.0 26 5.5 0.7 4.7 4 3 0 4 4 4 0 HEAT-like repeat RRM_1 PF00076.22 KUM59104.1 - 1.9e-08 34.0 0.0 5.3e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KUM59104.1 - 4.2e-08 33.1 0.0 7.8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KUM59104.1 - 0.011 15.5 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF2046 PF09755.9 KUM59105.1 - 0.0016 17.8 0.3 0.14 11.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) CENP-F_N PF10481.9 KUM59105.1 - 0.017 14.8 0.9 0.017 14.8 0.9 2.2 1 1 1 2 2 2 0 Cenp-F N-terminal domain bZIP_2 PF07716.15 KUM59105.1 - 0.046 13.8 7.2 0.11 12.7 0.8 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DegS PF05384.11 KUM59105.1 - 0.048 13.2 0.7 0.048 13.2 0.7 2.1 2 0 0 2 2 2 0 Sensor protein DegS SlyX PF04102.12 KUM59105.1 - 0.055 14.1 5.1 3.7 8.3 1.3 2.6 2 0 0 2 2 2 0 SlyX FlaC_arch PF05377.11 KUM59105.1 - 0.19 12.1 1.7 0.43 11.0 0.1 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Pox_A_type_inc PF04508.12 KUM59105.1 - 0.24 11.3 4.4 0.77 9.7 4.4 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat HIP1_clath_bdg PF16515.5 KUM59105.1 - 0.45 11.1 7.4 6.5 7.4 1.5 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Rho_Binding PF08912.11 KUM59105.1 - 0.79 10.6 4.3 0.75 10.7 1.1 2.1 2 0 0 2 2 2 0 Rho Binding Csm1_N PF18504.1 KUM59105.1 - 1 9.8 5.4 2.5 8.5 2.1 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF1640 PF07798.11 KUM59105.1 - 1.1 9.3 5.9 0.9 9.6 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) CCDC14 PF15254.6 KUM59105.1 - 5.9 5.4 15.0 0.043 12.5 2.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 14 DivIC PF04977.15 KUM59105.1 - 6.7 6.6 5.8 6.2 6.7 1.7 2.1 2 0 0 2 2 2 0 Septum formation initiator ATG16 PF08614.11 KUM59105.1 - 7.5 6.7 17.8 1.9e+03 -1.1 17.8 2.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) SET PF00856.28 KUM59106.1 - 0.086 13.2 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 SET domain DAO PF01266.24 KUM59107.1 - 4e-17 62.8 0.0 8.5e-17 61.8 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase AMP-binding PF00501.28 KUM59109.1 - 1.1e-63 215.4 0.0 1.5e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Aminotran_5 PF00266.19 KUM59109.1 - 3.8e-46 157.7 0.0 6.7e-46 156.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V NAD_binding_4 PF07993.12 KUM59109.1 - 9.7e-34 116.7 0.0 1.7e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KUM59109.1 - 8.6e-08 32.4 0.0 3.2e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KUM59109.1 - 7.1e-07 28.9 0.0 1.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Cys_Met_Meta_PP PF01053.20 KUM59109.1 - 0.0025 16.4 0.0 0.0075 14.8 0.0 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme AMP-binding_C PF13193.6 KUM59109.1 - 0.1 13.6 0.0 0.41 11.6 0.0 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain ATPgrasp_N PF18130.1 KUM59111.1 - 4.7e-17 62.3 0.0 1.1e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 KUM59111.1 - 1.8e-08 34.2 0.0 1e-07 31.7 0.0 2.3 2 1 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KUM59111.1 - 6.1e-05 22.7 0.0 0.00016 21.3 0.0 1.6 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KUM59111.1 - 0.016 15.3 0.0 0.52 10.3 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_Ter PF15632.6 KUM59111.1 - 0.2 11.4 0.0 5.5 6.7 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon LOH1CR12 PF10158.9 KUM59112.1 - 0.0091 16.0 0.0 3.6 7.6 0.0 2.7 2 0 0 2 2 2 2 Tumour suppressor protein Secretogranin_V PF05281.11 KUM59112.1 - 0.11 12.1 0.2 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) Glyco_hydro_16 PF00722.21 KUM59113.1 - 1.1e-09 38.0 0.0 3.6e-09 36.3 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 PHO4 PF01384.20 KUM59114.1 - 2.4e-117 391.8 12.0 2.7e-117 391.6 12.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family HLH PF00010.26 KUM59115.1 - 1.3e-07 31.4 0.1 2.4e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3509 PF12021.8 KUM59115.1 - 0.08 12.7 1.1 0.13 12.1 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) Nup54_57_C PF18570.1 KUM59115.1 - 0.17 11.5 1.6 0.31 10.6 1.6 1.4 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain CCDC106 PF15794.5 KUM59115.1 - 0.28 10.9 2.7 1.1 8.9 0.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 HisKA PF00512.25 KUM59115.1 - 0.28 11.2 2.3 1.3 9.1 0.1 2.2 1 1 1 2 2 2 0 His Kinase A (phospho-acceptor) domain C6 PF01681.17 KUM59116.1 - 0.0062 17.0 9.1 0.2 12.2 0.4 3.0 2 0 0 2 2 2 2 C6 domain Aminotran_5 PF00266.19 KUM59117.1 - 6e-28 97.8 0.0 7.8e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 KUM59117.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Metallophos_2 PF12850.7 KUM59118.1 - 6.9e-12 45.9 0.0 8.8e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GMC_oxred_N PF00732.19 KUM59119.1 - 4.3e-41 141.2 0.0 6.4e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM59119.1 - 6.8e-31 107.7 0.0 1.3e-30 106.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KUM59119.1 - 0.016 14.3 0.1 0.025 13.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Bin3 PF06859.12 KUM59120.1 - 3e-33 114.7 0.0 4.2e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 KUM59120.1 - 9.6e-13 48.3 0.0 1.3e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM59120.1 - 1.3e-11 44.6 0.0 1.6e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM59120.1 - 6.8e-10 39.5 0.0 1.2e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM59120.1 - 2.1e-09 37.9 0.0 4.2e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM59120.1 - 5.9e-07 30.2 0.0 1.1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KUM59120.1 - 9.4e-05 22.0 0.0 0.0003 20.4 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KUM59120.1 - 0.00073 19.0 0.1 0.0012 18.3 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KUM59120.1 - 0.0099 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KUM59120.1 - 0.082 12.5 0.0 2 8.0 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein 95 MFS_1 PF07690.16 KUM59121.1 - 2.6e-21 75.9 58.8 2.9e-21 75.8 14.3 3.7 1 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM59121.1 - 4.3e-10 38.6 10.6 8.6e-10 37.7 10.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM59121.1 - 1.8e-05 23.8 9.1 1.8e-05 23.8 9.1 3.4 1 1 0 3 3 3 1 Sugar (and other) transporter HHH PF00633.23 KUM59122.1 - 0.002 17.9 0.1 0.0042 16.9 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF202 PF02656.15 KUM59124.1 - 2.8e-13 50.1 4.4 2.8e-13 50.1 4.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5337 PF17272.2 KUM59124.1 - 1.8 8.5 7.3 0.57 10.1 3.5 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5337) Ank_2 PF12796.7 KUM59125.1 - 1.9e-19 70.0 0.2 9.6e-06 26.1 0.0 4.8 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM59125.1 - 5.1e-11 42.9 0.2 0.00072 20.1 0.0 5.5 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM59125.1 - 2.6e-10 39.6 0.9 0.63 10.8 0.0 6.4 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 KUM59125.1 - 3.3e-07 30.5 1.6 0.95 9.9 0.1 5.7 5 2 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 KUM59125.1 - 6.8e-06 26.3 2.0 13 6.5 0.0 6.0 7 0 0 7 7 7 2 Ankyrin repeat F-box-like PF12937.7 KUM59125.1 - 0.00047 20.0 0.0 0.00084 19.2 0.0 1.4 1 0 0 1 1 1 1 F-box-like Fungal_trans_2 PF11951.8 KUM59126.1 - 7.6e-05 21.7 0.4 0.0001 21.3 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_20 PF14561.6 KUM59126.1 - 0.19 12.1 0.0 0.47 10.8 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat GDA1_CD39 PF01150.17 KUM59127.1 - 2.3e-101 339.5 0.0 3e-101 339.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4598 PF15370.6 KUM59128.1 - 4.2e-34 117.3 16.1 1.3e-33 115.8 4.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4598) Macoilin PF09726.9 KUM59128.1 - 0.75 8.3 7.2 1.1 7.7 7.2 1.2 1 0 0 1 1 1 0 Macoilin family CCDC106 PF15794.5 KUM59128.1 - 1.1 8.9 9.8 0.15 11.8 4.0 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Fungal_trans_2 PF11951.8 KUM59129.1 - 6.6e-42 143.7 1.3 8.7e-42 143.3 1.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM59129.1 - 1.1e-07 31.8 8.9 2.1e-07 31.0 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 KUM59130.1 - 7.5e-56 189.3 0.2 8.6e-56 189.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM59130.1 - 7.9e-41 139.7 0.1 9.8e-41 139.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM59130.1 - 4.4e-10 39.8 0.8 6.3e-10 39.3 0.8 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KUM59130.1 - 0.00051 20.0 0.3 0.00097 19.1 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KUM59130.1 - 0.0044 16.4 0.7 0.011 15.0 0.7 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ChuX_HutX PF06228.13 KUM59130.1 - 0.01 15.6 0.1 0.81 9.5 0.0 2.5 1 1 1 2 2 2 0 Haem utilisation ChuX/HutX Epimerase PF01370.21 KUM59130.1 - 0.02 14.4 0.1 0.034 13.6 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KUM59130.1 - 0.033 13.3 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RecC_C PF17946.1 KUM59130.1 - 0.17 11.7 0.0 0.44 10.3 0.0 1.6 2 0 0 2 2 2 0 RecC C-terminal domain Aldedh PF00171.22 KUM59131.1 - 3e-132 441.4 0.0 3.3e-132 441.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Phage_HK97_TLTM PF06120.11 KUM59131.1 - 0.0019 17.4 0.1 0.0039 16.4 0.1 1.4 1 0 0 1 1 1 1 Tail length tape measure protein DUF1487 PF07368.11 KUM59131.1 - 0.0022 17.5 0.3 0.0073 15.8 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Cor1 PF04803.12 KUM59131.1 - 0.16 12.2 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region DnaB_bind PF10410.9 KUM59131.1 - 0.24 11.6 1.5 0.94 9.7 0.2 2.3 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase MFS_1 PF07690.16 KUM59132.1 - 5.9e-46 157.0 23.1 5.9e-46 157.0 23.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM59132.1 - 7e-15 54.8 0.3 7e-15 54.8 0.3 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KUM59132.1 - 1.2e-06 27.2 1.6 2.2e-06 26.4 1.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TRIQK PF15168.6 KUM59132.1 - 0.36 10.7 1.0 0.62 10.0 0.1 1.9 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Sugar_tr PF00083.24 KUM59133.1 - 2.8e-111 372.6 26.2 3.3e-111 372.4 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM59133.1 - 1e-18 67.4 39.0 4.2e-12 45.7 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_S6 PF01250.17 KUM59134.1 - 1.7e-21 76.3 0.0 2.1e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 zf-rbx1 PF12678.7 KUM59136.1 - 1.2e-08 35.1 2.2 3.2e-08 33.7 2.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KUM59136.1 - 5.4e-08 33.0 6.7 1.4e-07 31.7 2.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KUM59136.1 - 1.1e-06 28.4 0.7 2e-06 27.6 0.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KUM59136.1 - 3.6e-06 26.8 1.0 1e-05 25.4 1.0 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KUM59136.1 - 5.2e-06 26.2 7.6 6.6e-06 25.9 2.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KUM59136.1 - 0.00016 21.2 1.2 0.00085 18.9 0.6 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KUM59136.1 - 0.00033 20.5 1.2 0.00033 20.5 1.2 1.9 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KUM59136.1 - 0.00048 19.9 1.4 0.00048 19.9 1.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KUM59136.1 - 0.0016 18.1 11.2 0.012 15.3 0.3 3.6 4 0 0 4 4 4 2 RING-like zinc finger zf-RING_UBOX PF13445.6 KUM59136.1 - 0.002 18.1 2.0 0.002 18.1 2.0 3.5 2 1 1 3 3 3 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KUM59136.1 - 0.0082 16.2 1.1 0.023 14.8 1.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PQ-loop PF04193.14 KUM59136.1 - 0.02 14.7 2.5 0.45 10.3 0.3 2.8 2 0 0 2 2 2 0 PQ loop repeat DUF2921 PF11145.8 KUM59136.1 - 0.048 11.5 0.6 0.073 10.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-C3H2C3 PF17122.5 KUM59136.1 - 1.5 8.9 3.4 2.3 8.4 1.6 2.3 2 0 0 2 2 2 0 Zinc-finger FANCL_C PF11793.8 KUM59136.1 - 3 8.1 5.1 3.2 8.0 2.8 2.1 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 KUM59136.1 - 5.6 7.2 7.0 0.55 10.4 1.6 2.0 2 0 0 2 2 2 0 RING-variant domain COMPASS-Shg1 PF05205.12 KUM59137.1 - 3.3e-26 92.0 0.0 3.3e-26 92.0 0.0 2.2 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF1672 PF07901.11 KUM59137.1 - 0.0089 15.4 0.4 0.014 14.7 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1672) Gln-synt_C PF00120.24 KUM59139.1 - 4.4e-78 262.7 0.0 8.8e-78 261.7 0.0 1.5 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 KUM59139.1 - 0.18 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain GATase PF00117.28 KUM59140.1 - 7.7e-15 55.1 0.0 1.1e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KUM59140.1 - 2.1e-05 24.4 0.0 0.00056 19.7 0.0 2.7 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 KUM59140.1 - 2.6e-05 23.9 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 KUM59140.1 - 0.00018 21.4 0.0 0.00025 20.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family SNO PF01174.19 KUM59140.1 - 0.039 13.8 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Lipase_GDSL_2 PF13472.6 KUM59141.1 - 1.4e-06 28.8 0.1 2.5e-06 28.0 0.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KUM59141.1 - 1.2e-05 25.4 0.0 1.3e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Fungal_trans PF04082.18 KUM59142.1 - 0.00036 19.7 0.1 0.00091 18.3 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain TPR_MalT PF17874.1 KUM59142.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 MalT-like TPR region IF3_N PF05198.16 KUM59143.1 - 1.2e-10 41.5 0.0 2.4e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 KUM59143.1 - 7.4e-09 35.5 0.6 1.4e-08 34.5 0.6 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 KUM59143.1 - 1.9e-05 24.4 1.0 3e-05 23.8 1.0 1.3 1 0 0 1 1 1 1 Mitochondrial translation initiation factor GTP_EFTU PF00009.27 KUM59144.1 - 9.9e-58 194.9 0.1 1.4e-57 194.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KUM59144.1 - 1.5e-20 73.5 0.0 2.9e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KUM59144.1 - 1.6e-17 63.6 1.7 1.6e-17 63.6 1.7 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KUM59144.1 - 8.4e-06 25.9 0.1 1.8e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KUM59144.1 - 0.0021 18.0 0.2 0.0074 16.2 0.0 1.8 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 KUM59144.1 - 0.044 13.4 0.2 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KUM59144.1 - 0.054 13.2 0.1 8.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Cation_efflux PF01545.21 KUM59146.1 - 2.7e-13 50.1 9.9 3.7e-13 49.7 9.9 1.1 1 0 0 1 1 1 1 Cation efflux family RHD3 PF05879.12 KUM59147.1 - 0 1058.9 0.0 0 1058.6 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KUM59147.1 - 9.1e-07 28.4 0.2 1.5e-06 27.7 0.2 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KUM59147.1 - 6e-06 26.4 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KUM59147.1 - 0.00076 19.5 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KUM59147.1 - 0.0017 18.6 0.9 0.0033 17.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Phi_1 PF04674.12 KUM59147.1 - 0.066 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region Cyclase PF04199.13 KUM59148.1 - 7.9e-10 39.1 0.0 3.3e-09 37.1 0.0 1.7 1 1 1 2 2 2 1 Putative cyclase DUF5490 PF17593.2 KUM59148.1 - 0.043 13.8 0.7 0.1 12.6 0.0 1.9 3 0 0 3 3 3 0 Family of unknown function (DUF5490) GCV_H PF01597.19 KUM59149.1 - 9.8e-36 122.3 2.0 1.2e-35 122.0 2.0 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 KUM59149.1 - 0.09 12.6 1.0 1.8 8.5 0.3 2.2 1 1 1 2 2 2 0 Biotin-requiring enzyme DUF3128 PF11326.8 KUM59150.1 - 3.8 7.9 8.6 2.4e+02 2.2 8.5 3.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Oxidored_FMN PF00724.20 KUM59152.1 - 1e-92 311.1 0.0 1.2e-92 310.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GRDA PF04723.14 KUM59152.1 - 0.019 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A DUF1848 PF08902.11 KUM59152.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Gpr1_Fun34_YaaH PF01184.19 KUM59153.1 - 1.5e-88 295.8 17.3 1.8e-88 295.6 17.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Fungal_trans_2 PF11951.8 KUM59154.1 - 1e-11 44.3 0.0 4.6e-11 42.2 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAM199X PF15814.5 KUM59154.1 - 0.0073 15.4 1.0 0.013 14.6 1.0 1.3 1 0 0 1 1 1 1 Protein family FAM199X Glyco_hydro_71 PF03659.14 KUM59155.1 - 1.6e-53 181.9 5.4 1.9e-53 181.6 5.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.6 KUM59155.1 - 0.061 13.3 0.1 0.094 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Memo PF01875.17 KUM59156.1 - 1.5e-36 125.9 0.0 1.9e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein MFS_1 PF07690.16 KUM59157.1 - 3.7e-36 124.8 22.1 5e-36 124.4 22.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM59157.1 - 3.9e-13 49.1 4.5 3.9e-13 49.1 4.5 1.7 2 1 0 2 2 2 1 Sugar (and other) transporter WD40 PF00400.32 KUM59159.1 - 4e-20 71.8 12.7 0.00019 22.2 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM59159.1 - 3.4e-17 62.5 0.0 6e-07 29.7 0.0 5.5 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KUM59159.1 - 1.5e-05 24.9 0.5 0.018 14.9 0.0 2.6 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KUM59159.1 - 0.001 18.1 0.1 4.2 6.2 0.0 3.9 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein HIRA_B PF09453.10 KUM59159.1 - 0.0017 18.2 0.4 0.0017 18.2 0.4 2.6 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.12 KUM59159.1 - 0.044 13.7 5.8 8.1 6.5 0.2 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KUM59159.1 - 0.11 11.8 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain Glyco_transf_20 PF00982.21 KUM59160.1 - 3.7e-143 477.6 0.0 1.3e-142 475.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KUM59160.1 - 3.5e-27 95.0 0.0 5.5e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase T5orf172 PF10544.9 KUM59161.1 - 7.1e-16 58.6 1.2 1.8e-15 57.3 1.2 1.7 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KUM59161.1 - 1.2e-05 25.9 1.8 2.2e-05 25.0 1.8 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 TarS_C1 PF18674.1 KUM59161.1 - 0.033 14.1 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 TarS beta-glycosyltransferase C-terminal domain 1 GIY-YIG PF01541.24 KUM59161.1 - 0.047 14.0 0.1 0.095 13.0 0.1 1.6 1 0 0 1 1 1 0 GIY-YIG catalytic domain Glyco_hydro_71 PF03659.14 KUM59162.1 - 2.8e-28 98.8 0.0 3.3e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Transglut_core PF01841.19 KUM59164.1 - 4.7e-14 52.8 2.3 1.1e-13 51.6 2.3 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 KUM59164.1 - 1.3e-13 50.9 2.8 2.3e-13 50.1 2.8 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain IPTL-CTERM PF18203.1 KUM59166.1 - 0.35 10.8 0.3 0.35 10.8 0.3 2.0 2 0 0 2 2 2 0 IPTL-CTERM motif DASH_Spc34 PF08657.10 KUM59167.1 - 2.1e-42 145.7 0.6 1.1e-21 77.8 0.1 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 DASH_Spc19 PF08287.11 KUM59167.1 - 0.0079 16.1 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 Spc19 Spectrin PF00435.21 KUM59167.1 - 0.068 13.7 0.2 7.3 7.1 0.1 2.5 3 0 0 3 3 3 0 Spectrin repeat DUF3381 PF11861.8 KUM59167.1 - 0.082 12.7 0.1 0.32 10.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) ATP-sulfurylase PF01747.17 KUM59168.1 - 5.7e-86 287.4 0.0 8e-86 286.9 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KUM59168.1 - 4.5e-60 202.1 0.0 6.9e-60 201.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KUM59168.1 - 7.4e-52 175.2 0.0 1.3e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_18 PF13238.6 KUM59168.1 - 0.052 14.1 0.0 0.15 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain EGF PF00008.27 KUM59169.1 - 0.25 11.7 6.4 0.48 10.8 6.4 1.5 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.13 KUM59169.1 - 2.7 8.5 12.7 5.4 7.5 12.7 1.5 1 0 0 1 1 1 0 EGF-like domain DASH_Spc19 PF08287.11 KUM59170.1 - 0.0072 16.2 0.6 0.011 15.6 0.1 1.5 2 0 0 2 2 2 1 Spc19 Bcl-2_BAD PF10514.9 KUM59170.1 - 0.021 15.3 0.1 0.025 15.1 0.1 1.2 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD Toxin-deaminase PF14424.6 KUM59170.1 - 0.12 12.5 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases Complex1_LYR PF05347.15 KUM59171.1 - 2.5e-16 59.5 5.0 2.5e-16 59.5 5.0 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KUM59171.1 - 3.1e-05 24.6 1.3 3.6e-05 24.4 1.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like VitD-bind_III PF09164.10 KUM59171.1 - 0.062 13.3 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Vitamin D binding protein, domain III SET PF00856.28 KUM59172.1 - 9.4e-12 45.6 0.2 9.4e-12 45.6 0.2 3.6 3 1 0 3 3 3 1 SET domain AWS PF17907.1 KUM59172.1 - 1.8e-08 34.3 9.3 1.8e-08 34.3 9.3 2.5 3 0 0 3 3 3 1 AWS domain polyprenyl_synt PF00348.17 KUM59173.1 - 3.4e-72 242.6 0.0 6.6e-72 241.6 0.0 1.4 1 1 0 1 1 1 1 Polyprenyl synthetase HMG_box PF00505.19 KUM59174.1 - 7.9e-20 71.0 0.0 1.2e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KUM59174.1 - 0.002 18.7 0.0 0.0033 18.0 0.0 1.3 1 0 0 1 1 1 1 HMG-box domain Exo_endo_phos PF03372.23 KUM59175.1 - 5.3e-09 35.9 0.0 1.1e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KUM59175.1 - 4.8e-05 23.4 0.2 0.00012 22.1 0.2 1.7 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 KUM59175.1 - 0.00044 20.1 0.1 0.69 9.8 0.0 2.9 3 0 0 3 3 3 2 Endonuclease-reverse transcriptase COX6A PF02046.15 KUM59176.1 - 2.6e-53 179.3 1.4 3.6e-53 178.8 1.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa PAPS_reduct PF01507.19 KUM59177.1 - 0.047 13.7 0.1 0.075 13.1 0.1 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Rpn3_C PF08375.11 KUM59178.1 - 5.4e-27 94.0 1.2 1.8e-26 92.3 1.2 2.0 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KUM59178.1 - 1.5e-19 70.4 0.2 7.2e-19 68.2 0.0 2.2 2 0 0 2 2 2 1 PCI domain ABATE PF07336.11 KUM59178.1 - 0.048 14.3 2.5 1.2 9.9 0.2 2.5 2 0 0 2 2 2 0 Putative stress-induced transcription regulator Sigma70_r1_2 PF00140.20 KUM59178.1 - 1.1 9.3 5.2 0.96 9.5 2.4 2.3 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 MSA_2 PF00985.17 KUM59178.1 - 1.2 9.5 17.0 2.1 8.6 17.0 1.3 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family MMM1 PF10296.9 KUM59179.1 - 0.00018 20.7 0.0 0.00033 19.8 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 KUM59179.1 - 0.099 13.1 0.0 0.31 11.5 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain EURL PF06937.11 KUM59179.1 - 0.16 11.4 0.2 0.26 10.7 0.2 1.2 1 0 0 1 1 1 0 EURL protein ANTH PF07651.16 KUM59180.1 - 3.7e-79 265.6 0.0 3.7e-79 265.6 0.0 2.8 2 1 2 4 4 4 1 ANTH domain I_LWEQ PF01608.17 KUM59180.1 - 2.1e-55 187.1 4.9 2.1e-55 187.1 4.9 6.2 3 2 2 6 6 6 2 I/LWEQ domain PARP PF00644.20 KUM59181.1 - 3.8e-10 39.7 0.1 1.1e-09 38.2 0.1 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KUM59181.1 - 5.9e-07 29.2 0.0 1.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Seipin PF06775.14 KUM59183.1 - 6.2e-62 209.2 0.1 9.3e-62 208.6 0.1 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) TTL PF03133.15 KUM59184.1 - 7.2e-56 189.5 0.0 1.1e-55 188.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 KUM59184.1 - 2.1e-50 171.2 0.0 3.2e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 KUM59184.1 - 4.5e-05 22.8 0.0 0.00023 20.5 0.0 1.9 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KUM59184.1 - 0.025 13.8 0.0 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Glyco_trans_4_4 PF13579.6 KUM59184.1 - 0.058 13.8 0.0 0.19 12.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Dala_Dala_lig_C PF07478.13 KUM59184.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Not1 PF04054.15 KUM59186.1 - 1.3e-140 468.5 0.2 2.5e-140 467.6 0.2 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KUM59186.1 - 2.5e-95 318.2 0.3 6.7e-95 316.7 0.3 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KUM59186.1 - 6e-52 175.5 1.7 1.5e-51 174.2 1.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KUM59186.1 - 2.5e-41 141.0 0.0 7.3e-41 139.4 0.0 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KUM59186.1 - 8.9e-29 100.5 1.2 6.2e-28 97.8 0.1 2.9 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Zemlya PF17646.1 KUM59186.1 - 0.11 12.9 0.1 0.35 11.3 0.1 1.9 1 0 0 1 1 1 0 Closterovirus 1a polyprotein central region DUF3169 PF11368.8 KUM59187.1 - 0.0097 15.4 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) Ndc80_HEC PF03801.13 KUM59189.1 - 1.6e-59 199.9 0.0 3.7e-59 198.8 0.0 1.7 1 0 0 1 1 1 1 HEC/Ndc80p family Filament PF00038.21 KUM59189.1 - 0.00012 21.7 18.3 0.00012 21.7 18.3 2.5 2 0 0 2 2 2 2 Intermediate filament protein CENP-F_leu_zip PF10473.9 KUM59189.1 - 0.00025 21.1 9.7 0.00025 21.1 9.7 4.2 2 2 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF16 PF01519.16 KUM59189.1 - 0.023 15.2 6.7 0.023 15.2 6.7 3.7 2 2 2 4 4 4 0 Protein of unknown function DUF16 Jnk-SapK_ap_N PF09744.9 KUM59189.1 - 1.2 9.4 44.8 0.39 10.9 7.3 3.4 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 KUM59189.1 - 2.6 8.1 42.8 0.53 10.4 12.4 4.4 3 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 KUM59189.1 - 3.9 7.8 7.3 5.8 7.2 0.6 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper NPV_P10 PF05531.12 KUM59189.1 - 8 7.0 14.7 19 5.8 0.3 4.3 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 KUM59189.1 - 9.1 5.1 43.0 1.7 7.5 10.5 3.3 2 2 1 3 3 3 0 Spc7 kinetochore protein PrpF PF04303.13 KUM59190.1 - 6.9e-104 347.7 0.4 8.1e-104 347.5 0.4 1.0 1 0 0 1 1 1 1 PrpF protein DUF3246 PF11596.8 KUM59191.1 - 0.039 13.4 0.7 0.052 13.0 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Fungal_trans PF04082.18 KUM59192.1 - 8.2e-18 64.4 0.0 1.3e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pex14_N PF04695.13 KUM59193.1 - 0.0016 19.2 1.4 0.0016 19.2 1.4 3.4 2 1 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.12 KUM59193.1 - 0.0025 17.8 1.8 0.029 14.4 1.9 2.3 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 KUM59193.1 - 0.0065 14.1 4.2 0.0084 13.7 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 KUM59193.1 - 0.011 15.2 0.7 0.016 14.7 0.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1043 PF06295.12 KUM59193.1 - 0.048 13.6 0.1 0.091 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) LMBR1 PF04791.16 KUM59193.1 - 0.15 10.9 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4211 PF13926.6 KUM59193.1 - 0.18 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) DUF812 PF05667.11 KUM59193.1 - 0.25 10.2 3.6 0.58 9.0 3.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Prominin PF05478.11 KUM59193.1 - 0.25 9.2 0.1 0.32 8.9 0.1 1.1 1 0 0 1 1 1 0 Prominin ERM PF00769.19 KUM59193.1 - 0.39 10.5 8.6 0.14 12.0 4.3 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family zf-C4H2 PF10146.9 KUM59193.1 - 1.4 9.1 7.7 4.5 7.5 7.7 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein DUF1664 PF07889.12 KUM59193.1 - 7 6.7 6.9 0.37 10.8 0.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) PT PF04886.12 KUM59194.1 - 0.9 9.1 45.7 0.15 11.6 7.8 4.2 3 1 0 3 3 3 0 PT repeat HNH_2 PF13391.6 KUM59197.1 - 8.9e-06 25.8 0.0 4.4e-05 23.5 0.0 2.2 2 1 0 2 2 2 1 HNH endonuclease G-7-MTase PF12803.7 KUM59197.1 - 0.012 14.8 1.1 0.024 13.8 1.1 1.4 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Sacchrp_dh_C PF16653.5 KUM59198.1 - 1.3e-82 277.8 0.0 1.8e-82 277.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KUM59198.1 - 3.6e-21 75.8 1.0 1.4e-20 73.9 0.8 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KUM59198.1 - 1.1e-07 32.0 1.8 1.5e-07 31.5 0.1 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Catalase_C PF18011.1 KUM59198.1 - 0.002 17.7 0.2 0.0034 17.0 0.2 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases IlvN PF07991.12 KUM59198.1 - 0.01 15.4 0.7 0.22 11.1 0.1 2.7 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 KUM59198.1 - 0.02 15.1 0.0 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 KUM59198.1 - 0.043 14.3 0.3 0.085 13.3 0.3 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KUM59198.1 - 0.061 12.6 0.8 0.11 11.8 0.8 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2325 PF10087.9 KUM59198.1 - 0.19 11.9 0.1 0.83 9.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) Sugar_tr PF00083.24 KUM59199.1 - 2e-86 290.6 27.5 2.5e-86 290.3 27.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM59199.1 - 3.3e-17 62.5 25.5 3.3e-17 62.5 25.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KUM59201.1 - 8.3e-25 87.4 0.0 1.4e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 5-FTHF_cyc-lig PF01812.20 KUM59202.1 - 9.8e-41 139.7 0.0 1.1e-40 139.5 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family ATP-grasp_6 PF18419.1 KUM59202.1 - 0.054 13.1 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp-like domain Amidohydro_2 PF04909.14 KUM59203.1 - 2.9e-37 129.0 1.7 2.9e-37 129.0 1.7 1.6 1 1 1 2 2 2 1 Amidohydrolase Acid_PPase PF12689.7 KUM59203.1 - 0.015 15.1 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Acid Phosphatase Trypan_PARP PF05887.11 KUM59204.1 - 0.29 11.1 8.3 0.49 10.4 8.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RINGv PF12906.7 KUM59205.1 - 6e-09 35.9 5.0 9.1e-09 35.3 1.4 2.3 2 0 0 2 2 2 1 RING-variant domain zf-BED PF02892.15 KUM59205.1 - 0.08 13.0 0.3 0.08 13.0 0.3 1.9 2 0 0 2 2 2 0 BED zinc finger zf-RING_2 PF13639.6 KUM59205.1 - 0.24 11.7 4.6 1.2 9.6 1.7 2.2 2 0 0 2 2 2 0 Ring finger domain PHD PF00628.29 KUM59205.1 - 0.61 10.0 5.3 0.21 11.5 2.3 1.7 2 0 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 KUM59205.1 - 1.8 8.7 5.6 7.3 6.8 5.7 1.9 1 1 1 2 2 2 0 PHD-finger Proteasome PF00227.26 KUM59206.1 - 6.9e-57 192.0 0.0 7.2e-32 110.4 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KUM59206.1 - 8.8e-11 41.3 0.1 3.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.15 KUM59206.1 - 0.052 12.3 0.1 0.73 8.5 0.0 2.0 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Rad51 PF08423.11 KUM59208.1 - 3.3e-11 42.9 0.0 2.5e-05 23.7 0.0 2.6 2 1 0 2 2 2 2 Rad51 RecA PF00154.21 KUM59208.1 - 1.1e-06 28.4 0.0 8.4e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein ATPase PF06745.13 KUM59208.1 - 2.9e-05 23.5 0.0 6.2e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 KUM59208.1 - 5.8e-05 22.8 0.0 0.00023 20.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KUM59208.1 - 0.0011 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 KUM59208.1 - 0.0026 17.3 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 KUM59208.1 - 0.019 15.4 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KUM59208.1 - 0.047 14.1 0.2 0.35 11.2 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KUM59208.1 - 0.064 13.8 0.1 0.14 12.7 0.1 1.5 1 0 0 1 1 1 0 ABC transporter KdpD PF02702.17 KUM59208.1 - 0.089 12.2 0.0 2.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain DnaB_C PF03796.15 KUM59208.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KUM59208.1 - 0.23 11.2 0.1 0.6 9.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain MOSC PF03473.17 KUM59209.1 - 6.8e-23 81.1 0.0 1e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KUM59209.1 - 2.7e-07 30.5 0.0 4.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Xan_ur_permease PF00860.20 KUM59211.1 - 3.5e-63 213.6 30.6 9.3e-63 212.2 30.6 1.6 1 1 0 1 1 1 1 Permease family FA_desaturase PF00487.24 KUM59213.1 - 4.2e-20 72.6 12.9 4.2e-20 72.6 12.9 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KUM59213.1 - 1.6e-16 60.2 0.2 4.7e-16 58.7 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF2225 PF09986.9 KUM59213.1 - 0.014 15.2 0.0 0.035 13.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF1189 PF06691.11 KUM59213.1 - 0.061 12.9 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) MHC_I PF00129.18 KUM59214.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 PEHE PF15275.6 KUM59215.1 - 0.03 15.0 2.0 0.03 15.0 2.0 1.8 2 0 0 2 2 2 0 PEHE domain Xpo1 PF08389.12 KUM59218.1 - 2.7e-27 95.7 0.5 7.6e-26 91.0 0.0 3.2 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KUM59218.1 - 1.5e-05 24.8 0.0 7.5e-05 22.6 0.0 2.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Fungal_trans PF04082.18 KUM59219.1 - 1.3e-65 221.2 0.0 1.7e-65 220.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_7 PF13499.6 KUM59219.1 - 1.8e-09 37.9 0.4 9.8e-07 29.1 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KUM59219.1 - 2.9e-07 30.7 0.0 0.016 15.5 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 KUM59219.1 - 1.3e-05 24.8 1.1 0.17 11.9 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain zf-C2H2 PF00096.26 KUM59219.1 - 3.7e-05 24.0 11.9 0.0017 18.7 0.8 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type EF-hand_1 PF00036.32 KUM59219.1 - 0.00013 21.2 0.2 0.29 10.8 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KUM59219.1 - 0.00034 20.4 0.1 0.0018 18.0 0.1 2.2 3 0 0 3 3 3 1 EF-hand domain pair zf-H2C2_2 PF13465.6 KUM59219.1 - 0.027 14.9 6.2 0.032 14.6 1.6 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KUM59219.1 - 0.42 11.6 13.9 0.11 13.5 0.8 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Peptidase_M3 PF01432.20 KUM59220.1 - 4.1e-162 540.6 0.0 6.7e-162 539.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 SUV3_C PF12513.8 KUM59220.1 - 0.023 14.6 0.1 0.064 13.2 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal AA_permease_2 PF13520.6 KUM59221.1 - 5.8e-62 209.9 47.2 7e-62 209.6 47.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM59221.1 - 1.6e-22 79.8 42.9 2.1e-22 79.4 42.9 1.1 1 0 0 1 1 1 1 Amino acid permease Epiglycanin_C PF14654.6 KUM59221.1 - 0.22 11.6 0.1 0.22 11.6 0.1 2.4 2 1 1 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region DUF5480 PF17576.2 KUM59221.1 - 0.28 11.2 3.7 2.5 8.1 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5480) Zn_clus PF00172.18 KUM59222.1 - 4.2e-05 23.6 7.4 7.7e-05 22.7 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suppressor_P21 PF11479.8 KUM59222.1 - 0.049 13.8 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA silencing suppressor P21 C-terminal domain zf-PHD-like PF15446.6 KUM59222.1 - 0.29 10.7 5.1 0.6 9.7 5.1 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain GST_N_2 PF13409.6 KUM59223.1 - 1.5e-17 63.6 0.0 4.3e-17 62.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KUM59223.1 - 2.6e-10 40.2 0.0 6.7e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KUM59223.1 - 0.0024 18.0 0.0 0.0044 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KUM59223.1 - 0.012 16.0 0.0 4.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Hyccin PF09790.9 KUM59224.1 - 0.011 14.9 0.2 0.029 13.5 0.0 1.8 2 0 0 2 2 2 0 Hyccin adh_short PF00106.25 KUM59225.1 - 2.8e-25 88.9 0.1 4e-25 88.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM59225.1 - 1.1e-24 87.3 0.1 1.3e-24 87.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM59225.1 - 1.8e-09 37.8 0.2 4.2e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KUM59225.1 - 5.6e-09 36.2 0.7 1.5e-08 34.8 0.7 1.8 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KUM59225.1 - 1e-05 25.2 0.1 2e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 KUM59225.1 - 0.0011 19.3 0.4 0.0035 17.6 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.19 KUM59225.1 - 0.021 13.9 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PseudoU_synth_2 PF00849.22 KUM59225.1 - 0.041 14.0 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA pseudouridylate synthase Cys_Met_Meta_PP PF01053.20 KUM59226.1 - 5e-149 496.0 0.0 5.7e-149 495.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KUM59226.1 - 5.6e-10 39.1 0.7 9.4e-10 38.3 0.4 1.4 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KUM59226.1 - 7.2e-09 35.3 0.1 1.2e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KUM59226.1 - 1.7e-08 33.9 0.2 2.6e-08 33.3 0.2 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KUM59226.1 - 9.1e-07 28.4 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KUM59226.1 - 7.5e-05 21.4 0.1 0.0001 21.0 0.1 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Asparaginase_C PF17763.1 KUM59226.1 - 0.0063 16.7 0.1 0.018 15.2 0.0 1.8 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain GDC-P PF02347.16 KUM59226.1 - 0.073 11.9 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Pyr_redox_3 PF13738.6 KUM59227.1 - 4.7e-18 65.5 0.0 7.2e-16 58.3 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM59227.1 - 7.9e-14 51.6 0.0 1.6e-11 44.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KUM59227.1 - 3.1e-11 42.4 0.2 1.4e-08 33.7 0.1 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KUM59227.1 - 1.1e-08 34.6 0.1 1.1e-06 28.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KUM59227.1 - 4.9e-06 26.7 0.0 2.7e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KUM59227.1 - 2.2e-05 23.9 0.1 4e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KUM59227.1 - 0.00091 18.4 0.2 0.0017 17.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KUM59227.1 - 0.0018 18.8 0.2 4 8.1 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KUM59227.1 - 0.0022 16.8 0.1 0.0061 15.3 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KUM59227.1 - 0.0048 16.2 0.0 0.1 11.9 0.0 2.3 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 KUM59227.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KUM59227.1 - 0.028 13.8 0.1 0.18 11.1 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KUM59227.1 - 0.047 12.8 0.5 0.45 9.5 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Citrate_synt PF00285.21 KUM59228.1 - 7.4e-100 334.5 0.0 9.3e-100 334.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain CTD_bind PF04818.13 KUM59229.1 - 2.1e-08 34.9 0.0 3.8e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KUM59229.1 - 1.2e-05 25.1 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 KUM59230.1 - 1.2e-14 54.3 0.0 1.9e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PD40 PF07676.12 KUM59230.1 - 3.5e-12 45.9 4.4 1.2 9.2 0.0 7.3 7 0 0 7 7 7 4 WD40-like Beta Propeller Repeat WD40 PF00400.32 KUM59230.1 - 5.2e-10 39.8 2.4 0.95 10.4 0.0 6.3 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM59230.1 - 2.1e-07 31.2 0.0 0.28 11.5 0.0 5.0 1 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KUM59230.1 - 4.8e-05 22.8 0.1 0.36 10.1 0.0 3.2 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Pkinase_Tyr PF07714.17 KUM59230.1 - 0.0027 17.0 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ge1_WD40 PF16529.5 KUM59230.1 - 0.018 14.0 0.0 0.47 9.3 0.0 3.1 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3748 PF12566.8 KUM59230.1 - 0.13 12.2 0.0 5.6 6.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3748) DPPIV_N PF00930.21 KUM59230.1 - 0.15 10.8 0.0 15 4.2 0.0 3.3 2 2 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.9 KUM59230.1 - 7.7 6.3 0.0 7.7 6.3 0.0 4.1 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature RNA_pol_Rpc82 PF05645.13 KUM59231.1 - 2.2e-24 86.6 0.0 7e-20 71.9 0.0 2.6 2 1 1 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KUM59231.1 - 5.1e-17 61.7 1.6 2.2e-09 37.3 0.1 3.8 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KUM59231.1 - 0.00053 19.8 0.3 0.0053 16.6 0.0 2.5 2 1 1 3 3 3 1 TFIIE alpha subunit Peptidase_M16 PF00675.20 KUM59232.1 - 2.8e-19 69.6 0.0 5.8e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KUM59232.1 - 5.1e-14 52.7 0.0 1.1e-13 51.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 KUM59232.1 - 0.0014 17.8 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated DUF530 PF04409.12 KUM59232.1 - 0.062 11.7 0.2 0.1 11.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF530) Bac_DNA_binding PF00216.21 KUM59232.1 - 1.2 9.4 4.7 14 6.0 0.2 2.8 3 0 0 3 3 3 0 Bacterial DNA-binding protein Septin PF00735.18 KUM59233.1 - 2.1e-14 53.5 0.0 1.2e-13 51.1 0.0 1.9 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KUM59233.1 - 0.011 15.8 0.0 0.039 14.0 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KUM59233.1 - 0.016 15.6 0.0 0.04 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KUM59233.1 - 0.016 15.3 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KUM59233.1 - 0.018 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 KUM59233.1 - 0.026 15.1 0.0 0.055 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 KUM59233.1 - 0.032 14.0 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 KUM59233.1 - 0.032 14.1 0.0 0.38 10.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF815 PF05673.13 KUM59233.1 - 0.046 12.9 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 KUM59233.1 - 0.068 13.1 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 KUM59233.1 - 0.068 13.4 0.6 0.26 11.5 0.1 2.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 KUM59233.1 - 0.078 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KUM59233.1 - 0.08 12.5 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KUM59233.1 - 0.085 13.3 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KUM59233.1 - 0.11 12.1 0.1 0.98 9.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 KUM59233.1 - 0.13 11.4 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 KUM59233.1 - 0.13 12.0 1.3 0.21 11.3 0.3 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KUM59233.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Dynamin_N PF00350.23 KUM59233.1 - 0.16 12.0 0.0 29 4.7 0.1 2.7 3 0 0 3 3 3 0 Dynamin family Gtr1_RagA PF04670.12 KUM59233.1 - 0.18 11.2 0.1 0.43 9.9 0.0 1.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region TsaE PF02367.17 KUM59233.1 - 0.18 11.8 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KUM59233.1 - 0.21 11.3 0.0 0.48 10.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain HLH PF00010.26 KUM59234.1 - 1.2e-11 44.4 2.4 2.2e-11 43.5 2.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1082 PF06449.11 KUM59234.1 - 0.096 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1082) Sugar_tr PF00083.24 KUM59235.1 - 1.7e-79 267.8 17.5 2e-79 267.6 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM59235.1 - 3.7e-20 72.2 36.5 3.5e-13 49.2 14.7 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 KUM59235.1 - 0.0011 17.9 2.9 0.0011 17.9 2.9 2.4 2 1 0 2 2 2 1 MFS_1 like family Mito_carr PF00153.27 KUM59236.1 - 1.1e-26 92.6 2.6 6.4e-12 45.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3328 PF11807.8 KUM59237.1 - 1.3e-53 182.0 0.0 1.7e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) C-C_Bond_Lyase PF15617.6 KUM59237.1 - 0.21 10.7 0.0 0.32 10.1 0.0 1.1 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold DUF2582 PF10771.9 KUM59238.1 - 0.093 12.9 0.1 0.61 10.3 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix domain (DUF2582) Transp_cyt_pur PF02133.15 KUM59239.1 - 2.3e-13 49.7 13.4 3e-13 49.4 13.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pox_A28 PF04584.14 KUM59239.1 - 0.44 10.7 3.8 1.8 8.8 3.8 1.8 2 0 0 2 2 2 0 Poxvirus A28 family Asp PF00026.23 KUM59240.1 - 3.6e-42 144.9 4.7 4.4e-42 144.6 4.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KUM59240.1 - 0.00024 21.4 0.6 0.0021 18.3 0.6 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KUM59240.1 - 0.004 17.0 0.1 0.0073 16.1 0.1 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KUM59240.1 - 0.028 15.0 0.1 0.36 11.5 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 KUM59240.1 - 0.09 13.3 0.2 1.9 9.1 0.0 3.1 4 1 0 4 4 4 0 gag-polyprotein putative aspartyl protease SLBP_RNA_bind PF15247.6 KUM59240.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain Fungal_trans PF04082.18 KUM59241.1 - 1.2e-13 50.8 0.4 3.5e-13 49.2 0.1 1.7 1 1 0 2 2 2 1 Fungal specific transcription factor domain ADH_zinc_N_2 PF13602.6 KUM59242.1 - 6.1e-14 53.2 0.0 1.2e-13 52.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KUM59242.1 - 2.1e-11 43.9 0.2 2.1e-11 43.9 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM59242.1 - 4.2e-08 33.1 0.0 5.9e-05 22.9 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 KUM59242.1 - 0.015 15.2 0.4 0.14 12.0 0.2 2.1 2 0 0 2 2 2 0 NAD(P)H-binding Acetyltransf_3 PF13302.7 KUM59243.1 - 1.6e-21 77.4 0.0 1.9e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM59243.1 - 1.2e-06 28.8 0.0 1.8e-06 28.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KUM59243.1 - 0.023 14.7 0.0 0.07 13.1 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_8 PF13523.6 KUM59243.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ORF6C PF10552.9 KUM59244.1 - 0.017 15.2 0.1 0.04 14.0 0.0 1.6 2 0 0 2 2 2 0 ORF6C domain adh_short PF00106.25 KUM59246.1 - 1.1e-38 132.7 0.0 1.5e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM59246.1 - 3.2e-37 128.3 0.1 3.8e-33 115.0 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM59246.1 - 1.4e-14 54.4 0.1 1.1e-13 51.6 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KUM59246.1 - 0.00026 20.5 0.1 0.0034 16.9 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PEP-utilisers_N PF05524.13 KUM59246.1 - 0.077 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Sugar_tr PF00083.24 KUM59247.1 - 3.6e-96 322.8 21.9 4.2e-96 322.5 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM59247.1 - 2.7e-29 102.2 61.7 1.1e-26 93.6 32.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KUM59247.1 - 4.3e-06 25.3 13.9 9.9e-06 24.1 1.3 2.9 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family YqhR PF11085.8 KUM59247.1 - 0.0063 16.5 0.4 0.16 11.9 0.2 2.5 2 0 0 2 2 2 1 Conserved membrane protein YqhR FMN_dh PF01070.18 KUM59249.1 - 2.9e-76 256.7 2.4 3.9e-75 253.1 2.4 1.9 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KUM59249.1 - 2.6e-06 26.8 0.1 3.9e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KUM59249.1 - 5.8e-05 22.3 0.7 0.00011 21.3 0.5 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KUM59249.1 - 0.0083 15.6 1.1 0.013 15.0 1.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KUM59249.1 - 0.032 13.6 0.1 1.1 8.5 0.1 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KUM59249.1 - 0.033 13.7 0.0 0.081 12.4 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.21 KUM59249.1 - 0.063 12.5 0.0 0.24 10.6 0.1 1.8 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Sugar_tr PF00083.24 KUM59250.1 - 2.4e-93 313.5 27.4 2.8e-93 313.3 27.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM59250.1 - 1e-37 129.9 50.1 7.1e-32 110.7 22.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KUM59251.1 - 6.4e-24 84.4 1.1 1e-23 83.8 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KUM59252.1 - 2.1e-52 178.0 0.1 2.7e-52 177.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM59252.1 - 8.7e-44 149.3 0.1 1e-43 149.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM59252.1 - 1.1e-08 35.2 0.1 1.7e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KUM59252.1 - 0.049 13.0 0.1 0.096 12.0 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 KUM59252.1 - 0.19 11.1 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Mannosidase_ig PF17786.1 KUM59254.1 - 3.7e-14 53.1 0.0 1e-13 51.7 0.0 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KUM59254.1 - 2.2e-05 25.1 0.0 0.00011 22.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KUM59254.1 - 0.00027 20.1 0.1 0.0005 19.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KUM59254.1 - 0.024 14.6 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Cyt-b5 PF00173.28 KUM59255.1 - 5.7e-20 71.2 0.0 8.2e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FMN_dh PF01070.18 KUM59255.1 - 0.047 12.7 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Cyclin_N PF00134.23 KUM59256.1 - 2.2e-05 24.2 0.0 0.0022 17.7 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 KUM59256.1 - 0.0015 18.5 0.0 0.05 13.7 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Hairy_orange PF07527.13 KUM59256.1 - 0.13 12.5 0.3 0.62 10.3 0.0 2.2 2 1 0 2 2 2 0 Hairy Orange zf-ribbon_3 PF13248.6 KUM59257.1 - 0.11 11.9 1.0 0.22 11.0 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain DUF728 PF05304.12 KUM59257.1 - 0.13 12.1 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF728) Zn_ribbon_recom PF13408.6 KUM59257.1 - 0.24 11.9 5.1 0.65 10.6 0.4 2.6 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Ogr_Delta PF04606.12 KUM59257.1 - 0.33 11.0 1.9 0.44 10.6 0.2 2.0 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DUF812 PF05667.11 KUM59258.1 - 0.028 13.3 6.8 0.037 12.9 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Exonuc_VII_L PF02601.15 KUM59258.1 - 0.039 13.5 7.2 0.056 13.0 7.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HAUS5 PF14817.6 KUM59258.1 - 0.05 12.4 9.5 0.069 11.9 9.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 ALMT PF11744.8 KUM59258.1 - 0.28 10.0 2.1 0.33 9.7 2.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Phage_GPO PF05929.11 KUM59258.1 - 0.46 10.1 8.2 0.65 9.6 8.2 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Tweety PF04906.13 KUM59258.1 - 0.57 8.8 2.5 0.79 8.3 2.5 1.1 1 0 0 1 1 1 0 Tweety DUF4407 PF14362.6 KUM59258.1 - 1.1 8.6 9.2 1.7 8.0 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2570 PF10828.8 KUM59258.1 - 1.1 9.1 7.9 0.1 12.4 2.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Ax_dynein_light PF10211.9 KUM59258.1 - 1.1 9.2 10.2 1.7 8.5 10.2 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Nup88 PF10168.9 KUM59258.1 - 2.5 5.8 10.1 3.8 5.2 10.1 1.2 1 0 0 1 1 1 0 Nuclear pore component AATF-Che1 PF13339.6 KUM59258.1 - 2.8 8.6 8.7 6.6 7.4 8.7 1.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Latarcin PF10279.9 KUM59258.1 - 8.9 6.8 13.7 47 4.5 13.7 2.1 1 1 0 1 1 1 0 Latarcin precursor Striatin PF08232.12 KUM59261.1 - 0.064 13.8 0.5 0.16 12.6 0.5 1.7 1 0 0 1 1 1 0 Striatin family Autophagy_N PF03986.13 KUM59262.1 - 3.6e-46 156.5 0.0 6.9e-46 155.6 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KUM59262.1 - 1.3e-15 56.5 0.5 2.4e-15 55.7 0.5 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KUM59262.1 - 2.4e-13 50.5 0.1 4.2e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Glycos_transf_2 PF00535.26 KUM59264.1 - 2.1e-23 82.9 0.0 1.8e-21 76.7 0.0 2.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KUM59264.1 - 3.1e-07 30.5 0.5 0.0038 17.1 0.1 2.8 1 1 0 2 2 2 2 Glycosyltransferase like family 2 Aldo_ket_red PF00248.21 KUM59265.1 - 2.1e-42 145.4 0.0 4.9e-40 137.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family P3A PF08727.11 KUM59265.1 - 0.042 13.2 0.1 0.86 9.0 0.1 2.8 3 0 0 3 3 3 0 Poliovirus 3A protein like Rit1_C PF17184.4 KUM59266.1 - 1.6e-74 250.8 0.0 1.7e-46 158.9 0.0 2.1 2 0 0 2 2 2 2 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KUM59266.1 - 1.7e-35 121.6 0.0 8.5e-35 119.4 0.0 2.0 2 0 0 2 2 2 1 Rit1 DUSP-like domain HAD_2 PF13419.6 KUM59267.1 - 5.5e-21 75.4 0.1 7.6e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KUM59267.1 - 2.2e-07 31.4 0.4 7.4e-07 29.7 0.4 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KUM59267.1 - 5.7e-06 26.3 0.1 1.3e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 KUM59267.1 - 0.0003 20.6 0.0 0.0086 15.9 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KUM59267.1 - 0.0012 19.3 0.0 0.0017 18.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sar8_2 PF03058.14 KUM59267.1 - 0.057 14.0 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 Sar8.2 family NUDIX PF00293.28 KUM59268.1 - 1.2e-18 67.4 0.0 1.9e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 KUM59269.1 - 2.1e-07 31.0 0.0 4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain EST1_DNA_bind PF10373.9 KUM59270.1 - 0.00014 21.5 0.2 0.00049 19.7 0.2 2.1 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain ALMS_motif PF15309.6 KUM59270.1 - 0.99 9.9 3.5 0.47 10.9 0.9 1.7 2 0 0 2 2 2 0 ALMS motif Creatinase_N PF01321.18 KUM59272.1 - 0.0045 17.7 0.0 0.0045 17.7 0.0 1.1 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Orn_Arg_deC_N PF02784.16 KUM59272.1 - 0.1 12.0 0.0 0.1 11.9 0.0 1.0 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain SOR_SNZ PF01680.17 KUM59273.1 - 2.5e-108 360.6 6.7 4e-108 359.9 6.7 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KUM59273.1 - 6.9e-09 35.4 7.3 2.7e-06 26.9 0.3 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG TetR_C_27 PF17935.1 KUM59273.1 - 9.4e-05 22.4 0.0 0.00055 20.0 0.0 2.1 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Dus PF01207.17 KUM59273.1 - 0.00022 20.4 0.4 0.15 11.1 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KUM59273.1 - 0.0023 17.4 0.5 0.14 11.6 0.0 3.0 2 2 1 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.21 KUM59273.1 - 0.0028 16.9 0.1 0.31 10.2 0.0 2.6 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 KUM59273.1 - 0.0078 15.4 1.0 0.17 11.1 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 KUM59273.1 - 0.045 13.1 7.2 0.061 12.7 0.3 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase OMPdecase PF00215.24 KUM59273.1 - 0.049 13.2 0.2 3.9 7.0 0.0 2.3 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family IBN_N PF03810.19 KUM59274.1 - 2.7e-06 27.2 1.5 7.2e-06 25.8 1.5 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Importin_rep_3 PF18806.1 KUM59274.1 - 0.0025 17.8 0.0 0.036 14.1 0.0 2.8 2 0 0 2 2 2 1 Importin 13 repeat Importin_rep PF18773.1 KUM59274.1 - 0.0081 15.8 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Importin 13 repeat Phage_Coat_Gp8 PF05371.12 KUM59274.1 - 0.11 12.3 2.4 0.98 9.2 0.2 2.8 2 0 0 2 2 2 0 Phage major coat protein, Gp8 ORC2 PF04084.14 KUM59275.1 - 3.2e-118 394.4 0.0 3.9e-118 394.2 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ORC6 PF05460.13 KUM59275.1 - 0.18 11.0 10.0 0.34 10.1 10.0 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FUN14 PF04930.15 KUM59276.1 - 4.7e-10 39.8 0.5 9.9e-10 38.7 0.5 1.5 1 0 0 1 1 1 1 FUN14 family DsbD PF02683.15 KUM59276.1 - 0.024 14.5 0.2 0.038 13.9 0.2 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region DUF543 PF04418.12 KUM59276.1 - 0.03 14.3 4.1 0.51 10.4 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) SecY PF00344.20 KUM59277.1 - 2.1e-72 244.0 7.9 2.6e-72 243.7 7.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KUM59277.1 - 7.4e-17 60.9 0.3 2e-16 59.5 0.3 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p MARVEL PF01284.23 KUM59277.1 - 0.64 10.0 0.0 0.64 10.0 0.0 3.1 2 1 0 2 2 2 0 Membrane-associating domain ArgJ PF01960.18 KUM59278.1 - 2.2e-151 503.8 0.8 2.6e-151 503.7 0.8 1.0 1 0 0 1 1 1 1 ArgJ family Abhydrolase_1 PF00561.20 KUM59279.1 - 2.8e-24 86.2 0.0 1.7e-23 83.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KUM59279.1 - 5.8e-19 68.1 0.0 1.4e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Med10 PF09748.9 KUM59279.1 - 0.21 11.6 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex ABC2_membrane PF01061.24 KUM59280.1 - 3.7e-36 124.5 17.1 6.4e-36 123.7 17.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KUM59280.1 - 1.4e-18 67.8 0.0 2.5e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 KUM59280.1 - 0.00041 20.0 0.0 0.00097 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KUM59280.1 - 0.0027 18.0 0.1 0.0074 16.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KUM59280.1 - 0.0052 16.7 0.2 0.011 15.7 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KUM59280.1 - 0.0075 16.7 0.1 0.014 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KUM59280.1 - 0.011 15.5 0.4 0.029 14.1 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain PDR_CDR PF06422.12 KUM59280.1 - 0.011 15.6 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 CDR ABC transporter AAA_21 PF13304.6 KUM59280.1 - 0.013 15.4 0.0 2.2 8.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KUM59280.1 - 0.076 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KUM59280.1 - 0.16 12.2 0.5 0.32 11.2 0.5 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KUM59280.1 - 0.19 11.2 0.1 2.2 7.7 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 KUM59280.1 - 0.86 8.6 17.8 0.03 13.4 11.7 1.6 1 1 0 2 2 2 0 ABC-2 family transporter protein ApbA PF02558.16 KUM59281.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1754 PF08555.10 KUM59282.1 - 1.8e-12 47.9 16.3 3e-12 47.2 16.3 1.4 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) CDT1 PF08839.11 KUM59282.1 - 0.1 12.9 1.1 0.12 12.6 1.1 1.1 1 0 0 1 1 1 0 DNA replication factor CDT1 like zf-AN1 PF01428.16 KUM59283.1 - 8.5e-13 48.2 5.7 8.5e-13 48.2 5.7 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KUM59283.1 - 0.018 15.4 4.2 0.018 15.4 4.2 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Tubulin PF00091.25 KUM59284.1 - 1.2e-68 231.2 0.0 2e-68 230.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KUM59284.1 - 2.8e-43 147.1 0.3 5.2e-43 146.2 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KUM59284.1 - 3.3e-08 33.9 0.0 6.9e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KUM59284.1 - 0.068 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Aldo_ket_red PF00248.21 KUM59286.1 - 7.8e-50 169.7 0.0 1.1e-49 169.3 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family EamA PF00892.20 KUM59286.1 - 4.4e-10 39.9 25.5 0.00011 22.3 1.2 2.5 2 0 0 2 2 2 2 EamA-like transporter family CSG2 PF16965.5 KUM59286.1 - 9e-05 21.6 10.5 0.00022 20.3 8.6 2.3 2 1 0 2 2 2 1 Ceramide synthase regulator DUF202 PF02656.15 KUM59286.1 - 0.065 13.7 0.4 0.065 13.7 0.4 4.2 5 1 0 5 5 5 0 Domain of unknown function (DUF202) Nuc_sug_transp PF04142.15 KUM59286.1 - 0.18 10.9 0.0 0.18 10.9 0.0 1.9 2 0 0 2 2 2 0 Nucleotide-sugar transporter Neurensin PF14927.6 KUM59286.1 - 0.29 10.8 1.3 4.8 6.9 0.1 2.9 2 1 0 2 2 2 0 Neurensin ABC2_membrane PF01061.24 KUM59288.1 - 7.2e-23 81.1 6.3 9.8e-23 80.7 6.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KUM59288.1 - 1.7e-16 61.0 0.0 3.3e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_trans_N PF14510.6 KUM59288.1 - 3.3e-09 37.2 0.0 7.6e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal Lantibiotic_a PF14867.6 KUM59288.1 - 0.24 11.2 0.5 0.44 10.3 0.5 1.4 1 0 0 1 1 1 0 Lantibiotic alpha ABC2_membrane PF01061.24 KUM59289.1 - 2.7e-15 56.4 4.8 3.5e-15 56.0 4.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 KUM59289.1 - 2.5e-10 40.1 0.0 2.5e-10 40.1 0.0 2.0 3 0 0 3 3 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 KUM59289.1 - 0.00025 20.3 0.9 0.00025 20.3 0.9 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DSPc PF00782.20 KUM59290.1 - 1.7e-13 50.5 0.4 2.8e-13 49.8 0.4 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KUM59290.1 - 0.003 17.9 0.0 0.0053 17.0 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain ArabFuran-catal PF09206.11 KUM59292.1 - 1.9e-150 500.5 10.2 1.9e-150 500.5 10.2 1.4 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 KUM59292.1 - 7.6e-55 184.7 2.4 1.2e-54 184.1 2.4 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain CBM_20 PF00686.19 KUM59293.1 - 5.9e-35 119.1 0.2 1.4e-34 117.9 0.2 1.7 1 0 0 1 1 1 1 Starch binding domain LPMO_10 PF03067.15 KUM59293.1 - 1.3e-05 25.9 8.9 4.4e-05 24.2 8.9 1.9 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Sporozoite_P67 PF05642.11 KUM59293.1 - 0.013 13.6 1.4 0.015 13.4 1.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AMPK1_CBM PF16561.5 KUM59293.1 - 0.013 15.7 0.2 0.075 13.3 0.0 2.2 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase Hamartin PF04388.12 KUM59293.1 - 0.3 9.7 2.3 0.39 9.3 2.3 1.1 1 0 0 1 1 1 0 Hamartin protein PTPA PF03095.15 KUM59294.1 - 2.6e-108 362.0 0.0 3.1e-108 361.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF202 PF02656.15 KUM59295.1 - 1.7e-22 79.6 0.5 1.7e-22 79.6 0.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Macoilin PF09726.9 KUM59295.1 - 2 6.8 8.2 2.7 6.5 8.2 1.2 1 0 0 1 1 1 0 Macoilin family CCDC158 PF15921.5 KUM59295.1 - 2.5 5.8 7.8 3.2 5.4 7.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 RSRP PF17069.5 KUM59295.1 - 2.5 7.6 16.5 4.4 6.8 16.5 1.4 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Actin PF00022.19 KUM59297.1 - 4.4e-111 371.4 0.0 2.7e-110 368.8 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KUM59297.1 - 0.0092 14.8 0.0 0.047 12.5 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein NAD_binding_2 PF03446.15 KUM59298.1 - 9.7e-28 97.3 0.1 1.5e-27 96.7 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KUM59298.1 - 5.6e-13 49.2 0.0 1.6e-12 47.7 0.0 1.8 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KUM59298.1 - 0.0013 19.2 0.0 0.0069 16.9 0.0 2.2 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent IMPDH PF00478.25 KUM59298.1 - 0.024 13.7 0.3 0.75 8.7 0.2 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Shikimate_DH PF01488.20 KUM59298.1 - 0.083 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Zemlya PF17646.1 KUM59298.1 - 0.17 12.3 0.2 0.4 11.1 0.1 1.6 2 0 0 2 2 2 0 Closterovirus 1a polyprotein central region Haspin_kinase PF12330.8 KUM59299.1 - 2.9 6.7 4.2 5.1 5.9 4.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Oxidored-like PF09791.9 KUM59300.1 - 3.4e-06 26.6 5.1 6.3e-06 25.8 5.1 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Mid1 PF12929.7 KUM59301.1 - 1.4e-157 525.2 4.8 1.8e-157 524.9 4.8 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KUM59301.1 - 0.0038 17.8 6.8 0.16 12.6 2.3 2.9 2 1 0 2 2 2 2 Fz domain Arabino_trans_N PF17689.1 KUM59302.1 - 0.041 14.0 0.0 0.82 9.8 0.0 2.0 1 1 1 2 2 2 0 Arabinosyltransferase concanavalin like domain SspB PF04386.13 KUM59302.1 - 0.075 12.9 0.0 0.084 12.8 0.0 1.1 1 0 0 1 1 1 0 Stringent starvation protein B Brix PF04427.18 KUM59303.1 - 1.2e-24 87.5 0.0 1.9e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.10 KUM59303.1 - 0.04 13.2 18.9 0.055 12.8 18.9 1.1 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 KUM59303.1 - 0.66 8.5 2.7 0.85 8.1 2.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HGTP_anticodon PF03129.20 KUM59304.1 - 4.9e-21 74.7 0.0 4.9e-21 74.7 0.0 2.8 3 1 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KUM59304.1 - 4e-08 33.4 0.0 2.5e-07 30.8 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Acyltransferase PF01553.21 KUM59305.1 - 1.6e-26 92.5 0.0 2.4e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KUM59305.1 - 5.3e-14 52.1 0.0 9.9e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus NAD_kinase PF01513.21 KUM59306.1 - 1.2e-49 169.1 0.0 1.8e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KUM59306.1 - 0.034 13.8 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain TPR_2 PF07719.17 KUM59308.1 - 2.7e-26 89.5 21.5 0.00031 20.6 0.4 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 KUM59308.1 - 2.4e-21 74.6 15.0 0.0021 17.8 0.0 9.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 KUM59308.1 - 2.9e-17 62.9 23.8 3.8e-06 27.3 0.1 8.6 9 1 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 KUM59308.1 - 2e-12 46.8 25.8 0.046 14.6 0.2 10.8 10 1 1 11 11 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KUM59308.1 - 1.6e-10 40.3 14.9 0.22 11.8 0.0 9.3 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 KUM59308.1 - 3.2e-07 29.9 11.9 0.8 9.4 0.0 7.4 7 1 1 8 8 8 2 TPR repeat TPR_7 PF13176.6 KUM59308.1 - 3.5e-07 29.8 17.4 0.0037 17.2 0.1 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KUM59308.1 - 2.3e-06 28.2 26.1 0.041 14.5 0.6 7.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KUM59308.1 - 2.6e-06 27.4 9.4 0.91 10.1 0.0 9.5 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_12 PF13424.6 KUM59308.1 - 1.7e-05 25.1 26.5 0.051 13.9 0.3 7.6 7 3 3 10 10 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 KUM59308.1 - 0.00023 21.6 27.6 0.034 14.8 0.1 10.9 14 0 0 14 14 12 2 Tetratricopeptide repeat TPR_4 PF07721.14 KUM59308.1 - 0.026 15.1 3.9 4.4 8.2 1.2 4.8 4 0 0 4 4 3 0 Tetratricopeptide repeat GGDEF_2 PF17853.1 KUM59308.1 - 0.029 14.6 0.1 0.19 12.0 0.0 2.5 2 0 0 2 2 2 0 GGDEF-like domain Fis1_TPR_C PF14853.6 KUM59308.1 - 0.34 11.0 3.7 12 6.0 0.1 4.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Es2 PF09751.9 KUM59309.1 - 1.4e-133 446.8 10.2 1.7e-133 446.5 10.2 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 APOC4 PF15119.6 KUM59309.1 - 0.022 15.0 0.1 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Apolipoprotein C4 adh_short PF00106.25 KUM59311.1 - 4.5e-34 117.6 0.0 5.5e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM59311.1 - 1.3e-26 93.6 0.0 1.6e-26 93.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM59311.1 - 5.9e-06 26.3 0.0 4.4e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 KR domain DUF3012 PF11216.8 KUM59311.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) Bacteriocin_IIi PF11758.8 KUM59313.1 - 0.0093 15.8 0.5 1.4 8.8 0.8 3.3 3 0 0 3 3 3 1 Aureocin-like type II bacteriocin DUF2242 PF10001.9 KUM59313.1 - 0.15 12.2 0.3 0.26 11.5 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2242) TTL PF03133.15 KUM59314.1 - 0.0052 16.0 0.0 0.0068 15.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 KUM59314.1 - 0.057 12.7 0.0 0.1 11.8 0.0 1.4 1 1 0 1 1 1 0 Sugar-transfer associated ATP-grasp Pkinase PF00069.25 KUM59316.1 - 4.3e-66 223.0 3.3 7.8e-66 222.1 0.6 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM59316.1 - 3.2e-50 170.8 0.0 6.2e-50 169.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KUM59316.1 - 1.2e-24 86.4 0.3 6.5e-24 84.1 0.0 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.6 KUM59316.1 - 2.2e-11 44.1 0.1 5.6e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 KUM59316.1 - 9.6e-06 25.1 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KUM59316.1 - 0.00011 21.1 0.0 0.00011 21.1 0.0 1.9 3 0 0 3 3 3 1 Fungal protein kinase PH PF00169.29 KUM59316.1 - 0.00016 22.1 0.1 0.00042 20.8 0.1 1.7 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 KUM59316.1 - 0.0043 16.1 0.1 0.0083 15.1 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KUM59316.1 - 0.014 15.4 0.3 0.046 13.6 0.4 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KUM59316.1 - 0.047 12.7 0.1 0.08 12.0 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DNA_pol_E_B PF04042.16 KUM59317.1 - 1e-48 165.5 0.0 1.4e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Med14 PF08638.11 KUM59318.1 - 3.9e-66 222.1 0.0 5.9e-66 221.5 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 ATG22 PF11700.8 KUM59320.1 - 4.2e-212 705.0 12.2 4.8e-212 704.8 12.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KUM59320.1 - 7e-08 31.8 19.6 7e-08 31.8 19.6 3.2 2 1 0 3 3 3 2 Major Facilitator Superfamily ODC_AZ PF02100.17 KUM59321.1 - 3.3e-40 136.6 0.1 3.8e-40 136.4 0.1 1.0 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Yippee-Mis18 PF03226.14 KUM59323.1 - 6.3e-24 84.2 0.1 9.1e-24 83.7 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KUM59323.1 - 0.072 13.3 0.7 1.4 9.2 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I DUF678 PF05077.12 KUM59323.1 - 0.11 12.7 0.2 3 8.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Transp_Tc5_C PF04236.15 KUM59323.1 - 0.14 12.5 2.4 2 8.9 0.2 2.8 3 1 0 3 3 3 0 Tc5 transposase C-terminal domain SHNi-TPR PF10516.9 KUM59324.1 - 3.3e-14 52.0 0.3 1.1e-13 50.4 0.3 1.9 1 0 0 1 1 1 1 SHNi-TPR TPR_12 PF13424.6 KUM59324.1 - 0.00058 20.1 8.0 0.19 12.0 1.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KUM59324.1 - 0.007 16.0 2.6 6.3 6.6 0.2 4.0 4 0 0 4 4 4 1 TPR repeat BTAD PF03704.17 KUM59324.1 - 0.031 14.7 0.7 0.031 14.7 0.7 2.4 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 KUM59324.1 - 0.06 13.5 0.8 2.9 8.1 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2746 PF10874.8 KUM59324.1 - 0.15 12.5 0.7 0.56 10.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) Snapin_Pallidin PF14712.6 KUM59324.1 - 1 9.8 5.6 4 7.9 1.0 3.1 3 0 0 3 3 3 0 Snapin/Pallidin CCDC-167 PF15188.6 KUM59324.1 - 2.8 8.3 11.4 0.042 14.2 2.7 2.4 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 TPR_14 PF13428.6 KUM59324.1 - 5.9 8.0 5.5 14 6.8 0.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KUM59324.1 - 8.3 6.8 0.0 8.3 6.8 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Thioredoxin PF00085.20 KUM59325.1 - 5.9e-64 212.5 3.1 4.5e-32 110.1 0.1 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KUM59325.1 - 2.9e-46 157.7 5.9 3.1e-35 121.8 0.5 3.4 3 1 1 4 4 4 3 Thioredoxin-like domain Calsequestrin PF01216.17 KUM59325.1 - 1e-10 41.3 0.9 1e-10 41.3 0.9 1.9 2 1 0 2 2 2 1 Calsequestrin Redoxin PF08534.10 KUM59325.1 - 2.8e-09 36.8 2.7 0.013 15.2 0.1 3.5 3 0 0 3 3 3 3 Redoxin Thioredoxin_2 PF13098.6 KUM59325.1 - 1.3e-08 35.3 1.1 0.0077 16.7 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KUM59325.1 - 4.6e-08 33.1 0.2 0.01 16.0 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KUM59325.1 - 5.1e-08 32.9 2.1 0.00024 21.0 0.0 3.4 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_8 PF13905.6 KUM59325.1 - 1.5e-07 31.6 0.1 0.041 14.2 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like ERp29_N PF07912.13 KUM59325.1 - 2.1e-05 24.7 0.2 0.29 11.3 0.0 4.0 4 0 0 4 4 4 2 ERp29, N-terminal domain OST3_OST6 PF04756.13 KUM59325.1 - 4.4e-05 23.0 0.0 0.36 10.2 0.0 3.3 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 KUM59325.1 - 3.9 7.6 6.9 10 6.3 0.1 3.3 4 0 0 4 4 4 0 Thioredoxin UDG PF03167.19 KUM59326.1 - 1.9e-24 86.4 0.1 3.7e-24 85.5 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily MFS_1 PF07690.16 KUM59327.1 - 1.2e-31 110.0 19.9 1.2e-31 110.0 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM59327.1 - 2.7e-09 36.4 3.5 2.7e-09 36.4 3.5 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KUM59327.1 - 0.00026 20.0 2.4 0.00026 20.0 2.4 2.3 2 0 0 2 2 2 1 MFS_1 like family MFS_3 PF05977.13 KUM59327.1 - 0.004 15.6 4.8 0.17 10.3 2.9 2.5 1 1 1 2 2 2 2 Transmembrane secretion effector DWNN PF08783.11 KUM59328.1 - 2.2e-33 114.4 0.8 4.7e-33 113.3 0.1 1.9 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 KUM59328.1 - 3.6e-08 33.1 5.0 6.5e-08 32.3 5.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KUM59328.1 - 0.002 18.1 0.7 0.0041 17.1 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 KUM59328.1 - 0.0024 17.7 8.2 0.005 16.7 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KUM59328.1 - 0.27 11.1 3.4 0.61 10.0 3.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 KUM59328.1 - 0.32 11.4 6.6 0.69 10.3 6.6 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 KUM59328.1 - 0.4 10.5 6.0 0.97 9.3 6.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain THOC2_N PF16134.5 KUM59328.1 - 0.85 8.2 3.9 1.4 7.5 3.9 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus zf-C3HC4 PF00097.25 KUM59328.1 - 3.5 7.6 8.2 7.8 6.5 8.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KUM59328.1 - 4 7.7 9.3 11 6.3 9.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KUM59328.1 - 7.9 6.5 11.6 0.48 10.4 5.4 2.1 2 0 0 2 2 2 0 zinc-RING finger domain His_biosynth PF00977.21 KUM59329.1 - 3.6e-45 154.2 0.4 8.5e-45 153.0 0.4 1.6 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KUM59329.1 - 1.7e-23 83.4 0.0 2.9e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KUM59329.1 - 1.8e-10 41.0 0.0 1.6e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KUM59329.1 - 2.3e-09 37.2 0.0 4.2e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KUM59329.1 - 0.0055 16.5 0.1 0.053 13.3 0.1 2.2 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KUM59329.1 - 0.05 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family dCMP_cyt_deam_1 PF00383.23 KUM59330.1 - 5.1e-28 96.9 0.9 7.4e-28 96.4 0.9 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KUM59330.1 - 7.4e-12 45.2 0.1 1.3e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase ThiF PF00899.21 KUM59331.1 - 2.1e-43 148.5 0.0 3.1e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family ATG7_N PF16420.5 KUM59331.1 - 9.9e-38 130.5 0.1 1.3e-37 130.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Shikimate_DH PF01488.20 KUM59331.1 - 0.0059 16.7 0.0 0.21 11.7 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KUM59331.1 - 0.16 11.3 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FtsJ PF01728.19 KUM59332.1 - 5.7e-55 186.1 0.0 7.1e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KUM59332.1 - 7.8e-05 22.6 0.0 0.00013 21.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM59332.1 - 0.0015 18.4 0.0 0.25 11.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KUM59332.1 - 0.0049 17.6 0.0 0.21 12.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_S49_N PF08496.10 KUM59333.1 - 2.1 8.4 10.0 1.4 9.0 5.7 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Fungal_trans PF04082.18 KUM59334.1 - 7.3e-31 107.2 1.2 1.1e-30 106.5 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM59334.1 - 0.00094 19.3 17.6 0.0017 18.5 17.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM59335.1 - 2.6e-09 36.5 0.0 3.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_TACC PF12709.7 KUM59336.1 - 6.5e-11 42.5 16.8 4.2e-09 36.7 2.9 4.4 4 0 0 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins RasGAP_C PF03836.15 KUM59336.1 - 0.22 11.7 4.8 0.62 10.2 4.8 1.8 1 0 0 1 1 1 0 RasGAP C-terminus Herpes_UL6 PF01763.16 KUM59336.1 - 0.42 9.1 12.3 0.33 9.4 5.6 2.4 1 1 1 2 2 2 0 Herpesvirus UL6 like Filament PF00038.21 KUM59336.1 - 0.63 9.6 32.7 5.8 6.4 14.8 3.0 1 1 1 2 2 2 0 Intermediate filament protein QueH PF02677.14 KUM59336.1 - 1.9 8.6 5.9 3.5 7.7 5.9 1.4 1 0 0 1 1 1 0 Epoxyqueuosine reductase QueH TolA_bind_tri PF16331.5 KUM59336.1 - 3.9 7.6 7.6 0.22 11.6 0.4 2.7 3 0 0 3 3 3 0 TolA binding protein trimerisation Tropomyosin_1 PF12718.7 KUM59336.1 - 8.2 6.6 37.7 0.52 10.5 24.1 3.5 2 1 1 3 3 3 0 Tropomyosin like Dyp_perox PF04261.12 KUM59337.1 - 2.3e-09 36.7 0.0 2.1e-07 30.2 0.0 2.9 3 0 0 3 3 3 2 Dyp-type peroxidase family PD40 PF07676.12 KUM59337.1 - 0.1 12.6 0.1 1.6 8.8 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF2347 PF09804.9 KUM59338.1 - 3.2e-103 345.2 0.0 4.4e-103 344.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KUM59338.1 - 2.4e-59 200.9 0.4 3.6e-59 200.3 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.9 KUM59338.1 - 0.0023 16.7 0.0 2 7.0 0.0 2.5 2 1 0 3 3 3 2 Transport protein Avl9 SPA PF08616.10 KUM59338.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 1 0 1 1 1 0 Stabilization of polarity axis CorA PF01544.18 KUM59339.1 - 7.2 5.8 6.3 11 5.3 5.4 1.7 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Tubulin_3 PF14881.6 KUM59340.1 - 1.4e-59 200.8 0.0 2.4e-59 200.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain adh_short_C2 PF13561.6 KUM59342.1 - 7e-48 163.2 6.0 8.2e-48 163.0 6.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM59342.1 - 3.6e-39 134.2 0.6 4.6e-39 133.9 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM59342.1 - 1.4e-11 44.6 1.7 2.3e-11 43.9 1.7 1.3 1 0 0 1 1 1 1 KR domain AA_permease PF00324.21 KUM59343.1 - 2.7e-47 161.4 7.8 3e-47 161.3 7.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM59343.1 - 2e-10 40.1 11.1 2.7e-10 39.7 11.1 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1929 PF09118.11 KUM59344.1 - 1.3e-21 76.6 0.0 2.7e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.25 KUM59344.1 - 2.1e-17 63.4 0.2 5.8e-17 62.0 0.2 1.8 1 0 0 1 1 1 1 F5/8 type C domain Kelch_1 PF01344.25 KUM59344.1 - 2.5e-15 55.7 0.3 4.4e-07 29.4 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 KUM59344.1 - 4.4e-15 55.3 1.9 1.6e-06 28.2 0.0 4.8 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KUM59344.1 - 8.1e-12 45.0 1.4 0.0003 20.7 0.0 4.1 3 1 0 3 3 3 2 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.11 KUM59344.1 - 6.1e-08 32.2 0.4 0.00053 19.3 0.1 3.0 2 1 1 3 3 3 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.15 KUM59344.1 - 5.3e-07 29.4 0.5 0.13 12.3 0.0 4.6 4 1 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 KUM59344.1 - 4.6e-06 26.8 1.7 0.88 9.9 0.0 5.3 4 1 0 4 4 4 2 Galactose oxidase, central domain SWIM PF04434.17 KUM59344.1 - 0.094 12.4 0.2 0.17 11.5 0.2 1.5 1 0 0 1 1 1 0 SWIM zinc finger p450 PF00067.22 KUM59345.1 - 6.3e-39 134.0 0.0 8.2e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UAA PF08449.11 KUM59345.1 - 0.097 11.9 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 UAA transporter family NACHT PF05729.12 KUM59347.1 - 8.4e-09 35.5 0.0 2.1e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NACHT_N PF17100.5 KUM59347.1 - 5.4e-07 29.7 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 KUM59347.1 - 6.2e-05 23.5 5.6 0.3 11.7 0.1 5.8 7 0 0 7 7 7 1 Ankyrin repeats (3 copies) AAA_22 PF13401.6 KUM59347.1 - 0.0023 18.2 0.0 0.01 16.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KUM59347.1 - 0.043 14.2 1.0 0.21 11.9 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA PF00004.29 KUM59347.1 - 0.092 13.2 0.1 0.88 10.0 0.1 2.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KUM59347.1 - 0.097 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain DUF4201 PF13870.6 KUM59347.1 - 0.12 12.1 0.9 0.27 11.0 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) RNA_helicase PF00910.22 KUM59347.1 - 0.19 12.1 0.0 0.53 10.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase adh_short_C2 PF13561.6 KUM59348.1 - 1.6e-63 214.4 0.4 1.9e-63 214.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM59348.1 - 9.1e-53 178.6 2.0 1.1e-52 178.3 2.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM59348.1 - 1.2e-12 48.2 0.4 2e-12 47.4 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM59348.1 - 0.00044 19.8 0.5 0.0011 18.5 0.5 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KUM59348.1 - 0.0014 18.5 2.0 0.0023 17.8 2.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KUM59348.1 - 0.0027 17.0 1.0 0.0043 16.4 1.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KUM59348.1 - 0.029 14.5 0.8 0.086 13.0 0.8 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase THF_DHG_CYH_C PF02882.19 KUM59348.1 - 0.036 13.4 0.3 0.081 12.2 0.2 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.21 KUM59348.1 - 0.042 13.9 0.5 0.32 11.0 0.2 2.4 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3Beta_HSD PF01073.19 KUM59348.1 - 0.051 12.6 0.0 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KUM59348.1 - 0.067 12.6 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RNA_pol_Rpb1_4 PF05000.17 KUM59348.1 - 0.16 12.0 0.9 0.28 11.1 0.9 1.5 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 4 Sugar_tr PF00083.24 KUM59349.1 - 3.8e-71 240.3 32.6 4.8e-71 240.0 32.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM59349.1 - 3.7e-30 105.0 31.0 3.7e-30 105.0 31.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3593 PF12159.8 KUM59349.1 - 0.21 11.7 5.1 0.11 12.6 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) adh_short_C2 PF13561.6 KUM59351.1 - 5.4e-42 143.9 0.8 6.9e-38 130.5 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM59351.1 - 1.3e-41 142.3 0.2 1.6e-41 141.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM59351.1 - 3.2e-17 63.0 0.0 4.6e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM59351.1 - 2.8e-06 27.0 0.0 1.1e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KUM59351.1 - 0.00046 19.4 0.1 0.00086 18.5 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KUM59351.1 - 0.0067 15.9 0.0 0.014 14.8 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Dak1_2 PF13684.6 KUM59351.1 - 0.046 12.8 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family RmlD_sub_bind PF04321.17 KUM59351.1 - 0.048 12.7 0.1 0.086 11.9 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Spore_IV_A PF09547.10 KUM59351.1 - 0.099 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) HSP70 PF00012.20 KUM59354.1 - 8e-68 229.1 5.5 3.4e-66 223.7 5.5 2.5 1 1 0 1 1 1 1 Hsp70 protein NACHT_N PF17100.5 KUM59354.1 - 9.5 6.0 7.2 0.88 9.4 0.4 2.5 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase XPA_C PF05181.12 KUM59356.1 - 1.6e-20 72.8 6.1 1.3e-12 47.5 0.3 2.6 2 0 0 2 2 2 2 XPA protein C-terminus YhfH PF14149.6 KUM59356.1 - 0.026 14.5 5.3 0.72 9.9 0.7 2.7 2 0 0 2 2 2 0 YhfH-like protein XPA_N PF01286.18 KUM59356.1 - 8.1 6.6 15.0 1.1 9.4 8.3 2.3 2 0 0 2 2 2 0 XPA protein N-terminal ArfGap PF01412.18 KUM59356.1 - 8.1 6.5 11.6 0.14 12.2 2.9 2.5 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf PIG-P PF08510.12 KUM59357.1 - 2.1e-47 160.0 6.1 6.8e-44 148.7 0.5 2.4 2 0 0 2 2 2 2 PIG-P adh_short_C2 PF13561.6 KUM59358.1 - 2.2e-62 210.7 1.2 2.7e-62 210.4 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM59358.1 - 1.8e-52 177.6 1.1 2.4e-52 177.3 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM59358.1 - 2.4e-10 40.6 0.1 3.9e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 KR domain FNIP_C PF14638.6 KUM59358.1 - 0.0037 16.9 0.2 0.0058 16.3 0.2 1.2 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus Eno-Rase_NADH_b PF12242.8 KUM59358.1 - 0.039 13.7 0.9 0.094 12.5 0.9 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AdoHcyase_NAD PF00670.21 KUM59358.1 - 0.047 13.8 3.0 0.12 12.4 3.0 1.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GDP_Man_Dehyd PF16363.5 KUM59358.1 - 0.048 13.1 0.2 0.56 9.6 0.1 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Peripla_BP_6 PF13458.6 KUM59358.1 - 0.051 13.2 0.1 0.074 12.7 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein HAD_2 PF13419.6 KUM59359.1 - 9.6e-10 38.8 0.0 1.1e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KUM59359.1 - 0.00024 21.5 0.0 0.00042 20.7 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KUM59359.1 - 0.0095 16.0 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2608 PF11019.8 KUM59359.1 - 0.2 11.1 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) HAD_2 PF13419.6 KUM59360.1 - 3.1e-06 27.4 0.0 5.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KUM59360.1 - 0.021 15.1 0.0 0.07 13.4 0.0 1.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase DUF503 PF04456.12 KUM59360.1 - 0.06 13.2 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF503) p450 PF00067.22 KUM59361.1 - 1.6e-71 241.4 0.0 2.1e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1707 PF08044.11 KUM59361.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) AMP-binding PF00501.28 KUM59362.1 - 2.4e-73 247.1 0.0 3.2e-73 246.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KUM59362.1 - 8.4e-16 57.7 0.0 2.6e-13 49.4 0.1 2.4 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KUM59362.1 - 2.8e-09 37.2 0.0 1.3e-07 31.9 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site p450 PF00067.22 KUM59363.1 - 8.7e-68 229.1 0.0 1.1e-67 228.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 4HBT PF03061.22 KUM59364.1 - 1e-12 48.2 1.3 1.8e-12 47.4 1.3 1.4 1 0 0 1 1 1 1 Thioesterase superfamily BATS PF06968.13 KUM59364.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.4 1 1 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain YdjM PF04307.14 KUM59364.1 - 0.018 14.4 0.5 0.023 14.0 0.5 1.2 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase DUF4442 PF14539.6 KUM59364.1 - 0.049 13.8 0.0 0.061 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) adh_short_C2 PF13561.6 KUM59365.1 - 1.1e-60 205.1 1.5 1.4e-60 204.8 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM59365.1 - 8.2e-48 162.5 2.0 9.7e-48 162.2 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM59365.1 - 4.8e-05 23.3 0.3 7.4e-05 22.7 0.3 1.2 1 0 0 1 1 1 1 KR domain HAD_2 PF13419.6 KUM59366.1 - 3.5e-10 40.3 0.0 4e-10 40.1 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KUM59366.1 - 5.3e-05 23.6 0.0 0.00034 21.0 0.0 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KUM59366.1 - 0.00035 20.6 0.0 0.00059 19.9 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2608 PF11019.8 KUM59366.1 - 0.036 13.6 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) p450 PF00067.22 KUM59367.1 - 2.6e-70 237.4 0.0 3.2e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DS PF01916.17 KUM59368.1 - 6e-127 422.8 0.0 6.9e-127 422.6 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Carbam_trans_N PF02543.15 KUM59368.1 - 0.14 11.8 0.1 0.22 11.2 0.1 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus MAGE_N PF12440.8 KUM59369.1 - 0.18 12.5 1.0 0.3 11.8 1.0 1.3 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Striatin PF08232.12 KUM59370.1 - 5.8e-42 143.9 7.2 5.8e-42 143.9 7.2 2.3 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 KUM59370.1 - 2.4e-24 85.1 19.2 0.00044 21.0 0.0 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM59370.1 - 0.00065 19.9 0.1 20 5.6 0.0 4.4 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain CENP-Q PF13094.6 KUM59370.1 - 0.0078 16.4 7.0 0.0078 16.4 7.0 1.9 3 0 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit eIF2A PF08662.11 KUM59370.1 - 0.049 13.5 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A ADH_N_2 PF16884.5 KUM59370.1 - 0.053 13.4 0.0 3 7.8 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Ge1_WD40 PF16529.5 KUM59370.1 - 0.2 10.6 0.0 0.68 8.8 0.0 1.9 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Blt1 PF12754.7 KUM59371.1 - 2.6e-69 232.3 0.1 3.3e-69 232.0 0.1 1.1 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 KUM59371.1 - 1.3e-25 88.8 0.1 2.6e-25 87.7 0.1 1.6 1 0 0 1 1 1 1 Get5 carboxyl domain DUF5044 PF16447.5 KUM59371.1 - 0.15 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5044) Methyltr_RsmB-F PF01189.17 KUM59372.1 - 7.4e-72 241.2 0.0 1.3e-71 240.4 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KUM59372.1 - 8.5e-08 32.6 0.0 3e-07 30.8 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 KUM59372.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 KUM59372.1 - 0.035 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MORN PF02493.20 KUM59373.1 - 1.9e-14 52.6 22.6 3.6e-05 23.4 0.7 4.7 4 0 0 4 4 4 4 MORN repeat zf-C3HC4_3 PF13920.6 KUM59373.1 - 1.5e-10 40.7 10.7 2.5e-10 40.1 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.29 KUM59373.1 - 4.9e-10 39.3 0.0 8.1e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KUM59373.1 - 0.00047 20.3 0.1 1.8 8.8 0.0 2.8 3 0 0 3 3 3 2 MATH domain Prok-RING_4 PF14447.6 KUM59373.1 - 0.0013 18.5 10.5 0.0025 17.6 10.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 UCH_1 PF13423.6 KUM59373.1 - 0.068 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase zf-RING_5 PF14634.6 KUM59373.1 - 1.5 8.8 11.7 2.8 8.0 11.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain SMI1_KNR4 PF09346.10 KUM59374.1 - 0.0027 18.1 0.0 0.0048 17.3 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Desmo_N PF06771.11 KUM59374.1 - 0.086 13.2 0.0 15 6.0 0.1 2.3 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus hEGF PF12661.7 KUM59374.1 - 0.11 13.1 0.6 0.24 12.1 0.6 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF PAD_porph PF04371.15 KUM59375.1 - 6.8e-98 327.9 0.0 7.9e-98 327.7 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase CysA_C_terminal PF17850.1 KUM59375.1 - 0.02 15.4 0.4 0.26 11.9 0.0 2.5 2 0 0 2 2 2 0 CysA C-terminal regulatory domain Orn_Arg_deC_N PF02784.16 KUM59376.1 - 6.4e-61 205.9 0.0 8.1e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KUM59376.1 - 1.9e-16 60.1 0.0 2.7e-16 59.6 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 KUM59376.1 - 0.00015 21.5 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Opi1 PF08618.10 KUM59377.1 - 2e-46 159.1 10.6 8.9e-33 114.1 1.9 3.1 1 1 2 3 3 3 3 Transcription factor Opi1 DUF4726 PF15855.5 KUM59377.1 - 0.025 14.8 0.0 0.095 12.9 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) RdRP PF05183.12 KUM59378.1 - 2.1e-132 442.8 0.0 3.2e-132 442.1 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase WXG100 PF06013.12 KUM59378.1 - 0.055 13.7 2.9 0.13 12.6 2.9 1.5 1 0 0 1 1 1 0 Proteins of 100 residues with WXG NmrA PF05368.13 KUM59379.1 - 1.4e-26 93.5 0.0 1.8e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM59379.1 - 1.9e-15 57.2 0.0 2.7e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KUM59379.1 - 1.9e-06 28.1 0.1 3.2e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KUM59379.1 - 0.0026 18.2 0.0 0.0044 17.5 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KUM59379.1 - 0.0042 17.0 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM59379.1 - 0.0063 16.0 0.0 0.03 13.8 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2985 PF11204.8 KUM59380.1 - 1.2e-22 79.9 2.3 2.4e-22 78.9 2.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) GvpK PF05121.12 KUM59380.1 - 0.55 10.3 3.4 1.2 9.2 3.4 1.5 1 0 0 1 1 1 0 Gas vesicle protein K Hydrophobin PF01185.18 KUM59381.1 - 9.3e-10 39.0 6.6 1.3e-09 38.6 6.6 1.2 1 0 0 1 1 1 1 Fungal hydrophobin MFS_1 PF07690.16 KUM59382.1 - 2.4e-41 141.9 30.9 4.8e-38 131.0 21.7 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KUM59382.1 - 1.7e-05 23.6 19.1 0.0014 17.3 2.0 3.0 2 2 0 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 KUM59382.1 - 0.00032 19.1 11.8 0.035 12.4 5.7 2.8 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KUM59382.1 - 0.00052 19.0 6.6 0.00052 19.0 6.6 2.8 2 1 0 2 2 2 2 MFS_1 like family AA_permease PF00324.21 KUM59383.1 - 1.2e-75 254.9 35.8 1.5e-75 254.6 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM59383.1 - 8e-15 54.6 37.4 1e-14 54.2 37.4 1.2 1 0 0 1 1 1 1 Amino acid permease TMEM138 PF14935.6 KUM59383.1 - 0.052 14.2 3.2 0.07 13.8 0.2 2.7 2 0 0 2 2 2 0 Transmembrane protein 138 Stevor PF17410.2 KUM59383.1 - 5.5 6.4 7.9 0.25 10.8 2.0 1.7 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame ArfGap PF01412.18 KUM59384.1 - 3.6e-30 104.4 0.1 7.1e-30 103.5 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GTP_EFTU PF00009.27 KUM59385.1 - 2.1e-54 184.1 0.0 3.1e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KUM59385.1 - 8.9e-26 89.8 0.0 1.9e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KUM59385.1 - 2.8e-16 59.3 0.1 3.2e-09 36.7 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KUM59385.1 - 2.8e-06 27.6 0.0 6.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KUM59385.1 - 0.0023 17.8 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain DUF2383 PF09537.10 KUM59385.1 - 0.078 13.3 0.1 0.22 11.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) EFG_IV PF03764.18 KUM59385.1 - 0.11 12.3 0.1 0.65 9.8 0.0 2.3 1 1 1 2 2 2 0 Elongation factor G, domain IV DUF2095 PF09868.9 KUM59385.1 - 0.19 11.7 0.5 0.51 10.3 0.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) HypD PF01924.16 KUM59385.1 - 0.2 10.7 0.1 0.48 9.4 0.1 1.5 2 0 0 2 2 2 0 Hydrogenase formation hypA family Epimerase PF01370.21 KUM59387.1 - 4.6e-09 36.1 0.1 0.00064 19.2 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KUM59387.1 - 2.4e-05 24.0 0.0 3.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM59387.1 - 3.2e-05 23.9 0.0 4.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KUM59387.1 - 4.6e-05 23.8 0.0 8.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KUM59387.1 - 0.094 11.7 0.0 1.3 8.0 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family TMV_coat PF00721.21 KUM59387.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Virus coat protein (TMV like) THOC2_N PF16134.5 KUM59388.1 - 4.4e-245 815.2 0.0 9.8e-245 814.0 0.0 1.6 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KUM59388.1 - 1.4e-105 352.8 0.0 2.2e-105 352.1 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KUM59388.1 - 3e-30 104.1 0.1 1.3e-29 102.0 0.0 2.1 2 0 0 2 2 2 1 Transcription- and export-related complex subunit SAPS PF04499.15 KUM59388.1 - 0.14 10.9 0.9 0.38 9.5 0.8 1.8 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein Vps5 PF09325.10 KUM59389.1 - 1.5e-14 54.1 0.6 2.5e-14 53.4 0.6 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KUM59389.1 - 4.6e-10 39.5 0.0 9.5e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 PX domain KAsynt_C_assoc PF16197.5 KUM59389.1 - 0.14 12.7 0.6 0.31 11.5 0.6 1.5 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension GFA PF04828.14 KUM59390.1 - 5.9e-17 61.8 0.1 8.7e-17 61.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 KUM59390.1 - 0.22 11.7 3.5 0.47 10.6 3.5 1.7 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like RRM_1 PF00076.22 KUM59392.1 - 6.6e-32 109.1 0.3 7.7e-15 54.5 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KUM59392.1 - 1.7e-05 24.9 0.0 0.018 15.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 KUM59392.1 - 0.0016 18.0 0.0 1.5 8.5 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KUM59392.1 - 0.0071 16.6 1.8 2.5 8.3 0.2 3.2 2 2 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 KUM59392.1 - 0.036 13.9 0.0 0.32 10.8 0.0 2.3 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 KUM59392.1 - 0.12 12.3 0.1 10 6.0 0.0 3.0 3 0 0 3 3 3 0 Occluded RNA-recognition motif FXMRP1_C_core PF12235.8 KUM59392.1 - 0.27 11.9 11.3 0.61 10.7 11.3 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal DNA_ligase_IV PF11411.8 KUM59392.1 - 0.31 11.2 1.0 24 5.2 0.1 2.4 2 0 0 2 2 2 0 DNA ligase IV Inp1 PF12634.7 KUM59393.1 - 3.7e-40 137.1 0.0 8e-40 136.0 0.0 1.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 SRP14 PF02290.15 KUM59394.1 - 1.2e-26 92.9 0.1 1.8e-26 92.3 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein FmdA_AmdA PF03069.15 KUM59395.1 - 4.8e-180 598.3 0.0 5.4e-180 598.1 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family EI24 PF07264.11 KUM59396.1 - 4.9e-12 46.4 5.3 5.3e-05 23.5 2.4 2.4 1 1 1 2 2 2 2 Etoposide-induced protein 2.4 (EI24) Mannosyl_trans PF05007.13 KUM59396.1 - 0.00051 20.0 0.4 0.0011 18.9 0.4 1.5 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) ApoLp-III PF07464.11 KUM59397.1 - 0.00042 20.4 2.1 0.00042 20.4 2.1 1.8 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Bacillus_HBL PF05791.11 KUM59397.1 - 0.00079 19.3 2.3 0.004 17.0 2.3 1.9 1 1 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) DUF2205 PF10224.9 KUM59397.1 - 0.0011 18.9 4.9 0.055 13.5 2.1 2.8 1 1 1 2 2 2 1 Short coiled-coil protein DHC_N1 PF08385.12 KUM59397.1 - 0.0054 15.4 1.5 0.13 10.9 0.0 2.1 1 1 1 2 2 2 1 Dynein heavy chain, N-terminal region 1 DUF4071 PF13281.6 KUM59397.1 - 0.0081 15.3 2.3 0.015 14.4 2.3 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4071) DUF5082 PF16888.5 KUM59397.1 - 0.0086 16.3 9.2 7.5 6.8 3.6 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) RPW8 PF05659.11 KUM59397.1 - 0.0097 15.6 4.1 0.019 14.7 4.1 1.4 1 1 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 GrpE PF01025.19 KUM59397.1 - 0.015 14.9 3.3 0.031 14.0 3.3 1.5 1 1 0 1 1 1 0 GrpE Filament PF00038.21 KUM59397.1 - 0.017 14.7 1.8 0.017 14.7 1.8 1.8 1 1 0 2 2 2 0 Intermediate filament protein GARP PF16731.5 KUM59397.1 - 0.02 14.6 0.1 0.041 13.6 0.1 1.5 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma Helo_like_N PF17111.5 KUM59397.1 - 0.022 14.1 4.7 2 7.7 0.8 2.5 1 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Uso1_p115_C PF04871.13 KUM59397.1 - 0.023 15.0 3.7 0.023 15.0 3.7 1.7 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region V-SNARE_C PF12352.8 KUM59397.1 - 0.027 14.8 2.5 5.1 7.5 0.1 3.0 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.11 KUM59397.1 - 0.029 12.3 2.3 0.043 11.8 2.3 1.2 1 0 0 1 1 1 0 Prominin CEP63 PF17045.5 KUM59397.1 - 0.034 14.1 6.6 0.064 13.2 6.4 1.4 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa SesA PF17107.5 KUM59397.1 - 0.042 14.0 0.6 4.3 7.5 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Tho2 PF11262.8 KUM59397.1 - 0.042 13.0 2.2 0.047 12.9 1.3 1.4 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Baculo_PEP_C PF04513.12 KUM59397.1 - 0.064 13.3 1.0 0.16 12.0 0.9 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.11 KUM59397.1 - 0.081 12.3 3.4 0.15 11.4 0.4 2.2 1 1 0 2 2 2 0 SF-assemblin/beta giardin UCH PF00443.29 KUM59397.1 - 0.11 12.0 0.8 0.14 11.6 0.8 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Med9 PF07544.13 KUM59397.1 - 0.11 12.6 3.1 0.2 11.8 0.4 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Cnn_1N PF07989.11 KUM59397.1 - 0.16 12.2 2.8 0.21 11.8 0.4 2.2 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF1664 PF07889.12 KUM59397.1 - 0.17 11.9 5.0 2.5 8.1 2.1 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 KUM59397.1 - 0.19 10.8 3.4 0.24 10.4 3.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 COG2 PF06148.11 KUM59397.1 - 0.2 11.8 3.5 0.65 10.1 0.3 2.7 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 KUM59397.1 - 0.21 11.8 2.9 3.5 8.0 2.9 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) YlbD_coat PF14071.6 KUM59397.1 - 0.22 11.8 7.3 0.46 10.8 1.3 2.4 1 1 1 2 2 2 0 Putative coat protein RasGAP_C PF03836.15 KUM59397.1 - 0.24 11.6 10.3 0.49 10.5 1.9 3.0 1 1 2 3 3 3 0 RasGAP C-terminus Syntaxin-6_N PF09177.11 KUM59397.1 - 0.28 11.8 6.1 0.34 11.5 2.6 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal NPV_P10 PF05531.12 KUM59397.1 - 0.3 11.6 5.9 55 4.3 5.9 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1993 PF09351.10 KUM59397.1 - 0.3 11.2 3.0 4.4 7.4 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) Rogdi_lz PF10259.9 KUM59397.1 - 0.6 9.5 5.2 0.44 10.0 0.8 2.0 1 1 1 2 2 2 0 Rogdi leucine zipper containing protein FapA PF03961.13 KUM59397.1 - 0.67 8.5 3.1 0.93 8.0 2.6 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A TPR_MLP1_2 PF07926.12 KUM59397.1 - 0.82 9.7 6.3 0.28 11.3 2.2 1.9 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.13 KUM59397.1 - 0.98 9.1 5.5 0.36 10.5 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Fzo_mitofusin PF04799.13 KUM59397.1 - 1 8.9 9.7 0.28 10.7 1.3 3.7 3 1 0 4 4 4 0 fzo-like conserved region SKA2 PF16740.5 KUM59397.1 - 1.1 9.1 6.7 0.53 10.1 1.4 2.5 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 Spc24 PF08286.11 KUM59397.1 - 3.1 8.1 9.5 4.2e+02 1.2 9.5 3.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.10 KUM59397.1 - 3.6 7.8 8.7 6.5 6.9 4.7 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CLZ PF16526.5 KUM59397.1 - 4.8 7.6 8.6 0.64 10.4 2.1 2.6 3 0 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Snapin_Pallidin PF14712.6 KUM59397.1 - 4.9 7.6 10.3 1.1 9.7 1.9 3.0 1 1 2 3 3 3 0 Snapin/Pallidin DUF16 PF01519.16 KUM59397.1 - 7.8 7.0 8.2 58 4.3 6.0 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Tyr_Deacylase PF02580.16 KUM59398.1 - 7.4e-54 182.2 0.0 8.7e-54 182.0 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Pro_isomerase PF00160.21 KUM59399.1 - 7.5e-48 162.8 0.6 1.1e-47 162.2 0.6 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 KUM59399.1 - 6.1e-05 22.7 1.1 6.1e-05 22.7 1.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KUM59399.1 - 0.00014 21.7 9.9 0.00041 20.2 1.9 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KUM59399.1 - 0.011 15.5 3.9 18 5.1 0.1 3.5 3 0 0 3 3 3 0 TPR repeat TPR_8 PF13181.6 KUM59399.1 - 0.011 15.9 1.0 0.011 15.9 1.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KUM59399.1 - 0.015 15.5 0.7 0.25 11.5 0.7 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KUM59399.1 - 0.061 14.2 2.5 0.23 12.3 1.3 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KUM59399.1 - 0.072 13.4 3.4 0.4 11.0 3.3 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KUM59399.1 - 0.31 11.7 7.2 1.6 9.4 6.7 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat MIF4G PF02854.19 KUM59400.1 - 1.7e-19 70.3 0.1 3.9e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KUM59400.1 - 2.9e-18 65.9 0.0 9.1e-18 64.3 0.0 1.9 1 0 0 1 1 1 1 MA3 domain Not3 PF04065.15 KUM59401.1 - 3.5e-87 291.7 17.2 4.9e-87 291.2 17.2 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KUM59401.1 - 4.4e-44 149.7 11.5 8.9e-44 148.7 11.5 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Cep57_MT_bd PF06657.13 KUM59401.1 - 0.019 15.4 8.4 0.26 11.8 0.7 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Syntaxin_2 PF14523.6 KUM59401.1 - 0.029 14.7 2.1 0.029 14.7 2.1 2.3 3 0 0 3 3 3 0 Syntaxin-like protein Snapin_Pallidin PF14712.6 KUM59401.1 - 0.046 14.1 0.5 0.046 14.1 0.5 2.6 2 1 1 3 3 3 0 Snapin/Pallidin DUF2373 PF10180.9 KUM59401.1 - 0.068 13.0 5.4 0.03 14.2 2.4 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) DUF1192 PF06698.11 KUM59401.1 - 0.12 12.5 1.9 0.56 10.3 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) FlaC_arch PF05377.11 KUM59401.1 - 0.12 12.8 3.0 2.6 8.5 0.0 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) LZ_Tnp_IS66 PF13007.7 KUM59401.1 - 1.5 9.7 9.0 4.8 8.0 0.3 3.7 3 0 0 3 3 3 0 Transposase C of IS166 homeodomain zf-C2H2 PF00096.26 KUM59402.1 - 1.2e-06 28.6 13.1 4.4e-05 23.7 1.9 3.3 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM59402.1 - 0.001 19.7 1.8 0.001 19.7 1.8 3.3 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2HE PF16278.5 KUM59402.1 - 0.0019 18.6 0.2 0.019 15.4 0.0 2.2 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KUM59402.1 - 0.022 14.8 7.9 0.2 11.7 1.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Sugar_tr PF00083.24 KUM59403.1 - 3.4e-86 289.9 20.8 4e-86 289.7 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM59403.1 - 3.9e-22 78.6 48.3 2.1e-16 59.8 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KUM59403.1 - 2.9 6.1 15.0 0.84 7.8 2.3 3.2 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KUM59404.1 - 1.8e-43 148.8 22.0 1.8e-43 148.8 22.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM59404.1 - 1.9e-09 36.9 9.9 4.3e-09 35.8 9.9 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KUM59404.1 - 6e-06 25.0 4.3 9.2e-06 24.4 4.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) nsp9 PF08710.10 KUM59404.1 - 0.036 14.5 0.0 0.069 13.5 0.0 1.4 1 0 0 1 1 1 0 nsp9 replicase Pyr_redox_2 PF07992.14 KUM59405.1 - 4.7e-67 226.3 8.6 4.7e-67 226.3 8.6 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KUM59405.1 - 2.4e-41 140.4 1.0 5.9e-41 139.2 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KUM59405.1 - 6.3e-20 71.5 9.9 4e-19 68.9 1.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KUM59405.1 - 1.5e-10 41.1 9.9 1.5e-10 41.0 0.9 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KUM59405.1 - 8.8e-10 38.7 3.7 4.9e-05 23.5 0.4 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KUM59405.1 - 4.4e-08 32.6 14.0 1e-06 28.1 5.6 3.0 2 2 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KUM59405.1 - 7.4e-08 32.0 7.6 2e-06 27.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM59405.1 - 6.6e-07 28.8 3.3 6.6e-07 28.8 3.3 3.1 2 1 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 KUM59405.1 - 1.1e-06 28.1 0.5 0.014 14.6 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KUM59405.1 - 9.1e-06 25.1 9.1 0.00088 18.6 1.1 3.1 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KUM59405.1 - 0.00032 20.4 14.5 0.039 13.5 0.5 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KUM59405.1 - 0.0018 17.1 1.9 0.0018 17.1 1.9 3.7 4 0 0 4 4 4 1 HI0933-like protein Thi4 PF01946.17 KUM59405.1 - 0.0038 16.5 1.8 0.0038 16.5 1.8 2.5 1 1 1 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KUM59405.1 - 0.0052 15.9 2.9 0.06 12.4 0.2 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KUM59405.1 - 0.0094 15.2 6.9 0.57 9.4 0.3 2.7 3 0 0 3 3 3 2 FAD binding domain NAD_binding_7 PF13241.6 KUM59405.1 - 0.44 11.0 4.3 0.65 10.5 0.5 3.0 3 1 0 3 3 3 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KUM59405.1 - 4.8 7.0 11.1 0.036 13.9 1.8 2.2 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 KUM59405.1 - 5.7 5.7 7.5 1.2 7.9 0.8 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Asparaginase PF00710.20 KUM59406.1 - 2e-48 164.5 0.8 2e-48 164.5 0.8 1.5 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KUM59406.1 - 1.6e-20 73.4 0.0 3.3e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Glyco_hydro_16 PF00722.21 KUM59408.1 - 2.3e-06 27.2 0.2 3.4e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WD40 PF00400.32 KUM59410.1 - 1.3e-41 139.7 20.2 1.3e-07 32.2 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM59410.1 - 4e-10 39.8 0.7 0.45 10.8 0.0 6.4 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KUM59410.1 - 2.2e-08 33.2 7.6 0.018 13.7 0.1 5.7 2 1 4 6 6 6 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KUM59410.1 - 3.4e-06 26.6 0.0 0.0055 16.1 0.0 3.1 1 1 2 3 3 3 2 WD40-like domain PALB2_WD40 PF16756.5 KUM59410.1 - 9.3e-05 21.5 4.1 0.33 9.8 0.0 4.1 2 1 1 4 4 4 2 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 KUM59410.1 - 0.013 15.1 5.6 0.08 12.5 1.2 3.4 1 1 2 3 3 3 0 PQQ-like domain Pkinase PF00069.25 KUM59411.1 - 4.4e-21 75.4 0.0 3.4e-20 72.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM59411.1 - 8.1e-13 48.2 0.0 7.1e-09 35.3 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KUM59411.1 - 9.1e-05 21.4 0.0 0.0049 15.7 0.0 2.0 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KUM59411.1 - 0.0031 17.5 0.2 0.25 11.2 0.5 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 KUM59411.1 - 0.0062 16.2 0.0 0.0087 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KUM59411.1 - 0.027 13.8 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KUM59411.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family zf-Tim10_DDP PF02953.15 KUM59412.1 - 2.1e-21 75.3 0.9 2.7e-21 75.0 0.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Lectin_leg-like PF03388.13 KUM59413.1 - 2.9e-63 213.3 0.0 3.9e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KUM59413.1 - 5.2e-08 33.1 0.0 8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial lectin PAP_PilO PF06864.12 KUM59413.1 - 0.035 12.9 0.0 0.062 12.1 0.0 1.4 1 0 0 1 1 1 0 Pilin accessory protein (PilO) PBP1_TM PF14812.6 KUM59413.1 - 0.047 14.1 0.0 0.088 13.2 0.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PRCC PF10253.9 KUM59416.1 - 1.7e-36 127.0 4.3 1.7e-36 127.0 4.3 3.6 2 2 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Pkinase PF00069.25 KUM59417.1 - 5.6e-71 239.0 0.0 6.9e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM59417.1 - 4.5e-37 127.7 0.0 6e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM59417.1 - 1.7e-06 27.5 0.0 3.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KUM59417.1 - 0.0074 15.9 0.1 0.32 10.6 0.1 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KUM59417.1 - 0.015 15.2 0.1 0.034 14.1 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Mito_carr PF00153.27 KUM59418.1 - 1.1e-45 153.4 6.5 1.2e-15 57.2 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4140 PF13600.6 KUM59419.1 - 0.025 15.0 0.3 0.051 14.0 0.3 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF155 PF02582.14 KUM59420.1 - 2.5e-52 177.5 0.1 4.5e-52 176.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 KUM59420.1 - 0.046 14.2 0.0 0.16 12.4 0.0 2.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 CTK3 PF12243.8 KUM59422.1 - 1.8e-51 173.3 0.2 3.4e-51 172.4 0.2 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KUM59422.1 - 7.4e-17 61.3 9.7 7.4e-17 61.3 9.7 2.0 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus DUF3873 PF12989.7 KUM59422.1 - 0.058 13.8 0.2 0.18 12.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) UPF0242 PF06785.11 KUM59422.1 - 3.3 7.8 9.2 0.28 11.3 4.4 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus U3_snoRNA_assoc PF08297.11 KUM59423.1 - 7.5e-17 61.8 1.2 7.5e-17 61.8 1.2 3.5 3 1 0 3 3 3 1 U3 snoRNA associated DUF4355 PF14265.6 KUM59423.1 - 0.02 15.1 12.2 0.052 13.8 12.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Cwf_Cwc_15 PF04889.12 KUM59423.1 - 0.097 12.4 21.7 0.031 14.0 19.1 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RRP14 PF15459.6 KUM59423.1 - 0.69 10.6 14.6 0.28 11.8 7.1 2.8 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 RRN3 PF05327.11 KUM59423.1 - 7.4 5.0 6.8 11 4.4 6.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AAA_5 PF07728.14 KUM59424.1 - 2.2e-128 422.9 0.1 6.9e-22 77.9 0.0 9.7 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KUM59424.1 - 3.9e-49 165.3 6.8 7.1e-18 64.8 0.0 5.5 5 0 0 5 5 4 4 Midasin AAA lid domain AAA_7 PF12775.7 KUM59424.1 - 3.2e-30 105.0 1.5 3e-05 23.6 0.0 7.3 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA_lid_5 PF17865.1 KUM59424.1 - 8.6e-30 102.9 0.6 7.2e-28 96.8 0.0 3.1 3 0 0 3 3 2 1 Midasin AAA lid domain AAA_3 PF07726.11 KUM59424.1 - 9.9e-30 103.1 0.0 8.7e-11 41.8 0.0 7.4 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KUM59424.1 - 8e-28 97.5 0.0 0.00028 21.3 0.0 7.0 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KUM59424.1 - 1.3e-25 90.7 9.0 3.6e-05 24.2 0.1 8.7 6 1 0 6 6 6 5 AAA ATPase domain Dynein_heavy PF03028.15 KUM59424.1 - 1.5e-22 79.9 0.0 1.1e-05 25.5 0.0 7.7 8 0 0 8 8 7 4 Dynein heavy chain region D6 P-loop domain AAA_33 PF13671.6 KUM59424.1 - 2.8e-19 69.7 0.0 0.0011 19.1 0.0 7.1 6 0 0 6 6 6 3 AAA domain AAA_30 PF13604.6 KUM59424.1 - 3.2e-18 66.1 0.0 0.0047 16.7 0.0 7.7 6 2 0 6 6 6 4 AAA domain AAA_22 PF13401.6 KUM59424.1 - 9.4e-18 64.8 0.2 0.063 13.6 0.0 8.4 7 0 0 7 7 7 4 AAA domain AAA_18 PF13238.6 KUM59424.1 - 6.2e-17 62.4 0.3 0.021 15.4 0.0 7.2 6 0 0 6 6 6 2 AAA domain AAA_14 PF13173.6 KUM59424.1 - 9.1e-17 61.3 0.0 0.011 15.7 0.0 7.3 7 0 0 7 7 6 3 AAA domain TsaE PF02367.17 KUM59424.1 - 9e-16 58.0 3.3 0.16 12.0 0.0 6.8 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KUM59424.1 - 2.6e-15 57.1 2.6 0.0043 17.6 0.0 7.2 7 0 0 7 7 6 3 ABC transporter AAA_6 PF12774.7 KUM59424.1 - 4.3e-15 55.5 0.0 0.074 12.0 0.0 8.1 8 0 0 8 8 8 2 Hydrolytic ATP binding site of dynein motor region Sigma54_activat PF00158.26 KUM59424.1 - 3.3e-14 52.9 0.0 0.014 15.1 0.0 5.9 6 0 0 6 6 6 3 Sigma-54 interaction domain Mg_chelatase PF01078.21 KUM59424.1 - 5.2e-13 48.8 0.4 1.9 7.8 0.0 8.7 9 0 0 9 9 9 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KUM59424.1 - 6.4e-13 48.4 1.7 0.79 9.0 0.0 7.5 7 0 0 7 7 7 2 Zeta toxin RNA_helicase PF00910.22 KUM59424.1 - 2e-12 47.4 0.6 0.91 9.9 0.0 6.8 6 0 0 6 6 6 2 RNA helicase NACHT PF05729.12 KUM59424.1 - 1e-11 45.1 8.8 0.076 12.9 0.1 6.5 6 0 0 6 6 5 3 NACHT domain RsgA_GTPase PF03193.16 KUM59424.1 - 1.5e-11 44.5 2.6 0.083 12.8 0.1 6.3 6 0 0 6 6 6 2 RsgA GTPase SRP54 PF00448.22 KUM59424.1 - 1.5e-11 44.3 3.1 0.072 12.7 0.0 6.0 6 0 0 6 6 6 2 SRP54-type protein, GTPase domain RuvB_N PF05496.12 KUM59424.1 - 4.5e-11 42.7 6.4 0.34 10.7 0.0 7.3 7 0 0 7 7 7 3 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KUM59424.1 - 2.4e-10 40.9 3.8 0.51 10.7 0.1 6.9 6 1 0 6 6 5 1 AAA domain AAA_28 PF13521.6 KUM59424.1 - 3e-10 40.6 3.8 0.24 11.6 0.0 6.8 6 0 0 6 6 6 2 AAA domain MMR_HSR1 PF01926.23 KUM59424.1 - 2.6e-09 37.2 1.4 0.039 14.0 0.0 6.5 6 0 0 6 6 6 1 50S ribosome-binding GTPase Sigma54_activ_2 PF14532.6 KUM59424.1 - 3.3e-09 37.0 0.3 0.098 12.8 0.1 5.3 5 0 0 5 5 5 2 Sigma-54 interaction domain ATPase_2 PF01637.18 KUM59424.1 - 3.7e-09 36.9 0.1 1.9 8.3 0.0 6.1 6 0 0 6 6 6 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KUM59424.1 - 7.2e-09 35.5 4.0 2.1 7.9 0.0 6.2 6 0 0 6 6 5 2 AAA domain Rad17 PF03215.15 KUM59424.1 - 7.3e-09 35.8 0.3 0.27 11.1 0.0 5.7 5 0 0 5 5 5 1 Rad17 P-loop domain PduV-EutP PF10662.9 KUM59424.1 - 7.6e-09 35.4 3.4 0.14 11.9 0.0 5.9 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 KUM59424.1 - 2.5e-08 33.5 1.5 1.6 8.6 0.0 6.3 6 0 0 6 6 6 1 P-loop containing region of AAA domain Roc PF08477.13 KUM59424.1 - 9.7e-08 32.3 1.5 11 6.3 0.0 6.4 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KUM59424.1 - 1.2e-07 31.2 2.0 0.6 9.2 0.1 5.5 6 0 0 6 6 6 2 Protein of unknown function (DUF815) T2SSE PF00437.20 KUM59424.1 - 1.3e-07 31.0 2.7 0.25 10.4 0.0 6.0 6 0 0 6 6 6 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 KUM59424.1 - 1.9e-07 31.0 0.1 2.7 7.7 0.0 5.6 5 0 0 5 5 5 1 IstB-like ATP binding protein TniB PF05621.11 KUM59424.1 - 3.7e-07 29.7 0.1 1.7 8.0 0.0 5.9 6 0 0 6 6 5 1 Bacterial TniB protein MCM PF00493.23 KUM59424.1 - 4.6e-07 29.2 0.1 0.68 9.0 0.0 4.9 5 0 0 5 5 5 1 MCM P-loop domain AAA_24 PF13479.6 KUM59424.1 - 1.6e-06 28.0 1.1 2.7 7.6 0.0 6.0 7 0 0 7 7 5 1 AAA domain Viral_helicase1 PF01443.18 KUM59424.1 - 2.5e-06 27.4 0.1 0.32 10.7 0.0 5.1 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.17 KUM59424.1 - 2.6e-06 27.4 2.8 3.1 7.5 0.0 6.0 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KUM59424.1 - 3.6e-06 27.0 6.1 2.5 8.0 0.1 5.7 5 0 0 5 5 5 1 NTPase SRPRB PF09439.10 KUM59424.1 - 1.5e-05 24.6 3.0 2.3 7.6 0.0 6.0 6 0 0 6 6 6 1 Signal recognition particle receptor beta subunit Bac_DnaA PF00308.18 KUM59424.1 - 1.5e-05 24.9 0.1 2.1 8.1 0.0 4.3 5 0 0 5 5 3 1 Bacterial dnaA protein AAA_9 PF12781.7 KUM59424.1 - 2.1e-05 23.7 0.0 0.091 11.9 0.0 4.5 5 0 0 5 5 4 1 ATP-binding dynein motor region cobW PF02492.19 KUM59424.1 - 0.00011 21.9 6.7 3.3 7.3 0.1 6.1 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.15 KUM59424.1 - 0.00014 21.9 0.1 4.9 7.1 0.0 4.8 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit TIP49 PF06068.13 KUM59424.1 - 0.00025 20.3 1.4 0.88 8.7 0.0 4.7 5 0 0 5 5 5 1 TIP49 P-loop domain CbiA PF01656.23 KUM59424.1 - 0.00028 21.0 0.0 0.67 10.0 0.0 3.9 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain PhoH PF02562.16 KUM59424.1 - 0.0003 20.3 0.4 2.2 7.7 0.0 4.3 4 0 0 4 4 4 1 PhoH-like protein NB-ARC PF00931.22 KUM59424.1 - 0.0031 16.7 3.6 8.5 5.5 0.0 5.1 6 0 0 6 6 4 0 NB-ARC domain CPT PF07931.12 KUM59424.1 - 0.0032 17.3 0.1 4 7.3 0.0 5.1 4 1 0 4 4 3 0 Chloramphenicol phosphotransferase-like protein DnaB_C PF03796.15 KUM59424.1 - 0.0039 16.6 4.9 2.3 7.5 0.0 4.6 4 0 0 4 4 4 1 DnaB-like helicase C terminal domain ATPase PF06745.13 KUM59424.1 - 0.0046 16.3 1.4 29 3.9 0.0 5.0 5 0 0 5 5 5 0 KaiC FeoB_N PF02421.18 KUM59424.1 - 0.0058 16.2 5.9 0.65 9.5 0.0 5.1 6 0 0 6 6 5 1 Ferrous iron transport protein B MobB PF03205.14 KUM59424.1 - 0.0069 16.3 7.4 44 4.0 0.0 5.9 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.10 KUM59424.1 - 0.012 15.1 0.1 3.5 7.0 0.0 3.8 3 0 0 3 3 3 0 Chromatin associated protein KTI12 dNK PF01712.19 KUM59424.1 - 0.038 13.8 1.5 15 5.3 0.0 4.2 4 0 0 4 4 3 0 Deoxynucleoside kinase SUD-M PF11633.8 KUM59424.1 - 0.047 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain DEAD PF00270.29 KUM59424.1 - 0.07 12.9 0.5 19 5.0 0.0 3.7 4 0 0 4 4 3 0 DEAD/DEAH box helicase Septin PF00735.18 KUM59424.1 - 0.12 11.6 2.1 7.1 5.8 0.0 4.1 6 0 0 6 6 5 0 Septin MeaB PF03308.16 KUM59424.1 - 0.13 11.2 3.1 5.2 6.0 0.2 3.0 3 0 0 3 3 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 KUM59424.1 - 0.36 10.3 1.8 14 5.1 0.1 4.1 6 0 0 6 6 4 0 ADP-ribosylation factor family DAP3 PF10236.9 KUM59424.1 - 0.62 9.2 7.2 10 5.2 0.0 4.4 5 0 0 5 5 5 0 Mitochondrial ribosomal death-associated protein 3 Voltage_CLC PF00654.20 KUM59425.1 - 2.5e-90 303.3 26.4 2.5e-90 303.3 26.4 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KUM59425.1 - 0.00015 22.2 0.0 0.2 12.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain Comm PF15957.5 KUM59425.1 - 0.23 11.8 0.4 1.4 9.3 0.3 2.2 2 0 0 2 2 2 0 Commissureless DUF3716 PF12511.8 KUM59426.1 - 6.6e-13 48.5 10.7 9.8e-13 47.9 10.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Zn_clus PF00172.18 KUM59427.1 - 2.7e-08 33.8 7.2 6e-08 32.7 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM59427.1 - 3e-05 23.0 1.0 3.9e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4692 PF15763.5 KUM59427.1 - 0.25 11.8 2.7 20 5.6 1.4 2.2 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Actin PF00022.19 KUM59428.1 - 4.8e-127 424.0 0.0 3e-126 421.3 0.0 1.8 1 1 0 1 1 1 1 Actin Glyco_tran_28_C PF04101.16 KUM59429.1 - 8.7e-19 68.1 0.1 2.1e-18 66.9 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF3602 PF12223.8 KUM59430.1 - 4.1e-23 81.8 6.2 1.2e-20 73.8 0.3 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Pet127 PF08634.10 KUM59432.1 - 0.22 10.9 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial protein Pet127 AAA PF00004.29 KUM59433.1 - 4.2e-25 88.7 0.0 1.2e-13 51.6 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 KUM59433.1 - 7.9e-10 38.8 2.0 4.9e-09 36.2 0.1 3.0 3 0 0 3 3 2 1 AAA lid domain AAA_5 PF07728.14 KUM59433.1 - 6.6e-06 26.2 0.1 0.047 13.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KUM59433.1 - 8.2e-06 25.7 1.1 0.014 15.1 0.0 3.2 3 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KUM59433.1 - 0.00012 21.9 0.0 0.45 10.2 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KUM59433.1 - 0.00015 21.2 0.0 0.16 11.4 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KUM59433.1 - 0.00022 21.6 1.8 4 7.8 0.0 3.6 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.12 KUM59433.1 - 0.00082 19.1 0.0 0.56 9.9 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KUM59433.1 - 0.0019 18.5 2.3 3.3 8.0 0.4 4.2 2 2 1 3 3 3 1 AAA domain Torsin PF06309.11 KUM59433.1 - 0.0024 17.9 0.0 1.6 8.9 0.0 2.7 3 0 0 3 3 2 1 Torsin AAA_24 PF13479.6 KUM59433.1 - 0.0028 17.4 1.2 1.8 8.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KUM59433.1 - 0.0055 16.2 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_16 PF13191.6 KUM59433.1 - 0.0069 16.8 2.9 1.6 9.1 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 KUM59433.1 - 0.01 16.2 0.1 2.2 8.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_11 PF13086.6 KUM59433.1 - 0.027 14.3 12.6 0.28 10.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain zf-U1 PF06220.12 KUM59434.1 - 8.6e-07 28.6 0.8 1.1e-06 28.2 0.8 1.2 1 0 0 1 1 1 1 U1 zinc finger MFS_1 PF07690.16 KUM59436.1 - 1.2e-15 57.3 18.6 3.2e-15 55.9 9.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UL42 PF17638.2 KUM59436.1 - 0.16 11.9 0.1 0.45 10.5 0.1 1.7 1 0 0 1 1 1 0 HCMV UL42 Aldedh PF00171.22 KUM59437.1 - 1.4e-79 267.8 0.0 1.6e-79 267.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Adap_comp_sub PF00928.21 KUM59438.1 - 2.6e-61 207.3 0.0 1.1e-60 205.3 0.0 1.8 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KUM59438.1 - 6.9e-05 22.8 0.1 0.00011 22.1 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain YL1 PF05764.13 KUM59438.1 - 0.012 15.8 1.9 0.016 15.3 1.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein SWIRM-assoc_2 PF16496.5 KUM59438.1 - 0.17 10.7 5.1 0.24 10.2 5.1 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal SRP-alpha_N PF04086.13 KUM59438.1 - 0.23 11.3 5.9 0.34 10.8 5.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4588 PF15251.6 KUM59439.1 - 8.7e-07 29.0 0.8 5.3e-06 26.4 0.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) DUF4536 PF15055.6 KUM59440.1 - 6.2e-06 26.3 5.5 3.2e-05 24.1 5.5 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) SpoU_methylase PF00588.19 KUM59441.1 - 1.7e-24 86.6 0.1 4.3e-23 82.0 0.1 2.5 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KUM59441.1 - 2.1e-07 31.1 0.0 3.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding ADH_zinc_N PF00107.26 KUM59442.1 - 1.8e-22 79.7 0.8 3.1e-22 78.9 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM59442.1 - 2.5e-19 69.2 0.8 3.4e-19 68.7 0.2 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KUM59442.1 - 2.1e-07 30.6 2.5 3.4e-07 30.0 1.8 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KUM59442.1 - 2.3e-05 25.4 0.0 5.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KUM59442.1 - 0.0095 15.3 0.8 0.014 14.7 0.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KUM59442.1 - 0.062 12.9 0.2 0.24 10.9 0.1 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 KUM59442.1 - 0.075 13.7 0.1 0.15 12.8 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain IlvN PF07991.12 KUM59442.1 - 0.076 12.6 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Methyltransf_18 PF12847.7 KUM59442.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Asp PF00026.23 KUM59443.1 - 3.9e-68 230.2 3.2 4.6e-68 230.0 3.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KUM59443.1 - 2.5e-12 47.4 1.7 1.2e-07 32.2 0.0 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KUM59443.1 - 0.00074 20.1 2.3 0.18 12.5 0.7 3.1 2 1 0 2 2 2 2 Aspartyl protease SNF2_N PF00176.23 KUM59444.1 - 6.8e-78 261.8 0.1 1.1e-77 261.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KUM59444.1 - 4.6e-41 139.4 1.4 1.6e-40 137.6 1.4 2.1 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 KUM59444.1 - 6.3e-38 130.0 2.4 6.3e-38 130.0 2.4 3.3 4 0 0 4 4 3 1 HAND Helicase_C PF00271.31 KUM59444.1 - 4.1e-18 65.8 0.0 4.7e-17 62.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM59444.1 - 4.1e-12 46.4 0.3 2.1e-11 44.1 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KUM59444.1 - 2.5e-06 26.9 0.0 1.1e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KUM59444.1 - 3e-05 23.9 0.0 7.6e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KUM59444.1 - 8.9e-05 22.3 0.0 0.00024 20.8 0.0 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD_2 PF06733.15 KUM59444.1 - 0.0058 16.3 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 Myb_DNA-binding PF00249.31 KUM59444.1 - 0.035 14.3 0.0 2.7 8.3 0.0 2.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF1086 PF06461.11 KUM59444.1 - 0.039 13.8 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) AAA_14 PF13173.6 KUM59444.1 - 0.043 13.8 0.1 0.17 11.9 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KUM59444.1 - 0.11 12.8 0.1 0.48 10.7 0.0 2.2 2 0 0 2 2 1 0 AAA domain MRP-S28 PF10213.9 KUM59445.1 - 1.3e-45 154.9 0.1 2.4e-45 154.0 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DnaB_bind PF10410.9 KUM59445.1 - 0.021 15.0 0.1 1.6 9.0 0.0 2.5 1 1 1 2 2 2 0 DnaB-helicase binding domain of primase Torus PF16131.5 KUM59446.1 - 0.012 16.3 0.2 0.036 14.8 0.2 1.8 1 0 0 1 1 1 0 Torus domain zf-PHD-like PF15446.6 KUM59448.1 - 6.6e-52 175.5 11.1 1.6e-51 174.3 11.1 1.7 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 KUM59448.1 - 9.7e-51 172.5 0.0 1.8e-50 171.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 KUM59448.1 - 1.1e-21 76.5 0.4 3.9e-21 74.7 0.4 2.1 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 KUM59448.1 - 2.8e-19 69.5 0.0 1e-18 67.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KUM59448.1 - 6.8e-14 51.7 1.5 1.5e-13 50.6 1.5 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 KUM59448.1 - 3.1e-05 23.8 19.1 0.00084 19.2 6.3 3.7 3 1 1 4 4 4 2 PHD-finger ResIII PF04851.15 KUM59448.1 - 0.00012 22.2 0.0 0.00031 20.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Chromo PF00385.24 KUM59448.1 - 0.003 17.5 5.8 1 9.3 0.1 3.6 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain zf-piccolo PF05715.13 KUM59448.1 - 1.1 9.4 4.4 0.76 10.0 1.2 2.4 2 0 0 2 2 2 0 Piccolo Zn-finger PHD_2 PF13831.6 KUM59448.1 - 3.8 7.2 12.3 1.8 8.2 6.4 3.1 2 1 1 3 3 3 0 PHD-finger BCAS2 PF05700.11 KUM59449.1 - 4.2e-61 206.2 8.0 5e-61 206.0 8.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Ceramidase_alk PF04734.13 KUM59450.1 - 2.3e-211 702.8 0.0 2.7e-211 702.6 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KUM59450.1 - 3e-59 199.7 0.1 4.6e-59 199.1 0.1 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal IMCp PF12314.8 KUM59451.1 - 0.037 14.3 0.4 0.095 13.0 0.0 1.8 2 0 0 2 2 2 0 Inner membrane complex protein HAD_2 PF13419.6 KUM59453.1 - 0.0046 17.1 0.0 0.0058 16.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase EI24 PF07264.11 KUM59454.1 - 3.4e-15 56.7 13.6 4.6e-15 56.3 13.6 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Zn_clus PF00172.18 KUM59455.1 - 2e-08 34.2 9.4 2e-08 34.2 9.4 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM59455.1 - 0.00018 20.7 0.1 0.00042 19.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain GTP_EFTU PF00009.27 KUM59456.1 - 6.5e-30 104.1 2.8 1.9e-28 99.3 2.8 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KUM59456.1 - 2.2e-28 98.4 1.2 8.9e-28 96.5 0.5 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 IF2_N PF04760.15 KUM59456.1 - 2.6e-09 36.8 0.0 6.6e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 KUM59456.1 - 3e-09 37.0 0.1 9.4e-09 35.4 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KUM59456.1 - 0.00018 21.5 0.2 0.08 12.8 0.0 2.5 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KUM59456.1 - 0.0067 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.25 KUM59456.1 - 0.028 14.8 1.9 4 7.9 0.1 2.8 2 0 0 2 2 2 0 Elongation factor Tu domain 2 zf-C3HC4_3 PF13920.6 KUM59456.1 - 0.33 10.8 2.1 0.68 9.8 2.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.18 KUM59456.1 - 0.66 9.3 4.0 1.3 8.4 4.0 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others UPF0547 PF10571.9 KUM59456.1 - 1.4 9.1 3.5 2.9 8.0 3.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Mito_carr PF00153.27 KUM59457.1 - 8e-58 192.4 3.7 1e-19 70.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GP38 PF05268.11 KUM59459.1 - 0.88 9.2 15.1 0.91 9.1 15.1 1.1 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 3Beta_HSD PF01073.19 KUM59460.1 - 2.4e-26 92.4 0.0 6.8e-26 90.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KUM59460.1 - 3.6e-12 46.3 0.0 5.8e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KUM59460.1 - 3.8e-12 45.9 0.0 5.6e-10 38.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KUM59460.1 - 8e-06 25.9 0.0 5e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KUM59460.1 - 0.00025 20.6 0.0 0.0006 19.3 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KUM59460.1 - 0.00056 19.1 0.0 0.00093 18.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KUM59460.1 - 0.0047 16.1 0.0 0.061 12.4 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 KUM59460.1 - 0.15 12.0 1.0 1.2 9.0 1.0 2.2 1 1 0 1 1 1 0 KR domain Pkinase PF00069.25 KUM59461.1 - 2.9e-41 141.6 0.0 4.2e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM59461.1 - 2.1e-29 102.6 0.0 2.9e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KUM59461.1 - 0.1 12.5 0.0 11 5.9 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Med10 PF09748.9 KUM59462.1 - 2e-43 147.2 0.0 2.3e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 KUM59462.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) ILVD_EDD PF00920.21 KUM59463.1 - 2.7e-155 517.9 0.0 3.2e-155 517.7 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family MFS_1 PF07690.16 KUM59464.1 - 7.3e-21 74.5 53.7 1.8e-13 50.1 22.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM59464.1 - 4.5e-05 22.1 24.9 5.7e-05 21.7 24.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gemini_mov PF01708.16 KUM59464.1 - 0.33 10.7 3.5 13 5.7 0.0 3.4 3 0 0 3 3 3 0 Geminivirus putative movement protein Fungal_trans PF04082.18 KUM59465.1 - 3.2e-23 82.1 1.4 4.9e-23 81.5 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fe_dep_repress PF01325.19 KUM59465.1 - 0.065 13.4 0.3 0.11 12.7 0.3 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HpcH_HpaI PF03328.14 KUM59466.1 - 2.4e-27 95.5 0.0 2.7e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 KUM59466.1 - 0.17 11.0 0.0 1.5 7.8 0.0 2.0 2 0 0 2 2 2 0 PEP-utilising enzyme, TIM barrel domain Scs3p PF10261.9 KUM59468.1 - 3e-72 243.1 3.7 4e-72 242.7 3.7 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF4199 PF13858.6 KUM59468.1 - 0.34 11.3 6.1 0.23 11.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Erythro_esteras PF05139.14 KUM59469.1 - 1.5e-124 416.3 2.6 1.7e-124 416.1 2.6 1.0 1 0 0 1 1 1 1 Erythromycin esterase FAD_binding_2 PF00890.24 KUM59471.1 - 2.7e-85 287.0 0.8 3.3e-85 286.7 0.8 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KUM59471.1 - 6.6e-20 71.0 0.2 4.7e-19 68.3 0.0 2.5 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KUM59471.1 - 5.4e-15 55.8 0.5 1.4e-14 54.4 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KUM59471.1 - 6.1e-08 32.8 0.7 3.8e-07 30.2 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM59471.1 - 6.8e-08 32.1 0.8 4.3e-06 26.2 0.6 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KUM59471.1 - 1.2e-07 31.5 1.7 3.6e-07 29.9 1.7 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KUM59471.1 - 7.6e-07 28.7 0.1 0.011 15.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KUM59471.1 - 9.6e-07 27.8 0.8 0.0048 15.6 0.1 3.2 3 0 0 3 3 3 3 HI0933-like protein FAD_binding_3 PF01494.19 KUM59471.1 - 1.7e-06 27.6 0.1 2.5e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KUM59471.1 - 8.6e-06 25.2 0.5 0.0025 17.1 0.2 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KUM59471.1 - 0.0042 16.2 3.5 0.15 11.1 1.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 KUM59471.1 - 0.0045 16.3 0.2 1.4 8.1 0.1 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KUM59471.1 - 0.028 15.0 3.3 6.5 7.4 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TORC_M PF12885.7 KUM59471.1 - 0.031 14.2 1.3 0.08 12.9 0.2 2.2 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain AlaDh_PNT_C PF01262.21 KUM59471.1 - 0.045 13.1 0.7 0.11 11.8 0.7 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TFIIA PF03153.13 KUM59472.1 - 4.9 7.0 8.4 7.6 6.4 8.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Endosulfine PF04667.17 KUM59473.1 - 6.5e-15 55.0 0.1 1e-14 54.4 0.1 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Aldedh PF00171.22 KUM59475.1 - 1e-134 449.6 1.8 1.2e-134 449.3 1.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HopA1 PF17914.1 KUM59475.1 - 0.041 13.6 0.0 10 5.8 0.0 2.3 2 0 0 2 2 2 0 HopA1 effector protein family PCI PF01399.27 KUM59477.1 - 1.3e-12 48.1 0.0 3.6e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 KUM59477.1 - 5.2e-06 26.3 0.2 8.8e-06 25.5 0.2 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PspA_IM30 PF04012.12 KUM59477.1 - 0.0035 16.9 1.9 0.0065 16.1 1.9 1.4 1 0 0 1 1 1 1 PspA/IM30 family TPR_19 PF14559.6 KUM59477.1 - 0.016 15.7 2.3 0.51 10.9 0.4 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Herpes_UL14 PF03580.14 KUM59477.1 - 0.06 13.6 1.9 4.9 7.4 0.1 2.4 1 1 1 2 2 2 0 Herpesvirus UL14-like protein TPR_16 PF13432.6 KUM59477.1 - 0.079 13.6 3.8 1.4 9.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KUM59477.1 - 1.6 9.7 6.8 26 6.0 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_17 PF00332.18 KUM59478.1 - 0.011 15.4 2.3 0.023 14.3 1.7 1.8 1 1 1 2 2 2 0 Glycosyl hydrolases family 17 AcetylCoA_hydro PF02550.15 KUM59481.1 - 1.2e-48 165.7 0.0 1.9e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KUM59481.1 - 1.2e-39 135.7 0.0 2e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Sin3a_C PF16879.5 KUM59482.1 - 1.4e-76 258.0 4.5 1.4e-76 258.0 4.5 3.5 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 KUM59482.1 - 5.8e-41 138.4 3.0 1.3e-17 63.7 0.0 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KUM59482.1 - 5.6e-39 132.2 0.0 2.2e-38 130.3 0.0 2.1 1 0 0 1 1 1 1 Sin3 family co-repressor TSP_NTD PF17804.1 KUM59482.1 - 1.6 9.0 9.3 0.037 14.3 0.9 2.6 2 0 0 2 2 2 0 Tail specific protease N-terminal domain WD40 PF00400.32 KUM59484.1 - 6.1e-13 49.0 4.0 0.087 13.7 0.3 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM59484.1 - 0.0079 16.5 0.1 2.8 8.3 0.0 3.8 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_43 PF04616.14 KUM59486.1 - 4.9e-41 140.9 5.3 5.5e-41 140.8 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF5316 PF17247.2 KUM59487.1 - 0.00093 19.2 0.0 0.0019 18.2 0.0 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF5316) LapA_dom PF06305.11 KUM59487.1 - 0.0064 16.3 0.5 0.0096 15.7 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain DUF4834 PF16118.5 KUM59487.1 - 0.0072 17.3 0.0 0.014 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) FAM176 PF14851.6 KUM59487.1 - 0.021 14.5 0.0 0.025 14.3 0.0 1.3 1 1 0 1 1 1 0 FAM176 family EMC3_TMCO1 PF01956.16 KUM59487.1 - 0.046 13.5 0.0 0.062 13.0 0.0 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like CBP_BcsG PF11658.8 KUM59487.1 - 0.15 10.5 0.0 0.18 10.1 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG tRNA_anti-like PF12869.7 KUM59487.1 - 0.19 11.3 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 tRNA_anti-like DUF4190 PF13828.6 KUM59487.1 - 0.98 9.2 5.6 0.25 11.1 2.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4190) NMO PF03060.15 KUM59488.1 - 7.7e-55 186.6 1.2 1.1e-54 186.1 1.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KUM59488.1 - 5.9e-13 48.5 1.5 8.8e-13 48.0 1.5 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KUM59488.1 - 1.1e-07 31.3 1.2 1.6e-07 30.7 1.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KUM59488.1 - 0.0001 21.6 2.3 0.00019 20.7 2.3 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KUM59488.1 - 0.0038 16.5 0.3 0.006 15.8 0.3 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Radial_spoke_3 PF06098.11 KUM59488.1 - 0.056 12.7 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 NmrA PF05368.13 KUM59489.1 - 4e-21 75.6 0.1 5.5e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM59489.1 - 3.6e-20 72.6 0.4 8.2e-20 71.5 0.1 1.7 2 1 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 KUM59489.1 - 2.5e-08 34.1 1.0 1.1e-07 32.0 0.2 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KUM59489.1 - 2.8e-07 30.9 1.4 3.8e-07 30.4 0.3 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KUM59489.1 - 6.5e-05 23.1 0.6 0.00079 19.6 0.1 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KUM59489.1 - 9.4e-05 22.9 2.1 0.0016 19.0 0.3 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KUM59489.1 - 0.00029 20.8 0.2 0.00067 19.6 0.2 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KUM59489.1 - 0.00053 19.5 0.0 0.0012 18.3 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KUM59489.1 - 0.0021 17.1 0.2 0.0054 15.8 0.2 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KUM59489.1 - 0.026 14.8 0.2 0.064 13.5 0.2 1.7 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KUM59489.1 - 0.031 13.6 3.3 0.055 12.8 1.3 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Nore1-SARAH PF16517.5 KUM59491.1 - 0.042 13.7 1.3 0.086 12.8 1.3 1.5 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Zn_clus PF00172.18 KUM59492.1 - 2.8e-09 36.9 7.0 5.5e-09 36.0 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.7 KUM59493.1 - 1.6e-112 368.3 10.4 1.3e-18 67.3 0.1 9.9 3 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM59493.1 - 2.2e-85 280.0 11.3 7.5e-10 39.2 0.1 13.2 5 2 9 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM59493.1 - 2.8e-80 254.6 15.3 5.8e-06 26.3 0.0 17.6 18 0 0 18 18 18 15 Ankyrin repeat Ank_5 PF13857.6 KUM59493.1 - 6.5e-78 255.8 13.8 2.9e-11 43.4 0.1 14.4 2 2 13 16 16 16 14 Ankyrin repeats (many copies) Ank PF00023.30 KUM59493.1 - 1.2e-74 243.7 24.3 5.3e-06 26.6 0.0 17.2 18 0 0 18 18 18 15 Ankyrin repeat ZZ PF00569.17 KUM59493.1 - 0.0072 16.1 4.9 0.016 15.0 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type DUF2724 PF10893.8 KUM59499.1 - 0.11 12.3 0.0 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2724) HeLo PF14479.6 KUM59500.1 - 0.00067 19.5 0.5 0.002 18.0 0.3 1.9 1 1 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.12 KUM59500.1 - 0.0092 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KUM59500.1 - 0.029 14.7 0.0 0.43 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Ribonucleas_3_2 PF11469.8 KUM59500.1 - 0.063 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease III RNA_helicase PF00910.22 KUM59500.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Tim17 PF02466.19 KUM59501.1 - 2.7e-31 108.2 7.8 3.4e-31 107.9 7.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Rhodanese PF00581.20 KUM59502.1 - 5.7e-11 42.9 0.0 6.8e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_28 PF02636.17 KUM59503.1 - 3.4e-81 272.7 0.0 5.1e-81 272.2 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PWI PF01480.17 KUM59504.1 - 6.9e-16 58.3 0.5 1.5e-15 57.3 0.5 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 KUM59504.1 - 0.01 15.6 0.0 0.051 13.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C4H2 PF10146.9 KUM59504.1 - 8.4 6.6 8.4 2.7 8.2 4.9 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein PGI PF00342.19 KUM59505.1 - 1.7e-236 785.5 1.4 2e-236 785.3 1.4 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Ribosomal_S21 PF01165.20 KUM59507.1 - 1.6e-11 43.7 2.6 1.6e-11 43.7 2.6 1.8 2 0 0 2 2 2 1 Ribosomal protein S21 Hamartin PF04388.12 KUM59507.1 - 0.029 13.1 4.0 0.031 13.0 4.0 1.1 1 0 0 1 1 1 0 Hamartin protein Pterin_bind PF00809.22 KUM59508.1 - 5.2e-80 268.7 0.0 6.2e-80 268.4 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KUM59508.1 - 2.6e-23 82.7 0.1 4.5e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) ThiP_synth PF10120.9 KUM59508.1 - 0.042 13.5 0.8 0.091 12.4 0.2 1.8 2 0 0 2 2 2 0 Thiamine-phosphate synthase ArfGap PF01412.18 KUM59509.1 - 1.9e-33 115.0 0.8 3.3e-33 114.2 0.8 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Mcm10 PF09332.11 KUM59509.1 - 0.22 10.9 2.7 0.47 9.8 2.7 1.5 1 0 0 1 1 1 0 Mcm10 replication factor SOG2 PF10428.9 KUM59509.1 - 5.1 6.2 7.8 6.9 5.7 7.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein NAM-associated PF14303.6 KUM59509.1 - 5.4 7.7 7.1 12 6.6 7.1 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain TIM21 PF08294.11 KUM59510.1 - 3.6e-39 133.9 0.0 4.5e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KUM59510.1 - 0.00042 20.0 0.0 0.0011 18.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 MR_MLE_C PF13378.6 KUM59511.1 - 6e-60 202.5 0.0 8.7e-60 202.0 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KUM59511.1 - 2.3e-06 27.8 0.0 5.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Peptidase_Prp PF04327.12 KUM59511.1 - 0.039 14.2 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 Cysteine protease Prp Surp PF01805.20 KUM59512.1 - 1e-12 47.8 0.0 2.6e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Surp module DUF3235 PF11574.8 KUM59512.1 - 0.63 10.9 0.0 0.63 10.9 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3235) TPR_19 PF14559.6 KUM59513.1 - 1.2e-05 25.7 0.8 0.18 12.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KUM59513.1 - 0.0048 16.9 0.1 3 8.2 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KUM59513.1 - 0.014 16.1 0.1 2.6 8.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KUM59513.1 - 0.019 15.2 0.2 0.42 10.9 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KUM59513.1 - 0.03 14.5 0.1 56 4.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KUM59513.1 - 0.048 14.5 3.0 1.1e+02 4.0 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KUM59513.1 - 0.066 13.9 4.5 41 5.2 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SAC3_GANP PF03399.16 KUM59514.1 - 0.00042 19.8 0.0 0.00068 19.1 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KUM59514.1 - 0.0011 19.0 0.1 0.0018 18.3 0.1 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family HlyIII PF03006.20 KUM59515.1 - 5.5e-57 193.1 10.0 6.1e-57 192.9 10.0 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF3325 PF11804.8 KUM59515.1 - 0.28 11.3 4.6 0.11 12.6 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3325) Zn_clus PF00172.18 KUM59516.1 - 9.9e-08 32.0 8.0 9.9e-08 32.0 8.0 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1749 PF08538.10 KUM59519.1 - 5.6e-104 347.4 0.0 6.4e-104 347.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF900 PF05990.12 KUM59519.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Glycos_transf_2 PF00535.26 KUM59520.1 - 2.5e-36 125.0 0.0 3e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KUM59520.1 - 7.5e-13 48.9 0.0 9.7e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KUM59520.1 - 9e-07 28.6 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KUM59520.1 - 0.00025 20.6 0.0 0.00048 19.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 KUM59520.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.6 KUM59520.1 - 0.16 12.5 0.0 0.35 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 FCH PF00611.23 KUM59521.1 - 1.8e-13 50.6 0.1 5e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KUM59521.1 - 1.5e-11 43.7 0.0 2.7e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KUM59521.1 - 1.4e-10 40.9 0.0 2.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KUM59521.1 - 1.6e-10 40.5 0.0 6.8e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain AAA_lid_2 PF17863.1 KUM59521.1 - 0.18 11.7 0.4 19 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA lid domain TMA7 PF09072.10 KUM59522.1 - 5.1e-22 78.5 23.7 5.7e-22 78.3 23.7 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Adeno_PV PF03910.13 KUM59522.1 - 0.029 13.1 1.6 0.031 13.0 1.6 1.0 1 0 0 1 1 1 0 Adenovirus minor core protein PV Pkinase PF00069.25 KUM59523.1 - 2.7e-52 177.7 0.0 3.6e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM59523.1 - 2.3e-23 82.8 0.0 6.5e-23 81.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RSRP PF17069.5 KUM59523.1 - 0.026 14.1 37.4 0.043 13.4 37.4 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Pox_ser-thr_kin PF05445.11 KUM59523.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cyt-b5 PF00173.28 KUM59524.1 - 7.2e-14 51.7 0.0 9.7e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DHR10 PF18595.1 KUM59525.1 - 0.13 12.3 1.4 0.25 11.4 1.4 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Ish1 PF10281.9 KUM59526.1 - 3.4e-82 270.4 18.9 3.5e-13 49.6 0.0 7.4 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KUM59526.1 - 5.9e-11 41.9 0.0 0.66 9.8 0.0 6.6 6 1 0 6 6 6 3 SAP domain HeH PF12949.7 KUM59526.1 - 8.6e-11 41.4 0.3 0.18 11.6 0.2 5.8 6 0 0 6 6 6 3 HeH/LEM domain ANAPC2 PF08672.11 KUM59526.1 - 2e-05 25.0 0.2 30 5.2 0.0 5.8 6 0 0 6 6 6 0 Anaphase promoting complex (APC) subunit 2 Thymopoietin PF08198.11 KUM59526.1 - 0.00043 19.8 0.0 0.23 11.1 0.0 3.6 4 0 0 4 4 4 1 Thymopoietin protein Slx4 PF09494.10 KUM59526.1 - 0.00078 19.3 1.4 21 5.1 0.0 5.4 6 0 0 6 6 6 0 Slx4 endonuclease LEM PF03020.15 KUM59526.1 - 0.0054 16.3 0.0 22 4.7 0.0 4.3 4 0 0 4 4 4 0 LEM domain CPSase_sm_chain PF00988.22 KUM59526.1 - 0.007 16.2 0.1 5.3 6.9 0.0 4.5 5 1 1 6 6 6 1 Carbamoyl-phosphate synthase small chain, CPSase domain SLATT_4 PF18186.1 KUM59526.1 - 0.053 13.2 0.9 0.16 11.6 0.9 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 DUF4224 PF13986.6 KUM59526.1 - 0.1 12.5 0.0 14 5.7 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4224) SAM_2 PF07647.17 KUM59526.1 - 0.21 11.7 4.6 34 4.6 0.1 5.1 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) Caudo_TAP PF02413.17 KUM59526.1 - 1.5 9.0 8.1 0.2 11.8 0.8 2.9 2 1 1 3 3 3 0 Caudovirales tail fibre assembly protein, lambda gpK YtxH PF12732.7 KUM59526.1 - 9.4 6.9 12.4 6.9 7.3 0.1 4.4 4 1 0 4 4 4 0 YtxH-like protein NTF2 PF02136.20 KUM59528.1 - 8.4e-23 81.2 0.1 9.7e-23 81.0 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 KUM59528.1 - 0.036 14.5 0.0 0.043 14.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) PQ-loop PF04193.14 KUM59529.1 - 1.1e-19 70.0 10.6 5.2e-12 45.4 2.6 3.7 4 1 1 5 5 5 2 PQ loop repeat Pkinase PF00069.25 KUM59530.1 - 2.7e-54 184.3 0.0 3.6e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM59530.1 - 6.7e-34 117.3 0.0 8.2e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM59530.1 - 9e-06 25.2 0.0 0.00071 19.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KUM59530.1 - 0.00011 22.2 0.0 0.0016 18.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KUM59530.1 - 0.02 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KUM59530.1 - 0.048 13.0 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KUM59530.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase UL11 PF11094.8 KUM59530.1 - 0.14 12.0 1.1 0.22 11.4 0.1 1.9 2 0 0 2 2 2 0 Membrane-associated tegument protein adh_short_C2 PF13561.6 KUM59531.1 - 2.8e-47 161.3 5.9 7.6e-39 133.7 6.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM59531.1 - 7e-44 149.6 5.4 8.7e-44 149.3 5.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM59531.1 - 8.5e-16 58.4 1.1 1.1e-15 58.0 1.1 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KUM59531.1 - 0.0008 19.3 1.3 0.0014 18.5 1.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KUM59531.1 - 0.011 14.9 0.1 0.016 14.4 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AdoHcyase_NAD PF00670.21 KUM59531.1 - 0.018 15.1 0.4 0.031 14.3 0.4 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KUM59531.1 - 0.066 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KUM59531.1 - 0.074 13.1 0.2 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Suf PF05843.14 KUM59532.1 - 6.3e-92 308.7 0.1 6.3e-92 308.7 0.1 4.8 5 2 0 5 5 5 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KUM59532.1 - 0.017 15.9 1.6 2.4 9.2 0.4 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat HAT PF02184.16 KUM59532.1 - 0.07 13.1 0.0 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat TPR_16 PF13432.6 KUM59532.1 - 0.079 13.6 4.0 0.1 13.2 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ASF1_hist_chap PF04729.13 KUM59533.1 - 5.1e-72 240.8 0.0 6.8e-72 240.4 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.12 KUM59533.1 - 0.012 13.9 22.7 0.015 13.5 22.7 1.0 1 0 0 1 1 1 0 Nop14-like family THUMP PF02926.17 KUM59536.1 - 8.1e-11 42.2 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 THUMP domain PAC1 PF16094.5 KUM59536.1 - 0.095 11.9 1.1 0.13 11.4 1.1 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 TPP_enzyme_N PF02776.18 KUM59537.1 - 6e-32 110.6 0.0 9.3e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KUM59537.1 - 3.8e-25 88.2 0.0 7.1e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KUM59537.1 - 2.2e-14 53.5 0.0 5.7e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KUM59537.1 - 0.044 12.7 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component Lgl_C PF08596.10 KUM59538.1 - 8.2e-132 439.6 0.0 4.6e-131 437.1 0.0 2.0 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KUM59538.1 - 2.1e-06 28.4 4.5 0.19 12.7 0.4 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM59538.1 - 3.3e-06 27.3 0.0 0.27 11.6 0.0 5.2 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M23 PF01551.22 KUM59538.1 - 0.031 14.5 0.0 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M23 Nup160 PF11715.8 KUM59538.1 - 0.055 12.1 0.0 6.4 5.3 0.0 3.0 3 0 0 3 3 3 0 Nucleoporin Nup120/160 APH PF01636.23 KUM59539.1 - 3.9e-09 36.8 0.1 6.9e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Piwi PF02171.17 KUM59540.1 - 8.3e-60 202.6 0.0 1.3e-59 201.9 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 KUM59540.1 - 4.6e-13 48.6 0.2 2.8e-12 46.1 0.0 2.3 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoN PF16486.5 KUM59540.1 - 4.4e-12 46.8 0.0 1.6e-11 45.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of argonaute PAZ PF02170.22 KUM59540.1 - 2.4e-11 43.6 0.5 5.2e-11 42.5 0.5 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KUM59540.1 - 8.8e-09 35.6 0.1 2.7e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 KUM59540.1 - 2.2e-08 34.3 0.0 5.6e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute PUF PF00806.19 KUM59541.1 - 1e-15 56.4 0.0 0.26 11.1 0.0 8.0 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat Sec34 PF04136.15 KUM59543.1 - 4.5e-50 169.4 1.6 8.9e-50 168.4 1.6 1.5 1 0 0 1 1 1 1 Sec34-like family HeLo PF14479.6 KUM59543.1 - 0.13 12.0 1.3 0.5 10.2 1.1 2.1 1 1 0 1 1 1 0 Prion-inhibition and propagation RCC1 PF00415.18 KUM59544.1 - 4.8e-32 110.3 1.9 6.5e-06 26.7 0.0 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KUM59544.1 - 8.9e-18 63.6 16.7 1.6e-11 43.7 0.1 6.7 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 KUM59544.1 - 0.00039 20.2 0.0 0.2 11.5 0.0 3.1 2 1 1 3 3 3 2 Peptidase family C25, C terminal ig-like domain Mcl1_mid PF12341.8 KUM59544.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region Abhydrolase_1 PF00561.20 KUM59545.1 - 2.1e-19 70.2 0.0 6.6e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KUM59545.1 - 2.4e-13 51.2 0.3 3.5e-13 50.7 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM59545.1 - 6.1e-09 35.5 0.0 2.4e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Pyridoxal_deC PF00282.19 KUM59546.1 - 1.3e-80 270.9 0.0 2.8e-80 269.8 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KUM59546.1 - 7.6e-05 21.8 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KUM59546.1 - 0.00012 21.5 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Collagen PF01391.18 KUM59546.1 - 0.0028 17.4 5.9 0.0061 16.3 5.9 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) MFS_1 PF07690.16 KUM59547.1 - 0.0016 17.4 1.7 0.0016 17.4 1.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.25 KUM59548.1 - 2.6e-61 207.3 0.0 1.8e-60 204.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM59548.1 - 5.2e-43 147.2 0.0 7.8e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM59548.1 - 5e-08 32.6 0.0 8.3e-07 28.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KUM59548.1 - 0.002 17.0 0.0 0.0052 15.6 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KUM59548.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KUM59548.1 - 0.021 14.8 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family SIR2 PF02146.17 KUM59549.1 - 3.6e-58 196.4 0.0 5.2e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KUM59549.1 - 0.038 13.7 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Pup PF05639.11 KUM59549.1 - 0.061 14.2 0.5 0.17 12.8 0.5 1.7 1 0 0 1 1 1 0 Pup-like protein COG4 PF08318.12 KUM59550.1 - 8.6e-126 419.5 0.0 1.5e-125 418.7 0.0 1.4 2 0 0 2 2 2 1 COG4 transport protein Cu-oxidase_3 PF07732.15 KUM59551.1 - 8e-38 129.1 3.0 8e-38 129.1 3.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KUM59551.1 - 2.1e-36 124.7 13.8 5.1e-36 123.4 0.7 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KUM59551.1 - 4.6e-36 124.3 0.7 1.4e-33 116.3 0.2 2.7 2 0 0 2 2 2 2 Multicopper oxidase JHD PF17811.1 KUM59552.1 - 8.6e-11 42.3 0.2 2.2e-10 41.0 0.2 1.7 1 0 0 1 1 1 1 Jumonji helical domain PHD PF00628.29 KUM59552.1 - 6.3e-09 35.6 6.1 6.3e-09 35.6 6.1 2.7 3 0 0 3 3 3 1 PHD-finger JmjC PF02373.22 KUM59552.1 - 7.8e-09 36.0 0.1 8.2e-08 32.7 0.1 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KUM59552.1 - 1.8e-08 34.4 0.0 4.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain PHD_2 PF13831.6 KUM59552.1 - 0.0022 17.5 4.7 0.0023 17.5 2.6 2.2 2 0 0 2 2 2 1 PHD-finger zinc_ribbon_10 PF10058.9 KUM59552.1 - 0.1 12.4 0.4 3.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein RRM_1 PF00076.22 KUM59553.1 - 1.1e-18 66.8 0.2 1.8e-18 66.1 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KUM59553.1 - 4e-06 26.4 0.0 4.8e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KUM59553.1 - 0.00094 19.0 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_8 PF11835.8 KUM59553.1 - 0.046 13.9 0.0 0.056 13.7 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain Strabismus PF06638.11 KUM59554.1 - 0.16 10.6 0.6 0.26 9.9 0.6 1.3 1 0 0 1 1 1 0 Strabismus protein APH PF01636.23 KUM59555.1 - 1.9e-24 86.9 0.0 2.5e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KUM59555.1 - 4.1e-05 23.3 0.0 7.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase YhfH PF14149.6 KUM59555.1 - 0.16 12.0 0.4 0.34 10.9 0.4 1.5 1 0 0 1 1 1 0 YhfH-like protein Hexokinase_2 PF03727.16 KUM59556.1 - 3.8e-79 265.5 0.0 5.6e-79 265.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KUM59556.1 - 1.2e-71 240.7 0.0 1.6e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase STIMATE PF12400.8 KUM59557.1 - 5.6e-40 136.8 5.2 5.6e-40 136.8 5.2 1.6 2 0 0 2 2 2 1 STIMATE family Zn_clus PF00172.18 KUM59558.1 - 0.0075 16.4 9.2 0.017 15.3 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.9 KUM59558.1 - 0.29 10.3 16.6 0.57 9.3 16.6 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Flavokinase PF01687.17 KUM59559.1 - 6.4e-32 110.2 0.0 9.1e-32 109.7 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase MFS_1 PF07690.16 KUM59560.1 - 6.2e-40 137.2 30.5 6.2e-40 137.2 30.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM59560.1 - 1.1e-09 37.7 9.2 1.1e-09 37.7 9.2 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KUM59560.1 - 5.6e-07 28.4 1.1 5.6e-07 28.4 1.1 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Bap31 PF05529.12 KUM59560.1 - 0.0004 20.2 0.0 0.0016 18.3 0.0 2.0 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region MFS_3 PF05977.13 KUM59560.1 - 0.0028 16.1 2.7 0.0041 15.6 2.7 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector E1-E2_ATPase PF00122.20 KUM59562.1 - 2.2e-47 160.9 0.3 6.7e-47 159.3 0.3 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KUM59562.1 - 4.4e-43 147.1 0.1 4.4e-43 147.1 0.1 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KUM59562.1 - 6e-20 72.4 0.2 4e-19 69.7 0.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KUM59562.1 - 7.3e-19 67.2 0.0 1.4e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KUM59562.1 - 1.1e-13 51.1 0.0 2.3e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KUM59562.1 - 0.00043 20.1 2.6 0.0007 19.4 1.1 2.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.13 KUM59563.1 - 2.3e-37 127.5 0.1 4.2e-37 126.7 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KUM59563.1 - 8.8e-08 31.3 0.5 2.3e-07 30.0 0.5 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Ammonium_transp PF00909.21 KUM59564.1 - 3.2e-114 381.8 28.6 3.6e-114 381.5 28.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SnoaL PF07366.12 KUM59566.1 - 0.0019 18.0 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Cu-oxidase_2 PF07731.14 KUM59568.1 - 2.4e-29 101.8 1.6 8.3e-26 90.4 0.7 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KUM59568.1 - 1.4e-15 57.3 0.1 6.9e-15 55.1 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KUM59568.1 - 3e-05 24.2 0.0 0.0057 16.8 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase GFO_IDH_MocA PF01408.22 KUM59569.1 - 2.2e-18 67.2 0.0 5.2e-18 66.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold ubiquitin PF00240.23 KUM59570.1 - 2.4e-33 113.7 0.7 3.3e-33 113.2 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 KUM59570.1 - 6.9e-30 102.7 11.2 1.1e-29 102.1 11.2 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 KUM59570.1 - 2.3e-15 56.2 0.9 3.3e-15 55.7 0.9 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KUM59570.1 - 6.1e-05 23.4 0.2 0.00021 21.7 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KUM59570.1 - 0.0022 18.3 0.2 0.0035 17.7 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KUM59570.1 - 0.0076 16.2 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KUM59570.1 - 0.021 14.9 0.0 0.041 14.0 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KUM59570.1 - 0.033 14.7 0.1 0.05 14.2 0.0 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KUM59570.1 - 0.064 13.3 1.1 11 6.1 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain Abhydrolase_1 PF00561.20 KUM59571.1 - 3.6e-19 69.4 0.0 4.4e-17 62.6 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM59571.1 - 9.9e-15 54.4 0.0 1.4e-13 50.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KUM59571.1 - 5.5e-12 46.8 12.5 5.6e-11 43.5 8.1 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 KUM59571.1 - 8.1e-05 22.1 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KUM59571.1 - 0.00019 21.1 0.0 0.00047 19.9 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KUM59571.1 - 0.017 14.0 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KUM59571.1 - 0.026 14.3 0.0 0.3 10.9 0.0 2.3 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KUM59571.1 - 0.09 12.6 0.0 0.72 9.7 0.0 2.3 3 0 0 3 3 3 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KUM59571.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase LIDHydrolase PF10230.9 KUM59571.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 KUM59571.1 - 0.2 11.4 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family RabGAP-TBC PF00566.18 KUM59572.1 - 3.1e-25 89.1 0.3 4.8e-25 88.5 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Yip1 PF04893.17 KUM59573.1 - 5e-15 55.6 16.0 6.6e-15 55.2 16.0 1.2 1 0 0 1 1 1 1 Yip1 domain SRP68 PF16969.5 KUM59574.1 - 4e-194 646.8 3.7 4.5e-194 646.6 3.7 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 p450 PF00067.22 KUM59575.1 - 1.5e-53 182.2 0.0 2e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rhodanese PF00581.20 KUM59576.1 - 5e-11 43.1 0.0 8.3e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain GTP_EFTU PF00009.27 KUM59577.1 - 2.8e-33 115.1 2.4 4.2e-33 114.5 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KUM59577.1 - 4.1e-19 68.7 0.1 1.6e-18 66.7 0.1 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KUM59577.1 - 3.2e-11 43.4 0.4 8.9e-10 38.8 0.0 3.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KUM59577.1 - 2.3e-08 33.8 0.2 7.1e-08 32.2 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 KUM59577.1 - 6.6e-07 29.4 0.1 9.6e-06 25.7 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KUM59577.1 - 0.00031 21.0 0.0 0.00091 19.4 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KUM59577.1 - 0.0011 18.8 0.0 0.0034 17.2 0.0 2.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.22 KUM59577.1 - 0.047 13.3 0.1 0.31 10.6 0.0 2.5 2 1 0 2 2 2 0 Ras family Mucin PF01456.17 KUM59577.1 - 1.5 8.8 6.5 0.22 11.5 1.1 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein TatD_DNase PF01026.21 KUM59579.1 - 4.2e-37 127.9 0.0 7.9e-37 127.0 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase PPR_2 PF13041.6 KUM59582.1 - 9.3e-19 67.4 1.8 5e-09 36.2 0.0 6.6 6 3 3 9 9 9 3 PPR repeat family PPR_3 PF13812.6 KUM59582.1 - 2.2e-16 59.7 0.0 1.2e-06 28.5 0.0 4.3 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.20 KUM59582.1 - 7.9e-14 50.8 2.0 0.14 12.5 0.0 8.3 10 0 0 10 10 10 4 PPR repeat PPR_1 PF12854.7 KUM59582.1 - 2.9e-09 36.5 0.2 0.47 10.2 0.0 5.7 6 0 0 6 6 6 3 PPR repeat PPR_long PF17177.4 KUM59582.1 - 8.5e-08 31.8 0.0 0.0047 16.3 0.0 2.7 2 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 KUM59582.1 - 0.055 13.3 0.0 2.7 7.9 0.0 3.4 3 1 0 3 3 3 0 Mitochondrial ATPase expression DUF4081 PF13312.6 KUM59582.1 - 0.099 12.8 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4081) MMS1_N PF10433.9 KUM59583.1 - 5.1e-89 299.1 0.0 1.3e-88 297.8 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KUM59583.1 - 6.6e-07 29.0 0.0 2.2e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region PQQ_3 PF13570.6 KUM59583.1 - 0.0034 17.8 1.1 7.7 7.2 0.1 4.0 3 0 0 3 3 3 2 PQQ-like domain MCM PF00493.23 KUM59585.1 - 3.5e-96 320.6 0.1 5.7e-96 319.9 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KUM59585.1 - 7.7e-31 106.6 0.0 2.8e-30 104.8 0.0 1.9 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 KUM59585.1 - 5.5e-24 84.4 0.5 1.2e-23 83.3 0.5 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KUM59585.1 - 1.7e-10 41.4 0.0 6.4e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KUM59585.1 - 4.5e-06 26.2 0.0 5e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KUM59585.1 - 0.0049 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TFIIF_alpha PF05793.12 KUM59585.1 - 3.4 6.2 11.7 4.9 5.6 11.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Spo7 PF03907.13 KUM59586.1 - 3.8e-88 294.7 0.0 5.7e-88 294.1 0.0 1.3 1 0 0 1 1 1 1 Spo7-like protein zf-RRN7 PF11781.8 KUM59587.1 - 1.2e-09 37.7 4.6 2.1e-09 36.9 4.6 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Fungal_trans PF04082.18 KUM59589.1 - 3.2e-21 75.5 0.0 8.9e-21 74.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM59589.1 - 4.8e-09 36.2 11.9 7.2e-09 35.6 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.18 KUM59590.1 - 4.6e-42 144.2 31.8 5.5e-42 143.9 31.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KUM59590.1 - 0.0026 16.8 18.5 0.0055 15.8 18.5 1.6 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF4134 PF13572.6 KUM59590.1 - 0.089 13.1 13.2 1.6 9.1 4.9 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4134) Tetraspanin PF00335.20 KUM59590.1 - 0.3 10.8 0.1 0.3 10.8 0.1 3.6 3 1 1 4 4 4 0 Tetraspanin family GWT1 PF06423.12 KUM59590.1 - 0.61 10.2 4.7 0.19 11.9 1.2 2.0 3 0 0 3 3 3 0 GWT1 Abhydrolase_9_N PF15420.6 KUM59590.1 - 8.1 6.4 10.0 1.6 8.7 3.0 2.6 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus LapA_dom PF06305.11 KUM59590.1 - 8.7 6.2 6.0 34 4.4 0.0 3.3 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Condensation PF00668.20 KUM59591.1 - 3.4e-30 105.1 0.0 4.6e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 KUM59592.1 - 1e-69 235.2 0.0 1.2e-69 234.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM59592.1 - 0.0095 16.9 0.1 0.025 15.5 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain VMA21 PF09446.10 KUM59593.1 - 0.09 12.9 0.2 0.11 12.6 0.2 1.1 1 0 0 1 1 1 0 VMA21-like domain BATS PF06968.13 KUM59594.1 - 7.4e-22 77.3 0.2 3.3e-21 75.2 0.0 2.1 2 1 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KUM59594.1 - 4.3e-16 59.8 0.0 4.7e-15 56.4 0.1 2.1 2 0 0 2 2 2 1 Radical SAM superfamily AMP-binding PF00501.28 KUM59595.1 - 1.9e-73 247.5 0.0 2.4e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM59595.1 - 1.1e-05 26.3 0.0 2.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_4 PF01565.23 KUM59597.1 - 4.4e-22 78.3 2.7 1.5e-21 76.6 2.7 2.0 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KUM59597.1 - 5.2e-12 45.7 0.9 1.2e-11 44.5 0.9 1.7 1 0 0 1 1 1 1 Berberine and berberine like Sugar_tr PF00083.24 KUM59598.1 - 5.6e-91 305.7 22.7 6.7e-91 305.4 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM59598.1 - 2.3e-33 115.6 45.3 1.6e-28 99.7 24.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM59598.1 - 1.7e-05 23.5 0.7 3.3e-05 22.5 0.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KUM59598.1 - 0.00011 21.6 4.2 0.00011 21.6 4.2 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Transferase PF02458.15 KUM59602.1 - 1.4e-22 80.0 0.0 2.3e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Transferase family Citrate_synt PF00285.21 KUM59603.1 - 1.8e-95 320.1 0.0 2.2e-95 319.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain ABC_tran PF00005.27 KUM59604.1 - 1.8e-47 161.3 0.0 8.1e-26 91.2 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KUM59604.1 - 3.1e-15 56.8 3.9 2.4e-05 24.3 0.0 4.2 2 2 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KUM59604.1 - 3.2e-11 43.1 0.2 0.0029 17.1 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KUM59604.1 - 3.7e-07 30.8 0.2 0.017 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KUM59604.1 - 2.3e-06 27.6 0.0 0.049 13.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Chromo PF00385.24 KUM59604.1 - 3.8e-06 26.7 0.1 7.3e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.6 KUM59604.1 - 6.3e-06 25.8 1.5 0.063 13.0 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KUM59604.1 - 3.7e-05 23.7 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 KUM59604.1 - 0.00011 22.4 0.0 0.19 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KUM59604.1 - 0.00037 20.7 1.7 0.28 11.2 0.4 3.2 4 0 0 4 4 2 1 Helicase HerA, central domain NACHT PF05729.12 KUM59604.1 - 0.00043 20.2 0.1 0.093 12.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 KUM59604.1 - 0.00043 20.1 0.2 0.52 10.0 0.4 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KUM59604.1 - 0.0012 19.1 0.1 0.21 11.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KUM59604.1 - 0.0022 18.2 0.0 1.2 9.5 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MeaB PF03308.16 KUM59604.1 - 0.0026 16.8 0.2 0.94 8.4 0.1 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 KUM59604.1 - 0.005 17.2 0.1 1.2 9.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.23 KUM59604.1 - 0.0054 16.8 0.0 0.42 10.7 0.0 3.0 4 0 0 4 4 3 1 Dynamin family DNA_ligase_OB_2 PF14743.6 KUM59604.1 - 0.0054 16.7 0.3 0.015 15.3 0.3 1.8 1 0 0 1 1 1 1 DNA ligase OB-like domain AAA_33 PF13671.6 KUM59604.1 - 0.011 15.9 0.1 3 8.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KUM59604.1 - 0.012 15.4 0.1 1.3 8.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KUM59604.1 - 0.021 15.4 0.0 9.4 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KUM59604.1 - 0.022 14.5 0.5 7.5 6.2 0.2 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KUM59604.1 - 0.027 14.9 0.0 1.1 9.6 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KUM59604.1 - 0.027 13.6 0.0 3.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 KUM59604.1 - 0.042 13.6 0.0 7.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.6 KUM59604.1 - 0.048 12.3 0.0 2.1 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KUM59604.1 - 0.096 11.9 0.0 13 5.0 0.0 2.2 2 0 0 2 2 2 0 Septin ALF PF03752.13 KUM59604.1 - 0.11 12.5 6.9 5.1 7.2 0.3 3.9 3 0 0 3 3 3 0 Short repeats of unknown function Zeta_toxin PF06414.12 KUM59604.1 - 0.11 11.7 0.2 11 5.2 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin CLP1_P PF16575.5 KUM59604.1 - 0.11 12.2 2.1 17 5.1 0.0 3.4 4 0 0 4 4 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 KUM59604.1 - 0.15 11.2 0.4 0.66 9.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain TsaE PF02367.17 KUM59604.1 - 0.16 12.0 0.7 23 5.0 0.1 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 KUM59604.1 - 0.19 12.0 0.0 33 4.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MukB PF04310.12 KUM59604.1 - 0.21 11.4 0.4 24 4.7 0.1 2.3 2 0 0 2 2 2 0 MukB N-terminal HEAT_EZ PF13513.6 KUM59604.1 - 0.23 12.0 0.6 3.8 8.1 0.1 3.3 3 0 0 3 3 2 0 HEAT-like repeat AAA_27 PF13514.6 KUM59604.1 - 0.31 10.6 2.1 8.6 5.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain Goodbye PF17109.5 KUM59605.1 - 4.4e-36 124.0 1.2 7.9e-36 123.2 0.0 2.1 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain AAA_16 PF13191.6 KUM59605.1 - 2.1e-05 25.0 0.0 8.1e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain TPR_6 PF13174.6 KUM59605.1 - 0.00099 19.6 1.6 16 6.4 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KUM59605.1 - 0.0021 18.5 3.1 0.17 12.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.6 KUM59605.1 - 0.0036 17.6 0.4 0.029 14.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain TPR_12 PF13424.6 KUM59605.1 - 0.035 14.4 3.9 0.17 12.2 0.3 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KUM59605.1 - 0.12 13.2 6.5 0.6 11.1 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat NACHT PF05729.12 KUM59605.1 - 0.13 12.2 0.2 0.7 9.8 0.2 2.3 1 1 0 1 1 1 0 NACHT domain C1_2 PF03107.16 KUM59605.1 - 0.33 11.3 6.8 2.7 8.4 1.8 2.5 2 0 0 2 2 2 0 C1 domain HypA PF01155.19 KUM59605.1 - 1.6 8.8 4.0 27 4.8 0.2 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RNA_POL_M_15KD PF02150.16 KUM59605.1 - 1.7 8.6 3.8 1.6 8.7 0.3 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit FA_hydroxylase PF04116.13 KUM59606.1 - 7.8e-23 81.3 14.9 7.8e-23 81.3 14.9 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TMF_TATA_bd PF12325.8 KUM59609.1 - 0.0004 20.6 1.3 1.3 9.3 1.7 2.5 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding EzrA PF06160.12 KUM59609.1 - 0.0014 16.9 4.0 0.0014 16.9 4.0 1.4 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA Spc7 PF08317.11 KUM59609.1 - 0.0017 17.3 4.2 0.0034 16.3 4.2 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein IFT57 PF10498.9 KUM59609.1 - 0.0071 15.4 2.6 0.013 14.5 2.6 1.4 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 V-SNARE PF05008.15 KUM59609.1 - 0.017 15.5 2.4 0.071 13.5 2.4 2.1 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Rop-like PF05082.13 KUM59609.1 - 0.034 13.9 0.7 0.092 12.6 0.7 1.7 1 0 0 1 1 1 0 Rop-like DUF1664 PF07889.12 KUM59609.1 - 0.053 13.6 9.2 0.08 13.0 2.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) GldM_C PF12080.8 KUM59609.1 - 0.059 13.6 0.1 0.059 13.6 0.1 1.9 2 0 0 2 2 1 0 GldM C-terminal domain Atg14 PF10186.9 KUM59609.1 - 0.071 12.2 3.6 0.18 10.9 3.6 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 KUM59609.1 - 0.08 13.0 0.2 0.08 13.0 0.2 2.5 3 0 0 3 3 3 0 Laminin Domain II DUF2353 PF09789.9 KUM59609.1 - 0.11 11.8 13.5 0.15 11.4 5.2 2.4 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) TMPIT PF07851.13 KUM59609.1 - 0.12 11.6 5.1 0.037 13.3 2.0 1.6 1 1 0 1 1 1 0 TMPIT-like protein NPV_P10 PF05531.12 KUM59609.1 - 0.18 12.3 10.7 0.61 10.6 0.6 3.1 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.8 KUM59609.1 - 0.23 10.7 6.3 2.4 7.4 5.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 KUM59609.1 - 0.28 11.4 3.6 0.94 9.8 0.8 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Mod_r PF07200.13 KUM59609.1 - 0.3 11.2 3.4 0.9 9.6 2.6 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein LPP PF04728.13 KUM59609.1 - 0.44 11.0 5.4 5.4 7.5 0.1 3.2 2 1 1 3 3 2 0 Lipoprotein leucine-zipper DUF4763 PF15960.5 KUM59609.1 - 0.5 9.6 7.0 0.031 13.6 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) SKA1 PF07160.12 KUM59609.1 - 0.61 9.9 8.1 0.15 11.9 1.6 2.8 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Syntaxin-6_N PF09177.11 KUM59609.1 - 1.2 9.7 4.6 3 8.4 1.4 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 KUM59609.1 - 1.4 8.2 5.5 2.1 7.6 5.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 KUM59609.1 - 2.4 6.0 5.4 3.5 5.4 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.6 KUM59609.1 - 2.5 7.4 9.2 3.3 7.0 2.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 KUM59609.1 - 3.5 7.8 13.5 2.8 8.1 4.4 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 KUM59609.1 - 4.2 7.7 9.8 0.26 11.5 1.4 2.8 3 0 0 3 3 3 0 Haemolysin XhlA FlaC_arch PF05377.11 KUM59609.1 - 4.2 7.8 5.2 11 6.5 0.8 3.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 KUM59609.1 - 5.4 7.4 9.2 10 6.5 1.3 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.9 KUM59609.1 - 5.7 7.7 6.8 1.7 9.4 2.4 2.2 2 1 1 3 3 2 0 Uncharacterized conserved protein (DUF2203) DUF16 PF01519.16 KUM59609.1 - 8 7.0 14.2 6.3 7.4 6.8 2.9 1 1 2 3 3 3 0 Protein of unknown function DUF16 NOC3p PF07540.11 KUM59610.1 - 2.6e-31 107.9 0.3 2.6e-31 107.9 0.3 2.2 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 KUM59610.1 - 6.9e-26 91.3 1.9 1.6e-25 90.1 0.2 2.3 2 0 0 2 2 2 1 CBF/Mak21 family DUF1349 PF07081.11 KUM59612.1 - 6.4e-23 81.4 0.0 7.7e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) ATP-synt_C PF00137.21 KUM59613.1 - 6.9e-09 35.9 13.6 1.3e-08 35.1 13.6 1.5 1 0 0 1 1 1 1 ATP synthase subunit C FIN1 PF17300.2 KUM59613.1 - 0.017 14.6 0.1 0.02 14.4 0.1 1.1 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 Sulfate_transp PF00916.20 KUM59614.1 - 1.6e-84 283.9 17.9 3.3e-58 197.3 9.7 2.2 1 1 1 2 2 2 2 Sulfate permease family STAS PF01740.21 KUM59614.1 - 5.5e-09 35.7 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.10 KUM59614.1 - 0.042 13.8 4.6 0.059 13.3 2.0 2.8 2 0 0 2 2 2 0 Stannin transmembrane UPF0113 PF03657.13 KUM59615.1 - 6.1e-23 80.9 0.0 7.6e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 KUM59615.1 - 2.7e-06 27.3 0.0 3.5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 PUA domain UPF0113_N PF17833.1 KUM59615.1 - 0.24 12.0 0.3 0.37 11.4 0.3 1.3 1 0 0 1 1 1 0 UPF0113 Pre-PUA domain Cullin_binding PF03556.15 KUM59616.1 - 1.9e-32 112.2 1.7 2.1e-32 112.1 1.7 1.0 1 0 0 1 1 1 1 Cullin binding Toxin_YhaV PF11663.8 KUM59616.1 - 0.014 15.5 0.1 0.021 14.9 0.1 1.4 1 0 0 1 1 1 0 Toxin with endonuclease activity, of toxin-antitoxin system Cript PF10235.9 KUM59617.1 - 5.6e-25 87.7 9.5 5.6e-25 87.7 9.5 1.8 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 KUM59617.1 - 0.0069 16.4 15.1 0.039 14.0 8.7 2.6 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_15 PF17032.5 KUM59617.1 - 0.0098 16.6 11.3 0.016 15.9 7.7 2.6 2 1 0 2 2 2 1 zinc-ribbon family CEBP_ZZ PF16366.5 KUM59617.1 - 0.041 14.1 4.1 0.041 14.1 4.1 1.9 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain AAA_29 PF13555.6 KUM59617.1 - 0.17 11.7 1.1 20 5.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KUM59617.1 - 0.26 11.8 3.3 2.4 8.7 0.9 2.2 1 1 1 2 2 2 0 ABC transporter NinF PF05810.12 KUM59617.1 - 0.34 10.8 5.5 6.6 6.7 0.0 2.9 2 1 1 3 3 3 0 NinF protein zf-BED PF02892.15 KUM59617.1 - 0.61 10.2 5.4 5.6 7.1 2.5 2.5 2 1 0 2 2 2 0 BED zinc finger zinc_ribbon_2 PF13240.6 KUM59617.1 - 1.1 9.1 13.9 7.7 6.4 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Prim_Zn_Ribbon PF08273.12 KUM59617.1 - 6 7.2 11.7 38 4.7 0.0 4.0 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF2039 PF10217.9 KUM59617.1 - 6.6 7.1 18.5 2.5 8.5 12.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) MRP-L46 PF11788.8 KUM59618.1 - 3.5e-38 131.0 1.2 6.8e-38 130.1 1.2 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KUM59618.1 - 0.00027 21.0 0.0 0.00054 20.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain CAF1 PF04857.20 KUM59619.1 - 8.6e-76 255.1 0.0 1e-75 254.9 0.0 1.0 1 0 0 1 1 1 1 CAF1 family ribonuclease adh_short PF00106.25 KUM59621.1 - 1.4e-49 168.2 1.0 1.8e-49 167.9 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM59621.1 - 4.8e-37 127.8 0.5 6e-37 127.4 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM59621.1 - 5.8e-14 52.4 0.2 8.3e-14 51.9 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KUM59621.1 - 7.4e-05 22.0 0.2 0.00011 21.4 0.2 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KUM59621.1 - 0.00034 20.2 1.6 0.0015 18.1 0.6 2.2 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KUM59621.1 - 0.00079 19.4 0.4 0.0015 18.5 0.4 1.5 1 1 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 KUM59621.1 - 0.037 14.0 0.1 0.15 12.0 0.1 1.9 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 KUM59621.1 - 0.038 14.1 0.1 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HEM4 PF02602.15 KUM59621.1 - 0.05 13.0 0.1 0.092 12.1 0.1 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Hanta_nucleocap PF00846.18 KUM59622.1 - 0.12 10.9 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein Golgin_A5 PF09787.9 KUM59622.1 - 0.38 10.2 9.6 1.1 8.7 2.1 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 SBF_like PF13593.6 KUM59623.1 - 1.4e-91 307.1 18.5 1.7e-91 306.8 18.5 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.18 KUM59623.1 - 0.011 14.1 0.0 0.011 14.1 0.0 2.8 2 1 1 3 3 3 0 Membrane transport protein Mito_carr PF00153.27 KUM59624.1 - 2.5e-65 216.4 3.3 1.3e-22 79.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3224 PF11528.8 KUM59625.1 - 0.0082 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3224) Mpv17_PMP22 PF04117.12 KUM59626.1 - 1.1e-12 48.0 0.8 1.6e-11 44.3 0.7 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family Dynamin_N PF00350.23 KUM59629.1 - 1.8e-25 89.9 0.1 9e-23 81.2 0.0 3.1 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KUM59629.1 - 1.6e-19 70.2 0.9 5.1e-16 58.7 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 KUM59629.1 - 0.0004 20.5 0.1 0.0011 19.0 0.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KUM59629.1 - 0.00064 19.8 0.1 0.017 15.2 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase IIGP PF05049.13 KUM59629.1 - 0.03 13.4 0.1 5.2 6.0 0.0 2.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_15 PF13175.6 KUM59629.1 - 0.038 13.7 2.0 1.8 8.2 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 KUM59629.1 - 0.044 14.0 0.1 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NAAA-beta PF15508.6 KUM59629.1 - 0.051 13.9 0.1 1.7 9.0 0.0 3.4 4 0 0 4 4 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Arc_C PF18162.1 KUM59629.1 - 0.058 13.3 0.1 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Arc C-lobe AAA_16 PF13191.6 KUM59629.1 - 0.47 10.8 2.5 1.8 8.9 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain tRNA-synt_2 PF00152.20 KUM59630.1 - 8.5e-60 202.5 0.5 3.8e-34 118.2 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KUM59630.1 - 3.7e-12 46.1 0.0 1.1e-11 44.6 0.1 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF3512 PF12024.8 KUM59630.1 - 0.084 12.3 0.3 0.15 11.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) ChAPs PF09295.10 KUM59630.1 - 0.087 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) zf-C3HC4_2 PF13923.6 KUM59631.1 - 0.15 11.9 3.5 0.27 11.1 3.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 KUM59631.1 - 0.18 12.0 4.5 0.3 11.3 4.5 1.3 1 0 0 1 1 1 0 B-box zinc finger zf-4CXXC_R1 PF10497.9 KUM59631.1 - 0.2 11.9 6.3 0.38 11.0 6.3 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C3HC4_3 PF13920.6 KUM59631.1 - 0.23 11.3 5.9 0.35 10.8 5.9 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) COX15-CtaA PF02628.15 KUM59632.1 - 2.7e-114 381.6 3.5 3.3e-114 381.3 3.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein zf-C3HC PF07967.13 KUM59633.1 - 5.6e-40 136.4 0.5 8.1e-37 126.2 0.1 2.4 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 KUM59633.1 - 4.3e-35 119.7 1.8 1.3e-32 111.8 0.0 2.9 3 0 0 3 3 3 2 Rsm1-like Mod_r PF07200.13 KUM59634.1 - 0.0045 17.1 0.1 0.0064 16.6 0.1 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Nrap_D5 PF17406.2 KUM59635.1 - 0.025 14.4 0.1 0.036 13.8 0.1 1.2 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 Abhydrolase_3 PF07859.13 KUM59637.1 - 6.4e-39 134.0 0.0 9.2e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KUM59637.1 - 1.7e-11 43.7 0.0 3.9e-11 42.5 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KUM59637.1 - 0.0005 19.0 0.0 0.00068 18.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF2974 PF11187.8 KUM59637.1 - 0.21 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PEPCK_ATP PF01293.20 KUM59638.1 - 1.3e-214 713.2 0.0 1.5e-214 713.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 KUM59638.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 KUM59640.1 - 3.5e-12 45.9 25.0 8.3e-12 44.7 25.0 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KUM59640.1 - 1.1e-07 31.8 5.1 1.1e-07 31.8 5.1 2.8 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 Mito_carr PF00153.27 KUM59641.1 - 1.4e-55 185.1 3.0 4.8e-18 64.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-Nse PF11789.8 KUM59642.1 - 5e-23 80.7 1.4 1.1e-22 79.6 1.4 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KUM59642.1 - 0.0015 18.5 0.1 0.0049 16.9 0.0 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-MIZ PF02891.20 KUM59642.1 - 0.016 14.9 3.2 0.081 12.7 3.2 2.0 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.6 KUM59642.1 - 0.034 14.0 1.4 0.081 12.8 0.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KUM59642.1 - 0.12 12.7 0.3 0.22 11.9 0.3 1.5 1 0 0 1 1 1 0 Ring finger domain Pox_MCEL PF03291.16 KUM59643.1 - 4.4e-67 226.5 0.0 6.5e-43 147.1 0.0 3.2 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 KUM59643.1 - 6.6e-09 36.4 0.0 0.0024 18.5 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KUM59643.1 - 1.7e-07 31.9 0.0 9.1e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM59643.1 - 3.6e-06 27.5 0.0 0.023 15.4 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KUM59643.1 - 0.00014 21.6 0.0 0.0034 17.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM59643.1 - 0.0003 20.7 0.0 0.00063 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KUM59643.1 - 0.01 15.1 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family SWIRM-assoc_2 PF16496.5 KUM59643.1 - 5.5 5.8 7.0 9.4 5.0 7.0 1.4 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal YqzH PF14164.6 KUM59644.1 - 1.4 9.0 3.8 24 5.1 0.6 2.5 2 0 0 2 2 2 0 YqzH-like protein DUF1765 PF08578.10 KUM59646.1 - 1.1e-44 151.9 7.3 1.1e-44 151.9 7.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) TPP_enzyme_N PF02776.18 KUM59647.1 - 3.4e-34 117.9 0.0 5.5e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KUM59647.1 - 7.4e-18 64.6 0.0 1.8e-17 63.4 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KUM59647.1 - 3.9e-15 56.0 0.2 1.3e-13 51.0 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DIL PF01843.19 KUM59649.1 - 2.4e-30 104.8 1.3 2.4e-30 104.8 1.3 1.8 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.7 KUM59649.1 - 1.1e-13 51.6 0.0 3.4e-13 50.0 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KUM59649.1 - 9.6e-09 35.3 0.0 0.0008 19.7 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KUM59649.1 - 1.6e-07 31.4 0.0 0.041 14.3 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KUM59649.1 - 6.5e-07 29.8 0.0 0.0057 17.2 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM59649.1 - 7.6e-06 25.9 0.1 0.015 15.8 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat DUF3349 PF11829.8 KUM59649.1 - 0.0078 17.0 0.5 0.022 15.5 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3349) TFIIB PF00382.19 KUM59650.1 - 1.1e-39 134.2 0.2 8.9e-20 70.5 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KUM59650.1 - 6.5e-11 41.6 1.1 6.5e-11 41.6 1.1 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.23 KUM59650.1 - 0.00048 19.9 0.1 0.72 9.6 0.1 2.3 1 1 1 2 2 2 2 Cyclin, N-terminal domain RB_B PF01857.20 KUM59650.1 - 0.0028 17.7 0.0 0.0054 16.8 0.0 1.5 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 KUM59650.1 - 0.035 14.2 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Cyclin, C-terminal domain TMIE PF16038.5 KUM59650.1 - 0.11 12.4 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 TMIE protein Sigma70_r4_2 PF08281.12 KUM59650.1 - 0.19 11.4 0.0 0.57 9.9 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4 PF04545.16 KUM59650.1 - 0.2 11.2 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 DUF1610 PF07754.11 KUM59650.1 - 0.36 10.8 2.6 1.2 9.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-ribbon_3 PF13248.6 KUM59650.1 - 6.3 6.3 8.1 6.2 6.4 3.5 2.6 2 1 0 2 2 2 0 zinc-ribbon domain ATP_sub_h PF10775.9 KUM59651.1 - 3.3e-29 100.7 1.8 4.7e-29 100.2 1.8 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 KUM59651.1 - 0.014 15.8 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Zn_clus PF00172.18 KUM59652.1 - 0.00035 20.6 11.8 0.00051 20.1 7.8 2.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM59652.1 - 0.00047 19.3 0.0 0.001 18.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ERAP1_C PF11838.8 KUM59652.1 - 0.0035 16.9 0.0 0.0086 15.7 0.0 1.6 1 0 0 1 1 1 1 ERAP1-like C-terminal domain RasGEF PF00617.19 KUM59653.1 - 7.6e-43 146.8 0.4 1.5e-42 145.8 0.4 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KUM59653.1 - 3.3e-13 49.8 1.0 9.2e-13 48.3 1.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Peptidase_M13_N PF05649.13 KUM59654.1 - 1e-92 311.8 0.0 1.5e-92 311.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KUM59654.1 - 4.2e-61 206.1 0.1 6.9e-61 205.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 FMN_dh PF01070.18 KUM59656.1 - 3.7e-117 391.2 0.0 4.3e-117 391.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KUM59656.1 - 1e-06 28.2 0.0 2.5e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 KUM59656.1 - 2.6e-06 26.7 1.9 2.7e-05 23.4 0.1 2.7 3 1 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KUM59656.1 - 0.001 18.6 0.1 0.12 11.8 0.0 2.5 1 1 1 2 2 2 2 Histidine biosynthesis protein DHO_dh PF01180.21 KUM59656.1 - 0.063 12.5 0.2 0.84 8.8 0.0 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase ThiG PF05690.14 KUM59656.1 - 0.078 12.3 0.3 2.2 7.6 0.0 2.5 2 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG PHP PF02811.19 KUM59656.1 - 0.093 13.0 0.0 11 6.2 0.0 2.3 2 0 0 2 2 2 0 PHP domain CutC PF03932.14 KUM59656.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 CutC family HMG_CoA_synt_C PF08540.10 KUM59658.1 - 2.1e-106 355.6 0.6 2.7e-106 355.3 0.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KUM59658.1 - 1.1e-95 318.5 0.3 2e-95 317.6 0.3 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal TFR_dimer PF04253.15 KUM59659.1 - 1.1e-36 125.5 0.0 2.1e-36 124.6 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KUM59659.1 - 4.7e-20 72.1 0.0 9.8e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KUM59659.1 - 1.5e-12 47.3 0.0 2.7e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KUM59659.1 - 0.08 12.6 0.0 0.2 11.3 0.0 1.7 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KUM59659.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Nicastrin DUF364 PF04016.12 KUM59660.1 - 0.036 13.7 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative heavy-metal chelation Fungal_trans PF04082.18 KUM59665.1 - 4.7e-12 45.5 0.1 1.2e-11 44.2 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM59665.1 - 1.3e-05 25.3 9.2 2.5e-05 24.3 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3597 PF12200.8 KUM59665.1 - 0.069 13.7 0.2 0.28 11.7 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3597) Peptidase_M19 PF01244.21 KUM59666.1 - 2.5e-100 335.7 0.0 3e-100 335.5 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Smg4_UPF3 PF03467.15 KUM59667.1 - 4.3e-43 147.3 0.0 4.3e-43 147.3 0.0 2.6 2 1 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.22 KUM59667.1 - 1.6e-06 27.8 0.0 6.6e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_3 PF01494.19 KUM59668.1 - 1.9e-79 267.4 0.0 2.4e-79 267.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KUM59668.1 - 1e-46 159.0 0.0 1.7e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 KUM59668.1 - 0.00025 20.3 0.1 0.00058 19.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KUM59668.1 - 0.00035 20.8 0.1 0.0011 19.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KUM59668.1 - 0.00051 19.4 0.0 0.0009 18.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 KUM59668.1 - 0.0025 17.2 0.0 0.81 8.9 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.24 KUM59668.1 - 0.0029 17.3 0.3 0.013 15.2 0.1 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM59668.1 - 0.0094 15.2 0.0 0.02 14.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KUM59668.1 - 0.038 13.4 0.2 0.057 12.8 0.2 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.10 KUM59668.1 - 0.041 12.9 0.0 0.17 10.9 0.0 1.8 1 1 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.14 KUM59668.1 - 0.044 12.6 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 KUM59668.1 - 0.083 13.5 0.0 0.32 11.6 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KUM59668.1 - 0.1 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans_2 PF11951.8 KUM59669.1 - 0.01 14.7 0.7 0.01 14.7 0.7 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lactonase PF10282.9 KUM59670.1 - 5e-19 68.8 0.0 7e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Metallophos PF00149.28 KUM59671.1 - 0.022 15.3 0.0 0.033 14.7 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Metallophos PF00149.28 KUM59672.1 - 3.8e-10 40.6 0.0 5.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UPF0239 PF06783.11 KUM59673.1 - 4.2 7.6 10.0 5.1 7.3 10.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Glyco_hydro_7 PF00840.20 KUM59674.1 - 5.3e-211 700.9 13.0 5.3e-211 700.9 13.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KUM59674.1 - 2.4e-11 43.4 12.6 2.4e-11 43.4 12.6 4.1 4 1 0 4 4 4 1 Fungal cellulose binding domain Sporozoite_P67 PF05642.11 KUM59674.1 - 0.68 7.9 10.0 1 7.4 10.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cellulase PF00150.18 KUM59675.1 - 5e-46 157.4 1.9 6.5e-46 157.0 1.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KUM59675.1 - 1.4e-11 44.1 9.7 1.4e-11 44.1 9.7 3.2 3 0 0 3 3 3 1 Fungal cellulose binding domain MFS_1 PF07690.16 KUM59676.1 - 9.6e-15 54.4 19.3 1.2e-13 50.7 19.8 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily Peptidase_M20 PF01546.28 KUM59677.1 - 8.7e-05 22.3 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Sua5_yciO_yrdC PF01300.18 KUM59678.1 - 3e-09 36.6 0.0 4.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination HalOD1 PF18545.1 KUM59678.1 - 0.014 15.7 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 Halobacterial output domain 1 Peptidase_A4 PF01828.17 KUM59679.1 - 1.4e-72 243.6 9.2 1.7e-72 243.3 9.2 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF2753 PF10952.8 KUM59680.1 - 0.038 14.1 0.0 0.041 14.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) RNA_pol_Rpb4 PF03874.16 KUM59680.1 - 0.078 13.3 0.0 0.084 13.2 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb4 M20_dimer PF07687.14 KUM59682.1 - 0.00013 21.8 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M35 PF02102.15 KUM59684.1 - 2.9e-174 579.1 15.9 3.2e-174 578.9 15.9 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KUM59684.1 - 3.6e-38 131.4 7.2 3.6e-38 131.4 7.2 1.9 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase CARDB PF07705.11 KUM59684.1 - 0.011 16.0 0.0 0.041 14.1 0.0 2.0 1 1 0 1 1 1 0 CARDB HMGL-like PF00682.19 KUM59684.1 - 0.058 12.9 0.1 0.097 12.2 0.1 1.4 1 0 0 1 1 1 0 HMGL-like DUF5314 PF17241.2 KUM59684.1 - 0.16 11.6 0.2 0.35 10.5 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5314) Methyltransf_23 PF13489.6 KUM59686.1 - 3.1e-10 40.1 0.0 4.2e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM59686.1 - 1.3e-07 32.2 0.0 4.3e-07 30.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM59686.1 - 0.00013 21.8 0.0 0.0014 18.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM59686.1 - 0.00021 22.0 0.0 0.0031 18.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM59686.1 - 0.00096 19.8 0.0 0.002 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KUM59686.1 - 0.0028 17.2 0.0 0.0065 16.0 0.0 1.5 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 KUM59686.1 - 0.0074 15.8 0.2 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KUM59686.1 - 0.1 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Transp_cyt_pur PF02133.15 KUM59687.1 - 3.5e-81 273.2 25.0 5.6e-77 259.4 16.3 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1485 PF07364.12 KUM59688.1 - 9.3e-103 343.4 0.2 1.2e-102 343.1 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M81 MlrC_C PF07171.12 KUM59688.1 - 5.7e-57 192.8 0.0 8.6e-57 192.2 0.0 1.3 1 0 0 1 1 1 1 MlrC C-terminus Formyl_trans_N PF00551.19 KUM59689.1 - 2.8e-40 138.0 0.2 3.6e-40 137.6 0.2 1.1 1 0 0 1 1 1 1 Formyl transferase ACT_6 PF13740.6 KUM59689.1 - 6e-08 32.6 0.3 7.2e-07 29.1 0.0 2.8 2 2 1 3 3 3 1 ACT domain ACT PF01842.25 KUM59689.1 - 8.3e-07 28.7 0.0 3.8e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 ACT domain NUDIX PF00293.28 KUM59690.1 - 6.3e-08 32.7 0.0 7.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Abhydrolase_6 PF12697.7 KUM59691.1 - 4.7e-11 43.7 0.3 4.7e-11 43.7 0.3 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM59691.1 - 2.3e-10 40.6 0.0 8.8e-10 38.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM59691.1 - 2.9e-07 30.0 0.0 9.4e-07 28.3 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KUM59691.1 - 7.7e-06 24.8 0.0 1.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 KUM59691.1 - 0.012 15.2 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative esterase CMD PF02627.20 KUM59692.1 - 3.9e-08 33.2 0.1 3.7e-07 30.1 0.1 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family bZIP_1 PF00170.21 KUM59693.1 - 1.9e-10 40.7 10.5 1.1e-08 35.0 9.0 2.7 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KUM59693.1 - 0.02 15.0 12.0 0.44 10.7 7.4 3.0 2 1 1 3 3 3 0 Basic region leucine zipper BLOC1_2 PF10046.9 KUM59693.1 - 0.022 15.0 0.6 0.041 14.2 0.6 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CCDC85 PF10226.9 KUM59693.1 - 0.044 13.5 0.7 0.14 11.8 0.1 1.9 2 0 0 2 2 2 0 CCDC85 family Imm32 PF15566.6 KUM59693.1 - 0.12 12.2 0.2 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 32 DUF2205 PF10224.9 KUM59693.1 - 0.31 11.1 2.5 0.55 10.3 2.5 1.4 1 0 0 1 1 1 0 Short coiled-coil protein PRKG1_interact PF15898.5 KUM59693.1 - 0.45 11.4 4.7 0.37 11.7 2.0 2.1 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain M20_dimer PF07687.14 KUM59694.1 - 6.4e-09 35.7 0.1 2.1e-08 34.0 0.0 1.9 2 1 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KUM59694.1 - 3.3e-07 30.2 0.2 5.4e-07 29.5 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Fungal_trans_2 PF11951.8 KUM59695.1 - 2.1e-50 171.6 3.6 2.6e-50 171.4 3.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Antimicrobial_9 PF08104.11 KUM59695.1 - 0.28 11.2 0.2 0.86 9.7 0.2 1.8 1 0 0 1 1 1 0 Ponericin L family DIOX_N PF14226.6 KUM59696.1 - 1.8e-21 77.1 0.0 2.8e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KUM59696.1 - 7e-13 48.9 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fructosamin_kin PF03881.14 KUM59696.1 - 0.072 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase FAD_binding_3 PF01494.19 KUM59700.1 - 1.2e-23 84.0 0.0 1.5e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KUM59700.1 - 3.7e-05 23.5 1.8 0.00062 19.4 1.1 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM59700.1 - 4.8e-05 22.7 0.4 0.00092 18.5 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM59700.1 - 9.1e-05 21.7 2.1 0.0011 18.1 0.7 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KUM59700.1 - 9.4e-05 22.9 0.1 0.0011 19.5 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KUM59700.1 - 0.009 14.9 0.7 7.2 5.3 0.2 3.0 3 0 0 3 3 3 2 Tryptophan halogenase FAD_oxidored PF12831.7 KUM59700.1 - 0.011 15.1 0.3 0.017 14.5 0.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KUM59700.1 - 0.05 13.9 0.3 0.14 12.4 0.3 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain peroxidase PF00141.23 KUM59701.1 - 5.1e-80 268.4 0.0 2.5e-42 145.1 0.0 2.3 2 0 0 2 2 2 2 Peroxidase MFS_1 PF07690.16 KUM59702.1 - 2.6e-25 89.1 34.3 2.6e-25 89.1 34.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KUM59702.1 - 6.6e-05 22.4 3.8 6.6e-05 22.4 3.8 2.2 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB P5CR_dimer PF14748.6 KUM59704.1 - 3.4e-35 120.4 1.3 4.1e-35 120.1 0.5 1.6 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KUM59704.1 - 8.1e-17 61.6 0.2 1.8e-16 60.5 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KUM59704.1 - 0.02 14.6 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KUM59704.1 - 0.021 14.8 0.2 0.075 13.0 0.2 1.9 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus zinc_ribbon_10 PF10058.9 KUM59705.1 - 8.9e-20 70.2 0.3 1.4e-19 69.5 0.3 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Ribonuclease_3 PF00636.26 KUM59706.1 - 2.7e-40 137.2 0.0 2.1e-22 79.7 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KUM59706.1 - 3.9e-29 101.4 0.0 1.3e-13 51.3 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KUM59706.1 - 2.7e-23 81.9 0.0 8.1e-23 80.4 0.0 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 KUM59706.1 - 1.2e-17 64.3 0.0 6.6e-16 58.6 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM59706.1 - 7.1e-16 58.5 0.1 2.9e-15 56.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM59706.1 - 1.8e-12 47.6 0.0 4.7e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KUM59706.1 - 0.081 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein UvrD-helicase PF00580.21 KUM59706.1 - 0.2 11.2 0.5 0.79 9.2 0.0 2.0 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DMT_6 PF04342.12 KUM59707.1 - 0.091 13.0 0.4 6.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Putative member of DMT superfamily (DUF486) DUF1686 PF07937.11 KUM59709.1 - 0.011 15.6 0.6 0.018 14.9 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) GMC_oxred_N PF00732.19 KUM59710.1 - 5.4e-55 186.8 0.0 7.3e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM59710.1 - 1e-32 113.7 0.1 1.8e-32 112.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KUM59710.1 - 2.7e-07 30.5 0.2 0.00049 19.8 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KUM59710.1 - 3.2e-07 29.7 0.0 5.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KUM59710.1 - 3.9e-05 23.1 0.1 0.092 12.0 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM59710.1 - 6.2e-05 23.1 0.1 0.00017 21.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM59710.1 - 0.00023 20.5 0.0 0.0016 17.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KUM59710.1 - 0.0011 18.2 0.1 0.7 8.9 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A CBM_11 PF03425.13 KUM59710.1 - 0.002 18.1 0.4 0.0056 16.6 0.1 1.7 1 1 0 1 1 1 1 Carbohydrate binding domain (family 11) FAD_binding_2 PF00890.24 KUM59710.1 - 0.0031 16.7 0.9 0.017 14.2 0.1 2.3 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KUM59710.1 - 0.0071 15.1 0.0 0.071 11.8 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KUM59710.1 - 0.0078 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Gal-bind_lectin PF00337.22 KUM59710.1 - 0.18 11.3 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Galactoside-binding lectin Fungal_trans PF04082.18 KUM59713.1 - 1.8e-14 53.4 2.4 2.2e-14 53.1 0.2 2.1 2 1 1 3 3 3 1 Fungal specific transcription factor domain ECH_1 PF00378.20 KUM59714.1 - 1e-43 149.5 0.0 1.6e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HMGL-like PF00682.19 KUM59714.1 - 1e-41 143.3 0.0 1.4e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 HMGL-like ECH_2 PF16113.5 KUM59714.1 - 4.9e-22 78.9 0.1 7.1e-22 78.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 KUM59715.1 - 1.3e-92 310.6 0.0 1.5e-92 310.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM59715.1 - 7.8e-15 55.6 0.0 4.7e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KUM59716.1 - 7.3e-33 113.9 24.0 9.7e-33 113.5 23.3 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KUM59716.1 - 9.6e-06 25.1 11.7 8.6e-05 22.0 11.7 2.0 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Ribosomal_L19 PF01245.20 KUM59717.1 - 9.5e-16 57.7 1.7 1.7e-15 56.9 1.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 PriA_3primeBD PF17764.1 KUM59717.1 - 0.12 12.2 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 3′ DNA-binding domain (3′BD) AMP-binding PF00501.28 KUM59719.1 - 1.9e-12 46.5 0.2 5.8e-07 28.4 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme NPCC PF08058.11 KUM59720.1 - 4.8e-25 88.1 0.0 7.2e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex component CytochromB561_N PF09786.9 KUM59720.1 - 0.00072 18.7 2.0 0.00087 18.4 2.0 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal Hid1 PF12722.7 KUM59721.1 - 0 1109.5 0.0 0 1109.3 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KUM59721.1 - 5.3e-99 332.4 0.0 6.2e-99 332.1 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein CPSase_L_D2 PF02786.17 KUM59722.1 - 1.1e-70 237.5 0.1 1.7e-70 236.8 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KUM59722.1 - 3.1e-41 140.4 0.2 8.4e-41 139.0 0.1 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KUM59722.1 - 2.3e-30 104.9 0.0 4.6e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KUM59722.1 - 1.7e-11 43.8 1.3 4.4e-11 42.4 1.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KUM59722.1 - 7.5e-10 38.7 0.3 1.7e-09 37.5 0.3 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KUM59722.1 - 1.9e-08 34.1 0.2 4.8e-08 32.8 0.2 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KUM59722.1 - 3.4e-07 30.4 0.0 5.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 KUM59722.1 - 0.0078 15.5 0.0 3 7.0 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp Biotin_lipoyl_2 PF13533.6 KUM59722.1 - 0.026 14.3 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Biotin-lipoyl like ATPgrasp_ST PF14397.6 KUM59722.1 - 0.072 12.3 0.0 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp O_Spanin_T7 PF17531.2 KUM59723.1 - 0.024 14.6 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 outer-membrane spanin sub-unit ABC2_membrane PF01061.24 KUM59724.1 - 2.5e-81 272.1 57.6 3.9e-42 144.1 15.0 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KUM59724.1 - 4.6e-35 121.1 0.0 2.7e-17 63.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KUM59724.1 - 1.4e-26 92.3 0.7 1.1e-20 73.4 0.0 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KUM59724.1 - 7.3e-14 52.2 0.1 2.5e-13 50.4 0.1 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KUM59724.1 - 4.9e-05 23.8 0.1 0.024 15.0 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KUM59724.1 - 5e-05 23.3 0.0 0.031 14.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KUM59724.1 - 5.8e-05 23.6 0.0 0.0018 18.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain ABC2_membrane_3 PF12698.7 KUM59724.1 - 9.4e-05 21.7 45.5 0.0099 15.0 12.3 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.6 KUM59724.1 - 0.00055 20.1 0.0 0.013 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KUM59724.1 - 0.00091 18.8 0.2 0.0079 15.8 0.1 2.4 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KUM59724.1 - 0.001 19.0 0.1 0.0031 17.4 0.0 1.8 2 0 0 2 2 1 1 RsgA GTPase AAA_29 PF13555.6 KUM59724.1 - 0.0011 18.7 0.3 0.011 15.4 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KUM59724.1 - 0.013 15.8 0.1 0.077 13.2 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KUM59724.1 - 0.035 14.4 0.1 0.57 10.5 0.0 3.0 4 0 0 4 4 3 0 AAA domain SMC_N PF02463.19 KUM59724.1 - 0.049 13.1 0.0 2.6 7.4 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 KUM59724.1 - 0.071 13.5 0.0 0.7 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KUM59724.1 - 0.087 12.5 1.0 2.3 7.9 0.2 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KUM59724.1 - 0.097 12.2 1.5 0.29 10.7 0.6 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MbeD_MobD PF04899.12 KUM59724.1 - 0.15 12.2 0.2 0.32 11.1 0.2 1.6 1 0 0 1 1 1 0 MbeD/MobD like NACHT PF05729.12 KUM59724.1 - 0.15 12.0 0.5 7.2 6.5 0.2 2.4 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 KUM59724.1 - 0.33 11.4 0.1 0.33 11.4 0.1 3.1 4 0 0 4 4 3 0 AAA domain SIMPL PF04402.14 KUM59725.1 - 4.5e-27 95.8 0.0 5.2e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Thioredoxin PF00085.20 KUM59726.1 - 1.5e-26 92.4 0.2 1.8e-26 92.1 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KUM59726.1 - 6.2e-07 29.7 0.0 8.7e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KUM59726.1 - 5.7e-06 26.8 0.1 0.00011 22.6 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KUM59726.1 - 7.6e-05 22.6 0.0 9.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KUM59726.1 - 0.00014 21.6 0.2 0.00089 19.0 0.1 1.9 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 KUM59726.1 - 0.0018 18.4 0.3 0.0055 16.9 0.3 1.9 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KUM59726.1 - 0.0018 17.7 0.3 0.003 17.0 0.0 1.5 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family TraF PF13728.6 KUM59726.1 - 0.003 17.4 0.1 0.0035 17.2 0.1 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 KUM59726.1 - 0.0035 17.1 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_5 PF13743.6 KUM59726.1 - 0.02 14.6 0.1 0.14 11.8 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Phosducin PF02114.16 KUM59726.1 - 0.036 13.0 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosducin Thioredoxin_4 PF13462.6 KUM59726.1 - 0.082 13.1 0.6 22 5.2 0.1 2.8 1 1 2 3 3 3 0 Thioredoxin DSBA PF01323.20 KUM59726.1 - 0.091 12.5 0.4 2.4 7.9 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Glutaredoxin PF00462.24 KUM59726.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Carboxyl_trans PF01039.22 KUM59727.1 - 1.3e-114 383.5 0.0 1.7e-114 383.2 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain HAT_KAT11 PF08214.11 KUM59729.1 - 6e-107 358.0 0.0 8.7e-107 357.4 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein DUF2738 PF10927.8 KUM59729.1 - 0.087 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) Ank_4 PF13637.6 KUM59730.1 - 5.2e-15 55.6 0.6 8.5e-09 35.8 0.1 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KUM59730.1 - 3.4e-14 53.2 0.2 2.6e-13 50.4 0.3 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KUM59730.1 - 9e-13 48.1 1.5 4e-08 33.4 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KUM59730.1 - 8e-11 42.0 1.6 5.4e-09 36.2 0.8 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM59730.1 - 2.7e-09 36.5 0.0 2.3e-06 27.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Glyco_transf_21 PF13506.6 KUM59731.1 - 7.6e-14 51.6 0.2 3e-06 26.8 0.0 3.4 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KUM59731.1 - 2.1e-05 24.5 0.0 4.4e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KUM59731.1 - 0.0068 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Mito_carr PF00153.27 KUM59732.1 - 1.7e-56 188.1 0.5 6.1e-20 70.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_1 PF00441.24 KUM59733.1 - 5.7e-30 104.5 1.2 9.2e-30 103.8 1.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KUM59733.1 - 2.3e-24 86.2 0.0 8.5e-23 81.2 0.0 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KUM59733.1 - 3.8e-23 81.5 0.1 6.4e-23 80.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KUM59733.1 - 0.0011 19.3 0.5 0.0015 18.8 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DAGAT PF03982.13 KUM59733.1 - 0.073 12.0 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Diacylglycerol acyltransferase DEAD PF00270.29 KUM59734.1 - 5.3e-47 159.8 0.0 1e-46 158.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM59734.1 - 2e-23 82.8 0.0 7.2e-23 81.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KUM59734.1 - 8.7e-22 77.2 2.4 2.8e-21 75.5 2.4 2.0 1 0 0 1 1 1 1 DBP10CT (NUC160) domain RPA_C PF08784.11 KUM59735.1 - 1.3e-21 77.2 0.2 3.8e-21 75.7 0.0 1.9 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KUM59735.1 - 0.00028 20.8 0.3 0.00074 19.5 0.3 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain MatE PF01554.18 KUM59736.1 - 1e-58 197.5 26.1 8.3e-35 119.8 9.3 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KUM59736.1 - 1.2e-05 25.4 9.8 1.2e-05 25.4 9.8 3.7 3 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF202 PF02656.15 KUM59737.1 - 2.1e-17 63.3 3.6 3.5e-17 62.6 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF716 PF04819.12 KUM59737.1 - 0.073 12.7 1.4 0.33 10.6 1.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF716) NUDIX PF00293.28 KUM59738.1 - 3e-26 92.0 0.0 4.4e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain tRNA-synt_2e PF02091.15 KUM59738.1 - 0.045 13.0 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit TauD PF02668.16 KUM59739.1 - 1.1e-60 205.7 0.3 1.4e-60 205.4 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FMO-like PF00743.19 KUM59740.1 - 4.7e-36 124.3 0.0 5.8e-21 74.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KUM59740.1 - 1.8e-16 60.2 0.0 3.2e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM59740.1 - 4.1e-15 55.8 0.8 4.1e-11 42.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM59740.1 - 3e-10 40.3 0.4 1.6e-07 31.5 0.4 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KUM59740.1 - 2e-08 34.2 4.2 9.1e-05 22.2 3.3 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 KUM59740.1 - 2.1e-07 30.4 1.8 0.00011 21.5 0.0 3.1 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KUM59740.1 - 4.1e-07 30.1 0.5 1.9e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KUM59740.1 - 2.9e-06 27.8 1.9 0.00072 20.1 0.5 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KUM59740.1 - 4.4e-06 26.4 0.1 0.029 14.0 0.0 3.8 3 1 1 4 4 4 1 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.24 KUM59740.1 - 3.4e-05 23.3 0.2 0.034 13.5 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KUM59740.1 - 0.0021 17.4 1.5 0.0035 16.7 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KUM59740.1 - 0.0047 16.3 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KUM59740.1 - 0.0082 16.2 1.3 0.047 13.8 0.4 2.4 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KUM59740.1 - 0.013 14.2 2.0 0.028 13.1 2.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 KUM59740.1 - 0.018 14.3 1.5 0.031 13.5 0.7 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 KUM59740.1 - 0.035 13.2 0.0 0.075 12.1 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain NAD_binding_2 PF03446.15 KUM59740.1 - 0.038 14.2 0.0 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KUM59740.1 - 0.081 12.8 2.5 0.14 12.0 2.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KUM59740.1 - 0.14 11.4 4.1 0.53 9.5 2.8 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KUM59740.1 - 1.3 8.0 2.7 2.3 7.2 2.7 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Swi3 PF07962.12 KUM59741.1 - 0.021 14.8 0.0 0.027 14.4 0.0 1.1 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 Ost4 PF10215.9 KUM59742.1 - 4.5e-19 68.0 2.2 5.7e-19 67.7 2.2 1.1 1 0 0 1 1 1 1 Oligosaccaryltransferase Zn_clus PF00172.18 KUM59743.1 - 3.9e-10 39.7 9.5 6e-10 39.1 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM59743.1 - 2.9e-09 36.3 0.0 4.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RabGAP-TBC PF00566.18 KUM59745.1 - 2.4e-42 145.0 0.0 3.3e-40 138.0 0.0 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain adh_short_C2 PF13561.6 KUM59746.1 - 5.8e-54 183.1 1.2 7.3e-54 182.8 1.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM59746.1 - 4.6e-44 150.2 0.5 6e-44 149.8 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM59746.1 - 6.7e-08 32.6 0.4 2.5e-07 30.8 0.4 1.8 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 KUM59746.1 - 0.14 12.9 0.0 0.31 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DENN PF02141.21 KUM59747.1 - 6.9e-40 137.0 0.1 1.3e-39 136.1 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KUM59747.1 - 1.4e-05 25.8 0.1 8.5e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.11 KUM59747.1 - 0.2 12.2 9.2 0.044 14.3 4.3 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A CENP-F_leu_zip PF10473.9 KUM59747.1 - 0.34 10.9 15.9 0.051 13.6 6.1 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cnn_1N PF07989.11 KUM59747.1 - 3.3 7.9 14.0 0.24 11.6 2.4 3.1 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 GldM_N PF12081.8 KUM59747.1 - 4.7 7.3 10.9 0.45 10.6 4.6 2.2 1 1 1 2 2 2 0 GldM N-terminal domain Pkinase PF00069.25 KUM59748.1 - 6.2e-22 78.2 0.0 9.1e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 KUM59748.1 - 1.1e-10 40.9 3.6 0.25 11.7 0.0 6.9 6 0 0 6 6 6 2 HEAT repeat WD40 PF00400.32 KUM59748.1 - 1.4e-06 28.9 14.7 4.2e-06 27.4 0.1 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT_2 PF13646.6 KUM59748.1 - 0.00036 20.9 2.5 3.7 8.0 0.0 4.5 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KUM59748.1 - 0.00041 20.8 0.4 0.022 15.3 0.2 3.5 3 0 0 3 3 3 1 HEAT-like repeat Pkinase_Tyr PF07714.17 KUM59748.1 - 0.00062 19.1 0.0 0.0012 18.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Tti2 PF10521.9 KUM59748.1 - 0.013 15.1 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 Tti2 family Cnd1 PF12717.7 KUM59748.1 - 0.06 13.4 0.6 0.96 9.5 0.0 2.5 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Ge1_WD40 PF16529.5 KUM59748.1 - 0.06 12.3 0.5 0.64 8.9 0.0 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Dexa_ind PF15198.6 KUM59750.1 - 8.6 6.5 9.1 0.19 11.9 0.8 2.5 3 0 0 3 3 3 0 Dexamethasone-induced zf-C2H2 PF00096.26 KUM59751.1 - 3.7e-09 36.5 11.4 2.1e-05 24.7 2.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM59751.1 - 1.8e-06 28.3 9.9 0.0045 17.7 1.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KUM59751.1 - 0.0025 18.1 5.6 0.82 10.1 0.8 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KUM59751.1 - 0.023 15.0 5.9 0.047 14.0 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KUM59751.1 - 0.029 14.7 4.6 0.044 14.1 4.6 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KUM59751.1 - 0.036 14.5 14.9 2.2 8.8 9.3 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-LYAR PF08790.11 KUM59751.1 - 0.8 9.7 4.7 0.64 10.0 0.4 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 KUM59751.1 - 1.3 9.4 7.2 4.9 7.5 0.9 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KUM59751.1 - 1.6 8.9 7.5 2.5 8.2 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Nsp1_C PF05064.13 KUM59752.1 - 0.025 14.4 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region Chorismate_bind PF00425.18 KUM59754.1 - 8.7e-64 215.6 0.0 2.4e-61 207.6 0.0 2.8 2 1 0 2 2 2 1 chorismate binding enzyme GATase PF00117.28 KUM59754.1 - 1.3e-29 103.4 0.0 2.1e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KUM59754.1 - 1.1e-09 38.7 0.0 2.8e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KUM59754.1 - 0.00014 21.7 0.0 0.00042 20.1 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 COesterase PF00135.28 KUM59755.1 - 1.7e-63 215.3 0.0 2.1e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KUM59755.1 - 1.8e-08 34.5 0.0 0.001 19.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold ISAV_HA PF06215.11 KUM59755.1 - 0.046 12.9 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin Zn_clus PF00172.18 KUM59756.1 - 9.8e-07 28.8 7.3 9.8e-07 28.8 7.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Actin PF00022.19 KUM59757.1 - 2.9e-132 441.2 0.0 1.3e-131 439.0 0.0 1.7 1 1 0 1 1 1 1 Actin Pet127 PF08634.10 KUM59758.1 - 1.5e-119 398.4 2.5 2.4e-119 397.8 2.5 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 GARS_A PF01071.19 KUM59759.1 - 7.1e-82 273.9 0.0 1.1e-81 273.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KUM59759.1 - 1.3e-33 115.6 0.1 5e-33 113.7 0.0 2.1 2 0 0 2 2 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 KUM59759.1 - 2.4e-33 115.5 0.0 5.1e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 KUM59759.1 - 2.2e-26 91.9 0.3 5.7e-26 90.6 0.3 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KUM59759.1 - 2.3e-14 53.8 3.2 4.4e-14 52.9 1.9 2.2 2 0 0 2 2 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_2 PF08442.10 KUM59759.1 - 0.00024 20.7 0.1 0.0012 18.4 0.0 2.1 3 0 0 3 3 3 1 ATP-grasp domain ATP-grasp PF02222.22 KUM59759.1 - 0.00038 20.1 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KUM59759.1 - 0.0011 19.0 0.1 0.004 17.2 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KUM59759.1 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 KUM59759.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 KUM59759.1 - 0.11 11.8 0.0 0.55 9.4 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp LRR_6 PF13516.6 KUM59760.1 - 0.025 14.6 5.3 1.1e+02 3.3 0.0 6.5 7 0 0 7 7 7 0 Leucine Rich repeat TRAPPC9-Trs120 PF08626.11 KUM59761.1 - 0 1508.8 0.0 0 1508.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 KUM59761.1 - 0.1 12.9 0.3 0.24 11.7 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Fes1 PF08609.10 KUM59762.1 - 1.4e-30 106.0 0.6 1.4e-30 106.0 0.6 2.0 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 Arm PF00514.23 KUM59762.1 - 1.6e-07 31.1 0.0 0.0014 18.6 0.0 2.5 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KUM59762.1 - 2.4e-07 31.1 0.3 1e-06 29.0 0.3 2.0 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.6 KUM59762.1 - 7.2e-07 29.6 0.3 2.1e-05 24.9 0.1 2.5 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.22 KUM59762.1 - 0.00017 21.6 0.0 0.029 14.6 0.0 2.7 2 0 0 2 2 2 1 HEAT repeat Atx10homo_assoc PF09759.9 KUM59762.1 - 0.00098 19.1 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_C PF11698.8 KUM59762.1 - 0.0011 19.0 0.2 0.035 14.2 0.1 1.9 1 1 1 2 2 2 2 V-ATPase subunit H CTNNBL PF08216.11 KUM59762.1 - 0.0015 18.7 0.3 0.048 13.8 0.1 2.3 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear SIL1 PF16782.5 KUM59762.1 - 0.0055 16.0 0.4 0.59 9.3 0.1 2.1 1 1 1 2 2 2 2 Nucleotide exchange factor SIL1 Aldedh PF00171.22 KUM59763.1 - 1.8e-129 432.3 0.0 2e-129 432.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Med6 PF04934.14 KUM59764.1 - 9.6e-39 132.2 0.1 1.3e-38 131.8 0.1 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component Lysine_decarbox PF03641.14 KUM59765.1 - 3.2e-27 95.2 0.0 5.2e-27 94.5 0.0 1.3 1 1 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KUM59765.1 - 0.38 10.3 2.7 0.52 9.9 0.5 2.1 2 0 0 2 2 2 0 SLOG cluster4 family DUF3684 PF12449.8 KUM59766.1 - 0 1421.3 0.0 0 1421.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KUM59766.1 - 0.00034 20.4 0.0 0.00086 19.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pheromone PF08015.11 KUM59766.1 - 2.5 9.2 5.6 2.8 9.0 1.5 3.4 2 0 0 2 2 2 0 Fungal mating-type pheromone WLM PF08325.10 KUM59766.1 - 3.3 7.8 5.6 0.5 10.4 0.5 2.0 2 0 0 2 2 2 0 WLM domain Sld7_C PF18596.1 KUM59767.1 - 4e-16 58.9 0.0 7.3e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Sld7 C-terminal domain UPF0220 PF05255.11 KUM59768.1 - 2.5e-71 238.6 2.6 2.8e-71 238.4 2.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF998 PF06197.13 KUM59768.1 - 9.5e-06 25.3 5.9 1.1e-05 25.1 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF998) ATP1G1_PLM_MAT8 PF02038.16 KUM59768.1 - 0.02 14.3 1.0 0.041 13.3 0.1 2.0 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Proteasome PF00227.26 KUM59769.1 - 9.1e-50 168.8 0.1 1.1e-49 168.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KUM59769.1 - 1.3e-12 47.2 0.4 2e-12 46.6 0.4 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.14 KUM59770.1 - 2.1e-45 153.5 6.2 2.3e-45 153.3 6.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4231 PF14015.6 KUM59770.1 - 0.17 12.4 1.2 4.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF4349 PF14257.6 KUM59770.1 - 0.25 10.7 0.0 0.25 10.7 0.0 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) Exo_endo_phos PF03372.23 KUM59771.1 - 0.0019 17.7 0.2 0.0041 16.7 0.2 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3915 PF13054.6 KUM59772.1 - 0.033 14.2 0.4 0.033 14.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 KUM59772.1 - 5.2 5.2 4.8 5.3 5.2 4.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family PEX11 PF05648.14 KUM59773.1 - 5.6e-76 254.9 0.2 6.3e-76 254.7 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) TBPIP PF07106.13 KUM59773.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain Arch_fla_DE PF04659.13 KUM59773.1 - 0.11 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Archaeal flagella protein RPN7 PF10602.9 KUM59774.1 - 6.7e-53 179.0 0.2 1.1e-52 178.3 0.2 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KUM59774.1 - 3.4e-15 56.4 0.0 7.4e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain Sugar_tr PF00083.24 KUM59775.1 - 3.4e-28 98.7 31.0 2.7e-19 69.4 11.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KUM59775.1 - 2.7e-16 59.4 40.7 6.4e-15 54.9 39.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_membrane PF00664.23 KUM59775.1 - 0.23 11.1 6.9 1.6 8.3 1.6 2.8 2 0 0 2 2 2 0 ABC transporter transmembrane region PDR_CDR PF06422.12 KUM59775.1 - 4.4 7.3 7.6 8.7 6.3 0.1 3.6 3 0 0 3 3 3 0 CDR ABC transporter Fungal_trans PF04082.18 KUM59776.1 - 2.8e-15 56.1 0.1 4.3e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM59776.1 - 7.5e-08 32.4 11.6 8.2e-08 32.2 7.8 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPE65 PF03055.15 KUM59777.1 - 7.8e-113 378.1 0.0 8.8e-113 377.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein ACT_3 PF10000.9 KUM59778.1 - 1.7e-18 66.3 0.2 2.6e-18 65.7 0.2 1.3 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 KUM59778.1 - 6e-10 38.8 0.0 1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 KUM59778.1 - 0.027 14.2 0.0 0.61 9.9 0.0 2.5 2 0 0 2 2 2 0 ACT domain Zn_clus PF00172.18 KUM59780.1 - 2.8e-10 40.1 8.2 4.6e-10 39.5 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IL34 PF15036.6 KUM59780.1 - 0.11 12.6 0.1 3 7.9 0.0 2.3 2 0 0 2 2 2 0 Interleukin 34 GFA PF04828.14 KUM59784.1 - 1.8e-18 66.7 0.1 1.8e-18 66.7 0.1 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PALP PF00291.25 KUM59785.1 - 1.2e-61 208.7 0.2 1.4e-61 208.5 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PG_isomerase_N PF18353.1 KUM59785.1 - 0.039 14.4 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucose isomerase N-terminal domain PAD_porph PF04371.15 KUM59786.1 - 3.5e-89 299.2 0.0 4.1e-89 299.0 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Pcc1 PF09341.10 KUM59786.1 - 0.037 14.1 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Transcription factor Pcc1 Copper-fist PF00649.18 KUM59787.1 - 3.6e-21 74.4 3.7 3.6e-21 74.4 3.7 2.3 2 1 1 3 3 3 1 Copper fist DNA binding domain Aminotran_1_2 PF00155.21 KUM59788.1 - 4.4e-39 134.7 0.0 6.1e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II zf_ZIC PF18366.1 KUM59789.1 - 0.001 19.1 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 Zic proteins zinc finger domain RFX_DNA_binding PF02257.15 KUM59789.1 - 0.013 16.2 0.0 0.026 15.2 0.0 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain SspK PF08176.12 KUM59789.1 - 0.017 15.3 0.0 0.071 13.4 0.0 2.1 2 0 0 2 2 2 0 Small acid-soluble spore protein K family DUF2682 PF10909.8 KUM59789.1 - 0.16 12.4 0.0 0.47 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2682) His_Phos_2 PF00328.22 KUM59790.1 - 6.1e-12 45.6 0.0 7.3e-10 38.7 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Rep_fac_C PF08542.11 KUM59791.1 - 2.6e-17 63.0 0.0 1e-16 61.1 0.0 2.0 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 KUM59791.1 - 2.2e-16 60.5 0.0 4e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KUM59791.1 - 6.8e-13 48.7 0.2 1.9e-12 47.3 0.0 1.9 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KUM59791.1 - 2.4e-08 34.1 0.0 4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KUM59791.1 - 1.1e-06 28.9 0.0 4.2e-06 27.0 0.0 2.1 2 1 0 2 2 1 1 AAA C-terminal domain AAA_30 PF13604.6 KUM59791.1 - 1.3e-06 28.3 0.2 3e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KUM59791.1 - 1.7e-06 28.4 0.1 1.5e-05 25.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KUM59791.1 - 2e-06 28.3 0.1 4.8e-05 23.8 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 KUM59791.1 - 4.1e-06 26.8 0.1 6.7e-05 22.8 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KUM59791.1 - 2.8e-05 24.1 0.6 0.00011 22.2 0.1 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KUM59791.1 - 5.9e-05 22.9 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KUM59791.1 - 7e-05 22.1 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KUM59791.1 - 0.00013 21.8 0.0 0.00032 20.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 KUM59791.1 - 0.00013 21.7 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 KUM59791.1 - 0.00026 20.9 0.2 0.0023 17.8 0.1 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KUM59791.1 - 0.00026 21.3 0.1 0.00091 19.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KUM59791.1 - 0.00051 19.5 0.5 0.72 9.3 0.0 2.5 1 1 1 2 2 2 2 PhoH-like protein AAA_14 PF13173.6 KUM59791.1 - 0.00063 19.8 0.0 0.0014 18.6 0.0 1.6 1 1 1 2 2 1 1 AAA domain DEAD PF00270.29 KUM59791.1 - 0.0047 16.7 0.1 0.045 13.5 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase TniB PF05621.11 KUM59791.1 - 0.0061 16.0 0.1 0.052 12.9 0.1 2.2 1 1 0 1 1 1 1 Bacterial TniB protein Sigma54_activat PF00158.26 KUM59791.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.6 KUM59791.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KUM59791.1 - 0.013 15.5 0.0 0.17 11.8 0.0 2.1 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 KUM59791.1 - 0.017 15.7 0.0 0.027 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KUM59791.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 KUM59791.1 - 0.029 13.6 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KUM59791.1 - 0.042 13.4 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KUM59791.1 - 0.044 13.2 0.2 0.26 10.6 0.1 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KUM59791.1 - 0.044 14.2 0.0 0.16 12.4 0.0 1.9 1 1 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KUM59791.1 - 0.078 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KUM59791.1 - 0.093 13.2 0.0 0.18 12.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter TIP49 PF06068.13 KUM59791.1 - 0.14 11.4 0.0 0.44 9.7 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain Pro_isomerase PF00160.21 KUM59792.1 - 4.4e-39 134.3 0.0 7.5e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 KUM59792.1 - 0.0043 17.5 0.1 0.0043 17.5 0.1 3.3 2 1 0 3 3 3 1 Domain of unknown function (DUF4604) MCPVI PF02993.14 KUM59792.1 - 3.1 7.6 6.4 7.6 6.3 6.4 1.6 1 0 0 1 1 1 0 Minor capsid protein VI Clr5 PF14420.6 KUM59793.1 - 1.5e-09 38.0 0.4 1.9e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Clr5 domain HTH_Tnp_Tc3_2 PF01498.18 KUM59793.1 - 1e-05 25.7 1.8 0.0016 18.6 0.6 2.2 2 0 0 2 2 2 2 Transposase HTH_12 PF08461.10 KUM59793.1 - 0.003 17.5 1.8 0.79 9.7 0.1 2.3 1 1 0 2 2 2 2 Ribonuclease R winged-helix domain HTH_32 PF13565.6 KUM59793.1 - 0.008 16.8 0.3 0.24 12.0 0.0 2.2 1 1 1 2 2 2 1 Homeodomain-like domain Terminase_5 PF06056.12 KUM59793.1 - 0.025 14.5 0.2 0.08 12.8 0.2 1.8 1 1 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) DDE_Tnp_ISAZ013 PF07592.11 KUM59793.1 - 0.066 12.2 2.2 1 8.2 0.4 2.0 1 1 1 2 2 2 0 Rhodopirellula transposase DDE domain Aldo_ket_red PF00248.21 KUM59794.1 - 7.6e-12 45.0 0.0 3.2e-11 43.0 0.0 1.8 1 1 0 2 2 2 1 Aldo/keto reductase family HSF_DNA-bind PF00447.17 KUM59795.1 - 1.4e-28 99.4 0.2 2.8e-28 98.4 0.2 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 KUM59795.1 - 0.067 13.7 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Ets-domain TMF_DNA_bd PF12329.8 KUM59795.1 - 0.18 11.9 1.2 2.1 8.4 0.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3431 PF11913.8 KUM59796.1 - 3.8e-85 285.0 1.6 4.9e-85 284.7 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Sporozoite_P67 PF05642.11 KUM59797.1 - 0.00013 20.2 8.8 0.00017 19.8 8.8 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF4611 PF15387.6 KUM59797.1 - 0.1 12.8 2.5 0.24 11.7 2.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 KUM59797.1 - 0.15 12.5 8.2 0.29 11.5 8.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFIIF_alpha PF05793.12 KUM59797.1 - 0.49 8.9 10.8 0.61 8.6 10.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Herpes_capsid PF06112.11 KUM59797.1 - 0.71 9.9 15.8 1 9.4 15.8 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PI3K_1B_p101 PF10486.9 KUM59797.1 - 0.94 7.2 5.5 1.2 6.9 5.5 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Cwf_Cwc_15 PF04889.12 KUM59797.1 - 1.2 8.8 12.6 0.15 11.7 8.7 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Apt1 PF10351.9 KUM59797.1 - 1.5 7.6 6.1 1.8 7.3 6.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM176 PF14851.6 KUM59797.1 - 2.3 7.9 6.7 1.8 8.2 5.0 1.7 1 1 1 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 KUM59797.1 - 2.5 6.1 4.8 3.3 5.7 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Macoilin PF09726.9 KUM59797.1 - 2.9 6.3 6.1 3.3 6.2 6.1 1.0 1 0 0 1 1 1 0 Macoilin family CAF1-p150_C2 PF15539.6 KUM59797.1 - 5.3 6.4 11.7 2.1 7.7 9.5 1.6 1 1 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Histone PF00125.24 KUM59798.1 - 1.1e-16 61.4 0.0 1.4e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KUM59798.1 - 1e-11 44.3 0.0 2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KUM59798.1 - 3.5e-05 24.0 0.0 4.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.22 KUM59799.1 - 9.6e-11 41.5 0.1 1.7e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KUM59799.1 - 5.2e-06 26.2 0.1 9.7e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ-C PF12901.7 KUM59799.1 - 0.01 15.8 5.5 0.039 14.0 5.5 2.1 1 0 0 1 1 1 0 SUZ-C motif Bys1 PF04681.12 KUM59800.1 - 1.6e-14 54.2 1.2 1.8e-14 53.9 1.2 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Thermopsin PF05317.11 KUM59800.1 - 0.038 13.4 0.0 0.045 13.2 0.0 1.1 1 0 0 1 1 1 0 Thermopsin Pho88 PF10032.9 KUM59801.1 - 1.1e-79 266.0 0.0 1.2e-79 265.8 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) GAD-like PF08887.11 KUM59801.1 - 0.16 11.7 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 GAD-like domain GRIM-19 PF06212.12 KUM59802.1 - 0.17 11.8 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 GRIM-19 protein Gp_dh_C PF02800.20 KUM59803.1 - 6.8e-72 240.2 0.0 9.7e-72 239.7 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KUM59803.1 - 4.8e-39 132.8 0.2 1.6e-38 131.1 0.1 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KUM59803.1 - 0.0038 17.3 0.1 0.013 15.6 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Cellulase PF00150.18 KUM59804.1 - 7.9e-39 133.8 0.4 3.7e-38 131.6 0.2 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 KUM59804.1 - 1e-25 89.6 4.0 2.8e-22 78.6 1.0 3.5 2 1 0 2 2 2 2 Carbohydrate binding domain X2 MINDY_DUB PF04424.13 KUM59805.1 - 1.3e-20 73.6 0.0 2.3e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase RSN1_7TM PF02714.15 KUM59806.1 - 3e-84 282.6 21.2 3e-84 282.6 21.2 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KUM59806.1 - 1.7e-34 119.6 0.9 3.6e-34 118.5 0.9 1.6 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KUM59806.1 - 1.5e-29 102.0 1.5 4.4e-29 100.5 1.5 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RSN1_TM PF13967.6 KUM59806.1 - 1.1e-05 25.2 2.0 2.5e-05 24.1 0.1 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport kleA_kleC PF17383.2 KUM59806.1 - 0.0069 16.7 2.2 0.0095 16.2 0.2 2.2 3 0 0 3 3 3 1 Uncharacterized KorC regulated protein A RRM_1 PF00076.22 KUM59806.1 - 0.12 12.2 0.0 0.34 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gcd10p PF04189.13 KUM59807.1 - 6.9e-116 386.6 0.0 8.6e-116 386.2 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family AnmK PF03702.14 KUM59807.1 - 0.029 13.5 0.0 4 6.4 0.0 2.1 1 1 1 2 2 2 0 Anhydro-N-acetylmuramic acid kinase P21-Arc PF04062.14 KUM59808.1 - 9.3e-73 244.0 0.0 1e-72 243.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit IHO1 PF15771.5 KUM59808.1 - 0.099 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 Peptidase_M16_M PF16187.5 KUM59809.1 - 1.2e-97 326.6 1.1 2e-97 325.8 1.1 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KUM59809.1 - 4.3e-34 118.1 0.3 1.3e-21 77.4 0.0 4.7 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KUM59809.1 - 5e-32 110.9 6.2 6.9e-31 107.2 2.7 3.7 2 2 1 3 3 3 1 Insulinase (Peptidase family M16) Bac_thur_toxin PF01338.18 KUM59809.1 - 0.0046 16.5 0.2 0.88 9.0 0.0 3.2 3 0 0 3 3 3 1 Bacillus thuringiensis toxin Phage_int_SAM_1 PF02899.17 KUM59809.1 - 0.0072 16.6 1.4 0.98 9.8 0.2 3.7 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain DUF3208 PF11482.8 KUM59809.1 - 0.08 13.3 0.2 0.43 10.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3208) Arb2 PF09757.9 KUM59810.1 - 4.4e-97 324.2 0.3 5.9e-97 323.8 0.3 1.1 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 KUM59810.1 - 1.1e-83 281.3 0.0 2e-83 280.4 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain DUF3618 PF12277.8 KUM59811.1 - 0.13 12.5 0.0 0.4 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Mog1 PF04603.12 KUM59812.1 - 7.5e-28 97.6 0.0 2.2e-27 96.1 0.0 1.8 1 1 0 1 1 1 1 Ran-interacting Mog1 protein HSP9_HSP12 PF04119.12 KUM59813.1 - 1.2e-26 92.8 10.1 1.5e-26 92.5 9.4 1.5 2 0 0 2 2 2 1 Heat shock protein 9/12 YtxH PF12732.7 KUM59813.1 - 0.24 12.0 2.5 0.26 11.9 1.5 1.7 1 1 1 2 2 2 0 YtxH-like protein AAA_13 PF13166.6 KUM59814.1 - 0.13 10.9 4.8 0.15 10.7 4.8 1.2 1 0 0 1 1 1 0 AAA domain DUF2730 PF10805.8 KUM59814.1 - 0.13 12.4 5.2 7 6.8 0.2 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) GreA_GreB_N PF03449.15 KUM59814.1 - 0.15 12.2 4.5 13 6.0 0.2 3.5 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal Laminin_II PF06009.12 KUM59814.1 - 0.16 12.0 4.2 0.73 9.9 0.6 2.5 2 1 1 3 3 3 0 Laminin Domain II FapA PF03961.13 KUM59814.1 - 0.21 10.1 2.6 0.26 9.9 1.0 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A Spc7 PF08317.11 KUM59814.1 - 0.23 10.3 9.9 0.14 11.0 4.4 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 KUM59814.1 - 1.6 8.0 10.4 2.3 7.5 0.5 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 KUM59814.1 - 2.4 8.0 7.9 10 6.0 1.0 3.6 3 0 0 3 3 3 0 Septum formation initiator DUF4407 PF14362.6 KUM59814.1 - 5.1 6.4 12.3 0.15 11.3 2.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) IBR PF01485.21 KUM59815.1 - 2.6e-21 75.6 45.3 2.7e-12 46.7 5.7 4.4 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KUM59815.1 - 0.00011 22.5 3.8 0.00011 22.5 3.8 3.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KUM59815.1 - 0.00051 19.9 3.8 0.00051 19.9 3.8 4.4 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.8 KUM59815.1 - 0.011 16.3 0.0 0.021 15.3 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-C3HC4_2 PF13923.6 KUM59815.1 - 0.011 15.6 5.3 0.011 15.6 5.3 4.3 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KUM59815.1 - 0.014 15.4 4.1 0.014 15.4 4.1 3.8 3 1 0 3 3 3 0 RING-type zinc-finger Trp_syntA PF00290.20 KUM59815.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain NYN PF01936.18 KUM59816.1 - 0.00044 20.7 0.0 0.0024 18.4 0.0 2.1 1 1 0 1 1 1 1 NYN domain COG6 PF06419.11 KUM59817.1 - 8.7e-216 718.0 0.3 1e-215 717.8 0.3 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Transcrip_act PF04949.13 KUM59817.1 - 0.0022 17.9 0.8 0.0092 15.9 0.8 2.1 1 0 0 1 1 1 1 Transcriptional activator COG2 PF06148.11 KUM59817.1 - 0.031 14.4 2.9 0.061 13.4 1.2 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cep57_CLD PF14073.6 KUM59817.1 - 0.045 13.8 1.8 0.089 12.8 1.8 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 GARP PF16731.5 KUM59817.1 - 0.07 12.8 1.4 0.14 11.8 0.6 1.9 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Laminin_II PF06009.12 KUM59817.1 - 0.16 12.0 1.3 0.47 10.5 1.3 1.8 1 0 0 1 1 1 0 Laminin Domain II DUF948 PF06103.11 KUM59817.1 - 0.76 10.1 2.3 2.1 8.7 1.2 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA PF00004.29 KUM59818.1 - 6e-38 130.3 0.0 1.2e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KUM59818.1 - 1.3e-08 34.7 0.0 1.9e-07 31.0 0.0 2.9 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KUM59818.1 - 2.6e-07 30.3 0.0 5.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KUM59818.1 - 3.8e-05 24.0 2.7 0.00025 21.3 0.2 3.3 3 1 0 3 3 3 1 AAA domain AAA_2 PF07724.14 KUM59818.1 - 7.7e-05 22.9 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KUM59818.1 - 0.00011 22.0 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KUM59818.1 - 0.00048 20.6 1.1 0.0022 18.4 0.2 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KUM59818.1 - 0.00082 19.4 0.1 0.0039 17.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KUM59818.1 - 0.00093 18.5 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KUM59818.1 - 0.0043 16.4 0.4 0.0098 15.3 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KUM59818.1 - 0.0067 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KUM59818.1 - 0.021 15.0 0.0 0.06 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KUM59818.1 - 0.024 13.8 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 KUM59818.1 - 0.035 14.1 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KUM59818.1 - 0.057 13.0 0.0 0.24 10.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KUM59818.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KUM59818.1 - 0.091 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KUM59818.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 KUM59818.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 KUM59818.1 - 0.15 12.6 0.0 0.37 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.27 KUM59819.1 - 5.3e-51 170.5 5.6 1.2e-19 70.0 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein W2 PF02020.18 KUM59820.1 - 4.5e-19 68.4 7.0 4.5e-19 68.4 7.0 2.5 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KUM59820.1 - 2.6e-11 42.8 16.6 2.5e-06 27.0 1.5 4.3 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KUM59820.1 - 5.9e-07 29.3 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 KUM59820.1 - 1.4e-05 24.7 13.2 0.022 14.5 0.8 4.2 1 1 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 KUM59820.1 - 0.0002 21.7 0.0 0.00041 20.8 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KUM59820.1 - 0.027 12.6 1.0 0.057 11.6 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) adh_short PF00106.25 KUM59822.1 - 2.6e-37 128.2 0.0 3.4e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM59822.1 - 1.2e-20 74.1 0.0 1.4e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM59822.1 - 2.9e-07 30.6 0.0 5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KUM59822.1 - 4.3e-05 23.8 0.2 8.1e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KUM59822.1 - 0.0064 17.1 0.1 0.014 16.0 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KUM59822.1 - 0.0087 16.1 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KUM59822.1 - 0.025 14.5 0.1 0.052 13.4 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 KUM59822.1 - 0.046 13.2 0.2 0.26 10.7 0.2 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KUM59822.1 - 0.11 11.6 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SprT-like PF10263.9 KUM59823.1 - 5.1e-27 94.0 0.3 1.1e-26 93.0 0.3 1.5 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KUM59823.1 - 0.039 13.9 2.6 0.091 12.7 2.6 1.7 1 0 0 1 1 1 0 SprT-like zinc ribbon domain SPT6_acidic PF14632.6 KUM59823.1 - 3.5 8.3 10.4 2.6 8.7 6.8 2.7 2 0 0 2 2 2 0 Acidic N-terminal SPT6 SET PF00856.28 KUM59824.1 - 2.3e-08 34.6 0.1 2.8e-08 34.3 0.1 1.5 1 1 0 1 1 1 1 SET domain GMC_oxred_C PF05199.13 KUM59825.1 - 4.2e-09 37.1 0.0 9e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase HMA PF00403.26 KUM59827.1 - 2e-51 172.3 0.1 3.1e-12 46.8 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 KUM59827.1 - 1.6e-46 158.1 0.6 6.4e-46 156.1 0.6 2.1 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KUM59827.1 - 6.1e-36 124.7 0.2 1.6e-35 123.3 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KUM59827.1 - 3e-05 23.9 0.8 0.00017 21.5 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase EccE PF11203.8 KUM59827.1 - 0.035 14.4 0.6 6.8 7.1 0.4 3.9 4 0 0 4 4 4 0 Putative type VII ESX secretion system translocon, EccE Ank_4 PF13637.6 KUM59828.1 - 1e-14 54.7 0.2 5.7 7.6 0.0 8.7 9 0 0 9 9 9 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM59828.1 - 3.7e-13 49.4 1.3 0.33 11.3 0.0 7.7 10 0 0 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM59828.1 - 2.4e-06 27.4 0.0 55 4.8 0.0 7.3 8 0 0 8 8 8 0 Ankyrin repeat Ank PF00023.30 KUM59828.1 - 3e-06 27.4 1.5 16 6.2 0.0 7.0 8 0 0 8 8 8 2 Ankyrin repeat Ank_2 PF12796.7 KUM59828.1 - 2.6e-05 24.7 0.0 24 5.6 0.0 6.0 5 2 1 6 6 6 1 Ankyrin repeats (3 copies) Fungal_trans_2 PF11951.8 KUM59831.1 - 7.1e-06 25.1 0.6 1.1e-05 24.5 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TUG-UBL1 PF11470.8 KUM59831.1 - 0.06 13.6 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 TUG ubiquitin-like domain Peroxidase_2 PF01328.17 KUM59832.1 - 5e-43 147.8 0.0 6.5e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 GMC_oxred_N PF00732.19 KUM59833.1 - 2.1e-76 257.1 0.0 2.9e-76 256.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM59833.1 - 7.3e-35 120.6 0.2 8.9e-34 117.1 0.2 2.2 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KUM59833.1 - 2.9e-06 26.6 0.0 0.0016 17.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KUM59833.1 - 0.00024 20.3 0.1 0.00041 19.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KUM59833.1 - 0.0016 17.8 0.1 0.013 14.7 0.1 2.0 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KUM59833.1 - 0.0034 17.0 0.9 0.023 14.3 0.6 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM59833.1 - 0.14 11.4 0.0 0.42 9.8 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2OG-FeII_Oxy_2 PF13532.6 KUM59834.1 - 2.2e-27 96.5 0.0 4.5e-27 95.5 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 KUM59835.1 - 2.1e-69 233.9 0.0 2.7e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM59835.1 - 2e-30 105.9 0.0 2.6e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KUM59835.1 - 0.0002 20.5 0.0 0.012 14.6 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 KUM59835.1 - 0.00029 20.2 0.0 0.00056 19.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KUM59835.1 - 0.0034 17.3 0.0 0.0077 16.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KUM59835.1 - 0.0089 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 KUM59835.1 - 0.14 11.4 0.0 0.32 10.3 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C2 PF00648.21 KUM59836.1 - 1.2e-63 214.9 0.7 9.8e-42 143.0 0.1 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease Fungal_trans PF04082.18 KUM59837.1 - 2.5e-19 69.3 0.0 4.2e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase PF00903.25 KUM59838.1 - 8e-43 145.7 0.0 6.3e-21 74.9 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KUM59838.1 - 5.6e-16 58.8 0.0 1.4e-05 25.3 0.0 3.9 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KUM59838.1 - 3.9e-07 30.3 0.0 0.005 17.0 0.0 3.6 2 1 1 3 3 3 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KUM59838.1 - 6.5e-06 26.9 0.0 0.14 13.0 0.0 2.9 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KUM59838.1 - 0.0027 17.6 0.2 5.5 6.9 0.0 3.9 4 0 0 4 4 4 1 Glyoxalase-like domain CppA_N PF14506.6 KUM59838.1 - 0.042 13.9 0.1 0.43 10.7 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal DUF1338 PF07063.13 KUM59838.1 - 0.093 11.9 0.0 11 5.1 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1338) PRT_C PF08372.10 KUM59838.1 - 0.21 11.3 0.0 3.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Abhydrolase_3 PF07859.13 KUM59839.1 - 4e-07 30.1 0.0 2.7e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KUM59839.1 - 0.00042 20.3 0.0 0.00094 19.2 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 KUM59839.1 - 0.0039 16.9 0.0 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KUM59839.1 - 0.0048 16.4 0.0 0.0085 15.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KUM59839.1 - 0.037 13.7 0.0 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Putative esterase COesterase PF00135.28 KUM59839.1 - 0.053 12.4 0.2 0.56 9.0 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family MFS_1 PF07690.16 KUM59841.1 - 1.1e-36 126.5 25.1 1.1e-36 126.5 25.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KUM59841.1 - 4.8e-07 29.4 0.1 4.8e-07 29.4 0.1 1.9 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Phage_holin_5_2 PF16079.5 KUM59841.1 - 0.18 12.2 4.7 1.1 9.6 0.2 3.6 3 1 1 4 4 4 0 Phage holin family Hol44, in holin superfamily V DUF4185 PF13810.6 KUM59842.1 - 0.072 12.3 0.0 0.08 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) ThiJ_like PF17124.5 KUM59843.1 - 2.1e-10 40.7 0.0 2.8e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 KUM59843.1 - 7.9e-10 38.8 0.0 3.9e-09 36.5 0.0 2.2 1 1 0 1 1 1 1 DJ-1/PfpI family Glyco_transf_4 PF13439.6 KUM59843.1 - 0.051 13.6 0.0 0.21 11.6 0.0 1.8 1 1 0 1 1 1 0 Glycosyltransferase Family 4 IstB_IS21 PF01695.17 KUM59844.1 - 3e-05 23.8 0.0 7.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 KUM59844.1 - 8.1e-05 23.1 0.7 0.0089 16.4 0.0 2.9 3 1 1 4 4 4 1 AAA ATPase domain AAA_13 PF13166.6 KUM59844.1 - 8.7e-05 21.4 0.1 0.22 10.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KUM59844.1 - 0.00019 21.4 0.0 0.001 19.1 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KUM59844.1 - 0.00042 20.6 0.1 0.021 15.1 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 KUM59844.1 - 0.0045 16.7 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KUM59844.1 - 0.016 15.6 0.0 0.045 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KUM59844.1 - 0.047 14.1 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Allexi_40kDa PF05549.11 KUM59844.1 - 0.052 13.1 0.2 0.052 13.1 0.2 2.8 3 1 1 4 4 4 0 Allexivirus 40kDa protein NACHT PF05729.12 KUM59844.1 - 0.061 13.2 1.9 0.13 12.2 0.1 2.6 3 1 0 3 3 3 0 NACHT domain TniB PF05621.11 KUM59844.1 - 0.067 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Zeta_toxin PF06414.12 KUM59844.1 - 0.067 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 KUM59844.1 - 0.13 11.6 0.0 0.34 10.2 0.0 1.7 1 0 0 1 1 1 0 KaiC zf-C2H2_4 PF13894.6 KUM59845.1 - 0.17 12.8 0.4 0.47 11.4 0.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Amidase PF01425.21 KUM59846.1 - 6.5e-79 266.0 0.0 9.2e-79 265.5 0.0 1.2 1 0 0 1 1 1 1 Amidase Transcrip_act PF04949.13 KUM59847.1 - 0.043 13.7 0.1 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Transcriptional activator ABC2_membrane PF01061.24 KUM59848.1 - 1.3e-74 250.2 66.5 2.7e-38 131.5 22.7 4.0 3 1 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KUM59848.1 - 4.6e-37 127.6 0.0 1.1e-17 64.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KUM59848.1 - 1.2e-33 114.8 2.2 7.1e-27 93.2 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KUM59848.1 - 3.5e-10 40.3 0.0 2e-09 37.9 0.1 2.3 2 0 0 2 2 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KUM59848.1 - 7.6e-09 35.1 27.3 0.00034 19.8 9.1 3.1 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KUM59848.1 - 1.5e-07 32.0 0.1 1.3e-05 25.7 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KUM59848.1 - 8.4e-07 29.0 0.2 3.9e-06 26.9 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KUM59848.1 - 4e-06 27.4 0.0 0.0058 17.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KUM59848.1 - 7.3e-06 26.0 2.0 0.074 12.8 0.3 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KUM59848.1 - 1.8e-05 24.3 0.1 0.0058 16.4 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KUM59848.1 - 9.3e-05 22.7 0.3 0.071 13.4 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KUM59848.1 - 0.00017 21.3 0.0 0.0031 17.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KUM59848.1 - 0.001 18.8 0.1 0.044 13.5 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KUM59848.1 - 0.0012 19.1 0.4 0.0042 17.3 0.1 2.1 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KUM59848.1 - 0.0012 19.0 0.0 0.12 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KUM59848.1 - 0.0025 18.3 0.3 0.16 12.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KUM59848.1 - 0.003 17.5 0.1 0.037 14.0 0.0 2.3 2 0 0 2 2 2 1 NACHT domain ABC_ATPase PF09818.9 KUM59848.1 - 0.0031 16.4 0.1 1.3 7.8 0.1 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class cobW PF02492.19 KUM59848.1 - 0.009 15.6 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KUM59848.1 - 0.0091 16.1 0.4 0.53 10.4 0.3 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KUM59848.1 - 0.0093 15.3 0.6 1.7 7.9 0.1 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.6 KUM59848.1 - 0.015 15.8 0.2 0.045 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KUM59848.1 - 0.035 13.6 0.3 5.9 6.3 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain dNK PF01712.19 KUM59848.1 - 0.059 13.2 0.0 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase T2SSE PF00437.20 KUM59848.1 - 0.065 12.3 0.1 0.22 10.5 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 KUM59848.1 - 0.071 13.5 0.1 3.5 8.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 KUM59848.1 - 0.089 13.2 0.0 1.1 9.7 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KUM59848.1 - 0.15 11.4 0.0 4.3 6.6 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain adh_short PF00106.25 KUM59850.1 - 4.7e-17 62.1 0.0 6.9e-14 51.7 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KUM59850.1 - 5.3e-08 33.0 0.0 1.4e-07 31.6 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 KUM59850.1 - 3e-06 27.0 0.0 1.2e-05 24.9 0.0 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KUM59850.1 - 3.4e-06 26.7 0.0 6.4e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KUM59850.1 - 0.027 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family E1-N PF14463.6 KUM59850.1 - 0.055 13.3 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 E1 N-terminal domain RmlD_sub_bind PF04321.17 KUM59850.1 - 0.058 12.5 0.1 0.17 11.0 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 KUM59850.1 - 0.071 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H-binding G-patch PF01585.23 KUM59851.1 - 0.0018 18.2 0.1 0.004 17.0 0.1 1.5 1 0 0 1 1 1 1 G-patch domain PAT1 PF09770.9 KUM59852.1 - 0 1176.6 0.1 0 1175.7 0.1 1.4 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Epimerase PF01370.21 KUM59853.1 - 4.3e-47 160.6 0.0 6.9e-47 159.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM59853.1 - 1.3e-46 159.6 0.0 4.3e-46 157.9 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KUM59853.1 - 9.4e-15 54.3 0.0 1.5e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KUM59853.1 - 7.9e-12 44.9 0.0 6.1e-10 38.7 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KUM59853.1 - 1.4e-10 40.8 0.0 2.3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KUM59853.1 - 2.3e-08 33.7 0.0 6e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KUM59853.1 - 1.4e-05 25.1 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KUM59853.1 - 0.0001 22.0 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KUM59853.1 - 0.00011 22.1 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KUM59853.1 - 0.00095 18.4 0.0 0.0095 15.1 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KUM59853.1 - 0.084 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Cys_Met_Meta_PP PF01053.20 KUM59853.1 - 0.14 10.7 0.0 0.7 8.4 0.0 1.9 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme UDPG_MGDP_dh_N PF03721.14 KUM59853.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_31 PF13847.6 KUM59854.1 - 7e-07 29.2 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM59854.1 - 2.3e-06 28.2 0.0 5.4e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM59854.1 - 7.7e-05 22.6 0.0 0.00011 22.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KUM59854.1 - 0.0009 20.2 0.0 0.0023 18.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM59854.1 - 0.0013 19.3 0.0 0.003 18.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KUM59854.1 - 0.002 17.9 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 KUM59854.1 - 0.0032 16.7 0.0 0.005 16.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_32 PF13679.6 KUM59854.1 - 0.037 14.0 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KUM59854.1 - 0.043 13.2 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KUM59854.1 - 0.2 12.4 0.1 0.58 10.9 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain IceA2 PF05862.11 KUM59855.1 - 0.0045 16.9 2.6 2.9 7.9 0.2 3.7 1 1 2 3 3 3 3 Helicobacter pylori IceA2 protein SinI PF08671.10 KUM59855.1 - 0.038 13.8 0.2 2e+02 1.8 0.0 4.0 4 0 0 4 4 4 0 Anti-repressor SinI GRASP55_65 PF04495.14 KUM59855.1 - 0.27 11.5 11.0 2.4e+02 2.0 0.0 5.4 1 1 1 2 2 2 0 GRASP55/65 PDZ-like domain FAM199X PF15814.5 KUM59856.1 - 0.023 13.7 1.3 0.031 13.3 1.3 1.1 1 0 0 1 1 1 0 Protein family FAM199X Npa1 PF11707.8 KUM59857.1 - 3.1e-98 329.3 0.0 9.7e-98 327.6 0.0 1.9 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KUM59857.1 - 1.1e-56 191.6 0.1 5.2e-56 189.4 0.0 2.3 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Acetyltransf_1 PF00583.25 KUM59858.1 - 2.2e-07 31.1 0.0 3.5e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KUM59858.1 - 5.7e-07 29.5 0.0 9.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KUM59858.1 - 1.1e-06 28.9 0.0 1.9e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KUM59858.1 - 0.00031 20.7 0.0 0.00049 20.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KUM59858.1 - 0.058 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ABC_tran_CTD PF16326.5 KUM59859.1 - 0.087 13.1 2.3 0.098 12.9 1.1 1.7 1 1 1 2 2 2 0 ABC transporter C-terminal domain HA2 PF04408.23 KUM59860.1 - 7.4e-24 84.1 0.1 7.4e-24 84.1 0.1 2.5 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KUM59860.1 - 1.3e-20 73.5 0.0 2.8e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KUM59860.1 - 5.2e-14 52.5 0.0 1.2e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KUM59860.1 - 1.1e-10 41.7 0.8 2.3e-10 40.7 0.8 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 KUM59860.1 - 0.0001 22.1 0.0 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KUM59860.1 - 0.00064 18.9 0.0 0.0014 17.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KUM59860.1 - 0.0017 18.6 0.0 0.0045 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KUM59860.1 - 0.003 17.3 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KUM59860.1 - 0.021 15.2 0.1 0.043 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KUM59860.1 - 0.082 12.2 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 KUM59860.1 - 0.19 11.5 0.0 0.56 10.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain G_glu_transpept PF01019.21 KUM59861.1 - 1.7e-141 472.5 0.0 1.9e-141 472.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MFS_1 PF07690.16 KUM59862.1 - 2.1e-18 66.4 45.6 1.5e-16 60.3 12.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.27 KUM59863.1 - 9.9e-46 155.7 0.0 9.1e-29 100.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KUM59863.1 - 1.9e-39 136.0 27.2 3.4e-26 92.5 9.9 3.6 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 KUM59863.1 - 8.9e-14 51.4 0.0 4.5e-06 26.3 0.0 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KUM59863.1 - 0.00016 22.2 0.1 0.37 11.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KUM59863.1 - 0.00017 21.7 0.2 0.04 14.0 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase DUF87 PF01935.17 KUM59863.1 - 0.00029 21.0 1.3 0.063 13.4 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 KUM59863.1 - 0.00031 21.0 0.0 1.8 8.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 KUM59863.1 - 0.00063 19.6 0.1 1.5 8.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KUM59863.1 - 0.00093 18.9 0.7 1.3 8.9 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF2075 PF09848.9 KUM59863.1 - 0.0039 16.5 0.1 0.75 9.0 0.0 3.0 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KUM59863.1 - 0.0041 17.5 0.0 0.78 10.2 0.0 3.4 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KUM59863.1 - 0.0064 16.4 0.1 2.4 8.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KUM59863.1 - 0.0092 16.4 1.0 2.8 8.3 0.0 3.0 3 0 0 3 3 2 1 AAA ATPase domain AAA_10 PF12846.7 KUM59863.1 - 0.013 14.4 0.1 1.2 8.0 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain NB-ARC PF00931.22 KUM59863.1 - 0.014 14.6 0.2 16 4.6 0.1 3.3 3 0 0 3 3 3 0 NB-ARC domain PIEZO PF15917.5 KUM59863.1 - 0.014 14.9 0.3 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Piezo IstB_IS21 PF01695.17 KUM59863.1 - 0.017 14.9 0.5 0.56 9.9 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_30 PF13604.6 KUM59863.1 - 0.067 12.9 0.0 5.1 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KUM59863.1 - 0.074 13.5 0.1 23 5.4 0.0 2.9 3 0 0 3 3 2 0 RNA helicase T2SSE PF00437.20 KUM59863.1 - 0.087 11.9 0.0 2.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.6 KUM59863.1 - 0.18 11.4 0.1 6.2 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KUM59863.1 - 0.68 9.8 4.0 6.2 6.7 0.1 3.5 3 0 0 3 3 3 0 NACHT domain adh_short_C2 PF13561.6 KUM59864.1 - 3.5e-56 190.4 0.0 4.2e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM59864.1 - 2.3e-46 157.7 0.0 2.9e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM59864.1 - 1.8e-14 54.0 0.0 2.5e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KUM59864.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) SUV3_C PF12513.8 KUM59865.1 - 1.5e-17 63.2 0.7 3.5e-17 62.1 0.2 1.9 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KUM59865.1 - 8.1e-11 42.2 0.0 1.6e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 KUM59865.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 Sec1 PF00995.23 KUM59866.1 - 2.5e-114 383.6 0.0 3.7e-114 383.1 0.0 1.2 1 0 0 1 1 1 1 Sec1 family SR-25 PF10500.9 KUM59866.1 - 0.095 12.3 9.0 0.17 11.5 9.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dus PF01207.17 KUM59867.1 - 1.2e-59 201.9 0.0 1.7e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KUM59867.1 - 0.00097 18.4 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase WD40 PF00400.32 KUM59868.1 - 0.00059 20.6 2.3 12 7.0 0.5 5.0 4 1 1 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.12 KUM59868.1 - 0.0054 16.6 0.4 0.55 10.3 0.2 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KUM59868.1 - 0.02 14.6 0.4 1.5 8.6 0.0 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature NOG1_N PF17835.1 KUM59869.1 - 1.1e-48 165.2 1.0 2e-48 164.4 0.1 1.9 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KUM59869.1 - 1.5e-27 95.3 4.1 3.7e-27 94.1 4.1 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KUM59869.1 - 1e-25 89.3 0.2 2.1e-25 88.3 0.2 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KUM59869.1 - 9.4e-16 57.9 0.0 2.1e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KUM59869.1 - 2.8e-07 30.2 0.0 8.7e-07 28.6 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KUM59869.1 - 0.0061 16.5 0.0 1.5 8.7 0.1 2.7 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KUM59869.1 - 0.0074 16.4 0.0 4.5 7.3 0.0 2.6 1 1 0 2 2 2 2 Dynamin family AAA_16 PF13191.6 KUM59869.1 - 0.042 14.2 0.1 0.36 11.2 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain Sugar_tr PF00083.24 KUM59870.1 - 5.2e-132 440.9 30.4 1.5e-131 439.4 30.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM59870.1 - 3.9e-25 88.5 48.0 1.1e-20 73.9 28.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KUM59870.1 - 0.024 14.9 1.8 0.024 14.9 1.8 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) DUF4293 PF14126.6 KUM59870.1 - 0.027 14.7 0.7 0.027 14.7 0.7 3.1 2 1 3 5 5 5 0 Domain of unknown function (DUF4293) NAD_binding_2 PF03446.15 KUM59871.1 - 2.8e-22 79.6 0.0 4.3e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KUM59871.1 - 2.1e-08 34.4 0.3 6.3e-08 32.9 0.3 1.8 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 KUM59871.1 - 0.0041 17.2 0.0 0.008 16.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DSBA PF01323.20 KUM59872.1 - 2.5e-11 43.7 0.0 2.8e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Sugar_tr PF00083.24 KUM59873.1 - 4.5e-84 282.9 27.6 5.1e-84 282.7 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM59873.1 - 4.5e-19 68.6 21.8 1.2e-18 67.2 12.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DPM3 PF08285.11 KUM59874.1 - 0.0016 18.6 1.9 0.021 15.0 0.0 2.4 1 1 1 2 2 2 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DctQ PF04290.12 KUM59874.1 - 0.031 14.2 9.6 0.066 13.1 4.1 2.8 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component TatC PF00902.18 KUM59874.1 - 0.087 12.6 4.4 0.17 11.7 4.4 1.5 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) NAT PF04768.13 KUM59875.1 - 2e-52 177.3 0.0 3.9e-51 173.1 0.0 2.3 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Acetyltransf_1 PF00583.25 KUM59876.1 - 1.5e-14 54.2 0.0 2.9e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KUM59876.1 - 3.2e-13 49.7 0.0 4.6e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KUM59876.1 - 1.3e-10 41.5 0.0 2.2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KUM59876.1 - 0.003 17.6 0.0 0.007 16.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KUM59876.1 - 0.0038 17.3 0.0 0.0068 16.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KUM59876.1 - 0.021 14.8 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein PYST-C1 PF09690.10 KUM59876.1 - 0.19 11.5 1.9 0.42 10.4 1.9 1.6 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) MFS_1 PF07690.16 KUM59878.1 - 2.3e-42 145.2 52.4 5.3e-42 144.0 47.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM59878.1 - 0.00012 21.1 29.4 0.0013 17.6 29.4 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter Erg28 PF03694.13 KUM59879.1 - 2.5e-37 127.6 0.7 2.9e-37 127.4 0.7 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.22 KUM59880.1 - 2.2e-70 236.8 0.3 1.1e-68 231.3 0.1 2.3 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KUM59880.1 - 1.4e-58 197.3 0.3 3.4e-58 196.1 0.1 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 KUM59880.1 - 0.0039 16.1 0.1 0.23 10.2 0.0 2.5 2 1 1 3 3 3 2 Domain of unknown function (DUF4921) HIT PF01230.23 KUM59880.1 - 0.023 15.4 0.0 0.091 13.5 0.0 2.0 2 1 0 2 2 2 0 HIT domain TRAP-gamma PF07074.12 KUM59880.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Flavoprotein PF02441.19 KUM59881.1 - 4.7e-47 159.7 0.1 1.1e-46 158.4 0.1 1.6 1 1 0 1 1 1 1 Flavoprotein Ribosomal_L12_N PF16320.5 KUM59881.1 - 0.028 14.1 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain adh_short PF00106.25 KUM59882.1 - 3.1e-36 124.7 0.0 5.1e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM59882.1 - 4.2e-22 78.9 0.0 5.6e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM59882.1 - 0.00042 20.3 0.0 0.00078 19.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KUM59882.1 - 0.094 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HSP70 PF00012.20 KUM59884.1 - 1.6e-08 33.2 0.0 2e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KUM59884.1 - 8.7e-06 24.8 0.2 8.3e-05 21.5 0.2 2.0 1 1 0 1 1 1 1 MreB/Mbl protein Actin PF00022.19 KUM59884.1 - 0.025 13.2 0.0 0.052 12.2 0.0 1.4 1 0 0 1 1 1 0 Actin Ribosomal_L7Ae PF01248.26 KUM59885.1 - 1.9e-24 85.2 0.0 2.3e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KUM59885.1 - 3.6e-05 23.9 0.0 3.6e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KUM59885.1 - 0.025 14.4 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain DUF3533 PF12051.8 KUM59887.1 - 2.8e-96 322.7 14.2 3.2e-96 322.5 14.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Trp_halogenase PF04820.14 KUM59888.1 - 5.6e-07 28.8 0.1 0.0011 17.9 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 KUM59888.1 - 5.5e-06 26.2 0.7 4.4e-05 23.2 0.4 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM59888.1 - 3.2e-05 23.3 0.7 0.00015 21.2 0.7 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM59888.1 - 5.2e-05 23.4 0.1 0.00017 21.8 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KUM59888.1 - 9.6e-05 21.8 0.1 0.024 13.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 KUM59888.1 - 0.00016 20.9 0.0 0.00064 18.9 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KUM59888.1 - 0.0036 16.1 0.1 0.0055 15.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KUM59888.1 - 0.018 14.3 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KUM59888.1 - 0.031 14.8 0.2 0.065 13.8 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KUM59888.1 - 0.035 13.2 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KUM59888.1 - 0.037 13.4 0.2 0.06 12.7 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KUM59888.1 - 0.048 12.9 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KUM59888.1 - 0.099 11.9 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family PhyH PF05721.13 KUM59889.1 - 2e-08 34.7 0.3 5.1e-08 33.4 0.3 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KUM59889.1 - 4.8e-07 28.9 0.0 0.16 10.7 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.6 KUM59889.1 - 0.036 14.9 0.0 0.077 13.9 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PTR2 PF00854.21 KUM59890.1 - 2.5e-25 89.2 0.0 3.8e-25 88.6 0.0 1.3 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 KUM59890.1 - 0.0016 17.5 0.8 0.0023 16.9 0.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KUM59890.1 - 0.024 13.5 0.3 0.051 12.4 0.0 1.6 2 0 0 2 2 2 0 MFS_1 like family Fungal_trans PF04082.18 KUM59891.1 - 1.2e-07 31.0 0.4 1.8e-07 30.5 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhyH PF05721.13 KUM59892.1 - 1.3e-06 28.9 0.0 4.1e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KUM59892.1 - 3.6e-05 22.7 0.2 0.15 10.8 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) Fungal_trans PF04082.18 KUM59893.1 - 1.5e-14 53.7 0.4 4e-14 52.3 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM59893.1 - 6.1e-09 35.9 14.0 1e-08 35.1 14.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S15 PF02129.18 KUM59894.1 - 3e-42 145.1 0.7 6.1e-40 137.5 0.1 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KUM59894.1 - 3.8e-32 112.0 0.0 5.8e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 KUM59894.1 - 0.01 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KUM59894.1 - 0.11 11.9 0.3 0.38 10.2 0.2 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family AXE1 PF05448.12 KUM59894.1 - 0.12 11.0 0.2 8.2 5.0 0.1 2.2 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Zn_clus PF00172.18 KUM59895.1 - 1.2e-05 25.3 11.2 2e-05 24.6 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM59895.1 - 5.3e-05 22.4 0.1 0.00012 21.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Prefoldin PF02996.17 KUM59896.1 - 3.7e-20 72.0 0.5 2.2e-19 69.5 0.5 1.9 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KUM59896.1 - 0.0052 16.7 0.3 0.26 11.3 0.1 2.1 2 0 0 2 2 2 1 Prefoldin subunit Sec2p PF06428.11 KUM59896.1 - 0.06 13.3 1.3 0.85 9.6 0.2 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF1192 PF06698.11 KUM59896.1 - 0.073 13.1 0.8 0.15 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) CLZ PF16526.5 KUM59896.1 - 0.59 10.5 4.2 3.4 8.1 0.3 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DASH_Hsk3 PF08227.11 KUM59896.1 - 0.7 10.3 4.5 0.88 10.0 0.0 2.4 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like KH_1 PF00013.29 KUM59897.1 - 0.0019 18.0 0.0 0.0073 16.1 0.0 2.0 2 0 0 2 2 2 1 KH domain AAA PF00004.29 KUM59898.1 - 4.4e-15 56.3 0.0 8.4e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KUM59898.1 - 6.1e-12 45.5 0.8 3.4e-11 43.1 0.5 2.2 1 1 1 2 2 2 1 AAA lid domain AAA_16 PF13191.6 KUM59898.1 - 5.2e-09 36.7 0.5 2.9e-08 34.3 0.0 2.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KUM59898.1 - 7.3e-09 36.0 0.0 2.3e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 KUM59898.1 - 3.3e-06 27.0 0.1 8.1e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 BAH domain AAA_28 PF13521.6 KUM59898.1 - 0.0037 17.5 0.0 0.013 15.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KUM59898.1 - 0.0048 17.2 0.1 0.012 15.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KUM59898.1 - 0.01 16.0 0.0 0.16 12.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain ssDBP PF17878.1 KUM59898.1 - 0.027 14.7 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 Single-stranded DNA-binding protein NACHT PF05729.12 KUM59898.1 - 0.027 14.4 0.0 0.063 13.2 0.0 1.6 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KUM59898.1 - 0.028 14.9 0.1 0.093 13.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 KUM59898.1 - 0.032 14.0 0.0 0.032 14.0 0.0 1.9 3 0 0 3 3 2 0 AAA domain DUF2075 PF09848.9 KUM59898.1 - 0.043 13.1 0.0 0.099 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Kinesin PF00225.23 KUM59898.1 - 0.044 12.7 0.0 0.077 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain PIF1 PF05970.14 KUM59898.1 - 0.045 12.9 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_32 PF13654.6 KUM59898.1 - 0.086 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KUM59898.1 - 0.1 12.5 0.0 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KUM59898.1 - 0.13 11.4 0.1 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 KUM59898.1 - 0.15 12.4 0.1 0.51 10.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase WD40 PF00400.32 KUM59899.1 - 4.5e-46 153.9 15.9 2.8e-09 37.4 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM59899.1 - 6.4e-07 29.6 0.4 3.6 8.0 0.1 5.2 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KUM59899.1 - 0.016 14.5 0.0 0.038 13.3 0.0 1.6 2 0 0 2 2 2 0 WD40-like domain DUF5018 PF16410.5 KUM59899.1 - 0.024 13.4 0.0 0.041 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) Nup160 PF11715.8 KUM59899.1 - 0.041 12.5 2.7 11 4.5 0.0 4.3 2 2 2 5 5 5 0 Nucleoporin Nup120/160 Ank_2 PF12796.7 KUM59900.1 - 1.2e-40 137.9 0.3 3.2e-11 43.7 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KUM59900.1 - 2.6e-34 116.8 0.1 3.5e-08 33.6 0.0 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KUM59900.1 - 2.6e-31 107.6 0.4 4.3e-10 39.9 0.0 5.0 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM59900.1 - 4.9e-28 94.1 0.0 0.002 18.5 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KUM59900.1 - 3.8e-23 80.9 0.2 0.00081 19.7 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat LHH PF14411.6 KUM59900.1 - 0.15 12.3 0.0 1 9.6 0.0 2.3 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH FMO-like PF00743.19 KUM59901.1 - 5.9e-21 74.5 0.3 2.3e-19 69.2 0.0 2.8 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KUM59901.1 - 2.3e-12 46.7 0.0 2e-10 40.4 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM59901.1 - 8.6e-12 44.9 0.0 1.8e-10 40.6 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM59901.1 - 8.2e-11 41.6 0.1 1.7e-06 27.4 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KUM59901.1 - 7.4e-08 32.5 0.0 1.9e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM59901.1 - 2.9e-07 30.4 0.0 2e-05 24.4 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KUM59901.1 - 9.4e-05 22.9 0.0 0.83 10.3 0.0 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KUM59901.1 - 0.00011 22.2 0.0 0.62 10.1 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KUM59901.1 - 0.00013 22.0 0.0 0.0028 17.7 0.0 2.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 KUM59901.1 - 0.00031 20.0 0.0 0.00075 18.8 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KUM59901.1 - 0.012 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 KUM59901.1 - 0.028 13.8 0.0 0.21 10.9 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KUM59901.1 - 0.049 12.7 0.0 0.19 10.8 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 KUM59901.1 - 0.13 11.0 0.2 0.23 10.1 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_7 PF13241.6 KUM59901.1 - 0.19 12.2 0.0 5.1 7.6 0.0 2.5 3 0 0 3 3 2 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KUM59901.1 - 0.2 11.9 0.5 14 5.9 0.1 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain MFS_1 PF07690.16 KUM59902.1 - 1.1e-24 87.1 36.9 1.1e-24 87.1 36.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MMPL PF03176.15 KUM59902.1 - 0.074 12.0 1.0 0.88 8.4 0.2 2.4 2 0 0 2 2 2 0 MMPL family LEF-9 PF05094.12 KUM59903.1 - 0.054 12.0 0.0 0.068 11.7 0.0 1.1 1 0 0 1 1 1 0 Late expression factor 9 (LEF-9) MFS_1 PF07690.16 KUM59905.1 - 5.9e-10 38.6 47.2 1.2e-06 27.7 19.1 3.5 2 2 2 4 4 4 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM59905.1 - 6.3e-10 38.5 9.6 6.3e-10 38.5 9.6 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Tom5 PF10642.9 KUM59905.1 - 0.14 12.2 0.6 0.37 10.9 0.6 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Fungal_trans PF04082.18 KUM59906.1 - 1.6e-05 24.0 0.6 2.5e-05 23.4 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2877 PF11392.8 KUM59906.1 - 0.0089 16.7 0.2 0.18 12.5 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2877) MFS_1 PF07690.16 KUM59907.1 - 3.9e-42 144.4 45.5 3.9e-42 144.4 45.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM59907.1 - 8.1e-18 64.2 15.2 8.1e-18 64.2 15.2 2.6 1 1 2 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM59907.1 - 6.2e-11 41.8 14.4 6.2e-11 41.8 14.4 3.5 3 1 1 4 4 4 1 Sugar (and other) transporter CbtB PF09489.10 KUM59907.1 - 0.039 14.1 0.5 3.6 7.8 0.2 3.4 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) CENP-F_leu_zip PF10473.9 KUM59908.1 - 0.077 13.0 20.5 0.029 14.4 16.4 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KUM59908.1 - 0.092 13.0 11.2 0.38 10.9 11.5 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 KUM59908.1 - 0.17 12.0 14.0 0.75 9.9 14.0 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Mannitol_dh PF01232.23 KUM59908.1 - 0.48 10.6 4.7 3 8.0 0.2 2.5 1 1 1 2 2 2 0 Mannitol dehydrogenase Rossmann domain KELK PF15796.5 KUM59908.1 - 0.53 10.8 13.0 0.78 10.2 6.4 2.9 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3450 PF11932.8 KUM59908.1 - 3.2 7.0 14.8 0.11 11.8 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Tup_N PF08581.10 KUM59908.1 - 4.6 7.6 14.2 7 7.0 5.4 3.8 1 1 3 4 4 4 0 Tup N-terminal Porph_ging PF09697.10 KUM59908.1 - 5.6 7.6 7.7 2.4 8.8 0.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (Porph_ging) DUF724 PF05266.14 KUM59908.1 - 5.7 6.7 16.4 0.16 11.8 5.1 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF724) Ribo_biogen_C PF04034.13 KUM59909.1 - 3.9e-50 168.8 0.0 5.6e-50 168.3 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KUM59909.1 - 2.7e-11 43.1 1.0 2.7e-11 43.1 1.0 1.6 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI NOA36 PF06524.12 KUM59909.1 - 2.2 7.5 16.8 3.9 6.7 16.8 1.3 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KUM59909.1 - 3.2 5.8 22.0 4.2 5.5 22.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KUM59909.1 - 6.8 6.0 23.1 9.8 5.5 23.1 1.2 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 KUM59909.1 - 6.9 6.3 20.2 12 5.6 20.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein VHS PF00790.19 KUM59910.1 - 2.6e-44 150.5 0.0 1e-43 148.6 0.0 2.0 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 KUM59910.1 - 4.5e-24 84.9 0.8 1.3e-23 83.4 0.8 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 KUM59910.1 - 5.7e-21 74.6 0.7 1.4e-20 73.3 0.1 2.1 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 KUM59910.1 - 2.4e-07 30.2 0.5 1.4e-06 27.8 0.1 2.4 2 0 0 2 2 2 1 GGA N-GAT domain Mei5 PF10376.9 KUM59910.1 - 0.048 13.5 2.3 0.088 12.7 2.3 1.4 1 0 0 1 1 1 0 Double-strand recombination repair protein DUF349 PF03993.12 KUM59910.1 - 6.5 7.1 6.1 0.94 9.8 0.8 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) AP3D1 PF06375.11 KUM59911.1 - 0.2 11.9 8.0 0.2 11.9 8.0 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Cadherin_tail PF15974.5 KUM59911.1 - 0.24 11.7 4.0 0.24 11.7 4.0 1.2 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region DUF4710 PF15828.5 KUM59911.1 - 0.51 10.5 12.4 0.64 10.2 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Peptidase_S49_N PF08496.10 KUM59911.1 - 2.7 8.0 7.7 3.2 7.8 7.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SHR3_chaperone PF08229.11 KUM59911.1 - 5.6 5.9 4.6 6.3 5.7 4.6 1.0 1 0 0 1 1 1 0 ER membrane protein SH3 CBS PF00571.28 KUM59913.1 - 1.8e-17 63.5 4.2 6.7e-06 26.5 0.0 5.2 5 0 0 5 5 5 4 CBS domain Epimerase PF01370.21 KUM59914.1 - 4.2e-14 52.6 0.0 8.1e-14 51.7 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM59914.1 - 1.9e-11 44.0 0.0 3.1e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KUM59914.1 - 8.8e-10 38.0 0.0 1.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KUM59914.1 - 4.2e-07 30.0 0.0 6.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KUM59914.1 - 1e-06 28.2 0.2 0.0019 17.4 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KUM59914.1 - 0.00011 21.8 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KUM59914.1 - 0.0055 15.9 0.0 0.0089 15.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KUM59914.1 - 0.14 12.1 1.7 2 8.3 1.7 2.3 1 1 0 1 1 1 0 KR domain DUF3543 PF12063.8 KUM59916.1 - 4.6e-92 307.9 0.0 7.1e-92 307.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KUM59916.1 - 1.9e-61 207.8 0.0 3.2e-61 207.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM59916.1 - 1.4e-42 145.7 0.0 2.4e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KUM59916.1 - 0.078 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase zf-C2H2 PF00096.26 KUM59917.1 - 4.1e-12 45.9 13.5 1.9e-06 28.0 0.4 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM59917.1 - 4.7e-08 33.2 10.0 0.0022 18.7 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KUM59917.1 - 7.9e-08 32.4 9.9 6.7e-07 29.4 4.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 KUM59917.1 - 4e-05 23.8 4.5 0.0067 16.8 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KUM59917.1 - 0.00016 21.6 9.2 0.0069 16.4 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KUM59917.1 - 0.00016 21.9 7.1 0.01 16.1 0.5 2.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KUM59917.1 - 0.0025 17.4 3.0 1.1 9.0 0.3 2.6 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 KUM59917.1 - 0.11 12.4 1.7 15 5.6 0.1 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-BED PF02892.15 KUM59917.1 - 0.13 12.3 5.4 0.052 13.6 1.5 2.1 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 KUM59917.1 - 0.46 10.9 3.5 7 7.0 0.4 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KUM59917.1 - 0.47 10.3 7.8 8.9 6.2 0.0 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 KUM59917.1 - 0.56 10.7 6.9 77 3.9 7.0 2.7 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Diphthami_syn_2 PF01902.17 KUM59918.1 - 6.5e-17 61.8 0.0 3.4e-11 43.1 0.0 3.4 2 1 0 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KUM59918.1 - 1.1e-15 57.8 0.1 1.8e-07 31.2 0.0 3.4 3 0 0 3 3 3 2 Endoribonuclease L-PSP DEAD PF00270.29 KUM59919.1 - 1e-46 158.9 0.0 3.6e-46 157.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM59919.1 - 9.1e-29 100.0 0.2 7e-28 97.2 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM59919.1 - 0.00033 20.7 0.0 0.00062 19.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2986 PF11661.8 KUM59919.1 - 0.03 14.8 3.4 0.1 13.1 3.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) DUF3334 PF11813.8 KUM59919.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) PRKG1_interact PF15898.5 KUM59919.1 - 5.9 7.9 9.5 16 6.5 0.1 3.4 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Suf PF05843.14 KUM59920.1 - 0.00052 20.1 4.6 0.0061 16.6 0.4 3.0 2 1 1 3 3 3 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KUM59920.1 - 0.014 16.1 6.1 25 6.0 0.0 6.8 7 1 2 9 9 9 0 Tetratricopeptide repeat HAT PF02184.16 KUM59920.1 - 0.96 9.5 19.0 2.3 8.2 0.3 6.2 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat AA_permease_2 PF13520.6 KUM59921.1 - 7.6e-91 305.0 39.7 9.3e-91 304.8 39.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM59921.1 - 3.4e-19 68.8 35.7 4.8e-19 68.3 35.7 1.2 1 0 0 1 1 1 1 Amino acid permease ERAP1_C PF11838.8 KUM59922.1 - 2.5e-90 303.3 0.0 2.2e-88 296.9 0.0 2.4 2 0 0 2 2 2 2 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KUM59922.1 - 4.2e-84 281.5 0.6 6.1e-84 280.9 0.6 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KUM59922.1 - 2.1e-56 191.0 1.0 3.4e-56 190.4 1.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 KUM59922.1 - 0.015 15.3 0.1 0.032 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Mitoc_mL59 PF18126.1 KUM59923.1 - 1.3e-45 154.8 3.7 1.6e-45 154.5 3.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 MOSC PF03473.17 KUM59924.1 - 4.8e-33 114.0 0.0 9.7e-33 113.0 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KUM59924.1 - 1.9e-26 92.3 0.0 3.6e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 KUM59924.1 - 2.5e-25 89.2 0.0 4.1e-25 88.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.19 KUM59925.1 - 2.1e-71 240.6 0.0 2.8e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain GST_C_6 PF17171.4 KUM59925.1 - 0.09 12.6 0.0 0.7 9.7 0.0 2.4 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 KUM59926.1 - 4.4e-45 154.1 54.1 6.3e-43 147.0 33.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM59926.1 - 9.8e-11 41.2 2.4 9.8e-11 41.2 2.4 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KUM59926.1 - 8.5e-05 21.2 3.7 8.5e-05 21.2 3.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF5536 PF17688.1 KUM59926.1 - 0.0091 15.9 0.0 0.027 14.4 0.0 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5536) TPR_2 PF07719.17 KUM59927.1 - 1.5e-09 37.2 9.5 0.16 12.1 0.0 6.1 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KUM59927.1 - 4.1e-06 26.4 1.2 4.8 7.2 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KUM59927.1 - 0.00011 21.6 0.4 0.00054 19.4 0.1 2.1 2 0 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 KUM59927.1 - 0.00027 20.7 1.3 3.2 8.0 0.2 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KUM59927.1 - 0.0025 18.5 8.1 5.8 8.0 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 KUM59927.1 - 0.0028 18.1 10.3 0.5 11.2 0.8 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KUM59927.1 - 0.0053 17.4 14.3 2 9.1 0.7 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 KUM59927.1 - 0.0074 16.6 7.2 0.01 16.1 0.4 4.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KUM59927.1 - 0.33 11.3 6.6 6.4 7.3 0.0 4.9 7 0 0 7 7 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KUM59927.1 - 0.85 9.4 6.4 22 4.8 0.0 4.8 5 0 0 5 5 5 0 TPR repeat TPR_10 PF13374.6 KUM59927.1 - 1.4 8.9 6.6 4.8 7.2 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_hydro_28 PF00295.17 KUM59928.1 - 7.7e-55 186.2 6.6 1.1e-54 185.7 6.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF4528 PF15031.6 KUM59928.1 - 0.035 14.1 0.0 0.08 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) MAPEG PF01124.18 KUM59929.1 - 4.1e-14 52.6 2.0 5.8e-14 52.1 2.0 1.2 1 0 0 1 1 1 1 MAPEG family p450 PF00067.22 KUM59930.1 - 1e-72 245.4 0.0 1.3e-72 245.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KUM59931.1 - 4.1e-31 108.2 29.4 4.1e-31 108.2 29.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM59931.1 - 4.6e-10 38.9 8.8 4.6e-10 38.9 8.8 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KUM59931.1 - 1.4e-07 30.4 3.0 2.5e-07 29.5 3.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_M48_N PF16491.5 KUM59931.1 - 7.1 6.5 8.0 26 4.7 2.7 3.2 3 0 0 3 3 3 0 CAAX prenyl protease N-terminal, five membrane helices Abhydrolase_3 PF07859.13 KUM59932.1 - 1.7e-21 77.1 0.0 2.4e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KUM59932.1 - 1.8e-15 56.7 0.0 2.6e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KUM59932.1 - 0.038 13.5 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family adh_short PF00106.25 KUM59933.1 - 1.2e-38 132.5 0.3 2e-38 131.8 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM59933.1 - 1.1e-25 90.6 0.0 1.6e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM59933.1 - 8.8e-07 29.0 1.9 2.5e-05 24.3 1.9 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM59933.1 - 0.00044 19.8 0.1 0.00068 19.2 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KUM59933.1 - 0.077 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UPF0146 PF03686.13 KUM59933.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Lipase_3 PF01764.25 KUM59934.1 - 3.1e-30 104.9 0.0 4.5e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KUM59934.1 - 0.00051 19.4 0.0 0.00078 18.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KUM59934.1 - 0.006 16.1 0.0 0.0092 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KUM59934.1 - 0.011 16.3 0.1 0.015 15.9 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase3_N PF03893.16 KUM59934.1 - 0.026 14.6 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipase 3 N-terminal region PGAP1 PF07819.13 KUM59934.1 - 0.12 12.0 0.1 0.61 9.8 0.0 2.0 2 1 0 2 2 2 0 PGAP1-like protein FMO-like PF00743.19 KUM59935.1 - 3.6e-16 58.7 0.0 3.5e-15 55.4 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KUM59935.1 - 1.4e-12 47.5 0.1 2.5e-11 43.4 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM59935.1 - 5.5e-11 42.5 0.0 5.1e-08 33.0 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM59935.1 - 1.7e-10 40.6 0.0 4.3e-07 29.5 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KUM59935.1 - 1.1e-07 31.4 0.0 5.8e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KUM59935.1 - 1.3e-06 28.3 0.1 0.0011 18.6 0.2 3.8 4 1 0 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KUM59935.1 - 3.6e-06 26.4 0.0 0.00046 19.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KUM59935.1 - 3.4e-05 24.3 0.0 0.0096 16.5 0.0 3.1 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KUM59935.1 - 0.00039 19.6 0.0 0.1 11.6 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein Shikimate_DH PF01488.20 KUM59935.1 - 0.001 19.1 0.0 0.023 14.8 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KUM59935.1 - 0.0012 18.8 0.2 1.3 9.0 0.0 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KUM59935.1 - 0.016 14.6 0.3 0.3 10.4 0.0 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 KUM59935.1 - 0.02 14.0 0.3 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KUM59935.1 - 0.035 13.2 0.1 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 KUM59935.1 - 0.065 13.7 0.0 0.18 12.2 0.0 1.8 2 0 0 2 2 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 KUM59935.1 - 0.19 10.6 0.1 5.8 5.6 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 KUM59935.1 - 0.37 9.5 0.5 2.6 6.7 0.0 2.2 3 0 0 3 3 3 0 HI0933-like protein PTR2 PF00854.21 KUM59936.1 - 1.3e-81 274.4 8.7 1.8e-81 274.0 8.7 1.1 1 0 0 1 1 1 1 POT family DUF1115 PF06544.12 KUM59938.1 - 0.049 13.7 0.0 0.13 12.4 0.0 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1115) Fungal_trans PF04082.18 KUM59939.1 - 2.1e-19 69.6 0.1 4.4e-19 68.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 KUM59940.1 - 4.7e-72 241.8 53.6 1.1e-38 132.8 26.0 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KUM59940.1 - 2e-36 125.5 0.0 6.6e-17 62.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KUM59940.1 - 2.8e-23 81.6 0.3 2.8e-23 81.6 0.3 3.4 4 0 0 4 4 2 2 CDR ABC transporter AAA_16 PF13191.6 KUM59940.1 - 4.7e-07 30.4 0.2 7.7e-05 23.1 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 KUM59940.1 - 7.1e-07 28.6 37.4 0.00011 21.5 16.0 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KUM59940.1 - 5.5e-05 23.1 0.1 0.0042 17.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KUM59940.1 - 8.2e-05 22.7 0.0 0.029 14.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KUM59940.1 - 0.0001 22.0 1.4 0.0083 15.8 0.3 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KUM59940.1 - 0.00017 21.5 0.4 0.12 12.1 0.5 2.8 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KUM59940.1 - 0.00035 20.2 0.4 0.038 13.6 0.1 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KUM59940.1 - 0.00099 19.4 0.3 0.2 11.9 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 KUM59940.1 - 0.0012 19.4 0.0 0.0099 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KUM59940.1 - 0.0061 16.3 0.5 1.6 8.4 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KUM59940.1 - 0.0094 16.1 0.0 0.31 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KUM59940.1 - 0.052 12.9 0.1 12 5.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 KUM59940.1 - 0.06 13.9 0.5 0.14 12.7 0.5 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KUM59940.1 - 0.073 13.3 0.3 0.23 11.7 0.3 1.9 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KUM59940.1 - 0.12 11.8 0.0 14 5.0 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Ploopntkinase3 PF18751.1 KUM59940.1 - 0.21 11.5 0.4 1.3 8.9 0.1 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 KUM59940.1 - 0.37 10.0 1.2 4.8 6.4 0.3 2.7 3 0 0 3 3 3 0 Zeta toxin PALP PF00291.25 KUM59941.1 - 2.3e-62 211.1 0.4 2.6e-62 210.9 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3343 PF11823.8 KUM59941.1 - 0.17 11.3 0.2 0.86 9.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3343) Isochorismatase PF00857.20 KUM59942.1 - 3.4e-40 138.1 0.1 3.8e-40 137.9 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family MTBP_mid PF14919.6 KUM59942.1 - 0.21 10.7 0.0 0.24 10.6 0.0 1.0 1 0 0 1 1 1 0 MDM2-binding Ribonuc_L-PSP PF01042.21 KUM59943.1 - 6e-16 58.5 0.0 7.2e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Mannosyl_trans3 PF11051.8 KUM59945.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_transf_8 PF01501.20 KUM59945.1 - 0.19 11.3 2.5 0.54 9.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 8 PfkB PF00294.24 KUM59946.1 - 8.3e-37 127.1 0.4 9.7e-37 126.9 0.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PARP PF00644.20 KUM59947.1 - 1.3e-58 197.8 1.3 4.2e-58 196.2 0.0 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KUM59947.1 - 1.2e-40 138.8 0.1 2.3e-40 137.9 0.1 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KUM59947.1 - 1.8e-18 66.4 0.3 1.8e-18 66.4 0.3 2.4 2 0 0 2 2 2 1 WGR domain PTCB-BRCT PF12738.7 KUM59947.1 - 7.6e-07 29.0 0.1 1.7e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KUM59947.1 - 1.4e-06 28.6 0.1 3.6e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KUM59947.1 - 0.00012 22.4 0.0 0.0003 21.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Fungal_trans_2 PF11951.8 KUM59948.1 - 6.2e-11 41.7 0.1 1.5e-10 40.5 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM59949.1 - 1.2e-09 38.2 9.4 1.8e-09 37.6 9.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ARL6IP6 PF15062.6 KUM59949.1 - 0.15 12.2 0.1 6.3 7.0 0.1 2.4 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Sugar_tr PF00083.24 KUM59951.1 - 9.4e-108 361.0 30.7 2.1e-107 359.8 30.7 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM59951.1 - 2.2e-20 72.9 91.1 2.9e-18 65.9 52.4 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 KUM59951.1 - 0.23 9.7 9.6 0.042 12.1 5.0 1.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TFIIF_beta_N PF17683.1 KUM59952.1 - 1.6e-29 103.3 0.0 3.1e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 KUM59952.1 - 6.3e-28 96.7 0.3 1e-27 96.1 0.3 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 KUM59952.1 - 0.0023 18.8 0.4 0.0041 17.9 0.4 1.6 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain MFS_1 PF07690.16 KUM59953.1 - 6.5e-39 133.8 38.6 1.1e-38 133.1 38.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM59953.1 - 6.6e-06 25.3 12.9 6.6e-06 25.3 12.9 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter Patatin PF01734.22 KUM59954.1 - 0.00016 21.9 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Tn7_Tnp_TnsA_C PF08721.11 KUM59954.1 - 0.055 14.1 0.0 16 6.2 0.0 2.4 2 0 0 2 2 2 0 TnsA endonuclease C terminal DUF3603 PF12227.8 KUM59954.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) DUF2451 PF10474.9 KUM59954.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) NAD_binding_4 PF07993.12 KUM59955.1 - 2.4e-31 108.9 0.0 3.2e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 KUM59956.1 - 4.4e-59 200.6 0.0 6.8e-59 199.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KUM59956.1 - 5.4e-59 199.9 0.0 8.6e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KUM59956.1 - 3e-58 196.7 0.3 5.6e-58 195.8 0.3 1.5 1 0 0 1 1 1 1 KR domain KAsynt_C_assoc PF16197.5 KUM59956.1 - 2.3e-26 92.5 0.0 7e-26 90.9 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Ketoacyl-synt_C PF02801.22 KUM59956.1 - 4.5e-26 91.2 0.4 1.3e-25 89.7 0.4 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KUM59956.1 - 2.4e-18 66.7 0.0 7.6e-18 65.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KUM59956.1 - 1.5e-14 55.2 0.0 9.3e-14 52.6 0.0 2.5 3 0 0 3 3 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KUM59956.1 - 1.5e-14 54.1 0.9 5.7e-14 52.2 0.0 2.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KUM59956.1 - 6.2e-12 46.1 0.0 2.3e-11 44.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM59956.1 - 1.1e-11 45.2 0.0 4.5e-11 43.2 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM59956.1 - 1.2e-11 44.8 0.0 3e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KUM59956.1 - 2.4e-11 43.5 0.5 9.6e-10 38.2 0.1 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_31 PF13847.6 KUM59956.1 - 3.6e-08 33.3 0.0 7.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM59956.1 - 6e-06 25.8 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 KUM59956.1 - 2.7e-05 24.4 0.0 0.0001 22.6 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.12 KUM59956.1 - 3.6e-05 23.6 0.2 0.00013 21.8 0.2 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 KUM59956.1 - 7.3e-05 22.4 0.4 0.00018 21.2 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.26 KUM59956.1 - 0.00019 21.1 0.0 0.00047 19.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_24 PF13578.6 KUM59956.1 - 0.0033 18.4 0.1 0.031 15.3 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 KUM59956.1 - 0.0046 16.7 0.2 0.022 14.5 0.0 2.1 3 0 0 3 3 2 1 Lysine methyltransferase bZIP_1 PF00170.21 KUM59957.1 - 0.00014 21.8 21.2 0.11 12.6 21.2 2.8 1 1 0 1 1 1 1 bZIP transcription factor DUF812 PF05667.11 KUM59957.1 - 0.038 12.9 21.2 0.01 14.8 15.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) bZIP_2 PF07716.15 KUM59957.1 - 0.042 13.9 22.2 0.38 10.9 13.2 2.8 1 1 1 2 2 2 0 Basic region leucine zipper DUF3450 PF11932.8 KUM59957.1 - 0.078 12.3 15.6 0.092 12.0 14.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_Maf PF03131.17 KUM59957.1 - 1 9.9 22.3 0.098 13.2 14.5 2.8 1 1 1 2 2 2 0 bZIP Maf transcription factor V_ATPase_I PF01496.19 KUM59957.1 - 5.4 4.8 12.6 9.8 3.9 12.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-CCCH PF00642.24 KUM59958.1 - 2.7e-16 59.0 30.9 1.6e-05 24.7 1.3 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KUM59958.1 - 3.8e-11 42.7 30.9 0.0063 16.5 0.8 6.1 5 1 0 5 5 5 5 Zinc finger domain zf-CCCH_3 PF15663.5 KUM59958.1 - 0.0001 22.5 17.8 0.0016 18.7 1.9 3.7 1 1 2 3 3 3 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KUM59958.1 - 0.00017 21.3 23.3 0.033 14.0 0.0 5.2 5 1 0 5 5 5 2 CCCH-type zinc finger Torus PF16131.5 KUM59958.1 - 0.011 16.4 28.3 0.26 12.0 0.9 4.9 2 1 3 5 5 5 0 Torus domain zf-C3H1 PF10650.9 KUM59958.1 - 0.055 13.2 0.3 0.055 13.2 0.3 4.4 5 0 0 5 5 5 0 Putative zinc-finger domain Ebp2 PF05890.12 KUM59958.1 - 0.17 11.4 4.9 0.31 10.6 4.9 1.3 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 FXMRP1_C_core PF12235.8 KUM59958.1 - 1.7 9.3 6.4 6.6 7.4 6.3 2.1 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal BTB PF00651.31 KUM59959.1 - 0.001 19.3 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Zip PF02535.22 KUM59960.1 - 3.9e-55 187.4 0.6 5.3e-55 187.0 0.6 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter HXXEE PF13787.6 KUM59960.1 - 6.7 7.6 7.3 5.1 7.9 1.0 2.8 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif Ala_racemase_N PF01168.20 KUM59961.1 - 1.3e-28 100.2 0.0 1.5e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 KUM59961.1 - 1.8e-20 73.4 0.0 4.5e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain SDH_alpha PF03313.15 KUM59961.1 - 0.044 13.4 0.2 0.99 9.0 0.1 2.2 2 0 0 2 2 2 0 Serine dehydratase alpha chain Glyco_hydro_16 PF00722.21 KUM59962.1 - 7.3e-08 32.1 0.1 1.4e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Zn_clus PF00172.18 KUM59963.1 - 0.00019 21.5 11.4 0.00019 21.5 11.4 2.4 1 1 1 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KUM59964.1 - 2.2e-64 218.0 0.0 2.6e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_28 PF03033.20 KUM59965.1 - 1.7e-23 83.2 0.0 3.2e-23 82.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Transferase PF02458.15 KUM59966.1 - 2.8e-34 118.5 0.0 3.9e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Transferase family Condensation PF00668.20 KUM59966.1 - 0.0005 18.9 0.0 0.00076 18.3 0.0 1.1 1 0 0 1 1 1 1 Condensation domain MFS_1 PF07690.16 KUM59968.1 - 3.1e-18 65.8 43.1 2.8e-17 62.7 36.8 3.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM59968.1 - 1.2e-14 53.6 12.4 2.2e-14 52.9 12.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3176 PF11374.8 KUM59968.1 - 0.94 9.7 9.6 7.2 6.9 0.3 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3176) DAO PF01266.24 KUM59970.1 - 3.8e-20 72.8 0.0 4.4e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KUM59970.1 - 0.0024 17.2 0.0 0.0042 16.3 0.0 1.4 1 1 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KUM59970.1 - 0.0024 18.1 0.1 0.0041 17.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KUM59970.1 - 0.0062 16.5 0.1 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KUM59970.1 - 0.1 11.6 0.1 0.28 10.2 0.0 1.7 1 1 1 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KUM59970.1 - 0.1 11.8 0.0 0.13 11.4 0.0 1.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM59970.1 - 0.13 12.8 0.0 0.53 10.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KUM59970.1 - 0.14 12.6 0.0 0.35 11.3 0.0 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding ATG_C PF09333.11 KUM59971.1 - 0.00083 19.7 0.0 0.023 15.0 0.0 2.8 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 KUM59971.1 - 0.023 14.5 0.1 0.059 13.1 0.1 1.6 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal UDPGT PF00201.18 KUM59971.1 - 0.038 12.8 0.0 0.057 12.2 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase ABC_tran PF00005.27 KUM59972.1 - 1.8e-42 145.1 0.0 1.3e-21 77.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KUM59972.1 - 8.6e-28 97.8 24.0 1e-25 90.9 11.4 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KUM59972.1 - 7.4e-11 41.9 0.7 0.005 16.3 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KUM59972.1 - 1.5e-07 32.0 1.9 0.03 14.7 0.1 3.4 4 0 0 4 4 3 2 AAA ATPase domain AAA_21 PF13304.6 KUM59972.1 - 1.8e-07 31.3 6.2 0.13 12.1 0.1 4.3 2 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KUM59972.1 - 4e-07 30.4 0.1 0.014 15.7 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KUM59972.1 - 7.6e-07 28.8 0.4 0.014 15.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KUM59972.1 - 1.9e-05 23.9 0.2 0.0094 15.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KUM59972.1 - 4.5e-05 23.5 0.2 0.1 12.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 KUM59972.1 - 9.8e-05 22.8 0.0 0.098 13.1 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KUM59972.1 - 0.00012 22.6 0.3 0.65 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KUM59972.1 - 0.00013 22.5 0.1 0.13 12.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KUM59972.1 - 0.00014 22.1 1.1 0.0015 18.6 0.0 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 KUM59972.1 - 0.00014 21.8 0.2 0.41 10.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KUM59972.1 - 0.00056 19.5 0.1 0.73 9.3 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region cobW PF02492.19 KUM59972.1 - 0.00077 19.1 0.5 0.085 12.4 0.4 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 KUM59972.1 - 0.001 18.8 0.0 0.47 10.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 KUM59972.1 - 0.0035 17.6 1.0 1.8 8.8 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 KUM59972.1 - 0.0047 16.5 0.3 0.32 10.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 KUM59972.1 - 0.0047 17.0 0.2 2.8 8.0 0.1 2.5 2 0 0 2 2 2 1 Dynamin family ATP_bind_1 PF03029.17 KUM59972.1 - 0.0056 16.5 0.3 0.12 12.1 0.2 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 KUM59972.1 - 0.0072 16.5 3.2 0.23 11.6 0.2 3.0 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KUM59972.1 - 0.011 15.5 0.1 11 5.6 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein PduV-EutP PF10662.9 KUM59972.1 - 0.011 15.5 0.6 0.093 12.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.18 KUM59972.1 - 0.012 15.0 0.1 1 8.6 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 KUM59972.1 - 0.017 15.1 0.0 3.4 7.6 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 KUM59972.1 - 0.017 14.4 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 KUM59972.1 - 0.029 14.4 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KUM59972.1 - 0.04 14.3 0.0 16 6.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Adeno_IVa2 PF02456.15 KUM59972.1 - 0.041 12.7 0.4 0.74 8.5 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_30 PF13604.6 KUM59972.1 - 0.043 13.5 0.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 KUM59972.1 - 0.058 12.9 0.2 9.6 5.7 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_5 PF07728.14 KUM59972.1 - 0.061 13.3 0.4 17 5.4 0.1 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KUM59972.1 - 0.087 12.2 0.7 12 5.2 0.0 2.5 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KUM59972.1 - 0.18 11.5 0.1 12 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KUM59972.1 - 0.62 9.9 4.4 5 7.0 0.2 2.9 3 0 0 3 3 3 0 NTPase NB-ARC PF00931.22 KUM59972.1 - 1.4 8.0 2.9 26 3.9 0.9 3.0 2 1 0 2 2 2 0 NB-ARC domain adh_short PF00106.25 KUM59974.1 - 3.6e-16 59.2 0.0 6.7e-15 55.1 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KUM59974.1 - 1.8e-09 37.8 0.0 3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KUM59974.1 - 1.1e-08 35.0 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase EcKinase PF02958.20 KUM59974.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.4 2 0 0 2 2 2 0 Ecdysteroid kinase 2OG-FeII_Oxy_2 PF13532.6 KUM59975.1 - 4.5e-16 59.6 0.0 5.4e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KUM59975.1 - 0.004 17.6 0.0 0.0085 16.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Epimerase PF01370.21 KUM59977.1 - 4.3e-14 52.5 0.0 6.4e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KUM59977.1 - 3.8e-06 26.9 0.4 3.4e-05 23.8 0.1 2.4 2 1 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KUM59977.1 - 9.9e-05 21.5 0.0 0.00015 20.8 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KUM59977.1 - 0.00027 20.5 0.1 0.00043 19.8 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KUM59977.1 - 0.0012 18.5 0.1 0.0018 17.8 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KUM59977.1 - 0.0033 16.6 0.1 0.0053 15.9 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 KUM59977.1 - 0.013 15.1 0.1 0.026 14.1 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RmlD_sub_bind PF04321.17 KUM59977.1 - 0.12 11.4 0.6 0.69 9.0 0.0 2.2 3 0 0 3 3 3 0 RmlD substrate binding domain DAO PF01266.24 KUM59979.1 - 1.7e-06 27.8 0.2 1.9e-06 27.7 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Peptidase_M22 PF00814.25 KUM59980.1 - 0.00068 19.4 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Glycoprotease family Podoplanin PF05808.11 KUM59980.1 - 0.0016 18.5 1.4 0.0029 17.7 1.4 1.3 1 0 0 1 1 1 1 Podoplanin Glycophorin_A PF01102.18 KUM59980.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A DUF4690 PF15756.5 KUM59980.1 - 0.03 14.9 0.4 0.081 13.5 0.4 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF2207 PF09972.9 KUM59980.1 - 0.047 12.5 0.0 0.14 10.9 0.0 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Amnionless PF14828.6 KUM59980.1 - 0.053 12.3 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF1735 PF08522.10 KUM59980.1 - 0.065 13.8 0.4 0.065 13.8 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1735) p450 PF00067.22 KUM59982.1 - 1.4e-21 76.8 0.0 3.2e-21 75.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Acyltransferase PF01553.21 KUM59984.1 - 4.4e-30 104.1 0.0 7.4e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ACC_central PF08326.12 KUM59985.1 - 4.6e-279 927.7 0.0 6e-279 927.3 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KUM59985.1 - 9e-191 634.8 0.0 1.9e-190 633.8 0.0 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KUM59985.1 - 3.6e-53 180.2 0.0 7.4e-53 179.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KUM59985.1 - 4.8e-28 97.9 0.1 9.7e-28 96.9 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KUM59985.1 - 5.7e-24 84.3 0.0 9.8e-20 70.7 0.0 3.7 4 0 0 4 4 4 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KUM59985.1 - 4.4e-17 61.7 0.1 1.2e-16 60.3 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KUM59985.1 - 3.5e-05 23.4 0.0 0.00011 21.9 0.0 1.8 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KUM59985.1 - 9.1e-05 22.6 0.0 0.00035 20.6 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain GxGYxYP_N PF16216.5 KUM59985.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal ATP-grasp PF02222.22 KUM59985.1 - 0.034 13.7 0.0 0.081 12.5 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_Ter PF15632.6 KUM59985.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon CorA PF01544.18 KUM59987.1 - 0.066 12.5 1.1 0.16 11.3 1.1 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2884 PF11101.8 KUM59987.1 - 0.65 9.5 10.0 2.5 7.6 0.3 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2884) HeLo PF14479.6 KUM59988.1 - 0.00011 22.1 0.5 0.0064 16.4 0.5 2.4 1 1 0 1 1 1 1 Prion-inhibition and propagation Peptidase_S64 PF08192.11 KUM59988.1 - 0.068 11.7 0.1 0.16 10.5 0.0 1.5 2 0 0 2 2 2 0 Peptidase family S64 RINGv PF12906.7 KUM59989.1 - 7.5e-16 58.0 10.1 1.3e-15 57.2 10.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KUM59989.1 - 0.16 12.3 10.1 0.28 11.5 10.1 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 KUM59989.1 - 0.27 11.1 6.2 0.45 10.3 6.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KUM59989.1 - 1.9 8.7 6.3 3.7 7.8 6.3 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain DUF3742 PF12553.8 KUM59989.1 - 3.1 7.9 8.5 6.9 6.8 0.4 4.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) zf-C3HC4_3 PF13920.6 KUM59989.1 - 3.6 7.5 5.9 7.9 6.4 5.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) F-box-like PF12937.7 KUM59993.1 - 3.4e-07 30.0 0.1 1.4e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KUM59993.1 - 0.0068 16.3 0.1 0.046 13.6 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KUM59993.1 - 0.16 11.8 0.0 0.85 9.5 0.0 2.0 1 1 1 2 2 2 0 F-box TMEM208_SND2 PF05620.11 KUM59994.1 - 7e-57 191.9 0.0 7.8e-57 191.7 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 TPR_1 PF00515.28 KUM59995.1 - 1.3e-44 148.2 21.2 4.8e-08 32.5 0.0 9.7 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 KUM59995.1 - 5.1e-41 135.5 21.1 1.8e-05 24.5 0.3 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM59995.1 - 3.2e-31 107.4 18.9 1.2e-22 79.9 1.4 4.4 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KUM59995.1 - 5.5e-27 91.7 10.3 0.0011 19.0 0.0 9.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 KUM59995.1 - 2.1e-22 78.5 10.9 4e-05 23.2 2.5 9.2 7 3 2 9 9 9 5 TPR repeat TPR_19 PF14559.6 KUM59995.1 - 1.1e-20 73.9 18.3 2.1e-08 34.5 0.3 8.4 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 KUM59995.1 - 9.4e-20 71.0 23.2 0.00078 20.0 0.2 8.2 6 2 2 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 KUM59995.1 - 5.4e-19 67.3 9.1 0.04 14.7 0.0 9.1 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 KUM59995.1 - 4.3e-16 59.0 16.2 0.021 15.1 0.4 7.8 5 1 4 9 9 9 6 Tetratricopeptide repeat TPR_7 PF13176.6 KUM59995.1 - 2.6e-12 45.8 4.1 0.0015 18.4 0.0 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KUM59995.1 - 4.2e-12 45.6 13.0 0.064 13.7 0.0 8.2 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 KUM59995.1 - 2.9e-10 40.1 5.3 0.51 11.1 0.1 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KUM59995.1 - 6.4e-05 22.7 0.1 22 5.1 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 KUM59995.1 - 0.00018 21.6 3.8 2.9 8.1 0.1 5.4 3 1 2 6 6 6 1 Tetratricopeptide repeat TPR_21 PF09976.9 KUM59995.1 - 0.016 14.9 9.2 0.19 11.4 1.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain Sel1 PF08238.12 KUM59995.1 - 0.075 13.7 1.1 23 5.8 0.0 5.1 6 0 0 6 6 5 0 Sel1 repeat CCP_MauG PF03150.14 KUM59995.1 - 0.087 13.5 0.1 0.46 11.1 0.1 2.2 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase ChAPs PF09295.10 KUM59995.1 - 0.19 10.7 1.2 11 4.8 0.1 2.4 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) APP_E2 PF12925.7 KUM59995.1 - 0.53 10.0 2.0 0.77 9.4 0.2 2.2 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein MIT PF04212.18 KUM59995.1 - 4.4 7.4 5.9 13 5.9 0.4 4.2 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain DUF2225 PF09986.9 KUM59995.1 - 7.2 6.3 11.6 3.8 7.2 0.1 4.0 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) MFS_1 PF07690.16 KUM59997.1 - 3.1e-31 108.6 65.7 2.4e-30 105.7 61.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3333 PF11812.8 KUM59998.1 - 0.32 11.2 0.6 0.45 10.7 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) NUDE_C PF04880.13 KUM60000.1 - 8.9e-66 221.7 6.5 8.9e-66 221.7 6.5 4.5 2 1 4 6 6 2 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 KUM60000.1 - 0.008 16.6 6.9 0.008 16.6 6.9 4.7 2 1 2 4 4 4 1 Cell division protein ZapB PSII_Pbs27 PF13326.6 KUM60000.1 - 0.12 12.7 4.0 0.29 11.5 4.0 1.7 1 0 0 1 1 1 0 Photosystem II Pbs27 TPR_MLP1_2 PF07926.12 KUM60000.1 - 0.13 12.3 30.3 0.23 11.5 9.4 3.9 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein ERM PF00769.19 KUM60000.1 - 0.28 11.0 28.6 0.61 9.9 28.6 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ADIP PF11559.8 KUM60000.1 - 0.5 10.4 29.7 0.81 9.8 3.1 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF745 PF05335.13 KUM60000.1 - 0.58 9.8 9.7 1.1 9.0 9.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Filament PF00038.21 KUM60000.1 - 0.64 9.6 28.4 1.6 8.3 12.3 2.5 1 1 1 2 2 2 0 Intermediate filament protein Tho2 PF11262.8 KUM60000.1 - 0.94 8.6 18.7 0.1 11.8 1.9 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF4201 PF13870.6 KUM60000.1 - 0.98 9.1 23.7 0.11 12.2 1.8 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Fez1 PF06818.15 KUM60000.1 - 1 9.8 25.1 2.3 8.6 9.6 2.9 2 1 1 3 3 3 0 Fez1 APG6_N PF17675.1 KUM60000.1 - 1.1 9.8 37.6 0.16 12.5 8.0 3.3 1 1 2 3 3 3 0 Apg6 coiled-coil region PRKG1_interact PF15898.5 KUM60000.1 - 1.9 9.4 26.5 81 4.2 14.9 3.2 2 1 1 3 3 2 0 cGMP-dependent protein kinase interacting domain Chibby PF14645.6 KUM60000.1 - 3.6 8.0 12.8 30 5.1 7.4 3.0 1 1 1 2 2 2 0 Chibby family CENP-F_leu_zip PF10473.9 KUM60000.1 - 4.2 7.4 31.1 11 6.1 18.2 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IFT57 PF10498.9 KUM60000.1 - 4.4 6.2 19.6 0.52 9.2 14.7 1.7 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Cep57_MT_bd PF06657.13 KUM60000.1 - 5.7 7.5 21.5 0.73 10.3 6.5 3.9 2 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF812 PF05667.11 KUM60000.1 - 6.4 5.5 24.3 11 4.7 24.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) AAA_13 PF13166.6 KUM60000.1 - 7.1 5.1 17.8 11 4.4 17.8 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 KUM60000.1 - 7.7 5.3 29.2 0.27 10.1 18.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Isochorismatase PF00857.20 KUM60002.1 - 4.1e-45 154.1 0.0 5.5e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Catalase_C PF18011.1 KUM60002.1 - 0.093 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain found in long catalases GMC_oxred_N PF00732.19 KUM60003.1 - 3.5e-69 233.4 0.0 5.7e-69 232.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM60003.1 - 1.4e-28 100.2 0.0 2.5e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KUM60003.1 - 3.7e-06 26.2 0.1 5.6e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KUM60003.1 - 9.3e-05 22.6 0.1 0.00037 20.7 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM60003.1 - 0.00015 21.5 0.0 0.00052 19.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KUM60003.1 - 0.00027 20.2 0.0 0.0029 16.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KUM60003.1 - 0.0023 17.2 0.0 0.0046 16.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KUM60003.1 - 0.011 15.0 0.1 0.045 13.0 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM60003.1 - 0.013 14.7 0.2 0.16 11.2 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KUM60003.1 - 0.045 12.4 0.0 0.088 11.5 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein Acetyltransf_1 PF00583.25 KUM60005.1 - 5.9e-09 36.2 0.0 1.1e-08 35.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KUM60005.1 - 2.5e-06 27.5 0.0 0.044 13.7 0.0 2.7 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 KUM60005.1 - 4.9e-06 27.2 0.0 9.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KUM60005.1 - 1.8e-05 25.0 0.0 4e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KUM60005.1 - 9.2e-05 22.5 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KUM60005.1 - 0.011 15.6 0.1 0.36 10.8 0.1 2.4 1 1 0 1 1 1 0 FR47-like protein FYVE PF01363.21 KUM60006.1 - 7.6e-15 54.8 7.8 1.2e-14 54.2 7.8 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 KUM60006.1 - 0.029 14.5 9.8 0.057 13.6 9.8 1.4 1 0 0 1 1 1 0 AN1-like Zinc finger 2-Hacid_dh_C PF02826.19 KUM60007.1 - 4.1e-52 176.1 0.0 5.9e-52 175.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KUM60007.1 - 6.9e-29 100.2 0.0 8.1e-29 100.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 KUM60007.1 - 0.0092 15.3 0.2 0.67 9.2 0.2 2.3 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KUM60007.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glycos_transf_1 PF00534.20 KUM60008.1 - 8.1e-35 119.9 0.0 1.2e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KUM60008.1 - 1.1e-29 103.6 0.0 1.8e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KUM60008.1 - 5.6e-11 42.7 0.2 4.1e-10 39.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KUM60008.1 - 1.4e-08 35.3 0.5 3.7e-08 34.0 0.0 2.0 2 1 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KUM60008.1 - 1.4e-08 35.0 0.0 3.3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 GST_N PF02798.20 KUM60009.1 - 2.3e-13 50.3 0.1 3.4e-12 46.5 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KUM60009.1 - 9.8e-10 38.7 0.1 4e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KUM60009.1 - 1.6e-09 37.9 0.0 3.6e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KUM60009.1 - 4.6e-06 26.5 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KUM60009.1 - 7.4e-06 26.1 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NDUF_B4 PF07225.12 KUM60009.1 - 0.00013 21.8 0.1 0.00035 20.5 0.0 1.7 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) GST_C PF00043.25 KUM60009.1 - 0.00033 20.8 0.0 0.00066 19.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KUM60009.1 - 0.085 13.4 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SAP18 PF06487.12 KUM60010.1 - 3.7e-46 156.8 0.0 4.5e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.15 KUM60011.1 - 5.7e-55 185.3 0.0 5.7e-55 185.3 0.0 1.9 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KUM60011.1 - 1.1e-09 37.7 2.3 1.1e-09 37.7 2.3 2.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like CDC27 PF09507.10 KUM60011.1 - 0.35 10.2 17.9 0.51 9.7 17.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HD PF01966.22 KUM60012.1 - 6.1e-07 29.7 0.0 9.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 HD domain Methyltr_RsmB-F PF01189.17 KUM60013.1 - 7.6e-16 58.3 0.0 1.8e-09 37.5 0.0 2.8 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F Ppx-GppA PF02541.16 KUM60014.1 - 4.2e-41 141.2 0.0 1.1e-40 139.8 0.0 1.6 1 1 0 1 1 1 1 Ppx/GppA phosphatase family Ferrochelatase PF00762.19 KUM60014.1 - 0.058 12.5 0.2 0.1 11.7 0.2 1.3 1 0 0 1 1 1 0 Ferrochelatase DUF3578 PF12102.8 KUM60014.1 - 0.13 11.9 0.0 0.71 9.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3578) Ferric_reduct PF01794.19 KUM60015.1 - 1.5e-22 80.1 16.0 2.6e-22 79.3 16.0 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KUM60015.1 - 1e-11 44.9 0.0 0.00014 21.9 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 KUM60015.1 - 1.2e-10 41.8 0.0 2.5e-06 27.7 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KUM60015.1 - 0.022 15.4 0.0 0.047 14.3 0.0 1.6 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain TcpE PF12648.7 KUM60015.1 - 3.5 8.2 5.8 6.9 7.3 5.4 1.7 1 1 0 1 1 1 0 TcpE family BNR_2 PF13088.6 KUM60016.1 - 1.2e-07 31.4 0.2 4.8e-07 29.4 0.2 1.9 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KUM60016.1 - 0.00047 19.7 6.5 0.14 12.3 0.6 4.2 3 0 0 3 3 3 2 BNR/Asp-box repeat BTB_2 PF02214.22 KUM60017.1 - 7.5e-09 35.8 0.2 3.2e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 KUM60017.1 - 0.041 14.1 0.0 4.3 7.6 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain OPT PF03169.15 KUM60018.1 - 7.9e-156 520.2 48.0 9.1e-156 520.0 48.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CcmD PF04995.14 KUM60018.1 - 0.018 15.1 0.2 0.018 15.1 0.2 3.2 4 0 0 4 4 4 0 Heme exporter protein D (CcmD) Pyr_redox_2 PF07992.14 KUM60019.1 - 6.8e-28 97.7 0.0 9.2e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM60019.1 - 5.5e-15 55.7 0.1 3.3e-12 46.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM60019.1 - 6.9e-05 22.1 0.0 0.00019 20.7 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KUM60019.1 - 0.0021 17.7 1.7 0.41 10.2 0.1 2.9 3 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KUM60019.1 - 0.0031 16.8 0.0 0.059 12.6 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NaeI PF09126.10 KUM60019.1 - 0.04 13.1 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease NaeI PQQ_2 PF13360.6 KUM60019.1 - 0.098 12.2 0.1 0.64 9.5 0.0 2.0 2 0 0 2 2 2 0 PQQ-like domain NAD_binding_9 PF13454.6 KUM60019.1 - 0.35 10.9 2.2 8.3 6.4 0.1 3.3 4 1 0 4 4 4 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.19 KUM60020.1 - 6.6e-49 166.9 0.1 9.5e-49 166.3 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM60020.1 - 2.2e-30 106.1 0.1 1.6e-29 103.3 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KUM60020.1 - 1.1e-05 24.8 0.0 2.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KUM60020.1 - 1.6e-05 24.4 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KUM60020.1 - 1.9e-05 24.4 0.1 0.0031 17.2 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM60020.1 - 2.2e-05 23.9 0.0 6.9e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM60020.1 - 4.1e-05 23.7 0.7 0.00026 21.1 0.3 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KUM60020.1 - 0.00013 21.3 0.0 0.0024 17.1 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KUM60020.1 - 0.0083 15.5 0.4 0.014 14.8 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KUM60020.1 - 0.019 13.7 0.1 0.037 12.7 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KUM60020.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase ThiF PF00899.21 KUM60020.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 ThiF family GIDA PF01134.22 KUM60020.1 - 0.17 10.9 0.0 0.41 9.7 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A GST_N PF02798.20 KUM60021.1 - 7e-14 51.9 0.0 1.1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KUM60021.1 - 1.8e-13 50.5 0.0 2.9e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KUM60021.1 - 8.9e-10 38.8 0.0 1.5e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KUM60021.1 - 1.5e-08 34.5 0.1 2.7e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KUM60021.1 - 2.4e-08 34.1 0.0 6e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KUM60021.1 - 4.4e-05 23.7 0.0 7.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KUM60021.1 - 0.055 14.2 0.0 0.1 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Polysacc_deac_1 PF01522.21 KUM60022.1 - 1.9e-18 66.6 0.0 2.8e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 KUM60022.1 - 0.0057 15.9 0.0 0.016 14.4 0.0 1.6 2 0 0 2 2 2 1 Divergent polysaccharide deacetylase GFRP PF06399.13 KUM60022.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) CBM-like PF14683.6 KUM60023.1 - 4.1e-29 101.6 0.1 1e-28 100.3 0.1 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KUM60023.1 - 1.1e-25 89.2 0.1 3.2e-25 87.7 0.1 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KUM60023.1 - 0.00019 21.6 0.0 0.00066 19.9 0.0 2.0 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 KUM60023.1 - 0.0031 17.6 0.1 0.082 13.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) Hydrophobin PF01185.18 KUM60024.1 - 1.2e-08 35.4 10.4 1.6e-08 35.1 10.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Nse5 PF08691.10 KUM60025.1 - 0.11 11.1 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 Fungal_trans PF04082.18 KUM60026.1 - 4.8e-24 84.8 0.3 6.4e-24 84.4 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60027.1 - 4.5e-09 36.3 7.1 7.1e-09 35.6 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM60027.1 - 2.2e-06 26.9 0.0 3.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 KUM60028.1 - 1.4e-104 350.0 0.0 1.7e-104 349.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM60028.1 - 4.6e-12 46.7 0.0 1e-11 45.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNB PF00773.19 KUM60029.1 - 6.9e-53 180.1 0.0 5.7e-50 170.5 0.0 2.2 1 1 0 1 1 1 1 RNB domain MARVEL PF01284.23 KUM60030.1 - 9.8e-05 22.4 0.7 0.00013 22.0 0.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain MFS_1 PF07690.16 KUM60031.1 - 6.9e-12 45.0 11.8 1.5e-11 43.8 11.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TipE PF16972.5 KUM60031.1 - 0.0061 15.8 0.9 0.011 15.0 0.9 1.3 1 0 0 1 1 1 1 Na+ channel auxiliary subunit TipE Fungal_trans_2 PF11951.8 KUM60032.1 - 1e-09 37.8 0.1 3.5e-09 35.9 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain EcKinase PF02958.20 KUM60033.1 - 2.2e-07 30.5 0.0 1.2e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 KUM60033.1 - 4e-07 30.2 0.2 1.5e-06 28.3 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KUM60033.1 - 0.022 14.4 0.0 0.058 13.0 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase Fungal_trans_2 PF11951.8 KUM60034.1 - 4.9e-10 38.8 2.2 5.3e-10 38.6 0.5 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60034.1 - 2.2e-05 24.5 9.4 3.8e-05 23.7 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-rbx1 PF12678.7 KUM60034.1 - 2.9 8.3 5.6 13 6.1 0.2 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain TRP PF06011.12 KUM60036.1 - 2.8e-40 138.4 22.2 7.8e-33 113.8 18.9 2.2 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KUM60036.1 - 0.00054 20.3 0.0 0.00084 19.7 0.0 1.3 1 0 0 1 1 1 1 ML-like domain DUF2873 PF11395.8 KUM60036.1 - 0.78 9.7 3.4 1.6 8.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) zf-RING_2 PF13639.6 KUM60037.1 - 3.5e-08 33.7 6.1 3.5e-08 33.7 6.1 2.7 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KUM60037.1 - 2.8e-05 23.8 6.3 2.8e-05 23.8 6.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KUM60037.1 - 3.3e-05 23.5 6.3 9.4e-05 22.1 6.3 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KUM60037.1 - 0.00092 19.5 7.6 0.00092 19.5 7.6 2.6 2 2 1 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KUM60037.1 - 0.0087 15.9 6.0 0.0087 15.9 6.0 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KUM60037.1 - 0.015 15.3 11.6 0.016 15.2 4.7 2.9 2 0 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.8 KUM60037.1 - 0.029 14.6 4.8 0.029 14.6 4.8 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KUM60037.1 - 0.059 13.4 5.4 0.2 11.7 2.7 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 KUM60037.1 - 0.51 10.5 6.4 1.6 8.9 6.4 1.9 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 KUM60037.1 - 0.84 10.0 10.5 0.079 13.3 5.2 2.0 2 1 0 2 2 2 0 RING-like domain Zn_clus PF00172.18 KUM60038.1 - 3.2e-05 24.0 13.1 5.1e-05 23.3 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM60038.1 - 0.0011 18.1 0.0 0.0024 17.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.23 KUM60039.1 - 9.9e-25 86.9 0.7 2e-24 85.9 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain MARVEL PF01284.23 KUM60040.1 - 0.14 12.2 13.2 0.23 11.5 13.2 1.3 1 1 0 1 1 1 0 Membrane-associating domain ThiS PF02597.20 KUM60041.1 - 4.2e-12 46.5 0.0 4.6e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 ThiS family Cys_Met_Meta_PP PF01053.20 KUM60042.1 - 3.4e-61 206.9 0.0 7.3e-61 205.8 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KUM60042.1 - 0.02 13.8 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.21 KUM60042.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II p450 PF00067.22 KUM60043.1 - 1.1e-55 189.3 0.0 1.5e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KUM60044.1 - 7.8e-50 169.5 0.0 1.1e-49 169.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KUM60044.1 - 7.7e-29 100.7 0.0 1.4e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KUM60044.1 - 2.8e-22 79.4 0.0 1.3e-21 77.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KUM60044.1 - 0.074 13.2 0.0 1 9.5 0.0 2.7 3 0 0 3 3 3 0 Ferric reductase NAD binding domain RTC PF01137.21 KUM60046.1 - 5.2e-48 163.1 0.0 7.2e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase ADH_N PF08240.12 KUM60049.1 - 1.4e-19 70.0 0.9 2.8e-19 69.0 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM60049.1 - 9.7e-19 67.6 0.2 1.8e-18 66.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Aldedh PF00171.22 KUM60050.1 - 6.6e-94 315.0 0.0 7.4e-94 314.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 KUM60052.1 - 4.2e-13 48.9 0.2 9.7e-13 47.7 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60052.1 - 1e-05 25.5 6.7 1e-05 25.5 6.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KUM60052.1 - 0.0025 18.2 8.4 0.012 16.0 1.2 3.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KUM60052.1 - 0.012 16.0 0.5 0.012 16.0 0.5 3.7 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KUM60052.1 - 0.031 15.1 1.1 0.031 15.1 1.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KUM60052.1 - 0.045 14.1 1.6 1.2 9.5 0.0 2.9 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KUM60052.1 - 0.71 10.2 4.8 2.1 8.7 4.8 1.9 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Carboxyl_trans PF01039.22 KUM60054.1 - 2e-77 260.9 0.0 2.5e-77 260.6 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CAP59_mtransfer PF11735.8 KUM60055.1 - 9.5e-75 251.4 0.0 1.2e-74 251.1 0.0 1.0 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 S-methyl_trans PF02574.16 KUM60056.1 - 1.1e-57 195.8 0.0 1.3e-57 195.6 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Macro PF01661.21 KUM60057.1 - 2.9e-31 108.0 0.0 4.3e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Macro domain Lar_restr_allev PF14354.6 KUM60057.1 - 0.014 15.7 0.2 0.037 14.4 0.2 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar HPP PF04982.13 KUM60058.1 - 3.6e-44 149.9 7.8 3.6e-44 149.9 7.8 1.4 2 0 0 2 2 2 1 HPP family DUF3792 PF12670.7 KUM60058.1 - 0.43 10.8 5.8 0.19 11.9 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) DUF4231 PF14015.6 KUM60058.1 - 3.7 8.1 5.3 4.6 7.8 0.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) AA_permease PF00324.21 KUM60060.1 - 6.1e-115 384.5 41.8 7.4e-115 384.3 41.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM60060.1 - 1.1e-38 133.3 48.9 1.4e-38 132.8 48.9 1.1 1 0 0 1 1 1 1 Amino acid permease ArAE_2_N PF10337.9 KUM60061.1 - 9.1e-127 423.9 0.1 6.7e-125 417.8 0.1 2.1 2 0 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KUM60061.1 - 5.5e-62 209.6 0.0 3.2e-61 207.1 0.0 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KUM60061.1 - 5.7e-10 39.4 15.6 5.7e-10 39.4 15.6 3.8 3 1 1 4 4 4 1 Fusaric acid resistance protein-like DUF2614 PF11023.8 KUM60061.1 - 4.6 7.4 5.7 0.79 9.8 0.4 2.3 2 0 0 2 2 2 0 Zinc-ribbon containing domain CPSase_L_D2 PF02786.17 KUM60062.1 - 1.9e-58 197.4 0.0 2.8e-58 196.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KUM60062.1 - 4.7e-31 107.1 0.0 1e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KUM60062.1 - 4.7e-28 97.9 0.0 9e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KUM60062.1 - 8.8e-11 41.5 0.2 2.1e-10 40.3 0.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KUM60062.1 - 1.6e-09 37.6 0.0 3.7e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KUM60062.1 - 3.4e-06 26.7 0.1 6.7e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KUM60062.1 - 9.9e-06 25.7 0.0 2.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 KUM60062.1 - 0.00076 19.4 0.0 0.0022 17.9 0.0 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain ATPgrasp_ST PF14397.6 KUM60062.1 - 0.0016 17.7 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp RimK PF08443.11 KUM60062.1 - 0.016 14.8 0.2 0.24 11.0 0.0 2.6 3 0 0 3 3 3 0 RimK-like ATP-grasp domain ATPgrasp_Ter PF15632.6 KUM60062.1 - 0.041 13.6 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.6 KUM60062.1 - 0.08 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like ATP-grasp_5 PF13549.6 KUM60062.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain MFS_1 PF07690.16 KUM60063.1 - 4.7e-16 58.7 39.5 5.1e-14 52.0 37.5 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Pam17 PF08566.10 KUM60063.1 - 0.72 9.7 2.8 1.7 8.5 0.4 2.5 1 1 0 2 2 2 0 Mitochondrial import protein Pam17 RTA1 PF04479.13 KUM60064.1 - 3.5e-72 242.4 7.3 4e-72 242.2 7.3 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF4231 PF14015.6 KUM60064.1 - 0.014 15.9 0.3 7.8 7.0 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Methyltransf_11 PF08241.12 KUM60066.1 - 0.0041 17.7 0.0 0.0097 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ATP-synt_DE PF00401.20 KUM60066.1 - 0.012 15.8 0.8 0.063 13.6 1.0 2.1 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain NDUFB11 PF17250.2 KUM60067.1 - 0.13 12.9 0.0 0.17 12.5 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase 11 kDa subunit MFS_1 PF07690.16 KUM60068.1 - 3.5e-48 164.3 33.7 3.5e-48 164.3 33.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM60068.1 - 5.2e-18 65.1 4.3 5.2e-18 65.1 4.3 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KUM60068.1 - 0.0021 16.4 2.4 0.0021 16.4 2.4 2.6 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 KUM60069.1 - 9e-72 242.3 0.0 1e-71 242.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Annexin PF00191.20 KUM60071.1 - 1.1e-62 207.9 0.6 2e-18 66.2 0.0 4.2 4 0 0 4 4 4 4 Annexin Retrotran_gag_3 PF14244.6 KUM60072.1 - 0.069 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KUM60072.1 - 0.26 11.0 0.5 0.42 10.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) SAP PF02037.27 KUM60075.1 - 3.2e-10 39.5 0.5 9e-10 38.1 0.0 2.0 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 KUM60075.1 - 1.8e-08 34.0 0.3 1.8e-08 34.0 0.3 1.8 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain Creatinase_N PF01321.18 KUM60075.1 - 0.024 15.3 0.7 1.4 9.6 0.1 2.3 2 0 0 2 2 2 0 Creatinase/Prolidase N-terminal domain DUF2868 PF11067.8 KUM60075.1 - 6.6 6.1 13.6 78 2.6 13.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2868) Usp PF00582.26 KUM60075.1 - 7.2 7.1 6.6 1 9.8 0.8 2.2 2 0 0 2 2 2 0 Universal stress protein family ABC2_membrane PF01061.24 KUM60076.1 - 3.7e-85 284.6 55.8 8.5e-51 172.3 24.3 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KUM60076.1 - 9.9e-40 136.2 0.0 2.1e-19 70.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KUM60076.1 - 3.1e-37 126.4 17.4 1.4e-34 117.8 0.1 4.1 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KUM60076.1 - 4.1e-16 59.4 0.6 1.5e-15 57.6 0.6 2.1 1 1 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KUM60076.1 - 4.2e-07 30.5 0.2 0.0032 17.9 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KUM60076.1 - 5.2e-06 26.5 0.6 0.0013 18.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KUM60076.1 - 7.6e-06 25.6 0.2 0.00047 19.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KUM60076.1 - 7.3e-05 23.0 0.0 0.0077 16.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KUM60076.1 - 0.00011 22.7 0.0 0.0098 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KUM60076.1 - 0.00012 21.3 18.8 0.00012 21.3 18.8 2.8 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 KUM60076.1 - 0.00018 21.2 1.7 0.017 14.9 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KUM60076.1 - 0.0038 17.1 4.3 1.3 8.8 0.3 3.8 5 0 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KUM60076.1 - 0.0054 16.2 0.0 0.28 10.6 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 KUM60076.1 - 0.0056 17.1 1.2 0.76 10.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KUM60076.1 - 0.0069 16.7 0.2 3.8 7.8 0.1 3.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KUM60076.1 - 0.01 15.6 0.3 1.6 8.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KUM60076.1 - 0.017 15.0 2.3 4.1 7.3 0.2 3.2 3 0 0 3 3 3 0 NACHT domain cobW PF02492.19 KUM60076.1 - 0.062 12.9 1.2 0.86 9.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KUM60076.1 - 0.08 13.0 0.1 24 5.0 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA PF00004.29 KUM60076.1 - 0.13 12.6 0.1 34 4.9 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zn_clus PF00172.18 KUM60077.1 - 1.1e-09 38.3 10.6 2.1e-09 37.3 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM60077.1 - 1.8e-06 27.1 0.2 2.3e-06 26.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CFEM PF05730.11 KUM60078.1 - 0.00052 20.1 6.2 0.00052 20.1 6.2 5.8 7 0 0 7 7 7 1 CFEM domain TP_methylase PF00590.20 KUM60078.1 - 0.17 11.8 8.5 3.3 7.6 1.1 2.5 2 0 0 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Tme5_EGF_like PF09064.10 KUM60078.1 - 0.51 10.3 3.2 3.8 7.5 3.2 2.6 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like CRF1 PF10380.9 KUM60080.1 - 0.024 15.0 0.1 0.024 15.0 0.1 2.8 3 0 0 3 3 3 0 Transcription factor CRF1 F-box-like PF12937.7 KUM60081.1 - 0.0005 19.9 0.1 0.00097 19.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like DUF2752 PF10825.8 KUM60082.1 - 0.47 10.6 3.6 0.79 9.8 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Dicty_REP PF05086.12 KUM60082.1 - 1.4 6.9 4.0 2.1 6.2 4.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BatA PF07584.11 KUM60082.1 - 1.5 9.2 5.1 6.3 7.2 0.4 2.6 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Abhydrolase_6 PF12697.7 KUM60083.1 - 6.3e-15 56.4 0.6 9.2e-15 55.8 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM60083.1 - 1.4e-10 40.8 0.0 2.7e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KUM60083.1 - 1.9e-05 24.5 0.1 2.8e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KUM60083.1 - 2.5e-05 24.2 0.2 4.5e-05 23.4 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KUM60083.1 - 0.0049 16.7 0.1 0.075 12.8 0.0 2.5 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KUM60083.1 - 0.0071 15.8 0.1 0.045 13.2 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 KUM60083.1 - 0.014 14.1 0.1 0.052 12.2 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Epimerase PF01370.21 KUM60085.1 - 8.1e-46 156.4 0.1 9.6e-46 156.2 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM60085.1 - 4.2e-21 75.7 0.0 5e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KUM60085.1 - 2.7e-17 62.7 0.0 3.7e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KUM60085.1 - 2e-15 56.7 0.0 5.4e-15 55.3 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KUM60085.1 - 6.2e-06 26.2 0.0 9.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KUM60085.1 - 7.2e-06 25.4 0.0 4.1e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KUM60085.1 - 1.6e-05 24.2 0.1 0.014 14.6 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein KR PF08659.10 KUM60085.1 - 0.079 12.9 0.0 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 KR domain ThiF PF00899.21 KUM60085.1 - 0.1 11.9 0.2 1.1 8.5 0.2 2.0 2 0 0 2 2 2 0 ThiF family Sacchrp_dh_NADP PF03435.18 KUM60085.1 - 0.12 12.6 0.1 0.53 10.5 0.1 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain AMP-binding PF00501.28 KUM60087.1 - 3.4e-155 516.8 0.8 4.2e-87 292.5 0.0 2.5 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KUM60087.1 - 2.9e-97 326.2 0.0 2.6e-39 135.2 0.0 3.4 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.25 KUM60087.1 - 4e-18 65.5 0.0 3.8e-10 40.0 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM60087.1 - 4.9e-12 46.7 0.1 9e-05 23.4 0.0 3.1 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain RuBisCO_large_N PF02788.16 KUM60087.1 - 0.17 12.0 0.1 0.46 10.7 0.1 1.7 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain ADH_zinc_N PF00107.26 KUM60089.1 - 1.5e-05 25.0 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM60089.1 - 0.00072 19.4 0.0 0.0018 18.1 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KUM60089.1 - 0.015 16.4 0.0 0.028 15.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NmrA PF05368.13 KUM60089.1 - 0.081 12.5 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family MFS_1 PF07690.16 KUM60090.1 - 9.2e-29 100.5 60.7 7.2e-28 97.5 53.0 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily DDDD PF10161.9 KUM60090.1 - 8.1 6.3 5.8 16 5.3 0.2 3.3 3 0 0 3 3 3 0 Putative mitochondrial precursor protein ABC_tran PF00005.27 KUM60091.1 - 5e-43 146.9 0.1 1.7e-21 77.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KUM60091.1 - 7.6e-26 91.4 21.7 2.3e-25 89.8 14.2 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KUM60091.1 - 9.9e-11 41.5 4.5 0.0038 16.7 0.5 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KUM60091.1 - 1.9e-09 37.8 1.2 0.037 13.9 0.1 4.2 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KUM60091.1 - 6.9e-06 25.3 0.4 0.018 14.1 0.4 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KUM60091.1 - 6.2e-05 23.0 0.1 0.034 14.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KUM60091.1 - 7.1e-05 22.5 3.0 0.25 11.1 0.8 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KUM60091.1 - 0.00014 22.1 4.0 0.02 15.1 0.4 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KUM60091.1 - 0.00021 21.8 0.2 0.027 14.9 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 KUM60091.1 - 0.0011 19.2 5.0 0.047 13.9 0.0 3.2 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KUM60091.1 - 0.0012 18.9 0.5 1.5 9.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_24 PF13479.6 KUM60091.1 - 0.0026 17.5 0.1 2.5 7.8 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KUM60091.1 - 0.0029 17.8 2.6 0.02 15.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KUM60091.1 - 0.0035 16.9 0.3 0.72 9.3 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 KUM60091.1 - 0.0051 17.3 2.3 0.74 10.3 0.2 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KUM60091.1 - 0.0057 16.4 0.2 4.2 7.1 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein TsaE PF02367.17 KUM60091.1 - 0.0065 16.5 0.6 0.053 13.5 0.1 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KUM60091.1 - 0.011 16.2 1.4 0.13 12.7 0.0 3.2 5 0 0 5 5 3 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 KUM60091.1 - 0.014 15.4 0.6 0.62 10.1 0.0 2.7 3 0 0 3 3 2 0 Dynamin family AAA_15 PF13175.6 KUM60091.1 - 0.016 14.9 0.3 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 KUM60091.1 - 0.019 15.5 3.0 1 9.9 0.1 3.0 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 KUM60091.1 - 0.024 14.2 4.5 0.04 13.5 1.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 KUM60091.1 - 0.026 13.8 0.4 6.3 6.0 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 KUM60091.1 - 0.052 13.5 2.5 0.11 12.5 0.4 2.3 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 KUM60091.1 - 0.052 13.9 0.2 0.36 11.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KUM60091.1 - 0.055 13.2 1.8 0.63 9.8 0.3 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 KUM60091.1 - 0.066 13.6 1.0 14 6.2 0.1 3.2 2 1 1 3 3 3 0 RNA helicase FtsK_SpoIIIE PF01580.18 KUM60091.1 - 0.075 12.4 2.5 8.1 5.7 0.5 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.6 KUM60091.1 - 0.081 12.5 3.3 9.6 5.7 0.0 3.1 4 0 0 4 4 3 0 AAA domain AAA_30 PF13604.6 KUM60091.1 - 0.088 12.5 1.7 0.33 10.6 0.3 2.3 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 KUM60091.1 - 0.11 12.0 0.6 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 KUM60091.1 - 0.12 12.3 0.3 0.74 9.7 0.1 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KUM60091.1 - 0.29 11.1 2.0 5.2 7.1 0.3 3.0 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 KUM60091.1 - 0.3 10.9 2.4 2.7 7.7 0.1 2.6 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 KUM60091.1 - 0.66 9.1 3.7 2 7.6 0.8 2.5 2 1 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 KUM60091.1 - 0.93 9.5 4.4 1.9 8.5 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain NTPase_1 PF03266.15 KUM60091.1 - 1.1 9.1 3.2 2.8 7.8 0.6 2.5 2 0 0 2 2 2 0 NTPase Roc PF08477.13 KUM60091.1 - 8.2 6.7 6.0 24 5.2 0.3 3.1 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Fungal_trans PF04082.18 KUM60092.1 - 6.3e-28 97.5 0.3 9.3e-28 97.0 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60092.1 - 4.6e-08 33.1 8.9 1.1e-07 31.8 8.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 KUM60093.1 - 1.9e-25 88.5 0.4 4.5e-14 52.0 0.1 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KUM60093.1 - 3.8e-05 23.7 0.0 0.025 14.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif DUF1676 PF07898.13 KUM60093.1 - 0.24 11.4 3.5 0.6 10.1 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) CCDC106 PF15794.5 KUM60093.1 - 5.4 6.7 16.8 1.1 8.9 5.4 2.7 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 106 Btz PF09405.10 KUM60094.1 - 5e-31 107.7 4.0 5e-31 107.7 4.0 2.0 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding I-set PF07679.16 KUM60095.1 - 1e-06 28.7 0.1 0.026 14.6 0.0 4.7 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KUM60095.1 - 0.0047 17.5 0.0 1.5 9.5 0.0 3.9 2 0 0 2 2 2 1 Immunoglobulin domain Peptidase_C12 PF01088.21 KUM60096.1 - 1.2e-61 208.1 0.0 1.9e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KUM60096.1 - 0.0015 18.4 0.2 0.0048 16.8 0.2 1.9 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases N_BRCA1_IG PF16158.5 KUM60097.1 - 1.7e-30 105.8 0.0 4.8e-30 104.3 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KUM60097.1 - 5.3e-22 77.4 53.1 3.1e-07 30.1 4.1 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 KUM60097.1 - 0.87 10.0 54.6 0.075 13.4 11.1 4.5 4 0 0 4 4 4 0 C1 domain Arylesterase PF01731.20 KUM60098.1 - 0.0049 17.0 0.1 0.024 14.8 0.0 2.4 2 1 0 2 2 2 1 Arylesterase Pkinase PF00069.25 KUM60099.1 - 1.6e-42 145.7 0.0 1.3e-38 132.9 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KUM60099.1 - 4.9e-09 35.9 0.0 0.00048 19.5 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KUM60099.1 - 0.0017 18.3 0.1 0.57 10.1 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KUM60099.1 - 0.0076 15.1 0.0 0.0094 14.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KUM60099.1 - 0.079 12.3 0.0 11 5.3 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 KUM60099.1 - 0.15 11.4 0.1 2.1 7.7 0.0 2.3 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family OTU PF02338.19 KUM60100.1 - 2.2e-07 31.4 0.0 3.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KUM60100.1 - 0.18 11.2 0.0 2.2 7.7 0.0 2.2 1 1 1 2 2 2 0 Peptidase C65 Otubain UN_NPL4 PF11543.8 KUM60100.1 - 0.23 12.0 0.0 0.49 10.9 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Oxysterol_BP PF01237.18 KUM60101.1 - 1.6e-53 181.9 0.0 2.5e-51 174.7 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Cnd1_N PF12922.7 KUM60102.1 - 4.4e-60 202.3 0.1 9.6e-60 201.2 0.1 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 KUM60102.1 - 5.4e-39 133.8 3.5 1e-33 116.7 0.8 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KUM60102.1 - 2.1e-11 44.1 1.2 5.5e-06 26.7 0.0 4.0 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 KUM60102.1 - 9.2e-09 34.8 10.0 0.058 13.7 0.0 6.5 5 1 2 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KUM60102.1 - 1.7e-05 25.2 11.9 0.18 12.3 0.1 6.1 6 1 0 6 6 6 2 HEAT-like repeat Adaptin_N PF01602.20 KUM60102.1 - 4.6e-05 22.2 11.5 0.02 13.4 0.8 4.1 4 2 0 4 4 4 2 Adaptin N terminal region RTP1_C1 PF10363.9 KUM60102.1 - 5.5e-05 23.3 0.2 0.044 14.0 0.0 3.6 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 KUM60102.1 - 7.9e-05 22.0 2.0 0.00039 19.7 0.7 2.6 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain FlbD PF06289.11 KUM60102.1 - 0.057 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins MFS_1 PF07690.16 KUM60103.1 - 3.3e-21 75.6 33.1 3.3e-21 75.6 33.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3149 PF11346.8 KUM60103.1 - 4.2 7.1 7.2 0.38 10.4 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) HTH_Tnp_Tc5 PF03221.16 KUM60104.1 - 0.0037 17.2 0.1 0.0072 16.3 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain BIR PF00653.21 KUM60104.1 - 0.074 13.7 5.7 7.1 7.4 0.1 3.4 2 1 0 2 2 2 0 Inhibitor of Apoptosis domain zf-C2H2_2 PF12756.7 KUM60104.1 - 2.2 8.7 6.7 1.1e+02 3.2 6.4 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) COesterase PF00135.28 KUM60105.1 - 8.1e-54 183.3 0.0 1e-53 183.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family FMO-like PF00743.19 KUM60106.1 - 2.7e-15 55.8 3.4 6.1e-14 51.3 0.5 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KUM60106.1 - 9.1e-11 41.8 0.0 1.8e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM60106.1 - 3.5e-09 36.3 0.0 2.5e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM60106.1 - 5.5e-09 35.6 0.2 4e-06 26.2 0.1 3.3 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KUM60106.1 - 1e-07 31.6 0.1 2.8e-06 26.8 0.0 2.6 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM60106.1 - 6.9e-05 22.9 0.1 0.0094 15.9 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KUM60106.1 - 0.00026 20.3 0.0 0.014 14.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KUM60106.1 - 0.00028 20.6 0.1 0.093 12.3 0.1 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 KUM60106.1 - 0.047 13.2 0.1 32 3.9 0.0 3.5 4 0 0 4 4 4 0 Glucose dehydrogenase C-terminus Ino80_Iec3 PF14612.6 KUM60107.1 - 2.9e-78 263.8 3.8 4.7e-78 263.1 3.8 1.3 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Nucleo_P87 PF07267.11 KUM60107.1 - 1 8.2 8.2 1.7 7.4 8.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FAD_binding_3 PF01494.19 KUM60108.1 - 1.3e-75 254.8 0.0 2.9e-75 253.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KUM60108.1 - 1.2e-27 97.0 0.0 2.3e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KUM60108.1 - 0.011 15.0 0.4 0.078 12.2 0.1 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KUM60108.1 - 0.029 13.4 0.0 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.14 KUM60108.1 - 0.048 12.4 0.0 0.24 10.1 0.0 2.0 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.12 KUM60108.1 - 0.19 10.7 0.1 0.31 10.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Bromodomain PF00439.25 KUM60109.1 - 1.4e-39 134.0 3.6 9.9e-20 70.4 0.3 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KUM60109.1 - 3.2e-18 65.8 2.2 4e-18 65.4 1.1 1.8 2 0 0 2 2 2 1 BAH domain HHH_6 PF14579.6 KUM60109.1 - 0.11 12.8 0.1 19 5.6 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif CDC45 PF02724.14 KUM60109.1 - 0.16 10.2 1.3 0.22 9.8 1.3 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KUM60109.1 - 1.8 7.8 4.7 3.2 7.0 4.7 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KUM60109.1 - 3.6 8.1 12.8 1.1 9.7 9.5 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 KUM60109.1 - 7.5 4.5 6.0 11 3.9 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Zn_clus PF00172.18 KUM60110.1 - 5.4e-07 29.6 6.4 5.4e-07 29.6 6.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_4 PF01063.19 KUM60111.1 - 8e-28 97.8 0.0 1e-27 97.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV ECR1_N PF14382.6 KUM60112.1 - 1.1e-15 57.1 0.4 2.2e-15 56.1 0.4 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KUM60112.1 - 0.0032 17.8 0.6 0.0061 16.9 0.6 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KUM60112.1 - 0.099 13.3 2.4 1.7 9.3 0.1 2.9 3 0 0 3 3 3 0 Exosome component EXOSC1/CSL4 IFRD PF05004.13 KUM60113.1 - 4.5e-90 301.8 1.9 6e-90 301.4 1.9 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Cnd3 PF12719.7 KUM60113.1 - 0.013 14.7 3.0 0.015 14.5 0.0 2.3 1 1 2 3 3 3 0 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KUM60113.1 - 0.019 15.3 0.0 2.1 8.8 0.0 3.0 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.22 KUM60113.1 - 0.027 14.7 1.8 11 6.6 0.0 4.4 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 KUM60113.1 - 0.11 13.1 0.1 27 5.4 0.0 3.4 3 0 0 3 3 3 0 HEAT-like repeat DUF789 PF05623.12 KUM60113.1 - 1.1 8.9 9.6 0.51 10.0 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF789) PDH PF02153.17 KUM60114.1 - 7.9e-13 48.0 0.0 1.1e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KUM60114.1 - 3.8e-06 27.4 0.0 8.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KUM60114.1 - 4.2e-06 27.0 0.0 1.1e-05 25.6 0.0 1.9 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KUM60114.1 - 0.00025 20.7 0.0 0.00069 19.3 0.0 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KUM60114.1 - 0.00079 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KUM60114.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 KUM60114.1 - 0.052 13.1 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KUM60114.1 - 0.076 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ERAP1_C PF11838.8 KUM60114.1 - 0.095 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Abhydrolase_3 PF07859.13 KUM60115.1 - 2.6e-41 141.8 0.0 3.3e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KUM60115.1 - 0.00022 20.9 0.0 0.00043 19.9 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KUM60115.1 - 0.00098 18.5 0.0 0.023 14.0 0.0 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 KUM60115.1 - 0.046 12.6 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase COesterase PF00135.28 KUM60115.1 - 0.1 11.4 0.0 0.28 10.0 0.0 1.7 1 1 0 1 1 1 0 Carboxylesterase family Fungal_trans PF04082.18 KUM60116.1 - 8.9e-10 38.0 1.5 1.3e-09 37.5 1.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60116.1 - 0.022 14.9 2.4 0.047 13.8 2.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 KUM60117.1 - 1.3e-19 70.7 0.0 3.1e-19 69.4 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KUM60117.1 - 9.3e-05 21.8 0.6 0.00035 19.9 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM60117.1 - 0.00017 20.9 2.8 0.12 11.6 0.5 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM60117.1 - 0.006 16.8 0.5 0.013 15.7 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM60117.1 - 0.019 14.6 1.8 0.03 13.9 0.6 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KUM60117.1 - 0.036 13.1 0.8 0.098 11.7 0.8 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KUM60117.1 - 0.036 13.2 2.5 0.056 12.5 2.5 1.3 1 0 0 1 1 1 0 FAD binding domain Ribosomal_S11 PF00411.19 KUM60119.1 - 3.9e-46 156.0 1.0 5e-46 155.6 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KUM60119.1 - 0.096 12.9 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) RICTOR_N PF14664.6 KUM60120.1 - 3.7e-126 421.1 0.5 3.7e-126 421.1 0.5 1.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 KUM60120.1 - 5.4e-38 129.7 0.0 1.6e-35 121.8 0.0 3.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 KUM60120.1 - 1.1e-36 124.8 1.4 1.8e-33 114.4 0.4 4.3 4 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 KUM60120.1 - 9.4e-26 89.9 0.9 8e-25 86.9 0.2 2.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KUM60120.1 - 3.1e-15 56.0 5.1 7.4e-15 54.8 5.1 1.6 1 0 0 1 1 1 1 Hr1 repeat HIF-1a_CTAD PF08778.10 KUM60120.1 - 0.15 11.7 0.0 8.7 6.1 0.0 2.6 2 0 0 2 2 2 0 HIF-1 alpha C terminal transactivation domain Uds1 PF15456.6 KUM60120.1 - 0.22 11.7 4.2 0.55 10.4 4.2 1.6 1 0 0 1 1 1 0 Up-regulated During Septation NAD_binding_4 PF07993.12 KUM60121.1 - 2e-35 122.2 0.0 4.8e-35 121.0 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KUM60121.1 - 1.5e-27 96.3 0.0 2.5e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KUM60121.1 - 1e-10 41.5 0.0 1.7e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KUM60121.1 - 0.0003 21.1 0.0 0.00085 19.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Aminotran_4 PF01063.19 KUM60122.1 - 9.9e-26 91.0 0.0 1.4e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV AAR2 PF05282.11 KUM60123.1 - 1.6e-97 327.1 0.0 1.9e-97 326.8 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein T4_deiodinase PF00837.17 KUM60124.1 - 0.032 13.5 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Iodothyronine deiodinase IgaA PF07095.11 KUM60124.1 - 0.19 9.7 0.0 0.28 9.1 0.0 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA MFS_1 PF07690.16 KUM60125.1 - 1.4e-33 116.3 41.8 2.1e-33 115.7 41.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KUM60128.1 - 1e-17 64.1 0.4 1.4e-17 63.7 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60128.1 - 6.9e-05 22.9 9.2 0.00013 22.0 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Paf67 PF10255.9 KUM60129.1 - 2.3e-159 530.8 0.0 2.8e-159 530.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KUM60129.1 - 0.085 13.0 0.0 0.6 10.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Adaptin_N PF01602.20 KUM60130.1 - 2.7e-116 389.2 6.8 3.3e-116 388.9 6.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KUM60130.1 - 1.4e-57 194.3 7.8 1.3e-55 187.9 0.6 3.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KUM60130.1 - 2.7e-12 46.9 4.1 0.00016 22.0 0.0 5.0 4 1 2 6 6 6 4 HEAT repeats HEAT PF02985.22 KUM60130.1 - 8.8e-11 41.1 3.4 0.0032 17.6 0.0 6.2 7 0 0 7 7 7 3 HEAT repeat Atx10homo_assoc PF09759.9 KUM60130.1 - 3e-06 27.2 0.2 0.77 9.8 0.0 4.0 3 1 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 KUM60130.1 - 0.00043 20.7 5.2 31 5.2 0.0 6.6 8 0 0 8 8 8 0 HEAT-like repeat CLASP_N PF12348.8 KUM60130.1 - 0.0043 16.7 0.4 1.7 8.1 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal Arm PF00514.23 KUM60130.1 - 0.042 13.9 2.0 3.4 7.9 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 KUM60130.1 - 0.33 10.7 2.7 17 5.2 0.0 3.2 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) DUF1077 PF06417.12 KUM60131.1 - 6.5e-50 168.1 3.1 8.5e-50 167.7 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Rubella_Capsid PF05750.11 KUM60131.1 - 2.3 7.7 9.1 3.5 7.1 9.1 1.3 1 0 0 1 1 1 0 Rubella capsid protein MFS_1 PF07690.16 KUM60132.1 - 1.6e-54 185.2 19.8 1.6e-54 185.2 19.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM60132.1 - 9.7e-13 47.8 18.9 9.3e-12 44.5 11.3 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_5 PF05631.14 KUM60132.1 - 0.0016 17.5 4.3 0.0016 17.5 4.3 1.6 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 KUM60132.1 - 0.0017 17.3 3.9 0.0017 17.3 3.9 2.0 2 0 0 2 2 2 1 MFS_1 like family OATP PF03137.20 KUM60132.1 - 0.0026 16.1 7.9 0.11 10.7 3.1 2.8 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Fe-S_biosyn PF01521.20 KUM60133.1 - 2.6e-09 37.2 0.0 7.5e-09 35.8 0.0 1.7 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Aminotran_5 PF00266.19 KUM60134.1 - 7.7e-11 41.6 0.0 2.9e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KUM60134.1 - 0.0054 15.3 0.0 0.011 14.3 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 KUM60134.1 - 0.011 14.4 0.2 0.022 13.5 0.2 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain YodL PF14191.6 KUM60134.1 - 0.067 14.0 0.0 6.7 7.6 0.0 2.5 2 0 0 2 2 2 0 YodL-like DegT_DnrJ_EryC1 PF01041.17 KUM60134.1 - 0.14 11.4 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans_2 PF11951.8 KUM60136.1 - 9.7e-09 34.5 2.8 8.7e-07 28.1 0.6 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain dUTPase PF00692.19 KUM60137.1 - 2.7e-10 40.0 0.0 4e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 dUTPase AMP-binding PF00501.28 KUM60138.1 - 1.7e-87 293.8 0.0 2.1e-87 293.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM60138.1 - 9.3e-12 45.8 0.0 3e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KUM60139.1 - 1.2e-55 188.9 28.5 2.9e-49 167.9 15.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KUM60139.1 - 8.6e-08 30.9 3.3 0.04 12.2 2.1 3.4 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KUM60139.1 - 2.3e-07 29.6 15.0 1.4e-06 27.1 7.9 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_1_like PF12832.7 KUM60139.1 - 0.0094 14.9 16.2 0.12 11.3 7.5 2.9 2 1 0 2 2 2 2 MFS_1 like family ATG22 PF11700.8 KUM60139.1 - 0.68 8.5 13.7 0.99 8.0 0.5 3.4 3 1 0 3 3 3 0 Vacuole effluxer Atg22 like PTR2 PF00854.21 KUM60139.1 - 0.91 8.3 11.4 0.32 9.8 0.8 2.4 2 0 0 2 2 2 0 POT family COesterase PF00135.28 KUM60140.1 - 1.6e-52 179.1 0.0 8.8e-51 173.3 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KUM60140.1 - 0.00079 19.3 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold HgmA PF04209.13 KUM60141.1 - 3.4e-167 556.5 0.2 4e-167 556.2 0.2 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase TPR_1 PF00515.28 KUM60143.1 - 5.5e-06 26.0 1.1 0.071 13.0 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KUM60143.1 - 1.1e-05 25.6 0.2 3.1e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KUM60143.1 - 3.1e-05 23.7 0.7 0.2 11.9 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KUM60143.1 - 0.0008 19.3 1.0 1.5 9.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KUM60143.1 - 0.019 15.6 2.6 0.37 11.5 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KUM60143.1 - 0.059 13.1 2.8 0.089 12.5 0.1 2.5 2 1 0 2 2 2 0 TPR repeat NRBF2_MIT PF17169.4 KUM60143.1 - 0.065 13.5 0.2 0.065 13.5 0.2 1.8 2 0 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 Gastrin PF00918.17 KUM60143.1 - 0.71 10.9 3.3 1 10.4 2.5 1.7 1 1 0 1 1 1 0 Gastrin/cholecystokinin family DUF2201_N PF13203.6 KUM60143.1 - 1.2 8.7 5.9 0.59 9.7 3.6 1.6 2 1 0 2 2 2 0 Putative metallopeptidase domain Rib_5-P_isom_A PF06026.14 KUM60144.1 - 5.1e-46 156.4 0.0 8.4e-46 155.7 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KUM60144.1 - 0.0022 18.0 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 2 DeoR C terminal sensor domain Tmemb_161AB PF10268.9 KUM60145.1 - 0.14 10.8 0.0 0.14 10.7 0.0 1.0 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB ATP_bind_1 PF03029.17 KUM60146.1 - 1.1e-78 264.4 0.0 1.4e-78 264.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 KUM60146.1 - 0.00079 19.4 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KUM60146.1 - 0.00085 18.4 0.1 0.0023 17.0 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KUM60146.1 - 0.003 17.6 0.0 0.028 14.5 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KUM60146.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KUM60146.1 - 0.031 14.6 0.0 0.073 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KUM60146.1 - 0.049 13.4 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_10 PF12846.7 KUM60146.1 - 0.067 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Fer4_NifH PF00142.18 KUM60146.1 - 0.095 12.1 0.4 0.45 9.9 0.0 2.2 2 1 1 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_18 PF13238.6 KUM60146.1 - 0.11 13.0 0.6 0.28 11.7 0.1 1.9 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KUM60146.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 KUM60146.1 - 0.22 11.9 2.5 0.3 11.5 0.2 2.2 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 KUM60147.1 - 1.4e-13 51.1 3.2 0.036 15.0 0.4 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM60147.1 - 0.094 13.0 0.1 19 5.6 0.0 3.5 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 KUM60147.1 - 0.11 12.1 0.0 0.3 10.7 0.0 1.7 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region DUF4979 PF16351.5 KUM60147.1 - 0.12 12.5 0.0 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4979) Citrate_synt PF00285.21 KUM60148.1 - 4e-21 75.5 0.0 1.9e-18 66.7 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 KUM60148.1 - 4.1e-19 69.1 0.0 1.8e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KUM60148.1 - 1.5e-14 54.1 0.1 2.7e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KUM60148.1 - 1e-05 25.3 0.0 0.00027 20.8 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain RNase_P_Rpp14 PF01900.19 KUM60149.1 - 1.2e-36 125.0 0.0 2e-36 124.3 0.0 1.4 2 0 0 2 2 2 1 Rpp14/Pop5 family MBOAT_2 PF13813.6 KUM60150.1 - 2.4e-22 79.0 2.3 6.9e-22 77.5 2.3 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family SBF_like PF13593.6 KUM60150.1 - 0.013 14.8 1.2 0.023 14.0 0.0 1.9 2 0 0 2 2 2 0 SBF-like CPA transporter family (DUF4137) Citrate_bind PF16114.5 KUM60151.1 - 9.9e-87 289.0 0.0 1.3e-86 288.6 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KUM60151.1 - 2e-08 34.0 0.0 3.1e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain SET PF00856.28 KUM60152.1 - 0.00046 20.6 0.1 0.0008 19.8 0.1 1.4 1 0 0 1 1 1 1 SET domain XAP5 PF04921.14 KUM60152.1 - 0.033 14.0 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator zf-RING_5 PF14634.6 KUM60153.1 - 3.7e-08 33.2 8.0 5.9e-08 32.5 8.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KUM60153.1 - 0.00013 21.7 4.8 0.00029 20.6 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KUM60153.1 - 0.00014 22.1 4.9 0.00025 21.3 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zinc_ribbon_9 PF14369.6 KUM60153.1 - 0.00052 20.2 0.7 0.0011 19.2 0.7 1.5 1 0 0 1 1 1 1 zinc-ribbon zf-C3HC4_3 PF13920.6 KUM60153.1 - 0.00057 19.7 6.7 0.001 18.8 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KUM60153.1 - 0.00076 19.3 5.6 0.0013 18.5 5.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KUM60153.1 - 0.0012 18.7 4.5 0.0032 17.3 4.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Allexi_40kDa PF05549.11 KUM60153.1 - 0.0021 17.7 2.4 0.0032 17.0 2.4 1.2 1 0 0 1 1 1 1 Allexivirus 40kDa protein Lebercilin PF15619.6 KUM60153.1 - 0.0034 17.1 8.9 0.0052 16.5 8.9 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease OmpH PF03938.14 KUM60153.1 - 0.0092 16.3 10.5 0.013 15.8 10.5 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 KUM60153.1 - 0.0098 15.5 0.9 0.012 15.2 0.9 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF5082 PF16888.5 KUM60153.1 - 0.011 16.0 6.8 0.011 16.0 6.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) zf-RING_UBOX PF13445.6 KUM60153.1 - 0.019 15.0 3.7 0.026 14.6 2.0 2.0 1 1 1 2 2 2 0 RING-type zinc-finger DUF4472 PF14739.6 KUM60153.1 - 0.045 14.5 7.5 0.078 13.7 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) zf-RING_6 PF14835.6 KUM60153.1 - 0.065 13.1 2.8 0.14 12.0 2.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Fmp27_WPPW PF10359.9 KUM60153.1 - 0.093 11.6 6.8 0.12 11.2 6.8 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Nudix_N_2 PF14803.6 KUM60153.1 - 0.12 12.3 0.8 0.35 10.8 0.8 1.8 1 0 0 1 1 1 0 Nudix N-terminal Spc24 PF08286.11 KUM60153.1 - 0.12 12.6 6.9 0.2 11.9 6.9 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 zf-UDP PF14569.6 KUM60153.1 - 0.23 11.6 1.3 9 6.5 0.7 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger DUF4349 PF14257.6 KUM60153.1 - 0.23 10.9 2.7 0.39 10.1 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Fib_alpha PF08702.10 KUM60153.1 - 0.24 11.6 9.2 0.4 10.9 9.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family zf-rbx1 PF12678.7 KUM60153.1 - 0.27 11.6 4.3 0.55 10.6 4.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain DZR PF12773.7 KUM60153.1 - 0.27 11.3 3.7 1 9.4 3.7 1.9 1 1 0 1 1 1 0 Double zinc ribbon SbcD_C PF12320.8 KUM60153.1 - 0.58 10.5 3.5 0.82 10.0 1.0 2.1 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain ZapB PF06005.12 KUM60153.1 - 0.64 10.5 7.5 1.2 9.7 7.1 1.6 1 1 0 1 1 1 0 Cell division protein ZapB zf-C3HC4_4 PF15227.6 KUM60153.1 - 0.67 10.2 5.7 1.4 9.1 5.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ABC_tran_CTD PF16326.5 KUM60153.1 - 0.69 10.2 4.4 2.1 8.7 4.2 1.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain Yippee-Mis18 PF03226.14 KUM60153.1 - 0.73 10.1 5.2 0.32 11.2 0.7 2.3 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Mod_r PF07200.13 KUM60153.1 - 0.9 9.6 12.8 2.7 8.1 12.6 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF4813 PF16072.5 KUM60153.1 - 2.2 7.9 9.0 3.1 7.4 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) FapA PF03961.13 KUM60153.1 - 3.6 6.1 6.8 4.9 5.7 6.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Zn_Tnp_IS91 PF14319.6 KUM60153.1 - 9.6 6.3 12.4 20 5.3 4.1 3.4 2 1 1 3 3 3 0 Transposase zinc-binding domain Cpn10 PF00166.21 KUM60154.1 - 7.4e-29 99.7 0.0 8.3e-29 99.5 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit XAP5 PF04921.14 KUM60156.1 - 7.4e-87 291.3 0.0 1.2e-86 290.6 0.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 KUM60156.1 - 0.0012 19.3 5.0 0.0012 19.3 5.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4604) Pol_alpha_B_N PF08418.10 KUM60156.1 - 0.068 13.1 6.0 0.12 12.4 6.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Fip1 PF05182.13 KUM60157.1 - 6.6e-20 70.3 1.3 1.2e-19 69.5 1.3 1.4 1 0 0 1 1 1 1 Fip1 motif Lactonase PF10282.9 KUM60158.1 - 0.0064 15.8 0.0 0.012 14.8 0.0 1.4 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller WD40 PF00400.32 KUM60158.1 - 0.012 16.5 9.6 26 5.9 3.2 5.7 5 1 0 5 5 5 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM60158.1 - 0.035 14.4 0.0 1.9 8.8 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain HAD_2 PF13419.6 KUM60159.1 - 1.2e-15 58.1 0.0 1.8e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KUM60159.1 - 5.3e-08 33.4 0.0 4.6e-06 27.1 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KUM60159.1 - 0.004 17.2 0.0 0.019 15.0 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like NIR_SIR PF01077.22 KUM60159.1 - 0.06 12.9 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain Stimulus_sens_1 PF13756.6 KUM60159.1 - 0.15 12.7 0.2 0.44 11.1 0.0 1.9 2 0 0 2 2 2 0 Stimulus-sensing domain TauD PF02668.16 KUM60160.1 - 1.2e-50 172.8 0.4 1.6e-50 172.4 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Nucleoporin_FG PF13634.6 KUM60161.1 - 1.5e-08 35.3 81.2 6.9e-05 23.6 44.5 3.3 1 1 1 2 2 2 2 Nucleoporin FG repeat region Baculo_PEP_C PF04513.12 KUM60161.1 - 0.0016 18.5 1.0 1.9 8.5 0.1 3.1 2 2 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KUM60161.1 - 0.0033 17.4 0.6 0.14 12.2 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) AMP-binding PF00501.28 KUM60162.1 - 9.1e-77 258.4 0.0 1.2e-76 258.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM60162.1 - 8.1e-15 55.6 0.3 1.9e-14 54.4 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NDUF_B12 PF08122.12 KUM60163.1 - 1.7e-28 98.4 1.3 2.5e-28 97.9 1.3 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family WD40 PF00400.32 KUM60164.1 - 1.7e-13 50.8 7.8 0.56 11.2 0.9 8.0 8 1 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM60164.1 - 5.3e-06 26.6 0.0 0.0093 16.2 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Cu_amine_oxid PF01179.20 KUM60165.1 - 3.1e-158 527.0 0.0 3.7e-158 526.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KUM60165.1 - 1.3e-23 83.2 1.7 4.8e-22 78.3 0.1 2.5 1 1 1 2 2 2 2 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KUM60165.1 - 3.3e-14 52.9 0.0 5.7e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CAF1 PF04857.20 KUM60166.1 - 1.5e-22 80.2 0.1 4.4e-11 42.5 0.0 2.5 3 0 0 3 3 3 2 CAF1 family ribonuclease adh_short_C2 PF13561.6 KUM60167.1 - 2.9e-39 135.0 0.5 9.5e-38 130.1 0.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM60167.1 - 3.3e-28 98.5 1.9 1.5e-27 96.4 1.9 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM60167.1 - 2.4e-07 30.8 0.2 4.7e-07 29.9 0.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM60167.1 - 0.065 12.7 0.0 4.8 6.6 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KUM60167.1 - 0.1 11.7 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4056 PF13265.6 KUM60167.1 - 0.22 10.9 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) CNH PF00780.22 KUM60168.1 - 3e-65 220.6 0.0 5.3e-65 219.8 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KUM60168.1 - 4.7e-35 121.5 0.7 8.7e-35 120.6 0.7 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KUM60168.1 - 1.6e-12 47.7 0.0 5.3e-12 46.0 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KUM60168.1 - 0.16 12.5 0.0 0.54 10.8 0.0 1.9 2 0 0 2 2 2 0 PH domain PAP2_C PF14360.6 KUM60169.1 - 0.034 14.7 0.0 5.4 7.6 0.0 2.2 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF4198 PF10670.9 KUM60170.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) RabGAP-TBC PF00566.18 KUM60171.1 - 9.5e-47 159.4 0.0 1.6e-46 158.7 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 KUM60171.1 - 8.5e-05 22.4 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 KUM60171.1 - 0.006 16.4 0.2 0.025 14.5 0.2 2.1 1 0 0 1 1 1 1 EF-hand domain Fungal_trans PF04082.18 KUM60173.1 - 3.6e-09 36.0 0.5 7.2e-09 35.1 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60173.1 - 7.1e-06 26.0 13.9 7.1e-06 26.0 13.9 2.4 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PgaD PF13994.6 KUM60173.1 - 0.073 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 PgaD-like protein MtN3_slv PF03083.16 KUM60173.1 - 0.14 12.2 1.0 15 5.7 0.1 2.7 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange 2OG-FeII_Oxy_2 PF13532.6 KUM60174.1 - 9.2e-32 110.8 0.0 1.6e-31 110.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SHOCT PF09851.9 KUM60174.1 - 0.0028 17.3 1.8 0.0063 16.2 1.8 1.6 1 0 0 1 1 1 1 Short C-terminal domain Fungal_trans PF04082.18 KUM60175.1 - 9.5e-14 51.1 0.5 1.6e-13 50.3 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1772 PF08592.11 KUM60176.1 - 2.9e-06 27.6 0.3 4e-06 27.2 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) TraX PF05857.11 KUM60176.1 - 0.098 12.7 0.2 0.29 11.2 0.1 1.7 1 1 1 2 2 2 0 TraX protein Sec2p PF06428.11 KUM60177.1 - 0.035 14.1 4.0 4.2 7.4 0.6 3.0 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p MRAP PF15183.6 KUM60177.1 - 0.15 12.0 1.0 0.3 11.0 1.0 1.4 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Velvet PF11754.8 KUM60178.1 - 6.9e-60 203.1 0.6 1.1e-59 202.4 0.0 1.5 2 0 0 2 2 2 1 Velvet factor Atrophin-1 PF03154.15 KUM60178.1 - 2.5e-05 22.9 3.2 2.5e-05 22.9 3.2 2.1 2 0 0 2 2 2 1 Atrophin-1 family Auts2 PF15336.6 KUM60178.1 - 0.0012 19.0 7.9 0.0032 17.6 7.9 1.7 1 0 0 1 1 1 1 Autism susceptibility gene 2 protein DUF3915 PF13054.6 KUM60178.1 - 0.66 10.0 12.9 1.2 9.1 12.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) PRP38_assoc PF12871.7 KUM60178.1 - 4.2 8.0 25.2 0.13 12.9 18.3 2.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Peptidase_M48 PF01435.18 KUM60180.1 - 1.9e-34 119.2 0.0 3.8e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Cpn60_TCP1 PF00118.24 KUM60181.1 - 3.2e-148 494.4 6.1 3.6e-148 494.2 6.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L12 PF00542.19 KUM60182.1 - 5.1e-20 71.6 3.9 3.8e-19 68.8 2.8 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KUM60182.1 - 5.2e-13 48.5 6.6 5.2e-13 48.5 6.6 3.4 4 1 0 4 4 4 1 Ribosomal protein L7/L12 dimerisation domain SpoVIF PF14069.6 KUM60182.1 - 0.061 13.1 0.4 0.28 11.0 0.0 2.1 2 1 0 2 2 2 0 Stage VI sporulation protein F TPR_19 PF14559.6 KUM60183.1 - 0.12 12.9 2.1 1.9 9.1 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KUM60183.1 - 0.18 12.5 3.7 2.9 8.7 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KUM60183.1 - 4.4 8.4 6.0 4.4 8.4 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat CPSF73-100_C PF11718.8 KUM60184.1 - 0.0068 16.0 0.7 0.012 15.1 0.7 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term E1_dh PF00676.20 KUM60185.1 - 2.1e-114 381.5 0.4 2.4e-114 381.3 0.4 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KUM60185.1 - 0.0012 18.2 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase PH_10 PF15411.6 KUM60187.1 - 7.7e-26 90.8 0.1 1.5e-25 89.9 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KUM60187.1 - 1.2e-13 51.7 0.0 2.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KUM60187.1 - 4.3e-12 46.2 0.0 3.7e-11 43.2 0.0 2.5 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 KUM60187.1 - 1.5e-06 28.8 0.0 3.6e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 KUM60187.1 - 0.00024 21.4 7.7 0.00044 20.5 7.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KUM60187.1 - 0.0068 16.3 7.2 0.012 15.6 7.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KUM60187.1 - 0.015 15.1 3.0 0.029 14.1 3.0 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 KUM60187.1 - 0.037 13.9 7.2 0.069 13.0 7.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KUM60187.1 - 0.039 13.6 8.5 0.021 14.5 5.4 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KUM60187.1 - 0.069 13.5 4.0 0.16 12.3 4.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain NlpE_C PF17185.4 KUM60187.1 - 0.17 12.2 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 NlpE C-terminal OB domain zf-C3HC4 PF00097.25 KUM60187.1 - 0.18 11.7 7.1 0.34 10.8 7.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KUM60187.1 - 1.5 9.2 6.8 2.8 8.3 6.8 1.4 1 0 0 1 1 1 0 RING-like domain Thiamine_BP PF01910.17 KUM60189.1 - 2.9e-30 104.0 0.2 3.4e-30 103.8 0.2 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Ins_P5_2-kin PF06090.12 KUM60190.1 - 6.3e-46 157.3 0.0 1.6e-45 156.0 0.0 1.6 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase S4 PF01479.25 KUM60191.1 - 6.2e-16 57.9 0.8 1.7e-15 56.4 0.0 2.1 2 0 0 2 2 2 1 S4 domain FUSC PF04632.12 KUM60191.1 - 2.8 6.4 6.7 2.1 6.8 5.0 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family SPG4 PF17325.2 KUM60191.1 - 5.5 8.1 6.1 1.3 10.1 0.5 2.3 2 0 0 2 2 2 0 Stationary phase protein 4 NAD_binding_10 PF13460.6 KUM60194.1 - 1.6e-06 28.2 0.0 2.1e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KUM60194.1 - 3.3e-05 23.5 0.0 8e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KUM60194.1 - 0.00041 19.5 0.0 0.0056 15.7 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KUM60194.1 - 0.013 14.9 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KUM60194.1 - 0.038 13.1 0.0 0.13 11.3 0.0 1.9 3 0 0 3 3 3 0 RmlD substrate binding domain KR PF08659.10 KUM60194.1 - 0.089 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 KR domain SYF2 PF08231.12 KUM60195.1 - 7.2e-56 189.0 14.2 7.2e-56 189.0 14.2 2.2 2 1 0 2 2 2 1 SYF2 splicing factor Adenylsucc_synt PF00709.21 KUM60195.1 - 0.054 12.4 0.7 0.12 11.2 0.1 1.7 1 1 1 2 2 2 0 Adenylosuccinate synthetase Ndc1_Nup PF09531.10 KUM60195.1 - 8.8 4.9 6.6 9.1 4.8 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IDO PF01231.18 KUM60196.1 - 4.4e-144 480.5 0.0 5.3e-144 480.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase YEATS PF03366.16 KUM60197.1 - 1.4e-34 117.9 1.8 2e-34 117.4 1.8 1.3 1 0 0 1 1 1 1 YEATS family Aminotran_5 PF00266.19 KUM60198.1 - 3.1e-09 36.3 0.0 3.3e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KUM60198.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family FLILHELTA PF10306.9 KUM60199.1 - 0.019 15.4 0.0 0.023 15.1 0.0 1.1 1 0 0 1 1 1 0 Hypothetical protein FLILHELTA COX7a PF02238.15 KUM60200.1 - 1.4e-18 67.0 7.8 4.3e-09 36.6 0.4 2.1 2 0 0 2 2 2 2 Cytochrome c oxidase subunit VII DUF1971 PF09313.11 KUM60200.1 - 0.097 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) Fungal_trans PF04082.18 KUM60201.1 - 1.8e-13 50.1 0.4 3.1e-12 46.1 0.5 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60201.1 - 5.6e-08 32.8 10.9 1e-07 31.9 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_RNApol_7kD PF03604.13 KUM60202.1 - 4.5e-17 61.4 5.7 5.8e-17 61.1 5.7 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 KUM60202.1 - 0.001 19.1 0.1 0.0011 19.0 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2197 PF09963.9 KUM60202.1 - 0.0015 18.8 0.8 0.14 12.4 0.0 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2197) zf_UBZ PF18439.1 KUM60202.1 - 0.0015 18.1 0.8 1.1 8.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KUM60202.1 - 0.013 15.5 0.3 0.019 15.0 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_13 PF09855.9 KUM60202.1 - 0.023 14.8 0.3 0.28 11.4 0.0 2.1 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zinc-ribbon_6 PF10005.9 KUM60202.1 - 0.032 14.9 0.2 0.042 14.5 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KUM60202.1 - 0.5 10.5 3.5 3.6 7.8 3.6 2.0 1 1 2 3 3 3 0 Zinc ribbon domain Glycos_transf_3 PF00591.21 KUM60203.1 - 1e-56 192.3 0.0 1.2e-54 185.6 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KUM60203.1 - 5.4e-09 35.8 0.2 1.3e-08 34.6 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DUF2263 PF10021.9 KUM60204.1 - 8e-22 78.2 0.0 2.2e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) DUF2219 PF09982.9 KUM60204.1 - 0.0099 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2219) Macro PF01661.21 KUM60204.1 - 0.041 13.9 0.0 0.092 12.8 0.0 1.6 1 0 0 1 1 1 0 Macro domain NRDE-2 PF08424.10 KUM60204.1 - 0.05 12.7 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Hamartin PF04388.12 KUM60204.1 - 0.053 12.2 10.9 0.071 11.8 10.9 1.1 1 0 0 1 1 1 0 Hamartin protein Fe_hyd_lg_C PF02906.14 KUM60205.1 - 5.2e-48 163.8 0.0 1e-47 162.9 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fapy_DNA_glyco PF01149.24 KUM60206.1 - 2.6e-35 121.5 0.0 4.9e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KUM60206.1 - 7.5e-22 77.1 0.0 1.6e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KUM60206.1 - 0.0025 16.7 0.0 0.006 15.4 0.0 1.7 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Abhydrolase_2 PF02230.16 KUM60207.1 - 5.1e-24 85.3 0.0 7.8e-16 58.5 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KUM60207.1 - 0.0019 17.7 0.2 0.0036 16.8 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 KUM60207.1 - 0.043 13.4 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KUM60207.1 - 0.061 12.6 0.1 0.23 10.7 0.0 2.0 2 1 1 3 3 3 0 Serine aminopeptidase, S33 NARP1 PF12569.8 KUM60208.1 - 6.6e-218 724.8 21.1 8.4e-216 717.8 14.4 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 KUM60208.1 - 6.4e-17 61.8 20.8 0.0065 17.0 0.9 7.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 KUM60208.1 - 2.3e-16 58.5 28.8 0.00043 20.2 0.2 10.6 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KUM60208.1 - 1.9e-15 56.2 22.6 0.026 15.3 0.2 11.5 8 3 4 12 12 12 5 Tetratricopeptide repeat TPR_16 PF13432.6 KUM60208.1 - 5.8e-12 46.1 22.8 0.0014 19.3 0.7 8.3 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KUM60208.1 - 1.4e-07 31.0 28.8 0.00011 21.8 0.2 9.4 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_11 PF13414.6 KUM60208.1 - 3.9e-07 29.6 14.4 0.00024 20.7 0.1 5.8 6 0 0 6 6 5 2 TPR repeat TPR_17 PF13431.6 KUM60208.1 - 1.8e-06 27.9 11.9 0.74 10.3 0.1 7.0 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KUM60208.1 - 2.8e-06 27.1 23.0 0.001 19.1 0.1 9.1 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 KUM60208.1 - 1e-05 25.5 11.7 0.0046 17.1 1.5 4.7 5 1 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM60208.1 - 4.7e-05 23.5 17.0 0.0081 16.4 0.6 5.8 4 3 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KUM60208.1 - 6.5e-05 23.1 22.7 0.31 11.3 0.3 6.7 6 1 1 7 7 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KUM60208.1 - 0.0031 17.6 4.2 11 6.1 0.0 5.1 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF3087 PF11286.8 KUM60208.1 - 0.032 13.7 3.2 0.15 11.5 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) TPR_3 PF07720.12 KUM60208.1 - 0.18 11.8 2.2 0.58 10.2 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat FXR_C3 PF16097.5 KUM60208.1 - 0.21 12.3 4.3 0.55 11.0 0.0 2.5 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 BTAD PF03704.17 KUM60208.1 - 0.27 11.7 7.5 0.084 13.3 1.1 3.3 2 1 1 3 3 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 KUM60208.1 - 0.27 11.9 19.1 9.4 7.1 0.2 7.1 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KUM60208.1 - 1.2 9.9 14.1 0.17 12.6 0.7 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.18 KUM60208.1 - 5.8 7.1 14.7 3 8.0 0.2 5.2 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain Cid2 PF09774.9 KUM60209.1 - 2.4e-55 187.4 0.8 2.8e-55 187.1 0.8 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Ribosomal_L10 PF00466.20 KUM60210.1 - 0.041 14.0 0.0 0.28 11.4 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L10 PI-PLC-X PF00388.19 KUM60211.1 - 1.2e-08 34.7 0.0 5e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain Pox_A3L PF05288.11 KUM60211.1 - 0.14 12.2 0.1 0.96 9.5 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A3L Protein TRI5 PF06330.11 KUM60213.1 - 3.8e-40 137.9 0.3 5.5e-40 137.3 0.0 1.3 2 0 0 2 2 2 1 Trichodiene synthase (TRI5) p450 PF00067.22 KUM60214.1 - 1.5e-55 188.8 0.0 1.8e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tim54 PF11711.8 KUM60215.1 - 1.6e-151 504.3 0.4 1.9e-151 504.1 0.4 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 2-oxoacid_dh PF00198.23 KUM60216.1 - 1.5e-77 260.2 0.1 2.2e-77 259.7 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KUM60216.1 - 1.1e-13 50.8 0.0 2.1e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KUM60216.1 - 6.2e-11 42.5 0.1 6.2e-11 42.5 0.1 2.1 2 0 0 2 2 2 1 e3 binding domain COesterase PF00135.28 KUM60217.1 - 5.9e-76 256.4 4.1 2.1e-75 254.5 4.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KUM60217.1 - 7.3e-06 25.6 0.1 1.5e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KUM60217.1 - 0.00099 19.0 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold YugN PF08868.10 KUM60217.1 - 0.13 12.2 0.2 1.3 8.9 0.1 2.2 2 0 0 2 2 2 0 YugN-like family Phytase PF02333.15 KUM60218.1 - 1.1e-69 235.3 2.0 2e-65 221.2 0.3 2.2 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.13 KUM60218.1 - 0.0012 19.1 9.5 0.0012 19.1 9.5 2.3 2 0 0 2 2 2 1 EGF-like domain Lactonase PF10282.9 KUM60218.1 - 0.017 14.4 0.1 5.9 6.0 0.0 3.0 3 1 0 3 3 3 0 Lactonase, 7-bladed beta-propeller UQ_con PF00179.26 KUM60220.1 - 5.5e-17 61.7 0.0 6.5e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KUM60220.1 - 0.043 14.1 0.0 0.045 14.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain Sec7_N PF12783.7 KUM60221.1 - 6.4e-42 143.1 5.7 2e-40 138.3 0.0 4.1 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KUM60221.1 - 3.9e-41 140.6 4.5 1.1e-40 139.2 4.5 1.9 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 KUM60221.1 - 2e-21 75.9 3.3 5.1e-21 74.5 2.5 1.9 2 0 0 2 2 2 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 KUM60221.1 - 0.006 16.4 0.0 0.94 9.4 0.0 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Ipi1_N PF12333.8 KUM60221.1 - 5.6 7.6 7.0 28 5.4 0.0 4.8 4 2 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Vps26 PF03643.15 KUM60222.1 - 8e-129 428.5 0.2 1e-128 428.2 0.2 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KUM60222.1 - 0.00035 20.7 0.1 0.72 9.9 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KUM60222.1 - 0.011 16.2 0.1 0.13 12.7 0.0 2.5 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain SKI PF01202.22 KUM60223.1 - 1.7e-10 41.2 0.0 3.4e-10 40.3 0.0 1.5 1 1 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 KUM60223.1 - 8.7e-08 32.4 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KUM60223.1 - 2.9e-07 31.1 0.0 1.5e-06 28.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 KUM60223.1 - 6.1e-05 23.0 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase Cytidylate_kin PF02224.18 KUM60223.1 - 0.0014 18.4 0.0 0.0035 17.1 0.0 1.6 2 0 0 2 2 2 1 Cytidylate kinase Rad17 PF03215.15 KUM60223.1 - 0.0022 17.9 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KUM60223.1 - 0.0038 17.5 0.0 0.0061 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KUM60223.1 - 0.0038 17.2 0.6 2.3 8.1 0.1 2.2 2 0 0 2 2 2 2 NTPase AAA_16 PF13191.6 KUM60223.1 - 0.0055 17.1 0.0 0.0084 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 KUM60223.1 - 0.0066 16.9 0.0 0.86 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KUM60223.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 KUM60223.1 - 0.016 15.6 0.0 0.037 14.4 0.0 1.7 2 0 0 2 2 1 0 RNA helicase ABC_tran PF00005.27 KUM60223.1 - 0.028 14.9 0.0 0.064 13.8 0.0 1.6 2 0 0 2 2 1 0 ABC transporter AAA PF00004.29 KUM60223.1 - 0.03 14.7 0.0 0.065 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KUM60223.1 - 0.034 13.4 0.0 0.064 12.5 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin Thymidylate_kin PF02223.17 KUM60223.1 - 0.034 13.8 0.0 0.44 10.2 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase ATPase_2 PF01637.18 KUM60223.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KUM60223.1 - 0.058 12.6 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KUM60223.1 - 0.059 13.1 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KUM60223.1 - 0.066 12.3 0.3 0.13 11.3 0.3 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KUM60223.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CoaE PF01121.20 KUM60223.1 - 0.074 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Dephospho-CoA kinase APS_kinase PF01583.20 KUM60223.1 - 0.16 11.9 0.0 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 Adenylylsulphate kinase p450 PF00067.22 KUM60225.1 - 8.5e-51 173.1 0.0 1e-50 172.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BAF250_C PF12031.8 KUM60227.1 - 0.021 14.2 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa Lipase_3 PF01764.25 KUM60229.1 - 8.6e-07 28.9 0.0 2.9e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 KUM60229.1 - 0.1 11.9 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KUM60229.1 - 0.21 11.4 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Catalase PF00199.19 KUM60230.1 - 7.1e-194 644.2 0.3 8.4e-194 644.0 0.3 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KUM60230.1 - 1.6e-10 41.0 0.0 4.1e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive SOXp PF12336.8 KUM60230.1 - 0.08 14.0 2.0 0.44 11.7 0.2 2.4 2 0 0 2 2 2 0 SOX transcription factor DUF3419 PF11899.8 KUM60231.1 - 4.1e-159 529.9 0.0 5.5e-159 529.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_31 PF13847.6 KUM60231.1 - 2.8e-07 30.4 0.0 8.5e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM60231.1 - 6.5e-07 30.0 0.0 1.2e-05 25.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM60231.1 - 1.3e-06 27.9 0.0 2.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KUM60231.1 - 1.7e-06 28.0 0.0 7e-05 22.7 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM60231.1 - 2.3e-06 28.2 0.0 1.1e-05 26.1 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM60231.1 - 2.5e-05 24.8 0.0 0.00032 21.3 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Ank_2 PF12796.7 KUM60233.1 - 7.6e-16 58.5 0.0 6.9e-10 39.4 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM60233.1 - 8.4e-10 39.0 0.1 1.7e-05 25.2 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM60233.1 - 1e-06 28.6 2.0 6.1 7.8 0.0 5.9 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 KUM60233.1 - 1.2e-06 28.7 0.1 0.19 12.1 0.0 4.1 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KUM60233.1 - 0.042 14.3 0.9 17 6.0 0.0 4.3 4 1 0 4 4 4 0 Ankyrin repeat Glyco_hydro_28 PF00295.17 KUM60234.1 - 3.4e-106 355.0 21.2 3.8e-106 354.8 21.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Allene_ox_cyc PF06351.11 KUM60234.1 - 0.0019 18.0 1.9 0.017 14.9 0.6 2.5 1 1 0 2 2 2 1 Allene oxide cyclase DUF5559 PF17714.1 KUM60234.1 - 0.086 12.7 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5559) FMN_bind PF04205.14 KUM60234.1 - 2.2 8.9 8.1 1.3e+02 3.3 8.1 3.1 1 1 0 1 1 1 0 FMN-binding domain Sugar_tr PF00083.24 KUM60235.1 - 2.2e-86 290.5 20.7 2.6e-86 290.3 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM60235.1 - 1.3e-16 60.5 26.9 5.6e-14 51.8 19.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KUM60235.1 - 0.0007 18.6 4.1 0.0007 18.6 4.1 2.3 2 1 0 2 2 2 1 MFS_1 like family Glyco_hydro_80 PF13647.6 KUM60235.1 - 0.063 12.8 0.0 6.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 80 of chitosanase A ECH_1 PF00378.20 KUM60236.1 - 1.2e-79 267.2 0.0 1.6e-79 266.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KUM60236.1 - 2e-36 126.1 0.3 5.3e-33 114.9 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Rer1 PF03248.13 KUM60237.1 - 3.7e-80 267.7 2.6 4.2e-80 267.5 2.6 1.0 1 0 0 1 1 1 1 Rer1 family DUF962 PF06127.11 KUM60237.1 - 0.23 11.6 3.8 2 8.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF962) Ctr PF04145.15 KUM60238.1 - 1.4e-23 84.2 0.1 1.8e-23 83.8 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Formyl_trans_N PF00551.19 KUM60239.1 - 2.1e-39 135.2 0.1 2.5e-39 134.9 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ECM11 PF15463.6 KUM60240.1 - 9.1e-42 142.8 0.0 5.8e-41 140.2 0.0 2.4 2 0 0 2 2 2 1 Extracellular mutant protein 11 VPS9 PF02204.18 KUM60241.1 - 8.2e-27 93.5 0.1 1.6e-26 92.5 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain zf-RING_2 PF13639.6 KUM60242.1 - 1e-13 51.3 4.6 1.6e-13 50.8 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KUM60242.1 - 3e-11 43.4 2.5 6e-11 42.5 2.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KUM60242.1 - 1.2e-09 37.8 3.7 2e-09 37.1 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM60242.1 - 7.7e-08 32.1 3.5 1.2e-07 31.5 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KUM60242.1 - 1.2e-07 31.3 2.4 2.3e-07 30.4 2.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KUM60242.1 - 3.8e-06 26.9 0.4 7.3e-06 25.9 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KUM60242.1 - 4.3e-06 26.3 2.4 7.3e-06 25.5 2.4 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KUM60242.1 - 2e-05 24.3 2.6 3.4e-05 23.6 2.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KUM60242.1 - 3.8e-05 23.5 2.7 5.8e-05 23.0 2.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KUM60242.1 - 0.00013 21.9 3.8 0.00026 20.9 3.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KUM60242.1 - 0.00035 20.4 1.6 0.00056 19.7 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KUM60242.1 - 0.0046 17.1 5.0 0.0071 16.4 5.0 1.3 1 0 0 1 1 1 1 RING-variant domain zf-Nse PF11789.8 KUM60242.1 - 0.0072 16.1 1.0 0.017 14.9 1.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 KUM60242.1 - 0.028 14.7 1.5 0.052 13.9 1.5 1.4 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 KUM60242.1 - 0.036 14.3 2.5 0.063 13.5 2.5 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 KUM60242.1 - 0.1 12.7 1.8 0.2 11.8 1.8 1.4 1 0 0 1 1 1 0 Zinc-finger zf-C3HC4_5 PF17121.5 KUM60242.1 - 0.13 12.1 0.9 0.27 11.2 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_9 PF13901.6 KUM60242.1 - 0.19 11.7 0.2 0.3 11.0 0.2 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING_6 PF14835.6 KUM60242.1 - 0.2 11.6 1.5 0.39 10.6 1.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KUM60242.1 - 0.22 11.3 3.3 0.37 10.6 3.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KUM60242.1 - 2.5 8.1 4.1 4.1 7.4 4.1 1.4 1 0 0 1 1 1 0 PHD-finger RNA_pol_I_TF PF04090.12 KUM60243.1 - 1.3e-10 41.1 0.0 1.4e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor TPR_6 PF13174.6 KUM60243.1 - 1 10.2 3.1 4 8.3 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat SNF2_N PF00176.23 KUM60244.1 - 1.1e-54 185.5 0.0 1.7e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KUM60244.1 - 7.8e-54 182.6 0.6 3.5e-53 180.4 0.6 2.0 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 KUM60244.1 - 6.1e-15 55.5 0.0 1.5e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM60244.1 - 9.5e-07 29.0 0.0 2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KUM60244.1 - 0.00097 18.4 0.0 0.0042 16.3 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 adh_short PF00106.25 KUM60245.1 - 2.4e-23 82.6 0.0 3.3e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM60245.1 - 3.2e-17 62.9 0.0 4.3e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM60245.1 - 1.5e-08 34.8 0.0 1.9e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KUM60245.1 - 2.9e-05 24.0 0.3 4.3e-05 23.5 0.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KUM60245.1 - 0.00087 18.8 0.0 0.0061 16.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM60245.1 - 0.0098 15.3 0.0 0.025 14.0 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase FMO-like PF00743.19 KUM60245.1 - 0.14 10.6 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Vac14_Fig4_bd PF11916.8 KUM60247.1 - 2.5e-80 268.3 8.0 2.5e-80 268.3 8.0 2.1 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KUM60247.1 - 2e-42 143.7 0.0 4.4e-40 136.2 0.0 3.9 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KUM60247.1 - 3.2e-09 37.1 2.0 0.026 15.0 0.0 5.3 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.22 KUM60247.1 - 3e-07 30.1 1.8 0.0011 19.1 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 KUM60247.1 - 7.2e-06 26.3 1.7 1 9.8 0.0 4.9 5 1 0 5 5 5 2 HEAT repeats Cnd1 PF12717.7 KUM60247.1 - 5.9e-05 23.2 1.1 0.085 12.9 0.4 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KUM60247.1 - 0.0059 16.6 0.0 16 5.7 0.0 4.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 KUM60247.1 - 0.038 13.9 0.3 11 5.8 0.0 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) RTP801_C PF07809.11 KUM60248.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 RTP801 C-terminal region WD40 PF00400.32 KUM60249.1 - 5.1e-40 134.7 21.3 1e-05 26.2 0.6 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KUM60249.1 - 8e-09 35.3 0.2 1.6e-08 34.3 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KUM60249.1 - 5e-08 32.6 0.2 2.1e-07 30.6 0.2 2.1 1 1 1 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 KUM60249.1 - 4.6e-06 26.8 1.2 2.4 8.5 0.1 4.6 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KUM60249.1 - 0.012 15.5 0.3 0.031 14.2 0.0 1.8 2 0 0 2 2 2 0 F-box Nup160 PF11715.8 KUM60249.1 - 0.36 9.4 9.1 5.9 5.4 0.2 4.8 3 1 2 6 6 6 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KUM60249.1 - 1.4 7.7 5.2 12 4.7 0.0 4.0 3 2 2 5 5 5 0 Partner and localizer of BRCA2 WD40 domain HORMA PF02301.18 KUM60250.1 - 2.3e-40 138.5 0.0 3.8e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 KUM60250.1 - 0.00017 21.4 8.8 0.00035 20.4 8.8 1.5 1 0 0 1 1 1 1 PHD-finger SIKE PF05769.11 KUM60250.1 - 0.08 12.9 0.3 0.14 12.0 0.3 1.3 1 0 0 1 1 1 0 SIKE family DUF3759 PF12585.8 KUM60252.1 - 7.9e-38 128.4 4.8 1e-37 128.0 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Ribosomal_L7Ae PF01248.26 KUM60253.1 - 2.6e-23 81.6 0.6 4.1e-23 80.9 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KUM60253.1 - 0.00042 20.4 0.0 0.00063 19.8 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 CLPTM1 PF05602.12 KUM60253.1 - 0.17 10.9 0.3 0.22 10.5 0.3 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Clat_adaptor_s PF01217.20 KUM60254.1 - 3.1e-42 143.9 0.0 6.4e-42 142.9 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain MMR_HSR1 PF01926.23 KUM60255.1 - 1.1e-18 67.3 0.0 1.7e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KUM60255.1 - 2.6e-06 27.6 0.0 0.00022 21.3 0.0 2.2 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KUM60255.1 - 0.00011 22.2 0.1 0.0044 17.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 KUM60255.1 - 0.00035 20.1 0.0 0.00046 19.8 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 KUM60255.1 - 0.0004 19.8 0.0 0.00057 19.3 0.0 1.1 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 KUM60255.1 - 0.00094 18.8 0.0 0.0066 16.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KUM60255.1 - 0.0021 17.5 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KUM60255.1 - 0.029 14.9 0.1 0.062 13.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KUM60255.1 - 0.038 13.7 0.0 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Roc PF08477.13 KUM60255.1 - 0.099 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase HEAT_2 PF13646.6 KUM60256.1 - 1.6e-07 31.6 2.5 1.3 9.5 0.1 5.3 4 1 1 5 5 5 2 HEAT repeats CLASP_N PF12348.8 KUM60256.1 - 8.7e-07 28.7 0.0 8.2e-05 22.3 0.0 2.8 3 0 0 3 3 3 1 CLASP N terminal HEAT PF02985.22 KUM60256.1 - 1.9e-05 24.5 0.2 5.6 7.5 0.0 5.7 5 0 0 5 5 5 1 HEAT repeat TAN PF11640.8 KUM60256.1 - 0.0012 19.0 0.1 0.0062 16.7 0.1 2.3 1 1 0 1 1 1 1 Telomere-length maintenance and DNA damage repair Cnd1 PF12717.7 KUM60256.1 - 0.0016 18.5 0.1 0.091 12.8 0.0 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 ADIP PF11559.8 KUM60256.1 - 0.017 15.2 12.5 0.046 13.8 12.5 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 KUM60256.1 - 0.021 14.4 3.9 0.014 15.0 2.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit COG5 PF10392.9 KUM60256.1 - 0.026 14.7 6.2 0.041 14.1 4.5 2.2 3 0 0 3 3 2 0 Golgi transport complex subunit 5 Proteasom_PSMB PF10508.9 KUM60256.1 - 0.045 12.3 1.3 0.32 9.4 0.0 2.6 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Golgin_A5 PF09787.9 KUM60256.1 - 0.15 11.5 10.8 0.3 10.5 10.8 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Syntaxin PF00804.25 KUM60256.1 - 0.18 11.4 6.9 0.62 9.7 6.8 2.0 2 0 0 2 2 2 0 Syntaxin PRP1_N PF06424.12 KUM60256.1 - 0.19 12.1 2.8 0.3 11.5 0.3 2.4 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal BicD PF09730.9 KUM60256.1 - 0.34 9.3 11.0 0.78 8.1 11.0 1.5 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D APG6_N PF17675.1 KUM60256.1 - 0.47 11.0 14.3 0.7 10.4 12.5 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 KUM60256.1 - 0.63 10.1 7.1 1.7 8.7 7.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 KUM60256.1 - 2.5 7.9 9.4 7.4 6.4 9.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Atg14 PF10186.9 KUM60256.1 - 2.9 6.9 7.7 5.9 5.9 7.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KUM60256.1 - 3.3 6.5 13.1 13 4.5 13.0 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 KUM60256.1 - 5.3 7.7 15.5 5.3 7.7 3.3 3.0 3 0 0 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GAS PF13851.6 KUM60256.1 - 5.7 6.2 14.8 3.7 6.9 12.0 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KUM60256.1 - 6.2 6.8 14.7 62 3.6 12.0 3.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 KUM60256.1 - 7.3 5.8 12.7 5.5 6.2 3.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Mito_carr PF00153.27 KUM60258.1 - 1.8e-46 156.0 1.0 3.2e-20 71.9 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Aconitase PF00330.20 KUM60259.1 - 2.3e-150 501.7 0.0 2.8e-150 501.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KUM60259.1 - 3e-43 147.3 0.0 5.9e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.8 KUM60260.1 - 6.5e-09 35.9 3.8 1e-08 35.2 3.8 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KUM60260.1 - 0.00052 20.3 2.2 0.00086 19.6 2.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 KUM60260.1 - 0.00078 19.2 0.7 0.0014 18.4 0.7 1.4 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_4 PF13894.6 KUM60260.1 - 0.00086 19.9 0.7 0.0019 18.9 0.7 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KUM60260.1 - 0.013 15.5 1.1 0.025 14.6 1.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KUM60260.1 - 0.025 14.9 0.4 0.042 14.2 0.4 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KUM60260.1 - 0.058 13.9 0.6 0.12 12.8 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Glyco_transf_20 PF00982.21 KUM60261.1 - 4.4e-201 668.6 0.0 5.1e-201 668.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 KUM60261.1 - 0.042 13.5 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain BLACT_WH PF17778.1 KUM60262.1 - 8.9e-18 64.0 0.0 1.3e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain WD40 PF00400.32 KUM60263.1 - 8.7e-52 172.0 22.3 4.7e-09 36.7 0.9 8.8 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM60263.1 - 6.3e-13 48.9 0.0 0.0069 16.7 0.1 4.8 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KUM60263.1 - 2.5e-08 33.0 1.0 0.014 14.1 0.1 4.2 5 1 1 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KUM60263.1 - 0.0022 16.8 0.1 0.49 9.1 0.0 3.8 2 1 1 3 3 3 1 Nup133 N terminal like Ribosomal_S17 PF00366.20 KUM60264.1 - 5.8e-14 52.0 0.5 1.2e-13 50.9 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 Ferlin_C PF16165.5 KUM60264.1 - 0.1 12.5 1.4 0.17 11.8 1.4 1.2 1 0 0 1 1 1 0 Ferlin C-terminus LSM PF01423.22 KUM60265.1 - 1.4e-17 63.1 0.0 2.6e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KUM60265.1 - 0.0043 17.2 0.0 0.0065 16.6 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Hat1_N PF10394.9 KUM60266.1 - 5.7e-52 176.2 0.0 1.2e-51 175.1 0.0 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus PPR_3 PF13812.6 KUM60268.1 - 2.9e-13 49.7 0.2 5.5e-05 23.2 0.0 5.1 4 2 3 7 7 7 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 KUM60268.1 - 8.3e-10 38.7 0.0 0.001 19.2 0.0 5.9 5 3 2 7 7 7 3 PPR repeat family PPR_long PF17177.4 KUM60268.1 - 2.1e-08 33.8 0.1 0.00062 19.2 0.1 2.7 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KUM60268.1 - 3.3e-05 23.8 8.3 5.6 7.4 0.1 7.0 8 0 0 8 8 8 2 PPR repeat DUF1415 PF07209.12 KUM60268.1 - 0.012 15.4 0.0 0.41 10.4 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1415) p450 PF00067.22 KUM60273.1 - 2.1e-67 227.9 0.0 2.5e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MSP1_C PF07462.11 KUM60274.1 - 0.18 10.5 0.8 0.22 10.2 0.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SARG PF15385.6 KUM60274.1 - 9.7 5.3 15.9 13 4.8 15.9 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein RNase_T PF00929.24 KUM60275.1 - 2.8e-07 31.2 0.0 5.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Exonuclease zf-C2H2_4 PF13894.6 KUM60275.1 - 0.00025 21.6 1.0 0.26 12.2 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KUM60275.1 - 0.00089 19.5 0.1 2 8.8 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KUM60275.1 - 0.0044 17.0 0.4 0.0096 15.9 0.4 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger DNA_pol_A_exo1 PF01612.20 KUM60275.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 3'-5' exonuclease zf-C2H2_2 PF12756.7 KUM60275.1 - 0.047 14.0 0.1 0.65 10.4 0.0 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KUM60275.1 - 0.38 11.2 2.0 8.8 6.9 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KUM60275.1 - 1.2 9.7 3.3 7 7.3 0.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Herpes_BTRF1 PF04682.12 KUM60275.1 - 8 5.7 9.8 0.89 8.8 2.8 2.4 1 1 1 2 2 2 0 Herpesvirus BTRF1 protein conserved region TPR_1 PF00515.28 KUM60278.1 - 2.1e-48 160.3 26.9 5e-08 32.4 0.1 10.8 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 KUM60278.1 - 2e-43 143.0 17.9 5.2e-06 26.2 0.0 10.4 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 KUM60278.1 - 1.6e-34 115.2 18.2 1.8e-06 27.7 0.0 10.0 9 1 0 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.6 KUM60278.1 - 4.6e-26 89.3 17.9 2.4e-05 24.4 0.1 9.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 KUM60278.1 - 4.1e-24 84.9 10.1 0.00039 20.9 0.0 6.7 3 3 3 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 KUM60278.1 - 3e-23 81.9 14.0 4.7e-05 23.6 0.1 7.3 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 KUM60278.1 - 3e-22 78.0 25.9 3.7e-05 23.3 1.5 9.3 6 3 3 9 9 9 6 TPR repeat TPR_16 PF13432.6 KUM60278.1 - 1.5e-20 73.5 14.3 4.6e-05 24.0 0.1 7.3 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 KUM60278.1 - 2e-19 68.6 13.1 0.00031 21.3 0.0 8.2 5 3 4 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.6 KUM60278.1 - 5.1e-18 64.4 12.4 0.0085 16.7 0.0 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 KUM60278.1 - 3.6e-17 61.1 10.7 0.028 14.4 0.0 8.9 9 1 0 9 9 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 KUM60278.1 - 4.2e-16 58.8 6.0 0.026 14.7 0.2 6.3 2 2 5 7 7 7 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM60278.1 - 1.4e-10 41.3 11.5 1.2e-07 31.9 1.4 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KUM60278.1 - 1.1e-07 31.4 4.6 0.00024 20.4 2.5 4.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_21 PF09976.9 KUM60278.1 - 5.1e-06 26.3 1.0 0.036 13.8 0.0 3.9 3 1 0 4 4 4 1 Tetratricopeptide repeat-like domain BTAD PF03704.17 KUM60278.1 - 1.1e-05 25.9 4.3 0.074 13.5 0.0 3.7 3 0 0 3 3 3 1 Bacterial transcriptional activator domain DUF2225 PF09986.9 KUM60278.1 - 0.0016 18.2 3.6 1.1 8.9 0.0 2.7 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_MalT PF17874.1 KUM60278.1 - 0.0031 16.9 2.3 0.031 13.6 0.0 2.5 2 1 1 3 3 3 1 MalT-like TPR region TPR_10 PF13374.6 KUM60278.1 - 0.0035 17.1 6.4 26 4.8 0.2 6.4 7 1 0 7 7 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 KUM60278.1 - 0.035 14.4 0.4 8.8 6.7 0.1 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat RPN6_N PF18055.1 KUM60278.1 - 0.17 12.2 1.5 0.8 10.1 0.3 2.5 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain ChAPs PF09295.10 KUM60278.1 - 0.35 9.8 2.0 6.1 5.7 0.2 2.7 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) FAT PF02259.23 KUM60278.1 - 0.59 9.3 5.9 1.5 7.9 3.2 2.4 1 1 1 2 2 2 0 FAT domain Exo70 PF03081.15 KUM60279.1 - 2.1e-81 273.9 0.0 7.7e-81 272.0 0.0 1.8 2 0 0 2 2 2 1 Exo70 exocyst complex subunit NPV_P10 PF05531.12 KUM60279.1 - 0.011 16.2 2.7 0.54 10.8 0.0 4.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Lyase_1 PF00206.20 KUM60280.1 - 4.6e-22 78.8 0.0 1.1e-21 77.5 0.0 1.6 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KUM60280.1 - 1.5e-16 60.7 0.2 1.1e-15 57.9 0.0 2.4 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus BCDHK_Adom3 PF10436.9 KUM60282.1 - 1.1e-74 249.7 0.0 1.5e-74 249.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KUM60282.1 - 6.5e-13 49.2 0.0 1.3e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KUM60282.1 - 0.089 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.17 KUM60282.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family SKN1 PF03935.15 KUM60284.1 - 1.6e-223 742.7 0.1 1.9e-223 742.4 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) NuiA PF07924.11 KUM60285.1 - 0.00099 19.5 0.1 0.99 9.8 0.0 2.2 2 0 0 2 2 2 2 Nuclease A inhibitor-like protein Ribosomal_L3 PF00297.22 KUM60286.1 - 3.7e-185 615.2 10.9 4.3e-185 615.0 10.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DSPc PF00782.20 KUM60287.1 - 3.7e-10 39.7 0.0 6.6e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KUM60287.1 - 2.9e-06 27.0 0.0 4.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KUM60287.1 - 0.024 14.6 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family EGF_alliinase PF04863.13 KUM60287.1 - 0.1 13.0 0.2 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 Alliinase EGF-like domain PTPlike_phytase PF14566.6 KUM60287.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.12 KUM60287.1 - 0.23 11.1 0.1 0.58 9.8 0.1 1.6 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PLA2_B PF01735.18 KUM60288.1 - 3.1e-27 95.2 0.0 1.2e-26 93.2 0.0 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain RIC3 PF15361.6 KUM60289.1 - 0.21 12.0 0.0 0.39 11.1 0.0 1.5 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Med18 PF09637.10 KUM60290.1 - 4.9e-63 213.3 0.0 5.5e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Med18 protein NAD_binding_4 PF07993.12 KUM60291.1 - 9.9e-39 133.0 0.0 1.8e-38 132.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KUM60291.1 - 2.7e-27 95.5 0.0 4.5e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KUM60291.1 - 1.1e-08 34.8 0.0 2.9e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KUM60291.1 - 2.4e-06 27.8 0.0 7.5e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Glyco_hydro_47 PF01532.20 KUM60293.1 - 3.8e-162 540.4 0.0 4.4e-162 540.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Peptidase_M20 PF01546.28 KUM60294.1 - 1.5e-16 60.7 0.2 2.5e-15 56.7 0.2 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KUM60294.1 - 6.2e-16 58.3 0.0 1.2e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KUM60294.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 AAA PF00004.29 KUM60295.1 - 2.1e-42 144.7 0.0 3.4e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KUM60295.1 - 1.6e-10 40.6 0.1 2.9e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KUM60295.1 - 1.9e-10 40.5 0.1 1.5e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KUM60295.1 - 2.6e-07 31.2 0.0 7.2e-05 23.2 0.1 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 KUM60295.1 - 4.3e-06 26.8 0.0 6.9e-05 22.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KUM60295.1 - 8.3e-06 26.0 0.0 2.8e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KUM60295.1 - 1.6e-05 24.7 0.0 3.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KUM60295.1 - 0.00051 19.3 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KUM60295.1 - 0.001 19.4 0.1 0.025 14.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 KUM60295.1 - 0.0023 17.2 0.2 0.0069 15.6 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_7 PF12775.7 KUM60295.1 - 0.0033 16.9 0.0 0.0067 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 KUM60295.1 - 0.0036 17.8 0.0 0.0099 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KUM60295.1 - 0.0081 15.6 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KUM60295.1 - 0.0081 16.5 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 KUM60295.1 - 0.0093 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TsaE PF02367.17 KUM60295.1 - 0.011 15.7 0.0 0.028 14.4 0.0 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KUM60295.1 - 0.011 15.4 0.0 0.03 14.0 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 KUM60295.1 - 0.017 15.0 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KUM60295.1 - 0.026 14.7 0.0 0.082 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KUM60295.1 - 0.027 14.5 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KUM60295.1 - 0.037 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KUM60295.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KUM60295.1 - 0.048 13.0 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 KaiC Prot_ATP_OB_N PF17758.1 KUM60295.1 - 0.057 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_25 PF13481.6 KUM60295.1 - 0.063 12.9 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain GAS PF13851.6 KUM60295.1 - 0.077 12.3 0.5 0.16 11.3 0.5 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PhoH PF02562.16 KUM60295.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 KUM60295.1 - 0.11 12.4 0.1 0.27 11.2 0.0 1.7 2 0 0 2 2 1 0 NACHT domain AAA_28 PF13521.6 KUM60295.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain CEP209_CC5 PF16574.5 KUM60295.1 - 0.16 12.1 1.1 0.47 10.6 1.1 1.7 1 1 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 Parvo_NS1 PF01057.17 KUM60295.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 KUM60295.1 - 0.19 11.5 0.0 0.46 10.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain eIF3_subunit PF08597.10 KUM60297.1 - 2.3e-70 237.3 26.6 2.5e-70 237.1 26.6 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF5384 PF17358.2 KUM60297.1 - 0.027 14.5 22.4 0.025 14.6 14.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5384) DUF4692 PF15763.5 KUM60297.1 - 0.61 10.5 6.5 0.15 12.5 2.1 2.2 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) DUF4746 PF15928.5 KUM60297.1 - 6.9 6.0 19.0 2.2 7.6 14.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Enolase_C PF00113.22 KUM60298.1 - 1.2e-152 507.3 0.0 1.5e-152 507.0 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KUM60298.1 - 3.6e-57 192.2 0.5 1e-56 190.7 0.1 1.8 2 0 0 2 2 2 1 Enolase, N-terminal domain MAAL_C PF07476.11 KUM60298.1 - 0.043 13.0 0.2 1.3 8.1 0.1 2.5 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus PNK3P PF08645.11 KUM60300.1 - 1.6e-52 177.5 0.0 2.7e-52 176.8 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KUM60300.1 - 8.6e-28 97.3 0.0 1.6e-13 51.0 0.1 3.1 2 1 1 3 3 3 2 AAA domain KTI12 PF08433.10 KUM60300.1 - 2.5e-05 23.9 1.3 0.079 12.4 0.0 2.4 2 1 1 3 3 3 2 Chromatin associated protein KTI12 Pkinase PF00069.25 KUM60301.1 - 7.3e-28 97.7 0.0 8.9e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM60301.1 - 1.7e-14 53.7 0.0 2.3e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KUM60301.1 - 4.4e-07 29.0 0.0 6.5e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RGS PF00615.19 KUM60302.1 - 7.8e-13 48.7 0.0 1.5e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain FAO_M PF16350.5 KUM60303.1 - 0.0044 17.3 0.4 0.029 14.7 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase central domain KOW PF00467.29 KUM60303.1 - 0.013 15.5 0.9 0.022 14.7 0.9 1.4 1 0 0 1 1 1 0 KOW motif Rtt106 PF08512.12 KUM60304.1 - 1.1e-29 102.7 0.1 5.4e-29 100.5 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KUM60304.1 - 1.1e-05 25.4 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Cwf_Cwc_15 PF04889.12 KUM60304.1 - 6.1 6.5 21.2 11 5.7 21.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein S36_mt PF10937.8 KUM60305.1 - 2e-40 138.9 0.3 2.4e-40 138.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial DUF647 PF04884.14 KUM60306.1 - 1.2e-12 48.0 1.4 2.3e-12 47.1 1.4 1.5 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF5342 PF17277.2 KUM60306.1 - 0.054 13.8 0.1 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5342) Pox_A32 PF04665.12 KUM60306.1 - 0.067 12.6 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein DUF647 PF04884.14 KUM60307.1 - 3.4e-75 252.8 0.1 4.4e-75 252.4 0.1 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Ras PF00071.22 KUM60309.1 - 5.3e-56 188.7 0.0 6.8e-56 188.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM60309.1 - 8e-22 77.7 0.0 1.2e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM60309.1 - 3.4e-07 29.9 0.0 5.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KUM60309.1 - 0.00086 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KUM60309.1 - 0.0022 17.6 0.0 0.0055 16.3 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 KUM60309.1 - 0.062 12.5 0.0 0.91 8.7 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 KUM60309.1 - 0.083 12.2 0.0 0.1 11.9 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region 14-3-3 PF00244.20 KUM60310.1 - 6.7e-107 356.0 0.2 8.2e-107 355.8 0.2 1.1 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 KUM60310.1 - 0.077 11.4 0.9 0.12 10.7 0.9 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Beach PF02138.18 KUM60312.1 - 5.5e-119 396.6 0.0 1e-118 395.7 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KUM60312.1 - 1.5e-12 47.5 0.0 3.3e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 KUM60312.1 - 6.8e-09 36.1 0.0 1.8e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 KUM60312.1 - 5.1e-06 27.1 4.3 0.011 16.6 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Aldo_ket_red PF00248.21 KUM60313.1 - 5.4e-62 209.6 0.0 7.4e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Sigma70_r1_2 PF00140.20 KUM60313.1 - 0.16 12.0 0.7 7.4 6.7 0.1 2.5 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 UQ_con PF00179.26 KUM60314.1 - 5.2e-36 123.4 0.2 2.5e-34 117.9 0.2 2.1 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme YL1 PF05764.13 KUM60314.1 - 4.7 7.3 10.2 5.9 6.9 10.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 KUM60314.1 - 5.4 6.3 12.0 6.7 6.0 12.0 1.1 1 0 0 1 1 1 0 SDA1 MmgE_PrpD PF03972.14 KUM60315.1 - 3.6e-120 401.5 0.6 4.1e-120 401.3 0.6 1.0 1 0 0 1 1 1 1 MmgE/PrpD family ABC_tran PF00005.27 KUM60317.1 - 1.3e-54 184.5 0.1 1.6e-31 109.6 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KUM60317.1 - 1.5e-52 179.0 18.8 2.4e-34 119.3 2.0 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KUM60317.1 - 1.8e-08 34.1 3.8 0.0046 16.4 0.2 4.1 4 1 1 5 5 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KUM60317.1 - 2.6e-07 31.3 0.4 0.00033 21.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KUM60317.1 - 3.4e-07 30.4 0.6 0.0054 16.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KUM60317.1 - 2.1e-05 24.5 0.2 0.055 13.4 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 KUM60317.1 - 2.2e-05 24.8 2.1 3.7 7.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KUM60317.1 - 5.3e-05 23.3 0.6 0.074 13.1 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 KUM60317.1 - 6.9e-05 23.1 1.4 0.045 13.9 0.2 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain IstB_IS21 PF01695.17 KUM60317.1 - 0.00021 21.1 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_16 PF13191.6 KUM60317.1 - 0.00036 21.0 0.8 1.7 9.0 0.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 KUM60317.1 - 0.00079 19.1 2.0 0.67 9.7 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SSE PF00437.20 KUM60317.1 - 0.0016 17.6 0.0 0.035 13.2 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 KUM60317.1 - 0.0023 17.5 0.3 0.89 9.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KUM60317.1 - 0.0043 16.6 0.2 2.3 7.7 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 KUM60317.1 - 0.013 14.8 1.1 4.2 6.6 0.1 2.8 3 0 0 3 3 3 0 Zeta toxin cobW PF02492.19 KUM60317.1 - 0.025 14.2 3.5 0.51 9.9 0.3 3.0 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KUM60317.1 - 0.032 14.7 0.9 3.7 8.0 0.1 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KUM60317.1 - 0.044 13.5 1.8 0.21 11.2 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_30 PF13604.6 KUM60317.1 - 0.045 13.5 1.5 3.9 7.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KUM60317.1 - 0.083 12.9 1.2 4.2 7.4 0.1 2.7 2 0 0 2 2 2 0 Dynamin family TrwB_AAD_bind PF10412.9 KUM60317.1 - 0.12 11.2 2.7 2.8 6.7 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TIP49 PF06068.13 KUM60317.1 - 0.13 11.4 0.6 9.9 5.3 0.2 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain PhoH PF02562.16 KUM60317.1 - 0.15 11.5 0.6 13 5.2 0.0 2.8 3 0 0 3 3 3 0 PhoH-like protein DEAD PF00270.29 KUM60317.1 - 0.15 11.8 0.3 19 5.0 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_33 PF13671.6 KUM60317.1 - 0.18 12.0 0.0 3.6 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 KUM60317.1 - 0.2 10.4 0.0 0.53 9.0 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein NACHT PF05729.12 KUM60317.1 - 0.29 11.0 2.6 2.9 7.8 0.2 2.6 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 KUM60317.1 - 0.31 11.2 4.0 13 6.0 0.1 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KUM60317.1 - 0.56 9.5 3.0 2.2 7.5 0.1 2.5 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_18 PF13238.6 KUM60317.1 - 1.1 9.8 4.2 19 5.8 0.2 3.3 3 1 0 3 3 2 0 AAA domain ADPRTs_Tse2 PF18648.1 KUM60318.1 - 0.033 14.2 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 Tse2 ADP-ribosyltransferase toxins AMP-binding PF00501.28 KUM60319.1 - 6.1e-146 486.3 0.0 1.9e-75 254.1 0.0 2.8 3 0 0 3 3 3 2 AMP-binding enzyme Condensation PF00668.20 KUM60319.1 - 7.2e-113 377.7 0.0 2.9e-37 128.4 0.0 5.6 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.25 KUM60319.1 - 8.2e-36 122.2 0.3 5.3e-12 45.9 0.0 5.5 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM60319.1 - 0.03 15.3 0.0 2.9 9.0 0.0 3.0 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain TAL_FSA PF00923.19 KUM60321.1 - 2.9e-93 312.4 0.2 3.3e-93 312.2 0.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Peptidase_S8 PF00082.22 KUM60322.1 - 4.5e-39 134.5 10.4 7.2e-39 133.8 10.4 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KUM60322.1 - 1.1e-20 74.1 0.4 1.9e-20 73.3 0.4 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 FA_hydroxylase PF04116.13 KUM60323.1 - 8.1e-22 78.0 12.5 8.1e-22 78.0 12.5 2.5 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily CRAL_TRIO PF00650.20 KUM60324.1 - 1.7e-24 86.4 0.0 2.3e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KUM60324.1 - 5.3e-11 42.5 0.4 1.6e-10 41.0 0.4 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SNase PF00565.17 KUM60325.1 - 1e-73 244.7 0.0 1.4e-23 83.4 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KUM60325.1 - 3.2e-23 82.1 0.0 1.9e-22 79.5 0.0 2.2 2 0 0 2 2 2 1 Tudor domain SMN PF06003.12 KUM60325.1 - 5.5e-05 22.5 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 KUM60325.1 - 0.052 14.0 0.0 0.35 11.4 0.0 2.5 3 0 0 3 3 3 0 Agenet domain Sod_Cu PF00080.20 KUM60326.1 - 3.2e-46 157.0 4.2 3.6e-46 156.9 4.2 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) RVT_2 PF07727.14 KUM60327.1 - 7.4e-12 45.4 0.0 9.4e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EMC1_C PF07774.13 KUM60330.1 - 4.1e-77 258.6 0.0 2.6e-76 256.0 0.0 2.1 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KUM60330.1 - 1e-30 107.1 19.6 3.9e-28 98.6 4.0 3.0 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.21 KUM60330.1 - 5.2e-07 29.3 0.7 0.033 14.1 0.1 4.8 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_3 PF13570.6 KUM60330.1 - 1.2 9.7 0.0 1.2 9.7 0.0 4.8 6 1 1 7 7 7 0 PQQ-like domain MFS_1 PF07690.16 KUM60332.1 - 1.4e-41 142.6 40.5 2.2e-41 141.9 34.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM60332.1 - 2.6e-09 36.5 9.2 2.6e-09 36.5 9.2 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KUM60332.1 - 0.12 10.6 4.5 0.17 10.2 2.4 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.8 KUM60333.1 - 7.7e-119 397.4 16.7 8.8e-119 397.2 16.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KUM60333.1 - 3.6e-07 29.4 2.5 3.6e-07 29.4 2.5 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily COX16 PF14138.6 KUM60333.1 - 0.037 14.5 0.0 8.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 DUF4381 PF14316.6 KUM60333.1 - 0.1 12.9 1.0 0.4 10.9 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4381) DUF3697 PF12478.8 KUM60334.1 - 0.0017 18.5 0.4 0.021 14.9 0.2 2.7 2 0 0 2 2 2 1 Ubiquitin-associated protein 2 Oxysterol_BP PF01237.18 KUM60335.1 - 8.2e-62 209.2 2.4 1.8e-59 201.5 2.4 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF3560 PF12083.8 KUM60335.1 - 0.036 14.2 0.2 0.075 13.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) SBD_N PF07005.11 KUM60336.1 - 4.4e-49 167.3 0.0 7.1e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Sugar-binding N-terminal domain NAD_binding_11 PF14833.6 KUM60336.1 - 4.5e-43 146.4 1.2 4.3e-25 88.3 0.0 2.8 3 0 0 3 3 3 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KUM60336.1 - 2.5e-32 112.3 1.5 3.7e-32 111.7 0.4 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NBD_C PF17042.5 KUM60336.1 - 1e-28 101.0 0.0 2.9e-28 99.5 0.0 1.8 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain 3HCDH_N PF02737.18 KUM60336.1 - 0.0013 18.6 0.3 0.0026 17.7 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KUM60336.1 - 0.012 16.1 0.8 0.068 13.8 0.1 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Gp_dh_C PF02800.20 KUM60336.1 - 0.02 14.5 0.1 0.044 13.4 0.1 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KUM60336.1 - 0.027 14.0 0.0 1.3 8.5 0.0 2.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PhageMin_Tail PF10145.9 KUM60336.1 - 0.094 12.6 1.5 0.34 10.7 1.5 1.9 1 0 0 1 1 1 0 Phage-related minor tail protein FMO-like PF00743.19 KUM60337.1 - 1.9e-13 49.7 0.0 8.9e-12 44.2 0.0 2.6 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KUM60337.1 - 2.4e-08 33.6 0.0 0.0017 17.6 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM60337.1 - 3.4e-07 30.4 0.0 8.4e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KUM60337.1 - 2.5e-06 26.9 0.0 0.01 15.0 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KUM60337.1 - 1.4e-05 24.5 0.0 0.0011 18.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM60337.1 - 0.015 15.3 0.5 0.53 10.3 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 KUM60337.1 - 0.14 11.7 0.0 9.9 5.6 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.17 KUM60337.1 - 0.19 11.0 0.0 5.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Thi4 family zf-H2C2_2 PF13465.6 KUM60338.1 - 6.6e-06 26.3 5.5 0.0063 16.9 1.4 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KUM60338.1 - 3.8e-05 23.9 1.5 3.8e-05 23.9 1.5 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KUM60338.1 - 7.4e-05 22.6 6.6 0.002 18.1 0.5 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KUM60338.1 - 0.00014 22.4 12.5 0.00026 21.6 1.2 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger C1_1 PF00130.22 KUM60338.1 - 0.0065 16.3 5.1 0.01 15.7 5.1 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 KUM60338.1 - 0.0067 16.0 5.4 0.96 9.1 1.2 2.4 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 KUM60338.1 - 0.025 14.2 1.2 0.048 13.3 1.2 1.4 1 1 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 KUM60338.1 - 0.88 10.1 5.9 4.5 7.8 1.3 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Glyco_hydro_3 PF00933.21 KUM60340.1 - 2.7e-68 230.7 0.0 3.6e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 KUM60340.1 - 3.4e-17 62.7 0.0 8.4e-09 35.7 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KUM60340.1 - 2.9e-14 53.2 0.1 1.8e-07 31.5 0.0 2.9 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KUM60340.1 - 9.1e-13 48.3 0.0 8e-09 35.5 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.22 KUM60340.1 - 3.4e-05 23.9 0.0 8.6e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_9 PF13527.7 KUM60340.1 - 5.6e-05 23.2 0.0 0.16 12.1 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KUM60340.1 - 0.00017 21.8 0.0 0.18 11.9 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KUM60340.1 - 0.0033 17.3 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 KUM60340.1 - 0.031 14.4 0.1 15 5.8 0.0 2.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 KUM60340.1 - 0.16 12.0 0.0 31 4.7 0.0 2.7 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase DHDPS PF00701.22 KUM60342.1 - 3.3e-08 32.6 0.0 4e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.16 KUM60343.1 - 2.7e-34 118.6 25.9 2.7e-34 118.6 25.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Hydantoinase_B PF02538.14 KUM60344.1 - 2.2e-209 696.2 0.1 2.5e-209 696.0 0.1 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KUM60345.1 - 5.8e-100 334.3 0.1 1.7e-99 332.8 0.0 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KUM60345.1 - 1.6e-57 194.1 0.2 4.1e-55 186.2 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region NAD_binding_2 PF03446.15 KUM60346.1 - 2.2e-24 86.4 0.0 3.6e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KUM60346.1 - 6.8e-10 39.2 0.0 1.2e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DHDPS PF00701.22 KUM60347.1 - 1.5e-24 86.2 0.0 1.9e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PGM_PMM_I PF02878.16 KUM60348.1 - 1.4e-31 109.1 0.1 2.1e-31 108.5 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KUM60348.1 - 1.4e-26 92.9 0.0 2.4e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KUM60348.1 - 1e-16 61.4 0.1 2.5e-16 60.1 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KUM60348.1 - 1.6e-07 31.4 0.0 3.9e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GFO_IDH_MocA PF01408.22 KUM60349.1 - 4.1e-11 43.8 0.0 1.2e-10 42.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KUM60349.1 - 0.00014 21.9 0.0 0.0003 20.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sugar_tr PF00083.24 KUM60350.1 - 1.4e-79 268.1 22.2 1.8e-79 267.7 22.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM60350.1 - 7.3e-26 90.9 30.9 7.3e-26 90.9 30.9 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM60350.1 - 0.00066 18.2 4.3 0.0012 17.4 4.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KUM60350.1 - 0.0027 16.6 5.7 0.0027 16.6 5.7 2.3 2 1 0 2 2 2 1 MFS_1 like family TMEM40 PF15817.5 KUM60350.1 - 0.12 12.1 0.1 5 6.9 0.0 2.9 2 0 0 2 2 2 0 Transmembrane protein 40 family K_oxygenase PF13434.6 KUM60351.1 - 3.1e-16 59.5 0.0 6.6e-11 41.9 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KUM60351.1 - 3.9e-06 26.3 1.0 0.013 14.7 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM60351.1 - 1.6e-05 24.3 0.0 0.2 10.8 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM60351.1 - 1.6e-05 24.7 0.3 0.54 9.8 0.0 3.7 3 1 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KUM60351.1 - 3.1e-05 24.0 0.1 0.25 11.3 0.1 3.2 3 1 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.17 KUM60351.1 - 0.00058 19.2 0.1 0.0035 16.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KUM60351.1 - 0.0024 17.0 0.2 0.18 10.8 0.1 2.4 2 1 1 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KUM60351.1 - 0.0025 16.9 0.0 0.0058 15.7 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Shikimate_DH PF01488.20 KUM60351.1 - 0.0025 17.9 0.0 0.83 9.7 0.1 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KUM60351.1 - 0.0029 16.4 0.0 0.097 11.4 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KUM60351.1 - 0.011 14.9 0.0 0.14 11.2 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 KUM60351.1 - 0.013 15.7 1.0 0.16 12.2 0.0 3.0 4 0 0 4 4 3 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KUM60351.1 - 0.028 13.7 1.3 0.058 12.6 0.0 2.1 3 0 0 3 3 3 0 FAD binding domain TrkA_N PF02254.18 KUM60351.1 - 0.19 12.0 0.0 0.62 10.3 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain SR-25 PF10500.9 KUM60351.1 - 2.1 7.9 13.6 0.42 10.2 7.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FIT1_2 PF17357.2 KUM60351.1 - 4 7.6 12.1 0.87 9.7 0.1 3.2 3 0 0 3 3 3 0 Facilitor Of iron transport 1 and 2 GST_N PF02798.20 KUM60352.1 - 5.2e-16 58.7 0.0 8.9e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KUM60352.1 - 2.5e-13 50.2 0.0 4.6e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KUM60352.1 - 7.7e-11 42.1 0.0 1.5e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KUM60352.1 - 0.083 13.6 0.0 0.81 10.5 0.0 2.4 2 1 0 2 2 2 0 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KUM60352.1 - 0.096 13.0 0.0 0.23 11.8 0.0 1.6 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein Sugar_tr PF00083.24 KUM60353.1 - 3.4e-91 306.4 22.2 4.3e-91 306.0 22.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM60353.1 - 1.2e-16 60.6 61.4 5.2e-13 48.6 28.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF148 PF02520.17 KUM60353.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF4293 PF14126.6 KUM60353.1 - 4.4 7.5 6.2 11 6.2 2.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) RNase_T PF00929.24 KUM60354.1 - 4.9e-27 95.5 0.0 5.6e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Cwf_Cwc_15 PF04889.12 KUM60355.1 - 0.031 14.0 13.3 0.46 10.2 3.5 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CHCH PF06747.13 KUM60357.1 - 0.023 14.9 2.7 0.044 13.9 2.7 1.6 1 0 0 1 1 1 0 CHCH domain MTCP1 PF08991.10 KUM60357.1 - 0.038 14.2 2.3 0.079 13.2 2.3 1.7 1 1 0 1 1 1 0 Mature-T-Cell Proliferation I type NatB_MDM20 PF09797.9 KUM60358.1 - 2.1e-92 310.0 0.1 4.2e-92 309.0 0.1 1.5 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 KUM60358.1 - 0.00054 20.4 1.6 0.067 13.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Lactamase_B PF00753.27 KUM60359.1 - 1.7e-09 38.0 0.9 5.8e-09 36.2 0.9 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KUM60359.1 - 9.8e-05 22.0 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KUM60359.1 - 0.015 15.2 0.0 0.017 15.0 0.0 1.1 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Sulfotransfer_3 PF13469.6 KUM60359.1 - 0.041 14.3 0.0 0.043 14.2 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase family Lactamase_B PF00753.27 KUM60360.1 - 0.00042 20.4 0.0 0.00061 19.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_hydro_28 PF00295.17 KUM60361.1 - 3.4e-28 98.6 6.1 4.5e-28 98.3 6.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 KUM60361.1 - 2.3e-09 37.4 10.9 5.2e-09 36.3 3.9 3.2 1 1 2 3 3 3 1 Pectate lyase superfamily protein Ank_2 PF12796.7 KUM60362.1 - 1.3e-36 125.0 1.3 3.1e-07 30.9 0.1 6.6 4 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM60362.1 - 6.3e-31 106.4 7.3 8.2e-05 23.1 0.0 9.4 6 2 3 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM60362.1 - 1.3e-22 79.6 8.0 0.0078 16.5 0.0 8.6 7 3 2 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM60362.1 - 1.3e-20 71.2 8.0 8.5e-05 22.7 0.0 11.6 12 1 0 12 12 12 4 Ankyrin repeat Ank PF00023.30 KUM60362.1 - 2.1e-17 62.7 14.7 0.00016 21.9 0.0 11.2 12 1 0 12 12 12 2 Ankyrin repeat PNP_UDP_1 PF01048.20 KUM60362.1 - 1.3e-08 34.4 0.5 6.6e-08 32.1 0.5 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.6 KUM60362.1 - 0.0045 17.3 0.1 0.027 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KUM60362.1 - 0.0065 16.9 0.1 0.12 12.7 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KUM60362.1 - 0.018 15.0 0.1 0.069 13.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Peptidase_S41 PF03572.18 KUM60363.1 - 3.2e-06 26.8 0.0 5.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 MFS_1 PF07690.16 KUM60364.1 - 7.8e-30 104.0 40.9 7.8e-30 104.0 40.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily G-patch_2 PF12656.7 KUM60364.1 - 1.2e-24 86.2 0.8 6.3e-24 83.8 0.1 2.5 2 0 0 2 2 2 1 G-patch domain G-patch PF01585.23 KUM60364.1 - 0.015 15.2 0.3 0.048 13.6 0.2 2.0 2 0 0 2 2 2 0 G-patch domain WD40 PF00400.32 KUM60365.1 - 7.7e-57 188.0 14.7 4.2e-07 30.6 0.0 13.7 12 2 0 12 12 12 9 WD domain, G-beta repeat Utp13 PF08625.11 KUM60365.1 - 1.6e-49 167.5 0.1 2.5e-49 166.9 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KUM60365.1 - 3.1e-12 46.6 0.5 0.14 12.5 0.0 7.8 6 2 3 9 9 9 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KUM60365.1 - 0.00036 19.6 0.3 0.23 10.4 0.0 4.4 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KUM60365.1 - 0.0014 17.5 0.9 3.2 6.4 0.1 4.6 5 2 0 5 5 5 1 Nup133 N terminal like Nup160 PF11715.8 KUM60365.1 - 0.048 12.3 11.0 8.1 5.0 2.0 5.3 3 3 3 6 6 6 0 Nucleoporin Nup120/160 Frtz PF11768.8 KUM60365.1 - 0.054 11.8 0.0 0.36 9.1 0.0 2.1 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF1699 PF08004.11 KUM60365.1 - 0.18 11.5 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) Dmrt1 PF12374.8 KUM60366.1 - 0.025 15.0 0.2 0.1 13.1 0.2 2.1 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 FAD_binding_4 PF01565.23 KUM60367.1 - 1.7e-22 79.7 0.0 2.7e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KUM60367.1 - 9.6e-13 48.3 0.0 1.3e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain TPR_12 PF13424.6 KUM60368.1 - 1.3e-120 393.8 35.8 1.1e-20 73.7 0.7 7.9 2 1 7 9 9 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 KUM60368.1 - 1.3e-102 333.2 13.0 4.7e-14 51.7 0.1 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_1 PF00515.28 KUM60368.1 - 3.3e-26 90.0 18.3 0.00052 19.7 0.1 9.3 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.6 KUM60368.1 - 2.3e-23 80.4 13.3 0.012 15.6 0.0 9.6 11 0 0 11 11 9 7 Tetratricopeptide repeat Patatin PF01734.22 KUM60368.1 - 2.8e-21 76.7 0.0 6.2e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_16 PF13432.6 KUM60368.1 - 7.8e-18 64.9 1.6 0.19 12.4 0.4 9.0 8 2 1 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 KUM60368.1 - 1.8e-15 55.8 5.5 0.25 11.7 0.0 8.7 8 0 0 8 8 8 2 Tetratricopeptide repeat DUF1925 PF09094.11 KUM60368.1 - 4.6e-11 42.9 0.0 7.2 7.0 0.0 7.8 8 0 0 8 8 8 1 Domain of unknown function (DUF1925) TPR_4 PF07721.14 KUM60368.1 - 1.7e-10 40.5 0.0 9.9 7.1 0.0 7.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KUM60368.1 - 1.9e-10 40.7 6.9 1.2 10.2 0.1 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KUM60368.1 - 7.4e-10 38.7 1.2 0.0004 19.9 0.2 2.5 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 KUM60368.1 - 1.8e-08 33.8 16.0 7.6 6.9 0.1 9.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_17 PF13431.6 KUM60368.1 - 3.6e-08 33.3 0.1 31 5.2 0.0 8.2 8 0 0 8 8 8 0 Tetratricopeptide repeat NB-ARC PF00931.22 KUM60368.1 - 3.6e-07 29.6 0.0 7.2e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain NRBF2_MIT PF17169.4 KUM60368.1 - 4.6e-06 26.8 2.3 48 4.3 0.0 7.9 9 0 0 9 9 9 0 MIT domain of nuclear receptor-binding factor 2 NACHT PF05729.12 KUM60368.1 - 8.8e-06 25.7 0.0 2.4e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KUM60368.1 - 1.4e-05 25.5 0.4 5.2e-05 23.7 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KUM60368.1 - 4.7e-05 23.7 0.0 0.00017 21.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KUM60368.1 - 0.036 13.8 0.1 0.11 12.2 0.1 1.8 1 1 1 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 KUM60368.1 - 0.093 12.3 0.1 1.8 8.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain TPR_19 PF14559.6 KUM60368.1 - 0.1 13.1 12.6 0.76 10.3 0.4 5.5 2 1 5 8 8 8 0 Tetratricopeptide repeat Stimulus_sens_1 PF13756.6 KUM60368.1 - 0.13 12.8 0.6 2.6 8.7 0.0 3.0 2 1 0 2 2 2 0 Stimulus-sensing domain AAA_18 PF13238.6 KUM60368.1 - 0.14 12.7 0.0 0.52 10.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain UCH PF00443.29 KUM60372.1 - 1e-20 74.4 0.0 4.2e-20 72.3 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KUM60372.1 - 7.6e-12 45.4 0.4 1.6e-11 44.4 0.1 1.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Proteasome PF00227.26 KUM60375.1 - 1.6e-26 93.0 0.0 1.8e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit zf-C3HC4 PF00097.25 KUM60376.1 - 6.2e-09 35.6 4.8 6.2e-09 35.6 4.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KUM60376.1 - 7.1e-08 32.7 7.0 7.1e-08 32.7 7.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KUM60376.1 - 1.2e-07 31.7 7.7 1.2e-07 31.7 7.7 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KUM60376.1 - 1.8e-07 30.9 3.9 1.8e-07 30.9 3.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KUM60376.1 - 2.1e-07 30.7 6.0 2.1e-07 30.7 6.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KUM60376.1 - 3.9e-06 26.8 6.1 3.9e-06 26.8 6.1 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KUM60376.1 - 4.6e-06 26.5 6.0 4.6e-06 26.5 6.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KUM60376.1 - 0.0024 17.9 1.0 0.0024 17.9 1.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KUM60376.1 - 0.0028 17.5 9.2 0.0043 16.9 4.9 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 HUN PF08729.10 KUM60376.1 - 0.006 16.5 3.3 0.006 16.5 3.3 2.8 2 1 0 2 2 2 1 HPC2 and ubinuclein domain zf-rbx1 PF12678.7 KUM60376.1 - 0.0072 16.6 5.9 0.0072 16.6 5.9 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KUM60376.1 - 0.014 15.3 3.7 0.014 15.3 3.7 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DZR PF12773.7 KUM60376.1 - 0.25 11.4 11.9 2.4 8.3 0.2 3.0 2 1 0 2 2 2 0 Double zinc ribbon IBR PF01485.21 KUM60376.1 - 0.35 11.1 7.4 24 5.2 0.1 2.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain TRAP_alpha PF03896.16 KUM60376.1 - 6.7 5.8 8.6 5.5 6.1 1.2 2.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit zf-RING_4 PF14570.6 KUM60376.1 - 8.7 6.2 13.4 0.045 13.6 2.4 2.7 2 1 1 3 3 2 0 RING/Ubox like zinc-binding domain WD40 PF00400.32 KUM60377.1 - 4e-19 68.6 11.1 2.2e-05 25.1 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM60377.1 - 0.02 15.2 0.0 0.059 13.7 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Astro_capsid_p PF12226.8 KUM60377.1 - 0.86 8.7 4.3 1.3 8.1 4.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein XFP_N PF09364.10 KUM60378.1 - 1.2e-135 452.0 0.0 1.8e-135 451.4 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 KUM60378.1 - 5.9e-78 261.0 0.0 8.7e-78 260.4 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 KUM60378.1 - 3e-75 251.8 0.0 4.8e-75 251.1 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 KUM60378.1 - 0.014 15.2 0.1 0.034 13.9 0.1 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Acetate_kinase PF00871.17 KUM60379.1 - 3.6e-93 312.4 0.0 4.3e-93 312.1 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family RTA1 PF04479.13 KUM60381.1 - 1.5e-72 243.5 12.1 2e-72 243.2 12.1 1.1 1 0 0 1 1 1 1 RTA1 like protein CLU PF13236.6 KUM60382.1 - 5.1e-74 248.8 0.0 9.1e-74 248.0 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KUM60382.1 - 4.9e-53 179.8 0.0 1e-52 178.7 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KUM60382.1 - 6.8e-26 90.4 6.7 1.2e-12 47.9 0.2 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 KUM60382.1 - 1.6e-25 89.3 0.1 4.8e-25 87.7 0.1 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 KUM60382.1 - 1.8e-22 78.5 0.9 1.3e-06 28.1 0.0 5.2 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KUM60382.1 - 0.00012 22.0 7.1 0.37 11.0 0.2 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KUM60382.1 - 0.00055 19.9 4.9 0.068 13.4 0.7 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF727 PF05303.12 KUM60382.1 - 0.079 13.0 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF727) EnY2 PF10163.9 KUM60382.1 - 0.3 11.5 1.5 3.5 8.1 0.2 3.2 3 0 0 3 3 3 0 Transcription factor e(y)2 TPR_17 PF13431.6 KUM60382.1 - 0.45 11.0 2.8 1.9e+02 2.8 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_16 PF13191.6 KUM60383.1 - 4.2e-06 27.3 0.0 1.2e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KUM60383.1 - 0.0014 18.6 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KUM60383.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Meiosis_expr PF15163.6 KUM60383.1 - 0.068 13.8 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Meiosis-expressed AAA_5 PF07728.14 KUM60383.1 - 0.073 13.1 0.1 0.42 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) T4SS PF07996.11 KUM60383.1 - 0.1 13.0 0.1 0.27 11.6 0.1 1.7 2 0 0 2 2 2 0 Type IV secretion system proteins AAA PF00004.29 KUM60383.1 - 0.11 12.9 0.0 0.48 10.9 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NAD_binding_6 PF08030.12 KUM60384.1 - 4.7e-19 69.0 0.0 9.4e-17 61.6 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KUM60384.1 - 1.3e-18 67.3 10.0 1.3e-18 67.3 10.0 2.7 3 1 1 4 4 4 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KUM60384.1 - 2.1e-14 53.5 0.0 8.6e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain DUF4405 PF14358.6 KUM60384.1 - 8.3 7.0 15.8 12 6.6 1.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) WD40 PF00400.32 KUM60385.1 - 9.6e-28 95.9 12.6 6e-05 23.7 0.7 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.7 KUM60385.1 - 1.7e-09 37.4 0.1 3.8e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KUM60385.1 - 0.0001 22.5 0.2 1.8 9.0 0.0 4.8 2 1 4 6 6 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KUM60385.1 - 0.00051 19.8 0.0 0.002 18.0 0.0 1.9 2 0 0 2 2 2 1 F-box domain PQQ PF01011.21 KUM60385.1 - 0.0025 17.7 0.2 4.8 7.3 0.0 3.5 3 0 0 3 3 3 1 PQQ enzyme repeat WD40_like PF17005.5 KUM60385.1 - 0.0095 15.3 0.3 0.063 12.6 0.1 2.2 3 0 0 3 3 3 1 WD40-like domain PQQ_2 PF13360.6 KUM60385.1 - 0.0096 15.5 0.0 0.21 11.1 0.0 2.4 1 1 1 2 2 2 2 PQQ-like domain DUF5046 PF16465.5 KUM60385.1 - 0.013 14.9 0.2 0.3 10.5 0.0 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF5046) Nup160 PF11715.8 KUM60385.1 - 0.024 13.3 0.3 4.4 5.8 0.0 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 F-box_4 PF15966.5 KUM60385.1 - 0.03 14.2 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 F-box DUF3642 PF12182.8 KUM60385.1 - 0.053 13.8 0.1 0.31 11.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial lipoprotein EcsC PF12787.7 KUM60386.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 EcsC protein family EB1 PF03271.17 KUM60387.1 - 1.1e-16 60.7 1.1 2.3e-16 59.8 1.1 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KUM60387.1 - 2.9e-06 27.4 0.6 5e-06 26.7 0.6 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 KUM60387.1 - 0.0038 15.8 0.0 0.0059 15.2 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus UL6 like CH_2 PF06294.11 KUM60387.1 - 0.073 13.2 0.3 0.13 12.4 0.3 1.5 1 0 0 1 1 1 0 CH-like domain in sperm protein Adeno_E3_CR2 PF02439.15 KUM60388.1 - 0.0017 18.1 0.2 0.0028 17.4 0.2 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Glycophorin_A PF01102.18 KUM60388.1 - 0.018 15.3 0.4 0.018 15.3 0.4 3.3 1 1 2 3 3 3 0 Glycophorin A SKG6 PF08693.10 KUM60388.1 - 0.046 13.1 0.3 0.16 11.4 0.3 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Cation_ATPase_N PF00690.26 KUM60389.1 - 7e-10 38.4 0.2 3.4e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Cation transporter/ATPase, N-terminus Ferlin_C PF16165.5 KUM60389.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Ferlin C-terminus Cation_ATPase_C PF00689.21 KUM60390.1 - 6.5e-47 159.6 9.2 6.5e-47 159.6 9.2 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KUM60390.1 - 2.9e-35 121.4 0.2 2.9e-35 121.4 0.2 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KUM60390.1 - 6.2e-20 71.1 0.0 1.4e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KUM60390.1 - 3.7e-19 69.9 0.6 1.5e-18 67.9 0.6 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KUM60390.1 - 2e-05 24.5 0.1 0.002 17.9 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.8 KUM60390.1 - 0.16 12.1 0.1 0.16 12.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) HAD PF12710.7 KUM60390.1 - 0.17 12.3 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase P16-Arc PF04699.14 KUM60391.1 - 1.3e-45 155.5 0.0 1.5e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) PAS_4 PF08448.10 KUM60391.1 - 0.089 13.1 0.1 0.19 12.0 0.0 1.6 2 0 0 2 2 2 0 PAS fold Methyltransf_11 PF08241.12 KUM60392.1 - 8.7e-09 35.9 0.0 2.1e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM60392.1 - 1.5e-07 31.4 0.0 2.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM60392.1 - 3.5e-06 27.6 0.0 1.1e-05 26.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM60392.1 - 1e-05 26.2 0.0 2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM60392.1 - 0.00046 20.0 0.0 0.0045 16.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Dynactin_p62 PF05502.13 KUM60393.1 - 6.1e-193 641.9 0.0 6.1e-193 641.9 0.0 1.6 2 0 0 2 2 2 1 Dynactin p62 family Mu-like_Com PF10122.9 KUM60393.1 - 2.2 7.8 5.5 2.9 7.4 0.8 2.9 2 0 0 2 2 2 0 Mu-like prophage protein Com Trm112p PF03966.16 KUM60393.1 - 3.2 8.4 5.8 20 5.8 0.4 3.4 3 0 0 3 3 3 0 Trm112p-like protein Ribosomal_S7e PF01251.18 KUM60394.1 - 1.1e-82 276.3 0.1 1.4e-82 275.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e DUF1382 PF07131.11 KUM60394.1 - 0.059 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) Ras PF00071.22 KUM60395.1 - 3e-56 189.5 0.0 4e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM60395.1 - 1.5e-34 118.8 0.0 2.9e-34 117.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM60395.1 - 2.9e-14 52.9 0.0 4.7e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KUM60395.1 - 1.5e-05 24.6 0.0 3e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KUM60395.1 - 6.8e-05 22.3 0.0 7.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KUM60395.1 - 8e-05 22.7 0.1 0.00019 21.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KUM60395.1 - 0.00045 20.7 0.1 0.00081 19.8 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KUM60395.1 - 0.074 13.0 0.0 2.7 7.9 0.0 2.5 2 1 1 3 3 3 0 RsgA GTPase 6PGD PF00393.19 KUM60397.1 - 1.5e-79 267.5 0.0 1.9e-79 267.1 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KUM60397.1 - 5.6e-34 117.6 0.0 3.7e-33 114.9 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KUM60397.1 - 3.4e-05 23.8 0.0 6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KUM60397.1 - 0.00012 22.1 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 KUM60397.1 - 0.00047 19.6 0.0 0.0008 18.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KUM60397.1 - 0.0006 19.4 0.0 0.0021 17.7 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TehB PF03848.14 KUM60397.1 - 0.02 14.3 0.2 0.082 12.3 0.0 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TehB F420_oxidored PF03807.17 KUM60397.1 - 0.027 15.0 0.0 0.067 13.8 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KUM60397.1 - 0.034 13.4 0.0 0.068 12.5 0.0 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KUM60397.1 - 0.055 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM60397.1 - 0.06 13.9 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_11 PF14833.6 KUM60397.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase AP_endonuc_2 PF01261.24 KUM60399.1 - 2.7e-34 118.4 0.0 3.4e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel adh_short_C2 PF13561.6 KUM60400.1 - 4.4e-14 52.6 0.0 5.8e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM60400.1 - 1.4e-12 47.5 0.0 4.5e-12 45.8 0.0 1.7 1 1 1 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 KUM60400.1 - 0.00024 20.7 0.0 0.00028 20.4 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KUM60400.1 - 0.00046 19.4 0.0 0.00062 18.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 KUM60400.1 - 0.0037 16.7 0.0 0.0092 15.4 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KUM60400.1 - 0.015 15.2 0.1 0.052 13.4 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H-binding NmrA PF05368.13 KUM60400.1 - 0.021 14.4 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family KR PF08659.10 KUM60400.1 - 0.026 14.4 0.0 0.08 12.9 0.0 1.8 1 1 0 1 1 1 0 KR domain DUF3173 PF11372.8 KUM60400.1 - 0.055 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) ocr PF08684.10 KUM60400.1 - 0.068 13.6 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 DNA mimic ocr 3HCDH_N PF02737.18 KUM60400.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KUM60401.1 - 7e-11 42.0 0.1 1.8e-09 37.4 0.2 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KUM60401.1 - 3.1e-08 33.7 0.3 5.1e-06 26.5 0.2 2.2 1 1 1 2 2 2 2 NAD(P)H-binding 3Beta_HSD PF01073.19 KUM60401.1 - 7e-08 31.8 0.9 1.5e-07 30.7 0.9 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KUM60401.1 - 6.9e-06 25.8 0.5 1.2e-05 25.0 0.5 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KUM60401.1 - 7.8e-06 25.5 0.2 1.2e-05 24.9 0.2 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KUM60401.1 - 0.0027 16.9 0.1 0.0044 16.2 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KUM60401.1 - 0.004 16.3 0.3 0.039 13.1 0.1 2.4 2 1 1 3 3 3 1 Male sterility protein Polysacc_synt_2 PF02719.15 KUM60401.1 - 0.0043 16.2 0.1 0.0068 15.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.18 KUM60401.1 - 0.013 15.7 0.3 0.027 14.8 0.3 1.5 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.10 KUM60401.1 - 0.019 14.9 0.4 0.03 14.2 0.4 1.3 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 KUM60401.1 - 0.067 12.6 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase PMI_typeI PF01238.21 KUM60403.1 - 2.1e-49 168.7 0.0 2.9e-26 92.5 0.0 2.0 1 1 0 2 2 2 2 Phosphomannose isomerase type I AraC_N PF06719.13 KUM60403.1 - 0.0078 15.9 0.0 0.024 14.3 0.0 1.7 2 0 0 2 2 2 1 AraC-type transcriptional regulator N-terminus Cupin_2 PF07883.11 KUM60403.1 - 0.036 13.8 0.1 8.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Cupin domain Caleosin PF05042.13 KUM60405.1 - 6.4e-69 231.2 0.0 8.5e-69 230.8 0.0 1.2 1 0 0 1 1 1 1 Caleosin related protein EF-hand_1 PF00036.32 KUM60405.1 - 4.7e-05 22.6 4.6 0.00016 21.0 0.1 2.7 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KUM60405.1 - 0.00067 19.4 5.3 0.0012 18.6 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 KUM60405.1 - 0.0016 18.2 0.1 0.058 13.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KUM60405.1 - 0.02 14.4 0.2 0.02 14.4 0.2 2.7 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.6 KUM60405.1 - 0.023 15.2 0.0 0.12 12.8 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair PaaX_C PF08223.11 KUM60407.1 - 0.073 13.4 0.1 0.24 11.7 0.1 1.9 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain AAA PF00004.29 KUM60408.1 - 4.6e-16 59.5 0.0 1.9e-15 57.5 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KUM60408.1 - 0.00035 21.0 0.1 0.0016 18.9 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KUM60408.1 - 0.00035 20.8 0.0 0.0019 18.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KUM60408.1 - 0.0028 17.7 0.0 0.0086 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KUM60408.1 - 0.03 14.1 0.6 0.093 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KUM60408.1 - 0.031 14.5 0.0 0.15 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KUM60408.1 - 0.044 13.5 0.3 0.62 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Caleosin PF05042.13 KUM60408.1 - 0.14 12.1 0.1 0.4 10.6 0.1 1.8 1 0 0 1 1 1 0 Caleosin related protein ATPase PF06745.13 KUM60408.1 - 0.16 11.3 0.1 0.32 10.3 0.1 1.4 1 0 0 1 1 1 0 KaiC MFS_1 PF07690.16 KUM60411.1 - 2.5e-39 135.2 42.8 2.5e-39 135.2 42.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM60411.1 - 3.9e-10 39.2 9.6 3.9e-10 39.2 9.6 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter Fungal_trans PF04082.18 KUM60412.1 - 3e-11 42.9 0.7 1.5e-10 40.6 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60412.1 - 2.1e-08 34.1 6.4 4.4e-08 33.1 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 KUM60413.1 - 1.2e-79 268.5 0.0 1.5e-79 268.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KUM60413.1 - 9.9e-07 28.8 0.1 4.7e-06 26.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KUM60413.1 - 0.0035 16.8 0.5 0.0059 16.1 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KUM60413.1 - 0.27 10.0 0.0 8.3 5.2 0.0 2.0 2 0 0 2 2 2 0 Steryl acetyl hydrolase CTD PF12815.7 KUM60413.1 - 0.32 11.6 0.1 0.32 11.6 0.1 2.8 3 0 0 3 3 3 0 Spt5 C-terminal nonapeptide repeat binding Spt4 MFS_1 PF07690.16 KUM60414.1 - 5.2e-34 117.7 34.1 6.3e-34 117.4 34.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KUM60414.1 - 1.1e-07 31.6 7.2 1.1e-07 31.6 7.2 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Amidase PF01425.21 KUM60415.1 - 9.2e-50 169.9 0.0 1.1e-46 159.7 0.0 2.3 1 1 1 2 2 2 2 Amidase COesterase PF00135.28 KUM60416.1 - 3.4e-102 343.0 0.0 4.1e-102 342.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KUM60416.1 - 2.1e-08 34.3 0.9 1.3e-07 31.7 0.4 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Glyco_hydro_28 PF00295.17 KUM60419.1 - 4.2e-31 108.2 0.8 5.5e-31 107.8 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 KUM60419.1 - 9.6e-08 32.1 7.5 8e-07 29.1 2.4 3.5 1 1 2 3 3 3 1 Pectate lyase superfamily protein NFACT-C PF11923.8 KUM60421.1 - 2e-40 137.0 0.2 2e-40 137.0 0.2 3.7 4 0 0 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 KUM60421.1 - 1.6e-34 119.5 11.9 1.6e-34 119.5 11.9 2.5 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KUM60421.1 - 5.8e-27 94.5 0.0 1.3e-26 93.4 0.0 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain Glyco_transf_28 PF03033.20 KUM60422.1 - 3.5e-20 72.5 0.0 1.1e-19 70.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KUM60422.1 - 0.00011 21.1 0.0 0.00018 20.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 KUM60422.1 - 0.01 15.6 1.9 0.059 13.1 0.8 2.2 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal Glyco_tran_28_C PF04101.16 KUM60422.1 - 0.029 14.4 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DUF2985 PF11204.8 KUM60423.1 - 8.3e-32 109.2 3.3 8.3e-32 109.2 3.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) MerC PF03203.14 KUM60423.1 - 0.07 13.6 2.7 0.13 12.7 0.1 2.2 2 0 0 2 2 2 0 MerC mercury resistance protein Fungal_trans_2 PF11951.8 KUM60424.1 - 1.3e-56 192.1 3.2 1.6e-56 191.8 3.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain CRISPR_Cas2 PF09827.9 KUM60424.1 - 0.076 13.2 0.5 9.6 6.5 0.1 2.6 1 1 0 2 2 2 0 CRISPR associated protein Cas2 Clat_adaptor_s PF01217.20 KUM60425.1 - 9.2e-11 41.9 0.0 2.7e-10 40.3 0.1 1.6 2 0 0 2 2 2 1 Clathrin adaptor complex small chain FapA PF03961.13 KUM60426.1 - 1.9 7.0 14.7 3.8 6.0 14.2 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF948 PF06103.11 KUM60426.1 - 2.4 8.5 3.7 0.7 10.2 0.6 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF812 PF05667.11 KUM60426.1 - 3.4 6.4 25.9 16 4.2 22.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Sulfatase PF00884.23 KUM60427.1 - 4.4e-44 151.1 0.9 2e-41 142.4 0.2 2.5 2 1 0 2 2 2 1 Sulfatase DUF4976 PF16347.5 KUM60427.1 - 1.8e-08 34.6 1.5 1.2e-07 32.0 0.2 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KUM60427.1 - 1e-06 28.6 0.0 0.00039 20.1 0.0 2.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 KUM60427.1 - 0.0012 19.6 0.0 0.0024 18.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 KUM60427.1 - 0.0069 15.5 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF229 PF02995.17 KUM60427.1 - 0.071 11.7 0.0 0.096 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Glyco_hydro_5_C PF18564.1 KUM60428.1 - 1.2e-19 70.6 0.0 2.8e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KUM60428.1 - 3.8e-06 26.5 2.9 2.7e-05 23.8 1.9 2.4 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) FMO-like PF00743.19 KUM60429.1 - 9.8e-11 40.8 0.0 4.5e-09 35.3 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KUM60429.1 - 1.1e-09 38.3 0.0 2.9e-07 30.6 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KUM60429.1 - 3.6e-06 26.4 0.0 0.011 15.0 0.0 3.1 3 0 0 3 3 3 2 Thi4 family Pyr_redox_3 PF13738.6 KUM60429.1 - 7.6e-06 25.4 0.0 0.00014 21.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM60429.1 - 1.9e-05 24.0 0.0 0.0046 16.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KUM60429.1 - 8.2e-05 22.3 0.0 0.017 14.8 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM60429.1 - 0.00012 21.4 0.0 0.018 14.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM60429.1 - 0.0013 18.8 0.2 0.23 11.4 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KUM60429.1 - 0.0014 18.7 0.0 0.024 14.7 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KUM60429.1 - 0.004 16.5 0.0 0.007 15.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KUM60429.1 - 0.029 14.8 0.0 0.079 13.4 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Dyp_perox PF04261.12 KUM60430.1 - 4.4e-87 292.1 0.0 5.1e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family adh_short_C2 PF13561.6 KUM60431.1 - 7.1e-60 202.5 0.5 1.1e-59 201.9 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM60431.1 - 2.8e-48 164.0 0.2 4.9e-48 163.2 0.2 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM60431.1 - 2.2e-14 53.8 0.8 3.2e-13 50.0 0.8 2.1 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KUM60431.1 - 1.8e-07 30.6 0.1 4.3e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KUM60431.1 - 0.0025 17.3 0.2 0.0088 15.5 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Adeno_PIX PF03955.14 KUM60431.1 - 0.035 14.3 0.1 0.095 12.9 0.1 1.7 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) DLH PF01738.18 KUM60432.1 - 0.0051 16.4 0.0 0.0051 16.4 0.0 1.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Sua5_yciO_yrdC PF01300.18 KUM60433.1 - 3e-55 186.5 0.0 4.8e-55 185.8 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KUM60433.1 - 6.5e-32 110.9 0.0 1.2e-31 110.1 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding A_deaminase PF00962.22 KUM60434.1 - 2.1e-80 270.5 0.0 2.4e-80 270.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KUM60434.1 - 0.0072 15.7 0.1 0.052 12.9 0.0 2.3 2 1 0 2 2 2 1 Amidohydrolase family Ribosomal_L16 PF00252.18 KUM60435.1 - 7.3e-45 152.2 0.1 9.9e-45 151.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e MFS_1 PF07690.16 KUM60436.1 - 4.6e-18 65.3 19.1 6.4e-18 64.8 19.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PQ-loop PF04193.14 KUM60437.1 - 3.4e-36 122.8 10.5 4e-19 68.1 1.2 3.2 3 0 0 3 3 3 2 PQ loop repeat CYSTM PF12734.7 KUM60437.1 - 0.00068 19.9 0.0 0.0027 18.0 0.1 1.9 2 0 0 2 2 2 1 Cysteine-rich TM module stress tolerance Pro_dh PF01619.18 KUM60438.1 - 2.8e-64 217.5 0.2 3.2e-64 217.3 0.2 1.0 1 0 0 1 1 1 1 Proline dehydrogenase Me-amine-dh_L PF02975.14 KUM60439.1 - 0.0027 18.2 0.1 0.0035 17.8 0.1 1.2 1 0 0 1 1 1 1 Methylamine dehydrogenase, L chain Fungal_trans PF04082.18 KUM60440.1 - 5.3e-09 35.5 0.9 2.5e-08 33.3 0.9 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60440.1 - 1.6e-07 31.3 12.5 1.6e-07 31.3 12.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR PF01535.20 KUM60441.1 - 0.14 12.5 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 PPR repeat RabGAP-TBC PF00566.18 KUM60442.1 - 9.5e-15 54.8 0.1 1.4e-14 54.3 0.1 1.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DAO PF01266.24 KUM60445.1 - 4e-29 102.3 0.0 4.8e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KUM60445.1 - 5.2e-05 23.4 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KUM60445.1 - 0.0019 17.5 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM60445.1 - 0.055 14.0 0.0 0.21 12.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KUM60445.1 - 0.085 12.1 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain Aldedh PF00171.22 KUM60446.1 - 2e-95 320.0 0.0 2.3e-95 319.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sugar_tr PF00083.24 KUM60447.1 - 3.5e-100 336.0 18.2 4.3e-100 335.7 18.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM60447.1 - 8.7e-24 84.1 36.4 4.1e-13 49.0 13.5 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily zf-LITAF-like PF10601.9 KUM60447.1 - 0.21 11.9 3.9 1.7 9.0 0.1 3.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Trp_oprn_chp PF09534.10 KUM60447.1 - 0.8 9.5 9.1 0.16 11.7 1.9 2.8 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Cpn60_TCP1 PF00118.24 KUM60448.1 - 3.3e-152 507.6 4.3 3.8e-152 507.4 4.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.11 KUM60448.1 - 0.014 15.8 0.0 1.6 9.2 0.1 2.8 2 0 0 2 2 2 0 Replication factor C C-terminal domain FtsA PF14450.6 KUM60448.1 - 0.076 13.4 1.0 0.2 12.1 0.8 1.8 1 1 0 1 1 1 0 Cell division protein FtsA Beta_helix_2 PF18835.1 KUM60448.1 - 0.17 11.7 0.2 3.6 7.4 0.3 2.6 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase Peptidase_C14 PF00656.22 KUM60449.1 - 1.8e-63 214.8 0.0 2.3e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain MFS_1 PF07690.16 KUM60450.1 - 3.6e-20 72.2 37.8 3.6e-20 72.2 37.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM60450.1 - 2.8e-10 39.6 5.8 2.8e-10 39.6 5.8 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter DUF1129 PF06570.11 KUM60450.1 - 0.22 11.0 1.4 0.5 9.8 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) JHD PF17811.1 KUM60451.1 - 0.092 13.3 0.2 0.29 11.7 0.1 1.8 2 0 0 2 2 2 0 Jumonji helical domain zf-H2C2 PF09337.10 KUM60452.1 - 1.6e-15 57.0 1.8 2.9e-15 56.2 1.8 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KUM60452.1 - 2.2e-10 40.5 0.5 4.2e-10 39.6 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KUM60452.1 - 7.1e-06 26.2 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KUM60452.1 - 0.031 14.9 0.0 0.086 13.5 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KUM60452.1 - 0.093 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein eRF1_1 PF03463.15 KUM60453.1 - 4.7e-46 156.0 0.0 7.1e-46 155.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 KUM60453.1 - 2e-20 73.3 0.0 3.8e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 KUM60453.1 - 2.9e-19 69.7 0.0 4.5e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Aldo_ket_red PF00248.21 KUM60454.1 - 1.1e-36 126.5 0.1 3.1e-34 118.5 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 KUM60455.1 - 3e-56 190.7 0.0 4.5e-56 190.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM60455.1 - 5.5e-20 71.7 0.0 8.7e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KUM60455.1 - 9.8e-05 21.8 0.1 0.00023 20.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KUM60455.1 - 0.00022 20.6 0.0 0.0008 18.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KUM60455.1 - 0.0003 20.8 0.1 0.014 15.3 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KUM60455.1 - 0.0012 17.8 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KUM60455.1 - 0.018 14.6 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KUM60455.1 - 0.026 13.3 0.0 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Wtap PF17098.5 KUM60456.1 - 0.07 13.1 0.3 0.14 12.1 0.3 1.4 1 0 0 1 1 1 0 WTAP/Mum2p family PTS_2-RNA PF01885.16 KUM60457.1 - 8.5e-70 234.5 0.0 1.1e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF1778 PF08681.11 KUM60457.1 - 0.15 12.0 0.4 3 7.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1778) Dioxygenase_C PF00775.21 KUM60458.1 - 2.8e-48 163.8 0.0 3.7e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KUM60458.1 - 3.2e-26 91.0 0.2 4.9e-26 90.4 0.2 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KUM60458.1 - 8.4e-06 26.0 0.0 3.7e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KUM60458.1 - 0.0095 15.9 0.0 0.66 10.0 0.0 2.7 3 0 0 3 3 3 1 CarboxypepD_reg-like domain SpaA PF17802.1 KUM60458.1 - 0.036 14.4 0.1 0.092 13.1 0.0 1.7 2 0 0 2 2 2 0 Prealbumin-like fold domain Lipase_C PF18067.1 KUM60458.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipase C-terminal domain DUF4198 PF10670.9 KUM60458.1 - 0.083 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Abhydrolase_1 PF00561.20 KUM60459.1 - 5.9e-23 81.8 0.1 3.7e-19 69.4 0.2 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM60459.1 - 1.2e-18 67.2 0.1 4e-18 65.6 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KUM60459.1 - 5e-14 53.4 0.0 7.6e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KUM60459.1 - 1.7e-06 26.9 0.0 2.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 KUM60459.1 - 0.00014 21.6 0.1 0.00026 20.7 0.1 1.4 1 1 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 KUM60459.1 - 0.00016 21.6 0.0 0.00038 20.5 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KUM60459.1 - 0.0004 20.3 0.1 0.26 11.1 0.0 2.5 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KUM60459.1 - 0.0013 18.2 0.0 0.33 10.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KUM60459.1 - 0.0029 17.2 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family PGAP1 PF07819.13 KUM60459.1 - 0.0068 16.1 3.6 0.031 14.0 1.4 2.4 2 1 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.20 KUM60459.1 - 0.0076 16.4 0.0 0.011 15.9 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 KUM60459.1 - 0.0085 15.9 0.0 0.037 13.8 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 KUM60459.1 - 0.026 14.4 0.1 0.2 11.5 0.0 2.0 1 1 1 2 2 2 0 Serine hydrolase DUF915 PF06028.11 KUM60459.1 - 0.028 13.8 0.0 0.25 10.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 KUM60459.1 - 0.037 13.5 0.2 0.15 11.5 0.1 2.0 1 1 1 2 2 2 0 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.7 KUM60459.1 - 0.038 12.9 0.9 0.16 10.9 0.9 1.9 1 1 0 1 1 1 0 Chlorophyllase enzyme LIDHydrolase PF10230.9 KUM60459.1 - 0.08 12.5 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase PF00151.19 KUM60459.1 - 0.11 11.8 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Lipase UPF0227 PF05728.12 KUM60459.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) PAF-AH_p_II PF03403.13 KUM60459.1 - 0.16 10.4 0.2 4.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II NARP1 PF12569.8 KUM60460.1 - 0.86 8.4 8.3 1.4 7.7 8.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 LRR_6 PF13516.6 KUM60461.1 - 2.9e-12 45.6 3.4 0.049 13.7 0.0 6.9 8 0 0 8 8 8 3 Leucine Rich repeat F-box-like PF12937.7 KUM60461.1 - 8.4e-11 41.6 0.0 3.8e-10 39.5 0.0 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KUM60461.1 - 1.4e-07 31.2 0.0 1.3e-06 28.1 0.0 2.9 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.7 KUM60461.1 - 5.9e-06 26.5 6.6 0.032 14.7 0.0 4.6 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) Nucleo_P87 PF07267.11 KUM60461.1 - 0.0035 16.3 0.1 0.0049 15.8 0.1 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 PRANC PF09372.10 KUM60461.1 - 0.2 12.0 0.0 0.73 10.2 0.0 2.0 2 0 0 2 2 2 0 PRANC domain LRR_1 PF00560.33 KUM60461.1 - 0.61 10.8 12.2 13 6.8 0.1 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat Efg1 PF10153.9 KUM60463.1 - 4.2e-32 110.9 9.6 4.2e-32 110.9 9.6 2.8 3 0 0 3 3 3 1 rRNA-processing protein Efg1 zinc_ribbon_16 PF17034.5 KUM60464.1 - 9.5e-24 84.0 9.5 9.5e-24 84.0 9.5 2.1 2 0 0 2 2 2 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KUM60464.1 - 0.065 12.9 12.4 0.025 14.2 8.2 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KUM60464.1 - 0.09 13.1 7.0 0.027 14.8 3.2 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain AOX PF01786.17 KUM60465.1 - 2.6e-90 301.7 0.2 3.1e-90 301.5 0.2 1.0 1 0 0 1 1 1 1 Alternative oxidase BCS1_N PF08740.11 KUM60467.1 - 6.5e-49 166.5 1.8 6.5e-49 166.5 1.8 1.8 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KUM60467.1 - 8e-19 68.4 0.0 6.5e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KUM60467.1 - 0.005 17.3 0.3 0.02 15.3 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KUM60467.1 - 0.018 14.6 0.0 0.062 12.9 0.0 1.8 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 KUM60467.1 - 0.033 13.4 0.0 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATPase PF06745.13 KUM60467.1 - 0.034 13.5 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.6 KUM60467.1 - 0.11 12.3 0.1 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF810 PF05664.11 KUM60468.1 - 0.0026 16.4 0.6 0.0038 15.8 0.6 1.3 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) Cep57_MT_bd PF06657.13 KUM60468.1 - 0.053 14.0 0.5 0.21 12.1 0.2 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ORF6C PF10552.9 KUM60468.1 - 0.22 11.6 3.5 0.74 9.9 0.3 2.8 3 0 0 3 3 3 0 ORF6C domain Retrotrans_gag PF03732.17 KUM60468.1 - 1.1 9.6 3.8 1.4 9.3 1.0 2.5 3 1 0 3 3 3 0 Retrotransposon gag protein MFS_1 PF07690.16 KUM60471.1 - 1.2e-47 162.6 63.0 1.7e-46 158.8 63.0 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM60471.1 - 2.4e-16 59.3 18.1 2.4e-16 59.3 18.1 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM60471.1 - 5.5e-11 42.0 41.0 7.5e-11 41.5 14.2 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter PrgH PF09480.10 KUM60471.1 - 0.068 12.5 0.5 0.13 11.5 0.5 1.4 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) XH PF03469.14 KUM60472.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 XH domain DUF3533 PF12051.8 KUM60473.1 - 8e-93 311.4 14.7 9.8e-93 311.1 14.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) adh_short PF00106.25 KUM60474.1 - 9.6e-49 165.5 0.5 1.2e-48 165.2 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM60474.1 - 2.1e-41 142.0 0.5 2.7e-41 141.7 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM60474.1 - 8.7e-11 42.0 0.2 1.2e-10 41.6 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM60474.1 - 2.1e-07 30.6 0.2 4.3e-07 29.6 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KUM60474.1 - 1.7e-05 24.8 0.5 2.3e-05 24.3 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 KUM60474.1 - 4.4e-05 23.0 0.0 6.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 KUM60474.1 - 0.00031 19.9 0.1 0.00044 19.5 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.17 KUM60474.1 - 0.00046 20.7 0.3 0.001 19.6 0.3 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 KUM60474.1 - 0.00073 19.2 0.3 0.0012 18.4 0.3 1.4 1 0 0 1 1 1 1 NmrA-like family 3HCDH_N PF02737.18 KUM60474.1 - 0.1 12.5 0.2 0.2 11.6 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RibD_C PF01872.17 KUM60475.1 - 1.6e-33 116.2 0.0 1.8e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain ELK PF03789.13 KUM60475.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 ELK domain MFS_1 PF07690.16 KUM60476.1 - 4.6e-23 81.7 22.4 2e-22 79.6 22.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KUM60476.1 - 9.4e-05 21.4 2.8 0.00016 20.6 2.4 1.6 1 1 0 1 1 1 1 MFS_1 like family DUF308 PF03729.13 KUM60476.1 - 0.042 14.2 6.0 0.19 12.0 6.0 2.2 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) Glyco_hydro_43 PF04616.14 KUM60477.1 - 3e-36 125.2 0.0 4e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KUM60477.1 - 0.064 12.8 1.3 0.094 12.3 0.1 1.8 2 1 0 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain MFS_1 PF07690.16 KUM60478.1 - 5.4e-32 111.1 37.0 5.4e-32 111.1 37.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 KUM60478.1 - 0.58 10.0 3.9 6.7 6.6 0.2 2.6 2 0 0 2 2 2 0 Bacteriophage holin family HP1 DSBA PF01323.20 KUM60479.1 - 5.3e-13 49.2 0.0 6.1e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Phosphodiest PF01663.22 KUM60480.1 - 8.1e-89 298.7 0.6 1.1e-88 298.3 0.6 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KUM60480.1 - 8.3e-05 22.1 0.1 0.085 12.2 0.0 2.3 2 0 0 2 2 2 2 Sulfatase PglZ PF08665.12 KUM60480.1 - 0.2 11.7 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 PglZ domain Pex14_N PF04695.13 KUM60480.1 - 2.9 8.5 13.7 45 4.7 0.0 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.32 KUM60481.1 - 1.4e-71 234.6 18.6 3.1e-11 43.6 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Pkinase PF00069.25 KUM60481.1 - 1.8e-44 152.1 0.0 2.7e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ANAPC4_WD40 PF12894.7 KUM60481.1 - 4.9e-26 90.9 0.3 0.0045 17.3 0.0 7.2 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Pkinase_Tyr PF07714.17 KUM60481.1 - 4.7e-24 85.1 0.0 6.6e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ge1_WD40 PF16529.5 KUM60481.1 - 3.5e-15 55.8 4.4 0.025 13.6 0.0 7.1 1 1 6 7 7 7 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KUM60481.1 - 3.2e-08 33.3 0.8 15 5.6 0.0 7.0 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KUM60481.1 - 7.5e-07 29.2 0.4 0.0023 17.9 0.0 3.3 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KUM60481.1 - 3.8e-05 22.4 0.4 0.18 10.3 0.0 2.7 1 1 0 2 2 2 2 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 KUM60481.1 - 0.00024 20.2 3.9 0.97 8.3 0.0 4.5 1 1 3 5 5 5 1 Partner and localizer of BRCA2 WD40 domain IKI3 PF04762.12 KUM60481.1 - 0.002 16.2 0.0 0.26 9.2 0.0 2.9 2 1 0 3 3 3 1 IKI3 family WD40_like PF17005.5 KUM60481.1 - 0.0025 17.2 0.0 7 5.9 0.0 4.2 2 2 3 5 5 5 1 WD40-like domain EBP PF05241.12 KUM60481.1 - 0.0035 16.8 0.1 4.9 6.6 0.0 3.5 2 1 1 3 3 3 1 Emopamil binding protein Kdo PF06293.14 KUM60481.1 - 0.0043 16.4 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nup160 PF11715.8 KUM60481.1 - 0.0084 14.8 6.7 0.81 8.3 0.1 4.2 2 2 2 4 4 4 1 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 KUM60481.1 - 0.01 15.5 13.3 12 5.7 0.0 7.2 8 0 0 8 8 7 0 Proteasome subunit A N-terminal signature SGL PF08450.12 KUM60481.1 - 0.039 13.5 0.4 0.1 12.1 0.2 1.8 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region DUF5114 PF17141.4 KUM60481.1 - 0.079 13.5 0.8 20 5.8 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF5114) DUF5122 PF17164.4 KUM60481.1 - 4 7.8 4.6 17 5.8 0.0 3.8 5 0 0 5 5 3 0 Domain of unknown function (DUF5122) beta-propeller HLH PF00010.26 KUM60483.1 - 1.5e-14 53.7 0.2 4.5e-14 52.1 0.2 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4587 PF15248.6 KUM60483.1 - 0.025 15.4 8.4 0.37 11.6 0.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4587) DUF3752 PF12572.8 KUM60483.1 - 0.071 13.6 3.6 1.7 9.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3752) Ank_2 PF12796.7 KUM60484.1 - 1.6e-27 95.9 8.7 5.4e-09 36.5 0.0 5.7 3 3 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM60484.1 - 5.2e-27 93.9 9.4 2.6e-07 31.1 0.1 8.5 7 4 3 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM60484.1 - 1.6e-26 89.4 6.7 0.00029 21.0 0.0 10.8 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.6 KUM60484.1 - 2.1e-22 78.9 3.8 4.2e-08 33.3 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KUM60484.1 - 3.6e-18 65.1 6.9 0.00029 21.2 0.1 8.6 8 2 0 8 8 8 4 Ankyrin repeat FAD_binding_4 PF01565.23 KUM60485.1 - 7.9e-23 80.7 1.4 1.6e-22 79.8 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain Fungal_trans_2 PF11951.8 KUM60486.1 - 2.6e-11 43.0 0.6 9.6e-10 37.8 0.0 2.1 1 1 0 2 2 2 2 Fungal specific transcription factor domain BTB PF00651.31 KUM60487.1 - 0.00067 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF2797 PF10977.8 KUM60487.1 - 0.12 12.3 0.5 0.22 11.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Fungal_trans PF04082.18 KUM60488.1 - 1.9e-13 50.1 0.2 4.4e-13 48.9 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60489.1 - 1.6e-10 41.0 13.1 2.5e-10 40.3 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM60490.1 - 3.9e-25 88.4 0.0 1.6e-24 86.4 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Peptidase_M41 PF01434.18 KUM60491.1 - 5.3e-66 222.1 0.0 8.8e-66 221.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KUM60491.1 - 1.6e-42 145.0 0.0 3.5e-42 143.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KUM60491.1 - 1.7e-12 46.9 0.2 3.8e-12 45.8 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KUM60491.1 - 1.8e-12 47.5 0.7 3.1e-12 46.8 0.0 1.8 2 0 0 2 2 1 1 FtsH Extracellular AAA_5 PF07728.14 KUM60491.1 - 0.00063 19.8 0.0 0.0023 17.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KUM60491.1 - 0.0032 17.9 0.0 0.21 12.0 0.1 2.9 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KUM60491.1 - 0.0076 16.0 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KUM60491.1 - 0.0098 15.1 0.1 0.021 14.0 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KUM60491.1 - 0.016 15.5 0.1 1.2 9.4 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 KUM60491.1 - 0.042 14.0 0.0 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KUM60491.1 - 0.06 13.1 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein CDC45 PF02724.14 KUM60491.1 - 0.34 9.2 3.0 0.45 8.7 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2201_N PF13203.6 KUM60491.1 - 0.47 10.0 4.6 0.87 9.1 4.6 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Presenilin PF01080.17 KUM60491.1 - 1.5 7.5 5.8 2.4 6.8 5.8 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KUM60491.1 - 5.2 6.8 9.1 10 5.9 9.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HNH_2 PF13391.6 KUM60492.1 - 1.5e-09 37.9 0.0 3.2e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease DUF1295 PF06966.12 KUM60493.1 - 4.2e-37 127.9 7.7 5.3e-37 127.6 7.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Topoisom_bac PF01131.20 KUM60494.1 - 1.1e-101 340.9 0.0 1.4e-101 340.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KUM60494.1 - 1.5e-18 66.9 0.0 7.6e-18 64.6 0.0 2.2 2 0 0 2 2 2 1 Toprim domain SLATT_fungal PF18142.1 KUM60495.1 - 1.7 8.7 3.8 2.3 8.2 0.0 2.6 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain NOA36 PF06524.12 KUM60496.1 - 0.017 14.5 12.4 0.022 14.1 12.4 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 KUM60496.1 - 0.021 15.1 15.0 0.025 14.8 15.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PTPRCAP PF15713.5 KUM60496.1 - 0.028 14.7 7.7 0.037 14.3 7.7 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PPP4R2 PF09184.11 KUM60496.1 - 0.31 10.6 11.7 0.36 10.4 11.7 1.1 1 0 0 1 1 1 0 PPP4R2 DUF4820 PF16091.5 KUM60496.1 - 0.95 8.8 2.9 1.1 8.6 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Nop14 PF04147.12 KUM60496.1 - 1.8 6.7 15.0 2 6.6 15.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KUM60496.1 - 1.8 7.9 14.2 2 7.8 14.2 1.1 1 0 0 1 1 1 0 SDA1 HAMP PF00672.25 KUM60500.1 - 8.2e-44 147.8 14.1 1.3e-08 35.1 0.4 7.3 6 1 0 6 6 6 5 HAMP domain HATPase_c PF02518.26 KUM60500.1 - 8.6e-33 113.2 0.2 3.4e-32 111.3 0.2 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KUM60500.1 - 5.3e-26 91.0 0.5 2.7e-25 88.7 0.5 2.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KUM60500.1 - 9.9e-17 60.7 3.8 3e-16 59.2 0.2 3.8 4 0 0 4 4 3 1 His Kinase A (phospho-acceptor) domain APG17 PF04108.12 KUM60500.1 - 1.5e-14 53.9 7.0 0.0094 15.1 0.0 5.9 1 1 2 4 4 4 3 Autophagy protein Apg17 Syntaxin_2 PF14523.6 KUM60500.1 - 1.4e-06 28.6 19.7 1.1 9.7 0.1 7.2 3 2 3 6 6 6 2 Syntaxin-like protein DUF4279 PF14106.6 KUM60500.1 - 0.00027 21.1 0.7 7.5 6.8 0.0 5.6 6 1 0 6 6 6 1 Domain of unknown function (DUF4279) DUF1843 PF08898.10 KUM60500.1 - 0.00093 19.6 7.2 15 6.2 0.1 6.0 5 1 0 5 5 5 0 Domain of unknown function (DUF1843) DUF948 PF06103.11 KUM60500.1 - 0.0028 17.9 57.2 1.1 9.6 0.2 10.1 4 2 2 6 6 6 1 Bacterial protein of unknown function (DUF948) Gp-FAR-1 PF05823.12 KUM60500.1 - 0.0093 16.3 5.6 18 5.7 0.1 5.0 1 1 3 5 5 5 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Fib_alpha PF08702.10 KUM60500.1 - 0.025 14.8 34.1 1.1 9.4 0.6 7.3 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family SpoIIID PF12116.8 KUM60500.1 - 0.026 14.6 4.7 22 5.2 0.0 5.3 5 0 0 5 5 5 0 Stage III sporulation protein D NOD PF06816.13 KUM60500.1 - 0.043 13.4 0.0 6.2 6.5 0.0 2.8 2 0 0 2 2 2 0 NOTCH protein Cbl_N PF02262.16 KUM60500.1 - 0.055 13.5 0.1 3.3 7.7 0.1 2.9 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 IcmF_C PF06744.12 KUM60500.1 - 0.077 12.6 0.1 0.3 10.7 0.1 2.0 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal CMD PF02627.20 KUM60500.1 - 0.12 12.5 1.1 16 5.6 0.0 4.0 5 0 0 5 5 4 0 Carboxymuconolactone decarboxylase family DUF3829 PF12889.7 KUM60500.1 - 0.18 11.2 18.9 0.33 10.4 0.8 5.3 3 3 2 6 6 6 0 Protein of unknown function (DUF3829) MSA-2c PF12238.8 KUM60500.1 - 0.36 10.8 3.2 1.3 9.0 3.2 1.9 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF4795 PF16043.5 KUM60500.1 - 0.37 10.4 28.3 0.3 10.7 3.4 5.1 1 1 1 3 3 2 0 Domain of unknown function (DUF4795) BORCS6 PF10157.9 KUM60500.1 - 0.53 10.5 15.5 5.8 7.1 0.1 5.9 3 2 2 5 5 5 0 BLOC-1-related complex sub-unit 6 WXG100 PF06013.12 KUM60500.1 - 0.89 9.8 31.0 1.9 8.7 0.3 8.5 6 2 4 10 10 10 0 Proteins of 100 residues with WXG GLE1 PF07817.13 KUM60500.1 - 3.5 6.7 13.1 8.1 5.6 0.9 4.7 3 1 2 5 5 5 0 GLE1-like protein Mer2 PF09074.10 KUM60500.1 - 4.2 7.1 37.6 3 7.6 3.3 6.0 3 1 2 5 5 5 0 Mer2 Peptidase_C23 PF05379.11 KUM60500.1 - 9.4 6.4 6.7 14 5.9 0.2 3.9 4 0 0 4 4 4 0 Carlavirus endopeptidase Pam16 PF03656.13 KUM60501.1 - 3.8e-07 30.2 0.1 7.6e-07 29.2 0.1 1.6 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 KUM60501.1 - 1.2e-05 25.3 0.1 2e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 KUM60501.1 - 0.45 10.2 3.5 0.41 10.3 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Ribosomal_L24e PF01246.20 KUM60502.1 - 1.4e-27 95.7 6.4 4e-27 94.2 6.4 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e Diphthamide_syn PF01866.17 KUM60503.1 - 5e-86 288.9 0.0 7.4e-86 288.3 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Fe-ADH PF00465.19 KUM60504.1 - 3.2e-77 259.8 0.6 3.7e-77 259.6 0.6 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KUM60504.1 - 1.8e-15 57.3 0.4 2.5e-15 56.9 0.4 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase IMS_C PF11799.8 KUM60504.1 - 0.0033 18.1 0.0 0.26 12.0 0.0 2.5 1 1 0 2 2 2 1 impB/mucB/samB family C-terminal domain FAD_binding_4 PF01565.23 KUM60505.1 - 4.7e-20 71.7 4.2 9.6e-20 70.7 4.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KUM60505.1 - 3.1e-07 30.4 0.1 6.8e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like ANAPC4_WD40 PF12894.7 KUM60507.1 - 0.00027 21.2 0.0 0.093 13.0 0.0 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KUM60507.1 - 0.044 13.0 0.0 6.9 5.8 0.0 2.7 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.32 KUM60507.1 - 0.13 13.1 4.9 6.5 7.8 0.1 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat YL1 PF05764.13 KUM60507.1 - 0.3 11.2 7.5 0.5 10.4 7.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 KUM60507.1 - 5 5.3 6.3 7.1 4.8 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA_12 PF13087.6 KUM60508.1 - 2.2e-33 115.6 0.0 4.8e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KUM60508.1 - 8.2e-26 91.3 12.0 7.6e-15 55.4 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 KUM60508.1 - 3.6e-06 27.4 0.0 2.2e-05 24.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KUM60508.1 - 5e-06 26.4 0.1 3.5e-05 23.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_31 PF13614.6 KUM60508.1 - 0.00026 21.0 0.0 0.028 14.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KUM60508.1 - 0.00071 19.4 0.0 0.014 15.1 0.0 2.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KUM60508.1 - 0.0017 18.4 0.0 0.009 16.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 KUM60508.1 - 0.0021 17.9 0.0 0.0054 16.5 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Spectrin PF00435.21 KUM60508.1 - 0.012 16.0 5.3 0.04 14.4 4.6 2.2 2 0 0 2 2 2 0 Spectrin repeat DUF3552 PF12072.8 KUM60508.1 - 0.094 12.1 12.7 0.18 11.2 12.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Osmo_CC PF08946.10 KUM60508.1 - 0.29 11.4 7.7 1.6 9.0 0.4 3.9 3 1 1 4 4 4 0 Osmosensory transporter coiled coil AAA_23 PF13476.6 KUM60508.1 - 0.42 11.1 3.5 1.2 9.6 2.5 2.2 2 0 0 2 2 2 0 AAA domain APG6_N PF17675.1 KUM60508.1 - 0.75 10.3 15.4 0.089 13.3 10.3 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 KUM60508.1 - 0.84 9.2 6.9 2 8.0 6.9 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ABC_tran_CTD PF16326.5 KUM60508.1 - 2.3 8.5 6.4 7.4 6.9 6.4 1.9 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF2968 PF11180.8 KUM60508.1 - 7.7 6.1 16.9 0.52 9.9 11.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Glyco_hydro_7 PF00840.20 KUM60509.1 - 4e-208 691.5 16.0 4.5e-208 691.3 16.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF3472 PF11958.8 KUM60510.1 - 0.031 14.8 0.5 0.04 14.4 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3472) REPA_OB_2 PF16900.5 KUM60510.1 - 0.053 13.4 0.0 0.075 13.0 0.0 1.2 1 0 0 1 1 1 0 Replication protein A OB domain zf-C2H2_4 PF13894.6 KUM60511.1 - 0.0019 18.9 12.2 0.019 15.8 0.1 4.3 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KUM60511.1 - 0.012 16.0 0.1 0.012 16.0 0.1 3.6 3 1 0 3 3 3 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 KUM60511.1 - 0.79 10.4 5.7 0.98 10.1 0.0 2.8 3 0 0 3 3 3 0 FOXP coiled-coil domain MARVEL PF01284.23 KUM60516.1 - 1.3e-07 31.7 0.4 1.9e-07 31.2 0.4 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF898 PF05987.13 KUM60516.1 - 0.065 12.3 0.0 0.089 11.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) RAP1 PF07218.11 KUM60516.1 - 5.4 5.2 5.7 7.4 4.7 5.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Methyltransf_24 PF13578.6 KUM60518.1 - 1.6e-13 51.6 0.0 3.2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KUM60518.1 - 7.2e-13 48.2 0.0 1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase CmcI PF04989.12 KUM60518.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase GFO_IDH_MocA PF01408.22 KUM60519.1 - 1.7e-25 90.2 0.1 2.9e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KUM60519.1 - 1.2e-10 41.4 0.0 2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DapB_N PF01113.20 KUM60519.1 - 0.00095 19.3 0.1 0.0017 18.5 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.16 KUM60519.1 - 0.00098 19.8 0.0 0.0018 18.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 KUM60519.1 - 0.017 14.1 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family ABC_tran PF00005.27 KUM60520.1 - 1.2e-45 155.4 0.0 1.1e-21 77.7 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KUM60520.1 - 1.2e-20 73.3 2.1 1.2e-20 73.3 2.1 2.3 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 KUM60520.1 - 4.1e-18 66.2 0.1 0.00026 20.9 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KUM60520.1 - 1.5e-10 40.9 0.2 0.12 11.8 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KUM60520.1 - 4.3e-08 33.9 0.9 0.058 13.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KUM60520.1 - 8.1e-08 31.9 0.2 0.0038 16.9 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KUM60520.1 - 1.7e-06 28.0 0.4 0.042 13.5 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 KUM60520.1 - 9e-06 26.0 0.0 0.0043 17.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KUM60520.1 - 3.2e-05 24.4 0.0 0.099 13.0 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KUM60520.1 - 3.8e-05 24.0 0.0 0.19 12.0 0.2 2.8 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KUM60520.1 - 3.9e-05 23.7 0.1 0.024 14.7 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA PF00004.29 KUM60520.1 - 5.8e-05 23.5 0.1 0.85 10.1 0.0 3.5 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KUM60520.1 - 8.4e-05 23.1 0.0 0.11 13.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KUM60520.1 - 0.00011 22.5 0.1 2.2 8.7 0.0 3.6 4 0 0 4 4 3 2 RNA helicase NB-ARC PF00931.22 KUM60520.1 - 0.0002 20.6 0.0 0.81 8.8 0.0 3.2 2 1 0 2 2 2 2 NB-ARC domain RsgA_GTPase PF03193.16 KUM60520.1 - 0.00027 20.9 6.0 0.0052 16.7 0.1 2.9 4 0 0 4 4 2 1 RsgA GTPase AAA_5 PF07728.14 KUM60520.1 - 0.00036 20.6 0.1 1.4 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) NACHT PF05729.12 KUM60520.1 - 0.00053 20.0 0.3 0.8 9.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 KUM60520.1 - 0.00075 19.7 1.1 0.1 12.7 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.6 KUM60520.1 - 0.0035 17.4 0.0 3.7 7.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KUM60520.1 - 0.0037 17.0 2.4 1.8 8.3 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.6 KUM60520.1 - 0.0074 15.9 0.0 1.1 8.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 KUM60520.1 - 0.008 15.8 0.2 4.1 6.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KUM60520.1 - 0.01 15.3 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 KUM60520.1 - 0.015 15.5 0.8 5.4 7.2 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase ATP-synt_ab PF00006.25 KUM60520.1 - 0.029 14.0 0.0 0.26 10.9 0.0 2.5 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 KUM60520.1 - 0.055 13.4 0.2 3.5 7.5 0.1 2.5 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 KUM60520.1 - 0.055 13.2 0.9 3.9 7.1 0.0 3.1 4 0 0 4 4 3 0 AAA domain DUF87 PF01935.17 KUM60520.1 - 0.08 13.0 0.7 19 5.3 0.0 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain Rad17 PF03215.15 KUM60520.1 - 0.086 12.8 0.0 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain FeoB_N PF02421.18 KUM60520.1 - 0.13 11.7 0.0 4.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B ATPase_2 PF01637.18 KUM60520.1 - 0.14 12.1 0.3 24 4.7 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DUF2813 PF11398.8 KUM60520.1 - 0.22 10.8 1.7 17 4.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) AAA_17 PF13207.6 KUM60520.1 - 0.3 11.5 1.4 28 5.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain DAP3 PF10236.9 KUM60520.1 - 0.48 9.5 2.2 17 4.5 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 DUF3584 PF12128.8 KUM60520.1 - 3.5 5.0 8.4 0.23 8.9 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) AAA PF00004.29 KUM60521.1 - 3.3e-40 137.6 0.0 6e-40 136.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KUM60521.1 - 2.6e-10 39.9 0.5 4.8e-10 39.1 0.5 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KUM60521.1 - 1.3e-09 37.8 0.1 2.4e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 KUM60521.1 - 1.1e-05 25.8 0.2 0.018 15.3 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 KUM60521.1 - 1.6e-05 25.1 0.0 3.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KUM60521.1 - 2e-05 23.9 0.0 3.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KUM60521.1 - 6e-05 23.1 0.0 0.00018 21.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KUM60521.1 - 0.00045 20.6 0.4 0.0067 16.8 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KUM60521.1 - 0.00067 19.4 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KUM60521.1 - 0.0074 16.5 0.0 0.0074 16.5 0.0 1.9 3 0 0 3 3 1 1 AAA domain AAA_18 PF13238.6 KUM60521.1 - 0.0078 16.8 0.1 0.03 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KUM60521.1 - 0.015 14.8 0.6 0.52 9.7 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 KUM60521.1 - 0.016 15.4 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KUM60521.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 KUM60521.1 - 0.02 14.7 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KUM60521.1 - 0.024 13.8 0.1 0.057 12.6 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase PF06745.13 KUM60521.1 - 0.034 13.5 0.1 0.51 9.6 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_14 PF13173.6 KUM60521.1 - 0.035 14.1 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KUM60521.1 - 0.049 14.0 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KUM60521.1 - 0.061 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KUM60521.1 - 0.071 13.0 0.2 0.65 9.9 0.1 2.2 1 1 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KUM60521.1 - 0.091 12.3 0.1 0.4 10.2 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KUM60521.1 - 0.091 12.0 0.1 0.2 10.9 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KUM60521.1 - 0.11 12.0 0.3 0.46 10.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 KUM60521.1 - 0.15 11.7 0.5 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain DUF2075 PF09848.9 KUM60521.1 - 0.2 10.9 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KUM60521.1 - 0.27 10.9 2.0 0.33 10.6 0.3 2.1 2 1 0 2 2 2 0 AAA domain WD40 PF00400.32 KUM60522.1 - 5.9e-18 64.9 12.3 6.5e-06 26.8 0.7 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM60522.1 - 0.00059 20.1 0.0 0.21 11.9 0.0 3.4 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KUM60522.1 - 0.012 14.4 0.1 0.18 10.5 0.0 2.5 3 0 0 3 3 3 0 Nup133 N terminal like TFIIF_alpha PF05793.12 KUM60522.1 - 0.1 11.1 6.6 0.16 10.6 6.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GCIP PF13324.6 KUM60522.1 - 0.14 11.8 0.7 0.2 11.2 0.7 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting PBP1_TM PF14812.6 KUM60522.1 - 0.17 12.3 5.1 0.46 10.9 5.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 KUM60522.1 - 0.19 12.1 8.5 0.38 11.2 8.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain VID27_N PF17748.1 KUM60522.1 - 0.29 11.0 1.6 0.62 9.9 1.6 1.5 1 0 0 1 1 1 0 VID27 N-terminal region NOA36 PF06524.12 KUM60522.1 - 1.9 7.8 8.3 2.9 7.2 8.3 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 KUM60522.1 - 7.4 6.2 14.2 0.088 12.5 6.8 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 KUM60522.1 - 9 4.3 7.8 13 3.8 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cyclin_C_2 PF16899.5 KUM60523.1 - 1.7e-34 118.3 0.0 7.5e-31 106.6 0.0 2.5 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 KUM60523.1 - 2.3e-05 24.2 0.0 4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 KUM60523.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat UQ_con PF00179.26 KUM60524.1 - 3.5e-43 146.6 0.0 4.3e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KUM60524.1 - 5.8e-05 22.8 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 KUM60524.1 - 0.00032 20.4 0.0 0.00048 19.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KUM60524.1 - 0.041 14.2 0.0 0.059 13.7 0.0 1.4 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KUM60524.1 - 0.046 13.6 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF1421 PF07223.11 KUM60524.1 - 0.13 12.1 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain (DUF1421) Glyco_hydro_3 PF00933.21 KUM60526.1 - 0.0016 17.9 0.0 0.0016 17.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Mg_trans_NIPA PF05653.14 KUM60527.1 - 8e-60 202.4 7.8 7.2e-56 189.5 6.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KUM60527.1 - 4.9e-05 23.5 0.5 4.9e-05 23.5 0.5 3.1 3 0 0 3 3 3 1 EamA-like transporter family OPT PF03169.15 KUM60528.1 - 2.8e-186 620.8 56.6 3.2e-186 620.6 56.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_hydro_3_C PF01915.22 KUM60529.1 - 1.7e-54 184.9 0.0 3e-54 184.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KUM60529.1 - 6.7e-50 170.3 0.0 1e-49 169.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KUM60529.1 - 6.1e-22 77.5 1.5 7.8e-22 77.2 0.1 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.13 KUM60529.1 - 0.025 13.7 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain FlaC_arch PF05377.11 KUM60530.1 - 0.0089 16.4 0.7 0.0089 16.4 0.7 2.0 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) TcdB_N PF12918.7 KUM60530.1 - 0.061 13.6 0.9 0.15 12.4 0.9 1.6 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain Rootletin PF15035.6 KUM60530.1 - 0.26 11.3 4.6 0.78 9.7 4.6 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion GAS PF13851.6 KUM60530.1 - 0.44 9.9 6.8 0.2 11.0 3.5 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 KUM60530.1 - 2.5 7.9 4.2 9.4 6.1 4.2 1.9 1 0 0 1 1 1 0 Septum formation initiator Fungal_trans_2 PF11951.8 KUM60533.1 - 1.3e-05 24.2 0.1 1.8e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PIEZO PF15917.5 KUM60533.1 - 0.19 11.1 0.1 0.3 10.5 0.1 1.2 1 0 0 1 1 1 0 Piezo Trypan_PARP PF05887.11 KUM60535.1 - 0.0024 17.9 38.0 0.13 12.2 19.6 2.2 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) VASt PF16016.5 KUM60536.1 - 1.6e-34 119.5 0.0 2.8e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KUM60536.1 - 3.3e-22 78.5 0.0 5.5e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Sugar_tr PF00083.24 KUM60537.1 - 1.1e-66 225.6 19.5 1.3e-66 225.4 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM60537.1 - 3.8e-14 52.4 23.0 3.8e-14 52.4 23.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Asp4 PF16996.5 KUM60537.1 - 0.64 9.9 2.0 2.3 8.1 1.7 2.1 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 FAD_binding_3 PF01494.19 KUM60539.1 - 1.7e-34 119.6 0.0 2.8e-33 115.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KUM60539.1 - 2.4e-09 37.2 0.3 2.6e-05 24.0 0.4 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM60539.1 - 6.2e-09 35.5 0.2 0.00051 19.4 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM60539.1 - 9.6e-08 31.6 0.0 0.00099 18.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KUM60539.1 - 5.7e-06 25.9 0.0 0.0032 16.8 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KUM60539.1 - 2e-05 23.8 0.0 0.065 12.3 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.14 KUM60539.1 - 4e-05 22.7 0.4 0.13 11.1 0.1 3.1 2 1 1 3 3 3 2 Tryptophan halogenase SE PF08491.10 KUM60539.1 - 5.6e-05 22.3 0.0 0.00029 20.0 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase FAD_binding_2 PF00890.24 KUM60539.1 - 5.6e-05 22.4 1.7 0.00086 18.5 0.2 2.2 1 1 1 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KUM60539.1 - 9.9e-05 21.2 0.0 0.011 14.5 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KUM60539.1 - 0.0005 20.2 0.1 0.0011 19.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KUM60539.1 - 0.0043 17.6 0.5 5.2 7.7 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KUM60539.1 - 0.034 13.5 0.1 0.058 12.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KUM60539.1 - 0.043 13.8 0.1 0.69 9.9 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KUM60539.1 - 0.088 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KUM60539.1 - 0.098 11.7 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HPP PF04982.13 KUM60540.1 - 1.9e-36 124.9 7.0 1.9e-36 124.9 7.0 1.8 2 0 0 2 2 2 1 HPP family Na_H_Exchanger PF00999.21 KUM60542.1 - 4e-59 200.3 50.2 5.6e-59 199.8 50.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ADH_N PF08240.12 KUM60543.1 - 4.8e-23 81.1 1.9 9.1e-23 80.2 1.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Aminotran_4 PF01063.19 KUM60543.1 - 3.4e-22 79.4 0.0 5e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV ADH_zinc_N PF00107.26 KUM60543.1 - 3.9e-10 39.8 0.0 2.6e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KUM60543.1 - 0.0058 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain BNR_2 PF13088.6 KUM60543.1 - 0.053 12.8 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 BNR repeat-like domain ABC2_membrane PF01061.24 KUM60544.1 - 1.1e-75 253.7 50.1 7.9e-39 133.2 18.0 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KUM60544.1 - 2.8e-36 125.0 0.0 6.6e-18 65.5 0.0 3.2 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KUM60544.1 - 9e-32 108.8 1.9 3.9e-26 90.8 0.1 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KUM60544.1 - 1.4e-14 54.5 0.0 3.7e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KUM60544.1 - 5.5e-08 32.3 32.1 3.9e-05 22.9 7.9 3.3 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 KUM60544.1 - 1.7e-06 28.5 0.7 0.0033 17.8 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KUM60544.1 - 1.8e-06 27.6 0.1 0.0012 18.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KUM60544.1 - 8.3e-05 22.8 0.1 0.049 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KUM60544.1 - 0.00015 21.7 0.3 0.00053 19.9 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KUM60544.1 - 0.00044 20.8 0.1 0.0044 17.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KUM60544.1 - 0.0038 17.1 0.6 1.5 8.5 0.2 3.1 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 KUM60544.1 - 0.0039 17.6 0.8 0.087 13.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KUM60544.1 - 0.0059 16.5 0.8 2 8.3 0.1 2.7 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 KUM60544.1 - 0.0065 16.2 2.9 0.043 13.6 0.1 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain SMC_N PF02463.19 KUM60544.1 - 0.012 15.1 0.2 0.38 10.2 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KUM60544.1 - 0.039 13.7 0.2 1.6 8.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KUM60544.1 - 0.045 14.2 0.2 8 6.9 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KUM60544.1 - 0.051 12.9 0.0 0.95 8.7 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_23 PF13476.6 KUM60544.1 - 0.051 14.1 0.0 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KUM60544.1 - 0.066 13.2 0.4 2.2 8.3 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KUM60544.1 - 0.092 13.1 0.1 3.3 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KUM60544.1 - 0.18 11.9 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KUM60544.1 - 0.54 10.5 5.7 1.1 9.5 0.2 3.5 3 1 0 3 3 2 0 AAA domain cobW PF02492.19 KUM60544.1 - 1 9.0 5.6 0.68 9.5 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Methyltransf_11 PF08241.12 KUM60546.1 - 1e-12 48.5 0.0 7.2e-12 45.8 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM60546.1 - 1.8e-12 47.4 0.0 2.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM60546.1 - 4.1e-10 40.3 0.0 1.9e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM60546.1 - 1.3e-09 38.6 0.0 9.7e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM60546.1 - 1.1e-07 31.7 0.0 1.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM60546.1 - 0.026 13.9 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 KUM60546.1 - 0.045 12.7 0.0 0.06 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DREV PF05219.12 KUM60546.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Pkinase PF00069.25 KUM60547.1 - 9.1e-41 140.0 0.0 3.7e-40 138.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 KUM60547.1 - 2.4e-40 137.6 0.0 5.1e-40 136.6 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 KUM60547.1 - 1.3e-20 73.8 0.0 3.9e-20 72.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 KUM60547.1 - 0.00053 19.8 0.1 0.34 10.9 0.0 3.2 3 0 0 3 3 3 1 PQQ enzyme repeat Pkinase_fungal PF17667.1 KUM60547.1 - 0.0018 17.1 0.0 0.0068 15.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KUM60547.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_2 PF13360.6 KUM60547.1 - 0.029 14.0 0.3 0.25 10.9 0.2 2.2 1 1 1 2 2 2 0 PQQ-like domain YrbL-PhoP_reg PF10707.9 KUM60547.1 - 0.045 13.3 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cytokin_check_N PF10407.9 KUM60548.1 - 0.00011 22.1 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Fungal_trans_2 PF11951.8 KUM60551.1 - 2.9e-06 26.4 0.2 5.7e-06 25.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3602 PF12223.8 KUM60554.1 - 9.1e-17 61.4 4.0 2e-14 53.9 0.3 2.8 2 2 1 3 3 3 2 Protein of unknown function (DUF3602) ATG16 PF08614.11 KUM60554.1 - 0.00038 20.7 1.9 0.00045 20.5 1.9 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Tim29 PF10171.9 KUM60554.1 - 0.16 11.4 0.0 0.44 10.0 0.0 1.6 1 1 1 2 2 2 0 Translocase of the Inner Mitochondrial membrane 29 ECH_1 PF00378.20 KUM60555.1 - 8.9e-44 149.7 0.0 1.1e-43 149.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KUM60555.1 - 8e-23 81.4 0.2 1.1e-21 77.7 0.2 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pam17 PF08566.10 KUM60556.1 - 9e-66 220.8 0.0 1.2e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 MFS_1 PF07690.16 KUM60558.1 - 8.9e-28 97.2 30.6 8.9e-28 97.2 30.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF485 PF04341.12 KUM60558.1 - 5.2 7.1 6.3 2.1 8.4 2.0 2.6 1 1 1 2 2 2 0 Protein of unknown function, DUF485 Far-17a_AIG1 PF04750.14 KUM60559.1 - 4.2e-64 215.6 9.9 5.4e-64 215.2 9.9 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Fungal_trans_2 PF11951.8 KUM60560.1 - 6.9e-51 173.2 0.6 1.4e-50 172.2 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60560.1 - 1.7e-09 37.6 8.2 3e-09 36.8 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_76 PF03663.14 KUM60561.1 - 8.5e-140 466.4 21.9 9.9e-140 466.2 21.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cloacin_immun PF03513.14 KUM60561.1 - 0.0022 18.3 0.0 0.0058 16.9 0.0 1.6 1 0 0 1 1 1 1 Cloacin immunity protein Cpn60_TCP1 PF00118.24 KUM60562.1 - 5.8e-143 477.1 12.3 6.6e-143 476.9 12.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 KUM60562.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Pro_isomerase PF00160.21 KUM60563.1 - 2.6e-49 167.5 0.1 5.1e-49 166.6 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KUM60563.1 - 2.1e-12 47.3 0.0 0.005 17.7 0.0 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KUM60563.1 - 0.0065 15.5 0.1 0.18 10.7 0.0 2.5 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KUM60563.1 - 0.033 14.5 0.0 5.9 7.3 0.0 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4381 PF14316.6 KUM60564.1 - 0.0083 16.4 0.6 0.02 15.1 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DUF3619 PF12279.8 KUM60564.1 - 0.028 14.8 0.1 0.062 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Synaptobrevin PF00957.21 KUM60564.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Synaptobrevin TMCO5 PF14992.6 KUM60564.1 - 0.34 10.4 0.0 0.43 10.1 0.0 1.1 1 0 0 1 1 1 0 TMCO5 family TMEM154 PF15102.6 KUM60564.1 - 1.3 8.9 2.9 1.1 9.1 0.2 2.2 1 1 0 2 2 2 0 TMEM154 protein family LapA_dom PF06305.11 KUM60564.1 - 1.8 8.4 4.3 1.6 8.6 0.3 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Fungal_trans_2 PF11951.8 KUM60565.1 - 3.7e-14 52.4 0.9 6.8e-14 51.5 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60565.1 - 0.0051 16.9 5.7 0.0084 16.2 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM60565.1 - 0.013 14.5 1.5 0.025 13.6 1.5 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain F_bP_aldolase PF01116.20 KUM60566.1 - 3.9e-72 243.1 0.5 4.6e-72 242.9 0.5 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Amidohydro_1 PF01979.20 KUM60566.1 - 0.0084 15.5 0.4 2.7 7.2 0.0 2.8 1 1 1 3 3 3 2 Amidohydrolase family CobS PF02654.15 KUM60566.1 - 0.18 12.0 0.2 0.34 11.1 0.0 1.6 2 0 0 2 2 2 0 Cobalamin-5-phosphate synthase adh_short_C2 PF13561.6 KUM60567.1 - 8.8e-52 176.0 0.1 1.2e-51 175.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM60567.1 - 7e-41 139.8 0.6 9.6e-41 139.4 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM60567.1 - 2.3e-08 34.1 0.4 3.6e-08 33.5 0.4 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KUM60568.1 - 1.4e-52 178.6 0.3 1.7e-52 178.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM60568.1 - 5.8e-46 156.4 1.6 7.6e-46 156.0 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM60568.1 - 1.7e-06 28.1 0.4 2.7e-06 27.4 0.4 1.3 1 1 0 1 1 1 1 KR domain MFS_1 PF07690.16 KUM60569.1 - 2e-41 142.1 43.1 3.2e-40 138.1 42.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM60569.1 - 2.7e-15 55.9 24.5 3.7e-15 55.4 24.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM60569.1 - 5.5e-12 45.3 9.8 5.5e-12 45.3 9.8 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter Polyoma_lg_T_C PF06431.11 KUM60570.1 - 0.11 11.4 0.2 0.17 10.7 0.2 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Na_H_Exchanger PF00999.21 KUM60571.1 - 2.4e-30 105.6 37.8 5.2e-25 88.0 27.0 3.0 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family Fst_toxin PF13955.6 KUM60571.1 - 4.9 7.2 8.5 0.62 10.0 0.1 3.3 3 0 0 3 3 3 0 Toxin Fst, type I toxin-antitoxin system PigN PF04987.14 KUM60572.1 - 9.8e-165 548.8 35.3 9.8e-165 548.8 35.3 1.5 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Sulfatase PF00884.23 KUM60572.1 - 2.7e-10 40.1 0.6 5.3e-10 39.2 0.2 1.7 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KUM60572.1 - 3e-08 33.6 5.9 9.6e-07 28.7 5.8 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KUM60572.1 - 0.00064 19.1 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Fungal_trans PF04082.18 KUM60573.1 - 4.9e-34 117.6 0.0 3.4e-33 114.8 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60573.1 - 0.033 14.3 4.3 0.056 13.6 4.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CDK2AP PF09806.9 KUM60573.1 - 2.9 7.9 6.4 7.9 6.5 4.4 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Ferric_reduct PF01794.19 KUM60574.1 - 9.7e-22 77.4 15.9 9.7e-22 77.4 15.9 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KUM60574.1 - 1.8e-13 50.5 0.0 4.9e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KUM60574.1 - 4.3e-11 43.2 0.0 7e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.6 KUM60574.1 - 0.00052 20.5 10.2 0.051 14.1 2.1 3.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4405) PALP PF00291.25 KUM60575.1 - 1.7e-32 113.0 0.0 3.1e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 KUM60575.1 - 3.5e-05 24.3 0.0 0.00013 22.4 0.0 2.0 1 0 0 1 1 1 1 Rhodanese-like domain Cys_Met_Meta_PP PF01053.20 KUM60576.1 - 1.1e-141 471.9 0.0 1.2e-141 471.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 KUM60576.1 - 8e-05 21.3 0.0 0.00043 18.9 0.0 1.9 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 KUM60576.1 - 0.00026 20.0 0.0 0.00046 19.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KUM60576.1 - 0.0045 16.3 0.1 0.013 14.9 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KUM60576.1 - 0.017 14.4 0.0 0.054 12.8 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase AAA PF00004.29 KUM60578.1 - 8.4e-37 126.5 0.0 1.7e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KUM60578.1 - 1e-08 34.8 0.0 2.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KUM60578.1 - 2.7e-05 24.6 0.2 0.00095 19.6 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KUM60578.1 - 3.3e-05 23.7 0.0 7.5e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KUM60578.1 - 5.1e-05 23.3 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KUM60578.1 - 8e-05 22.6 0.2 0.00097 19.2 0.2 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KUM60578.1 - 8.7e-05 23.1 0.0 0.001 19.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KUM60578.1 - 0.00015 22.0 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KUM60578.1 - 0.00048 20.3 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KUM60578.1 - 0.00053 20.3 0.8 0.012 15.9 0.1 2.6 2 1 1 3 3 2 1 AAA domain Mg_chelatase PF01078.21 KUM60578.1 - 0.0008 18.8 0.1 0.0015 18.0 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KUM60578.1 - 0.0011 19.3 0.0 0.0034 17.7 0.0 1.9 1 1 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 KUM60578.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein TniB PF05621.11 KUM60578.1 - 0.0018 17.7 0.0 1.7 8.0 0.0 2.5 1 1 1 2 2 2 2 Bacterial TniB protein AAA_25 PF13481.6 KUM60578.1 - 0.0028 17.2 0.2 0.051 13.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KUM60578.1 - 0.006 16.5 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 KUM60578.1 - 0.0071 16.6 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KUM60578.1 - 0.01 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KUM60578.1 - 0.025 14.7 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 KUM60578.1 - 0.029 14.3 0.1 0.08 12.9 0.1 1.6 1 1 1 2 2 2 0 Rad17 P-loop domain Sigma54_activat PF00158.26 KUM60578.1 - 0.034 13.8 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 KUM60578.1 - 0.04 14.4 0.0 0.12 12.9 0.0 1.9 2 1 0 2 2 1 0 ABC transporter ATPase_2 PF01637.18 KUM60578.1 - 0.043 13.7 0.0 0.2 11.6 0.0 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KUM60578.1 - 0.045 12.8 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CPT PF07931.12 KUM60578.1 - 0.05 13.5 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein AAA_7 PF12775.7 KUM60578.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KUM60578.1 - 0.065 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 KUM60578.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KUM60578.1 - 0.13 11.5 0.0 0.55 9.5 0.0 1.9 1 1 1 2 2 2 0 KaiC TIP49 PF06068.13 KUM60578.1 - 0.19 10.9 0.1 0.5 9.5 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain Csm1 PF12539.8 KUM60579.1 - 2.8e-30 104.8 0.1 4.9e-30 104.0 0.1 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Vps5 PF09325.10 KUM60579.1 - 0.015 14.8 4.3 0.039 13.5 4.3 1.7 1 0 0 1 1 1 0 Vps5 C terminal like IFT57 PF10498.9 KUM60579.1 - 0.092 11.7 11.9 0.056 12.4 3.1 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF3138 PF11336.8 KUM60579.1 - 0.12 11.0 5.8 0.21 10.2 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Taxilin PF09728.9 KUM60579.1 - 0.15 11.2 12.4 0.28 10.3 12.4 1.4 1 0 0 1 1 1 0 Myosin-like coiled-coil protein GAS PF13851.6 KUM60579.1 - 0.49 9.7 13.5 0.67 9.3 11.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding COG2 PF06148.11 KUM60579.1 - 0.57 10.3 5.7 2.8 8.0 5.6 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 USP8_interact PF08941.10 KUM60579.1 - 0.71 9.7 3.9 0.2 11.5 0.2 1.9 2 0 0 2 2 2 0 USP8 interacting Spc7 PF08317.11 KUM60579.1 - 1.4 7.8 15.7 5.3 5.8 15.7 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 KUM60579.1 - 2.6 8.1 5.7 4.9 7.2 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CREPT PF16566.5 KUM60579.1 - 2.6 8.2 10.3 8.6 6.5 9.2 2.3 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Baculo_PEP_C PF04513.12 KUM60579.1 - 3.9 7.5 8.2 4.1 7.4 6.3 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.9 KUM60579.1 - 8 5.5 11.6 17 4.4 11.6 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 KUM60579.1 - 8.8 5.5 5.5 15 4.7 5.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein RR_TM4-6 PF06459.12 KUM60580.1 - 0.9 9.3 5.3 0.55 10.0 2.9 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DIT1_PvcA PF05141.12 KUM60581.1 - 6e-86 288.3 0.0 8.7e-86 287.8 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein PreAtp-grasp PF18604.1 KUM60581.1 - 0.052 13.2 0.1 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 Pre ATP-grasp domain DJ-1_PfpI PF01965.24 KUM60582.1 - 7.9e-07 29.0 0.0 2.1e-05 24.4 0.0 2.4 1 1 0 1 1 1 1 DJ-1/PfpI family MTP18 PF10558.9 KUM60583.1 - 1.2e-81 272.8 1.0 1.6e-81 272.3 0.2 1.5 2 0 0 2 2 2 1 Mitochondrial 18 KDa protein (MTP18) ACPS PF01648.20 KUM60584.1 - 4.6e-13 49.3 0.0 6.3e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 KUM60584.1 - 0.0096 16.0 0.2 5.3 7.2 0.0 2.5 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase N-terminal domain Vesiculo_matrix PF06326.12 KUM60584.1 - 0.25 11.1 0.0 0.34 10.7 0.0 1.1 1 0 0 1 1 1 0 Vesiculovirus matrix protein ATP19 PF11022.8 KUM60585.1 - 6.8e-28 96.8 0.1 8.3e-28 96.6 0.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit K FKBP_C PF00254.28 KUM60586.1 - 9.5e-24 83.5 0.0 1.4e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PHP PF02811.19 KUM60587.1 - 5.6e-17 62.5 0.0 2e-16 60.7 0.0 1.8 1 1 0 1 1 1 1 PHP domain COesterase PF00135.28 KUM60589.1 - 1.5e-59 202.3 0.0 2.5e-32 112.4 0.0 3.0 2 1 0 2 2 2 2 Carboxylesterase family DIT1_PvcA PF05141.12 KUM60590.1 - 3.7e-72 243.1 0.0 4.7e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein FAM193_C PF15914.5 KUM60590.1 - 0.038 13.7 0.0 0.099 12.4 0.0 1.7 2 0 0 2 2 2 0 FAM193 family C-terminal MFS_1 PF07690.16 KUM60591.1 - 2.4e-25 89.2 37.3 2.4e-25 89.2 37.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Spb1_C PF07780.12 KUM60592.1 - 5.2e-81 271.3 34.5 5.2e-81 271.3 34.5 3.7 3 2 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 KUM60592.1 - 1.1e-56 191.8 0.0 1.8e-56 191.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KUM60592.1 - 1.9e-49 167.6 8.2 1.9e-49 167.6 8.2 5.2 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 KUM60592.1 - 0.029 14.2 0.0 0.08 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 KUM60594.1 - 6.4e-07 29.4 6.3 1.8e-06 28.0 6.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM60594.1 - 5.1e-05 22.4 0.1 5.1e-05 22.4 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain EF-hand_4 PF12763.7 KUM60595.1 - 0.00023 21.1 0.1 0.00043 20.2 0.1 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand HATPase_c_3 PF13589.6 KUM60595.1 - 0.085 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fungal_trans PF04082.18 KUM60596.1 - 1.6e-20 73.2 2.4 2.9e-20 72.4 2.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KUM60596.1 - 1.7e-06 28.2 16.5 0.00077 19.8 3.0 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KUM60596.1 - 1.8e-06 28.0 8.9 1.8e-06 28.0 8.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KUM60596.1 - 2.8e-06 27.5 5.2 2.8e-06 27.5 5.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KUM60596.1 - 0.0006 20.4 23.7 0.0087 16.8 2.4 3.5 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 KUM60596.1 - 0.0032 17.9 5.0 0.044 14.2 0.3 2.7 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KUM60596.1 - 0.0053 17.1 0.4 0.026 14.9 0.4 2.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KUM60596.1 - 0.043 14.1 7.5 1.9 8.8 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KUM60596.1 - 0.13 13.0 2.4 1.6 9.4 2.0 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 KUM60596.1 - 3.4 7.4 6.7 1.4 8.6 1.3 2.6 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KUM60596.1 - 4.1 7.8 6.3 2.2 8.7 0.4 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Ras PF00071.22 KUM60597.1 - 1.5e-52 177.5 0.5 3.2e-38 130.9 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KUM60597.1 - 4.7e-30 104.3 0.2 1.5e-29 102.6 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM60597.1 - 1.4e-09 37.7 0.3 1.9e-07 30.7 0.1 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KUM60597.1 - 1.1e-06 28.7 0.0 2.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KUM60597.1 - 0.0004 20.3 0.5 0.0066 16.4 0.1 2.5 2 1 1 3 3 3 1 RsgA GTPase Gtr1_RagA PF04670.12 KUM60597.1 - 0.00044 19.7 0.0 0.00082 18.8 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KUM60597.1 - 0.001 18.7 0.8 0.76 9.3 0.1 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KUM60597.1 - 0.0015 18.2 0.1 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KUM60597.1 - 0.0053 16.5 0.6 0.21 11.3 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KUM60597.1 - 0.014 15.8 0.1 0.023 15.1 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KUM60597.1 - 0.022 14.7 0.0 0.047 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KUM60597.1 - 0.022 14.5 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KUM60597.1 - 0.025 14.8 0.0 0.038 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KUM60597.1 - 0.043 13.2 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 KUM60597.1 - 0.047 13.2 0.1 0.08 12.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 KUM60597.1 - 0.063 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Septin NTPase_1 PF03266.15 KUM60597.1 - 0.079 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 KUM60597.1 - 0.11 11.7 0.2 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain Ecotin PF03974.13 KUM60597.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Ecotin NACHT PF05729.12 KUM60597.1 - 0.12 12.2 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KUM60597.1 - 0.19 11.6 0.9 0.23 11.3 0.1 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea EamA PF00892.20 KUM60598.1 - 5.3e-10 39.6 38.2 1.8e-06 28.2 4.5 3.1 3 0 0 3 3 3 3 EamA-like transporter family DUF3955 PF13127.6 KUM60598.1 - 6.7e-07 29.0 3.0 7e-07 29.0 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3955) UAA PF08449.11 KUM60598.1 - 1.3e-05 24.6 9.9 2.2e-05 23.8 9.9 1.3 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 KUM60598.1 - 0.0002 20.7 0.1 0.0002 20.7 0.1 2.1 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 KUM60598.1 - 0.00043 19.9 4.3 0.00043 19.9 4.3 2.1 2 1 0 2 2 2 1 Solute carrier family 35 IDO PF01231.18 KUM60599.1 - 2.3e-31 109.1 0.1 1.3e-30 106.6 0.0 1.9 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase Cyt-b5 PF00173.28 KUM60599.1 - 6.5e-16 58.2 0.0 1.4e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain LMP PF04778.12 KUM60599.1 - 0.19 11.6 0.3 0.41 10.6 0.3 1.5 1 0 0 1 1 1 0 LMP repeated region p450 PF00067.22 KUM60600.1 - 1.3e-52 179.1 0.0 1.4e-52 179.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MARVEL PF01284.23 KUM60601.1 - 1.3 9.0 13.7 0.14 12.1 1.3 3.2 2 1 0 2 2 2 0 Membrane-associating domain Trp_DMAT PF11991.8 KUM60602.1 - 1.6e-10 40.9 0.1 4.2e-10 39.6 0.1 1.6 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase GGN PF15685.5 KUM60602.1 - 0.094 11.8 0.6 0.15 11.1 0.0 1.5 2 0 0 2 2 2 0 Gametogenetin cIII PF08134.11 KUM60603.1 - 0.075 12.8 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 cIII protein family DUF4366 PF14283.6 KUM60605.1 - 0.05 13.7 4.9 0.084 12.9 4.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) AJAP1_PANP_C PF15298.6 KUM60605.1 - 0.12 12.6 2.0 0.16 12.2 2.0 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus CDC27 PF09507.10 KUM60605.1 - 0.76 9.1 13.3 0.95 8.8 13.3 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Kei1 PF08552.11 KUM60605.1 - 10 6.0 7.5 49 3.7 7.5 1.8 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Peptidase_S76 PF13611.6 KUM60606.1 - 0.02 15.2 0.0 0.076 13.3 0.0 2.0 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 Big_3_3 PF13750.6 KUM60606.1 - 0.082 12.6 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) YEATS PF03366.16 KUM60607.1 - 2.1e-19 69.3 0.2 3.8e-19 68.4 0.2 1.4 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KUM60607.1 - 3.2e-05 24.0 0.2 6.1e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Ran_BP1 PF00638.18 KUM60608.1 - 4.6e-45 152.8 0.7 5.3e-45 152.6 0.7 1.0 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KUM60608.1 - 8.1e-06 25.7 0.6 5.2e-05 23.1 0.6 1.9 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 KUM60608.1 - 0.00055 20.2 0.0 0.00065 20.0 0.0 1.1 1 0 0 1 1 1 1 VID27 PH-like domain Lig_C PF18330.1 KUM60608.1 - 0.07 13.1 0.0 0.18 11.8 0.0 1.7 1 1 1 2 2 2 0 Ligase Pab1020 C-terminal region MFS_1 PF07690.16 KUM60612.1 - 1.5e-33 116.2 46.0 1.5e-33 116.2 46.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM60612.1 - 0.00012 21.1 15.7 0.00012 21.1 15.7 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter Otopetrin PF03189.13 KUM60612.1 - 0.012 14.5 2.5 0.023 13.6 2.5 1.4 1 0 0 1 1 1 0 Otopetrin Phage_holin_5_1 PF06946.11 KUM60612.1 - 0.071 13.5 2.7 0.78 10.2 0.8 3.3 2 1 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 PH PF00169.29 KUM60613.1 - 3.9e-27 94.8 0.0 2.6e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 KUM60613.1 - 7.6e-10 39.2 0.2 7.6e-05 23.1 0.0 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KUM60613.1 - 1e-07 32.3 1.3 0.008 16.6 0.2 3.3 2 2 0 2 2 2 2 Pleckstrin homology domain Glyco_transf_15 PF01793.16 KUM60614.1 - 1.6e-95 320.1 11.5 6.6e-95 318.1 11.5 1.8 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DOT1 PF08123.13 KUM60615.1 - 5.1e-77 258.0 0.0 6.9e-77 257.6 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 ATG16 PF08614.11 KUM60616.1 - 8.4e-59 199.2 20.3 9.5e-59 199.0 20.3 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CCDC144C PF14915.6 KUM60616.1 - 0.0025 17.0 10.1 0.0043 16.2 10.1 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region APG6_N PF17675.1 KUM60616.1 - 0.0026 18.3 10.3 0.0026 18.3 10.3 2.1 2 0 0 2 2 2 1 Apg6 coiled-coil region Golgin_A5 PF09787.9 KUM60616.1 - 0.0029 17.1 7.6 0.0033 16.9 7.6 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 UPF0242 PF06785.11 KUM60616.1 - 0.016 15.3 14.4 0.052 13.7 3.4 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Sec2p PF06428.11 KUM60616.1 - 0.082 12.9 14.5 0.088 12.8 12.0 2.1 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fez1 PF06818.15 KUM60616.1 - 0.091 13.2 13.4 0.62 10.5 4.7 2.3 1 1 1 2 2 2 0 Fez1 MscS_porin PF12795.7 KUM60616.1 - 0.23 10.9 28.8 0.91 9.0 18.5 2.9 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain HAUS-augmin3 PF14932.6 KUM60616.1 - 0.33 10.5 12.7 0.03 13.9 7.6 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 KUM60616.1 - 0.34 9.7 14.5 0.46 9.3 12.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein FAM76 PF16046.5 KUM60616.1 - 0.4 10.0 6.3 0.51 9.6 6.3 1.2 1 0 0 1 1 1 0 FAM76 protein Nup54 PF13874.6 KUM60616.1 - 0.42 10.7 13.7 0.061 13.4 4.6 2.6 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 FlaC_arch PF05377.11 KUM60616.1 - 0.6 10.5 4.6 4.7 7.7 0.5 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) FapA PF03961.13 KUM60616.1 - 0.65 8.5 4.4 0.95 8.0 4.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A BRE1 PF08647.11 KUM60616.1 - 1.2 9.3 15.7 0.38 10.8 11.0 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 KUM60616.1 - 1.6 8.8 6.6 6.8 6.7 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 KUM60616.1 - 1.6 9.0 17.1 0.99 9.7 5.7 3.7 2 1 2 4 4 4 0 ABC transporter C-terminal domain DUF2203 PF09969.9 KUM60616.1 - 2.2 9.0 8.8 0.24 12.1 2.5 2.3 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) YabA PF06156.13 KUM60616.1 - 3.3 8.4 12.2 3.5 8.3 2.3 2.5 2 1 1 3 3 2 0 Initiation control protein YabA DUF4407 PF14362.6 KUM60616.1 - 4.1 6.7 20.3 32 3.8 20.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) XhlA PF10779.9 KUM60616.1 - 5.3 7.3 6.1 25 5.2 1.9 2.6 2 0 0 2 2 2 0 Haemolysin XhlA DUF4201 PF13870.6 KUM60616.1 - 5.5 6.7 17.3 3.9 7.2 14.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Sterol_MT_C PF08498.10 KUM60618.1 - 3.1e-26 91.5 0.0 5.5e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KUM60618.1 - 4.7e-22 78.5 0.0 9.6e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM60618.1 - 5.3e-19 68.7 0.0 1.1e-18 67.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM60618.1 - 3.9e-18 65.7 0.0 6.4e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM60618.1 - 5.1e-10 40.0 0.0 1.1e-09 39.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM60618.1 - 5.2e-10 39.1 0.0 8.8e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KUM60618.1 - 8.9e-10 38.6 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KUM60618.1 - 4.6e-07 29.4 0.0 6.4e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KUM60618.1 - 0.0025 17.6 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.16 KUM60618.1 - 0.0033 16.0 0.0 0.0051 15.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 KUM60618.1 - 0.0093 15.6 0.0 0.024 14.2 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW NodS PF05401.11 KUM60618.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) PrmA PF06325.13 KUM60618.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KUM60618.1 - 0.026 14.1 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 KUM60618.1 - 0.048 13.7 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DRE2_N PF16803.5 KUM60618.1 - 0.066 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus RrnaAD PF00398.20 KUM60618.1 - 0.078 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.15 KUM60618.1 - 0.1 12.4 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 Hypothetical methyltransferase TehB PF03848.14 KUM60618.1 - 0.14 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Glyco_hydro_17 PF00332.18 KUM60621.1 - 3.4e-09 36.7 5.7 3.3e-06 26.9 0.9 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Rick_17kDa_Anti PF05433.15 KUM60621.1 - 0.016 15.1 0.5 0.016 15.1 0.5 3.2 2 1 0 2 2 2 0 Glycine zipper 2TM domain ISPD_C PF18706.1 KUM60621.1 - 0.034 13.8 0.1 0.053 13.2 0.1 1.2 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain DUF1269 PF06897.12 KUM60621.1 - 0.32 11.3 0.1 0.32 11.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) DUF4336 PF14234.6 KUM60622.1 - 1.4e-16 60.6 0.0 6e-12 45.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) Nse4_C PF08743.10 KUM60623.1 - 5.4e-33 113.1 0.0 3.1e-32 110.7 0.0 2.4 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KUM60623.1 - 3.9e-16 58.9 0.1 1.1e-15 57.5 0.1 1.8 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE OGFr_III PF04680.13 KUM60623.1 - 7.6 7.3 7.6 0.95 10.2 2.2 2.5 2 0 0 2 2 2 0 Opioid growth factor receptor repeat zf-C3H1 PF10650.9 KUM60624.1 - 1.7e-13 50.0 0.5 2.6e-13 49.4 0.5 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain DHHC PF01529.20 KUM60625.1 - 1.8e-24 86.4 10.3 1.8e-24 86.4 10.3 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Isy1 PF06246.12 KUM60626.1 - 7.7e-84 281.2 0.4 8.8e-84 281.0 0.4 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Myosin_head PF00063.21 KUM60627.1 - 7.1e-263 873.8 0.0 1.9e-262 872.5 0.0 1.8 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KUM60627.1 - 3.7e-18 64.8 274.9 6.5e-12 44.1 191.4 5.8 1 1 1 2 2 2 2 Myosin tail Myosin_N PF02736.19 KUM60627.1 - 5.1e-08 32.6 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF4525 PF15027.6 KUM60627.1 - 0.017 14.8 2.4 0.028 14.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) AAA_22 PF13401.6 KUM60627.1 - 0.15 12.4 0.0 0.15 12.4 0.0 4.7 4 1 0 4 4 4 0 AAA domain MMR_HSR1 PF01926.23 KUM60629.1 - 3.7e-15 56.0 0.0 7.5e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KUM60629.1 - 1.3e-06 28.4 0.2 2.8e-06 27.4 0.2 1.5 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KUM60629.1 - 2.6e-06 27.1 0.1 3.7e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 KUM60629.1 - 3e-05 23.5 0.0 4.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 KUM60629.1 - 0.00057 19.2 0.0 0.00096 18.5 0.0 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 KUM60629.1 - 0.0083 15.7 0.0 0.024 14.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KUM60629.1 - 0.013 16.0 0.1 0.028 15.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KUM60629.1 - 0.027 14.8 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 KUM60629.1 - 0.03 13.8 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KUM60629.1 - 0.05 13.0 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Dynamin_N PF00350.23 KUM60629.1 - 0.056 13.5 0.1 0.65 10.0 0.1 2.2 1 1 0 2 2 2 0 Dynamin family Roc PF08477.13 KUM60629.1 - 0.073 13.3 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM60629.1 - 0.14 11.6 0.0 0.6 9.5 0.0 1.7 1 1 0 2 2 2 0 ADP-ribosylation factor family PI3Ka PF00613.20 KUM60630.1 - 1.2e-57 194.3 0.4 2e-57 193.6 0.4 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KUM60630.1 - 1.5e-43 149.4 0.0 1.4e-30 106.9 0.0 2.7 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KUM60630.1 - 9.8e-30 103.3 0.0 1.6e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 zf-H2C2_2 PF13465.6 KUM60631.1 - 0.00029 21.1 1.0 0.00029 21.1 1.0 2.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KUM60631.1 - 0.00059 20.2 8.4 0.0073 16.7 1.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM60631.1 - 0.0033 18.1 7.7 0.032 15.1 1.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 KUM60631.1 - 0.024 14.9 1.2 0.04 14.2 1.2 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 KUM60631.1 - 0.031 14.9 3.0 0.044 14.4 0.3 2.1 2 0 0 2 2 2 0 FOXP coiled-coil domain Septin PF00735.18 KUM60635.1 - 1.3e-120 402.0 0.1 2.2e-120 401.2 0.1 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KUM60635.1 - 1.3e-07 31.6 0.6 2.6e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KUM60635.1 - 8.8e-07 28.7 0.7 0.0002 20.9 0.0 2.7 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KUM60635.1 - 1.2e-05 25.3 1.9 0.00038 20.4 0.4 2.8 2 1 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KUM60635.1 - 0.00018 20.9 0.8 0.00047 19.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.27 KUM60635.1 - 0.0003 21.3 2.6 0.027 15.0 0.0 3.0 2 1 0 2 2 2 1 ABC transporter Roc PF08477.13 KUM60635.1 - 0.00074 19.7 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KUM60635.1 - 0.0017 18.0 0.1 0.019 14.5 0.0 2.5 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 KUM60635.1 - 0.0019 18.6 0.1 0.0057 17.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KUM60635.1 - 0.0035 17.6 0.8 0.013 15.8 0.0 2.3 2 2 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 KUM60635.1 - 0.009 15.8 0.6 2 8.1 0.1 3.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 KUM60635.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KUM60635.1 - 0.031 14.0 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KUM60635.1 - 0.058 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 KUM60635.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KUM60635.1 - 0.091 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KUM60635.1 - 0.16 12.4 0.2 0.67 10.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Exonuc_VII_L PF02601.15 KUM60635.1 - 0.52 9.8 4.2 0.95 9.0 4.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit IIGP PF05049.13 KUM60635.1 - 0.57 9.2 4.1 0.28 10.2 0.2 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 KUM60635.1 - 0.86 9.6 7.9 0.2 11.7 0.3 3.3 3 2 0 3 3 3 0 Dynamin family TSNAXIP1_N PF15739.5 KUM60635.1 - 1 9.8 11.1 5.7 7.4 0.0 2.9 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus DUF3987 PF13148.6 KUM60635.1 - 6.9 5.6 8.5 1.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) MASE1 PF05231.14 KUM60637.1 - 0.11 11.7 14.9 0.018 14.2 4.2 2.1 2 0 0 2 2 2 0 MASE1 Methyltransf_2 PF00891.18 KUM60638.1 - 2.4e-21 76.0 0.0 3.6e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KUM60638.1 - 0.00078 19.4 0.0 0.0021 18.0 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 KUM60638.1 - 0.0083 16.1 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.20 KUM60638.1 - 0.19 12.1 0.0 0.8 10.1 0.0 2.0 3 0 0 3 3 3 0 Transcriptional regulator PfkB PF00294.24 KUM60639.1 - 1.5e-13 50.7 0.0 2.3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TPK_catalytic PF04263.16 KUM60640.1 - 1.3e-32 112.3 0.1 1.8e-31 108.7 0.0 2.3 2 1 0 2 2 2 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KUM60640.1 - 8.8e-21 73.4 0.0 1.6e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Ribosomal_60s PF00428.19 KUM60640.1 - 0.028 15.0 1.1 0.028 15.0 1.1 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein CBP_CCPA PF17040.5 KUM60640.1 - 0.03 14.9 0.5 0.09 13.4 0.1 2.1 2 0 0 2 2 2 0 Cellulose-complementing protein A Med21 PF11221.8 KUM60640.1 - 0.8 10.0 7.9 31 4.8 7.9 2.4 1 1 0 1 1 1 0 Subunit 21 of Mediator complex CHCH PF06747.13 KUM60641.1 - 3e-08 33.6 4.1 5e-08 32.9 4.1 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KUM60641.1 - 0.0031 17.9 1.2 0.0065 16.9 1.2 1.6 1 0 0 1 1 1 1 GCK domain POB3_N PF17292.2 KUM60642.1 - 1.6e-30 105.4 0.0 5.7e-29 100.4 0.0 2.8 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 KUM60642.1 - 6.5e-29 99.7 2.4 1.3e-28 98.7 0.0 2.9 5 0 0 5 5 5 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KUM60642.1 - 7.4e-27 93.6 0.1 9.9e-26 90.0 0.0 2.6 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Rax2 PF12768.7 KUM60643.1 - 1.6e-71 240.2 0.6 1.4e-69 233.8 0.0 3.8 5 0 0 5 5 5 1 Cortical protein marker for cell polarity DUF5122 PF17164.4 KUM60643.1 - 1 9.7 14.8 6.2 7.2 0.2 6.1 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller Fungal_trans_2 PF11951.8 KUM60644.1 - 2.8e-06 26.4 1.0 1.4e-05 24.1 1.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain SH3_3 PF08239.11 KUM60646.1 - 0.00058 20.1 0.1 0.001 19.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain UPF0121 PF03661.13 KUM60647.1 - 1.2e-31 109.9 9.3 1.6e-31 109.5 9.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Mito_carr PF00153.27 KUM60648.1 - 2.4e-62 206.9 1.7 1.2e-19 70.1 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein SWIRM-assoc_2 PF16496.5 KUM60649.1 - 0.021 13.7 2.0 0.028 13.3 2.0 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Rho_N PF07498.12 KUM60649.1 - 0.031 14.2 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain PALP PF00291.25 KUM60650.1 - 4.9e-07 29.5 0.0 5.7e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PLU-1 PF08429.11 KUM60651.1 - 3e-109 365.3 17.9 3.8e-105 351.8 16.7 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 KUM60651.1 - 6e-43 145.9 0.1 1.5e-42 144.6 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 KUM60651.1 - 2.1e-21 76.4 0.0 5.8e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KUM60651.1 - 1.2e-17 63.6 1.6 4.1e-17 61.8 1.6 2.1 2 0 0 2 2 2 1 jmjN domain PHD PF00628.29 KUM60651.1 - 1.9e-17 62.9 30.9 1.5e-09 37.6 7.8 3.6 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.16 KUM60651.1 - 3.8e-13 49.6 8.9 1.4e-12 47.8 8.9 2.1 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.6 KUM60651.1 - 0.00022 20.9 1.8 0.00022 20.9 1.8 2.9 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 KUM60651.1 - 0.0032 17.4 2.8 0.0032 17.4 2.8 3.2 2 1 1 3 3 3 1 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KUM60651.1 - 0.0038 16.7 2.6 0.0038 16.7 2.6 2.8 3 0 0 3 3 3 1 PHD-finger Desulfoferrodox PF01880.18 KUM60651.1 - 0.047 14.3 0.3 0.11 13.1 0.3 1.6 1 0 0 1 1 1 0 Desulfoferrodoxin PHD_4 PF16866.5 KUM60651.1 - 5.6 7.1 22.0 1.2 9.3 5.1 3.2 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.22 KUM60651.1 - 6 6.8 24.5 0.24 11.3 0.5 3.6 3 0 0 3 3 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TGT PF01702.18 KUM60652.1 - 3.4e-67 227.1 0.0 4.2e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MTHFR PF02219.17 KUM60653.1 - 9.4e-95 317.2 0.0 1.3e-94 316.7 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase GIY-YIG PF01541.24 KUM60654.1 - 5.8e-13 48.9 0.0 2.2e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 GIY-YIG catalytic domain FANCL_C PF11793.8 KUM60654.1 - 5.2e-05 23.3 2.6 8.9e-05 22.6 2.6 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 KUM60654.1 - 0.0091 16.2 0.7 0.019 15.2 0.7 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 KUM60654.1 - 0.012 15.5 3.3 0.012 15.5 3.3 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FYDLN_acid PF09538.10 KUM60654.1 - 0.099 13.3 0.2 0.31 11.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-RING_2 PF13639.6 KUM60654.1 - 0.37 11.2 6.0 0.77 10.1 6.0 1.6 1 0 0 1 1 1 0 Ring finger domain Thymidylate_kin PF02223.17 KUM60655.1 - 2.4e-48 164.3 0.0 2.8e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 KUM60655.1 - 0.0006 19.3 0.1 0.0015 18.0 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 KUM60655.1 - 0.025 15.0 0.0 0.041 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KUM60655.1 - 0.11 11.8 0.1 1.1 8.5 0.0 2.2 2 1 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 KUM60655.1 - 0.12 12.9 0.0 0.35 11.4 0.0 1.8 1 1 1 2 2 2 0 AAA domain NMT1 PF09084.11 KUM60656.1 - 0.00027 21.0 0.1 0.00085 19.3 0.0 1.9 2 1 0 2 2 2 1 NMT1/THI5 like Phosphonate-bd PF12974.7 KUM60656.1 - 0.0037 16.9 0.1 0.013 15.1 0.1 1.9 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 KUM60656.1 - 0.16 11.3 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family Glyco_hydro_18 PF00704.28 KUM60657.1 - 1.4e-25 90.7 3.8 6.1e-25 88.6 3.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 SOG2 PF10428.9 KUM60657.1 - 0.015 14.6 23.4 0.019 14.2 23.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CDC27 PF09507.10 KUM60657.1 - 1.7 8.0 21.0 2.6 7.4 21.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hamartin PF04388.12 KUM60657.1 - 2.5 6.7 20.5 3.4 6.2 20.5 1.1 1 0 0 1 1 1 0 Hamartin protein DUF966 PF06136.13 KUM60657.1 - 2.8 7.6 14.5 4.2 7.0 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Utp14 PF04615.13 KUM60657.1 - 5.3 5.5 13.4 7.8 4.9 13.4 1.1 1 0 0 1 1 1 0 Utp14 protein GREB1 PF15782.5 KUM60657.1 - 7.6 3.5 13.5 9.8 3.1 13.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer E1-E2_ATPase PF00122.20 KUM60658.1 - 8.9e-35 119.8 5.6 1.9e-22 79.7 0.4 3.6 3 0 0 3 3 3 3 E1-E2 ATPase Hydrolase PF00702.26 KUM60658.1 - 4.4e-18 66.3 0.0 1.3e-17 64.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KUM60658.1 - 1.6e-08 34.1 0.0 3.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KUM60658.1 - 0.0045 16.7 0.1 0.022 14.5 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TRAP_beta PF05753.14 KUM60658.1 - 0.14 11.6 0.0 0.36 10.2 0.0 1.6 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) PQ-loop PF04193.14 KUM60659.1 - 2.6e-20 71.9 3.2 9.7e-13 47.7 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat LMBR1 PF04791.16 KUM60659.1 - 0.00028 20.0 0.0 0.00057 18.9 0.0 1.5 1 1 0 1 1 1 1 LMBR1-like membrane protein Phage_holin_5_2 PF16079.5 KUM60659.1 - 0.065 13.6 4.2 0.12 12.7 0.1 2.6 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V ER_lumen_recept PF00810.18 KUM60659.1 - 0.074 13.9 5.3 0.65 10.8 5.3 2.2 1 1 0 1 1 1 0 ER lumen protein retaining receptor AAA_lid_4 PF17864.1 KUM60660.1 - 0.02 14.7 0.4 0.032 14.0 0.4 1.3 1 0 0 1 1 1 0 RuvB AAA lid domain DUF3623 PF12291.8 KUM60660.1 - 0.14 11.4 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) MFS_1 PF07690.16 KUM60661.1 - 1.4e-38 132.7 30.4 1.4e-38 132.7 30.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily SpoVAB PF13782.6 KUM60661.1 - 0.0032 17.7 0.8 0.0032 17.7 0.8 2.4 3 0 0 3 3 3 1 Stage V sporulation protein AB DUF1820 PF08850.11 KUM60661.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1820) TraL PF07178.11 KUM60661.1 - 1.8 9.1 5.6 1.4 9.5 2.3 2.6 2 0 0 2 2 2 0 TraL protein Glyco_hydro_31 PF01055.26 KUM60662.1 - 2.4e-136 455.4 8.3 3.3e-136 455.0 8.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KUM60662.1 - 7.7e-25 87.0 0.7 5.7e-24 84.2 0.1 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KUM60662.1 - 5.4e-08 33.0 0.5 1.9e-07 31.3 0.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Sugar_tr PF00083.24 KUM60663.1 - 2.4e-42 145.4 24.3 1.3e-41 143.0 24.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM60663.1 - 4.2e-37 127.9 47.9 1.5e-31 109.6 29.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavi_NS4A PF01350.17 KUM60663.1 - 0.3 11.0 2.2 0.43 10.5 0.8 1.9 1 1 1 2 2 2 0 Flavivirus non-structural protein NS4A FANCI_HD2 PF14680.6 KUM60664.1 - 0.056 12.7 0.1 0.068 12.4 0.1 1.1 1 0 0 1 1 1 0 FANCI helical domain 2 HD PF01966.22 KUM60665.1 - 9.3e-05 22.6 0.5 9.3e-05 22.6 0.5 1.7 2 0 0 2 2 2 1 HD domain CN_hydrolase PF00795.22 KUM60666.1 - 1.3e-41 142.6 0.0 1.9e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.18 KUM60667.1 - 2.6e-15 56.2 0.8 3.6e-15 55.7 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_1 PF01979.20 KUM60668.1 - 4.9e-22 78.7 0.0 6.9e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KUM60668.1 - 6.2e-19 68.8 0.0 4.8e-07 29.6 0.1 3.2 3 0 0 3 3 3 3 Amidohydrolase family Urease_alpha PF00449.20 KUM60668.1 - 0.22 11.9 0.4 0.44 10.9 0.4 1.5 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain NDK PF00334.19 KUM60669.1 - 3.7e-53 179.2 0.0 4.8e-53 178.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.9 KUM60670.1 - 3.3e-29 101.1 0.0 5.8e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KUM60670.1 - 0.0016 18.9 0.0 0.002 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) C_Hendra PF16821.5 KUM60670.1 - 0.41 10.5 0.8 0.62 9.9 0.8 1.3 1 0 0 1 1 1 0 C protein from hendra and measles viruses Amidohydro_3 PF07969.11 KUM60672.1 - 3.5e-19 69.6 1.2 1.1e-11 44.9 0.0 3.1 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 KUM60672.1 - 3.8e-14 52.8 0.4 1.3e-11 44.5 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family NACHT_N PF17100.5 KUM60673.1 - 5.9e-39 134.2 0.0 1.4e-38 132.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 KUM60673.1 - 5e-20 71.9 0.0 3.8e-05 24.2 0.0 5.4 5 1 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM60673.1 - 1.8e-19 69.8 0.3 3.1e-07 30.8 0.1 5.8 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM60673.1 - 8e-17 61.1 1.7 1e-06 28.9 0.2 4.4 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM60673.1 - 5.4e-15 54.0 0.6 0.0075 16.7 0.0 7.1 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 KUM60673.1 - 3.1e-13 49.5 0.0 0.0014 18.9 0.1 6.4 7 0 0 7 7 7 3 Ankyrin repeat NACHT PF05729.12 KUM60673.1 - 3.8e-07 30.2 0.0 1.4e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KUM60673.1 - 0.039 14.3 0.0 0.17 12.3 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.14 KUM60673.1 - 0.041 13.1 0.0 2.7 7.2 0.0 2.5 2 0 0 2 2 2 0 KAP family P-loop domain Cas6 PF09559.10 KUM60674.1 - 0.042 13.8 0.7 0.069 13.1 0.7 1.3 1 0 0 1 1 1 0 Cas6 Crispr TPR_MLP1_2 PF07926.12 KUM60674.1 - 3.4 7.7 25.2 2.9 8.0 14.5 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein YgaB PF14182.6 KUM60674.1 - 5.3 7.5 15.3 0.47 10.9 5.0 2.9 1 1 1 2 2 2 0 YgaB-like protein Abhydrolase_6 PF12697.7 KUM60675.1 - 3.7e-13 50.6 1.1 5.3e-13 50.1 1.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM60675.1 - 2.8e-10 40.3 0.1 9.8e-10 38.5 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM60675.1 - 2.8e-07 30.1 0.0 4.2e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Phage_tail_APC PF16778.5 KUM60675.1 - 0.0011 18.8 0.1 0.65 9.9 0.1 2.6 2 0 0 2 2 2 2 Phage tail assembly chaperone protein Thioesterase PF00975.20 KUM60675.1 - 0.016 15.3 0.8 0.048 13.8 0.8 1.9 1 1 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 KUM60675.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.13 KUM60675.1 - 0.09 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_5 PF12695.7 KUM60675.1 - 0.12 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.16 KUM60676.1 - 7.9e-36 123.7 25.7 1.2e-35 123.1 25.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KUM60676.1 - 0.00072 18.0 2.4 0.0053 15.1 0.8 2.4 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF3981 PF13139.6 KUM60676.1 - 0.019 15.4 0.6 0.046 14.1 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3981) FAD_binding_3 PF01494.19 KUM60677.1 - 9.2e-12 44.9 0.1 2.4e-11 43.5 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KUM60677.1 - 1.7e-07 31.2 2.1 4.4e-06 26.5 0.2 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM60677.1 - 3.3e-05 23.3 0.4 0.00054 19.3 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM60677.1 - 3.8e-05 23.8 0.1 8.6e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KUM60677.1 - 0.0029 16.9 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KUM60677.1 - 0.0076 16.3 0.3 0.023 14.7 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KUM60677.1 - 0.028 13.3 1.3 0.13 11.1 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.24 KUM60677.1 - 0.041 13.0 0.0 0.077 12.1 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KUM60677.1 - 0.061 12.0 0.0 0.15 10.8 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Lipase_GDSL_2 PF13472.6 KUM60678.1 - 3.3e-21 76.5 0.4 5e-21 75.9 0.4 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KUM60678.1 - 4e-12 46.5 0.0 5.8e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.16 KUM60679.1 - 3.9e-33 114.8 28.8 3.9e-33 114.8 28.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3445 PF11927.8 KUM60680.1 - 7.5e-60 202.4 0.0 8.9e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Fungal_trans PF04082.18 KUM60681.1 - 3.8e-14 52.4 0.2 6.5e-14 51.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60681.1 - 1.9e-10 40.6 8.3 3.6e-10 39.8 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KUM60682.1 - 2e-34 119.2 0.0 2.2e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Neurochondrin PF05536.11 KUM60682.1 - 0.19 10.0 0.0 0.26 9.6 0.0 1.1 1 0 0 1 1 1 0 Neurochondrin MFS_1 PF07690.16 KUM60683.1 - 2.4e-34 118.8 28.2 2.9e-34 118.6 28.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily NUP PF06516.11 KUM60684.1 - 6.6e-136 452.6 0.3 7.6e-136 452.4 0.3 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) DUF4440 PF14534.6 KUM60685.1 - 5.8e-10 39.5 0.0 6.6e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 KUM60685.1 - 0.067 13.8 0.0 0.083 13.5 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Aldo_ket_red PF00248.21 KUM60686.1 - 4.7e-73 245.9 0.0 5.3e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_Tnp_1 PF01527.20 KUM60686.1 - 0.1 12.9 0.0 4.7 7.6 0.0 3.0 3 0 0 3 3 3 0 Transposase Fungal_trans PF04082.18 KUM60687.1 - 0.0028 16.7 0.2 0.006 15.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60687.1 - 0.1 12.7 14.5 0.25 11.5 14.5 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP70 PF00012.20 KUM60689.1 - 0.0001 20.7 0.0 0.002 16.4 0.0 2.3 2 1 0 2 2 2 2 Hsp70 protein AMP-binding PF00501.28 KUM60690.1 - 2.2e-283 939.1 0.0 8.5e-81 271.7 0.0 4.5 5 0 0 5 5 5 4 AMP-binding enzyme Condensation PF00668.20 KUM60690.1 - 2.5e-117 392.3 0.0 2e-36 125.7 0.0 6.3 5 1 0 5 5 5 5 Condensation domain PP-binding PF00550.25 KUM60690.1 - 6.1e-35 119.4 0.5 5.6e-11 42.6 0.0 4.8 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM60690.1 - 2.1e-08 35.0 0.6 0.62 11.1 0.0 4.9 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain PEP_mutase PF13714.6 KUM60691.1 - 4.3e-41 140.9 0.0 5.1e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KUM60691.1 - 6.3e-22 77.8 0.1 8.8e-22 77.3 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pox_G5 PF04599.12 KUM60692.1 - 0.12 11.4 0.4 0.17 10.9 0.4 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein FAD_binding_4 PF01565.23 KUM60693.1 - 3.6e-31 107.8 6.9 6.6e-31 106.9 6.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KUM60693.1 - 3e-11 43.2 0.1 5.2e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like Aldedh PF00171.22 KUM60694.1 - 8.9e-163 542.1 0.1 1e-162 541.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KUM60694.1 - 0.0098 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Pec_lyase_C PF00544.19 KUM60695.1 - 6.7e-43 146.7 9.3 9.2e-43 146.3 9.3 1.2 1 0 0 1 1 1 1 Pectate lyase DIOX_N PF14226.6 KUM60696.1 - 3.6e-19 69.6 0.0 8e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KUM60696.1 - 7.7e-18 64.8 0.0 1.5e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tautomerase_3 PF14832.6 KUM60697.1 - 9.3e-52 174.9 0.1 1e-51 174.7 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Epimerase PF01370.21 KUM60698.1 - 1e-17 64.5 0.0 1.8e-17 63.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KUM60698.1 - 2.5e-11 43.1 0.0 1.1e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KUM60698.1 - 2e-09 37.3 0.0 5.2e-07 29.4 0.0 2.8 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KUM60698.1 - 7e-08 32.3 0.0 5.9e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KUM60698.1 - 8.8e-08 32.2 0.0 2e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KUM60698.1 - 6.4e-06 25.5 0.0 0.002 17.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KUM60698.1 - 0.00024 20.3 0.0 0.0018 17.5 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KUM60698.1 - 0.00041 19.9 0.1 0.0011 18.4 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KUM60698.1 - 0.067 13.1 0.0 8.5 6.2 0.0 2.3 2 0 0 2 2 2 0 KR domain zf-CCCH PF00642.24 KUM60699.1 - 4e-20 71.2 29.5 2.9e-06 27.1 1.0 5.2 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KUM60699.1 - 1.2e-13 50.6 31.3 0.00012 21.9 2.5 5.2 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 KUM60699.1 - 1.4e-12 48.3 25.4 5.9e-06 26.9 0.8 5.3 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 KUM60699.1 - 2.3e-05 24.1 0.8 2.3e-05 24.1 0.8 4.9 5 0 0 5 5 5 1 CCCH-type zinc finger zf-C3H1 PF10650.9 KUM60699.1 - 0.0049 16.6 6.7 0.64 9.8 0.1 3.8 4 0 0 4 4 4 2 Putative zinc-finger domain zf-CCCH_3 PF15663.5 KUM60699.1 - 1.6 8.9 15.2 2.4 8.4 2.4 3.9 2 1 2 4 4 4 0 Zinc-finger containing family Nab2p_Zf1 PF18260.1 KUM60699.1 - 4.2 7.4 16.0 2.1 8.3 4.6 3.3 3 0 0 3 3 3 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 Aldo_ket_red PF00248.21 KUM60700.1 - 2.5e-62 210.7 0.0 3e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_psq PF05225.16 KUM60700.1 - 0.1 12.4 0.4 84 3.0 0.0 3.9 4 0 0 4 4 4 0 helix-turn-helix, Psq domain Evf PF18270.1 KUM60700.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Virulence factor Evf YCII PF03795.14 KUM60701.1 - 3.1e-07 30.7 0.0 3.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain DUF2374 PF09574.10 KUM60702.1 - 0.07 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) Tir_receptor_C PF07489.11 KUM60702.1 - 0.94 9.4 4.4 1 9.3 4.4 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Dicty_REP PF05086.12 KUM60702.1 - 4.7 5.1 5.3 5.8 4.8 5.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RNase_T PF00929.24 KUM60703.1 - 8.9e-13 49.1 0.0 1.2e-12 48.7 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KUM60703.1 - 0.004 16.9 0.0 0.0094 15.7 0.0 1.6 2 0 0 2 2 2 1 3'-5' exonuclease Cwf_Cwc_15 PF04889.12 KUM60705.1 - 0.0077 16.0 0.0 0.018 14.8 0.0 1.5 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Aldedh PF00171.22 KUM60706.1 - 2.1e-142 474.9 0.0 2.5e-142 474.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KUM60706.1 - 0.00017 20.7 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Glyco_hydro_18 PF00704.28 KUM60708.1 - 6.4e-75 252.8 0.0 7.2e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.8 KUM60708.1 - 0.0089 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) LisH PF08513.11 KUM60709.1 - 5.9e-05 22.9 0.0 8.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 LisH ELL PF10390.9 KUM60709.1 - 0.0015 18.1 0.2 0.0018 17.8 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL TFIID_NTD2 PF04494.15 KUM60709.1 - 0.0033 17.7 0.1 0.01 16.1 0.0 1.7 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 KUM60710.1 - 1e-42 143.3 30.1 3.3e-08 34.0 0.6 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KUM60710.1 - 1.3e-18 67.5 0.0 1.9e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KUM60710.1 - 1.1e-11 44.9 0.6 0.069 13.5 0.0 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KUM60710.1 - 7.6e-07 28.2 3.6 0.0013 17.5 0.1 3.5 4 0 0 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KUM60710.1 - 0.00079 18.8 0.5 0.72 9.1 0.3 3.1 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 KUM60710.1 - 0.017 15.0 0.2 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF4550 PF15084.6 KUM60710.1 - 0.033 14.6 1.6 0.13 12.7 0.0 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4550) RAB3GAP2_N PF14655.6 KUM60710.1 - 0.2 10.9 0.2 4.9 6.3 0.0 2.7 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nucleoporin_N PF08801.11 KUM60710.1 - 0.28 9.9 0.7 20 3.8 0.0 2.9 2 1 1 3 3 3 0 Nup133 N terminal like Ge1_WD40 PF16529.5 KUM60710.1 - 0.73 8.7 3.1 39 3.0 0.1 3.7 4 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Abhydrolase_6 PF12697.7 KUM60711.1 - 4.3e-22 79.8 0.8 5.4e-22 79.5 0.2 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM60711.1 - 3.8e-06 26.8 0.0 1.6e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM60711.1 - 0.016 14.5 0.0 0.04 13.2 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KUM60711.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Methyltransf_32 PF13679.6 KUM60711.1 - 0.21 11.5 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.18 KUM60712.1 - 2e-07 30.4 0.0 3.4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH_1 PF00378.20 KUM60713.1 - 3.9e-28 98.4 0.0 5.3e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KUM60713.1 - 1.6e-14 54.2 0.0 4.5e-14 52.7 0.0 1.7 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase AidB_N PF18158.1 KUM60714.1 - 6.6e-18 65.1 0.0 1.3e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 KUM60714.1 - 1.3e-15 57.9 0.0 3.6e-15 56.5 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KUM60714.1 - 3.7e-11 43.1 0.0 1.2e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Flavi_M PF01004.19 KUM60714.1 - 0.021 14.6 0.1 0.079 12.7 0.1 2.0 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M Acyl-CoA_dh_2 PF08028.11 KUM60714.1 - 0.11 12.8 0.3 1.1 9.5 0.0 2.4 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Dala_Dala_lig_C PF07478.13 KUM60715.1 - 8.4e-27 94.0 0.0 1.1e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 KUM60715.1 - 0.00013 21.6 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KUM60715.1 - 0.00023 21.2 0.0 0.00045 20.3 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KUM60715.1 - 0.0073 16.1 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Fungal_trans PF04082.18 KUM60716.1 - 3e-09 36.3 0.0 4.7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAT PF03417.16 KUM60717.1 - 3e-12 46.7 0.0 1.1e-11 44.8 0.0 1.8 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase PIG-F PF06699.11 KUM60718.1 - 5.9e-66 222.1 4.4 7e-66 221.8 4.4 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_YMGG PF13441.6 KUM60718.1 - 0.11 12.3 2.9 0.59 9.9 2.9 2.0 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 KUM60718.1 - 1.2 9.2 7.0 8.8 6.4 0.3 2.3 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.15 KUM60718.1 - 2 8.3 6.1 6 6.8 0.2 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain ATPase_gene1 PF09527.10 KUM60718.1 - 8.7 6.6 16.6 0.36 11.0 0.3 4.0 4 0 0 4 4 4 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Fungal_trans PF04082.18 KUM60719.1 - 9.1e-05 21.6 0.0 9.9e-05 21.5 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2417 PF10329.9 KUM60720.1 - 3.9e-83 278.5 0.0 5.4e-83 278.0 0.0 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) DUF2070 PF09843.9 KUM60720.1 - 1.9 6.7 8.7 2.6 6.2 8.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ABC2_membrane_3 PF12698.7 KUM60720.1 - 6.2 5.8 10.6 9.1 5.3 10.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein NPL4 PF05021.15 KUM60721.1 - 7.2e-133 442.7 0.0 3.9e-124 414.0 0.0 2.1 1 1 1 2 2 2 2 NPL4 family zf-NPL4 PF05020.15 KUM60721.1 - 5.4e-68 227.7 0.1 8.4e-68 227.1 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KUM60721.1 - 0.00012 22.5 0.1 0.0026 18.2 0.0 2.8 2 1 0 2 2 2 1 Nuclear pore localisation protein NPL4 FMN_red PF03358.15 KUM60722.1 - 9.5e-08 31.9 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KUM60722.1 - 4.3e-07 29.8 0.0 5.5e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KUM60722.1 - 0.00034 20.8 0.3 0.0039 17.4 0.2 2.3 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KUM60722.1 - 0.017 15.4 0.0 0.037 14.3 0.0 1.5 1 1 1 2 2 2 0 Flavodoxin domain Ig_J_chain PF15097.6 KUM60723.1 - 0.0053 16.7 0.0 0.031 14.1 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin J chain SnoaL_2 PF12680.7 KUM60724.1 - 5e-06 27.1 0.2 6.3e-06 26.8 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.12 KUM60724.1 - 8.4e-05 22.7 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain ResIII PF04851.15 KUM60725.1 - 4.1e-21 75.7 0.0 7.6e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KUM60725.1 - 5.1e-20 71.9 0.0 1.9e-19 70.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KUM60725.1 - 9.4e-17 61.3 0.0 2.7e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KUM60725.1 - 0.027 14.8 0.0 0.07 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain SWI2_SNF2 PF18766.1 KUM60725.1 - 0.038 13.7 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase OAD_gamma PF04277.13 KUM60725.1 - 0.064 13.9 0.5 4.7 7.9 0.0 3.3 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Macoilin PF09726.9 KUM60726.1 - 7.6 4.9 8.1 7.9 4.9 8.1 1.1 1 0 0 1 1 1 0 Macoilin family F_actin_cap_B PF01115.17 KUM60727.1 - 3.7e-105 350.8 0.0 5.1e-105 350.4 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein, beta subunit HD PF01966.22 KUM60727.1 - 0.00058 20.1 0.1 0.002 18.4 0.1 1.9 1 1 0 1 1 1 1 HD domain Med11 PF10280.9 KUM60728.1 - 2.7e-39 134.8 0.1 3.3e-39 134.5 0.1 1.1 1 0 0 1 1 1 1 Mediator complex protein DUF5326 PF17260.2 KUM60729.1 - 0.005 17.0 0.5 0.0079 16.3 0.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5326) DUF3377 PF11857.8 KUM60729.1 - 0.054 13.4 0.2 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF4083 PF13314.6 KUM60729.1 - 0.066 13.2 0.4 0.11 12.5 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Gram_pos_anchor PF00746.21 KUM60729.1 - 0.14 12.2 0.7 0.28 11.2 0.7 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif PUF PF00806.19 KUM60730.1 - 8.2e-61 198.4 11.8 8.4e-10 37.8 0.3 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KUM60730.1 - 0.015 15.6 2.3 16 5.8 0.2 4.2 1 1 2 3 3 3 0 CPL (NUC119) domain DUF234 PF03008.14 KUM60730.1 - 0.1 13.1 0.9 0.53 10.8 0.1 2.5 3 0 0 3 3 3 0 Archaea bacterial proteins of unknown function PLN_propep PF16485.5 KUM60730.1 - 0.16 11.7 0.4 0.55 10.0 0.1 2.1 2 0 0 2 2 2 0 Protealysin propeptide LOB PF03195.14 KUM60730.1 - 0.57 10.8 2.4 5.8 7.6 0.2 3.6 3 1 2 5 5 5 0 Lateral organ boundaries (LOB) domain ParD PF09386.10 KUM60730.1 - 0.64 10.4 2.2 89 3.6 0.0 4.3 3 2 2 5 5 5 0 Antitoxin ParD cwf21 PF08312.12 KUM60731.1 - 1.2e-16 60.5 20.1 1.2e-16 60.5 20.1 2.2 2 1 0 2 2 2 1 cwf21 domain DUF1690 PF07956.11 KUM60731.1 - 1.9 8.9 12.1 0.4 11.1 8.8 1.4 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) RRN3 PF05327.11 KUM60731.1 - 6.4 5.2 6.3 7 5.1 6.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4637 PF15470.6 KUM60731.1 - 7.5 6.3 12.7 8.5 6.1 11.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4637) HA2 PF04408.23 KUM60732.1 - 8.7e-28 96.8 0.0 8.7e-28 96.8 0.0 2.8 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KUM60732.1 - 5.4e-12 46.0 0.0 2.2e-11 44.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KUM60732.1 - 3.3e-08 33.8 0.0 8.2e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KUM60732.1 - 9.8e-08 32.0 0.0 8.1e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KUM60732.1 - 0.0027 18.0 0.5 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KUM60732.1 - 0.0045 17.3 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KUM60732.1 - 0.0056 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KUM60732.1 - 0.007 15.6 0.8 0.012 14.9 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 KUM60732.1 - 0.038 14.5 0.0 0.038 14.5 0.0 4.0 4 1 0 4 4 4 0 AAA domain T2SSE PF00437.20 KUM60732.1 - 0.04 13.0 0.0 0.091 11.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 KUM60732.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 KUM60732.1 - 0.35 10.8 2.9 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ResIII PF04851.15 KUM60732.1 - 0.69 9.9 8.4 2.8 7.9 0.0 3.3 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit TFIID_20kDa PF03847.13 KUM60733.1 - 0.0095 16.4 0.1 0.025 15.1 0.1 1.7 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CCDC50_N PF15295.6 KUM60733.1 - 7.6 6.7 9.1 24 5.1 0.1 3.2 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 50 N-terminus ABC2_membrane PF01061.24 KUM60734.1 - 1.6e-78 262.9 54.4 1e-41 142.7 19.1 3.0 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 KUM60734.1 - 9.8e-39 133.0 0.0 4.4e-20 72.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KUM60734.1 - 2.1e-25 88.4 18.0 4e-25 87.5 0.0 3.4 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KUM60734.1 - 1.9e-16 60.5 2.5 2.9e-16 59.9 0.9 2.3 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KUM60734.1 - 6.8e-06 26.6 0.1 0.0069 16.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KUM60734.1 - 1.7e-05 25.4 0.0 0.0022 18.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KUM60734.1 - 2.4e-05 24.3 0.1 0.01 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KUM60734.1 - 3.2e-05 24.1 0.0 0.0055 16.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KUM60734.1 - 5.9e-05 23.0 0.2 0.00081 19.3 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 KUM60734.1 - 0.00018 21.2 0.4 0.007 16.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KUM60734.1 - 0.00044 20.5 4.8 0.003 17.8 0.2 3.0 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 KUM60734.1 - 0.0011 18.5 0.5 0.27 10.8 0.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KUM60734.1 - 0.0016 18.7 0.2 0.052 13.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KUM60734.1 - 0.002 17.9 0.1 0.18 11.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.7 KUM60734.1 - 0.0024 17.0 16.1 0.0024 17.0 16.1 3.4 4 0 0 4 4 3 1 ABC-2 family transporter protein NACHT PF05729.12 KUM60734.1 - 0.0025 17.7 1.3 0.15 12.0 0.5 2.4 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 KUM60734.1 - 0.0032 17.2 0.4 0.5 10.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KUM60734.1 - 0.0037 16.7 0.1 0.051 13.0 0.0 2.7 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KUM60734.1 - 0.0044 17.1 0.3 0.092 12.8 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase TsaE PF02367.17 KUM60734.1 - 0.0057 16.6 0.5 0.66 10.0 0.4 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KUM60734.1 - 0.0062 17.0 0.0 5.3 7.5 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KUM60734.1 - 0.038 13.7 2.0 2.9 7.6 0.5 2.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KUM60734.1 - 0.061 12.4 0.0 3.3 6.7 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein APS_kinase PF01583.20 KUM60734.1 - 0.085 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 KUM60734.1 - 0.13 11.4 0.3 4.4 6.4 0.2 2.3 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.18 KUM60734.1 - 0.14 11.5 0.3 0.4 9.9 0.0 1.8 2 0 0 2 2 2 0 Septin Zeta_toxin PF06414.12 KUM60734.1 - 0.16 11.2 2.6 0.93 8.7 0.4 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 KUM60734.1 - 0.24 11.7 3.0 7.9 6.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KUM60734.1 - 0.31 10.7 1.2 0.58 9.7 0.3 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Dynamin_N PF00350.23 KUM60734.1 - 1.7 8.7 4.2 1.8 8.6 0.0 3.0 4 0 0 4 4 3 0 Dynamin family AAA_17 PF13207.6 KUM60734.1 - 8.8 6.8 7.9 1.4 9.3 0.4 2.8 3 0 0 3 3 2 0 AAA domain CDP-OH_P_transf PF01066.21 KUM60735.1 - 9.4e-15 55.1 0.8 9.4e-15 55.1 0.8 2.0 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Phosphodiest PF01663.22 KUM60736.1 - 3.7e-15 56.4 0.1 5.8e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KUM60736.1 - 7.1e-06 25.6 0.4 1.5e-05 24.5 0.2 1.5 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 KUM60736.1 - 1.2e-05 24.8 0.1 2.3e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.12 KUM60736.1 - 0.14 12.2 1.1 13 5.9 0.1 2.3 2 0 0 2 2 2 0 PglZ domain Peptidase_M22 PF00814.25 KUM60737.1 - 9.3e-85 284.6 0.0 1.1e-84 284.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KUM60737.1 - 0.00033 20.4 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 2 Carbamoyltransferase N-terminus Tyr-DNA_phospho PF06087.12 KUM60738.1 - 5.7e-82 275.9 0.0 8.3e-82 275.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 KUM60738.1 - 0.00026 20.9 0.0 0.03 14.2 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.20 KUM60738.1 - 0.0017 18.1 0.5 0.0017 18.1 0.5 3.0 3 0 0 3 3 3 2 Ubiquitin interaction motif Glyco_hydro_16 PF00722.21 KUM60739.1 - 1.4e-42 145.2 3.9 1.4e-42 145.2 3.9 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 CIA30 PF08547.12 KUM60739.1 - 0.021 14.8 0.5 0.038 14.0 0.5 1.5 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) MGC-24 PF05283.11 KUM60739.1 - 1.4 9.4 13.0 0.49 10.8 6.6 2.5 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Zn_clus PF00172.18 KUM60740.1 - 4.3e-07 29.9 12.1 4.3e-07 29.9 12.1 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM60740.1 - 1.2e-06 27.7 0.3 2.3e-06 26.9 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1667 PF07892.11 KUM60740.1 - 0.16 12.0 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) DUF3384 PF11864.8 KUM60741.1 - 2.5e-110 369.7 5.5 2.5e-110 369.7 5.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KUM60741.1 - 2.5e-46 157.6 0.0 4.1e-46 156.9 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KUM60741.1 - 1.3e-39 136.3 0.0 4.6e-34 118.1 0.0 3.3 3 0 0 3 3 3 3 Tuberin U3snoRNP10 PF12397.8 KUM60741.1 - 0.11 12.8 0.1 6 7.2 0.0 2.9 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 CTP_synth_N PF06418.14 KUM60742.1 - 2.6e-121 403.9 0.0 3.5e-121 403.5 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KUM60742.1 - 2e-54 184.2 0.0 3.6e-54 183.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KUM60742.1 - 3.4e-06 27.0 0.3 2.7e-05 24.0 0.3 2.2 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 KUM60742.1 - 0.08 13.0 0.0 0.22 11.6 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain CAS_CSE1 PF03378.15 KUM60743.1 - 1.1e-196 653.6 1.2 1.6e-196 653.1 0.5 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KUM60743.1 - 4.8e-159 529.1 1.7 7.1e-159 528.5 1.7 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KUM60743.1 - 1.4e-15 57.0 0.2 6.9e-15 54.7 0.2 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF1529 PF07485.11 KUM60743.1 - 0.0017 18.3 0.0 0.041 13.8 0.0 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1259) Xpo1 PF08389.12 KUM60743.1 - 0.028 14.5 3.1 0.3 11.1 0.0 3.6 5 0 0 5 5 5 0 Exportin 1-like protein RF-1 PF00472.20 KUM60744.1 - 4.9e-26 90.9 2.0 8.2e-26 90.2 2.0 1.3 1 0 0 1 1 1 1 RF-1 domain TFIIA PF03153.13 KUM60746.1 - 2.7 7.9 7.6 4 7.3 7.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1180 PF06679.12 KUM60747.1 - 0.74 10.2 6.1 0.86 10.0 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) BTB PF00651.31 KUM60748.1 - 6.1e-14 52.2 0.2 1.6e-13 50.8 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain GlnD_UR_UTase PF08335.11 KUM60748.1 - 0.039 14.1 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase SNF2_N PF00176.23 KUM60749.1 - 4.9e-60 203.1 0.0 9.2e-60 202.2 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.25 KUM60749.1 - 9.1e-08 31.9 7.3 2.9e-07 30.2 7.3 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KUM60749.1 - 1.8e-07 30.9 8.0 1.8e-07 30.9 8.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KUM60749.1 - 2.2e-07 30.6 7.3 5.4e-07 29.4 7.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KUM60749.1 - 4.6e-06 26.9 9.6 1.3e-05 25.4 9.6 1.9 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KUM60749.1 - 2.3e-05 24.1 6.9 5.2e-05 23.0 6.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KUM60749.1 - 0.00053 19.9 7.8 0.0014 18.5 7.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KUM60749.1 - 0.00088 19.5 7.1 0.0032 17.7 7.1 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KUM60749.1 - 0.0025 17.8 6.0 0.0075 16.3 6.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KUM60749.1 - 0.015 15.4 7.0 0.036 14.2 7.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Helicase_C PF00271.31 KUM60749.1 - 0.044 14.1 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Acyltransferase PF01553.21 KUM60749.1 - 0.075 12.7 0.0 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 Acyltransferase TPR_2 PF07719.17 KUM60749.1 - 0.11 12.7 0.2 0.4 10.9 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Zn_ribbon_17 PF17120.5 KUM60749.1 - 0.74 9.5 7.8 1.6 8.4 7.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KUM60749.1 - 0.98 9.3 7.9 0.68 9.8 5.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain IBR PF01485.21 KUM60749.1 - 5.8 7.2 8.4 2.1 8.6 4.8 2.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain DnaJ PF00226.31 KUM60750.1 - 1.6e-09 37.7 0.4 5.9e-09 35.9 0.4 2.0 1 0 0 1 1 1 1 DnaJ domain DnaJ PF00226.31 KUM60751.1 - 2.8e-20 72.2 1.4 4.4e-20 71.6 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 KUM60751.1 - 0.16 12.3 2.6 0.24 11.7 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.6 KUM60751.1 - 0.25 11.4 10.6 0.48 10.5 10.6 1.4 1 0 0 1 1 1 0 Glycine zipper Bacteriocin_IIc PF10439.9 KUM60751.1 - 0.59 10.3 8.2 1 9.5 8.2 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.6 KUM60751.1 - 6.9 6.5 15.0 11 5.9 3.7 2.0 1 1 1 2 2 2 0 YMGG-like Gly-zipper PMM PF03332.13 KUM60752.1 - 9.8e-100 332.8 0.2 1.1e-99 332.6 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KUM60752.1 - 0.0024 17.7 0.0 0.012 15.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KUM60752.1 - 0.01 15.4 0.0 2.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase TMPIT PF07851.13 KUM60752.1 - 0.064 12.5 0.0 0.087 12.1 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1640 PF07798.11 KUM60753.1 - 4.1e-56 189.8 8.1 4.9e-56 189.5 8.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) PNGaseA PF12222.8 KUM60754.1 - 2.5e-185 616.5 2.5 3.1e-185 616.1 2.5 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Ecm29 PF13001.7 KUM60755.1 - 2.7e-162 540.9 0.0 3.8e-160 533.8 0.0 2.7 2 0 0 2 2 2 2 Proteasome stabiliser HEAT_EZ PF13513.6 KUM60755.1 - 2.6e-07 31.0 6.8 0.84 10.2 0.0 8.7 9 1 1 10 10 10 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KUM60755.1 - 1.4e-05 25.6 0.1 0.029 15.0 0.1 5.2 6 2 2 8 8 8 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KUM60755.1 - 0.019 15.2 7.8 6 7.4 0.1 6.7 7 0 0 7 7 7 0 HEAT repeat CoatB PF10389.9 KUM60756.1 - 2 8.3 5.1 1.3 8.9 0.6 2.3 2 0 0 2 2 2 0 Bacteriophage coat protein B FAA_hydrolase PF01557.18 KUM60757.1 - 4.8e-66 222.5 0.0 6e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 KUM60757.1 - 0.027 14.9 0.4 0.046 14.1 0.4 1.3 1 0 0 1 1 1 0 Type II transport protein GspH HSP20 PF00011.21 KUM60758.1 - 3.8e-16 59.1 0.0 6.8e-11 42.2 0.0 2.1 1 1 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KUM60758.1 - 0.0014 18.1 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 2 HSP20-like domain found in ArsA WD40 PF00400.32 KUM60759.1 - 8e-18 64.5 8.7 0.0002 22.1 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM60759.1 - 6.1e-07 29.6 0.1 0.024 14.9 0.0 4.6 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3642 PF12182.8 KUM60759.1 - 0.17 12.2 0.0 0.81 10.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial lipoprotein Lipase_3 PF01764.25 KUM60760.1 - 6.1e-29 100.7 0.0 1.1e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KUM60760.1 - 0.001 18.4 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KUM60760.1 - 0.0041 17.8 2.7 0.0063 17.1 1.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KUM60760.1 - 0.021 14.5 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 KUM60760.1 - 0.042 13.5 0.0 0.062 12.9 0.0 1.1 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 KUM60760.1 - 0.095 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 KUM60760.1 - 0.11 12.5 0.1 0.18 11.9 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.8 KUM60760.1 - 0.27 10.8 0.0 1 8.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) RRM_1 PF00076.22 KUM60762.1 - 3.1e-07 30.1 0.1 5.8e-07 29.2 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KUM60762.1 - 3.5e-05 23.4 0.0 4.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 KUM60762.1 - 0.0036 17.1 0.6 0.012 15.4 0.2 2.1 1 1 1 2 2 2 1 Calcipressin Prim-Pol PF09250.11 KUM60762.1 - 0.067 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Fungal_trans_2 PF11951.8 KUM60763.1 - 3.6e-07 29.3 0.0 3.9e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KUM60764.1 - 5.8e-06 25.4 2.3 8.5e-06 24.8 2.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain WW PF00397.26 KUM60766.1 - 1e-11 44.7 0.4 2.5e-11 43.5 0.4 1.8 1 0 0 1 1 1 1 WW domain UCR_Fe-S_N PF10399.9 KUM60766.1 - 4.7 6.6 8.8 14 5.1 8.8 1.8 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal PRA1 PF03208.19 KUM60767.1 - 2.6e-37 127.6 0.8 3.1e-37 127.4 0.8 1.0 1 0 0 1 1 1 1 PRA1 family protein Frag1 PF10277.9 KUM60769.1 - 1.4e-40 139.2 2.5 1.6e-40 139.0 2.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family CPP1-like PF11833.8 KUM60769.1 - 0.11 12.2 3.4 0.2 11.3 0.8 2.2 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Bax1-I PF01027.20 KUM60769.1 - 0.22 11.3 8.5 6.9 6.4 6.4 2.3 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF3087 PF11286.8 KUM60769.1 - 0.73 9.3 3.5 6.4 6.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Tetraspanin PF00335.20 KUM60769.1 - 4.3 7.0 9.3 5.4 6.6 2.4 2.1 1 1 1 2 2 2 0 Tetraspanin family Glyco_hydro_35 PF01301.19 KUM60770.1 - 1.1e-80 271.7 4.7 1.6e-80 271.1 4.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KUM60770.1 - 1.3e-58 196.5 0.9 2.1e-31 108.9 0.0 3.0 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KUM60770.1 - 1.1e-53 181.7 4.2 1.1e-53 181.7 4.2 1.7 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KUM60770.1 - 6.4e-24 83.3 0.9 2.1e-23 81.7 0.7 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 KUM60770.1 - 3.8e-08 33.1 1.9 0.0038 16.7 0.0 3.3 2 1 0 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Y_phosphatase3 PF13350.6 KUM60771.1 - 4.8e-15 56.2 0.1 4.9e-15 56.1 0.1 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF2291 PF10054.9 KUM60771.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) PhzC-PhzF PF02567.16 KUM60772.1 - 1.6e-41 142.7 0.0 1.9e-41 142.4 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 KUM60772.1 - 0.022 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Proline racemase KH_8 PF17903.1 KUM60773.1 - 0.00012 22.1 0.0 0.00025 21.0 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KUM60773.1 - 0.022 14.6 1.0 0.048 13.5 1.0 1.6 1 0 0 1 1 1 0 KH domain MDM31_MDM32 PF08118.11 KUM60774.1 - 6e-250 830.4 0.1 1e-249 829.6 0.1 1.3 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins HCNGP PF07818.13 KUM60775.1 - 5.7e-31 107.0 0.9 1.1e-30 106.1 0.9 1.5 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.26 KUM60776.1 - 4.3e-32 111.1 0.8 7.8e-31 107.0 0.8 2.1 1 1 0 1 1 1 1 Proteasome subunit Proteasome PF00227.26 KUM60777.1 - 1.6e-29 102.8 0.0 1.9e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Glyco_hydro_4 PF02056.16 KUM60777.1 - 0.033 13.7 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase SLIDE PF09111.10 KUM60778.1 - 0.035 14.1 0.3 0.18 11.9 0.1 2.1 3 0 0 3 3 3 0 SLIDE adh_short PF00106.25 KUM60779.1 - 3.3e-32 111.5 0.0 5.2e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM60779.1 - 4.4e-24 85.3 0.0 9e-24 84.3 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM60779.1 - 0.0031 17.4 0.8 0.028 14.3 0.2 2.5 2 1 0 2 2 2 1 KR domain TRI12 PF06609.13 KUM60780.1 - 2.9e-35 121.8 23.5 3.7e-35 121.4 23.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KUM60780.1 - 1.7e-06 27.3 41.8 1.7e-06 27.3 41.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3087 PF11286.8 KUM60780.1 - 0.38 10.2 3.5 12 5.4 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) adh_short PF00106.25 KUM60781.1 - 5.6e-44 149.9 0.0 7e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM60781.1 - 8.2e-32 110.6 0.0 1.2e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM60781.1 - 9.5e-08 32.2 0.1 2.1e-07 31.0 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KUM60781.1 - 0.0018 17.8 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KUM60781.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding GHMP_kinases_N PF00288.26 KUM60782.1 - 1.4e-05 25.2 0.6 3e-05 24.2 0.2 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KUM60782.1 - 0.00069 19.9 0.0 0.0034 17.7 0.1 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal Peptidase_A4 PF01828.17 KUM60783.1 - 4.9e-81 271.2 11.2 6e-81 270.9 11.2 1.1 1 0 0 1 1 1 1 Peptidase A4 family MF_alpha_N PF05436.11 KUM60783.1 - 0.21 11.5 1.0 0.42 10.5 0.5 1.8 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus IspD PF01128.19 KUM60785.1 - 1.9e-57 194.6 0.0 2.4e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YgbB PF02542.16 KUM60785.1 - 9.3e-52 175.4 0.1 1.6e-51 174.6 0.1 1.4 1 0 0 1 1 1 1 YgbB family NTP_transf_3 PF12804.7 KUM60785.1 - 1.4e-10 41.8 0.1 2.4e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain LysM PF01476.20 KUM60786.1 - 0.0017 18.3 0.8 0.003 17.6 0.0 1.8 2 0 0 2 2 2 1 LysM domain Ank_4 PF13637.6 KUM60789.1 - 2.9e-48 161.7 2.7 1.1e-11 45.0 0.0 8.3 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 KUM60789.1 - 6.8e-45 151.6 7.5 1.5e-13 51.1 0.2 5.9 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KUM60789.1 - 2.3e-36 119.6 11.0 0.0013 19.1 0.0 10.6 11 0 0 11 11 11 9 Ankyrin repeat Ank PF00023.30 KUM60789.1 - 5.9e-30 102.4 23.6 0.00099 19.5 0.1 10.1 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 KUM60789.1 - 2.2e-26 91.6 4.5 9.9e-05 22.6 0.0 7.6 2 2 5 7 7 7 7 Ankyrin repeats (many copies) INTS5_N PF14837.6 KUM60789.1 - 0.00067 19.3 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Integrator complex subunit 5 N-terminus DUF1843 PF08898.10 KUM60789.1 - 0.14 12.7 21.7 14 6.2 1.5 7.5 6 2 1 7 7 7 0 Domain of unknown function (DUF1843) Bactofilin PF04519.13 KUM60789.1 - 0.79 10.1 4.4 59 4.0 0.0 4.1 5 1 0 5 5 5 0 Polymer-forming cytoskeletal CDC37_N PF03234.14 KUM60790.1 - 0.14 13.0 1.0 0.24 12.3 1.0 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF5541 PF17695.1 KUM60791.1 - 0.2 12.1 0.0 0.34 11.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5541) TBCC_N PF16752.5 KUM60792.1 - 0.0028 18.1 0.4 1.1 9.7 0.1 2.3 1 1 1 2 2 2 2 Tubulin-specific chaperone C N-terminal domain ABC_tran PF00005.27 KUM60794.1 - 4e-52 176.4 0.0 4e-28 98.6 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KUM60794.1 - 3.2e-28 99.2 29.6 4.9e-21 75.6 14.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KUM60794.1 - 6.7e-10 38.8 3.5 0.0064 15.9 0.1 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KUM60794.1 - 2.5e-06 27.1 0.9 0.0013 18.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KUM60794.1 - 5.7e-06 26.3 0.6 0.00071 19.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KUM60794.1 - 1.1e-05 25.9 0.1 0.0043 17.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KUM60794.1 - 3.7e-05 23.7 7.1 0.00098 19.0 0.1 3.6 3 1 1 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KUM60794.1 - 9.1e-05 22.7 1.4 0.019 15.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KUM60794.1 - 9.9e-05 22.8 0.3 0.086 13.3 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KUM60794.1 - 0.00022 20.8 0.6 0.32 10.5 0.2 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 KUM60794.1 - 0.00032 21.2 4.4 0.05 14.1 0.6 2.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KUM60794.1 - 0.00061 19.8 0.1 0.47 10.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KUM60794.1 - 0.00064 20.1 0.0 0.28 11.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 KUM60794.1 - 0.0007 19.2 0.1 0.031 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KUM60794.1 - 0.0008 19.2 0.4 0.58 9.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 KUM60794.1 - 0.0014 18.3 0.4 1.5 8.4 0.1 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain T2SSE PF00437.20 KUM60794.1 - 0.0024 17.0 0.2 0.16 11.0 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein NB-ARC PF00931.22 KUM60794.1 - 0.0027 17.0 0.3 1.4 8.1 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_15 PF13175.6 KUM60794.1 - 0.0039 17.0 2.3 0.04 13.6 0.1 2.6 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KUM60794.1 - 0.0039 17.1 0.0 0.31 10.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 KUM60794.1 - 0.0091 15.7 2.9 7.2 6.3 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_33 PF13671.6 KUM60794.1 - 0.011 15.9 0.0 0.51 10.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KUM60794.1 - 0.012 15.9 0.6 16 5.7 0.0 3.6 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 KUM60794.1 - 0.013 15.5 0.5 1.2 9.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KUM60794.1 - 0.016 14.9 0.1 2.1 8.1 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KUM60794.1 - 0.034 14.5 0.1 13 6.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KUM60794.1 - 0.039 13.9 0.1 0.86 9.5 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea cobW PF02492.19 KUM60794.1 - 0.048 13.3 1.2 3.6 7.1 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KUM60794.1 - 0.067 13.1 1.3 6 6.7 0.1 2.5 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 KUM60794.1 - 0.092 12.5 0.3 6.5 6.4 0.0 2.6 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 KUM60794.1 - 0.11 11.7 0.1 2.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DEAD PF00270.29 KUM60794.1 - 0.11 12.2 0.2 0.34 10.7 0.2 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_18 PF13238.6 KUM60794.1 - 0.11 13.0 0.1 6.3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 KUM60794.1 - 0.14 12.0 0.2 22 5.0 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.23 KUM60794.1 - 0.14 12.2 0.2 3.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Dynamin family PIF1 PF05970.14 KUM60794.1 - 0.16 11.1 0.0 0.68 9.0 0.0 1.9 2 0 0 2 2 2 0 PIF1-like helicase TsaE PF02367.17 KUM60794.1 - 0.17 11.9 0.2 23 5.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 KUM60794.1 - 0.17 11.2 0.1 4.6 6.5 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_11 PF13086.6 KUM60794.1 - 0.19 11.5 0.0 18 5.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KUM60794.1 - 0.21 11.5 0.3 0.53 10.2 0.3 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_ATPase PF09818.9 KUM60794.1 - 0.58 8.9 6.1 0.26 10.1 0.3 2.9 4 0 0 4 4 4 0 Predicted ATPase of the ABC class Nup160 PF11715.8 KUM60795.1 - 1.7e-157 525.4 0.6 2.5e-157 524.8 0.6 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Rad51 PF08423.11 KUM60796.1 - 1e-128 428.0 0.0 1.3e-128 427.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KUM60796.1 - 5.1e-10 39.2 0.0 7.5e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KUM60796.1 - 2.1e-09 37.3 0.0 2.9e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KUM60796.1 - 7.4e-07 29.7 0.3 2.7e-06 27.9 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 KUM60796.1 - 0.00016 21.1 0.9 0.00083 18.8 0.9 2.1 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KUM60796.1 - 0.0078 15.6 0.1 0.041 13.2 0.0 1.9 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain ssDNA_TraI_N PF18272.1 KUM60796.1 - 0.087 12.8 0.2 0.58 10.2 0.1 2.3 3 0 0 3 3 3 0 single-stranded DNA binding TraI N-terminal subdomain AAA_22 PF13401.6 KUM60796.1 - 0.14 12.4 0.3 0.65 10.3 0.2 2.1 2 1 0 2 2 2 0 AAA domain PAXNEB PF05625.11 KUM60796.1 - 0.24 10.5 2.0 0.69 9.0 0.9 1.9 1 1 1 2 2 2 0 PAXNEB protein Condensation PF00668.20 KUM60797.1 - 9.3e-07 27.9 0.1 2.3e-05 23.3 0.1 2.0 1 1 0 1 1 1 1 Condensation domain TA_inhibitor PF17574.2 KUM60797.1 - 0.00024 21.1 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of toxin/antitoxin system (Gp4.5) YfkB PF08756.10 KUM60797.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 YfkB-like domain Catalase PF00199.19 KUM60798.1 - 5.8e-174 578.7 0.0 6.8e-174 578.4 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KUM60798.1 - 4.5e-12 46.0 0.1 1.2e-11 44.7 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Mito_carr PF00153.27 KUM60800.1 - 1.9e-68 226.5 1.4 2.1e-23 82.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Chromate_transp PF02417.15 KUM60800.1 - 0.12 12.5 0.8 4 7.5 0.1 2.4 2 0 0 2 2 2 0 Chromate transporter adh_short PF00106.25 KUM60801.1 - 1.9e-15 56.9 0.1 2.3e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM60801.1 - 9.1e-09 35.2 0.1 1.4e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM60801.1 - 2.8e-05 24.1 0.1 3.4e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM60801.1 - 0.0058 16.1 0.0 0.0078 15.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Rib_hydrolayse PF02267.17 KUM60802.1 - 0.037 13.4 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosyl cyclase Ribonuc_L-PSP PF01042.21 KUM60804.1 - 2e-36 124.6 0.0 2.2e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP AFG1_ATPase PF03969.16 KUM60805.1 - 5.2e-97 325.0 0.0 2.7e-92 309.5 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.6 KUM60805.1 - 0.0015 18.8 0.0 0.011 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KUM60805.1 - 0.0023 18.3 0.0 0.92 9.9 0.0 3.2 2 1 0 3 3 3 1 AAA ATPase domain Bac_DnaA PF00308.18 KUM60805.1 - 0.0054 16.6 0.4 1.4 8.7 0.1 2.4 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_14 PF13173.6 KUM60805.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KUM60805.1 - 0.011 16.2 0.0 0.048 14.1 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KUM60805.1 - 0.014 15.8 0.0 0.094 13.1 0.0 2.4 3 0 0 3 3 3 0 RNA helicase SH3_1 PF00018.28 KUM60806.1 - 6.1e-26 89.8 0.0 1.6e-11 43.6 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KUM60806.1 - 7.3e-15 54.6 0.1 5.4e-07 29.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KUM60806.1 - 1.6e-13 50.7 0.0 3.2e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 KUM60806.1 - 2.9e-08 33.3 0.0 8.3e-05 22.2 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 KUM60806.1 - 3.9e-07 29.9 0.4 8.3e-07 28.9 0.4 1.6 1 0 0 1 1 1 1 PB1 domain SAC3_GANP PF03399.16 KUM60807.1 - 9.6e-24 84.3 0.8 1.4e-21 77.2 0.8 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KUM60807.1 - 0.0017 18.4 0.1 0.0038 17.2 0.1 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family EAP30 PF04157.16 KUM60808.1 - 1.3e-41 142.5 0.1 1.7e-41 142.1 0.1 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 KUM60808.1 - 4.5e-23 80.4 2.7 4.5e-23 80.4 2.7 2.4 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Vps36_ESCRT-II PF11605.8 KUM60808.1 - 1.5e-22 79.5 0.0 2.7e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 KUM60808.1 - 0.00015 21.0 13.0 0.00076 18.7 1.1 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 KUM60808.1 - 0.00017 21.6 4.4 0.033 14.2 0.6 2.4 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger GRAM PF02893.20 KUM60808.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 GRAM domain DZR PF12773.7 KUM60808.1 - 0.14 12.2 4.6 0.17 11.9 0.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon Fungal_trans PF04082.18 KUM60809.1 - 2.2e-09 36.8 0.8 2.2e-09 36.8 0.8 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain SH3_7 PF12914.7 KUM60809.1 - 0.12 12.5 0.0 0.38 11.0 0.0 1.9 1 0 0 1 1 1 0 SH3 domain of SH3b2 type Glyco_hydro_2_N PF02837.18 KUM60810.1 - 0.00019 21.4 0.0 0.00039 20.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_79C PF16862.5 KUM60811.1 - 2.3e-17 63.7 0.0 4.6e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Catalase PF00199.19 KUM60813.1 - 5.1e-168 559.1 0.0 6.4e-168 558.8 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KUM60813.1 - 2e-18 66.3 0.1 4.8e-18 65.1 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.24 KUM60813.1 - 1.9e-09 37.5 0.1 5.6e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 DJ-1/PfpI family Catalase_C PF18011.1 KUM60813.1 - 3.7e-09 36.4 0.2 1.2e-08 34.7 0.1 1.9 2 0 0 2 2 2 1 C-terminal domain found in long catalases EST1 PF10374.9 KUM60813.1 - 0.15 12.7 0.0 0.29 11.8 0.0 1.4 1 0 0 1 1 1 0 Telomerase activating protein Est1 Cation_efflux PF01545.21 KUM60814.1 - 2.8e-50 170.9 3.4 4e-50 170.3 3.4 1.2 1 0 0 1 1 1 1 Cation efflux family PAP2_3 PF14378.6 KUM60814.1 - 0.0076 16.0 3.1 0.13 11.9 0.1 2.4 2 0 0 2 2 2 2 PAP2 superfamily BPD_transp_2 PF02653.16 KUM60814.1 - 0.016 14.4 2.0 0.016 14.4 2.0 2.0 2 1 0 2 2 2 0 Branched-chain amino acid transport system / permease component Amidase PF01425.21 KUM60815.1 - 1.2e-97 327.7 0.0 1.8e-97 327.1 0.0 1.2 1 0 0 1 1 1 1 Amidase Methyltransf_11 PF08241.12 KUM60816.1 - 1.9e-11 44.5 0.0 3.4e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM60816.1 - 1.3e-10 41.8 0.0 2.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM60816.1 - 1.5e-06 28.9 0.0 2.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KUM60816.1 - 0.00095 18.9 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KUM60816.1 - 0.002 18.0 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM60816.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.12 KUM60816.1 - 0.047 13.2 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Acetyltransf_3 PF13302.7 KUM60817.1 - 2.3e-14 54.2 0.0 3.1e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM60817.1 - 9.4e-05 22.6 0.0 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KUM60817.1 - 0.0038 17.4 0.0 0.0056 16.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KUM60818.1 - 8.9e-28 97.2 61.0 2.2e-23 82.8 42.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3681 PF12442.8 KUM60818.1 - 0.081 13.4 6.0 0.056 13.9 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) Chitin_synth_1 PF01644.17 KUM60819.1 - 1.6e-77 259.1 0.0 2.4e-77 258.5 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KUM60819.1 - 3.8e-26 90.8 0.1 7.7e-26 89.8 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KUM60819.1 - 1.5e-22 80.0 3.4 5.1e-20 71.6 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KUM60819.1 - 1.7e-07 31.4 0.3 1.7e-07 31.4 0.3 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KUM60819.1 - 0.0089 15.9 0.0 0.042 13.7 0.0 1.9 1 1 1 2 2 2 1 Glycosyltransferase like family 2 DUF1774 PF08611.10 KUM60820.1 - 4.2e-34 116.7 3.7 4.2e-34 116.7 3.7 2.1 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Inositol_P PF00459.25 KUM60821.1 - 5.4e-39 134.3 0.1 1.4e-38 133.0 0.1 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family Peptidase_M28 PF04389.17 KUM60822.1 - 2.7e-29 102.3 0.0 4.8e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KUM60822.1 - 7.3e-08 32.3 0.1 1.5e-07 31.3 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 R3H-assoc PF13902.6 KUM60823.1 - 2.6e-23 82.9 3.0 6.3e-23 81.6 3.0 1.7 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 KUM60823.1 - 0.015 15.3 0.2 0.15 12.0 0.0 2.4 2 0 0 2 2 2 0 R3H domain dsrm PF00035.26 KUM60825.1 - 0.01 16.5 0.1 0.022 15.4 0.1 1.6 1 1 0 1 1 1 0 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KUM60825.1 - 0.02 15.2 0.1 0.18 12.1 0.1 2.1 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Sugar_tr PF00083.24 KUM60827.1 - 2.1e-47 162.0 10.0 2.4e-47 161.8 10.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM60827.1 - 0.052 12.5 17.8 0.0058 15.6 11.8 1.9 1 1 1 2 2 2 0 Major Facilitator Superfamily Ferric_reduct PF01794.19 KUM60827.1 - 1.6 8.9 7.1 0.12 12.5 0.8 2.1 2 1 0 2 2 2 0 Ferric reductase like transmembrane component bZIP_1 PF00170.21 KUM60828.1 - 2.8e-09 36.9 12.6 6.1e-09 35.8 12.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KUM60828.1 - 1.1e-05 25.4 11.3 1.1e-05 25.4 11.3 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KUM60828.1 - 0.32 11.6 10.6 0.15 12.6 8.0 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor RGS12_us1 PF16613.5 KUM60828.1 - 2.3 8.6 5.3 13 6.2 1.4 2.5 2 0 0 2 2 2 0 Unstructured region of RGS12 DUF349 PF03993.12 KUM60828.1 - 5 7.5 10.0 0.41 11.0 5.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Kinesin PF00225.23 KUM60830.1 - 3.3e-112 374.7 0.0 5.2e-112 374.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KUM60830.1 - 8.8e-27 93.9 0.2 5.7e-26 91.2 0.0 2.4 3 0 0 3 3 3 1 Microtubule binding Spc7 PF08317.11 KUM60830.1 - 0.0029 16.6 10.4 0.0064 15.4 10.4 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein RE_HindIII PF09518.10 KUM60830.1 - 0.11 11.8 5.6 0.21 10.8 5.6 1.4 1 0 0 1 1 1 0 HindIII restriction endonuclease HlyD_2 PF12700.7 KUM60830.1 - 0.45 9.2 3.1 0.65 8.7 3.1 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF87 PF01935.17 KUM60830.1 - 0.81 9.7 0.0 0.81 9.7 0.0 3.1 3 1 0 3 3 3 0 Helicase HerA, central domain DUF1460 PF07313.12 KUM60830.1 - 1.1 8.6 4.1 0.54 9.6 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1460) Kinesin_assoc PF16183.5 KUM60830.1 - 2.7 8.1 5.9 2.1 8.5 3.1 2.2 2 0 0 2 2 2 0 Kinesin-associated TBCC_N PF16752.5 KUM60830.1 - 3.5 8.1 11.3 21 5.6 11.3 2.3 1 1 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain V_ATPase_I PF01496.19 KUM60830.1 - 3.8 5.3 9.0 6.6 4.5 9.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_M32 PF02074.15 KUM60830.1 - 4.3 6.0 13.0 1.3 7.7 7.7 2.1 2 0 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase adh_short PF00106.25 KUM60831.1 - 1.9e-23 83.0 0.0 2.3e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM60831.1 - 1.2e-21 77.4 0.0 1.4e-21 77.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM60831.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 KUM60831.1 - 0.013 14.9 0.0 0.027 13.9 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1275 PF06912.11 KUM60833.1 - 1.9e-46 158.4 10.9 2.2e-46 158.2 10.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Ank_2 PF12796.7 KUM60834.1 - 2e-15 57.2 0.0 8.9e-08 32.6 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KUM60834.1 - 1.8e-11 43.2 0.1 0.028 14.9 0.0 5.0 3 1 1 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KUM60834.1 - 1.3e-07 32.0 0.0 0.029 14.9 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM60834.1 - 6.3e-07 29.6 0.1 0.32 11.4 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KUM60834.1 - 3e-06 27.4 0.1 0.68 10.5 0.0 4.5 3 1 1 4 4 4 2 Ankyrin repeat Ion_trans_2 PF07885.16 KUM60835.1 - 1.5e-27 95.4 19.8 1.7e-16 60.0 5.6 3.7 4 0 0 4 4 4 2 Ion channel Ion_trans PF00520.31 KUM60835.1 - 0.0023 17.2 0.8 0.0023 17.2 0.8 3.5 3 1 0 3 3 3 1 Ion transport protein DUF4083 PF13314.6 KUM60835.1 - 6.7 6.7 8.7 4.5 7.3 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) GXWXG PF14231.6 KUM60836.1 - 2.1e-20 72.5 0.3 6.9e-20 70.9 0.1 1.9 2 0 0 2 2 2 1 GXWXG protein DUF4334 PF14232.6 KUM60836.1 - 2.3e-18 65.9 0.0 3.3e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4334) Fungal_trans_2 PF11951.8 KUM60837.1 - 1.6e-50 172.1 0.3 2.9e-50 171.2 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60837.1 - 2.3e-05 24.4 5.9 4.9e-05 23.4 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCIP PF13862.6 KUM60840.1 - 2.4e-74 249.6 0.1 3.1e-74 249.2 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Sad1_UNC PF07738.13 KUM60841.1 - 7.9e-11 42.1 0.0 3.5e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal CBS PF00571.28 KUM60842.1 - 9.3e-21 74.0 6.3 3.6e-09 36.9 0.1 3.8 4 0 0 4 4 4 3 CBS domain RhoGAP PF00620.27 KUM60843.1 - 2.9e-05 23.9 0.0 4.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Mannosyl_trans3 PF11051.8 KUM60844.1 - 6.6e-59 199.5 0.0 2.3e-37 128.9 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative DHHC PF01529.20 KUM60844.1 - 0.17 12.0 0.1 0.88 9.7 0.0 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF3177 PF11375.8 KUM60846.1 - 0.03 14.1 0.2 0.039 13.7 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3177) NAD_binding_6 PF08030.12 KUM60847.1 - 5.7e-26 91.5 0.0 7.3e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KUM60847.1 - 2.4e-10 40.5 0.0 5.8e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KUM60847.1 - 0.029 15.0 0.0 0.16 12.6 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Apc13p PF05839.11 KUM60848.1 - 2.8e-19 69.1 0.1 1.5e-14 54.0 0.0 2.3 2 0 0 2 2 2 2 Apc13p protein IF-2B PF01008.17 KUM60849.1 - 7e-75 251.8 0.0 8.9e-75 251.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family CRAL_TRIO PF00650.20 KUM60850.1 - 5.7e-39 133.4 0.0 8e-39 132.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KUM60850.1 - 4e-16 58.9 0.2 7.9e-16 58.0 0.2 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KUM60850.1 - 0.00079 19.6 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.10 KUM60851.1 - 1.2e-78 264.5 0.0 1.5e-78 264.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KUM60851.1 - 5.1e-36 124.0 0.0 7.5e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B WD40 PF00400.32 KUM60853.1 - 7.8e-29 99.3 11.4 8.8e-06 26.4 1.3 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 KUM60853.1 - 9e-09 34.5 0.8 0.047 12.3 0.1 4.8 3 1 2 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KUM60853.1 - 9.3e-06 25.9 0.1 0.19 12.1 0.0 4.2 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Seryl_tRNA_N PF02403.22 KUM60853.1 - 0.051 13.8 0.5 0.13 12.5 0.1 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 KUM60853.1 - 0.3 11.6 4.0 0.59 10.7 4.0 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region SRR1 PF07985.12 KUM60854.1 - 1.9e-11 43.8 0.0 2.6e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 SRR1 SnoaL PF07366.12 KUM60856.1 - 3.6e-30 104.4 0.0 4e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KUM60856.1 - 1.4e-15 57.7 0.0 1.6e-15 57.6 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain Aldo_ket_red PF00248.21 KUM60857.1 - 6.3e-43 147.0 0.0 8.7e-41 140.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Ribosomal_S17e PF00833.18 KUM60858.1 - 8.2e-61 203.3 0.8 1e-60 203.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal S17 Mit_ribos_Mrp51 PF11709.8 KUM60859.1 - 7.4e-109 364.7 0.1 8.7e-109 364.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Epimerase PF01370.21 KUM60860.1 - 5.9e-19 68.5 0.0 7.9e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KUM60860.1 - 7.5e-16 57.9 0.0 9.8e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KUM60860.1 - 6.3e-09 35.4 0.0 3.9e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KUM60860.1 - 1.1e-08 34.9 0.0 2.2e-08 33.9 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KUM60860.1 - 2.2e-06 27.7 0.0 3.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KUM60860.1 - 0.00013 21.2 0.0 0.0002 20.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KUM60860.1 - 0.0002 20.9 0.0 0.00038 20.0 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM60860.1 - 0.00074 19.5 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KUM60860.1 - 0.0018 17.9 0.2 0.0067 16.0 0.2 2.0 2 1 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.6 KUM60860.1 - 0.0049 16.5 0.0 0.0093 15.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 KUM60860.1 - 0.0058 16.9 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KUM60860.1 - 0.046 14.2 0.1 0.13 12.7 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain F-box-like PF12937.7 KUM60861.1 - 1.9e-05 24.4 0.1 4.8e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like FAT PF02259.23 KUM60862.1 - 2.9e-133 444.4 0.4 2.9e-133 444.4 0.4 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KUM60862.1 - 4.3e-70 236.4 0.0 8.5e-70 235.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KUM60862.1 - 5.3e-66 221.5 4.6 6.2e-61 205.0 1.3 4.8 4 1 1 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KUM60862.1 - 2.1e-41 140.4 0.1 2.1e-41 140.4 0.1 4.2 5 0 0 5 5 3 1 FKBP12-rapamycin binding domain FATC PF02260.20 KUM60862.1 - 8e-16 57.6 1.0 1.9e-15 56.4 1.0 1.7 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.6 KUM60862.1 - 7.3e-15 55.1 10.9 0.012 16.1 0.0 11.3 11 2 0 11 11 11 2 HEAT-like repeat HEAT_2 PF13646.6 KUM60862.1 - 2.6e-13 50.1 10.3 0.0041 17.5 0.0 9.2 8 2 1 9 9 9 3 HEAT repeats HEAT PF02985.22 KUM60862.1 - 1.2e-09 37.6 23.1 0.0041 17.2 0.0 11.7 14 0 0 14 14 11 2 HEAT repeat Adaptin_N PF01602.20 KUM60862.1 - 7.3e-07 28.1 6.2 0.01 14.4 0.2 5.6 3 2 3 6 6 6 3 Adaptin N terminal region Tti2 PF10521.9 KUM60862.1 - 0.0022 17.6 1.5 7.4 6.0 0.0 5.0 3 1 2 5 5 5 1 Tti2 family CLASP_N PF12348.8 KUM60862.1 - 0.0023 17.5 1.1 1.4 8.5 0.0 4.7 5 0 0 5 5 5 1 CLASP N terminal UME PF08064.13 KUM60862.1 - 0.0036 17.2 3.9 7.2 6.6 0.0 6.6 6 1 1 7 7 7 1 UME (NUC010) domain MMS19_C PF12460.8 KUM60862.1 - 0.0063 15.7 7.2 0.11 11.6 0.0 4.1 4 1 0 4 4 4 1 RNAPII transcription regulator C-terminal Sec7_N PF12783.7 KUM60862.1 - 0.072 13.0 0.1 2.8 7.8 0.0 3.6 4 0 0 4 4 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_14 PF13428.6 KUM60862.1 - 0.12 13.2 3.8 1.2 10.1 0.1 4.4 2 1 1 3 3 2 0 Tetratricopeptide repeat CWC25 PF12542.8 KUM60863.1 - 8.2e-21 74.8 0.0 8.2e-21 74.8 0.0 3.6 3 2 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KUM60863.1 - 1.2e-14 54.2 9.9 1.2e-14 54.2 9.9 4.9 3 1 2 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF4246 PF14033.6 KUM60865.1 - 6e-28 98.2 0.1 8e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) KfrA_N PF11740.8 KUM60865.1 - 0.079 13.6 3.7 0.11 13.2 3.7 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term RPAP2_Rtr1 PF04181.13 KUM60866.1 - 1.1e-19 70.5 0.0 2.1e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family ECH_1 PF00378.20 KUM60868.1 - 6.1e-53 179.7 0.0 7.7e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KUM60868.1 - 3.6e-26 92.5 0.1 1e-22 81.1 0.1 2.4 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DoxD PF04173.13 KUM60868.1 - 0.045 13.7 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 TQO small subunit DoxD MFS_1 PF07690.16 KUM60869.1 - 2.4e-21 76.1 44.4 2.4e-21 76.1 44.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM60869.1 - 1.3e-05 23.9 27.3 1.3e-05 23.8 26.2 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMEM208_SND2 PF05620.11 KUM60869.1 - 0.86 9.4 9.1 1.4 8.6 4.5 2.7 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 ABC_membrane PF00664.23 KUM60870.1 - 7.2e-90 301.3 26.5 3.6e-52 177.7 5.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KUM60870.1 - 2e-62 209.8 0.1 8.6e-31 107.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KUM60870.1 - 9.2e-17 61.2 0.7 8.6e-06 25.3 0.0 4.4 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KUM60870.1 - 1.2e-08 34.6 0.3 0.0024 17.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KUM60870.1 - 7.5e-07 29.5 3.1 0.12 12.6 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KUM60870.1 - 2.3e-06 28.1 2.8 0.034 14.5 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 KUM60870.1 - 2.6e-06 27.3 1.9 0.03 14.1 0.0 3.9 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KUM60870.1 - 7.8e-06 25.9 0.0 0.036 14.0 0.0 3.1 3 0 0 3 3 2 2 RsgA GTPase APS_kinase PF01583.20 KUM60870.1 - 1.1e-05 25.4 0.2 0.0057 16.6 0.1 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase DUF87 PF01935.17 KUM60870.1 - 1.2e-05 25.5 0.3 0.031 14.4 0.0 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_23 PF13476.6 KUM60870.1 - 0.00017 22.2 0.2 0.85 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KUM60870.1 - 0.00025 20.0 2.4 0.012 14.4 0.0 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA PF00004.29 KUM60870.1 - 0.00075 19.9 1.8 6.6 7.2 0.2 4.2 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KUM60870.1 - 0.00088 18.6 1.2 0.58 9.4 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA_5 PF07728.14 KUM60870.1 - 0.0013 18.8 0.0 3.1 7.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KUM60870.1 - 0.0015 18.2 0.4 1.2 8.7 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 KUM60870.1 - 0.0018 18.9 0.0 3.3 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KUM60870.1 - 0.0019 18.1 0.2 0.18 11.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KUM60870.1 - 0.004 17.3 0.1 3.8 7.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF3987 PF13148.6 KUM60870.1 - 0.012 14.7 0.3 2.4 7.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) NB-ARC PF00931.22 KUM60870.1 - 0.018 14.2 0.1 2.7 7.1 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain AAA_7 PF12775.7 KUM60870.1 - 0.021 14.4 0.1 8.2 5.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 KUM60870.1 - 0.024 14.9 0.3 8.7 6.7 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KUM60870.1 - 0.027 14.6 0.1 6.8 6.8 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase DEAD PF00270.29 KUM60870.1 - 0.031 14.1 1.2 0.32 10.7 0.1 3.3 4 1 0 4 4 3 0 DEAD/DEAH box helicase KdpD PF02702.17 KUM60870.1 - 0.033 13.6 0.0 2 7.8 0.0 2.4 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain Cad PF03596.13 KUM60870.1 - 0.067 13.1 4.2 0.29 11.0 0.7 2.8 2 0 0 2 2 2 0 Cadmium resistance transporter AAA_24 PF13479.6 KUM60870.1 - 0.075 12.7 0.0 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KUM60870.1 - 0.11 12.9 0.0 26 5.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KUM60870.1 - 0.2 11.3 0.3 12 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Acetyltransf_8 PF13523.6 KUM60871.1 - 1.1e-39 135.4 0.2 1.5e-39 134.9 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1749 PF08538.10 KUM60872.1 - 3.4e-98 328.4 0.0 4.2e-98 328.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.20 KUM60872.1 - 3.3e-05 23.7 0.9 0.00028 20.6 0.2 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF900 PF05990.12 KUM60872.1 - 0.0071 15.9 0.0 0.022 14.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 KUM60872.1 - 0.015 14.6 0.0 0.035 13.4 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KUM60872.1 - 0.029 14.1 0.0 0.087 12.5 0.0 1.8 1 1 0 1 1 1 0 PGAP1-like protein Condensation PF00668.20 KUM60873.1 - 1.4e-72 244.8 0.0 2.3e-37 128.8 0.0 2.8 3 0 0 3 3 3 2 Condensation domain AMP-binding PF00501.28 KUM60873.1 - 1.9e-72 244.2 0.0 8.1e-68 228.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 KUM60873.1 - 2.4e-27 95.1 0.2 2.5e-12 47.0 0.1 3.4 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM60873.1 - 0.0015 19.5 0.1 3.7 8.6 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain SH3_9 PF14604.6 KUM60874.1 - 4.2e-08 32.9 0.3 9.4e-08 31.8 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KUM60874.1 - 2.1e-06 27.2 0.1 4.3e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KUM60874.1 - 2.2e-05 24.1 0.0 4.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain eIF3_subunit PF08597.10 KUM60874.1 - 2.2 8.1 19.7 0.12 12.3 5.4 2.8 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit CDC45 PF02724.14 KUM60874.1 - 4.3 5.5 6.3 7.4 4.7 6.3 1.3 1 0 0 1 1 1 0 CDC45-like protein FAA_hydrolase PF01557.18 KUM60877.1 - 8.5e-62 208.7 0.0 1.3e-61 208.0 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Pkinase PF00069.25 KUM60880.1 - 7.6e-63 212.3 0.0 1e-62 211.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM60880.1 - 1.1e-26 93.7 0.0 1.8e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KUM60880.1 - 0.08 11.9 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KUM60880.1 - 0.099 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KUM60880.1 - 0.12 11.7 0.0 0.4 9.9 0.0 1.8 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KUM60880.1 - 0.2 11.6 0.1 0.2 11.6 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KUM60880.1 - 0.67 8.7 2.5 1.5 7.5 2.6 1.6 1 1 0 1 1 1 0 Fungal protein kinase HMA PF00403.26 KUM60881.1 - 2.6e-13 50.2 0.0 6.3e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 KUM60881.1 - 2.7e-08 34.1 0.0 3.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) AMP-binding PF00501.28 KUM60883.1 - 1.5e-89 300.5 0.0 2.2e-89 300.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM60883.1 - 0.00068 20.6 0.0 0.002 19.0 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CdhD PF03599.16 KUM60883.1 - 0.13 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit NDT80_PhoG PF05224.12 KUM60885.1 - 1.4e-36 126.5 0.0 2.5e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family HSP70 PF00012.20 KUM60886.1 - 2.2e-262 871.6 19.0 2.6e-262 871.4 19.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KUM60886.1 - 1.7e-14 53.4 6.1 2e-13 49.9 2.6 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KUM60886.1 - 0.0026 17.5 0.1 0.0068 16.2 0.1 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain THUMP PF02926.17 KUM60886.1 - 0.15 12.1 1.6 5 7.2 1.5 2.6 2 0 0 2 2 2 0 THUMP domain FtsA PF14450.6 KUM60886.1 - 2.7 8.5 12.9 1.9 8.9 0.3 4.3 3 3 0 3 3 3 0 Cell division protein FtsA Methyltransf_16 PF10294.9 KUM60887.1 - 5.7e-07 29.4 0.0 0.013 15.3 0.0 2.9 2 1 0 2 2 2 2 Lysine methyltransferase DUF3349 PF11829.8 KUM60888.1 - 0.092 13.5 0.1 0.23 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) DUF1682 PF07946.14 KUM60888.1 - 7.2 5.7 7.3 11 5.1 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) zf-H2C2_2 PF13465.6 KUM60889.1 - 1.7e-06 28.2 3.3 1.7e-06 28.2 3.3 3.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 KUM60889.1 - 2e-05 24.7 16.7 0.0007 19.9 4.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM60889.1 - 2.1e-05 25.0 19.7 0.0012 19.5 3.5 3.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KUM60889.1 - 6e-05 22.9 1.4 6e-05 22.9 1.4 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KUM60889.1 - 0.025 14.9 0.3 0.025 14.9 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KUM60889.1 - 0.057 13.7 4.9 0.16 12.3 4.9 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KUM60889.1 - 0.064 13.7 1.2 0.064 13.7 1.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 KUM60889.1 - 2.9 7.6 6.7 0.23 11.2 0.5 2.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain FAD_binding_3 PF01494.19 KUM60890.1 - 1.2e-34 120.2 0.0 3.3e-32 112.1 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 KUM60890.1 - 0.035 14.3 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 KUM60890.1 - 0.18 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Glyoxalase PF00903.25 KUM60891.1 - 0.096 12.9 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KUM60892.1 - 4.3e-07 30.2 2.2 8.3e-07 29.2 2.2 1.5 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short PF00106.25 KUM60894.1 - 9.5e-22 77.4 0.0 2.6e-19 69.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM60894.1 - 4.2e-13 49.4 0.0 1.5e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM60894.1 - 3.2e-11 43.5 0.0 5.5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KUM60894.1 - 0.00095 18.4 0.0 0.0013 18.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KUM60894.1 - 0.0033 16.9 0.0 0.0053 16.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KUM60894.1 - 0.015 15.6 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 KUM60894.1 - 0.029 15.1 0.1 0.048 14.4 0.1 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Shikimate_DH PF01488.20 KUM60894.1 - 0.029 14.4 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KUM60894.1 - 0.069 12.5 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Transp_cyt_pur PF02133.15 KUM60895.1 - 8.5e-44 150.0 38.3 1e-43 149.7 38.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Rer1 PF03248.13 KUM60895.1 - 4.2 7.1 7.0 0.3 10.8 1.4 2.1 2 0 0 2 2 2 0 Rer1 family MFS_1 PF07690.16 KUM60896.1 - 7.5e-12 44.8 14.9 7.5e-12 44.8 14.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily GerA PF03323.13 KUM60896.1 - 0.65 8.4 2.2 0.97 7.8 2.2 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein eIF3g PF12353.8 KUM60897.1 - 1.5e-43 148.1 2.5 2.2e-43 147.6 2.5 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KUM60897.1 - 1e-14 54.1 0.0 1.6e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 KUM60897.1 - 0.029 14.7 0.8 0.057 13.7 0.2 1.7 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Ank_2 PF12796.7 KUM60898.1 - 3.1e-40 136.6 3.7 6e-10 39.6 0.0 8.4 5 2 4 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM60898.1 - 1.1e-26 92.9 6.5 1.8e-06 28.4 0.0 10.5 6 4 5 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM60898.1 - 8.1e-24 81.1 11.3 0.18 12.4 0.0 14.2 15 0 0 15 15 15 4 Ankyrin repeat Ank_5 PF13857.6 KUM60898.1 - 3.1e-14 52.8 8.2 0.24 11.8 0.0 10.4 11 1 1 12 12 12 3 Ankyrin repeats (many copies) Clr5 PF14420.6 KUM60898.1 - 1.1e-13 51.2 0.1 2.7e-13 49.9 0.1 1.8 2 0 0 2 2 2 1 Clr5 domain Ank PF00023.30 KUM60898.1 - 2.4e-10 40.4 17.0 2 9.0 0.1 10.5 11 0 0 11 11 11 3 Ankyrin repeat DUF3447 PF11929.8 KUM60898.1 - 0.0061 16.5 0.0 68 3.5 0.0 4.7 4 1 0 4 4 4 0 Domain of unknown function (DUF3447) DHquinase_II PF01220.19 KUM60898.1 - 0.04 13.6 0.2 0.12 12.0 0.2 1.8 1 0 0 1 1 1 0 Dehydroquinase class II ADH_N PF08240.12 KUM60899.1 - 2e-16 59.8 0.6 7.2e-16 58.0 0.6 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM60899.1 - 5.3e-08 32.9 0.1 1.2e-06 28.6 0.1 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KUM60899.1 - 0.06 12.6 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 KUM60899.1 - 0.11 11.9 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 KUM60899.1 - 0.22 10.2 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein adh_short PF00106.25 KUM60900.1 - 3.8e-23 82.0 0.0 2.1e-22 79.5 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM60900.1 - 4.8e-17 62.3 0.0 1.2e-16 61.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM60900.1 - 7.8e-05 22.7 0.1 0.00015 21.7 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM60900.1 - 0.025 14.1 0.0 0.069 12.6 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KUM60900.1 - 0.033 14.1 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding PDEase_I PF00233.19 KUM60901.1 - 1.1e-70 238.1 0.0 2.9e-70 236.7 0.0 1.7 1 1 1 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase G-gamma PF00631.22 KUM60902.1 - 1.2e-23 82.9 0.0 1.4e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 GGL domain PCI PF01399.27 KUM60904.1 - 1.3e-09 38.5 3.8 2.9e-09 37.4 0.0 3.3 3 0 0 3 3 3 1 PCI domain XdhC_C PF13478.6 KUM60904.1 - 0.98 9.9 4.0 4 8.0 4.0 2.1 1 0 0 1 1 1 0 XdhC Rossmann domain SOBP PF15279.6 KUM60904.1 - 1.9 9.0 16.2 0.12 12.9 8.6 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein ADH_zinc_N PF00107.26 KUM60905.1 - 2.2e-22 79.4 0.1 3.6e-22 78.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM60905.1 - 5.9e-17 63.0 0.0 9.4e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM60905.1 - 8.1e-09 35.3 0.0 1.9e-07 30.9 0.0 2.2 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain zf-HC5HC2H_2 PF13832.6 KUM60906.1 - 7.8e-22 77.5 0.2 7.8e-22 77.5 0.2 4.3 4 0 0 4 4 4 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KUM60906.1 - 3.1e-20 72.2 0.6 3.1e-20 72.2 0.6 4.4 4 1 0 4 4 4 2 PHD-like zinc-binding domain BAH PF01426.18 KUM60906.1 - 3.2e-15 56.1 0.0 6.6e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 KUM60906.1 - 5.2e-11 42.3 22.0 3.9e-07 29.8 7.8 5.1 6 0 0 6 6 6 2 PHD-finger PHD_2 PF13831.6 KUM60906.1 - 9.1e-09 34.7 4.7 9.1e-09 34.7 4.7 4.8 5 0 0 5 5 5 1 PHD-finger Myb_DNA-binding PF00249.31 KUM60906.1 - 5.6e-05 23.3 1.5 0.00019 21.6 0.1 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain FYVE_2 PF02318.16 KUM60906.1 - 0.0091 16.2 3.8 0.0091 16.2 3.8 4.1 5 0 0 5 5 3 1 FYVE-type zinc finger C1_2 PF03107.16 KUM60906.1 - 0.023 15.0 0.7 0.023 15.0 0.7 6.0 6 0 0 6 6 6 0 C1 domain ArfGap PF01412.18 KUM60906.1 - 1.1 9.3 6.7 12 6.0 0.0 3.7 4 0 0 4 4 4 0 Putative GTPase activating protein for Arf GATA PF00320.27 KUM60906.1 - 2.3 7.9 15.3 2.1 8.0 1.1 4.9 4 0 0 4 4 4 0 GATA zinc finger ELM2 PF01448.24 KUM60906.1 - 3.5 8.4 6.0 17 6.2 1.5 3.8 3 1 0 3 3 3 0 ELM2 domain Peptidase_M35 PF02102.15 KUM60907.1 - 2.5e-29 102.3 6.3 2.9e-29 102.1 6.3 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KUM60907.1 - 3.3e-23 82.8 1.1 4.9e-23 82.3 1.1 1.2 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Osteoregulin PF07175.11 KUM60907.1 - 0.0084 16.3 0.1 0.013 15.8 0.1 1.2 1 0 0 1 1 1 1 Osteoregulin NanE PF04131.14 KUM60908.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase 2Fe-2S_thioredx PF01257.19 KUM60909.1 - 7.1e-59 197.8 0.1 1e-58 197.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin RSN1_7TM PF02714.15 KUM60910.1 - 2.5e-88 296.0 30.6 2.5e-88 296.0 30.6 1.8 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KUM60910.1 - 7.7e-48 162.2 0.5 7.7e-48 162.2 0.5 3.4 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KUM60910.1 - 3.1e-31 109.0 0.7 1.3e-17 64.6 0.0 2.7 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KUM60910.1 - 2.8e-13 49.9 0.2 8.4e-13 48.3 0.0 1.9 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter MCM PF00493.23 KUM60911.1 - 4.6e-102 339.9 0.0 6.5e-102 339.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KUM60911.1 - 2.8e-39 133.8 0.8 6.1e-39 132.8 0.8 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KUM60911.1 - 7.9e-29 99.9 1.9 1.6e-28 98.9 1.9 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KUM60911.1 - 5.2e-14 52.7 0.1 2.1e-13 50.7 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KUM60911.1 - 7.5e-06 25.5 0.0 0.0002 20.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KUM60911.1 - 1.4e-05 25.2 0.0 3.4e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KUM60911.1 - 0.0026 17.6 0.0 0.0071 16.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KUM60911.1 - 0.17 11.5 0.3 6.4 6.5 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain Band_7 PF01145.25 KUM60912.1 - 1.4e-23 83.8 3.7 2.2e-23 83.2 3.7 1.3 1 1 0 1 1 1 1 SPFH domain / Band 7 family DEAD PF00270.29 KUM60914.1 - 1.1e-16 61.1 0.0 3.1e-16 59.6 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KUM60914.1 - 3.6e-08 33.6 0.0 6.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KUM60914.1 - 6e-08 33.0 0.0 2e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4332 PF14229.6 KUM60914.1 - 0.0051 17.1 0.1 0.02 15.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4332) AAA_22 PF13401.6 KUM60914.1 - 0.013 15.8 0.0 0.1 12.9 0.0 2.5 1 1 0 1 1 1 0 AAA domain Sigma70_r4 PF04545.16 KUM60914.1 - 0.058 12.9 0.0 0.31 10.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 DUF5580 PF17743.1 KUM60915.1 - 0.53 8.8 5.9 0.63 8.5 5.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) VTC PF09359.10 KUM60916.1 - 6.2e-100 334.1 0.4 1.1e-99 333.3 0.4 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KUM60916.1 - 1.1e-12 48.2 7.0 2.3e-12 47.2 4.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KUM60916.1 - 7.2e-11 42.6 15.8 5.4e-05 23.3 0.1 3.9 3 1 1 4 4 4 3 SPX domain RexA PF15969.5 KUM60916.1 - 0.066 12.8 0.2 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 Intracellular sensor of Lambda phage, Abi component Fungal_trans PF04082.18 KUM60917.1 - 2.3e-25 89.1 0.2 3.7e-25 88.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60917.1 - 0.00046 20.2 11.3 0.00081 19.5 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Corona_M PF01635.18 KUM60917.1 - 0.16 11.2 0.8 0.29 10.4 0.8 1.3 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein SNF2_N PF00176.23 KUM60918.1 - 7.4e-19 67.7 0.0 2.5e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 KUM60918.1 - 2e-13 50.4 0.0 6.2e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 KUM60918.1 - 0.00036 20.8 0.0 0.0057 17.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KUM60918.1 - 0.0004 20.3 7.9 0.0004 20.3 7.9 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KUM60918.1 - 0.0073 16.3 14.8 0.12 12.5 6.1 2.6 2 0 0 2 2 2 2 RING-type zinc-finger ResIII PF04851.15 KUM60918.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 KUM60918.1 - 0.12 12.2 14.5 0.39 10.6 5.8 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM60918.1 - 5.6 6.9 22.6 0.057 13.3 6.1 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KUM60918.1 - 7.4 7.0 24.5 0.3 11.4 7.2 2.8 2 0 0 2 2 2 0 Ring finger domain CSTF2_hinge PF14327.6 KUM60919.1 - 2.4e-31 108.0 2.3 2.4e-31 108.0 2.3 2.2 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KUM60919.1 - 2.5e-19 68.8 0.0 4.7e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KUM60919.1 - 1.6e-17 62.8 14.3 1e-16 60.2 10.5 3.1 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KUM60919.1 - 0.0087 16.2 0.1 0.77 9.9 0.0 2.6 1 1 1 2 2 2 1 RNA recognition motif Spo7_2_N PF15407.6 KUM60919.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_5 PF13893.6 KUM60919.1 - 0.053 13.1 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KUM60919.1 - 0.071 13.0 0.0 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KUM60919.1 - 0.1 12.4 0.0 4.2 7.1 0.0 2.2 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain AMP-binding PF00501.28 KUM60920.1 - 2.1e-274 909.6 0.0 1.2e-67 228.4 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 KUM60920.1 - 2.4e-139 464.9 0.0 1.3e-41 142.8 0.0 5.7 4 2 1 5 5 5 5 Condensation domain PP-binding PF00550.25 KUM60920.1 - 3.3e-43 145.9 6.4 2.8e-10 40.4 0.2 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM60920.1 - 1.4e-07 32.4 0.0 0.7 10.9 0.0 4.9 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain MG4 PF17789.1 KUM60922.1 - 0.067 13.3 0.0 0.12 12.6 0.0 1.4 1 1 0 1 1 1 0 Macroglobulin domain MG4 Acyltransferase PF01553.21 KUM60923.1 - 4.8e-18 65.1 0.0 1.3e-17 63.7 0.0 1.7 1 1 0 1 1 1 1 Acyltransferase L31 PF09784.9 KUM60924.1 - 7.3e-46 154.8 1.3 8.1e-46 154.6 1.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 DEAD PF00270.29 KUM60925.1 - 1.7e-42 145.1 0.9 3.1e-42 144.3 0.9 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM60925.1 - 3.3e-32 111.1 0.9 1.1e-29 103.1 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KUM60925.1 - 2.5e-08 34.1 1.0 3.2e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 KUM60925.1 - 0.032 12.5 0.2 0.047 12.0 0.2 1.2 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 KUM60925.1 - 0.049 13.5 6.5 0.12 12.3 6.5 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CMS1 PF14617.6 KUM60925.1 - 1.2 8.4 7.1 3.2 7.0 0.0 3.2 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit CCDC106 PF15794.5 KUM60925.1 - 2.3 7.9 8.6 0.21 11.3 3.7 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 FAD_binding_4 PF01565.23 KUM60927.1 - 5.3e-20 71.6 0.5 1e-19 70.7 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KUM60927.1 - 0.0051 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Laminin_II PF06009.12 KUM60928.1 - 0.067 13.2 1.7 3.2 7.8 0.0 2.7 2 1 0 2 2 2 0 Laminin Domain II adh_short PF00106.25 KUM60929.1 - 2.9e-17 62.8 0.0 3.9e-15 55.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM60929.1 - 5.4e-08 32.7 0.0 2.8e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM60929.1 - 0.0019 18.1 0.0 0.0043 17.0 0.0 1.5 2 0 0 2 2 2 1 KR domain Deltaretro_Tax PF05599.11 KUM60929.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Deltaretrovirus Tax protein tRNA-synt_1d PF00750.19 KUM60931.1 - 5.9e-99 331.3 7.4 1.8e-97 326.4 7.4 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KUM60931.1 - 3.9e-27 94.8 0.2 3.9e-27 94.8 0.2 1.8 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KUM60931.1 - 2.7e-09 37.5 0.2 3.9e-08 33.8 0.0 2.4 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain ABC_tran PF00005.27 KUM60934.1 - 1.8e-27 96.6 0.1 2.9e-27 95.8 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KUM60934.1 - 7.8e-27 94.1 28.8 1.4e-26 93.2 28.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_16 PF13191.6 KUM60934.1 - 8.5e-07 29.5 0.1 1.4e-06 28.8 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KUM60934.1 - 1.6e-06 28.1 0.0 6.6e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KUM60934.1 - 4.6e-05 23.6 0.0 8.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KUM60934.1 - 0.00013 21.6 0.0 0.00033 20.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KUM60934.1 - 0.00018 21.8 0.0 0.00034 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KUM60934.1 - 0.00025 20.9 0.7 0.37 10.5 0.0 2.7 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KUM60934.1 - 0.0007 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KUM60934.1 - 0.0013 19.0 0.0 0.012 15.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KUM60934.1 - 0.0017 18.9 0.0 0.0041 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KUM60934.1 - 0.002 18.6 0.0 0.0084 16.5 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KUM60934.1 - 0.0029 17.4 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 KUM60934.1 - 0.0038 17.0 0.0 0.0081 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KUM60934.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.6 KUM60934.1 - 0.017 13.8 0.0 0.051 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KUM60934.1 - 0.019 15.4 0.0 0.052 13.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KUM60934.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 KUM60934.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KUM60934.1 - 0.03 14.4 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 KUM60934.1 - 0.034 14.1 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KUM60934.1 - 0.039 14.0 0.0 0.087 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KUM60934.1 - 0.045 13.8 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TsaE PF02367.17 KUM60934.1 - 0.064 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KUM60934.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KUM60934.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_35 PF14516.6 KUM60934.1 - 0.081 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain PNTB_4TM PF12769.7 KUM60934.1 - 0.084 13.4 2.1 0.13 12.7 0.7 2.1 2 0 0 2 2 1 0 4TM region of pyridine nucleotide transhydrogenase, mitoch MeaB PF03308.16 KUM60934.1 - 0.097 11.6 0.2 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 KUM60934.1 - 0.11 11.6 0.1 0.33 10.1 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 KUM60934.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.14 KUM60934.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.6 KUM60934.1 - 0.16 12.5 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KUM60934.1 - 0.17 11.5 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FAD_binding_6 PF00970.24 KUM60936.1 - 8.7e-33 112.6 0.0 1.3e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KUM60936.1 - 1.4e-27 96.5 0.0 2.2e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KUM60936.1 - 2.1e-07 31.2 0.0 9.1e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KUM60936.1 - 0.021 15.1 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF3605 PF12239.8 KUM60937.1 - 3.3e-60 202.9 0.0 3.8e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) MgtE_N PF03448.17 KUM60938.1 - 0.13 12.9 0.0 0.22 12.2 0.0 1.3 1 0 0 1 1 1 0 MgtE intracellular N domain FixS PF03597.15 KUM60939.1 - 0.13 12.0 2.4 0.26 11.0 2.4 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Spherulin4 PF12138.8 KUM60940.1 - 5.6e-50 170.2 0.2 6.5e-50 170.0 0.2 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 E1_dh PF00676.20 KUM60941.1 - 1.3e-89 300.1 0.0 1.6e-89 299.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KUM60941.1 - 1.8e-05 24.5 0.1 0.00045 20.0 0.0 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ish1 PF10281.9 KUM60941.1 - 0.0062 16.8 0.2 0.011 16.0 0.2 1.4 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein XFP_N PF09364.10 KUM60941.1 - 0.032 13.0 0.0 0.053 12.3 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain DXP_synthase_N PF13292.6 KUM60941.1 - 0.088 12.0 0.0 0.34 10.1 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase NUDIX PF00293.28 KUM60942.1 - 8.6e-09 35.5 0.2 1e-08 35.3 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain Y_phosphatase3 PF13350.6 KUM60943.1 - 1.2e-53 182.5 0.0 1.4e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KUM60943.1 - 1.9e-05 24.4 0.0 2.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KUM60943.1 - 0.00024 20.7 0.0 0.00037 20.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KUM60943.1 - 0.031 14.4 0.0 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Myotub-related PF06602.14 KUM60943.1 - 0.049 12.6 0.0 0.067 12.1 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Ig_mannosidase PF17753.1 KUM60944.1 - 2e-22 78.7 0.0 4.8e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 KUM60944.1 - 4.9e-15 55.9 0.7 1.4e-14 54.4 0.2 2.1 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KUM60944.1 - 7.4e-08 33.0 0.1 2.4e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ig_GlcNase PF18368.1 KUM60944.1 - 0.0064 16.6 0.0 0.032 14.4 0.0 2.1 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain DUF4299 PF14132.6 KUM60944.1 - 0.083 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) NAGidase PF07555.13 KUM60945.1 - 5.9e-102 340.9 0.6 7.7e-102 340.6 0.6 1.1 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase Glyco_hydro_20b PF02838.15 KUM60945.1 - 3e-22 79.7 0.1 5.6e-22 78.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_67N PF03648.14 KUM60945.1 - 0.00067 19.9 0.1 0.0016 18.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus AnmK PF03702.14 KUM60946.1 - 1.8e-85 287.2 0.0 2.1e-85 287.0 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Zn_clus PF00172.18 KUM60947.1 - 8.7e-06 25.8 8.9 1.3e-05 25.2 8.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KAR9 PF08580.10 KUM60947.1 - 0.21 10.1 0.6 0.24 9.9 0.6 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Fungal_trans PF04082.18 KUM60948.1 - 1.1e-07 31.2 0.0 1.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain 4HBT PF03061.22 KUM60949.1 - 5.9e-09 36.2 0.0 1.2e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DNA_pol_phi PF04931.13 KUM60951.1 - 0.067 11.3 42.9 0.083 11.0 42.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi RNA_polI_A34 PF08208.11 KUM60951.1 - 4.3 7.4 8.6 7.5 6.6 8.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Tankyrase_bdg_C PF15327.6 KUM60951.1 - 8.2 6.9 6.4 15 6.0 6.4 1.5 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain CTP_transf_like PF01467.26 KUM60952.1 - 4.5e-25 88.5 0.0 6.1e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like SIS PF01380.22 KUM60953.1 - 1.8e-14 53.7 0.0 2.3e-13 50.1 0.0 2.2 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.6 KUM60953.1 - 7.6e-07 29.2 0.0 0.00022 21.2 0.1 2.3 1 1 1 2 2 2 2 SIS domain Usp PF00582.26 KUM60953.1 - 0.013 16.0 0.8 0.096 13.2 0.2 2.3 2 0 0 2 2 2 0 Universal stress protein family DUF4392 PF14336.6 KUM60953.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) HECT PF00632.25 KUM60955.1 - 4.7e-76 256.2 0.0 8.3e-76 255.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.22 KUM60955.1 - 0.016 15.4 0.9 1 9.8 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 KUM60955.1 - 0.026 15.0 0.1 0.56 10.8 0.0 3.0 2 0 0 2 2 2 0 HEAT-like repeat Arm PF00514.23 KUM60955.1 - 0.32 11.1 6.4 45 4.3 0.1 5.3 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat Ubie_methyltran PF01209.18 KUM60956.1 - 3.3e-81 272.0 0.0 4.4e-81 271.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KUM60956.1 - 2e-16 60.5 0.0 3.9e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM60956.1 - 9.3e-15 55.1 0.0 1.9e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM60956.1 - 3.7e-11 43.1 0.0 5e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM60956.1 - 5.3e-11 43.1 0.0 9.8e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM60956.1 - 3.4e-06 27.0 0.0 5.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KUM60956.1 - 0.013 15.4 0.0 0.084 12.7 0.0 2.2 2 1 0 2 2 2 0 Hypothetical methyltransferase AA_permease PF00324.21 KUM60957.1 - 1.6e-106 356.8 42.6 1.8e-106 356.6 42.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM60957.1 - 1.1e-34 120.0 46.5 1.3e-34 119.8 46.5 1.0 1 0 0 1 1 1 1 Amino acid permease Halogen_Hydrol PF10112.9 KUM60957.1 - 4.5 7.2 7.0 31 4.5 2.2 2.7 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Aldedh PF00171.22 KUM60958.1 - 6.4e-107 357.9 0.1 7.8e-107 357.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AP_endonuc_2 PF01261.24 KUM60959.1 - 6.6e-40 136.8 0.0 8.4e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel zf-RING_4 PF14570.6 KUM60961.1 - 8.2e-20 70.3 13.5 1.5e-19 69.5 13.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KUM60961.1 - 1.3e-06 28.1 6.8 2.4e-06 27.3 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KUM60961.1 - 6.6e-05 22.7 0.0 0.00015 21.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 KUM60961.1 - 0.00038 20.7 10.6 0.0007 19.9 10.6 1.5 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 KUM60961.1 - 0.0021 18.0 4.5 0.004 17.1 4.5 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 KUM60961.1 - 0.0048 16.3 2.1 0.01 15.3 2.1 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 KUM60961.1 - 0.026 14.4 9.0 0.32 10.9 9.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KUM60961.1 - 0.047 13.6 12.2 0.096 12.6 12.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NS3 PF17530.2 KUM60961.1 - 0.21 11.1 1.3 0.36 10.4 1.3 1.3 1 0 0 1 1 1 0 Non-structural protein NS3 zf-RING_5 PF14634.6 KUM60961.1 - 0.35 10.9 11.7 0.64 10.0 11.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KUM60961.1 - 0.51 10.4 10.1 1 9.5 10.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.7 KUM60961.1 - 1.5 8.9 10.7 37 4.5 10.7 2.5 1 1 0 1 1 1 0 Double zinc ribbon Complex1_30kDa PF00329.19 KUM60962.1 - 2.2e-45 154.2 0.0 3.1e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF3817 PF12823.7 KUM60962.1 - 0.14 13.0 0.0 0.23 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3817) BUD22 PF09073.10 KUM60963.1 - 3.9e-101 339.5 19.2 4.5e-101 339.3 19.2 1.0 1 0 0 1 1 1 1 BUD22 Fungal_trans PF04082.18 KUM60964.1 - 1.5e-25 89.7 0.1 2.7e-25 88.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM60964.1 - 2.8e-05 24.1 10.8 4.9e-05 23.4 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Shikimate_DH PF01488.20 KUM60965.1 - 4.4e-05 23.6 0.0 0.0023 18.0 0.0 2.4 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pro_dh PF01619.18 KUM60966.1 - 9.6e-64 215.7 0.1 1.2e-63 215.4 0.1 1.1 1 0 0 1 1 1 1 Proline dehydrogenase AA_permease PF00324.21 KUM60967.1 - 4.9e-126 421.1 46.4 6.1e-126 420.8 46.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM60967.1 - 5e-26 91.5 50.8 6.3e-26 91.2 50.8 1.1 1 0 0 1 1 1 1 Amino acid permease NCE101 PF11654.8 KUM60967.1 - 0.021 14.5 0.5 0.052 13.3 0.5 1.7 1 0 0 1 1 1 0 Non-classical export protein 1 6PGD PF00393.19 KUM60968.1 - 3.7e-83 279.3 0.0 4.3e-83 279.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KUM60968.1 - 6.1e-37 127.2 0.0 1.8e-36 125.7 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KUM60968.1 - 0.00012 22.0 0.1 0.00022 21.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KUM60968.1 - 0.0014 18.0 0.1 0.0031 16.9 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KUM60968.1 - 0.0034 17.0 0.2 0.048 13.2 0.2 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 KUM60968.1 - 0.034 14.7 0.1 0.1 13.2 0.1 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KUM60968.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KUM60968.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Melibiase_2 PF16499.5 KUM60969.1 - 3.7e-56 190.4 6.8 5.6e-37 127.4 0.6 2.4 2 1 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KUM60969.1 - 1.7e-11 44.1 1.3 2e-10 40.6 0.2 2.4 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KUM60969.1 - 2.4e-08 33.3 0.1 5.6e-08 32.1 0.0 1.5 2 0 0 2 2 2 1 Melibiase PQQ_3 PF13570.6 KUM60970.1 - 6.5 7.4 7.3 0.92 10.1 0.7 3.1 3 0 0 3 3 3 0 PQQ-like domain WD40 PF00400.32 KUM60970.1 - 8.3 7.5 5.7 6.7 7.8 1.1 3.3 3 1 0 3 3 3 0 WD domain, G-beta repeat PALP PF00291.25 KUM60971.1 - 1.6e-67 228.0 0.1 2.1e-67 227.6 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Tim17 PF02466.19 KUM60972.1 - 2.9e-40 137.1 6.9 4.1e-40 136.6 6.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4048 PF13257.6 KUM60974.1 - 2.9e-83 279.6 23.0 2.9e-83 279.6 23.0 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF4048) Bap31_Bap29_C PF18035.1 KUM60974.1 - 0.064 13.3 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain ADIP PF11559.8 KUM60974.1 - 0.11 12.5 0.9 0.25 11.4 0.9 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding E3_UbLigase_EDD PF11547.8 KUM60974.1 - 0.17 11.6 0.1 0.46 10.2 0.0 1.8 2 0 0 2 2 2 0 E3 ubiquitin ligase EDD zf-CHY PF05495.12 KUM60975.1 - 8.4e-12 45.4 22.1 1.6e-11 44.5 22.1 1.4 1 0 0 1 1 1 1 CHY zinc finger Proteasome PF00227.26 KUM60976.1 - 7.9e-56 188.6 0.1 1.1e-55 188.1 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KUM60976.1 - 8.4e-14 50.9 0.3 3e-13 49.2 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 KUM60976.1 - 0.024 14.5 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) DUF4707 PF15806.5 KUM60976.1 - 0.13 11.2 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) zf-RanBP PF00641.18 KUM60977.1 - 1.2e-20 72.4 9.1 7.8e-11 41.1 1.5 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KUM60977.1 - 8.2e-08 32.0 0.0 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KUM60977.1 - 3.1e-06 27.8 0.0 4.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease zf-ribbon_3 PF13248.6 KUM60977.1 - 0.21 11.0 2.4 2.5 7.6 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KUM60977.1 - 0.58 10.2 5.0 2.9 8.0 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon Cnd3 PF12719.7 KUM60978.1 - 4e-89 298.7 0.1 3e-88 295.8 0.0 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KUM60978.1 - 2.6e-06 27.7 3.7 0.00012 22.4 0.2 3.5 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 KUM60978.1 - 7.9e-05 22.6 10.1 0.11 12.8 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 KUM60978.1 - 0.0037 17.3 0.4 0.37 10.8 0.0 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KUM60978.1 - 0.005 17.3 3.5 2 9.0 0.1 4.6 4 1 1 5 5 5 2 HEAT-like repeat DUF4521 PF15021.6 KUM60978.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) LID PF17916.1 KUM60978.1 - 2.3 7.9 5.7 1.4 8.6 0.2 3.1 3 0 0 3 3 3 0 LIM interaction domain (LID) Lactamase_B PF00753.27 KUM60979.1 - 4.2e-19 69.3 3.0 5.8e-19 68.9 3.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KUM60979.1 - 3.7e-05 23.3 0.2 5.2e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Epimerase PF01370.21 KUM60980.1 - 1.4e-16 60.7 0.0 3.2e-16 59.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KUM60980.1 - 1.8e-10 40.3 0.0 4.3e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KUM60980.1 - 1.2e-07 31.9 0.0 2.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KUM60980.1 - 2.9e-07 30.2 0.0 5.7e-06 26.0 0.0 2.3 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KUM60980.1 - 1.6e-06 27.5 0.1 0.0034 16.6 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.25 KUM60980.1 - 0.0003 20.3 0.4 0.0018 17.8 0.0 2.3 3 0 0 3 3 3 1 short chain dehydrogenase NmrA PF05368.13 KUM60980.1 - 0.0013 18.4 0.0 0.015 14.8 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KUM60980.1 - 0.0016 17.6 0.0 0.003 16.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TRI5 PF06330.11 KUM60981.1 - 3.2e-27 95.3 1.0 4.3e-27 94.9 1.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF5616 PF18481.1 KUM60981.1 - 0.12 12.7 0.0 0.46 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5616) MFS_1 PF07690.16 KUM60982.1 - 2.3e-36 125.5 50.7 6.2e-36 124.0 50.0 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM60982.1 - 1.3e-14 53.5 12.0 1.3e-14 53.5 12.0 2.1 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) zf-CHCC PF10276.9 KUM60983.1 - 5.6e-17 61.5 0.8 1e-16 60.7 0.8 1.4 1 0 0 1 1 1 1 Zinc-finger domain UPF0047 PF01894.17 KUM60984.1 - 1.8e-37 128.0 0.0 2.1e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 CoaE PF01121.20 KUM60985.1 - 1.3e-41 142.3 0.0 1.8e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KUM60985.1 - 0.0066 17.0 0.3 0.49 10.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain 2TM PF13239.6 KUM60985.1 - 0.078 13.3 0.5 0.15 12.4 0.5 1.5 1 0 0 1 1 1 0 2TM domain MPP6 PF10175.9 KUM60986.1 - 1.8e-07 31.7 17.0 5.1e-05 23.8 17.0 3.1 1 1 0 1 1 1 1 M-phase phosphoprotein 6 Myc_N PF01056.18 KUM60986.1 - 0.027 14.4 8.1 0.035 14.0 8.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Peptidase_S64 PF08192.11 KUM60986.1 - 1 7.8 5.0 1.3 7.4 5.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 Lipase_3 PF01764.25 KUM60987.1 - 7.7e-36 123.1 0.0 1.1e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KUM60987.1 - 1.5e-08 34.5 0.2 2.9e-08 33.6 0.2 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 KUM60987.1 - 1.1e-05 24.9 0.0 1.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KUM60987.1 - 0.00039 20.1 0.0 0.0014 18.3 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase DUF2974 PF11187.8 KUM60987.1 - 0.0069 16.0 0.0 0.016 14.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Thioesterase PF00975.20 KUM60987.1 - 0.025 14.7 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF3431 PF11913.8 KUM60988.1 - 2.9e-90 301.8 0.2 6.8e-90 300.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) SLC3A2_N PF16028.5 KUM60990.1 - 0.4 10.3 1.9 0.38 10.3 0.8 1.5 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Pkinase PF00069.25 KUM60992.1 - 3.8e-07 29.7 0.0 6.3e-06 25.7 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain DJ-1_PfpI PF01965.24 KUM60994.1 - 1.2e-09 38.2 0.0 1.4e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Fungal_trans PF04082.18 KUM60995.1 - 8.7e-05 21.7 0.0 0.00017 20.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_32N PF00251.20 KUM60996.1 - 1.3e-91 307.3 2.9 1.7e-91 307.0 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KUM60996.1 - 4.7e-30 104.7 1.5 8.1e-30 103.9 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Sortilin-Vps10 PF15902.5 KUM60996.1 - 0.0045 15.8 0.2 0.019 13.8 0.0 1.9 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, CHB_HEX_C PF03174.13 KUM60996.1 - 0.019 14.9 0.1 0.064 13.2 0.1 1.8 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF3431 PF11913.8 KUM60998.1 - 1.1e-81 273.8 0.1 1.3e-81 273.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) F-box-like PF12937.7 KUM60999.1 - 4.5e-06 26.4 0.1 1.3e-05 25.0 0.1 1.8 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KUM60999.1 - 0.02 15.3 0.5 9 6.9 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) GFA PF04828.14 KUM61000.1 - 4.4e-11 43.0 2.2 7.6e-11 42.2 2.2 1.4 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-LSD1 PF06943.12 KUM61000.1 - 0.43 10.5 6.6 6.5 6.7 0.2 2.4 2 0 0 2 2 2 0 LSD1 zinc finger DUF5340 PF17275.2 KUM61001.1 - 0.18 11.9 0.4 1.1 9.4 0.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5340) ADH_zinc_N PF00107.26 KUM61002.1 - 6e-09 36.0 0.4 1.1e-08 35.2 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM61002.1 - 1.2e-06 28.4 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KUM61002.1 - 0.0057 17.7 0.0 0.011 16.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NUDIX_2 PF13869.6 KUM61003.1 - 1.8e-80 269.0 0.0 2.2e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase iPGM_N PF06415.13 KUM61004.1 - 1.8e-74 249.9 0.0 2.6e-74 249.3 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KUM61004.1 - 7.9e-70 235.0 0.0 9.7e-70 234.8 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 KUM61004.1 - 1.3e-07 31.6 0.0 2.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KUM61004.1 - 3.9e-05 23.2 0.0 0.0001 21.8 0.0 1.7 1 1 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.20 KUM61004.1 - 0.052 12.5 0.0 0.15 11.0 0.0 1.6 2 0 0 2 2 2 0 Alkaline phosphatase AMMECR1 PF01871.17 KUM61005.1 - 2.9e-35 121.3 0.0 2.7e-33 114.9 0.0 2.4 1 1 0 1 1 1 1 AMMECR1 Apt1 PF10351.9 KUM61005.1 - 0.051 12.4 5.2 0.057 12.3 5.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RP-C_C PF11800.8 KUM61005.1 - 0.3 11.1 3.5 0.41 10.7 3.5 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Macoilin PF09726.9 KUM61005.1 - 0.56 8.7 8.4 0.72 8.3 8.4 1.1 1 0 0 1 1 1 0 Macoilin family AF-4 PF05110.13 KUM61005.1 - 1.1 7.3 20.8 1.4 6.9 20.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SPX PF03105.19 KUM61005.1 - 5 6.9 14.6 7.2 6.4 14.6 1.1 1 0 0 1 1 1 0 SPX domain Pkinase PF00069.25 KUM61006.1 - 1.6e-73 247.4 0.0 2e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM61006.1 - 3.8e-30 105.1 0.0 4.8e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM61006.1 - 1.7e-07 30.9 0.0 2.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KUM61006.1 - 6.9e-05 21.8 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KUM61006.1 - 0.00012 21.5 0.0 0.00024 20.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KUM61006.1 - 0.00042 20.3 0.1 0.00069 19.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family SHMT PF00464.19 KUM61007.1 - 1.3e-207 689.1 0.0 1.5e-207 688.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KUM61007.1 - 5e-06 25.9 0.0 1.1e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KUM61007.1 - 0.0036 16.3 0.0 0.0054 15.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KUM61007.1 - 0.019 14.2 0.0 0.036 13.4 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KUM61007.1 - 0.09 11.3 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme HNH_2 PF13391.6 KUM61008.1 - 5.7e-14 52.0 0.0 1.3e-13 50.8 0.0 1.6 2 0 0 2 2 2 1 HNH endonuclease Nop PF01798.18 KUM61010.1 - 8.3e-89 297.0 0.1 8.3e-89 297.0 0.1 1.5 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KUM61010.1 - 9.5e-20 70.8 0.1 5.1e-19 68.4 0.1 2.4 1 0 0 1 1 1 1 NOP5NT (NUC127) domain LPP20 PF02169.16 KUM61010.1 - 1.1 9.6 4.2 0.47 10.8 1.1 2.0 2 0 0 2 2 2 0 LPP20 lipoprotein RNA_polI_A34 PF08208.11 KUM61010.1 - 9.6 6.2 31.2 18 5.4 31.2 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF1744 PF08490.12 KUM61011.1 - 1.1e-149 498.5 0.0 1.6e-149 497.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KUM61011.1 - 4.8e-85 285.7 1.8 1.3e-84 284.2 0.8 2.2 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KUM61011.1 - 6.8e-15 54.7 0.0 4.1e-11 42.3 0.0 3.7 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KUM61011.1 - 9.7e-07 28.7 0.2 3e-06 27.1 0.2 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KUM61011.1 - 0.00016 21.7 0.0 0.00066 19.7 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily DNA_pol3_alpha PF07733.12 KUM61011.1 - 0.064 12.8 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha NTPase domain zf-CHY PF05495.12 KUM61011.1 - 0.15 12.6 2.1 0.52 10.8 2.1 1.9 1 0 0 1 1 1 0 CHY zinc finger DUF3767 PF12597.8 KUM61012.1 - 6.4e-31 106.2 0.0 8.9e-31 105.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) TMA7 PF09072.10 KUM61012.1 - 1.1 10.2 6.7 0.55 11.1 4.3 1.7 2 0 0 2 2 2 0 Translation machinery associated TMA7 Folliculin PF11704.8 KUM61013.1 - 2.1e-52 177.7 0.0 3.3e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport CSN8_PSD8_EIF3K PF10075.9 KUM61014.1 - 9.4e-50 168.3 0.0 1.2e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family FGAR-AT_linker PF18072.1 KUM61014.1 - 0.13 12.8 0.5 13 6.4 0.5 3.0 2 1 1 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain Cnn_1N PF07989.11 KUM61015.1 - 1.2e-22 79.8 5.0 1.2e-22 79.8 5.0 14.4 6 3 9 15 15 15 4 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 KUM61015.1 - 4e-22 78.6 1.7 4e-22 78.6 1.7 3.9 3 1 1 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Pox_A_type_inc PF04508.12 KUM61015.1 - 2.4 8.1 0.0 2.4 8.1 0.0 9.4 10 0 0 10 10 10 0 Viral A-type inclusion protein repeat Fez1 PF06818.15 KUM61015.1 - 8.5 6.8 160.8 0.043 14.3 17.0 7.8 1 1 5 7 7 7 0 Fez1 SGT1 PF07093.11 KUM61016.1 - 2.6e-93 313.5 20.3 2.2e-86 290.6 0.0 2.1 1 1 1 2 2 2 2 SGT1 protein Prefoldin_2 PF01920.20 KUM61017.1 - 6.2e-23 80.8 13.8 8.7e-23 80.3 13.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit Spc24 PF08286.11 KUM61017.1 - 2.1e-05 24.7 12.8 0.002 18.3 2.7 2.1 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 APG6_N PF17675.1 KUM61017.1 - 0.0094 16.5 20.4 0.053 14.0 6.8 2.0 1 1 1 2 2 2 2 Apg6 coiled-coil region Uds1 PF15456.6 KUM61017.1 - 0.0094 16.1 5.4 0.014 15.5 5.4 1.2 1 0 0 1 1 1 1 Up-regulated During Septation Prefoldin PF02996.17 KUM61017.1 - 0.012 15.5 12.2 0.027 14.4 12.2 1.5 1 1 0 1 1 1 0 Prefoldin subunit Prefoldin_3 PF13758.6 KUM61017.1 - 0.012 15.6 5.2 0.02 14.9 5.2 1.4 1 0 0 1 1 1 0 Prefoldin subunit Rh5 PF18515.1 KUM61017.1 - 0.018 14.4 0.5 0.022 14.1 0.5 1.2 1 0 0 1 1 1 0 Rh5 coiled-coil domain PHM7_cyt PF14703.6 KUM61017.1 - 0.029 14.6 5.1 0.046 13.9 5.1 1.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter THOC7 PF05615.13 KUM61017.1 - 0.06 13.6 12.2 0.12 12.7 12.2 1.5 1 1 0 1 1 1 0 Tho complex subunit 7 Chibby PF14645.6 KUM61017.1 - 0.065 13.6 7.6 0.79 10.1 2.1 3.0 1 1 2 3 3 3 0 Chibby family TMF_TATA_bd PF12325.8 KUM61017.1 - 0.095 12.9 14.5 1.1 9.6 2.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding XhlA PF10779.9 KUM61017.1 - 0.1 12.8 1.2 0.1 12.8 1.2 2.0 2 1 0 2 2 2 0 Haemolysin XhlA DUF5082 PF16888.5 KUM61017.1 - 0.13 12.6 13.3 0.76 10.1 13.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 KUM61017.1 - 0.13 11.2 15.1 0.16 10.8 15.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 KUM61017.1 - 0.13 11.5 16.6 1.8 7.9 4.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KUM61017.1 - 0.19 11.8 16.5 0.39 10.8 3.1 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 KUM61017.1 - 0.2 11.4 18.5 0.73 9.6 1.1 3.2 2 1 1 3 3 3 0 Septum formation initiator COG2 PF06148.11 KUM61017.1 - 0.22 11.6 8.3 0.91 9.6 2.2 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Rx_N PF18052.1 KUM61017.1 - 0.24 11.7 8.2 1 9.7 1.5 2.2 2 0 0 2 2 2 0 Rx N-terminal domain Occludin_ELL PF07303.13 KUM61017.1 - 0.28 11.9 6.9 0.74 10.6 0.7 2.2 2 0 0 2 2 2 0 Occludin homology domain DHR10 PF18595.1 KUM61017.1 - 0.28 11.2 19.6 0.075 13.1 4.6 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain MMPL PF03176.15 KUM61017.1 - 0.33 9.8 2.7 0.4 9.6 2.7 1.3 1 1 0 1 1 1 0 MMPL family bZIP_1 PF00170.21 KUM61017.1 - 0.34 11.0 9.7 2.6 8.2 0.6 2.7 2 1 1 3 3 3 0 bZIP transcription factor YabA PF06156.13 KUM61017.1 - 0.35 11.5 13.0 1.4 9.6 2.9 2.1 1 1 1 2 2 2 0 Initiation control protein YabA FlaC_arch PF05377.11 KUM61017.1 - 0.35 11.3 12.4 1.7 9.1 3.1 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) HAP1_N PF04849.13 KUM61017.1 - 0.39 9.9 15.8 1.3 8.1 15.8 1.7 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF948 PF06103.11 KUM61017.1 - 0.47 10.7 7.4 1.8 8.9 0.7 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HalX PF08663.10 KUM61017.1 - 0.55 10.6 9.0 1.4 9.3 0.6 3.0 2 2 0 2 2 2 0 HalX domain JIP_LZII PF16471.5 KUM61017.1 - 0.73 10.1 11.0 2.3 8.5 1.8 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II CorA PF01544.18 KUM61017.1 - 0.73 9.1 7.7 4.6 6.5 7.8 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein CLZ PF16526.5 KUM61017.1 - 0.82 10.1 12.9 0.63 10.4 2.6 2.4 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 KUM61017.1 - 1 8.6 12.7 1.8 7.9 12.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Osmo_CC PF08946.10 KUM61017.1 - 1.2 9.5 10.7 0.091 13.0 3.3 2.5 2 1 0 2 2 2 0 Osmosensory transporter coiled coil DUF1664 PF07889.12 KUM61017.1 - 1.6 8.8 10.5 2.1 8.4 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fmp27_WPPW PF10359.9 KUM61017.1 - 1.9 7.2 12.5 3.9 6.2 1.8 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain ABC_tran_CTD PF16326.5 KUM61017.1 - 2.2 8.6 19.1 2.5 8.4 1.0 3.2 2 2 1 3 3 3 0 ABC transporter C-terminal domain NPV_P10 PF05531.12 KUM61017.1 - 2.3 8.7 9.2 9.3 6.8 2.9 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ERM PF00769.19 KUM61017.1 - 2.8 7.7 18.0 5.9 6.6 18.0 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Sec34 PF04136.15 KUM61017.1 - 4.3 7.2 10.8 3.6 7.4 1.6 2.1 2 0 0 2 2 2 0 Sec34-like family UPF0242 PF06785.11 KUM61017.1 - 4.4 7.4 19.8 6.2 6.9 5.6 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TolA_bind_tri PF16331.5 KUM61017.1 - 5.7 7.1 21.5 11 6.1 4.5 2.9 2 1 0 2 2 2 0 TolA binding protein trimerisation Siah-Interact_N PF09032.11 KUM61017.1 - 7.9 6.9 15.2 10 6.5 4.9 2.5 1 1 1 2 2 2 0 Siah interacting protein, N terminal Fib_alpha PF08702.10 KUM61017.1 - 8.8 6.5 11.8 36 4.5 11.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family AAA PF00004.29 KUM61018.1 - 5.1e-42 143.4 0.0 8.6e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KUM61018.1 - 2.2e-29 101.2 0.0 8.4e-29 99.4 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KUM61018.1 - 2e-23 82.2 2.0 2e-23 82.2 2.0 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KUM61018.1 - 4.7e-06 26.3 0.0 2e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KUM61018.1 - 8.9e-06 25.5 0.0 2.2e-05 24.3 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KUM61018.1 - 1.5e-05 25.5 0.0 0.00018 22.0 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KUM61018.1 - 2.7e-05 24.2 0.0 0.00012 22.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KUM61018.1 - 4.5e-05 23.8 0.0 0.011 16.1 0.0 2.8 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.13 KUM61018.1 - 4.5e-05 22.7 0.0 0.001 18.3 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KUM61018.1 - 7.3e-05 22.6 0.0 0.00016 21.4 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KUM61018.1 - 0.0001 22.6 0.1 0.019 15.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 KUM61018.1 - 0.00012 21.5 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 KUM61018.1 - 0.00019 21.6 0.0 0.0073 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KUM61018.1 - 0.00033 20.7 0.0 0.00068 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KUM61018.1 - 0.0005 20.6 0.0 0.0016 19.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KUM61018.1 - 0.0012 18.6 0.0 0.011 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KUM61018.1 - 0.0015 18.7 0.0 0.004 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KUM61018.1 - 0.0079 15.8 0.2 0.65 9.5 0.1 2.9 2 1 0 3 3 3 1 AAA domain AAA_17 PF13207.6 KUM61018.1 - 0.01 16.2 0.1 0.036 14.5 0.0 2.0 2 1 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KUM61018.1 - 0.013 15.0 0.0 0.089 12.3 0.0 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region USP8_dimer PF08969.11 KUM61018.1 - 0.017 15.3 3.1 0.036 14.3 3.1 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain Mg_chelatase PF01078.21 KUM61018.1 - 0.018 14.4 0.1 0.071 12.5 0.1 2.0 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 KUM61018.1 - 0.046 13.8 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 Torsin ATPase_2 PF01637.18 KUM61018.1 - 0.053 13.4 1.0 1.3 8.9 0.0 2.8 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KUM61018.1 - 0.062 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 KUM61018.1 - 0.069 12.6 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 KUM61018.1 - 0.08 12.9 0.0 0.71 9.8 0.0 2.1 1 1 1 2 2 2 0 NACHT domain AFG1_ATPase PF03969.16 KUM61018.1 - 0.17 10.8 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Cytidylate_kin PF02224.18 KUM61018.1 - 0.23 11.1 1.2 0.51 10.0 0.0 2.1 2 1 1 3 3 3 0 Cytidylate kinase Med9 PF07544.13 KUM61019.1 - 2.3e-17 62.8 0.0 7.1e-17 61.3 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 KUM61019.1 - 0.0095 16.2 2.6 0.013 15.7 2.6 1.5 1 1 0 1 1 1 1 Subunit 21 of Mediator complex DUF3782 PF12644.7 KUM61019.1 - 0.09 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) GP41 PF00517.17 KUM61019.1 - 0.098 12.6 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 Retroviral envelope protein SlyX PF04102.12 KUM61019.1 - 0.12 13.0 0.1 0.22 12.1 0.1 1.5 1 0 0 1 1 1 0 SlyX RRM_1 PF00076.22 KUM61020.1 - 7.7e-10 38.5 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gp-FAR-1 PF05823.12 KUM61020.1 - 0.17 12.2 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FAM184 PF15665.5 KUM61020.1 - 0.2 11.4 0.9 0.29 10.9 0.1 1.6 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B tRNA-synt_2 PF00152.20 KUM61021.1 - 1.8e-66 224.4 0.0 6.8e-66 222.5 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KUM61021.1 - 1.6e-05 24.8 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Gti1_Pac2 PF09729.9 KUM61022.1 - 2.7e-44 151.4 8.9 1.9e-37 129.1 0.1 3.1 2 1 1 3 3 3 3 Gti1/Pac2 family DAO PF01266.24 KUM61023.1 - 3.6e-06 26.8 0.4 4.1e-06 26.6 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KUM61023.1 - 0.018 15.3 0.1 0.027 14.7 0.1 1.3 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KUM61023.1 - 0.019 14.2 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Thi4 family Cpn60_TCP1 PF00118.24 KUM61024.1 - 2.2e-164 547.7 0.2 2.5e-164 547.6 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MOZ_SAS PF01853.18 KUM61025.1 - 8e-62 208.1 0.0 1.2e-61 207.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KUM61025.1 - 9.2e-17 60.4 0.3 1.6e-16 59.6 0.3 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain RrnaAD PF00398.20 KUM61025.1 - 0.12 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase zf-RING_2 PF13639.6 KUM61026.1 - 1.6e-08 34.7 2.9 2.4e-08 34.2 2.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KUM61026.1 - 3.3e-06 27.3 3.3 1.8e-05 24.9 3.3 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KUM61026.1 - 0.00022 21.2 0.7 0.00035 20.6 0.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KUM61026.1 - 0.00051 20.0 6.4 0.00082 19.3 6.4 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KUM61026.1 - 0.004 17.0 4.0 0.011 15.5 3.9 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 KUM61026.1 - 0.005 17.1 0.4 0.012 15.9 0.4 1.6 1 0 0 1 1 1 1 zinc-ribbon zf-C3HC4 PF00097.25 KUM61026.1 - 0.028 14.3 1.3 0.048 13.5 1.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KUM61026.1 - 0.041 13.6 1.7 0.068 12.9 1.7 1.4 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 KUM61026.1 - 0.29 11.0 2.2 1.4 8.8 2.2 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Asparaginase_2 PF01112.18 KUM61027.1 - 1.2e-57 195.3 0.0 4.4e-50 170.5 0.0 3.6 3 1 0 3 3 3 2 Asparaginase Glyoxalase PF00903.25 KUM61030.1 - 5.5e-21 75.1 0.9 6.1e-16 58.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KUM61030.1 - 2.2e-12 47.2 0.2 2.2e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 KUM61030.1 - 4.8e-06 26.8 0.3 0.00013 22.2 0.1 2.5 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 KUM61030.1 - 5e-06 26.8 0.2 0.24 11.5 0.0 3.0 3 1 0 3 3 3 2 Glyoxalase-like domain Atx10homo_assoc PF09759.9 KUM61031.1 - 1.8e-31 108.0 0.4 5.1e-31 106.6 0.1 1.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DUF2722 PF10846.8 KUM61031.1 - 1.8 7.4 4.1 3.4 6.5 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF5411 PF17424.2 KUM61032.1 - 0.11 12.4 0.6 0.14 12.1 0.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5411) Chromo_shadow PF01393.19 KUM61033.1 - 3.5e-18 65.4 1.5 4.6e-15 55.5 0.1 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KUM61033.1 - 3.7e-12 46.0 1.3 6.9e-12 45.1 1.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Rap1_C PF11626.8 KUM61034.1 - 1.5e-21 76.2 0.0 5.2e-21 74.5 0.0 1.8 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 KUM61034.1 - 1e-13 51.2 6.0 2.6e-05 24.3 1.5 3.5 2 1 0 3 3 3 3 Rap1 Myb domain BRCT_2 PF16589.5 KUM61034.1 - 2.3e-10 40.7 0.0 4.5e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DHHC PF01529.20 KUM61035.1 - 7e-31 107.1 8.8 7e-31 107.1 8.8 2.0 3 0 0 3 3 3 1 DHHC palmitoyltransferase zf-CHY PF05495.12 KUM61036.1 - 8.3e-13 48.6 10.1 8.3e-13 48.6 10.1 2.5 2 1 0 2 2 2 1 CHY zinc finger Paired_CXXCH_1 PF09699.10 KUM61036.1 - 0.11 12.3 7.8 0.23 11.2 0.2 2.6 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) zinc_ribbon_15 PF17032.5 KUM61037.1 - 0.00053 20.7 1.3 0.0011 19.7 1.3 1.5 1 0 0 1 1 1 1 zinc-ribbon family zf_CCCH_4 PF18345.1 KUM61037.1 - 0.0016 18.4 3.2 0.0034 17.4 3.2 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KUM61037.1 - 0.0026 17.6 2.7 0.0046 16.8 2.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PHF5 PF03660.14 KUM61037.1 - 0.16 12.2 2.2 0.37 11.0 2.2 1.5 1 0 0 1 1 1 0 PHF5-like protein zf-CCCH_4 PF18044.1 KUM61037.1 - 0.43 10.4 2.8 0.85 9.5 2.8 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KUM61037.1 - 1.2 9.8 2.7 2.2 8.9 2.7 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF3295 PF11702.8 KUM61038.1 - 4.6e-193 643.1 23.6 5.3e-193 642.9 23.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KUM61038.1 - 2.4e-12 46.5 1.9 6.2e-12 45.1 1.9 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MSP1_C PF07462.11 KUM61038.1 - 0.76 8.4 2.3 1.3 7.7 2.3 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Cpn60_TCP1 PF00118.24 KUM61039.1 - 5.4e-156 520.0 4.4 6.2e-156 519.8 4.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NTP_transferase PF00483.23 KUM61042.1 - 5.5e-31 108.0 0.0 7.6e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KUM61042.1 - 3.7e-09 35.9 5.6 7.3e-06 25.5 0.1 3.5 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KUM61042.1 - 8e-09 36.0 0.0 1.2e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 KUM61042.1 - 0.007 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase SusD-like_3 PF14322.6 KUM61045.1 - 0.22 11.8 0.0 0.28 11.5 0.0 1.2 1 0 0 1 1 1 0 Starch-binding associating with outer membrane FAA_hydrolase PF01557.18 KUM61046.1 - 7.5e-55 185.9 0.0 1e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KUM61046.1 - 3.7e-31 107.5 0.0 6e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal GST_N_2 PF13409.6 KUM61047.1 - 2.1e-12 47.2 0.1 5.1e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KUM61047.1 - 6.1e-12 45.8 0.0 1.1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KUM61047.1 - 4.7e-11 42.9 0.0 7.1e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KUM61047.1 - 6e-07 29.6 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KUM61047.1 - 1.9e-05 24.8 0.1 4.8e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KUM61047.1 - 0.027 14.5 0.1 0.046 13.7 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TPR_17 PF13431.6 KUM61048.1 - 0.005 17.1 0.1 0.13 12.7 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2313 PF10076.9 KUM61048.1 - 0.16 11.9 0.0 0.69 9.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) TPR_11 PF13414.6 KUM61048.1 - 0.22 11.3 0.3 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 TPR repeat HgmA PF04209.13 KUM61049.1 - 5.5e-210 697.4 0.3 6.3e-210 697.2 0.3 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase eIF3m_C_helix PF18005.1 KUM61050.1 - 3.5e-11 42.6 3.2 8.1e-11 41.4 3.2 1.7 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 KUM61050.1 - 1.3e-10 41.7 0.0 3.2e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 PCI domain STAS_2 PF13466.6 KUM61050.1 - 0.092 13.1 1.6 1.2 9.6 0.0 3.0 2 1 0 2 2 2 0 STAS domain Hexokinase_2 PF03727.16 KUM61051.1 - 2.4e-58 197.4 0.0 3.5e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KUM61051.1 - 1.4e-46 158.9 0.0 2.1e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Acyl_transf_1 PF00698.21 KUM61053.1 - 1.4e-52 179.2 0.0 2e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KUM61053.1 - 1e-44 153.0 0.0 1.6e-44 152.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KUM61053.1 - 9.7e-18 64.7 0.0 2.2e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension SAT PF16073.5 KUM61053.1 - 0.013 15.2 0.1 1.3 8.7 0.0 3.0 2 1 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis KR PF08659.10 KUM61054.1 - 1.9e-62 210.3 0.0 4.2e-62 209.3 0.0 1.6 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 KUM61054.1 - 1.3e-16 61.8 0.0 9.2e-16 59.1 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KUM61054.1 - 1.5e-14 53.9 0.7 4.5e-14 52.4 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KUM61054.1 - 6.1e-14 52.1 0.1 2.9e-13 49.9 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KUM61054.1 - 8.3e-11 41.9 0.2 2.5e-10 40.3 0.1 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KUM61054.1 - 1e-06 29.0 1.2 8.4e-06 26.1 1.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site PALP PF00291.25 KUM61054.1 - 0.039 13.4 0.6 0.23 10.8 0.1 2.1 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Shikimate_DH PF01488.20 KUM61054.1 - 0.17 11.9 0.3 0.91 9.6 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_1 PF00175.21 KUM61055.1 - 8.3e-28 97.2 0.0 1.3e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KUM61055.1 - 1.2e-16 60.9 0.0 2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KUM61055.1 - 1.6e-07 31.6 0.0 0.00063 19.9 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain CDO_I PF05995.12 KUM61056.1 - 4.7e-40 136.7 0.1 6.6e-40 136.2 0.1 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KUM61056.1 - 0.0045 16.5 0.1 0.0072 15.8 0.1 1.4 1 1 0 1 1 1 1 PCO_ADO Arylsulfotran_2 PF14269.6 KUM61058.1 - 1.9e-43 149.0 1.2 7.2e-43 147.1 0.9 2.0 3 0 0 3 3 3 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KUM61058.1 - 5.5e-13 48.6 1.9 8.4e-12 44.7 1.9 2.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MTP18 PF10558.9 KUM61058.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Fungal_trans PF04082.18 KUM61059.1 - 5.2e-16 58.5 1.4 8.9e-16 57.7 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MinC_N PF05209.13 KUM61059.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain Stk19 PF10494.9 KUM61060.1 - 3.8e-90 301.9 0.0 4.6e-90 301.6 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Glyco_transf_20 PF00982.21 KUM61061.1 - 1.2e-159 532.0 0.0 2.2e-159 531.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KUM61061.1 - 1.8e-39 135.3 0.0 2.8e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase GST_C_3 PF14497.6 KUM61062.1 - 7e-05 22.9 0.0 0.00015 21.9 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KUM61062.1 - 0.00011 22.4 0.0 0.00062 19.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KUM61062.1 - 0.00011 22.1 0.2 0.00045 20.2 0.2 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KUM61062.1 - 0.0003 21.1 0.4 0.00071 19.9 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KUM61062.1 - 0.0028 17.9 0.1 0.005 17.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KUM61062.1 - 0.052 14.0 0.1 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Na_Ca_ex PF01699.24 KUM61063.1 - 3e-52 176.6 42.3 8.4e-29 100.5 17.0 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Cnd2 PF05786.14 KUM61064.1 - 0 1041.9 2.5 0 1041.7 2.5 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KUM61064.1 - 0.011 15.9 0.0 0.043 14.0 0.0 2.0 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Phage_Gp23 PF10669.9 KUM61065.1 - 0.02 15.2 1.0 1.4 9.3 0.4 2.6 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) FixQ PF05545.11 KUM61065.1 - 0.02 14.8 4.7 0.67 10.0 0.2 2.9 2 1 1 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF1218 PF06749.12 KUM61065.1 - 0.031 14.8 1.4 0.031 14.8 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) EphA2_TM PF14575.6 KUM61065.1 - 0.079 13.8 0.3 6.1 7.8 0.0 3.2 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF4337 PF14235.6 KUM61065.1 - 0.23 11.6 0.2 1.8 8.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Cation_efflux PF01545.21 KUM61065.1 - 1.9 8.1 5.6 8.3 6.1 5.7 2.0 1 1 0 1 1 1 0 Cation efflux family DUF2569 PF10754.9 KUM61065.1 - 5.6 7.4 9.3 1.3 9.5 2.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2569) DUF202 PF02656.15 KUM61065.1 - 5.7 7.4 10.9 1.2 9.7 1.2 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF202) zf-H2C2_2 PF13465.6 KUM61066.1 - 1e-11 44.6 16.7 1.9e-06 28.1 1.9 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KUM61066.1 - 5.7e-10 39.1 21.4 0.00087 19.6 4.7 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM61066.1 - 6.1e-07 29.8 19.0 0.021 15.6 3.7 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KUM61066.1 - 2e-06 27.7 15.9 0.0055 16.7 0.0 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 KUM61066.1 - 0.0043 17.3 9.0 0.012 15.9 5.5 2.7 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 KUM61066.1 - 0.0079 16.3 6.5 0.018 15.1 1.7 2.5 2 0 0 2 2 2 1 Zinc ribbon domain Rad50_zn_hook PF04423.14 KUM61066.1 - 0.011 15.5 2.1 0.23 11.3 0.3 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_9 PF16293.5 KUM61066.1 - 0.014 15.2 1.7 3 7.8 0.2 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KUM61066.1 - 0.041 13.8 0.9 0.041 13.8 0.9 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2HE PF16278.5 KUM61066.1 - 0.054 14.0 14.5 0.11 13.0 1.6 3.1 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DZR PF12773.7 KUM61066.1 - 0.094 12.8 6.7 0.82 9.8 6.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.19 KUM61066.1 - 0.18 11.9 2.7 0.47 10.5 2.7 1.6 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CHCC PF10276.9 KUM61066.1 - 0.44 10.7 5.7 5.4 7.1 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger domain zinc_ribbon_9 PF14369.6 KUM61066.1 - 0.44 10.8 4.0 27 5.1 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon zf-C2H2_jaz PF12171.8 KUM61066.1 - 0.78 10.1 12.9 0.4 11.0 1.2 3.6 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding zinc-ribbons_6 PF07191.12 KUM61066.1 - 1.4 8.9 5.0 5.7 7.0 5.0 1.9 1 1 0 1 1 1 0 zinc-ribbons zf-FPG_IleRS PF06827.14 KUM61066.1 - 1.7 8.6 6.4 2 8.3 0.6 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-ISL3 PF14690.6 KUM61066.1 - 3 8.6 9.5 11 6.8 0.3 3.3 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 FYDLN_acid PF09538.10 KUM61066.1 - 3.7 8.3 11.4 0.51 11.0 1.4 3.3 2 2 1 3 3 3 0 Protein of unknown function (FYDLN_acid) Zn_ribbon_SprT PF17283.2 KUM61066.1 - 5.9 6.9 11.7 13 5.8 0.8 2.5 1 1 2 3 3 3 0 SprT-like zinc ribbon domain zf-C2H2_3rep PF18868.1 KUM61066.1 - 9.3 6.9 8.5 9.7 6.9 2.8 3.3 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF3074 PF11274.8 KUM61067.1 - 2.4e-35 122.2 0.0 3e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) ketoacyl-synt PF00109.26 KUM61068.1 - 1.5e-70 237.6 0.0 1.7e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 KUM61068.1 - 0.00022 20.7 0.3 0.00067 19.1 0.2 1.7 1 1 1 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KUM61068.1 - 0.0009 19.0 0.8 0.0097 15.7 0.8 2.2 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FSH1 PF03959.13 KUM61069.1 - 2e-11 43.9 0.0 2.9e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Cutinase PF01083.22 KUM61070.1 - 8.4e-20 71.5 0.0 1.1e-19 71.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase ADK PF00406.22 KUM61072.1 - 1.7e-42 145.0 0.0 2.3e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KUM61072.1 - 2.2e-32 112.3 0.0 3e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KUM61072.1 - 6.6e-08 33.2 0.0 9.6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KUM61072.1 - 2.1e-07 31.2 0.1 8.1e-06 26.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KUM61072.1 - 2.8e-06 27.1 0.0 0.00058 19.6 0.0 2.2 1 1 0 1 1 1 1 Thymidylate kinase Ploopntkinase3 PF18751.1 KUM61072.1 - 0.071 13.0 0.1 0.21 11.5 0.0 1.9 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 DUF4304 PF14137.6 KUM61072.1 - 0.15 12.2 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4304) Phytochelatin_C PF09328.10 KUM61073.1 - 1.8 7.8 4.5 0.24 10.7 0.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1984) Herpes_capsid PF06112.11 KUM61073.1 - 3.9 7.5 11.6 6.2 6.9 11.6 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF4680 PF15730.5 KUM61073.1 - 4 7.8 6.7 6.4 7.1 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) 4HBT PF03061.22 KUM61074.1 - 2.2e-07 31.1 0.1 3.7e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KUM61075.1 - 4.2e-53 181.1 0.7 4.9e-53 180.9 0.7 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily RTA1 PF04479.13 KUM61076.1 - 5.6e-53 179.6 13.1 5.6e-53 179.6 13.1 1.6 1 1 1 2 2 2 1 RTA1 like protein DUF2721 PF11026.8 KUM61076.1 - 1.7 8.6 13.3 2.2 8.2 0.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DUF4491 PF14898.6 KUM61076.1 - 6.6 7.2 15.9 0.69 10.4 1.2 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4491) FMN_dh PF01070.18 KUM61077.1 - 2e-117 392.2 0.0 2.7e-117 391.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KUM61077.1 - 2.2e-07 30.2 0.0 4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KUM61077.1 - 4.6e-05 22.7 0.0 7.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KUM61077.1 - 0.00056 19.4 0.0 0.034 13.6 0.0 2.4 1 1 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 KUM61077.1 - 0.0024 17.3 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 KUM61077.1 - 0.0039 16.5 0.0 0.011 15.0 0.1 1.8 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.14 KUM61077.1 - 0.0058 16.0 0.0 0.36 10.1 0.0 2.4 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG bZIP_1 PF00170.21 KUM61078.1 - 0.00078 19.5 1.7 0.0019 18.3 1.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor Tropomyosin_1 PF12718.7 KUM61078.1 - 0.043 14.0 0.2 0.072 13.3 0.2 1.3 1 0 0 1 1 1 0 Tropomyosin like DHDPS PF00701.22 KUM61079.1 - 2.4e-60 203.7 0.0 2.7e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans_2 PF11951.8 KUM61080.1 - 3e-48 164.6 3.3 3.9e-48 164.2 3.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 KUM61081.1 - 2.4e-48 164.8 0.0 2.9e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KUM61081.1 - 0.00018 20.5 0.1 0.00041 19.4 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.20 KUM61081.1 - 0.0017 18.0 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KUM61081.1 - 0.0023 16.9 0.0 0.003 16.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Ndr PF03096.14 KUM61081.1 - 0.011 14.5 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 Ndr family Thioesterase PF00975.20 KUM61081.1 - 0.037 14.1 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Aldedh PF00171.22 KUM61082.1 - 7e-182 605.1 0.2 7.9e-182 604.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 KUM61082.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family Mpt_N PF09176.11 KUM61082.1 - 0.16 12.1 0.1 0.91 9.7 0.0 2.3 2 0 0 2 2 2 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal TRI5 PF06330.11 KUM61083.1 - 1.7e-86 290.4 0.2 2.2e-86 290.0 0.2 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF1823 PF08853.11 KUM61083.1 - 0.18 12.0 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) DLH PF01738.18 KUM61084.1 - 4.8e-17 62.2 0.0 8.3e-17 61.5 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KUM61084.1 - 0.0091 15.3 0.0 0.041 13.2 0.0 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 KUM61084.1 - 0.067 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal MUG113 PF13455.6 KUM61085.1 - 1.4e-28 99.3 0.3 2.5e-28 98.5 0.3 1.4 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KUM61085.1 - 1.8e-27 95.9 0.1 5.9e-27 94.2 0.1 1.9 1 0 0 1 1 1 1 T5orf172 domain EB PF01683.18 KUM61086.1 - 0.00075 19.7 50.3 0.02 15.2 12.0 5.0 1 1 4 5 5 5 4 EB module Dickkopf_N PF04706.12 KUM61086.1 - 0.031 14.8 45.6 1.4 9.5 4.7 4.5 1 1 2 4 4 4 0 Dickkopf N-terminal cysteine-rich region Toxin_12 PF07740.12 KUM61086.1 - 0.04 14.6 1.5 0.04 14.6 1.5 5.4 5 0 0 5 5 5 0 Ion channel inhibitory toxin DX PF01666.17 KUM61086.1 - 1.9 9.0 47.5 5.4 7.6 3.5 5.3 1 1 4 5 5 5 0 DX module DUF5570 PF17731.1 KUM61086.1 - 6.5 6.9 12.4 1.4 9.0 2.5 3.0 1 1 2 3 3 3 0 Family of unknown function (DUF5570) BUD22 PF09073.10 KUM61088.1 - 0.064 12.6 13.2 0.076 12.3 13.2 1.2 1 0 0 1 1 1 0 BUD22 MFS_1 PF07690.16 KUM61089.1 - 8.6e-45 153.2 68.5 1.9e-37 129.0 42.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.16 KUM61089.1 - 0.86 9.1 3.8 1.2 8.6 0.6 2.9 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Pyr_redox_2 PF07992.14 KUM61090.1 - 4.1e-13 49.2 0.0 3.8e-12 46.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM61090.1 - 1.1e-05 24.9 0.0 0.0016 17.7 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM61090.1 - 6.2e-05 22.3 0.5 0.0001 21.5 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KUM61090.1 - 9e-05 22.6 0.2 0.00022 21.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KUM61090.1 - 0.00029 19.7 0.1 0.0021 16.9 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KUM61090.1 - 0.0011 19.0 0.2 0.83 9.6 0.2 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 KUM61090.1 - 0.0013 18.4 0.3 0.0084 15.7 0.8 2.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KUM61090.1 - 0.0016 17.6 1.4 0.035 13.2 0.9 2.1 1 1 1 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KUM61090.1 - 0.0027 17.0 0.3 0.0042 16.4 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KUM61090.1 - 0.008 15.6 0.1 0.0099 15.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KUM61090.1 - 0.015 14.5 0.0 3.6 6.6 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KUM61090.1 - 0.022 14.0 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KUM61090.1 - 0.26 10.1 0.1 0.38 9.6 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TB2_DP1_HVA22 PF03134.19 KUM61091.1 - 4.2e-24 84.3 5.7 6.8e-24 83.6 5.7 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TANGO2 PF05742.12 KUM61092.1 - 1.3e-74 251.4 0.0 1.5e-74 251.2 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Usp PF00582.26 KUM61093.1 - 2.8e-22 79.7 1.1 8.9e-22 78.1 0.1 2.3 3 1 0 3 3 3 1 Universal stress protein family MIF4G PF02854.19 KUM61094.1 - 9.8e-52 175.7 0.0 1.5e-51 175.1 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KUM61094.1 - 2.9e-19 69.0 0.6 7e-19 67.8 0.6 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 AAA_23 PF13476.6 KUM61094.1 - 8.3 6.9 10.5 8.1 6.9 9.1 1.7 2 0 0 2 2 2 0 AAA domain Cellulase PF00150.18 KUM61095.1 - 1.6e-55 188.5 2.0 2.4e-55 188.0 2.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KUM61095.1 - 6e-14 51.7 11.2 1.8e-13 50.1 11.2 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain p450 PF00067.22 KUM61096.1 - 4e-57 194.0 0.0 5.4e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L7Ae PF01248.26 KUM61098.1 - 4.2e-26 90.5 0.0 5.1e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KUM61098.1 - 0.00013 22.1 0.0 0.00013 22.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KUM61098.1 - 0.005 16.7 0.0 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain BPL_N PF09825.9 KUM61099.1 - 2.1e-147 491.2 0.0 2.5e-147 490.9 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KUM61099.1 - 4.5e-25 88.1 0.0 7e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family CHCH PF06747.13 KUM61100.1 - 3.5e-07 30.2 9.6 4.9e-07 29.7 9.6 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KUM61100.1 - 0.00066 19.6 2.8 0.082 12.9 0.6 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KUM61100.1 - 0.0058 16.6 7.0 0.06 13.4 0.9 1.9 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 KUM61100.1 - 0.049 13.9 4.0 0.071 13.4 4.0 1.3 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX17 PF05051.13 KUM61100.1 - 0.092 13.1 4.5 0.13 12.6 4.5 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Mgm101p PF06420.12 KUM61101.1 - 5.2e-86 286.4 0.0 6.6e-86 286.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 MS_channel PF00924.18 KUM61102.1 - 1.1e-20 74.1 0.6 1.9e-20 73.3 0.6 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KUM61102.1 - 0.0011 18.4 0.3 0.0029 17.0 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KUM61102.1 - 0.0033 17.2 0.2 0.016 15.1 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KUM61102.1 - 0.022 14.2 0.1 0.058 12.9 0.1 1.7 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KUM61102.1 - 0.042 14.3 0.1 0.12 12.9 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair PhyH PF05721.13 KUM61103.1 - 4.1e-26 92.5 0.1 6.4e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) NACHT PF05729.12 KUM61104.1 - 0.041 13.8 0.1 0.13 12.2 0.1 1.9 1 0 0 1 1 1 0 NACHT domain Pox_A_type_inc PF04508.12 KUM61105.1 - 0.0046 16.7 11.0 0.19 11.6 0.1 5.6 6 0 0 6 6 6 2 Viral A-type inclusion protein repeat Filament PF00038.21 KUM61105.1 - 0.0099 15.5 153.7 0.3 10.6 44.2 8.3 2 1 5 8 8 8 6 Intermediate filament protein NmrA PF05368.13 KUM61107.1 - 6.3e-22 78.3 0.0 8.4e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM61107.1 - 2.1e-21 76.6 0.0 2.8e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KUM61107.1 - 1.4e-05 24.7 0.1 7.8e-05 22.2 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KUM61107.1 - 0.00076 19.7 0.0 0.0023 18.2 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KUM61107.1 - 0.024 14.8 0.1 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 KUM61107.1 - 0.043 13.9 0.1 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.12 KUM61107.1 - 0.052 12.7 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.19 KUM61107.1 - 0.15 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Transket_pyr PF02779.24 KUM61108.1 - 1.9e-43 148.2 0.1 4e-43 147.2 0.0 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KUM61108.1 - 2.1e-32 111.6 0.0 5.2e-32 110.3 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KUM61108.1 - 0.072 13.4 0.1 0.35 11.2 0.0 2.0 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II DUF572 PF04502.13 KUM61109.1 - 1.4e-70 238.6 0.2 1.6e-70 238.4 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) IBR PF01485.21 KUM61110.1 - 7e-11 42.2 44.7 2.1e-06 27.8 12.6 3.5 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 KUM61110.1 - 0.00044 20.2 6.6 0.00044 20.2 6.6 4.0 3 1 0 3 3 3 1 zinc-RING finger domain DUF5016 PF16408.5 KUM61110.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5016) PTPA PF03095.15 KUM61112.1 - 1.1e-116 389.5 0.0 1.3e-116 389.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PRA1 PF03208.19 KUM61114.1 - 0.67 9.6 9.5 2.9 7.5 9.5 1.8 1 1 0 1 1 1 0 PRA1 family protein Peptidase_M3 PF01432.20 KUM61115.1 - 3.4e-116 389.2 0.0 5.1e-116 388.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 KUM61115.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Effector protein Phage_Gp17 PF17549.2 KUM61115.1 - 0.1 12.6 0.1 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 Gene Product 17 ApoO PF09769.9 KUM61116.1 - 6.7e-39 132.8 0.1 2.9e-38 130.8 0.1 1.9 2 0 0 2 2 2 1 Apolipoprotein O GRASP55_65 PF04495.14 KUM61117.1 - 2.1e-41 141.5 0.0 2.8e-40 137.8 0.0 2.0 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KUM61117.1 - 0.00099 18.9 0.0 0.34 10.8 0.0 2.8 2 0 0 2 2 2 2 PDZ domain Methyltransf_15 PF09445.10 KUM61118.1 - 2.4e-51 173.6 0.0 3e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 KUM61118.1 - 2.6e-10 40.4 0.0 3.3e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 KUM61118.1 - 1.8e-07 31.0 0.0 2.4e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 KUM61118.1 - 3.7e-06 26.8 0.0 6.7e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 KUM61118.1 - 8.4e-05 22.0 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_31 PF13847.6 KUM61118.1 - 0.00022 21.1 0.0 0.00029 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KUM61118.1 - 0.0015 18.5 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM61118.1 - 0.0073 17.0 0.0 0.013 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 KUM61118.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family Methyltransf_3 PF01596.17 KUM61118.1 - 0.023 13.9 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_11 PF08241.12 KUM61118.1 - 0.029 15.0 0.0 0.056 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain OpuAC PF04069.12 KUM61118.1 - 0.074 12.6 0.1 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system MTS PF05175.14 KUM61118.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain zinc_ribbon_9 PF14369.6 KUM61119.1 - 2.3e-05 24.5 1.3 4.1e-05 23.7 1.3 1.4 1 0 0 1 1 1 1 zinc-ribbon zf-TFIIB PF13453.6 KUM61119.1 - 0.0023 17.2 4.4 0.0082 15.5 0.3 2.5 2 1 1 3 3 3 1 Transcription factor zinc-finger HypA PF01155.19 KUM61119.1 - 0.0098 15.9 0.2 0.016 15.2 0.2 1.2 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 KUM61119.1 - 0.013 14.9 2.3 0.028 13.8 2.3 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zf-C3HC4_3 PF13920.6 KUM61119.1 - 0.031 14.1 0.2 0.061 13.2 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GATA PF00320.27 KUM61119.1 - 0.05 13.2 0.5 0.8 9.4 0.1 2.3 2 0 0 2 2 2 0 GATA zinc finger zf-C2HE PF16278.5 KUM61119.1 - 0.094 13.2 1.2 0.21 12.1 0.0 1.9 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_4 PF13717.6 KUM61119.1 - 0.11 12.4 0.5 7.5 6.6 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KUM61119.1 - 0.17 12.1 1.4 0.58 10.3 1.4 1.9 1 1 1 2 2 2 0 Zinc ribbon domain IMS PF00817.20 KUM61121.1 - 1.9e-42 144.8 0.0 3.3e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 KUM61121.1 - 2.9e-22 78.9 0.1 5.5e-22 78.0 0.1 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 KUM61121.1 - 3.9e-14 53.3 0.0 9.4e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 KUM61121.1 - 2e-12 46.1 16.0 5.6e-07 28.8 4.3 4.3 3 0 0 3 3 3 3 Ubiquitin binding region BRCT_2 PF16589.5 KUM61121.1 - 5.4e-10 39.5 0.0 1.2e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KUM61121.1 - 3.3e-05 24.1 0.0 6.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 KUM61121.1 - 4.6e-05 23.7 0.0 0.00014 22.2 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 KUM61121.1 - 5.5e-05 23.3 0.0 0.00021 21.4 0.0 2.1 1 0 0 1 1 1 1 IMS family HHH motif mCpol PF18182.1 KUM61121.1 - 0.015 15.7 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 minimal CRISPR polymerase domain PTCB-BRCT PF12738.7 KUM61121.1 - 0.02 14.8 0.0 0.063 13.2 0.0 1.9 2 0 0 2 2 2 0 twin BRCT domain AT_hook PF02178.19 KUM61121.1 - 0.053 13.4 3.6 0.27 11.3 3.6 2.3 1 0 0 1 1 1 0 AT hook motif HHH_5 PF14520.6 KUM61121.1 - 0.091 13.4 0.1 0.89 10.2 0.1 2.5 1 1 1 2 2 2 0 Helix-hairpin-helix domain DUF1805 PF08827.11 KUM61121.1 - 0.12 12.8 0.0 0.4 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) MgtE_N PF03448.17 KUM61121.1 - 0.2 12.3 1.3 23 5.7 0.3 3.7 3 0 0 3 3 3 0 MgtE intracellular N domain FKBP_C PF00254.28 KUM61122.1 - 3.7e-32 110.5 0.0 1.4e-31 108.6 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KUM61122.1 - 1.1e-29 103.1 5.2 1.1e-29 103.1 5.2 2.9 2 2 0 2 2 2 1 Nucleoplasmin-like domain Utp14 PF04615.13 KUM61122.1 - 4.9 5.6 48.1 2.6 6.5 26.2 2.1 2 0 0 2 2 2 0 Utp14 protein Zip PF02535.22 KUM61123.1 - 3.7e-54 184.2 0.5 7.7e-54 183.1 0.5 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter HC2 PF07382.11 KUM61124.1 - 0.019 15.1 70.5 0.021 14.9 69.4 1.5 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Fungal_trans PF04082.18 KUM61125.1 - 7.4e-36 123.6 0.0 1.2e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM61125.1 - 3.2e-08 33.6 8.7 5.7e-08 32.7 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HNH_2 PF13391.6 KUM61126.1 - 1.6e-12 47.4 0.0 2.7e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Ketoacyl-synt_C PF02801.22 KUM61128.1 - 0.062 13.3 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain FAD_binding_3 PF01494.19 KUM61129.1 - 7.5e-23 81.3 0.2 1.6e-22 80.3 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KUM61129.1 - 2.6e-05 24.0 6.0 0.0075 15.9 3.8 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KUM61129.1 - 3.2e-05 23.2 4.8 5.7e-05 22.4 4.4 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KUM61129.1 - 4e-05 23.8 0.9 0.00011 22.4 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM61129.1 - 0.00021 20.6 2.7 0.0017 17.7 2.4 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KUM61129.1 - 0.00073 18.7 0.4 0.0021 17.2 0.4 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 KUM61129.1 - 0.0014 19.2 0.3 0.0089 16.6 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KUM61129.1 - 0.0017 17.2 3.0 0.0047 15.7 3.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KUM61129.1 - 0.0032 16.9 0.3 0.0046 16.4 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KUM61129.1 - 0.0097 15.2 4.1 0.28 10.4 4.2 2.2 1 1 0 1 1 1 1 Thi4 family GIDA PF01134.22 KUM61129.1 - 0.025 13.7 3.0 0.044 12.9 2.9 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KUM61129.1 - 0.037 12.9 0.9 0.14 10.9 0.3 2.1 2 1 0 3 3 3 0 Tryptophan halogenase Amino_oxidase PF01593.24 KUM61129.1 - 0.087 12.1 0.7 4.4 6.5 0.2 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KUM61129.1 - 0.64 9.3 3.5 0.2 10.9 0.2 1.8 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Arginosuc_synth PF00764.19 KUM61130.1 - 7e-158 526.0 0.0 8.1e-158 525.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KUM61130.1 - 0.006 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KUM61130.1 - 0.017 13.9 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Pkinase PF00069.25 KUM61131.1 - 9.3e-49 166.2 0.8 2.1e-26 92.9 0.0 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KUM61131.1 - 8.7e-22 77.6 0.0 6.2e-12 45.4 0.0 3.2 2 1 1 3 3 3 3 Protein tyrosine kinase APH PF01636.23 KUM61131.1 - 0.00019 21.4 0.0 0.00042 20.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Orbi_NS1 PF01718.16 KUM61131.1 - 0.058 11.9 0.0 0.093 11.2 0.0 1.2 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein Haspin_kinase PF12330.8 KUM61131.1 - 0.14 11.0 0.1 0.24 10.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KUM61131.1 - 0.15 11.0 0.0 0.42 9.5 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase DUF3591 PF12157.8 KUM61132.1 - 4.9e-175 582.4 0.1 6.5e-175 582.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 KUM61132.1 - 0.0054 16.8 0.7 0.0088 16.1 0.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KUM61132.1 - 0.0072 16.1 1.2 0.016 15.0 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle p450 PF00067.22 KUM61133.1 - 3.2e-72 243.8 0.0 3.8e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BAR PF03114.18 KUM61133.1 - 0.0069 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 BAR domain Ion_trans_2 PF07885.16 KUM61133.1 - 0.035 14.1 1.1 0.084 12.9 1.1 1.6 1 0 0 1 1 1 0 Ion channel Get5_bdg PF16843.5 KUM61133.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein FA_hydroxylase PF04116.13 KUM61135.1 - 0.00015 22.1 0.8 0.00028 21.3 0.8 1.4 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Epimerase PF01370.21 KUM61135.1 - 0.063 12.7 0.1 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KUM61135.1 - 0.078 12.0 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pico_P2A PF00947.19 KUM61135.1 - 0.16 12.0 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Picornavirus core protein 2A RmlD_sub_bind PF04321.17 KUM61135.1 - 0.2 10.7 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 KUM61135.1 - 0.25 10.8 0.4 0.8 9.1 0.2 1.7 1 1 1 2 2 2 0 short chain dehydrogenase Glyco_transf_28 PF03033.20 KUM61136.1 - 1e-22 80.6 0.0 2.8e-22 79.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KUM61136.1 - 6.7e-06 25.2 0.0 1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Fungal_trans_2 PF11951.8 KUM61137.1 - 4.2e-12 45.6 0.2 1.4e-11 43.9 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM61137.1 - 4.2e-09 36.4 8.9 9.8e-09 35.2 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KUM61138.1 - 0.0028 17.1 0.0 0.0028 17.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain eIF-5a PF01287.20 KUM61138.1 - 0.097 12.8 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold MARVEL PF01284.23 KUM61139.1 - 1.2e-08 35.1 12.8 2e-08 34.4 12.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain MpPF26 PF07666.11 KUM61139.1 - 0.066 13.3 0.8 0.16 12.1 0.5 1.7 1 1 1 2 2 2 0 M penetrans paralogue family 26 APG9 PF04109.16 KUM61139.1 - 0.84 8.6 5.7 0.34 9.9 2.7 1.6 1 1 1 2 2 2 0 Autophagy protein Apg9 RTA1 PF04479.13 KUM61140.1 - 4e-56 189.9 8.1 5.5e-56 189.4 8.1 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4131 PF13567.6 KUM61140.1 - 0.44 10.2 8.3 0.26 10.9 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pkinase PF00069.25 KUM61141.1 - 1.3e-12 47.7 0.8 1.3e-11 44.4 0.8 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM61141.1 - 0.00072 18.9 0.1 0.029 13.6 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KUM61141.1 - 0.015 14.1 0.6 0.081 11.7 0.6 1.8 1 1 1 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 KUM61141.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Med13_C PF06333.12 KUM61143.1 - 2.9e-88 296.3 4.0 2.9e-88 296.3 4.0 2.4 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KUM61143.1 - 3.2e-68 230.4 0.5 5.2e-68 229.7 0.5 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KUM61143.1 - 1.1e-34 120.3 0.5 3.9e-20 72.7 0.1 2.8 1 1 1 2 2 2 2 MID domain of medPIWI Rsm1 PF08600.10 KUM61143.1 - 0.086 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Rsm1-like NUC153 PF08159.12 KUM61144.1 - 9.6e-12 44.5 0.8 2e-11 43.5 0.1 2.0 2 0 0 2 2 2 1 NUC153 domain WD40 PF00400.32 KUM61144.1 - 0.012 16.5 0.0 94 4.1 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM61144.1 - 0.11 12.8 0.0 0.64 10.4 0.0 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain 6PGD PF00393.19 KUM61145.1 - 2e-128 427.8 0.0 2.5e-128 427.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KUM61145.1 - 2.4e-50 170.8 0.0 3.4e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KUM61145.1 - 0.082 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PGK PF00162.19 KUM61145.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase RRM_1 PF00076.22 KUM61146.1 - 4.2e-17 61.7 0.0 7e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATG13 PF10033.9 KUM61147.1 - 1.9e-75 253.7 0.0 2.8e-75 253.1 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 LIP PF03583.14 KUM61150.1 - 5e-60 203.3 0.2 7.6e-60 202.7 0.2 1.2 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 KUM61150.1 - 1.3e-05 24.8 0.1 0.16 11.4 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KUM61150.1 - 0.027 14.3 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.18 KUM61150.1 - 0.052 13.1 0.3 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KUM61150.1 - 0.12 11.6 0.0 0.35 10.1 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 RCC1 PF00415.18 KUM61151.1 - 1.7e-25 89.3 0.3 3.6e-06 27.5 0.0 6.7 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KUM61151.1 - 4.6e-14 52.6 0.1 2.6e-11 43.7 0.1 2.6 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.6 KUM61151.1 - 6.1e-12 45.0 5.6 3.3e-08 33.1 0.1 3.2 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 KUM61151.1 - 2.4e-08 34.4 0.2 5.7e-05 23.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM61151.1 - 1.1e-05 25.4 0.2 0.16 12.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KUM61151.1 - 9e-05 23.0 0.0 0.00021 21.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KUM61151.1 - 0.0077 16.5 0.0 0.43 11.0 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Cyt-b5 PF00173.28 KUM61153.1 - 1.6e-24 85.8 0.0 2.1e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YqzH PF14164.6 KUM61153.1 - 0.0074 16.3 0.2 0.014 15.5 0.2 1.4 1 0 0 1 1 1 1 YqzH-like protein KH_1 PF00013.29 KUM61154.1 - 1.4e-91 300.3 23.1 3.3e-12 46.0 0.2 13.4 13 1 0 13 13 13 9 KH domain SLS PF14611.6 KUM61154.1 - 2.6e-13 50.3 4.1 0.74 9.6 0.0 8.9 5 2 4 9 9 9 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KUM61154.1 - 1.1e-11 44.3 23.7 0.0025 17.6 0.2 7.3 6 1 1 7 7 7 5 KH domain KH_4 PF13083.6 KUM61154.1 - 0.0022 17.8 7.2 11 5.9 0.1 5.4 5 0 0 5 5 5 3 KH domain RL10P_insert PF17777.1 KUM61154.1 - 0.039 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Insertion domain in 60S ribosomal protein L10P LeuA_dimer PF08502.10 KUM61154.1 - 0.055 13.4 0.2 5 7.0 0.0 3.2 3 0 0 3 3 3 0 LeuA allosteric (dimerisation) domain BMC PF00936.19 KUM61154.1 - 0.074 13.1 1.7 17 5.5 0.1 4.3 6 0 0 6 6 6 0 BMC domain Acylphosphatase PF00708.18 KUM61154.1 - 0.16 12.4 1.6 3.6 8.1 0.2 3.5 3 0 0 3 3 3 0 Acylphosphatase KH_5 PF13184.6 KUM61154.1 - 0.2 11.8 10.7 45 4.2 0.1 6.3 7 0 0 7 7 7 0 NusA-like KH domain VHS PF00790.19 KUM61155.1 - 7.9e-40 136.0 0.8 7.8e-39 132.7 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KUM61155.1 - 5.3e-16 58.5 2.3 8.5e-16 57.9 2.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger GAT PF03127.14 KUM61155.1 - 1.6e-05 25.1 0.1 4.8e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 KUM61155.1 - 9e-05 22.1 20.1 0.012 15.5 2.9 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 KUM61155.1 - 0.061 13.5 0.3 0.12 12.6 0.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Npa1 PF11707.8 KUM61155.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal DZR PF12773.7 KUM61155.1 - 0.22 11.6 2.4 0.48 10.5 2.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KUM61155.1 - 0.26 11.2 2.0 0.81 9.7 2.0 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain UCH PF00443.29 KUM61156.1 - 7.9e-51 173.0 0.0 1.1e-50 172.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KUM61156.1 - 2e-16 60.5 0.4 2.7e-13 50.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 KUM61156.1 - 2.5e-06 27.6 0.0 7.8e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.20 KUM61156.1 - 1.7e-05 25.3 0.0 3.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Sec10 PF07393.11 KUM61157.1 - 1.6e-230 767.4 0.0 1.8e-230 767.1 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Phage_min_cap2 PF06152.11 KUM61157.1 - 0.034 13.0 0.1 5.6 5.8 0.0 2.3 2 0 0 2 2 2 0 Phage minor capsid protein 2 Tropomyosin PF00261.20 KUM61157.1 - 0.037 13.4 0.1 0.12 11.8 0.1 1.8 1 0 0 1 1 1 0 Tropomyosin Baculo_PEP_C PF04513.12 KUM61157.1 - 0.14 12.2 5.0 1.9 8.5 0.6 3.2 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ELMO_CED12 PF04727.13 KUM61159.1 - 1e-48 165.8 0.1 1.7e-48 165.0 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KUM61159.1 - 1.8e-32 112.7 0.1 6.1e-32 111.0 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 KUM61159.1 - 1.7e-15 57.3 0.0 4.3e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) DUF1752 PF08550.10 KUM61160.1 - 6e-12 45.2 5.6 1.3e-11 44.1 5.6 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF3752 PF12572.8 KUM61161.1 - 6.4e-39 133.9 11.5 6.4e-39 133.9 11.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) RXT2_N PF08595.11 KUM61161.1 - 2.2 8.3 8.7 0.67 10.0 1.5 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal GCIP PF13324.6 KUM61161.1 - 7.7 6.0 9.0 5.8 6.5 2.1 2.2 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Peptidase_M75 PF09375.10 KUM61162.1 - 0.14 11.6 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 Imelysin A_deaminase PF00962.22 KUM61163.1 - 1.5e-122 409.0 0.0 2e-122 408.6 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase SH3_1 PF00018.28 KUM61165.1 - 1.6e-24 85.3 5.9 2.2e-12 46.4 0.6 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KUM61165.1 - 7.8e-24 83.3 6.2 2.3e-12 46.6 0.7 2.4 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 KUM61165.1 - 3e-15 56.1 0.0 5.9e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 KUM61165.1 - 7e-15 54.4 1.0 2e-06 27.4 0.1 3.0 3 0 0 3 3 3 2 Variant SH3 domain Dynamin_M PF01031.20 KUM61166.1 - 6.5e-111 370.1 0.0 1.1e-110 369.4 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KUM61166.1 - 1.1e-54 185.0 0.0 2.1e-54 184.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KUM61166.1 - 1.6e-31 108.3 0.6 1.6e-31 108.3 0.6 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KUM61166.1 - 0.00022 21.3 0.3 0.0021 18.1 0.3 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KUM61166.1 - 0.026 14.1 0.1 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B UAA PF08449.11 KUM61167.1 - 2.4e-87 292.9 5.7 4.3e-87 292.1 5.7 1.3 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KUM61167.1 - 0.00026 20.2 0.3 0.00026 20.2 0.3 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.20 KUM61167.1 - 0.24 11.6 23.7 0.58 10.3 7.7 3.6 3 1 0 3 3 3 0 EamA-like transporter family Rad17 PF03215.15 KUM61168.1 - 4.3e-27 95.3 0.0 7.3e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KUM61168.1 - 1.9e-05 25.1 0.0 5.6e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KUM61168.1 - 0.0011 19.4 0.0 0.0028 18.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KUM61168.1 - 0.011 16.0 0.0 0.039 14.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KUM61168.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KUM61168.1 - 0.021 15.4 0.0 0.063 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KUM61168.1 - 0.069 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 KUM61168.1 - 0.089 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KUM61168.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase TsaE PF02367.17 KUM61168.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ank_2 PF12796.7 KUM61169.1 - 7.4e-25 87.4 0.9 1.6e-07 31.8 0.0 6.7 5 2 1 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM61169.1 - 2e-20 72.9 3.8 0.0012 19.3 0.0 7.9 5 2 1 8 8 8 4 Ankyrin repeats (many copies) Pkinase PF00069.25 KUM61169.1 - 7e-20 71.5 0.0 1.1e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM61169.1 - 2.9e-17 62.8 0.0 5e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 KUM61169.1 - 1.2e-16 59.1 7.2 0.0041 17.5 0.1 10.3 11 0 0 11 11 11 2 Ankyrin repeat Ank_5 PF13857.6 KUM61169.1 - 3.6e-13 49.4 4.1 0.019 15.3 0.0 7.5 5 3 3 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 KUM61169.1 - 2e-12 46.9 15.0 0.26 11.8 0.0 10.7 10 1 0 10 10 10 4 Ankyrin repeat Ribonucleas_3_2 PF11469.8 KUM61169.1 - 0.17 12.3 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease III Mannosyl_trans4 PF15971.5 KUM61169.1 - 0.19 11.6 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 DolP-mannose mannosyltransferase HeLo PF14479.6 KUM61171.1 - 8.4e-10 38.8 0.4 1.6e-09 37.9 0.4 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 KUM61171.1 - 0.00047 19.5 0.0 0.0014 18.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KUM61171.1 - 0.0072 15.7 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Glyco_tranf_2_3 PF13641.6 KUM61172.1 - 5.1e-25 88.7 0.0 8.1e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KUM61172.1 - 3.2e-11 43.5 0.5 3.2e-11 43.5 0.5 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KUM61172.1 - 0.0073 16.1 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KUM61172.1 - 0.009 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Sortilin-Vps10 PF15902.5 KUM61174.1 - 3e-276 916.2 6.6 8.5e-141 469.8 1.6 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KUM61174.1 - 5.8e-92 306.6 15.4 3.7e-47 160.8 1.1 2.6 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KUM61174.1 - 3.3e-07 29.3 36.6 0.94 9.7 0.3 11.1 12 0 0 12 12 12 5 BNR/Asp-box repeat BNR_2 PF13088.6 KUM61174.1 - 0.0012 18.2 1.7 35 3.6 0.0 5.1 5 0 0 5 5 5 0 BNR repeat-like domain Mo-co_dimer PF03404.16 KUM61174.1 - 0.0068 16.4 0.1 12 5.9 0.0 4.5 4 0 0 4 4 4 1 Mo-co oxidoreductase dimerisation domain DUF2167 PF09935.9 KUM61174.1 - 0.018 14.3 0.2 0.042 13.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) dCMP_cyt_deam_1 PF00383.23 KUM61175.1 - 5.6e-15 55.1 0.1 6.6e-15 54.8 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KUM61175.1 - 1.8e-08 34.7 1.2 9e-07 29.2 0.2 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KUM61175.1 - 0.0001 22.0 0.7 0.26 10.9 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases NmrA PF05368.13 KUM61176.1 - 6.3e-38 130.6 0.1 8.1e-38 130.3 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM61176.1 - 1.9e-16 60.5 0.0 2.4e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KUM61176.1 - 5.3e-06 26.1 0.0 9.3e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KUM61176.1 - 0.0008 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KUM61176.1 - 0.00082 18.9 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KUM61176.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 KUM61176.1 - 0.021 13.8 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KUM61176.1 - 0.038 13.2 0.1 0.14 11.3 0.0 1.8 1 1 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.15 KUM61176.1 - 0.081 12.0 0.0 0.44 9.6 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KUM61176.1 - 0.082 13.4 0.1 0.24 11.8 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KUM61176.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Fungal_trans PF04082.18 KUM61177.1 - 2e-13 50.0 0.3 2.6e-13 49.6 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mito_carr PF00153.27 KUM61178.1 - 1.7e-65 217.0 0.7 5.2e-21 74.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KUM61178.1 - 0.11 11.6 1.3 4.2 6.4 0.0 3.1 3 1 0 4 4 4 0 Gammaproteobacterial serine protease Antimicrobial_6 PF08036.11 KUM61178.1 - 0.94 9.6 2.9 7.3 6.8 0.2 2.6 2 0 0 2 2 2 0 Diapausin family of antimicrobial peptide Cgr1 PF03879.14 KUM61179.1 - 7.6e-33 113.1 24.5 8.5e-33 113.0 24.5 1.0 1 0 0 1 1 1 1 Cgr1 family N2227 PF07942.12 KUM61179.1 - 0.24 10.6 1.6 0.28 10.3 1.6 1.2 1 0 0 1 1 1 0 N2227-like protein DUF4192 PF13830.6 KUM61179.1 - 0.3 11.1 4.8 0.32 11.0 4.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) GAS PF13851.6 KUM61180.1 - 0.00024 20.5 2.7 0.00043 19.7 2.7 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KUM61180.1 - 0.0035 16.3 1.9 0.005 15.8 1.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.6 KUM61180.1 - 0.0085 14.8 1.4 0.012 14.3 1.4 1.1 1 0 0 1 1 1 1 AAA domain MCU PF04678.13 KUM61180.1 - 0.013 15.6 0.2 0.024 14.7 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Baculo_PEP_C PF04513.12 KUM61180.1 - 0.015 15.3 1.2 0.18 11.8 1.5 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus T3SSipB PF16535.5 KUM61180.1 - 0.016 15.7 0.6 0.03 14.8 0.6 1.4 1 0 0 1 1 1 0 Type III cell invasion protein SipB EMP24_GP25L PF01105.24 KUM61180.1 - 0.029 14.3 0.6 0.047 13.6 0.6 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD LMBR1 PF04791.16 KUM61180.1 - 0.032 13.2 0.4 0.044 12.7 0.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CENP-F_leu_zip PF10473.9 KUM61180.1 - 0.035 14.1 3.1 0.068 13.2 3.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KUM61180.1 - 0.051 13.6 0.3 0.53 10.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 KUM61180.1 - 0.053 13.4 4.6 0.35 10.7 4.6 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Csm1_N PF18504.1 KUM61180.1 - 0.064 13.6 3.1 0.88 10.0 0.7 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Occludin_ELL PF07303.13 KUM61180.1 - 0.1 13.3 0.6 0.63 10.8 0.5 2.3 1 1 0 1 1 1 0 Occludin homology domain THOC7 PF05615.13 KUM61180.1 - 0.17 12.2 4.6 0.33 11.2 4.6 1.6 1 0 0 1 1 1 0 Tho complex subunit 7 DUF3552 PF12072.8 KUM61180.1 - 0.19 11.1 3.1 0.36 10.2 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Fib_alpha PF08702.10 KUM61180.1 - 0.25 11.5 1.5 0.44 10.7 1.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family JIP_LZII PF16471.5 KUM61180.1 - 0.34 11.1 2.8 2 8.6 1.2 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Laminin_II PF06009.12 KUM61180.1 - 0.4 10.7 1.7 1.2 9.2 0.6 2.0 1 1 1 2 2 2 0 Laminin Domain II Snapin_Pallidin PF14712.6 KUM61180.1 - 0.5 10.8 4.4 0.18 12.2 1.5 1.8 2 0 0 2 2 1 0 Snapin/Pallidin DUF16 PF01519.16 KUM61180.1 - 0.54 10.8 3.7 0.36 11.3 1.8 1.6 2 0 0 2 2 1 0 Protein of unknown function DUF16 ZapB PF06005.12 KUM61180.1 - 1 9.8 7.2 14 6.2 0.0 2.6 1 1 1 2 2 2 0 Cell division protein ZapB SUI1 PF01253.22 KUM61181.1 - 3.8e-23 81.8 0.3 6.7e-23 81.0 0.3 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cytochrom_C1 PF02167.15 KUM61182.1 - 9.7e-91 303.4 0.0 1.2e-90 303.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KUM61182.1 - 0.0051 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KUM61182.1 - 0.14 13.3 0.8 0.75 11.0 0.2 2.5 3 1 0 3 3 3 0 Cytochrome c hDGE_amylase PF14701.6 KUM61183.1 - 2.2e-183 610.3 0.0 2.8e-183 610.0 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KUM61183.1 - 5e-117 391.1 0.0 8.3e-117 390.4 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KUM61183.1 - 1.6e-84 283.6 0.0 2.2e-84 283.1 0.0 1.2 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KUM61183.1 - 1.9e-29 101.6 0.0 4.1e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KUM61183.1 - 0.0055 16.3 0.5 0.024 14.2 0.5 2.1 2 1 0 2 2 2 1 Alpha amylase, catalytic domain NAD_Gly3P_dh_N PF01210.23 KUM61184.1 - 7.3e-46 156.0 0.4 1.2e-45 155.3 0.1 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KUM61184.1 - 5.4e-41 140.2 0.1 9.1e-41 139.5 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F-box PF00646.33 KUM61185.1 - 5.9e-07 29.2 0.1 1.9e-06 27.6 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KUM61185.1 - 8.2e-07 28.8 1.4 8.2e-07 28.8 1.4 2.3 2 0 0 2 2 2 1 F-box-like PPR_3 PF13812.6 KUM61185.1 - 0.19 11.8 0.0 0.58 10.3 0.0 1.7 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Sec10 PF07393.11 KUM61186.1 - 2.9e-181 604.5 3.0 3.7e-181 604.2 3.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KUM61186.1 - 1.6e-05 24.7 0.0 3.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KUM61186.1 - 0.0017 18.2 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain Brix PF04427.18 KUM61187.1 - 5e-30 105.0 0.0 6.8e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain F-box-like PF12937.7 KUM61188.1 - 7.2e-06 25.8 0.8 9.9e-05 22.2 1.4 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KUM61188.1 - 0.0038 17.1 4.4 0.013 15.4 4.4 2.0 1 0 0 1 1 1 1 F-box domain CPL PF08144.11 KUM61188.1 - 0.049 14.0 0.0 0.085 13.2 0.0 1.3 1 0 0 1 1 1 0 CPL (NUC119) domain PfkB PF00294.24 KUM61189.1 - 8.8e-17 61.3 0.0 2.5e-16 59.9 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase SLX9 PF15341.6 KUM61190.1 - 3.3e-33 114.9 11.9 4.1e-33 114.6 11.9 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Neugrin PF06413.11 KUM61190.1 - 0.0028 17.7 1.7 0.0037 17.3 1.7 1.2 1 0 0 1 1 1 1 Neugrin Peptidase_A2E PF12382.8 KUM61190.1 - 0.059 13.4 0.2 0.089 12.8 0.2 1.2 1 0 0 1 1 1 0 Retrotransposon peptidase F-box-like PF12937.7 KUM61191.1 - 2e-06 27.6 0.1 5.5e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KUM61191.1 - 0.017 15.0 0.0 0.073 13.0 0.0 2.1 1 0 0 1 1 1 0 F-box domain ExoD PF06055.12 KUM61191.1 - 0.51 9.7 1.4 0.63 9.4 0.2 1.7 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD RSN1_7TM PF02714.15 KUM61192.1 - 3.5e-80 269.2 20.8 3.5e-80 269.2 20.8 1.8 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KUM61192.1 - 1.3e-40 139.5 0.0 1.9e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KUM61192.1 - 6e-40 136.5 0.3 6e-40 136.5 0.3 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport Anoctamin PF04547.12 KUM61192.1 - 0.0036 16.2 1.9 0.0036 16.2 1.9 2.2 3 0 0 3 3 3 1 Calcium-activated chloride channel DAHP_synth_1 PF00793.20 KUM61193.1 - 4.4e-102 340.6 0.0 5.5e-102 340.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF5590 PF17881.1 KUM61193.1 - 0.03 14.4 0.1 0.093 12.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5590) AIG2_2 PF13772.6 KUM61194.1 - 0.00081 19.7 0.1 0.016 15.6 0.0 2.7 3 0 0 3 3 3 1 AIG2-like family PsbJ PF01788.17 KUM61194.1 - 0.04 13.8 0.2 0.081 12.8 0.2 1.5 1 0 0 1 1 1 0 PsbJ SIKE PF05769.11 KUM61195.1 - 0.079 12.9 2.8 0.14 12.1 2.8 1.3 1 0 0 1 1 1 0 SIKE family Glypican PF01153.19 KUM61195.1 - 7.3 5.3 6.7 0.48 9.2 0.9 1.8 2 0 0 2 2 2 0 Glypican AAA_2 PF07724.14 KUM61196.1 - 5.1e-36 124.3 0.0 5.3e-35 121.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KUM61196.1 - 1.6e-14 54.5 0.0 3.9e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KUM61196.1 - 3.8e-07 30.1 0.0 9.3e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KUM61196.1 - 2.9e-06 27.3 0.0 6.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KUM61196.1 - 0.00015 21.5 0.0 0.041 13.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KUM61196.1 - 0.00026 20.5 0.2 0.016 14.6 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KUM61196.1 - 0.00092 19.0 0.1 0.02 14.6 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KUM61196.1 - 0.0013 19.0 0.6 0.029 14.6 0.6 2.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KUM61196.1 - 0.0067 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KUM61196.1 - 0.0067 16.2 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 KUM61196.1 - 0.0099 16.3 4.4 0.016 15.6 0.1 2.9 2 1 2 4 4 3 1 AAA ATPase domain AAA_18 PF13238.6 KUM61196.1 - 0.018 15.6 0.0 0.047 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KUM61196.1 - 0.023 14.8 0.0 0.09 12.9 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KUM61196.1 - 0.034 13.7 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KUM61196.1 - 0.055 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KUM61196.1 - 0.058 13.3 0.2 0.94 9.4 0.2 2.4 1 1 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KUM61196.1 - 0.064 13.4 0.3 0.86 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 KUM61196.1 - 0.064 12.3 0.1 0.15 11.1 0.1 1.5 1 0 0 1 1 1 0 MCM P-loop domain TsaE PF02367.17 KUM61196.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KUM61196.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain CAP PF00188.26 KUM61197.1 - 7.7e-21 75.2 6.0 7.7e-21 75.2 6.0 2.1 2 1 0 2 2 2 1 Cysteine-rich secretory protein family DUF515 PF04415.12 KUM61197.1 - 2 6.7 4.0 2.8 6.2 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) eIF2A PF08662.11 KUM61198.1 - 5.6e-37 127.5 6.9 6.2e-34 117.6 4.8 4.0 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KUM61198.1 - 3.7e-06 26.7 0.0 7.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KUM61198.1 - 0.027 15.3 0.8 5.8 8.0 0.1 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat WD40 PF00400.32 KUM61199.1 - 2.3e-60 199.1 27.5 8.6e-11 42.2 0.1 9.1 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM61199.1 - 9.9e-18 64.2 6.1 0.00075 19.7 0.1 6.2 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KUM61199.1 - 2e-08 34.3 0.2 0.011 15.6 0.0 3.5 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KUM61199.1 - 1.5e-07 30.7 0.9 0.083 11.8 0.0 5.1 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KUM61199.1 - 2.1e-05 23.4 6.4 0.49 9.0 0.1 5.3 4 2 0 5 5 5 2 Nucleoporin Nup120/160 NLE PF08154.12 KUM61199.1 - 3.4e-05 24.3 0.0 7.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40_like PF17005.5 KUM61199.1 - 0.0023 17.3 0.0 3.1 7.0 0.0 3.6 5 0 0 5 5 5 1 WD40-like domain FAD_binding_9 PF08021.11 KUM61199.1 - 0.012 15.8 0.1 0.11 12.7 0.0 2.4 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain DUF4550 PF15084.6 KUM61199.1 - 0.026 14.9 0.0 0.3 11.5 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4550) 120_Rick_ant PF12574.8 KUM61199.1 - 0.081 12.1 0.4 0.45 9.7 0.0 2.1 2 0 0 2 2 2 0 120 KDa Rickettsia surface antigen PALB2_WD40 PF16756.5 KUM61199.1 - 0.22 10.4 4.1 12 4.7 0.0 3.9 3 2 2 5 5 5 0 Partner and localizer of BRCA2 WD40 domain Velvet PF11754.8 KUM61202.1 - 3.5e-89 299.0 0.0 2e-88 296.6 0.0 1.8 1 1 0 1 1 1 1 Velvet factor DUF2076 PF09849.9 KUM61202.1 - 7.8 6.5 6.5 12 5.8 6.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SWIB PF02201.18 KUM61203.1 - 6.4e-30 102.9 0.1 1.4e-29 101.8 0.1 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KUM61203.1 - 3.4e-14 52.5 0.9 6.3e-14 51.6 0.9 1.5 1 0 0 1 1 1 1 DEK C terminal domain zf-C3HC4_3 PF13920.6 KUM61204.1 - 3e-07 30.2 8.7 3e-07 30.2 8.7 3.6 3 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KUM61204.1 - 0.0048 16.7 10.3 0.0048 16.7 10.3 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) MutS_V PF00488.21 KUM61205.1 - 3.1e-63 213.2 0.1 4.6e-63 212.6 0.1 1.2 1 0 0 1 1 1 1 MutS domain V MutS_IV PF05190.18 KUM61205.1 - 3.2e-05 24.2 0.0 6.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_III PF05192.18 KUM61205.1 - 3.8e-05 24.0 0.6 0.00011 22.5 0.1 1.9 2 1 0 2 2 2 1 MutS domain III AAA_30 PF13604.6 KUM61205.1 - 0.00068 19.4 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 KUM61205.1 - 0.019 14.4 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein DUF4392 PF14336.6 KUM61205.1 - 0.097 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) MutS_III PF05192.18 KUM61206.1 - 1.8e-24 87.0 0.3 2.4e-24 86.6 0.3 1.1 1 0 0 1 1 1 1 MutS domain III Ras PF00071.22 KUM61207.1 - 1.9e-63 212.9 0.2 2.2e-63 212.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM61207.1 - 1e-35 122.5 0.2 1.4e-35 122.1 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM61207.1 - 2.8e-13 49.7 0.1 3.7e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KUM61207.1 - 5.1e-08 33.0 0.1 7.5e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KUM61207.1 - 0.00011 22.1 0.1 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KUM61207.1 - 0.00036 20.0 0.1 0.00056 19.3 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KUM61207.1 - 0.00045 19.8 0.1 0.002 17.7 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KUM61207.1 - 0.0024 18.1 0.1 0.018 15.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KUM61207.1 - 0.0099 15.9 0.2 0.03 14.3 0.1 1.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KUM61207.1 - 0.012 16.0 0.0 0.018 15.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 KUM61207.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KUM61207.1 - 0.02 15.4 0.1 0.03 14.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KUM61207.1 - 0.03 14.1 0.1 0.063 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KUM61207.1 - 0.047 13.1 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 KUM61207.1 - 0.056 13.3 0.6 0.08 12.7 0.5 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 KUM61207.1 - 0.071 12.6 0.1 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AEP1 PF17049.5 KUM61207.1 - 0.1 11.7 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 MCM PF00493.23 KUM61207.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 KUM61207.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Chromo PF00385.24 KUM61208.1 - 7.1e-06 25.8 2.7 1.6e-05 24.7 2.7 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HRXXH PF13933.6 KUM61209.1 - 8.4e-111 369.4 0.0 1.2e-110 368.9 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 KUM61209.1 - 0.00083 19.9 0.1 0.002 18.7 0.1 1.7 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Zip PF02535.22 KUM61210.1 - 1.9e-38 132.6 14.3 1.9e-38 132.6 14.3 2.0 2 0 0 2 2 2 1 ZIP Zinc transporter Acetyltransf_10 PF13673.7 KUM61211.1 - 3.3e-09 36.7 0.0 4.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM61211.1 - 3.3e-08 33.8 0.0 4.4e-08 33.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KUM61211.1 - 4.6e-08 33.4 0.0 7.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KUM61211.1 - 6.7e-07 29.4 0.1 0.00031 20.8 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KUM61211.1 - 0.0012 18.8 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KUM61211.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase WD40 PF00400.32 KUM61213.1 - 2.4e-19 69.3 12.9 8e-05 23.3 0.8 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM61213.1 - 4.9e-08 33.2 0.0 0.085 13.2 0.0 4.6 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Trypan_PARP PF05887.11 KUM61215.1 - 0.00063 19.7 94.9 0.014 15.4 22.8 5.2 3 2 1 5 5 5 4 Procyclic acidic repetitive protein (PARP) MFS_1 PF07690.16 KUM61218.1 - 8.4e-32 110.4 40.9 8.4e-32 110.4 40.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM61218.1 - 1.1e-08 34.4 37.0 1.6e-07 30.6 11.6 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter SHR3_chaperone PF08229.11 KUM61219.1 - 2.2e-79 264.8 0.0 2.6e-79 264.6 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5453 PF17534.2 KUM61219.1 - 0.041 13.8 0.1 0.086 12.8 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5453) Arrestin_N PF00339.29 KUM61220.1 - 1.9e-14 53.9 0.0 1.2e-13 51.4 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KUM61220.1 - 8.7e-09 35.9 0.0 1.5e-05 25.5 0.0 2.8 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain SAM_2 PF07647.17 KUM61223.1 - 1.3e-11 44.4 0.1 2.4e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KUM61223.1 - 2.8e-09 37.3 0.2 9.9e-09 35.5 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 KUM61223.1 - 6.2e-06 26.7 0.0 1.5e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KUM61223.1 - 0.2 12.1 0.6 0.45 10.9 0.6 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain Fungal_trans_2 PF11951.8 KUM61224.1 - 1.4e-83 280.9 0.0 1.8e-83 280.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM61224.1 - 1.3e-07 31.6 8.5 2.1e-07 30.9 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APG5 PF04106.12 KUM61226.1 - 1.3e-62 211.4 0.0 1.6e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Mnd1 PF03962.15 KUM61227.1 - 4.4e-22 78.1 0.0 6.6e-21 74.4 0.0 2.3 2 0 0 2 2 2 1 Mnd1 HTH domain DUF4763 PF15960.5 KUM61227.1 - 0.013 14.8 1.4 0.016 14.5 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) APG6_N PF17675.1 KUM61227.1 - 0.019 15.5 6.8 0.044 14.3 6.8 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region LZ3wCH PF18517.1 KUM61227.1 - 0.032 14.3 0.3 0.084 13.0 0.0 1.9 2 0 0 2 2 2 0 Leucine zipper with capping helix domain E1_UFD PF09358.10 KUM61227.1 - 0.052 14.3 0.0 0.1 13.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin fold domain ZapB PF06005.12 KUM61227.1 - 0.35 11.3 6.5 0.085 13.3 1.9 2.3 1 1 1 2 2 2 0 Cell division protein ZapB UAF_Rrn10 PF05234.11 KUM61228.1 - 0.00051 20.3 0.0 0.00085 19.6 0.0 1.4 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Abhydrolase_6 PF12697.7 KUM61229.1 - 7.8e-11 43.0 0.0 1.4e-10 42.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM61229.1 - 3.5e-09 36.7 1.2 1.5e-08 34.6 1.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM61229.1 - 4e-09 36.1 0.0 1.1e-08 34.6 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 KUM61229.1 - 0.00045 19.8 0.1 0.4 10.2 0.0 3.1 2 1 1 3 3 3 2 Dienelactone hydrolase family DUF2048 PF09752.9 KUM61229.1 - 0.013 14.7 0.3 0.027 13.6 0.3 1.4 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Lipase_3 PF01764.25 KUM61229.1 - 0.1 12.5 0.6 0.27 11.1 0.3 1.8 2 0 0 2 2 2 0 Lipase (class 3) Toxin_GhoT_OrtT PF10753.9 KUM61231.1 - 0.068 13.4 1.5 0.26 11.5 1.5 2.0 1 0 0 1 1 1 0 Toxin GhoT_OrtT Sugar_tr PF00083.24 KUM61233.1 - 6e-133 444.0 23.4 6.9e-133 443.8 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM61233.1 - 6.9e-25 87.7 39.4 1.2e-19 70.5 15.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRP PF06011.12 KUM61234.1 - 1.7e-132 442.2 24.3 2e-132 442.0 24.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KUM61234.1 - 2.5e-33 115.4 0.1 3.7e-33 114.8 0.1 1.3 1 0 0 1 1 1 1 ML-like domain DUF5472 PF17566.2 KUM61234.1 - 0.64 10.0 7.4 0.11 12.5 0.9 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5472) Methyltransf_25 PF13649.6 KUM61235.1 - 2e-09 38.0 0.0 3.6e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM61235.1 - 8.7e-07 29.5 0.0 1.6e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM61235.1 - 8.9e-05 22.4 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM61235.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KUM61235.1 - 0.0045 16.8 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Sema PF01403.19 KUM61235.1 - 0.23 10.2 0.0 0.32 9.8 0.0 1.1 1 0 0 1 1 1 0 Sema domain Complex1_LYR_2 PF13233.6 KUM61236.1 - 3.5e-06 27.7 0.1 5.5e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KUM61236.1 - 3.6e-05 23.7 0.4 5.1e-05 23.2 0.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) 4HBT_2 PF13279.6 KUM61237.1 - 2.5e-09 37.7 0.0 3.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4080 PF13311.6 KUM61237.1 - 0.081 13.1 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) PhoD PF09423.10 KUM61238.1 - 2.9e-06 26.6 0.0 0.00029 20.0 0.0 2.6 1 1 0 1 1 1 1 PhoD-like phosphatase Pyr_redox_2 PF07992.14 KUM61239.1 - 1.4e-48 165.6 0.2 1.7e-48 165.4 0.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM61239.1 - 3.6e-18 65.9 0.1 6e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM61239.1 - 6.7e-15 55.4 0.1 7.9e-13 48.8 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM61239.1 - 6e-05 23.2 0.4 0.067 13.4 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KUM61239.1 - 0.00022 21.6 0.2 0.024 15.1 0.0 3.1 2 2 1 3 3 3 1 Putative NAD(P)-binding Thi4 PF01946.17 KUM61239.1 - 0.00038 19.8 1.6 0.002 17.4 0.1 2.4 2 1 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KUM61239.1 - 0.0034 16.6 0.3 0.32 10.1 0.0 3.1 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KUM61239.1 - 0.018 14.3 1.6 6.1 6.0 0.0 2.9 2 1 1 3 3 3 0 FAD binding domain FAD_oxidored PF12831.7 KUM61239.1 - 0.018 14.4 0.3 0.18 11.1 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KUM61239.1 - 0.028 13.5 3.1 6.1 5.8 0.1 3.7 4 1 1 5 5 5 0 Glucose inhibited division protein A DAO PF01266.24 KUM61239.1 - 0.047 13.3 4.0 1.9 8.0 0.0 3.6 2 2 1 4 4 4 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KUM61239.1 - 0.11 12.5 0.3 46 4.1 0.0 3.1 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KUM61239.1 - 0.27 10.3 4.9 0.85 8.6 0.3 3.4 3 1 0 4 4 4 0 FAD binding domain Dynamitin PF04912.14 KUM61240.1 - 4.4e-74 250.2 10.9 7.2e-73 246.1 10.9 2.0 1 1 0 1 1 1 1 Dynamitin Jnk-SapK_ap_N PF09744.9 KUM61240.1 - 4.6e-05 23.7 7.7 0.011 16.0 0.2 2.9 3 0 0 3 3 3 2 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 KUM61240.1 - 0.012 15.6 0.1 0.23 11.5 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KUM61240.1 - 0.016 15.3 1.5 0.016 15.3 1.5 4.0 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein Fmp27_WPPW PF10359.9 KUM61240.1 - 0.021 13.7 0.9 3.4 6.4 0.2 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DHR10 PF18595.1 KUM61240.1 - 0.021 14.9 0.2 0.021 14.9 0.2 3.4 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain FapA PF03961.13 KUM61240.1 - 0.022 13.4 0.0 0.18 10.4 0.0 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A CCDC32 PF14989.6 KUM61240.1 - 0.065 13.2 1.0 0.88 9.6 0.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing 32 SlyX PF04102.12 KUM61240.1 - 0.068 13.8 5.1 2 9.1 0.2 4.4 5 1 1 6 6 6 0 SlyX Laminin_II PF06009.12 KUM61240.1 - 0.082 12.9 5.3 0.11 12.5 0.0 3.2 3 1 1 4 4 4 0 Laminin Domain II Spectrin PF00435.21 KUM61240.1 - 0.097 13.2 4.3 0.93 10.0 0.4 3.2 3 0 0 3 3 3 0 Spectrin repeat Prefoldin_2 PF01920.20 KUM61240.1 - 0.1 12.6 4.7 0.4 10.7 0.5 2.8 3 0 0 3 3 3 0 Prefoldin subunit Cnn_1N PF07989.11 KUM61240.1 - 0.16 12.1 1.4 10 6.4 0.1 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF4407 PF14362.6 KUM61240.1 - 0.2 11.0 14.6 0.044 13.1 4.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KUM61240.1 - 0.21 10.5 6.8 0.26 10.1 0.2 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF4200 PF13863.6 KUM61240.1 - 0.26 11.7 3.4 1 9.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) MbeD_MobD PF04899.12 KUM61240.1 - 0.37 11.0 4.1 1.9 8.7 0.4 3.3 4 0 0 4 4 3 0 MbeD/MobD like Spc24 PF08286.11 KUM61240.1 - 0.37 11.1 7.3 0.64 10.3 0.2 3.2 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 DUF2203 PF09969.9 KUM61240.1 - 0.4 11.4 6.3 2.1 9.1 0.2 3.3 2 2 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Golgin_A5 PF09787.9 KUM61240.1 - 0.43 10.0 4.7 1.4 8.3 0.2 2.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 Prefoldin PF02996.17 KUM61240.1 - 0.44 10.5 5.5 0.37 10.7 0.3 3.0 3 1 0 3 3 2 0 Prefoldin subunit DUF4618 PF15397.6 KUM61240.1 - 0.46 9.9 1.8 14 5.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DivIC PF04977.15 KUM61240.1 - 0.71 9.7 8.6 1.5 8.7 0.1 3.6 3 2 0 3 3 3 0 Septum formation initiator Rho_Binding PF08912.11 KUM61240.1 - 0.74 10.7 2.8 3.6 8.5 0.2 2.9 3 0 0 3 3 3 0 Rho Binding Glyco_transf_22 PF03901.17 KUM61241.1 - 1.7e-39 136.3 13.8 2e-39 136.0 13.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF1772 PF08592.11 KUM61241.1 - 0.0021 18.4 1.2 0.0021 18.4 1.2 3.6 2 1 0 2 2 2 1 Domain of unknown function (DUF1772) DUF3341 PF11821.8 KUM61241.1 - 0.29 10.7 1.9 2.3 7.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) DUF1751 PF08551.10 KUM61241.1 - 1.2 9.7 7.2 46 4.7 0.1 3.6 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) Yos1 PF08571.10 KUM61242.1 - 8.5e-37 125.3 0.7 9.4e-37 125.1 0.7 1.0 1 0 0 1 1 1 1 Yos1-like UCH PF00443.29 KUM61243.1 - 2.3e-56 191.2 0.1 4.3e-56 190.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KUM61243.1 - 1.1e-28 100.8 0.3 7.3e-28 98.1 0.3 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KUM61243.1 - 0.0022 17.5 4.0 0.039 13.4 2.2 2.7 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase tRNA-synt_His PF13393.6 KUM61244.1 - 9.9e-37 126.9 0.0 8.8e-31 107.3 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KUM61244.1 - 6e-10 39.1 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KUM61244.1 - 3.1e-05 24.0 0.0 4.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 KUM61244.1 - 0.048 13.2 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs FAD_binding_3 PF01494.19 KUM61245.1 - 1.4e-21 77.1 0.0 9.1e-13 48.2 0.0 3.1 2 1 0 3 3 3 3 FAD binding domain SE PF08491.10 KUM61245.1 - 5.3e-06 25.7 0.0 8.5e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 KUM61245.1 - 0.0096 15.0 0.1 0.031 13.3 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KUM61245.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM61245.1 - 0.02 14.9 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Mlf1IP PF10248.9 KUM61245.1 - 0.062 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Trp_halogenase PF04820.14 KUM61245.1 - 0.094 11.5 0.1 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.6 KUM61245.1 - 0.096 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KUM61245.1 - 0.1 11.2 0.1 0.15 10.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 KUM61245.1 - 0.18 11.0 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family PX PF00787.24 KUM61246.1 - 1.3e-19 70.2 0.2 2.5e-19 69.3 0.2 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KUM61246.1 - 2.3e-15 56.8 5.8 1.7e-07 31.0 0.5 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Sec34 PF04136.15 KUM61246.1 - 0.0048 16.8 0.2 0.013 15.4 0.0 1.8 2 1 0 2 2 2 1 Sec34-like family FlaC_arch PF05377.11 KUM61246.1 - 0.088 13.2 1.0 16 6.0 0.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) BAR PF03114.18 KUM61246.1 - 0.19 11.3 5.7 0.84 9.2 2.3 2.4 2 1 0 2 2 2 0 BAR domain Syntaxin-6_N PF09177.11 KUM61246.1 - 0.45 11.1 4.0 8.3 7.0 0.1 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 KUM61246.1 - 0.47 10.5 2.2 11 6.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.13 KUM61246.1 - 0.85 10.4 4.7 1.9 9.2 0.0 3.0 3 0 0 3 3 3 0 Occludin homology domain Prefoldin_2 PF01920.20 KUM61246.1 - 1.3 9.1 3.9 3.8 7.5 0.2 2.4 2 0 0 2 2 2 0 Prefoldin subunit Peptidase_S8 PF00082.22 KUM61247.1 - 1.1e-37 129.9 0.2 2.3e-37 128.9 0.2 1.5 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KUM61247.1 - 1.8e-26 92.0 0.1 3.5e-26 91.0 0.1 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KUM61247.1 - 0.058 14.2 0.0 0.14 13.0 0.0 1.6 1 0 0 1 1 1 0 Peptidase S8 pro-domain Amino_oxidase PF01593.24 KUM61248.1 - 4.7e-83 280.0 0.0 9.8e-72 242.7 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 KUM61248.1 - 2.9e-13 50.0 0.1 9.2e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain NAD_binding_8 PF13450.6 KUM61248.1 - 3.5e-07 30.3 0.0 7.7e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 KUM61248.1 - 0.0002 21.7 0.8 0.00044 20.6 0.8 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box DAO PF01266.24 KUM61248.1 - 0.00085 19.0 0.1 0.0018 18.0 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM61248.1 - 0.011 15.0 0.1 0.082 12.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HMG_box_2 PF09011.10 KUM61248.1 - 0.1 13.2 0.8 0.22 12.1 0.8 1.6 1 0 0 1 1 1 0 HMG-box domain HI0933_like PF03486.14 KUM61248.1 - 0.13 10.9 0.0 1.1 7.9 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein HpcH_HpaI PF03328.14 KUM61249.1 - 5.7e-41 140.1 0.1 3.5e-40 137.5 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KUM61249.1 - 6.2e-12 45.3 0.0 3.7e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF1771 PF08590.10 KUM61250.1 - 6.1e-15 55.3 12.3 8.6e-15 54.9 10.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KUM61250.1 - 5.8e-10 39.4 0.1 3.3e-09 37.0 0.1 2.3 2 0 0 2 2 2 1 Smr domain zf_CCCH_4 PF18345.1 KUM61250.1 - 9.4e-08 31.9 9.4 2.1e-05 24.4 1.2 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KUM61250.1 - 2e-06 27.6 1.7 0.0045 16.9 0.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KUM61250.1 - 0.00016 21.9 2.3 0.22 11.8 0.0 2.4 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KUM61250.1 - 0.00025 20.7 12.4 0.0046 16.7 1.5 3.1 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KUM61250.1 - 0.00033 21.0 6.1 0.18 12.3 1.0 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger CUE PF02845.16 KUM61250.1 - 0.16 11.7 1.7 0.23 11.2 0.1 2.1 2 0 0 2 2 2 0 CUE domain Torus PF16131.5 KUM61250.1 - 0.9 10.3 3.5 4.1 8.1 0.6 2.5 1 1 1 2 2 2 0 Torus domain Aldedh PF00171.22 KUM61252.1 - 1e-136 456.1 0.5 1.2e-136 455.9 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family POM121 PF15229.6 KUM61252.1 - 0.011 15.4 3.5 0.011 15.4 3.5 1.5 2 0 0 2 2 2 0 POM121 family Calreticulin PF00262.18 KUM61253.1 - 1.1e-168 560.8 15.3 1.6e-168 560.3 15.3 1.2 1 0 0 1 1 1 1 Calreticulin family DUF1911 PF08929.10 KUM61253.1 - 0.09 13.6 0.0 0.2 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) p450 PF00067.22 KUM61254.1 - 2.6e-71 240.8 0.0 3.3e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FLYWCH_N PF15423.6 KUM61254.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein Vps5 PF09325.10 KUM61255.1 - 2.1e-88 295.9 4.5 2.1e-88 295.9 4.5 1.3 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 KUM61255.1 - 7e-24 84.0 0.2 1.4e-23 83.0 0.0 1.6 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 KUM61255.1 - 0.0069 16.1 6.5 0.4 10.3 1.8 2.3 1 1 1 2 2 2 2 BAR domain of APPL family DUF3450 PF11932.8 KUM61255.1 - 0.31 10.3 7.9 0.074 12.3 4.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Aldolase_II PF00596.21 KUM61256.1 - 2.4e-42 145.0 0.0 2.9e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3275 PF11679.8 KUM61257.1 - 0.0057 16.7 2.4 0.0057 16.7 2.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3275) IER PF05760.12 KUM61257.1 - 0.061 13.6 0.2 0.12 12.7 0.1 1.4 1 1 0 1 1 1 0 Immediate early response protein (IER) Flavin_Reduct PF01613.18 KUM61258.1 - 9e-28 97.3 0.0 1.4e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain DUF4505 PF14956.6 KUM61258.1 - 0.2 11.4 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) Nas2_N PF18265.1 KUM61259.1 - 0.11 12.5 3.3 0.18 11.8 0.9 2.4 2 0 0 2 2 2 0 Nas2 N_terminal domain NUDIX PF00293.28 KUM61260.1 - 2.4e-15 56.7 0.0 3.8e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain INCENP_ARK-bind PF03941.15 KUM61262.1 - 4.9e-16 58.4 2.1 1.9e-15 56.5 2.1 2.2 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region PTR2 PF00854.21 KUM61263.1 - 6.8e-58 196.4 2.2 1.1e-57 195.7 2.2 1.3 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 KUM61264.1 - 5.5e-26 91.3 36.4 3.4e-25 88.7 34.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM61264.1 - 0.0058 15.1 2.9 0.0081 14.6 2.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GPR_Gpa2_C PF11970.8 KUM61265.1 - 0.0022 18.0 0.1 0.81 9.8 0.0 2.1 2 0 0 2 2 2 2 G protein-coupled glucose receptor regulating Gpa2 C-term Hema_HEFG PF02710.14 KUM61265.1 - 0.12 12.6 0.0 10 6.3 0.0 2.1 2 0 0 2 2 2 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein Zn_clus PF00172.18 KUM61267.1 - 2.5e-08 33.9 12.1 3.9e-08 33.3 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM61267.1 - 0.0019 17.1 0.0 0.0048 15.8 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain PIF1 PF05970.14 KUM61269.1 - 3.9e-11 42.7 0.0 4.9e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KUM61269.1 - 1.3e-09 38.0 0.0 1.7e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KUM61269.1 - 1.4e-07 31.9 0.2 2.6e-07 31.1 0.2 1.4 1 1 0 1 1 1 1 AAA domain Torsin PF06309.11 KUM61269.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.4 1 1 0 1 1 1 0 Torsin NB-ARC PF00931.22 KUM61269.1 - 0.013 14.7 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 KUM61269.1 - 0.025 14.6 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KUM61269.1 - 0.041 14.2 0.1 0.089 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.7 KUM61269.1 - 0.048 12.6 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.6 KUM61269.1 - 0.051 13.3 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 KUM61269.1 - 0.056 13.2 0.0 0.2 11.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 KUM61269.1 - 0.059 13.3 0.1 5.7 6.8 0.1 2.1 2 0 0 2 2 2 0 NTPase AAA PF00004.29 KUM61269.1 - 0.11 12.9 0.1 0.2 12.1 0.1 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KUM61269.1 - 0.13 11.8 1.0 0.5 9.8 1.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 KUM61269.1 - 0.15 10.9 0.4 0.39 9.6 0.1 1.7 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 KUM61269.1 - 0.21 12.0 0.2 0.54 10.6 0.1 1.6 1 1 1 2 2 2 0 AAA ATPase domain RHS_repeat PF05593.14 KUM61270.1 - 4.3e-16 59.0 67.8 2e-05 25.0 0.0 18.2 15 4 1 18 18 18 8 RHS Repeat Reticulon PF02453.17 KUM61272.1 - 4.5e-27 94.9 3.4 6.1e-27 94.5 3.4 1.2 1 0 0 1 1 1 1 Reticulon BRX_N PF13713.6 KUM61272.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain RabGAP-TBC PF00566.18 KUM61273.1 - 4.1e-49 167.2 0.0 1.5e-48 165.3 0.0 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain YabA PF06156.13 KUM61273.1 - 0.54 10.9 0.1 0.54 10.9 0.1 3.2 3 0 0 3 3 3 0 Initiation control protein YabA DUF3450 PF11932.8 KUM61273.1 - 7.7 5.7 20.1 0.24 10.6 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) PIN_8 PF18476.1 KUM61273.1 - 9.5 6.0 17.0 0.69 9.7 7.6 2.8 2 1 1 3 3 3 0 PIN like domain DNA_topoisoIV PF00521.20 KUM61274.1 - 3e-136 454.7 0.0 5e-136 454.0 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KUM61274.1 - 4.7e-52 175.6 2.8 5.4e-51 172.2 2.5 2.7 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KUM61274.1 - 2.4e-24 85.8 0.2 6.1e-24 84.4 0.2 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KUM61274.1 - 1.9e-15 57.4 0.1 5.7e-15 55.8 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KUM61274.1 - 1.7e-06 28.1 0.0 7e-06 26.2 0.0 2.1 1 0 0 1 1 1 1 Toprim domain PspA_IM30 PF04012.12 KUM61277.1 - 0.00048 19.8 3.2 0.00049 19.7 3.2 1.0 1 0 0 1 1 1 1 PspA/IM30 family DUF3405 PF11885.8 KUM61278.1 - 6.4e-127 424.3 3.7 7.1e-127 424.1 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Glyco_hydro_92 PF07971.12 KUM61279.1 - 9.9e-148 492.9 0.3 1.2e-147 492.6 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KUM61279.1 - 1.4e-68 231.3 0.6 2.5e-68 230.5 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain adh_short_C2 PF13561.6 KUM61280.1 - 3.9e-56 190.2 5.2 4.6e-56 190.0 5.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM61280.1 - 2.8e-44 150.9 5.8 3.7e-44 150.5 5.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM61280.1 - 9.3e-11 42.0 3.6 1.6e-10 41.2 3.6 1.4 1 0 0 1 1 1 1 KR domain Pyr_redox_2 PF07992.14 KUM61280.1 - 0.0041 16.4 0.5 0.0066 15.7 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase YAcAr PF10686.9 KUM61280.1 - 0.027 14.4 0.6 0.21 11.6 0.4 2.3 1 1 1 2 2 2 0 YspA, cpYpsA-related SLOG family NAD_Gly3P_dh_N PF01210.23 KUM61280.1 - 0.059 13.3 1.6 0.082 12.9 0.4 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Mur_ligase PF01225.25 KUM61280.1 - 0.061 13.7 0.7 0.2 12.0 0.5 1.9 2 0 0 2 2 2 0 Mur ligase family, catalytic domain ACT PF01842.25 KUM61280.1 - 0.067 13.0 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 ACT domain ATP-synt_F PF01990.17 KUM61280.1 - 0.14 12.4 0.6 26 5.2 0.0 3.0 2 1 0 2 2 2 0 ATP synthase (F/14-kDa) subunit FAD_binding_3 PF01494.19 KUM61281.1 - 1e-73 248.6 0.0 1.3e-73 248.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KUM61281.1 - 2.1e-25 89.7 0.0 4.7e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KUM61281.1 - 4.2e-07 29.5 0.0 0.0033 16.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM61281.1 - 8.2e-06 25.6 0.1 0.0014 18.2 0.0 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KUM61281.1 - 0.00023 21.7 0.0 0.003 18.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KUM61281.1 - 0.00061 18.6 0.1 0.00094 18.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KUM61281.1 - 0.00079 19.6 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KUM61281.1 - 0.0051 15.9 0.1 0.0081 15.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KUM61281.1 - 0.007 15.7 0.1 1.6 8.1 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KUM61281.1 - 0.019 14.3 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KUM61281.1 - 0.021 14.1 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KUM61281.1 - 0.044 13.0 0.1 0.094 11.9 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KUM61281.1 - 0.06 12.2 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.24 KUM61281.1 - 0.078 12.1 0.1 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KUM61281.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 KUM61281.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CMAS PF02353.20 KUM61282.1 - 3e-58 197.3 0.3 3.7e-58 197.0 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KUM61282.1 - 6.8e-09 35.8 0.0 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM61282.1 - 7.3e-09 36.2 0.0 1.5e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM61282.1 - 1.3e-07 32.2 0.0 2.9e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM61282.1 - 0.0016 19.1 0.0 0.0029 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KUM61282.1 - 0.0077 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 KUM61282.1 - 0.017 14.7 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 KUM61282.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KUM61282.1 - 0.061 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KUM61282.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Lactamase_B PF00753.27 KUM61283.1 - 7.6e-05 22.8 0.0 0.00013 22.0 0.0 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KUM61283.1 - 0.024 14.1 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain FAD_binding_3 PF01494.19 KUM61284.1 - 1.9e-13 50.4 0.0 7.6e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KUM61284.1 - 4.9e-07 29.7 4.5 0.021 14.4 3.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM61284.1 - 5.3e-07 29.2 0.3 0.0015 17.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KUM61284.1 - 1.1e-06 27.6 0.2 2.6e-06 26.4 0.2 1.6 1 1 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 KUM61284.1 - 2.3e-06 26.7 3.4 0.011 14.7 0.1 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 KUM61284.1 - 7.1e-05 22.1 5.5 0.00047 19.3 4.9 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KUM61284.1 - 9.2e-05 22.9 0.7 0.071 13.7 0.7 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KUM61284.1 - 0.00015 21.0 1.4 0.00062 18.9 1.4 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KUM61284.1 - 0.0012 19.0 0.9 0.0045 17.2 0.9 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KUM61284.1 - 0.0021 18.0 1.2 0.0037 17.2 1.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KUM61284.1 - 0.018 14.3 0.7 0.077 12.2 0.7 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KUM61284.1 - 0.024 14.0 2.8 0.044 13.1 2.3 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KUM61284.1 - 0.034 13.4 0.4 0.069 12.4 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KUM61284.1 - 0.061 12.4 3.2 0.1 11.7 3.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Rossmann-like PF10727.9 KUM61284.1 - 0.064 13.1 0.4 0.17 11.8 0.4 1.6 1 0 0 1 1 1 0 Rossmann-like domain SE PF08491.10 KUM61284.1 - 0.22 10.5 0.0 0.46 9.5 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase Chlorosome_CsmC PF11098.8 KUM61286.1 - 0.089 12.8 4.2 0.11 12.5 4.2 1.2 1 0 0 1 1 1 0 Chlorosome envelope protein C MFS_1 PF07690.16 KUM61287.1 - 3.3e-25 88.8 45.9 6.7e-24 84.5 26.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM61287.1 - 1.2e-16 60.7 16.3 2.1e-16 59.9 16.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter Bul1_C PF04426.12 KUM61288.1 - 0.0035 16.8 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus Bul1_N PF04425.12 KUM61288.1 - 0.041 12.6 0.4 0.063 12.0 0.4 1.2 1 0 0 1 1 1 0 Bul1 N terminus Matrix PF00661.21 KUM61288.1 - 0.19 10.4 0.0 0.3 9.7 0.0 1.2 1 0 0 1 1 1 0 Viral matrix protein DUF2207 PF09972.9 KUM61289.1 - 0.027 13.3 0.0 0.027 13.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LAX PF15681.5 KUM61289.1 - 0.045 12.6 0.6 0.068 12.0 0.6 1.3 1 0 0 1 1 1 0 Lymphocyte activation family X Mid2 PF04478.12 KUM61289.1 - 0.065 13.1 0.0 0.074 12.9 0.0 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Orf78 PF06024.12 KUM61289.1 - 0.17 12.2 0.0 0.21 11.9 0.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) Amidase PF01425.21 KUM61290.1 - 1.9e-81 274.4 0.0 1.6e-79 268.0 0.0 2.1 1 1 0 1 1 1 1 Amidase Pkinase PF00069.25 KUM61292.1 - 1e-15 57.8 0.0 1.3e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM61292.1 - 0.0026 17.1 0.1 0.0053 16.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Ring_hydroxyl_A PF00848.19 KUM61295.1 - 1.6e-20 74.0 6.2 5.3e-10 39.6 3.1 2.3 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KUM61295.1 - 2.8e-14 52.8 0.0 5.9e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain adh_short_C2 PF13561.6 KUM61297.1 - 6.5e-58 196.0 0.1 7.7e-58 195.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM61297.1 - 9.9e-43 145.9 0.0 1.3e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM61297.1 - 6e-10 39.3 0.0 9.2e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 KR domain COesterase PF00135.28 KUM61298.1 - 4e-93 313.0 0.0 6.5e-93 312.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KUM61298.1 - 1.4e-09 38.2 0.5 5.4e-09 36.2 0.5 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KUM61298.1 - 0.00021 20.9 0.2 0.00036 20.1 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family EamA PF00892.20 KUM61299.1 - 6.2 7.0 10.7 2.7 8.1 0.1 3.1 3 0 0 3 3 3 0 EamA-like transporter family DLH PF01738.18 KUM61300.1 - 1.9e-13 50.5 0.0 2.2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family MFS_1 PF07690.16 KUM61301.1 - 6.8e-39 133.8 44.3 6.8e-39 133.8 44.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM61301.1 - 6.2e-12 45.1 18.4 6.2e-12 45.1 18.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Fungal_trans PF04082.18 KUM61303.1 - 3.7e-16 58.9 1.1 4.8e-16 58.6 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain PSDC PF12588.8 KUM61304.1 - 7.5e-59 197.7 0.0 1.1e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KUM61304.1 - 3.5e-38 131.2 0.0 5.9e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 KUM61304.1 - 0.2 11.5 0.2 28 4.6 0.0 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like MFS_1 PF07690.16 KUM61305.1 - 1e-30 106.9 29.4 1e-30 106.9 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3522 PF12036.8 KUM61305.1 - 0.16 12.2 0.2 0.16 12.2 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3522) Ribosomal_L7Ae PF01248.26 KUM61306.1 - 4.2e-26 90.5 0.0 5.1e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KUM61306.1 - 0.00013 22.1 0.0 0.00013 22.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KUM61306.1 - 0.005 16.7 0.0 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain DUF1962 PF09227.10 KUM61307.1 - 4.2e-31 107.1 15.2 5.1e-31 106.8 15.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1962) Form_Nir_trans PF01226.17 KUM61308.1 - 0.011 15.1 1.4 0.02 14.3 1.4 1.6 1 0 0 1 1 1 0 Formate/nitrite transporter Glyco_transf_8 PF01501.20 KUM61309.1 - 1.1e-17 64.4 0.0 1.4e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 CCDC73 PF15818.5 KUM61309.1 - 0.0026 15.7 0.0 0.0035 15.3 0.0 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 73 family Mannosyl_trans3 PF11051.8 KUM61309.1 - 0.22 10.8 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative XPG_N PF00752.17 KUM61310.1 - 2.8e-05 24.5 0.0 6e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KUM61311.1 - 7.4e-30 103.2 2.5 8.3e-30 103.0 0.0 2.3 3 0 0 3 3 3 1 XPG I-region XPG_N PF00752.17 KUM61311.1 - 5.7e-16 58.8 0.2 3e-15 56.5 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KUM61311.1 - 0.00035 21.1 0.2 0.0028 18.2 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold SET PF00856.28 KUM61311.1 - 0.44 10.9 2.1 0.73 10.2 1.1 1.7 1 1 0 2 2 2 0 SET domain HXXSHH PF07586.11 KUM61311.1 - 6.9 6.1 8.0 1.7 8.1 4.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) Acyl-CoA_dh_N PF02771.16 KUM61312.1 - 1.1e-28 100.1 0.2 2.3e-28 99.1 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KUM61312.1 - 1.9e-25 89.8 1.4 4.1e-25 88.7 1.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KUM61312.1 - 1.1e-16 60.8 0.0 2.1e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KUM61312.1 - 5.9e-08 33.1 1.8 5.9e-08 33.1 1.8 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Zn_clus PF00172.18 KUM61313.1 - 1.9e-08 34.3 8.4 3e-08 33.6 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM61313.1 - 0.00072 18.7 0.1 0.0016 17.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase PF00903.25 KUM61314.1 - 0.0026 17.9 0.0 0.007 16.5 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3552 PF12072.8 KUM61314.1 - 0.057 12.8 3.2 0.11 11.8 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Gly-zipper_Omp PF13488.6 KUM61314.1 - 0.058 13.4 5.1 0.11 12.5 5.1 1.4 1 0 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.15 KUM61314.1 - 0.089 12.7 5.1 0.22 11.4 5.1 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain UQ_con PF00179.26 KUM61315.1 - 3.5e-52 175.8 0.0 4.2e-52 175.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KUM61315.1 - 0.0071 16.0 0.0 0.0084 15.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KUM61315.1 - 0.05 13.9 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KUM61315.1 - 0.069 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acetyltransf_13 PF13880.6 KUM61316.1 - 6.9e-29 99.6 0.0 1.6e-28 98.5 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KUM61316.1 - 1.4e-14 53.6 0.3 2.5e-14 52.8 0.3 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO DAO_C PF16901.5 KUM61316.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase EMG1 PF03587.14 KUM61317.1 - 8.2e-80 267.1 0.1 1e-79 266.8 0.1 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DP-EP PF08985.11 KUM61319.1 - 0.13 12.4 0.1 0.21 11.8 0.1 1.3 1 0 0 1 1 1 0 DP-EP family TolA_bind_tri PF16331.5 KUM61319.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation HUN PF08729.10 KUM61320.1 - 7.4e-08 32.3 0.1 1.6e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain RPAP1_C PF08620.10 KUM61321.1 - 1.6e-24 85.8 0.0 2.8e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KUM61321.1 - 1.4e-18 66.4 9.6 5.8e-18 64.4 9.3 2.1 2 0 0 2 2 2 1 RPAP1-like, N-terminal Pkinase PF00069.25 KUM61322.1 - 2.5e-64 217.2 0.0 3.1e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM61322.1 - 1.9e-35 122.4 0.0 2.6e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KUM61322.1 - 6.5e-06 25.2 0.0 1.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KUM61322.1 - 7.5e-05 22.2 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KUM61322.1 - 0.032 13.3 0.0 0.047 12.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KUM61322.1 - 0.057 12.3 0.0 0.14 11.1 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KUM61322.1 - 0.059 13.3 0.0 0.19 11.6 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KUM61322.1 - 0.089 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family eIF2A PF08662.11 KUM61323.1 - 1.4e-81 273.0 0.0 1.1e-80 270.1 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KUM61323.1 - 0.0012 19.7 0.7 0.19 12.7 0.1 3.9 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC1 PF12859.7 KUM61325.1 - 2.3e-31 109.0 0.4 2.3e-31 109.0 0.4 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KUM61325.1 - 6.7e-05 23.1 4.0 0.81 10.2 0.0 4.2 4 0 0 4 4 4 3 Proteasome/cyclosome repeat TFIID_20kDa PF03847.13 KUM61327.1 - 7.2e-21 74.5 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 KUM61327.1 - 0.0044 17.4 0.0 0.0044 17.4 0.0 3.1 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KUM61327.1 - 0.065 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PIP5K PF01504.18 KUM61328.1 - 2e-102 342.1 0.5 3.9e-102 341.1 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Linker_histone PF00538.19 KUM61331.1 - 7.2e-31 106.4 0.3 1.7e-30 105.2 0.3 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family Oxysterol_BP PF01237.18 KUM61333.1 - 1.1e-119 399.7 0.3 9.3e-119 396.6 0.0 2.6 3 1 0 3 3 3 1 Oxysterol-binding protein PH_8 PF15409.6 KUM61333.1 - 7.2e-38 128.8 0.1 1.4e-37 127.8 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KUM61333.1 - 3.6e-07 30.6 0.4 2.1e-06 28.2 0.1 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KUM61333.1 - 0.031 14.7 2.6 1.9 9.0 0.1 3.1 2 1 1 3 3 3 0 Pleckstrin homology domain GOLD_2 PF13897.6 KUM61333.1 - 0.21 12.1 0.0 0.21 12.1 0.0 2.3 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking SH2_2 PF14633.6 KUM61334.1 - 3.8e-86 288.0 0.0 8.3e-86 286.9 0.0 1.6 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 KUM61334.1 - 9.4e-36 122.7 1.2 2.5e-35 121.4 1.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 KUM61334.1 - 2e-31 108.4 0.0 3.9e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KUM61334.1 - 1e-27 96.8 0.0 2.7e-27 95.4 0.0 1.8 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 KUM61334.1 - 1.6e-16 60.6 18.4 1.6e-16 60.6 18.4 5.5 5 2 1 6 6 6 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 KUM61334.1 - 5.2e-08 33.7 2.7 1.5e-06 29.0 2.7 3.4 1 1 0 1 1 1 1 HHH domain SH2 PF00017.24 KUM61334.1 - 0.00011 22.2 0.0 0.00028 20.9 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Tex_N PF09371.10 KUM61334.1 - 0.0017 18.1 8.8 0.018 14.7 0.0 4.3 4 0 0 4 4 4 1 Tex-like protein N-terminal domain HHH_3 PF12836.7 KUM61334.1 - 0.0017 18.5 0.0 0.0046 17.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif B12-binding PF02310.19 KUM61334.1 - 0.038 14.0 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 B12 binding domain NAD_binding_1 PF00175.21 KUM61335.1 - 5.8e-13 49.5 0.0 1e-12 48.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KUM61335.1 - 9.8e-09 35.8 0.0 2.9e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.12 KUM61335.1 - 2.3e-05 24.5 0.0 0.00021 21.5 0.0 2.4 2 1 1 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 KUM61335.1 - 3.7e-05 24.0 0.0 7.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Guanylate_kin PF00625.21 KUM61335.1 - 0.00024 20.8 0.1 0.00067 19.4 0.0 1.8 1 1 1 2 2 2 1 Guanylate kinase Protoglobin PF11563.8 KUM61335.1 - 0.018 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Protoglobin DUF4754 PF15946.5 KUM61335.1 - 0.1 12.9 0.2 0.38 11.0 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4754) MIP PF00230.20 KUM61336.1 - 1.9e-45 155.3 7.9 2.4e-45 155.0 7.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF3533 PF12051.8 KUM61338.1 - 2e-127 425.3 8.1 2.3e-127 425.1 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF202 PF02656.15 KUM61338.1 - 0.18 12.2 0.1 0.18 12.2 0.1 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF202) Sugar_tr PF00083.24 KUM61339.1 - 2.4e-37 128.9 19.8 2.5e-36 125.5 19.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM61339.1 - 1.9e-25 89.6 24.8 1.9e-25 89.6 24.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 KUM61340.1 - 0.0052 17.0 0.0 0.0093 16.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KUM61340.1 - 0.13 12.2 0.0 0.8 9.7 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.15 KUM61341.1 - 3.1e-05 23.9 0.1 5.5e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KUM61341.1 - 0.12 13.1 0.4 0.16 12.8 0.4 1.4 1 1 0 1 1 1 0 Complex1_LYR-like RAC_head PF16717.5 KUM61342.1 - 9.5e-31 106.7 0.9 9.5e-31 106.7 0.9 3.2 2 1 2 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 KUM61342.1 - 3e-16 59.3 0.4 3e-16 59.3 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain CemA PF03040.14 KUM61342.1 - 2.3 8.1 4.5 3.6 7.5 4.5 1.3 1 0 0 1 1 1 0 CemA family ECH_1 PF00378.20 KUM61343.1 - 1.9e-41 142.0 0.0 2.4e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KUM61343.1 - 1.6e-27 96.9 0.0 1e-25 91.0 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase PQ-loop PF04193.14 KUM61344.1 - 0.00037 20.2 2.8 0.00042 20.0 0.1 2.5 1 1 0 2 2 2 1 PQ loop repeat BCLP PF12304.8 KUM61344.1 - 1.2 8.6 4.8 4.5 6.8 4.8 1.9 1 1 0 1 1 1 0 Beta-casein like protein Sterol_MT_C PF08498.10 KUM61345.1 - 4.6e-27 94.1 0.1 1.1e-26 93.0 0.1 1.6 2 0 0 2 2 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KUM61345.1 - 2.3e-21 76.2 0.0 4.4e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM61345.1 - 2e-19 70.1 0.0 3.9e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM61345.1 - 2.5e-17 63.1 0.0 3.8e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM61345.1 - 2.5e-11 43.7 0.0 3.9e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KUM61345.1 - 1.2e-10 41.2 0.1 1.7e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KUM61345.1 - 7.7e-10 38.5 0.0 1.3e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KUM61345.1 - 5.9e-09 36.6 0.0 1.2e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KUM61345.1 - 0.00029 19.5 0.0 0.00038 19.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_15 PF09445.10 KUM61345.1 - 0.00044 19.9 0.0 0.00075 19.1 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KUM61345.1 - 0.00099 18.6 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KUM61345.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KUM61345.1 - 0.0071 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 KUM61345.1 - 0.0072 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 KUM61345.1 - 0.0089 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KUM61345.1 - 0.044 13.8 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 KUM61345.1 - 0.049 12.9 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain TehB PF03848.14 KUM61345.1 - 0.074 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB RRM_1 PF00076.22 KUM61346.1 - 2.2e-08 33.8 0.0 3.7e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KUM61346.1 - 0.0046 16.9 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Pectate_lyase_3 PF12708.7 KUM61347.1 - 2.5e-55 187.6 17.6 1.2e-46 159.3 4.3 3.2 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KUM61347.1 - 0.018 14.7 1.5 0.027 14.2 0.0 2.1 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase SBBP PF06739.11 KUM61347.1 - 0.038 14.0 0.0 0.14 12.2 0.0 2.0 1 0 0 1 1 1 0 Beta-propeller repeat APA3_viroporin PF11289.8 KUM61347.1 - 0.11 12.0 0.1 0.29 10.7 0.1 1.6 1 0 0 1 1 1 0 Coronavirus accessory protein 3a AA_permease_2 PF13520.6 KUM61349.1 - 3.7e-72 243.5 42.7 4.4e-72 243.2 42.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM61349.1 - 8.7e-12 44.4 35.9 1.2e-11 43.9 35.9 1.2 1 0 0 1 1 1 1 Amino acid permease Arc PF03869.14 KUM61350.1 - 0.0084 15.9 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 Arc-like DNA binding domain DUF883 PF05957.13 KUM61350.1 - 0.061 13.9 2.2 4.9 7.8 1.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Alpha_GJ PF03229.13 KUM61351.1 - 0.0096 16.5 17.4 0.27 11.8 8.1 2.2 2 0 0 2 2 2 2 Alphavirus glycoprotein J LIF_OSM PF01291.17 KUM61351.1 - 0.049 13.8 0.5 0.065 13.4 0.5 1.2 1 0 0 1 1 1 0 LIF / OSM family Sugar_tr PF00083.24 KUM61352.1 - 1.6e-105 353.6 20.8 2.1e-105 353.2 20.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM61352.1 - 1.5e-28 99.7 34.8 2.3e-19 69.5 9.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 KUM61352.1 - 0.028 12.7 5.6 0.99 7.5 0.4 2.5 3 0 0 3 3 3 0 BT1 family PAP2_3 PF14378.6 KUM61352.1 - 1.6 8.4 8.8 0.16 11.6 1.0 3.0 4 0 0 4 4 4 0 PAP2 superfamily HLH PF00010.26 KUM61353.1 - 9.7e-10 38.3 0.0 1.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 KUM61353.1 - 0.033 14.4 0.9 0.063 13.5 0.9 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper CAV_VP3 PF04771.12 KUM61353.1 - 0.29 11.3 6.3 0.56 10.4 6.3 1.4 1 0 0 1 1 1 0 Chicken anaemia virus VP-3 protein Peptidase_S64 PF08192.11 KUM61353.1 - 7.7 4.9 10.6 10 4.5 10.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 AA_permease_2 PF13520.6 KUM61354.1 - 1.7e-59 201.8 48.6 2.1e-59 201.4 48.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM61354.1 - 6.7e-22 77.7 38.1 8.7e-22 77.3 38.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.8 KUM61354.1 - 0.3 11.3 2.5 0.47 10.7 0.2 2.6 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 DUF1182 PF06681.13 KUM61354.1 - 4.1 6.9 13.0 0.087 12.4 2.2 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1182) Pro-kuma_activ PF09286.11 KUM61355.1 - 3.2e-36 124.7 0.1 9.2e-36 123.3 0.1 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KUM61355.1 - 2.2e-11 43.6 0.0 5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Subtilase family adh_short PF00106.25 KUM61356.1 - 4.3e-14 52.4 0.0 2.6e-10 40.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM61356.1 - 9.1e-05 22.1 0.0 0.0025 17.4 0.0 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM61356.1 - 0.025 14.5 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 KR domain NmrA PF05368.13 KUM61357.1 - 1.4e-21 77.2 0.0 1.7e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM61357.1 - 4.9e-16 59.2 0.0 7.6e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KUM61357.1 - 0.00022 20.3 0.0 0.00031 19.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family APH PF01636.23 KUM61360.1 - 2e-07 31.2 0.0 2.7e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KUM61360.1 - 0.014 14.7 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 KUM61360.1 - 0.038 12.9 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ank_2 PF12796.7 KUM61361.1 - 1.2e-43 147.5 0.1 2.9e-12 47.0 0.0 6.4 4 3 3 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 KUM61361.1 - 4.8e-31 105.8 8.1 6.8e-06 26.3 0.0 9.9 8 2 1 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 KUM61361.1 - 6.1e-31 106.4 10.4 7.7e-06 26.4 0.0 10.1 6 4 3 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM61361.1 - 5.8e-28 93.8 6.8 0.00051 20.3 0.0 11.5 13 0 0 13 13 13 7 Ankyrin repeat Ank_5 PF13857.6 KUM61361.1 - 1.7e-26 91.9 11.3 2.3e-07 31.0 0.0 10.1 9 1 3 12 12 12 4 Ankyrin repeats (many copies) Phosphoesterase PF04185.14 KUM61362.1 - 7.9e-34 117.4 0.5 2.2e-33 116.0 0.5 1.7 1 1 0 1 1 1 1 Phosphoesterase family HIF-1a_CTAD PF08778.10 KUM61362.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain Methyltransf_2 PF00891.18 KUM61364.1 - 1.3e-16 60.5 0.0 2.5e-16 59.6 0.0 1.4 2 0 0 2 2 2 1 O-methyltransferase domain p450 PF00067.22 KUM61365.1 - 8.4e-15 54.5 0.0 1.1e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LRR_4 PF12799.7 KUM61366.1 - 5.9e-33 112.4 30.2 2.1e-08 34.3 0.6 7.2 2 2 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KUM61366.1 - 6.5e-19 67.4 31.9 2.9e-06 27.0 0.7 6.3 4 1 2 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 KUM61366.1 - 4.7e-16 58.8 13.8 4.6e-08 32.8 1.9 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KUM61366.1 - 1.7e-07 30.7 12.8 0.18 11.9 0.3 6.9 6 1 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 KUM61366.1 - 8.1e-05 22.6 21.8 10 7.2 0.2 8.7 8 2 1 9 9 9 2 Leucine Rich Repeat NIF PF03031.18 KUM61367.1 - 3.8e-54 182.7 0.1 5.3e-54 182.2 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ABC_membrane_2 PF06472.15 KUM61368.1 - 6.3e-87 291.4 0.1 1.8e-86 289.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KUM61368.1 - 2.8e-11 44.1 0.0 5.6e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter THOC7 PF05615.13 KUM61368.1 - 0.014 15.7 0.5 0.025 14.8 0.5 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 AAA_23 PF13476.6 KUM61368.1 - 0.017 15.6 2.3 2.3 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KUM61368.1 - 0.11 12.3 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain RuvB_N PF05496.12 KUM61368.1 - 0.15 11.8 0.0 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Clr2 PF10383.9 KUM61369.1 - 6.7e-33 114.5 0.0 2.7e-32 112.6 0.0 1.9 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 Gpr1_Fun34_YaaH PF01184.19 KUM61370.1 - 3e-85 285.0 15.9 3.5e-85 284.8 15.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family 2OG-FeII_Oxy PF03171.20 KUM61371.1 - 0.014 15.8 0.0 0.05 14.1 0.0 2.0 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KUM61371.1 - 0.02 15.7 0.0 0.034 14.9 0.0 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Peptidase_M24 PF00557.24 KUM61372.1 - 2.2e-43 148.4 0.0 2.7e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KUM61372.1 - 2.8e-20 72.3 7.6 5.5e-20 71.4 7.6 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KUM61372.1 - 0.0033 17.5 5.6 0.0083 16.2 5.6 1.7 1 0 0 1 1 1 1 MYND finger Acyl_transf_2 PF02273.15 KUM61372.1 - 0.18 11.0 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase Peptidase_M24 PF00557.24 KUM61373.1 - 1.4e-34 119.7 0.1 1.8e-34 119.3 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF2439 PF10382.9 KUM61374.1 - 0.00028 21.1 0.0 0.00045 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) MFS_1 PF07690.16 KUM61375.1 - 5.3e-24 84.8 16.9 5.3e-24 84.8 16.9 2.2 3 0 0 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM61375.1 - 2.3e-05 23.5 1.1 2.3e-05 23.5 1.1 2.1 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KUM61375.1 - 0.00017 21.0 13.9 0.016 14.6 1.7 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB GTA_holin_3TM PF11351.8 KUM61375.1 - 0.43 11.1 3.1 7 7.2 0.0 3.2 2 1 0 2 2 2 0 Holin of 3TMs, for gene-transfer release zf_C2HC_14 PF18574.1 KUM61376.1 - 0.033 14.0 0.7 5.2 7.0 0.1 2.3 2 0 0 2 2 2 0 C2HC Zing finger domain Cupin_2 PF07883.11 KUM61377.1 - 5.7e-07 29.2 0.0 7.2e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KUM61377.1 - 0.011 15.3 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 0 Cupin DUF4437 PF14499.6 KUM61377.1 - 0.077 12.1 0.0 0.09 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) MFS_1 PF07690.16 KUM61378.1 - 1.2e-22 80.4 24.5 3e-22 79.0 24.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1147 PF06615.11 KUM61379.1 - 0.1 12.7 1.5 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1147) Amidase PF01425.21 KUM61380.1 - 5.3e-98 328.9 0.0 9.5e-98 328.1 0.0 1.4 1 1 0 1 1 1 1 Amidase Cas_NE0113 PF09623.10 KUM61380.1 - 0.046 13.4 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) SnoaL_2 PF12680.7 KUM61382.1 - 0.00025 21.6 0.0 0.00032 21.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KUM61382.1 - 0.015 15.7 0.0 0.02 15.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 KUM61382.1 - 0.03 14.4 0.0 0.038 14.1 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_3 PF13474.6 KUM61382.1 - 0.076 13.3 0.0 0.093 13.0 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Viral_cys_rich PF08008.12 KUM61384.1 - 0.05 13.6 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 Viral cysteine rich Aa_trans PF01490.18 KUM61385.1 - 6.2e-52 176.7 33.2 7.2e-52 176.5 33.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-Tim10_DDP PF02953.15 KUM61389.1 - 2.6e-23 81.4 0.7 3.1e-23 81.2 0.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger tRNA-synt_2 PF00152.20 KUM61390.1 - 1.8e-22 79.9 0.0 2.6e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KUM61390.1 - 3.3e-12 46.2 0.0 6.6e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 KUM61390.1 - 0.00015 21.9 0.0 0.012 15.8 0.0 2.1 1 1 1 2 2 2 2 OB-fold nucleic acid binding domain PEP_mutase PF13714.6 KUM61390.1 - 0.12 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase tRNA-synt_2 PF00152.20 KUM61391.1 - 1e-24 87.2 0.0 1.2e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) SICA_C PF12879.7 KUM61392.1 - 1.3e-05 25.3 3.2 0.23 11.5 3.2 2.9 1 1 0 1 1 1 1 SICA C-terminal inner membrane domain AAA PF00004.29 KUM61394.1 - 1.9e-19 70.4 0.1 1.2e-17 64.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KUM61394.1 - 0.00073 20.0 0.5 0.076 13.4 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KUM61394.1 - 0.0043 17.3 2.4 5.6 7.3 0.0 3.4 2 1 1 3 3 3 2 AAA domain AAA_17 PF13207.6 KUM61394.1 - 0.0077 16.7 0.0 0.087 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KUM61394.1 - 0.025 15.1 0.0 0.085 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KUM61394.1 - 0.062 13.3 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KUM61394.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 KUM61394.1 - 0.12 12.0 0.0 5.7 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF3461 PF11944.8 KUM61394.1 - 0.31 11.2 1.6 13 5.9 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3461) DASH_Dad1 PF08649.10 KUM61394.1 - 0.37 11.0 1.3 6.9 6.9 0.1 3.4 3 0 0 3 3 3 0 DASH complex subunit Dad1 Myb_DNA-binding PF00249.31 KUM61395.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain HSDR_N_2 PF13588.6 KUM61397.1 - 0.005 16.8 0.1 0.24 11.4 0.0 2.4 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) Pkinase PF00069.25 KUM61397.1 - 0.068 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain TrmO_C PF18389.1 KUM61397.1 - 0.072 13.2 0.1 0.24 11.5 0.1 1.9 1 0 0 1 1 1 0 TrmO C-terminal domain CENP-R PF06729.12 KUM61398.1 - 0.028 14.3 0.2 0.028 14.3 0.2 2.2 2 0 0 2 2 2 0 Kinetochore component, CENP-R DUF3136 PF11334.8 KUM61398.1 - 0.11 12.3 0.1 7.1 6.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) APH PF01636.23 KUM61399.1 - 0.00013 22.0 0.0 0.00035 20.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Med31 PF05669.12 KUM61400.1 - 0.06 13.4 1.7 4.4 7.4 0.1 3.0 3 1 0 3 3 3 0 SOH1 Pkinase_Tyr PF07714.17 KUM61403.1 - 6e-08 32.3 0.1 8.3e-08 31.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KUM61403.1 - 1.5e-07 31.1 0.0 2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF3723 PF12520.8 KUM61404.1 - 3.7e-96 322.8 0.2 6.1e-96 322.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) NARP1 PF12569.8 KUM61404.1 - 3.9 6.3 7.5 11 4.8 0.0 2.3 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Ank_2 PF12796.7 KUM61406.1 - 2e-41 140.4 22.5 1.2e-15 57.9 2.9 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM61406.1 - 1e-24 86.5 2.7 4.9e-06 27.0 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KUM61406.1 - 5.7e-19 67.6 15.1 0.0013 19.0 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KUM61406.1 - 3.7e-18 65.4 7.3 0.0024 18.1 0.2 4.8 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM61406.1 - 3.5e-11 42.3 4.6 0.81 10.5 0.1 4.6 5 0 0 5 5 5 4 Ankyrin repeat Stanniocalcin PF03298.13 KUM61406.1 - 0.00036 19.9 0.0 23 4.2 0.0 3.9 1 1 3 4 4 4 0 Stanniocalcin family HopJ PF08888.11 KUM61406.1 - 0.0021 18.3 1.0 8.9 6.6 0.0 4.0 1 1 3 4 4 4 2 HopJ type III effector protein SNAP PF14938.6 KUM61406.1 - 0.0066 15.9 1.4 0.12 11.8 0.1 1.9 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP DUF3710 PF12502.8 KUM61406.1 - 0.0086 15.8 0.8 12 5.6 0.1 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3710) DUF1409 PF07197.12 KUM61406.1 - 0.0098 15.8 0.1 28 4.7 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1409) YajC PF02699.15 KUM61406.1 - 0.011 15.6 2.4 8.5 6.3 0.2 3.8 1 1 3 4 4 4 0 Preprotein translocase subunit DUF892 PF05974.12 KUM61406.1 - 0.019 15.0 4.7 22 5.0 0.0 4.6 2 1 1 5 5 5 0 Domain of unknown function (DUF892) UPF0051 PF01458.17 KUM61406.1 - 0.024 14.4 5.8 23 4.6 0.1 3.9 2 1 2 4 4 4 0 Uncharacterized protein family (UPF0051) DUF1843 PF08898.10 KUM61406.1 - 0.045 14.2 14.1 16 6.1 1.5 5.0 4 1 1 5 5 5 0 Domain of unknown function (DUF1843) HicA_toxin PF07927.12 KUM61406.1 - 0.16 12.0 0.0 2.8e+02 1.6 0.0 3.9 4 0 0 4 4 4 0 HicA toxin of bacterial toxin-antitoxin, RTC4 PF14474.6 KUM61406.1 - 0.26 11.4 2.2 3.9 7.7 0.7 2.7 2 1 1 3 3 3 0 RTC4-like domain CholecysA-Rec_N PF09193.10 KUM61406.1 - 0.71 9.9 7.2 55 3.9 0.1 4.0 4 0 0 4 4 4 0 Cholecystokinin A receptor, N-terminal Trp_syntA PF00290.20 KUM61407.1 - 9.1e-95 316.4 0.0 1.8e-94 315.4 0.0 1.5 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KUM61407.1 - 2.5e-51 174.8 1.3 4e-51 174.2 1.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ATP-synt_ab PF00006.25 KUM61408.1 - 1.9e-69 233.6 0.0 2.6e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KUM61408.1 - 4.3e-12 46.4 0.5 8e-12 45.5 0.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Peptidase_S10 PF00450.22 KUM61409.1 - 2.8e-79 267.5 0.1 4.2e-79 266.9 0.1 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase ADH_zinc_N PF00107.26 KUM61411.1 - 1.3e-24 86.6 0.8 2e-24 86.0 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM61411.1 - 2.9e-13 51.0 0.0 6.4e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM61411.1 - 0.0034 17.3 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KUM61411.1 - 0.019 14.4 0.9 0.035 13.5 0.9 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DUF5595 PF18077.1 KUM61412.1 - 0.074 13.1 0.2 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Glyco_hydro_59M PF17387.2 KUM61413.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 central domain DnaJ PF00226.31 KUM61414.1 - 1.5e-19 69.9 0.4 1.5e-19 69.9 0.4 2.2 2 0 0 2 2 2 1 DnaJ domain DUF493 PF04359.14 KUM61414.1 - 0.083 13.5 0.0 0.3 11.7 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF493) zf-C4H2 PF10146.9 KUM61414.1 - 0.19 12.0 6.3 0.35 11.1 6.3 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein RR_TM4-6 PF06459.12 KUM61414.1 - 0.32 10.8 12.3 0.015 15.2 6.1 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 EMC3_TMCO1 PF01956.16 KUM61414.1 - 7.9 6.2 5.9 16 5.2 5.9 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Inv-AAD PF18785.1 KUM61415.1 - 5.1e-45 152.5 0.0 6.5e-45 152.1 0.0 1.2 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KUM61415.1 - 1.2e-10 41.2 0.0 4.5e-10 39.3 0.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 KUM61415.1 - 0.00022 21.2 0.0 0.00037 20.4 0.0 1.3 1 1 0 1 1 1 1 APOBEC-like N-terminal domain GYF PF02213.16 KUM61416.1 - 1.2e-18 66.5 0.4 2.5e-18 65.5 0.4 1.6 1 0 0 1 1 1 1 GYF domain Homeodomain PF00046.29 KUM61416.1 - 3.4 7.6 5.6 1.4 8.8 2.6 1.9 2 0 0 2 2 2 0 Homeodomain Usp PF00582.26 KUM61417.1 - 2e-15 57.6 2.4 6.9e-09 36.3 0.1 3.3 2 1 0 2 2 2 2 Universal stress protein family MARVEL PF01284.23 KUM61419.1 - 6e-20 71.7 10.6 7.2e-20 71.5 10.6 1.0 1 0 0 1 1 1 1 Membrane-associating domain adh_short PF00106.25 KUM61420.1 - 2.9e-23 82.3 0.3 3.7e-23 82.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM61420.1 - 5.8e-15 55.7 0.2 9.3e-15 55.0 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KUM61420.1 - 1.3e-14 54.3 0.1 1.6e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KUM61420.1 - 9.5e-09 34.8 0.0 1.3e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KUM61420.1 - 2e-07 30.7 0.1 7.1e-07 28.9 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM61420.1 - 0.00062 19.3 0.0 0.00079 18.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KUM61420.1 - 0.0073 16.2 0.6 0.011 15.7 0.6 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Prenyltransf PF01255.19 KUM61421.1 - 2e-48 164.8 0.0 2.4e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase HD_5 PF13487.6 KUM61421.1 - 0.13 12.5 0.0 0.97 9.7 0.0 2.1 2 0 0 2 2 2 0 HD domain Stc1 PF12898.7 KUM61422.1 - 5.1e-08 33.3 5.5 8e-08 32.7 5.5 1.2 1 0 0 1 1 1 1 Stc1 domain ZZ PF00569.17 KUM61422.1 - 1.4 8.8 7.5 0.18 11.6 1.6 2.0 1 1 1 2 2 2 0 Zinc finger, ZZ type Pkinase PF00069.25 KUM61423.1 - 4e-57 193.6 0.0 6.1e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM61423.1 - 1.2e-30 106.7 0.0 6.9e-29 100.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KUM61423.1 - 0.0015 17.6 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KUM61423.1 - 0.097 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Stn1 PF10451.9 KUM61424.1 - 3.4e-12 45.9 0.1 1.8e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 KUM61424.1 - 1.2e-05 25.2 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain baeRF_family5 PF18846.1 KUM61424.1 - 0.04 14.1 1.1 0.07 13.3 1.1 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 Cytochrom_C PF00034.21 KUM61426.1 - 6.6e-13 49.6 0.1 8.3e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KUM61426.1 - 3.3e-08 33.7 2.8 2e-07 31.2 2.8 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KUM61426.1 - 0.00031 20.5 0.1 0.00071 19.3 0.1 1.5 2 0 0 2 2 2 1 Cytochrome c-550 domain Baculo_PEP_C PF04513.12 KUM61427.1 - 0.28 11.2 2.4 0.64 10.1 0.3 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNase_PH PF01138.21 KUM61428.1 - 2.5e-11 44.2 0.0 9.3e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KUM61428.1 - 0.011 15.8 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Fmp27 PF10344.9 KUM61429.1 - 0.079 11.1 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Ank_4 PF13637.6 KUM61430.1 - 2.5e-19 69.4 0.9 1.1e-07 32.3 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KUM61430.1 - 4.8e-16 59.1 0.3 1.2e-08 35.4 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KUM61430.1 - 6.6e-14 51.6 1.6 0.0041 17.5 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KUM61430.1 - 3.5e-11 42.3 0.1 0.007 16.8 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KUM61430.1 - 4.8e-10 39.5 0.3 0.0049 17.2 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF1147 PF06615.11 KUM61430.1 - 0.087 12.9 0.1 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1147) Nop14 PF04147.12 KUM61431.1 - 0.0093 14.2 2.2 0.011 14.1 2.2 1.0 1 0 0 1 1 1 1 Nop14-like family ARD PF03079.14 KUM61432.1 - 2.3e-45 154.6 0.1 2.8e-45 154.3 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KUM61432.1 - 1.5e-10 40.6 0.0 2.6e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KUM61432.1 - 1.8e-06 27.9 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KUM61432.1 - 0.016 14.8 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 KUM61432.1 - 0.063 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Endonuc_BglI PF14562.6 KUM61434.1 - 0.094 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BglI MAGP PF05507.11 KUM61434.1 - 0.097 13.1 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) Pkinase PF00069.25 KUM61436.1 - 2.8e-63 213.8 0.0 4e-63 213.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM61436.1 - 5e-27 94.8 0.0 6.6e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM61436.1 - 0.00031 20.2 0.0 0.00064 19.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KUM61436.1 - 0.0049 16.8 0.3 0.01 15.7 0.1 1.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KUM61436.1 - 0.018 14.0 0.0 0.039 12.9 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KUM61436.1 - 0.059 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Abhydrolase_6 PF12697.7 KUM61438.1 - 2.4e-15 57.8 0.2 2.8e-15 57.6 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM61438.1 - 0.042 13.1 0.0 0.2 10.9 0.0 2.1 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Aldo_ket_red PF00248.21 KUM61439.1 - 3.2e-45 154.6 0.0 3.6e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GIDA PF01134.22 KUM61441.1 - 6.9e-154 512.7 0.0 8.5e-154 512.4 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KUM61441.1 - 5.6e-68 229.3 0.0 7.6e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 KUM61441.1 - 6.8e-06 25.7 1.0 1e-05 25.1 1.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM61441.1 - 2.2e-05 23.8 0.7 4.6e-05 22.8 0.4 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM61441.1 - 0.001 18.3 2.1 0.001 18.3 2.1 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KUM61441.1 - 0.0031 16.8 0.2 0.0063 15.8 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KUM61441.1 - 0.023 13.4 0.5 0.2 10.3 0.3 2.1 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 KUM61441.1 - 0.19 10.7 0.0 0.34 9.9 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Gti1_Pac2 PF09729.9 KUM61442.1 - 3e-63 213.2 0.0 7.7e-63 211.8 0.0 1.6 2 0 0 2 2 2 1 Gti1/Pac2 family MMM1 PF10296.9 KUM61443.1 - 3.6e-131 437.1 0.0 4.4e-131 436.9 0.0 1.0 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 FAD_binding_4 PF01565.23 KUM61444.1 - 4.4e-21 75.1 1.0 4.4e-21 75.1 1.0 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KUM61444.1 - 5e-13 48.9 1.0 1e-12 47.9 1.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KUM61444.1 - 0.057 12.8 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Epimerase PF01370.21 KUM61445.1 - 7.9e-14 51.7 0.0 1.6e-13 50.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KUM61445.1 - 5.8e-09 36.1 0.0 1.6e-08 34.7 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KUM61445.1 - 3.7e-08 32.7 0.0 4.7e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KUM61445.1 - 2.1e-05 24.0 0.0 0.13 11.7 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase NmrA PF05368.13 KUM61445.1 - 3.4e-05 23.5 0.0 5.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KUM61445.1 - 3.5e-05 23.3 0.0 4.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KUM61445.1 - 0.0067 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KUM61445.1 - 0.025 13.8 0.0 0.33 10.1 0.0 2.1 1 1 0 1 1 1 0 Male sterility protein p450 PF00067.22 KUM61446.1 - 5.1e-58 196.9 0.0 6.4e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KUM61447.1 - 1.1e-18 67.4 0.2 8.6e-18 64.5 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM61447.1 - 5.2e-11 42.6 0.0 8.6e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KUM61447.1 - 7.1e-06 25.6 0.1 1.3e-05 24.8 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KUM61447.1 - 0.00049 20.1 0.2 0.0061 16.5 0.1 2.1 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KUM61447.1 - 0.064 12.6 0.4 0.51 9.7 0.4 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase ATP-synt_F PF01990.17 KUM61447.1 - 0.19 12.0 0.0 0.43 10.9 0.0 1.5 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit p450 PF00067.22 KUM61448.1 - 2.2e-57 194.8 0.0 2.3e-57 194.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hydantoinase_B PF02538.14 KUM61450.1 - 2.4e-126 422.2 0.0 3.4e-126 421.7 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KUM61450.1 - 9.1e-91 304.1 3.0 4e-90 302.0 1.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KUM61450.1 - 4.4e-49 166.6 0.1 2e-46 157.9 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 KUM61450.1 - 0.00012 20.9 2.5 0.13 10.8 0.1 3.0 3 0 0 3 3 3 2 MutL protein FtsA PF14450.6 KUM61450.1 - 0.00083 19.7 0.2 2 8.9 0.1 2.8 2 0 0 2 2 2 2 Cell division protein FtsA Ppx-GppA PF02541.16 KUM61450.1 - 0.11 12.0 0.3 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Methyltransf_23 PF13489.6 KUM61451.1 - 1.7e-08 34.5 0.0 2.1e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM61451.1 - 4e-07 30.7 0.0 7.8e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM61451.1 - 1.1e-06 29.3 0.0 2.8e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM61451.1 - 1.9e-05 24.5 0.0 5.9e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM61451.1 - 4.8e-05 23.9 0.0 0.00011 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM61451.1 - 0.016 14.5 0.0 0.059 12.7 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Trp_DMAT PF11991.8 KUM61452.1 - 6.9e-94 315.2 0.0 8e-94 315.0 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Lyase_aromatic PF00221.19 KUM61453.1 - 6.1e-148 493.3 1.1 6.1e-148 493.3 1.1 1.5 2 0 0 2 2 2 1 Aromatic amino acid lyase Glycos_transf_N PF04413.16 KUM61453.1 - 0.087 12.5 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) UreF PF01730.16 KUM61454.1 - 2.4e-22 80.0 0.5 4.1e-22 79.2 0.5 1.3 1 0 0 1 1 1 1 UreF BRE1 PF08647.11 KUM61455.1 - 7.7e-27 93.2 8.9 7.7e-27 93.2 8.9 6.3 4 2 2 6 6 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KUM61455.1 - 1.4e-09 37.6 6.8 2.4e-09 36.9 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KUM61455.1 - 2.8e-09 36.7 8.3 4.8e-09 35.9 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM61455.1 - 4.3e-08 32.9 10.2 7.6e-08 32.1 10.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KUM61455.1 - 8e-08 32.2 5.9 1.5e-07 31.3 5.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KUM61455.1 - 1.3e-07 31.8 7.5 2.2e-07 31.1 7.5 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KUM61455.1 - 2.1e-07 30.7 7.6 3.4e-07 30.0 7.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KUM61455.1 - 2.9e-06 27.1 10.1 4.9e-06 26.4 10.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DUF745 PF05335.13 KUM61455.1 - 0.00021 21.0 7.7 0.00021 21.0 7.7 3.8 2 1 2 4 4 4 1 Protein of unknown function (DUF745) DUF1272 PF06906.11 KUM61455.1 - 0.0011 19.0 5.3 0.0025 17.9 5.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) KxDL PF10241.9 KUM61455.1 - 0.004 17.4 1.6 0.004 17.4 1.6 5.3 3 2 0 5 5 5 1 Uncharacterized conserved protein zf-C3HC4_4 PF15227.6 KUM61455.1 - 0.0041 17.3 6.4 0.0074 16.4 6.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KUM61455.1 - 0.0085 16.4 6.3 0.026 14.8 6.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KUM61455.1 - 0.024 14.4 7.2 0.25 11.2 8.0 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KUM61455.1 - 0.027 14.6 5.8 0.054 13.6 5.8 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF223 PF02721.14 KUM61455.1 - 0.065 13.5 0.9 0.4 11.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF223 Zn_ribbon_17 PF17120.5 KUM61455.1 - 0.12 12.0 3.5 0.21 11.2 3.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PLAC9 PF15205.6 KUM61455.1 - 0.12 12.8 1.4 5.4 7.5 0.0 3.4 4 0 0 4 4 3 0 Placenta-specific protein 9 DZR PF12773.7 KUM61455.1 - 0.23 11.5 6.9 0.45 10.6 6.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-Nse PF11789.8 KUM61455.1 - 0.35 10.7 4.0 0.72 9.7 4.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-H2C2_2 PF13465.6 KUM61455.1 - 0.39 11.2 2.9 4 8.0 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger double domain ATG16 PF08614.11 KUM61455.1 - 0.49 10.6 61.3 0.27 11.5 25.6 3.7 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) FYVE PF01363.21 KUM61455.1 - 0.51 10.5 11.5 0.65 10.2 5.8 2.5 1 1 1 2 2 2 0 FYVE zinc finger Filament PF00038.21 KUM61455.1 - 0.56 9.7 46.9 1.4e+03 -1.4 46.9 3.4 1 1 0 1 1 1 0 Intermediate filament protein zf-C2HC_2 PF13913.6 KUM61455.1 - 0.92 9.5 6.4 1.4 8.9 2.0 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TMF_TATA_bd PF12325.8 KUM61455.1 - 1 9.6 50.2 1.5 9.0 2.7 6.4 1 1 6 7 7 7 0 TATA element modulatory factor 1 TATA binding HALZ PF02183.18 KUM61455.1 - 1.6 9.0 16.1 14 6.0 0.4 5.6 5 0 0 5 5 5 0 Homeobox associated leucine zipper zf-ribbon_3 PF13248.6 KUM61455.1 - 1.7 8.2 4.6 2.8 7.5 3.7 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Rad50_zn_hook PF04423.14 KUM61455.1 - 8.8 6.3 7.7 1.6 8.6 0.1 3.8 4 0 0 4 4 3 0 Rad50 zinc hook motif TBCC_N PF16752.5 KUM61456.1 - 0.072 13.5 6.4 0.13 12.7 1.2 2.2 1 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Myb_DNA-bind_7 PF15963.5 KUM61457.1 - 8.4e-29 99.3 0.2 8.4e-29 99.3 0.2 1.9 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KUM61457.1 - 1.2e-05 25.4 0.0 2.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SARAF PF06682.12 KUM61458.1 - 3.7e-98 329.2 1.1 6e-98 328.5 1.1 1.3 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis XFP_C PF09363.10 KUM61458.1 - 0.27 10.7 0.0 0.39 10.1 0.0 1.1 1 0 0 1 1 1 0 XFP C-terminal domain Lipoxygenase PF00305.19 KUM61459.1 - 2.9e-14 52.5 0.0 2.9e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Lipoxygenase W2 PF02020.18 KUM61459.1 - 0.099 12.8 0.4 18 5.6 0.0 3.0 2 1 1 3 3 3 0 eIF4-gamma/eIF5/eIF2-epsilon Lipoxygenase PF00305.19 KUM61460.1 - 1.5e-17 63.3 0.1 5.8e-15 54.8 0.1 2.2 2 0 0 2 2 2 2 Lipoxygenase NMD3 PF04981.13 KUM61461.1 - 1.1e-77 260.8 6.1 1.6e-77 260.3 6.1 1.2 1 0 0 1 1 1 1 NMD3 family HypA PF01155.19 KUM61461.1 - 3.1 7.8 10.1 2.3 8.3 0.1 2.9 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Fungal_trans_2 PF11951.8 KUM61463.1 - 2.6e-05 23.2 0.1 2.6e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1889 PF08986.10 KUM61463.1 - 0.088 13.2 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1889) FAD_binding_3 PF01494.19 KUM61464.1 - 0.036 13.3 0.0 0.65 9.2 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KUM61464.1 - 0.065 12.5 0.5 0.094 11.9 0.5 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM61464.1 - 0.12 12.6 0.2 0.26 11.5 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Mannosyl_trans3 PF11051.8 KUM61465.1 - 4e-63 213.3 0.0 3.4e-38 131.6 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative EF-hand_6 PF13405.6 KUM61466.1 - 1.4e-05 24.6 0.0 2.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KUM61466.1 - 2.7e-05 23.4 0.0 4.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KUM61466.1 - 3.5e-05 23.1 0.0 5.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KUM61466.1 - 0.00075 19.9 0.0 0.0009 19.7 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KUM61467.1 - 3.8e-19 66.7 13.3 7.7e-08 31.3 1.2 3.1 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KUM61467.1 - 3.6e-15 56.1 5.8 3.3e-13 49.9 1.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KUM61467.1 - 2.4e-13 48.9 6.9 2.4e-05 23.9 0.2 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KUM61467.1 - 5.4e-12 44.6 8.5 3.8e-06 26.2 0.8 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KUM61467.1 - 4.1e-10 39.4 9.1 6.3e-05 22.7 0.6 2.9 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KUM61467.1 - 0.00016 21.5 7.0 0.13 12.3 0.7 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KUM61467.1 - 0.00024 21.4 0.1 0.00045 20.5 0.1 1.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KUM61467.1 - 0.062 13.6 0.1 0.44 10.9 0.1 2.1 2 1 0 2 2 2 0 EF-hand domain Fungal_trans_2 PF11951.8 KUM61468.1 - 5.2e-49 167.1 1.9 6e-49 166.9 1.9 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ndc1_Nup PF09531.10 KUM61469.1 - 1.7 7.2 4.4 2.1 7.0 4.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Aminotran_1_2 PF00155.21 KUM61471.1 - 5.3e-38 131.1 0.0 8.3e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KUM61471.1 - 7.5e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KUM61471.1 - 8.7e-05 21.6 0.0 0.00015 20.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KUM61471.1 - 9.4e-05 21.1 0.0 0.00016 20.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Peptidase_M22 PF00814.25 KUM61472.1 - 7.3e-86 288.2 0.0 8.6e-86 288.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KUM61472.1 - 0.017 14.8 0.0 0.55 9.8 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus AMPK1_CBM PF16561.5 KUM61473.1 - 2.2e-28 98.3 0.0 3.6e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KUM61473.1 - 6.8e-25 87.1 3.1 1e-24 86.6 1.0 2.5 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain SET PF00856.28 KUM61474.1 - 7.7e-23 81.7 0.0 1.5e-22 80.7 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KUM61474.1 - 1.7e-10 41.7 0.5 1.1e-09 39.1 0.1 2.2 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Herpes_DNAp_acc PF04929.12 KUM61475.1 - 0.84 8.5 6.9 1.2 8.1 6.9 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor adh_short PF00106.25 KUM61477.1 - 1.6e-28 99.5 1.1 2.3e-28 99.0 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM61477.1 - 2.8e-19 69.6 1.4 3.8e-19 69.2 1.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM61477.1 - 2.5e-08 34.0 0.6 4.4e-08 33.2 0.6 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM61477.1 - 3.1e-08 33.4 0.2 1.4e-06 28.0 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KUM61477.1 - 2.3e-05 24.3 3.4 4.8e-05 23.3 3.4 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KUM61477.1 - 0.0072 15.9 0.4 0.011 15.3 0.4 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KUM61477.1 - 0.027 13.5 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KUM61477.1 - 0.096 12.9 1.4 0.17 12.1 1.1 1.7 1 1 0 1 1 1 0 TrkA-N domain Glyoxalase PF00903.25 KUM61478.1 - 4.3e-05 23.7 0.0 5.4e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KUM61478.1 - 0.049 14.4 0.0 0.062 14.1 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain Ank_2 PF12796.7 KUM61479.1 - 8.1e-49 164.1 21.7 4.6e-14 52.8 0.5 5.4 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KUM61479.1 - 3.5e-26 90.4 18.4 0.0033 17.8 0.1 9.8 8 1 1 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 KUM61479.1 - 1.8e-23 82.5 5.2 2.1e-06 28.1 0.0 6.7 2 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM61479.1 - 7.9e-20 68.9 13.2 0.057 14.0 0.0 10.2 9 1 1 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 KUM61479.1 - 1.5e-16 60.2 12.8 0.1 13.0 0.1 8.7 4 3 4 8 8 8 7 Ankyrin repeats (many copies) NACHT PF05729.12 KUM61479.1 - 3.5e-06 27.0 0.0 7.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TsaE PF02367.17 KUM61479.1 - 0.0067 16.4 0.0 0.022 14.8 0.0 1.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 KUM61479.1 - 0.033 13.4 0.4 0.24 10.6 0.2 2.2 2 0 0 2 2 2 0 KAP family P-loop domain LolA_2 PF16584.5 KUM61479.1 - 0.9 9.4 8.7 35 4.3 0.1 5.0 1 1 4 5 5 5 0 Outer membrane lipoprotein carrier protein LolA DJ-1_PfpI PF01965.24 KUM61480.1 - 7e-15 55.2 0.0 1.1e-14 54.5 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family Fungal_trans PF04082.18 KUM61481.1 - 1.4e-05 24.2 1.0 6.5e-05 22.1 0.4 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain ABC1 PF03109.16 KUM61482.1 - 2.2e-34 118.2 0.0 7.7e-34 116.4 0.0 2.0 2 0 0 2 2 2 1 ABC1 family GrpB PF04229.14 KUM61483.1 - 5.3e-50 169.7 0.0 6.7e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 GrpB protein Med25_NR-box PF11244.8 KUM61483.1 - 0.032 14.6 0.1 0.065 13.6 0.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing EPL1 PF10513.9 KUM61484.1 - 1.8e-23 83.7 0.4 1.8e-23 83.7 0.4 3.0 3 1 0 3 3 3 1 Enhancer of polycomb-like SET PF00856.28 KUM61487.1 - 2.8e-14 53.8 0.0 1.3e-13 51.7 0.0 2.2 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 KUM61487.1 - 9e-07 28.5 0.0 0.35 11.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KUM61487.1 - 2.4e-06 27.1 0.0 0.0025 17.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KUM61487.1 - 0.0006 20.4 1.3 0.0057 17.3 0.0 2.7 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KUM61487.1 - 0.0022 18.7 0.1 6.6 7.8 0.1 3.2 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KUM61487.1 - 0.0025 17.9 0.2 1.9 8.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KUM61487.1 - 0.0073 16.3 0.2 4.7 7.5 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM61487.1 - 0.047 13.9 0.3 0.15 12.3 0.3 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 KUM61487.1 - 0.051 13.6 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Putative TPR-like repeat TPR_6 PF13174.6 KUM61487.1 - 0.098 13.3 0.0 13 6.7 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KUM61487.1 - 0.1 13.1 0.4 0.79 10.3 0.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KUM61487.1 - 0.39 11.0 2.1 15 6.0 0.0 3.4 2 1 0 3 3 3 0 Tetratricopeptide repeat DUF1857 PF08982.11 KUM61488.1 - 1.5e-45 154.6 0.0 1.7e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) SAS4 PF15460.6 KUM61489.1 - 3e-30 104.2 7.3 7.1e-30 103.0 7.3 1.7 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.6 KUM61489.1 - 0.012 16.3 0.4 0.012 16.3 0.4 4.4 5 2 0 5 5 5 0 PEHE domain Acetyltransf_4 PF13420.7 KUM61490.1 - 2.5e-05 24.5 0.0 0.0055 16.8 0.0 2.4 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM61490.1 - 0.06 13.6 0.0 0.08 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HAT PF02184.16 KUM61491.1 - 0.025 14.6 0.1 0.065 13.2 0.1 1.7 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat DUF2156 PF09924.9 KUM61492.1 - 1.2e-28 100.0 0.0 2e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Ribonuc_L-PSP PF01042.21 KUM61494.1 - 3.5e-18 65.7 0.0 4.8e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4813 PF16072.5 KUM61494.1 - 0.1 12.2 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DZR PF12773.7 KUM61495.1 - 5.7e-05 23.0 2.5 0.00014 21.8 2.5 1.7 1 0 0 1 1 1 1 Double zinc ribbon Nudix_N_2 PF14803.6 KUM61495.1 - 0.0021 17.9 7.5 0.098 12.6 0.4 2.6 1 1 1 2 2 2 2 Nudix N-terminal zinc_ribbon_2 PF13240.6 KUM61495.1 - 0.0021 17.7 6.9 0.36 10.6 0.3 2.9 3 0 0 3 3 3 2 zinc-ribbon domain zf-NADH-PPase PF09297.11 KUM61495.1 - 0.0031 17.1 6.6 0.22 11.2 1.9 2.5 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_15 PF17032.5 KUM61495.1 - 0.0032 18.2 0.2 0.0068 17.1 0.2 1.6 1 0 0 1 1 1 1 zinc-ribbon family EphA2_TM PF14575.6 KUM61495.1 - 0.056 14.3 0.0 0.45 11.4 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1272 PF06906.11 KUM61495.1 - 0.17 12.0 1.9 0.43 10.7 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Syndecan PF01034.20 KUM61495.1 - 0.23 11.4 0.3 0.23 11.4 0.3 2.0 2 0 0 2 2 2 0 Syndecan domain YhfH PF14149.6 KUM61495.1 - 0.27 11.2 4.2 0.62 10.1 0.2 2.4 1 1 1 2 2 2 0 YhfH-like protein zf-ribbon_3 PF13248.6 KUM61495.1 - 2 7.9 9.6 0.45 10.0 5.1 2.3 2 1 0 2 2 2 0 zinc-ribbon domain DUF35_N PF12172.8 KUM61495.1 - 2.5 8.0 7.2 4.6 7.2 5.3 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) HypA PF01155.19 KUM61495.1 - 2.7 8.0 4.3 1.7 8.7 2.3 1.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA AA_permease_2 PF13520.6 KUM61496.1 - 3.6e-46 157.9 41.0 4.2e-46 157.6 41.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM61496.1 - 1.4e-14 53.5 31.3 1.8e-14 53.3 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease PAS_9 PF13426.7 KUM61497.1 - 7.9e-15 55.0 0.0 1.5e-13 50.8 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KUM61497.1 - 8.3e-05 22.6 0.0 0.00075 19.5 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 KUM61497.1 - 0.044 14.0 0.0 2 8.7 0.0 2.6 2 0 0 2 2 2 0 PAS fold Pal1 PF08316.11 KUM61498.1 - 1.4e-09 38.8 0.1 1.4e-09 38.8 0.1 1.7 2 1 0 2 2 2 1 Pal1 cell morphology protein HVSL PF09749.9 KUM61499.1 - 5.4e-83 278.1 0.0 6.2e-83 277.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein Aa_trans PF01490.18 KUM61500.1 - 1.4e-39 135.9 39.1 1.7e-39 135.7 39.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3188 PF11384.8 KUM61500.1 - 8.5 6.2 7.9 2.2 8.0 1.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) DUF3807 PF12720.7 KUM61501.1 - 1.1e-36 126.9 11.1 1.7e-36 126.2 11.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) CDC45 PF02724.14 KUM61501.1 - 0.37 9.0 7.5 0.39 9.0 7.5 1.0 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 KUM61503.1 - 7e-13 48.2 47.9 9.5e-07 28.1 20.7 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily SpoVAB PF13782.6 KUM61503.1 - 2.3 8.5 9.4 0.12 12.7 1.7 2.7 2 1 0 2 2 2 0 Stage V sporulation protein AB LapA_dom PF06305.11 KUM61503.1 - 3.4 7.5 8.9 0.28 11.0 1.1 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Ferritin_2 PF13668.6 KUM61504.1 - 5.4e-10 39.6 0.0 7.4e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF3568 PF12092.8 KUM61504.1 - 0.091 12.8 0.9 0.16 12.0 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Peptidase_S10 PF00450.22 KUM61505.1 - 2.9e-76 257.6 0.0 3.9e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_3_C PF01915.22 KUM61507.1 - 1.2e-55 188.6 0.1 2.1e-55 187.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KUM61507.1 - 1.1e-42 146.6 0.0 1.6e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KUM61507.1 - 1.2e-27 95.8 0.0 2.3e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3828 PF12883.7 KUM61508.1 - 0.1 13.0 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) HlyIII PF03006.20 KUM61509.1 - 6e-40 137.3 10.9 6.8e-40 137.2 10.9 1.0 1 0 0 1 1 1 1 Haemolysin-III related ATPase_gene1 PF09527.10 KUM61509.1 - 3.2 8.0 7.8 1.6 8.9 3.5 2.7 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Lipase_GDSL_2 PF13472.6 KUM61510.1 - 2e-15 57.7 0.1 2.9e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KUM61510.1 - 1.9e-10 41.1 0.0 2.4e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KUM61510.1 - 0.019 15.1 0.1 0.062 13.4 0.1 2.1 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family GspL_C PF12693.7 KUM61510.1 - 0.046 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 GspL periplasmic domain ATP-grasp_2 PF08442.10 KUM61511.1 - 8.2e-49 165.9 0.0 1.2e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KUM61511.1 - 1.1e-07 31.8 0.1 3.2e-07 30.3 0.1 1.7 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 KUM61511.1 - 3.7e-07 29.8 0.0 6.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KUM61511.1 - 0.012 15.1 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Ligase_CoA PF00549.19 KUM61512.1 - 0.00093 19.0 0.2 0.001 18.9 0.2 1.1 1 0 0 1 1 1 1 CoA-ligase RRM_1 PF00076.22 KUM61514.1 - 1.4e-23 82.5 0.0 1.6e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KUM61514.1 - 0.0043 17.1 0.0 0.0077 16.3 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 KUM61514.1 - 0.025 14.6 0.0 0.03 14.4 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif Limkain-b1 PF11608.8 KUM61514.1 - 0.11 12.6 0.1 0.12 12.4 0.1 1.3 1 1 0 1 1 1 0 Limkain b1 RRM_5 PF13893.6 KUM61514.1 - 0.13 11.9 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KUM61514.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif Gelsolin PF00626.22 KUM61516.1 - 8e-38 128.2 0.7 1.5e-13 50.4 0.1 3.2 3 0 0 3 3 3 3 Gelsolin repeat zf-H3C2 PF16721.5 KUM61516.1 - 0.16 12.4 0.1 2.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger like, probable DNA-binding NAD_binding_4 PF07993.12 KUM61518.1 - 7.2e-30 104.0 0.0 1.1e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KUM61518.1 - 1.6e-28 99.5 0.0 2.8e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KUM61518.1 - 6.8e-12 45.4 0.0 1.1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KUM61518.1 - 1.1e-08 35.2 0.0 3.5e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 KUM61518.1 - 0.004 16.3 0.0 0.0072 15.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KUM61518.1 - 0.01 15.3 0.0 0.039 13.4 0.0 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase KR PF08659.10 KUM61518.1 - 0.024 14.6 0.0 3.8 7.4 0.0 2.4 2 0 0 2 2 2 0 KR domain 3Beta_HSD PF01073.19 KUM61518.1 - 0.027 13.5 0.0 0.058 12.4 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KUM61518.1 - 0.15 11.1 0.0 2.2 7.3 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain AP_endonuc_2 PF01261.24 KUM61519.1 - 2e-26 92.8 0.5 2.9e-26 92.2 0.5 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Methyltransf_2 PF00891.18 KUM61521.1 - 1.1e-18 67.3 0.0 2.3e-18 66.3 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KUM61521.1 - 0.013 15.4 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain Dimerisation PF08100.11 KUM61521.1 - 0.13 12.3 0.9 0.46 10.5 0.9 2.0 1 1 0 1 1 1 0 Dimerisation domain BcrAD_BadFG PF01869.20 KUM61522.1 - 1.1e-11 44.8 2.1 4.1e-11 42.9 1.4 2.2 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.6 KUM61522.1 - 0.0018 18.3 0.0 0.012 15.7 0.0 2.4 1 1 0 1 1 1 1 SIS domain MFS_1 PF07690.16 KUM61523.1 - 4.3e-16 58.8 35.8 4.3e-16 58.8 35.8 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KUM61523.1 - 1.4e-09 37.9 3.7 1.4e-09 37.9 3.7 2.8 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 LapA_dom PF06305.11 KUM61523.1 - 2 8.3 0.0 2 8.3 0.0 3.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain ACTH_assoc PF16102.5 KUM61525.1 - 2.2 9.3 7.7 5.4 8.0 0.1 3.8 3 0 0 3 3 3 0 ACTH-associated domain Glyco_hydro_16 PF00722.21 KUM61526.1 - 8.1e-06 25.4 0.1 2.5e-05 23.8 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 CN_hydrolase PF00795.22 KUM61527.1 - 3.1e-46 157.8 0.0 3.8e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CIA30 PF08547.12 KUM61528.1 - 3.9e-37 127.7 0.0 5e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Glyco_hydro_76 PF03663.14 KUM61529.1 - 1.2e-142 475.8 26.9 1.5e-142 475.5 26.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 MFS_1 PF07690.16 KUM61530.1 - 4.4e-45 154.1 22.2 4.4e-45 154.1 22.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM61530.1 - 0.001 17.6 5.5 0.002 16.6 5.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KUM61531.1 - 1.2e-36 126.4 48.1 1.2e-36 126.4 48.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM61531.1 - 5.3e-08 32.2 17.3 5.3e-08 32.2 17.3 2.8 2 2 0 2 2 2 1 Sugar (and other) transporter adh_short PF00106.25 KUM61532.1 - 2.8e-17 62.8 0.0 3.7e-13 49.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM61532.1 - 3.7e-08 33.2 0.0 3.3e-07 30.1 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KUM61532.1 - 3.5e-06 27.0 0.2 5.7e-06 26.3 0.2 1.4 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KUM61532.1 - 0.019 14.9 0.1 0.034 14.0 0.1 1.3 1 0 0 1 1 1 0 KR domain Ribosomal_L12 PF00542.19 KUM61532.1 - 0.072 13.4 0.0 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain Aldo_ket_red PF00248.21 KUM61533.1 - 1.5e-66 224.6 0.0 1.7e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 KUM61534.1 - 7.8e-05 21.8 0.0 0.00014 21.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain YrzK PF17449.2 KUM61534.1 - 0.0029 17.9 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized YrzK-like COesterase PF00135.28 KUM61535.1 - 1e-80 272.1 0.0 1.2e-80 271.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KUM61535.1 - 9.1e-07 28.9 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KUM61535.1 - 0.094 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family F-box PF00646.33 KUM61536.1 - 0.0069 16.2 0.1 0.028 14.3 0.1 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KUM61536.1 - 0.01 15.7 0.2 0.025 14.5 0.2 1.7 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 KUM61536.1 - 0.034 14.0 0.1 0.07 13.0 0.1 1.5 1 0 0 1 1 1 0 F-box Dimerisation PF08100.11 KUM61538.1 - 0.00044 20.2 0.6 0.0015 18.5 0.5 2.0 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_2 PF00891.18 KUM61538.1 - 0.00098 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KUM61538.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_2 PF00891.18 KUM61539.1 - 4.7e-13 48.9 0.0 5.3e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase domain Ald_Xan_dh_C2 PF02738.18 KUM61539.1 - 0.24 9.8 0.0 0.26 9.7 0.0 1.0 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase SOG2 PF10428.9 KUM61540.1 - 0.0012 18.1 31.1 0.005 16.1 23.6 2.0 2 0 0 2 2 2 2 RAM signalling pathway protein Amnionless PF14828.6 KUM61540.1 - 0.025 13.4 0.9 0.032 13.1 0.9 1.2 1 0 0 1 1 1 0 Amnionless SPX PF03105.19 KUM61540.1 - 2 8.2 23.6 4.9 7.0 16.0 2.0 2 0 0 2 2 2 0 SPX domain DUF3533 PF12051.8 KUM61540.1 - 4.5 6.1 10.7 6.3 5.6 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) CiPC PF15800.5 KUM61540.1 - 6.8 6.3 30.9 2.6 7.7 18.7 2.1 2 0 0 2 2 2 0 Clock interacting protein circadian Utp14 PF04615.13 KUM61540.1 - 7.1 5.1 11.6 1.8 7.0 8.1 1.6 2 0 0 2 2 2 0 Utp14 protein Glyco_hydro_71 PF03659.14 KUM61541.1 - 6e-131 436.7 2.7 7.1e-131 436.5 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 MR_MLE_C PF13378.6 KUM61543.1 - 7e-57 192.5 0.1 9.1e-57 192.1 0.1 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KUM61543.1 - 5.6e-19 68.5 0.0 1e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF1990 PF09348.10 KUM61543.1 - 0.041 13.9 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) MAAL_C PF07476.11 KUM61543.1 - 0.083 12.0 0.0 0.28 10.3 0.0 1.9 2 1 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus FMN_dh PF01070.18 KUM61544.1 - 1.3e-113 379.6 0.1 1.6e-113 379.3 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KUM61544.1 - 8.3e-22 77.1 0.0 4.3e-21 74.8 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KUM61544.1 - 2.2e-06 27.1 0.0 4.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KUM61544.1 - 2.3e-05 23.6 0.2 0.00021 20.4 0.1 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 KUM61544.1 - 0.033 13.4 0.1 0.057 12.6 0.1 1.5 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase ThiG PF05690.14 KUM61544.1 - 0.055 12.8 0.1 10 5.4 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KUM61544.1 - 0.079 12.4 0.1 1.2 8.6 0.0 2.3 2 1 0 2 2 2 0 Histidine biosynthesis protein ApbA PF02558.16 KUM61545.1 - 3.7e-36 124.1 0.1 4.8e-36 123.7 0.1 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KUM61545.1 - 1.8e-30 105.7 0.0 2.9e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Sacchrp_dh_NADP PF03435.18 KUM61545.1 - 0.044 14.0 0.1 0.13 12.6 0.1 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF3433 PF11915.8 KUM61546.1 - 9.5e-32 109.3 24.4 3e-17 62.9 3.5 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) TauD PF02668.16 KUM61547.1 - 7.6e-52 176.7 0.0 1e-51 176.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KUM61548.1 - 1.2e-18 67.2 23.3 2.5e-18 66.1 23.1 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M10 PF00413.24 KUM61548.1 - 0.055 13.3 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Matrixin Ig_GlcNase PF18368.1 KUM61549.1 - 4.4e-31 107.1 2.6 3.2e-30 104.4 0.5 2.8 3 0 0 3 3 3 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 KUM61549.1 - 1.3e-13 51.6 0.5 1.5e-12 48.2 0.1 2.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 KUM61549.1 - 5.1e-07 30.2 0.9 1.9e-06 28.4 0.1 2.4 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KUM61549.1 - 0.00072 19.3 0.1 0.041 13.6 0.0 2.8 3 0 0 3 3 3 1 Ig-fold domain Big_5 PF13205.6 KUM61549.1 - 0.045 14.4 0.5 0.29 11.8 0.1 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain Glyco_hydro_2_C PF02836.17 KUM61549.1 - 0.12 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Cyclin PF08613.11 KUM61550.1 - 4.9e-13 49.8 0.0 7.4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KUM61550.1 - 6.3e-05 22.7 0.4 0.00011 21.9 0.0 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain TT_ORF2 PF02957.15 KUM61550.1 - 3.2 8.7 10.7 0.34 11.8 2.2 2.9 3 0 0 3 3 3 0 TT viral ORF2 DNA_pol_A_exo1 PF01612.20 KUM61551.1 - 3.1e-41 141.0 0.1 5.2e-41 140.3 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KUM61551.1 - 1.1e-28 99.7 0.3 6e-28 97.4 0.3 2.4 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 KUM61551.1 - 8.1e-11 41.8 0.2 3e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 HRDC domain RasGAP PF00616.19 KUM61552.1 - 8.8e-60 202.0 0.3 1.7e-59 201.0 0.0 1.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KUM61552.1 - 5.9e-31 107.4 0.7 5.9e-31 107.4 0.7 2.3 2 0 0 2 2 2 1 RasGAP C-terminus MarR PF01047.22 KUM61552.1 - 0.11 12.4 0.2 0.59 10.1 0.1 2.3 2 0 0 2 2 2 0 MarR family SGL PF08450.12 KUM61553.1 - 5.6e-08 32.7 0.5 2.9e-06 27.1 0.2 2.0 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KUM61553.1 - 0.19 11.9 0.3 25 5.1 0.0 3.4 2 1 1 3 3 3 0 NHL repeat PQQ PF01011.21 KUM61553.1 - 0.68 10.0 3.3 5.1 7.2 0.1 3.6 3 1 1 4 4 4 0 PQQ enzyme repeat Acetyltransf_1 PF00583.25 KUM61554.1 - 3.7e-15 56.2 0.0 3.9e-11 43.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KUM61554.1 - 1.7e-10 41.1 0.0 3.8e-10 40.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KUM61554.1 - 1.4e-09 38.0 0.0 1e-07 32.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KUM61554.1 - 7.6e-08 32.2 0.0 0.0023 17.9 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_3 PF13302.7 KUM61554.1 - 6.1e-06 26.9 0.0 8.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KUM61554.1 - 2e-05 24.7 0.0 0.00012 22.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KUM61554.1 - 0.00032 20.8 0.0 0.0006 19.9 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 KUM61554.1 - 0.0083 15.8 0.0 0.62 9.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KUM61554.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase LCAT PF02450.15 KUM61555.1 - 4e-107 358.8 0.0 4.8e-107 358.5 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase BAAT_C PF08840.11 KUM61555.1 - 0.045 13.7 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_2 PF01674.18 KUM61555.1 - 0.073 12.6 0.1 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 Lipase (class 2) DUF900 PF05990.12 KUM61555.1 - 0.16 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PAP2_3 PF14378.6 KUM61556.1 - 1.8e-24 86.5 13.2 1.8e-24 86.5 13.2 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KUM61556.1 - 1.3e-11 44.4 2.2 3.2e-11 43.1 2.2 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KUM61556.1 - 1.2 9.7 8.0 0.61 10.7 4.3 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal CRAL_TRIO PF00650.20 KUM61557.1 - 3.7e-36 124.2 0.0 5.2e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KUM61557.1 - 2.7e-09 37.1 0.5 6.9e-09 35.8 0.5 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KUM61557.1 - 0.0063 16.7 0.0 0.013 15.7 0.0 1.5 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Mis14 PF08641.12 KUM61558.1 - 4.8e-26 91.7 7.3 7.3e-26 91.1 6.3 1.8 2 0 0 2 2 2 1 Kinetochore protein Mis14 like DUF5314 PF17241.2 KUM61558.1 - 0.19 11.4 1.7 1.1 8.9 0.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5314) TEX19 PF15553.6 KUM61558.1 - 0.36 10.8 5.8 0.67 9.9 5.8 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 Pox_Ag35 PF03286.14 KUM61558.1 - 1 9.1 7.2 1.6 8.5 7.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Paf1 PF03985.13 KUM61558.1 - 3.5 6.5 14.3 6.2 5.7 12.6 1.9 2 0 0 2 2 2 0 Paf1 Pex24p PF06398.11 KUM61559.1 - 1.2e-05 24.5 10.8 2e-05 23.8 10.8 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PPR_2 PF13041.6 KUM61560.1 - 0.022 14.9 0.0 0.35 11.1 0.0 2.9 3 0 0 3 3 3 0 PPR repeat family PQ-loop PF04193.14 KUM61564.1 - 1.3e-37 127.3 11.1 4.7e-19 67.9 0.4 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 KUM61564.1 - 0.12 12.4 6.8 0.18 11.9 0.1 2.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange RVT_1 PF00078.27 KUM61565.1 - 1.5e-35 122.7 0.0 2.3e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KUM61565.1 - 0.069 13.9 0.1 0.29 11.9 0.1 2.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DUF1987 PF09345.10 KUM61565.1 - 0.071 12.8 0.0 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) DUF3435 PF11917.8 KUM61566.1 - 3.1e-147 490.9 0.0 4e-147 490.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) COLFI PF01410.18 KUM61566.1 - 0.035 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain T3SS_basalb_I PF17001.5 KUM61566.1 - 0.054 14.1 2.6 0.28 11.8 0.2 3.1 3 0 0 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI zf-C2H2_4 PF13894.6 KUM61566.1 - 0.71 10.9 5.2 3.5 8.7 0.6 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KUM61566.1 - 2.9 8.5 6.1 1.6 9.3 0.9 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Nup54_57_C PF18570.1 KUM61567.1 - 0.0067 16.0 0.2 0.019 14.6 0.2 1.8 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain MRFAP1 PF15155.6 KUM61567.1 - 0.0087 16.6 6.1 0.011 16.2 6.1 1.1 1 0 0 1 1 1 1 MORF4 family-associated protein1 BLOC1_2 PF10046.9 KUM61567.1 - 0.014 15.7 1.5 0.014 15.7 1.5 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-H PF05837.12 KUM61567.1 - 0.024 15.0 12.1 0.045 14.1 11.8 1.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Filament PF00038.21 KUM61567.1 - 0.038 13.6 9.8 0.046 13.3 9.8 1.1 1 0 0 1 1 1 0 Intermediate filament protein TolA_bind_tri PF16331.5 KUM61567.1 - 0.056 13.5 0.2 0.056 13.5 0.2 2.5 1 1 0 2 2 2 0 TolA binding protein trimerisation DUF4200 PF13863.6 KUM61567.1 - 0.063 13.7 14.7 0.11 12.8 14.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) HemX PF04375.14 KUM61567.1 - 0.16 11.3 7.8 0.19 11.0 7.8 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase CC2-LZ PF16516.5 KUM61567.1 - 0.23 11.8 11.0 0.19 12.1 1.8 2.1 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CdvA PF18822.1 KUM61567.1 - 0.23 11.3 10.2 0.033 14.0 3.1 2.1 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Prefoldin_2 PF01920.20 KUM61567.1 - 0.24 11.4 11.3 0.45 10.5 11.3 1.5 1 1 0 1 1 1 0 Prefoldin subunit YkyA PF10368.9 KUM61567.1 - 0.34 10.6 12.4 0.42 10.3 12.4 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Med9 PF07544.13 KUM61567.1 - 0.41 10.8 9.4 0.66 10.1 1.9 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Mod_r PF07200.13 KUM61567.1 - 0.43 10.7 11.9 3.6 7.7 11.8 1.9 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF5401 PF17380.2 KUM61567.1 - 0.94 7.5 8.9 0.97 7.4 8.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) FAM76 PF16046.5 KUM61567.1 - 3.3 7.0 10.4 26 4.1 10.7 1.8 1 1 0 1 1 1 0 FAM76 protein DivIC PF04977.15 KUM61567.1 - 4.8 7.0 13.9 1.9 8.3 0.3 2.6 1 1 2 3 3 3 0 Septum formation initiator MutS_V PF00488.21 KUM61569.1 - 3.2e-81 271.9 0.2 5.7e-81 271.0 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KUM61569.1 - 4.2e-38 131.5 0.4 1.1e-37 130.2 0.4 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 KUM61569.1 - 2.2e-17 63.6 0.1 7.3e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KUM61569.1 - 4e-17 62.4 2.3 7.4e-17 61.5 1.0 2.3 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.20 KUM61569.1 - 3.8e-15 56.1 0.0 2.8e-14 53.3 0.0 2.3 2 0 0 2 2 2 1 MutS domain I SUR7 PF06687.12 KUM61569.1 - 0.085 12.5 0.0 0.42 10.2 0.0 2.1 2 1 0 2 2 2 0 SUR7/PalI family AsiA PF09010.10 KUM61569.1 - 0.15 12.2 0.0 2.4 8.3 0.0 2.7 2 0 0 2 2 2 0 Anti-Sigma Factor A DUF3168 PF11367.8 KUM61569.1 - 0.15 12.2 0.1 0.52 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3168) UPF0203 PF05254.12 KUM61570.1 - 1.1e-26 92.8 0.9 1.3e-26 92.6 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KUM61570.1 - 0.00018 21.8 0.5 0.00038 20.7 0.5 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KUM61570.1 - 0.0016 18.4 1.4 0.018 15.0 0.1 2.1 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 KUM61570.1 - 0.0048 17.1 1.5 1.3 9.2 0.1 2.1 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein DUF5339 PF17274.2 KUM61570.1 - 0.3 11.9 4.0 3.1 8.7 0.4 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5339) Gpi1 PF05024.15 KUM61571.1 - 3e-78 262.2 8.5 5.5e-78 261.3 8.5 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Dor1 PF04124.12 KUM61572.1 - 1.2e-56 191.8 3.3 6.1e-46 156.7 2.9 2.4 2 0 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 KUM61572.1 - 9.7e-05 22.4 0.4 0.00028 20.9 0.4 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Acetyltransf_3 PF13302.7 KUM61573.1 - 3.8e-07 30.8 0.0 1.1e-06 29.3 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FeoB_associated PF12669.7 KUM61574.1 - 0.041 14.3 0.4 0.066 13.6 0.4 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Tubulin_C PF03953.17 KUM61574.1 - 0.057 13.6 0.0 0.068 13.3 0.0 1.1 1 0 0 1 1 1 0 Tubulin C-terminal domain DUF2441 PF10386.9 KUM61574.1 - 0.057 13.4 0.0 0.066 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2441) DC_STAMP PF07782.13 KUM61574.1 - 0.1 12.4 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 DC-STAMP-like protein Phosphoesterase PF04185.14 KUM61575.1 - 9.4e-59 199.4 3.7 1.7e-58 198.6 3.7 1.4 1 1 0 1 1 1 1 Phosphoesterase family Reticulon PF02453.17 KUM61577.1 - 0.052 13.5 1.1 0.065 13.2 1.1 1.1 1 0 0 1 1 1 0 Reticulon TMEM208_SND2 PF05620.11 KUM61577.1 - 0.14 12.0 0.9 0.19 11.5 0.9 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 His_Phos_1 PF00300.22 KUM61578.1 - 1.3e-29 103.3 0.0 3.4e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) P5-ATPase PF12409.8 KUM61578.1 - 0.016 15.3 0.4 0.086 12.9 0.0 2.4 2 0 0 2 2 2 0 P5-type ATPase cation transporter VIT1 PF01988.19 KUM61579.1 - 8.4e-62 208.8 1.2 1.1e-61 208.5 1.2 1.1 1 0 0 1 1 1 1 VIT family 7TMR-DISM_7TM PF07695.11 KUM61579.1 - 0.0086 16.0 2.9 0.013 15.4 2.9 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling Abhydrolase_9_N PF15420.6 KUM61579.1 - 0.032 14.2 0.4 0.057 13.4 0.4 1.4 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus PAC2 PF09754.9 KUM61579.1 - 0.049 13.6 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 PAC2 family FA_hydroxylase PF04116.13 KUM61579.1 - 0.4 11.0 2.5 0.91 9.9 0.2 2.1 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily SLATT_fungal PF18142.1 KUM61579.1 - 0.44 10.6 3.3 0.25 11.3 0.4 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain TPIP1 PF15338.6 KUM61581.1 - 0.066 13.3 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 p53-regulated apoptosis-inducing protein 1 Fungal_trans PF04082.18 KUM61582.1 - 4.6e-16 58.6 0.0 7.9e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4805 PF16063.5 KUM61582.1 - 0.21 10.9 3.8 0.36 10.1 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Fungal_trans PF04082.18 KUM61584.1 - 7.5e-19 67.8 0.1 1.1e-18 67.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3094 PF11293.8 KUM61584.1 - 0.12 12.1 0.6 3.1 7.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) Sugar_tr PF00083.24 KUM61585.1 - 5.9e-84 282.5 19.9 6.9e-84 282.3 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM61585.1 - 8.9e-17 61.0 26.1 1.6e-13 50.3 19.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3852 PF12963.7 KUM61585.1 - 0.11 12.8 0.9 0.24 11.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) Tetraspanin PF00335.20 KUM61585.1 - 0.19 11.4 7.1 0.4 10.4 7.1 1.6 1 0 0 1 1 1 0 Tetraspanin family His_Phos_2 PF00328.22 KUM61586.1 - 4e-48 164.7 0.0 4.7e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GCFC PF07842.12 KUM61587.1 - 5.1e-82 275.6 6.9 5.1e-82 275.6 6.9 1.4 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KUM61587.1 - 7e-18 64.3 1.0 1.5e-17 63.2 1.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KUM61587.1 - 7.9e-10 38.7 0.9 2.6e-09 37.0 0.9 1.9 1 0 0 1 1 1 1 G-patch domain Sod_Fe_C PF02777.18 KUM61588.1 - 9.2e-35 118.9 1.3 1e-34 118.7 0.2 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KUM61588.1 - 1.6e-29 102.2 2.0 2.9e-29 101.4 2.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain TF_Zn_Ribbon PF08271.12 KUM61589.1 - 0.065 12.8 0.5 12 5.5 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Zn_ribbon_SprT PF17283.2 KUM61590.1 - 0.041 13.8 1.0 0.065 13.2 1.0 1.3 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-H2C2_5 PF13909.6 KUM61590.1 - 0.38 10.6 8.2 1 9.1 0.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KUM61590.1 - 1.7 9.2 4.1 40 4.9 1.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain DUF2798 PF11391.8 KUM61590.1 - 2.4 8.3 4.2 3.7 7.6 3.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2798) Cnn_1N PF07989.11 KUM61591.1 - 4.1e-06 26.9 7.7 4.1e-06 26.9 7.7 2.2 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 YabA PF06156.13 KUM61591.1 - 0.18 12.5 3.5 0.66 10.6 3.5 2.0 1 0 0 1 1 1 0 Initiation control protein YabA Sld5 PF05916.11 KUM61592.1 - 3.3e-21 75.8 0.0 4.1e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein DJ-1_PfpI PF01965.24 KUM61593.1 - 1.5e-15 57.4 0.0 1.8e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 KUM61593.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.4 1 1 0 1 1 1 0 Glutamine amidotransferase class-I Rhabdo_ncap PF00945.18 KUM61595.1 - 0.03 13.2 0.2 0.063 12.2 0.2 1.4 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Transket_pyr PF02779.24 KUM61596.1 - 1.4e-65 220.3 0.0 2.3e-65 219.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KUM61596.1 - 3.6e-59 200.2 0.0 5.4e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KUM61596.1 - 1.2e-56 190.7 0.1 1.9e-56 190.0 0.1 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KUM61596.1 - 2.8e-18 65.2 0.7 2.8e-18 65.2 0.7 2.1 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Sugar_tr PF00083.24 KUM61597.1 - 5.1e-84 282.7 20.7 6.3e-84 282.4 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM61597.1 - 4.1e-25 88.5 53.7 1.8e-23 83.0 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5345 PF17280.2 KUM61597.1 - 0.3 11.1 2.7 7.2 6.7 0.2 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Gate PF07670.14 KUM61597.1 - 7.5 6.9 10.3 0.65 10.3 3.9 2.5 2 1 0 2 2 2 0 Nucleoside recognition Cation_efflux PF01545.21 KUM61598.1 - 2.5e-27 95.9 9.2 3.1e-27 95.6 9.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KUM61598.1 - 6.3e-11 42.2 0.2 1.1e-10 41.5 0.2 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter P22_Tail-4 PF11650.8 KUM61598.1 - 0.082 12.9 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 P22 tail accessory factor DUF423 PF04241.15 KUM61598.1 - 5.3 7.3 6.0 18 5.6 0.1 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF423) VIT1 PF01988.19 KUM61599.1 - 1.8e-63 214.3 6.8 2.1e-63 214.0 6.8 1.1 1 0 0 1 1 1 1 VIT family DUF4202 PF13875.6 KUM61600.1 - 2.6e-79 265.5 0.4 2.9e-79 265.3 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) PilM_2 PF11104.8 KUM61600.1 - 0.082 11.9 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; PAM2 PF07145.15 KUM61600.1 - 0.14 11.9 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Ataxin-2 C-terminal region MFS_1 PF07690.16 KUM61601.1 - 2.8e-25 89.0 69.1 3.5e-21 75.5 42.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2304 PF10066.9 KUM61601.1 - 0.076 13.2 0.5 0.076 13.2 0.5 4.1 3 2 2 5 5 5 0 Uncharacterized conserved protein (DUF2304) Condensation PF00668.20 KUM61602.1 - 5e-20 71.6 0.0 7.5e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Condensation domain p450 PF00067.22 KUM61603.1 - 2.4e-49 168.4 0.0 3e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABM PF03992.16 KUM61604.1 - 1.9e-09 37.5 0.0 2.4e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase NIPSNAP PF07978.13 KUM61604.1 - 0.0032 17.7 0.0 0.0039 17.4 0.0 1.1 1 0 0 1 1 1 1 NIPSNAP Rox3 PF08633.10 KUM61606.1 - 1.6e-65 221.2 0.6 1.6e-65 221.2 0.6 1.8 2 1 0 2 2 2 1 Rox3 mediator complex subunit Hamartin PF04388.12 KUM61606.1 - 4.4 5.8 14.5 5.1 5.6 14.5 1.2 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 KUM61606.1 - 4.5 7.1 20.5 2.1 8.2 16.5 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1751 PF08551.10 KUM61607.1 - 0.077 13.6 0.4 0.16 12.6 0.2 1.6 1 1 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) ING PF12998.7 KUM61608.1 - 3.5e-12 46.8 0.0 8.9e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KUM61608.1 - 2.4e-06 27.3 7.6 4e-06 26.6 7.6 1.4 1 0 0 1 1 1 1 PHD-finger DUF4378 PF14309.6 KUM61608.1 - 0.031 14.6 0.1 0.069 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) zf-HC5HC2H PF13771.6 KUM61608.1 - 0.073 13.3 0.9 0.16 12.2 0.9 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KUM61608.1 - 0.31 10.6 2.8 0.58 9.8 2.8 1.4 1 0 0 1 1 1 0 PHD-finger Prp19 PF08606.11 KUM61608.1 - 4 7.5 6.7 10 6.2 2.4 2.5 2 0 0 2 2 2 0 Prp19/Pso4-like BSD PF03909.17 KUM61609.1 - 1.2e-26 92.4 7.7 2.9e-13 49.6 1.0 2.9 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 KUM61609.1 - 3.2e-24 85.1 0.0 8.3e-24 83.7 0.0 1.8 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain PIN_8 PF18476.1 KUM61609.1 - 0.017 15.0 0.4 0.049 13.5 0.4 1.8 1 0 0 1 1 1 0 PIN like domain Nup54 PF13874.6 KUM61609.1 - 0.94 9.6 5.2 1.5 8.9 2.3 2.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Myb_DNA-bind_6 PF13921.6 KUM61610.1 - 0.0012 19.0 0.0 0.0021 18.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KUM61610.1 - 0.0034 17.5 0.3 0.0062 16.7 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain ORC6 PF05460.13 KUM61610.1 - 0.049 12.9 7.8 0.075 12.3 7.8 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Adap_comp_sub PF00928.21 KUM61611.1 - 1.2e-83 280.6 0.0 1.4e-83 280.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KUM61611.1 - 2.6e-05 24.2 0.0 4.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KUM61611.1 - 0.0028 17.1 0.2 0.0055 16.2 0.2 1.5 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain SSB PF00436.25 KUM61612.1 - 1.4e-18 66.9 0.0 1.7e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.15 KUM61613.1 - 2.4e-92 309.2 21.9 3e-92 308.9 21.9 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF3671 PF12420.8 KUM61613.1 - 0.029 14.4 2.4 0.11 12.6 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function Erf4 PF10256.9 KUM61614.1 - 1.8e-39 134.4 0.0 2.3e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4203 PF13886.6 KUM61615.1 - 1.7e-51 174.8 26.8 2.8e-51 174.1 26.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Mucin PF01456.17 KUM61615.1 - 0.0046 17.0 31.3 0.0046 17.0 31.3 4.4 5 1 0 5 5 5 2 Mucin-like glycoprotein Pkinase PF00069.25 KUM61616.1 - 8.1e-21 74.6 0.0 2.1e-09 37.1 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KUM61616.1 - 1.2e-07 31.3 0.0 0.03 13.6 0.0 3.4 4 0 0 4 4 4 2 Protein tyrosine kinase Kdo PF06293.14 KUM61616.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PRD_Mga PF08270.11 KUM61616.1 - 0.22 11.2 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain CN_hydrolase PF00795.22 KUM61617.1 - 1.9e-13 50.4 0.0 5.3e-13 48.9 0.0 1.7 1 1 1 2 2 2 1 Carbon-nitrogen hydrolase HLH PF00010.26 KUM61618.1 - 3.4e-13 49.3 2.8 7.2e-13 48.3 2.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Inhibitor_I9 PF05922.16 KUM61619.1 - 3.5e-11 43.6 0.1 5.1e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 DAHP_snth_FXD PF18152.1 KUM61619.1 - 0.0023 17.7 0.0 0.005 16.6 0.0 1.8 1 1 0 1 1 1 1 DAHP synthase ferredoxin-like domain DPBB_1 PF03330.18 KUM61620.1 - 6.7e-08 32.7 0.1 3.7e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 KUM61620.1 - 0.00026 20.9 0.4 0.00073 19.5 0.4 1.8 1 0 0 1 1 1 1 Pollen allergen Macoilin PF09726.9 KUM61620.1 - 0.65 8.5 5.8 0.85 8.1 5.8 1.1 1 0 0 1 1 1 0 Macoilin family Sec8_exocyst PF04048.14 KUM61621.1 - 2.7e-44 150.5 1.2 6.8e-44 149.2 1.2 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KUM61621.1 - 6.5e-09 35.5 0.2 1.2e-08 34.6 0.2 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KUM61621.1 - 0.00066 18.4 0.3 0.0011 17.6 0.3 1.2 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Dor1 PF04124.12 KUM61621.1 - 0.029 13.0 2.0 0.052 12.2 2.0 1.3 1 0 0 1 1 1 0 Dor1-like family STI1 PF17830.1 KUM61621.1 - 0.16 11.9 0.5 2.5 8.1 0.0 3.0 3 0 0 3 3 3 0 STI1 domain Creatinase_N_2 PF16189.5 KUM61622.1 - 8.1e-52 175.6 0.0 1.3e-51 174.9 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KUM61622.1 - 2.3e-40 138.5 0.0 3.4e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KUM61622.1 - 1.1e-21 76.7 0.1 3e-21 75.2 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KUM61622.1 - 8.1e-12 45.9 0.0 2.3e-10 41.2 0.0 2.8 2 1 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Metallophos PF00149.28 KUM61624.1 - 1e-11 45.7 0.7 2.3e-11 44.6 0.7 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KUM61624.1 - 5.6e-07 29.9 0.1 7.7e-06 26.2 0.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ank_4 PF13637.6 KUM61625.1 - 3.2e-14 53.1 0.1 0.016 15.8 0.0 6.7 6 2 1 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM61625.1 - 3.1e-13 48.6 4.7 0.0019 18.5 0.0 7.4 8 0 0 8 8 8 3 Ankyrin repeat Ank_2 PF12796.7 KUM61625.1 - 7.7e-12 45.6 0.0 0.0025 18.4 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 KUM61625.1 - 3.8e-10 39.7 1.0 0.097 13.2 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KUM61625.1 - 2.1e-07 31.1 2.2 0.016 15.5 0.0 6.0 5 3 1 6 6 6 2 Ankyrin repeats (many copies) ABC_membrane PF00664.23 KUM61626.1 - 7.8e-80 268.4 28.9 8.2e-45 153.6 11.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KUM61626.1 - 5.1e-52 176.0 0.0 6.1e-30 104.5 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KUM61626.1 - 3.6e-10 39.6 2.2 0.0064 15.9 0.1 4.0 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KUM61626.1 - 2.7e-06 27.5 0.6 0.083 13.0 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KUM61626.1 - 6.7e-05 23.3 0.7 0.47 10.8 0.4 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KUM61626.1 - 9.6e-05 22.3 0.5 0.022 14.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KUM61626.1 - 0.00017 21.2 0.5 0.41 10.4 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KUM61626.1 - 0.00076 20.0 0.1 0.094 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KUM61626.1 - 0.0016 18.3 0.1 0.5 10.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 KUM61626.1 - 0.0045 17.1 0.7 0.48 10.5 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 KUM61626.1 - 0.0088 16.3 1.8 1.5 9.1 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KUM61626.1 - 0.011 15.4 1.5 0.3 10.8 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KUM61626.1 - 0.017 14.9 0.3 0.66 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 KUM61626.1 - 0.036 14.3 2.2 9.7 6.4 0.0 3.7 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KUM61626.1 - 0.055 13.5 4.7 2.5 8.1 0.1 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_25 PF13481.6 KUM61626.1 - 0.11 12.1 0.1 5.2 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KUM61626.1 - 1.2 9.0 6.1 0.45 10.4 0.1 2.8 3 0 0 3 3 3 0 NACHT domain bVLRF1 PF18826.1 KUM61627.1 - 2.8e-62 209.0 0.6 4.9e-62 208.2 0.6 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 KUM61627.1 - 7.7e-06 26.1 0.0 1.7e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KUM61627.1 - 0.004 17.5 1.0 0.01 16.2 0.6 2.0 2 0 0 2 2 2 1 Ankyrin repeat zf-C2H2_2 PF12756.7 KUM61627.1 - 0.12 12.7 0.1 0.24 11.8 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RPA43_OB PF17875.1 KUM61627.1 - 0.88 10.2 4.8 2.3 8.8 2.2 2.8 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I SAC3_GANP PF03399.16 KUM61630.1 - 9.6e-103 343.6 2.8 1.4e-102 343.1 2.8 1.2 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KUM61630.1 - 1.6e-05 24.9 0.0 5.2e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DUF2841 PF11001.8 KUM61632.1 - 1.1e-44 151.5 0.0 1.9e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Acyl-CoA_dh_M PF02770.19 KUM61633.1 - 0.0017 18.5 0.0 0.0029 17.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DIOX_N PF14226.6 KUM61634.1 - 3.2e-19 69.8 0.0 1.4e-18 67.8 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KUM61634.1 - 7.7e-14 52.0 0.0 1.3e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KUM61635.1 - 1.6e-30 106.2 17.7 1.6e-30 106.2 17.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TPR_1 PF00515.28 KUM61636.1 - 4.1e-07 29.5 9.0 3.7e-06 26.5 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KUM61636.1 - 5e-07 29.3 5.1 0.0037 17.2 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KUM61636.1 - 2.5e-06 27.1 9.6 0.0012 18.5 0.2 4.4 5 0 0 5 5 5 2 TPR repeat TPR_2 PF07719.17 KUM61636.1 - 1.7e-05 24.6 18.8 0.00011 22.0 0.1 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KUM61636.1 - 0.0013 19.0 15.0 0.87 9.9 1.2 4.8 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KUM61636.1 - 0.037 14.2 4.9 1 9.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KUM61636.1 - 0.063 13.8 6.7 0.39 11.3 0.4 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KUM61636.1 - 0.21 12.5 11.1 12 7.1 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat CDC45 PF02724.14 KUM61637.1 - 2 6.6 7.0 2.6 6.2 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein GMC_oxred_N PF00732.19 KUM61638.1 - 2e-30 106.2 0.0 1.3e-18 67.4 0.0 3.1 2 1 0 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM61638.1 - 1.3e-28 100.3 0.0 2.3e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KUM61638.1 - 0.00021 21.4 0.0 0.00053 20.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM61638.1 - 0.0006 19.1 0.0 0.0013 18.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM61638.1 - 0.0023 17.1 1.0 0.013 14.6 1.2 1.9 2 0 0 2 2 2 1 FAD binding domain HHH PF00633.23 KUM61638.1 - 0.018 14.9 0.3 4.9 7.2 0.0 2.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Pyr_redox_3 PF13738.6 KUM61638.1 - 0.043 13.1 0.0 6.7 5.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM61638.1 - 0.064 12.8 2.0 1.2 8.6 2.5 2.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KUM61638.1 - 0.12 11.4 0.4 0.19 10.7 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 KUM61638.1 - 0.24 11.0 0.7 0.47 10.1 0.7 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Peroxidase_2 PF01328.17 KUM61639.1 - 5e-46 157.6 0.0 8.1e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 DUF1302 PF06980.11 KUM61639.1 - 0.039 12.6 0.0 0.05 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) Beta-lactamase PF00144.24 KUM61640.1 - 7.9e-31 107.5 0.0 1.3e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_98C PF08307.11 KUM61640.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 C-terminal domain Zn_clus PF00172.18 KUM61641.1 - 3.9e-06 26.9 11.0 1.4e-05 25.1 11.0 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4964 PF16334.5 KUM61641.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) Rhodanese PF00581.20 KUM61642.1 - 1.9e-28 99.1 0.0 3.7e-07 30.6 0.0 4.3 4 0 0 4 4 4 4 Rhodanese-like domain IMPDH PF00478.25 KUM61643.1 - 5.1e-126 420.3 4.1 6e-126 420.1 4.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KUM61643.1 - 7e-18 64.8 0.0 3.4e-09 37.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 KUM61643.1 - 1e-08 35.0 9.7 0.0012 18.3 1.1 3.3 2 2 1 3 3 3 3 Nitronate monooxygenase FMN_dh PF01070.18 KUM61643.1 - 3.6e-07 29.5 1.2 6.8e-07 28.6 1.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KUM61643.1 - 0.00017 21.2 3.2 0.0017 17.8 3.1 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.19 KUM61643.1 - 0.018 14.4 1.8 0.065 12.7 1.6 2.0 1 1 1 2 2 2 0 KDPG and KHG aldolase ThiG PF05690.14 KUM61643.1 - 0.035 13.4 2.5 0.052 12.9 0.5 2.1 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG EAL PF00563.20 KUM61643.1 - 0.048 13.2 0.9 17 4.8 0.0 2.9 2 1 1 3 3 3 0 EAL domain FAD_binding_3 PF01494.19 KUM61644.1 - 7.6e-19 68.2 0.2 9e-19 67.9 0.2 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KUM61644.1 - 2.4e-08 33.6 0.6 9.1e-06 25.1 0.2 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KUM61644.1 - 4.8e-08 32.7 0.4 0.0012 18.2 0.0 2.2 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KUM61644.1 - 1e-07 31.4 1.4 0.00061 18.9 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KUM61644.1 - 6e-07 29.0 0.2 0.00026 20.3 0.0 2.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM61644.1 - 3.5e-06 27.1 0.6 2e-05 24.7 0.3 2.2 1 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KUM61644.1 - 1.3e-05 25.6 0.3 0.0015 19.0 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KUM61644.1 - 5.8e-05 22.3 0.2 9.4e-05 21.7 0.2 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KUM61644.1 - 7.6e-05 22.4 1.7 0.00017 21.3 1.4 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KUM61644.1 - 0.0001 21.2 0.4 0.0035 16.1 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KUM61644.1 - 0.00019 20.6 2.3 0.00025 20.3 0.9 1.7 1 1 1 2 2 2 1 FAD binding domain Thi4 PF01946.17 KUM61644.1 - 0.00039 19.7 0.5 0.00081 18.7 0.1 1.6 2 1 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 KUM61644.1 - 0.00044 19.2 0.6 0.00092 18.2 0.1 1.7 1 1 1 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 KUM61644.1 - 0.00074 19.0 0.8 0.004 16.6 0.8 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KUM61644.1 - 0.0047 17.4 0.0 0.011 16.2 0.0 1.8 1 1 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KUM61644.1 - 0.012 14.9 0.2 0.02 14.2 0.2 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KUM61644.1 - 0.025 14.8 0.1 0.055 13.7 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 KUM61644.1 - 0.043 13.8 0.4 10 6.1 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF1382 PF07131.11 KUM61644.1 - 0.2 11.6 0.5 0.45 10.6 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) MFS_1 PF07690.16 KUM61646.1 - 7.2e-28 97.5 22.8 7.2e-28 97.5 22.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM61646.1 - 1.5e-07 30.7 2.5 1.5e-07 30.7 2.5 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KUM61646.1 - 0.0025 16.3 0.6 0.0043 15.5 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM61647.1 - 4.3e-98 329.1 21.7 5.1e-98 328.9 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM61647.1 - 5.4e-30 104.5 42.1 2.8e-25 89.0 22.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SfLAP PF11139.8 KUM61647.1 - 0.065 12.7 8.3 0.6 9.5 0.2 3.1 2 2 0 2 2 2 0 Sap, sulfolipid-1-addressing protein TxDE PF18711.1 KUM61648.1 - 0.0028 17.7 0.1 1.2 9.3 0.0 2.9 1 1 2 3 3 3 2 Toxoflavin-degrading enzyme Sugar_tr PF00083.24 KUM61649.1 - 2.8e-87 293.5 26.8 3.3e-87 293.2 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM61649.1 - 2.8e-20 72.5 27.8 2.8e-20 72.5 27.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-amylase PF00128.24 KUM61650.1 - 1.2e-115 386.7 0.7 9.5e-114 380.4 0.2 2.0 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KUM61650.1 - 2.2e-08 34.1 0.0 5.6e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain MAM33 PF02330.16 KUM61650.1 - 0.018 15.0 0.1 0.051 13.5 0.1 1.7 2 0 0 2 2 2 0 Mitochondrial glycoprotein hDGE_amylase PF14701.6 KUM61650.1 - 0.041 13.0 0.0 0.078 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 KUM61650.1 - 0.051 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Cyc-maltodext_C PF10438.9 KUM61650.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain Alpha-amylase_C PF02806.18 KUM61650.1 - 0.071 13.6 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain Zn_clus PF00172.18 KUM61651.1 - 1.5e-07 31.4 10.1 2.6e-07 30.6 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM61651.1 - 0.00012 21.2 3.4 0.00022 20.4 0.7 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Hep_59 PF07052.11 KUM61652.1 - 1.2e-17 64.6 0.0 1.2e-17 64.6 0.0 2.5 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Actin PF00022.19 KUM61653.1 - 2.8e-147 490.6 0.0 3.2e-147 490.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KUM61653.1 - 0.0057 15.5 0.0 1.3 7.7 0.0 2.9 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 KUM61653.1 - 0.03 14.7 0.0 0.097 13.1 0.1 1.9 2 1 0 2 2 2 0 Cell division protein FtsA Arf PF00025.21 KUM61654.1 - 2.2e-43 147.7 0.0 2.6e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KUM61654.1 - 4.3e-19 68.7 0.0 4.9e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM61654.1 - 4.1e-15 56.0 0.0 6e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KUM61654.1 - 7.6e-08 32.4 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KUM61654.1 - 7.8e-07 28.7 0.0 9.5e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KUM61654.1 - 9.4e-06 25.2 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KUM61654.1 - 0.00018 20.8 0.1 0.00096 18.4 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 KUM61654.1 - 0.0048 16.9 0.1 0.0079 16.2 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 KUM61654.1 - 0.011 15.8 0.1 0.073 13.1 0.1 2.0 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.18 KUM61654.1 - 0.057 13.0 0.2 0.19 11.2 0.0 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B DUF1979 PF09322.10 KUM61654.1 - 0.057 13.3 0.4 3.2 7.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) RsgA_GTPase PF03193.16 KUM61654.1 - 0.14 12.1 0.1 12 5.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase RNA_pol_Rpb2_6 PF00562.28 KUM61655.1 - 5.7e-116 387.8 0.4 7.7e-116 387.4 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KUM61655.1 - 2e-36 125.4 0.0 3.3e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KUM61655.1 - 3.2e-27 94.5 0.0 7.8e-27 93.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 KUM61655.1 - 1.9e-26 91.8 0.0 4.4e-26 90.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 KUM61655.1 - 1.3e-24 86.9 0.0 2.7e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KUM61655.1 - 4.9e-15 55.7 0.0 4.4e-14 52.6 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 Proteasome PF00227.26 KUM61656.1 - 4.8e-10 39.2 0.1 4.6e-08 32.8 0.1 2.1 1 1 0 1 1 1 1 Proteasome subunit Proteasome PF00227.26 KUM61657.1 - 1.1e-19 70.7 0.0 1.2e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Pil1 PF13805.6 KUM61659.1 - 4.3e-99 331.3 6.8 5.6e-99 330.9 6.8 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 BAR_3 PF16746.5 KUM61659.1 - 0.081 12.6 2.7 0.087 12.5 1.0 1.9 2 1 0 2 2 2 0 BAR domain of APPL family APG6_N PF17675.1 KUM61659.1 - 0.34 11.4 8.3 4.3 7.9 6.1 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region CCDC-167 PF15188.6 KUM61659.1 - 4.9 7.6 6.9 1.3 9.5 1.3 2.6 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DivIC PF04977.15 KUM61659.1 - 5.6 6.8 9.9 0.75 9.6 0.7 2.9 1 1 1 2 2 2 0 Septum formation initiator SWI-SNF_Ssr4 PF08549.10 KUM61660.1 - 1.8e-219 731.1 23.4 2.1e-204 681.2 4.1 2.9 1 1 2 3 3 3 3 Fungal domain of unknown function (DUF1750) Zn_clus PF00172.18 KUM61661.1 - 2.2e-10 40.5 11.6 4.5e-10 39.5 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4413 PF14372.6 KUM61661.1 - 0.082 13.3 1.7 0.21 12.0 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) TSC22 PF01166.18 KUM61662.1 - 0.083 13.2 3.5 0.68 10.3 0.4 3.1 2 0 0 2 2 2 0 TSC-22/dip/bun family FlaC_arch PF05377.11 KUM61662.1 - 0.24 11.8 6.6 0.42 11.0 0.8 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) WXG100 PF06013.12 KUM61662.1 - 0.42 10.9 6.2 1.8 8.9 6.2 2.2 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Dicty_CAD PF05720.12 KUM61662.1 - 1.1 9.3 11.7 1.8 8.6 0.2 5.0 4 0 0 4 4 4 0 Cell-cell adhesion domain Abhydrolase_3 PF07859.13 KUM61663.1 - 2.7e-43 148.3 0.0 3.5e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KUM61663.1 - 0.0054 15.7 0.0 0.0077 15.1 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 KUM61663.1 - 0.084 12.1 0.0 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF4723 PF15851.5 KUM61664.1 - 0.011 15.9 0.2 59 3.9 0.0 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4723) Papilin_u7 PF16626.5 KUM61664.1 - 0.12 13.0 4.6 0.64 10.6 1.8 2.3 1 1 1 2 2 2 0 Linking region between Kunitz_BPTI and I-set on papilin HA2 PF04408.23 KUM61665.1 - 3.2e-16 59.6 0.0 8.7e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KUM61665.1 - 3e-15 56.5 0.3 5.5e-14 52.5 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KUM61665.1 - 1.5e-10 41.1 0.0 3.1e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KUM61665.1 - 5.6e-06 26.7 0.4 4.8e-05 23.7 0.0 2.7 2 1 1 3 3 3 1 AAA domain DUF3602 PF12223.8 KUM61665.1 - 0.11 13.1 1.5 0.3 11.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) Gcn1_N PF12074.8 KUM61667.1 - 7.4e-120 400.5 2.6 5.1e-119 397.7 0.5 3.0 2 0 0 2 2 2 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Ribosomal_L19e PF01280.20 KUM61667.1 - 5.9e-60 201.5 7.7 1.6e-59 200.1 7.7 1.8 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT PF02985.22 KUM61667.1 - 1.4e-27 93.3 31.6 0.84 10.1 0.1 21.3 24 0 0 24 24 22 6 HEAT repeat HEAT_2 PF13646.6 KUM61667.1 - 9.9e-21 73.9 42.3 2.5e-05 24.6 3.3 13.4 8 2 5 14 14 14 7 HEAT repeats HEAT_EZ PF13513.6 KUM61667.1 - 2.1e-19 69.6 56.6 3.9e-05 24.1 0.1 20.7 20 4 4 24 24 22 5 HEAT-like repeat Cnd1 PF12717.7 KUM61667.1 - 7.9e-15 55.3 5.9 0.045 13.8 0.2 9.1 8 1 1 9 9 8 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KUM61667.1 - 3.7e-10 40.3 0.0 5.4 7.7 0.1 8.0 6 2 3 9 9 9 2 Vacuolar 14 Fab1-binding region ParcG PF10274.9 KUM61667.1 - 4.1e-09 36.8 2.6 0.043 13.9 0.0 6.3 7 1 0 7 7 5 2 Parkin co-regulated protein TIP120 PF08623.10 KUM61667.1 - 2.6e-06 27.3 0.2 0.0052 16.6 0.0 5.2 5 1 1 6 6 6 1 TATA-binding protein interacting (TIP20) CLASP_N PF12348.8 KUM61667.1 - 3e-06 27.0 0.0 0.19 11.3 0.0 5.7 4 1 1 5 5 5 1 CLASP N terminal IFRD PF05004.13 KUM61667.1 - 4.2e-06 26.1 12.5 0.033 13.3 1.0 5.4 5 0 0 5 5 5 3 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 KUM61667.1 - 0.0004 19.1 10.6 1.3 7.5 0.9 6.5 5 3 1 6 6 6 1 Adaptin N terminal region Tti2 PF10521.9 KUM61667.1 - 0.0023 17.5 0.6 2.1 7.8 0.0 5.3 5 0 0 5 5 5 1 Tti2 family MMS19_C PF12460.8 KUM61667.1 - 0.0068 15.6 22.6 0.65 9.0 1.0 7.3 8 0 0 8 8 8 2 RNAPII transcription regulator C-terminal FANCI_S2 PF14676.6 KUM61667.1 - 0.033 14.5 1.4 0.49 10.7 0.0 3.7 4 0 0 4 4 2 0 FANCI solenoid 2 TFCD_C PF12612.8 KUM61667.1 - 0.24 11.2 3.1 3.9 7.3 0.0 4.5 4 0 0 4 4 4 0 Tubulin folding cofactor D C terminal Dopey_N PF04118.14 KUM61667.1 - 0.36 9.9 1.6 73 2.3 0.0 5.2 6 2 2 8 8 8 0 Dopey, N-terminal DUF937 PF06078.11 KUM61667.1 - 3.9 8.1 14.4 18 5.9 0.0 6.6 7 1 0 7 7 6 0 Bacterial protein of unknown function (DUF937) TIP39 PF14980.6 KUM61668.1 - 0.2 11.6 1.5 0.54 10.2 0.2 2.3 2 0 0 2 2 2 0 TIP39 peptide Kelch_6 PF13964.6 KUM61670.1 - 0.00017 21.8 1.0 0.043 14.1 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 KUM61670.1 - 0.0027 17.7 4.4 0.024 14.7 0.1 4.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.6 KUM61670.1 - 0.0029 17.9 13.1 0.0054 17.0 0.1 5.1 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 KUM61670.1 - 0.019 14.6 0.2 0.5 10.0 0.0 2.8 2 0 0 2 2 2 0 Kelch motif TMEM154 PF15102.6 KUM61670.1 - 0.028 14.3 0.2 0.089 12.7 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family Mid2 PF04478.12 KUM61670.1 - 0.087 12.7 0.9 0.24 11.3 0.9 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SNF2_N PF00176.23 KUM61672.1 - 9.8e-57 192.2 0.0 1.5e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KUM61672.1 - 1.2e-24 85.9 1.9 8.1e-17 60.9 0.1 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 KUM61672.1 - 4.4e-21 75.1 1.2 9.2e-21 74.1 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KUM61672.1 - 1.2e-18 67.5 0.0 3.1e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cdh1_DBD_1 PF18196.1 KUM61672.1 - 7.5e-06 26.3 0.8 0.00011 22.6 0.1 4.6 4 1 1 5 5 5 2 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 KUM61672.1 - 3.7e-05 23.8 0.1 0.00078 19.5 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 KUM61672.1 - 0.028 14.6 1.2 0.066 13.4 0.0 2.2 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain ABC_tran PF00005.27 KUM61674.1 - 6.6e-35 120.6 0.0 1.7e-16 61.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 KUM61674.1 - 3e-14 52.5 5.4 3e-14 52.5 5.4 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 KUM61674.1 - 7.1e-11 42.0 1.8 0.0027 17.2 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KUM61674.1 - 1.4e-09 38.2 3.9 0.17 11.6 1.3 4.2 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KUM61674.1 - 6.9e-06 26.5 0.1 0.0082 16.6 0.1 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KUM61674.1 - 7.9e-06 26.3 0.0 0.024 15.0 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KUM61674.1 - 2.2e-05 24.4 0.1 0.23 11.1 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain Rad17 PF03215.15 KUM61674.1 - 4.3e-05 23.5 0.1 0.018 14.9 0.0 2.8 2 1 1 3 3 3 1 Rad17 P-loop domain Fer4 PF00037.27 KUM61674.1 - 7.3e-05 22.4 2.5 7.3e-05 22.4 2.5 2.8 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_22 PF13401.6 KUM61674.1 - 8.4e-05 22.9 0.0 0.021 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KUM61674.1 - 0.00012 22.1 0.0 0.45 10.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 KUM61674.1 - 0.00039 20.6 0.0 0.064 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KUM61674.1 - 0.00046 19.9 0.2 0.59 9.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 KUM61674.1 - 0.0008 19.8 0.9 0.27 11.6 0.0 2.9 3 0 0 3 3 2 1 RNA helicase Fer4_21 PF14697.6 KUM61674.1 - 0.00086 19.4 11.5 0.0015 18.6 11.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_18 PF13238.6 KUM61674.1 - 0.0016 19.0 0.0 2.1 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KUM61674.1 - 0.0019 17.9 2.1 0.12 12.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KUM61674.1 - 0.0021 18.1 0.1 0.027 14.5 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KUM61674.1 - 0.0023 17.9 1.7 0.17 11.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Fer4_6 PF12837.7 KUM61674.1 - 0.0023 17.9 12.2 0.0077 16.3 2.2 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_7 PF12775.7 KUM61674.1 - 0.0031 17.1 0.5 0.053 13.0 0.2 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 KUM61674.1 - 0.0042 17.6 0.9 0.36 11.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KUM61674.1 - 0.0056 16.4 0.3 1.4 8.6 0.0 2.7 3 0 0 3 3 2 1 Thymidylate kinase Fer4_10 PF13237.6 KUM61674.1 - 0.0067 16.5 15.5 0.021 14.9 1.6 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain SRP54 PF00448.22 KUM61674.1 - 0.0076 15.9 3.6 0.11 12.1 0.2 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KUM61674.1 - 0.019 14.7 0.8 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KUM61674.1 - 0.025 14.6 0.2 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KUM61674.1 - 0.027 13.7 0.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_13 PF13166.6 KUM61674.1 - 0.028 13.1 0.0 0.06 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KUM61674.1 - 0.032 14.5 0.1 5.4 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KUM61674.1 - 0.038 13.1 0.1 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Fer4_9 PF13187.6 KUM61674.1 - 0.055 13.6 11.5 0.11 12.7 11.5 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain VirE PF05272.11 KUM61674.1 - 0.065 12.9 0.1 7.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E SbcCD_C PF13558.6 KUM61674.1 - 0.078 13.2 0.0 12 6.2 0.0 2.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_16 PF13484.6 KUM61674.1 - 0.078 13.9 0.3 0.078 13.9 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_14 PF13173.6 KUM61674.1 - 0.097 12.7 0.1 8.3 6.5 0.1 2.9 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KUM61674.1 - 0.11 12.4 2.8 1.4 8.8 0.1 2.7 3 0 0 3 3 2 0 NTPase Fer4_17 PF13534.6 KUM61674.1 - 0.12 13.0 0.2 0.12 13.0 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain ATPase PF06745.13 KUM61674.1 - 0.18 11.1 0.1 0.39 10.0 0.1 1.5 1 0 0 1 1 1 0 KaiC MukB PF04310.12 KUM61674.1 - 0.22 11.3 0.5 25 4.6 0.1 2.6 3 0 0 3 3 2 0 MukB N-terminal MeaB PF03308.16 KUM61674.1 - 0.22 10.5 0.3 0.96 8.4 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KUM61674.1 - 0.22 11.6 0.4 34 4.5 0.4 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Fer4_8 PF13183.6 KUM61674.1 - 0.26 11.7 6.6 0.29 11.6 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain PduV-EutP PF10662.9 KUM61674.1 - 0.4 10.4 3.0 0.35 10.6 0.1 2.3 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_7 PF12838.7 KUM61674.1 - 0.5 11.0 12.6 0.072 13.7 1.6 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KUM61674.1 - 1.4 9.2 9.5 0.25 11.5 1.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Aminotran_3 PF00202.21 KUM61676.1 - 1.2e-17 63.7 0.0 1.5e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Archaeal_AmoA PF12942.7 KUM61676.1 - 0.12 12.1 0.1 3.2 7.4 0.0 2.0 1 1 1 2 2 2 0 Archaeal ammonia monooxygenase subunit A (AmoA) Nop PF01798.18 KUM61678.1 - 2e-60 204.1 0.1 2.7e-60 203.7 0.1 1.1 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KUM61678.1 - 4.8e-46 156.6 0.5 1.5e-45 155.0 0.5 1.9 1 1 0 1 1 1 1 Prp31 C terminal domain HAT PF02184.16 KUM61679.1 - 7.4e-20 70.6 74.9 3.3e-15 55.7 3.7 12.6 14 0 0 14 14 14 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KUM61679.1 - 1.1e-17 63.2 23.5 0.00012 22.6 0.2 10.4 7 3 5 12 12 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 KUM61679.1 - 2.6e-14 53.5 7.4 2.3e-06 28.0 0.0 6.2 8 0 0 8 8 6 3 Tetratricopeptide repeat Suf PF05843.14 KUM61679.1 - 4.5e-12 46.6 24.0 0.00055 20.0 0.2 6.5 2 2 3 5 5 5 3 Suppressor of forked protein (Suf) TPR_17 PF13431.6 KUM61679.1 - 5.1e-12 45.3 1.3 0.36 11.3 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KUM61679.1 - 1.4e-07 31.1 4.0 16 6.0 0.0 7.4 6 0 0 6 6 6 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KUM61679.1 - 2.7e-07 30.1 20.2 0.00018 20.8 4.6 4.5 4 2 0 4 4 4 3 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 KUM61679.1 - 3.8e-07 29.7 10.2 0.18 12.0 0.0 7.2 7 0 0 7 7 6 1 Tetratricopeptide repeat RAB3GAP2_C PF14656.6 KUM61679.1 - 0.0011 17.4 1.7 0.0017 16.7 0.1 1.9 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit C-terminus TPR_16 PF13432.6 KUM61679.1 - 0.002 18.7 6.1 4.4 8.0 0.0 5.1 6 1 1 7 7 5 1 Tetratricopeptide repeat Rox3 PF08633.10 KUM61679.1 - 0.0031 17.8 2.0 0.0064 16.8 2.0 1.5 1 0 0 1 1 1 1 Rox3 mediator complex subunit TPR_15 PF13429.6 KUM61679.1 - 0.029 13.6 17.9 0.84 8.8 0.3 5.8 2 2 3 6 6 6 0 Tetratricopeptide repeat ER PF01133.17 KUM61679.1 - 0.083 12.9 2.4 4.3 7.4 0.4 3.9 2 2 3 5 5 5 0 Enhancer of rudimentary TPR_1 PF00515.28 KUM61679.1 - 0.13 12.1 7.4 8.6 6.4 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 KUM61679.1 - 0.21 11.7 7.6 11 6.3 0.1 5.1 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KUM61679.1 - 1.2 9.9 19.8 11 6.9 0.0 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 KUM61679.1 - 3.3 8.0 24.4 7 7.0 0.1 7.3 9 1 0 9 9 8 0 Tetratricopeptide repeat Lactamase_B PF00753.27 KUM61680.1 - 8.1e-11 42.3 0.3 1.3e-10 41.7 0.3 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KUM61680.1 - 0.0023 17.5 0.0 0.0054 16.3 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KUM61680.1 - 0.0086 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain zf-C2H2 PF00096.26 KUM61683.1 - 1.4e-07 31.6 11.1 7.7e-06 26.1 2.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KUM61683.1 - 2.1e-05 24.7 2.5 2.1e-05 24.7 2.5 4.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KUM61683.1 - 0.00022 21.8 1.2 0.00022 21.8 1.2 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KUM61683.1 - 0.00071 19.9 0.5 0.00071 19.9 0.5 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KUM61683.1 - 0.00098 19.4 5.8 0.0021 18.3 5.8 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF2225 PF09986.9 KUM61683.1 - 0.0013 18.5 0.3 0.0022 17.8 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.8 KUM61683.1 - 0.0033 17.7 0.5 0.009 16.3 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1178 PF06676.11 KUM61683.1 - 0.0055 17.1 1.0 0.011 16.1 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1178) zf-C2H2_6 PF13912.6 KUM61683.1 - 0.019 15.0 0.4 0.069 13.2 0.4 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KUM61683.1 - 0.042 13.6 0.2 0.042 13.6 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KUM61683.1 - 0.12 12.7 2.3 0.2 12.0 2.3 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KUM61683.1 - 0.16 11.8 2.1 0.26 11.1 2.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 KUM61683.1 - 0.18 11.9 5.2 0.41 10.7 5.2 1.6 1 0 0 1 1 1 0 BED zinc finger UPF0261 PF06792.11 KUM61684.1 - 1.5e-155 518.1 0.3 1.7e-155 517.9 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) FYRC PF05965.14 KUM61684.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 F/Y rich C-terminus AdoHcyase PF05221.17 KUM61685.1 - 1.9e-129 431.1 0.0 1.6e-73 247.4 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KUM61685.1 - 1.2e-80 269.3 2.8 2e-80 268.6 2.8 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KUM61685.1 - 3.1e-06 26.7 0.1 6.7e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KUM61685.1 - 0.0021 17.6 0.3 0.0041 16.7 0.3 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KUM61685.1 - 0.0058 16.9 0.1 0.013 15.8 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Oxidored_nitro PF00148.19 KUM61685.1 - 0.021 13.6 0.1 0.18 10.5 0.0 2.2 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase ELFV_dehydrog PF00208.21 KUM61685.1 - 0.029 14.1 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Urocanase PF01175.18 KUM61685.1 - 0.15 11.7 0.4 0.27 10.9 0.4 1.4 1 0 0 1 1 1 0 Urocanase Rossmann-like domain zf-H2C2_2 PF13465.6 KUM61686.1 - 8.7e-07 29.1 9.9 2.6e-06 27.6 0.9 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KUM61686.1 - 1.3e-05 25.1 1.3 0.021 14.8 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KUM61686.1 - 2.2e-05 24.7 0.8 2.2e-05 24.7 0.8 3.2 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM61686.1 - 0.00042 20.9 9.2 0.0035 18.1 0.5 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger SUIM_assoc PF16619.5 KUM61686.1 - 0.0018 18.3 0.8 0.011 15.8 0.8 2.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 zf-C2H2_jaz PF12171.8 KUM61686.1 - 0.005 17.1 1.0 0.29 11.5 0.3 2.9 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KUM61686.1 - 0.016 15.8 18.9 0.076 13.7 0.0 4.4 4 1 1 5 5 5 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KUM61686.1 - 0.034 13.9 0.9 0.28 11.0 0.0 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Aldo_ket_red PF00248.21 KUM61688.1 - 5.9e-53 180.0 0.0 7.1e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family CRT10 PF08728.10 KUM61688.1 - 0.2 9.8 0.0 0.25 9.5 0.0 1.1 1 0 0 1 1 1 0 CRT10 Hemopexin PF00045.19 KUM61689.1 - 2.2e-14 53.1 4.9 0.00012 21.9 0.1 4.1 4 0 0 4 4 4 3 Hemopexin Ten_N PF06484.12 KUM61690.1 - 0.18 11.6 4.9 0.23 11.3 4.9 1.1 1 0 0 1 1 1 0 Teneurin Intracellular Region PhyH PF05721.13 KUM61691.1 - 3.8e-08 33.9 0.0 1.2e-07 32.2 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_15 PF00723.21 KUM61696.1 - 1.1e-42 146.4 0.0 1.6e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Glyco_hydro_15 PF00723.21 KUM61697.1 - 0.00036 19.5 0.0 0.00036 19.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Cullin PF00888.22 KUM61698.1 - 5e-23 81.6 1.7 7.8e-23 80.9 1.7 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KUM61698.1 - 2.3e-22 79.2 0.1 1.5e-21 76.7 0.0 2.3 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 TauD PF02668.16 KUM61699.1 - 1.4e-31 110.3 0.0 1.8e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.24 KUM61700.1 - 6.1e-121 404.4 14.2 9.6e-121 403.8 14.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM61700.1 - 7.7e-28 97.4 48.7 1.8e-23 83.0 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ni_hydr_CYTB PF01292.20 KUM61700.1 - 1 9.0 15.9 0.54 9.8 5.8 2.7 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Pkr1 PF08636.10 KUM61701.1 - 9.8e-31 105.7 7.0 1.2e-30 105.4 7.0 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Ashwin PF15323.6 KUM61701.1 - 0.019 15.0 0.7 0.023 14.7 0.7 1.1 1 0 0 1 1 1 0 Developmental protein Phage_Gp23 PF10669.9 KUM61701.1 - 0.03 14.6 0.7 0.064 13.6 0.7 1.5 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) FHIPEP PF00771.20 KUM61701.1 - 0.084 11.3 0.0 0.097 11.1 0.0 1.0 1 0 0 1 1 1 0 FHIPEP family GATase PF00117.28 KUM61702.1 - 0.0019 18.0 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ArfGap PF01412.18 KUM61703.1 - 1.7 8.7 5.9 3.3 7.8 5.9 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Peptidase_C15 PF01470.17 KUM61704.1 - 2e-12 47.7 0.0 0.00016 21.9 0.0 2.9 2 1 0 2 2 2 2 Pyroglutamyl peptidase MOSC PF03473.17 KUM61705.1 - 4.4e-28 97.9 0.0 7.6e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KUM61705.1 - 3.1e-21 75.5 0.0 2.7e-20 72.4 0.0 2.1 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain p450 PF00067.22 KUM61707.1 - 7.8e-40 137.0 0.0 9.4e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cob_adeno_trans PF01923.18 KUM61707.1 - 0.078 13.1 0.4 0.37 10.9 0.1 2.2 2 1 0 2 2 2 0 Cobalamin adenosyltransferase Mad3_BUB1_II PF08171.11 KUM61708.1 - 3.1e-09 36.8 0.0 1.4e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 KUM61708.1 - 7.7e-09 35.3 0.0 1.2e-07 31.4 0.1 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM61708.1 - 0.0027 17.0 0.0 0.012 14.9 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM61708.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like AP_endonuc_2 PF01261.24 KUM61710.1 - 2e-28 99.3 0.0 2.7e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.12 KUM61711.1 - 1.1e-44 151.3 0.0 1.5e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 KUM61711.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein TPT PF03151.16 KUM61713.1 - 4.1e-22 78.9 16.2 5.2e-22 78.5 16.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KUM61713.1 - 0.00085 19.5 37.5 0.0022 18.2 14.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KUM61713.1 - 0.022 14.0 18.4 0.035 13.3 18.4 1.2 1 0 0 1 1 1 0 UAA transporter family PBP1_TM PF14812.6 KUM61713.1 - 1.4 9.4 6.5 3.9 7.9 6.5 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Lactonase PF10282.9 KUM61714.1 - 1.1e-82 278.1 0.0 1.3e-82 277.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller He_PIG PF05345.12 KUM61714.1 - 0.0067 16.6 0.3 0.018 15.2 0.3 1.8 1 0 0 1 1 1 1 Putative Ig domain CwfJ_C_1 PF04677.15 KUM61715.1 - 4.6e-24 84.6 0.0 9.5e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KUM61715.1 - 1.2e-14 55.0 0.4 2.3e-14 54.0 0.4 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.12 KUM61716.1 - 6.1e-193 642.5 0.1 6.1e-193 642.5 0.1 5.0 7 1 0 7 7 7 1 Down-regulated in metastasis HEAT PF02985.22 KUM61716.1 - 0.0016 18.5 5.8 0.12 12.7 0.0 6.5 7 0 0 7 7 7 1 HEAT repeat BP28CT PF08146.12 KUM61716.1 - 0.027 14.3 0.1 0.3 10.9 0.0 3.0 2 0 0 2 2 2 0 BP28CT (NUC211) domain MMS19_C PF12460.8 KUM61716.1 - 0.12 11.5 11.1 5.1 6.1 0.4 5.5 5 1 1 6 6 6 0 RNAPII transcription regulator C-terminal Rhodanese PF00581.20 KUM61717.1 - 1.2e-11 45.1 0.0 2.5e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain zf-DNL PF05180.12 KUM61720.1 - 4e-28 97.1 0.4 6.9e-28 96.4 0.4 1.4 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.13 KUM61720.1 - 0.00018 21.1 0.6 0.00035 20.2 0.6 1.4 1 0 0 1 1 1 1 CSL zinc finger TFIIS_C PF01096.18 KUM61720.1 - 0.0011 18.8 3.2 0.055 13.3 0.5 2.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Elf1 PF05129.13 KUM61720.1 - 0.01 15.9 0.2 0.017 15.1 0.2 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 KUM61720.1 - 0.032 14.3 0.7 0.069 13.3 0.7 1.5 1 0 0 1 1 1 0 Zinc ribbon domain HypA PF01155.19 KUM61720.1 - 0.043 13.8 0.6 0.067 13.2 0.6 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TIP41 PF04176.13 KUM61720.1 - 0.053 13.0 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 TIP41-like family DUF2039 PF10217.9 KUM61720.1 - 0.087 13.2 0.8 0.14 12.5 0.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) DNA_RNApol_7kD PF03604.13 KUM61720.1 - 0.12 12.1 1.3 4.6 7.0 0.3 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 KUM61720.1 - 0.14 12.1 0.6 3 7.8 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain E7 PF00527.18 KUM61720.1 - 0.58 10.4 4.5 3.5 7.9 4.5 2.2 1 1 0 1 1 1 0 E7 protein, Early protein Zn_Tnp_IS1595 PF12760.7 KUM61720.1 - 7.3 6.7 7.7 47 4.1 0.8 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Cullin PF00888.22 KUM61721.1 - 1.8e-199 664.4 14.4 1.8e-199 664.4 14.4 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KUM61721.1 - 3.9e-25 87.7 0.8 3.9e-25 87.7 0.8 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain DNA_pol_phi PF04931.13 KUM61722.1 - 7.6e-262 870.9 21.7 9.4e-262 870.6 21.7 1.1 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 KUM61722.1 - 0.011 15.2 25.5 0.03 13.8 25.5 1.7 1 0 0 1 1 1 0 SDA1 DUF1840 PF08895.11 KUM61722.1 - 0.61 10.4 9.2 1.9 8.9 2.5 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) BUD22 PF09073.10 KUM61722.1 - 3.4 6.9 25.8 10 5.4 25.8 1.7 1 0 0 1 1 1 0 BUD22 SLAC1 PF03595.17 KUM61725.1 - 9e-63 212.5 28.0 1e-62 212.3 28.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SQHop_cyclase_N PF13249.6 KUM61726.1 - 1.6e-115 385.2 0.2 3.9e-106 354.4 0.0 4.3 3 2 0 5 5 5 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KUM61726.1 - 3.6e-113 377.9 3.3 1e-107 360.0 0.8 3.1 3 0 0 3 3 3 3 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KUM61726.1 - 4.2e-29 100.0 20.1 2.8e-09 36.5 0.1 7.7 8 0 0 8 8 8 5 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KUM61726.1 - 0.0001 21.4 0.1 2.1 7.3 0.0 4.7 4 1 2 6 6 6 3 A-macroglobulin TED domain Pec_lyase PF09492.10 KUM61726.1 - 0.025 13.9 0.3 44 3.3 0.0 4.1 4 1 0 5 5 5 0 Pectic acid lyase Transferase PF02458.15 KUM61727.1 - 0.006 15.3 0.0 0.0073 15.0 0.0 1.1 1 0 0 1 1 1 1 Transferase family p450 PF00067.22 KUM61729.1 - 8.1e-10 38.0 0.0 1.3e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF5343 PF17278.2 KUM61729.1 - 0.13 12.3 0.1 3.5 7.7 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5343) WD40 PF00400.32 KUM61730.1 - 3.4e-64 211.2 16.2 7.4e-11 42.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM61730.1 - 5e-29 100.4 0.3 7.5e-05 23.0 0.0 6.7 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KUM61730.1 - 8.1e-15 54.6 0.1 0.025 13.6 0.0 6.1 1 1 5 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KUM61730.1 - 2.5e-09 36.8 1.6 0.019 14.9 0.0 5.9 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KUM61730.1 - 0.0001 21.9 1.7 29 4.5 0.0 5.2 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Gmad1 PF10647.9 KUM61730.1 - 0.00012 22.0 1.1 0.14 11.8 0.0 3.5 2 1 2 4 4 4 1 Lipoprotein LpqB beta-propeller domain DUF5570 PF17731.1 KUM61730.1 - 0.00015 21.9 4.3 0.41 10.7 0.1 3.9 1 1 2 4 4 4 2 Family of unknown function (DUF5570) Nup160 PF11715.8 KUM61730.1 - 0.00094 17.9 12.8 0.046 12.4 0.1 4.7 3 1 2 6 6 6 2 Nucleoporin Nup120/160 DUF2415 PF10313.9 KUM61730.1 - 0.0012 18.7 0.5 15 5.6 0.0 5.1 5 0 0 5 5 5 0 Uncharacterised protein domain (DUF2415) DUF3748 PF12566.8 KUM61730.1 - 0.022 14.7 0.7 5.2 7.0 0.0 3.7 3 2 1 5 5 5 0 Protein of unknown function (DUF3748) Nucleoporin_N PF08801.11 KUM61730.1 - 0.032 13.0 0.2 0.76 8.5 0.1 3.2 1 1 1 3 3 3 0 Nup133 N terminal like Stimulus_sens_1 PF13756.6 KUM61730.1 - 0.058 14.0 0.0 58 4.3 0.0 3.8 5 0 0 5 5 5 0 Stimulus-sensing domain Ribosomal_L21e PF01157.18 KUM61730.1 - 0.1 12.4 0.0 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L21e MFS_1 PF07690.16 KUM61731.1 - 5.8e-32 111.0 26.6 5.8e-32 111.0 26.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_2_1 PF04971.12 KUM61731.1 - 0.95 9.5 7.5 0.52 10.4 0.2 2.9 1 1 1 2 2 2 0 Bacteriophage P21 holin S Ank_2 PF12796.7 KUM61732.1 - 1.6e-36 124.7 1.8 1.9e-10 41.2 0.1 5.1 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM61732.1 - 7.2e-31 106.2 5.0 1.6e-07 31.8 0.1 6.5 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM61732.1 - 4e-30 100.5 7.0 0.021 15.3 0.0 9.7 10 1 0 10 10 10 7 Ankyrin repeat Ank PF00023.30 KUM61732.1 - 8.7e-30 101.9 6.7 2.6e-05 24.4 0.3 8.9 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KUM61732.1 - 4.4e-22 77.9 6.2 1.5e-07 31.6 0.2 6.7 4 2 3 7 7 7 6 Ankyrin repeats (many copies) F-box-like PF12937.7 KUM61732.1 - 0.0061 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like Ank_2 PF12796.7 KUM61733.1 - 1.5e-13 51.1 0.0 5.1e-12 46.2 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM61733.1 - 1e-12 48.3 0.1 1.2e-05 25.8 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM61733.1 - 2.1e-12 47.0 0.0 1.2e-05 25.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM61733.1 - 8.3e-09 35.0 0.0 0.016 15.7 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KUM61733.1 - 3.3e-08 33.6 0.5 0.02 15.3 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeat Shikimate_DH PF01488.20 KUM61733.1 - 0.011 15.8 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DASH_Hsk3 PF08227.11 KUM61734.1 - 6e-22 77.7 2.3 8.3e-22 77.3 2.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Big_3_3 PF13750.6 KUM61734.1 - 0.021 14.5 0.5 0.028 14.1 0.5 1.1 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) BBS2_C PF14782.6 KUM61734.1 - 0.1 11.3 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal ApbA PF02558.16 KUM61735.1 - 5.1e-26 91.1 0.0 7.6e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KUM61735.1 - 5.8e-19 68.5 0.0 1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal WH2 PF02205.20 KUM61736.1 - 0.008 16.0 4.5 0.24 11.3 4.5 2.5 1 1 0 1 1 1 1 WH2 motif F-box-like PF12937.7 KUM61737.1 - 8.6e-06 25.6 1.6 1.1e-05 25.2 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KUM61737.1 - 0.00022 21.1 1.0 0.00046 20.0 0.1 2.0 2 0 0 2 2 2 1 F-box F-box PF00646.33 KUM61737.1 - 0.0089 15.9 0.8 0.022 14.7 0.1 2.1 2 0 0 2 2 2 1 F-box domain CorA PF01544.18 KUM61738.1 - 1.4e-07 31.1 0.0 2.3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DDE_Tnp_ISL3 PF01610.17 KUM61738.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Transposase ApoL PF05461.11 KUM61738.1 - 4.8 6.4 8.3 0.055 12.8 0.5 1.7 2 0 0 2 2 2 0 Apolipoprotein L AdoMet_MTase PF07757.13 KUM61739.1 - 1.6e-25 89.6 0.0 3.3e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase His_Phos_1 PF00300.22 KUM61740.1 - 9.1e-37 126.6 0.5 1.4e-20 73.9 0.1 2.3 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF604 PF04646.12 KUM61741.1 - 1.5e-07 31.1 0.0 2.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 KUM61741.1 - 0.00033 20.2 0.0 0.00071 19.1 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Ser_hydrolase PF06821.13 KUM61741.1 - 0.081 12.8 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 Serine hydrolase MFS_1 PF07690.16 KUM61742.1 - 4.4e-41 141.0 23.1 4.4e-41 141.0 23.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM61742.1 - 7e-14 51.5 5.5 7e-14 51.5 5.5 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KUM61742.1 - 0.0023 16.9 8.2 0.081 11.8 2.9 2.7 2 1 1 3 3 3 2 MFS_1 like family OATP PF03137.20 KUM61742.1 - 0.0033 15.8 3.1 0.0095 14.3 2.5 1.9 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Lipase_3 PF01764.25 KUM61743.1 - 8.6e-16 58.1 0.1 8.3e-12 45.2 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) Abhydrolase_6 PF12697.7 KUM61743.1 - 0.019 15.6 4.9 0.056 14.0 4.9 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family zf-C2H2 PF00096.26 KUM61744.1 - 0.00016 22.0 15.6 0.0037 17.6 3.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KUM61744.1 - 0.00069 19.9 1.6 0.00069 19.9 1.6 3.7 4 0 0 4 4 4 1 Zinc-finger double domain Zn-ribbon_8 PF09723.10 KUM61744.1 - 0.59 10.3 2.6 13 6.0 0.5 2.4 2 0 0 2 2 2 0 Zinc ribbon domain SMC_N PF02463.19 KUM61745.1 - 5e-22 78.4 0.0 1.5e-21 76.9 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KUM61745.1 - 1.4e-17 64.9 0.0 1.4e-17 64.9 0.0 4.6 2 2 0 4 4 4 1 AAA domain AAA_15 PF13175.6 KUM61745.1 - 7.6e-06 25.9 18.1 2.8e-05 24.0 0.0 3.7 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KUM61745.1 - 0.00036 20.2 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KUM61745.1 - 0.0074 16.1 7.8 0.033 14.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KUM61745.1 - 0.11 13.0 0.0 0.11 13.0 0.0 4.6 3 2 0 3 3 3 0 ABC transporter BTB PF00651.31 KUM61746.1 - 1e-25 90.1 0.0 2.9e-13 50.0 0.2 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.6 KUM61746.1 - 6.3e-07 29.5 0.2 2.5e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KUM61746.1 - 7.5e-07 29.7 0.0 1.5e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM61746.1 - 2.2e-06 28.1 0.0 5.5e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KUM61746.1 - 0.0002 21.7 0.0 0.018 15.5 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KUM61746.1 - 0.029 14.9 0.1 0.26 12.0 0.1 2.6 2 0 0 2 2 2 0 Ankyrin repeat DUF3342 PF11822.8 KUM61746.1 - 0.031 14.4 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Pkinase PF00069.25 KUM61747.1 - 3.1e-53 180.8 5.5 1.7e-34 119.4 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KUM61747.1 - 3.4e-36 124.9 0.0 9e-26 90.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KUM61747.1 - 0.012 15.0 0.1 0.033 13.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KUM61747.1 - 0.05 13.5 1.5 0.82 9.5 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF3896 PF13035.6 KUM61747.1 - 0.84 9.8 6.1 0.5 10.6 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3896) Wbp11 PF09429.10 KUM61748.1 - 1.4e-20 73.4 13.4 1.4e-20 73.4 13.4 2.2 2 1 0 2 2 2 1 WW domain binding protein 11 PhaP_Bmeg PF09602.10 KUM61749.1 - 0.00066 19.7 0.2 0.001 19.0 0.2 1.2 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF1664 PF07889.12 KUM61749.1 - 0.00066 19.7 2.0 0.0024 17.9 2.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 KUM61749.1 - 0.00098 18.7 0.7 0.0015 18.1 0.7 1.3 1 0 0 1 1 1 1 fzo-like conserved region Fib_alpha PF08702.10 KUM61749.1 - 0.0027 17.9 3.5 0.0061 16.8 3.5 1.5 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family CLZ PF16526.5 KUM61749.1 - 0.005 17.2 0.9 0.86 10.0 0.1 2.4 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 KUM61749.1 - 0.0088 15.4 2.2 0.0095 15.3 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 KUM61749.1 - 0.0099 15.9 1.1 0.093 12.8 0.9 2.1 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus HSCB_C PF07743.13 KUM61749.1 - 0.016 15.7 2.1 0.21 12.1 0.3 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Exonuc_VII_L PF02601.15 KUM61749.1 - 0.02 14.5 2.2 0.022 14.3 2.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cobalamin_bind PF01122.19 KUM61749.1 - 0.04 12.8 0.1 0.056 12.3 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic cobalamin-binding protein NAP PF00956.18 KUM61749.1 - 0.096 11.8 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Prominin PF05478.11 KUM61749.1 - 0.22 9.4 0.7 0.26 9.2 0.7 1.0 1 0 0 1 1 1 0 Prominin CorA PF01544.18 KUM61749.1 - 0.46 9.8 4.5 0.63 9.3 4.5 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Snapin_Pallidin PF14712.6 KUM61749.1 - 9.5 6.7 8.7 2.2 8.8 0.1 2.6 2 1 1 3 3 3 0 Snapin/Pallidin Rpr2 PF04032.16 KUM61750.1 - 1.5e-26 92.5 2.3 2.5e-26 91.8 2.3 1.4 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.6 KUM61750.1 - 0.22 11.5 1.6 1.6 8.7 0.1 2.6 2 0 0 2 2 2 0 Nudix N-terminal HNH_5 PF14279.6 KUM61750.1 - 0.71 9.8 3.8 1.1 9.1 0.1 2.8 3 0 0 3 3 3 0 HNH endonuclease RPN2_C PF18004.1 KUM61750.1 - 0.83 9.6 4.1 0.15 12.0 0.5 1.6 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DEAD PF00270.29 KUM61751.1 - 2.1e-36 125.3 0.2 5e-36 124.1 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM61751.1 - 3.2e-27 95.1 0.1 8.8e-25 87.2 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KUM61751.1 - 1e-08 35.3 0.0 2.5e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MFS_1 PF07690.16 KUM61753.1 - 1.5e-12 47.2 26.1 4.5e-12 45.5 24.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KUM61753.1 - 3e-06 27.0 1.4 3e-06 27.0 1.4 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 KUM61753.1 - 0.00036 19.5 12.0 0.00036 19.5 12.0 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter SDF PF00375.18 KUM61753.1 - 0.019 14.0 0.0 0.038 13.0 0.0 1.5 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family ATP-grasp_4 PF13535.6 KUM61754.1 - 0.017 14.7 0.0 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain Phage_head_fibr PF11133.8 KUM61754.1 - 0.17 11.2 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Head fiber protein Fungal_trans PF04082.18 KUM61755.1 - 1.3e-16 60.5 1.1 7.5e-16 57.9 1.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ribonuc_L-PSP PF01042.21 KUM61756.1 - 6.1e-12 45.6 0.0 7.4e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Gly_transf_sug PF04488.15 KUM61757.1 - 7e-13 49.0 0.0 1.7e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Amidinotransf PF02274.17 KUM61757.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase Transketolase_N PF00456.21 KUM61758.1 - 6.2e-14 51.7 0.8 1.4e-12 47.2 0.8 2.2 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 KUM61758.1 - 1.4e-12 47.6 0.0 3.4e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KUM61758.1 - 5.7e-06 26.1 1.2 1.9e-05 24.4 0.3 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 KUM61758.1 - 0.00067 19.5 0.5 0.0039 17.0 0.5 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KUM61758.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component Phosphatase PF15698.5 KUM61758.1 - 0.089 11.9 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphatase Glyco_hydro_30 PF02055.16 KUM61759.1 - 5e-34 117.8 2.6 7.8e-34 117.2 2.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 KUM61759.1 - 5.5e-10 39.3 1.0 1.2e-09 38.3 1.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 KUM61759.1 - 0.00036 19.9 2.1 0.0011 18.3 0.1 2.1 1 1 0 2 2 2 1 Glycosyl hydrolase family 59 MFS_1 PF07690.16 KUM61760.1 - 3.6e-33 115.0 28.4 1.2e-32 113.3 26.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3139 PF11337.8 KUM61760.1 - 0.18 12.4 0.3 2.2 9.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) Pyr_redox_2 PF07992.14 KUM61761.1 - 1.4e-11 44.2 0.0 1.8e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM61761.1 - 2.7e-09 37.5 0.2 5.9e-09 36.4 0.2 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MFS_2 PF13347.6 KUM61762.1 - 1.2e-08 33.9 12.2 1.2e-08 33.9 12.2 1.8 2 1 0 2 2 2 1 MFS/sugar transport protein PUCC PF03209.15 KUM61762.1 - 9e-05 21.6 3.3 0.00016 20.8 3.3 1.4 1 0 0 1 1 1 1 PUCC protein STE PF02200.16 KUM61763.1 - 5.1e-55 184.6 0.0 7.8e-55 184.0 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KUM61763.1 - 2.6e-12 46.5 10.4 1.8e-06 28.0 0.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KUM61763.1 - 6.2e-09 35.9 11.9 9.4e-09 35.3 4.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KUM61763.1 - 1.3e-08 34.9 8.4 0.00092 19.9 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KUM61763.1 - 0.00032 20.6 4.3 0.0015 18.5 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KUM61763.1 - 0.004 17.4 0.1 0.92 9.9 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 KUM61763.1 - 0.049 14.3 2.4 0.092 13.5 2.4 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-Di19 PF05605.12 KUM61763.1 - 0.12 12.7 3.0 0.32 11.3 3.0 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding NOA36 PF06524.12 KUM61763.1 - 0.14 11.5 0.3 0.22 10.8 0.3 1.2 1 0 0 1 1 1 0 NOA36 protein zf-C2HC_2 PF13913.6 KUM61763.1 - 0.16 11.9 5.4 1.9 8.5 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KUM61763.1 - 1.8 8.4 9.9 9.1 6.1 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain GMC_oxred_N PF00732.19 KUM61765.1 - 1.6e-58 198.5 0.0 2.1e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM61765.1 - 5.2e-33 114.6 0.0 1.1e-32 113.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KUM61765.1 - 0.0033 17.6 0.0 0.0096 16.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KUM61765.1 - 0.018 14.1 0.1 0.4 9.7 0.3 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KUM61765.1 - 0.022 14.0 0.1 0.28 10.4 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM61765.1 - 0.071 12.4 0.1 0.39 9.9 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KUM61765.1 - 0.1 11.6 0.2 0.27 10.2 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein CoA_transf_3 PF02515.17 KUM61766.1 - 8.9e-66 222.5 0.0 3.3e-65 220.6 0.0 1.7 1 1 0 1 1 1 1 CoA-transferase family III SelP_N PF04592.14 KUM61767.1 - 5.7 6.3 7.1 9.7 5.5 7.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RNA_pol_I_A49 PF06870.12 KUM61768.1 - 3.3e-67 227.0 0.0 2.4e-66 224.2 0.0 1.9 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor PEHE PF15275.6 KUM61768.1 - 0.97 10.1 3.4 0.86 10.2 1.3 2.0 1 1 1 2 2 2 0 PEHE domain LacI PF00356.21 KUM61768.1 - 4.9 7.0 5.8 6.1 6.7 1.2 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family MFS_1 PF07690.16 KUM61769.1 - 4.1e-35 121.4 32.9 5.1e-35 121.0 30.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L41 PF05162.13 KUM61769.1 - 2.4e-08 33.9 29.2 4.8e-08 32.9 29.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L41 Aminotran_1_2 PF00155.21 KUM61771.1 - 9e-86 288.3 0.0 1.1e-85 287.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KUM61771.1 - 2.4e-06 26.4 0.0 4.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KUM61771.1 - 0.00033 20.1 0.2 0.00097 18.5 0.2 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KUM61771.1 - 0.00048 19.2 0.0 0.00085 18.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KUM61771.1 - 0.038 13.3 0.1 0.06 12.6 0.1 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase ADH_N PF08240.12 KUM61772.1 - 1.3e-27 95.9 0.9 2.6e-27 94.9 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM61772.1 - 6.5e-23 81.1 0.6 1.2e-22 80.3 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM61772.1 - 6.3e-05 24.0 0.1 0.0001 23.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KUM61772.1 - 0.023 14.0 1.2 0.033 13.5 1.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KUM61772.1 - 0.031 13.6 0.3 0.054 12.9 0.3 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 KUM61772.1 - 0.034 13.6 1.5 0.069 12.6 1.2 1.7 1 1 0 1 1 1 0 short chain dehydrogenase SNF2_N PF00176.23 KUM61773.1 - 5.1e-65 219.5 1.2 1.2e-64 218.3 1.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KUM61773.1 - 4e-49 166.4 21.9 4e-49 166.4 21.9 4.4 4 0 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 KUM61773.1 - 5.3e-19 68.6 0.0 1.3e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM61773.1 - 8.2e-07 29.2 1.7 1.4e-06 28.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KUM61773.1 - 0.0041 16.9 0.0 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KUM61773.1 - 0.016 14.4 1.1 0.079 12.1 0.0 2.7 3 1 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 Dimeth_Pyl PF09505.10 KUM61774.1 - 0.2 10.1 0.0 0.22 10.0 0.0 1.0 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) AA_permease_2 PF13520.6 KUM61775.1 - 5.4e-58 196.8 28.3 6.3e-58 196.6 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease Baculo_11_kDa PF06143.11 KUM61775.1 - 5.3 6.7 5.5 9.7 5.8 0.3 3.1 3 0 0 3 3 3 0 Baculovirus 11 kDa family Na_H_Exchanger PF00999.21 KUM61776.1 - 3.4e-65 220.3 34.8 4.2e-65 220.0 34.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4396 PF14342.6 KUM61776.1 - 3 8.2 8.0 1.5 9.2 3.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4396) Dioxygenase_C PF00775.21 KUM61777.1 - 1.2e-10 41.1 0.1 2.5e-08 33.6 0.1 2.2 1 1 0 1 1 1 1 Dioxygenase PRK PF00485.18 KUM61778.1 - 1.8e-05 24.5 0.0 3.6e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KUM61778.1 - 3.5e-05 24.3 0.0 8.1e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KUM61778.1 - 0.0062 16.7 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KUM61778.1 - 0.007 16.9 0.1 0.027 15.0 0.1 1.9 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KUM61778.1 - 0.014 15.8 0.1 0.037 14.4 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KUM61778.1 - 0.024 14.9 0.3 0.062 13.5 0.1 2.0 2 1 0 2 2 2 0 AAA domain CPT PF07931.12 KUM61778.1 - 0.024 14.5 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.6 KUM61778.1 - 0.06 13.8 0.0 0.23 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KUM61778.1 - 0.081 13.2 0.0 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KUM61778.1 - 0.09 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein KTI12 PF08433.10 KUM61778.1 - 0.2 11.1 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Cytidylate_kin PF02224.18 KUM61778.1 - 0.2 11.3 0.1 0.29 10.8 0.1 1.4 1 1 0 1 1 1 0 Cytidylate kinase Drf_GBD PF06371.13 KUM61781.1 - 8.2e-18 64.6 2.6 5.4e-11 42.4 0.0 2.7 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Xpo1 PF08389.12 KUM61781.1 - 0.013 15.6 0.0 0.29 11.2 0.0 2.3 2 0 0 2 2 2 0 Exportin 1-like protein Nramp PF01566.18 KUM61783.1 - 4.7e-95 318.6 18.5 4.7e-95 318.6 18.5 1.8 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein ZYG-11_interact PF05884.12 KUM61783.1 - 0.0073 15.8 2.1 0.017 14.5 2.1 1.6 1 0 0 1 1 1 1 Interactor of ZYG-11 Snf7 PF03357.21 KUM61785.1 - 4e-43 147.0 15.0 5e-43 146.7 15.0 1.0 1 0 0 1 1 1 1 Snf7 DUF3584 PF12128.8 KUM61785.1 - 0.001 16.7 4.6 0.0012 16.4 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF4201 PF13870.6 KUM61785.1 - 0.0011 18.7 10.1 0.0015 18.3 6.8 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) Zwint PF15556.6 KUM61785.1 - 0.0011 18.5 4.8 0.0014 18.2 4.8 1.3 1 0 0 1 1 1 1 ZW10 interactor NPV_P10 PF05531.12 KUM61785.1 - 0.0014 19.1 7.3 0.055 13.9 1.1 2.7 3 0 0 3 3 3 2 Nucleopolyhedrovirus P10 protein AF0941-like PF14591.6 KUM61785.1 - 0.043 14.4 4.8 0.07 13.7 4.8 1.3 1 0 0 1 1 1 0 AF0941-like DUF848 PF05852.11 KUM61785.1 - 0.051 13.7 7.2 0.036 14.2 5.2 1.8 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Alpha-2-MRAP_C PF06401.11 KUM61785.1 - 0.059 13.3 5.2 0.096 12.6 3.2 2.0 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain bZIP_1 PF00170.21 KUM61785.1 - 0.11 12.6 4.7 1.8 8.7 0.0 3.4 2 1 0 3 3 3 0 bZIP transcription factor FlaC_arch PF05377.11 KUM61785.1 - 0.16 12.4 8.6 4.4 7.8 0.0 3.4 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF5082 PF16888.5 KUM61785.1 - 0.24 11.7 9.0 2.5 8.4 4.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Atg14 PF10186.9 KUM61785.1 - 0.27 10.3 4.5 0.41 9.7 4.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Glutaredoxin PF00462.24 KUM61785.1 - 0.63 10.3 1.7 0.75 10.1 0.3 1.8 2 0 0 2 2 2 0 Glutaredoxin XhlA PF10779.9 KUM61785.1 - 1.4 9.1 7.2 9.6 6.5 0.0 3.4 3 1 1 4 4 4 0 Haemolysin XhlA adh_short PF00106.25 KUM61786.1 - 0.00045 19.7 0.2 0.00052 19.5 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.20 KUM61786.1 - 0.035 14.2 0.1 0.036 14.1 0.1 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thiolase_N PF00108.23 KUM61788.1 - 6.5e-73 245.3 3.0 6.5e-73 245.3 3.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KUM61788.1 - 1.7e-44 150.4 0.3 4.2e-44 149.1 0.3 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KUM61788.1 - 0.00071 19.2 1.0 0.0054 16.3 0.4 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KUM61788.1 - 0.046 13.6 1.5 10 6.1 0.1 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Glyco_hydro_43 PF04616.14 KUM61789.1 - 8.2e-70 235.4 3.4 1.2e-69 234.8 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KUM61789.1 - 3.3e-06 27.0 0.0 1.1e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain Acetyltransf_2 PF00797.17 KUM61790.1 - 1.9e-18 67.2 0.0 2.1e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 N-acetyltransferase MWFE PF15879.5 KUM61791.1 - 2.8e-20 72.2 0.0 3.3e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Beta_helix PF13229.6 KUM61792.1 - 2e-05 24.5 17.0 0.0065 16.3 12.8 2.4 1 1 1 2 2 2 2 Right handed beta helix region RraA-like PF03737.15 KUM61793.1 - 2.6e-27 95.8 0.0 3.8e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Aldolase/RraA MOZ_SAS PF01853.18 KUM61796.1 - 2.7e-74 248.7 0.0 5.2e-74 247.8 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KUM61796.1 - 8.6e-22 76.5 2.3 1.8e-21 75.5 2.3 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KUM61796.1 - 0.21 12.1 0.0 0.41 11.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PHD_4 PF16866.5 KUM61796.1 - 1.5 9.0 6.8 14 5.9 6.8 2.5 1 1 0 1 1 1 0 PHD-finger Complex1_51K PF01512.17 KUM61798.1 - 4.5e-46 156.5 0.0 7.2e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KUM61798.1 - 4.4e-29 100.4 0.3 8.5e-29 99.5 0.3 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KUM61798.1 - 1.3e-08 34.6 0.0 3.7e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 SLBB domain DUF3568 PF12092.8 KUM61798.1 - 0.26 11.4 0.5 0.53 10.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) SET PF00856.28 KUM61799.1 - 0.00044 20.7 0.0 0.001 19.5 0.0 1.7 2 0 0 2 2 2 1 SET domain Nuc_deoxyrib_tr PF05014.15 KUM61799.1 - 0.069 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase TRI12 PF06609.13 KUM61799.1 - 0.17 10.2 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) SAPS PF04499.15 KUM61800.1 - 2.4e-200 666.5 0.7 1.6e-198 660.5 0.0 2.6 3 0 0 3 3 3 2 SIT4 phosphatase-associated protein Glyco_hydro_26 PF02156.15 KUM61801.1 - 2.5e-70 237.4 1.1 2.9e-70 237.2 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Peptidase_C97 PF05903.14 KUM61802.1 - 0.00052 19.9 0.0 0.0008 19.3 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KUM61802.1 - 0.021 15.1 0.0 0.37 11.1 0.0 2.3 2 0 0 2 2 2 0 Lecithin retinol acyltransferase Nup96 PF12110.8 KUM61803.1 - 7.7e-82 274.7 3.1 1.2e-81 274.1 1.9 1.9 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KUM61803.1 - 5.4e-50 169.4 0.0 8.9e-50 168.7 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KUM61803.1 - 8.4e-07 29.8 59.2 8.8e-05 23.3 28.0 10.9 3 2 6 9 9 9 5 Nucleoporin FG repeat region MFS_1 PF07690.16 KUM61804.1 - 2.1e-49 168.3 27.9 2.4e-49 168.1 18.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM61804.1 - 0.0014 17.1 4.3 0.0021 16.5 4.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KUM61804.1 - 1.5 7.0 7.8 0.27 9.5 2.0 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3445 PF11927.8 KUM61805.1 - 3.6e-84 281.9 0.0 4.4e-84 281.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Exo5 PF09810.9 KUM61806.1 - 3.3e-139 464.5 0.0 4.1e-139 464.2 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KUM61806.1 - 0.047 13.6 0.0 14 5.5 0.0 2.9 2 1 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Mpv17_PMP22 PF04117.12 KUM61807.1 - 1.2e-15 57.5 0.4 1.2e-15 57.5 0.4 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF5427 PF10310.9 KUM61807.1 - 0.8 8.6 2.6 1.1 8.1 2.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) MFS_1 PF07690.16 KUM61808.1 - 1.3e-38 132.8 47.7 6.1e-38 130.7 42.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Histone PF00125.24 KUM61810.1 - 1e-51 174.7 2.5 1.1e-51 174.6 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KUM61810.1 - 6e-06 26.6 0.0 9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KUM61810.1 - 4.9e-05 23.4 0.5 7.4e-05 22.8 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KUM61810.1 - 6.5e-05 23.5 1.2 7.7e-05 23.3 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KUM61810.1 - 0.0032 17.7 0.3 0.0065 16.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KUM61810.1 - 0.026 14.6 0.2 0.042 13.9 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KUM61811.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KUM61811.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KUM61811.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KUM61811.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KUM61811.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KUM61811.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KUM61811.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KUM61811.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KUM61811.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region zf-C2H2 PF00096.26 KUM61812.1 - 4.5e-08 33.1 19.2 3.3e-05 24.1 1.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM61812.1 - 2.5e-06 27.9 13.3 0.0095 16.7 0.7 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 KUM61812.1 - 1.7 9.0 7.9 1.6 9.1 2.3 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 KUM61812.1 - 7.6 6.6 7.9 0.32 11.0 1.8 1.9 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 KUM61812.1 - 8.6 7.0 19.2 2.7 8.6 1.5 4.5 5 0 0 5 5 5 0 Zinc-finger double domain Sulfotransfer_4 PF17784.1 KUM61814.1 - 2.3e-74 249.9 0.0 2.8e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KUM61814.1 - 0.00031 21.2 0.1 0.0026 18.2 0.0 2.2 1 1 0 2 2 2 1 Sulfotransferase family P2 PF07194.11 KUM61815.1 - 0.045 13.8 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 P2 response regulator binding domain Clat_adaptor_s PF01217.20 KUM61816.1 - 9.1e-56 187.7 2.0 1.1e-55 187.5 2.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Cys_Met_Meta_PP PF01053.20 KUM61817.1 - 9.7e-62 208.7 0.0 2.9e-61 207.1 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KUM61817.1 - 0.004 16.4 0.0 0.0081 15.4 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KUM61817.1 - 0.0094 15.3 0.0 0.19 11.0 0.0 2.4 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KUM61817.1 - 0.025 13.5 0.0 0.051 12.5 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Ist1 PF03398.14 KUM61818.1 - 8.3e-43 146.1 1.2 2.8e-22 79.4 3.7 2.3 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway MSA-2c PF12238.8 KUM61818.1 - 0.82 9.6 0.0 0.82 9.6 0.0 2.0 2 0 0 2 2 2 0 Merozoite surface antigen 2c DUF3169 PF11368.8 KUM61819.1 - 0.015 14.8 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) PAP_PilO PF06864.12 KUM61819.1 - 0.22 10.3 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Fungal_trans_2 PF11951.8 KUM61820.1 - 1.1e-36 126.5 0.3 1.6e-36 126.0 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM61820.1 - 6.5e-07 29.4 10.2 1.5e-06 28.2 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cutinase PF01083.22 KUM61821.1 - 1.2e-32 113.3 1.4 1.9e-32 112.6 1.4 1.3 1 0 0 1 1 1 1 Cutinase LCM PF04072.14 KUM61821.1 - 4.6e-20 72.4 0.0 7.2e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase PE-PPE PF08237.11 KUM61821.1 - 0.00021 20.9 0.3 0.00037 20.1 0.3 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KUM61821.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) SUN PF03856.13 KUM61822.1 - 3e-80 269.2 5.7 4.3e-80 268.7 5.7 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) SOG2 PF10428.9 KUM61822.1 - 6.1 5.9 36.0 9.8 5.2 36.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Glyco_transf_22 PF03901.17 KUM61823.1 - 7.2e-83 279.1 21.0 8.3e-83 278.9 21.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.14 KUM61824.1 - 1.6e-45 154.6 0.4 1.6e-45 154.6 0.4 2.1 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region PRP3 PF08572.10 KUM61825.1 - 2e-70 237.1 11.2 2e-70 237.1 11.2 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KUM61825.1 - 3e-46 157.1 0.0 3e-46 157.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.17 KUM61826.1 - 4.7e-86 288.5 0.3 9.1e-86 287.6 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KUM61826.1 - 7.5e-67 224.7 0.1 1.6e-66 223.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KUM61826.1 - 1.1e-31 109.9 0.0 4e-30 104.8 0.0 3.1 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KUM61826.1 - 3.3e-27 95.6 1.1 2.6e-26 92.7 0.0 3.0 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KUM61826.1 - 3e-16 59.3 0.0 3e-16 59.3 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 Phage_TTP_13 PF16463.5 KUM61827.1 - 0.18 11.3 0.5 0.3 10.6 0.5 1.5 1 1 0 1 1 1 0 Phage tail tube protein family ADH_N PF08240.12 KUM61828.1 - 2.8e-29 101.2 0.1 4.8e-29 100.4 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM61828.1 - 1.4e-17 63.9 0.0 2.1e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM61828.1 - 0.0048 17.9 0.0 0.0084 17.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KUM61828.1 - 0.005 16.7 0.1 0.0098 15.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 KUM61828.1 - 0.18 11.0 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DEAD_2 PF06733.15 KUM61829.1 - 6.8e-56 188.7 0.7 1.1e-55 188.0 0.1 1.7 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 KUM61829.1 - 1.2e-48 165.3 6.2 7.1e-45 153.0 0.7 2.9 4 0 0 4 4 4 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KUM61829.1 - 2e-43 148.5 0.0 5.7e-43 147.0 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 KUM61829.1 - 6.1e-05 23.1 0.2 0.0035 17.4 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KUM61829.1 - 0.0043 16.8 0.0 0.65 9.7 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KUM61829.1 - 0.0045 17.3 1.1 2.4 8.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 KUM61829.1 - 0.029 13.6 0.3 1.7 7.8 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.23 KUM61829.1 - 0.067 11.9 0.0 0.46 9.1 0.0 2.0 1 1 0 1 1 1 0 SNF2 family N-terminal domain zf-RING_2 PF13639.6 KUM61830.1 - 9.4e-08 32.3 9.0 2e-07 31.2 9.0 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KUM61830.1 - 5.7e-05 23.2 6.2 0.00014 22.0 6.2 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KUM61830.1 - 0.00013 21.9 2.2 0.00034 20.6 2.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KUM61830.1 - 0.00018 21.7 8.0 0.00044 20.5 8.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KUM61830.1 - 0.00031 20.5 9.6 0.00079 19.3 9.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KUM61830.1 - 0.005 16.7 8.4 0.01 15.7 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KUM61830.1 - 0.16 12.1 7.6 0.4 10.9 7.6 1.8 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.22 KUM61830.1 - 0.2 11.6 5.8 0.47 10.4 5.8 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 KUM61830.1 - 0.28 10.8 6.2 0.58 9.8 6.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KUM61830.1 - 0.36 10.7 6.6 5.6 6.9 0.5 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KUM61830.1 - 0.58 10.5 8.2 1.1 9.6 8.2 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 KUM61830.1 - 0.92 9.4 5.7 2.2 8.2 5.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KUM61830.1 - 0.96 9.3 5.7 0.59 9.9 2.9 2.1 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_9 PF13901.6 KUM61830.1 - 1.5 8.7 6.8 13 5.7 7.3 2.1 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD PF00628.29 KUM61830.1 - 2.5 8.1 7.2 4.8 7.2 7.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 KUM61830.1 - 2.9 8.0 5.7 6.4 6.9 5.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KUM61830.1 - 4.8 7.1 6.2 11 5.9 6.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 MFS_1 PF07690.16 KUM61831.1 - 3.5e-48 164.3 62.8 8e-47 159.9 61.8 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM61831.1 - 7.6e-24 84.1 11.1 1.3e-23 83.3 11.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM61831.1 - 2.5e-13 49.7 16.3 2.5e-13 49.7 16.3 3.0 1 1 2 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KUM61831.1 - 0.0022 16.4 2.5 0.0022 16.4 2.5 4.0 3 2 1 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 KUM61831.1 - 4 5.9 42.6 0.0046 15.6 10.5 4.0 3 2 1 4 4 4 0 MFS/sugar transport protein Ribosomal_L35Ae PF01247.18 KUM61835.1 - 1.2e-42 144.0 0.3 1.7e-42 143.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KUM61835.1 - 0.0011 19.2 0.0 0.48 10.7 0.0 2.3 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.9 KUM61835.1 - 0.058 13.2 1.1 0.35 10.7 0.1 2.2 1 1 1 2 2 2 0 Putative transposon-encoded protein (DUF2080) MFS_2 PF13347.6 KUM61837.1 - 5.7e-11 41.6 11.0 5.7e-11 41.6 11.0 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 KUM61837.1 - 7.3e-05 21.8 0.0 0.00021 20.3 0.0 2.1 1 1 0 1 1 1 1 MFS_1 like family G6PD_C PF02781.16 KUM61838.1 - 3.9e-116 387.3 0.0 6.4e-116 386.6 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KUM61838.1 - 4.2e-62 209.9 0.1 7.4e-62 209.1 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.8 KUM61838.1 - 0.062 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) HUN PF08729.10 KUM61838.1 - 0.076 13.0 0.2 0.18 11.8 0.2 1.6 1 0 0 1 1 1 0 HPC2 and ubinuclein domain F-box-like PF12937.7 KUM61839.1 - 4.1e-08 33.0 0.0 0.0004 20.2 0.0 3.0 3 0 0 3 3 3 2 F-box-like Cytokin_check_N PF10407.9 KUM61839.1 - 0.0077 16.2 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus EF-hand_1 PF00036.32 KUM61840.1 - 4.7e-22 75.8 0.8 4.4e-08 32.1 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KUM61840.1 - 6.7e-20 69.3 1.2 4.8e-05 23.0 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KUM61840.1 - 1.3e-18 67.1 0.1 1.3e-08 35.2 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KUM61840.1 - 3.9e-18 65.0 0.3 1.3e-08 34.5 0.0 3.5 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KUM61840.1 - 1.2e-14 53.1 2.1 0.00082 18.8 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_14 PF17959.1 KUM61840.1 - 0.17 12.2 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain NACHT_N PF17100.5 KUM61841.1 - 5.1e-24 85.4 1.5 1.3e-23 84.1 1.5 1.7 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_16 PF13191.6 KUM61841.1 - 0.052 13.9 0.1 0.74 10.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Ank_2 PF12796.7 KUM61842.1 - 2e-42 143.6 7.5 5.5e-13 49.3 0.0 5.1 3 1 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM61842.1 - 3.5e-33 113.5 6.2 4.5e-07 30.3 0.0 7.1 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KUM61842.1 - 2.4e-32 109.9 20.0 0.00017 21.9 0.0 9.6 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 KUM61842.1 - 9.4e-32 108.7 13.7 4.4e-08 33.2 0.1 7.4 3 1 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM61842.1 - 1.5e-29 98.8 9.5 0.00048 20.4 0.0 9.8 10 0 0 10 10 10 8 Ankyrin repeat LIAS_N PF16881.5 KUM61843.1 - 3.4e-26 91.8 0.0 6.4e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KUM61843.1 - 1.8e-14 54.5 0.0 2.8e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HAD PF12710.7 KUM61844.1 - 3.6e-21 76.4 0.0 5.9e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KUM61844.1 - 2.3e-16 60.7 0.1 3.6e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KUM61844.1 - 5.1e-10 39.5 0.1 4.2e-08 33.3 0.0 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KUM61844.1 - 4.9e-07 30.0 0.0 3.5e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KUM61844.1 - 0.069 12.5 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Putative Phosphatase E3_binding PF02817.17 KUM61844.1 - 0.11 12.8 0.1 23 5.4 0.0 2.5 2 0 0 2 2 2 0 e3 binding domain S6PP PF05116.13 KUM61844.1 - 0.13 11.7 0.1 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase_like PF13242.6 KUM61844.1 - 0.17 12.0 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like PAPS_reduct PF01507.19 KUM61845.1 - 5.3e-42 143.8 0.0 7.3e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family zf-MYND PF01753.18 KUM61846.1 - 6e-08 32.6 7.8 6e-08 32.6 7.8 1.8 2 0 0 2 2 2 1 MYND finger SelK_SelG PF10961.8 KUM61847.1 - 2.6e-06 27.9 17.3 3.3e-05 24.4 17.3 2.0 1 1 0 1 1 1 1 Selenoprotein SelK_SelG GRP PF07172.11 KUM61847.1 - 0.00016 22.3 2.4 0.00021 21.9 2.4 1.1 1 0 0 1 1 1 1 Glycine rich protein family DeoC PF01791.9 KUM61848.1 - 8.6e-19 68.1 0.4 1.2e-18 67.6 0.4 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.21 KUM61848.1 - 0.061 12.5 1.2 0.094 11.9 1.2 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase WD40 PF00400.32 KUM61849.1 - 1.1e-09 38.8 7.9 0.00015 22.5 0.2 5.1 6 0 0 6 6 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM61849.1 - 8.2e-06 26.0 0.0 1.9 8.8 0.0 4.3 2 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KUM61849.1 - 0.0006 19.5 1.3 0.0021 17.7 0.3 2.3 2 1 0 2 2 2 1 PQQ-like domain WD40_alt PF14077.6 KUM61849.1 - 0.078 12.9 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Alternative WD40 repeat motif Fez1 PF06818.15 KUM61849.1 - 0.12 12.8 9.0 0.19 12.1 9.0 1.2 1 0 0 1 1 1 0 Fez1 TMF_TATA_bd PF12325.8 KUM61849.1 - 0.21 11.8 9.6 0.76 10.0 9.4 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FAM76 PF16046.5 KUM61849.1 - 0.26 10.6 3.3 0.36 10.1 3.3 1.2 1 0 0 1 1 1 0 FAM76 protein PQQ_3 PF13570.6 KUM61849.1 - 0.27 11.8 4.1 6.6 7.4 0.1 3.8 3 1 1 4 4 4 0 PQQ-like domain DUF4140 PF13600.6 KUM61849.1 - 0.3 11.5 10.8 30 5.2 9.9 2.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SKA1 PF07160.12 KUM61849.1 - 0.38 10.6 6.6 0.64 9.8 6.6 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Gon7 PF08738.10 KUM61849.1 - 0.45 10.6 3.9 1 9.4 3.9 1.6 1 0 0 1 1 1 0 Gon7 family Atg14 PF10186.9 KUM61849.1 - 0.51 9.4 5.6 0.8 8.7 5.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KUM61849.1 - 1.3 9.6 11.2 2 8.9 11.2 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 KUM61849.1 - 2.6 5.9 4.5 3.5 5.4 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LPP PF04728.13 KUM61849.1 - 3.3 8.2 6.7 9.2 6.7 0.5 2.5 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Cep57_CLD_2 PF14197.6 KUM61849.1 - 3.3 7.9 12.1 5.8 7.1 12.1 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 GFA PF04828.14 KUM61851.1 - 1e-24 86.7 0.6 1.3e-24 86.3 0.6 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme SRF-TF PF00319.18 KUM61852.1 - 1.2e-23 82.3 0.2 1.8e-23 81.7 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1708 PF08101.11 KUM61853.1 - 2.8e-144 481.5 0.0 4.5e-144 480.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF1708 PF08101.11 KUM61854.1 - 0.0061 15.8 0.0 0.0089 15.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Glyco_hydro_125 PF06824.11 KUM61855.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Metal-independent alpha-mannosidase (GH125) Aminotran_1_2 PF00155.21 KUM61856.1 - 1e-40 140.0 0.0 1.3e-40 139.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 KUM61856.1 - 0.088 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III SIMPL PF04402.14 KUM61857.1 - 2.3e-12 47.8 0.0 2.6e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF3254 PF11630.8 KUM61857.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) adh_short PF00106.25 KUM61858.1 - 8.5e-32 110.2 0.2 1.1e-31 109.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM61858.1 - 7.9e-25 87.8 0.2 2.5e-24 86.2 0.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM61858.1 - 6.1e-15 55.6 0.1 8.7e-15 55.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KUM61858.1 - 5.5e-08 32.3 0.0 7.1e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KUM61858.1 - 0.002 17.6 0.1 0.0032 17.0 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 KUM61858.1 - 0.043 13.0 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TcdB_toxin_midN PF12256.8 KUM61858.1 - 0.083 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region DJ-1_PfpI PF01965.24 KUM61860.1 - 1.7e-09 37.7 0.0 3.1e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KUM61860.1 - 0.00012 21.8 0.0 0.0003 20.5 0.0 1.7 1 1 0 1 1 1 1 ThiJ/PfpI family-like Peptidase_C26 PF07722.13 KUM61860.1 - 0.037 13.8 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase C26 Bacteriocin_IIc PF10439.9 KUM61860.1 - 0.066 13.3 3.5 0.14 12.3 3.5 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide PCI PF01399.27 KUM61861.1 - 4.5e-22 78.6 0.9 1.3e-21 77.1 0.0 2.2 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KUM61861.1 - 1.1e-15 57.5 2.0 2.9e-15 56.1 2.0 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Ribonuclease_T2 PF00445.18 KUM61861.1 - 0.14 12.4 0.1 0.4 10.9 0.0 1.8 2 0 0 2 2 2 0 Ribonuclease T2 family ERp29 PF07749.12 KUM61861.1 - 2.7 9.0 8.0 0.97 10.4 0.1 3.3 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain FSH1 PF03959.13 KUM61862.1 - 8.7e-45 153.0 0.0 1e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KUM61862.1 - 0.003 18.2 2.7 0.0091 16.6 2.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KUM61862.1 - 0.0079 15.8 0.0 0.44 10.1 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KUM61862.1 - 0.042 13.1 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KUM61862.1 - 0.046 13.5 0.1 1.2 8.9 0.1 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase TP_methylase PF00590.20 KUM61863.1 - 5.9e-49 166.9 0.1 1.5e-48 165.6 0.1 1.6 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KUM61863.1 - 2.8e-15 56.6 0.0 6.3e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KUM61863.1 - 3.7e-12 45.7 0.1 6.3e-08 32.1 0.0 2.5 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KUM61863.1 - 2.2e-07 30.2 0.1 1.1e-06 27.9 0.1 2.2 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central RTA1 PF04479.13 KUM61865.1 - 1.9e-47 161.5 10.4 2.9e-47 161.0 10.4 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4401 PF14351.6 KUM61865.1 - 0.016 14.6 0.2 0.016 14.6 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) Tautomerase_3 PF14832.6 KUM61865.1 - 0.036 14.3 0.1 0.071 13.3 0.1 1.5 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme GWT1 PF06423.12 KUM61865.1 - 0.46 10.6 6.0 0.069 13.3 1.5 2.0 2 1 0 2 2 2 0 GWT1 Abhydrolase_6 PF12697.7 KUM61866.1 - 6.7e-14 53.0 7.5 1e-13 52.4 7.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM61866.1 - 7.4e-11 42.2 0.3 1.1e-10 41.6 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM61866.1 - 3.6e-07 29.7 0.0 4.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KUM61866.1 - 2.9e-05 24.3 0.0 3.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KUM61866.1 - 0.005 16.5 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.25 KUM61866.1 - 0.017 15.0 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 KUM61866.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KUM61866.1 - 0.14 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DIOX_N PF14226.6 KUM61867.1 - 8.5e-18 65.2 0.0 2.1e-17 64.0 0.0 1.7 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KUM61867.1 - 1.6e-15 57.4 0.0 5.4e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KUM61868.1 - 4.5e-21 75.8 0.0 7.2e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KUM61868.1 - 2e-14 53.9 0.0 5.6e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1877 PF08974.10 KUM61868.1 - 0.047 13.8 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) DUF1729 PF08354.10 KUM61869.1 - 6.4e-139 462.7 0.0 1e-138 462.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KUM61869.1 - 5.6e-63 213.4 0.0 2.3e-62 211.3 0.0 1.9 2 0 0 2 2 2 1 Acyl transferase domain FAS_meander PF17951.1 KUM61869.1 - 8.6e-32 110.0 0.0 2.1e-31 108.7 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 KUM61869.1 - 7.9e-29 101.1 0.0 2.9e-28 99.2 0.0 1.9 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 KUM61869.1 - 1.3e-24 86.1 0.0 2.6e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KUM61869.1 - 1.9e-12 47.5 0.0 2.9e-11 43.6 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Dynein_heavy PF03028.15 KUM61869.1 - 0.1 12.7 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain Beta_elim_lyase PF01212.21 KUM61870.1 - 8.6e-55 186.1 0.1 1e-54 185.8 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KUM61870.1 - 0.0044 16.2 0.0 0.0069 15.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KUM61870.1 - 0.019 14.3 0.0 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family ABC_tran PF00005.27 KUM61871.1 - 2.8e-58 196.3 0.0 3.9e-32 111.6 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KUM61871.1 - 5.5e-32 111.5 25.8 7.3e-21 75.0 9.4 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_22 PF13401.6 KUM61871.1 - 9.3e-10 38.9 0.3 0.001 19.4 0.1 3.3 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.19 KUM61871.1 - 1.7e-09 37.4 0.4 0.11 11.9 0.5 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KUM61871.1 - 1.5e-07 31.0 0.1 0.024 14.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NB-ARC PF00931.22 KUM61871.1 - 2.3e-07 30.3 0.0 0.012 14.8 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain AAA_23 PF13476.6 KUM61871.1 - 5.8e-07 30.2 0.2 0.0026 18.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KUM61871.1 - 1.3e-06 28.4 0.0 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 KUM61871.1 - 2.1e-06 27.9 0.0 0.014 15.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KUM61871.1 - 6.5e-06 26.6 0.1 0.069 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KUM61871.1 - 1.6e-05 24.8 1.8 0.037 13.8 0.0 3.9 4 1 0 5 5 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KUM61871.1 - 2.4e-05 24.9 0.0 0.069 13.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KUM61871.1 - 3.2e-05 24.0 0.0 0.27 11.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 KUM61871.1 - 8.4e-05 23.0 0.2 0.061 13.7 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KUM61871.1 - 0.00018 20.6 0.0 0.34 9.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_15 PF13175.6 KUM61871.1 - 0.00018 21.3 0.0 0.44 10.2 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 KUM61871.1 - 0.00021 21.6 0.0 0.74 10.2 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 KUM61871.1 - 0.00041 19.9 0.0 0.58 9.7 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 KUM61871.1 - 0.00044 19.9 0.4 0.81 9.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KUM61871.1 - 0.0014 18.4 0.0 0.36 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 KUM61871.1 - 0.002 17.9 0.0 1.9 8.2 0.1 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.21 KUM61871.1 - 0.0024 17.3 0.1 0.27 10.6 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MobB PF03205.14 KUM61871.1 - 0.0027 17.6 0.1 1 9.3 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.9 KUM61871.1 - 0.003 17.3 0.5 3.4 7.4 0.1 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 KUM61871.1 - 0.0038 17.0 0.1 5 6.8 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein NTPase_1 PF03266.15 KUM61871.1 - 0.0044 16.9 0.2 1.8 8.4 0.0 3.2 3 0 0 3 3 3 1 NTPase AAA_5 PF07728.14 KUM61871.1 - 0.0076 16.3 0.1 3.9 7.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KUM61871.1 - 0.0079 16.4 0.9 2.4 8.4 0.3 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KUM61871.1 - 0.009 15.9 0.1 2.4 8.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain PDR_assoc PF08370.11 KUM61871.1 - 0.0093 15.7 0.2 0.0093 15.7 0.2 2.2 2 0 0 2 2 1 1 Plant PDR ABC transporter associated ATPase PF06745.13 KUM61871.1 - 0.0094 15.3 0.1 3.9 6.7 0.0 3.1 3 0 0 3 3 3 0 KaiC Septin PF00735.18 KUM61871.1 - 0.021 14.1 0.0 4.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Septin Viral_helicase1 PF01443.18 KUM61871.1 - 0.022 14.5 0.1 2 8.1 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 KUM61871.1 - 0.028 14.4 0.0 6.2 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 KUM61871.1 - 0.033 14.0 0.1 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 KUM61871.1 - 0.034 14.4 0.2 25 5.1 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KUM61871.1 - 0.04 14.0 0.4 4 7.5 0.0 2.7 2 1 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.12 KUM61871.1 - 0.04 13.2 0.0 7 5.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.15 KUM61871.1 - 0.044 13.7 0.8 0.54 10.2 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain DUF87 PF01935.17 KUM61871.1 - 0.046 13.8 0.1 1.5 8.9 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KUM61871.1 - 0.075 12.4 0.9 0.75 9.1 0.1 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_30 PF13604.6 KUM61871.1 - 0.087 12.5 0.5 7.7 6.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 KUM61871.1 - 0.16 12.0 0.0 18 5.3 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_ATPase PF09818.9 KUM61871.1 - 0.16 10.7 1.9 18 4.0 0.0 3.4 4 0 0 4 4 4 0 Predicted ATPase of the ABC class Pox_A32 PF04665.12 KUM61871.1 - 0.23 10.9 0.7 6.9 6.0 0.0 2.6 3 0 0 3 3 2 0 Poxvirus A32 protein SbcCD_C PF13558.6 KUM61871.1 - 0.32 11.3 2.5 1.8 8.8 0.1 3.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit p450 PF00067.22 KUM61873.1 - 3.2e-58 197.6 0.0 4.3e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GerD PF17898.1 KUM61873.1 - 0.039 13.9 0.0 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 Spore germination GerD central core domain P5CR_dimer PF14748.6 KUM61875.1 - 9.3e-17 61.2 6.5 1.6e-16 60.4 6.5 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KUM61875.1 - 4.7e-12 46.3 0.0 1.2e-11 45.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KUM61875.1 - 0.0026 17.7 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 KUM61875.1 - 0.0044 17.3 0.0 0.012 15.8 0.0 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Fas_alpha_ACP PF18325.1 KUM61876.1 - 1.5e-50 171.7 0.0 2.6e-50 170.9 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 KUM61876.1 - 1.4e-31 109.7 0.0 3.6e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 KUM61876.1 - 2.8e-17 63.2 0.1 5e-17 62.3 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KUM61876.1 - 1.3e-12 47.8 0.0 6.5e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ATG16 PF08614.11 KUM61876.1 - 0.67 10.1 3.0 0.56 10.4 0.7 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Aminotran_4 PF01063.19 KUM61877.1 - 1.3e-21 77.5 0.0 1.6e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV 2OG-FeII_Oxy PF03171.20 KUM61878.1 - 1.1e-07 32.2 0.0 1.8e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 KUM61879.1 - 0 1193.0 0.0 1.2e-75 254.8 0.0 5.3 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.20 KUM61879.1 - 1.1e-156 522.1 0.0 7.4e-40 137.0 0.0 7.7 6 1 1 7 7 7 7 Condensation domain PP-binding PF00550.25 KUM61879.1 - 3.2e-51 171.6 10.9 3.2e-09 37.0 0.0 6.8 6 0 0 6 6 6 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM61879.1 - 1.2e-09 39.0 0.0 0.15 13.1 0.0 5.4 5 0 0 5 5 5 2 AMP-binding enzyme C-terminal domain AATase PF07247.12 KUM61879.1 - 0.0032 16.1 0.0 0.0063 15.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol acetyltransferase Plectin PF00681.20 KUM61879.1 - 0.044 13.7 0.0 1.3 9.0 0.0 3.4 4 0 0 4 4 4 0 Plectin repeat WES_acyltransf PF03007.16 KUM61879.1 - 0.088 12.6 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain 4HBT_2 PF13279.6 KUM61880.1 - 2.2e-06 28.1 0.0 3.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Abhydrolase_6 PF12697.7 KUM61881.1 - 0.00048 20.8 0.5 0.00067 20.3 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM61881.1 - 0.0021 17.7 0.1 0.0041 16.8 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold HLH PF00010.26 KUM61882.1 - 1.3e-11 44.2 1.2 2.1e-11 43.6 0.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Integrase_1 PF12835.7 KUM61882.1 - 0.041 14.0 1.0 0.061 13.4 1.0 1.3 1 0 0 1 1 1 0 Integrase CAP_N PF01213.19 KUM61882.1 - 2.5 7.5 11.0 0.66 9.4 0.7 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal adh_short PF00106.25 KUM61883.1 - 8.2e-07 28.7 0.0 2.6e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM61883.1 - 1.6e-05 24.6 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 KUM61884.1 - 8.3e-13 48.4 0.2 1.2e-11 44.7 0.2 2.6 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM61884.1 - 2e-05 25.7 0.0 4.6e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM61884.1 - 0.00019 21.3 0.0 0.064 13.1 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KUM61884.1 - 0.0046 16.5 0.1 0.0065 16.0 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus MFS_1 PF07690.16 KUM61885.1 - 1.2e-42 146.1 57.6 1.2e-42 146.1 57.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 KUM61886.1 - 3.2e-10 39.9 11.3 5.2e-10 39.3 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM61886.1 - 0.0028 16.8 0.1 0.0051 15.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.7 KUM61887.1 - 3.8e-07 31.0 0.0 4.2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM61887.1 - 9.5e-07 28.7 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KUM61887.1 - 1.4e-05 24.0 0.0 2.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 KUM61887.1 - 1.6e-05 24.6 0.0 2.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KUM61887.1 - 3.9e-05 23.0 0.0 6.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 KUM61887.1 - 4.9e-05 23.3 0.0 7.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KUM61887.1 - 0.0021 17.5 0.0 0.004 16.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KUM61887.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF1100 PF06500.11 KUM61887.1 - 0.02 13.7 0.0 0.038 12.8 0.0 1.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1100) ketoacyl-synt PF00109.26 KUM61888.1 - 8.5e-60 202.4 0.0 1.9e-59 201.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KUM61888.1 - 2.4e-56 190.5 0.2 6.9e-56 189.0 0.2 1.9 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KUM61888.1 - 1.3e-55 188.8 0.0 2.2e-55 188.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KUM61888.1 - 1.4e-44 152.9 0.2 2.3e-44 152.2 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KUM61888.1 - 6.4e-33 113.3 1.0 2.5e-32 111.4 0.8 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KUM61888.1 - 4.9e-20 72.9 0.0 1.7e-19 71.1 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KUM61888.1 - 1.2e-19 70.8 0.0 3.7e-19 69.2 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KUM61888.1 - 4.2e-17 62.3 0.0 1.1e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KUM61888.1 - 1.6e-09 37.5 0.3 2.4e-08 33.7 0.1 2.8 3 0 0 3 3 3 1 short chain dehydrogenase PP-binding PF00550.25 KUM61888.1 - 1.5e-05 25.3 0.0 3.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KUM61888.1 - 0.00012 21.7 0.8 0.00041 20.0 0.1 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ACP_syn_III PF08545.10 KUM61888.1 - 0.00035 20.4 0.4 0.15 12.0 0.0 4.1 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SAT PF16073.5 KUM61888.1 - 0.00066 19.5 0.0 0.0064 16.2 0.0 2.3 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ADH_N PF08240.12 KUM61888.1 - 0.00071 19.4 0.8 0.0019 18.1 0.8 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2167 PF09935.9 KUM61888.1 - 0.084 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) RIBIOP_C PF04950.12 KUM61889.1 - 5.4e-95 318.2 0.0 5.4e-95 318.2 0.0 1.8 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KUM61889.1 - 1.1e-28 99.1 0.0 4.1e-28 97.3 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 KUM61889.1 - 9e-06 26.0 0.4 2.6e-05 24.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KUM61889.1 - 0.0001 22.8 0.0 0.00029 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KUM61889.1 - 0.00016 21.8 0.0 0.0005 20.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KUM61889.1 - 0.00055 20.5 1.0 0.0013 19.3 0.0 2.1 2 0 0 2 2 1 1 ABC transporter MMR_HSR1 PF01926.23 KUM61889.1 - 0.00055 20.0 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KUM61889.1 - 0.00059 19.4 0.0 0.12 11.9 0.0 2.6 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 KUM61889.1 - 0.0015 18.5 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KUM61889.1 - 0.0019 18.6 0.0 0.0036 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KUM61889.1 - 0.0022 18.4 0.0 0.0053 17.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KUM61889.1 - 0.0091 15.2 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain cobW PF02492.19 KUM61889.1 - 0.013 15.1 0.1 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KUM61889.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KUM61889.1 - 0.02 15.1 0.1 0.07 13.4 0.1 2.0 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KUM61889.1 - 0.023 14.1 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KUM61889.1 - 0.023 14.4 0.1 0.071 12.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KUM61889.1 - 0.025 14.9 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KUM61889.1 - 0.03 14.3 0.0 0.085 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 KUM61889.1 - 0.039 13.8 0.1 0.16 11.9 0.1 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KUM61889.1 - 0.043 13.7 0.3 0.087 12.7 0.3 1.5 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 KUM61889.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KUM61889.1 - 0.046 13.6 1.8 0.056 13.4 0.0 2.0 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea Roc PF08477.13 KUM61889.1 - 0.049 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KUM61889.1 - 0.051 14.1 0.1 0.051 14.1 0.1 3.0 4 0 0 4 4 1 0 AAA domain AAA_5 PF07728.14 KUM61889.1 - 0.054 13.5 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 KUM61889.1 - 0.054 12.7 0.5 0.082 12.1 0.0 1.5 2 0 0 2 2 1 0 KAP family P-loop domain RsgA_GTPase PF03193.16 KUM61889.1 - 0.077 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 KUM61889.1 - 0.094 12.7 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KUM61889.1 - 0.097 12.2 0.4 0.25 10.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain PduV-EutP PF10662.9 KUM61889.1 - 0.11 12.3 0.1 0.62 9.8 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 KUM61889.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF5305 PF17231.2 KUM61890.1 - 0.041 13.3 0.0 0.052 13.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF3899 PF13038.6 KUM61890.1 - 0.17 12.4 1.0 4.9 7.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) UQ_con PF00179.26 KUM61891.1 - 5.2e-25 87.7 0.1 5.8e-25 87.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KUM61891.1 - 9e-06 25.4 0.0 2.1e-05 24.2 0.0 1.7 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 KUM61891.1 - 0.00018 21.7 0.0 0.0019 18.5 0.0 2.0 1 1 1 2 2 2 1 RWD domain Aminotran_1_2 PF00155.21 KUM61892.1 - 2.1e-19 70.0 0.0 2.5e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RNase_Zc3h12a PF11977.8 KUM61892.1 - 0.034 13.9 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Aminotran_MocR PF12897.7 KUM61892.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase DUF3455 PF11937.8 KUM61893.1 - 1.7e-42 145.5 0.0 2.2e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) SF3b1 PF08920.10 KUM61894.1 - 8.1e-25 87.6 2.8 1.8e-23 83.3 2.8 2.5 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 KUM61894.1 - 2e-13 50.5 7.1 0.21 12.0 0.1 7.9 6 1 3 9 9 9 6 HEAT repeats HEAT_EZ PF13513.6 KUM61894.1 - 9.7e-12 45.1 0.9 0.077 13.5 0.0 7.0 7 0 0 7 7 7 2 HEAT-like repeat HEAT PF02985.22 KUM61894.1 - 2.5e-08 33.5 11.6 0.28 11.5 0.1 8.8 11 0 0 11 11 11 2 HEAT repeat Cnd1 PF12717.7 KUM61894.1 - 5.5e-08 33.0 2.2 0.77 9.8 0.0 6.5 5 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KUM61894.1 - 7.8e-05 23.2 0.1 7.5 7.2 0.0 4.9 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KUM61894.1 - 0.00049 20.0 1.7 0.84 9.5 0.1 5.2 4 2 0 4 4 4 1 Domain of unknown function (DUF3385) NUC173 PF08161.12 KUM61894.1 - 0.0043 16.7 0.1 0.91 9.1 0.0 4.3 4 1 0 5 5 5 1 NUC173 domain MMS19_C PF12460.8 KUM61894.1 - 0.043 12.9 0.0 3.3 6.7 0.0 3.4 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KUM61894.1 - 0.1 12.1 0.2 1.3 8.6 0.0 2.7 3 0 0 3 3 3 0 CLASP N terminal zf-H2C2_2 PF13465.6 KUM61895.1 - 3.7e-10 39.8 14.6 3.7e-05 24.0 0.4 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KUM61895.1 - 1e-09 38.3 11.6 2.2e-05 24.7 4.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM61895.1 - 1.1e-06 29.0 10.9 0.0013 19.4 3.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KUM61895.1 - 5.6e-06 26.6 1.3 1.8e-05 25.0 1.3 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KUM61895.1 - 0.00012 22.0 2.4 0.00012 22.0 2.4 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KUM61895.1 - 0.00069 19.8 5.1 0.00073 19.8 1.8 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KUM61895.1 - 0.069 13.5 1.1 0.069 13.5 1.1 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Actin_micro PF17003.5 KUM61895.1 - 0.22 10.7 0.2 0.3 10.2 0.2 1.1 1 0 0 1 1 1 0 Putative actin-like family zf-C2H2_11 PF16622.5 KUM61895.1 - 0.24 11.2 6.4 4.9 7.0 0.5 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KUM61895.1 - 0.38 10.7 6.6 2.8 7.9 0.4 2.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type FAD_binding_2 PF00890.24 KUM61896.1 - 1.9e-26 93.1 0.1 2.5e-26 92.7 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.19 KUM61896.1 - 0.0091 15.4 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Spem1 PF15670.5 KUM61897.1 - 0.16 11.5 1.7 0.3 10.6 1.7 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 Sec1 PF00995.23 KUM61898.1 - 7.3e-114 382.1 0.0 8.3e-114 381.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Transposase_22 PF02994.14 KUM61898.1 - 0.081 13.1 0.3 0.35 11.1 0.0 2.2 3 0 0 3 3 3 0 L1 transposable element RBD-like domain Pkinase PF00069.25 KUM61900.1 - 1e-69 234.8 0.0 1.4e-69 234.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM61900.1 - 1.6e-35 122.7 0.0 2.3e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM61900.1 - 1.9e-05 24.2 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KUM61900.1 - 0.00052 18.9 0.0 0.0011 17.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KUM61900.1 - 0.0017 17.8 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KUM61900.1 - 0.01 15.4 0.0 0.036 13.6 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Telomere_reg-2 PF10193.9 KUM61903.1 - 1e-28 99.9 0.0 3e-27 95.2 0.0 3.1 3 0 0 3 3 3 1 Telomere length regulation protein APH PF01636.23 KUM61905.1 - 4.5e-05 23.5 0.0 5.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KUM61905.1 - 0.024 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PPK2 PF03976.14 KUM61906.1 - 0.05 13.1 0.1 0.05 13.1 0.1 1.0 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) Pkinase PF00069.25 KUM61908.1 - 3.6e-57 193.7 0.0 4.8e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM61908.1 - 1e-42 146.2 0.0 1.6e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM61908.1 - 7.9e-05 22.1 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KUM61908.1 - 0.0017 17.2 0.6 0.0068 15.2 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KUM61908.1 - 0.0025 17.8 0.1 0.024 14.5 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KUM61908.1 - 0.0049 16.3 0.1 0.011 15.1 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KUM61908.1 - 0.014 15.0 0.0 0.043 13.4 0.0 1.8 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KUM61908.1 - 0.058 13.0 0.1 0.18 11.4 0.1 1.8 1 1 0 1 1 1 0 RIO1 family GTP_EFTU PF00009.27 KUM61909.1 - 1.4e-65 220.5 0.0 1.9e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KUM61909.1 - 2e-34 117.9 0.0 6e-34 116.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KUM61909.1 - 1.9e-22 79.1 0.0 6.6e-22 77.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KUM61909.1 - 1.8e-12 47.2 0.0 5.9e-12 45.5 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KUM61909.1 - 1.2e-11 44.9 0.5 3.8e-11 43.2 0.2 2.2 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KUM61909.1 - 0.0003 20.8 0.0 0.00072 19.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase CLAG PF03805.13 KUM61909.1 - 0.1 10.1 0.2 0.14 9.7 0.2 1.1 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein PWI PF01480.17 KUM61910.1 - 7.4e-12 45.4 0.1 4.5e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 KUM61910.1 - 1.7e-06 27.8 0.3 6.9e-05 22.6 0.1 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KUM61910.1 - 2e-06 27.7 0.0 0.00068 19.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 KUM61910.1 - 0.0055 16.6 1.6 0.0095 15.8 1.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.11 KUM61910.1 - 2.7 8.1 7.3 0.7 10.0 1.2 2.6 2 1 1 3 3 3 0 RNA binding motif Borrelia_P83 PF05262.11 KUM61910.1 - 6.9 5.0 13.9 10 4.5 13.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Methyltransf_24 PF13578.6 KUM61911.1 - 1.2e-12 48.8 0.0 1.9e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KUM61911.1 - 4.2e-07 29.4 0.1 1.2e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase DUF1442 PF07279.11 KUM61911.1 - 1.2e-05 24.8 0.0 1.6e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1442) eIF3g PF12353.8 KUM61911.1 - 0.19 12.2 0.0 0.29 11.6 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Fungal_trans PF04082.18 KUM61912.1 - 5.6e-17 61.6 0.2 8.3e-17 61.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KUM61914.1 - 1.5e-30 106.3 14.5 2e-30 105.9 14.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM61914.1 - 1.3e-10 40.4 3.4 1.6e-10 40.1 3.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM61914.1 - 4.7e-10 38.9 6.5 6e-10 38.6 6.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3784 PF12650.7 KUM61914.1 - 0.041 14.1 0.2 0.041 14.1 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3784) MFS_Mycoplasma PF07672.13 KUM61914.1 - 0.092 12.0 8.7 0.048 12.9 1.4 2.2 1 1 1 2 2 2 0 Mycoplasma MFS transporter DUF1772 PF08592.11 KUM61914.1 - 0.66 10.3 8.8 0.74 10.1 0.3 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF1772) FA_desaturase PF00487.24 KUM61915.1 - 0.66 9.8 6.3 0.062 13.1 2.1 1.4 2 0 0 2 2 2 0 Fatty acid desaturase LapA_dom PF06305.11 KUM61915.1 - 0.94 9.3 7.9 0.41 10.5 1.0 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 KUM61917.1 - 0.015 14.7 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain HEAT PF02985.22 KUM61918.1 - 3.1e-07 30.1 0.6 0.07 13.4 0.0 4.4 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 KUM61918.1 - 5.3e-07 29.8 0.1 1.2e-06 28.7 0.1 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KUM61918.1 - 0.00035 21.0 1.2 0.9 10.1 0.1 3.3 4 0 0 4 4 4 2 HEAT-like repeat Adaptin_N PF01602.20 KUM61918.1 - 0.014 14.0 0.0 0.02 13.5 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region HEAT_2 PF13646.6 KUM61918.1 - 0.015 15.7 0.1 0.17 12.3 0.1 2.4 1 1 2 3 3 3 0 HEAT repeats CoA_trans PF01144.23 KUM61918.1 - 0.051 13.0 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Coenzyme A transferase DUF3425 PF11905.8 KUM61919.1 - 8.6e-32 109.7 0.1 1.5e-31 109.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KUM61919.1 - 0.042 14.0 15.4 0.37 10.9 6.6 3.5 3 1 1 4 4 4 0 bZIP transcription factor Herpes_UL6 PF01763.16 KUM61919.1 - 0.19 10.2 2.5 0.26 9.8 2.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like ABC_tran_CTD PF16326.5 KUM61919.1 - 1.3 9.3 4.6 1.5 9.1 3.0 2.0 1 1 1 2 2 2 0 ABC transporter C-terminal domain bZIP_2 PF07716.15 KUM61919.1 - 2.9 8.1 9.8 2.4 8.3 2.9 2.5 2 0 0 2 2 2 0 Basic region leucine zipper MFS_1 PF07690.16 KUM61920.1 - 1.6e-48 165.4 40.7 1.6e-48 165.4 40.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM61920.1 - 7e-11 41.6 27.1 1.3e-10 40.7 27.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter zf-MYND PF01753.18 KUM61921.1 - 2.6e-09 37.0 12.2 4.4e-09 36.3 12.2 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KUM61921.1 - 0.14 12.5 9.8 0.53 10.6 9.7 1.9 1 1 1 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding APH PF01636.23 KUM61922.1 - 1.3e-07 31.8 0.0 2.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KUM61922.1 - 0.038 13.3 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Collectrin PF16959.5 KUM61922.1 - 0.19 11.5 0.0 0.53 10.1 0.0 1.7 1 0 0 1 1 1 0 Renal amino acid transporter Chromate_transp PF02417.15 KUM61924.1 - 7.8e-43 146.3 28.4 3.9e-37 127.8 11.1 2.7 3 0 0 3 3 3 2 Chromate transporter Amino_oxidase PF01593.24 KUM61926.1 - 2.3e-43 149.1 0.0 3e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KUM61926.1 - 2.6e-11 43.6 0.2 4.9e-11 42.7 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM61926.1 - 1.3e-07 31.5 0.5 3.4e-05 23.6 0.5 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KUM61926.1 - 6e-05 22.3 0.2 0.11 11.5 0.2 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KUM61926.1 - 0.00021 20.7 0.2 0.00071 18.9 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM61926.1 - 0.00031 21.3 0.4 0.0016 18.9 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KUM61926.1 - 0.00058 19.2 0.4 0.0015 17.9 0.1 1.7 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KUM61926.1 - 0.00058 18.7 0.7 0.0063 15.3 0.5 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KUM61926.1 - 0.00097 18.3 1.7 0.0017 17.5 1.2 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KUM61926.1 - 0.0011 18.4 1.1 0.0016 17.9 1.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KUM61926.1 - 0.0017 17.7 0.7 0.83 8.8 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KUM61926.1 - 0.0022 17.3 0.4 0.0047 16.2 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KUM61926.1 - 0.016 15.2 0.5 0.3 11.0 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 KUM61926.1 - 0.079 12.0 0.9 0.14 11.2 0.9 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AMP-binding PF00501.28 KUM61927.1 - 5.8e-31 107.5 0.0 1.1e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KUM61927.1 - 5.2e-27 94.6 0.0 8.3e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KUM61927.1 - 5.5e-10 39.5 0.2 2.9e-09 37.2 0.1 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.21 KUM61927.1 - 5.3e-09 35.9 0.0 8.7e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM61927.1 - 0.071 12.5 0.0 0.16 11.4 0.0 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF1129 PF06570.11 KUM61928.1 - 0.47 9.9 4.6 1.9 8.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) FAD_binding_4 PF01565.23 KUM61929.1 - 1.5e-14 53.9 0.5 1.5e-14 53.9 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KUM61929.1 - 1.3e-06 28.4 0.1 2.7e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like TyeA PF09059.10 KUM61929.1 - 0.19 11.9 0.0 0.42 10.7 0.0 1.5 1 0 0 1 1 1 0 TyeA MIP PF00230.20 KUM61930.1 - 1.4e-31 110.0 3.7 1.7e-31 109.7 3.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein DMT_YdcZ PF04657.13 KUM61930.1 - 0.036 14.3 3.7 0.091 13.0 0.1 2.8 2 1 1 3 3 3 0 Putative inner membrane exporter, YdcZ Gly-zipper_Omp PF13488.6 KUM61930.1 - 0.17 11.9 4.5 1.3 9.1 0.0 3.3 3 0 0 3 3 3 0 Glycine zipper Acetyltransf_1 PF00583.25 KUM61935.1 - 1e-10 41.9 0.0 1.4e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KUM61935.1 - 3.2e-07 30.3 0.2 4.6e-07 29.8 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KUM61935.1 - 1e-06 28.6 0.0 1.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KUM61935.1 - 0.00012 22.4 0.0 0.00024 21.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KUM61935.1 - 0.0057 16.7 0.3 0.0096 16.0 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KUM61936.1 - 6.1e-30 104.3 36.9 1.2e-29 103.4 29.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM61936.1 - 1.4e-08 34.0 7.4 1.4e-08 34.0 7.4 2.6 2 2 1 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.13 KUM61936.1 - 5.5e-07 28.4 2.1 5.5e-07 28.4 2.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) APG6_N PF17675.1 KUM61938.1 - 0.0017 18.8 7.8 0.0025 18.3 7.8 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region Mod_r PF07200.13 KUM61938.1 - 0.0024 18.0 6.3 0.004 17.3 6.3 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein FliJ PF02050.16 KUM61938.1 - 0.0025 18.0 5.2 0.004 17.4 5.2 1.3 1 0 0 1 1 1 1 Flagellar FliJ protein USP8_interact PF08941.10 KUM61938.1 - 0.021 14.7 1.3 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 USP8 interacting Phage_lysis PF03245.13 KUM61938.1 - 0.022 14.9 3.1 0.049 13.7 3.1 1.5 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein ADIP PF11559.8 KUM61938.1 - 0.041 14.0 8.6 0.075 13.1 8.6 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Cep57_CLD_2 PF14197.6 KUM61938.1 - 0.16 12.0 12.1 1.9 8.6 1.4 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Seryl_tRNA_N PF02403.22 KUM61938.1 - 0.21 11.8 5.2 0.5 10.6 5.2 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF848 PF05852.11 KUM61938.1 - 0.22 11.6 4.3 0.52 10.4 4.3 1.5 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4140 PF13600.6 KUM61938.1 - 0.53 10.8 5.5 2.1 8.9 0.9 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 KUM61938.1 - 0.76 9.6 8.1 0.26 11.1 2.9 2.1 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 KUM61938.1 - 0.89 10.0 9.2 0.06 13.8 3.5 1.9 2 0 0 2 2 2 0 Cell division protein ZapB TFIIA PF03153.13 KUM61938.1 - 1 9.3 14.6 1.5 8.7 14.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HAUS-augmin3 PF14932.6 KUM61938.1 - 2.3 7.7 8.3 3.5 7.1 8.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 KUM61938.1 - 2.4 7.0 8.4 4.4 6.1 8.4 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Cnn_1N PF07989.11 KUM61938.1 - 3.4 7.9 8.3 3.1 8.0 2.0 2.6 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 KxDL PF10241.9 KUM61938.1 - 5.7 7.3 9.8 2.1 8.7 6.0 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein WD40 PF00400.32 KUM61939.1 - 6.7e-37 124.9 17.9 2e-10 41.1 0.1 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM61939.1 - 7.3e-11 42.2 1.1 0.04 14.2 0.1 4.7 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KUM61939.1 - 4.4e-07 28.9 5.9 0.22 10.1 0.1 4.6 3 1 1 4 4 4 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KUM61939.1 - 2.4e-06 26.7 0.6 0.33 9.8 0.0 4.4 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KUM61939.1 - 0.00011 21.3 0.1 0.00011 21.3 0.1 2.4 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain DUF1513 PF07433.11 KUM61939.1 - 0.02 14.0 0.2 2.9 6.9 0.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Hira PF07569.11 KUM61939.1 - 0.029 14.1 1.6 0.74 9.5 0.5 3.4 2 1 1 3 3 3 0 TUP1-like enhancer of split Frtz PF11768.8 KUM61939.1 - 0.081 11.2 0.0 0.12 10.6 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz HPS3_N PF14761.6 KUM61939.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.7 1 1 0 1 1 1 0 Hermansky-Pudlak syndrome 3 LsmAD PF06741.13 KUM61940.1 - 1.6e-28 99.1 2.0 1.6e-28 99.1 2.0 1.9 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 KUM61940.1 - 1.6e-20 73.0 0.0 3.1e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain AIP3 PF03915.13 KUM61941.1 - 1.2e-153 512.1 0.8 1.2e-153 512.1 0.8 2.1 2 0 0 2 2 2 1 Actin interacting protein 3 Lectin_N PF03954.14 KUM61941.1 - 0.011 15.5 0.0 0.011 15.5 0.0 2.9 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain NPV_P10 PF05531.12 KUM61941.1 - 1 9.9 0.0 1 9.9 0.0 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Sec34 PF04136.15 KUM61941.1 - 1.1 9.1 3.6 6.6 6.6 0.1 3.0 3 0 0 3 3 3 0 Sec34-like family Mito_carr PF00153.27 KUM61942.1 - 7.8e-63 208.4 0.9 1.7e-21 76.0 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein Tctex-1 PF03645.13 KUM61943.1 - 1.1e-35 122.0 0.0 1.2e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family NLE PF08154.12 KUM61943.1 - 0.2 12.2 0.0 0.33 11.5 0.0 1.2 1 0 0 1 1 1 0 NLE (NUC135) domain Msg2_C PF12373.8 KUM61944.1 - 0.22 11.0 0.2 0.67 9.4 0.0 2.0 2 0 0 2 2 2 0 Major surface glycoprotein 2 C terminal tRNA-synt_1g PF09334.11 KUM61945.1 - 2.3e-82 276.9 0.0 1.2e-80 271.2 0.0 2.4 2 1 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KUM61945.1 - 4.3e-15 55.0 0.1 2.2e-11 42.8 0.0 3.3 2 2 2 4 4 4 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KUM61945.1 - 6.6e-07 29.0 0.0 0.0058 16.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 KUM61945.1 - 0.00034 20.6 0.0 0.00065 19.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA PALP PF00291.25 KUM61946.1 - 3.4e-48 164.6 0.3 5.6e-48 163.9 0.3 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ish1 PF10281.9 KUM61947.1 - 4e-07 30.2 0.0 5.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein DUF4129 PF13559.6 KUM61947.1 - 0.048 13.9 0.4 0.079 13.2 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) SAM_2 PF07647.17 KUM61947.1 - 0.13 12.4 0.1 0.27 11.4 0.1 1.5 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) NTF2 PF02136.20 KUM61948.1 - 2.7e-05 24.7 0.3 0.00011 22.7 0.3 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KUM61948.1 - 0.00072 19.5 0.0 0.002 18.1 0.0 1.8 1 1 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 DUF924 PF06041.11 KUM61949.1 - 7.6e-54 182.6 0.0 1.1e-53 182.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) S_layer_N PF05123.12 KUM61949.1 - 0.02 14.8 0.0 0.04 13.8 0.0 1.4 2 0 0 2 2 2 0 S-layer like family, N-terminal region Fungal_trans_2 PF11951.8 KUM61950.1 - 9.4e-23 80.6 1.6 2.5e-14 52.9 0.4 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM61950.1 - 6.6e-08 32.6 8.4 1.1e-07 31.8 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPTA PF01239.22 KUM61951.1 - 9.8e-34 114.1 25.7 1e-07 31.5 1.3 5.6 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_14 PF13428.6 KUM61951.1 - 0.035 14.9 1.2 0.68 10.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4269 PF14091.6 KUM61951.1 - 0.091 13.0 0.1 0.19 12.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4269) Sulfatase PF00884.23 KUM61952.1 - 2.8e-19 69.7 0.4 1.2e-18 67.5 0.4 2.0 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KUM61952.1 - 3.1e-07 30.3 0.0 6.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KUM61952.1 - 0.003 16.2 0.0 0.0044 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Arch_fla_DE PF04659.13 KUM61953.1 - 0.12 12.2 0.1 0.33 10.9 0.1 1.7 2 0 0 2 2 2 0 Archaeal flagella protein Ribosomal_L38e PF01781.18 KUM61954.1 - 7.2e-33 112.5 2.3 8.2e-33 112.3 2.3 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family DSBA PF01323.20 KUM61956.1 - 4e-19 69.2 0.0 4.5e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain cobW PF02492.19 KUM61958.1 - 8.2e-42 142.8 0.0 1.4e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KUM61958.1 - 0.0025 17.7 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 KUM61958.1 - 0.0044 17.6 0.1 0.018 15.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain CobW_C PF07683.14 KUM61958.1 - 0.0095 15.8 0.0 0.044 13.7 0.0 2.0 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.6 KUM61958.1 - 0.018 15.3 0.0 0.046 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KUM61958.1 - 0.061 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein Viral_helicase1 PF01443.18 KUM61958.1 - 0.15 11.8 0.7 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KUM61958.1 - 0.16 11.8 0.4 1.6 8.5 0.2 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Orn_Arg_deC_N PF02784.16 KUM61959.1 - 1.2e-80 270.4 0.0 1.6e-80 270.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KUM61959.1 - 1.5e-19 70.0 0.0 2.2e-19 69.5 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain BDV_P24 PF06595.11 KUM61960.1 - 0.027 14.4 0.0 0.035 14.0 0.0 1.1 1 0 0 1 1 1 0 Borna disease virus P24 protein LPD34 PF18852.1 KUM61960.1 - 0.05 13.2 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 Methyltransf_16 PF10294.9 KUM61961.1 - 2.9e-51 173.7 0.0 4.6e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 KUM61961.1 - 0.025 13.9 0.0 0.056 12.7 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain MTS PF05175.14 KUM61961.1 - 0.043 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain GidB PF02527.15 KUM61961.1 - 0.18 11.1 0.1 0.55 9.5 0.0 1.8 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G MFS_1 PF07690.16 KUM61963.1 - 3e-34 118.5 24.2 3e-34 118.5 24.2 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily DIOX_N PF14226.6 KUM61964.1 - 6.5e-19 68.8 0.0 3.8e-18 66.4 0.0 2.0 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KUM61964.1 - 2.3e-10 40.8 0.0 5.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4581 PF15167.6 KUM61964.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) FTO_CTD PF12934.7 KUM61965.1 - 0.054 13.2 0.5 0.12 12.2 0.5 1.5 1 0 0 1 1 1 0 FTO C-terminal domain TLD PF07534.16 KUM61966.1 - 3.1e-22 79.3 0.0 6.7e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 TLD DUF1773 PF08593.10 KUM61966.1 - 1.3e-05 26.1 0.9 3.8e-05 24.6 0.9 1.9 1 0 0 1 1 1 1 Domain of unknown function Abhydrolase_6 PF12697.7 KUM61968.1 - 9.2e-09 36.2 0.3 1.5e-08 35.5 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM61968.1 - 1.2e-05 24.8 0.0 2.4e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KUM61968.1 - 0.0028 17.3 0.0 0.0044 16.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KUM61968.1 - 0.0089 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Na_Pi_cotrans PF02690.15 KUM61968.1 - 0.04 14.0 0.3 0.068 13.3 0.3 1.3 1 0 0 1 1 1 0 Na+/Pi-cotransporter Cutinase PF01083.22 KUM61968.1 - 0.081 12.9 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 Cutinase RTA1 PF04479.13 KUM61969.1 - 9.1e-51 172.4 7.9 1.4e-50 171.8 7.9 1.3 1 0 0 1 1 1 1 RTA1 like protein Oxidored_q2 PF00420.24 KUM61969.1 - 2.4 7.9 7.3 0.91 9.2 1.4 2.8 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Glyco_hydro_61 PF03443.14 KUM61970.1 - 1.3e-68 231.0 0.1 1.6e-68 230.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3676 PF12429.8 KUM61970.1 - 0.2 11.5 0.0 2.2 8.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3676) Acetyltransf_3 PF13302.7 KUM61971.1 - 7e-21 75.4 0.0 9.1e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KUM61971.1 - 0.00096 18.8 1.2 0.76 9.5 0.5 2.6 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain DNA_pol_E_B PF04042.16 KUM61972.1 - 5.7e-45 153.3 0.0 1.3e-44 152.1 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KUM61972.1 - 4.2e-35 120.7 0.0 6.3e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain NMO PF03060.15 KUM61973.1 - 1.1e-52 179.6 1.7 1.5e-52 179.1 1.7 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KUM61973.1 - 1.8e-09 37.1 0.7 4.6e-09 35.7 0.7 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KUM61973.1 - 0.0051 15.9 2.6 0.0089 15.1 2.6 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Taxilin PF09728.9 KUM61974.1 - 1.8e-91 306.5 47.3 1.8e-91 306.5 47.3 1.7 2 0 0 2 2 2 1 Myosin-like coiled-coil protein DUF4201 PF13870.6 KUM61974.1 - 0.00054 19.8 15.3 0.00054 19.8 15.3 3.9 1 1 2 4 4 4 2 Domain of unknown function (DUF4201) UPF0242 PF06785.11 KUM61974.1 - 0.33 11.0 50.3 0.18 11.9 13.4 3.7 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus SLATT_4 PF18186.1 KUM61974.1 - 0.71 9.5 13.6 0.35 10.5 1.3 3.2 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 ERM PF00769.19 KUM61974.1 - 1.3 8.8 54.7 0.02 14.7 15.6 2.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family YabA PF06156.13 KUM61974.1 - 1.9 9.2 35.2 2.4 8.9 10.1 4.0 2 2 1 3 3 3 0 Initiation control protein YabA Sec34 PF04136.15 KUM61974.1 - 2.1 8.2 26.3 2 8.3 6.6 3.4 2 2 1 3 3 3 0 Sec34-like family Laminin_II PF06009.12 KUM61974.1 - 2.7 8.0 32.9 3.4 7.7 6.3 4.0 2 2 3 5 5 5 0 Laminin Domain II EzrA PF06160.12 KUM61974.1 - 7.8 4.5 42.6 0.75 7.9 22.6 2.5 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA NCD2 PF04905.13 KUM61974.1 - 9.2 6.3 15.8 0.24 11.4 1.1 3.3 2 1 1 3 3 3 0 NAB conserved region 2 (NCD2) ZapB PF06005.12 KUM61974.1 - 9.2 6.8 49.6 0.26 11.7 5.0 5.3 3 1 2 5 5 5 0 Cell division protein ZapB M16C_assoc PF08367.11 KUM61976.1 - 4.2e-74 248.8 0.1 7.2e-74 248.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KUM61976.1 - 3.3e-19 69.6 0.0 9.3e-13 48.6 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KUM61976.1 - 5e-09 36.3 0.0 2.6e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Zn_clus PF00172.18 KUM61977.1 - 1.3e-05 25.2 11.0 2.1e-05 24.6 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_25 PF13649.6 KUM61978.1 - 0.00029 21.5 0.1 0.00054 20.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM61978.1 - 0.011 16.5 0.3 0.024 15.4 0.3 1.5 1 0 0 1 1 1 0 Methyltransferase domain HEPN_AbiU2 PF18734.1 KUM61978.1 - 0.071 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AbiU2 Methyltransf_23 PF13489.6 KUM61978.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF1761 PF08570.10 KUM61980.1 - 8.3e-27 93.9 3.7 9.4e-27 93.7 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) QCR10 PF09796.9 KUM61980.1 - 0.88 9.7 3.8 1.3 9.2 0.6 2.7 2 1 1 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Kinocilin PF15033.6 KUM61980.1 - 2.6 7.7 7.2 5.6 6.6 0.2 2.3 1 1 0 2 2 2 0 Kinocilin protein Methyltransf_16 PF10294.9 KUM61981.1 - 5.3e-48 163.0 0.0 6.5e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase DUF43 PF01861.16 KUM61981.1 - 0.0012 18.2 0.0 0.0016 17.7 0.0 1.1 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_23 PF13489.6 KUM61981.1 - 0.0025 17.7 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM61981.1 - 0.0027 17.5 0.0 0.0035 17.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KUM61981.1 - 0.018 14.6 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DUF2306 PF10067.9 KUM61982.1 - 2.1e-18 67.0 12.9 2.1e-18 67.0 12.9 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) AA_permease PF00324.21 KUM61984.1 - 1.6e-101 340.3 26.6 1.9e-101 340.0 26.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM61984.1 - 8.9e-39 133.5 27.8 1e-38 133.3 27.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM61985.1 - 5.3e-08 31.9 0.5 6.2e-08 31.7 0.5 1.0 1 0 0 1 1 1 1 Amino acid permease SKG6 PF08693.10 KUM61986.1 - 1.2e-07 31.0 1.3 1.2e-07 31.0 0.2 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain BatA PF07584.11 KUM61986.1 - 0.053 13.9 0.0 0.082 13.3 0.0 1.2 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal NICE-1 PF15845.5 KUM61986.1 - 0.072 13.9 2.3 0.072 13.9 2.3 3.1 1 1 3 4 4 4 0 Cysteine-rich C-terminal 1 family DUF202 PF02656.15 KUM61986.1 - 0.12 12.8 0.6 0.24 11.9 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Adeno_E3_CR2 PF02439.15 KUM61986.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Phage_HK97_TLTM PF06120.11 KUM61986.1 - 0.23 10.6 0.0 0.33 10.1 0.0 1.1 1 0 0 1 1 1 0 Tail length tape measure protein SSP160 PF06933.11 KUM61986.1 - 0.42 8.7 10.4 0.53 8.4 10.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF908 PF06012.12 KUM61986.1 - 0.74 9.2 6.5 0.49 9.8 4.7 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) MSA-2c PF12238.8 KUM61986.1 - 2 8.4 8.4 0.06 13.4 2.7 1.4 2 0 0 2 2 2 0 Merozoite surface antigen 2c Deltameth_res PF16020.5 KUM61987.1 - 0.019 14.8 0.7 2.2 8.2 0.1 2.5 1 1 1 2 2 2 0 Deltamethrin resistance Gluconate_2-dh3 PF13618.6 KUM61987.1 - 0.087 13.1 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 DUF2157 PF09925.9 KUM61987.1 - 0.18 11.6 2.5 0.22 11.3 0.8 1.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) JmjC PF02373.22 KUM61988.1 - 7.3e-08 32.8 0.2 2.7e-06 27.8 0.2 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 KUM61988.1 - 6.5e-06 26.3 13.1 6.5e-06 26.3 13.1 2.8 3 0 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 KUM61988.1 - 0.017 14.8 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 Cupin domain UbiA PF01040.18 KUM61989.1 - 5.8e-44 150.3 15.8 7.5e-44 149.9 15.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Flavoprotein PF02441.19 KUM61990.1 - 2.1e-31 108.8 0.0 3.3e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein Ank_2 PF12796.7 KUM61991.1 - 1.3e-25 89.8 0.9 8.3e-09 35.9 0.0 4.9 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM61991.1 - 3.4e-20 72.1 5.6 6.3e-06 26.6 0.0 6.2 4 1 1 6 6 6 4 Ankyrin repeats (many copies) SPX PF03105.19 KUM61991.1 - 7.5e-20 72.2 13.0 5.9e-08 33.0 0.5 3.2 1 1 2 3 3 3 3 SPX domain GDPD PF03009.17 KUM61991.1 - 3.3e-16 59.8 0.1 4.4e-15 56.1 0.0 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_5 PF13857.6 KUM61991.1 - 1e-14 54.4 2.7 0.0074 16.6 0.2 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM61991.1 - 7.7e-14 50.5 6.5 0.0032 17.8 0.0 6.7 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 KUM61991.1 - 8.7e-08 32.3 7.8 0.0062 16.9 0.1 5.7 5 1 0 5 5 5 2 Ankyrin repeat DUF1279 PF06916.13 KUM61992.1 - 4.1e-26 91.4 0.0 5.7e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L3 PF00297.22 KUM61993.1 - 6.4e-18 64.9 5.7 5.9e-16 58.4 2.1 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 Coa1 PF08695.10 KUM61994.1 - 7.1e-44 148.3 0.0 8.9e-44 148.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 OCRE PF17780.1 KUM61995.1 - 0.03 14.3 1.9 0.071 13.1 1.9 1.6 1 0 0 1 1 1 0 OCRE domain SKG6 PF08693.10 KUM61996.1 - 3.4e-13 48.7 3.2 2e-12 46.3 3.2 2.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KUM61996.1 - 4e-05 23.5 0.2 8.3e-05 22.4 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) RIFIN PF02009.16 KUM61996.1 - 0.00027 21.0 8.8 0.00056 19.9 8.8 1.5 1 1 0 1 1 1 1 Rifin TMEM154 PF15102.6 KUM61996.1 - 0.0013 18.7 1.5 0.0013 18.7 1.5 4.1 1 1 2 3 3 1 1 TMEM154 protein family Stevor PF17410.2 KUM61996.1 - 0.0024 17.5 1.9 0.0024 17.5 1.9 1.9 2 0 0 2 2 2 1 Subtelomeric Variable Open Reading frame DUF2207 PF09972.9 KUM61996.1 - 0.033 13.0 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM51 PF15345.6 KUM61996.1 - 0.19 11.6 0.1 0.19 11.6 0.1 2.3 1 1 1 2 2 1 0 Transmembrane protein 51 TFIIA PF03153.13 KUM61996.1 - 0.36 10.8 9.7 0.56 10.1 9.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gemini_mov PF01708.16 KUM61996.1 - 2.1 8.2 0.0 2.1 8.2 0.0 2.8 2 1 0 2 2 1 0 Geminivirus putative movement protein Peptidase_M56 PF05569.11 KUM61996.1 - 2.8 7.0 6.6 0.08 12.1 0.2 1.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 Utp14 PF04615.13 KUM61996.1 - 5.2 5.5 12.3 7.5 5.0 12.3 1.2 1 0 0 1 1 1 0 Utp14 protein Lin-8 PF03353.15 KUM61996.1 - 9.1 5.7 11.5 17 4.8 11.5 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mitofilin PF09731.9 KUM61996.1 - 9.2 5.0 13.4 12 4.5 13.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DIOX_N PF14226.6 KUM61998.1 - 2e-12 47.9 0.0 3.4e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KUM61998.1 - 3.8e-12 46.6 0.0 6.1e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 KUM61999.1 - 1.3e-12 48.0 15.7 3e-05 24.7 0.3 5.1 4 2 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM61999.1 - 3.9e-06 27.1 4.0 0.16 12.2 0.1 3.3 2 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIA PF03153.13 KUM62000.1 - 8.2 6.3 22.4 11 5.9 22.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sugar_tr PF00083.24 KUM62001.1 - 1.5e-104 350.4 16.2 1.9e-104 350.1 16.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM62001.1 - 2.7e-32 112.1 58.6 4.9e-31 107.9 31.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM62001.1 - 7e-07 28.0 3.6 7e-07 28.0 3.6 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KUM62001.1 - 0.00021 19.8 8.5 0.0017 16.9 0.8 2.5 2 0 0 2 2 2 2 Transmembrane secretion effector LacY_symp PF01306.19 KUM62001.1 - 0.00033 19.6 6.9 0.0082 15.0 1.0 2.4 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_1_like PF12832.7 KUM62001.1 - 0.021 13.7 0.0 0.017 14.0 4.5 3.3 1 1 2 3 3 3 0 MFS_1 like family ABC_tran PF00005.27 KUM62004.1 - 1.7e-48 164.6 0.8 7.3e-23 81.6 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KUM62004.1 - 5.5e-20 71.2 6.5 5.5e-20 71.2 6.5 3.5 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 KUM62004.1 - 1.3e-14 54.7 1.5 0.004 17.0 0.1 4.7 5 0 0 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KUM62004.1 - 2.2e-09 37.1 1.6 0.17 11.3 0.0 4.6 5 0 0 5 5 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KUM62004.1 - 2.8e-07 30.9 0.0 0.00067 19.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KUM62004.1 - 1.2e-06 29.0 0.6 0.042 14.2 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KUM62004.1 - 1.5e-06 28.8 15.0 0.017 15.6 0.0 4.9 5 0 0 5 5 5 2 AAA domain AAA_18 PF13238.6 KUM62004.1 - 4.9e-06 27.1 0.3 0.12 12.9 0.1 3.1 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 KUM62004.1 - 7.8e-06 25.9 0.6 0.12 12.5 0.1 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KUM62004.1 - 1.2e-05 25.3 0.0 0.075 12.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KUM62004.1 - 1.4e-05 24.8 0.2 0.19 11.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 KUM62004.1 - 1.9e-05 24.5 1.3 0.41 10.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KUM62004.1 - 4e-05 23.4 0.1 0.0073 16.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KUM62004.1 - 4.9e-05 23.6 4.6 0.017 15.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 KUM62004.1 - 0.00016 21.9 0.1 0.53 10.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KUM62004.1 - 0.00062 19.9 1.7 1.1 9.3 0.0 3.9 4 0 0 4 4 4 1 Dynamin family AAA_15 PF13175.6 KUM62004.1 - 0.00075 19.3 16.1 0.16 11.7 0.0 4.6 4 1 0 4 4 4 2 AAA ATPase domain AAA PF00004.29 KUM62004.1 - 0.0013 19.2 0.0 0.57 10.6 0.1 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sds3 PF08598.11 KUM62004.1 - 0.0018 18.3 3.4 0.0093 16.0 0.1 2.3 2 0 0 2 2 2 1 Sds3-like NACHT PF05729.12 KUM62004.1 - 0.0021 18.0 0.2 0.92 9.4 0.0 2.8 3 0 0 3 3 2 1 NACHT domain RNA_helicase PF00910.22 KUM62004.1 - 0.0025 18.2 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ATP-synt_ab PF00006.25 KUM62004.1 - 0.0028 17.4 0.0 0.28 10.8 0.0 2.5 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 KUM62004.1 - 0.0053 16.1 0.5 1.5 8.0 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin AAA_14 PF13173.6 KUM62004.1 - 0.0065 16.5 0.0 4.4 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KUM62004.1 - 0.0081 16.1 0.4 0.85 9.5 0.0 3.1 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_27 PF13514.6 KUM62004.1 - 0.0087 15.7 0.3 3 7.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.15 KUM62004.1 - 0.0087 16.0 0.3 1.6 8.7 0.1 3.3 3 0 0 3 3 3 1 NTPase MeaB PF03308.16 KUM62004.1 - 0.01 14.8 2.5 2.4 7.1 0.0 2.7 3 0 0 3 3 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 KUM62004.1 - 0.012 15.6 0.1 4.3 7.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KUM62004.1 - 0.016 14.8 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region SRP54 PF00448.22 KUM62004.1 - 0.024 14.3 0.7 0.96 9.0 0.0 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Roc PF08477.13 KUM62004.1 - 0.027 14.7 0.0 12 6.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_17 PF13207.6 KUM62004.1 - 0.039 14.4 0.6 13 6.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 KUM62004.1 - 0.043 13.4 2.4 1 8.9 0.2 2.9 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KUM62004.1 - 0.044 13.0 0.0 6.5 5.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain TsaE PF02367.17 KUM62004.1 - 0.068 13.2 0.0 9.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 KUM62004.1 - 0.079 12.9 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B dNK PF01712.19 KUM62004.1 - 0.084 12.7 0.1 0.96 9.3 0.1 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase Arf PF00025.21 KUM62004.1 - 0.13 11.7 0.1 1.6 8.1 0.1 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family GP57 PF17594.2 KUM62004.1 - 0.16 11.7 1.0 1.9 8.3 0.5 2.6 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 PRK PF00485.18 KUM62004.1 - 0.37 10.5 2.0 0.67 9.7 0.0 2.4 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 KUM62004.1 - 2.1 8.4 0.0 2.1 8.4 0.0 4.2 6 0 0 6 6 5 0 Helicase HerA, central domain MFS_1 PF07690.16 KUM62005.1 - 5e-15 55.3 69.7 2.9e-14 52.7 64.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM62005.1 - 0.0015 17.1 24.4 0.0022 16.5 24.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Esterase PF00756.20 KUM62006.1 - 2.4e-15 56.9 0.0 3.3e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KUM62006.1 - 1.4e-05 24.7 0.0 2.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KUM62006.1 - 1.6e-05 24.3 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KUM62006.1 - 0.0028 18.3 0.5 0.0072 16.9 0.1 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF2920 PF11144.8 KUM62006.1 - 0.082 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) CTP_transf_like PF01467.26 KUM62007.1 - 3.1e-23 82.5 0.0 2.4e-20 73.2 0.0 2.6 2 1 1 3 3 3 2 Cytidylyltransferase-like Glutaredoxin PF00462.24 KUM62008.1 - 1.2e-14 54.3 0.0 2.1e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin HNH_2 PF13391.6 KUM62009.1 - 0.017 15.3 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease AhpC-TSA PF00578.21 KUM62010.1 - 4.1e-22 78.4 0.0 5.9e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KUM62010.1 - 8.3e-14 51.5 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KUM62010.1 - 0.026 14.6 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme PRELI PF04707.14 KUM62011.1 - 4.1e-43 146.9 0.2 4.8e-43 146.7 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family BRCA-2_OB3 PF09104.10 KUM62011.1 - 0.052 13.2 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Mpp10 PF04006.12 KUM62013.1 - 7.3e-107 358.3 47.7 1.3e-105 354.2 47.7 2.0 1 1 0 1 1 1 1 Mpp10 protein adh_short_C2 PF13561.6 KUM62014.1 - 1.3e-58 198.3 0.0 1.7e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM62014.1 - 1.6e-44 151.8 0.0 1.9e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM62014.1 - 3.4e-12 46.6 0.0 4.8e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 KR domain PALP PF00291.25 KUM62014.1 - 0.0062 16.0 0.0 0.0094 15.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NusB PF01029.18 KUM62014.1 - 0.13 12.5 0.1 0.21 11.8 0.1 1.2 1 0 0 1 1 1 0 NusB family FMO-like PF00743.19 KUM62017.1 - 3.4e-18 65.4 0.0 2.9e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KUM62017.1 - 1.5e-14 54.0 0.0 1.3e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM62017.1 - 5.3e-12 45.5 0.0 4.9e-09 35.8 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KUM62017.1 - 4.6e-11 42.5 0.0 1.9e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM62017.1 - 2.5e-08 34.0 0.1 2.1e-07 31.1 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM62017.1 - 0.00014 21.6 2.2 0.24 10.9 0.7 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KUM62017.1 - 0.0021 17.2 0.0 0.004 16.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KUM62017.1 - 0.0061 17.1 0.2 5.5 7.6 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM62017.1 - 0.0068 16.4 0.2 4.7 7.2 0.7 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KUM62017.1 - 0.012 14.9 0.2 0.098 11.9 0.0 2.3 3 0 0 3 3 3 0 Thi4 family Shikimate_DH PF01488.20 KUM62017.1 - 0.037 14.1 0.0 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KUM62017.1 - 0.063 13.7 0.0 0.37 11.3 0.0 2.2 3 0 0 3 3 3 0 Putative NAD(P)-binding HI0933_like PF03486.14 KUM62017.1 - 0.16 10.6 0.2 0.43 9.2 0.2 1.7 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 KUM62017.1 - 0.17 11.2 0.0 0.35 10.2 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans PF04082.18 KUM62018.1 - 3.9e-14 52.3 0.3 6.6e-14 51.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM62018.1 - 1.8e-05 24.8 10.2 4e-05 23.6 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Elf1 PF05129.13 KUM62018.1 - 0.2 11.7 2.9 0.42 10.7 2.9 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like ADH_zinc_N PF00107.26 KUM62019.1 - 9.9e-13 48.2 0.1 1.5e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM62019.1 - 0.0068 17.4 0.1 0.014 16.4 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase CpcD PF01383.21 KUM62019.1 - 0.022 15.0 0.1 0.047 14.0 0.1 1.5 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain adh_short_C2 PF13561.6 KUM62020.1 - 2e-57 194.5 0.5 2.2e-57 194.3 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM62020.1 - 1.5e-46 158.4 1.0 1.8e-46 158.1 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Abhydrolase_3 PF07859.13 KUM62021.1 - 2.4e-45 155.0 0.0 3e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KUM62021.1 - 7.1e-10 38.4 4.0 9.6e-10 37.9 1.7 2.1 2 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KUM62021.1 - 1.8e-05 25.5 0.5 2.8e-05 24.8 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KUM62021.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family EnY2 PF10163.9 KUM62022.1 - 4.9e-06 26.8 0.0 8.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 SAM_2 PF07647.17 KUM62023.1 - 3.2e-14 52.8 0.0 5.8e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KUM62023.1 - 4e-13 49.8 0.0 7.6e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.30 KUM62023.1 - 6.1e-13 49.0 0.1 1.2e-12 48.1 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_4 PF18017.1 KUM62023.1 - 0.076 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Sugar_tr PF00083.24 KUM62024.1 - 3.6e-101 339.3 22.7 4.2e-101 339.0 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM62024.1 - 4.2e-39 134.5 40.3 7.9e-34 117.1 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SPT_ssu-like PF11779.8 KUM62024.1 - 0.0067 16.0 1.1 0.025 14.2 1.1 2.0 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like TRI12 PF06609.13 KUM62024.1 - 0.024 13.1 6.0 0.33 9.3 1.6 2.3 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF5088 PF17008.5 KUM62024.1 - 0.047 13.4 0.1 0.084 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5088) ADH_N PF08240.12 KUM62025.1 - 4e-31 107.1 1.5 8.3e-31 106.1 1.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM62025.1 - 4.8e-20 71.9 0.1 8e-20 71.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KUM62025.1 - 8.6e-11 41.7 0.0 1.4e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KUM62025.1 - 0.00025 22.1 0.0 0.0012 19.9 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KUM62025.1 - 0.001 18.4 0.6 0.0017 17.7 0.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KUM62025.1 - 0.0069 15.7 0.0 0.0097 15.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KUM62025.1 - 0.06 12.9 0.1 0.095 12.3 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fungal_trans PF04082.18 KUM62026.1 - 3.7e-21 75.3 0.0 1e-20 73.9 0.0 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain CAF1C_H4-bd PF12265.8 KUM62027.1 - 5.3e-17 61.8 0.2 5.9e-16 58.5 0.0 2.7 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KUM62027.1 - 9.9e-15 54.7 8.7 1.5e-06 28.8 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM62027.1 - 1.5e-08 34.8 2.1 0.00066 19.9 0.2 3.3 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Transglut_core PF01841.19 KUM62028.1 - 1.8e-12 47.7 0.0 3.6e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 KUM62028.1 - 0.065 12.8 0.0 0.82 9.2 0.0 2.4 1 1 0 1 1 1 0 Transglutaminase-like domain Ras PF00071.22 KUM62029.1 - 5e-31 107.5 0.2 6.8e-31 107.0 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM62029.1 - 1.6e-23 83.2 0.1 2.9e-23 82.4 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM62029.1 - 1.4e-06 27.9 0.1 2.1e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KUM62029.1 - 0.00028 20.3 0.2 0.00041 19.8 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KUM62029.1 - 0.011 14.6 0.1 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 KUM62029.1 - 0.031 13.4 1.1 0.65 9.1 0.1 2.4 1 1 1 2 2 2 0 G-protein alpha subunit Ribosomal_L37ae PF01780.19 KUM62030.1 - 1.6e-40 137.0 9.6 1.8e-40 136.9 9.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KUM62030.1 - 0.0036 17.4 1.5 0.005 16.9 1.5 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF1451 PF07295.11 KUM62030.1 - 0.011 15.7 0.8 0.016 15.3 0.8 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Zn_Tnp_IS1595 PF12760.7 KUM62030.1 - 0.033 14.2 1.7 0.055 13.5 1.7 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.10 KUM62030.1 - 0.033 13.9 2.3 1.8 8.3 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-BED PF02892.15 KUM62030.1 - 0.11 12.5 3.5 1.3 9.1 0.6 2.2 1 1 1 2 2 2 0 BED zinc finger Sacchrp_dh_NADP PF03435.18 KUM62031.1 - 1.2e-17 64.3 0.0 1.8e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Abhydrolase_1 PF00561.20 KUM62032.1 - 4.4e-10 39.6 0.4 5.4e-05 23.0 0.0 2.7 2 1 1 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM62032.1 - 1.4e-05 24.5 0.0 0.014 14.6 0.0 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KUM62032.1 - 2.9e-05 24.8 2.2 0.0026 18.4 2.2 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KUM62032.1 - 0.04 14.0 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein PHF5 PF03660.14 KUM62033.1 - 8.2e-53 177.0 9.7 9.1e-53 176.9 9.7 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KUM62033.1 - 0.13 10.2 5.2 0.13 10.1 5.2 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KUM62033.1 - 2 8.5 15.5 5.7 7.0 2.0 3.0 1 1 1 2 2 2 0 Double zinc ribbon Pinin_SDK_memA PF04696.13 KUM62034.1 - 1.4e-30 106.0 11.0 1.4e-30 106.0 11.0 3.0 3 0 0 3 3 3 1 pinin/SDK/memA/ protein conserved region RSB_motif PF16294.5 KUM62034.1 - 0.0056 16.9 9.3 0.0056 16.9 9.3 3.8 2 2 1 3 3 3 1 RNSP1-SAP18 binding (RSB) motif Cofilin_ADF PF00241.20 KUM62035.1 - 1.2e-24 86.4 0.0 1.2e-13 50.9 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein ORC5_C PF14630.6 KUM62036.1 - 0.0093 15.5 0.4 0.0093 15.5 0.4 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus CDC45 PF02724.14 KUM62036.1 - 0.041 12.2 0.4 0.032 12.5 0.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Cnd1_N PF12922.7 KUM62036.1 - 0.094 12.6 3.5 0.13 12.1 3.5 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Pex26 PF07163.12 KUM62036.1 - 0.4 9.9 2.0 0.46 9.7 2.0 1.1 1 0 0 1 1 1 0 Pex26 protein LYRIC PF15686.5 KUM62036.1 - 1 8.8 12.4 1.1 8.7 12.4 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family AP3D1 PF06375.11 KUM62036.1 - 1.1 9.5 20.2 1.3 9.2 20.2 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Connexin PF00029.19 KUM62036.1 - 1.4 8.6 7.3 1.9 8.2 7.3 1.4 1 1 0 1 1 1 0 Connexin Tox-WTIP PF15654.6 KUM62036.1 - 2 8.9 3.7 10 6.6 0.1 2.1 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif DUF1168 PF06658.12 KUM62036.1 - 2.4 7.9 22.1 3 7.6 22.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Jak1_Phl PF17887.1 KUM62036.1 - 2.8 7.9 7.9 3.8 7.5 7.9 1.2 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain SR-25 PF10500.9 KUM62036.1 - 3.3 7.3 26.7 4 7.0 26.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PHD PF00628.29 KUM62037.1 - 3.2e-10 39.8 13.1 5.3e-10 39.0 4.5 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 KUM62037.1 - 5.8e-09 36.1 1.1 5.8e-09 36.1 1.1 3.2 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 KUM62037.1 - 9.5e-07 29.0 0.7 9.5e-07 29.0 0.7 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KUM62037.1 - 2.1e-06 27.5 0.9 2.1e-06 27.5 0.9 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KUM62037.1 - 3.5e-06 26.8 1.0 3.5e-06 26.8 1.0 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KUM62037.1 - 5.3e-06 26.2 1.9 5.3e-06 26.2 1.9 2.4 4 0 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KUM62037.1 - 1.8e-05 24.6 1.1 1.8e-05 24.6 1.1 2.5 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KUM62037.1 - 5.3e-05 23.0 1.0 5.3e-05 23.0 1.0 3.2 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 KUM62037.1 - 0.00035 20.1 1.8 0.00035 20.1 1.8 1.9 2 0 0 2 2 1 1 PHD-finger zf-RING_UBOX PF13445.6 KUM62037.1 - 0.00093 19.2 0.8 0.00093 19.2 0.8 3.2 3 1 1 4 4 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KUM62037.1 - 0.0046 16.5 0.8 0.0046 16.5 0.8 2.3 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KUM62037.1 - 0.0049 16.9 0.1 0.0049 16.9 0.1 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2HC_2 PF13913.6 KUM62037.1 - 0.012 15.5 0.8 0.36 10.8 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type UvrA_inter PF17760.1 KUM62037.1 - 0.026 14.6 0.9 0.047 13.8 0.9 1.3 1 0 0 1 1 1 0 UvrA interaction domain zf-RING_11 PF17123.5 KUM62037.1 - 0.6 9.9 0.0 0.6 9.9 0.0 3.2 4 0 0 4 4 4 0 RING-like zinc finger Zf_RING PF16744.5 KUM62037.1 - 0.75 10.0 7.6 0.63 10.2 0.9 2.9 2 1 0 2 2 2 0 KIAA1045 RING finger zf-RING_4 PF14570.6 KUM62037.1 - 2.1 8.2 5.0 0.54 10.1 0.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_9 PF13901.6 KUM62037.1 - 4.7 7.1 5.8 7.5 6.5 0.3 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon DZR PF12773.7 KUM62037.1 - 5.7 7.0 7.1 8.8e+02 0.0 7.1 3.0 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.6 KUM62037.1 - 7.1 6.7 12.4 0.28 11.1 1.3 3.0 4 0 0 4 4 3 0 Prokaryotic RING finger family 1 TRAM_LAG1_CLN8 PF03798.16 KUM62040.1 - 2.9e-38 131.6 19.5 2.9e-38 131.6 19.5 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KUM62040.1 - 3.3e-24 84.3 0.0 8.9e-24 82.9 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein Sulfatase PF00884.23 KUM62042.1 - 6.1e-24 85.0 2.2 1.3e-23 83.9 2.2 1.5 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KUM62042.1 - 1.8e-05 24.5 0.5 2.9e-05 23.9 0.5 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sugar_tr PF00083.24 KUM62043.1 - 4.1e-110 368.8 20.3 5.2e-110 368.4 20.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM62043.1 - 9.7e-25 87.2 31.6 5.3e-23 81.5 19.2 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF4758 PF15950.5 KUM62043.1 - 0.045 14.1 0.1 0.075 13.4 0.1 1.3 1 0 0 1 1 1 0 Putative sperm flagellar membrane protein DUF2530 PF10745.9 KUM62043.1 - 0.9 9.8 6.6 0.81 10.0 0.9 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Polysacc_deac_1 PF01522.21 KUM62044.1 - 1.3e-31 109.0 0.0 2.4e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KUM62044.1 - 1.9e-05 25.1 46.7 6.7e-05 23.3 15.2 2.9 2 1 0 2 2 2 2 Chitin recognition protein Glyco_hydro_57 PF03065.15 KUM62044.1 - 0.02 14.1 0.0 0.04 13.1 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 Coilin_N PF15862.5 KUM62045.1 - 0.34 10.7 2.9 2.2 8.1 0.0 2.6 1 1 1 2 2 2 0 Coilin N-terminus HEAT PF02985.22 KUM62047.1 - 0.0016 18.5 0.1 1.5 9.3 0.0 3.7 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 KUM62047.1 - 0.0017 18.7 0.3 0.22 11.9 0.1 3.1 3 1 0 3 3 3 1 HEAT repeats RTP1_C1 PF10363.9 KUM62047.1 - 0.0051 17.0 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KUM62047.1 - 0.012 14.2 0.5 0.52 8.8 0.1 2.6 2 1 0 2 2 2 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KUM62047.1 - 0.013 16.1 0.0 0.039 14.5 0.0 1.8 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region Cnd3 PF12719.7 KUM62047.1 - 0.013 14.7 0.1 0.032 13.4 0.0 1.6 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain DRIM PF07539.12 KUM62047.1 - 0.13 10.5 2.0 2 6.6 0.1 2.1 1 1 1 2 2 2 0 Down-regulated in metastasis His_biosynth PF00977.21 KUM62048.1 - 3.6e-32 111.7 0.0 4.8e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF4602 PF15375.6 KUM62049.1 - 2.2e-13 50.7 16.6 4.4e-13 49.7 16.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) DUF2310 PF10071.9 KUM62050.1 - 0.021 14.1 0.1 0.026 13.8 0.1 1.1 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) SDA1 PF05285.12 KUM62050.1 - 0.99 8.8 15.9 1.1 8.6 15.9 1.0 1 0 0 1 1 1 0 SDA1 CoA_binding PF02629.19 KUM62051.1 - 8.1e-26 90.5 1.7 3e-25 88.7 0.5 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KUM62051.1 - 7.5e-22 77.8 0.1 1.3e-21 77.1 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KUM62051.1 - 4.8e-07 29.6 0.0 9.6e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KUM62051.1 - 0.0044 17.5 0.1 0.011 16.3 0.0 1.7 2 0 0 2 2 2 1 CoA binding domain Radical_SAM_C PF16199.5 KUM62052.1 - 1.5e-32 111.5 0.1 4.2e-32 110.0 0.0 1.8 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KUM62052.1 - 4.2e-20 72.8 0.1 2.2e-19 70.4 0.0 2.2 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KUM62052.1 - 3.4e-11 43.4 0.1 6.4e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KUM62052.1 - 1.5e-05 24.9 0.1 6.8e-05 22.8 0.0 2.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Topoisom_bac PF01131.20 KUM62052.1 - 0.3 10.0 0.6 0.44 9.5 0.6 1.2 1 0 0 1 1 1 0 DNA topoisomerase Yip1 PF04893.17 KUM62053.1 - 0.018 14.8 0.3 0.025 14.3 0.3 1.2 1 0 0 1 1 1 0 Yip1 domain MRVI1 PF05781.12 KUM62053.1 - 0.12 11.1 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 MRVI1 protein Isochorismatase PF00857.20 KUM62054.1 - 1.8e-19 70.6 0.0 3e-19 69.9 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family PuR_N PF09182.10 KUM62054.1 - 0.15 12.0 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal NAD_binding_4 PF07993.12 KUM62056.1 - 1.3e-53 181.8 0.0 1.7e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KUM62056.1 - 1.2e-24 86.7 0.0 2.2e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KUM62056.1 - 5.5e-11 42.7 0.1 1.1e-10 41.7 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KUM62056.1 - 8.7e-08 31.9 0.0 2.3e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 KUM62056.1 - 6.3e-06 27.1 0.0 1.6e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 KUM62056.1 - 0.0014 17.7 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KUM62056.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Phage_int_SAM_5 PF13102.6 KUM62056.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Phage integrase SAM-like domain Myb_DNA-binding PF00249.31 KUM62057.1 - 0.048 13.9 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain AAA_8 PF12780.7 KUM62057.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Phage_tail_L PF05100.12 KUM62057.1 - 0.12 11.6 0.6 4.7 6.5 0.2 2.2 2 0 0 2 2 2 0 Phage minor tail protein L SWIRM PF04433.17 KUM62058.1 - 1e-31 109.1 0.1 3e-31 107.6 0.1 1.8 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KUM62058.1 - 3.6e-31 106.9 12.5 9.2e-31 105.7 12.5 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KUM62058.1 - 7.1e-09 35.7 0.1 1.8e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KUM62058.1 - 9.3e-06 25.8 0.0 2.3e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Mei5 PF10376.9 KUM62058.1 - 0.12 12.3 4.8 0.23 11.3 4.8 1.4 1 0 0 1 1 1 0 Double-strand recombination repair protein DUF883 PF05957.13 KUM62058.1 - 0.18 12.4 9.6 0.15 12.6 3.7 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Myb_DNA-bind_7 PF15963.5 KUM62058.1 - 0.22 11.5 1.8 1.8 8.5 0.0 2.8 2 0 0 2 2 2 0 Myb DNA-binding like AAA_9 PF12781.7 KUM62058.1 - 0.25 10.4 2.4 0.47 9.6 2.4 1.3 1 0 0 1 1 1 0 ATP-binding dynein motor region ZZ PF00569.17 KUM62058.1 - 1.5 8.7 5.9 13 5.7 5.9 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type ABC_tran PF00005.27 KUM62059.1 - 6e-46 156.4 0.1 2.2e-23 83.3 0.0 3.8 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 KUM62059.1 - 4.1e-29 100.5 3.8 1.3e-28 98.9 3.8 2.0 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 KUM62059.1 - 9.3e-15 55.2 0.0 0.0023 17.8 0.0 4.5 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KUM62059.1 - 6e-13 48.7 0.1 0.00019 20.9 0.0 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KUM62059.1 - 1.6e-09 38.6 0.0 0.0019 18.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KUM62059.1 - 4.8e-08 32.6 0.2 0.0095 15.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KUM62059.1 - 9.3e-08 32.5 0.0 0.013 15.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KUM62059.1 - 6.9e-06 26.1 0.0 0.0045 17.1 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KUM62059.1 - 7.4e-06 25.8 0.0 0.16 11.7 0.0 2.9 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KUM62059.1 - 1.2e-05 25.3 0.0 0.012 15.5 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KUM62059.1 - 1.2e-05 25.8 0.1 0.12 12.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KUM62059.1 - 1.6e-05 25.2 0.0 0.031 14.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 KUM62059.1 - 1.7e-05 25.3 0.2 0.39 11.1 0.0 3.5 4 0 0 4 4 2 2 AAA ATPase domain RNA_helicase PF00910.22 KUM62059.1 - 0.0001 22.6 0.0 0.51 10.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase DUF87 PF01935.17 KUM62059.1 - 0.00011 22.4 0.5 0.064 13.3 0.2 3.1 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_14 PF13173.6 KUM62059.1 - 0.00018 21.5 0.0 0.35 10.9 0.0 3.4 4 0 0 4 4 2 1 AAA domain NACHT PF05729.12 KUM62059.1 - 0.00021 21.3 0.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 KUM62059.1 - 0.00027 21.3 0.0 0.21 12.0 0.0 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KUM62059.1 - 0.00032 20.5 0.0 1.2 8.8 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 KUM62059.1 - 0.00039 20.5 0.0 0.002 18.2 0.0 2.3 2 0 0 2 2 2 1 Dynamin family G-alpha PF00503.20 KUM62059.1 - 0.0006 19.1 0.0 0.79 8.8 0.0 2.6 2 0 0 2 2 2 2 G-protein alpha subunit NB-ARC PF00931.22 KUM62059.1 - 0.0013 18.0 0.1 0.029 13.6 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain cobW PF02492.19 KUM62059.1 - 0.0014 18.2 0.7 0.72 9.4 0.0 3.7 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KUM62059.1 - 0.0015 18.7 0.0 3.2 7.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KUM62059.1 - 0.0016 18.1 0.9 0.45 10.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KUM62059.1 - 0.0017 18.2 0.0 1.5 8.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KUM62059.1 - 0.0018 18.1 0.1 1.1 8.9 0.0 3.5 4 0 0 4 4 3 1 AAA domain MeaB PF03308.16 KUM62059.1 - 0.002 17.2 0.1 0.96 8.4 0.1 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_13 PF13166.6 KUM62059.1 - 0.0028 16.4 1.7 0.37 9.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 KUM62059.1 - 0.0072 15.9 0.0 4.4 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KUM62059.1 - 0.008 16.4 0.0 2.1 8.6 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Roc PF08477.13 KUM62059.1 - 0.0095 16.2 0.0 5.5 7.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KUM62059.1 - 0.019 14.7 0.0 6.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 KUM62059.1 - 0.029 13.7 0.4 3.2 7.0 0.0 3.0 3 0 0 3 3 3 0 Septin MukB PF04310.12 KUM62059.1 - 0.029 14.2 0.0 6.1 6.6 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal ATP-synt_ab PF00006.25 KUM62059.1 - 0.032 13.9 0.0 3.1 7.4 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 KUM62059.1 - 0.044 13.3 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KUM62059.1 - 0.047 13.6 0.0 0.75 9.7 0.0 2.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KUM62059.1 - 0.049 13.6 0.0 7.4 6.6 0.0 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IclR PF01614.18 KUM62059.1 - 0.071 12.9 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 Bacterial transcriptional regulator Arf PF00025.21 KUM62059.1 - 0.071 12.6 0.1 7 6.1 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family RPN6_C_helix PF18503.1 KUM62059.1 - 0.096 12.4 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain FtsK_SpoIIIE PF01580.18 KUM62059.1 - 0.1 11.9 0.5 0.51 9.6 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family PRK PF00485.18 KUM62059.1 - 0.11 12.3 0.0 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family CLP1_P PF16575.5 KUM62059.1 - 0.12 12.1 0.6 3.8 7.3 0.0 2.9 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ResIII PF04851.15 KUM62060.1 - 4.4e-24 85.4 0.0 2.9e-23 82.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KUM62060.1 - 1.9e-12 47.5 0.1 2.2e-11 44.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KUM62060.1 - 8.1e-10 38.7 0.0 1.8e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KUM62060.1 - 1.8e-06 27.8 0.0 5.1e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 KUM62060.1 - 0.0004 19.7 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Gly_transf_sug PF04488.15 KUM62061.1 - 3.5e-11 43.6 0.2 6.5e-11 42.7 0.2 1.5 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KUM62061.1 - 0.012 15.0 0.1 0.035 13.4 0.0 1.6 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain SnoaL_4 PF13577.6 KUM62062.1 - 5.9e-20 71.7 0.0 6.8e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain DUF5525 PF17663.1 KUM62063.1 - 0.43 8.6 13.6 0.009 14.1 6.7 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5525) MFS_1 PF07690.16 KUM62064.1 - 9.8e-24 83.9 52.5 9.8e-24 83.9 52.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 KUM62064.1 - 0.48 10.3 0.0 0.48 10.3 0.0 4.8 8 0 0 8 8 8 0 Lipopolysaccharide assembly protein A domain PGAP1 PF07819.13 KUM62066.1 - 6.8e-89 297.6 0.0 1.1e-88 296.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KUM62066.1 - 6.6e-07 30.2 0.4 1.7e-06 28.8 0.4 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM62066.1 - 0.00033 20.4 0.5 0.0012 18.6 0.5 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 KUM62066.1 - 0.00083 19.3 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Esterase PF00756.20 KUM62066.1 - 0.0095 15.6 0.0 0.038 13.6 0.0 1.8 2 0 0 2 2 2 1 Putative esterase LCAT PF02450.15 KUM62066.1 - 0.011 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 KUM62066.1 - 0.012 14.9 0.0 0.028 13.7 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF676 PF05057.14 KUM62066.1 - 0.052 13.0 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Methyltransf_10 PF05971.12 KUM62067.1 - 5.4e-53 180.3 0.4 1.2e-30 107.0 0.1 2.5 2 1 0 2 2 2 2 RNA methyltransferase MTS PF05175.14 KUM62067.1 - 0.0005 19.7 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KUM62067.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 KUM62067.1 - 0.2 11.2 0.0 0.42 10.2 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MFS_1 PF07690.16 KUM62068.1 - 7.1e-42 143.6 39.7 1.6e-38 132.6 20.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM62068.1 - 1.3e-08 34.1 11.7 1.3e-08 34.1 11.7 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KUM62068.1 - 0.019 13.3 9.4 0.59 8.4 0.1 3.0 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Cellulase PF00150.18 KUM62069.1 - 2e-31 109.5 2.5 8.8e-31 107.4 1.3 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) TPR_2 PF07719.17 KUM62070.1 - 0.001 19.0 8.3 0.02 15.0 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KUM62070.1 - 0.0021 17.8 1.2 0.29 11.0 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KUM62070.1 - 0.069 13.2 0.6 2.6 8.3 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KUM62070.1 - 0.08 13.4 0.0 7.6 7.2 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KUM62070.1 - 0.18 11.5 0.1 20 4.9 0.0 3.2 2 1 1 3 3 3 0 TPR repeat Complex1_LYR PF05347.15 KUM62071.1 - 0.0018 18.3 0.1 0.0049 16.9 0.1 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Ank_4 PF13637.6 KUM62072.1 - 2.2e-10 40.8 0.2 2.7e-07 31.0 0.1 3.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KUM62072.1 - 0.00011 22.7 0.1 0.06 13.9 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KUM62072.1 - 0.0019 18.5 0.4 0.11 12.9 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM62072.1 - 0.0019 18.5 0.9 1 10.2 0.1 3.7 3 0 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.13 KUM62072.1 - 0.0067 16.3 0.4 0.045 13.6 0.4 2.2 1 1 0 1 1 1 1 KilA-N domain Baculo_PEP_C PF04513.12 KUM62072.1 - 0.14 12.1 0.0 0.4 10.7 0.0 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sugar_tr PF00083.24 KUM62073.1 - 3.7e-36 125.0 20.0 1.9e-35 122.6 20.0 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM62073.1 - 8.2e-29 100.6 26.9 8.2e-29 100.6 26.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_9_N PF15420.6 KUM62073.1 - 0.63 10.0 7.3 0.14 12.2 1.7 2.4 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus Rick_17kDa_Anti PF05433.15 KUM62074.1 - 0.00017 21.4 13.6 0.00017 21.4 13.6 2.0 2 0 0 2 2 2 1 Glycine zipper 2TM domain Dehydrin PF00257.19 KUM62074.1 - 0.033 14.7 18.1 0.07 13.7 17.8 1.8 1 1 0 1 1 1 0 Dehydrin SR-25 PF10500.9 KUM62074.1 - 0.052 13.1 13.1 0.085 12.5 13.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 KUM62074.1 - 0.11 12.7 23.0 0.2 11.9 23.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) MarC PF01914.17 KUM62074.1 - 0.13 11.6 0.1 0.18 11.2 0.1 1.1 1 0 0 1 1 1 0 MarC family integral membrane protein SNARE_assoc PF09335.11 KUM62074.1 - 0.13 12.7 0.0 0.19 12.2 0.0 1.1 1 0 0 1 1 1 0 SNARE associated Golgi protein AP3D1 PF06375.11 KUM62074.1 - 2.4 8.4 15.6 3.5 7.8 15.6 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF533 PF04391.12 KUM62074.1 - 4 7.0 10.5 0.086 12.4 3.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF533) TFIIF_alpha PF05793.12 KUM62074.1 - 5.5 5.5 16.1 6.9 5.1 16.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) His_Phos_2 PF00328.22 KUM62075.1 - 7.4e-39 134.2 0.0 1e-38 133.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Tcp11 PF05794.13 KUM62077.1 - 4.2e-111 372.2 0.0 4.2e-111 372.2 0.0 2.7 3 1 0 3 3 3 1 T-complex protein 11 Sugar_tr PF00083.24 KUM62078.1 - 0.0041 16.0 0.0 0.0048 15.8 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Peptidase_S10 PF00450.22 KUM62079.1 - 5.3e-112 375.3 0.0 6.4e-112 375.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase WD40 PF00400.32 KUM62080.1 - 9.5e-29 99.1 19.8 9.6e-07 29.4 0.1 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM62080.1 - 1.9e-11 44.1 2.0 0.05 13.9 0.0 5.0 3 2 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Endosulfine PF04667.17 KUM62081.1 - 7e-29 99.8 0.0 1.1e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.13 KUM62082.1 - 8.5e-83 276.8 0.0 1e-82 276.6 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase bPH_5 PF10882.8 KUM62082.1 - 0.0035 17.4 0.0 1.8 8.7 0.0 2.3 2 0 0 2 2 2 2 Bacterial PH domain UPF0160 PF03690.13 KUM62083.1 - 1.1e-126 422.9 0.0 1.2e-126 422.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ICE2 PF08426.10 KUM62084.1 - 1.9e-150 501.5 9.8 2.2e-150 501.3 9.8 1.0 1 0 0 1 1 1 1 ICE2 MHYT PF03707.16 KUM62084.1 - 1.1 9.5 0.0 1.1 9.5 0.0 4.5 4 1 0 4 4 4 0 Bacterial signalling protein N terminal repeat zinc_ribbon_6 PF14599.6 KUM62085.1 - 2.4e-24 85.1 0.3 3.8e-24 84.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-ribbon Zn_ribbon_recom PF13408.6 KUM62085.1 - 0.052 14.1 1.0 0.11 13.0 1.0 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain HypA PF01155.19 KUM62085.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_pol_phi PF04931.13 KUM62085.1 - 0.96 7.5 6.0 1.2 7.1 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KUM62085.1 - 7.1 5.9 7.5 7.2 5.8 5.3 1.8 2 0 0 2 2 2 0 NOA36 protein CENP-B_dimeris PF09026.10 KUM62085.1 - 9.4 6.7 12.1 20 5.6 12.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-CHY PF05495.12 KUM62086.1 - 3.1e-20 72.4 23.6 3.1e-20 72.4 23.6 2.0 2 0 0 2 2 2 1 CHY zinc finger DUF3336 PF11815.8 KUM62087.1 - 1.5e-37 128.4 0.0 2.8e-35 121.0 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3336) Patatin PF01734.22 KUM62087.1 - 1.5e-14 54.7 0.5 3.8e-14 53.4 0.1 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase TAFH PF07531.14 KUM62087.1 - 0.043 13.9 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 NHR1 homology to TAF Ribosomal_L6 PF00347.23 KUM62088.1 - 2.2e-21 76.3 2.8 1.1e-09 38.9 1.1 2.5 2 0 0 2 2 2 2 Ribosomal protein L6 Glutaredoxin PF00462.24 KUM62088.1 - 1.4e-05 25.2 0.0 5.3e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 Glutaredoxin BSP_II PF05432.11 KUM62088.1 - 0.063 13.0 10.1 0.095 12.4 10.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) MPP6 PF10175.9 KUM62088.1 - 0.076 13.5 3.6 0.12 12.9 3.6 1.3 1 0 0 1 1 1 0 M-phase phosphoprotein 6 LAP1C PF05609.12 KUM62088.1 - 0.2 10.7 1.9 0.26 10.3 1.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Smg8_Smg9 PF10220.9 KUM62088.1 - 1.3 7.2 3.9 1.8 6.8 3.9 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Abhydrolase_1 PF00561.20 KUM62089.1 - 2.8e-09 37.0 0.0 7.5e-09 35.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KUM62089.1 - 5.2e-09 37.0 3.9 3e-08 34.5 1.2 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM62089.1 - 4.6e-08 32.6 0.0 2.5e-06 26.9 0.0 2.7 3 0 0 3 3 3 1 Serine aminopeptidase, S33 NFACT-R_1 PF05670.13 KUM62090.1 - 3.3e-38 130.7 0.0 5.7e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain TBCC PF07986.12 KUM62090.1 - 0.044 13.5 0.0 0.41 10.4 0.0 2.3 2 1 1 3 3 3 0 Tubulin binding cofactor C ART-PolyVal PF18760.1 KUM62090.1 - 1.1 10.3 7.5 1.6 9.8 7.1 1.5 1 1 0 1 1 1 0 ADP-Ribosyltransferase in polyvalent proteins Paramyxo_ncap PF00973.19 KUM62090.1 - 3.2 6.6 6.5 3.9 6.3 6.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Pox_P35 PF03213.14 KUM62090.1 - 3.4 6.8 9.3 1.4 8.1 0.1 2.1 1 1 1 2 2 2 0 Poxvirus P35 protein F-box-like PF12937.7 KUM62092.1 - 0.11 12.4 0.6 0.23 11.4 0.1 1.7 2 0 0 2 2 2 0 F-box-like PXA PF02194.15 KUM62093.1 - 6.7e-51 172.8 2.7 1.2e-50 172.0 0.4 2.7 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 KUM62093.1 - 1.1e-26 93.6 0.0 1e-25 90.4 0.0 2.8 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 KUM62093.1 - 1.5e-21 76.5 0.6 3.2e-21 75.4 0.6 1.6 1 0 0 1 1 1 1 PX domain RGS PF00615.19 KUM62093.1 - 5.6e-11 42.7 0.0 1.8e-10 41.1 0.0 2.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain WD40 PF00400.32 KUM62094.1 - 3.4e-17 62.5 2.7 0.011 16.6 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM62094.1 - 5e-07 29.9 0.0 0.0058 16.9 0.0 4.9 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KUM62094.1 - 0.0021 17.1 0.0 0.061 12.3 0.0 2.9 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KUM62094.1 - 0.0037 16.6 0.0 0.0064 15.9 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain FliO PF04347.13 KUM62094.1 - 0.068 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO RXT2_N PF08595.11 KUM62096.1 - 1.1e-41 142.5 0.0 1.1e-41 142.5 0.0 2.5 2 0 0 2 2 2 1 RXT2-like, N-terminal SPX PF03105.19 KUM62096.1 - 0.45 10.4 14.0 0.82 9.5 14.0 1.4 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 KUM62096.1 - 1.6 7.9 8.7 2.1 7.5 8.7 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Gryzun PF07919.12 KUM62097.1 - 1.9e-235 783.2 0.0 2.3e-235 782.9 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 KUM62097.1 - 1.7e-110 368.7 3.0 6.6e-100 334.0 5.3 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.7 KUM62097.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking PEMT PF04191.13 KUM62098.1 - 6.2e-33 113.4 2.6 6.2e-33 113.4 2.6 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase YrhK PF14145.6 KUM62098.1 - 0.0026 17.6 2.5 0.015 15.2 2.5 2.2 1 1 0 1 1 1 1 YrhK-like protein DUF1223 PF06764.11 KUM62098.1 - 0.0047 17.0 0.0 0.0062 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) ATP1G1_PLM_MAT8 PF02038.16 KUM62098.1 - 0.94 9.0 3.5 0.63 9.5 0.5 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Yae1_N PF09811.9 KUM62100.1 - 2.5e-08 33.5 2.7 3.6e-08 33.0 2.7 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal tRNA-synt_1g PF09334.11 KUM62101.1 - 8.4e-147 489.0 0.0 1.1e-146 488.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KUM62101.1 - 2.1e-08 32.9 0.1 7.3e-05 21.2 0.0 3.6 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KUM62101.1 - 0.0094 15.9 0.1 0.02 14.9 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Spindle_Spc25 PF08234.12 KUM62102.1 - 1.1e-21 76.8 0.0 2.6e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Filament PF00038.21 KUM62102.1 - 0.0014 18.3 13.1 0.0021 17.7 13.1 1.2 1 0 0 1 1 1 1 Intermediate filament protein DUF4140 PF13600.6 KUM62102.1 - 0.54 10.7 5.4 1.2 9.7 5.4 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Rrn6 PF10214.9 KUM62103.1 - 7.5e-215 716.2 0.3 8.5e-215 716.0 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DUF222 PF02720.17 KUM62103.1 - 0.13 11.7 0.0 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF222) HMA PF00403.26 KUM62104.1 - 5.7e-17 61.9 0.7 6.7e-17 61.7 0.7 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 KUM62104.1 - 0.089 13.2 0.2 0.23 11.9 0.1 1.7 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Vps4_C PF09336.10 KUM62104.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 Vps4 C terminal oligomerisation domain DUF2293 PF10056.9 KUM62105.1 - 2.6e-29 101.3 0.2 2.6e-29 101.3 0.2 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) Septin PF00735.18 KUM62106.1 - 7.1e-110 366.7 0.7 8.1e-110 366.5 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KUM62106.1 - 1.1e-07 31.9 0.0 2.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KUM62106.1 - 6.6e-05 22.3 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KUM62106.1 - 0.00033 20.6 0.5 0.0024 17.8 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KUM62106.1 - 0.00053 20.1 0.5 1.3 9.0 0.0 2.6 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KUM62106.1 - 0.0016 18.0 0.6 0.11 12.0 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KUM62106.1 - 0.02 15.4 0.5 0.025 15.1 0.3 1.6 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KUM62106.1 - 0.024 14.9 0.1 0.05 13.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 KUM62106.1 - 0.044 13.1 0.2 0.32 10.3 0.2 2.1 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 KUM62106.1 - 0.086 12.4 0.1 0.64 9.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 KUM62106.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain Ribosomal_L32p PF01783.23 KUM62108.1 - 6.5e-14 51.9 6.1 8.4e-14 51.6 6.1 1.1 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 KUM62108.1 - 0.037 13.4 1.9 0.061 12.8 1.9 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 KUM62108.1 - 0.062 13.3 1.6 0.36 10.9 2.0 1.6 1 1 0 1 1 1 0 Double zinc ribbon JUPITER PF17054.5 KUM62108.1 - 0.1 12.0 0.0 0.1 12.0 0.0 1.0 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter WD40 PF00400.32 KUM62109.1 - 1.7e-18 66.6 18.2 1e-06 29.3 0.7 6.4 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM62109.1 - 8.1e-13 48.5 1.7 8e-05 22.9 0.7 4.6 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KUM62109.1 - 2.4e-05 24.3 0.0 0.0025 17.7 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KUM62109.1 - 0.00048 18.9 0.2 0.0026 16.5 0.1 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KUM62109.1 - 0.0017 16.9 0.1 0.71 8.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 KUM62109.1 - 0.082 12.2 0.0 2.2 7.5 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain Hira PF07569.11 KUM62109.1 - 0.085 12.6 0.1 3.5 7.3 0.0 2.4 2 1 0 2 2 2 0 TUP1-like enhancer of split PD40 PF07676.12 KUM62109.1 - 0.095 12.7 2.6 15 5.7 0.0 3.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat GRAB PF10375.9 KUM62110.1 - 1.1e-08 34.6 0.1 2.4e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Golgin_A5 PF09787.9 KUM62110.1 - 0.0011 18.5 54.3 0.0062 16.0 15.8 3.1 1 1 2 3 3 3 2 Golgin subfamily A member 5 Spc7 PF08317.11 KUM62110.1 - 0.0039 16.1 51.7 0.046 12.6 30.7 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein Fib_alpha PF08702.10 KUM62110.1 - 0.013 15.7 28.6 0.097 12.8 3.5 3.7 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family APC_N_CC PF16689.5 KUM62110.1 - 0.014 15.5 10.7 0.028 14.5 1.9 3.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain Filament PF00038.21 KUM62110.1 - 0.022 14.3 48.2 0.065 12.8 17.8 3.2 1 1 2 3 3 3 0 Intermediate filament protein BST2 PF16716.5 KUM62110.1 - 0.038 14.6 43.4 0.27 11.8 8.7 5.5 2 2 3 5 5 5 0 Bone marrow stromal antigen 2 HALZ PF02183.18 KUM62110.1 - 0.24 11.6 0.1 0.24 11.6 0.1 4.6 4 0 0 4 4 4 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.12 KUM62110.1 - 0.27 11.3 15.9 0.69 10.0 1.0 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 KUM62110.1 - 0.87 9.6 31.4 0.17 11.9 4.6 4.2 1 1 3 4 4 4 0 Laminin Domain II TPR_MLP1_2 PF07926.12 KUM62110.1 - 1.1 9.3 64.3 0.12 12.4 6.0 5.5 2 1 3 6 6 6 0 TPR/MLP1/MLP2-like protein HAUS-augmin3 PF14932.6 KUM62110.1 - 2.1 7.9 47.7 1.3 8.5 12.4 3.3 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 DUF1664 PF07889.12 KUM62110.1 - 2.6 8.1 28.1 0.62 10.1 5.9 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) FAM184 PF15665.5 KUM62110.1 - 2.7 7.7 51.2 0.58 9.9 14.7 3.4 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B HOOK PF05622.12 KUM62110.1 - 3.3 5.7 53.8 4.6 5.3 23.3 2.6 1 1 2 3 3 3 0 HOOK protein NPV_P10 PF05531.12 KUM62110.1 - 3.4 8.2 18.6 4.1 8.0 0.2 4.6 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.6 KUM62110.1 - 4.9 6.9 43.9 0.74 9.5 19.8 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) DUF812 PF05667.11 KUM62110.1 - 6.3 5.5 51.0 5 5.9 34.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF3584 PF12128.8 KUM62110.1 - 6.4 4.1 49.9 13 3.2 49.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.6 KUM62110.1 - 7.1 5.9 52.7 0.17 11.3 7.4 4.1 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding CBFD_NFYB_HMF PF00808.23 KUM62111.1 - 4.5e-18 65.3 0.3 7.9e-18 64.5 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KUM62111.1 - 5.9e-08 33.1 1.3 1.5e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KUM62111.1 - 0.0083 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated DUF5333 PF17267.2 KUM62111.1 - 0.013 15.6 0.8 0.018 15.2 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5333) SPOB_ab PF14682.6 KUM62111.1 - 0.027 14.6 0.4 0.036 14.1 0.4 1.2 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal TFIID-31kDa PF02291.15 KUM62111.1 - 0.078 13.1 0.0 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit YolD PF08863.10 KUM62111.1 - 0.43 10.7 7.1 0.4 10.8 5.5 1.7 2 0 0 2 2 2 0 YolD-like protein Actin PF00022.19 KUM62112.1 - 1.2e-20 73.6 0.0 3.2e-17 62.2 0.0 3.1 3 0 0 3 3 3 3 Actin RhoGAP-FF1 PF16512.5 KUM62112.1 - 0.12 13.0 0.1 0.24 12.1 0.1 1.4 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain Kin17_mid PF10357.9 KUM62113.1 - 3.1e-51 172.5 0.8 5.1e-51 171.8 0.8 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 KUM62113.1 - 0.041 14.3 3.8 0.092 13.2 3.8 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Ribosomal_S18 PF01084.20 KUM62113.1 - 0.056 13.7 0.9 0.16 12.2 0.9 1.7 1 0 0 1 1 1 0 Ribosomal protein S18 zf-C2H2_2 PF12756.7 KUM62113.1 - 0.12 12.7 2.6 0.3 11.5 0.4 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Mucin PF01456.17 KUM62113.1 - 0.2 11.7 7.7 0.33 10.9 7.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein CarbpepA_inh PF02977.15 KUM62113.1 - 0.25 11.2 2.3 0.51 10.2 2.3 1.4 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor zf-C2H2_jaz PF12171.8 KUM62113.1 - 0.27 11.6 3.5 0.63 10.4 3.5 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding PTR2 PF00854.21 KUM62114.1 - 1.9e-57 194.9 5.9 1.9e-57 194.9 5.9 1.4 1 1 0 1 1 1 1 POT family Phage_holin_3_6 PF07332.11 KUM62114.1 - 0.022 14.8 0.7 0.022 14.8 0.7 3.9 4 1 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III CcmH PF03918.14 KUM62114.1 - 0.2 11.0 0.2 2.4 7.5 0.1 2.4 2 0 0 2 2 2 0 Cytochrome C biogenesis protein MFS_1 PF07690.16 KUM62115.1 - 1.3e-39 136.1 29.2 1.3e-39 136.1 29.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM62115.1 - 6.2e-10 38.5 28.7 9.4e-10 37.9 27.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KUM62115.1 - 0.0026 17.1 7.5 0.0026 17.1 7.5 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB SIR2 PF02146.17 KUM62118.1 - 3.9e-50 170.2 0.0 6.6e-50 169.5 0.0 1.4 1 0 0 1 1 1 1 Sir2 family Cupin_2 PF07883.11 KUM62119.1 - 1.2e-07 31.3 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain MFS_1 PF07690.16 KUM62120.1 - 5.7e-32 111.0 53.0 2.2e-27 95.9 30.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1279 PF06916.13 KUM62120.1 - 0.34 11.5 2.5 17 6.0 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) Fungal_trans PF04082.18 KUM62122.1 - 8.3e-05 21.7 0.7 0.00013 21.1 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_32C PF08244.12 KUM62123.1 - 1e-22 80.8 0.8 1.6e-22 80.2 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 KUM62123.1 - 3.5e-14 53.1 0.0 5.9e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain zf-CCCH PF00642.24 KUM62124.1 - 3.2e-08 33.3 20.0 3e-07 30.2 2.5 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KUM62124.1 - 0.0058 16.7 3.3 0.0058 16.7 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 KUM62124.1 - 0.007 17.0 2.3 0.45 11.2 0.3 2.5 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 KUM62124.1 - 0.0079 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SCRG1 PF15224.6 KUM62124.1 - 0.23 11.6 3.7 0.25 11.5 0.1 2.3 2 0 0 2 2 2 0 Scrapie-responsive protein 1 zf-CCCH_3 PF15663.5 KUM62124.1 - 2.3 8.5 7.9 0.4 10.9 1.4 2.4 2 2 0 2 2 2 0 Zinc-finger containing family SMC_Nse1 PF07574.13 KUM62125.1 - 3.5e-66 222.8 0.2 4.5e-66 222.5 0.2 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KUM62125.1 - 2.1e-14 53.5 10.6 3.6e-14 52.8 10.6 1.4 1 0 0 1 1 1 1 RING-like domain zf-ANAPC11 PF12861.7 KUM62125.1 - 0.0013 18.7 2.4 0.0023 17.9 2.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KUM62125.1 - 0.0087 16.4 7.8 0.015 15.7 7.8 1.4 1 0 0 1 1 1 1 Ring finger domain DUF4796 PF16044.5 KUM62125.1 - 0.015 14.9 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Zn_ribbon_17 PF17120.5 KUM62125.1 - 0.46 10.1 5.9 0.8 9.4 5.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 KUM62125.1 - 0.48 10.3 9.6 0.13 12.2 4.4 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYDLN_acid PF09538.10 KUM62125.1 - 0.54 11.0 4.5 0.15 12.8 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-rbx1 PF12678.7 KUM62125.1 - 0.66 10.3 5.3 1.4 9.2 5.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KUM62125.1 - 0.92 9.4 8.0 1.7 8.5 8.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KUM62125.1 - 1.1 9.5 5.8 3.5 7.9 5.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 KUM62125.1 - 1.5 8.8 7.9 2.6 7.9 7.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YdjO PF14169.6 KUM62125.1 - 1.8 8.3 6.1 4.5 7.1 6.1 1.6 1 0 0 1 1 1 0 Cold-inducible protein YdjO Glyco_hydro_65N PF03636.15 KUM62126.1 - 3e-31 108.8 0.0 1e-30 107.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 KUM62126.1 - 2.4e-23 82.6 3.7 3.7e-17 62.3 0.4 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 KUM62126.1 - 0.00055 19.8 0.1 0.0013 18.6 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain 3Beta_HSD PF01073.19 KUM62127.1 - 3.4e-07 29.6 0.0 8.3e-07 28.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KUM62127.1 - 1.3e-05 24.8 0.0 3.3e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KUM62127.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H-binding adh_short PF00106.25 KUM62128.1 - 3.7e-45 153.8 0.2 4.3e-45 153.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM62128.1 - 5.1e-32 111.3 0.1 6.4e-32 111.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM62128.1 - 4e-14 52.9 0.3 6.4e-14 52.3 0.3 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KUM62128.1 - 2.8e-05 24.1 0.5 4e-05 23.6 0.5 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KUM62128.1 - 0.00065 19.2 0.1 0.0035 16.8 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KUM62128.1 - 0.023 14.8 0.1 0.036 14.1 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KUM62128.1 - 0.063 13.9 0.1 0.21 12.2 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 KUM62128.1 - 0.11 12.1 0.6 0.23 11.0 0.3 1.7 2 0 0 2 2 2 0 NmrA-like family DUF1776 PF08643.10 KUM62128.1 - 0.17 11.3 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KUM62130.1 - 4.4e-22 78.5 0.0 5.1e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM62130.1 - 9e-16 58.1 0.0 1.2e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM62130.1 - 1.5e-10 41.3 0.0 1.9e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM62130.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.24 KUM62131.1 - 5.4e-107 358.4 20.4 6.1e-107 358.3 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM62131.1 - 6.9e-21 74.6 33.1 3.1e-17 62.5 3.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KUM62131.1 - 1.9 6.6 11.4 0.014 13.7 1.7 2.2 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 KUM62132.1 - 4.7e-61 206.9 0.0 6.8e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S28 PF05577.12 KUM62133.1 - 5.9e-56 190.1 5.5 1.8e-55 188.5 5.0 1.9 2 1 0 2 2 2 1 Serine carboxypeptidase S28 DAO PF01266.24 KUM62134.1 - 1.2e-42 146.8 0.1 1.4e-42 146.6 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KUM62134.1 - 0.00047 20.7 0.1 0.23 12.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM62134.1 - 0.0042 16.3 0.1 1.5 8.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KUM62134.1 - 0.018 13.6 0.0 0.091 11.3 0.0 1.8 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.6 KUM62134.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain KHA PF11834.8 KUM62134.1 - 0.063 13.4 0.5 0.35 11.0 0.1 2.2 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel Catalase PF00199.19 KUM62135.1 - 4.7e-164 546.1 0.1 6.4e-164 545.6 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 KUM62135.1 - 8.3e-50 168.4 0.7 1.4e-49 167.7 0.7 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 KUM62135.1 - 2.9e-17 62.6 0.1 6.9e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Acetyltransf_1 PF00583.25 KUM62136.1 - 3.4e-08 33.7 0.0 4.1e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KUM62136.1 - 4e-06 26.8 0.0 6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KUM62136.1 - 7e-06 26.4 0.0 1.1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KUM62136.1 - 0.005 16.9 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Na_Ca_ex PF01699.24 KUM62137.1 - 2.9e-30 105.2 37.2 3.6e-16 59.5 14.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Fungal_trans_2 PF11951.8 KUM62138.1 - 3.3e-19 69.0 6.1 2e-18 66.4 6.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM62138.1 - 3.9e-05 23.7 14.4 3.9e-05 23.7 14.4 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM62138.1 - 0.061 12.4 0.4 0.13 11.3 0.4 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain EHN PF06441.12 KUM62139.1 - 4.1e-30 104.3 0.0 8e-30 103.4 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KUM62139.1 - 6.8e-14 52.1 0.0 1.1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KUM62139.1 - 0.00041 21.0 0.0 0.0013 19.4 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family ADPRTs_Tse2 PF18648.1 KUM62139.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Tse2 ADP-ribosyltransferase toxins Cupin_2 PF07883.11 KUM62140.1 - 3.1e-05 23.6 0.1 5e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Pyridoxal_deC PF00282.19 KUM62141.1 - 2.1e-99 332.8 0.0 2.5e-99 332.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain adh_short_C2 PF13561.6 KUM62142.1 - 4.8e-21 75.4 0.0 5.2e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM62142.1 - 0.0002 20.9 0.0 0.00023 20.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Ank_2 PF12796.7 KUM62143.1 - 4.8e-78 257.8 27.7 6.5e-14 52.3 0.1 15.1 5 4 9 15 15 15 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM62143.1 - 1.2e-73 242.6 27.5 5.8e-10 39.5 0.3 22.9 16 3 8 24 24 24 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM62143.1 - 1.9e-59 190.6 33.2 2.6e-05 24.2 0.0 24.9 27 0 0 27 27 26 11 Ankyrin repeat Ank PF00023.30 KUM62143.1 - 2.6e-56 185.7 57.6 2.4e-06 27.7 0.1 24.6 26 2 0 26 26 25 12 Ankyrin repeat Ank_5 PF13857.6 KUM62143.1 - 1.5e-48 162.2 46.9 1.2e-08 35.0 0.4 19.7 17 5 7 24 24 22 11 Ankyrin repeats (many copies) NACHT PF05729.12 KUM62143.1 - 1.5e-08 34.7 0.0 4.2e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KUM62143.1 - 9.6e-07 29.3 0.1 4.5e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KUM62143.1 - 0.036 14.4 0.0 0.096 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KUM62143.1 - 0.046 13.0 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 KUM62143.1 - 0.049 13.4 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_35 PF14516.6 KUM62143.1 - 0.086 11.7 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain APS_kinase PF01583.20 KUM62143.1 - 0.17 11.7 0.0 0.46 10.4 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase ATPase_2 PF01637.18 KUM62143.1 - 0.2 11.5 0.0 2 8.3 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KUM62143.1 - 0.22 10.7 0.0 0.48 9.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Sel_put PF04328.13 KUM62143.1 - 0.97 9.5 4.2 0.27 11.3 0.7 1.9 2 0 0 2 2 2 0 Selenoprotein, putative Pex2_Pex12 PF04757.14 KUM62144.1 - 7.1e-47 159.9 5.3 9.6e-47 159.4 5.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KUM62144.1 - 4e-12 45.8 9.5 6.4e-12 45.1 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KUM62144.1 - 4.4e-10 39.3 6.8 6.9e-10 38.6 6.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM62144.1 - 5.8e-10 38.9 7.4 8.9e-10 38.3 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KUM62144.1 - 8.7e-10 38.8 10.3 1.3e-09 38.2 10.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KUM62144.1 - 3.9e-07 30.0 7.7 8.3e-07 28.9 7.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KUM62144.1 - 5.8e-07 29.3 6.8 9.6e-07 28.6 6.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KUM62144.1 - 1.3e-06 28.2 6.7 2.1e-06 27.5 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KUM62144.1 - 1.6e-05 25.0 8.6 2.7e-05 24.2 8.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KUM62144.1 - 4e-05 23.8 8.7 8.5e-05 22.8 8.7 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KUM62144.1 - 0.0018 18.4 6.5 0.003 17.7 6.5 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KUM62144.1 - 0.038 13.9 2.7 0.068 13.1 2.7 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KUM62144.1 - 0.069 13.2 3.5 0.12 12.5 3.0 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KUM62144.1 - 0.17 11.7 7.4 0.35 10.7 7.4 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 KUM62144.1 - 0.55 10.5 4.7 1.3 9.3 4.7 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DNA_pol_A_exo1 PF01612.20 KUM62145.1 - 1.9e-17 63.5 0.0 5e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 3'-5' exonuclease HTH_3 PF01381.22 KUM62145.1 - 0.073 13.1 0.2 17 5.6 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix DUF2744 PF10910.8 KUM62145.1 - 0.089 12.8 0.2 12 5.8 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2744) Nop25 PF09805.9 KUM62146.1 - 4.2e-36 124.4 16.0 4.2e-36 124.4 16.0 2.8 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) Cu_amine_oxid PF01179.20 KUM62147.1 - 2.7e-163 543.7 1.7 3.2e-163 543.4 1.7 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KUM62147.1 - 0.0029 17.8 0.1 0.0057 16.9 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KUM62147.1 - 0.0072 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain EXS PF03124.14 KUM62148.1 - 6.5e-99 331.4 18.2 7.4e-99 331.2 18.2 1.0 1 0 0 1 1 1 1 EXS family CMAS PF02353.20 KUM62149.1 - 7.3e-61 205.9 0.1 9.3e-61 205.5 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KUM62149.1 - 8.3e-10 39.2 0.0 1.7e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM62149.1 - 1e-09 38.5 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM62149.1 - 1.2e-08 35.5 0.0 2.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM62149.1 - 3e-05 24.7 0.0 5.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KUM62149.1 - 0.0051 16.4 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 KUM62149.1 - 0.0064 16.0 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 FtsJ PF01728.19 KUM62149.1 - 0.026 14.6 0.0 0.05 13.7 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 KUM62149.1 - 0.029 14.1 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KUM62149.1 - 0.035 13.7 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 KUM62149.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PHtD_u1 PF16645.5 KUM62150.1 - 0.017 15.6 0.5 0.06 13.8 0.5 1.9 1 0 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein Tropomyosin_1 PF12718.7 KUM62151.1 - 8.2e-49 165.4 36.1 9.7e-49 165.2 36.1 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KUM62151.1 - 1.7e-09 37.4 35.8 0.00013 21.4 14.2 2.9 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.9 KUM62151.1 - 0.0006 19.9 5.7 0.0006 19.9 5.7 2.9 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.13 KUM62151.1 - 0.0083 16.5 37.1 0.048 14.0 15.8 2.1 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region KLRAQ PF10205.9 KUM62151.1 - 0.009 16.2 23.8 0.019 15.2 9.6 2.8 1 1 2 3 3 3 2 Predicted coiled-coil domain-containing protein KASH_CCD PF14662.6 KUM62151.1 - 0.0093 15.8 32.9 0.018 14.9 23.0 2.1 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH CASP_C PF08172.12 KUM62151.1 - 0.027 13.8 19.6 0.29 10.4 0.8 2.1 2 0 0 2 2 2 0 CASP C terminal GAS PF13851.6 KUM62151.1 - 0.041 13.2 32.0 0.46 9.8 22.8 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KUM62151.1 - 0.044 12.7 34.2 0.25 10.2 12.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 KUM62151.1 - 0.044 14.0 34.8 1.4 9.1 15.3 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 KUM62151.1 - 0.055 13.5 20.6 0.25 11.4 8.6 2.2 1 1 1 2 2 2 0 Laminin Domain II ADIP PF11559.8 KUM62151.1 - 0.16 12.1 33.2 2.8 8.0 10.7 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.6 KUM62151.1 - 0.18 12.2 34.1 0.38 11.1 16.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Fez1 PF06818.15 KUM62151.1 - 0.22 11.9 28.5 1.2 9.6 20.7 2.0 1 1 1 2 2 2 0 Fez1 bZIP_1 PF00170.21 KUM62151.1 - 0.32 11.1 30.8 2.7 8.1 0.9 4.3 2 1 2 4 4 4 0 bZIP transcription factor HOOK PF05622.12 KUM62151.1 - 0.33 9.1 28.6 0.39 8.8 28.6 1.1 1 0 0 1 1 1 0 HOOK protein DHR10 PF18595.1 KUM62151.1 - 0.39 10.8 36.5 1.9 8.6 13.4 2.6 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF3450 PF11932.8 KUM62151.1 - 0.4 9.9 29.3 0.096 12.0 5.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 KUM62151.1 - 0.51 10.2 26.9 0.55 10.0 10.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) MPS2 PF17060.5 KUM62151.1 - 0.62 9.3 18.0 1.1 8.5 17.9 1.4 1 1 0 1 1 1 0 Monopolar spindle protein 2 Fmp27_WPPW PF10359.9 KUM62151.1 - 0.78 8.5 27.8 0.14 11.0 11.8 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain TMF_TATA_bd PF12325.8 KUM62151.1 - 0.93 9.7 28.6 3 8.1 18.2 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding PI3K_P85_iSH2 PF16454.5 KUM62151.1 - 1 8.9 28.8 1.1 8.8 20.2 2.0 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain bZIP_2 PF07716.15 KUM62151.1 - 1.1 9.3 36.3 0.99 9.5 3.1 5.1 2 2 3 5 5 5 0 Basic region leucine zipper UPF0242 PF06785.11 KUM62151.1 - 1.2 9.2 34.3 5.3 7.1 15.2 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 KUM62151.1 - 1.2 9.3 33.9 1.2 9.4 23.3 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 KUM62151.1 - 1.3 8.1 26.0 0.68 9.0 10.9 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 KUM62151.1 - 1.5 8.9 16.8 4.6 7.3 6.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 KUM62151.1 - 1.5 8.9 27.0 1.1 9.3 9.1 3.1 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Cep57_CLD_2 PF14197.6 KUM62151.1 - 1.6 8.9 34.6 2.8 8.1 3.3 4.1 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 NABP PF07990.12 KUM62151.1 - 1.7 8.1 7.5 1.8 8.0 7.5 1.2 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Lebercilin PF15619.6 KUM62151.1 - 1.8 8.2 35.3 0.83 9.3 16.3 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 KUM62151.1 - 1.8 9.1 41.0 1.6 9.2 28.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region FlaC_arch PF05377.11 KUM62151.1 - 2.2 8.8 20.2 6 7.3 0.2 4.4 1 1 3 5 5 5 0 Flagella accessory protein C (FlaC) DUF745 PF05335.13 KUM62151.1 - 2.6 7.7 24.8 0.66 9.7 5.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) SlyX PF04102.12 KUM62151.1 - 2.7 8.7 26.2 3.8 8.2 2.3 3.9 1 1 4 5 5 5 0 SlyX TPR_MLP1_2 PF07926.12 KUM62151.1 - 2.9 8.0 38.0 1.2 9.2 12.8 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 KUM62151.1 - 2.9 7.1 25.9 4.8 6.4 25.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MAD PF05557.13 KUM62151.1 - 3.1 6.0 32.2 2.5 6.4 21.5 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein ZapB PF06005.12 KUM62151.1 - 3.3 8.2 39.7 1.5 9.3 1.8 3.9 1 1 3 4 4 4 0 Cell division protein ZapB DUF812 PF05667.11 KUM62151.1 - 6.9 5.4 31.0 9.5 5.0 31.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) YabA PF06156.13 KUM62151.1 - 7.8 7.2 27.1 3.3 8.4 9.5 2.9 1 1 2 3 3 3 0 Initiation control protein YabA DUF16 PF01519.16 KUM62151.1 - 8.3 7.0 23.0 7 7.2 5.6 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 ERM PF00769.19 KUM62151.1 - 8.8 6.1 38.4 3.7 7.3 15.7 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family VGPC1_C PF16799.5 KUM62151.1 - 9.4 6.3 14.3 0.45 10.5 3.2 3.2 2 1 1 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 MR_MLE_C PF13378.6 KUM62152.1 - 3.2e-41 141.3 0.0 4.1e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KUM62152.1 - 1.1e-09 38.5 0.0 1.8e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Amidohydro_2 PF04909.14 KUM62153.1 - 3.9e-16 59.7 0.8 7e-16 58.9 0.1 1.7 2 0 0 2 2 2 1 Amidohydrolase adh_short_C2 PF13561.6 KUM62154.1 - 7.6e-54 182.7 0.0 9e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM62154.1 - 6.5e-43 146.5 0.1 8.2e-43 146.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM62154.1 - 3.1e-10 40.3 0.4 5e-10 39.6 0.4 1.2 1 0 0 1 1 1 1 KR domain Lactamase_B_2 PF12706.7 KUM62155.1 - 4.1e-11 42.8 0.1 6.4e-11 42.2 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KUM62155.1 - 1.2e-08 35.1 0.0 1.6e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain LOR PF04525.12 KUM62156.1 - 2.3e-09 37.1 0.0 3.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 LURP-one-related LSM PF01423.22 KUM62157.1 - 4e-20 71.3 0.1 4.4e-20 71.1 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KUM62157.1 - 0.11 12.7 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain AA_permease PF00324.21 KUM62158.1 - 1.4e-145 485.6 39.4 1.7e-145 485.3 39.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM62158.1 - 1.5e-37 129.5 38.6 1.8e-37 129.2 38.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KUM62158.1 - 0.03 13.2 1.3 0.059 12.2 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) RhoGAP PF00620.27 KUM62159.1 - 4.5e-15 55.8 0.1 1e-14 54.6 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 KUM62159.1 - 2.5e-08 33.9 0.0 5.2e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KUM62159.1 - 9.4e-08 32.2 0.0 2.8e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Phage_TAC_8 PF10666.9 KUM62159.1 - 0.083 13.2 0.4 0.53 10.6 0.1 2.3 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Gp14 ()A118 Suppressor_APC PF11414.8 KUM62160.1 - 0.091 12.8 0.2 0.72 10.0 0.1 2.0 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein FAM86 PF14904.6 KUM62161.1 - 0.033 14.3 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function PRKCSH-like PF12999.7 KUM62163.1 - 1.6e-43 148.5 14.4 1e-26 93.8 1.6 3.3 4 0 0 4 4 4 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KUM62163.1 - 8.2e-33 113.3 8.0 1.2e-32 112.8 3.3 2.7 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KUM62163.1 - 1.4e-07 32.4 1.4 4.3e-07 30.8 1.4 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 KUM62163.1 - 0.0012 18.8 1.1 0.0012 18.8 1.1 1.7 2 0 0 2 2 2 1 Autophagy-related protein 27 MRP-S25 PF13741.6 KUM62163.1 - 0.0027 17.3 0.5 0.0053 16.3 0.5 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 PRCC PF10253.9 KUM62163.1 - 0.029 15.2 0.2 0.064 14.0 0.2 1.6 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF4407 PF14362.6 KUM62163.1 - 0.044 13.1 13.4 0.12 11.7 9.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 KUM62163.1 - 0.061 13.5 6.5 0.46 10.7 0.1 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family GTP-bdg_M PF16360.5 KUM62163.1 - 0.39 11.4 6.7 0.12 12.9 1.9 2.7 2 2 1 3 3 3 0 GTP-binding GTPase Middle Region NPV_P10 PF05531.12 KUM62163.1 - 1.2 9.6 3.6 9.7 6.7 0.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Ldl_recept_a PF00057.18 KUM62163.1 - 4 7.7 14.0 0.65 10.3 1.9 3.1 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A Aldo_ket_red PF00248.21 KUM62164.1 - 1.2e-65 221.7 0.0 1.6e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 KUM62165.1 - 8.5e-36 123.6 32.6 1.6e-35 122.7 32.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KUM62166.1 - 2.3e-44 151.8 0.1 3.3e-44 151.3 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM62166.1 - 7e-05 22.9 12.3 0.00014 21.9 12.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L50 PF10501.9 KUM62167.1 - 1.1e-16 61.0 0.1 1.8e-16 60.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S Pam16 PF03656.13 KUM62169.1 - 1.8e-31 108.8 0.5 2.2e-31 108.5 0.5 1.0 1 0 0 1 1 1 1 Pam16 Pex24p PF06398.11 KUM62170.1 - 7.9e-100 334.4 0.3 1.1e-99 333.9 0.3 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Wzy_C PF04932.15 KUM62170.1 - 0.076 12.6 0.2 0.37 10.4 0.2 2.1 1 1 0 1 1 1 0 O-Antigen ligase XRCC4 PF06632.12 KUM62170.1 - 0.62 8.9 6.7 0.94 8.3 6.7 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 PAP_assoc PF03828.19 KUM62173.1 - 2.2e-10 40.6 1.2 1.1e-09 38.3 0.7 2.5 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KUM62173.1 - 8.4e-10 38.8 0.0 1.9e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KUM62173.1 - 0.082 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase adh_short PF00106.25 KUM62174.1 - 6.1e-27 94.4 0.0 6.3e-26 91.0 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM62174.1 - 4.8e-20 72.1 0.0 2.3e-19 69.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KUM62174.1 - 6.2e-05 22.5 0.1 0.00031 20.2 0.1 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KUM62174.1 - 0.0016 18.4 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KUM62174.1 - 0.051 13.5 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 KUM62174.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family MFS_1 PF07690.16 KUM62175.1 - 1.4e-43 149.2 58.8 1.4e-42 145.9 56.1 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM62175.1 - 9.7e-16 57.3 29.1 1.5e-15 56.7 29.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM62175.1 - 2.3e-12 46.5 39.2 4.3e-12 45.6 16.2 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter Fungal_trans PF04082.18 KUM62176.1 - 5.6e-25 87.9 0.5 8.2e-25 87.3 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM62176.1 - 3.6e-07 30.2 10.8 6.1e-07 29.5 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-synt_S1 PF05827.12 KUM62177.1 - 4.5e-05 23.3 0.1 7.5e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) OAD_gamma PF04277.13 KUM62177.1 - 0.015 15.8 0.3 0.027 15.0 0.3 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Presenilin PF01080.17 KUM62178.1 - 0.0037 16.1 4.0 0.005 15.7 4.0 1.2 1 0 0 1 1 1 1 Presenilin Apt1 PF10351.9 KUM62178.1 - 0.0044 15.9 16.3 0.0054 15.6 16.3 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain PI3K_1B_p101 PF10486.9 KUM62178.1 - 0.048 11.5 11.0 0.06 11.1 11.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Miga PF10265.9 KUM62178.1 - 0.79 8.6 10.6 1.2 8.1 10.6 1.3 1 0 0 1 1 1 0 Mitoguardin GCOM2 PF15328.6 KUM62178.1 - 0.98 9.8 13.7 1.4 9.2 13.7 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 Macoilin PF09726.9 KUM62178.1 - 3.1 6.3 22.2 4.6 5.7 22.2 1.2 1 0 0 1 1 1 0 Macoilin family Med13_C PF06333.12 KUM62178.1 - 3.3 6.9 23.7 0.062 12.6 16.5 1.7 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain Thiolase_C PF02803.18 KUM62179.1 - 2e-44 150.2 0.9 2.9e-44 149.6 0.9 1.2 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 KUM62179.1 - 1.3e-14 54.2 0.1 2.2e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_deac_2 PF04748.13 KUM62179.1 - 0.015 14.5 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Rtf2 PF04641.12 KUM62180.1 - 1.9e-64 217.6 0.1 2.6e-64 217.1 0.1 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KUM62180.1 - 1e-09 38.1 0.3 0.0022 17.8 0.0 3.3 2 1 1 3 3 3 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 KUM62180.1 - 0.0013 18.7 0.1 0.0026 17.7 0.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KUM62180.1 - 0.0032 17.5 0.9 0.0082 16.2 0.2 2.1 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KUM62180.1 - 0.019 14.8 0.3 0.6 10.0 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-NOSIP PF15906.5 KUM62180.1 - 0.022 14.9 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 KUM62180.1 - 0.038 13.9 0.2 0.079 12.8 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KUM62180.1 - 0.062 13.2 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KUM62180.1 - 0.095 13.1 0.2 0.27 11.6 0.2 1.8 1 0 0 1 1 1 0 Ring finger domain Amidase PF01425.21 KUM62181.1 - 2.7e-98 329.9 0.0 9.8e-98 328.0 0.0 1.7 1 1 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.8 KUM62182.1 - 6.8e-11 41.6 0.3 1.6e-09 37.1 0.3 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM62182.1 - 2.2e-05 24.4 9.2 2.2e-05 24.4 9.2 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KUM62183.1 - 7.6e-13 48.4 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM62183.1 - 0.00032 20.1 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KUM62183.1 - 0.014 15.3 0.1 0.047 13.6 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KUM62183.1 - 0.055 12.2 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KUM62183.1 - 0.085 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF3632 PF12311.8 KUM62184.1 - 2.3e-31 109.6 0.3 3.3e-31 109.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Polyketide_cyc2 PF10604.9 KUM62186.1 - 0.00011 22.5 12.1 0.003 17.8 12.1 2.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KUM62186.1 - 0.0026 18.0 2.0 0.0026 18.0 2.0 2.1 2 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport DEC-1_N PF04625.13 KUM62186.1 - 0.16 10.9 2.8 0.19 10.7 2.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF4106 PF13388.6 KUM62186.1 - 7.1 5.7 6.0 8.9 5.4 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) RrnaAD PF00398.20 KUM62187.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase JAB PF01398.21 KUM62188.1 - 1.1e-13 51.2 0.0 2.9e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KUM62188.1 - 4.5e-10 39.7 1.6 7.3e-10 39.0 1.6 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KUM62188.1 - 0.00011 22.0 0.0 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain 4HBT PF03061.22 KUM62189.1 - 3.4e-07 30.5 0.0 5.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily HET PF06985.11 KUM62191.1 - 5.6e-09 36.5 0.2 1e-08 35.7 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RRM_1 PF00076.22 KUM62193.1 - 6.6e-19 67.5 0.0 9.3e-19 67.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lipocalin_4 PF13648.6 KUM62194.1 - 0.21 12.5 6.5 0.25 12.3 0.2 2.7 2 1 0 2 2 2 0 Lipocalin-like domain WD40 PF00400.32 KUM62195.1 - 1.7e-27 95.1 2.2 6.5e-09 36.3 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM62195.1 - 4.2e-13 49.4 0.1 0.0016 18.7 0.1 5.7 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KUM62195.1 - 6.1e-06 26.0 0.1 2.7e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 PQQ-like domain WD40_like PF17005.5 KUM62195.1 - 0.00086 18.7 0.0 0.027 13.8 0.0 2.9 2 1 2 4 4 4 1 WD40-like domain Gmad1 PF10647.9 KUM62195.1 - 0.0014 18.5 0.1 0.0035 17.1 0.1 1.6 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KUM62195.1 - 0.0059 15.3 0.1 0.0088 14.7 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ChaC PF04752.12 KUM62198.1 - 1e-53 182.0 0.0 1.3e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein DUF4695 PF15766.5 KUM62198.1 - 0.4 10.9 1.3 0.72 10.1 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) DUF3433 PF11915.8 KUM62199.1 - 8.9e-37 125.4 14.8 4.2e-21 75.2 1.5 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) COX2_TM PF02790.15 KUM62199.1 - 0.015 15.4 6.5 0.46 10.7 0.2 3.1 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain adh_short PF00106.25 KUM62200.1 - 2.6e-17 62.9 0.0 1.5e-16 60.5 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM62200.1 - 2.5e-11 43.6 0.0 8.4e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM62200.1 - 1.9e-06 27.9 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Zn_clus PF00172.18 KUM62201.1 - 5.2e-05 23.3 7.8 0.00016 21.8 7.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM62201.1 - 0.00011 21.2 0.1 0.00015 20.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_32N PF00251.20 KUM62202.1 - 1.4e-42 146.3 0.2 2e-41 142.6 0.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KUM62202.1 - 1.6e-31 109.4 0.0 2.4e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 KUM62202.1 - 0.00026 21.1 0.0 0.00066 19.8 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4975) BNR PF02012.20 KUM62202.1 - 0.048 13.7 2.8 0.061 13.3 0.2 2.7 2 0 0 2 2 2 0 BNR/Asp-box repeat CHB_HEX_C PF03174.13 KUM62202.1 - 0.13 12.2 0.5 0.53 10.3 0.1 2.2 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain Ank_2 PF12796.7 KUM62205.1 - 2.5e-42 143.3 7.2 5.4e-15 55.8 0.1 5.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM62205.1 - 2e-32 111.1 2.0 2.4e-07 31.2 0.0 6.9 3 1 5 8 8 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KUM62205.1 - 6.9e-31 105.3 4.9 0.0012 19.2 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 KUM62205.1 - 3.6e-20 69.9 0.0 0.29 11.8 0.0 9.4 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 KUM62205.1 - 3.9e-13 49.4 1.3 0.004 17.4 0.0 6.4 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KUM62205.1 - 4.2e-12 45.9 0.1 8.6e-12 44.9 0.1 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 KUM62205.1 - 1.5e-07 31.5 0.0 3.7e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KUM62205.1 - 9.4e-05 22.9 0.0 0.00042 20.7 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KUM62205.1 - 0.0055 17.0 0.0 0.024 14.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KUM62205.1 - 0.053 12.7 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 KUM62205.1 - 0.061 13.4 0.0 1.1 9.3 0.0 2.7 1 1 0 1 1 1 0 AAA domain Nitro_FeMo-Co PF02579.17 KUM62205.1 - 2.6 8.4 4.9 32 4.9 1.9 3.8 1 1 2 3 3 3 0 Dinitrogenase iron-molybdenum cofactor DUF1843 PF08898.10 KUM62205.1 - 4.1 8.0 4.9 47 4.6 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) LCE6A PF15858.5 KUM62206.1 - 0.14 12.9 4.8 0.19 12.5 4.8 1.3 1 1 0 1 1 1 0 Late cornified envelope protein 6A family eIF-5_eIF-2B PF01873.17 KUM62207.1 - 4.7e-40 136.1 0.2 7.2e-40 135.5 0.2 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KUM62207.1 - 0.18 11.4 1.3 0.33 10.5 1.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 KUM62207.1 - 1.2 9.5 7.4 1.1 9.7 0.4 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain AIM24 PF01987.17 KUM62208.1 - 1.5e-43 149.0 0.0 1.6e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Ank_2 PF12796.7 KUM62209.1 - 1.7e-42 143.9 10.2 8.2e-14 52.0 0.0 3.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM62209.1 - 1.2e-30 105.4 6.4 2.4e-10 40.7 0.1 5.8 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM62209.1 - 1.2e-19 70.1 13.2 2.1e-11 43.8 0.3 4.8 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KUM62209.1 - 3.4e-18 65.2 12.4 5.5e-07 29.8 0.4 6.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 KUM62209.1 - 3.3e-17 60.8 4.8 0.00031 21.0 0.1 7.0 7 0 0 7 7 7 3 Ankyrin repeat SH3_1 PF00018.28 KUM62210.1 - 9.2e-14 50.8 0.0 1.4e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KUM62210.1 - 1.2e-12 47.4 0.1 3e-12 46.2 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KUM62210.1 - 1.2e-07 31.3 0.0 1.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain MBF1 PF08523.10 KUM62211.1 - 8.4e-23 80.6 0.8 1.7e-22 79.7 0.8 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KUM62211.1 - 4.8e-09 36.1 0.1 8.2e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KUM62211.1 - 0.00043 20.6 0.0 0.0011 19.3 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain FTHFS PF01268.19 KUM62212.1 - 2.1e-252 838.3 0.0 3e-252 837.8 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KUM62212.1 - 1.3e-66 222.8 0.8 3.1e-66 221.6 0.8 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KUM62212.1 - 2.8e-37 127.5 0.6 6.2e-37 126.4 0.6 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KUM62212.1 - 0.0047 15.9 0.1 0.011 14.7 0.1 1.5 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GTP_EFTU PF00009.27 KUM62212.1 - 0.018 14.5 0.3 0.045 13.3 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NHase_alpha PF02979.16 KUM62213.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain Iso_dh PF00180.20 KUM62214.1 - 9.4e-70 235.5 0.0 1.1e-69 235.2 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CAP_GLY PF01302.25 KUM62216.1 - 1.6e-25 88.9 0.0 2.4e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KUM62216.1 - 8.1e-14 51.8 0.0 1.3e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KUM62216.1 - 0.00025 20.7 0.0 0.0012 18.5 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family CENP-C_C PF11699.8 KUM62217.1 - 5.4e-37 125.9 0.7 9.7e-37 125.1 0.7 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 KUM62217.1 - 3e-34 118.6 6.6 3e-34 118.6 6.6 3.6 2 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 KUM62217.1 - 9.8e-07 28.4 0.0 2.7e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KUM62217.1 - 0.016 14.8 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Cupin GAGA_bind PF06217.12 KUM62217.1 - 4.6 7.4 13.5 0.83 9.9 0.6 2.8 3 0 0 3 3 3 0 GAGA binding protein-like family RNase_HII PF01351.18 KUM62218.1 - 2.8e-47 161.1 0.0 3.7e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII Pex16 PF08610.10 KUM62219.1 - 2.5e-138 460.7 0.2 2.9e-138 460.5 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) SAE2 PF08573.10 KUM62220.1 - 5.9e-37 127.2 0.1 5.9e-37 127.2 0.1 3.8 5 1 0 5 5 5 1 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF3287 PF11690.8 KUM62220.1 - 0.033 13.9 1.2 0.09 12.5 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Histone_HNS PF00816.21 KUM62220.1 - 0.1 13.4 7.1 0.8 10.6 1.3 4.2 3 1 0 3 3 3 0 H-NS histone family bZIP_1 PF00170.21 KUM62220.1 - 0.21 11.7 5.9 0.24 11.5 0.9 3.0 2 1 1 3 3 3 0 bZIP transcription factor Fib_alpha PF08702.10 KUM62220.1 - 6 7.1 6.2 36 4.5 0.0 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family F-box PF00646.33 KUM62221.1 - 3e-07 30.2 0.6 3e-07 30.2 0.6 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KUM62221.1 - 2.8e-05 23.9 0.3 5.2e-05 23.1 0.3 1.5 1 0 0 1 1 1 1 F-box-like Sars6 PF12133.8 KUM62221.1 - 0.19 11.6 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus zf-CCHC PF00098.23 KUM62222.1 - 1.4e-50 167.2 63.6 2.3e-09 36.9 2.0 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KUM62222.1 - 2.1e-13 49.8 40.9 0.0056 16.4 0.7 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KUM62222.1 - 6.4e-06 26.0 53.7 0.0061 16.5 1.9 6.8 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 KUM62222.1 - 0.0002 21.0 43.6 0.63 9.8 0.5 7.1 5 2 2 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 KUM62222.1 - 0.00075 19.3 47.2 0.039 13.8 0.9 6.9 4 2 3 7 7 7 4 Zinc knuckle zf-CCHC_2 PF13696.6 KUM62222.1 - 0.012 15.4 1.5 0.012 15.4 1.5 7.4 7 0 0 7 7 7 0 Zinc knuckle UPF0061 PF02696.14 KUM62223.1 - 2.3e-129 432.2 0.0 2.9e-129 431.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family MA3 PF02847.17 KUM62223.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 MA3 domain Myb_DNA-binding PF00249.31 KUM62224.1 - 3.8e-14 52.6 1.9 9.5e-11 41.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KUM62224.1 - 9.7e-06 25.7 3.3 0.011 15.9 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain AGOG PF09171.10 KUM62224.1 - 0.13 11.6 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 N-glycosylase/DNA lyase Methyltransf_11 PF08241.12 KUM62225.1 - 5.7e-14 52.5 0.0 9.8e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM62225.1 - 2.8e-11 44.0 0.1 5.2e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM62225.1 - 1.2e-07 31.8 0.0 4.4e-07 29.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM62225.1 - 5.5e-06 27.1 0.1 9.8e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM62225.1 - 1.2e-05 25.2 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KUM62225.1 - 0.023 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 KUM62225.1 - 0.029 13.3 0.0 0.096 11.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Reprolysin_4 PF13583.6 KUM62227.1 - 1.8e-31 109.3 2.7 3.4e-31 108.5 2.7 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KUM62227.1 - 2e-28 99.9 4.2 3.8e-28 99.0 4.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KUM62227.1 - 1.4e-16 60.9 0.6 2.5e-16 60.2 0.6 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KUM62227.1 - 0.0011 19.5 0.4 0.0028 18.2 0.1 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KUM62227.1 - 0.0093 15.9 0.2 0.032 14.1 0.2 1.8 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease SPT16 PF08644.11 KUM62228.1 - 5.6e-56 188.9 0.0 1.5e-55 187.6 0.0 1.8 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KUM62228.1 - 5.9e-56 188.7 0.1 2.4e-55 186.7 0.1 2.2 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KUM62228.1 - 2.1e-28 99.4 0.0 3.7e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KUM62228.1 - 2.1e-14 53.7 0.2 5.2e-14 52.4 0.1 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Arc_PepC PF06819.11 KUM62228.1 - 0.032 14.3 0.5 2.8 8.1 0.0 3.1 3 0 0 3 3 3 0 Archaeal Peptidase A24 C-terminal Domain Choline_transpo PF04515.12 KUM62229.1 - 1.3e-22 80.5 19.2 1.3e-22 80.5 19.2 2.4 2 1 0 2 2 2 2 Plasma-membrane choline transporter Peptidase_M43 PF05572.13 KUM62230.1 - 6e-13 49.0 0.1 2.5e-12 47.0 0.1 2.0 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KUM62230.1 - 1.3e-05 25.5 5.1 3.1e-05 24.2 5.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KUM62230.1 - 0.016 15.7 0.2 0.037 14.5 0.2 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Mito_carr PF00153.27 KUM62231.1 - 2e-19 69.3 0.6 2e-13 50.1 0.1 2.8 2 1 0 2 2 2 2 Mitochondrial carrier protein Sugar_tr PF00083.24 KUM62233.1 - 1.4e-102 343.9 12.9 1.7e-102 343.6 12.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM62233.1 - 4.8e-29 101.4 30.4 7.3e-27 94.2 27.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KUM62233.1 - 9.1e-07 27.8 19.7 1.3e-05 24.0 7.5 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein INSIG PF07281.12 KUM62233.1 - 0.082 12.6 1.5 0.2 11.3 1.5 1.6 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) TB2_DP1_HVA22 PF03134.19 KUM62233.1 - 0.67 9.9 3.8 0.38 10.7 0.8 2.2 2 0 0 2 2 2 0 TB2/DP1, HVA22 family PMT PF02366.18 KUM62234.1 - 5.5e-89 298.0 14.4 5.5e-89 298.0 14.4 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KUM62234.1 - 6.5e-63 211.9 14.3 6.5e-63 211.9 14.3 2.5 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KUM62234.1 - 1e-36 126.5 0.2 1.7e-36 125.9 0.2 1.2 1 0 0 1 1 1 1 MIR domain Ras PF00071.22 KUM62235.1 - 1.8e-47 161.0 0.0 6e-37 126.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KUM62235.1 - 2.4e-28 98.8 0.0 1.7e-17 63.7 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM62235.1 - 2e-11 43.6 0.0 7.3e-11 41.8 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KUM62235.1 - 1.1e-08 34.9 0.0 2.5e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KUM62235.1 - 0.0004 20.4 0.0 0.0025 17.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KUM62235.1 - 0.00085 18.7 0.0 0.0027 17.1 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KUM62235.1 - 0.0058 16.6 0.0 0.93 9.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 KUM62235.1 - 0.0066 16.2 0.1 0.048 13.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KUM62235.1 - 0.0098 16.2 0.0 0.049 13.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain Flu_M1_C PF08289.11 KUM62235.1 - 0.035 14.3 0.1 0.057 13.6 0.1 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Aldo_ket_red PF00248.21 KUM62237.1 - 2.7e-42 145.0 0.0 9e-41 140.0 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Atg8 PF02991.16 KUM62238.1 - 2.7e-51 172.1 0.2 3.2e-51 171.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KUM62238.1 - 3e-06 27.5 0.0 3.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.18 KUM62239.1 - 3e-134 446.4 0.0 5.6e-134 445.5 0.0 1.4 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase HOOK PF05622.12 KUM62240.1 - 2.2e-26 92.3 66.3 1.5e-25 89.5 37.0 2.8 1 1 1 2 2 2 2 HOOK protein Spc7 PF08317.11 KUM62240.1 - 0.00088 18.2 74.0 0.099 11.5 8.4 4.9 3 1 2 5 5 5 4 Spc7 kinetochore protein KASH_CCD PF14662.6 KUM62240.1 - 0.013 15.4 81.3 0.12 12.1 18.1 5.1 3 1 2 5 5 5 0 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 KUM62240.1 - 0.013 15.5 6.0 0.013 15.5 6.0 6.9 5 3 2 7 7 7 0 TPR/MLP1/MLP2-like protein DUF1411 PF07199.11 KUM62240.1 - 0.056 13.1 4.3 0.13 12.0 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1411) HMMR_N PF15905.5 KUM62240.1 - 0.2 11.1 70.1 0.034 13.6 37.7 3.5 2 1 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 KUM62240.1 - 0.36 11.0 79.1 0.15 12.3 8.4 5.8 4 2 1 5 5 5 0 Autophagy protein 16 (ATG16) Csm1_N PF18504.1 KUM62240.1 - 0.71 10.3 56.4 2 8.8 4.6 7.6 6 1 0 7 7 7 0 Csm1 N-terminal domain Fib_alpha PF08702.10 KUM62240.1 - 1 9.6 54.0 0.11 12.7 7.4 5.4 3 2 2 5 5 5 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 KUM62240.1 - 5.5 7.0 78.1 0.15 12.2 6.5 5.8 3 1 2 6 6 6 0 Uncharacterised protein family (UPF0242) N-terminus HALZ PF02183.18 KUM62240.1 - 6.5 7.1 43.5 0.49 10.7 0.1 8.0 7 2 2 9 9 9 0 Homeobox associated leucine zipper Bacillus_HBL PF05791.11 KUM62240.1 - 7 6.4 40.8 0.1 12.5 4.9 5.8 4 2 1 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) DASH_Dad4 PF08650.10 KUM62240.1 - 7.7 6.6 10.4 1 9.4 0.3 4.5 5 1 1 6 6 6 0 DASH complex subunit Dad4 DUF4407 PF14362.6 KUM62240.1 - 9.8 5.4 55.9 0.63 9.3 10.5 4.2 1 1 1 2 2 1 0 Domain of unknown function (DUF4407) Mito_carr PF00153.27 KUM62241.1 - 3.1e-28 97.5 2.0 6.3e-15 54.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CFIA_Pcf11 PF11526.8 KUM62242.1 - 4.9e-08 33.4 0.3 4.9e-08 33.4 0.3 2.0 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 KUM62242.1 - 7e-06 26.8 0.0 1.9e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. GTPase_binding PF09027.10 KUM62242.1 - 0.099 12.6 0.5 0.66 10.0 0.1 2.5 2 0 0 2 2 2 0 GTPase binding VHS PF00790.19 KUM62242.1 - 0.12 12.2 0.0 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 VHS domain zf-ISL3 PF14690.6 KUM62242.1 - 0.2 12.3 1.6 0.27 11.9 0.3 1.8 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf_UBZ PF18439.1 KUM62242.1 - 0.37 10.4 4.7 1.2 8.8 0.6 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KUM62242.1 - 2.7 8.0 7.0 9.9 6.2 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type MctB PF11382.8 KUM62243.1 - 0.021 14.6 0.0 0.022 14.5 0.0 1.0 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Inhibitor_I9 PF05922.16 KUM62243.1 - 0.067 13.9 0.1 0.12 13.1 0.1 1.6 1 1 0 1 1 1 0 Peptidase inhibitor I9 ADK PF00406.22 KUM62244.1 - 4.4e-60 202.2 0.0 5.6e-60 201.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KUM62244.1 - 4.9e-23 82.0 0.2 1e-22 81.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KUM62244.1 - 1.5e-16 60.1 0.0 3.8e-16 58.8 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KUM62244.1 - 1.2e-07 32.3 0.0 2.5e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KUM62244.1 - 3.9e-05 23.8 0.0 7.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran_CTD PF16326.5 KUM62244.1 - 0.067 13.5 0.6 0.22 11.8 0.1 2.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain Thymidylate_kin PF02223.17 KUM62244.1 - 0.082 12.6 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase TSC22 PF01166.18 KUM62244.1 - 0.084 13.2 0.2 0.21 11.9 0.2 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family GFO_IDH_MocA PF01408.22 KUM62245.1 - 4.7e-17 62.9 0.1 6.6e-17 62.5 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KUM62245.1 - 0.0058 17.3 0.1 0.0096 16.6 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain UCH PF00443.29 KUM62246.1 - 1.9e-20 73.4 0.0 4.4e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KUM62246.1 - 1.1e-07 31.8 0.0 1.8e-06 27.8 0.0 2.1 1 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MitMem_reg PF13012.6 KUM62247.1 - 1.8e-37 128.2 0.3 3.1e-37 127.4 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KUM62247.1 - 6.6e-32 110.0 0.0 1.4e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease NARP1 PF12569.8 KUM62247.1 - 0.19 10.6 4.5 0.33 9.8 4.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 tRNA_bind_2 PF13725.6 KUM62247.1 - 0.27 10.9 4.4 0.39 10.4 4.4 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain CobT PF06213.12 KUM62247.1 - 1.3 8.3 8.9 1.9 7.8 8.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC50 PF03381.15 KUM62248.1 - 1.2e-95 320.2 0.1 1.5e-95 320.0 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3185 PF11381.8 KUM62248.1 - 2.1 8.4 5.4 0.73 9.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) GGACT PF06094.12 KUM62250.1 - 1.8e-13 51.2 0.0 2.1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like SWIRM PF04433.17 KUM62251.1 - 5.1e-12 46.0 0.0 1.1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain PRCC PF10253.9 KUM62251.1 - 8.4 7.1 7.4 4.3 8.1 2.4 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting PH PF00169.29 KUM62253.1 - 3.3e-06 27.6 0.2 1.4e-05 25.5 0.1 2.0 2 0 0 2 2 2 1 PH domain DUF3921 PF13060.6 KUM62253.1 - 0.027 14.5 0.0 0.07 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) DUF3632 PF12311.8 KUM62254.1 - 5.8e-19 69.2 11.5 8e-19 68.7 11.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) eIF3m_C_helix PF18005.1 KUM62254.1 - 0.082 12.6 0.2 0.082 12.6 0.2 2.1 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix DUF2370 PF10176.9 KUM62255.1 - 2.7e-92 308.5 0.2 6.7e-92 307.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) DUF2561 PF10812.8 KUM62255.1 - 0.095 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Pkinase PF00069.25 KUM62256.1 - 7.7e-68 228.7 0.0 1.2e-67 228.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM62256.1 - 2.2e-31 109.1 0.0 3.3e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KUM62256.1 - 0.013 14.4 0.0 0.024 13.6 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KUM62256.1 - 0.046 13.1 0.0 0.094 12.1 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KUM62256.1 - 0.046 13.6 0.3 0.17 11.8 0.0 2.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family UCH PF00443.29 KUM62258.1 - 1.6e-45 155.6 0.0 3.7e-45 154.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KUM62258.1 - 2.1e-44 149.2 0.6 3.2e-15 55.8 0.0 4.6 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.6 KUM62258.1 - 0.00023 20.9 0.1 0.0026 17.4 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase IES5 PF17335.2 KUM62258.1 - 0.0051 17.1 0.7 0.016 15.5 0.7 1.8 1 0 0 1 1 1 1 Ino80 complex subunit 5 LEDGF PF11467.8 KUM62258.1 - 0.036 13.7 0.1 0.11 12.1 0.1 1.8 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) DUF1451 PF07295.11 KUM62258.1 - 4.1 7.4 5.5 1 9.4 1.8 1.9 2 0 0 2 2 2 0 Zinc-ribbon containing domain Tim17 PF02466.19 KUM62259.1 - 2.6e-07 31.0 6.9 5.8e-07 29.9 6.5 1.9 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Na_H_antiport_3 PF07399.11 KUM62259.1 - 0.16 10.8 1.0 0.22 10.3 1.0 1.1 1 0 0 1 1 1 0 Putative Na+/H+ antiporter CoA_trans PF01144.23 KUM62261.1 - 6.5e-101 336.2 1.0 6.5e-61 205.5 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase tRNA-synt_2b PF00587.25 KUM62262.1 - 1.4e-28 100.1 0.0 4.9e-26 91.8 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KUM62262.1 - 1.1e-16 60.7 0.1 4.1e-16 58.9 0.1 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.14 KUM62262.1 - 3.3e-14 52.7 0.0 6.6e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KUM62262.1 - 0.00032 20.7 0.0 0.00079 19.4 0.0 1.7 1 0 0 1 1 1 1 TGS domain G_glu_transpept PF01019.21 KUM62263.1 - 7e-139 463.9 0.0 8.2e-139 463.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase HalOD2 PF18547.1 KUM62264.1 - 0.14 12.1 0.3 0.14 12.1 0.3 3.0 3 0 0 3 3 3 0 Halobacterial output domain 2 zf-piccolo PF05715.13 KUM62264.1 - 0.46 10.7 11.5 3.1 8.0 4.7 2.8 2 1 0 2 2 2 0 Piccolo Zn-finger FYVE_2 PF02318.16 KUM62264.1 - 1 9.6 6.9 0.88 9.8 1.4 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger Gar1 PF04410.14 KUM62266.1 - 3.6e-39 134.0 0.0 4.3e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.21 KUM62267.1 - 4.7e-12 46.5 0.7 1.4e-11 45.0 0.1 2.0 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Cation_efflux PF01545.21 KUM62267.1 - 0.078 12.7 2.9 2 8.1 0.1 2.1 2 0 0 2 2 2 0 Cation efflux family WSC PF01822.19 KUM62268.1 - 3e-11 43.3 9.9 3e-11 43.3 9.9 2.3 2 1 0 2 2 2 1 WSC domain SKG6 PF08693.10 KUM62268.1 - 1.5e-10 40.3 0.3 1.5e-10 40.3 0.3 2.7 3 0 0 3 3 3 1 Transmembrane alpha-helix domain GRA6 PF05084.13 KUM62268.1 - 0.0017 18.4 0.3 0.0022 18.0 0.3 1.1 1 0 0 1 1 1 1 Granule antigen protein (GRA6) TMEM154 PF15102.6 KUM62268.1 - 0.0025 17.7 0.1 0.0048 16.8 0.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF4366 PF14283.6 KUM62268.1 - 0.0055 16.8 0.3 0.0088 16.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Podoplanin PF05808.11 KUM62268.1 - 0.0065 16.6 6.4 0.0091 16.1 6.4 1.2 1 0 0 1 1 1 1 Podoplanin DUF2207 PF09972.9 KUM62268.1 - 0.0066 15.3 0.0 0.0084 14.9 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Dicty_REP PF05086.12 KUM62268.1 - 0.024 12.7 1.0 0.026 12.5 1.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2165 PF09933.9 KUM62268.1 - 0.053 13.5 0.3 0.087 12.9 0.3 1.3 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) DUF2370 PF10176.9 KUM62268.1 - 0.056 13.1 0.1 0.084 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Mucin PF01456.17 KUM62268.1 - 0.23 11.5 19.1 0.4 10.7 19.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SprA-related PF12118.8 KUM62268.1 - 1.1 8.3 11.8 1.5 7.9 11.8 1.2 1 0 0 1 1 1 0 SprA-related family zf-C2H2 PF00096.26 KUM62269.1 - 0.0012 19.2 1.0 0.0012 19.2 1.0 2.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type COQ9 PF08511.11 KUM62270.1 - 8.5e-23 79.9 0.2 1.5e-22 79.1 0.2 1.4 1 0 0 1 1 1 1 COQ9 RRM_1 PF00076.22 KUM62271.1 - 5.4e-41 138.3 0.0 4.8e-17 61.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KUM62271.1 - 0.00016 21.3 0.0 0.018 14.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PknH_C PF14032.6 KUM62271.1 - 0.0011 18.9 3.5 7.5 6.4 0.1 3.2 3 0 0 3 3 3 3 PknH-like extracellular domain Limkain-b1 PF11608.8 KUM62271.1 - 0.0014 18.7 0.4 15 5.7 0.0 4.4 3 2 0 3 3 3 1 Limkain b1 ATP-grasp_2 PF08442.10 KUM62271.1 - 0.14 11.7 0.0 0.61 9.6 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain Glyco_hydro_47 PF01532.20 KUM62272.1 - 7e-180 598.8 0.0 8.3e-180 598.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 4HB_MCP_1 PF12729.7 KUM62272.1 - 0.17 11.4 0.1 0.32 10.5 0.1 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF2013 PF09431.10 KUM62273.1 - 4e-51 172.8 3.2 5.1e-51 172.5 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) APG9 PF04109.16 KUM62274.1 - 8.6e-210 697.7 11.7 1e-209 697.5 11.7 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Ifi-6-16 PF06140.13 KUM62275.1 - 0.00011 22.1 0.1 0.00027 20.8 0.0 1.6 2 0 0 2 2 2 1 Interferon-induced 6-16 family DUF4404 PF14357.6 KUM62275.1 - 0.00046 20.8 0.0 0.0006 20.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4404) Nop14 PF04147.12 KUM62276.1 - 0.087 11.0 12.2 0.11 10.7 12.2 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KUM62276.1 - 3.5 7.0 17.1 4.8 6.5 17.1 1.1 1 0 0 1 1 1 0 SDA1 Sas10_Utp3 PF04000.15 KUM62277.1 - 1.3e-17 64.2 0.4 1.3e-17 64.2 0.4 1.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family TT_ORF2 PF02957.15 KUM62277.1 - 0.31 12.0 9.8 0.14 13.1 2.9 2.6 2 0 0 2 2 2 0 TT viral ORF2 UQ_con PF00179.26 KUM62279.1 - 3.4e-44 149.9 0.0 3.9e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RVT_2 PF07727.14 KUM62280.1 - 1.1e-26 93.9 0.0 2.7e-26 92.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KUM62280.1 - 0.00063 19.3 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mito_carr PF00153.27 KUM62281.1 - 4.1e-58 193.3 5.5 6.4e-19 67.7 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4653 PF15546.6 KUM62281.1 - 1.8 8.1 8.1 3.1 7.3 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) EF-hand_1 PF00036.32 KUM62282.1 - 5.2e-26 88.2 11.2 3.9e-08 32.3 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KUM62282.1 - 2.7e-25 86.1 5.5 3.8e-06 26.4 0.1 5.2 4 1 1 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 KUM62282.1 - 2.8e-24 85.3 7.8 1e-15 57.9 0.9 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KUM62282.1 - 7.8e-17 59.9 12.3 0.00017 21.0 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 KUM62282.1 - 9.6e-16 57.4 11.2 5.2e-06 26.2 1.1 4.1 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KUM62282.1 - 6e-09 35.8 5.6 0.0027 17.6 0.1 3.6 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KUM62282.1 - 0.00018 21.8 0.7 0.024 14.9 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain EF-hand_10 PF14788.6 KUM62282.1 - 0.0021 17.9 1.0 0.51 10.2 0.1 3.5 3 1 0 3 3 3 1 EF hand DUF1679 PF07914.11 KUM62282.1 - 0.019 13.9 0.3 1.4 7.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) SPARC_Ca_bdg PF10591.9 KUM62282.1 - 0.028 14.7 1.8 2.3 8.6 0.3 3.2 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TFIIIC_delta PF12657.7 KUM62283.1 - 1.7e-21 77.0 0.2 4.1e-21 75.7 0.2 1.7 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KUM62283.1 - 4.4e-09 36.2 0.1 9.4e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex PALP PF00291.25 KUM62283.1 - 0.2 11.0 0.1 0.32 10.3 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Thiolase_N PF00108.23 KUM62284.1 - 5.2e-90 301.3 0.6 1e-89 300.4 0.6 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KUM62284.1 - 1.1e-38 131.7 1.2 1.1e-38 131.7 1.2 2.0 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KUM62284.1 - 3.2e-05 23.6 1.9 3.2e-05 23.6 1.9 2.3 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KUM62284.1 - 3.5 7.6 6.7 5.3 7.0 0.2 3.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.26 KUM62285.1 - 1e-51 174.3 0.0 1.1e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KUM62285.1 - 0.0019 17.9 0.0 0.0022 17.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KUM62285.1 - 0.087 13.1 0.0 0.18 12.1 0.0 1.5 1 1 0 1 1 1 0 RWD domain Aminotran_1_2 PF00155.21 KUM62286.1 - 7e-61 206.4 0.0 8.4e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II YjfB_motility PF14070.6 KUM62286.1 - 0.15 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative motility protein Aa_trans PF01490.18 KUM62287.1 - 1.7e-47 162.0 35.5 2e-47 161.8 35.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DHDPS PF00701.22 KUM62288.1 - 1.5e-37 128.9 0.1 1.8e-37 128.6 0.1 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family TPR_3 PF07720.12 KUM62288.1 - 0.072 13.1 0.3 0.25 11.4 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 KUM62288.1 - 0.12 12.3 0.3 5 7.1 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat NAD_binding_4 PF07993.12 KUM62289.1 - 2.5e-38 131.7 0.0 3.1e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KUM62289.1 - 0.0011 18.2 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KUM62289.1 - 0.0074 15.8 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.8 KUM62290.1 - 0.071 11.9 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Cation_efflux PF01545.21 KUM62291.1 - 6.9e-46 156.5 12.7 6.9e-46 156.5 12.7 2.8 2 1 0 2 2 2 1 Cation efflux family Glyco_trans_1_4 PF13692.6 KUM62292.1 - 9.8e-10 39.0 0.0 5.1e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KUM62292.1 - 3.7e-05 23.8 0.0 8.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KUM62292.1 - 0.0001 21.9 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KUM62292.1 - 0.0089 16.4 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KUM62292.1 - 0.074 13.5 0.0 0.25 11.8 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain RMI1_N PF08585.12 KUM62292.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 RecQ mediated genome instability protein ABC_membrane PF00664.23 KUM62293.1 - 3e-89 299.3 30.5 5.6e-46 157.4 16.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KUM62293.1 - 2.6e-54 183.4 0.0 3.5e-33 115.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KUM62293.1 - 1.8e-12 47.2 0.3 9.8e-06 25.2 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KUM62293.1 - 3.4e-09 37.5 1.1 0.002 18.6 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KUM62293.1 - 5.4e-09 35.7 0.7 0.0006 19.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KUM62293.1 - 6.8e-09 36.1 0.0 0.0045 17.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KUM62293.1 - 2.1e-08 34.8 0.1 0.015 15.7 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KUM62293.1 - 4e-08 33.4 0.0 0.00067 19.5 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KUM62293.1 - 2.4e-07 30.8 0.0 0.032 14.1 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KUM62293.1 - 1.2e-06 28.6 0.0 0.0099 15.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KUM62293.1 - 1.4e-05 25.1 0.0 0.025 14.5 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_18 PF13238.6 KUM62293.1 - 2.2e-05 25.0 0.0 0.23 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KUM62293.1 - 9.1e-05 22.6 0.0 0.3 11.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KUM62293.1 - 0.0001 22.3 0.0 0.41 10.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 KUM62293.1 - 0.00024 20.0 3.9 0.086 11.6 0.1 3.6 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_30 PF13604.6 KUM62293.1 - 0.00025 20.8 0.0 0.61 9.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 KUM62293.1 - 0.00033 21.0 0.0 0.43 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KUM62293.1 - 0.00033 20.2 0.0 0.52 9.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 KUM62293.1 - 0.00047 19.8 0.0 0.29 10.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KUM62293.1 - 0.00087 19.1 0.1 2.6 7.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KUM62293.1 - 0.001 19.5 0.2 1.5 9.3 0.0 3.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 KUM62293.1 - 0.0012 18.1 0.0 0.92 8.6 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit Zeta_toxin PF06414.12 KUM62293.1 - 0.0043 16.4 0.1 4.1 6.6 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin PRK PF00485.18 KUM62293.1 - 0.0046 16.7 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 KUM62293.1 - 0.0049 17.2 0.0 2.3 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase DUF87 PF01935.17 KUM62293.1 - 0.0049 17.0 0.6 3.7 7.6 0.0 2.9 3 0 0 3 3 3 1 Helicase HerA, central domain NB-ARC PF00931.22 KUM62293.1 - 0.0051 16.0 0.0 0.82 8.8 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Cytidylate_kin PF02224.18 KUM62293.1 - 0.0093 15.7 0.0 4 7.1 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase MMR_HSR1 PF01926.23 KUM62293.1 - 0.017 15.2 0.1 7.3 6.7 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 KUM62293.1 - 0.019 15.0 0.0 2.6 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KUM62293.1 - 0.044 13.7 0.0 15 5.5 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase IstB_IS21 PF01695.17 KUM62293.1 - 0.057 13.1 0.2 6.2 6.5 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein KAP_NTPase PF07693.14 KUM62293.1 - 0.058 12.6 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain TniB PF05621.11 KUM62293.1 - 0.063 12.7 0.0 22 4.4 0.0 3.0 3 0 0 3 3 3 0 Bacterial TniB protein AAA_17 PF13207.6 KUM62293.1 - 0.09 13.2 0.0 16 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KUM62293.1 - 0.094 12.1 0.0 6.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 KUM62293.1 - 0.13 12.0 0.0 7.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KUM62293.1 - 0.16 11.8 0.2 49 3.8 0.0 3.2 3 0 0 3 3 3 0 NTPase ATP-synt_ab PF00006.25 KUM62293.1 - 0.27 10.9 1.3 14 5.3 1.2 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RTA1 PF04479.13 KUM62294.1 - 1.5e-71 240.2 5.9 2e-71 239.9 5.9 1.1 1 0 0 1 1 1 1 RTA1 like protein DctQ PF04290.12 KUM62294.1 - 0.01 15.8 0.8 0.01 15.8 0.8 2.6 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component PhrC_PhrF PF11131.8 KUM62294.1 - 0.1 12.2 0.4 0.1 12.2 0.4 2.0 2 0 0 2 2 2 0 Rap-phr extracellular signalling Chitin_synth_1 PF01644.17 KUM62295.1 - 1.1e-23 84.0 0.1 1.7e-23 83.4 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KUM62295.1 - 1.7e-22 79.8 0.1 9.8e-20 70.7 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KUM62295.1 - 3.6e-10 40.1 0.1 3.6e-10 40.1 0.1 2.8 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KUM62295.1 - 0.0051 16.7 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 adh_short PF00106.25 KUM62296.1 - 2.6e-19 69.5 0.0 3.6e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM62296.1 - 5.6e-17 62.1 0.0 7.5e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ULD PF16534.5 KUM62296.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like oligomerisation domain of SATB MFS_1 PF07690.16 KUM62297.1 - 6.3e-37 127.3 44.8 6.3e-37 127.3 44.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily FMN_dh PF01070.18 KUM62298.1 - 3.2e-110 368.5 0.0 3.6e-110 368.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KUM62298.1 - 2.5e-05 23.6 0.0 3.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KUM62298.1 - 0.0015 18.0 0.1 0.0025 17.2 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KUM62298.1 - 0.0058 15.7 1.0 0.01 14.9 0.2 1.8 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KUM62298.1 - 0.15 11.5 0.0 8 5.8 0.0 2.3 2 0 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 KUM62298.1 - 0.2 11.0 0.0 20 4.4 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Hydantoinase_B PF02538.14 KUM62299.1 - 1.6e-217 723.1 0.1 2e-217 722.7 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KUM62299.1 - 1.3e-102 343.0 0.1 6.3e-101 337.5 0.0 2.2 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KUM62299.1 - 2.7e-58 196.6 0.0 6.5e-55 185.6 0.0 2.8 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Fungal_trans PF04082.18 KUM62300.1 - 4.5e-19 68.5 0.1 9.4e-19 67.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyclase PF04199.13 KUM62300.1 - 1.3e-13 51.3 0.0 2.7e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Putative cyclase Zn_clus PF00172.18 KUM62300.1 - 6.6e-08 32.5 8.8 1.3e-07 31.6 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N_2 PF16884.5 KUM62300.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Chitin_synth_1N PF08407.11 KUM62301.1 - 3.2e-28 97.5 0.1 5e-28 96.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_1 PF01644.17 KUM62301.1 - 4.9e-28 98.1 0.0 6.8e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase FMO-like PF00743.19 KUM62302.1 - 3.5e-18 65.3 0.0 5.5e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KUM62302.1 - 4.4e-12 45.9 0.0 1.3e-11 44.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM62302.1 - 4.2e-10 39.3 0.0 6.8e-09 35.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KUM62302.1 - 2.2e-05 23.9 0.0 0.0077 15.5 0.0 1.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM62302.1 - 0.037 14.6 0.5 0.087 13.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KUM62302.1 - 0.052 14.0 0.0 0.088 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KUM62302.1 - 0.1 12.6 0.2 9.1 6.2 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_4 PF01565.23 KUM62303.1 - 6.2e-13 48.7 0.0 9.9e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Kinesin PF00225.23 KUM62305.1 - 2e-111 372.1 0.0 4.7e-111 370.9 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KUM62305.1 - 2.6e-25 89.1 0.0 9.5e-25 87.3 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding STPPase_N PF16891.5 KUM62305.1 - 0.026 14.9 1.8 8.4 6.9 0.1 3.1 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain DUF1398 PF07166.11 KUM62305.1 - 0.059 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) DUF3577 PF12101.8 KUM62305.1 - 0.084 12.7 0.2 0.4 10.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3577) Filament PF00038.21 KUM62305.1 - 0.85 9.1 59.3 11 5.5 14.9 4.5 2 1 1 3 3 3 0 Intermediate filament protein XkdW PF09636.10 KUM62305.1 - 1.6 8.8 6.3 12 6.1 0.3 3.2 2 0 0 2 2 2 0 XkdW protein HAP1_N PF04849.13 KUM62305.1 - 6.5 5.9 53.4 1.9 7.6 13.2 4.0 3 2 0 3 3 3 0 HAP1 N-terminal conserved region EMP70 PF02990.16 KUM62306.1 - 9.6e-205 681.1 0.1 1.4e-204 680.7 0.1 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 5_nucleotid_C PF02872.18 KUM62308.1 - 4.2e-35 121.3 0.0 8.1e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KUM62308.1 - 1.3e-05 25.8 0.3 2.4e-05 24.9 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TFIIIC_delta PF12657.7 KUM62309.1 - 5.1e-06 26.5 0.2 7e-06 26.1 0.2 1.2 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term PD40 PF07676.12 KUM62309.1 - 0.11 12.5 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat TPR_12 PF13424.6 KUM62312.1 - 7.7e-41 138.3 0.0 3e-12 46.6 0.0 5.6 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KUM62312.1 - 8.4e-41 136.8 0.0 2.9e-09 36.5 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KUM62312.1 - 3.2e-15 54.9 0.0 0.035 14.1 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.22 KUM62312.1 - 2.7e-10 39.9 0.1 1.3e-09 37.7 0.0 2.0 2 1 1 3 3 3 1 NB-ARC domain NACHT PF05729.12 KUM62312.1 - 0.00013 22.0 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Ses_B PF17046.5 KUM62312.1 - 0.00025 20.9 1.2 0.00054 19.8 1.2 1.6 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein TPR_17 PF13431.6 KUM62312.1 - 0.00053 20.2 0.0 22 5.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KUM62312.1 - 0.0011 19.6 0.0 13 6.5 0.0 3.8 2 1 2 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KUM62312.1 - 0.0012 18.6 0.0 46 4.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat N36 PF11438.8 KUM62312.1 - 0.0068 16.2 4.2 29 4.6 0.0 4.5 5 0 0 5 5 5 0 36-mer N-terminal peptide of the N protein (N36) AAA_16 PF13191.6 KUM62312.1 - 0.014 15.8 0.1 0.043 14.2 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KUM62312.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KUM62312.1 - 0.038 14.2 0.0 0.14 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain DNA_pol_A_exoN PF18305.1 KUM62312.1 - 0.083 13.2 1.4 68 3.8 0.1 3.6 2 1 1 3 3 3 0 3' to 5' exonuclease C-terminal domain AAA_5 PF07728.14 KUM62312.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Helo_like_N PF17111.5 KUM62313.1 - 7.7e-20 71.2 3.5 1e-19 70.8 3.5 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ses_B PF17046.5 KUM62313.1 - 0.0024 17.8 0.8 0.0036 17.2 0.8 1.3 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein MWFE PF15879.5 KUM62313.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit DUF4637 PF15470.6 KUM62313.1 - 0.53 10.0 6.4 1.3 8.7 6.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) I_LWEQ PF01608.17 KUM62313.1 - 0.77 10.0 11.5 0.3 11.3 7.2 2.1 1 1 1 2 2 2 0 I/LWEQ domain tRNA_m1G_MT PF01746.21 KUM62314.1 - 5.5e-25 88.2 0.0 3.5e-24 85.6 0.0 2.1 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase VID27 PF08553.10 KUM62315.1 - 3e-194 644.9 0.2 4.2e-194 644.5 0.2 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KUM62315.1 - 7.7e-75 250.5 0.1 7.7e-75 250.5 0.1 2.8 3 1 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 KUM62315.1 - 2e-47 159.9 2.6 7.7e-47 158.1 1.9 2.2 2 0 0 2 2 2 1 VID27 PH-like domain UPF0149 PF03695.13 KUM62315.1 - 0.021 15.1 4.1 0.047 14.0 3.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) Dynamin_M PF01031.20 KUM62316.1 - 2.1e-18 66.6 0.1 3.3e-17 62.6 0.0 2.6 2 1 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KUM62316.1 - 6e-10 39.4 0.0 1.4e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MnmE_helical PF12631.7 KUM62316.1 - 0.064 13.4 0.2 0.17 12.1 0.2 1.6 1 0 0 1 1 1 0 MnmE helical domain bPH_6 PF10756.9 KUM62316.1 - 0.074 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Bacterial PH domain JIP_LZII PF16471.5 KUM62316.1 - 0.21 11.8 0.5 0.58 10.4 0.1 1.9 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II TLD PF07534.16 KUM62317.1 - 6.8e-25 87.9 0.0 1.6e-14 54.3 0.0 2.2 2 0 0 2 2 2 2 TLD COA2 PF17051.5 KUM62318.1 - 0.001 19.0 11.9 0.17 12.0 1.1 3.2 1 1 2 3 3 3 3 Cytochrome C oxidase assembly factor 2 Neuropep_like PF15161.6 KUM62318.1 - 0.074 12.7 11.5 5.6 6.7 0.3 3.7 1 1 2 3 3 3 0 Neuropeptide-like TBCC PF07986.12 KUM62320.1 - 1.7e-32 111.7 0.3 2.6e-32 111.1 0.3 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KUM62320.1 - 1.4e-06 28.7 0.2 2.5e-06 27.9 0.2 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain RTX PF02382.15 KUM62320.1 - 0.089 12.5 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein Pro-kuma_activ PF09286.11 KUM62321.1 - 6e-22 78.5 0.8 1.6e-21 77.1 0.0 2.2 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KUM62321.1 - 0.0004 19.7 0.1 0.0006 19.2 0.1 1.4 1 0 0 1 1 1 1 Subtilase family DUF5390 PF17365.2 KUM62321.1 - 0.13 12.6 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5390) CSN8_PSD8_EIF3K PF10075.9 KUM62322.1 - 1.2e-18 67.5 0.0 1.9e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DEK_C PF08766.11 KUM62323.1 - 0.0012 18.7 0.0 0.0033 17.3 0.0 1.7 1 0 0 1 1 1 1 DEK C terminal domain Evr1_Alr PF04777.13 KUM62324.1 - 6.3e-27 94.0 6.1 6.3e-27 94.0 6.1 1.7 2 0 0 2 2 2 1 Erv1 / Alr family ANAPC1 PF12859.7 KUM62324.1 - 3.8 8.1 10.2 0.31 11.6 4.5 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 1 Coatomer_WDAD PF04053.14 KUM62325.1 - 7.7e-149 496.5 0.0 2.5e-148 494.9 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 KUM62325.1 - 2.6e-107 359.1 0.0 3.7e-107 358.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KUM62325.1 - 3.4e-38 129.0 13.2 3.7e-08 33.9 0.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM62325.1 - 1.4e-06 28.5 0.5 11 6.4 0.0 6.2 3 3 5 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KUM62325.1 - 0.043 12.4 7.9 4.8 5.7 0.2 4.0 3 1 1 4 4 4 0 Nucleoporin Nup120/160 SDA1 PF05285.12 KUM62325.1 - 5.4 6.3 7.3 9.9 5.5 7.3 1.3 1 0 0 1 1 1 0 SDA1 MFS_1 PF07690.16 KUM62328.1 - 1.6e-40 139.2 25.5 1.5e-35 122.8 16.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KUM62328.1 - 7.7e-06 25.4 15.6 0.00063 19.1 7.5 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KUM62328.1 - 1.2e-05 23.9 5.8 4.3e-05 22.0 1.5 2.7 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KUM62328.1 - 0.00038 19.4 13.3 0.18 10.7 10.2 3.7 3 1 0 3 3 3 2 MFS_1 like family UNC-93 PF05978.16 KUM62328.1 - 0.35 10.6 7.7 0.64 9.7 2.9 3.0 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 GRIM-19 PF06212.12 KUM62329.1 - 2.3e-23 82.6 0.4 7.4e-23 81.0 0.4 1.7 1 1 0 1 1 1 1 GRIM-19 protein EHN PF06441.12 KUM62331.1 - 1.2e-31 109.3 0.0 2.1e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KUM62331.1 - 1.7e-12 47.5 0.1 3e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KUM62331.1 - 0.01 16.4 6.8 0.034 14.7 6.8 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family DIOX_N PF14226.6 KUM62332.1 - 4.7e-34 117.7 0.0 7.8e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KUM62332.1 - 5e-21 75.1 0.0 9.3e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Vps51 PF08700.11 KUM62333.1 - 4.2e-27 94.0 0.0 8.9e-27 93.0 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 KUM62333.1 - 0.02 15.0 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Dor1 PF04124.12 KUM62333.1 - 0.11 11.2 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Dor1-like family DUF1917 PF08939.10 KUM62334.1 - 1.5e-86 290.5 0.0 1.7e-86 290.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) TPR_16 PF13432.6 KUM62335.1 - 3.3e-23 82.1 56.4 3.4e-06 27.6 2.8 11.4 12 2 3 15 15 12 7 Tetratricopeptide repeat TPR_14 PF13428.6 KUM62335.1 - 6.2e-23 79.5 46.5 1.8e-05 25.2 0.2 15.3 11 4 5 16 16 15 5 Tetratricopeptide repeat TPR_17 PF13431.6 KUM62335.1 - 2.2e-21 74.6 11.7 0.28 11.6 0.0 13.1 13 1 1 14 14 14 5 Tetratricopeptide repeat TPR_2 PF07719.17 KUM62335.1 - 1.9e-20 71.2 49.2 0.0009 19.2 0.1 15.0 16 0 0 16 16 15 5 Tetratricopeptide repeat TPR_1 PF00515.28 KUM62335.1 - 6.4e-19 66.9 37.1 0.00078 19.2 0.0 12.0 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_19 PF14559.6 KUM62335.1 - 1.1e-18 67.5 28.0 0.00029 21.3 0.6 9.8 8 1 2 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 KUM62335.1 - 3e-18 64.4 36.6 0.0034 17.5 0.0 12.7 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_11 PF13414.6 KUM62335.1 - 2.5e-14 52.7 14.4 0.039 13.6 0.1 8.7 7 1 1 8 8 8 4 TPR repeat TPR_6 PF13174.6 KUM62335.1 - 7.4e-12 45.1 24.1 0.00022 21.6 0.1 11.6 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_12 PF13424.6 KUM62335.1 - 3.8e-11 43.1 39.0 3.7e-06 27.1 1.5 11.4 12 1 1 13 13 13 4 Tetratricopeptide repeat TPR_7 PF13176.6 KUM62335.1 - 3.6e-08 32.9 21.9 0.0074 16.2 0.1 9.6 10 1 1 11 11 10 3 Tetratricopeptide repeat TPR_22 PF18833.1 KUM62335.1 - 5.3e-06 26.5 0.0 1.4e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM62335.1 - 0.00038 20.6 19.5 0.051 13.8 0.7 6.3 5 2 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KUM62335.1 - 0.024 14.8 23.4 0.045 13.9 0.2 6.4 6 2 1 7 7 5 0 Tetratricopeptide repeat ChAPs PF09295.10 KUM62335.1 - 0.027 13.5 3.9 13 4.6 0.1 4.9 6 1 1 7 7 7 0 ChAPs (Chs5p-Arf1p-binding proteins) HrpB1_HrpK PF09613.10 KUM62335.1 - 0.098 12.3 0.8 9 6.0 0.2 3.0 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) RMI1_N PF08585.12 KUM62336.1 - 1.2e-61 208.2 0.0 1.4e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein Xpo1 PF08389.12 KUM62337.1 - 2.7e-11 43.7 2.7 1.4e-05 25.2 0.0 3.6 4 0 0 4 4 4 2 Exportin 1-like protein IBN_N PF03810.19 KUM62337.1 - 0.021 14.7 1.4 0.34 10.8 0.1 3.8 4 1 1 5 5 5 0 Importin-beta N-terminal domain HEAT_2 PF13646.6 KUM62337.1 - 0.05 14.0 0.3 0.39 11.1 0.1 2.7 2 0 0 2 2 2 0 HEAT repeats CCDC24 PF15669.5 KUM62337.1 - 0.13 12.2 0.0 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family ACOX PF01756.19 KUM62337.1 - 0.13 11.8 0.1 15 5.1 0.1 2.6 2 0 0 2 2 2 0 Acyl-CoA oxidase Glyco_hydro_5_C PF18564.1 KUM62338.1 - 6e-22 78.0 0.0 1.4e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KUM62338.1 - 1.5e-07 31.1 6.6 1.2e-06 28.2 3.9 2.7 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) EKLF_TAD1 PF16832.5 KUM62338.1 - 0.062 13.2 0.9 0.17 11.8 0.9 1.7 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 DUF5310 PF17237.2 KUM62339.1 - 6.2e-21 74.0 1.0 6.2e-21 74.0 1.0 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5310) LRR_4 PF12799.7 KUM62339.1 - 0.0046 17.4 0.0 0.0084 16.5 0.0 1.4 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) EntA_Immun PF08951.10 KUM62339.1 - 0.043 14.2 0.1 0.053 13.9 0.1 1.1 1 0 0 1 1 1 0 Enterocin A Immunity DUF1184 PF06683.11 KUM62339.1 - 0.073 12.6 0.0 0.077 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) Adaptin_N PF01602.20 KUM62340.1 - 6e-139 464.0 2.8 7.8e-139 463.6 2.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KUM62340.1 - 1.5e-64 216.9 0.4 7e-60 201.7 0.2 2.6 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KUM62340.1 - 7.3e-17 61.5 4.0 3.9e-06 27.1 0.0 6.3 3 2 4 7 7 7 4 HEAT repeats HEAT PF02985.22 KUM62340.1 - 2.2e-12 46.1 2.8 0.023 14.9 0.0 6.9 7 0 0 7 7 6 2 HEAT repeat CLASP_N PF12348.8 KUM62340.1 - 0.0001 21.9 0.9 0.34 10.4 0.0 4.3 3 1 1 4 4 4 2 CLASP N terminal Arm PF00514.23 KUM62340.1 - 0.0012 18.8 1.4 12 6.1 0.0 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF2817 PF10994.8 KUM62340.1 - 0.0034 16.8 0.1 0.0062 16.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) RTP1_C1 PF10363.9 KUM62340.1 - 0.016 15.4 0.5 6.1 7.1 0.0 4.1 3 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KUM62340.1 - 0.034 14.6 8.8 0.39 11.3 0.0 5.8 7 1 1 8 8 7 0 HEAT-like repeat CAAP1 PF15335.6 KUM62340.1 - 0.38 11.3 2.9 0.41 11.2 0.1 2.5 3 0 0 3 3 2 0 Caspase activity and apoptosis inhibitor 1 DUF5578 PF17741.1 KUM62340.1 - 4 6.8 6.5 37 3.6 0.2 3.7 2 1 3 5 5 5 0 Family of unknown function (DUF5578) Thr_synth_N PF14821.6 KUM62341.1 - 4.4e-29 100.5 0.0 1.4e-28 98.9 0.0 1.9 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 KUM62341.1 - 4.3e-13 49.3 0.0 2.1e-12 47.1 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Sugar_tr PF00083.24 KUM62342.1 - 1.9e-77 261.0 24.4 2.4e-77 260.7 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM62342.1 - 5.7e-17 61.7 54.8 5.1e-14 52.0 26.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DHR-2 PF06920.13 KUM62342.1 - 0.12 11.0 0.2 0.16 10.5 0.2 1.1 1 0 0 1 1 1 0 Dock homology region 2 DUF2456 PF10445.9 KUM62342.1 - 0.37 10.9 6.2 2.5 8.2 1.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) NmrA PF05368.13 KUM62343.1 - 9.7e-12 44.9 0.2 2.1e-06 27.5 0.2 2.1 1 1 1 2 2 2 2 NmrA-like family Profilin PF00235.19 KUM62344.1 - 6.7e-39 133.1 0.1 7.3e-39 132.9 0.1 1.0 1 0 0 1 1 1 1 Profilin ADH_N PF08240.12 KUM62345.1 - 3.3e-25 88.1 5.4 5.6e-25 87.3 5.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM62345.1 - 7.4e-17 61.5 0.0 1.3e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM62345.1 - 6.2e-09 37.0 0.0 9.6e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KUM62345.1 - 0.0064 15.9 0.0 0.0091 15.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KUM62345.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_4 PF01565.23 KUM62346.1 - 1.5e-21 76.6 0.6 2.7e-21 75.8 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KUM62346.1 - 1.5e-09 37.8 1.9 3.1e-09 36.8 1.9 1.5 1 0 0 1 1 1 1 Berberine and berberine like Rick_17kDa_Anti PF05433.15 KUM62347.1 - 0.0014 18.4 16.9 0.0014 18.4 16.9 2.1 2 0 0 2 2 2 1 Glycine zipper 2TM domain DUF533 PF04391.12 KUM62347.1 - 0.0044 16.6 6.6 0.0062 16.1 6.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF533) MarC PF01914.17 KUM62347.1 - 0.015 14.7 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 MarC family integral membrane protein PCO_ADO PF07847.12 KUM62347.1 - 0.021 14.3 0.9 0.27 10.7 0.1 2.0 2 0 0 2 2 2 0 PCO_ADO SUIM_assoc PF16619.5 KUM62347.1 - 0.03 14.4 6.0 0.03 14.4 6.0 1.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF1294 PF06961.13 KUM62347.1 - 0.38 11.0 2.2 5.7 7.3 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) ABC_tran PF00005.27 KUM62349.1 - 1.2e-50 171.5 0.0 1.1e-30 106.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KUM62349.1 - 2.2e-37 129.2 32.2 9.5e-25 87.8 9.1 3.1 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KUM62349.1 - 1.7e-07 30.9 5.0 0.19 11.1 0.1 4.3 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KUM62349.1 - 0.00035 20.2 2.3 0.54 10.0 0.5 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KUM62349.1 - 0.00072 19.2 0.1 0.57 9.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KUM62349.1 - 0.0008 19.6 1.4 0.15 12.2 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 KUM62349.1 - 0.00084 18.5 0.5 0.075 12.1 0.2 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 KUM62349.1 - 0.0012 19.4 0.2 0.35 11.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KUM62349.1 - 0.0024 18.0 0.5 0.35 10.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KUM62349.1 - 0.0044 16.3 0.2 1.4 8.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 KUM62349.1 - 0.0057 16.6 0.6 1.3 8.9 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KUM62349.1 - 0.0091 16.4 3.6 0.61 10.4 0.1 3.5 3 1 0 3 3 3 1 AAA ATPase domain DUF2075 PF09848.9 KUM62349.1 - 0.0098 15.2 1.0 0.48 9.6 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KUM62349.1 - 0.022 15.0 1.8 5.5 7.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 KUM62349.1 - 0.042 14.1 0.0 17 5.7 0.0 3.6 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 KUM62349.1 - 0.11 11.7 0.2 8.3 5.5 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain AAA_21 PF13304.6 KUM62349.1 - 0.13 12.1 3.0 22 4.7 0.1 3.8 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 KUM62349.1 - 0.16 11.7 0.1 0.46 10.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KUM62349.1 - 0.16 11.3 0.2 11 5.3 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 KUM62349.1 - 0.3 11.0 4.8 11 6.0 0.1 3.5 3 0 0 3 3 3 0 NACHT domain p450 PF00067.22 KUM62350.1 - 1.1e-50 172.8 0.0 1.4e-50 172.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 P5CR_dimer PF14748.6 KUM62351.1 - 5.2e-28 97.3 0.5 9.4e-28 96.5 0.5 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KUM62351.1 - 2.7e-07 31.1 0.0 4e-05 24.1 0.0 3.1 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Sgf11_N PF18519.1 KUM62351.1 - 0.57 9.8 2.5 0.33 10.5 0.3 1.8 2 0 0 2 2 2 0 SAGA-associated factor 11 N-terminal domain AMP-binding PF00501.28 KUM62352.1 - 0 1041.7 0.0 4.1e-68 229.9 0.0 5.2 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.20 KUM62352.1 - 1.8e-198 659.9 0.0 7.2e-44 150.2 0.0 5.7 5 1 0 5 5 5 5 Condensation domain PP-binding PF00550.25 KUM62352.1 - 1.5e-51 172.6 12.8 2e-11 44.0 0.1 6.5 7 0 0 7 7 7 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM62352.1 - 2.5e-09 38.0 0.0 0.17 12.9 0.0 5.0 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 KUM62352.1 - 0.0041 16.9 0.1 16 5.2 0.0 4.5 5 0 0 5 5 5 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Transferase PF02458.15 KUM62352.1 - 0.27 9.8 0.5 6.3 5.3 0.0 3.3 5 0 0 5 5 5 0 Transferase family DIOX_N PF14226.6 KUM62353.1 - 1.2e-22 80.9 0.0 2e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KUM62353.1 - 1.3e-10 41.7 0.0 2.4e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily VLPT PF07122.11 KUM62353.1 - 0.081 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) Sugar_tr PF00083.24 KUM62354.1 - 8.4e-83 278.7 26.5 9.6e-83 278.5 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM62354.1 - 6.6e-30 104.2 27.1 6.6e-30 104.2 27.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily F420_oxidored PF03807.17 KUM62355.1 - 6.3e-06 26.7 0.0 1.5e-05 25.5 0.0 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Serine_rich PF08824.10 KUM62355.1 - 0.038 14.0 0.2 0.22 11.5 0.1 2.0 2 0 0 2 2 2 0 Serine rich protein interaction domain ApbA PF02558.16 KUM62355.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GMC_oxred_N PF00732.19 KUM62356.1 - 6.9e-45 153.7 0.4 1.2e-44 152.9 0.4 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM62356.1 - 1.2e-28 100.4 0.0 2.1e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KUM62356.1 - 4.1e-06 26.1 1.9 0.011 14.9 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KUM62356.1 - 7.5e-06 26.1 0.3 1.9e-05 24.8 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM62356.1 - 2.7e-05 23.9 6.8 0.00013 21.7 6.8 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KUM62356.1 - 0.00047 19.3 0.2 0.00072 18.7 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KUM62356.1 - 0.0037 16.5 0.2 0.053 12.8 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM62356.1 - 0.0049 16.1 0.7 0.013 14.7 0.1 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KUM62356.1 - 0.016 13.9 0.1 0.026 13.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 KUM62356.1 - 0.15 11.7 0.4 0.3 10.7 0.4 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 KUM62356.1 - 0.36 10.8 1.6 1.4 8.9 0.2 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding SH3_1 PF00018.28 KUM62357.1 - 0.063 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 SH3 domain TauD PF02668.16 KUM62358.1 - 6.6e-12 45.8 0.1 7.9e-12 45.5 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KUM62358.1 - 0.0062 15.7 0.0 0.0083 15.3 0.0 1.1 1 0 0 1 1 1 1 CsiD TilS PF09179.11 KUM62358.1 - 0.0068 16.9 0.4 1.1 9.8 0.2 2.2 2 0 0 2 2 2 2 TilS substrate binding domain Transferase PF02458.15 KUM62359.1 - 1.8e-16 59.8 0.0 3.6e-11 42.4 0.0 2.1 2 0 0 2 2 2 2 Transferase family stn_TNFRSF12A PF12191.8 KUM62360.1 - 0.036 14.3 0.6 0.053 13.8 0.3 1.4 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain EMP24_GP25L PF01105.24 KUM62361.1 - 6.4e-50 169.6 0.6 6.4e-50 169.6 0.6 1.3 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD ketoacyl-synt PF00109.26 KUM62362.1 - 2.8e-74 249.9 0.0 9.9e-74 248.1 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KUM62362.1 - 1.8e-60 205.2 0.3 2.7e-60 204.5 0.3 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KUM62362.1 - 1.2e-48 165.4 0.0 2.9e-48 164.2 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KUM62362.1 - 1.1e-47 162.7 0.0 1.8e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KUM62362.1 - 5.3e-39 132.9 0.0 2.9e-38 130.5 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KUM62362.1 - 3.3e-20 72.7 0.0 1.2e-19 70.9 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 KUM62362.1 - 3.3e-17 62.6 1.1 1.9e-16 60.1 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 KUM62362.1 - 8.8e-16 58.4 0.0 2.3e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KUM62362.1 - 8.6e-14 52.0 0.0 3e-12 47.1 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.26 KUM62362.1 - 8.1e-13 48.5 1.0 3.4e-12 46.5 0.1 2.7 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM62362.1 - 3.2e-11 44.4 0.0 1.7e-09 38.9 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KUM62362.1 - 4.8e-11 42.8 0.0 1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM62362.1 - 5.8e-10 39.7 0.0 2e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KUM62362.1 - 6.1e-08 32.5 0.0 1.8e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 KUM62362.1 - 3.5e-07 30.1 0.0 8e-06 25.7 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM62362.1 - 1.1e-06 28.2 0.0 2.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 KUM62362.1 - 1.3e-06 28.7 0.1 1.3e-06 28.7 0.1 2.5 2 0 0 2 2 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KUM62362.1 - 2.6e-06 27.0 0.4 7.4e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ADH_N PF08240.12 KUM62362.1 - 8.1e-06 25.7 0.1 1.8e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SAT PF16073.5 KUM62362.1 - 0.0032 17.2 1.5 0.013 15.3 1.5 1.9 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_24 PF13578.6 KUM62362.1 - 0.048 14.7 0.0 0.2 12.7 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_10 PF13460.6 KUM62362.1 - 0.14 12.0 1.2 1.3 8.9 0.2 2.4 2 0 0 2 2 2 0 NAD(P)H-binding ACP_syn_III PF08545.10 KUM62362.1 - 0.21 11.5 1.3 2.4 8.1 1.3 2.5 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FSH1 PF03959.13 KUM62363.1 - 4.1e-29 101.8 0.0 7.5e-29 100.9 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KUM62363.1 - 0.12 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Filament PF00038.21 KUM62364.1 - 0.00076 19.2 5.2 0.00076 19.2 5.2 4.9 3 1 2 5 5 5 2 Intermediate filament protein PAM2 PF07145.15 KUM62364.1 - 0.024 14.3 16.8 0.33 10.7 0.0 4.6 4 0 0 4 4 4 0 Ataxin-2 C-terminal region Glyco_hydro_17 PF00332.18 KUM62365.1 - 5.7e-40 137.8 0.1 2.8e-39 135.6 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 FAD_binding_4 PF01565.23 KUM62366.1 - 2.9e-14 53.0 1.3 5.2e-14 52.2 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KUM62366.1 - 0.0051 16.9 0.2 0.014 15.5 0.2 1.8 1 0 0 1 1 1 1 Berberine and berberine like ADH_zinc_N PF00107.26 KUM62367.1 - 1.7e-14 53.9 0.1 3.8e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM62367.1 - 4.8e-07 30.9 0.0 8.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM62367.1 - 1.5e-05 24.8 0.3 0.00014 21.7 0.3 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain FA_desaturase PF00487.24 KUM62369.1 - 6.1e-27 95.1 28.2 9.4e-27 94.4 28.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KUM62369.1 - 6.8e-11 42.2 0.0 1.4e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DASH_Dad3 PF08656.10 KUM62370.1 - 9.5e-27 92.9 0.5 1.6e-26 92.2 0.5 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad3 Pkinase PF00069.25 KUM62372.1 - 1.6e-74 250.6 0.0 2.2e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM62372.1 - 2.7e-30 105.5 0.0 1.5e-21 76.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KUM62372.1 - 1.2e-08 34.7 0.0 0.028 13.7 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KUM62372.1 - 0.0018 17.1 0.0 0.0036 16.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KUM62372.1 - 0.019 14.9 0.0 1.1 9.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KUM62372.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KUM62372.1 - 0.12 11.3 0.0 0.25 10.3 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Actin PF00022.19 KUM62373.1 - 1.1e-88 297.6 0.0 2.9e-54 184.2 0.0 2.2 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KUM62373.1 - 0.057 12.2 0.0 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Ribosomal_S5_C PF03719.15 KUM62375.1 - 4.1e-21 74.2 0.0 8.5e-21 73.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KUM62375.1 - 3.4e-15 55.8 0.0 3.4e-15 55.8 0.0 2.2 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Tautomerase PF01361.21 KUM62375.1 - 0.071 13.0 0.1 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Tautomerase enzyme tRNA_U5-meth_tr PF05958.11 KUM62376.1 - 1.4e-12 47.3 0.0 8.5e-11 41.4 0.0 2.5 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 KUM62376.1 - 8.5e-05 22.5 1.0 0.0002 21.3 0.3 2.0 2 0 0 2 2 2 1 TRAM domain Methyltransf_25 PF13649.6 KUM62376.1 - 0.0025 18.5 0.0 0.008 16.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM62376.1 - 0.0035 17.2 0.0 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 KUM62376.1 - 0.036 13.7 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KUM62376.1 - 0.053 12.9 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Asparaginase_2 PF01112.18 KUM62377.1 - 3.3e-49 167.6 2.4 3.2e-29 101.9 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.14 KUM62378.1 - 1e-119 399.1 0.0 1.2e-119 398.9 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 SIMPL PF04402.14 KUM62379.1 - 5e-26 92.4 0.0 6.5e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Gly_rich PF12810.7 KUM62379.1 - 0.00017 21.6 0.2 0.00027 20.9 0.2 1.3 1 0 0 1 1 1 1 Glycine rich protein DUF4426 PF14467.6 KUM62379.1 - 0.0034 17.4 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4426) LptE PF04390.12 KUM62379.1 - 0.035 14.8 0.2 0.072 13.8 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide-assembly Dodecin PF07311.12 KUM62379.1 - 0.12 12.7 0.9 0.41 10.9 0.2 2.2 2 0 0 2 2 2 0 Dodecin AA_permease_2 PF13520.6 KUM62380.1 - 8.4e-48 163.2 56.0 1.1e-47 162.9 56.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM62380.1 - 1.2e-25 90.1 48.6 1.6e-25 89.7 48.6 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 KUM62381.1 - 2e-48 165.3 0.0 5e-43 147.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 HRI1 PF16815.5 KUM62382.1 - 1.8e-24 86.7 0.0 5.7e-24 85.1 0.0 1.7 1 1 0 1 1 1 1 Protein HRI1 Glyco_hydro_3_C PF01915.22 KUM62383.1 - 9e-55 185.8 0.0 1.9e-54 184.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KUM62383.1 - 3.2e-47 161.5 0.0 5.7e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KUM62383.1 - 4.8e-23 81.0 0.0 1.2e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KUM62383.1 - 4.1e-12 46.1 0.0 7.3e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 PA14 domain TauD PF02668.16 KUM62384.1 - 5.1e-46 157.6 0.3 6.2e-46 157.3 0.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KUM62385.1 - 6.5e-18 64.8 15.7 8.2e-18 64.4 15.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5381 PF17353.2 KUM62385.1 - 9.8 5.9 9.8 33 4.2 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5381) zf-C2H2 PF00096.26 KUM62387.1 - 8e-06 26.0 10.5 0.0085 16.5 1.3 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM62387.1 - 0.022 15.6 7.8 0.29 12.1 0.6 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger CXCL17 PF15211.6 KUM62387.1 - 0.34 11.7 8.9 0.4 11.5 8.0 1.6 1 1 0 1 1 1 0 VEGF co-regulated chemokine 1 CHORD PF04968.12 KUM62387.1 - 0.54 11.0 3.8 5 7.9 0.2 2.3 1 1 1 2 2 2 0 CHORD FOXP-CC PF16159.5 KUM62387.1 - 2.6 8.7 6.1 16 6.2 0.3 2.9 1 1 1 2 2 2 0 FOXP coiled-coil domain ADH_zinc_N PF00107.26 KUM62388.1 - 1.7e-27 95.9 0.0 2.8e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM62388.1 - 2e-21 77.5 0.0 3.2e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM62388.1 - 9.4e-10 38.4 0.0 1.1e-08 34.9 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KUM62388.1 - 0.025 14.4 0.0 0.069 13.0 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase IPK PF03770.16 KUM62389.1 - 1.2e-59 201.5 0.0 1.8e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.10 KUM62390.1 - 4.7e-118 394.8 0.0 4.7e-118 394.8 0.0 1.6 2 0 0 2 2 2 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 CR6_interact PF10147.9 KUM62390.1 - 2.6 7.7 19.8 3.3 7.4 0.2 2.8 3 0 0 3 3 3 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 TFIID_30kDa PF03540.13 KUM62391.1 - 4.3e-22 77.8 0.1 6.4e-22 77.2 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 KUM62391.1 - 0.16 12.6 2.1 0.21 12.1 0.8 2.0 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_S19 PF00203.21 KUM62392.1 - 1.2e-24 86.0 0.0 1.5e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 His_Phos_2 PF00328.22 KUM62393.1 - 4.7e-06 26.2 0.0 3.7e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TRF PF08558.10 KUM62394.1 - 1.1e-87 293.6 0.8 1.6e-87 293.1 0.8 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KUM62394.1 - 0.00066 19.8 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Arginase PF00491.21 KUM62395.1 - 1.3e-90 303.7 0.0 1.5e-90 303.5 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KUM62395.1 - 0.18 12.1 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Methyltransf_22 PF13383.6 KUM62395.1 - 0.21 11.1 0.0 0.28 10.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans_2 PF11951.8 KUM62396.1 - 1.3e-50 172.4 4.6 1.8e-50 171.9 4.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM62396.1 - 3.9e-08 33.3 9.6 7.8e-08 32.3 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polysacc_deac_1 PF01522.21 KUM62397.1 - 2.5e-17 62.9 0.0 4.6e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KUM62397.1 - 6.1e-06 26.0 0.1 1.7e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KUM62397.1 - 0.011 14.1 0.0 0.016 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) HxlR PF01638.17 KUM62399.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Transmemb_17 PF09799.9 KUM62399.1 - 2.3 8.8 8.3 3.8 8.1 0.2 2.8 2 1 1 3 3 3 0 Predicted membrane protein F-box-like PF12937.7 KUM62400.1 - 1.2e-05 25.1 1.7 3.3e-05 23.7 1.7 1.8 1 0 0 1 1 1 1 F-box-like APH PF01636.23 KUM62401.1 - 2.9e-06 27.4 0.0 3.4e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4476 PF14771.6 KUM62401.1 - 0.1 12.9 0.4 0.15 12.4 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) GDPD PF03009.17 KUM62403.1 - 7.6e-71 238.9 0.0 1.5e-70 237.9 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KUM62403.1 - 3.1e-27 95.0 0.0 7.1e-09 36.1 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM62403.1 - 1.7e-24 85.8 2.8 6.5e-08 33.0 0.0 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.19 KUM62403.1 - 7.9e-24 85.3 12.8 4e-11 43.5 0.1 4.3 4 1 1 5 5 5 3 SPX domain Ank_3 PF13606.6 KUM62403.1 - 3.9e-18 63.7 0.2 0.014 15.8 0.0 7.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KUM62403.1 - 1.6e-16 60.1 0.1 9.7e-06 25.8 0.0 4.8 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KUM62403.1 - 3.8e-14 52.4 1.5 0.097 13.2 0.0 5.8 5 1 0 5 5 5 4 Ankyrin repeat CHAD PF05235.14 KUM62403.1 - 0.68 9.9 3.7 0.22 11.5 0.8 1.6 2 0 0 2 2 2 0 CHAD domain UNC45-central PF11701.8 KUM62404.1 - 6.7e-44 149.5 0.5 3.1e-43 147.4 0.5 2.3 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central Arm PF00514.23 KUM62404.1 - 0.038 14.1 20.6 2.5 8.3 0.6 7.6 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat TPR_15 PF13429.6 KUM62404.1 - 0.069 12.4 0.2 0.13 11.5 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_hydro_28 PF00295.17 KUM62405.1 - 2.4e-122 408.1 19.6 2.7e-122 407.9 19.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DP-EP PF08985.11 KUM62405.1 - 0.052 13.7 0.9 0.32 11.2 0.1 2.2 2 0 0 2 2 2 0 DP-EP family MFS_1 PF07690.16 KUM62406.1 - 1.8e-30 106.1 26.2 2.4e-30 105.7 26.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM62406.1 - 1.4e-08 34.1 4.9 1.4e-08 34.1 4.9 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KUM62406.1 - 0.002 16.6 2.0 0.002 16.6 2.0 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) COPIIcoated_ERV PF07970.12 KUM62407.1 - 9.5e-83 277.4 0.0 1.5e-82 276.8 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KUM62407.1 - 2.8e-29 101.3 0.0 5.3e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TAP_C PF03943.13 KUM62408.1 - 1.6e-16 59.7 0.9 2.9e-16 58.8 0.9 1.5 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.20 KUM62408.1 - 9.9e-08 32.6 0.0 1.8e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.7 KUM62408.1 - 0.00021 21.6 0.4 0.1 13.0 0.1 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KUM62408.1 - 0.00081 18.9 0.1 0.0014 18.1 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat RRM_9 PF18444.1 KUM62408.1 - 0.016 15.0 0.0 0.041 13.7 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif LRR_8 PF13855.6 KUM62408.1 - 0.048 13.4 0.2 0.22 11.3 0.2 2.2 1 1 0 1 1 1 0 Leucine rich repeat Vps53_N PF04100.12 KUM62409.1 - 2.6e-108 362.4 3.2 2.6e-108 362.4 3.2 1.7 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 KUM62409.1 - 9.2e-06 25.1 6.8 1.8e-05 24.2 6.8 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KUM62409.1 - 1.9e-05 24.6 0.2 7.6e-05 22.6 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) RINT1_TIP1 PF04437.13 KUM62409.1 - 0.00019 20.5 0.8 0.00019 20.5 0.8 2.9 2 1 0 2 2 2 1 RINT-1 / TIP-1 family COG2 PF06148.11 KUM62409.1 - 0.0069 16.5 6.1 0.0074 16.4 3.4 2.5 3 0 0 3 3 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Sigma70_ner PF04546.13 KUM62409.1 - 0.021 14.7 4.9 0.051 13.5 4.9 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region Zw10 PF06248.13 KUM62409.1 - 0.04 12.5 5.5 0.078 11.5 5.5 1.4 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Spc7 PF08317.11 KUM62409.1 - 0.049 12.5 5.8 0.096 11.6 5.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Sec8_exocyst PF04048.14 KUM62409.1 - 0.066 13.1 1.8 0.3 11.0 1.8 2.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain APG6_N PF17675.1 KUM62409.1 - 0.091 13.3 7.9 0.19 12.3 7.1 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Baculo_PEP_C PF04513.12 KUM62409.1 - 0.94 9.5 7.6 2 8.4 6.1 2.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5339 PF17274.2 KUM62409.1 - 1.2 10.1 5.4 19 6.2 0.3 3.1 1 1 1 2 2 2 0 Family of unknown function (DUF5339) XhlA PF10779.9 KUM62409.1 - 4.9 7.4 6.1 2.4 8.4 3.0 2.1 2 0 0 2 2 1 0 Haemolysin XhlA CorA PF01544.18 KUM62409.1 - 8 5.7 8.1 43 3.3 4.5 3.1 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein BLOC1_2 PF10046.9 KUM62409.1 - 8.2 6.8 8.7 2.9 8.3 3.2 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MFS_1 PF07690.16 KUM62410.1 - 9.7e-12 44.5 28.8 9.7e-12 44.5 28.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KUM62410.1 - 0.0053 15.1 1.1 0.0053 15.1 1.1 2.0 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family TMCCDC2 PF15844.5 KUM62411.1 - 0.13 12.2 0.8 0.35 10.8 0.8 1.7 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 GPI2 PF06432.11 KUM62411.1 - 6.8 6.0 13.8 0.24 10.8 1.4 2.4 3 0 0 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase Abhydrolase_6 PF12697.7 KUM62412.1 - 1.9e-13 51.5 0.2 3.7e-13 50.6 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM62412.1 - 0.0041 16.8 0.9 0.013 15.1 0.4 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM62412.1 - 0.061 12.6 0.5 2.5 7.3 0.0 2.6 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Ank_2 PF12796.7 KUM62415.1 - 1.5e-06 28.6 0.0 0.00082 19.9 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KUM62415.1 - 6.3e-05 23.1 0.0 3.8 8.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KUM62415.1 - 0.0014 19.2 0.0 1.8 9.3 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KUM62415.1 - 0.0072 16.7 0.0 1.4 9.5 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KUM62416.1 - 1.5e-134 438.9 29.7 7.3e-13 48.9 0.0 14.5 5 2 8 14 14 14 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM62416.1 - 8.1e-94 306.9 30.9 2.9e-09 37.3 0.0 21.6 11 5 13 25 25 25 18 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM62416.1 - 1.6e-85 270.7 29.8 7.7e-05 22.8 0.0 30.0 31 0 0 31 31 31 21 Ankyrin repeat Ank_5 PF13857.6 KUM62416.1 - 2.5e-82 269.8 41.8 2.2e-09 37.4 0.2 22.1 12 7 11 23 23 23 18 Ankyrin repeats (many copies) Ank PF00023.30 KUM62416.1 - 2.6e-74 242.7 56.0 2.7e-05 24.4 0.0 28.8 27 3 1 28 28 28 17 Ankyrin repeat SPRY PF00622.28 KUM62416.1 - 2e-16 60.2 0.2 5.1e-16 58.9 0.2 1.7 1 0 0 1 1 1 1 SPRY domain Gas_vesicle PF00741.18 KUM62416.1 - 0.75 10.0 3.8 18 5.6 1.0 3.0 2 0 0 2 2 2 0 Gas vesicle protein DnaJ_C PF01556.18 KUM62418.1 - 1e-38 132.7 0.3 1.4e-38 132.3 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KUM62418.1 - 2e-25 88.7 1.5 3.3e-25 88.0 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KUM62418.1 - 3.4e-15 56.2 19.4 5.7e-15 55.4 19.4 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KUM62418.1 - 1.1 9.3 9.7 0.53 10.3 2.5 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA dCMP_cyt_deam_1 PF00383.23 KUM62419.1 - 4.6e-22 77.8 0.0 5.9e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KUM62419.1 - 1.2e-19 70.4 0.0 1.4e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KUM62419.1 - 8.2e-06 25.9 2.0 0.068 13.2 0.6 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase SNAD4 PF18750.1 KUM62419.1 - 0.00052 20.1 0.0 0.0023 18.0 0.0 1.8 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD2 PF18782.1 KUM62419.1 - 0.0026 17.9 0.0 0.018 15.1 0.0 1.9 1 1 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC2 PF18772.1 KUM62419.1 - 0.0043 17.1 0.1 0.04 14.0 0.1 2.0 1 1 0 1 1 1 1 APOBEC2 APOBEC_N PF08210.11 KUM62419.1 - 0.0064 16.4 0.1 0.012 15.5 0.1 1.5 1 1 0 1 1 1 1 APOBEC-like N-terminal domain NAD1 PF18778.1 KUM62419.1 - 0.0067 16.5 0.1 0.035 14.2 0.1 1.9 1 1 0 1 1 1 1 Novel AID APOBEC clade 1 XOO_2897-deam PF14440.6 KUM62419.1 - 0.092 12.9 0.0 0.16 12.1 0.0 1.5 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase URO-D PF01208.17 KUM62420.1 - 3.8e-128 427.5 0.0 4.2e-128 427.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) WD40 PF00400.32 KUM62421.1 - 0.0017 19.1 0.3 0.027 15.3 0.0 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF2201_N PF13203.6 KUM62421.1 - 0.24 11.0 1.8 0.39 10.3 1.8 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Ribosomal_L10 PF00466.20 KUM62422.1 - 3.2e-23 81.7 0.0 6.8e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 KUM62422.1 - 2.9e-21 75.3 0.1 6.7e-21 74.1 0.0 1.7 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KUM62422.1 - 6.1e-20 71.6 1.2 6.1e-20 71.6 1.2 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Holin_SPP1 PF04688.13 KUM62422.1 - 0.086 13.0 0.2 0.4 10.9 0.1 2.0 1 1 1 2 2 2 0 SPP1 phage holin Sulfate_transp PF00916.20 KUM62423.1 - 1.8e-111 372.6 19.8 2.7e-111 372.0 19.8 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KUM62423.1 - 3.6e-08 33.0 0.0 6.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KUM62423.1 - 0.00059 20.2 2.8 0.00059 20.2 2.8 3.6 2 2 1 3 3 3 1 Molybdate transporter of MFS superfamily SNN_transmemb PF09049.10 KUM62423.1 - 2.1 8.3 9.8 0.068 13.1 2.0 2.7 2 0 0 2 2 2 0 Stannin transmembrane Peptidase_S8 PF00082.22 KUM62424.1 - 9.7e-18 64.4 0.2 3.3e-17 62.7 0.2 1.7 1 1 0 1 1 1 1 Subtilase family ZnuA PF01297.17 KUM62424.1 - 0.025 14.0 0.0 2.7 7.3 0.0 2.5 3 0 0 3 3 3 0 Zinc-uptake complex component A periplasmic PilO PF04350.13 KUM62424.1 - 0.098 12.8 0.1 2.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Pilus assembly protein, PilO PH PF00169.29 KUM62425.1 - 6.8e-09 36.2 0.0 2.6e-07 31.1 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KUM62425.1 - 0.097 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain MFS_1 PF07690.16 KUM62426.1 - 5.1e-05 22.3 2.3 5.4e-05 22.3 2.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily RNA_pol_Rpb6 PF01192.22 KUM62427.1 - 5.4e-17 61.4 0.1 9.6e-17 60.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 KOW PF00467.29 KUM62427.1 - 0.035 14.1 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 KOW motif zf-C2H2 PF00096.26 KUM62430.1 - 3.8e-31 105.8 53.3 5.9e-05 23.3 0.1 10.9 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM62430.1 - 3.2e-21 74.2 45.9 0.0057 17.4 0.1 10.7 10 0 0 10 10 10 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KUM62430.1 - 1.1e-15 57.2 56.6 7.1e-05 23.1 0.2 11.1 11 0 0 11 11 11 7 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KUM62430.1 - 1.7e-08 34.5 9.5 0.3 11.4 0.0 8.3 9 0 0 9 9 9 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KUM62430.1 - 1.7e-05 25.1 24.5 0.015 15.6 0.3 5.4 2 2 2 5 5 5 3 C2H2-type zinc ribbon FOXP-CC PF16159.5 KUM62430.1 - 4.8e-05 23.9 34.0 0.81 10.4 0.1 8.6 7 1 2 9 9 9 2 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KUM62430.1 - 0.011 15.4 12.6 20 5.0 0.1 6.2 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-met PF12874.7 KUM62430.1 - 0.84 10.1 11.6 1.2 9.6 0.0 5.8 8 0 0 8 8 8 0 Zinc-finger of C2H2 type GAGA PF09237.11 KUM62430.1 - 1.2 9.0 12.3 0.044 13.6 1.3 3.6 4 0 0 4 4 4 0 GAGA factor zf-C2H2_aberr PF17017.5 KUM62430.1 - 2.5 8.2 0.0 0.54 10.4 3.3 5.1 4 2 1 6 6 6 0 Aberrant zinc-finger MFS_1 PF07690.16 KUM62433.1 - 4e-20 72.0 52.2 2.2e-14 53.2 33.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 7tm_1 PF00001.21 KUM62433.1 - 0.0016 17.8 1.2 0.051 12.9 0.0 2.9 3 0 0 3 3 3 1 7 transmembrane receptor (rhodopsin family) DUF4808 PF16066.5 KUM62433.1 - 0.052 14.1 0.1 0.096 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) Acetyltransf_1 PF00583.25 KUM62434.1 - 2.1e-08 34.4 0.0 3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KUM62434.1 - 1.8e-06 27.9 0.0 3.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KUM62434.1 - 3.3e-06 27.0 0.0 5.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KUM62434.1 - 4.4e-05 23.8 0.0 6.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KUM62434.1 - 0.019 15.0 0.2 0.039 14.0 0.1 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KUM62435.1 - 1.3e-15 57.2 28.7 1.7e-15 56.8 28.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily HNH_2 PF13391.6 KUM62436.1 - 4.3e-09 36.4 0.1 9.3e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease Phage_ASH PF10554.9 KUM62436.1 - 0.17 12.2 0.1 0.32 11.3 0.1 1.4 1 0 0 1 1 1 0 Ash protein family Pantoate_transf PF02548.15 KUM62437.1 - 5.8e-105 350.3 1.2 6.8e-105 350.1 1.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KUM62437.1 - 3.3e-07 30.0 1.3 1.8e-06 27.6 1.3 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Mg_chelatase_C PF13335.6 KUM62437.1 - 0.028 15.0 0.0 0.06 14.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal ComA PF02679.15 KUM62437.1 - 0.081 12.4 0.0 0.3 10.5 0.0 1.9 1 1 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) NanE PF04131.14 KUM62437.1 - 0.21 10.7 1.7 7.2 5.8 0.1 2.7 2 1 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Ribosomal_S7 PF00177.21 KUM62439.1 - 1.3e-26 93.0 0.0 2.5e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Nucleo_P87 PF07267.11 KUM62440.1 - 1.1 8.1 13.4 1.2 8.0 13.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC27 PF09507.10 KUM62440.1 - 3.9 6.8 25.6 5.4 6.3 25.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SPX PF03105.19 KUM62441.1 - 2.8e-38 132.9 0.1 1.4e-25 91.1 0.0 2.1 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 KUM62441.1 - 4.7e-31 108.4 39.6 6.8e-31 107.8 39.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KUM62441.1 - 4.2e-24 85.3 72.3 2.9e-22 79.2 42.8 2.5 2 1 1 3 3 3 2 Citrate transporter DUF2470 PF10615.9 KUM62442.1 - 9.9e-18 64.6 0.1 1.5e-17 64.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) PBP1_TM PF14812.6 KUM62443.1 - 0.062 13.7 19.5 0.056 13.8 7.2 2.2 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1314 PF07013.11 KUM62444.1 - 0.037 13.9 0.0 0.046 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) Ribosomal_S8e PF01201.22 KUM62445.1 - 8e-54 181.5 0.8 9.2e-54 181.3 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Glyco_hydro81C PF17652.1 KUM62446.1 - 2.6e-169 563.0 8.0 3.3e-169 562.7 8.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KUM62446.1 - 3.1e-115 384.8 1.6 3.3e-115 384.7 0.4 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain TPPII_N PF12583.8 KUM62446.1 - 1.7 9.3 8.5 5.5 7.6 8.5 1.9 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Metallophos PF00149.28 KUM62447.1 - 2.3e-08 34.8 0.0 7.3e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KUM62447.1 - 3.9e-05 23.9 0.0 0.032 14.4 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain HECT PF00632.25 KUM62448.1 - 3.7e-72 243.4 0.0 4.8e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DAO PF01266.24 KUM62449.1 - 2.9e-61 208.0 1.2 4.1e-61 207.5 1.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase MAPEG PF01124.18 KUM62449.1 - 8.3e-17 61.3 2.0 1.6e-16 60.4 2.0 1.4 1 0 0 1 1 1 1 MAPEG family NAD_binding_8 PF13450.6 KUM62449.1 - 1.2e-05 25.5 0.2 3.6e-05 23.9 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM62449.1 - 0.00042 19.7 0.0 0.14 11.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KUM62449.1 - 0.001 18.4 0.3 0.045 13.0 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KUM62449.1 - 0.0044 16.3 0.0 0.015 14.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KUM62449.1 - 0.011 16.3 0.1 0.46 11.1 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KUM62449.1 - 0.02 14.3 1.9 0.15 11.4 1.9 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KUM62449.1 - 0.14 10.8 0.1 0.93 8.1 0.1 2.1 2 1 1 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 KUM62449.1 - 0.18 11.0 0.1 0.29 10.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM62449.1 - 0.39 9.7 2.3 1.2 8.1 2.3 1.8 1 1 0 1 1 1 0 FAD binding domain Rhabdo_glycop PF00974.18 KUM62450.1 - 0.048 12.1 0.0 0.057 11.9 0.0 1.0 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Pex24p PF06398.11 KUM62451.1 - 0.042 12.8 0.1 0.076 12.0 0.1 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin zf-RING_2 PF13639.6 KUM62453.1 - 3.1e-09 37.0 9.3 5.5e-09 36.2 9.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KUM62453.1 - 2.2e-08 33.7 1.4 6.6e-08 32.2 1.4 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KUM62453.1 - 1.9e-05 24.6 2.2 2.4e-05 24.3 0.7 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KUM62453.1 - 9.9e-05 22.1 9.3 0.00018 21.3 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM62453.1 - 0.0014 18.5 8.2 0.0026 17.6 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Orf78 PF06024.12 KUM62453.1 - 0.0032 17.8 0.0 0.0074 16.6 0.0 1.6 1 0 0 1 1 1 1 Orf78 (ac78) zf-RING_5 PF14634.6 KUM62453.1 - 0.0087 16.0 7.6 0.016 15.1 7.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain AA_permease_2 PF13520.6 KUM62453.1 - 0.043 12.7 0.0 0.056 12.3 0.0 1.1 1 0 0 1 1 1 0 Amino acid permease Stevor PF17410.2 KUM62453.1 - 0.19 11.2 0.2 0.33 10.5 0.2 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame zf-rbx1 PF12678.7 KUM62453.1 - 0.26 11.6 9.2 1 9.7 9.2 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 KUM62453.1 - 0.98 9.3 5.0 2 8.3 5.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KUM62453.1 - 1.2 9.1 11.5 2.7 7.9 11.1 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Ribosomal_L15e PF00827.17 KUM62454.1 - 9e-88 293.0 12.5 1.2e-87 292.7 12.5 1.1 1 0 0 1 1 1 1 Ribosomal L15 Fungal_trans PF04082.18 KUM62455.1 - 5.3e-13 48.6 0.2 1.8e-12 46.9 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain RAI16-like PF10257.9 KUM62455.1 - 0.12 11.2 0.0 0.28 10.0 0.0 1.5 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein WD40 PF00400.32 KUM62457.1 - 3.1e-52 173.4 17.0 4.6e-12 46.2 0.1 8.6 8 1 0 8 8 8 7 WD domain, G-beta repeat Pkinase PF00069.25 KUM62457.1 - 1.3e-48 165.7 0.0 2e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ANAPC4_WD40 PF12894.7 KUM62457.1 - 2.6e-29 101.3 0.1 1.6e-06 28.3 0.0 7.8 2 1 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Pkinase_Tyr PF07714.17 KUM62457.1 - 2.9e-24 85.8 0.0 4.1e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ge1_WD40 PF16529.5 KUM62457.1 - 8.4e-13 48.0 0.7 0.031 13.3 0.0 6.0 2 2 4 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KUM62457.1 - 1.2e-09 37.9 0.9 19 5.3 0.0 7.9 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KUM62457.1 - 4.9e-09 35.7 0.9 5.6 6.7 0.0 6.9 7 0 0 7 7 7 1 Proteasome subunit A N-terminal signature eIF2A PF08662.11 KUM62457.1 - 6.9e-08 32.6 0.1 0.0059 16.5 0.0 3.6 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KUM62457.1 - 7.1e-05 21.5 0.0 0.014 13.9 0.0 2.5 2 0 0 2 2 2 2 Cytochrome D1 heme domain DUF5122 PF17164.4 KUM62457.1 - 0.00026 21.2 0.2 21 5.5 0.0 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller Nup160 PF11715.8 KUM62457.1 - 0.0014 17.4 9.3 2.2 6.8 0.1 5.0 1 1 2 5 5 5 1 Nucleoporin Nup120/160 Kdo PF06293.14 KUM62457.1 - 0.0016 17.9 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WD40_like PF17005.5 KUM62457.1 - 0.0042 16.4 0.0 5.4 6.3 0.0 3.1 3 0 0 3 3 3 1 WD40-like domain DUF5570 PF17731.1 KUM62457.1 - 0.0045 17.1 2.5 24 5.1 0.0 5.3 3 1 2 6 6 6 0 Family of unknown function (DUF5570) Nbas_N PF15492.6 KUM62457.1 - 0.006 15.9 0.5 13 5.0 0.0 4.2 2 2 4 6 6 6 0 Neuroblastoma-amplified sequence, N terminal DUF5046 PF16465.5 KUM62457.1 - 0.0071 15.8 0.1 4.5 6.6 0.0 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF5046) PQQ_2 PF13360.6 KUM62457.1 - 0.015 14.9 4.6 1.2 8.7 3.7 3.5 1 1 2 3 3 3 0 PQQ-like domain PALB2_WD40 PF16756.5 KUM62457.1 - 0.026 13.4 1.2 9.4 5.0 0.0 3.7 2 2 3 5 5 5 0 Partner and localizer of BRCA2 WD40 domain TruB_C PF09142.11 KUM62457.1 - 0.073 12.9 0.0 62 3.5 0.0 4.1 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal TFIIIC_delta PF12657.7 KUM62457.1 - 0.095 12.6 3.8 19 5.1 0.0 4.3 4 0 0 4 4 4 0 Transcription factor IIIC subunit delta N-term Iso_dh PF00180.20 KUM62458.1 - 7.1e-88 295.1 0.0 8.5e-88 294.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Fungal_trans PF04082.18 KUM62459.1 - 9.9e-20 70.7 0.0 1.9e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_8 PF13450.6 KUM62460.1 - 3.7e-10 39.9 0.0 8.2e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM62460.1 - 0.026 14.1 0.0 0.62 9.6 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase HECT PF00632.25 KUM62461.1 - 6.9e-82 275.4 0.1 2.2e-81 273.7 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF983 PF06170.12 KUM62462.1 - 1.6 9.2 8.2 2.8 8.4 8.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Utp14 PF04615.13 KUM62463.1 - 2.3e-206 687.8 84.7 2.3e-206 687.8 84.7 2.4 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.9 KUM62464.1 - 0.019 14.8 0.3 0.052 13.4 0.3 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 Ribosomal_L14e PF01929.17 KUM62464.1 - 0.034 14.7 0.0 0.057 13.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L14 RRM_1 PF00076.22 KUM62465.1 - 3.3e-77 254.3 6.5 5.7e-19 67.7 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KUM62465.1 - 8.4e-29 99.6 0.4 5.3e-28 97.0 0.6 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KUM62465.1 - 4.8e-11 42.3 0.6 0.011 15.3 0.0 5.0 3 2 2 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KUM62465.1 - 1.5e-05 24.9 1.9 1.4 9.0 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KUM62465.1 - 2.3e-05 24.4 0.8 6.7 6.9 0.0 5.5 5 1 0 5 5 5 1 RNA recognition motif YflT PF11181.8 KUM62465.1 - 0.00046 20.6 1.7 0.15 12.6 1.2 2.8 2 0 0 2 2 2 1 Heat induced stress protein YflT CbiG_mid PF11761.8 KUM62465.1 - 0.0021 18.1 0.0 23 5.2 0.0 3.6 3 0 0 3 3 3 0 Cobalamin biosynthesis central region CSD PF00313.22 KUM62465.1 - 0.15 12.0 2.8 37 4.3 0.0 3.5 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain SOBP PF15279.6 KUM62465.1 - 0.23 12.0 13.3 0.26 11.9 12.1 1.6 1 1 0 1 1 1 0 Sine oculis-binding protein Limkain-b1 PF11608.8 KUM62465.1 - 0.24 11.5 3.4 4.3 7.5 0.2 3.4 3 0 0 3 3 3 0 Limkain b1 OB_RNB PF08206.11 KUM62465.1 - 0.37 10.5 3.6 14 5.5 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain Presenilin PF01080.17 KUM62465.1 - 9.5 4.9 10.3 15 4.2 10.3 1.3 1 0 0 1 1 1 0 Presenilin Fungal_trans PF04082.18 KUM62466.1 - 3.7e-24 85.2 3.5 4.2e-24 85.0 0.8 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain CENP-H PF05837.12 KUM62466.1 - 0.12 12.8 0.0 0.39 11.1 0.0 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF1656 PF07869.12 KUM62469.1 - 0.17 11.9 0.9 0.3 11.1 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Ada3 PF10198.9 KUM62470.1 - 1.3e-46 158.0 0.1 1.3e-46 158.0 0.1 2.1 2 1 0 2 2 2 1 Histone acetyltransferases subunit 3 NPR2 PF06218.11 KUM62471.1 - 1.8e-134 448.9 0.0 1.4e-133 445.9 0.0 2.0 1 1 0 1 1 1 1 Nitrogen permease regulator 2 Amidohydro_1 PF01979.20 KUM62472.1 - 3.7e-76 256.7 2.4 6.3e-76 255.9 1.2 1.8 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.20 KUM62472.1 - 5.7e-57 191.3 0.5 1.4e-56 190.0 0.5 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 KUM62472.1 - 7.1e-38 128.9 0.1 1.8e-37 127.6 0.1 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 KUM62472.1 - 8.8e-37 125.1 0.1 2.3e-28 98.1 0.0 3.0 2 1 1 3 3 3 2 Urease beta subunit Amidohydro_3 PF07969.11 KUM62472.1 - 6.9e-09 35.7 0.6 5.6e-05 22.8 0.1 2.6 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 KUM62472.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Amidohydrolase HMG_box PF00505.19 KUM62473.1 - 7.7e-11 42.3 1.5 1.5e-10 41.3 1.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KUM62473.1 - 8.1e-06 26.3 3.0 2.3e-05 24.9 2.1 2.2 2 0 0 2 2 2 1 HMG-box domain FAM220 PF15487.6 KUM62473.1 - 0.62 9.7 5.1 0.86 9.2 5.1 1.2 1 0 0 1 1 1 0 FAM220 family Trypan_PARP PF05887.11 KUM62473.1 - 3.3 7.7 22.4 2 8.4 20.5 1.6 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DRMBL PF07522.14 KUM62474.1 - 7.9e-06 26.0 0.2 3e-05 24.2 0.1 2.1 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase ABC2_membrane PF01061.24 KUM62476.1 - 3.3e-17 62.6 12.0 3.6e-17 62.5 12.0 1.0 1 0 0 1 1 1 1 ABC-2 type transporter P5-ATPase PF12409.8 KUM62476.1 - 0.0014 18.8 0.6 0.0014 18.8 0.6 1.7 2 0 0 2 2 2 1 P5-type ATPase cation transporter Utp12 PF04003.12 KUM62476.1 - 0.042 14.2 0.1 0.069 13.5 0.1 1.4 1 1 0 1 1 1 0 Dip2/Utp12 Family ABC2_membrane_3 PF12698.7 KUM62476.1 - 0.35 9.9 11.7 0.38 9.8 11.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Zn_clus PF00172.18 KUM62477.1 - 2.4e-09 37.2 9.7 3.6e-09 36.6 9.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM62478.1 - 7.1e-07 28.5 0.0 1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM62478.1 - 1.7e-06 28.0 9.7 3.3e-06 27.1 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 KUM62479.1 - 2.1e-60 204.5 0.0 6.5e-60 202.9 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM62479.1 - 0.0041 18.1 0.0 0.01 16.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TPR_2 PF07719.17 KUM62480.1 - 3.5e-08 33.0 7.3 0.0031 17.5 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KUM62480.1 - 1.6e-05 24.5 3.8 0.048 13.5 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KUM62480.1 - 0.00074 19.1 5.9 1.9 8.3 0.0 5.5 6 1 0 6 6 6 1 TPR repeat TPR_16 PF13432.6 KUM62480.1 - 0.021 15.4 4.1 1.9 9.2 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KUM62480.1 - 0.049 14.3 0.7 11 6.9 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KUM62480.1 - 0.085 13.2 3.2 3.1 8.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KUM62480.1 - 0.11 13.4 6.8 13 6.9 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF1897 PF09005.10 KUM62480.1 - 0.14 11.7 0.4 0.32 10.5 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) TPR_19 PF14559.6 KUM62480.1 - 0.19 12.3 7.6 4.8 7.8 0.1 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KUM62480.1 - 0.57 10.7 2.0 2.1e+02 2.7 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KUM62481.1 - 3.8e-23 81.9 0.9 3.8e-23 81.9 0.9 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain NACHT PF05729.12 KUM62482.1 - 4.1e-10 39.8 0.1 9.7e-10 38.6 0.1 1.7 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 KUM62482.1 - 1e-07 31.5 0.0 2.8e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.6 KUM62482.1 - 1.9e-07 31.4 0.0 4.8e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KUM62482.1 - 1e-05 26.0 0.0 3.3e-05 24.4 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.6 KUM62482.1 - 0.0021 18.6 0.0 0.0052 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KUM62482.1 - 0.0033 17.9 0.0 0.0066 17.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter KAP_NTPase PF07693.14 KUM62482.1 - 0.009 15.3 0.4 1.2 8.3 0.0 2.2 1 1 0 2 2 2 1 KAP family P-loop domain AAA_29 PF13555.6 KUM62482.1 - 0.048 13.4 0.2 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KUM62482.1 - 0.049 13.5 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Ploopntkinase3 PF18751.1 KUM62482.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 KUM62482.1 - 0.077 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 KUM62482.1 - 0.078 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 KUM62482.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain GP52 PF17468.2 KUM62482.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Phage gene product 52 NB-ARC PF00931.22 KUM62482.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sm_multidrug_ex PF06695.11 KUM62482.1 - 0.13 12.9 0.0 0.34 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative small multi-drug export protein RICTOR_M PF14666.6 KUM62482.1 - 0.16 11.8 0.1 19 5.1 0.0 3.2 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain RNA_pol_Rpc34 PF05158.12 KUM62483.1 - 5.2e-113 377.8 0.0 5.9e-113 377.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_46 PF15977.5 KUM62483.1 - 0.016 15.2 0.1 0.12 12.4 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding MarR PF01047.22 KUM62483.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 MarR family PadR PF03551.14 KUM62483.1 - 0.18 11.7 0.1 0.85 9.6 0.1 2.1 1 1 1 2 2 2 0 Transcriptional regulator PadR-like family TPR_1 PF00515.28 KUM62484.1 - 2.3e-44 147.5 22.4 6.8e-06 25.7 0.1 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 KUM62484.1 - 7.3e-37 125.1 13.2 3.3e-20 71.8 0.2 2.8 2 0 0 2 2 2 2 STI1 domain TPR_2 PF07719.17 KUM62484.1 - 2.1e-34 114.8 22.1 4.9e-05 23.1 0.1 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 KUM62484.1 - 1.7e-19 69.2 22.6 0.00056 19.5 0.4 8.3 5 3 3 8 8 8 5 TPR repeat TPR_12 PF13424.6 KUM62484.1 - 1.4e-18 66.9 18.2 6.7e-07 29.5 2.2 6.5 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KUM62484.1 - 1.3e-17 64.2 8.8 8.5e-05 23.1 0.1 6.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KUM62484.1 - 1.3e-16 59.3 23.9 6.4e-05 22.9 0.2 8.0 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KUM62484.1 - 3.5e-12 46.1 11.5 0.36 11.8 0.0 8.6 5 3 3 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 KUM62484.1 - 6.5e-12 45.8 14.7 0.0051 17.3 0.1 6.8 6 2 1 7 7 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 KUM62484.1 - 1.1e-09 37.6 8.3 0.049 13.7 0.0 7.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KUM62484.1 - 1.2e-09 37.9 5.4 0.44 11.0 0.2 7.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 KUM62484.1 - 2.2e-09 37.3 9.2 0.01 16.0 0.4 5.1 2 2 3 5 5 5 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KUM62484.1 - 2e-08 34.2 0.8 0.05 13.7 0.0 4.7 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KUM62484.1 - 1.2e-05 25.0 13.5 0.0011 18.8 0.3 6.7 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 KUM62484.1 - 8.6e-05 22.9 17.1 4.8 8.0 0.0 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_20 PF14561.6 KUM62484.1 - 0.00033 20.9 0.3 0.00033 20.9 0.3 5.1 4 2 1 5 5 5 1 Tetratricopeptide repeat MIT PF04212.18 KUM62484.1 - 0.063 13.4 13.7 9.9 6.3 0.8 5.8 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 KUM62484.1 - 0.065 13.2 11.7 2.2 8.3 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 KUM62484.1 - 0.11 12.2 12.3 8.2 6.1 0.0 5.4 3 3 3 6 6 6 0 26S proteasome subunit RPN7 PPR PF01535.20 KUM62484.1 - 0.2 12.0 2.0 28 5.3 0.1 4.0 5 0 0 5 5 3 0 PPR repeat DUF5113 PF17140.4 KUM62484.1 - 1.4 8.7 10.0 7.6 6.3 0.1 4.3 4 2 2 6 6 5 0 Domain of unknown function (DUF5113) Alkyl_sulf_dimr PF14863.6 KUM62484.1 - 4.4 7.8 10.8 18 5.7 0.1 4.6 3 3 0 3 3 3 0 Alkyl sulfatase dimerisation BTAD PF03704.17 KUM62484.1 - 6.4 7.2 9.1 76 3.7 0.1 4.5 2 2 1 5 5 5 0 Bacterial transcriptional activator domain LCE6A PF15858.5 KUM62485.1 - 0.057 14.2 0.8 0.091 13.5 0.8 1.3 1 0 0 1 1 1 0 Late cornified envelope protein 6A family Intg_mem_TP0381 PF09529.10 KUM62487.1 - 0.021 14.3 3.4 0.027 14.0 3.4 1.1 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) ING PF12998.7 KUM62488.1 - 2.2e-24 85.9 3.7 3.8e-24 85.2 3.7 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KUM62488.1 - 3.3e-05 23.7 9.6 5.9e-05 22.9 9.6 1.4 1 0 0 1 1 1 1 PHD-finger TFIIA PF03153.13 KUM62488.1 - 0.013 15.5 13.2 0.012 15.7 12.0 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-HC5HC2H PF13771.6 KUM62488.1 - 0.026 14.8 0.1 0.076 13.3 0.1 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KUM62488.1 - 0.44 10.1 4.7 0.92 9.1 4.7 1.6 1 0 0 1 1 1 0 PHD-finger AMPK1_CBM PF16561.5 KUM62491.1 - 6.5e-05 23.1 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase FSH1 PF03959.13 KUM62492.1 - 5.5e-20 72.0 0.0 6.3e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Methyltransf_23 PF13489.6 KUM62493.1 - 0.0048 16.7 0.0 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain ketoacyl-synt PF00109.26 KUM62494.1 - 8.3e-70 235.2 0.0 1.4e-69 234.5 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KUM62494.1 - 3.3e-53 180.9 0.0 5.5e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KUM62494.1 - 2.9e-51 173.9 0.0 7.8e-51 172.5 0.0 1.7 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KUM62494.1 - 4.7e-38 129.8 0.3 1.3e-37 128.4 0.0 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KUM62494.1 - 7.3e-35 121.0 0.0 1.1e-34 120.4 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.12 KUM62494.1 - 3.6e-19 69.3 0.0 1.9e-18 67.0 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM62494.1 - 5e-15 55.7 0.0 1.6e-14 54.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KUM62494.1 - 2.2e-14 53.9 0.0 5.7e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KUM62494.1 - 3.2e-11 43.0 0.0 6.5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KUM62494.1 - 8.1e-11 42.5 0.0 3.8e-10 40.3 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KUM62494.1 - 5.1e-10 39.4 0.0 1.3e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 KUM62494.1 - 5.2e-10 39.3 0.0 1.2e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM62494.1 - 6e-10 39.7 0.0 2.1e-09 37.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KUM62494.1 - 9.4e-09 35.2 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N_2 PF13602.6 KUM62494.1 - 8.3e-07 30.1 0.0 8e-05 23.7 0.0 3.4 4 0 0 4 4 3 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.18 KUM62494.1 - 2.7e-05 23.6 0.0 8.1e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.15 KUM62494.1 - 0.00027 20.2 0.0 0.00043 19.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Thiolase_N PF00108.23 KUM62494.1 - 0.00045 19.7 0.1 0.00094 18.6 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.19 KUM62494.1 - 0.0029 16.7 0.0 0.0049 15.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KUM62494.1 - 0.0034 17.0 0.0 0.0073 15.9 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KUM62494.1 - 0.0092 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ACP_syn_III PF08545.10 KUM62494.1 - 0.029 14.2 1.5 0.044 13.6 0.2 2.0 2 0 0 2 2 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Epimerase PF01370.21 KUM62494.1 - 0.03 13.8 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_16 PF10294.9 KUM62494.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Sacchrp_dh_NADP PF03435.18 KUM62494.1 - 0.11 12.8 0.1 0.7 10.2 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KUM62494.1 - 0.19 12.3 0.1 5.6 7.6 0.1 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Thiolase_N PF00108.23 KUM62495.1 - 2.3e-51 174.7 0.7 3.1e-51 174.3 0.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KUM62495.1 - 6.1e-14 51.7 2.5 8.9e-14 51.2 0.3 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KUM62495.1 - 0.0013 18.4 0.5 0.0034 17.0 0.3 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain RNA_pol_Rpb2_6 PF00562.28 KUM62496.1 - 5.1e-123 411.0 0.1 7.3e-123 410.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KUM62496.1 - 3e-60 203.2 0.0 5.5e-60 202.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KUM62496.1 - 1.1e-45 155.6 0.0 1.9e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KUM62496.1 - 2.9e-33 114.1 0.0 6.5e-33 113.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KUM62496.1 - 3.3e-25 88.1 0.3 7.7e-25 86.9 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KUM62496.1 - 4.3e-24 84.6 1.0 1.3e-23 83.1 1.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KUM62496.1 - 1.2e-21 77.0 0.1 3.6e-21 75.5 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 KUM62496.1 - 0.21 12.3 0.0 0.45 11.2 0.0 1.5 1 0 0 1 1 1 0 MRN-interacting protein CTNNBL PF08216.11 KUM62497.1 - 9.6e-41 138.2 0.8 7.6e-40 135.3 0.2 2.6 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Mo25 PF08569.11 KUM62497.1 - 0.003 17.0 0.2 0.0053 16.2 0.2 1.5 1 0 0 1 1 1 1 Mo25-like DUF913 PF06025.12 KUM62497.1 - 0.023 13.7 0.2 1.9 7.4 0.1 2.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF913) Dynactin_p22 PF07426.11 KUM62497.1 - 0.073 12.9 1.8 0.17 11.8 1.8 1.7 1 0 0 1 1 1 0 Dynactin subunit p22 Arm PF00514.23 KUM62497.1 - 0.079 13.0 0.0 24 5.2 0.0 3.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Drf_GBD PF06371.13 KUM62497.1 - 0.12 11.9 0.1 0.49 9.9 0.0 2.1 1 1 1 2 2 2 0 Diaphanous GTPase-binding Domain DUF1471 PF07338.13 KUM62499.1 - 0.019 15.0 0.1 0.05 13.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) C2 PF00168.30 KUM62500.1 - 1.3e-76 253.4 0.2 1.4e-20 73.5 0.0 5.7 6 0 0 6 6 6 5 C2 domain SMP_LBD PF17047.5 KUM62500.1 - 5.1e-05 22.8 0.0 0.0001 21.8 0.0 1.5 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain NT-C2 PF10358.9 KUM62500.1 - 0.0028 17.4 0.0 3.9 7.2 0.0 2.8 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins UDPGP PF01704.18 KUM62501.1 - 7.8e-191 634.1 0.1 9e-191 633.9 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.13 KUM62501.1 - 0.0079 16.4 0.1 0.025 14.7 0.0 1.8 2 0 0 2 2 2 1 Pilus assembly protein, PilO AT_hook PF02178.19 KUM62502.1 - 5.3e-06 25.7 24.9 0.033 14.0 2.9 4.1 3 0 0 3 3 3 3 AT hook motif AP_endonuc_2 PF01261.24 KUM62503.1 - 1.3e-24 86.8 0.0 2e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MFS_1 PF07690.16 KUM62504.1 - 3.5e-11 42.6 8.2 1.1e-10 41.0 8.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM62504.1 - 0.012 14.5 1.4 0.14 11.0 0.4 2.1 2 1 0 2 2 2 0 Sugar (and other) transporter His_Phos_1 PF00300.22 KUM62506.1 - 2.3e-15 56.8 0.1 1.5e-13 50.9 0.0 2.8 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) Glyco_hydro_3_C PF01915.22 KUM62507.1 - 1.7e-47 162.1 0.0 4.3e-47 160.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KUM62507.1 - 3e-42 145.1 0.0 4.6e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KUM62507.1 - 6.8e-20 70.9 0.1 1.2e-19 70.2 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.16 KUM62508.1 - 8.8e-45 153.2 80.5 9.3e-43 146.5 57.5 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM62508.1 - 1.7e-14 53.6 15.9 1.7e-14 53.6 15.9 3.1 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KUM62508.1 - 1.4e-12 46.8 31.1 2.2e-12 46.2 30.8 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KUM62508.1 - 6.1 5.0 27.2 0.13 10.5 6.9 3.8 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family DUF21 PF01595.20 KUM62509.1 - 5.1e-31 107.7 0.0 8.2e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KUM62509.1 - 0.002 18.5 3.5 0.037 14.5 0.0 3.5 4 0 0 4 4 4 1 CBS domain AhpC-TSA PF00578.21 KUM62511.1 - 1.6e-30 105.6 0.0 2.1e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KUM62511.1 - 1e-13 51.2 0.0 1.3e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KUM62511.1 - 9.8e-13 47.7 0.2 1.5e-12 47.1 0.2 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Methyltransf_23 PF13489.6 KUM62512.1 - 5.2e-08 32.9 0.0 7.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM62512.1 - 6.3e-07 30.0 0.0 1.9e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM62512.1 - 5.3e-06 27.1 0.0 2.2e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM62512.1 - 0.00032 21.3 0.0 0.003 18.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM62512.1 - 0.00083 19.2 0.0 0.002 17.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 KUM62512.1 - 0.14 11.6 0.0 0.46 10.0 0.0 1.8 2 1 0 2 2 2 0 AdoMet dependent proline di-methyltransferase TPR_MLP1_2 PF07926.12 KUM62513.1 - 0.0053 16.8 60.1 0.24 11.5 0.2 5.3 4 1 1 5 5 5 2 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 KUM62513.1 - 0.0062 16.6 2.0 0.0062 16.6 2.0 4.0 3 1 1 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.6 KUM62513.1 - 0.023 14.7 4.1 0.023 14.7 4.1 4.7 2 1 2 4 4 3 0 FlxA-like protein DUF812 PF05667.11 KUM62513.1 - 0.03 13.2 29.3 0.014 14.3 20.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) BLOC1_2 PF10046.9 KUM62513.1 - 0.031 14.6 4.4 0.031 14.6 4.4 5.0 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AT_hook PF02178.19 KUM62513.1 - 0.089 12.7 0.3 0.22 11.5 0.3 1.7 1 0 0 1 1 1 0 AT hook motif DASH_Dam1 PF08653.10 KUM62513.1 - 0.47 10.3 6.5 2.5 8.0 2.9 3.2 2 1 1 3 3 3 0 DASH complex subunit Dam1 Phi-29_GP16_7 PF06720.11 KUM62513.1 - 0.58 10.0 6.5 0.3 10.9 2.2 2.4 2 0 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 UPF0242 PF06785.11 KUM62513.1 - 0.7 10.0 41.2 1.1 9.3 0.1 4.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 KUM62513.1 - 1 9.8 15.6 4.2 7.8 4.5 5.3 4 1 2 6 6 6 0 Flagella accessory protein C (FlaC) AlaDh_PNT_C PF01262.21 KUM62513.1 - 2.5 7.4 4.8 4.1 6.6 0.0 2.9 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Lectin_N PF03954.14 KUM62513.1 - 6.3 6.6 12.9 5 6.9 0.8 4.0 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain Gly_transf_sug PF04488.15 KUM62514.1 - 6e-10 39.6 0.1 1.2e-09 38.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KUM62514.1 - 0.00089 18.7 0.1 0.0013 18.2 0.1 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TraS PF10624.9 KUM62514.1 - 0.088 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS MR_MLE_C PF13378.6 KUM62515.1 - 1e-19 71.0 0.0 2.4e-19 69.8 0.0 1.5 1 1 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KUM62515.1 - 2.6e-14 53.4 0.0 6.4e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fe-ADH PF00465.19 KUM62516.1 - 9.9e-104 347.0 0.0 1.2e-103 346.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KUM62516.1 - 2.3e-14 53.7 0.0 2.8e-11 43.6 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 KUM62516.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Arylsulfotran_2 PF14269.6 KUM62517.1 - 1.2e-112 376.1 8.4 1.6e-112 375.8 8.4 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) FAD_binding_7 PF03441.14 KUM62519.1 - 9.3e-54 182.0 0.4 1e-53 181.8 0.4 1.0 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase TRH PF05438.12 KUM62520.1 - 0.062 13.0 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) 2-Hacid_dh_C PF02826.19 KUM62521.1 - 4.1e-55 185.9 0.0 7e-55 185.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KUM62521.1 - 5.2e-36 123.3 0.2 9e-36 122.5 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 KUM62521.1 - 0.0017 18.9 0.0 0.0049 17.4 0.0 1.8 1 0 0 1 1 1 1 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 KUM62521.1 - 0.0096 15.2 0.9 0.03 13.6 0.9 1.8 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 KUM62521.1 - 0.02 15.0 0.0 0.043 13.9 0.0 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 KUM62521.1 - 0.046 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ACT PF01842.25 KUM62521.1 - 0.08 12.7 0.5 0.54 10.1 0.0 2.7 2 1 0 2 2 2 0 ACT domain Fungal_trans_2 PF11951.8 KUM62522.1 - 7.9e-08 31.5 0.4 1.6e-07 30.5 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM62522.1 - 3.3e-07 30.3 8.1 7.1e-07 29.3 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Haem_degrading PF03928.14 KUM62524.1 - 1.9e-35 121.5 0.4 2.4e-35 121.1 0.4 1.1 1 0 0 1 1 1 1 Haem-degrading HSP70 PF00012.20 KUM62525.1 - 1e-258 859.5 15.2 1.2e-258 859.3 15.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KUM62525.1 - 6.1e-17 61.4 1.1 1.4e-15 57.0 0.3 2.2 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 KUM62525.1 - 0.0019 17.3 0.1 0.013 14.5 0.1 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 KUM62525.1 - 0.088 12.1 3.0 0.62 9.3 0.2 3.0 3 1 0 3 3 3 0 Hydantoinase/oxoprolinase GLE1 PF07817.13 KUM62525.1 - 0.21 10.8 1.6 2.6 7.2 0.0 2.9 3 0 0 3 3 3 0 GLE1-like protein DUF4845 PF16137.5 KUM62525.1 - 0.29 12.0 2.9 3 8.8 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4845) FtsA PF14450.6 KUM62525.1 - 0.57 10.6 7.9 13 6.3 0.3 3.7 3 2 0 3 3 3 0 Cell division protein FtsA FIVAR PF07554.13 KUM62525.1 - 0.72 10.7 7.9 53 4.7 0.1 4.2 3 1 0 3 3 3 0 FIVAR domain GTP_EFTU PF00009.27 KUM62526.1 - 3.8e-49 166.9 0.0 5.9e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KUM62526.1 - 9e-18 64.4 3.9 1.6e-17 63.6 3.9 1.4 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.25 KUM62526.1 - 1.5e-09 38.1 0.0 3.6e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KUM62526.1 - 1.7e-08 34.7 0.0 1.3e-07 31.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KUM62526.1 - 8.9e-08 32.2 0.0 2.9e-06 27.4 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KUM62526.1 - 0.00037 20.0 0.1 0.048 13.1 0.1 2.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KUM62526.1 - 0.00094 18.6 0.1 0.0018 17.6 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KUM62526.1 - 0.0039 16.7 0.0 1.7 8.0 0.0 2.3 1 1 1 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KUM62526.1 - 0.0076 16.5 0.1 2.7 8.2 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KUM62526.1 - 0.019 14.6 0.1 0.44 10.1 0.0 2.2 2 0 0 2 2 2 0 Ras family FeoB_N PF02421.18 KUM62526.1 - 0.03 13.8 0.4 0.92 9.0 0.2 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B Acyltransf_C PF16076.5 KUM62526.1 - 0.044 13.9 0.0 0.098 12.8 0.0 1.6 1 0 0 1 1 1 0 Acyltransferase C-terminus Septin PF00735.18 KUM62526.1 - 0.062 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Septin Met_asp_mut_E PF06368.11 KUM62526.1 - 0.083 11.3 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Ribosomal_L23 PF00276.20 KUM62526.1 - 0.13 12.7 0.1 0.33 11.3 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L23 DUF3810 PF12725.7 KUM62526.1 - 0.13 11.5 0.3 0.22 10.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) PBP1_TM PF14812.6 KUM62526.1 - 1.6 9.1 4.0 4.9 7.6 4.0 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 KUM62527.1 - 0.031 13.9 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 FAM176 family DUF3404 PF11884.8 KUM62527.1 - 0.045 13.0 0.0 0.051 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) Exotox-A_bind PF09101.10 KUM62527.1 - 0.072 12.4 0.0 0.082 12.2 0.0 1.1 1 0 0 1 1 1 0 Exotoxin A binding zf-C2H2_2 PF12756.7 KUM62529.1 - 2.9e-37 127.1 20.1 5.4e-32 110.1 5.0 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KUM62529.1 - 2.7e-06 27.5 8.3 2.7e-06 27.5 8.3 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KUM62529.1 - 7.2e-06 26.2 11.1 2.7e-05 24.4 6.6 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KUM62529.1 - 0.017 15.5 24.2 0.045 14.2 2.8 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM62529.1 - 0.049 14.5 15.7 2 9.5 0.9 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger ASCH PF04266.14 KUM62529.1 - 0.12 12.9 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 ASCH domain zf-C2H2_6 PF13912.6 KUM62529.1 - 1.1 9.4 10.5 2.5 8.2 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger HECT PF00632.25 KUM62530.1 - 6.7e-72 242.6 0.0 1.1e-71 241.8 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KUM62530.1 - 2.2e-20 72.7 1.2 4.7e-20 71.6 1.2 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Aminotran_1_2 PF00155.21 KUM62531.1 - 3.5e-53 181.0 0.0 4.2e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HpcH_HpaI PF03328.14 KUM62532.1 - 1.5e-27 96.2 0.0 1.9e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 KUM62532.1 - 0.0005 19.1 0.0 0.00074 18.5 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain TauD PF02668.16 KUM62533.1 - 1.7e-57 195.2 2.8 2.3e-57 194.8 2.8 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cys_Met_Meta_PP PF01053.20 KUM62534.1 - 1.6e-27 96.1 0.0 3e-27 95.2 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KUM62534.1 - 6.6e-07 28.8 0.0 1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_M20 PF01546.28 KUM62535.1 - 6.5e-24 84.8 0.0 8.9e-22 77.8 0.0 2.4 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KUM62535.1 - 5.9e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KUM62535.1 - 6e-05 22.8 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 WD40 PF00400.32 KUM62535.1 - 0.0023 18.7 23.3 0.09 13.7 0.1 7.0 7 1 0 7 7 7 2 WD domain, G-beta repeat PQQ_3 PF13570.6 KUM62535.1 - 1.4 9.5 3.4 1.1e+02 3.4 0.0 4.4 4 0 0 4 4 4 0 PQQ-like domain TraQ PF09679.10 KUM62536.1 - 0.034 14.1 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) PT PF04886.12 KUM62536.1 - 0.1 12.2 15.2 0.085 12.4 3.7 3.5 4 1 0 4 4 4 0 PT repeat Bys1 PF04681.12 KUM62538.1 - 6.3e-09 35.9 0.0 8.7e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein HpcH_HpaI PF03328.14 KUM62539.1 - 3.8e-24 85.1 0.0 8.6e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Methyltransf_33 PF10017.9 KUM62539.1 - 1.1e-20 74.0 0.0 2.3e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Sipho_Gp157 PF05565.11 KUM62539.1 - 0.0073 16.3 16.6 0.096 12.7 7.9 2.5 2 0 0 2 2 2 2 Siphovirus Gp157 CortBP2 PF09727.9 KUM62539.1 - 0.0075 16.2 24.3 0.01 15.8 14.5 2.3 2 0 0 2 2 2 2 Cortactin-binding protein-2 Prefoldin_2 PF01920.20 KUM62539.1 - 0.07 13.1 11.8 0.77 9.7 0.1 2.8 3 0 0 3 3 3 0 Prefoldin subunit Cor1 PF04803.12 KUM62539.1 - 0.092 13.0 4.5 0.23 11.7 3.3 2.4 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region Methyltransf_12 PF08242.12 KUM62539.1 - 0.13 13.0 0.6 1.9 9.3 0.0 2.9 2 1 1 3 3 3 0 Methyltransferase domain bZIP_1 PF00170.21 KUM62539.1 - 0.27 11.4 14.5 0.25 11.5 2.4 3.6 2 1 1 3 3 3 0 bZIP transcription factor DUF4736 PF15883.5 KUM62539.1 - 0.38 10.4 3.2 0.95 9.2 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) TPR_MLP1_2 PF07926.12 KUM62539.1 - 0.82 9.7 34.0 2.3 8.3 6.6 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KUM62539.1 - 1.4 9.0 7.9 1.7 8.7 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KUM62539.1 - 6 7.3 6.6 15 6.1 0.7 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TauD PF02668.16 KUM62540.1 - 1.9e-27 96.7 8.6 3.5e-27 95.9 8.6 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ribosomal_S6e PF01092.19 KUM62541.1 - 1.2e-55 186.8 0.6 1.9e-55 186.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e HMG_box PF00505.19 KUM62542.1 - 2.5e-23 82.3 0.8 4.5e-23 81.5 0.8 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KUM62542.1 - 1.3e-09 38.5 0.4 2.7e-09 37.5 0.4 1.6 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KUM62542.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Ctf8 PF09696.10 KUM62543.1 - 1.9e-45 154.7 0.1 2e-44 151.4 0.1 2.0 1 1 0 1 1 1 1 Ctf8 Dabb PF07876.12 KUM62544.1 - 2.9e-12 47.0 0.0 3.5e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF1687 PF07955.11 KUM62544.1 - 0.025 15.1 0.0 0.029 14.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) Fungal_trans PF04082.18 KUM62546.1 - 2.6e-18 66.0 5.2 4.1e-18 65.4 5.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM62546.1 - 2e-06 27.8 14.1 4e-06 26.9 14.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5630 PF18632.1 KUM62546.1 - 0.06 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5630) RuvX PF03652.15 KUM62546.1 - 0.22 11.9 0.3 0.48 10.8 0.3 1.5 1 0 0 1 1 1 0 Holliday junction resolvase MRG PF05712.13 KUM62547.1 - 1.5e-52 177.8 0.0 1.7e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 MRG PPTA PF01239.22 KUM62548.1 - 3.2e-37 125.2 14.1 1e-07 31.5 0.0 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat MutS_III PF05192.18 KUM62548.1 - 1.2 9.3 3.7 5.1 7.3 3.7 1.9 1 1 0 1 1 1 0 MutS domain III TIP49 PF06068.13 KUM62549.1 - 3.9e-167 555.8 0.0 4.7e-167 555.6 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KUM62549.1 - 1.1e-19 70.3 0.0 3.3e-19 68.8 0.0 1.9 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 KUM62549.1 - 3.5e-11 43.7 0.1 3.8e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KUM62549.1 - 2e-10 40.7 0.1 6.6e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KUM62549.1 - 8.5e-06 26.1 0.1 0.043 14.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KUM62549.1 - 0.00012 22.5 0.1 0.0016 18.9 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KUM62549.1 - 0.00014 22.2 0.7 0.086 13.2 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KUM62549.1 - 0.00082 19.6 0.2 0.0019 18.4 0.1 1.7 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 KUM62549.1 - 0.00083 19.4 0.2 0.19 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KUM62549.1 - 0.0014 18.3 0.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 KUM62549.1 - 0.0061 15.9 0.3 0.015 14.6 0.3 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.6 KUM62549.1 - 0.0076 15.8 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KUM62549.1 - 0.016 14.6 0.1 0.76 9.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 KUM62549.1 - 0.043 13.1 0.1 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ATPase PF06745.13 KUM62549.1 - 0.049 13.0 0.7 0.15 11.4 0.1 1.9 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 KUM62549.1 - 0.057 13.2 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KUM62549.1 - 0.06 13.9 0.0 0.28 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KUM62549.1 - 0.071 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KUM62549.1 - 0.1 12.1 0.1 0.43 10.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 KUM62549.1 - 0.11 12.2 0.2 1.7 8.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain TetR_C_30 PF17939.1 KUM62549.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CN_hydrolase PF00795.22 KUM62550.1 - 1.5e-34 119.5 0.0 2.4e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase An_peroxidase PF03098.15 KUM62551.1 - 7.4e-39 133.7 0.0 6.3e-28 97.6 0.0 3.4 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KUM62551.1 - 8.1e-09 34.7 0.1 2.9e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF2407_C PF13373.6 KUM62553.1 - 6.3e-44 149.6 0.4 9.7e-44 148.9 0.4 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KUM62553.1 - 8e-36 122.8 0.1 2.6e-35 121.1 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KUM62553.1 - 0.00053 19.7 0.0 0.00097 18.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family V-SNARE PF05008.15 KUM62554.1 - 5e-20 71.6 4.2 5e-20 71.6 4.2 2.4 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KUM62554.1 - 1.8e-15 57.0 4.4 1.8e-15 57.0 4.4 2.8 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KUM62554.1 - 0.00053 19.8 0.3 0.00053 19.8 0.3 2.3 2 1 0 2 2 2 1 Sec20 Fusion_gly PF00523.18 KUM62554.1 - 0.001 17.4 2.1 0.0011 17.3 0.2 1.9 2 0 0 2 2 2 1 Fusion glycoprotein F0 Thump_like PF18096.1 KUM62554.1 - 0.0029 17.5 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 THUMP domain-like SNARE PF05739.19 KUM62554.1 - 0.0051 16.8 0.9 0.016 15.2 0.9 1.9 1 0 0 1 1 1 1 SNARE domain Laminin_II PF06009.12 KUM62554.1 - 0.023 14.7 0.4 0.023 14.7 0.4 2.7 1 1 1 3 3 3 0 Laminin Domain II CHDCT2 PF08074.11 KUM62554.1 - 0.096 12.9 2.9 0.71 10.0 0.1 2.2 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain BORCS8 PF10167.9 KUM62554.1 - 0.12 12.3 1.1 0.7 9.9 0.0 2.3 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 YqjK PF13997.6 KUM62554.1 - 0.64 10.3 7.7 1.1 9.6 0.0 3.2 3 0 0 3 3 3 0 YqjK-like protein Synaptobrevin PF00957.21 KUM62554.1 - 1.6 8.6 8.4 0.3 10.9 2.3 2.8 3 2 1 4 4 4 0 Synaptobrevin zf-C4H2 PF10146.9 KUM62554.1 - 2.2 8.5 8.7 0.53 10.6 1.1 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein Exonuc_VII_L PF02601.15 KUM62554.1 - 4.4 6.8 13.9 30 4.0 13.9 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit CCDC-167 PF15188.6 KUM62554.1 - 4.5 7.7 12.8 9.5 6.6 4.9 3.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 ZapA PF05164.13 KUM62554.1 - 4.6 7.8 13.6 11 6.5 0.1 3.0 2 1 0 2 2 2 0 Cell division protein ZapA DUF2408 PF10303.9 KUM62554.1 - 4.7 7.8 8.5 4 8.0 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Steroid_dh PF02544.16 KUM62555.1 - 3.4e-31 108.3 1.2 4.5e-31 107.9 1.2 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KUM62555.1 - 8.5e-07 28.7 1.7 1.3e-06 28.2 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KUM62555.1 - 0.0036 17.7 0.4 0.0036 17.7 0.4 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase Cnl2_NKP2 PF09447.10 KUM62556.1 - 3.6e-27 94.3 0.7 3.6e-27 94.3 0.7 2.1 2 0 0 2 2 2 1 Cnl2/NKP2 family protein DUF5082 PF16888.5 KUM62556.1 - 0.01 16.1 2.8 1.8 8.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Mod_r PF07200.13 KUM62556.1 - 0.028 14.5 0.7 0.042 14.0 0.7 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein KfrA_N PF11740.8 KUM62556.1 - 0.037 14.7 1.6 1.6 9.5 0.1 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Sld5 PF05916.11 KUM62556.1 - 0.061 13.8 0.1 12 6.4 0.3 2.1 1 1 1 2 2 2 0 GINS complex protein GlutR_dimer PF00745.20 KUM62556.1 - 0.092 13.2 2.1 0.11 12.9 0.5 1.9 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain APG6_N PF17675.1 KUM62556.1 - 0.13 12.8 3.5 7.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region ABC_tran_CTD PF16326.5 KUM62556.1 - 2.2 8.6 8.0 2.3 8.6 1.8 2.7 1 1 1 2 2 2 0 ABC transporter C-terminal domain Glyco_transf_34 PF05637.12 KUM62558.1 - 7e-63 212.5 0.0 9.5e-63 212.1 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 KUM62558.1 - 0.0081 15.7 0.0 0.14 11.7 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF273 zf-C2H2_12 PF18658.1 KUM62558.1 - 0.09 12.4 0.2 10 5.8 0.0 2.5 2 1 0 2 2 2 0 Zinc-finger C2H2-type Aa_trans PF01490.18 KUM62560.1 - 5e-48 163.8 32.1 5.7e-48 163.6 32.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Utp12 PF04003.12 KUM62562.1 - 2.8e-24 85.5 0.0 4.7e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KUM62562.1 - 0.043 14.1 0.0 38 4.7 0.0 4.2 3 1 2 5 5 4 0 Anaphase-promoting complex subunit 4 WD40 domain Costars PF14705.6 KUM62562.1 - 0.16 12.2 0.0 0.46 10.7 0.0 1.7 1 0 0 1 1 1 0 Costars HAUS4 PF14735.6 KUM62563.1 - 4.3e-06 26.6 3.1 6.9e-06 25.9 1.9 2.0 2 1 0 2 2 2 1 HAUS augmin-like complex subunit 4 DUF1843 PF08898.10 KUM62563.1 - 0.23 12.0 4.7 0.41 11.2 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Ku_C PF03730.14 KUM62563.1 - 0.76 10.5 4.3 0.36 11.5 0.3 2.6 3 0 0 3 3 3 0 Ku70/Ku80 C-terminal arm Bromodomain PF00439.25 KUM62564.1 - 3.5e-38 129.5 0.9 4.9e-20 71.4 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KUM62564.1 - 2.1e-20 72.7 1.4 4.7e-20 71.5 1.4 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF3573 PF12097.8 KUM62564.1 - 1.4 7.7 3.5 2.4 6.9 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Frataxin_Cyay PF01491.16 KUM62565.1 - 3.9e-35 120.2 0.0 5.8e-35 119.6 0.0 1.3 1 0 0 1 1 1 1 Frataxin-like domain DUF4167 PF13763.6 KUM62565.1 - 0.35 11.0 2.2 0.58 10.3 1.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4167) zf-CSL PF05207.13 KUM62566.1 - 1.5e-22 79.1 0.3 1.9e-22 78.7 0.3 1.1 1 0 0 1 1 1 1 CSL zinc finger DUF3987 PF13148.6 KUM62567.1 - 0.012 14.7 8.9 0.015 14.3 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) CCDC53 PF10152.9 KUM62567.1 - 3.5 8.0 6.4 1.6 9.1 0.2 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Glyco_hydro_cc PF11790.8 KUM62568.1 - 1.7e-67 227.5 0.9 1.9e-67 227.3 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core WD40 PF00400.32 KUM62569.1 - 4.6e-07 30.4 1.0 0.00043 21.0 0.0 4.0 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM62569.1 - 7.2e-07 29.4 0.1 0.012 15.9 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Pribosyltran_N PF13793.6 KUM62571.1 - 1.3e-45 154.1 0.5 1.1e-44 151.0 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KUM62571.1 - 6e-40 137.2 1.6 3.7e-33 115.1 0.7 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KUM62571.1 - 1.1e-17 64.0 1.0 1.5e-16 60.3 0.6 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KUM62571.1 - 0.00023 20.7 0.2 0.00041 19.9 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF913 PF06025.12 KUM62572.1 - 2.6e-130 434.7 0.0 2.6e-130 434.7 0.0 5.7 5 1 0 5 5 5 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KUM62572.1 - 2.4e-111 372.7 6.1 2.4e-111 372.7 6.1 2.8 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) HECT PF00632.25 KUM62572.1 - 5.4e-95 318.4 0.0 9e-95 317.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 KUM62572.1 - 4.3e-29 99.0 22.6 2e-10 39.8 2.1 4.3 3 0 0 3 3 3 3 Ubiquitin binding region Tudor-knot PF11717.8 KUM62573.1 - 2.6e-09 36.8 2.2 5.2e-09 35.9 2.2 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KUM62573.1 - 0.014 15.3 2.2 0.026 14.4 2.2 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Glyoxalase PF00903.25 KUM62574.1 - 3.5e-17 62.8 0.1 4.4e-14 52.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KUM62574.1 - 2e-11 44.1 0.0 2.8e-05 24.3 0.0 3.0 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KUM62574.1 - 6e-06 26.5 0.0 0.078 13.1 0.0 3.1 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KUM62574.1 - 0.00023 21.3 0.1 0.32 11.2 0.0 3.0 3 0 0 3 3 3 2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF1338 PF07063.13 KUM62574.1 - 0.065 12.4 0.1 0.28 10.3 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1338) RabGAP-TBC PF00566.18 KUM62575.1 - 3.6e-52 177.1 0.1 3e-51 174.1 0.0 2.6 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Z1 PF10593.9 KUM62575.1 - 0.83 9.1 7.1 1.8 8.0 7.1 1.6 1 0 0 1 1 1 0 Z1 domain Mago_nashi PF02792.14 KUM62575.1 - 1 9.5 3.0 0.68 10.0 0.2 2.0 1 1 1 2 2 2 0 Mago nashi protein Ribosomal_L12 PF00542.19 KUM62575.1 - 8.4 6.8 8.4 0.37 11.2 1.7 2.2 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain Fe-S_biosyn PF01521.20 KUM62576.1 - 6.9e-19 68.1 0.0 9.3e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF1741 PF08427.10 KUM62577.1 - 1.9e-91 305.9 0.0 3.3e-91 305.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) MBOAT_2 PF13813.6 KUM62577.1 - 0.11 12.8 0.1 0.32 11.3 0.1 1.8 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family PTR2 PF00854.21 KUM62578.1 - 1.7e-73 247.8 10.0 2.3e-73 247.3 10.0 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KUM62578.1 - 1.6e-10 40.5 21.8 1.5e-09 37.3 21.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF21 PF01595.20 KUM62578.1 - 9.5 5.9 11.6 3.2 7.4 0.5 3.4 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain Abhydrolase_1 PF00561.20 KUM62581.1 - 8.5e-49 166.5 0.0 2.7e-48 164.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KUM62581.1 - 0.00025 21.7 4.5 0.00093 19.9 4.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM62581.1 - 0.095 11.9 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 CBP_CCPA PF17040.5 KUM62581.1 - 0.23 12.0 2.7 2.9 8.5 0.0 2.9 3 1 0 3 3 3 0 Cellulose-complementing protein A PLA2_B PF01735.18 KUM62582.1 - 1e-207 690.4 2.0 1.2e-207 690.2 2.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF5583 PF17821.1 KUM62583.1 - 0.017 15.0 0.0 0.07 13.1 0.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5583) PTCB-BRCT PF12738.7 KUM62583.1 - 0.21 11.6 0.1 2.7 8.0 0.0 2.3 2 0 0 2 2 2 0 twin BRCT domain DAHP_synth_2 PF01474.16 KUM62584.1 - 1e-200 666.9 0.0 1.1e-200 666.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family FMN_bind_2 PF04299.12 KUM62586.1 - 1.3e-59 200.7 0.0 1.5e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Putative FMN-binding domain Sulfatase PF00884.23 KUM62587.1 - 4.5e-19 69.0 1.6 7.9e-19 68.2 1.6 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KUM62587.1 - 3.7e-07 30.0 0.1 6.6e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KUM62587.1 - 0.00082 18.1 0.1 0.0013 17.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) adh_short_C2 PF13561.6 KUM62588.1 - 7.4e-58 195.9 0.2 8.5e-58 195.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM62588.1 - 7.8e-47 159.3 1.5 9.9e-47 158.9 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM62588.1 - 3.1e-14 53.3 0.5 4.2e-14 52.9 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM62588.1 - 1.5e-05 24.6 0.1 2e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM62588.1 - 0.028 13.8 0.1 0.11 11.9 0.0 1.9 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase HNH_repeat PF18780.1 KUM62588.1 - 0.06 13.2 1.2 0.16 11.8 1.2 1.7 1 0 0 1 1 1 0 Homing endonuclease repeat Fungal_trans PF04082.18 KUM62589.1 - 2.3e-10 39.9 1.4 2.3e-10 39.9 1.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain COG2 PF06148.11 KUM62590.1 - 0.062 13.4 1.1 0.091 12.9 1.1 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Remorin_C PF03763.13 KUM62590.1 - 0.074 12.9 7.1 0.12 12.2 7.1 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region bZIP_2 PF07716.15 KUM62590.1 - 0.096 12.8 9.8 0.16 12.1 9.8 1.4 1 0 0 1 1 1 0 Basic region leucine zipper UPF0449 PF15136.6 KUM62590.1 - 7.7 7.1 11.5 0.094 13.2 2.7 2.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 Nucleo_P87 PF07267.11 KUM62590.1 - 8.5 5.1 6.6 12 4.6 6.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 adh_short PF00106.25 KUM62591.1 - 1.2e-33 116.2 0.0 2.4e-33 115.3 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM62591.1 - 1e-21 77.6 0.0 1.5e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM62591.1 - 7.6e-09 35.7 0.0 1e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KUM62591.1 - 0.00012 22.4 0.0 0.00067 19.9 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KUM62591.1 - 0.0043 17.0 0.1 0.0058 16.5 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KUM62591.1 - 0.0045 16.4 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KUM62591.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Aldedh PF00171.22 KUM62592.1 - 1.6e-184 613.7 0.2 1.8e-184 613.6 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KUM62592.1 - 0.0018 17.7 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) IPI_T4 PF11634.8 KUM62592.1 - 0.046 13.7 0.1 5.7 7.0 0.0 2.8 3 0 0 3 3 3 0 Nuclease inhibitor from bacteriophage T4 DUF5133 PF17196.4 KUM62592.1 - 0.99 9.6 3.6 6.2 7.1 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) SGL PF08450.12 KUM62593.1 - 2.5e-72 243.4 0.0 3.1e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region MitMem_reg PF13012.6 KUM62595.1 - 2.3e-11 44.1 6.5 6.3e-11 42.7 6.5 1.7 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KUM62595.1 - 1.6e-08 34.5 0.0 6.2e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Herpes_UL35 PF04496.12 KUM62595.1 - 0.056 13.8 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus UL35 family FAD_binding_1 PF00667.20 KUM62596.1 - 2.3e-30 105.8 0.0 3.6e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KUM62596.1 - 1e-29 103.6 0.0 1.5e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KUM62596.1 - 1.5e-15 57.8 0.0 1.7e-14 54.4 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KUM62596.1 - 0.004 17.4 0.0 0.035 14.3 0.0 2.4 2 1 1 3 3 3 1 Flavodoxin domain Flavodoxin_3 PF12641.7 KUM62596.1 - 0.007 16.1 0.0 0.021 14.5 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin domain RNA_pol_3_Rpc31 PF11705.8 KUM62597.1 - 8.4e-61 206.1 12.6 1.1e-60 205.8 12.6 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Glyco_hydro_67M PF07488.12 KUM62598.1 - 7.9e-146 485.3 0.1 1.2e-145 484.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 KUM62598.1 - 4.4e-90 301.1 4.6 6.5e-90 300.6 4.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 KUM62598.1 - 1.2e-33 115.9 0.0 2.4e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 KUM62598.1 - 0.0041 17.9 0.0 0.012 16.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Ribosomal_L7Ae PF01248.26 KUM62599.1 - 4e-25 87.4 0.0 4.5e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Solute_trans_a PF03619.16 KUM62600.1 - 9.4e-91 304.0 22.5 1.1e-90 303.8 22.5 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4781 PF16013.5 KUM62600.1 - 0.046 12.5 0.5 0.074 11.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) MAGI_u5 PF16666.5 KUM62600.1 - 5.2 7.2 9.4 9 6.5 9.4 1.3 1 0 0 1 1 1 0 Unstructured region on MAGI DUF1129 PF06570.11 KUM62600.1 - 6.1 6.3 11.2 0.98 8.9 3.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) SAP PF02037.27 KUM62601.1 - 7.3e-09 35.2 0.2 1.2e-08 34.5 0.2 1.4 1 0 0 1 1 1 1 SAP domain RSB_motif PF16294.5 KUM62601.1 - 7e-06 26.2 0.5 7e-06 26.2 0.5 4.4 2 2 1 4 4 4 1 RNSP1-SAP18 binding (RSB) motif AhpC-TSA PF00578.21 KUM62602.1 - 1.4e-30 105.8 0.0 2.3e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KUM62602.1 - 3.4e-15 56.0 0.0 4.5e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KUM62602.1 - 1e-13 50.9 0.1 1.8e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Phage_TTP_11 PF16460.5 KUM62602.1 - 0.098 12.5 0.2 16 5.4 0.0 2.3 2 0 0 2 2 2 0 Phage tail tube, TTP, lambda-like Peptidase_S8 PF00082.22 KUM62603.1 - 4.8e-09 35.9 0.0 1.2e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Subtilase family PGBA_C PF15437.6 KUM62603.1 - 0.0081 16.5 0.5 0.0081 16.5 0.5 1.8 2 0 0 2 2 2 1 Plasminogen-binding protein pgbA C-terminal ANAPC9 PF12856.7 KUM62603.1 - 0.072 13.3 0.4 0.17 12.1 0.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 EVE PF01878.18 KUM62604.1 - 2e-48 164.1 0.4 3.4e-48 163.4 0.4 1.4 1 0 0 1 1 1 1 EVE domain AT_hook PF02178.19 KUM62604.1 - 9.1e-06 25.0 45.7 0.03 14.2 2.0 5.2 5 0 0 5 5 5 4 AT hook motif RPA43_OB PF17875.1 KUM62604.1 - 1.5 9.5 6.4 7.2 7.3 5.6 2.2 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Kelch_4 PF13418.6 KUM62606.1 - 4.6e-18 64.9 0.0 1.3e-05 25.1 0.0 5.1 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KUM62606.1 - 1.5e-13 50.3 2.9 8.2e-05 22.5 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 KUM62606.1 - 1.6e-13 50.6 3.5 6e-09 36.0 0.0 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 KUM62606.1 - 6.4e-12 44.9 0.0 0.0034 16.9 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 KUM62606.1 - 4.5e-11 42.6 4.3 0.013 15.8 0.0 5.4 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KUM62606.1 - 4e-10 39.2 0.1 0.001 19.0 0.0 4.7 4 1 0 4 4 4 3 Kelch motif PNP_UDP_1 PF01048.20 KUM62607.1 - 0.00022 20.6 0.0 0.0011 18.3 0.0 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily FOXP-CC PF16159.5 KUM62607.1 - 0.17 12.6 0.9 5.3 7.8 0.1 2.8 2 0 0 2 2 2 0 FOXP coiled-coil domain Pkinase PF00069.25 KUM62608.1 - 1.2e-08 34.7 0.0 7.3e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM62608.1 - 0.0024 17.2 0.0 0.076 12.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KUM62608.1 - 0.0031 16.9 0.1 0.0074 15.7 0.1 1.6 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribophorin_II PF05817.14 KUM62609.1 - 6.3e-32 110.9 0.0 7.8e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II WD40 PF00400.32 KUM62611.1 - 0.00021 22.0 9.1 0.57 11.2 0.0 5.5 5 1 0 5 5 5 2 WD domain, G-beta repeat DUF4578 PF15147.6 KUM62611.1 - 1.8 9.4 3.7 1.5 9.7 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) ATP-synt_E PF05680.12 KUM62612.1 - 1.9e-26 92.3 0.7 2e-26 92.1 0.7 1.0 1 0 0 1 1 1 1 ATP synthase E chain Adhesin_P1_N PF18652.1 KUM62612.1 - 0.019 15.0 3.8 0.028 14.4 3.8 1.5 1 1 0 1 1 1 0 Adhesin P1 N-terminal domain FCH PF00611.23 KUM62612.1 - 0.022 15.0 1.7 0.022 15.0 1.7 1.4 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Chordopox_A13L PF05961.11 KUM62612.1 - 0.089 13.0 1.8 0.28 11.4 0.7 1.9 1 1 1 2 2 2 0 Chordopoxvirus A13L protein CHD5 PF04420.14 KUM62612.1 - 0.21 11.4 1.1 0.25 11.2 1.1 1.2 1 0 0 1 1 1 0 CHD5-like protein CSN8_PSD8_EIF3K PF10075.9 KUM62613.1 - 2.3e-31 108.7 0.0 3.3e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SDH_sah PF01972.16 KUM62613.1 - 0.14 11.1 0.0 0.61 9.0 0.0 1.8 2 0 0 2 2 2 0 Serine dehydrogenase proteinase DUF1275 PF06912.11 KUM62615.1 - 1.1e-31 110.2 6.5 1.4e-31 110.0 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) AzlC PF03591.14 KUM62615.1 - 0.087 13.3 8.6 0.059 13.8 3.8 2.2 2 1 0 2 2 2 0 AzlC protein Con-6 PF10346.9 KUM62616.1 - 2.1e-24 85.2 2.9 1.1e-14 54.1 1.1 2.2 2 0 0 2 2 2 2 Conidiation protein 6 ATP-synt_DE PF00401.20 KUM62616.1 - 1.3 9.3 8.2 0.28 11.5 1.1 2.9 3 1 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain FMO-like PF00743.19 KUM62617.1 - 8.2e-27 93.8 0.0 5.2e-09 35.1 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KUM62617.1 - 1.2e-12 47.7 0.1 8.8e-06 25.2 0.1 3.4 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM62617.1 - 1.2e-09 37.9 0.1 6e-08 32.3 0.1 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM62617.1 - 3.3e-08 33.7 0.0 0.00019 21.5 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KUM62617.1 - 6.9e-06 25.4 0.1 0.034 13.3 0.0 3.5 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KUM62617.1 - 8.3e-06 25.9 0.0 3.9e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM62617.1 - 0.001 18.8 0.4 4.3 6.8 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KUM62617.1 - 0.0029 16.9 0.1 0.034 13.4 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KUM62617.1 - 0.026 15.1 0.6 5.5 7.6 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PdxA PF04166.12 KUM62617.1 - 0.052 12.9 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA FAD_oxidored PF12831.7 KUM62617.1 - 0.056 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3453 PF11935.8 KUM62618.1 - 5.1e-71 238.9 0.4 1.9e-70 237.0 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Sds3 PF08598.11 KUM62619.1 - 2.6e-20 73.4 0.7 2.6e-20 73.4 0.7 2.0 2 0 0 2 2 2 1 Sds3-like SUIM_assoc PF16619.5 KUM62619.1 - 0.015 15.4 8.3 0.049 13.7 8.3 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 STT3 PF02516.14 KUM62620.1 - 6.5e-17 61.6 0.2 7.3e-17 61.5 0.2 1.0 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Pyr_redox_3 PF13738.6 KUM62621.1 - 1.9e-12 47.1 0.0 4e-12 46.0 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KUM62621.1 - 6.5e-11 41.4 0.0 1.2e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KUM62621.1 - 7.6e-10 38.5 0.0 1.7e-09 37.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM62621.1 - 2.5e-07 30.2 0.0 7.8e-06 25.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KUM62621.1 - 9e-07 29.0 0.1 2.6e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KUM62621.1 - 8e-05 22.0 0.4 0.00019 20.8 0.1 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KUM62621.1 - 0.0014 18.6 0.2 0.028 14.4 0.2 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KUM62621.1 - 0.011 14.5 0.2 0.57 8.8 0.1 2.3 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 KUM62621.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KUM62621.1 - 0.11 11.5 0.1 0.24 10.4 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KUM62621.1 - 0.12 11.6 0.0 0.74 9.1 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.24 KUM62621.1 - 0.14 11.7 0.2 2 7.9 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase STT3 PF02516.14 KUM62622.1 - 4.3e-113 378.8 31.1 4.8e-108 362.2 29.3 2.2 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit NAD_binding_1 PF00175.21 KUM62623.1 - 6.6e-32 110.4 0.0 1.1e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KUM62623.1 - 3.1e-27 94.8 0.0 6.6e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KUM62623.1 - 5.9e-22 77.6 0.3 5.9e-22 77.6 0.3 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KUM62623.1 - 1e-05 25.7 0.0 0.00028 21.1 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KUM62623.1 - 0.18 12.0 0.0 9.1 6.5 0.0 2.4 1 1 0 2 2 2 0 Siderophore-interacting FAD-binding domain p450 PF00067.22 KUM62624.1 - 2.8e-69 234.1 0.0 3.3e-69 233.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KUM62626.1 - 1.9e-24 86.1 1.2 2.7e-24 85.6 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF5541 PF17695.1 KUM62626.1 - 0.12 12.8 0.1 0.26 11.7 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5541) 3HCDH_N PF02737.18 KUM62627.1 - 7.6e-32 110.6 0.0 1.1e-31 110.2 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KUM62627.1 - 2.5e-08 34.4 0.0 4.9e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 KUM62627.1 - 2.7e-05 24.2 0.0 4.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 KUM62627.1 - 0.00081 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ldl_recept_b PF00058.17 KUM62627.1 - 0.013 15.9 1.5 9.4 6.8 0.2 4.4 4 1 0 4 4 4 0 Low-density lipoprotein receptor repeat class B 2-Hacid_dh_C PF02826.19 KUM62627.1 - 0.087 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N PF08240.12 KUM62629.1 - 7.7e-20 70.8 1.3 1.4e-19 70.0 1.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM62629.1 - 2.3e-17 63.2 0.0 4e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KUM62629.1 - 1.9e-05 24.0 0.2 3.3e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KUM62629.1 - 8.2e-05 22.0 0.3 0.00014 21.3 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KUM62629.1 - 0.019 14.9 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KUM62629.1 - 0.036 14.2 0.1 0.059 13.5 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 KUM62629.1 - 0.038 13.3 0.2 0.059 12.7 0.2 1.2 1 0 0 1 1 1 0 ThiF family adh_short PF00106.25 KUM62629.1 - 0.15 11.5 0.3 15 5.0 0.3 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Ank_2 PF12796.7 KUM62630.1 - 1.2e-74 246.9 0.0 5.9e-14 52.4 0.0 4.8 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM62630.1 - 2.7e-35 120.3 0.5 2.3e-09 37.6 0.0 5.8 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KUM62630.1 - 3.4e-34 115.8 0.6 0.00043 20.6 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KUM62630.1 - 5.3e-32 109.5 4.6 2e-07 31.1 0.1 6.0 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM62630.1 - 5.5e-28 93.9 0.0 0.034 14.7 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat ChitinaseA_N PF08329.10 KUM62630.1 - 0.092 12.4 0.0 16 5.1 0.0 3.0 1 1 2 3 3 3 0 Chitinase A, N-terminal domain DUF2384 PF09722.10 KUM62630.1 - 1.2 9.3 8.1 42 4.3 0.0 5.2 7 0 0 7 7 7 0 Protein of unknown function (DUF2384) His_Phos_1 PF00300.22 KUM62631.1 - 0.018 14.7 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) AP_endonuc_2 PF01261.24 KUM62632.1 - 2.4e-12 46.8 0.0 3.7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel F-box-like PF12937.7 KUM62633.1 - 0.0014 18.5 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like Redoxin PF08534.10 KUM62634.1 - 3e-36 124.3 0.0 3.3e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KUM62634.1 - 9.1e-13 48.2 0.0 1.2e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family MFS_1 PF07690.16 KUM62635.1 - 3.6e-23 82.1 17.4 3.9e-23 81.9 17.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KUM62635.1 - 2.9e-05 23.6 5.8 3.9e-05 23.1 5.8 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Orf78 PF06024.12 KUM62636.1 - 0.00065 20.0 0.1 0.00092 19.5 0.1 1.3 1 0 0 1 1 1 1 Orf78 (ac78) MFS_1 PF07690.16 KUM62636.1 - 0.0024 16.8 0.0 0.0029 16.6 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily AbrB PF05145.12 KUM62636.1 - 0.0037 16.3 0.6 0.0045 16.0 0.6 1.1 1 0 0 1 1 1 1 Transition state regulatory protein AbrB BT1 PF03092.16 KUM62636.1 - 0.034 12.4 0.0 0.041 12.1 0.0 1.1 1 0 0 1 1 1 0 BT1 family CCSMST1 PF15013.6 KUM62636.1 - 0.049 13.8 0.1 0.086 13.0 0.1 1.4 1 0 0 1 1 1 0 CCSMST1 family BatD PF13584.6 KUM62636.1 - 0.074 11.9 0.0 0.078 11.8 0.0 1.0 1 0 0 1 1 1 0 Oxygen tolerance DUF2407_C PF13373.6 KUM62636.1 - 0.2 11.8 0.2 4.9 7.3 0.4 2.0 2 0 0 2 2 2 0 DUF2407 C-terminal domain AI-2E_transport PF01594.16 KUM62636.1 - 0.24 10.5 4.4 0.07 12.3 0.8 1.6 1 1 0 1 1 1 0 AI-2E family transporter DUF2834 PF11196.8 KUM62636.1 - 0.26 11.7 3.3 0.37 11.2 0.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2834) Pyr_redox_2 PF07992.14 KUM62637.1 - 6.5e-09 35.4 0.0 1.5e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM62637.1 - 1.9e-07 31.2 0.0 5e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KUM62637.1 - 0.0078 15.4 0.0 0.15 11.2 0.0 2.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KUM62637.1 - 0.011 15.0 0.0 2.5 7.3 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RRM_1 PF00076.22 KUM62638.1 - 0.00022 21.0 0.1 0.083 12.7 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.11 KUM62638.1 - 1.1 9.3 31.2 9 6.3 27.1 2.5 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region SPC25 PF06703.11 KUM62640.1 - 0.1 12.4 0.1 0.14 11.9 0.0 1.3 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) UL40 PF10682.9 KUM62640.1 - 0.27 10.9 1.4 10 5.7 0.1 2.1 1 1 1 2 2 2 0 Glycoprotein of human cytomegalovirus HHV-5 Acetyltransf_3 PF13302.7 KUM62641.1 - 2.7e-17 63.7 0.1 9.3e-17 62.0 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM62641.1 - 3.1e-08 33.9 0.0 4.9e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KUM62641.1 - 0.00057 19.8 0.0 0.0016 18.3 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 KUM62641.1 - 0.001 18.8 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DAPDH_C PF16654.5 KUM62641.1 - 0.087 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain FA_desaturase PF00487.24 KUM62642.1 - 2.9e-29 102.7 26.4 6.8e-29 101.5 26.4 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF1275 PF06912.11 KUM62643.1 - 2e-05 24.6 1.5 3e-05 24.0 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4603 PF15376.6 KUM62643.1 - 0.02 12.3 0.0 0.023 12.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) CtsR PF05848.11 KUM62644.1 - 1.3 9.0 2.9 2 8.4 0.2 2.1 1 1 1 2 2 2 0 CtsR N-terminal HTH domain zf-C2H2 PF00096.26 KUM62646.1 - 8.5e-12 44.8 11.0 6.9e-06 26.2 0.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM62646.1 - 2.5e-09 37.2 9.2 0.00021 21.9 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KUM62646.1 - 1.5e-08 34.7 9.7 4.9e-06 26.7 2.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KUM62646.1 - 4.5e-05 23.1 7.8 0.0068 16.1 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KUM62646.1 - 0.0021 18.3 7.1 0.0066 16.7 0.1 2.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KUM62646.1 - 0.018 15.5 6.5 0.72 10.3 0.7 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KUM62646.1 - 0.3 11.5 0.2 0.3 11.5 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KUM62646.1 - 0.35 10.9 13.4 0.37 10.9 0.5 2.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KUM62646.1 - 0.41 10.4 3.6 5.2 6.9 0.3 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-CHY PF05495.12 KUM62646.1 - 0.58 10.7 3.4 2.1 8.9 3.5 1.7 1 1 0 1 1 1 0 CHY zinc finger zf-AN1 PF01428.16 KUM62646.1 - 4.3 7.6 8.2 19 5.5 1.9 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger GPI-anchored PF10342.9 KUM62648.1 - 1.3e-13 51.5 3.4 1.3e-13 51.5 3.4 4.1 2 2 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_3_4 PF13754.6 KUM62648.1 - 0.0026 17.4 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF572 PF04502.13 KUM62648.1 - 6.2 6.3 11.7 8.2 5.9 11.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) GREB1 PF15782.5 KUM62648.1 - 7.7 3.5 16.3 8.8 3.3 16.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1387 PF07139.11 KUM62648.1 - 7.8 6.1 15.7 10 5.8 15.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Utp14 PF04615.13 KUM62648.1 - 7.9 4.9 11.9 10 4.6 11.9 1.0 1 0 0 1 1 1 0 Utp14 protein SOG2 PF10428.9 KUM62648.1 - 8.1 5.5 31.4 10 5.1 31.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CytochromB561_N PF09786.9 KUM62648.1 - 8.4 5.2 20.3 9 5.2 20.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal NUFIP1 PF10453.9 KUM62649.1 - 1.9e-16 59.6 1.6 1.9e-16 59.6 1.6 3.4 4 0 0 4 4 4 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 KUM62649.1 - 2.9e-09 36.6 4.2 5.4e-09 35.7 4.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KUM62649.1 - 1.7e-06 27.9 7.4 2.7e-06 27.2 7.4 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KUM62649.1 - 8.3e-05 22.3 4.0 0.00013 21.6 4.0 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KUM62649.1 - 0.00016 22.3 0.1 0.00016 22.3 0.1 2.8 2 0 0 2 2 2 1 Torus domain AF-4 PF05110.13 KUM62649.1 - 0.002 16.3 9.7 0.002 16.3 9.7 2.3 1 1 0 2 2 2 1 AF-4 proto-oncoprotein zf-CCCH_2 PF14608.6 KUM62649.1 - 0.21 12.1 4.7 0.37 11.3 4.7 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Exonuc_VII_L PF02601.15 KUM62649.1 - 1.5 8.3 15.5 2.6 7.5 15.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sugar_tr PF00083.24 KUM62651.1 - 2.7e-109 366.0 16.3 3.3e-109 365.8 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM62651.1 - 1.3e-21 77.0 28.5 4.7e-21 75.1 21.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM151 PF14857.6 KUM62651.1 - 0.14 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 TMEM151 family PolyA_pol PF01743.20 KUM62653.1 - 0.36 11.3 3.4 0.18 12.3 0.3 2.1 2 0 0 2 2 2 0 Poly A polymerase head domain HAD_2 PF13419.6 KUM62654.1 - 8e-07 29.3 0.0 1.1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KUM62654.1 - 7.8e-06 26.3 0.0 1e-05 25.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KUM62654.1 - 1.4e-05 25.1 0.0 1.9e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like ORMDL PF04061.14 KUM62655.1 - 7.5e-58 194.2 3.1 9.3e-58 193.9 3.1 1.1 1 0 0 1 1 1 1 ORMDL family CH PF00307.31 KUM62657.1 - 9.1e-16 58.0 0.0 1.6e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KUM62657.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain DUF4677 PF15726.5 KUM62657.1 - 0.47 10.6 2.2 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4677) TPR_12 PF13424.6 KUM62659.1 - 0.0024 18.1 15.0 0.0028 17.9 0.7 4.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 KUM62659.1 - 0.0077 16.1 1.3 0.0077 16.1 1.3 4.2 6 0 0 6 6 6 1 Tetratricopeptide repeat FumaraseC_C PF10415.9 KUM62659.1 - 0.013 15.9 0.2 0.11 12.9 0.0 2.7 2 0 0 2 2 2 0 Fumarase C C-terminus TPR_1 PF00515.28 KUM62659.1 - 0.014 15.2 0.3 0.014 15.2 0.3 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KUM62659.1 - 0.083 13.1 0.5 0.083 13.1 0.5 5.6 6 1 0 6 6 6 0 Tetratricopeptide repeat CDC27 PF09507.10 KUM62659.1 - 0.13 11.6 6.9 1.3 8.3 3.3 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 CSN5_C PF18323.1 KUM62659.1 - 2 9.4 5.3 1.3 10.0 2.9 2.0 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Cdh1_DBD_1 PF18196.1 KUM62659.1 - 7 7.0 10.7 0.21 11.9 3.5 2.2 3 0 0 3 3 3 0 Chromodomain helicase DNA-binding domain 1 WD40 PF00400.32 KUM62662.1 - 1.6e-44 149.0 24.0 3e-09 37.4 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM62662.1 - 1.9e-09 37.7 0.4 0.049 13.9 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KUM62662.1 - 1.1e-05 24.3 5.5 0.093 11.4 0.1 4.6 2 1 3 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KUM62662.1 - 0.0044 16.0 0.1 12 4.8 0.0 3.9 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KUM62662.1 - 0.005 15.4 0.0 1.3 7.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 KUM62662.1 - 0.016 15.1 0.5 20 5.3 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KUM62662.1 - 0.046 13.0 0.0 1.1 8.5 0.0 2.3 2 1 0 2 2 2 0 WD40-like domain EMP24_GP25L PF01105.24 KUM62663.1 - 5.6e-39 134.0 0.0 7.3e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sdh5 PF03937.16 KUM62663.1 - 5.1e-22 77.6 0.1 1.4e-21 76.2 0.1 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase Piwi PF02171.17 KUM62666.1 - 1.1e-65 221.8 0.0 1.8e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 KUM62666.1 - 3e-13 49.2 0.2 7.5e-13 47.9 0.2 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 KUM62666.1 - 2.8e-12 47.4 0.0 2.5e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL2 PF16488.5 KUM62666.1 - 1.7e-09 37.9 0.1 4.1e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KUM62666.1 - 6.4e-09 35.7 0.0 1.3e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KUM62666.1 - 3.7e-06 27.1 0.0 7.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Mid domain of argonaute NDUFA12 PF05071.16 KUM62667.1 - 2.2e-10 41.2 12.0 2.8e-09 37.7 12.0 2.3 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Nucleo_P87 PF07267.11 KUM62667.1 - 0.75 8.6 12.0 0.91 8.3 12.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-CCHC PF00098.23 KUM62668.1 - 4.5e-42 140.3 52.8 3.8e-07 29.9 1.8 7.4 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KUM62668.1 - 7.9e-11 41.7 35.2 0.12 12.4 0.4 7.2 1 1 6 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KUM62668.1 - 4.8e-09 35.8 40.4 0.0092 15.7 0.1 7.1 7 0 0 7 7 7 5 Zinc knuckle zf-CCHC_2 PF13696.6 KUM62668.1 - 3.6e-06 26.7 48.0 0.0039 17.0 0.9 7.3 7 0 0 7 7 7 5 Zinc knuckle zf-CCHC_6 PF15288.6 KUM62668.1 - 1.2e-05 25.1 43.4 0.0049 16.7 0.4 7.2 6 1 1 7 7 7 4 Zinc knuckle Elf1 PF05129.13 KUM62668.1 - 0.032 14.3 34.9 0.057 13.5 4.5 4.2 2 2 2 4 4 4 0 Transcription elongation factor Elf1 like Abi_HHR PF07815.14 KUM62668.1 - 0.063 13.4 0.1 0.35 11.0 0.0 2.2 2 1 0 2 2 2 0 Abl-interactor HHR TRAF6_Z2 PF18048.1 KUM62668.1 - 5.1 7.3 8.1 48 4.2 0.4 4.4 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Sugar_tr PF00083.24 KUM62669.1 - 1e-109 367.4 23.6 1e-109 367.4 23.6 1.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM62669.1 - 7e-20 71.3 30.6 6.7e-15 54.9 7.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 KUM62669.1 - 0.12 12.9 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3464 PF11947.8 KUM62669.1 - 0.31 10.8 2.3 0.79 9.5 2.3 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF846 PF05832.12 KUM62670.1 - 4.7e-47 159.5 9.4 5.8e-47 159.2 9.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) zf-CCHC PF00098.23 KUM62671.1 - 1.9e-28 97.2 54.2 6.2e-07 29.2 3.8 6.4 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 KUM62671.1 - 7.9e-10 38.3 28.2 0.015 15.0 0.2 6.1 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_3 PF13917.6 KUM62671.1 - 1.8e-09 37.4 38.9 0.0034 17.3 0.0 6.1 2 1 3 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.6 KUM62671.1 - 0.00018 21.2 41.9 0.85 9.5 1.1 6.6 6 1 0 6 6 6 6 Zinc knuckle Gln-synt_N PF03951.19 KUM62672.1 - 9.4e-13 47.7 0.0 1.9e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain zf-CCCH_7 PF18586.1 KUM62674.1 - 0.76 10.1 4.8 30 5.0 2.3 2.7 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Gln-synt_C PF00120.24 KUM62675.1 - 3.8e-07 29.4 0.0 0.00065 18.8 0.1 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain MFS_1 PF07690.16 KUM62676.1 - 1.8e-35 122.5 48.0 6.6e-30 104.2 31.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Imm57 PF15596.6 KUM62676.1 - 5.6e-05 23.4 0.0 0.00011 22.5 0.0 1.4 1 0 0 1 1 1 1 Immunity protein 57 FPN1 PF06963.12 KUM62676.1 - 0.016 13.8 2.7 0.05 12.2 2.7 1.8 1 0 0 1 1 1 0 Ferroportin1 (FPN1) UNC-93 PF05978.16 KUM62676.1 - 0.14 11.9 5.1 0.27 10.9 4.3 1.7 1 1 0 1 1 1 0 Ion channel regulatory protein UNC-93 DUF4059 PF13268.6 KUM62676.1 - 2.9 8.4 6.5 3.6 8.1 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) Med1 PF10744.9 KUM62677.1 - 3.2e-126 421.7 0.0 4e-126 421.4 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Dynein_heavy PF03028.15 KUM62677.1 - 0.042 13.9 0.3 0.078 13.1 0.3 1.3 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain AMP-binding PF00501.28 KUM62678.1 - 7.3e-59 199.4 0.0 1.2e-58 198.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM62678.1 - 0.022 15.7 0.0 0.05 14.6 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Condensation PF00668.20 KUM62678.1 - 0.038 12.7 0.0 0.056 12.1 0.0 1.2 1 0 0 1 1 1 0 Condensation domain ABC2_membrane PF01061.24 KUM62679.1 - 3.3e-70 235.8 69.6 2.1e-37 128.6 27.2 3.7 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 KUM62679.1 - 3e-34 118.5 0.0 5.3e-16 59.4 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KUM62679.1 - 6.2e-28 96.5 0.0 6.2e-28 96.5 0.0 4.0 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KUM62679.1 - 2.9e-09 37.4 0.3 7.1e-09 36.2 0.3 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KUM62679.1 - 4.8e-08 32.5 45.0 1.5e-07 30.9 15.4 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 KUM62679.1 - 4.8e-06 26.3 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KUM62679.1 - 1.8e-05 25.3 0.1 0.0038 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KUM62679.1 - 3.8e-05 23.7 1.3 0.00098 19.1 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KUM62679.1 - 0.00018 21.9 0.3 0.0012 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KUM62679.1 - 0.00067 19.6 0.0 1.3 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KUM62679.1 - 0.00071 19.3 0.3 0.039 13.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KUM62679.1 - 0.00077 19.0 0.0 0.33 10.4 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 KUM62679.1 - 0.0012 19.1 0.1 0.015 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KUM62679.1 - 0.0046 17.4 0.5 0.73 10.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KUM62679.1 - 0.017 15.1 0.2 1.4 8.8 0.0 2.8 2 0 0 2 2 2 0 NACHT domain Pax2_C PF12403.8 KUM62679.1 - 0.039 14.0 2.7 0.068 13.3 0.7 2.4 3 0 0 3 3 2 0 Paired-box protein 2 C terminal cobW PF02492.19 KUM62679.1 - 0.045 13.4 1.2 0.17 11.4 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KUM62679.1 - 0.084 12.6 0.1 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KUM62679.1 - 0.13 12.5 0.4 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KUM62679.1 - 0.14 12.2 0.0 8.6 6.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KUM62679.1 - 0.18 11.5 0.2 19 4.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain SRAP PF02586.14 KUM62680.1 - 4.1e-79 265.2 0.2 5.8e-79 264.7 0.2 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Sigma70_ner PF04546.13 KUM62682.1 - 0.41 10.5 1.9 2.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Peptidase_S9 PF00326.21 KUM62684.1 - 5.9e-53 179.5 0.4 2.4e-52 177.5 0.1 2.1 3 0 0 3 3 3 1 Prolyl oligopeptidase family PD40 PF07676.12 KUM62684.1 - 7.5e-06 25.7 1.1 0.037 14.0 0.0 4.0 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat COesterase PF00135.28 KUM62684.1 - 2e-05 23.7 0.0 3.1e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9_N PF02897.15 KUM62684.1 - 0.12 11.2 2.3 0.15 10.8 0.1 2.1 3 0 0 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Glyco_transf_90 PF05686.12 KUM62685.1 - 7.2e-12 44.9 0.3 0.0018 17.3 0.0 3.9 3 1 0 3 3 3 3 Glycosyl transferase family 90 Vps8 PF12816.7 KUM62686.1 - 1.5e-63 213.9 0.0 3.2e-63 212.9 0.0 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KUM62686.1 - 2.7e-07 30.6 0.0 0.0066 16.3 0.0 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 KUM62686.1 - 0.0057 16.7 0.7 0.0057 16.7 0.7 2.5 3 0 0 3 3 3 1 Zinc-finger Pox_D3 PF04580.13 KUM62686.1 - 0.02 14.5 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein zf-RING_11 PF17123.5 KUM62686.1 - 0.19 11.5 0.2 0.61 9.9 0.2 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 KUM62686.1 - 0.24 11.4 1.4 0.34 10.9 0.1 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KUM62686.1 - 0.42 10.5 0.0 0.42 10.5 0.0 2.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Lipase_GDSL_2 PF13472.6 KUM62687.1 - 1.6e-23 84.1 0.0 6.9e-23 81.9 0.0 2.0 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KUM62687.1 - 6.2e-16 59.0 0.0 7.7e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KUM62687.1 - 0.19 11.8 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family SNase PF00565.17 KUM62688.1 - 1.1e-20 74.0 0.0 1.6e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Voltage_CLC PF00654.20 KUM62689.1 - 1.1e-89 301.1 25.8 6.1e-89 298.7 21.7 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel PqiA PF04403.13 KUM62689.1 - 0.0028 17.5 2.7 0.011 15.6 1.5 2.6 2 1 0 2 2 2 1 Paraquat-inducible protein A TAT_signal PF10518.9 KUM62689.1 - 5.3 7.1 7.0 1 9.3 1.2 2.8 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence DHFR_1 PF00186.19 KUM62690.1 - 3.8e-19 69.0 0.0 3.6e-13 49.5 0.0 2.5 2 1 0 2 2 2 2 Dihydrofolate reductase HK PF02110.15 KUM62691.1 - 1.2e-72 244.3 0.0 2.4e-72 243.3 0.0 1.5 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KUM62691.1 - 3.4e-60 202.5 2.1 5e-60 201.9 2.1 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 KUM62691.1 - 0.00019 21.0 0.2 0.00057 19.4 0.1 1.8 2 0 0 2 2 2 1 Carbohydrate kinase eIF-5_eIF-2B PF01873.17 KUM62692.1 - 7e-39 132.3 0.0 1.5e-38 131.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KUM62692.1 - 8e-21 74.0 0.1 2.1e-20 72.7 0.1 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon GNAT_acetyltr_2 PF13718.6 KUM62696.1 - 8.5e-98 326.3 0.0 1.5e-97 325.5 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KUM62696.1 - 1.1e-82 277.3 0.1 1.8e-82 276.6 0.1 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KUM62696.1 - 2.1e-65 219.9 0.0 7.8e-65 218.0 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KUM62696.1 - 4.3e-35 119.5 0.0 1.1e-34 118.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KUM62696.1 - 0.00068 19.4 0.0 0.031 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KUM62696.1 - 0.011 16.1 0.0 0.033 14.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 KUM62696.1 - 0.013 15.7 0.0 0.053 13.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family AAA_22 PF13401.6 KUM62696.1 - 0.024 14.9 0.1 0.84 9.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain GHMP_kinases_N PF00288.26 KUM62696.1 - 0.097 12.9 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 GHMP kinases N terminal domain ADH_zinc_N PF00107.26 KUM62697.1 - 5.8e-13 49.0 0.0 1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase F-box PF00646.33 KUM62697.1 - 1.1e-06 28.3 0.1 2.6e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 F-box domain ADH_zinc_N_2 PF13602.6 KUM62697.1 - 1.3e-06 29.5 0.0 2.9e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase F-box-like PF12937.7 KUM62697.1 - 4.9e-05 23.1 0.3 0.00014 21.7 0.3 1.8 1 0 0 1 1 1 1 F-box-like ADH_N PF08240.12 KUM62697.1 - 0.00089 19.1 0.3 0.0022 17.9 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thioredoxin PF00085.20 KUM62698.1 - 6e-31 106.5 0.1 5.2e-26 90.6 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KUM62698.1 - 5e-08 33.4 0.6 0.00071 20.0 0.1 2.5 1 1 1 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KUM62698.1 - 3.3e-07 30.0 0.0 3.7e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KUM62698.1 - 0.0025 17.7 0.0 0.0062 16.5 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KUM62698.1 - 0.003 17.7 0.0 0.0068 16.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 KUM62698.1 - 0.0055 17.0 0.1 2.2 8.7 0.1 3.3 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.6 KUM62698.1 - 0.0093 16.0 1.9 0.85 9.7 0.1 2.6 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_6 PF13848.6 KUM62698.1 - 0.041 13.8 0.0 3.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain Glutaredoxin PF00462.24 KUM62698.1 - 0.17 12.1 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin TraF PF13728.6 KUM62698.1 - 0.18 11.6 0.0 0.18 11.6 0.0 3.3 3 1 1 4 4 4 0 F plasmid transfer operon protein ADH_zinc_N PF00107.26 KUM62700.1 - 4.8e-09 36.3 0.3 8.1e-09 35.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM62700.1 - 4e-06 26.7 0.0 8.7e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KUM62700.1 - 0.13 12.1 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Glyco_hydro_16 PF00722.21 KUM62701.1 - 3e-09 36.6 0.0 8.7e-09 35.1 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Nop14 PF04147.12 KUM62702.1 - 0.011 14.0 1.5 0.089 11.0 0.0 2.1 2 0 0 2 2 2 0 Nop14-like family DNA_ligase_A_M PF01068.21 KUM62703.1 - 3.8e-59 199.8 0.4 3.5e-57 193.4 0.4 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KUM62703.1 - 2.2e-44 151.8 0.0 4.1e-44 150.9 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KUM62703.1 - 1.7e-26 92.7 0.0 9e-26 90.4 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KUM62703.1 - 1.9e-05 25.0 0.1 3.4e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 RNA ligase Isochorismatase PF00857.20 KUM62704.1 - 4.2e-29 102.0 0.0 5.2e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Med22 PF06179.12 KUM62705.1 - 2.6e-17 62.9 0.1 2.6e-17 62.9 0.1 1.7 2 0 0 2 2 2 1 Surfeit locus protein 5 subunit 22 of Mediator complex Arg_decarbox_C PF17944.1 KUM62705.1 - 0.087 13.4 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension PG_binding_1 PF01471.18 KUM62705.1 - 0.55 10.5 2.5 7.5 6.8 0.3 3.1 2 2 1 3 3 3 0 Putative peptidoglycan binding domain Apc13p PF05839.11 KUM62706.1 - 0.046 13.9 0.2 17 5.7 0.0 2.7 2 1 0 2 2 2 0 Apc13p protein ADK PF00406.22 KUM62707.1 - 2.6e-34 118.5 0.0 2.5e-19 69.9 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 KUM62707.1 - 1.1e-15 57.2 0.0 1.8e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KUM62707.1 - 5.5e-14 52.8 0.0 1.4e-09 38.5 0.0 2.5 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KUM62707.1 - 1.7e-05 25.4 0.0 8.6e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KUM62707.1 - 0.0025 18.0 0.1 0.045 13.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain DUF3446 PF11928.8 KUM62707.1 - 0.011 16.0 6.4 0.019 15.3 6.4 1.3 1 0 0 1 1 1 0 Early growth response N-terminal domain AAA_5 PF07728.14 KUM62707.1 - 0.11 12.5 0.2 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KUM62707.1 - 0.12 12.7 0.0 0.25 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KUM62707.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KUM62707.1 - 0.22 10.5 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB adh_short PF00106.25 KUM62708.1 - 2.2e-21 76.2 0.0 3.4e-16 59.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM62708.1 - 4e-13 49.5 0.0 5.9e-11 42.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM62708.1 - 0.00077 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM62708.1 - 0.051 13.0 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KUM62708.1 - 0.19 11.8 0.0 0.43 10.6 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase KR PF08659.10 KUM62709.1 - 1.1e-56 191.6 0.0 1.7e-56 190.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KUM62709.1 - 4.4e-12 45.9 0.0 7.7e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM62709.1 - 6.5e-08 32.4 0.0 1.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KUM62709.1 - 2.6e-06 27.7 0.1 4.9e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 KUM62709.1 - 0.041 13.3 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ATP-synt PF00231.19 KUM62710.1 - 1.7e-75 254.4 6.8 2e-75 254.1 6.8 1.0 1 0 0 1 1 1 1 ATP synthase DnaJ PF00226.31 KUM62711.1 - 5.4e-18 64.9 0.1 1.3e-17 63.6 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Epimerase PF01370.21 KUM62712.1 - 7.2e-18 64.9 0.0 1.1e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM62712.1 - 2.8e-07 30.2 0.0 6.1e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KUM62712.1 - 5e-07 29.0 0.0 1.3e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KUM62712.1 - 4.7e-06 25.9 0.0 6.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Ldh_1_N PF00056.23 KUM62712.1 - 0.0078 16.3 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 KUM62712.1 - 0.014 14.8 0.0 0.036 13.5 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.10 KUM62712.1 - 0.056 13.3 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 KR domain Topoisom_I_N PF02919.15 KUM62713.1 - 6.8e-96 319.9 3.0 6.8e-96 319.9 3.0 4.1 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 KUM62713.1 - 3.7e-94 314.3 9.5 3.7e-94 314.3 9.5 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 KUM62713.1 - 8.4e-34 115.3 1.0 3.5e-33 113.4 1.0 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain Peptidase_C2 PF00648.21 KUM62714.1 - 4.2e-29 101.5 0.0 6.9e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KUM62714.1 - 1.3e-10 41.7 0.0 1.1e-06 29.0 0.0 3.5 3 1 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.18 KUM62714.1 - 0.49 10.5 3.8 0.87 9.7 3.8 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Vta1 PF04652.16 KUM62715.1 - 8.8e-49 165.2 0.1 1.3e-48 164.6 0.1 1.3 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 KUM62715.1 - 9.8e-17 60.4 0.0 2.1e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Vta1 C-terminal domain Mito_carr PF00153.27 KUM62717.1 - 7.2e-54 179.7 1.2 5e-19 68.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GYF PF02213.16 KUM62718.1 - 3.5e-11 42.6 2.1 8.7e-11 41.3 2.1 1.7 1 0 0 1 1 1 1 GYF domain NusB PF01029.18 KUM62718.1 - 1.2 9.4 5.6 9.2 6.5 0.8 2.5 2 0 0 2 2 2 0 NusB family UFD1 PF03152.14 KUM62719.1 - 1.4e-74 249.3 0.0 1.7e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 KUM62719.1 - 0.0017 18.1 0.0 0.044 13.6 0.0 2.3 1 1 1 2 2 2 1 Cell division protein 48 (CDC48), domain 2 DUF829 PF05705.14 KUM62720.1 - 7e-31 108.0 0.0 7.9e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF4246 PF14033.6 KUM62721.1 - 1.2e-140 469.6 0.6 1.5e-140 469.3 0.2 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4246) RNA_pol_Rpb2_6 PF00562.28 KUM62722.1 - 1.2e-121 406.5 0.1 1.2e-121 406.5 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KUM62722.1 - 5.4e-55 186.1 0.6 8.3e-55 185.4 0.6 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KUM62722.1 - 6.7e-33 113.0 2.7 1.4e-32 112.0 0.3 2.8 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KUM62722.1 - 2.1e-28 99.3 3.5 4.1e-28 98.3 3.5 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KUM62722.1 - 2.5e-24 85.3 1.8 4.8e-24 84.4 0.6 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KUM62722.1 - 1.3e-19 70.1 0.4 4.1e-19 68.5 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KUM62722.1 - 1.1e-11 45.1 0.6 3.4e-11 43.5 0.6 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 NRDD PF13597.6 KUM62722.1 - 0.0046 15.8 0.2 0.084 11.6 0.1 2.1 2 0 0 2 2 2 1 Anaerobic ribonucleoside-triphosphate reductase PUF PF00806.19 KUM62724.1 - 9e-60 195.1 10.4 3e-07 29.7 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat MgtE_N PF03448.17 KUM62724.1 - 0.041 14.5 0.0 0.17 12.5 0.1 2.0 2 0 0 2 2 2 0 MgtE intracellular N domain Bestrophin PF01062.21 KUM62725.1 - 0.016 14.6 3.1 0.28 10.5 0.1 2.8 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel DUF1852 PF08908.11 KUM62725.1 - 0.018 14.0 1.7 0.49 9.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1852) Baculo_PEP_C PF04513.12 KUM62725.1 - 0.022 14.8 59.5 0.3 11.1 3.1 7.6 2 2 4 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus DPM3 PF08285.11 KUM62725.1 - 0.1 12.8 1.2 0.44 10.8 0.1 2.6 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1664 PF07889.12 KUM62725.1 - 0.24 11.4 60.2 0.31 11.1 1.6 9.5 3 3 6 10 10 10 0 Protein of unknown function (DUF1664) Vps54 PF07928.12 KUM62725.1 - 3.6 8.0 7.6 3.5 8.1 0.1 3.9 3 0 0 3 3 3 0 Vps54-like protein TIP49 PF06068.13 KUM62726.1 - 1.8e-153 510.9 3.0 2.5e-153 510.4 3.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KUM62726.1 - 3.4e-21 75.1 0.3 1.1e-20 73.5 0.3 2.0 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KUM62726.1 - 3.9e-09 37.0 0.7 8.5e-06 26.2 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KUM62726.1 - 4.4e-08 33.0 0.4 6.9e-05 22.7 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KUM62726.1 - 1.5e-06 28.7 0.2 5.4e-06 26.9 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 KUM62726.1 - 2.5e-06 27.0 0.9 5.3e-06 26.0 0.9 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 KUM62726.1 - 0.0011 18.4 0.8 0.012 15.1 0.5 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KUM62726.1 - 0.0086 15.8 0.0 5.4 6.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 KUM62726.1 - 0.014 15.7 2.3 0.23 11.8 2.3 2.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KUM62726.1 - 0.027 14.5 0.2 0.92 9.5 0.0 2.8 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KUM62726.1 - 0.04 14.2 0.0 0.092 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KUM62726.1 - 0.04 13.7 0.6 0.15 11.8 0.6 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KUM62726.1 - 0.043 13.4 0.1 0.099 12.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KUM62726.1 - 0.059 12.9 0.2 0.46 10.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KUM62726.1 - 0.061 12.4 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TFIID-31kDa PF02291.15 KUM62726.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Abp2 PF09441.10 KUM62728.1 - 3e-85 284.6 0.0 4.7e-85 283.9 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 TAF1D PF15333.6 KUM62728.1 - 0.1 12.3 0.6 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D Med9 PF07544.13 KUM62728.1 - 0.29 11.3 2.3 0.29 11.2 0.5 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Surfac_D-trimer PF09006.11 KUM62728.1 - 0.35 10.8 1.3 0.73 9.8 1.3 1.5 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation HTH_11 PF08279.12 KUM62730.1 - 0.056 13.4 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 HTH domain Sigma70_r4_2 PF08281.12 KUM62730.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_5 PF01022.20 KUM62730.1 - 0.14 12.0 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family PBP1_TM PF14812.6 KUM62730.1 - 0.5 10.8 3.5 0.78 10.2 3.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 KUM62731.1 - 0.16 11.8 8.4 0.19 11.5 8.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein F-box-like PF12937.7 KUM62732.1 - 0.00051 19.9 1.7 0.0012 18.7 1.7 1.7 1 0 0 1 1 1 1 F-box-like DHC_N2 PF08393.13 KUM62732.1 - 0.062 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 LRR_4 PF12799.7 KUM62732.1 - 0.19 12.2 11.4 0.14 12.6 0.5 4.2 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KUM62732.1 - 3 8.7 4.9 61 4.8 1.2 3.9 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_8 PF13855.6 KUM62732.1 - 8.5 6.2 9.9 35 4.2 4.4 3.3 1 1 2 3 3 3 0 Leucine rich repeat WW PF00397.26 KUM62733.1 - 1.9e-05 24.6 3.6 6.3e-05 23.0 3.6 2.0 1 0 0 1 1 1 1 WW domain ORC5_C PF14630.6 KUM62735.1 - 2.2e-86 289.9 0.0 2.9e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KUM62735.1 - 2.7e-16 60.4 0.1 8.6e-16 58.8 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 KUM62735.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Git3 PF11710.8 KUM62736.1 - 1e-08 35.2 10.4 2.5e-08 33.9 10.4 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 KUM62736.1 - 3.4e-08 33.0 10.7 1.2e-06 27.9 7.6 2.0 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KUM62736.1 - 2.1e-07 30.6 5.1 2.9e-07 30.1 5.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KUM62736.1 - 0.00016 21.1 8.4 0.00023 20.6 8.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF1849 PF08904.11 KUM62736.1 - 0.0069 16.0 0.5 0.01 15.4 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1849) Shisa PF13908.6 KUM62736.1 - 0.018 15.3 0.1 0.027 14.7 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Frizzled PF01534.17 KUM62736.1 - 0.18 10.8 11.9 3.9 6.4 10.1 2.6 2 1 0 2 2 2 0 Frizzled/Smoothened family membrane region FixQ PF05545.11 KUM62736.1 - 1.4 9.0 7.9 0.99 9.4 0.2 3.2 3 1 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF3671 PF12420.8 KUM62736.1 - 3.7 7.7 6.1 14 5.7 3.9 2.3 2 0 0 2 2 2 0 Protein of unknown function ABC_tran PF00005.27 KUM62738.1 - 2.6e-25 89.5 0.0 5.4e-25 88.5 0.0 1.5 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 KUM62738.1 - 7.5e-17 61.9 3.1 7.5e-17 61.9 3.1 1.6 1 1 1 2 2 2 1 ABC transporter transmembrane region AAA_29 PF13555.6 KUM62738.1 - 0.042 13.6 0.1 0.098 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KUM62738.1 - 0.044 13.9 0.1 0.088 12.9 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 KUM62738.1 - 0.14 12.2 0.2 0.22 11.6 0.2 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 KUM62738.1 - 0.15 12.5 0.1 0.31 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF2244 PF10003.9 KUM62738.1 - 0.21 11.2 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) E1-E2_ATPase PF00122.20 KUM62740.1 - 2.1e-42 144.7 5.2 2.1e-42 144.7 5.2 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KUM62740.1 - 1.5e-16 61.3 0.1 3.5e-16 60.1 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KUM62740.1 - 2.6e-11 43.1 0.0 8.2e-11 41.4 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KUM62740.1 - 0.0035 17.1 0.1 0.0097 15.7 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_M20 PF01546.28 KUM62742.1 - 3.4e-09 36.7 0.2 5.9e-09 35.9 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KUM62742.1 - 2.1e-05 24.4 0.0 5.2e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Abhydrolase_1 PF00561.20 KUM62743.1 - 7.2e-28 97.9 0.0 6e-22 78.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KUM62743.1 - 1.2e-13 52.1 0.0 1.7e-13 51.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM62743.1 - 2.8e-12 46.4 0.0 5.2e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KUM62743.1 - 5.4e-08 33.2 0.1 1.4e-07 31.9 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 KUM62743.1 - 1.7e-07 31.2 0.1 9.8e-06 25.5 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KUM62743.1 - 8.5e-06 25.8 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KUM62743.1 - 0.00053 19.0 0.0 0.0015 17.5 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KUM62743.1 - 0.00077 18.6 0.0 0.0022 17.1 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase Esterase PF00756.20 KUM62743.1 - 0.0012 18.6 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 KUM62743.1 - 0.0042 15.8 0.0 0.0087 14.8 0.0 1.5 1 0 0 1 1 1 1 Ndr family LIDHydrolase PF10230.9 KUM62743.1 - 0.0046 16.6 0.0 0.014 14.9 0.0 1.7 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 KUM62743.1 - 0.0081 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 KUM62743.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Ser_hydrolase PF06821.13 KUM62743.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_5 PF12695.7 KUM62743.1 - 0.033 13.9 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF3530 PF12048.8 KUM62743.1 - 0.049 13.0 0.0 0.072 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF2974 PF11187.8 KUM62743.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) EHN PF06441.12 KUM62744.1 - 2.5e-37 127.5 2.1 1.8e-36 124.8 0.2 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KUM62744.1 - 7.4e-09 35.6 0.1 1.4e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KUM62744.1 - 0.00014 22.5 3.1 0.00022 21.9 3.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family CW_7 PF08230.11 KUM62744.1 - 0.13 12.1 0.1 0.34 10.7 0.1 1.7 1 0 0 1 1 1 0 CW_7 repeat DUF3224 PF11528.8 KUM62745.1 - 0.02 14.7 0.0 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3224) Period_C PF12114.8 KUM62745.1 - 1.2 8.6 11.4 0.092 12.3 6.2 1.6 2 0 0 2 2 2 0 Period protein 2/3C-terminal region DUF515 PF04415.12 KUM62745.1 - 3.1 6.1 9.1 5.3 5.3 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) B12-binding PF02310.19 KUM62746.1 - 0.0013 18.8 0.1 0.0018 18.3 0.1 1.2 1 0 0 1 1 1 1 B12 binding domain FtsK_SpoIIIE PF01580.18 KUM62746.1 - 0.0056 16.1 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family FAA_hydrolase PF01557.18 KUM62747.1 - 2.8e-53 180.8 0.0 3.7e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.16 KUM62748.1 - 3.2e-40 138.1 26.8 4.6e-40 137.6 26.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM62748.1 - 1.2e-13 50.8 5.6 1.2e-13 50.8 5.6 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KUM62748.1 - 1.1e-06 27.5 3.6 1.3e-05 23.9 2.2 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Gly-zipper_Omp PF13488.6 KUM62748.1 - 0.19 11.8 2.6 13 5.8 0.5 3.0 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.15 KUM62748.1 - 0.22 11.4 1.7 12 5.9 0.5 2.8 2 0 0 2 2 2 0 Glycine zipper 2TM domain Phage_holin_3_7 PF05449.11 KUM62748.1 - 0.26 11.3 1.9 9.8 6.3 0.1 3.6 4 0 0 4 4 4 0 Putative 3TM holin, Phage_holin_3 zf-C2H2 PF00096.26 KUM62749.1 - 2e-08 34.2 11.4 3.2e-05 24.1 0.4 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KUM62749.1 - 2.6e-06 27.5 2.1 0.075 13.4 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KUM62749.1 - 6.9e-06 26.5 11.7 0.0016 19.1 0.3 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KUM62749.1 - 2.8e-05 24.3 5.8 2.8e-05 24.3 5.8 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KUM62749.1 - 0.00022 21.1 10.2 0.015 15.2 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KUM62749.1 - 0.0038 17.5 2.0 0.41 11.1 0.2 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type C1_4 PF07975.12 KUM62749.1 - 0.035 14.3 2.3 0.068 13.4 2.3 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain Syd PF07348.12 KUM62749.1 - 0.11 12.1 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Syd protein (SUKH-2) zf-C2H2_11 PF16622.5 KUM62749.1 - 0.17 11.6 3.8 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-Paramyx-P PF13008.7 KUM62749.1 - 0.3 10.6 3.0 0.49 9.9 3.0 1.3 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein zf-MYST PF17772.1 KUM62749.1 - 0.34 10.5 3.4 7.6 6.2 0.1 2.4 1 1 1 2 2 2 0 MYST family zinc finger domain RIG-I_C-RD PF11648.8 KUM62749.1 - 0.41 10.9 2.5 8.6 6.6 1.4 2.3 2 0 0 2 2 2 0 C-terminal domain of RIG-I zf_C2H2_ZHX PF18387.1 KUM62749.1 - 3.4 7.4 8.2 13 5.5 0.5 2.9 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Fungal_trans PF04082.18 KUM62750.1 - 4.6e-06 25.9 0.4 9.6e-06 24.8 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain ORC6 PF05460.13 KUM62752.1 - 0.0035 16.7 6.6 0.0037 16.6 6.6 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Cys_Met_Meta_PP PF01053.20 KUM62753.1 - 4.4e-141 469.8 0.1 5e-141 469.7 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KUM62753.1 - 5.8e-09 35.6 0.1 8.3e-09 35.1 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KUM62753.1 - 6.9e-08 32.2 0.3 1.2e-07 31.4 0.3 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KUM62753.1 - 9e-07 28.2 1.1 1.4e-06 27.5 0.4 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KUM62753.1 - 0.00011 21.6 0.2 0.00018 20.9 0.2 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase RNA_pol_Rbc25 PF08292.12 KUM62754.1 - 5e-30 104.4 0.1 8.3e-30 103.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KUM62754.1 - 9.2e-14 51.6 0.0 1.5e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 MFS_1 PF07690.16 KUM62755.1 - 3.4e-41 141.3 49.7 3.4e-41 141.3 49.7 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KUM62755.1 - 0.0005 18.8 6.3 0.0005 18.8 6.3 3.5 3 1 1 4 4 4 2 MFS/sugar transport protein Fungal_trans_2 PF11951.8 KUM62756.1 - 2e-13 49.9 0.8 1.8e-12 46.8 0.8 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.25 KUM62757.1 - 3.2e-08 33.8 0.0 3.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KUM62757.1 - 8.1e-08 32.1 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KUM62757.1 - 3.6e-07 30.5 0.0 5.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KUM62757.1 - 4.3e-06 26.7 0.0 6.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KUM62757.1 - 0.0022 18.1 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KUM62757.1 - 0.04 14.6 0.0 0.061 14.0 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain TFIIA_gamma_N PF02268.16 KUM62759.1 - 0.13 12.3 0.0 10 6.2 0.1 3.0 3 0 0 3 3 3 0 Transcription initiation factor IIA, gamma subunit, helical domain DAO PF01266.24 KUM62760.1 - 2.7e-35 122.6 0.2 3e-35 122.4 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KUM62760.1 - 2.4e-05 23.7 1.8 2.4e-05 23.7 0.0 1.9 3 0 0 3 3 3 1 Thi4 family NAD_binding_8 PF13450.6 KUM62760.1 - 0.0001 22.5 0.0 0.00026 21.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KUM62760.1 - 0.067 12.3 0.0 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain OTU PF02338.19 KUM62761.1 - 2.9e-09 37.5 0.1 5.8e-09 36.5 0.1 1.5 1 1 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.16 KUM62761.1 - 0.0015 18.2 0.1 0.0037 16.9 0.0 1.7 2 0 0 2 2 2 1 CUE domain DMA PF03474.14 KUM62761.1 - 0.026 14.1 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 DMRTA motif Peptidase_C65 PF10275.9 KUM62761.1 - 0.027 13.9 0.0 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase C65 Otubain UBA_4 PF14555.6 KUM62761.1 - 0.062 13.1 0.0 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 UBA-like domain DUF1296 PF06972.11 KUM62761.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) GATase PF00117.28 KUM62762.1 - 4.5e-11 42.9 0.0 6.3e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KUM62762.1 - 0.0029 17.2 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain COPI_assoc PF08507.10 KUM62763.1 - 2.3e-31 108.5 5.3 2.5e-31 108.4 5.3 1.0 1 0 0 1 1 1 1 COPI associated protein Cytochrom_B558a PF05038.13 KUM62763.1 - 0.052 13.1 1.1 0.099 12.2 1.1 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Cg6151-P PF10233.9 KUM62763.1 - 0.47 10.8 6.3 1.2 9.4 6.0 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein CG6151-P DUF2892 PF11127.8 KUM62763.1 - 8.6 6.5 14.9 2.2 8.4 4.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2892) MFS_1 PF07690.16 KUM62764.1 - 2.7e-37 128.5 22.5 4.9e-35 121.1 19.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KUM62764.1 - 2e-13 49.7 11.8 6.4e-08 31.6 0.5 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein Mem_trans PF03547.18 KUM62764.1 - 0.00092 17.7 0.0 0.0017 16.8 0.0 1.4 1 0 0 1 1 1 1 Membrane transport protein OATP PF03137.20 KUM62764.1 - 0.069 11.4 3.9 0.22 9.8 2.5 2.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KUM62764.1 - 9.4 4.5 17.5 0.045 12.2 2.5 2.4 2 1 0 3 3 3 0 Transmembrane secretion effector DUF3716 PF12511.8 KUM62765.1 - 6.3e-10 38.9 2.5 9.3e-10 38.4 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) p450 PF00067.22 KUM62769.1 - 3.5e-46 157.9 0.0 3.9e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4335 PF14233.6 KUM62769.1 - 0.14 12.1 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) Phage_holin_3_6 PF07332.11 KUM62770.1 - 2.5 8.2 8.0 0.25 11.4 2.7 1.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III FAD_binding_3 PF01494.19 KUM62771.1 - 6.6e-16 58.5 0.0 1.4e-08 34.4 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KUM62771.1 - 5.8e-06 26.5 0.1 1.4e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM62771.1 - 3.3e-05 23.3 0.0 0.17 11.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM62771.1 - 0.00049 19.8 0.1 0.0019 17.8 0.0 1.8 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KUM62771.1 - 0.0029 18.1 0.0 0.32 11.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KUM62771.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Acyltransferase PF01553.21 KUM62773.1 - 2.7e-16 59.4 0.0 5e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Pantoate_ligase PF02569.15 KUM62774.1 - 2.8e-90 302.2 0.0 3.2e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase ATP-sulfurylase PF01747.17 KUM62774.1 - 0.2 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 ATP-sulfurylase Cellulase PF00150.18 KUM62775.1 - 1.7e-17 63.8 6.1 2.3e-17 63.4 6.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KUM62775.1 - 0.00027 20.2 1.1 0.00034 19.8 0.4 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KUM62775.1 - 0.00029 20.3 0.2 0.044 13.1 0.2 2.1 2 0 0 2 2 2 2 Beta-galactosidase DUF2255 PF10012.9 KUM62775.1 - 0.075 13.2 0.2 0.2 11.8 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) TFX_C PF14601.6 KUM62775.1 - 0.19 11.8 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term Filament PF00038.21 KUM62777.1 - 6.2e-05 22.7 66.9 6.4e-05 22.7 55.4 2.6 1 1 1 2 2 2 2 Intermediate filament protein DUF3584 PF12128.8 KUM62777.1 - 0.96 6.9 70.9 0.069 10.7 10.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 KUM62777.1 - 3.8 7.6 25.0 1.4 9.0 5.4 4.5 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 KUM62777.1 - 8.1 6.5 85.1 14 5.8 28.2 4.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Methyltransf_16 PF10294.9 KUM62779.1 - 0.0013 18.5 0.0 0.7 9.6 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase DEAD PF00270.29 KUM62781.1 - 2.6e-44 151.1 0.1 3.8e-44 150.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM62781.1 - 6.4e-19 68.3 0.0 2.3e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KUM62781.1 - 3.3e-18 65.6 0.0 6.4e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KUM62781.1 - 2.8e-06 27.4 0.2 1e-05 25.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KUM62781.1 - 0.035 13.3 0.6 0.08 12.1 0.0 1.8 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase FAM176 PF14851.6 KUM62781.1 - 0.14 11.8 6.4 0.13 11.9 0.3 3.1 3 0 0 3 3 3 0 FAM176 family DUF4611 PF15387.6 KUM62781.1 - 3.7 7.8 12.0 0.73 10.1 3.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) WD40 PF00400.32 KUM62782.1 - 6.3e-13 49.0 8.8 0.021 15.7 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM62782.1 - 0.0031 17.8 0.1 2.8 8.3 0.0 4.2 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nitroreductase PF00881.24 KUM62783.1 - 0.015 15.4 0.0 0.017 15.2 0.0 1.1 1 0 0 1 1 1 0 Nitroreductase family Nitroreductase PF00881.24 KUM62784.1 - 5.9e-06 26.4 0.0 7.3e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family ketoacyl-synt PF00109.26 KUM62786.1 - 4.2e-55 187.1 0.6 5e-55 186.8 0.6 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 KUM62786.1 - 5.6e-05 22.6 0.1 7.3e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain MFS_1 PF07690.16 KUM62787.1 - 9.8e-32 110.2 33.1 9.8e-32 110.2 33.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KUM62788.1 - 1.1e-26 93.6 47.2 1.1e-26 93.6 47.2 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily GATA PF00320.27 KUM62789.1 - 4e-28 96.7 17.5 2.3e-14 52.7 6.1 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KUM62789.1 - 1.1e-05 24.8 2.7 0.0061 16.1 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KUM62789.1 - 0.00011 22.2 2.5 0.1 12.7 0.2 2.9 2 0 0 2 2 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 KUM62789.1 - 0.0015 18.7 6.4 0.024 14.8 0.5 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.11 KUM62789.1 - 0.01 15.8 8.9 0.076 12.9 0.4 2.7 3 0 0 3 3 2 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.17 KUM62789.1 - 0.014 15.3 4.2 2 8.3 0.3 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Ribosomal_S27e PF01667.17 KUM62789.1 - 0.042 13.6 0.7 2.3 8.0 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein S27 ArfGap PF01412.18 KUM62789.1 - 0.085 12.9 3.8 0.57 10.3 0.2 2.3 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DZR PF12773.7 KUM62789.1 - 0.094 12.8 12.7 1.2 9.2 0.3 3.0 2 1 0 2 2 2 0 Double zinc ribbon CCDC-167 PF15188.6 KUM62789.1 - 0.28 11.5 1.6 0.49 10.8 1.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Nudix_N_2 PF14803.6 KUM62789.1 - 8.4 6.4 11.7 10 6.1 2.7 3.5 2 1 1 3 3 3 0 Nudix N-terminal PGA_cap PF09587.10 KUM62790.1 - 4.5e-66 222.9 0.0 7.7e-66 222.2 0.0 1.4 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap SH3_7 PF12914.7 KUM62790.1 - 0.15 12.3 0.0 0.44 10.7 0.0 1.8 1 0 0 1 1 1 0 SH3 domain of SH3b2 type Methyltransf_2 PF00891.18 KUM62791.1 - 1.5e-20 73.4 0.0 2.3e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain FAD_binding_3 PF01494.19 KUM62792.1 - 6e-09 35.6 0.2 9.8e-07 28.3 0.4 2.9 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KUM62792.1 - 2e-08 34.4 0.6 1e-07 32.1 0.5 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM62792.1 - 1e-05 24.9 0.4 0.0038 16.5 0.7 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM62792.1 - 0.00076 18.7 2.1 0.0011 18.2 2.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KUM62792.1 - 0.0014 18.3 0.8 0.0027 17.4 0.7 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KUM62792.1 - 0.003 16.5 0.6 1.3 7.8 1.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 KUM62792.1 - 0.014 15.9 0.6 0.037 14.6 0.6 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KUM62792.1 - 0.03 13.0 0.7 0.044 12.5 0.7 1.2 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KUM62792.1 - 0.086 12.1 0.6 0.15 11.3 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KUM62792.1 - 0.27 10.2 1.4 0.44 9.6 1.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KUM62792.1 - 0.28 11.1 0.7 0.7 9.7 0.6 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 KUM62794.1 - 8.7e-34 117.0 34.9 5.3e-33 114.4 36.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Holin_BhlA PF10960.8 KUM62794.1 - 0.0068 16.4 0.1 0.018 15.0 0.1 1.7 1 0 0 1 1 1 1 BhlA holin family PMP1_2 PF08114.11 KUM62794.1 - 0.042 13.6 0.3 0.042 13.6 0.3 2.9 3 0 0 3 3 3 0 ATPase proteolipid family Pkinase PF00069.25 KUM62795.1 - 8.1e-67 225.3 0.0 9.6e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM62795.1 - 3.2e-31 108.6 0.0 4.5e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KUM62795.1 - 0.0099 14.9 0.0 0.025 13.5 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KUM62795.1 - 0.1 12.2 0.1 10 5.7 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 2-Hacid_dh PF00389.30 KUM62797.1 - 4.4e-31 107.3 0.0 5.2e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Amdase PF17645.1 KUM62797.1 - 0.032 13.9 0.2 0.045 13.4 0.2 1.2 1 0 0 1 1 1 0 Arylmalonate decarboxylase 2-Hacid_dh_C PF02826.19 KUM62797.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KUM62798.1 - 4.3e-34 117.4 0.0 6.9e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ACT PF01842.25 KUM62798.1 - 0.00086 19.0 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 ACT domain 2-Hacid_dh PF00389.30 KUM62798.1 - 0.0027 17.3 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain P5-ATPase PF12409.8 KUM62799.1 - 1.6e-39 134.8 0.3 1e-38 132.2 0.0 2.2 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KUM62799.1 - 1e-14 54.4 0.0 2.6e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KUM62799.1 - 0.0037 16.9 0.0 0.0067 16.1 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus NAP PF00956.18 KUM62800.1 - 1.5e-98 329.3 8.7 1.5e-98 329.3 8.7 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Afaf PF15339.6 KUM62800.1 - 0.24 11.1 3.8 0.11 12.2 1.0 1.8 2 0 0 2 2 2 0 Acrosome formation-associated factor TFIIA PF03153.13 KUM62800.1 - 0.26 11.3 22.6 0.83 9.6 22.6 1.9 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cation_ATPase_C PF00689.21 KUM62801.1 - 1.8e-07 31.1 10.4 2.4e-07 30.6 10.4 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KUM62802.1 - 3.5e-16 60.1 0.0 1.9e-06 28.3 0.0 3.1 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KUM62802.1 - 1.2e-06 28.2 0.6 1.8e-06 27.6 0.6 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 KUM62802.1 - 0.00075 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Forkhead PF00250.18 KUM62803.1 - 1.6e-35 121.2 0.1 2.8e-35 120.4 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain G10 PF01125.17 KUM62804.1 - 2.5e-67 225.2 4.9 2.8e-67 225.0 4.9 1.0 1 0 0 1 1 1 1 G10 protein AA_kinase PF00696.28 KUM62805.1 - 6.3e-40 137.3 0.0 1.1e-39 136.5 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 KUM62805.1 - 5.8e-11 42.0 1.3 1.3e-08 34.5 0.1 2.4 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KUM62805.1 - 6.2e-09 35.5 1.3 2.4e-06 27.2 0.1 3.1 3 0 0 3 3 3 2 ACT domain zf-Tim10_DDP PF02953.15 KUM62806.1 - 1.2e-21 76.2 2.8 1.5e-21 75.8 2.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger AAA_18 PF13238.6 KUM62808.1 - 6.5e-26 91.4 0.2 1.6e-25 90.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KUM62808.1 - 1.9e-08 34.8 0.0 4.1e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KUM62808.1 - 0.00025 21.5 0.0 0.00043 20.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KUM62808.1 - 0.0016 18.9 0.0 0.005 17.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain ADK PF00406.22 KUM62808.1 - 0.003 17.7 0.1 0.023 14.8 0.1 2.1 1 1 1 2 2 2 1 Adenylate kinase RNA_helicase PF00910.22 KUM62808.1 - 0.0043 17.4 0.0 0.0078 16.6 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 KUM62808.1 - 0.0065 16.7 0.0 0.013 15.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KUM62808.1 - 0.012 15.6 0.2 0.029 14.3 0.1 1.7 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 KUM62808.1 - 0.012 15.8 0.0 0.034 14.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KUM62808.1 - 0.013 15.8 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KUM62808.1 - 0.02 14.9 0.0 0.044 13.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 KUM62808.1 - 0.046 14.0 0.0 0.09 13.1 0.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain KTI12 PF08433.10 KUM62808.1 - 0.063 12.7 0.0 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Cytidylate_kin2 PF13189.6 KUM62808.1 - 0.076 13.1 0.0 0.2 11.8 0.0 1.8 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_3 PF07726.11 KUM62808.1 - 0.08 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 KUM62808.1 - 0.083 12.7 0.2 9.9 6.0 0.1 2.3 1 1 0 2 2 2 0 Deoxynucleoside kinase Peptidase_C78 PF07910.13 KUM62809.1 - 2.8e-70 236.1 0.0 3.8e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf_UBZ PF18439.1 KUM62809.1 - 0.00035 20.1 0.2 0.00088 18.8 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KUM62809.1 - 0.014 15.7 3.6 2 8.7 0.6 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KUM62809.1 - 1.1 10.3 5.5 7.8 7.6 1.5 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4190 PF13828.6 KUM62810.1 - 6.5 6.6 11.7 10 6.0 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) zf-rbx1 PF12678.7 KUM62811.1 - 3.7e-25 88.0 12.8 5.3e-25 87.5 12.8 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KUM62811.1 - 1.9e-17 63.1 10.3 2.5e-17 62.7 10.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KUM62811.1 - 2.8e-06 27.6 14.8 9.9e-05 22.6 14.8 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KUM62811.1 - 9.9e-05 22.1 3.7 9.9e-05 22.1 3.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM62811.1 - 0.0014 18.4 11.9 0.026 14.4 11.9 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KUM62811.1 - 0.2 11.8 9.2 0.87 9.8 9.3 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 KUM62811.1 - 0.26 11.2 10.6 0.63 9.9 4.4 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KUM62811.1 - 0.43 10.6 7.8 1.6 8.8 7.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KUM62811.1 - 0.6 9.8 14.7 0.11 12.1 4.6 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KUM62811.1 - 1 9.1 17.1 95 2.9 17.1 2.5 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 KUM62811.1 - 8.5 6.4 11.4 48 4.0 11.4 2.3 1 1 0 1 1 1 0 zinc-RING finger domain PNRC PF15365.6 KUM62812.1 - 9.2e-09 34.9 7.7 9.2e-09 34.9 7.7 4.9 5 0 0 5 5 5 1 Proline-rich nuclear receptor coactivator motif GHMP_kinases_N PF00288.26 KUM62813.1 - 2e-10 40.8 0.0 4e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KUM62813.1 - 6.1e-06 26.5 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal SPC12 PF06645.13 KUM62814.1 - 1.6e-28 98.6 0.1 1.8e-28 98.4 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ZYG-11_interact PF05884.12 KUM62814.1 - 0.01 15.3 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF3040 PF11239.8 KUM62814.1 - 0.16 12.3 0.4 0.21 11.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) PDT PF00800.18 KUM62816.1 - 5e-63 212.2 0.0 6.7e-63 211.8 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KUM62816.1 - 2.7e-05 23.9 0.0 6.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 ACT domain DDOST_48kD PF03345.14 KUM62816.1 - 0.024 13.5 0.0 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta eRF1_2 PF03464.15 KUM62817.1 - 7.1e-45 152.6 0.0 1.2e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KUM62817.1 - 6e-38 129.8 0.7 1.1e-37 128.9 0.7 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KUM62817.1 - 7.3e-18 64.8 0.0 1.2e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KUM62817.1 - 1.2e-07 32.1 0.0 2.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KUM62817.1 - 2.5e-07 31.1 0.0 3.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Ribosomal_L7Ae PF01248.26 KUM62817.1 - 0.047 13.4 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Aa_trans PF01490.18 KUM62818.1 - 2.3e-66 224.2 29.8 2.7e-66 224.0 29.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MerC PF03203.14 KUM62818.1 - 0.0077 16.7 1.3 0.0077 16.7 1.3 3.7 3 1 1 4 4 4 1 MerC mercury resistance protein p450 PF00067.22 KUM62819.1 - 2e-37 129.0 0.0 2.5e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KUM62820.1 - 2.5e-08 33.1 0.0 2.9e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.17 KUM62822.1 - 2.5e-66 223.3 0.0 3.2e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Bmt2 PF11968.8 KUM62823.1 - 5.5e-94 314.1 0.0 6.7e-94 313.8 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KUM62823.1 - 0.044 13.6 0.0 0.079 12.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF4208 PF13907.6 KUM62823.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) Ribosomal_L23eN PF03939.13 KUM62824.1 - 2.7e-23 81.9 7.5 6.2e-23 80.8 7.5 1.7 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KUM62824.1 - 5e-15 55.6 1.4 1.1e-14 54.5 1.4 1.7 1 0 0 1 1 1 1 Ribosomal protein L23 HNOBA PF07701.14 KUM62824.1 - 0.046 13.2 0.2 0.093 12.2 0.2 1.5 1 1 0 1 1 1 0 Heme NO binding associated MaoC_dehydratas PF01575.19 KUM62825.1 - 0.00099 18.7 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain DER1 PF04511.15 KUM62826.1 - 3.4e-24 85.8 10.1 3.9e-24 85.6 10.1 1.0 1 0 0 1 1 1 1 Der1-like family DKCLD PF08068.12 KUM62827.1 - 1.7e-32 111.3 0.9 4.5e-31 106.7 0.2 2.8 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KUM62827.1 - 1.6e-22 79.4 0.2 3.1e-22 78.5 0.2 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 KUM62827.1 - 3.2e-22 79.5 1.4 3e-19 69.9 0.2 3.9 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 KUM62827.1 - 2.3e-21 75.6 1.3 4.5e-21 74.6 1.3 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KUM62827.1 - 0.0014 18.8 0.0 0.0035 17.6 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain TFIIF_alpha PF05793.12 KUM62827.1 - 0.37 9.3 21.6 0.5 8.9 21.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RR_TM4-6 PF06459.12 KUM62827.1 - 1.5 8.6 12.6 1.9 8.2 12.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 KUM62827.1 - 9.9 6.2 26.5 17 5.4 26.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SMI1_KNR4 PF09346.10 KUM62830.1 - 1.3e-32 113.0 0.0 3e-32 111.8 0.0 1.7 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Polysacc_synt PF01943.17 KUM62831.1 - 0.068 12.6 0.0 0.078 12.4 0.0 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein EamA PF00892.20 KUM62832.1 - 2.9e-05 24.2 6.4 2.9e-05 24.2 6.4 2.3 2 0 0 2 2 2 1 EamA-like transporter family DUF1077 PF06417.12 KUM62832.1 - 0.17 11.9 3.7 3.2 7.8 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) Thioredoxin PF00085.20 KUM62833.1 - 0.00072 19.5 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin CLTH PF10607.9 KUM62834.1 - 2.8e-37 127.9 2.2 5.5e-37 126.9 2.2 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain YhdB PF14148.6 KUM62834.1 - 0.0035 17.4 0.8 0.14 12.2 0.1 3.0 3 0 0 3 3 3 1 YhdB-like protein LisH PF08513.11 KUM62834.1 - 0.058 13.4 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 LisH DUF3673 PF12425.8 KUM62834.1 - 0.11 12.4 0.1 1 9.4 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3673) UL73_N PF12522.8 KUM62834.1 - 0.2 11.5 7.7 0.41 10.4 7.7 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal DUF2431 PF10354.9 KUM62835.1 - 2.7e-62 209.9 0.0 3.7e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Ribosomal_L19e PF01280.20 KUM62835.1 - 0.028 14.5 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein L19e Sigma70_ner PF04546.13 KUM62835.1 - 3.5 7.5 7.3 22 4.8 2.9 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region Myosin_head PF00063.21 KUM62836.1 - 7.8e-266 883.6 1.1 1.1e-265 883.1 1.1 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KUM62836.1 - 4.1e-26 91.3 2.1 4.1e-26 91.3 2.1 2.9 2 1 0 2 2 2 1 DIL domain IQ PF00612.27 KUM62836.1 - 3.2e-13 48.2 30.6 0.0003 20.3 0.5 6.7 6 0 0 6 6 6 4 IQ calmodulin-binding motif Myosin_N PF02736.19 KUM62836.1 - 1.3e-05 24.9 0.7 3.3e-05 23.6 0.7 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain GAS PF13851.6 KUM62836.1 - 8.8e-05 21.9 27.5 0.009 15.4 15.0 2.7 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding AAA_22 PF13401.6 KUM62836.1 - 0.00088 19.6 0.2 0.0057 16.9 0.1 2.5 2 1 0 2 2 1 1 AAA domain TMP_2 PF06791.13 KUM62836.1 - 0.0015 18.2 2.1 0.0032 17.1 2.1 1.5 1 0 0 1 1 1 1 Prophage tail length tape measure protein RsgA_GTPase PF03193.16 KUM62836.1 - 0.0029 17.5 0.0 0.0094 15.9 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KUM62836.1 - 0.0032 17.9 1.2 0.014 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Pox_A_type_inc PF04508.12 KUM62836.1 - 0.0054 16.5 0.3 0.0054 16.5 0.3 2.5 2 0 0 2 2 1 1 Viral A-type inclusion protein repeat Herpes_BLRF2 PF05812.12 KUM62836.1 - 0.028 14.5 5.9 0.14 12.3 5.9 2.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein T2SSE PF00437.20 KUM62836.1 - 0.034 13.2 0.0 0.08 12.0 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Baculo_PEP_C PF04513.12 KUM62836.1 - 0.058 13.4 7.4 0.087 12.9 4.6 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_helicase PF00910.22 KUM62836.1 - 0.16 12.4 0.0 0.64 10.4 0.0 2.1 1 0 0 1 1 1 0 RNA helicase Sec34 PF04136.15 KUM62836.1 - 0.17 11.7 6.8 0.61 10.0 6.3 2.3 1 1 0 1 1 1 0 Sec34-like family Tropomyosin_1 PF12718.7 KUM62836.1 - 0.64 10.2 27.1 5.9 7.0 16.3 2.8 1 1 1 2 2 2 0 Tropomyosin like FliJ PF02050.16 KUM62836.1 - 0.8 9.9 24.7 0.039 14.2 14.9 3.4 1 1 2 3 3 3 0 Flagellar FliJ protein ABC_tran PF00005.27 KUM62836.1 - 1.6 9.3 4.4 1.6 9.3 0.0 2.8 2 1 0 2 2 2 0 ABC transporter Phage_GP20 PF06810.11 KUM62836.1 - 1.8 8.4 16.3 3.6 7.4 2.2 2.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 FUSC PF04632.12 KUM62836.1 - 5.9 5.3 7.6 12 4.3 7.6 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3450 PF11932.8 KUM62836.1 - 7.9 5.7 30.2 0.16 11.2 12.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KUM62836.1 - 9.3 6.8 36.5 0.84 10.2 22.0 3.8 2 1 1 3 3 3 0 Apg6 coiled-coil region FlaC_arch PF05377.11 KUM62836.1 - 9.6 6.7 10.4 51 4.4 0.2 4.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Ham1p_like PF01725.16 KUM62837.1 - 3.9e-61 206.2 0.0 4.5e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Pkinase PF00069.25 KUM62838.1 - 2.2e-08 33.8 0.4 0.00019 20.9 0.1 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KUM62838.1 - 0.00019 20.8 0.1 0.0013 18.0 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase Bestrophin PF01062.21 KUM62839.1 - 1.1e-55 189.1 0.0 1.4e-55 188.8 0.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Arm PF00514.23 KUM62840.1 - 1.2e-75 247.5 28.0 2.9e-13 49.3 0.1 11.4 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KUM62840.1 - 2.4e-19 69.4 9.8 5e-05 23.7 0.1 8.2 8 1 1 9 9 8 5 HEAT-like repeat HEAT_2 PF13646.6 KUM62840.1 - 1.8e-17 63.5 7.2 6.6e-05 23.2 0.1 6.8 3 3 3 6 6 6 4 HEAT repeats HEAT PF02985.22 KUM62840.1 - 8.7e-17 59.8 12.6 0.31 11.4 0.0 9.1 10 0 0 10 10 9 5 HEAT repeat Adaptin_N PF01602.20 KUM62840.1 - 2.2e-12 46.4 6.5 6.1e-07 28.4 0.8 2.7 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 KUM62840.1 - 2.9e-12 46.6 5.2 8.8e-08 31.9 1.8 2.5 1 1 1 2 2 2 2 Armadillo-like KAP PF05804.12 KUM62840.1 - 2.3e-10 39.3 0.5 4.2e-10 38.4 0.5 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KUM62840.1 - 6.1e-10 38.9 0.5 2.7e-05 23.6 0.5 3.2 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 KUM62840.1 - 1.1e-05 25.5 6.3 0.052 13.6 0.1 5.1 2 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 KUM62840.1 - 4.5e-05 23.6 0.9 14 5.8 0.0 5.2 2 1 5 7 7 7 0 V-ATPase subunit H DUF3361 PF11841.8 KUM62840.1 - 5.9e-05 23.1 6.9 0.86 9.5 0.4 4.1 1 1 2 4 4 4 3 Domain of unknown function (DUF3361) DUF5578 PF17741.1 KUM62840.1 - 0.00048 19.6 6.8 2.8 7.3 0.0 5.1 2 1 4 6 6 6 1 Family of unknown function (DUF5578) Atx10homo_assoc PF09759.9 KUM62840.1 - 0.0025 17.8 6.5 1.1 9.3 0.4 4.9 3 2 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain IFRD PF05004.13 KUM62840.1 - 0.0037 16.4 6.3 1.4 8.0 0.3 4.5 3 2 1 4 4 4 2 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 KUM62840.1 - 0.011 16.3 0.0 3 8.5 0.0 3.6 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 KUM62840.1 - 0.021 15.4 5.7 27 5.8 0.3 6.1 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 KUM62840.1 - 0.033 14.2 1.9 1.7 8.6 0.5 3.3 2 2 1 3 3 3 0 Myosin-binding striated muscle assembly central GTP_EFTU PF00009.27 KUM62841.1 - 4.3e-58 196.1 0.0 7.1e-58 195.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KUM62841.1 - 2.4e-15 56.3 0.0 5.9e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KUM62841.1 - 9.6e-09 35.5 0.0 8.6e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KUM62841.1 - 1.6e-06 28.1 0.0 3.9e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KUM62841.1 - 0.0035 17.1 0.0 0.012 15.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KUM62841.1 - 0.075 13.1 0.0 0.21 11.7 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Atg14 PF10186.9 KUM62843.1 - 1.8e-13 50.3 0.3 1.8e-13 50.3 0.3 2.5 3 0 0 3 3 3 2 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KUM62843.1 - 3.1e-10 39.5 2.6 0.0027 16.7 0.1 3.2 3 0 0 3 3 3 3 Vacuolar protein sorting 38 APG6 PF04111.12 KUM62843.1 - 0.0039 17.2 0.0 0.0081 16.1 0.0 1.5 1 0 0 1 1 1 1 Apg6 BARA domain Spc7 PF08317.11 KUM62843.1 - 1.7 7.4 12.9 3 6.7 12.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Mhr1 PF12829.7 KUM62844.1 - 2.2e-29 101.3 0.3 5.9e-29 100.0 0.3 1.7 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination PP2C PF00481.21 KUM62845.1 - 3.3e-62 210.4 0.2 3.1e-50 171.2 0.2 3.1 1 1 1 2 2 2 2 Protein phosphatase 2C DUF4604 PF15377.6 KUM62846.1 - 2e-18 67.4 17.2 2.3e-18 67.2 17.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) F-box PF00646.33 KUM62847.1 - 0.011 15.5 0.2 0.027 14.3 0.2 1.7 1 0 0 1 1 1 0 F-box domain DUF2020 PF09449.10 KUM62848.1 - 0.11 12.3 0.3 0.69 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2020) Alb1 PF09135.11 KUM62849.1 - 1.4e-32 112.7 14.6 1.9e-32 112.3 14.6 1.2 1 0 0 1 1 1 1 Alb1 Dynamin_N PF00350.23 KUM62849.1 - 0.11 12.6 1.4 0.16 12.0 1.4 1.4 1 1 0 1 1 1 0 Dynamin family UCH PF00443.29 KUM62850.1 - 2.1e-31 109.4 0.0 5e-31 108.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KUM62850.1 - 1.2e-05 25.1 1.3 9.5e-05 22.1 1.3 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RING_UBOX PF13445.6 KUM62853.1 - 0.00027 20.9 3.5 0.00055 19.9 3.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KUM62853.1 - 0.00075 19.8 2.2 0.0014 18.9 2.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KUM62853.1 - 0.0049 16.7 1.6 0.011 15.6 1.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KUM62853.1 - 0.0052 16.7 5.9 0.0087 16.0 5.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain FYVE PF01363.21 KUM62853.1 - 0.0093 16.1 3.6 0.016 15.3 3.6 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-C3HC4_2 PF13923.6 KUM62853.1 - 0.014 15.3 3.3 0.044 13.6 3.3 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KUM62853.1 - 0.04 13.8 5.5 0.35 10.8 5.6 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KUM62853.1 - 0.11 12.4 7.6 0.38 10.7 7.6 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-dskA_traR PF01258.17 KUM62853.1 - 0.14 12.1 0.1 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger IBR PF01485.21 KUM62853.1 - 1.4 9.2 6.5 3 8.1 1.3 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FHA PF00498.26 KUM62854.1 - 8.8e-14 51.6 0.0 1.6e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KUM62854.1 - 2.4e-10 39.9 4.2 4.6e-10 39.1 4.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KUM62854.1 - 2.9e-07 30.7 8.3 5.9e-07 29.7 8.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KUM62854.1 - 0.00041 20.3 6.0 0.00077 19.4 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Yop-YscD_cpl PF16697.5 KUM62854.1 - 0.00052 20.3 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_2 PF13923.6 KUM62854.1 - 0.0081 16.0 8.8 0.016 15.0 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM62854.1 - 0.023 14.6 7.4 0.052 13.4 7.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KUM62854.1 - 0.046 13.8 2.8 0.095 12.8 2.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KUM62854.1 - 0.047 14.0 8.3 0.14 12.5 8.3 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING-like PF08746.11 KUM62854.1 - 0.05 13.9 4.8 0.12 12.8 4.8 1.7 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 KUM62854.1 - 0.14 12.1 5.6 0.29 11.0 5.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 KUM62854.1 - 0.63 10.2 6.9 1.5 9.1 6.4 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KUM62854.1 - 1.8 8.3 7.9 4.3 7.0 7.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type MDM10 PF12519.8 KUM62855.1 - 8.1e-84 282.1 0.2 6.4e-62 209.9 1.9 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 RL10P_insert PF17777.1 KUM62856.1 - 4.1e-21 74.7 0.0 6.7e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KUM62856.1 - 4.7e-19 68.4 0.0 9.8e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribonuc_L-PSP PF01042.21 KUM62856.1 - 0.14 12.2 0.0 0.46 10.5 0.0 1.9 2 0 0 2 2 2 0 Endoribonuclease L-PSP U1snRNP70_N PF12220.8 KUM62857.1 - 2e-25 89.3 2.0 3.7e-25 88.4 2.0 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KUM62857.1 - 1.5e-15 56.7 0.0 2.6e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KUM62857.1 - 0.00017 21.6 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif L51_S25_CI-B8 PF05047.16 KUM62858.1 - 1e-14 54.2 0.1 1.5e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Solute_trans_a PF03619.16 KUM62859.1 - 2e-58 198.0 14.3 2.4e-58 197.8 14.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Fic PF02661.18 KUM62860.1 - 0.00044 21.1 0.0 0.0019 19.1 0.0 2.0 2 0 0 2 2 2 1 Fic/DOC family Dynamin_N PF00350.23 KUM62861.1 - 4.4e-17 62.7 0.1 1.1e-16 61.4 0.1 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KUM62861.1 - 1.7e-10 41.0 0.1 3.2e-09 36.9 0.0 3.0 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KUM62861.1 - 9.6e-07 28.5 0.4 3.3e-05 23.5 0.3 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF2205 PF10224.9 KUM62861.1 - 0.025 14.6 0.3 0.073 13.1 0.3 1.8 1 0 0 1 1 1 0 Short coiled-coil protein AAA_18 PF13238.6 KUM62861.1 - 0.028 15.0 0.0 0.12 12.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain Exo_endo_phos_2 PF14529.6 KUM62861.1 - 0.036 13.9 0.0 0.095 12.5 0.0 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase IIGP PF05049.13 KUM62861.1 - 0.047 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) TsaE PF02367.17 KUM62861.1 - 0.052 13.6 0.0 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KUM62861.1 - 0.059 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain cobW PF02492.19 KUM62861.1 - 0.093 12.3 1.1 1.4 8.5 1.1 2.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KUM62861.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF883 PF05957.13 KUM62861.1 - 0.18 12.4 1.3 39 4.9 0.0 3.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) PTCB-BRCT PF12738.7 KUM62862.1 - 4.9e-52 173.7 0.7 8.1e-24 83.4 0.1 4.2 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 KUM62862.1 - 9.9e-32 109.2 0.6 4.1e-15 55.9 0.1 4.6 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KUM62862.1 - 5.1e-17 62.1 0.0 7.3e-06 26.3 0.0 4.4 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KUM62862.1 - 2.5e-08 34.1 3.9 0.0017 18.6 0.1 4.4 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KUM62862.1 - 0.0024 17.9 0.0 2 8.6 0.0 3.4 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.25 KUM62863.1 - 6.5e-71 238.8 0.0 7.4e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM62863.1 - 6e-34 117.5 0.0 7.6e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM62863.1 - 0.0024 17.3 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KUM62863.1 - 0.011 14.7 0.1 0.081 11.9 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 KUM62863.1 - 0.02 14.8 0.1 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KUM62863.1 - 0.045 13.1 0.2 0.13 11.6 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Snf7 PF03357.21 KUM62864.1 - 1.6e-34 119.0 21.1 3.5e-34 117.9 19.7 1.8 1 1 1 2 2 2 1 Snf7 RepB_primase PF16793.5 KUM62864.1 - 0.083 13.0 0.3 0.083 13.0 0.3 1.9 1 1 0 2 2 2 0 RepB DNA-primase from phage plasmid YlqD PF11068.8 KUM62864.1 - 3.5 8.0 18.2 29 5.0 11.0 2.2 1 1 1 2 2 2 0 YlqD protein TPR_MLP1_2 PF07926.12 KUM62864.1 - 7.6 6.6 12.6 15 5.6 8.2 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Pro_isomerase PF00160.21 KUM62866.1 - 1.3e-39 136.0 0.0 2.7e-39 135.0 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 KUM62866.1 - 0.00026 21.1 0.0 0.00065 19.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 KUM62866.1 - 0.0007 19.7 0.1 0.0052 16.9 0.0 2.4 1 1 1 2 2 2 1 U-box domain Rtf2 PF04641.12 KUM62866.1 - 0.0035 16.7 4.1 0.0073 15.7 0.2 2.9 2 1 0 2 2 2 1 Rtf2 RING-finger PIF1 PF05970.14 KUM62867.1 - 2.4e-65 221.1 0.0 5.2e-51 173.9 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KUM62867.1 - 4.8e-24 85.2 0.0 7.6e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KUM62867.1 - 8.2e-12 45.7 0.0 1.6e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KUM62867.1 - 4.9e-06 26.8 0.0 1.4e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KUM62867.1 - 6.5e-05 23.3 0.1 0.032 14.6 0.0 2.8 2 1 0 2 2 2 1 RNA helicase Herpes_Helicase PF02689.14 KUM62867.1 - 7.2e-05 20.9 0.0 0.00094 17.2 0.0 2.4 3 0 0 3 3 3 1 Helicase AAA_7 PF12775.7 KUM62867.1 - 0.0001 21.9 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KUM62867.1 - 0.00072 20.0 0.0 0.0021 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.6 KUM62867.1 - 0.0018 18.0 0.1 0.0058 16.4 0.1 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KUM62867.1 - 0.01 15.4 1.9 0.012 15.1 0.1 2.0 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain AAA PF00004.29 KUM62867.1 - 0.011 16.2 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KUM62867.1 - 0.018 14.2 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 KUM62867.1 - 0.019 14.2 0.0 0.055 12.7 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SH3_13 PF18335.1 KUM62867.1 - 0.024 14.5 0.1 0.07 13.0 0.1 1.8 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain PhoH PF02562.16 KUM62867.1 - 0.038 13.4 0.0 0.13 11.7 0.0 2.0 1 1 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 KUM62867.1 - 0.052 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 KUM62867.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF5605 PF18310.1 KUM62867.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) ResIII PF04851.15 KUM62867.1 - 0.077 13.0 0.3 0.26 11.3 0.3 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 KUM62867.1 - 0.078 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_11 PF13086.6 KUM62867.1 - 0.082 12.7 0.0 0.082 12.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 KUM62867.1 - 0.087 12.8 0.1 6.6 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Helicase_RecD PF05127.14 KUM62867.1 - 0.089 12.6 0.2 0.38 10.6 0.2 2.0 1 1 0 1 1 1 0 Helicase RsgA_GTPase PF03193.16 KUM62867.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 KUM62867.1 - 0.11 12.4 0.5 0.42 10.5 0.0 2.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KUM62867.1 - 0.12 12.8 0.3 0.71 10.4 0.1 2.6 3 1 0 3 3 2 0 ABC transporter YjeF_N PF03853.15 KUM62868.1 - 1.5e-43 148.6 0.2 2.3e-43 148.0 0.2 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KUM62868.1 - 6.6e-08 33.4 0.5 6.6e-08 33.4 0.5 2.2 2 0 0 2 2 2 1 FDF domain NTP_transferase PF00483.23 KUM62868.1 - 0.17 11.5 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase TIM PF00121.18 KUM62869.1 - 1.3e-91 306.3 1.1 1.5e-91 306.1 1.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 KUM62869.1 - 0.022 14.2 0.1 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 CutC family DeoRC PF00455.22 KUM62869.1 - 0.041 13.8 0.4 15 5.5 0.2 2.7 2 1 1 3 3 3 0 DeoR C terminal sensor domain DUF4376 PF14301.6 KUM62870.1 - 0.075 13.4 0.2 0.2 12.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) NUC129 PF08157.11 KUM62870.1 - 0.4 11.1 1.7 0.74 10.2 0.4 2.1 2 0 0 2 2 2 0 NUC129 domain NmrA PF05368.13 KUM62871.1 - 2.1e-12 47.1 0.0 2.6e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM62871.1 - 1.6e-06 28.1 0.0 2.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding EXOSC1 PF10447.9 KUM62872.1 - 6.5e-29 100.7 3.3 9.6e-29 100.2 3.3 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KUM62872.1 - 5.3e-11 42.1 0.3 1e-10 41.2 0.3 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region DUF5567 PF17722.1 KUM62872.1 - 0.074 12.9 0.9 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5567) Prp19 PF08606.11 KUM62873.1 - 3.4e-32 110.2 1.6 5.7e-32 109.5 1.6 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 KUM62873.1 - 2.9e-13 49.9 0.1 7.7e-07 29.3 0.0 4.2 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KUM62873.1 - 6.7e-13 48.9 3.4 0.00023 21.9 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat WD40_like PF17005.5 KUM62873.1 - 1.9e-08 34.0 0.1 5e-06 26.0 0.0 2.4 1 1 2 3 3 3 2 WD40-like domain Coatomer_WDAD PF04053.14 KUM62873.1 - 8.8e-08 31.6 0.6 0.0045 16.1 0.1 2.2 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.11 KUM62873.1 - 3.7e-05 23.7 0.1 0.0016 18.3 0.0 2.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A U-box PF04564.15 KUM62873.1 - 0.0043 17.2 0.0 0.0082 16.3 0.0 1.4 1 0 0 1 1 1 1 U-box domain Ge1_WD40 PF16529.5 KUM62873.1 - 0.0087 15.1 0.1 0.025 13.6 0.1 1.7 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein V_ATPase_I_N PF18670.1 KUM62873.1 - 0.02 15.3 0.2 0.062 13.7 0.2 1.9 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain Frtz PF11768.8 KUM62873.1 - 0.035 12.4 0.0 0.9 7.8 0.0 2.0 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF3450 PF11932.8 KUM62873.1 - 0.061 12.6 0.2 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-Nse PF11789.8 KUM62873.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cytochrom_D1 PF02239.16 KUM62873.1 - 0.081 11.4 1.2 1.9 7.0 0.3 2.4 1 1 2 3 3 3 0 Cytochrome D1 heme domain Vps16_N PF04841.13 KUM62874.1 - 1.5e-98 330.2 0.0 2.1e-98 329.8 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KUM62874.1 - 1.7e-87 293.5 0.0 3.2e-87 292.6 0.0 1.4 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 KUM62874.1 - 0.0029 17.9 0.0 0.35 11.2 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain CREPT PF16566.5 KUM62874.1 - 0.018 15.2 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour AAA_lid_2 PF17863.1 KUM62875.1 - 6.4e-08 32.3 0.0 1.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain PBP PF01161.20 KUM62877.1 - 5.4e-10 39.7 0.0 9.2e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_S26 PF10502.9 KUM62878.1 - 1.6e-06 28.0 0.0 0.00069 19.4 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 KUM62878.1 - 0.00011 22.1 0.1 0.00024 21.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase S24-like Sulfatase PF00884.23 KUM62879.1 - 4.1e-69 233.3 0.0 5.3e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 KUM62879.1 - 0.042 13.8 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF4976 PF16347.5 KUM62879.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4976) Fungal_trans_2 PF11951.8 KUM62880.1 - 2.4e-12 46.4 0.0 3.8e-12 45.7 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM62880.1 - 6.6e-10 38.9 8.0 1.2e-09 38.1 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH_2 PF16113.5 KUM62881.1 - 8.1e-129 429.9 0.0 1.1e-128 429.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KUM62881.1 - 2.7e-25 89.1 0.0 7.4e-25 87.7 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Ribosomal_L4 PF00573.22 KUM62882.1 - 3e-44 151.0 0.0 4.2e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DUF3990 PF13151.6 KUM62884.1 - 0.003 17.3 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) Peptidase_C48 PF02902.19 KUM62885.1 - 5.6e-13 49.2 0.0 3.4e-12 46.7 0.0 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4131 PF13567.6 KUM62886.1 - 0.025 14.2 1.2 1 9.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Cullin PF00888.22 KUM62887.1 - 9e-181 602.6 0.1 1.1e-180 602.3 0.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KUM62887.1 - 1.9e-24 85.5 0.4 6.9e-24 83.7 0.4 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain APH PF01636.23 KUM62888.1 - 6e-16 59.1 0.1 1.3e-15 58.0 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KUM62888.1 - 0.0016 17.9 0.0 0.07 12.5 0.0 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KUM62888.1 - 0.013 15.2 0.0 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 RIO1 family ADH_N PF08240.12 KUM62889.1 - 1.3e-27 95.8 0.2 2.4e-27 95.0 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM62889.1 - 2.8e-08 33.8 0.3 5.3e-08 32.9 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KUM62889.1 - 5.5e-06 26.2 0.2 1.1e-05 25.3 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 KUM62889.1 - 6.5e-05 22.5 0.0 0.00051 19.6 0.0 2.0 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 KUM62889.1 - 0.0039 16.0 0.4 0.012 14.3 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KUM62889.1 - 0.017 14.5 0.6 0.03 13.6 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KUM62889.1 - 0.047 13.3 0.2 0.095 12.3 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Methyltransf_25 PF13649.6 KUM62889.1 - 0.051 14.3 0.1 0.13 13.0 0.1 1.7 2 0 0 2 2 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KUM62889.1 - 0.058 13.0 0.1 0.093 12.3 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.24 KUM62889.1 - 0.079 12.0 1.6 0.14 11.2 0.7 1.7 1 1 1 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 KUM62889.1 - 0.12 11.6 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Ank PF00023.30 KUM62891.1 - 4.1e-09 36.5 0.0 6.8e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KUM62891.1 - 2.2e-08 34.6 0.0 2.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KUM62891.1 - 5.2e-08 33.0 0.0 9.4e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) F-box-like PF12937.7 KUM62891.1 - 4.4e-06 26.5 0.5 7.8e-06 25.7 0.5 1.5 1 0 0 1 1 1 1 F-box-like Ank_3 PF13606.6 KUM62891.1 - 4.8e-06 26.5 0.0 0.0055 17.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KUM62891.1 - 1.3e-05 25.6 0.0 0.0022 18.5 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) F-box_4 PF15966.5 KUM62891.1 - 0.0011 18.8 0.1 0.0015 18.4 0.1 1.2 1 0 0 1 1 1 1 F-box F-box PF00646.33 KUM62891.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 F-box domain Cu-oxidase_3 PF07732.15 KUM62892.1 - 6.5e-35 119.7 5.0 1.6e-34 118.5 5.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 KUM62892.1 - 6.7e-33 114.1 1.0 1.2e-32 113.3 0.3 1.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KUM62892.1 - 0.022 14.5 1.6 0.12 12.2 1.6 2.1 1 1 0 1 1 1 0 Multicopper oxidase DUF3433 PF11915.8 KUM62893.1 - 1.8e-32 111.7 15.7 8.4e-20 71.0 2.7 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) COX2_TM PF02790.15 KUM62893.1 - 0.052 13.7 4.3 0.69 10.1 2.9 2.7 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain ELM2 PF01448.24 KUM62893.1 - 0.14 12.9 0.0 0.46 11.3 0.0 1.9 1 1 0 1 1 1 0 ELM2 domain AP_endonuc_2 PF01261.24 KUM62894.1 - 1e-05 25.1 0.0 7.5e-05 22.3 0.0 2.3 1 1 0 2 2 2 1 Xylose isomerase-like TIM barrel DUF1264 PF06884.11 KUM62895.1 - 4.8e-78 260.6 0.0 5.9e-78 260.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) TPP_enzyme_N PF02776.18 KUM62896.1 - 4.1e-31 107.9 0.1 7e-31 107.1 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KUM62896.1 - 3.9e-14 52.7 0.0 1.3e-13 51.0 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KUM62896.1 - 2.3e-13 50.1 0.0 4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain NMT PF01233.19 KUM62896.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain MNHE PF01899.16 KUM62897.1 - 0.094 12.5 0.1 0.57 9.9 0.0 2.0 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit adh_short PF00106.25 KUM62898.1 - 1.5e-11 44.1 0.0 5.6e-06 26.0 0.0 2.9 2 1 0 2 2 2 2 short chain dehydrogenase NAD_kinase PF01513.21 KUM62899.1 - 2.9e-72 243.3 0.0 4.2e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase L_biotic_typeA PF04604.13 KUM62899.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Type-A lantibiotic Lactamase_B PF00753.27 KUM62900.1 - 2.3e-22 80.0 0.5 2.7e-21 76.5 0.5 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HAGH_C PF16123.5 KUM62900.1 - 2.6e-20 72.7 0.2 4.5e-20 71.9 0.2 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B_2 PF12706.7 KUM62900.1 - 0.00013 21.5 0.9 0.0011 18.5 0.7 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KUM62900.1 - 0.0018 18.2 0.2 0.0045 16.9 0.2 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.20 KUM62900.1 - 0.0082 15.7 0.1 0.052 13.0 0.0 1.9 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Las1 PF04031.13 KUM62901.1 - 3.8e-47 160.3 0.2 6.3e-47 159.5 0.1 1.4 2 0 0 2 2 2 1 Las1-like GATA PF00320.27 KUM62903.1 - 0.002 17.7 3.6 0.031 13.9 1.0 2.6 2 0 0 2 2 2 2 GATA zinc finger Rep_fac-A_3 PF08661.11 KUM62904.1 - 6.2e-24 84.4 0.0 7.2e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1 PF12658.7 KUM62904.1 - 0.041 13.8 0.1 0.56 10.2 0.1 2.1 1 1 0 1 1 1 0 Telomere capping, CST complex subunit MFAP1 PF06991.11 KUM62905.1 - 4.9e-70 235.8 31.6 4.9e-70 235.8 31.6 3.5 2 1 0 3 3 3 1 Microfibril-associated/Pre-mRNA processing DUF5494 PF17598.2 KUM62905.1 - 2.8 8.1 7.5 7.3 6.8 7.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5494) TRAPP PF04051.16 KUM62906.1 - 5.3e-40 136.5 0.0 7e-40 136.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Dak1 PF02733.17 KUM62907.1 - 9.3e-102 340.1 0.0 1.4e-101 339.5 0.0 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KUM62907.1 - 1.4e-44 152.1 0.8 1.4e-44 152.1 0.8 1.6 2 0 0 2 2 2 1 DAK2 domain Pox_P4B PF03292.14 KUM62907.1 - 0.18 10.1 0.0 0.27 9.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P4B major core protein LSM PF01423.22 KUM62908.1 - 6.6e-19 67.4 0.1 9e-19 66.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain APH PF01636.23 KUM62909.1 - 3.7e-05 23.8 0.0 0.00014 21.9 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family FPN1 PF06963.12 KUM62910.1 - 7.5e-140 466.3 23.2 8.7e-140 466.1 23.2 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Fungal_trans PF04082.18 KUM62912.1 - 8.6e-25 87.3 0.0 1.5e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM62912.1 - 2.9e-09 36.9 11.9 4.7e-09 36.2 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERG4_ERG24 PF01222.17 KUM62913.1 - 5.2e-156 519.7 4.9 6.2e-156 519.5 4.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KUM62913.1 - 2.1e-05 24.1 0.1 5.6e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Man-6-P_recep PF02157.15 KUM62914.1 - 1.4e-15 57.1 0.0 1.9e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 KUM62914.1 - 1.3e-11 44.8 0.0 3e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KUM62914.1 - 6.3e-08 32.8 0.1 0.00043 20.4 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Glyco_hydro_3_C PF01915.22 KUM62915.1 - 3.7e-52 177.3 0.0 5.5e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KUM62915.1 - 4.8e-39 134.6 0.0 3.4e-38 131.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KUM62915.1 - 1.1e-17 63.8 0.2 2.2e-17 62.9 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain ADH_zinc_N_2 PF13602.6 KUM62916.1 - 2.9e-16 60.7 0.2 4.9e-16 60.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KUM62916.1 - 4.3e-11 42.9 1.5 1e-10 41.7 1.2 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KUM62916.1 - 0.0001 21.9 0.6 0.00017 21.2 0.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.24 KUM62916.1 - 0.012 16.0 0.3 0.02 15.3 0.3 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ADH_N PF08240.12 KUM62916.1 - 0.014 15.3 0.0 0.037 13.9 0.0 1.8 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain RmlD_sub_bind PF04321.17 KUM62916.1 - 0.023 13.8 0.3 0.094 11.8 0.1 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.20 KUM62916.1 - 0.05 13.7 0.5 0.081 13.1 0.5 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Eno-Rase_NADH_b PF12242.8 KUM62916.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase EBP PF05241.12 KUM62917.1 - 0.0017 17.9 10.0 0.0089 15.5 10.0 2.1 1 1 0 1 1 1 1 Emopamil binding protein TraD_N PF12615.8 KUM62917.1 - 0.038 14.7 0.6 0.092 13.5 0.6 1.6 1 0 0 1 1 1 0 F sex factor protein N terminal Glyco_trans_4_5 PF16994.5 KUM62917.1 - 0.066 12.8 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-transferase family 4 bZIP_1 PF00170.21 KUM62918.1 - 0.0013 18.8 11.9 0.0023 18.0 10.5 2.0 1 1 1 2 2 2 1 bZIP transcription factor HAUS-augmin3 PF14932.6 KUM62918.1 - 0.44 10.1 7.0 0.62 9.6 7.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 A_deamin PF02137.18 KUM62919.1 - 3.2e-20 72.8 0.0 1.1e-18 67.8 0.0 2.6 2 1 0 2 2 2 2 Adenosine-deaminase (editase) domain HEAT PF02985.22 KUM62921.1 - 6.9e-39 128.5 10.9 0.015 15.5 0.1 13.2 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.6 KUM62921.1 - 8.6e-36 122.2 5.5 3.7e-11 43.3 0.0 7.7 4 2 4 8 8 8 7 HEAT repeats HEAT_EZ PF13513.6 KUM62921.1 - 7e-14 52.0 8.9 0.00097 19.6 0.0 9.0 6 3 4 10 10 10 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KUM62921.1 - 1.4e-11 44.9 3.0 0.0016 19.0 0.1 7.3 5 2 3 9 9 9 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KUM62921.1 - 6.8e-10 39.2 10.6 0.006 16.6 0.1 5.6 6 1 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KUM62921.1 - 3.5e-07 29.1 10.3 1.4e-05 23.8 3.4 4.5 3 1 1 4 4 4 3 Adaptin N terminal region RTP1_C1 PF10363.9 KUM62921.1 - 1e-06 28.9 6.0 0.23 11.7 0.2 5.0 4 1 1 5 5 5 3 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KUM62921.1 - 0.0011 18.6 2.1 0.3 10.6 0.1 4.3 3 2 2 5 5 5 1 CLASP N terminal Proteasom_PSMB PF10508.9 KUM62921.1 - 0.0065 15.0 3.8 0.48 8.9 0.0 2.6 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit Arm PF00514.23 KUM62921.1 - 0.0098 15.9 6.8 3.7 7.7 0.0 6.0 8 0 0 8 8 7 1 Armadillo/beta-catenin-like repeat TetR_C_16 PF17920.1 KUM62921.1 - 0.041 14.1 0.3 21 5.4 0.1 3.3 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain IFRD PF05004.13 KUM62921.1 - 0.14 11.2 0.5 3.2 6.8 0.0 3.2 2 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) API5 PF05918.11 KUM62921.1 - 0.77 8.5 4.6 0.47 9.2 0.3 2.9 2 1 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) Glyco_transf_90 PF05686.12 KUM62923.1 - 2.3e-19 69.6 10.0 1.8e-16 60.1 7.3 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 Abhydrolase_6 PF12697.7 KUM62924.1 - 5.6e-15 56.5 0.1 7.3e-14 52.9 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM62924.1 - 2.8e-11 43.5 0.0 8.1e-11 42.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM62924.1 - 3.1e-05 23.4 0.0 4.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Aldolase PF01081.19 KUM62924.1 - 0.12 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 KDPG and KHG aldolase EHN PF06441.12 KUM62924.1 - 0.13 12.6 0.3 0.27 11.6 0.3 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Myotub-related PF06602.14 KUM62925.1 - 1.3e-149 498.0 0.0 1.6e-149 497.6 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Ribosomal_S3_C PF00189.20 KUM62925.1 - 1.4e-23 83.2 0.1 3.9e-23 81.8 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KUM62925.1 - 5.3e-11 42.2 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 KH domain NAD_binding_1 PF00175.21 KUM62926.1 - 3.9e-06 27.5 0.0 5.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 KUM62926.1 - 0.00035 20.2 0.3 0.00043 19.9 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.22 KUM62927.1 - 2.7e-31 108.8 0.0 3e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FA_desaturase PF00487.24 KUM62928.1 - 2.6e-26 93.0 31.8 3.9e-26 92.4 31.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase GFA PF04828.14 KUM62929.1 - 1.4e-23 83.1 0.1 1.6e-23 82.9 0.1 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_transf_8 PF01501.20 KUM62930.1 - 1.3e-20 74.1 0.3 9e-20 71.3 0.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 KUM62930.1 - 0.00011 22.3 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Prok-E2_E PF14462.6 KUM62930.1 - 0.25 11.2 0.1 0.25 11.2 0.1 2.3 3 0 0 3 3 3 0 Prokaryotic E2 family E SLS PF14611.6 KUM62931.1 - 1.8e-33 116.2 0.0 2.8e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Glyco_hydro_53 PF07745.13 KUM62931.1 - 0.061 12.3 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 GST_C PF00043.25 KUM62932.1 - 1.4e-15 57.3 0.0 2.1e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KUM62932.1 - 1.2e-14 54.4 0.0 2.1e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KUM62932.1 - 4.6e-14 52.5 0.0 8.6e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KUM62932.1 - 2.7e-12 46.8 0.0 4.4e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KUM62932.1 - 8.7e-10 38.8 0.1 2.2e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KUM62932.1 - 9.4e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Plant_NMP1 PF06694.11 KUM62932.1 - 0.15 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) Phage_GP20 PF06810.11 KUM62933.1 - 0.028 14.2 7.3 0.035 13.9 7.3 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 UPF0242 PF06785.11 KUM62933.1 - 0.047 13.8 8.0 0.057 13.5 8.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HCMV_UL139 PF12507.8 KUM62933.1 - 0.051 14.0 2.5 0.065 13.6 2.5 1.2 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein DUF3450 PF11932.8 KUM62933.1 - 0.053 12.8 6.5 0.067 12.5 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PRKCSH-like PF12999.7 KUM62933.1 - 0.11 12.3 1.2 0.14 11.9 1.2 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like ERM PF00769.19 KUM62933.1 - 0.12 12.2 12.9 0.17 11.7 12.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Spc7 PF08317.11 KUM62933.1 - 0.12 11.2 9.4 0.15 10.9 9.4 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein CdvA PF18822.1 KUM62933.1 - 0.16 11.8 10.1 0.22 11.3 10.1 1.2 1 0 0 1 1 1 0 CdvA-like coiled-coil domain NinG PF05766.12 KUM62933.1 - 0.24 11.3 5.7 0.28 11.1 5.7 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein LsmAD PF06741.13 KUM62933.1 - 0.5 10.9 6.0 0.76 10.4 6.0 1.3 1 0 0 1 1 1 0 LsmAD domain DUF2951 PF11166.8 KUM62933.1 - 0.84 9.9 5.9 1.1 9.5 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Agouti PF05039.12 KUM62933.1 - 1.7 9.4 4.2 2.7 8.8 4.2 1.5 1 1 0 1 1 1 0 Agouti protein TMPIT PF07851.13 KUM62933.1 - 3.2 6.9 7.7 3.7 6.7 7.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein NT-C2 PF10358.9 KUM62934.1 - 9.3e-33 113.0 0.1 1.4e-32 112.4 0.1 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SF3b10 PF07189.11 KUM62937.1 - 6.2e-35 119.2 0.0 6.9e-35 119.0 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF3074 PF11274.8 KUM62938.1 - 7.6e-56 189.0 0.3 2.1e-55 187.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) START PF01852.19 KUM62938.1 - 0.015 14.7 0.2 2.9 7.2 0.0 2.9 3 0 0 3 3 3 0 START domain TSC22 PF01166.18 KUM62938.1 - 0.098 13.0 1.9 0.49 10.8 1.9 2.3 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF5342 PF17277.2 KUM62938.1 - 0.22 11.9 0.9 2.4 8.6 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5342) DUF3450 PF11932.8 KUM62938.1 - 0.93 8.7 20.3 0.026 13.8 10.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Filament PF00038.21 KUM62938.1 - 0.97 8.9 16.5 0.49 9.9 9.0 2.3 2 0 0 2 2 2 0 Intermediate filament protein DivIC PF04977.15 KUM62938.1 - 1.1 9.0 10.3 0.11 12.3 2.4 2.9 2 0 0 2 2 2 0 Septum formation initiator HALZ PF02183.18 KUM62938.1 - 1.2 9.5 9.0 0.43 10.8 2.7 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper FapA PF03961.13 KUM62938.1 - 1.5 7.3 13.5 0.24 10.0 7.6 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF1640 PF07798.11 KUM62938.1 - 8.8 6.3 13.4 1.3 9.0 7.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) GST_C_2 PF13410.6 KUM62939.1 - 1.7e-09 37.6 0.0 2.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KUM62939.1 - 0.0031 17.7 0.0 0.0052 17.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KUM62939.1 - 0.036 14.4 0.0 0.065 13.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Med29 PF11568.8 KUM62939.1 - 0.089 13.0 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 29 CorA PF01544.18 KUM62939.1 - 0.12 11.6 0.0 5.3 6.3 0.0 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein ADH_zinc_N PF00107.26 KUM62940.1 - 1.2e-25 90.0 0.2 2e-25 89.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM62940.1 - 7.6e-18 65.8 0.0 1.4e-17 65.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM62940.1 - 5.3e-09 35.9 0.0 2.1e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KUM62940.1 - 0.002 18.4 0.0 0.004 17.4 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain F-box PF00646.33 KUM62942.1 - 0.012 15.5 0.2 0.044 13.7 0.2 2.0 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KUM62942.1 - 0.014 15.3 0.1 0.036 14.0 0.1 1.7 1 0 0 1 1 1 0 F-box-like ABC_tran PF00005.27 KUM62943.1 - 5e-17 62.7 0.0 1.1e-16 61.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KUM62943.1 - 0.0054 17.0 0.2 0.06 13.6 0.2 2.3 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KUM62943.1 - 0.0067 15.5 0.2 0.01 14.9 0.2 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein SMC_N PF02463.19 KUM62943.1 - 0.011 15.2 0.2 0.76 9.2 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KUM62943.1 - 0.028 14.8 0.0 0.052 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KUM62943.1 - 0.037 13.4 0.2 0.074 12.4 0.2 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KUM62943.1 - 0.089 13.2 0.0 0.55 10.6 0.0 2.2 2 1 0 2 2 2 0 RNA helicase AAA_21 PF13304.6 KUM62943.1 - 0.092 12.5 0.1 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KUM62943.1 - 0.11 12.3 0.2 0.23 11.2 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KUM62943.1 - 0.15 12.5 0.1 1.6 9.2 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KUM62943.1 - 0.19 11.8 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 KUM62943.1 - 0.22 11.1 0.1 0.22 11.1 0.1 1.6 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KUM62943.1 - 0.24 11.1 0.1 0.35 10.6 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ABC_membrane PF00664.23 KUM62944.1 - 1.8e-22 80.3 4.2 2.7e-22 79.7 4.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KUM62944.1 - 2e-15 57.5 0.0 3.5e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KUM62944.1 - 0.0006 19.5 0.1 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 KUM62944.1 - 0.00073 19.7 0.2 0.0012 19.0 0.2 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain DUF815 PF05673.13 KUM62944.1 - 0.034 13.3 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 KUM62944.1 - 0.035 14.2 0.1 0.068 13.3 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KUM62944.1 - 0.049 13.5 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KUM62944.1 - 0.068 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 KUM62944.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KUM62944.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_21 PF13304.6 KUM62944.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KUM62944.1 - 0.11 13.0 0.1 0.18 12.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KUM62944.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 KUM62944.1 - 0.21 11.6 0.3 0.4 10.7 0.3 1.4 1 0 0 1 1 1 0 Dynamin family CotE PF10628.9 KUM62946.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) DAO PF01266.24 KUM62947.1 - 1.6e-25 90.5 0.3 2e-25 90.1 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KUM62947.1 - 0.0021 18.6 1.2 0.008 16.7 1.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM62947.1 - 0.0087 15.3 0.1 0.021 14.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KUM62947.1 - 0.031 13.5 0.3 0.097 11.9 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 KUM62947.1 - 0.12 11.6 0.2 0.2 10.8 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KUM62947.1 - 0.14 12.0 0.6 0.25 11.2 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain BNR_6 PF15899.5 KUM62949.1 - 0.00021 21.0 1.0 0.0012 18.8 0.2 2.6 2 0 0 2 2 2 1 BNR-Asp box repeat BNR_2 PF13088.6 KUM62949.1 - 0.00024 20.5 0.0 0.00063 19.1 0.0 1.7 1 0 0 1 1 1 1 BNR repeat-like domain Sortilin-Vps10 PF15902.5 KUM62949.1 - 0.008 15.0 0.1 0.7 8.6 0.0 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, BNR PF02012.20 KUM62949.1 - 0.014 15.3 4.2 0.75 10.0 0.2 3.4 3 0 0 3 3 3 0 BNR/Asp-box repeat DUF2433 PF10360.9 KUM62950.1 - 4.9e-47 159.1 0.0 8.1e-47 158.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.7 KUM62950.1 - 0.00071 19.8 0.0 0.0026 17.9 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KUM62950.1 - 0.00094 19.7 0.0 0.0025 18.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Aldo_ket_red PF00248.21 KUM62951.1 - 2.6e-41 141.7 0.0 7.1e-41 140.3 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Pro-kuma_activ PF09286.11 KUM62952.1 - 1.2e-46 158.5 0.1 2.4e-46 157.6 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KUM62952.1 - 1.6e-05 24.3 0.7 2.8e-05 23.5 0.7 1.3 1 0 0 1 1 1 1 Subtilase family Response_reg PF00072.24 KUM62953.1 - 1.8e-25 89.3 1.1 4.1e-25 88.1 0.4 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 KUM62953.1 - 2e-24 86.2 0.0 4.4e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KUM62953.1 - 4.1e-16 58.8 0.1 8.2e-16 57.8 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KUM62953.1 - 1.4e-12 47.7 0.0 3.6e-10 40.0 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KUM62953.1 - 1.1e-11 44.7 0.0 1.9e-07 31.0 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 KUM62953.1 - 1.6e-10 41.2 0.0 0.00011 22.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold DAO PF01266.24 KUM62954.1 - 8.1e-28 98.0 0.4 1.2e-27 97.4 0.4 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 KUM62954.1 - 0.0046 16.6 0.4 0.011 15.3 0.4 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF604 PF04646.12 KUM62954.1 - 0.0047 16.4 0.1 0.0076 15.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Pyr_redox_2 PF07992.14 KUM62954.1 - 0.0056 15.9 0.1 0.013 14.7 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KUM62954.1 - 0.037 13.1 0.2 0.062 12.4 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KUM62954.1 - 0.059 13.6 0.2 0.17 12.2 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 KUM62954.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 ThiF family Sacchrp_dh_NADP PF03435.18 KUM62954.1 - 0.14 12.5 0.0 0.91 9.8 0.1 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Fungal_trans_2 PF11951.8 KUM62956.1 - 6e-07 28.6 2.3 7.3e-07 28.3 2.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM62957.1 - 0.0031 17.6 4.9 0.0048 17.0 4.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Recep_L_domain PF01030.24 KUM62958.1 - 1.2e-06 28.6 0.3 0.00063 19.8 0.3 3.0 1 1 0 1 1 1 1 Receptor L domain Ecm33 PF12454.8 KUM62958.1 - 0.00031 20.8 0.7 0.00031 20.8 0.7 2.2 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein VSP PF03302.13 KUM62958.1 - 0.0029 16.5 0.4 0.0029 16.5 0.4 1.5 2 0 0 2 2 2 1 Giardia variant-specific surface protein SKG6 PF08693.10 KUM62958.1 - 0.0047 16.3 1.1 0.0047 16.3 1.1 2.3 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF347 PF03988.12 KUM62958.1 - 0.034 14.3 2.4 0.58 10.4 0.4 2.6 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) DUF4381 PF14316.6 KUM62958.1 - 0.056 13.7 0.4 0.12 12.7 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 KUM62958.1 - 0.07 14.0 0.0 0.16 12.8 0.0 1.6 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain MHYT PF03707.16 KUM62958.1 - 0.075 13.2 1.7 0.16 12.2 0.3 2.1 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat DUF4307 PF14155.6 KUM62958.1 - 0.16 11.8 0.4 0.75 9.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) Syndecan PF01034.20 KUM62958.1 - 0.18 11.7 0.3 0.37 10.8 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain CcmD PF04995.14 KUM62958.1 - 1.9 8.6 8.9 0.36 10.9 4.3 2.0 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Lipase_GDSL_2 PF13472.6 KUM62959.1 - 9.8e-13 48.9 1.7 1.2e-12 48.6 1.7 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KUM62959.1 - 1.1e-05 25.5 0.2 1.7e-05 24.9 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Amidase PF01425.21 KUM62960.1 - 7.7e-88 295.4 0.0 1e-87 295.0 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF2007 PF09413.10 KUM62960.1 - 0.068 13.3 0.0 1.1 9.4 0.1 2.4 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein PEX11 PF05648.14 KUM62961.1 - 2.9e-37 128.3 0.1 3.4e-37 128.1 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) F-actin_cap_A PF01267.17 KUM62962.1 - 6.3e-94 314.3 0.0 7.1e-94 314.2 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Med7 PF05983.11 KUM62963.1 - 1.8e-62 210.8 6.0 2.4e-62 210.4 6.0 1.2 1 0 0 1 1 1 1 MED7 protein Glyco_hydro_61 PF03443.14 KUM62963.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 DUF1213 PF06740.12 KUM62963.1 - 6.5 7.4 6.7 21 5.8 0.5 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1213) Fungal_trans PF04082.18 KUM62964.1 - 1.7e-10 40.4 0.1 3.7e-10 39.3 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KUM62964.1 - 0.0088 14.9 0.5 0.046 12.5 0.5 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain tRNA-synt_2c PF01411.19 KUM62965.1 - 5.4e-11 41.7 0.1 7.3e-11 41.3 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KUM62965.1 - 7.9e-06 25.9 0.2 1.6e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain PAP2 PF01569.21 KUM62966.1 - 3.8e-28 98.0 0.8 3.8e-28 98.0 0.8 1.9 2 1 0 2 2 2 1 PAP2 superfamily DUF2933 PF11666.8 KUM62966.1 - 0.049 13.7 0.4 0.049 13.7 0.4 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2933) RseC_MucC PF04246.12 KUM62966.1 - 2.1 8.3 6.7 6.8 6.7 0.5 3.0 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC PAP2_3 PF14378.6 KUM62966.1 - 5.2 6.7 13.1 2.3 7.9 8.6 2.5 1 1 1 2 2 2 0 PAP2 superfamily Cu_amine_oxid PF01179.20 KUM62968.1 - 1.2e-158 528.4 0.0 1.5e-158 528.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KUM62968.1 - 9.1e-07 29.0 0.1 1.7e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KUM62968.1 - 0.0057 17.0 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Fungal_trans_2 PF11951.8 KUM62970.1 - 4e-73 246.4 0.8 4.8e-73 246.2 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain ParA PF10609.9 KUM62971.1 - 2.6e-53 181.0 0.0 4.1e-53 180.4 0.0 1.4 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KUM62971.1 - 0.19 11.8 0.0 0.57 10.2 0.0 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain TRAUB PF08164.12 KUM62973.1 - 3.3e-29 101.2 0.1 3.3e-29 101.2 0.1 3.0 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KUM62973.1 - 1.2e-25 90.8 1.0 1.2e-25 90.8 1.0 2.9 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor ParA PF10609.9 KUM62974.1 - 1.8e-17 63.6 2.2 6.3e-17 61.8 2.2 1.7 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KUM62974.1 - 0.00038 20.5 2.0 0.0062 16.6 2.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KUM62974.1 - 0.0015 18.5 2.1 0.0064 16.4 2.1 1.8 1 1 0 1 1 1 1 AAA domain MutL PF13941.6 KUM62974.1 - 0.043 12.4 0.0 0.052 12.2 0.0 1.0 1 0 0 1 1 1 0 MutL protein MipZ PF09140.11 KUM62974.1 - 0.13 11.5 0.5 0.23 10.7 0.5 1.4 1 1 0 1 1 1 0 ATPase MipZ GFO_IDH_MocA PF01408.22 KUM62976.1 - 1.1e-21 77.9 0.1 1.8e-21 77.2 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KUM62976.1 - 3.9e-06 26.9 0.0 7.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DapB_N PF01113.20 KUM62976.1 - 0.004 17.3 0.0 0.066 13.3 0.0 2.4 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DUF4965 PF16335.5 KUM62977.1 - 2.1e-69 232.6 0.1 3e-69 232.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KUM62977.1 - 2.2e-59 201.0 0.0 3.2e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KUM62977.1 - 2.4e-48 164.7 0.1 4.4e-48 163.9 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KUM62977.1 - 0.00023 20.7 0.0 0.00047 19.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 KUM62977.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term PAP1 PF08601.10 KUM62978.1 - 2.3e-127 425.8 39.4 2.4e-125 419.1 20.6 4.0 2 1 1 3 3 3 2 Transcription factor PAP1 bZIP_1 PF00170.21 KUM62978.1 - 8.6e-08 32.2 9.6 1.7e-07 31.2 9.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor ERM PF00769.19 KUM62978.1 - 0.00072 19.4 2.3 0.0016 18.3 2.3 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family MbeD_MobD PF04899.12 KUM62978.1 - 0.0014 18.7 1.9 0.0028 17.7 1.9 1.5 1 0 0 1 1 1 1 MbeD/MobD like SHE3 PF17078.5 KUM62978.1 - 0.012 15.4 2.8 0.022 14.5 2.8 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 KUM62978.1 - 0.026 15.0 9.4 0.052 14.1 9.4 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor HAUS-augmin3 PF14932.6 KUM62978.1 - 0.099 12.2 2.8 0.17 11.4 2.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 bZIP_2 PF07716.15 KUM62978.1 - 0.38 10.9 12.5 1.8 8.7 12.5 2.0 1 1 0 1 1 1 0 Basic region leucine zipper TolA_bind_tri PF16331.5 KUM62978.1 - 0.55 10.4 5.1 0.65 10.1 2.9 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation Macoilin PF09726.9 KUM62978.1 - 6.9 5.1 12.6 1.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Macoilin family Tudor_3 PF18115.1 KUM62979.1 - 1.7e-07 31.0 0.0 3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KUM62979.1 - 0.0085 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) FlxA PF14282.6 KUM62979.1 - 0.029 14.3 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 FlxA-like protein Tudor_2 PF18104.1 KUM62979.1 - 0.16 11.7 0.0 0.41 10.4 0.0 1.7 1 1 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain NPC1_N PF16414.5 KUM62980.1 - 3.5e-84 282.2 6.6 4.9e-84 281.7 6.6 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KUM62980.1 - 5e-78 263.1 5.7 3.8e-50 170.8 0.0 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 KUM62980.1 - 9.6e-52 174.9 8.0 9.6e-52 174.9 8.0 3.5 3 1 0 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KUM62980.1 - 3e-06 26.4 8.6 3e-06 26.4 8.6 3.8 4 1 0 4 4 4 1 MMPL family Folate_rec PF03024.14 KUM62980.1 - 0.0021 18.0 2.3 0.0041 17.0 2.3 1.4 1 0 0 1 1 1 1 Folate receptor family HEAT PF02985.22 KUM62981.1 - 1.1e-17 62.6 1.8 0.00018 21.5 0.1 8.6 9 0 0 9 9 6 3 HEAT repeat HEAT_2 PF13646.6 KUM62981.1 - 8.5e-17 61.3 4.4 2.5e-06 27.8 0.0 7.5 6 3 4 10 10 9 5 HEAT repeats HEAT_EZ PF13513.6 KUM62981.1 - 1.2e-16 60.8 9.5 2.2e-06 28.0 0.0 8.6 8 1 0 8 8 8 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KUM62981.1 - 1.7e-11 44.5 0.4 0.056 14.0 0.0 6.5 5 1 1 6 6 6 3 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KUM62981.1 - 4.5e-10 39.1 4.4 6.6e-05 22.2 0.4 3.9 3 1 1 4 4 4 3 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 KUM62981.1 - 8.5e-10 38.9 4.8 0.036 14.1 0.0 4.5 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 KUM62981.1 - 1.3e-09 37.9 3.6 2.5e-08 33.7 0.3 3.2 3 0 0 3 3 2 1 Importin-beta N-terminal domain MMS19_C PF12460.8 KUM62981.1 - 1.9e-08 33.9 1.2 0.0014 17.9 0.0 3.5 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KUM62981.1 - 1.2e-06 28.2 0.0 0.0028 17.2 0.0 3.5 3 0 0 3 3 3 2 CLASP N terminal Adaptin_N PF01602.20 KUM62981.1 - 2.5e-05 23.0 0.4 0.37 9.3 0.0 4.2 3 3 0 3 3 3 2 Adaptin N terminal region Arm PF00514.23 KUM62981.1 - 2.9e-05 23.9 2.3 0.97 9.6 0.0 6.0 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KUM62981.1 - 9.1e-05 22.6 1.5 3 8.1 0.0 4.9 3 2 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 UME PF08064.13 KUM62981.1 - 0.00012 21.9 0.3 0.58 10.1 0.1 4.9 4 3 1 5 5 5 1 UME (NUC010) domain ParcG PF10274.9 KUM62981.1 - 0.0033 17.6 1.6 0.86 9.7 0.2 3.5 3 1 1 4 4 4 1 Parkin co-regulated protein V-ATPase_H_C PF11698.8 KUM62981.1 - 0.0063 16.6 0.7 17 5.6 0.1 4.3 4 0 0 4 4 4 0 V-ATPase subunit H UNC45-central PF11701.8 KUM62981.1 - 0.019 14.9 0.3 3.2 7.7 0.1 4.2 4 1 1 5 5 5 0 Myosin-binding striated muscle assembly central RIX1 PF08167.12 KUM62981.1 - 0.03 14.0 0.3 2 8.1 0.0 3.1 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis NUC173 PF08161.12 KUM62981.1 - 0.034 13.8 0.0 29 4.3 0.0 5.2 6 1 1 7 7 7 0 NUC173 domain DUF1804 PF08822.11 KUM62981.1 - 0.64 10.0 3.9 7 6.6 0.0 3.8 5 0 0 5 5 4 0 Protein of unknown function (DUF1804) Tyrosinase PF00264.20 KUM62982.1 - 1.1e-49 169.8 7.1 2.3e-49 168.7 7.1 1.6 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KUM62982.1 - 2e-14 54.3 0.0 3.5e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain Gal-bind_lectin PF00337.22 KUM62982.1 - 1.4e-09 37.6 0.0 3.6e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Galactoside-binding lectin Amidohydro_1 PF01979.20 KUM62983.1 - 3e-60 204.4 0.0 4.3e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KUM62983.1 - 6.8e-10 39.0 0.0 7.5e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KUM62983.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Adenosine/AMP deaminase OPT PF03169.15 KUM62984.1 - 8.6e-164 546.5 57.3 9.7e-164 546.4 57.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3937 PF13073.6 KUM62984.1 - 0.058 13.5 3.8 3.3 7.9 1.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3937) 2-Hacid_dh_C PF02826.19 KUM62985.1 - 1.2e-45 155.1 0.0 1.8e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KUM62985.1 - 3.9e-07 29.8 0.0 5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KUM62985.1 - 0.0084 16.3 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Acetyltransf_10 PF13673.7 KUM62986.1 - 1.6e-06 28.1 0.0 3.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KUM62986.1 - 3.9e-06 27.2 0.0 8.3e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM62986.1 - 9.3e-05 22.6 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KUM62986.1 - 0.00086 19.4 0.0 0.0045 17.1 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain EFhand_Ca_insen PF08726.10 KUM62986.1 - 0.0058 16.7 0.0 0.02 14.9 0.0 1.9 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Acetyltransf_CG PF14542.6 KUM62986.1 - 0.018 15.2 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SET PF00856.28 KUM62988.1 - 0.061 13.7 0.0 0.081 13.3 0.0 1.3 1 0 0 1 1 1 0 SET domain Glyco_hydro_25 PF01183.20 KUM62989.1 - 1.7e-39 135.9 0.1 1.9e-39 135.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Fungal_trans PF04082.18 KUM62990.1 - 5.7e-20 71.5 0.0 1.2e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM62990.1 - 1.1e-09 38.2 9.5 1.7e-09 37.7 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_fiss_reg PF05308.11 KUM62990.1 - 9.7 6.2 8.9 21 5.1 5.3 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator p450 PF00067.22 KUM62991.1 - 3.1e-35 121.8 0.0 3.8e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KUM62993.1 - 2.3e-63 214.6 0.0 2.6e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Longin_2 PF18639.1 KUM62994.1 - 0.41 10.5 2.3 0.44 10.4 0.2 1.8 2 0 0 2 2 2 0 Yeast longin domain DUF2678 PF10856.8 KUM62994.1 - 1.9 8.4 8.1 0.54 10.2 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2678) DUF4131 PF13567.6 KUM62994.1 - 5.2 6.7 10.4 1.1 8.9 2.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) LDB19 PF13002.7 KUM62995.1 - 6.7e-58 195.6 0.0 1e-57 195.0 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 KUM62995.1 - 1.5e-07 31.6 0.0 4.5e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain PIG-L PF02585.17 KUM62996.1 - 1.1e-29 103.7 0.0 2.3e-29 102.7 0.0 1.5 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase Thioredoxin_7 PF13899.6 KUM62997.1 - 2e-17 63.2 0.0 4.2e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KUM62997.1 - 1.9e-13 50.0 0.0 4.1e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KUM62997.1 - 6.1e-09 36.0 0.0 3.7e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 UBX domain Thioredoxin_2 PF13098.6 KUM62997.1 - 0.021 15.2 0.0 0.046 14.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredox_DsbH PF03190.15 KUM62997.1 - 0.076 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 AAA PF00004.29 KUM62998.1 - 4.1e-11 43.4 0.0 2.5e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KUM62998.1 - 3.4e-09 37.3 0.0 9.9e-09 35.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KUM62998.1 - 1.3e-08 35.2 0.0 3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 KUM62998.1 - 8.5e-08 32.1 0.0 3.5e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 KUM62998.1 - 8.5e-05 22.6 0.5 0.00018 21.6 0.0 1.8 2 0 0 2 2 1 1 AAA lid domain NTPase_1 PF03266.15 KUM62998.1 - 0.00041 20.3 0.0 0.00071 19.5 0.0 1.4 1 0 0 1 1 1 1 NTPase KTI12 PF08433.10 KUM62998.1 - 0.0013 18.3 0.2 0.63 9.4 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_7 PF12775.7 KUM62998.1 - 0.0021 17.6 0.0 0.0047 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Rad17 PF03215.15 KUM62998.1 - 0.0088 16.0 0.0 0.031 14.2 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain PIF1 PF05970.14 KUM62998.1 - 0.011 15.0 0.0 0.028 13.6 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase ATPase_2 PF01637.18 KUM62998.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 KUM62998.1 - 0.017 14.3 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 KUM62998.1 - 0.029 14.7 0.0 0.069 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KUM62998.1 - 0.032 14.8 0.0 0.23 12.0 0.0 2.3 2 0 0 2 2 2 0 ABC transporter DUF815 PF05673.13 KUM62998.1 - 0.075 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 KUM62998.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KUM62998.1 - 0.13 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_5 PF07728.14 KUM62998.1 - 0.13 12.3 0.0 0.31 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.27 KUM62999.1 - 2.5e-18 66.3 0.0 4.6e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KUM62999.1 - 1.4e-06 28.6 1.8 4.6e-06 26.9 1.8 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KUM62999.1 - 2.7e-05 24.4 0.0 6.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.9 KUM62999.1 - 0.019 14.7 0.6 1.1 9.0 0.1 3.0 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KUM62999.1 - 0.039 14.1 0.3 0.17 12.0 0.3 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP13 PF12921.7 KUM63001.1 - 4.8e-24 84.4 0.1 2.5e-23 82.1 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial ATPase expression PPR_3 PF13812.6 KUM63001.1 - 2.7e-07 30.6 0.0 0.0028 17.7 0.0 2.7 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 KUM63001.1 - 0.0053 16.9 0.0 15 5.9 0.0 3.8 3 0 0 3 3 3 2 PPR repeat family LSM PF01423.22 KUM63002.1 - 9.7e-16 57.2 0.3 1.3e-15 56.8 0.3 1.2 1 0 0 1 1 1 1 LSM domain AalphaY_MDB PF04611.12 KUM63002.1 - 0.18 11.8 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region Pkinase PF00069.25 KUM63003.1 - 3.6e-47 160.9 0.0 5.4e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM63003.1 - 2.1e-32 112.4 0.0 4.8e-32 111.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KUM63003.1 - 9.5e-05 21.3 0.0 0.00017 20.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KUM63003.1 - 0.00013 21.4 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PARM PF17061.5 KUM63003.1 - 3.7 7.6 13.9 6 6.9 13.9 1.3 1 0 0 1 1 1 0 PARM DUF1479 PF07350.12 KUM63005.1 - 0.037 12.8 0.0 1.5 7.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1479) F-box-like PF12937.7 KUM63008.1 - 1.9e-05 24.4 1.0 3.6e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 F-box-like PalH PF08733.10 KUM63009.1 - 5.9e-113 377.2 0.0 7.1e-113 376.9 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 Asp PF00026.23 KUM63010.1 - 3.5e-71 240.2 4.2 4.4e-71 239.9 4.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KUM63010.1 - 1.1e-05 25.8 3.3 0.0031 17.8 2.2 3.1 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KUM63010.1 - 0.00027 21.5 1.6 0.59 10.8 0.5 3.2 2 1 0 2 2 2 2 Aspartyl protease Corona_3 PF04694.12 KUM63010.1 - 0.026 14.9 0.0 0.1 13.0 0.0 2.0 2 0 0 2 2 2 0 Coronavirus ORF3 protein TAXi_C PF14541.6 KUM63010.1 - 0.048 13.4 0.0 0.14 11.9 0.0 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Se-cys_synth_N PF12390.8 KUM63013.1 - 0.057 13.6 0.1 0.17 12.2 0.1 1.8 1 0 0 1 1 1 0 Selenocysteine synthase N terminal DIT1_PvcA PF05141.12 KUM63014.1 - 7.3e-11 42.1 0.0 9.4e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DUF3510 PF12022.8 KUM63014.1 - 0.053 13.9 0.0 0.065 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) EF1_GNE PF00736.19 KUM63015.1 - 4.7e-33 113.2 1.3 6.8e-33 112.7 1.3 1.2 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KUM63015.1 - 4e-13 49.6 8.3 4e-13 49.6 8.3 2.8 4 0 0 4 4 4 1 Eukaryotic elongation factor 1 beta central acidic region MinC_N PF05209.13 KUM63015.1 - 0.03 14.3 0.1 0.068 13.1 0.0 1.6 2 0 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain UBA2_C PF16195.5 KUM63015.1 - 0.14 12.9 3.7 0.22 12.2 3.7 1.4 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus DNApol_Exo PF18136.1 KUM63016.1 - 4.9e-106 354.0 0.0 8e-106 353.3 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KUM63016.1 - 3.2e-53 181.1 0.0 5.4e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DUF1841 PF08897.11 KUM63016.1 - 0.083 12.9 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) CorA PF01544.18 KUM63017.1 - 2.9e-24 85.9 6.6 2.5e-17 63.2 0.4 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein UPF0052 PF01933.18 KUM63018.1 - 4.5e-61 206.6 0.0 5.6e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 zf-C3HC4_3 PF13920.6 KUM63019.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPT PF03151.16 KUM63020.1 - 8.2e-26 91.0 21.9 9.9e-26 90.7 21.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KUM63020.1 - 0.00016 21.0 20.4 0.0017 17.6 20.4 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KUM63020.1 - 0.51 10.5 36.8 2.2 8.5 12.1 2.4 2 0 0 2 2 2 0 EamA-like transporter family MFS_1 PF07690.16 KUM63021.1 - 2.6e-19 69.4 14.2 2.6e-19 69.4 14.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3145 PF11343.8 KUM63022.1 - 0.057 13.0 0.1 0.21 11.1 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3145) Peripla_BP_4 PF13407.6 KUM63022.1 - 0.12 11.9 0.0 0.52 9.8 0.0 1.8 2 0 0 2 2 2 0 Periplasmic binding protein domain Methyltransf_PK PF05891.12 KUM63023.1 - 1.8e-69 233.6 0.0 2.2e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KUM63023.1 - 0.0005 20.7 0.0 0.0011 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM63023.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KUM63023.1 - 0.035 14.7 0.0 0.066 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SQS_PSY PF00494.19 KUM63024.1 - 3.5e-47 161.1 0.0 4.2e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.23 KUM63025.1 - 4.1e-71 239.5 0.0 5.5e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KUM63025.1 - 3.7e-24 84.5 0.0 1.2e-23 82.9 0.0 1.9 2 0 0 2 2 2 1 HIRAN domain Helicase_C PF00271.31 KUM63025.1 - 1.6e-12 47.8 0.0 4.2e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KUM63025.1 - 0.00017 21.4 8.9 0.00029 20.6 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KUM63025.1 - 0.00092 19.0 7.8 0.0021 17.9 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KUM63025.1 - 0.0048 16.9 0.0 0.015 15.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 KUM63025.1 - 0.0051 16.8 10.2 0.011 15.8 10.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KUM63025.1 - 0.0071 16.2 12.1 0.014 15.3 12.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KUM63025.1 - 0.012 15.9 11.2 0.012 15.9 11.2 1.7 2 0 0 2 2 1 0 Ring finger domain zf-RING_5 PF14634.6 KUM63025.1 - 0.016 15.1 10.8 0.031 14.2 10.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain PLU-1 PF08429.11 KUM63025.1 - 0.017 14.3 0.4 0.03 13.5 0.4 1.3 1 0 0 1 1 1 0 PLU-1-like protein zf-C3HC4_4 PF15227.6 KUM63025.1 - 1.8 8.8 10.9 3.7 7.8 10.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING MFS_1 PF07690.16 KUM63026.1 - 1.3e-32 113.1 82.8 1.8e-28 99.5 62.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM63026.1 - 0.15 10.9 39.1 0.018 13.9 15.9 3.2 2 2 0 2 2 2 0 Sugar (and other) transporter Zn_clus PF00172.18 KUM63027.1 - 1e-09 38.4 7.8 1e-09 38.4 7.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM63027.1 - 0.0075 15.3 5.3 0.22 10.5 5.3 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM63031.1 - 5.5e-07 29.6 14.8 8.3e-07 29.0 14.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PriC PF07445.12 KUM63031.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Primosomal replication protein priC Epimerase PF01370.21 KUM63032.1 - 3.1e-12 46.5 0.0 4.6e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KUM63032.1 - 6.8e-07 29.1 0.1 0.00022 20.9 0.1 2.1 2 0 0 2 2 2 2 NmrA-like family 3Beta_HSD PF01073.19 KUM63032.1 - 5.5e-06 25.6 0.0 1.2e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KUM63032.1 - 6.7e-06 25.7 0.0 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KUM63032.1 - 5.8e-05 23.1 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KUM63032.1 - 0.0002 20.5 0.0 0.092 11.8 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.25 KUM63032.1 - 0.0019 17.7 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Glyco_hydro_47 PF01532.20 KUM63033.1 - 4.8e-181 602.7 0.2 5.6e-181 602.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 KUM63033.1 - 0.018 13.6 0.1 4 5.8 0.0 2.1 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Med20 PF08612.11 KUM63034.1 - 8.3e-79 264.1 0.0 9.5e-79 263.9 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Clathrin_lg_ch PF01086.17 KUM63036.1 - 2.4e-71 240.4 3.3 2.9e-71 240.2 3.3 1.1 1 0 0 1 1 1 1 Clathrin light chain CTD_bind PF04818.13 KUM63037.1 - 3.4e-16 59.8 0.1 8.7e-16 58.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CREPT PF16566.5 KUM63037.1 - 0.031 14.4 0.2 0.064 13.4 0.2 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Glyco_hydro_31 PF01055.26 KUM63038.1 - 2.4e-154 514.8 2.1 3.4e-154 514.3 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KUM63038.1 - 4.8e-31 107.4 0.1 8.7e-31 106.5 0.1 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KUM63038.1 - 0.00068 19.9 0.2 0.0029 17.9 0.2 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like Rotavirus_VP7 PF05868.11 KUM63038.1 - 0.038 13.4 0.1 0.07 12.5 0.1 1.4 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 Fungal_trans PF04082.18 KUM63039.1 - 8.8e-10 38.0 0.2 1.4e-09 37.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.6 KUM63040.1 - 3.6e-16 59.4 0.0 5e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM63040.1 - 4e-12 46.6 0.0 3e-11 43.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM63040.1 - 1.4e-10 41.8 0.0 9.6e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM63040.1 - 7.1e-10 39.5 0.0 9.7e-05 23.0 0.0 2.3 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KUM63040.1 - 1.9e-07 31.0 0.0 8.7e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Prp18 PF02840.15 KUM63040.1 - 0.24 11.4 0.1 0.55 10.3 0.1 1.5 1 0 0 1 1 1 0 Prp18 domain ABC_membrane PF00664.23 KUM63041.1 - 2.6e-52 178.2 9.2 3.4e-52 177.8 9.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KUM63041.1 - 1.8e-36 125.7 0.0 4.5e-36 124.4 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KUM63041.1 - 1.2e-05 24.9 0.0 0.0011 18.5 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KUM63041.1 - 0.004 17.5 0.1 0.015 15.7 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KUM63041.1 - 0.0089 15.7 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 KUM63041.1 - 0.012 16.0 0.0 0.06 13.8 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KUM63041.1 - 0.022 14.5 0.1 0.3 10.8 0.0 2.5 2 1 1 3 3 3 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 KUM63041.1 - 0.031 14.4 0.0 1.6 8.8 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain FAM53 PF15242.6 KUM63041.1 - 0.033 14.0 1.2 0.055 13.3 1.2 1.3 1 0 0 1 1 1 0 Family of FAM53 AAA_22 PF13401.6 KUM63041.1 - 0.035 14.4 0.2 0.28 11.5 0.2 2.2 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KUM63041.1 - 0.048 13.9 1.0 1.4 9.2 0.7 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KUM63041.1 - 0.063 13.0 0.0 0.2 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 KUM63041.1 - 0.076 11.8 0.3 0.27 10.0 0.1 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Ribosomal_S9 PF00380.19 KUM63041.1 - 0.091 13.3 0.4 20 5.7 0.1 2.7 2 1 0 2 2 2 0 Ribosomal protein S9/S16 AAA_25 PF13481.6 KUM63041.1 - 0.16 11.5 0.1 1.2 8.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KUM63041.1 - 0.23 11.9 1.6 0.34 11.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain CDC37_N PF03234.14 KUM63042.1 - 2.1e-49 167.7 2.2 2.1e-49 167.7 2.2 2.5 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KUM63042.1 - 1.1e-41 141.4 0.2 3.6e-41 139.8 0.0 2.0 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KUM63042.1 - 2.7e-34 117.3 2.9 2.5e-33 114.2 2.4 2.6 2 0 0 2 2 2 1 Cdc37 C terminal domain Spc29 PF17082.5 KUM63042.1 - 0.56 10.0 4.1 0.72 9.7 1.5 2.1 1 1 1 2 2 2 0 Spindle Pole Component 29 SNARE PF05739.19 KUM63043.1 - 3.1e-14 52.7 0.7 7e-14 51.6 0.7 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KUM63043.1 - 3.2e-07 30.2 5.7 3.2e-07 30.2 5.7 1.5 2 0 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.6 KUM63043.1 - 0.0071 16.7 1.0 0.0071 16.7 1.0 2.4 2 0 0 2 2 2 1 Syntaxin-like protein HlyD_D4 PF16572.5 KUM63043.1 - 0.0077 16.1 0.0 0.025 14.4 0.0 1.9 1 0 0 1 1 1 1 Long alpha hairpin domain of cation efflux system protein, CusB DUF3357 PF11837.8 KUM63043.1 - 0.058 13.9 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) BBP1_C PF15272.6 KUM63043.1 - 0.076 12.8 8.6 1.3 8.8 0.6 3.2 1 1 1 3 3 3 0 Spindle pole body component BBP1, C-terminal MCPsignal PF00015.21 KUM63043.1 - 0.083 12.7 6.0 0.079 12.8 0.8 2.8 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TPPK_C PF12555.8 KUM63043.1 - 0.089 12.8 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Cauli_DNA-bind PF03310.13 KUM63043.1 - 0.12 12.4 1.5 1.2 9.2 0.2 2.4 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein GCP_C_terminal PF04130.13 KUM63043.1 - 0.31 10.5 1.8 0.38 10.2 0.7 1.7 1 1 0 1 1 1 0 Gamma tubulin complex component C-terminal DNA_repr_REX1B PF14966.6 KUM63043.1 - 0.53 11.0 0.1 0.53 11.0 0.1 3.1 3 1 0 3 3 2 0 DNA repair REX1-B FliD_C PF07195.12 KUM63043.1 - 1.3 8.3 6.3 42 3.4 6.3 2.2 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF641 PF04859.12 KUM63043.1 - 2.2 8.6 7.9 2 8.8 1.2 2.7 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) EF-hand_1 PF00036.32 KUM63044.1 - 2.7e-22 76.6 3.0 2.3e-10 39.3 0.9 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KUM63044.1 - 2.9e-20 71.9 3.9 4.7e-16 58.4 0.6 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 KUM63044.1 - 5e-20 71.7 2.2 6.1e-20 71.5 2.2 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KUM63044.1 - 1.9e-16 58.5 1.0 2.3e-09 36.4 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KUM63044.1 - 6.7e-14 50.7 1.5 3.2e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 EF hand EFhand_Ca_insen PF08726.10 KUM63044.1 - 2.2e-06 27.6 0.2 3.3e-06 27.1 0.2 1.3 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_9 PF14658.6 KUM63044.1 - 2.7e-05 24.4 0.1 3.3e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 KUM63044.1 - 0.00011 22.1 0.4 0.00013 21.9 0.4 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KUM63044.1 - 0.00025 21.3 0.1 0.00029 21.1 0.1 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 KUM63044.1 - 0.00036 21.4 0.1 0.00036 21.4 0.1 1.0 1 0 0 1 1 1 1 EF-hand domain Dockerin_1 PF00404.18 KUM63044.1 - 0.019 15.1 0.9 0.062 13.5 0.9 1.8 1 1 0 1 1 1 0 Dockerin type I domain RuvA_C PF07499.13 KUM63044.1 - 0.089 13.3 0.1 2.7 8.5 0.0 2.1 2 0 0 2 2 2 0 RuvA, C-terminal domain RNA_pol_Rpb4 PF03874.16 KUM63044.1 - 0.096 13.0 0.2 0.19 12.1 0.1 1.5 1 1 0 1 1 1 0 RNA polymerase Rpb4 Homeobox_KN PF05920.11 KUM63045.1 - 6e-22 77.3 0.2 1.1e-21 76.4 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KUM63045.1 - 3.3e-07 30.0 0.1 5.6e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Homeodomain DUF1729 PF08354.10 KUM63046.1 - 0.071 12.0 0.5 0.092 11.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) CCER1 PF15482.6 KUM63046.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Ysc84 PF04366.12 KUM63046.1 - 5.4 6.8 7.4 6.6 6.5 1.3 2.3 1 1 1 2 2 2 0 Las17-binding protein actin regulator DUF4231 PF14015.6 KUM63046.1 - 6.4 7.3 6.3 5 7.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Alpha-amylase PF00128.24 KUM63047.1 - 6.7e-70 236.3 3.4 9.2e-70 235.8 3.4 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KUM63047.1 - 2.2e-18 66.3 0.1 6.4e-18 64.8 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.6 KUM63047.1 - 0.0094 15.1 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Biotin_carb_N PF00289.22 KUM63049.1 - 2.2e-38 131.2 0.0 3.8e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain CPSase_L_D2 PF02786.17 KUM63049.1 - 1e-35 123.2 0.0 1.7e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 KUM63049.1 - 4.2e-08 33.0 0.0 7.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.11 KUM63049.1 - 0.051 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Metallophos PF00149.28 KUM63050.1 - 1.6e-34 120.2 0.1 2.5e-34 119.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KUM63050.1 - 1.1e-12 48.2 0.2 2.3e-12 47.1 0.2 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain FAD_binding_1 PF00667.20 KUM63051.1 - 3.6e-44 151.0 0.0 5.1e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KUM63051.1 - 6.1e-10 39.7 0.0 1.3e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain AA_permease_2 PF13520.6 KUM63052.1 - 1.7e-53 182.0 46.1 2.1e-53 181.7 46.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM63052.1 - 7.8e-23 80.8 37.8 1e-22 80.4 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease Amidase PF01425.21 KUM63053.1 - 3.6e-75 253.6 0.0 4.8e-65 220.3 0.0 2.1 1 1 1 2 2 2 2 Amidase Nup214_FG PF18617.1 KUM63053.1 - 0.8 10.3 6.7 0.48 11.0 4.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup214 phenylalanine-glycine (FG) domain CstA PF02554.14 KUM63055.1 - 0.35 9.7 12.1 0.84 8.5 12.1 1.5 1 1 0 1 1 1 0 Carbon starvation protein CstA Nitroreductase PF00881.24 KUM63056.1 - 2.1e-17 63.7 0.0 2.7e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Pax7 PF12360.8 KUM63056.1 - 0.13 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Paired box protein 7 TM1586_NiRdase PF14512.6 KUM63056.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative TM nitroreductase DUF1682 PF07946.14 KUM63057.1 - 4.3e-111 371.2 0.4 5e-111 371.0 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Polysacc_deac_1 PF01522.21 KUM63058.1 - 2.7e-17 62.8 0.0 4.1e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Creatininase PF02633.14 KUM63058.1 - 1.2e-06 28.1 0.3 1.4e-06 27.9 0.3 1.1 1 0 0 1 1 1 1 Creatinine amidohydrolase Nucleoside_tran PF01733.18 KUM63059.1 - 1.1e-43 149.8 12.8 4.6e-42 144.5 12.8 2.5 1 1 0 1 1 1 1 Nucleoside transporter DUF2207 PF09972.9 KUM63059.1 - 0.063 12.0 2.4 4.3 6.0 0.0 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) CoA_binding_3 PF13727.6 KUM63059.1 - 0.1 12.6 10.1 3 7.8 0.1 3.6 4 0 0 4 4 4 0 CoA-binding domain p450 PF00067.22 KUM63060.1 - 3.3e-75 253.6 0.0 4e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Haspin_kinase PF12330.8 KUM63061.1 - 1.5e-39 136.0 0.0 2.1e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain YppG PF14179.6 KUM63061.1 - 4.6 8.0 0.0 4.6 8.0 0.0 3.0 3 1 0 3 3 3 0 YppG-like protein Zn_clus PF00172.18 KUM63064.1 - 1.6e-07 31.3 6.7 1.6e-07 31.3 6.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF836 PF05768.14 KUM63065.1 - 2.5e-13 50.2 0.0 2.7e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KUM63065.1 - 0.0013 18.9 0.1 0.0022 18.2 0.0 1.5 2 0 0 2 2 2 1 Glutaredoxin TraF PF13728.6 KUM63065.1 - 0.089 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein CHORD PF04968.12 KUM63066.1 - 3e-46 155.9 18.4 2.2e-27 95.5 5.5 3.0 2 1 0 2 2 2 2 CHORD CS PF04969.16 KUM63066.1 - 2.4e-13 50.9 0.0 3.7e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 CS domain FAP PF07174.11 KUM63066.1 - 2.7 7.3 9.5 4.2 6.7 9.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DHquinase_II PF01220.19 KUM63067.1 - 2.2e-61 205.6 0.1 2.5e-61 205.3 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Sortilin-Vps10 PF15902.5 KUM63067.1 - 0.19 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, SBF PF01758.16 KUM63068.1 - 1.6e-41 142.1 21.8 6.3e-23 81.5 2.0 3.5 2 2 3 5 5 5 2 Sodium Bile acid symporter family FA_hydroxylase PF04116.13 KUM63068.1 - 0.18 12.2 0.1 0.18 12.2 0.1 2.8 1 1 1 3 3 3 0 Fatty acid hydroxylase superfamily DUF3425 PF11905.8 KUM63069.1 - 2.7e-12 46.8 0.1 6.9e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) TALPID3 PF15324.6 KUM63069.1 - 0.00055 17.8 0.9 0.00071 17.4 0.9 1.0 1 0 0 1 1 1 1 Hedgehog signalling target MCM2_N PF12619.8 KUM63069.1 - 0.13 12.5 0.4 0.21 11.9 0.4 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 Choline_kinase PF01633.20 KUM63070.1 - 1.4e-41 142.5 0.0 6.1e-40 137.1 0.0 2.2 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.23 KUM63070.1 - 9.9e-08 32.2 0.2 2e-07 31.2 0.2 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fungal_trans_2 PF11951.8 KUM63071.1 - 4.1e-34 118.0 9.7 9.4e-34 116.8 9.7 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM63071.1 - 8.5e-07 29.0 9.4 8.5e-07 29.0 9.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ASXH PF13919.6 KUM63071.1 - 0.11 12.6 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 Asx homology domain DHquinase_I PF01487.15 KUM63072.1 - 1.4e-33 117.0 0.0 2e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KUM63072.1 - 4.2e-20 72.4 0.1 1.6e-19 70.6 0.0 1.9 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KUM63072.1 - 7.1e-19 67.9 0.0 2.1e-18 66.3 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KUM63072.1 - 3.2e-10 39.6 0.1 5.8e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KUM63072.1 - 4.7e-06 26.7 0.1 1.2e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 KUM63072.1 - 0.029 14.5 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KUM63072.1 - 0.059 13.7 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain F420_oxidored PF03807.17 KUM63072.1 - 0.065 13.8 0.0 0.97 10.1 0.1 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.18 KUM63073.1 - 4.9e-21 75.0 0.1 7.7e-21 74.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM63073.1 - 1.9e-06 27.9 14.5 2.9e-06 27.3 14.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3326 PF11805.8 KUM63073.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) Bac_rhamnosid6H PF17389.2 KUM63074.1 - 3.5e-16 59.4 0.3 7.1e-16 58.4 0.0 1.5 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_2_N PF02837.18 KUM63074.1 - 0.00026 20.9 0.0 0.00058 19.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Bac_rhamnosid_N PF08531.10 KUM63074.1 - 0.0096 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_36 PF17167.4 KUM63074.1 - 0.033 12.9 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Sugar_tr PF00083.24 KUM63075.1 - 1.6e-70 238.2 24.5 1.9e-70 238.0 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM63075.1 - 2.6e-17 62.8 30.0 2.7e-08 33.1 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tetraspanin PF00335.20 KUM63075.1 - 0.52 10.0 9.5 0.06 13.1 4.9 1.8 2 0 0 2 2 2 0 Tetraspanin family Glyco_hydro_79C PF16862.5 KUM63076.1 - 3.7e-26 92.0 1.9 1e-25 90.6 1.9 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_127 PF07944.12 KUM63077.1 - 4.5e-134 447.8 0.2 5.2e-134 447.6 0.2 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_92 PF07971.12 KUM63078.1 - 2e-89 300.7 1.6 2.4e-89 300.4 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KUM63078.1 - 2.5e-62 210.9 1.2 2.5e-62 210.9 1.2 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain Bul1_N PF04425.12 KUM63079.1 - 2.7e-06 26.4 0.2 0.0027 16.5 0.0 2.3 2 0 0 2 2 2 2 Bul1 N terminus Bul1_C PF04426.12 KUM63079.1 - 0.00042 19.8 0.1 0.00084 18.8 0.1 1.5 1 0 0 1 1 1 1 Bul1 C terminus Arrestin_N PF00339.29 KUM63079.1 - 0.0023 18.0 0.1 0.017 15.2 0.1 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain PALP PF00291.25 KUM63080.1 - 1.3e-49 169.2 0.0 1.5e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme adh_short PF00106.25 KUM63082.1 - 7.1e-20 71.3 0.0 1.7e-18 66.8 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM63082.1 - 1.1e-14 54.6 0.0 1.3e-13 51.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Metallophos PF00149.28 KUM63083.1 - 1e-11 45.7 0.4 1.8e-11 45.0 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 14-3-3 PF00244.20 KUM63084.1 - 1.4e-09 37.8 0.1 2.4e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 14-3-3 protein Csa1 PF06023.12 KUM63084.1 - 0.082 12.2 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 Nucleoside_tran PF01733.18 KUM63084.1 - 0.12 11.8 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Nucleoside transporter DivIC PF04977.15 KUM63085.1 - 0.042 13.6 8.1 0.74 9.6 1.6 2.5 1 1 1 2 2 2 0 Septum formation initiator Lectin_N PF03954.14 KUM63085.1 - 0.087 12.6 5.1 0.11 12.2 3.6 1.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain CCDC92 PF14916.6 KUM63085.1 - 0.38 10.6 3.5 2.9 7.7 0.3 2.4 2 0 0 2 2 2 0 Coiled-coil domain of unknown function TMPIT PF07851.13 KUM63085.1 - 4 6.6 4.9 6.2 6.0 4.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Cep57_CLD_2 PF14197.6 KUM63085.1 - 4.4 7.5 12.7 14 5.9 12.7 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Mto2_bdg PF12808.7 KUM63085.1 - 4.5 7.7 11.8 0.28 11.5 2.8 2.9 2 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region PHD PF00628.29 KUM63085.1 - 4.5 7.2 15.0 8.7 6.3 15.0 1.5 1 0 0 1 1 1 0 PHD-finger AP_endonuc_2 PF01261.24 KUM63086.1 - 2e-30 105.8 0.1 2.7e-30 105.4 0.1 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel FKBP_C PF00254.28 KUM63087.1 - 3.5e-23 81.7 0.0 4.1e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RhoGAP PF00620.27 KUM63088.1 - 8.6e-47 158.8 0.0 2.4e-46 157.3 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KUM63088.1 - 5.3e-15 55.4 19.6 7.1e-10 39.0 2.5 2.4 2 0 0 2 2 2 2 LIM domain 5_nucleotid PF05761.14 KUM63088.1 - 0.042 12.8 1.4 0.075 11.9 1.4 1.4 1 0 0 1 1 1 0 5' nucleotidase family FLYWCH_u PF16662.5 KUM63088.1 - 0.048 13.7 0.1 0.45 10.6 0.0 2.5 2 0 0 2 2 2 0 FLYWCH-type zinc finger-containing protein 1 CmcI PF04989.12 KUM63088.1 - 0.11 12.1 0.2 0.28 10.8 0.2 1.6 1 0 0 1 1 1 0 Cephalosporin hydroxylase CENP-H PF05837.12 KUM63088.1 - 0.27 11.6 12.6 0.033 14.6 1.3 3.1 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Laminin_II PF06009.12 KUM63088.1 - 0.29 11.1 8.8 1.2 9.2 1.5 2.6 2 0 0 2 2 2 0 Laminin Domain II CENP-F_leu_zip PF10473.9 KUM63088.1 - 0.42 10.6 18.0 0.95 9.5 7.7 3.2 4 0 0 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 KUM63088.1 - 1.1 9.4 9.4 0.15 12.2 4.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4164 PF13747.6 KUM63088.1 - 1.8 8.9 12.9 0.27 11.6 4.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) YabA PF06156.13 KUM63088.1 - 3.9 8.2 9.9 0.37 11.4 3.4 2.7 2 1 1 3 3 3 0 Initiation control protein YabA bZIP_Maf PF03131.17 KUM63088.1 - 4.4 7.9 9.6 0.73 10.4 2.0 2.6 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF4407 PF14362.6 KUM63088.1 - 5.3 6.3 8.7 9.1 5.5 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zn-ribbon_8 PF09723.10 KUM63088.1 - 7 6.9 19.8 0.77 9.9 1.5 4.1 3 1 1 4 4 4 0 Zinc ribbon domain V-ATPase_C PF03223.15 KUM63089.1 - 2.2e-127 425.5 0.1 2.5e-127 425.3 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C NMT PF01233.19 KUM63089.1 - 0.057 13.3 0.3 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Inositol_P PF00459.25 KUM63090.1 - 4.6e-82 275.6 0.0 5.3e-82 275.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Shikimate_dh_N PF08501.11 KUM63091.1 - 9.8e-21 73.8 0.0 2.4e-20 72.6 0.0 1.7 1 1 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KUM63091.1 - 0.00061 19.5 0.1 0.0016 18.2 0.1 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KUM63091.1 - 0.093 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.24 KUM63092.1 - 7.7e-141 470.0 18.7 8.8e-141 469.8 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM63092.1 - 1e-24 87.2 28.6 1e-24 87.2 28.6 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily GFO_IDH_MocA PF01408.22 KUM63093.1 - 1.4e-24 87.2 0.0 1.9e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KUM63093.1 - 1.2e-15 57.5 0.0 2.6e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 KUM63093.1 - 0.0016 18.9 0.0 0.0028 18.1 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 KUM63093.1 - 0.077 13.5 0.1 0.17 12.4 0.0 1.6 2 0 0 2 2 2 0 CoA binding domain Ldh_1_N PF00056.23 KUM63093.1 - 0.19 11.8 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain CoA_binding PF02629.19 KUM63093.1 - 0.19 12.5 0.0 0.4 11.4 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain Gp_dh_N PF00044.24 KUM63093.1 - 0.23 11.8 0.0 0.48 10.8 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain APS_kinase PF01583.20 KUM63094.1 - 1.1e-72 243.1 0.0 1.3e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KUM63094.1 - 5.6e-07 29.8 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KUM63094.1 - 2.4e-05 24.9 0.0 4.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KUM63094.1 - 0.00089 19.7 0.0 0.00089 19.7 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 KUM63094.1 - 0.0091 15.5 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Hpr_kinase_C PF07475.12 KUM63094.1 - 0.054 13.0 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain PEPCK_ATP PF01293.20 KUM63094.1 - 0.057 12.1 0.0 0.078 11.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Zeta_toxin PF06414.12 KUM63094.1 - 0.072 12.4 0.0 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.6 KUM63094.1 - 0.083 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KUM63094.1 - 0.09 13.0 0.0 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KUM63094.1 - 0.15 11.2 0.1 0.29 10.2 0.1 1.4 1 1 0 1 1 1 0 G-protein alpha subunit 4HBT PF03061.22 KUM63095.1 - 5.9e-12 45.8 0.0 1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily F-box-like PF12937.7 KUM63096.1 - 0.0048 16.8 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KUM63096.1 - 0.0062 16.4 0.1 0.014 15.3 0.1 1.7 1 1 0 1 1 1 1 F-box domain GPI2 PF06432.11 KUM63097.1 - 1e-132 441.8 4.8 1.2e-132 441.6 4.8 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase FA_desaturase PF00487.24 KUM63097.1 - 7.3 6.3 9.7 11 5.8 5.3 2.4 2 1 0 2 2 2 0 Fatty acid desaturase Polysacc_deac_1 PF01522.21 KUM63099.1 - 1.4e-18 67.0 0.1 3.4e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 KUM63099.1 - 0.0087 15.7 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) PBP1_TM PF14812.6 KUM63099.1 - 0.97 9.8 9.0 1.8 9.0 9.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fringe PF02434.16 KUM63100.1 - 3.6e-09 36.4 0.0 6.6e-08 32.3 0.0 2.3 2 1 0 2 2 2 1 Fringe-like Glyco_transf_34 PF05637.12 KUM63100.1 - 0.027 14.2 1.0 0.094 12.4 0.5 1.9 2 0 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family Fumble PF03630.14 KUM63101.1 - 1.8e-142 474.4 0.0 2.2e-142 474.1 0.0 1.1 1 0 0 1 1 1 1 Fumble DEAD PF00270.29 KUM63102.1 - 3e-42 144.4 0.0 4.5e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM63102.1 - 1.6e-25 89.6 0.0 3.8e-24 85.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KUM63102.1 - 0.00013 20.8 0.0 0.00017 20.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KUM63102.1 - 0.0033 17.4 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Abhydrolase_3 PF07859.13 KUM63103.1 - 3.6e-37 128.3 0.0 4.3e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KUM63103.1 - 5.2e-06 26.1 0.0 1.2e-05 24.9 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 KUM63103.1 - 7.8e-05 22.3 0.0 0.0091 15.6 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase PF00756.20 KUM63103.1 - 0.00067 19.4 0.0 0.031 13.9 0.0 2.1 2 0 0 2 2 2 1 Putative esterase DUF2974 PF11187.8 KUM63103.1 - 0.0013 18.3 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) AXE1 PF05448.12 KUM63103.1 - 0.011 14.4 0.0 0.12 11.1 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 KUM63103.1 - 0.073 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 KUM63103.1 - 0.21 10.5 0.0 1.3 7.9 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase enzyme PRAP PF15314.6 KUM63104.1 - 0.12 12.9 0.5 0.12 12.9 0.5 2.6 3 0 0 3 3 3 0 Proline-rich acidic protein 1, pregnancy-specific uterine DFP PF04127.15 KUM63105.1 - 9.2e-14 51.7 0.0 1.2e-05 25.3 0.0 3.1 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Atg29_N PF18388.1 KUM63106.1 - 1.2e-27 95.4 1.5 2.5e-27 94.4 1.5 1.6 1 0 0 1 1 1 1 Atg29 N-terminal domain Acatn PF13000.7 KUM63107.1 - 3.8e-163 543.9 18.0 7.6e-81 272.3 8.7 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 MFS_1_like PF12832.7 KUM63107.1 - 0.022 13.6 10.6 0.005 15.8 7.3 1.5 2 0 0 2 2 2 0 MFS_1 like family CENP-O PF09496.10 KUM63108.1 - 6.3e-66 222.4 0.0 9.3e-66 221.8 0.0 1.3 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component DNA_pol_A_exoN PF18305.1 KUM63108.1 - 0.1 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain Lipoxygenase PF00305.19 KUM63111.1 - 8.1e-48 163.3 2.1 2.3e-47 161.9 2.1 1.7 1 1 0 1 1 1 1 Lipoxygenase MFS_1 PF07690.16 KUM63112.1 - 2.1e-30 105.9 31.5 3e-30 105.4 31.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MASE2 PF05230.11 KUM63112.1 - 0.071 13.2 4.3 0.78 9.9 0.4 3.2 3 0 0 3 3 3 0 MASE2 domain Yae1_N PF09811.9 KUM63114.1 - 5.6e-11 42.0 0.2 5.6e-11 42.0 0.2 2.3 2 1 1 3 3 3 1 Essential protein Yae1, N terminal RNase_T PF00929.24 KUM63115.1 - 4.1e-07 30.7 0.0 9.2e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KUM63115.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like VASP_tetra PF08776.11 KUM63116.1 - 0.039 13.5 2.4 0.069 12.7 2.4 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain Peptidase_S64 PF08192.11 KUM63116.1 - 4.4 5.7 4.5 2.6 6.4 2.9 1.4 1 1 0 1 1 1 0 Peptidase family S64 Aldedh PF00171.22 KUM63118.1 - 1.1e-152 508.8 0.3 1.2e-152 508.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family WD40 PF00400.32 KUM63119.1 - 2.4e-98 319.3 25.3 4.6e-13 49.4 0.1 10.5 10 0 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM63119.1 - 7.4e-40 135.2 0.1 0.0011 19.2 0.0 10.1 3 1 8 11 11 10 9 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KUM63119.1 - 4.5e-14 52.1 2.1 0.61 9.0 0.0 8.8 1 1 8 9 9 9 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Amidohydro_2 PF04909.14 KUM63119.1 - 1.1e-10 41.7 0.0 2.3e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase PD40 PF07676.12 KUM63119.1 - 1.8e-06 27.7 1.5 10 6.2 0.0 7.0 8 0 0 8 8 7 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KUM63119.1 - 2.8e-06 26.9 0.0 1.3 8.2 0.0 4.5 3 2 2 5 5 5 2 WD40-like domain Proteasome_A_N PF10584.9 KUM63119.1 - 7.8e-05 22.3 9.1 1.5 8.6 0.0 7.3 8 0 0 8 8 8 1 Proteasome subunit A N-terminal signature DUF746 PF05344.11 KUM63119.1 - 0.0022 17.8 0.7 0.068 13.0 0.1 3.3 3 0 0 3 3 3 1 Domain of Unknown Function (DUF746) Cytochrom_D1 PF02239.16 KUM63119.1 - 0.0035 15.9 0.2 0.97 7.9 0.0 3.1 2 1 1 3 3 3 1 Cytochrome D1 heme domain NACHT PF05729.12 KUM63119.1 - 0.034 14.1 0.2 0.12 12.3 0.2 1.9 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.14 KUM63119.1 - 0.039 13.2 0.5 0.087 12.0 0.5 1.5 1 0 0 1 1 1 0 KAP family P-loop domain Robl_LC7 PF03259.17 KUM63119.1 - 0.041 13.6 0.2 1.4 8.7 0.0 3.8 5 0 0 5 5 5 0 Roadblock/LC7 domain Nbas_N PF15492.6 KUM63119.1 - 0.048 13.0 7.9 2.9 7.1 0.9 4.9 3 1 2 5 5 5 0 Neuroblastoma-amplified sequence, N terminal XPC-binding PF09280.11 KUM63119.1 - 3.5 7.4 5.0 9.2 6.1 0.1 3.3 3 0 0 3 3 3 0 XPC-binding domain Glyco_hydro_18 PF00704.28 KUM63120.1 - 1.7e-78 264.5 0.3 2.1e-78 264.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KUM63120.1 - 6.4e-08 32.9 18.1 1.3e-07 31.9 18.1 1.6 1 0 0 1 1 1 1 Chitin recognition protein GHL15 PF14885.6 KUM63120.1 - 0.07 13.1 0.1 1.7 8.5 0.0 2.3 2 1 0 2 2 2 0 Hypothetical glycosyl hydrolase family 15 NAD_binding_4 PF07993.12 KUM63121.1 - 7.2e-38 130.2 0.0 1.1e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KUM63121.1 - 1.8e-27 96.0 0.0 4.8e-27 94.6 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KUM63121.1 - 4.4e-14 52.5 0.0 7.9e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.23 KUM63121.1 - 5.7e-10 39.1 3.1 1.4e-06 28.1 1.2 2.5 1 1 1 2 2 2 2 FAD binding domain BBE PF08031.12 KUM63121.1 - 7e-09 35.7 0.1 1.6e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like PP-binding PF00550.25 KUM63121.1 - 3.3e-05 24.2 0.0 6.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KUM63121.1 - 0.00011 21.3 0.0 0.00022 20.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KUM63121.1 - 0.00014 21.4 0.0 0.00047 19.7 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase UvrC_HhH_N PF08459.11 KUM63121.1 - 0.02 14.8 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal NAD_binding_10 PF13460.6 KUM63121.1 - 0.025 14.5 0.0 0.074 12.9 0.0 1.8 1 1 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 KUM63121.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 KUM63121.1 - 0.069 12.2 0.7 0.63 9.1 0.0 2.5 3 0 0 3 3 3 0 RmlD substrate binding domain KR PF08659.10 KUM63121.1 - 0.088 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 KR domain Fer4_23 PF18009.1 KUM63121.1 - 0.15 12.5 0.3 12 6.3 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S iron-sulfur cluster binding domain Mob1_phocein PF03637.17 KUM63122.1 - 1.8e-73 246.1 0.1 2.4e-73 245.7 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.18 KUM63123.1 - 1.7e-42 145.5 3.4 1.9e-42 145.3 3.4 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF4082 PF13313.6 KUM63123.1 - 0.13 12.3 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) DUF1674 PF07896.12 KUM63124.1 - 1.9e-19 69.8 2.6 4.1e-19 68.8 2.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Aminotran_3 PF00202.21 KUM63125.1 - 1.1e-112 376.7 0.0 1.4e-112 376.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KUM63125.1 - 0.0002 20.7 0.0 0.00039 19.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Diphthamide_syn PF01866.17 KUM63126.1 - 1.2e-117 392.7 0.0 1.6e-117 392.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein HMGL-like PF00682.19 KUM63127.1 - 1.4e-45 156.0 0.2 2e-45 155.4 0.2 1.2 1 0 0 1 1 1 1 HMGL-like PE PF00934.20 KUM63127.1 - 0.2 12.0 0.2 0.2 12.0 0.2 2.4 2 0 0 2 2 2 0 PE family Bromodomain PF00439.25 KUM63129.1 - 4e-08 33.2 0.0 3.4e-07 30.2 0.0 2.2 1 1 0 1 1 1 1 Bromodomain Glyco_hydro_63 PF03200.16 KUM63130.1 - 1.8e-06 27.0 1.4 1.8e-06 27.0 1.4 4.0 4 1 0 4 4 4 1 Glycosyl hydrolase family 63 C-terminal domain FAM76 PF16046.5 KUM63131.1 - 0.027 13.9 0.7 0.028 13.8 0.7 1.2 1 0 0 1 1 1 0 FAM76 protein DUF4407 PF14362.6 KUM63131.1 - 0.06 12.7 4.5 0.059 12.7 4.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OrfB_IS605 PF01385.19 KUM63131.1 - 0.074 13.3 0.2 0.088 13.0 0.2 1.2 1 0 0 1 1 1 0 Probable transposase SlyX PF04102.12 KUM63131.1 - 0.79 10.4 7.9 1.3 9.7 7.7 1.6 1 1 0 1 1 1 0 SlyX CRIM PF16978.5 KUM63132.1 - 6.6e-40 136.5 0.0 1.2e-39 135.6 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KUM63132.1 - 3e-25 88.6 0.1 5.5e-25 87.8 0.1 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology RFC1 PF08519.12 KUM63133.1 - 2.1e-57 193.7 0.1 5.7e-57 192.3 0.1 1.8 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KUM63133.1 - 1.3e-13 51.1 0.0 3.8e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KUM63133.1 - 4.2e-10 40.2 0.2 1e-09 38.9 0.2 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KUM63133.1 - 7.5e-06 26.0 0.0 2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KUM63133.1 - 0.00011 22.5 0.0 0.00028 21.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain DTHCT PF08070.11 KUM63133.1 - 0.0015 19.3 11.1 0.0015 19.3 11.1 6.7 3 2 3 6 6 4 1 DTHCT (NUC029) region Utp14 PF04615.13 KUM63133.1 - 0.0022 16.7 13.3 0.0022 16.7 13.3 4.0 3 1 1 4 4 3 1 Utp14 protein RuvB_N PF05496.12 KUM63133.1 - 0.0033 17.2 0.0 0.0095 15.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KUM63133.1 - 0.0033 17.8 0.1 0.019 15.4 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KUM63133.1 - 0.0035 17.4 0.0 0.01 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KUM63133.1 - 0.0062 16.3 0.9 0.015 15.0 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KUM63133.1 - 0.0089 16.6 0.3 0.056 14.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KUM63133.1 - 0.01 16.0 0.1 0.01 16.0 0.1 2.2 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 KUM63133.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KUM63133.1 - 0.052 13.5 0.8 0.59 10.0 0.1 2.4 1 1 1 2 2 2 0 NTPase NACHT PF05729.12 KUM63133.1 - 0.067 13.1 0.0 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 KUM63133.1 - 0.96 9.7 3.9 0.55 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ribosomal_L16 PF00252.18 KUM63134.1 - 1.1e-31 109.6 0.1 1.4e-31 109.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DNA_pol3_delta2 PF13177.6 KUM63136.1 - 8e-11 42.0 0.1 1.7e-10 41.0 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KUM63136.1 - 2.8e-06 27.8 0.1 6.5e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KUM63136.1 - 5.4e-05 23.5 0.3 0.00028 21.2 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KUM63136.1 - 0.0013 19.1 1.3 0.0082 16.5 0.5 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KUM63136.1 - 0.0039 17.0 0.4 0.0098 15.6 0.4 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KUM63136.1 - 0.015 15.2 0.0 0.05 13.5 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain Rep_fac_C PF08542.11 KUM63136.1 - 0.032 14.6 0.1 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 Replication factor C C-terminal domain ABC_tran PF00005.27 KUM63136.1 - 0.037 14.5 0.1 0.083 13.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter CtaG_Cox11 PF04442.14 KUM63137.1 - 1.6e-60 203.5 0.0 2.1e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 TMEM135_C_rich PF15982.5 KUM63138.1 - 0.00012 22.7 1.0 0.0021 18.6 0.7 2.7 2 1 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 HLH PF00010.26 KUM63139.1 - 2e-06 27.7 0.0 3.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Abhydrolase_3 PF07859.13 KUM63141.1 - 1.9e-32 112.9 0.1 4e-21 75.9 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KUM63141.1 - 0.23 10.2 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase CLN3 PF02487.17 KUM63142.1 - 8.9e-162 538.7 1.5 1e-161 538.5 1.5 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 KUM63142.1 - 0.0033 16.4 26.6 0.069 12.1 22.6 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Hydrolase PF00702.26 KUM63143.1 - 1.5e-07 31.9 0.0 3.9e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KUM63143.1 - 0.0011 19.1 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KUM63143.1 - 0.023 14.8 0.0 8.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KUM63143.1 - 0.061 13.7 2.7 0.07 13.5 1.0 1.9 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase AA_permease PF00324.21 KUM63144.1 - 7.8e-93 311.6 36.0 9.9e-93 311.3 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM63144.1 - 2.7e-24 85.8 39.4 3.3e-24 85.5 39.4 1.1 1 0 0 1 1 1 1 Amino acid permease Oxidored_FMN PF00724.20 KUM63145.1 - 1.1e-37 130.1 0.0 2.9e-37 128.7 0.0 1.6 2 0 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family DAO PF01266.24 KUM63146.1 - 3.5e-47 161.7 1.1 4e-47 161.5 1.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KUM63146.1 - 0.00025 21.1 1.1 0.069 13.1 0.2 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KUM63146.1 - 0.0087 15.2 0.7 0.29 10.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.6 KUM63146.1 - 0.053 12.7 0.1 0.6 9.2 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KUM63146.1 - 0.055 12.7 1.6 6.5 5.9 1.6 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KUM63146.1 - 0.064 12.5 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family GWT1 PF06423.12 KUM63147.1 - 3.3 7.8 6.6 7.4 6.7 6.1 1.8 1 1 0 1 1 1 0 GWT1 MFS_1 PF07690.16 KUM63148.1 - 1.1e-36 126.5 61.5 1e-26 93.7 31.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KUM63149.1 - 1.3e-22 80.1 1.9 2.2e-22 79.4 0.5 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain AAA_16 PF13191.6 KUM63150.1 - 0.0022 18.4 0.5 0.0092 16.4 0.1 1.9 1 1 0 2 2 2 1 AAA ATPase domain Nbs1_C PF08599.10 KUM63150.1 - 0.014 15.5 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 DUF2075 PF09848.9 KUM63150.1 - 0.027 13.7 0.2 0.5 9.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KUM63150.1 - 0.031 14.4 0.1 0.054 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KUM63150.1 - 0.036 13.6 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KUM63150.1 - 0.043 13.7 0.0 0.089 12.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain KTI12 PF08433.10 KUM63150.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Rgp1 PF08737.10 KUM63151.1 - 1.9e-136 455.6 0.0 3.1e-136 454.9 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 KUM63151.1 - 0.00012 22.2 0.0 0.00038 20.5 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KUM63151.1 - 0.047 14.1 0.0 0.29 11.6 0.0 2.3 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.11 KUM63151.1 - 0.22 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein Neugrin PF06413.11 KUM63152.1 - 2.5e-12 47.3 0.2 2.5e-12 47.3 0.2 2.1 1 1 1 2 2 2 1 Neugrin MRP-L20 PF12824.7 KUM63152.1 - 0.00046 20.4 11.2 0.00046 20.4 11.2 2.7 2 1 1 3 3 3 1 Mitochondrial ribosomal protein subunit L20 TMEM43 PF07787.12 KUM63152.1 - 0.093 12.1 0.9 1.2 8.5 1.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 43 Acyl-CoA_dh_N PF02771.16 KUM63152.1 - 0.82 10.3 6.3 0.36 11.5 0.5 2.2 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain DUF4390 PF14334.6 KUM63153.1 - 0.021 14.2 0.1 0.022 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) WD40 PF00400.32 KUM63154.1 - 4.7e-10 39.9 4.3 0.1 13.5 0.0 6.6 6 1 0 6 6 6 4 WD domain, G-beta repeat SPO22 PF08631.10 KUM63155.1 - 1.5e-34 119.8 0.3 6.8e-34 117.6 0.1 2.3 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 KUM63155.1 - 0.076 13.5 0.0 0.076 13.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat CENP-Q PF13094.6 KUM63159.1 - 3e-50 170.7 6.1 5e-50 170.0 6.1 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit HAP1_N PF04849.13 KUM63159.1 - 0.0029 16.9 3.6 0.0051 16.1 3.6 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region HrpB7 PF09486.10 KUM63159.1 - 0.07 13.5 6.0 0.25 11.7 4.3 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF5622 PF18533.1 KUM63159.1 - 0.18 12.0 1.0 0.41 10.8 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5622) PRKG1_interact PF15898.5 KUM63159.1 - 3.3 8.6 9.9 0.85 10.6 5.3 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF1843 PF08898.10 KUM63159.1 - 9.9 6.8 8.1 3.5 8.2 1.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF1843) Carn_acyltransf PF00755.20 KUM63161.1 - 2e-206 687.1 0.0 2.3e-206 687.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rxt3 PF08642.10 KUM63163.1 - 4.5e-42 143.8 0.1 1.6e-41 142.0 0.0 2.0 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KUM63163.1 - 0.0031 17.6 0.0 0.0077 16.3 0.0 1.6 1 0 0 1 1 1 1 LCCL domain Sulfatase PF00884.23 KUM63164.1 - 3.5e-18 66.0 0.4 5.9e-18 65.3 0.4 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KUM63164.1 - 3e-05 23.8 0.0 6.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KUM63164.1 - 8.7e-05 21.3 0.0 0.00014 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KUM63164.1 - 0.034 13.5 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF2298 PF10060.9 KUM63164.1 - 0.096 11.4 4.8 0.17 10.6 4.8 1.3 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) DUF1501 PF07394.12 KUM63164.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Polysacc_lyase PF14099.6 KUM63165.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide lyase Cupin_3 PF05899.12 KUM63166.1 - 1e-07 31.6 0.3 1.8e-07 30.7 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 KUM63166.1 - 0.0002 21.2 0.0 0.00028 20.7 0.0 1.3 1 1 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_2 PF07883.11 KUM63166.1 - 0.021 14.5 0.1 0.038 13.7 0.1 1.5 1 0 0 1 1 1 0 Cupin domain DUF4437 PF14499.6 KUM63166.1 - 0.059 12.5 0.1 0.11 11.6 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4437) Skp1_POZ PF03931.15 KUM63168.1 - 0.0014 18.7 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain zf-C3HC4_3 PF13920.6 KUM63169.1 - 9.1e-09 35.0 11.9 1.5e-08 34.3 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KUM63169.1 - 0.12 12.2 12.5 0.23 11.3 12.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Penicillinase_R PF03965.16 KUM63170.1 - 0.082 13.3 0.2 2.8 8.3 0.0 3.0 3 0 0 3 3 3 0 Penicillinase repressor Malic_M PF03949.15 KUM63171.1 - 1.1e-90 303.4 0.0 1.4e-90 303.1 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KUM63171.1 - 8.2e-66 221.3 0.0 1.3e-65 220.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Q_salvage PF10343.9 KUM63172.1 - 3.9e-93 312.1 0.0 4.3e-93 312.0 0.0 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1563 PF07599.11 KUM63172.1 - 0.0031 17.6 0.5 0.0058 16.7 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1563) Q_salvage PF10343.9 KUM63173.1 - 5.8e-25 88.4 0.1 8.8e-25 87.8 0.1 1.3 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF4121 PF13497.6 KUM63173.1 - 0.00098 18.3 0.2 0.0014 17.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4121) ThiF PF00899.21 KUM63174.1 - 8.3e-73 244.7 0.0 1.2e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KUM63174.1 - 2.1e-15 57.1 2.4 2.5e-15 56.8 0.3 2.3 3 0 0 3 3 3 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KUM63174.1 - 1.8e-07 31.4 6.9 8.4e-07 29.2 1.1 2.7 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KUM63174.1 - 0.00045 20.6 0.2 0.0041 17.5 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KUM63174.1 - 0.0045 17.1 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UPF0561 PF10573.9 KUM63174.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Pyr_redox PF00070.27 KUM63174.1 - 0.051 14.1 0.1 3.6 8.2 0.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Sec20 PF03908.13 KUM63174.1 - 0.066 13.1 1.4 0.7 9.8 0.2 2.7 2 0 0 2 2 2 0 Sec20 adh_short_C2 PF13561.6 KUM63175.1 - 2.6e-35 122.1 0.5 3.2e-30 105.4 0.0 2.4 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM63175.1 - 2.3e-34 118.6 2.5 2.8e-24 85.7 0.2 2.4 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 KUM63175.1 - 8.1e-11 42.2 0.8 1e-09 38.5 0.1 2.3 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 KUM63175.1 - 2.8e-05 23.7 0.0 9.3e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KUM63175.1 - 0.00015 21.0 0.1 0.0087 15.2 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 KUM63175.1 - 0.0053 17.3 0.0 0.013 16.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 KUM63175.1 - 0.011 15.6 0.4 4.4 7.1 0.0 2.2 1 1 1 2 2 2 0 NAD(P)H-binding Shikimate_DH PF01488.20 KUM63175.1 - 0.021 14.9 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KUM63175.1 - 0.096 12.9 0.1 1.1 9.5 0.1 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ABC_membrane PF00664.23 KUM63176.1 - 5.9e-35 121.2 13.4 9.2e-35 120.6 13.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KUM63176.1 - 9.3e-33 113.6 0.0 1.9e-32 112.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KUM63176.1 - 1.1e-07 31.5 0.0 4.7e-06 26.2 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KUM63176.1 - 0.015 15.6 0.2 0.44 10.8 0.2 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KUM63176.1 - 0.032 14.0 0.2 0.092 12.5 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KUM63176.1 - 0.033 14.6 0.2 0.11 12.8 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 KUM63176.1 - 0.092 12.5 0.1 0.4 10.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KUM63176.1 - 0.14 12.4 0.1 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KUM63176.1 - 0.15 12.0 0.1 1.6 8.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 KUM63176.1 - 0.19 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain zf-ZPR1 PF03367.13 KUM63177.1 - 1.2e-100 334.0 0.0 9.5e-52 175.1 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 KUM63177.1 - 0.013 15.5 0.7 0.53 10.3 0.1 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FeS PF04060.13 KUM63177.1 - 0.078 12.6 0.8 0.19 11.4 0.8 1.7 1 0 0 1 1 1 0 Putative Fe-S cluster Cytochrome_C7 PF14522.6 KUM63177.1 - 0.12 12.4 3.4 0.16 12.0 0.2 2.6 2 2 0 2 2 2 0 Cytochrome c7 and related cytochrome c DUF4028 PF13220.6 KUM63177.1 - 0.12 12.2 0.0 0.44 10.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) Pro_isomerase PF00160.21 KUM63178.1 - 2e-36 125.7 0.0 4.6e-36 124.5 0.0 1.5 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-CDGSH PF09360.10 KUM63178.1 - 0.088 13.0 0.2 0.25 11.6 0.1 1.8 2 0 0 2 2 2 0 Iron-binding zinc finger CDGSH type Glycos_transf_1 PF00534.20 KUM63179.1 - 7.5e-11 41.9 0.0 1.9e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KUM63179.1 - 9.5e-11 42.3 0.0 2.6e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 APH PF01636.23 KUM63179.1 - 6.5e-06 26.2 0.2 6.7e-05 22.9 0.1 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family TIP120 PF08623.10 KUM63180.1 - 2.6e-63 212.7 0.3 1.9e-62 209.9 0.0 2.5 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KUM63180.1 - 1.4e-05 25.4 6.5 1.3 9.4 0.0 6.4 5 2 3 8 8 8 3 HEAT repeats HEAT PF02985.22 KUM63180.1 - 8.7e-05 22.5 13.7 1.1 9.7 0.0 8.5 11 0 0 11 11 11 2 HEAT repeat IFRD PF05004.13 KUM63180.1 - 0.0039 16.3 2.8 0.52 9.4 0.1 3.6 1 1 0 3 3 3 1 Interferon-related developmental regulator (IFRD) Arm PF00514.23 KUM63180.1 - 0.05 13.7 0.4 5 7.3 0.0 3.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 KUM63180.1 - 0.078 13.3 0.1 2.5 8.5 0.0 3.1 1 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Spectrin_like PF18373.1 KUM63180.1 - 0.12 12.5 0.1 0.33 11.0 0.1 1.8 1 0 0 1 1 1 0 Spectrin like domain HEAT_EZ PF13513.6 KUM63180.1 - 0.17 12.4 14.9 6.6 7.4 0.0 8.0 8 2 2 10 10 10 0 HEAT-like repeat HEAT_PBS PF03130.16 KUM63180.1 - 0.69 10.8 3.8 4.9 8.1 0.4 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Methyltransf_23 PF13489.6 KUM63181.1 - 5.7e-08 32.8 0.0 7.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM63181.1 - 3.1e-05 24.6 0.0 0.0001 22.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KUM63181.1 - 0.0075 15.7 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 KUM63181.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KUM63181.1 - 0.25 10.9 0.0 0.42 10.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain RTP1_C1 PF10363.9 KUM63182.1 - 2.1e-29 102.0 0.1 4e-28 97.8 0.1 3.0 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KUM63182.1 - 3.6e-06 26.5 0.0 1.2e-05 24.9 0.0 2.0 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_EZ PF13513.6 KUM63182.1 - 0.85 10.2 4.9 15 6.2 0.0 4.8 5 1 1 6 6 6 0 HEAT-like repeat DBR1 PF05011.13 KUM63183.1 - 1.3e-38 132.5 0.0 3e-38 131.4 0.0 1.6 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain ORC6 PF05460.13 KUM63184.1 - 3.1e-28 99.1 0.0 3.7e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Augurin PF15187.6 KUM63184.1 - 0.017 15.3 0.1 0.027 14.6 0.1 1.4 1 0 0 1 1 1 0 Oesophageal cancer-related gene 4 ORC6 PF05460.13 KUM63185.1 - 9.1e-20 71.2 0.3 1e-19 71.0 0.3 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) T2SSF PF00482.23 KUM63185.1 - 0.082 12.9 0.0 0.096 12.6 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F CFEM PF05730.11 KUM63186.1 - 7.4e-15 54.8 10.0 1.4e-14 53.9 10.0 1.5 1 0 0 1 1 1 1 CFEM domain CCDC53 PF10152.9 KUM63186.1 - 1.6 9.1 4.3 2 8.8 4.0 1.3 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex SOG2 PF10428.9 KUM63186.1 - 7.3 5.7 17.7 8.8 5.4 17.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Arrestin_C PF02752.22 KUM63188.1 - 2e-13 51.0 0.5 1.4e-12 48.3 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DNA_pol_delta_4 PF04081.13 KUM63190.1 - 7.1e-35 120.2 1.4 8.7e-35 119.9 1.4 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 PGBA_C PF15437.6 KUM63190.1 - 0.028 14.8 2.2 0.049 14.0 2.2 1.4 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal ThiF PF00899.21 KUM63191.1 - 6.7e-15 55.1 0.0 2.9e-14 53.0 0.0 2.1 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 KUM63191.1 - 0.18 12.0 0.2 7.5 6.8 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle tRNA_int_end_N2 PF12928.7 KUM63192.1 - 1e-29 102.5 0.0 2.4e-29 101.3 0.0 1.7 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KUM63192.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Melibiase PF02065.18 KUM63193.1 - 1.5e-151 504.2 0.0 1.9e-151 503.9 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KUM63193.1 - 3.2e-83 279.2 0.0 4.6e-83 278.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 KUM63193.1 - 4e-22 78.5 0.0 7.8e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 KUM63193.1 - 1e-06 28.1 0.0 1.6e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 SMN PF06003.12 KUM63194.1 - 1.8e-07 30.7 3.9 7.8e-05 22.1 1.2 2.1 2 0 0 2 2 2 2 Survival motor neuron protein (SMN) RRM_1 PF00076.22 KUM63195.1 - 3.7e-13 49.1 0.0 9.1e-13 47.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KUM63195.1 - 0.014 15.4 0.2 0.21 11.6 0.1 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RL PF17797.1 KUM63195.1 - 0.066 13.2 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 RL domain Troponin-I_N PF11636.8 KUM63196.1 - 0.0065 16.4 0.1 0.018 15.0 0.1 1.7 1 0 0 1 1 1 1 Troponin I residues 1-32 Thiolase_N PF00108.23 KUM63197.1 - 3.7e-15 56.0 0.0 1.3e-14 54.2 0.0 1.9 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KUM63197.1 - 1.4e-12 47.4 0.7 4.5e-11 42.5 0.7 2.5 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KUM63197.1 - 1.2e-06 28.3 0.1 9.1e-05 22.2 0.0 2.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 KUM63197.1 - 0.0082 14.9 0.2 0.041 12.6 0.1 2.0 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 KUM63197.1 - 0.01 15.4 0.5 0.038 13.6 0.5 1.7 1 1 1 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Peptidase_S49 PF01343.18 KUM63197.1 - 0.051 13.5 0.0 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 CHD5 PF04420.14 KUM63198.1 - 1.5e-60 203.7 3.5 1.8e-60 203.4 3.5 1.1 1 0 0 1 1 1 1 CHD5-like protein Poty_coat PF00767.18 KUM63198.1 - 0.043 13.4 0.3 0.062 12.8 0.3 1.2 1 0 0 1 1 1 0 Potyvirus coat protein DUF3431 PF11913.8 KUM63201.1 - 2.3e-67 226.9 0.0 2.8e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Neurensin PF14927.6 KUM63202.1 - 0.31 10.8 2.8 1.5 8.5 2.8 2.0 1 1 0 1 1 1 0 Neurensin DUF3093 PF11292.8 KUM63202.1 - 0.96 9.7 5.1 0.32 11.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) PPTA PF01239.22 KUM63203.1 - 0.0002 21.0 6.0 0.34 10.7 0.0 3.3 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat Rad10 PF03834.14 KUM63204.1 - 6e-48 161.6 0.3 9.4e-48 161.0 0.3 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KUM63204.1 - 3e-05 24.5 0.0 5.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 KUM63204.1 - 0.00036 20.3 0.0 0.0008 19.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.7 KUM63204.1 - 0.027 14.6 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif RsbRD_N PF14361.6 KUM63204.1 - 0.53 11.0 3.4 0.43 11.3 1.3 1.9 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain p450 PF00067.22 KUM63205.1 - 3.4e-59 200.8 0.0 4.5e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 KUM63208.1 - 1.9e-10 40.9 0.0 5.1e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM63208.1 - 5.2e-06 26.3 0.0 9.7e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.26 KUM63209.1 - 8.1e-69 232.0 0.0 1.9e-68 230.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 KUM63209.1 - 2.5e-67 227.3 0.0 4.4e-67 226.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KUM63209.1 - 6.3e-64 216.3 0.0 1e-63 215.6 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 KUM63209.1 - 3.5e-45 154.5 0.0 6.6e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KUM63209.1 - 2.6e-44 151.3 0.0 4.6e-43 147.2 0.0 2.5 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KUM63209.1 - 2.6e-40 138.9 0.1 5.5e-40 137.8 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KUM63209.1 - 1.6e-30 105.5 0.1 4.3e-30 104.2 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KUM63209.1 - 5.9e-30 104.3 0.0 1.6e-28 99.6 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KUM63209.1 - 1.2e-17 64.1 1.0 1.4e-09 38.1 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KUM63209.1 - 1.6e-14 54.3 0.0 5.1e-14 52.7 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 KUM63209.1 - 4.8e-10 39.3 0.0 9.9e-08 31.7 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_12 PF08242.12 KUM63209.1 - 6.7e-09 36.4 0.2 4.1e-08 33.9 0.0 2.6 3 0 0 3 3 1 1 Methyltransferase domain adh_short PF00106.25 KUM63209.1 - 1.3e-07 31.2 0.1 1e-05 25.1 0.0 3.4 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_11 PF08241.12 KUM63209.1 - 3.7e-07 30.7 0.0 1.3e-06 28.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM63209.1 - 1.2e-06 29.1 0.1 7e-06 26.7 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM63209.1 - 1.2e-05 25.2 0.0 3.6e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KUM63209.1 - 1.4e-05 24.6 0.9 2.6e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.19 KUM63209.1 - 0.00012 21.2 0.0 0.00021 20.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KUM63209.1 - 0.0011 18.4 0.0 0.039 13.3 0.0 2.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Methyltransf_31 PF13847.6 KUM63209.1 - 0.043 13.6 0.0 0.16 11.8 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Helicase_RecD PF05127.14 KUM63209.1 - 0.072 12.9 0.3 0.59 10.0 0.0 2.3 2 0 0 2 2 2 0 Helicase zf-CHCC PF10276.9 KUM63210.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger domain TRAM_LAG1_CLN8 PF03798.16 KUM63211.1 - 5.5e-42 143.8 20.1 5.5e-42 143.8 20.1 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KUM63211.1 - 1.3e-16 60.0 0.0 2.9e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 TRAM1-like protein Mt_ATP-synt_B PF05405.14 KUM63212.1 - 0.049 13.3 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) RasGEF PF00617.19 KUM63213.1 - 3.1e-57 193.6 0.0 5.3e-57 192.9 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KUM63213.1 - 9e-24 83.7 0.1 2.1e-23 82.5 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif MFS_1 PF07690.16 KUM63214.1 - 2.9e-16 59.3 35.7 7.4e-16 58.0 33.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM63214.1 - 6.4e-07 28.2 7.2 6.4e-07 28.2 7.2 1.7 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4131 PF13567.6 KUM63214.1 - 8.1 6.1 8.8 7.7 6.1 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SnoaL_2 PF12680.7 KUM63215.1 - 0.016 15.8 0.0 0.019 15.6 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.6 KUM63215.1 - 0.094 13.1 0.0 0.2 12.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) ETRAMP PF09716.10 KUM63216.1 - 0.8 9.8 5.6 13 6.0 0.0 4.0 3 2 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF3995 PF13160.6 KUM63216.1 - 1 9.7 9.5 0.45 10.9 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) AMP-binding PF00501.28 KUM63217.1 - 3.6e-75 253.2 0.0 5.2e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KUM63217.1 - 8e-49 166.5 0.0 2.4e-23 82.6 0.0 3.4 2 2 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KUM63217.1 - 2.5e-12 47.0 0.0 6.9e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM63217.1 - 0.0019 19.2 0.9 0.21 12.6 0.0 3.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Fungal_trans_2 PF11951.8 KUM63218.1 - 4.4e-09 35.6 2.5 4.8e-09 35.5 0.1 2.1 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM63218.1 - 5.6e-06 26.4 15.0 5.6e-06 26.4 15.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRO1 PF03097.18 KUM63220.1 - 4.5e-121 404.3 0.0 8.8e-121 403.4 0.0 1.5 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KUM63220.1 - 1.4e-84 283.9 4.7 2.3e-84 283.2 4.7 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV HTH_1 PF00126.27 KUM63220.1 - 4 7.5 5.6 4.3 7.4 0.0 3.6 4 0 0 4 4 4 0 Bacterial regulatory helix-turn-helix protein, lysR family Mito_carr PF00153.27 KUM63221.1 - 3e-42 142.5 3.7 1.5e-15 56.9 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein TRAM_LAG1_CLN8 PF03798.16 KUM63222.1 - 7.4e-35 120.5 20.1 7.4e-35 120.5 20.1 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KUM63222.1 - 5.3e-23 80.5 0.0 1.4e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein Septin PF00735.18 KUM63223.1 - 2.6e-113 378.0 0.3 4e-113 377.4 0.3 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KUM63223.1 - 2.2e-07 31.0 0.0 4.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KUM63223.1 - 3.4e-06 27.0 0.6 3.3e-05 23.8 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KUM63223.1 - 3.9e-06 26.6 3.7 4e-05 23.2 0.3 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KUM63223.1 - 0.00065 20.0 0.4 0.0022 18.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 KUM63223.1 - 0.0029 17.1 0.1 0.0052 16.3 0.1 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 KUM63223.1 - 0.006 16.8 0.1 0.013 15.7 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KUM63223.1 - 0.0079 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family FOXP-CC PF16159.5 KUM63223.1 - 0.0086 16.7 1.0 0.032 14.9 1.0 1.9 1 0 0 1 1 1 1 FOXP coiled-coil domain IIGP PF05049.13 KUM63223.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 KUM63223.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KUM63223.1 - 0.024 15.0 0.1 0.095 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Ras PF00071.22 KUM63223.1 - 0.042 13.4 0.6 0.13 11.8 0.4 2.0 2 1 0 2 2 2 0 Ras family KAP_NTPase PF07693.14 KUM63223.1 - 0.044 13.0 0.0 0.058 12.6 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.27 KUM63223.1 - 0.046 14.2 0.1 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 KUM63223.1 - 0.053 13.4 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 KUM63223.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 KUM63223.1 - 0.13 12.1 0.3 5.1 6.8 0.3 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 KUM63223.1 - 0.17 12.3 0.0 0.45 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.17 KUM63223.1 - 0.21 11.4 0.9 13 5.4 0.1 2.7 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KUM63223.1 - 0.6 10.2 6.0 6.1 6.9 0.1 3.1 2 1 1 3 3 3 0 Dynamin family AAA_11 PF13086.6 KUM63223.1 - 3.2 7.5 6.1 23 4.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Casc1_N PF15927.5 KUM63223.1 - 7.1 6.3 14.0 0.24 11.1 7.5 1.8 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus WD40 PF00400.32 KUM63224.1 - 1.7e-12 47.6 2.8 0.0013 19.5 0.5 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Asparaginase PF00710.20 KUM63225.1 - 3.9e-59 199.4 0.0 5.7e-59 198.9 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KUM63225.1 - 4.6e-22 78.4 0.3 4.6e-13 49.4 0.0 2.7 2 0 0 2 2 2 2 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KUM63225.1 - 3.2e-08 34.0 0.1 8.1e-08 32.8 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM63225.1 - 5.5e-07 30.0 0.3 0.00027 21.5 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KUM63225.1 - 9.6e-07 29.0 1.1 0.00061 20.1 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KUM63225.1 - 1.4e-06 28.2 0.5 0.0027 18.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KUM63225.1 - 1.7e-05 25.0 0.0 4.2e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Porphobil_deam PF01379.20 KUM63226.1 - 3.1e-60 203.2 0.0 3.8e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KUM63226.1 - 1.8e-13 50.6 0.0 3.6e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DOPA_dioxygen PF08883.11 KUM63227.1 - 1.4e-37 128.1 0.1 1.8e-37 127.7 0.1 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Glyoxalase PF00903.25 KUM63228.1 - 1.3e-18 67.4 0.2 9.8e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KUM63228.1 - 1.7e-10 41.1 0.1 0.00014 22.1 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 KUM63228.1 - 5.6e-07 29.8 0.0 1.2e-05 25.5 0.0 2.7 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 KUM63228.1 - 0.00012 22.3 0.1 0.86 9.7 0.0 2.9 2 2 1 3 3 3 2 Glyoxalase-like domain Aminotran_1_2 PF00155.21 KUM63229.1 - 3.1e-13 49.6 0.0 4e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KUM63229.1 - 2.3e-05 23.4 0.0 0.00014 20.8 0.0 1.9 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Fungal_trans PF04082.18 KUM63230.1 - 0.00041 19.5 0.0 0.0018 17.4 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain CCDC53 PF10152.9 KUM63230.1 - 0.79 10.1 3.3 1 9.8 1.5 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex MSA-2c PF12238.8 KUM63230.1 - 3.4 7.6 5.8 8.2 6.4 5.8 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c LCCL PF03815.19 KUM63231.1 - 4.6e-24 84.4 0.0 7.1e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 LCCL domain MFS_1 PF07690.16 KUM63232.1 - 9.8e-48 162.9 54.9 3.7e-42 144.5 41.8 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_r1t_holin PF16945.5 KUM63232.1 - 0.0061 16.7 0.9 0.02 15.1 0.9 1.8 1 0 0 1 1 1 1 Putative lactococcus lactis phage r1t holin FMN_dh PF01070.18 KUM63233.1 - 1.2e-110 369.9 0.0 1.4e-110 369.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KUM63233.1 - 3.1e-19 68.9 0.0 6.9e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.15 KUM63233.1 - 0.00079 18.9 0.3 0.0014 18.1 0.3 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KUM63233.1 - 0.0011 18.1 0.4 0.0038 16.3 0.2 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KUM63233.1 - 0.002 17.4 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KUM63233.1 - 0.029 13.7 0.1 0.85 8.9 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF1100 PF06500.11 KUM63234.1 - 9.4e-11 41.1 0.0 1.1e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.18 KUM63234.1 - 1e-05 25.3 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KUM63234.1 - 6.8e-05 22.4 0.0 0.00018 21.0 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KUM63234.1 - 0.0015 18.5 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 KUM63234.1 - 0.0032 17.2 0.0 0.015 15.0 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 KUM63234.1 - 0.026 15.1 1.3 0.026 15.1 1.3 1.5 1 1 1 2 2 2 0 Alpha/beta hydrolase family TPR_16 PF13432.6 KUM63234.1 - 0.13 13.0 1.2 0.28 11.9 1.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 KUM63234.1 - 0.13 11.5 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 adh_short_C2 PF13561.6 KUM63235.1 - 1e-55 188.9 0.4 1.8e-55 188.1 0.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM63235.1 - 9.8e-48 162.2 1.4 1.2e-47 161.9 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM63235.1 - 6.4e-17 62.0 1.2 8.5e-17 61.6 1.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM63235.1 - 0.0082 15.6 0.6 0.012 15.1 0.6 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KUM63235.1 - 0.011 15.0 0.1 0.61 9.4 0.0 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 KUM63235.1 - 0.04 13.3 0.1 0.062 12.7 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF2855 PF11017.8 KUM63235.1 - 0.1 12.3 0.8 11 5.7 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2855) CABS1 PF15367.6 KUM63235.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 NmrA PF05368.13 KUM63235.1 - 0.62 9.6 3.4 0.45 10.0 1.6 1.7 2 0 0 2 2 2 0 NmrA-like family Cu-oxidase_3 PF07732.15 KUM63237.1 - 4.5e-41 139.6 1.0 4.5e-41 139.6 1.0 3.5 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KUM63237.1 - 1.1e-38 132.1 13.8 1e-36 125.7 4.5 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KUM63237.1 - 2.3e-34 118.8 3.5 1.9e-33 115.9 0.0 3.2 4 0 0 4 4 4 1 Multicopper oxidase ACT_7 PF13840.6 KUM63238.1 - 1.2e-25 89.0 0.4 2.2e-17 62.6 0.1 3.4 3 0 0 3 3 3 3 ACT domain Scytalone_dh PF02982.14 KUM63239.1 - 4.8e-79 263.7 3.5 5.9e-79 263.4 3.5 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KUM63239.1 - 2.8e-08 33.9 2.1 3.5e-08 33.6 2.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain Transposase_24 PF03004.14 KUM63240.1 - 0.11 12.7 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) Nyv1_N PF09426.10 KUM63241.1 - 0.064 13.3 2.3 0.071 13.1 2.3 1.2 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal DUF1943 PF09172.11 KUM63241.1 - 3.3 6.8 5.4 4.2 6.5 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Turandot PF07240.11 KUM63241.1 - 8.5 6.4 5.9 4.6 7.3 0.4 2.7 2 1 1 3 3 3 0 Stress-inducible humoral factor Turandot FAD_binding_3 PF01494.19 KUM63243.1 - 2.6e-66 224.2 0.0 3.6e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KUM63243.1 - 5.1e-33 114.5 0.0 8.2e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 KUM63243.1 - 0.029 14.0 0.1 0.14 11.7 0.1 2.0 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KUM63243.1 - 0.067 13.8 0.0 0.26 11.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM63243.1 - 0.12 11.6 0.0 0.43 9.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KUM63243.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 KUM63243.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4534 PF15049.6 KUM63244.1 - 0.035 13.9 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) ANAPC4_WD40 PF12894.7 KUM63245.1 - 8.4e-08 32.4 0.1 0.0028 17.9 0.0 3.2 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KUM63245.1 - 4e-07 30.6 2.6 0.1 13.5 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ PF01011.21 KUM63245.1 - 5.7e-06 26.0 0.5 0.072 13.1 0.1 2.7 2 0 0 2 2 2 2 PQQ enzyme repeat VID27 PF08553.10 KUM63245.1 - 0.00099 18.3 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain Fungal_trans PF04082.18 KUM63246.1 - 1.8e-08 33.8 0.0 7e-08 31.8 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Syntaxin-6_N PF09177.11 KUM63248.1 - 4.4e-26 91.3 1.4 1.1e-25 90.0 0.3 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal DUF4795 PF16043.5 KUM63248.1 - 4.1e-05 23.3 3.2 0.00014 21.6 3.4 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) SNARE PF05739.19 KUM63248.1 - 0.00026 20.9 4.9 0.00042 20.3 0.6 2.5 2 0 0 2 2 2 1 SNARE domain Prominin PF05478.11 KUM63248.1 - 0.00073 17.6 0.1 0.001 17.2 0.1 1.2 1 0 0 1 1 1 1 Prominin ApoLp-III PF07464.11 KUM63248.1 - 0.0037 17.4 2.5 0.034 14.2 1.2 2.5 2 1 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) LXG PF04740.12 KUM63248.1 - 0.04 13.6 3.5 0.16 11.7 0.6 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF2205 PF10224.9 KUM63248.1 - 0.056 13.4 1.8 7.7 6.6 0.0 3.3 3 0 0 3 3 3 0 Short coiled-coil protein Use1 PF09753.9 KUM63248.1 - 0.067 12.9 0.7 0.11 12.2 0.7 1.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF883 PF05957.13 KUM63248.1 - 0.092 13.4 2.7 4.9 7.8 0.0 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) MCPsignal PF00015.21 KUM63248.1 - 0.1 12.4 0.6 4.6 7.0 0.1 2.3 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Seryl_tRNA_N PF02403.22 KUM63248.1 - 0.1 12.8 0.9 0.5 10.6 0.2 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.12 KUM63248.1 - 0.13 12.3 1.9 1.3 9.1 0.9 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus STAT_alpha PF01017.20 KUM63248.1 - 0.13 12.2 3.3 0.41 10.5 3.4 1.9 1 1 0 1 1 1 0 STAT protein, all-alpha domain DUF1664 PF07889.12 KUM63248.1 - 0.13 12.3 4.5 1.6 8.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 KUM63248.1 - 0.13 12.6 1.1 0.25 11.8 0.2 1.8 2 0 0 2 2 2 0 Syntaxin-like protein T3SS_needle_F PF09392.10 KUM63248.1 - 0.14 12.4 1.5 16 5.7 0.1 3.3 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DUF3921 PF13060.6 KUM63248.1 - 0.16 12.0 0.8 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3921) NPV_P10 PF05531.12 KUM63248.1 - 0.19 12.2 6.0 17 6.0 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein APG17 PF04108.12 KUM63248.1 - 0.2 10.8 5.9 1.4 8.0 1.9 2.4 2 1 0 2 2 2 0 Autophagy protein Apg17 DUF2072 PF09845.9 KUM63248.1 - 0.23 11.7 1.8 0.26 11.6 0.4 1.8 1 1 1 2 2 2 0 Zn-ribbon containing protein ATG16 PF08614.11 KUM63248.1 - 0.54 10.5 11.6 1.1 9.4 4.4 2.2 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) OmpH PF03938.14 KUM63248.1 - 0.7 10.2 7.7 27 5.1 7.6 2.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TMF_DNA_bd PF12329.8 KUM63248.1 - 0.92 9.5 5.1 0.89 9.6 0.2 2.9 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 KUM63248.1 - 2.5 8.2 11.9 1.1 9.3 1.2 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Nnf1 PF03980.14 KUM63248.1 - 3.5 8.0 7.7 0.68 10.3 0.2 2.7 2 1 0 2 2 2 0 Nnf1 Spc7 PF08317.11 KUM63248.1 - 8.8 5.1 9.0 2.2 7.1 3.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein NmrA PF05368.13 KUM63250.1 - 8.4e-71 238.2 0.0 1e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAP PF00956.18 KUM63251.1 - 3.9e-32 111.5 8.6 7.9e-29 100.7 3.3 2.3 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) NAAA-beta PF15508.6 KUM63252.1 - 8.6e-16 58.0 0.1 1.4e-15 57.3 0.1 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Zwint PF15556.6 KUM63252.1 - 0.086 12.3 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 ZW10 interactor Fungal_trans PF04082.18 KUM63253.1 - 1.9e-15 56.6 0.9 5.8e-15 55.0 0.8 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM63253.1 - 2.5e-05 24.3 10.9 4.3e-05 23.5 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L4 PF00573.22 KUM63254.1 - 2.2e-39 135.2 0.5 3.1e-39 134.7 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KUM63254.1 - 2.1e-30 104.6 1.6 2.1e-30 104.6 1.6 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Glyco_hydro_61 PF03443.14 KUM63255.1 - 0.0013 18.7 0.1 0.0045 16.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 PRCC PF10253.9 KUM63255.1 - 0.64 10.8 8.6 1 10.1 8.6 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 KUM63255.1 - 7.5 5.6 13.6 9 5.4 13.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SKIP_SNW PF02731.15 KUM63257.1 - 4.4e-72 241.0 3.6 4.4e-72 241.0 3.6 2.3 2 0 0 2 2 2 1 SKIP/SNW domain Nucleo_P87 PF07267.11 KUM63257.1 - 0.68 8.7 8.0 1.5 7.6 8.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3395 PF11875.8 KUM63258.1 - 5.6e-25 88.1 0.6 1.3e-24 86.8 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KUM63258.1 - 1.8e-17 63.2 0.2 4.2e-17 62.0 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain NumbF PF06311.12 KUM63258.1 - 0.076 13.6 0.2 0.19 12.3 0.2 1.6 1 0 0 1 1 1 0 NUMB domain HNH_2 PF13391.6 KUM63259.1 - 2.4e-08 34.0 0.1 3.8e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 HNH endonuclease UPF0029 PF01205.19 KUM63260.1 - 7.4e-35 119.5 0.1 1.1e-34 118.9 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KUM63260.1 - 1.6e-06 28.4 0.0 2.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 RWD domain adh_short PF00106.25 KUM63261.1 - 2.4e-14 53.3 0.3 3.9e-14 52.5 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM63261.1 - 6.9e-13 48.7 0.2 1.2e-12 47.9 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KUM63261.1 - 1.3e-06 28.4 0.9 2.1e-06 27.8 0.4 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KUM63261.1 - 2.1e-06 27.5 2.1 4.2e-06 26.5 2.1 1.5 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KUM63261.1 - 0.00024 20.6 0.1 0.00038 20.0 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KUM63261.1 - 0.0018 18.2 0.1 0.0059 16.5 0.1 1.7 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KUM63261.1 - 0.0084 15.5 0.2 0.017 14.6 0.1 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KUM63261.1 - 0.01 16.3 0.3 0.042 14.3 0.1 2.0 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF1776 PF08643.10 KUM63261.1 - 0.03 13.7 0.0 0.067 12.6 0.0 1.7 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) DapB_N PF01113.20 KUM63261.1 - 0.047 13.8 1.1 0.11 12.6 0.7 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 KUM63261.1 - 0.2 11.7 1.2 0.66 10.0 0.3 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase E1-E2_ATPase PF00122.20 KUM63263.1 - 6.9e-51 172.3 0.3 2.7e-50 170.4 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 KUM63263.1 - 7.3e-48 160.9 2.7 1.3e-13 51.1 0.0 5.5 5 0 0 5 5 5 4 Heavy-metal-associated domain Hydrolase PF00702.26 KUM63263.1 - 3.4e-33 115.7 0.0 6.4e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KUM63263.1 - 2.4e-07 30.8 0.1 0.00087 19.1 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KUM63263.1 - 0.00058 20.3 0.0 0.0017 18.8 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CmcI PF04989.12 KUM63263.1 - 0.069 12.8 0.1 0.44 10.2 0.0 2.4 3 0 0 3 3 3 0 Cephalosporin hydroxylase Cadherin_4 PF17803.1 KUM63263.1 - 0.4 11.4 4.1 2.7 8.7 0.0 3.2 3 0 0 3 3 3 0 Bacterial cadherin-like domain ERCC4 PF02732.15 KUM63264.1 - 5.8e-25 88.3 0.0 8.3e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 ERCC4 domain Epimerase PF01370.21 KUM63266.1 - 4.6e-20 72.1 0.0 5.6e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM63266.1 - 2.2e-13 50.3 0.1 1.8e-12 47.3 0.1 2.1 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KUM63266.1 - 4.6e-12 45.5 0.0 5.9e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KUM63266.1 - 1.4e-06 27.6 0.0 4.1e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KUM63266.1 - 3.5e-06 26.4 0.1 0.083 12.0 0.0 2.7 2 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KUM63266.1 - 0.00052 20.0 0.0 0.00076 19.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KUM63266.1 - 0.0026 17.7 0.0 0.4 10.6 0.0 2.3 1 1 0 2 2 2 1 KR domain Ldh_1_N PF00056.23 KUM63266.1 - 0.0052 16.9 0.0 0.0093 16.1 0.0 1.5 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KUM63266.1 - 0.014 14.6 0.0 0.11 11.6 0.0 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 KUM63266.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.7 1 1 0 1 1 1 0 short chain dehydrogenase ChAPs PF09295.10 KUM63268.1 - 5.9e-156 519.4 0.0 7.5e-156 519.1 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 KUM63268.1 - 0.00016 22.2 2.8 0.14 13.0 0.1 4.1 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KUM63268.1 - 0.0003 20.5 0.1 5.1 7.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KUM63268.1 - 0.00044 20.7 0.0 1.6 9.3 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KUM63268.1 - 0.00046 20.1 0.6 0.57 10.4 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KUM63268.1 - 0.00099 18.4 1.5 0.21 10.8 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KUM63268.1 - 0.0037 17.5 0.2 3.7 7.9 0.1 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KUM63268.1 - 0.0066 16.6 0.1 4.8 7.6 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KUM63268.1 - 0.007 16.3 0.5 11 6.3 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KUM63268.1 - 0.078 13.1 0.2 2.4 8.4 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPT PF03151.16 KUM63269.1 - 8.3e-25 87.7 29.7 1e-24 87.5 29.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KUM63269.1 - 0.32 10.2 28.0 0.81 8.8 28.0 1.7 1 1 0 1 1 1 0 UAA transporter family Mid2 PF04478.12 KUM63270.1 - 8.4e-08 32.2 0.8 8.4e-08 32.2 0.8 2.7 1 1 0 3 3 3 1 Mid2 like cell wall stress sensor Herpes_DNAp_acc PF04929.12 KUM63270.1 - 0.013 14.5 18.0 0.019 13.9 18.0 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Endomucin PF07010.12 KUM63270.1 - 0.015 15.3 42.3 0.017 15.1 42.3 1.0 1 0 0 1 1 1 0 Endomucin Utp14 PF04615.13 KUM63270.1 - 0.47 9.0 5.4 0.53 8.8 5.4 1.0 1 0 0 1 1 1 0 Utp14 protein FeoB_associated PF12669.7 KUM63270.1 - 3.8 8.0 5.2 13 6.3 5.2 1.8 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF2561 PF10812.8 KUM63270.1 - 9 6.3 7.6 45 4.0 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2561) DUF3292 PF11696.8 KUM63274.1 - 6.8e-275 913.5 0.0 7.9e-275 913.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) F_bP_aldolase PF01116.20 KUM63275.1 - 1.3e-92 310.3 0.0 1.4e-92 310.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II UCH PF00443.29 KUM63276.1 - 2.2e-38 132.3 0.0 1.2e-33 116.7 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KUM63276.1 - 2e-08 34.2 3.1 1.4e-06 28.1 3.1 2.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UQ_con PF00179.26 KUM63277.1 - 1.1e-42 145.0 0.0 1.3e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KUM63277.1 - 7.4e-05 22.5 0.0 9.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KUM63277.1 - 0.011 16.1 0.1 0.014 15.7 0.1 1.4 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KUM63277.1 - 0.044 13.6 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain TAL_effector PF03377.13 KUM63278.1 - 0.11 12.8 0.1 19 5.6 0.0 2.3 2 0 0 2 2 2 0 TAL effector repeat CUE PF02845.16 KUM63280.1 - 5.2e-09 35.6 0.0 7.7e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain PRP38_assoc PF12871.7 KUM63280.1 - 6.7 7.4 10.2 0.2 12.3 0.7 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term AlaDh_PNT_N PF05222.15 KUM63281.1 - 6e-30 104.3 0.0 9.6e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KUM63281.1 - 7.3e-05 22.2 0.1 0.0013 18.1 0.1 2.2 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Kinesin PF00225.23 KUM63283.1 - 3.4e-41 141.3 0.0 5e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain bZIP_2 PF07716.15 KUM63283.1 - 0.0017 18.4 3.1 0.0051 16.9 3.1 1.9 1 0 0 1 1 1 1 Basic region leucine zipper EzrA PF06160.12 KUM63283.1 - 0.47 8.6 6.1 1.3 7.1 2.2 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Stathmin PF00836.19 KUM63283.1 - 4.5 7.2 11.4 1.5 8.8 8.0 1.8 1 1 0 1 1 1 0 Stathmin family Med24_N PF11277.8 KUM63284.1 - 0.081 11.0 0.1 0.74 7.8 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 24 N-terminal RTA1 PF04479.13 KUM63285.1 - 4.6e-39 134.2 8.1 6.3e-39 133.7 8.1 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF2754 PF10953.8 KUM63285.1 - 0.12 12.7 2.7 0.65 10.3 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) Kinesin PF00225.23 KUM63286.1 - 3.9e-07 29.3 0.0 4.6e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KUM63286.1 - 3.9e-05 23.6 0.0 4.8e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Microtubule binding FA_hydroxylase PF04116.13 KUM63287.1 - 0.019 15.3 0.3 0.033 14.5 0.3 1.4 1 0 0 1 1 1 0 Fatty acid hydroxylase superfamily DJ-1_PfpI PF01965.24 KUM63288.1 - 9.3e-15 54.8 0.0 1.8e-14 53.9 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family Lactamase_B_2 PF12706.7 KUM63289.1 - 1.5e-13 50.7 0.0 3.1e-13 49.7 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KUM63289.1 - 1.1e-09 38.4 0.0 1.5e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPR_2 PF07719.17 KUM63290.1 - 1.2e-11 43.8 9.3 7.6e-05 22.5 0.0 6.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KUM63290.1 - 3.2e-08 33.0 2.0 0.0083 15.9 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KUM63290.1 - 4.2e-07 29.7 1.2 0.99 9.8 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KUM63290.1 - 5.7e-06 26.9 13.5 1.7 9.4 0.0 6.7 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KUM63290.1 - 9.6e-06 25.8 3.3 1.5 9.1 0.1 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KUM63290.1 - 1.5e-05 25.4 8.7 2 9.5 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KUM63290.1 - 4e-05 23.3 1.3 1.5 9.0 0.0 4.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 KUM63290.1 - 0.00029 21.2 5.2 0.091 13.4 0.1 4.3 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KUM63290.1 - 0.00088 19.1 1.4 1.2 9.1 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KUM63290.1 - 0.0014 18.7 0.1 0.024 14.8 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KUM63290.1 - 0.0055 17.2 4.3 4.5 7.9 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.20 KUM63290.1 - 0.26 11.6 2.6 18 5.9 0.1 4.7 6 0 0 6 6 5 0 PPR repeat Sel1 PF08238.12 KUM63290.1 - 8.5 7.2 7.7 4 8.3 0.5 3.7 3 1 0 3 3 3 0 Sel1 repeat Peptidase_S24 PF00717.23 KUM63291.1 - 0.0061 16.5 0.1 0.0098 15.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like MFS_1 PF07690.16 KUM63292.1 - 9.6e-33 113.6 31.8 9.6e-33 113.6 31.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM63292.1 - 3.2e-11 42.7 26.8 7.2e-11 41.6 26.8 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter NAD_binding_8 PF13450.6 KUM63293.1 - 6.4e-08 32.7 0.0 1.6e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KUM63293.1 - 4e-05 23.1 0.0 6.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KUM63293.1 - 0.0025 17.1 0.2 0.012 14.9 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM63293.1 - 0.0048 16.2 0.2 0.0077 15.5 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KUM63293.1 - 0.0053 16.1 0.0 0.0077 15.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KUM63293.1 - 0.0083 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KUM63293.1 - 0.011 15.1 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KUM63293.1 - 0.047 13.3 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KUM63293.1 - 0.075 12.1 0.1 0.16 11.0 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 KUM63293.1 - 0.087 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 KUM63293.1 - 0.098 11.3 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein ANAPC_CDC26 PF10471.9 KUM63294.1 - 0.0002 22.1 1.4 0.00042 21.1 0.0 2.3 2 1 1 3 3 3 1 Anaphase-promoting complex APC subunit CDC26 Pkinase PF00069.25 KUM63295.1 - 4.1e-65 219.8 0.0 5.8e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM63295.1 - 1.7e-31 109.4 0.0 2.6e-30 105.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KUM63295.1 - 0.00052 19.4 0.0 0.00093 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KUM63295.1 - 0.00087 18.3 0.1 0.0014 17.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KUM63295.1 - 0.0045 16.6 0.2 0.28 10.8 0.0 2.3 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KUM63295.1 - 0.007 16.3 0.0 0.018 15.0 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KUM63295.1 - 0.0088 15.4 0.2 0.051 12.9 0.0 2.1 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KUM63295.1 - 0.042 13.4 0.0 0.094 12.3 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Fungal_trans_2 PF11951.8 KUM63296.1 - 3.7e-32 111.6 0.8 1.3e-31 109.8 0.8 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM63296.1 - 1.9e-06 27.9 8.0 3.2e-06 27.2 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MetOD1 PF18546.1 KUM63297.1 - 0.059 13.3 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 Metanogen output domain 1 TFIIB PF00382.19 KUM63298.1 - 3.9e-32 110.1 0.3 1.9e-16 59.8 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KUM63298.1 - 9.8e-26 90.1 2.6 1.7e-25 89.3 0.0 2.8 4 0 0 4 4 4 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KUM63298.1 - 0.00027 20.4 2.3 0.00072 19.0 2.3 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KUM63298.1 - 0.00059 19.6 0.1 0.97 9.2 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain IBR PF01485.21 KUM63298.1 - 0.15 12.3 0.7 0.3 11.3 0.7 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain NOA36 PF06524.12 KUM63298.1 - 3.4 6.9 6.5 6.2 6.0 6.5 1.4 1 0 0 1 1 1 0 NOA36 protein Apc15p PF05841.11 KUM63301.1 - 4.3e-15 56.6 1.4 5.7e-15 56.2 0.2 1.8 2 0 0 2 2 2 1 Apc15p protein GATase_2 PF00310.21 KUM63302.1 - 1.3e-180 600.6 0.0 1.8e-180 600.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KUM63302.1 - 1.3e-154 514.8 0.0 1.8e-154 514.3 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KUM63302.1 - 1.9e-113 378.6 0.0 5.4e-112 373.8 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KUM63302.1 - 3.2e-86 287.8 1.6 5.2e-86 287.1 1.6 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KUM63302.1 - 1.1e-25 90.5 0.1 8.9e-25 87.5 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KUM63302.1 - 3.2e-21 75.2 0.1 6.5e-21 74.2 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KUM63302.1 - 2.3e-08 34.2 0.1 9.8e-08 32.1 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KUM63302.1 - 6.7e-08 33.0 0.1 0.00033 21.1 0.1 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KUM63302.1 - 2.7e-06 27.0 0.1 4.8e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KUM63302.1 - 8.9e-06 25.5 1.2 0.0047 16.5 0.3 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KUM63302.1 - 1.4e-05 24.4 0.2 0.00026 20.2 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KUM63302.1 - 2e-05 24.0 2.7 0.12 11.6 0.0 3.7 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KUM63302.1 - 2.1e-05 24.1 0.2 4.2e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KUM63302.1 - 5.3e-05 22.1 0.7 0.00011 21.1 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KUM63302.1 - 0.0029 16.9 0.1 0.0058 15.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KUM63302.1 - 0.0031 16.8 0.1 0.74 9.1 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KUM63302.1 - 0.0037 17.7 1.1 3.2 8.3 0.1 2.9 2 0 0 2 2 2 1 Putative NAD(P)-binding FMN_dh PF01070.18 KUM63302.1 - 0.017 14.2 1.2 0.083 11.9 0.9 2.3 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Thi4 PF01946.17 KUM63302.1 - 0.019 14.2 0.4 0.065 12.5 0.1 2.0 2 0 0 2 2 2 0 Thi4 family FMO-like PF00743.19 KUM63302.1 - 0.058 11.8 0.1 2.6 6.3 0.0 2.7 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.12 KUM63302.1 - 0.12 11.4 0.3 0.55 9.2 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein MADF_DNA_bdg PF10545.9 KUM63302.1 - 0.17 12.3 0.4 0.4 11.0 0.4 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like NAD_binding_2 PF03446.15 KUM63302.1 - 0.18 12.0 0.4 0.78 9.9 0.1 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KUM63302.1 - 0.18 11.1 0.4 0.44 9.9 0.0 1.8 2 0 0 2 2 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KUM63302.1 - 0.19 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 KUM63302.1 - 0.3 10.1 5.5 0.033 13.3 0.5 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF3128 PF11326.8 KUM63304.1 - 4.4e-25 87.9 2.3 7.4e-25 87.1 2.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) RNA12 PF10443.9 KUM63305.1 - 3.9e-165 549.9 0.0 9.5e-165 548.6 0.0 1.6 1 1 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 KUM63305.1 - 4.5e-09 36.6 0.0 1.7e-08 34.6 0.0 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 KUM63305.1 - 1.7e-05 24.6 0.0 9.2e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 KUM63305.1 - 0.0017 18.7 0.0 0.0046 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF2487 PF10673.9 KUM63305.1 - 0.0046 17.0 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) p450 PF00067.22 KUM63306.1 - 3.4e-13 49.2 0.0 6.8e-13 48.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 ILVD_EDD PF00920.21 KUM63307.1 - 6.8e-163 543.0 1.1 9.2e-163 542.5 1.1 1.2 1 0 0 1 1 1 1 Dehydratase family Mcl1_mid PF12341.8 KUM63307.1 - 3.1e-101 338.6 0.0 1.8e-100 336.1 0.0 2.0 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 KUM63307.1 - 2.1e-14 53.6 0.0 7e-06 26.3 0.1 6.7 3 1 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KUM63307.1 - 2.1e-14 53.6 1.3 1.6e-05 25.6 0.1 6.9 7 0 0 7 7 7 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KUM63307.1 - 3.7e-07 29.5 0.0 3.4e-06 26.4 0.0 2.0 1 1 1 2 2 2 1 Coatomer WD associated region Cytochrom_D1 PF02239.16 KUM63307.1 - 0.018 13.6 0.3 0.23 10.0 0.1 2.3 1 1 1 2 2 2 0 Cytochrome D1 heme domain DNA_pol_alpha_N PF12254.8 KUM63307.1 - 0.061 13.4 3.7 0.16 12.1 3.7 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Collagen_bind_2 PF12904.7 KUM63307.1 - 0.11 12.5 0.1 0.38 10.8 0.1 1.9 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase Cauli_VI PF01693.16 KUM63308.1 - 4e-36 123.0 6.3 1e-17 64.1 1.4 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 KUM63308.1 - 5.9e-35 120.5 0.0 9.7e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 RNase H Na_H_Exchanger PF00999.21 KUM63309.1 - 1.1e-48 165.9 21.0 1.4e-48 165.6 21.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Sars6 PF12133.8 KUM63309.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.8 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus Ge1_WD40 PF16529.5 KUM63311.1 - 0.00097 18.2 0.0 0.003 16.6 0.0 1.7 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BAR_3 PF16746.5 KUM63311.1 - 0.21 11.2 2.8 19 4.9 0.0 2.6 2 0 0 2 2 2 0 BAR domain of APPL family Cdh1_DBD_1 PF18196.1 KUM63311.1 - 0.63 10.4 3.3 1.1 9.6 0.1 2.9 3 0 0 3 3 3 0 Chromodomain helicase DNA-binding domain 1 BC10 PF06726.12 KUM63312.1 - 2e-15 56.7 9.4 3.1e-15 56.1 9.4 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 zf-C3HC4 PF00097.25 KUM63313.1 - 3.7e-07 29.9 7.7 6.3e-07 29.2 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KUM63313.1 - 3e-06 27.2 3.0 3e-06 27.2 3.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KUM63313.1 - 3.5e-06 26.8 4.8 2.7e-05 23.9 2.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KUM63313.1 - 9.6e-06 25.8 8.1 8.5e-05 22.8 8.5 2.1 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KUM63313.1 - 1.9e-05 24.7 4.8 0.00012 22.2 5.3 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KUM63313.1 - 2.6e-05 24.1 4.8 5.9e-05 23.0 4.7 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KUM63313.1 - 2.9e-05 23.9 6.7 6.2e-05 22.8 6.7 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KUM63313.1 - 0.064 13.1 9.1 0.55 10.1 9.3 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Paramyxo_C PF01692.18 KUM63313.1 - 0.1 12.0 0.6 0.21 10.9 0.6 1.5 1 0 0 1 1 1 0 Paramyxovirus non-structural protein C zf-RING_10 PF16685.5 KUM63313.1 - 0.33 11.1 2.1 0.78 9.9 2.1 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KUM63313.1 - 2 8.3 6.3 7.9 6.3 3.6 2.6 2 1 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.7 KUM63313.1 - 8 6.8 7.3 25 5.2 7.3 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain UCH PF00443.29 KUM63314.1 - 1.2e-47 162.6 0.0 1.9e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KUM63314.1 - 4.3e-11 43.0 0.2 1.4e-06 28.1 0.0 2.5 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase MAP65_ASE1 PF03999.12 KUM63314.1 - 7.3 5.2 12.0 11 4.6 12.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DLH PF01738.18 KUM63315.1 - 4.3e-29 101.6 0.0 5e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KUM63315.1 - 0.005 16.8 0.1 0.19 11.6 0.1 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KUM63315.1 - 0.028 14.1 0.0 0.076 12.7 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 KUM63315.1 - 0.058 13.0 0.0 0.13 11.8 0.0 1.5 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) LIDHydrolase PF10230.9 KUM63315.1 - 0.068 12.7 0.0 0.087 12.4 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase ERG4_ERG24 PF01222.17 KUM63316.1 - 9.8e-142 472.7 21.5 1.1e-141 472.5 21.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family NMO PF03060.15 KUM63317.1 - 2.6e-34 119.1 7.9 2.4e-32 112.6 7.9 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KUM63317.1 - 1.7e-09 37.2 0.4 3e-08 33.1 0.2 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KUM63317.1 - 2.7e-09 36.5 2.6 4.2e-09 35.9 2.6 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KUM63317.1 - 0.0032 16.6 1.5 0.0073 15.5 1.5 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase Bd3614_N PF14442.6 KUM63317.1 - 0.13 12.6 0.4 3 8.2 0.0 2.4 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal FMN_dh PF01070.18 KUM63318.1 - 1.1e-107 360.1 0.0 1.3e-107 359.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KUM63318.1 - 5e-20 71.4 0.0 1.1e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KUM63318.1 - 9.6e-06 24.8 0.5 0.00056 19.0 0.1 2.9 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KUM63318.1 - 4.3e-05 22.8 0.0 7.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KUM63318.1 - 0.022 14.2 0.0 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF202 PF02656.15 KUM63319.1 - 0.0019 18.6 9.0 0.019 15.4 9.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF202) 6PF2K PF01591.18 KUM63320.1 - 6e-71 238.3 0.0 1.4e-50 171.7 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KUM63320.1 - 5.7e-34 117.5 0.1 6.2e-26 91.3 0.0 2.6 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KUM63320.1 - 3.5e-05 24.0 0.0 0.19 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain KTI12 PF08433.10 KUM63320.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF5128 PF17170.4 KUM63320.1 - 0.076 12.2 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 6-bladed beta-propeller DSBA PF01323.20 KUM63321.1 - 5.4e-31 107.9 0.0 1e-29 103.7 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 KUM63321.1 - 0.1 12.6 0.0 2.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain VTC PF09359.10 KUM63322.1 - 2.2e-86 289.7 1.4 2.3e-86 289.6 0.1 1.6 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 KUM63322.1 - 2.2e-13 50.5 4.2 2.4e-13 50.3 2.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KUM63322.1 - 2.3e-10 40.9 13.4 8.2e-05 22.7 0.2 4.3 2 1 1 4 4 4 4 SPX domain Bax1-I PF01027.20 KUM63322.1 - 0.17 11.7 1.0 0.27 11.0 1.0 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 NUDIX PF00293.28 KUM63323.1 - 3.8e-10 39.9 0.0 8.1e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Mod_r PF07200.13 KUM63324.1 - 1.8 8.7 10.4 3.1 7.9 10.4 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein MFS_1 PF07690.16 KUM63325.1 - 2.1e-44 151.9 16.3 2.1e-44 151.9 16.3 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM63325.1 - 1.1e-06 27.8 6.0 2e-06 27.0 6.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_5 PF05631.14 KUM63325.1 - 0.00014 21.0 0.9 0.00014 21.0 0.9 1.7 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 KUM63325.1 - 0.00081 17.9 0.9 0.0012 17.3 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KUM63325.1 - 0.11 11.8 18.4 0.02 14.2 2.8 2.3 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB MT PF12777.7 KUM63325.1 - 0.21 10.6 0.4 0.34 9.9 0.1 1.4 2 0 0 2 2 2 0 Microtubule-binding stalk of dynein motor DUF1129 PF06570.11 KUM63325.1 - 0.51 9.8 3.6 16 5.0 0.1 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1129) Cation_ATPase_C PF00689.21 KUM63325.1 - 6.3 6.5 8.6 0.47 10.1 1.9 2.5 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus MMU163 PF17119.5 KUM63326.1 - 4e-115 383.2 0.2 5.4e-115 382.8 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis dCMP_cyt_deam_1 PF00383.23 KUM63327.1 - 0.00019 21.3 0.1 0.33 10.8 0.1 2.5 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Na_Ca_ex PF01699.24 KUM63328.1 - 1.7e-32 112.5 35.9 1.1e-16 61.2 18.7 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Arm PF00514.23 KUM63329.1 - 9.7e-20 69.9 4.5 3.7e-05 23.6 0.0 8.4 10 0 0 10 10 10 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KUM63329.1 - 0.0001 22.7 0.6 0.89 10.1 0.0 5.9 6 0 0 6 6 6 1 HEAT-like repeat HEAT PF02985.22 KUM63329.1 - 0.00054 20.0 4.0 27 5.4 0.1 7.0 7 1 1 8 8 8 1 HEAT repeat HEAT_2 PF13646.6 KUM63329.1 - 0.099 13.0 6.4 7.5 7.0 0.0 5.5 6 1 1 7 7 7 0 HEAT repeats IFRD PF05004.13 KUM63329.1 - 0.11 11.6 0.1 0.31 10.1 0.1 1.8 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) DUF3361 PF11841.8 KUM63329.1 - 3.3 7.6 5.0 4.8 7.1 0.1 3.5 5 0 0 5 5 5 0 Domain of unknown function (DUF3361) Cyclin PF08613.11 KUM63330.1 - 1.2e-32 113.5 0.2 2.5e-32 112.5 0.2 1.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KUM63330.1 - 0.00018 21.2 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain GST_N_3 PF13417.6 KUM63331.1 - 1.2e-20 73.7 0.2 2e-20 73.0 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KUM63331.1 - 1.3e-19 70.3 0.1 3.2e-19 69.0 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KUM63331.1 - 7.2e-11 42.3 0.1 1.3e-10 41.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KUM63331.1 - 9.3e-09 35.2 0.2 2.7e-08 33.7 0.2 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KUM63331.1 - 0.003 17.7 0.0 0.0095 16.1 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KUM63331.1 - 0.0085 16.3 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KUM63331.1 - 0.017 15.7 0.0 0.033 14.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KUM63331.1 - 0.2 11.9 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Fructosamin_kin PF03881.14 KUM63332.1 - 2.3e-82 276.5 0.0 2.6e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KUM63332.1 - 0.00032 20.7 0.0 0.00064 19.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family CTP_transf_1 PF01148.20 KUM63333.1 - 3.9e-81 272.7 21.0 4.9e-81 272.4 21.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF389 PF04087.14 KUM63333.1 - 0.045 13.8 0.1 5 7.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF389) Cyclin_N PF00134.23 KUM63334.1 - 9.4e-11 41.6 0.0 3.4e-08 33.3 0.0 2.4 2 1 0 2 2 2 2 Cyclin, N-terminal domain DUF3636 PF12331.8 KUM63335.1 - 2e-48 164.0 0.5 3.5e-48 163.2 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 KUM63335.1 - 0.00011 20.9 2.0 0.62 8.5 0.1 3.2 2 1 1 3 3 3 3 DNA damage checkpoint protein Mu-like_Pro PF10123.9 KUM63335.1 - 0.0013 18.4 0.9 0.0013 18.4 0.9 1.6 2 0 0 2 2 2 1 Mu-like prophage I protein Vip3A_N PF12495.8 KUM63335.1 - 0.17 11.8 0.2 0.3 11.0 0.2 1.3 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal GldM_N PF12081.8 KUM63335.1 - 0.39 10.8 5.5 0.89 9.6 5.5 1.5 1 0 0 1 1 1 0 GldM N-terminal domain DUF730 PF05325.11 KUM63335.1 - 2.6 8.1 4.4 1.3 9.1 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF730) TolA_bind_tri PF16331.5 KUM63335.1 - 4.4 7.5 13.0 0.22 11.6 7.0 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation RNase_H2-Ydr279 PF09468.10 KUM63337.1 - 1.8e-39 135.5 0.8 3.9e-39 134.4 0.0 2.0 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KUM63337.1 - 5.4e-20 71.4 0.1 1.5e-19 70.1 0.1 1.8 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain zf-primase PF09329.11 KUM63338.1 - 1.3e-18 66.5 2.2 2.1e-18 65.8 2.2 1.4 1 0 0 1 1 1 1 Primase zinc finger TPP_enzyme_N PF02776.18 KUM63339.1 - 1.2e-55 187.7 0.0 1.7e-54 184.0 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KUM63339.1 - 1.1e-47 161.6 0.0 1.8e-46 157.7 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KUM63339.1 - 2.5e-39 134.2 0.1 4.5e-39 133.3 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain FHA PF00498.26 KUM63340.1 - 5.1e-13 49.2 0.0 1.6e-12 47.6 0.0 1.9 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KUM63340.1 - 0.12 12.7 0.0 2.9 8.3 0.0 2.3 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DnaJ PF00226.31 KUM63341.1 - 2.4e-09 37.2 0.9 4.9e-09 36.2 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain Iron_traffic PF04362.14 KUM63341.1 - 0.18 11.5 0.2 0.38 10.5 0.2 1.4 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking Methyltransf_25 PF13649.6 KUM63342.1 - 7.1e-11 42.7 0.1 2.4e-10 41.0 0.1 2.0 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 KUM63342.1 - 6.9e-10 38.8 0.1 1.5e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KUM63342.1 - 1e-08 35.7 0.0 2.8e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM63342.1 - 2.5e-08 33.9 0.0 5.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KUM63342.1 - 5.8e-07 29.6 0.2 1.3e-06 28.4 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KUM63342.1 - 4.3e-06 26.4 0.2 8.3e-06 25.5 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KUM63342.1 - 3.4e-05 23.7 0.0 7.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KUM63342.1 - 0.00031 20.2 0.1 0.00059 19.3 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 KUM63342.1 - 0.00063 18.8 0.1 0.0016 17.4 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Met_10 PF02475.16 KUM63342.1 - 0.0041 16.9 0.1 0.0072 16.1 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 KUM63342.1 - 0.0051 16.6 0.0 0.0085 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KUM63342.1 - 0.0057 17.4 0.0 0.018 15.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM63342.1 - 0.012 14.9 0.1 0.027 13.8 0.1 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KUM63342.1 - 0.014 16.4 0.1 0.061 14.4 0.0 2.1 2 0 0 2 2 1 0 Methyltransferase domain PRMT5 PF05185.16 KUM63342.1 - 0.028 14.2 1.3 0.49 10.2 1.3 2.3 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase DHR10 PF18595.1 KUM63342.1 - 0.038 14.0 1.0 0.078 13.0 1.0 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain CMAS PF02353.20 KUM63342.1 - 0.041 13.2 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KUM63342.1 - 0.042 13.6 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Lysine methyltransferase Surfac_D-trimer PF09006.11 KUM63342.1 - 0.067 13.1 0.1 1.4 8.9 0.3 2.7 3 0 0 3 3 2 0 Lung surfactant protein D coiled-coil trimerisation Methyltransf_32 PF13679.6 KUM63342.1 - 0.088 12.8 0.1 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Mo25 PF08569.11 KUM63343.1 - 2e-131 438.2 0.2 2.3e-131 438.1 0.2 1.0 1 0 0 1 1 1 1 Mo25-like RabGAP-TBC PF00566.18 KUM63344.1 - 5.8e-33 114.4 0.0 9.2e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ADH_zinc_N_2 PF13602.6 KUM63345.1 - 3.1e-21 76.8 0.0 5.1e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KUM63345.1 - 2e-18 66.6 0.0 4.1e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 KUM63345.1 - 0.0064 16.2 0.4 0.0097 15.7 0.4 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Epimerase PF01370.21 KUM63345.1 - 0.034 13.6 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glu_dehyd_C PF16912.5 KUM63345.1 - 0.092 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus HATPase_c PF02518.26 KUM63346.1 - 1.7e-22 80.1 0.7 5.8e-22 78.3 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KUM63346.1 - 3.2e-20 72.4 0.3 8.9e-20 70.9 0.1 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KUM63346.1 - 1.3e-16 60.4 1.5 4e-16 58.8 0.1 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KUM63346.1 - 1e-10 41.7 2.6 0.0023 18.2 0.2 4.0 3 1 0 3 3 3 3 PAS fold PAS_4 PF08448.10 KUM63346.1 - 3.3e-06 27.3 0.1 6.3e-05 23.2 0.0 2.9 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 KUM63346.1 - 0.00025 21.3 0.1 0.2 11.9 0.0 3.7 3 1 0 3 3 3 1 PAS domain PAS PF00989.25 KUM63346.1 - 0.0024 17.9 0.0 4.2 7.4 0.0 3.3 2 0 0 2 2 2 2 PAS fold LDB19 PF13002.7 KUM63346.1 - 0.029 14.1 0.7 0.068 12.9 0.7 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like MotA_ExbB PF01618.16 KUM63346.1 - 0.049 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family CagA PF03507.13 KUM63346.1 - 0.88 9.5 3.8 0.77 9.7 0.4 2.5 3 0 0 3 3 3 0 CagA exotoxin KxDL PF10241.9 KUM63347.1 - 3.8e-31 107.2 1.4 4.9e-31 106.9 1.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF4407 PF14362.6 KUM63347.1 - 0.036 13.4 1.9 0.042 13.2 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA PF00004.29 KUM63348.1 - 1.8e-53 180.5 0.0 8.5e-39 133.0 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 KUM63348.1 - 2.7e-12 46.3 0.2 6.4e-11 41.9 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_lid_3 PF17862.1 KUM63348.1 - 7e-11 41.8 0.1 1.6e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KUM63348.1 - 1.6e-08 34.9 0.0 0.00025 21.3 0.0 3.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KUM63348.1 - 3.1e-08 34.2 0.2 0.0065 16.9 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 KUM63348.1 - 1.8e-06 28.2 0.0 0.00014 22.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KUM63348.1 - 1.8e-06 27.5 0.1 0.0043 16.5 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KUM63348.1 - 3e-06 27.1 0.1 0.073 12.8 0.1 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KUM63348.1 - 3.8e-06 26.9 0.0 0.0011 19.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KUM63348.1 - 4.4e-06 26.2 0.1 0.038 13.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 KUM63348.1 - 5.3e-06 26.5 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KUM63348.1 - 8.3e-06 26.0 0.0 0.077 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.18 KUM63348.1 - 1.1e-05 25.5 0.0 2.8e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_18 PF13238.6 KUM63348.1 - 1.9e-05 25.2 0.0 0.1 13.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 KUM63348.1 - 5.1e-05 23.3 0.9 16 5.3 0.0 4.2 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KUM63348.1 - 7.9e-05 22.5 0.0 0.018 14.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KUM63348.1 - 0.0008 19.7 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KUM63348.1 - 0.00092 19.6 0.0 0.15 12.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 KUM63348.1 - 0.0011 18.5 0.2 0.043 13.3 0.0 2.8 4 0 0 4 4 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KUM63348.1 - 0.0035 17.1 0.0 0.19 11.5 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein TsaE PF02367.17 KUM63348.1 - 0.0036 17.3 0.0 0.59 10.1 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KUM63348.1 - 0.005 16.2 0.1 0.075 12.4 0.1 2.3 2 0 0 2 2 2 1 KaiC Parvo_NS1 PF01057.17 KUM63348.1 - 0.0065 15.6 0.0 0.9 8.6 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 NACHT PF05729.12 KUM63348.1 - 0.0074 16.2 0.2 6 6.8 0.0 2.9 3 0 0 3 3 2 0 NACHT domain NB-ARC PF00931.22 KUM63348.1 - 0.01 15.1 0.1 1.8 7.7 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 KUM63348.1 - 0.011 15.3 0.7 3 7.4 0.0 2.9 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KUM63348.1 - 0.014 15.9 0.1 0.091 13.3 0.1 2.3 2 0 0 2 2 2 0 ABC transporter AAA_11 PF13086.6 KUM63348.1 - 0.022 14.6 0.0 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KUM63348.1 - 0.03 14.7 0.0 14 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KUM63348.1 - 0.038 13.5 0.0 7.1 6.0 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Sigma54_activat PF00158.26 KUM63348.1 - 0.038 13.7 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 KUM63348.1 - 0.039 13.8 0.0 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KUM63348.1 - 0.043 13.2 0.0 3.8 6.9 0.0 3.1 2 1 1 3 3 3 0 Bacterial TniB protein AAA_19 PF13245.6 KUM63348.1 - 0.045 14.1 0.3 0.68 10.3 0.1 2.7 2 1 0 3 3 3 0 AAA domain PhoH PF02562.16 KUM63348.1 - 0.068 12.6 0.0 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 KUM63348.1 - 0.098 12.4 0.1 0.73 9.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain Cir_N PF10197.9 KUM63349.1 - 0.00012 22.2 4.8 0.00012 22.2 4.8 3.7 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR PP2C PF00481.21 KUM63350.1 - 4.1e-40 138.0 0.0 6.5e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KUM63350.1 - 0.00071 19.3 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C DASH_Duo1 PF08651.10 KUM63352.1 - 8.5e-32 108.8 2.3 1.3e-31 108.2 1.6 1.7 2 0 0 2 2 2 1 DASH complex subunit Duo1 FYRC PF05965.14 KUM63352.1 - 0.023 14.8 0.3 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 F/Y rich C-terminus DUF4047 PF13256.6 KUM63352.1 - 0.1 12.8 1.4 0.19 11.9 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DASH_Dad2 PF08654.10 KUM63352.1 - 0.77 10.2 10.0 0.14 12.6 5.6 2.1 2 1 0 2 2 2 0 DASH complex subunit Dad2 GalKase_gal_bdg PF10509.9 KUM63353.1 - 2.5e-19 68.6 0.0 4.9e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KUM63353.1 - 2.9e-15 56.2 1.4 7.5e-15 54.9 1.4 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KUM63353.1 - 6.1e-13 49.0 0.0 1.6e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal AAA_12 PF13087.6 KUM63355.1 - 7.7e-42 143.2 0.0 1.3e-41 142.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KUM63355.1 - 6.4e-27 95.0 0.2 1.2e-26 94.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KUM63355.1 - 1.4e-09 38.4 0.1 2.8e-08 34.2 0.1 2.8 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KUM63355.1 - 3.6e-06 26.5 0.2 0.031 13.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KUM63355.1 - 3.7e-05 23.5 0.7 0.0025 17.6 0.1 2.6 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 KUM63355.1 - 0.0016 18.1 0.1 0.0057 16.2 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KUM63355.1 - 0.0025 17.6 0.0 0.52 10.0 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KUM63355.1 - 0.034 14.4 0.1 0.51 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KUM63355.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-CCCH_4 PF18044.1 KUM63355.1 - 0.061 13.1 4.1 0.14 12.0 4.1 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger UvrD_C_2 PF13538.6 KUM63355.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain zf-CCCH PF00642.24 KUM63355.1 - 0.53 10.3 3.2 1.2 9.2 3.2 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KUM63355.1 - 0.93 9.6 4.1 4.2 7.5 4.1 2.1 1 1 0 1 1 1 0 Zinc finger domain Zap1_zf2 PF18217.1 KUM63355.1 - 2.1 8.4 4.3 3.5 7.7 1.1 2.5 2 0 0 2 2 2 0 Zap1 zinc finger 2 HRG PF16954.5 KUM63356.1 - 7.9 7.0 13.8 10 6.6 0.6 3.6 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Apolipoprotein PF01442.18 KUM63357.1 - 0.013 15.4 1.3 0.019 14.9 1.3 1.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KUM63357.1 - 0.1 13.2 6.6 2.2 8.9 6.7 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.18 KUM63357.1 - 0.33 11.0 9.2 0.32 11.1 8.3 1.4 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) YtxH PF12732.7 KUM63357.1 - 1.3 9.6 16.9 1.7 9.2 7.2 2.2 1 1 1 2 2 2 0 YtxH-like protein RINGv PF12906.7 KUM63358.1 - 1.3e-05 25.2 5.7 2.5e-05 24.3 5.7 1.5 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 KUM63358.1 - 1.6e-05 25.0 2.4 3.1e-05 24.1 2.4 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KUM63358.1 - 0.051 13.9 4.6 0.098 13.0 4.6 1.5 1 0 0 1 1 1 0 Ring finger domain Aim21 PF11489.8 KUM63359.1 - 1.4e-244 814.3 75.9 1.4e-244 814.3 75.9 2.4 2 0 0 2 2 2 1 Altered inheritance of mitochondria protein 21 Cg6151-P PF10233.9 KUM63360.1 - 2.9e-40 137.1 17.6 3.4e-40 136.9 17.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.10 KUM63360.1 - 0.01 15.9 14.7 0.014 15.4 14.7 1.2 1 0 0 1 1 1 0 COPI associated protein DUF4149 PF13664.6 KUM63360.1 - 0.03 14.7 2.3 0.03 14.7 2.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) CitMHS PF03600.16 KUM63360.1 - 0.82 8.8 9.7 0.9 8.7 9.7 1.1 1 0 0 1 1 1 0 Citrate transporter DHHC PF01529.20 KUM63360.1 - 1.8 8.6 8.5 2.7 8.1 8.5 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF2070 PF09843.9 KUM63360.1 - 4.8 5.4 12.9 5.9 5.1 12.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ank_2 PF12796.7 KUM63361.1 - 3e-19 69.4 0.2 2.9e-10 40.6 0.1 3.1 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KUM63361.1 - 1.5e-14 52.7 0.1 0.003 17.9 0.0 5.8 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 KUM63361.1 - 1.4e-13 50.7 0.6 0.00081 19.6 0.1 4.0 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KUM63361.1 - 1.5e-13 50.9 0.1 7.2e-08 32.8 0.0 4.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KUM63361.1 - 2e-13 50.1 1.0 9.2e-05 22.7 0.0 5.5 7 0 0 7 7 7 3 Ankyrin repeat CUE PF02845.16 KUM63361.1 - 0.13 12.0 0.1 7 6.5 0.0 2.5 2 0 0 2 2 2 0 CUE domain Vps35 PF03635.17 KUM63362.1 - 0 1024.5 0.2 0 1024.3 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RF-1 PF00472.20 KUM63362.1 - 0.18 11.8 1.0 0.6 10.1 1.0 1.9 1 0 0 1 1 1 0 RF-1 domain DUF4746 PF15928.5 KUM63362.1 - 0.25 10.7 6.9 0.41 10.0 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CobT PF06213.12 KUM63362.1 - 0.27 10.6 4.5 0.5 9.7 4.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NST1 PF13945.6 KUM63363.1 - 1.1e-68 231.2 0.1 1.1e-68 231.2 0.1 4.1 3 1 1 4 4 4 1 Salt tolerance down-regulator Ras PF00071.22 KUM63364.1 - 5.8e-45 152.8 0.0 6.8e-45 152.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM63364.1 - 2.2e-19 69.8 0.0 4.8e-19 68.7 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM63364.1 - 4.2e-06 26.3 0.0 6.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KUM63364.1 - 0.015 14.8 0.0 0.029 13.8 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ADH_zinc_N PF00107.26 KUM63364.1 - 0.046 13.7 0.0 13 5.8 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase PduV-EutP PF10662.9 KUM63364.1 - 0.062 13.0 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KUM63364.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MRP-L28 PF09812.9 KUM63365.1 - 8.9e-08 32.4 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DUF2489 PF10675.9 KUM63365.1 - 0.086 12.8 1.2 0.13 12.2 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) MFS_1 PF07690.16 KUM63366.1 - 1.1e-40 139.6 29.4 1.5e-40 139.2 29.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_5_1 PF06946.11 KUM63366.1 - 0.27 11.6 0.1 0.27 11.6 0.1 2.6 3 0 0 3 3 3 0 Bacteriophage A118-like holin, Hol118 FeoB_C PF07664.12 KUM63366.1 - 0.86 9.3 0.0 0.86 9.3 0.0 3.8 4 1 1 5 5 5 0 Ferrous iron transport protein B C terminus Acyl_transf_3 PF01757.22 KUM63366.1 - 6.4 5.7 34.8 0.041 12.9 13.8 2.5 2 1 0 2 2 2 0 Acyltransferase family 3HCDH_N PF02737.18 KUM63367.1 - 2.5e-31 109.0 0.0 4.2e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KUM63367.1 - 9.7e-15 55.0 0.1 1.9e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 KUM63367.1 - 3e-05 24.0 0.1 4.3e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 KUM63367.1 - 0.00018 21.7 0.0 0.00033 20.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KUM63367.1 - 0.0049 17.4 0.6 0.013 16.1 0.5 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 KUM63367.1 - 0.098 12.2 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase RGS PF00615.19 KUM63368.1 - 0.13 12.5 0.0 1.2 9.4 0.0 2.1 1 1 0 1 1 1 0 Regulator of G protein signaling domain RRM_1 PF00076.22 KUM63370.1 - 3.4e-33 113.3 0.1 2.7e-15 55.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KUM63370.1 - 1.7e-10 40.8 0.1 0.00025 21.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KUM63370.1 - 0.0034 17.4 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KUM63370.1 - 0.043 13.9 3.3 1.5 8.9 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif Thi4 PF01946.17 KUM63372.1 - 6.3e-110 366.0 0.0 7.8e-110 365.7 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KUM63372.1 - 2.5e-08 33.9 0.2 1.6e-07 31.3 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KUM63372.1 - 2.2e-05 24.6 0.7 6.3e-05 23.1 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KUM63372.1 - 5.4e-05 22.4 0.4 9.7e-05 21.6 0.4 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KUM63372.1 - 0.00037 20.5 0.2 0.0015 18.6 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KUM63372.1 - 0.00074 18.8 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM63372.1 - 0.0012 18.0 2.2 0.014 14.5 1.5 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KUM63372.1 - 0.0062 15.8 0.1 0.01 15.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KUM63372.1 - 0.041 13.2 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KUM63372.1 - 0.053 12.8 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KUM63372.1 - 0.15 10.9 0.2 0.21 10.4 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 KUM63372.1 - 0.15 10.7 0.2 0.39 9.4 0.5 1.5 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.16 KUM63373.1 - 6.3e-30 104.3 28.5 6.3e-30 104.3 27.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KUM63373.1 - 0.84 8.4 9.0 0.02 13.8 1.1 2.2 3 0 0 3 3 3 0 MFS_1 like family HTH_32 PF13565.6 KUM63374.1 - 1.9e-07 31.6 3.9 0.0015 19.1 0.1 2.5 1 1 2 3 3 3 2 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KUM63374.1 - 0.026 14.8 0.1 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 Transposase Complex1_LYR PF05347.15 KUM63374.1 - 0.087 12.9 0.5 0.21 11.7 0.2 1.8 2 0 0 2 2 2 0 Complex 1 protein (LYR family) TRP PF06011.12 KUM63375.1 - 1.6e-136 455.4 11.9 2.2e-136 455.0 11.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KUM63375.1 - 4.7e-40 137.2 0.2 7.6e-40 136.5 0.2 1.3 1 0 0 1 1 1 1 ML-like domain TMEM154 PF15102.6 KUM63375.1 - 0.00012 22.0 3.8 2.3 8.1 0.1 3.4 3 0 0 3 3 3 2 TMEM154 protein family Shisa PF13908.6 KUM63375.1 - 0.0049 17.1 4.7 0.94 9.7 0.0 2.9 2 1 0 2 2 2 2 Wnt and FGF inhibitory regulator DUF2663 PF10864.8 KUM63375.1 - 0.014 15.8 1.7 0.014 15.8 1.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) DUF3169 PF11368.8 KUM63375.1 - 0.054 13.0 9.3 0.044 13.3 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) ETRAMP PF09716.10 KUM63375.1 - 0.13 12.3 0.0 0.13 12.3 0.0 3.0 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Pox_A28 PF04584.14 KUM63375.1 - 0.54 10.5 2.2 1.1 9.4 1.0 2.3 2 0 0 2 2 2 0 Poxvirus A28 family Exo_endo_phos PF03372.23 KUM63376.1 - 6.3e-15 55.3 0.0 1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Luciferase_cat PF10285.9 KUM63376.1 - 0.14 11.5 0.1 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain WD40 PF00400.32 KUM63377.1 - 4.3e-49 163.4 13.7 1.2e-11 44.9 0.3 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM63377.1 - 3.6e-18 65.7 0.1 0.031 14.6 0.0 6.3 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KUM63377.1 - 2.5e-07 30.8 0.1 0.00037 20.4 0.0 3.1 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KUM63377.1 - 2.7e-07 29.6 5.9 0.072 11.7 0.1 5.1 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KUM63377.1 - 1.9e-05 23.8 0.2 1.3 7.9 0.0 4.4 2 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KUM63377.1 - 0.00036 20.0 0.0 0.012 14.9 0.0 2.7 2 1 1 3 3 3 1 WD40-like domain IKI3 PF04762.12 KUM63377.1 - 0.0017 16.4 0.0 0.0024 15.9 0.0 1.1 1 0 0 1 1 1 1 IKI3 family Nbas_N PF15492.6 KUM63377.1 - 0.064 12.6 0.4 9.2 5.5 0.1 3.0 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal VID27 PF08553.10 KUM63377.1 - 0.097 11.7 0.0 0.24 10.4 0.0 1.7 1 1 0 1 1 1 0 VID27 C-terminal WD40-like domain ADH_zinc_N_2 PF13602.6 KUM63378.1 - 1.9e-18 67.8 0.0 3.1e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KUM63378.1 - 4.5e-10 39.6 0.0 1.9e-09 37.6 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM63378.1 - 4.7e-07 29.7 0.0 1.6e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ABC2_membrane PF01061.24 KUM63379.1 - 3e-61 206.5 48.1 3.3e-31 108.4 19.4 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KUM63379.1 - 1.3e-42 145.6 0.0 1.7e-21 77.1 0.1 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KUM63379.1 - 1.4e-29 101.8 0.3 1.2e-21 76.4 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter RsgA_GTPase PF03193.16 KUM63379.1 - 1.1e-05 25.5 0.2 7.9e-05 22.6 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KUM63379.1 - 3.9e-05 24.1 0.9 0.0015 18.9 0.2 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KUM63379.1 - 9.7e-05 22.2 0.1 0.046 13.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KUM63379.1 - 0.00067 19.2 0.1 0.15 11.5 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 KUM63379.1 - 0.00081 18.6 9.9 0.00081 18.6 9.9 3.3 3 1 1 4 4 4 1 ABC-2 family transporter protein AAA_21 PF13304.6 KUM63379.1 - 0.0035 17.2 1.2 0.62 9.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KUM63379.1 - 0.0047 16.9 2.4 0.71 9.8 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KUM63379.1 - 0.0052 17.1 0.4 1.9 8.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KUM63379.1 - 0.0052 17.3 0.0 0.71 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KUM63379.1 - 0.017 15.2 0.9 0.13 12.4 0.7 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 KUM63379.1 - 0.023 14.5 0.3 1.3 8.8 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 KUM63379.1 - 0.025 14.8 1.9 0.16 12.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KUM63379.1 - 0.034 13.9 0.1 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KUM63379.1 - 0.07 12.9 4.3 0.51 10.1 0.5 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 KUM63379.1 - 0.1 11.6 0.1 7.9 5.4 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein SbcCD_C PF13558.6 KUM63379.1 - 0.15 12.3 0.2 6.2 7.1 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 KUM63379.1 - 0.17 12.1 0.4 0.62 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KUM63379.1 - 0.32 11.4 1.2 4.4 7.8 0.2 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KUM63379.1 - 1 9.0 5.0 3.2 7.3 0.9 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain adh_short PF00106.25 KUM63380.1 - 4.4e-10 39.4 0.0 7.2e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM63380.1 - 0.00029 20.4 0.0 0.00045 19.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM63380.1 - 0.00047 20.1 0.0 0.00075 19.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.18 KUM63381.1 - 8.4e-20 70.9 4.9 1.3e-19 70.3 4.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MAPEG PF01124.18 KUM63381.1 - 0.14 12.1 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 MAPEG family SlyX PF04102.12 KUM63381.1 - 0.93 10.2 3.9 1.6 9.4 0.1 2.6 2 0 0 2 2 2 0 SlyX adh_short_C2 PF13561.6 KUM63382.1 - 3.4e-45 154.4 0.0 4.4e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM63382.1 - 2.9e-31 108.4 0.0 3.8e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM63382.1 - 1.3e-05 25.1 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KUM63382.1 - 0.085 12.0 0.0 1.6 7.9 0.0 2.1 1 1 0 1 1 1 0 Male sterility protein NAD_binding_7 PF13241.6 KUM63382.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding MFS_1 PF07690.16 KUM63383.1 - 4.1e-31 108.2 52.2 2.3e-30 105.7 51.9 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2784 PF10861.8 KUM63383.1 - 0.0066 16.5 0.9 0.0066 16.5 0.9 2.4 1 1 0 1 1 1 1 Protein of Unknown function (DUF2784) Gram_pos_anchor PF00746.21 KUM63383.1 - 0.26 11.3 0.1 0.26 11.3 0.1 2.7 3 0 0 3 3 3 0 LPXTG cell wall anchor motif ADH_zinc_N PF00107.26 KUM63384.1 - 4.1e-16 59.2 0.0 7.2e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM63384.1 - 1e-15 57.6 0.7 1.7e-15 56.8 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 KUM63384.1 - 0.002 17.5 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KUM63384.1 - 0.0032 16.8 0.0 0.0063 15.8 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KUM63384.1 - 0.0036 18.4 0.0 0.0087 17.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 KUM63384.1 - 0.057 13.1 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ETC_C1_NDUFA4 PF04800.12 KUM63384.1 - 0.19 12.0 0.3 0.73 10.1 0.1 1.9 2 0 0 2 2 2 0 ETC complex I subunit conserved region Gp_dh_N PF00044.24 KUM63384.1 - 0.28 11.5 1.0 30 5.0 0.0 2.4 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Amidohydro_2 PF04909.14 KUM63385.1 - 2.9e-39 135.6 1.1 3.3e-39 135.4 1.1 1.0 1 0 0 1 1 1 1 Amidohydrolase OpcA PF07239.11 KUM63385.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein OpcA p450 PF00067.22 KUM63386.1 - 8.7e-45 153.3 0.0 1.5e-28 99.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_43 PF04616.14 KUM63387.1 - 8.2e-38 130.4 3.3 1.1e-37 130.0 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 p450 PF00067.22 KUM63388.1 - 7.3e-75 252.5 0.0 9.3e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RrnaAD PF00398.20 KUM63389.1 - 6.3e-64 215.6 0.0 1.8e-63 214.1 0.0 1.7 1 1 1 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KUM63389.1 - 5.5e-08 33.4 0.0 1.5e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM63389.1 - 2.1e-05 25.1 0.0 5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KUM63389.1 - 3.1e-05 23.8 0.0 5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KUM63389.1 - 0.00045 20.1 0.0 0.00085 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM63389.1 - 0.00054 20.7 0.0 0.0012 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM63389.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KUM63389.1 - 0.0024 17.2 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KUM63389.1 - 0.0053 16.3 0.1 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.20 KUM63389.1 - 0.0075 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PHD_like PF12910.7 KUM63389.1 - 0.083 12.9 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system Methyltransf_28 PF02636.17 KUM63389.1 - 0.099 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 KUM63389.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_18 PF12847.7 KUM63389.1 - 0.13 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PRP1_N PF06424.12 KUM63390.1 - 9.8e-47 159.1 9.4 1.5e-28 100.1 3.4 2.7 2 0 0 2 2 2 2 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 KUM63390.1 - 7.6e-29 100.0 14.1 1.3e-07 32.0 0.3 9.9 6 3 2 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 KUM63390.1 - 9e-28 94.6 35.7 1.3e-05 25.6 0.2 14.0 5 3 9 14 14 13 10 Tetratricopeptide repeat TPR_16 PF13432.6 KUM63390.1 - 1.6e-13 51.0 25.5 0.0017 18.9 0.0 8.2 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 KUM63390.1 - 1.7e-12 46.4 13.4 0.17 12.1 0.0 9.3 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KUM63390.1 - 7.9e-12 44.7 1.2 0.49 10.1 0.0 7.6 7 1 1 8 8 8 3 TPR repeat TPR_8 PF13181.6 KUM63390.1 - 2.5e-08 33.5 0.0 0.83 10.0 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 KUM63390.1 - 4.8e-08 32.5 0.6 0.21 11.5 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KUM63390.1 - 6.2e-07 29.4 4.9 5.3 7.7 0.0 8.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_21 PF09976.9 KUM63390.1 - 3.6e-05 23.5 10.7 0.02 14.6 2.5 4.5 5 1 0 5 5 5 2 Tetratricopeptide repeat-like domain NARP1 PF12569.8 KUM63390.1 - 8.7e-05 21.6 1.2 5.8 5.7 0.0 5.1 3 1 3 6 6 6 1 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 KUM63390.1 - 0.00028 21.1 0.2 0.45 10.8 0.1 4.2 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KUM63390.1 - 0.00067 19.8 6.2 0.48 10.6 0.0 5.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KUM63390.1 - 0.0035 17.8 10.4 7.5 7.5 0.1 6.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KUM63390.1 - 0.0093 15.9 0.8 30 4.9 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KUM63390.1 - 0.015 15.6 8.7 6.7 7.1 0.0 7.4 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 KUM63390.1 - 0.049 14.3 12.6 1.6e+02 3.3 0.0 8.7 9 0 0 9 9 8 0 Tetratricopeptide repeat AdenylateSensor PF16579.5 KUM63390.1 - 0.083 13.3 0.4 25 5.3 0.0 3.8 3 1 1 4 4 4 0 Adenylate sensor of SNF1-like protein kinase ZNRF_3_ecto PF18212.1 KUM63390.1 - 0.087 12.8 0.2 32 4.6 0.0 3.8 4 0 0 4 4 4 0 ZNRF-3 Ectodomain CheZ PF04344.13 KUM63390.1 - 0.16 11.8 0.9 0.59 10.0 0.9 1.9 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ DUF3808 PF10300.9 KUM63390.1 - 0.19 10.4 0.4 35 3.0 0.0 4.0 5 1 0 5 5 5 0 Protein of unknown function (DUF3808) SAGA-Tad1 PF12767.7 KUM63391.1 - 4.8e-54 183.6 0.0 6.3e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit FUSC_2 PF13515.6 KUM63392.1 - 3.5e-30 104.7 10.9 3.5e-30 104.7 10.9 2.7 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KUM63392.1 - 2.6e-06 27.5 0.3 5.5e-06 26.4 0.3 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ALMT PF11744.8 KUM63392.1 - 0.0098 14.8 21.9 0.067 12.0 0.0 3.8 4 1 0 4 4 4 2 Aluminium activated malate transporter Phage_holin_3_1 PF05106.12 KUM63392.1 - 0.034 14.6 1.0 0.17 12.3 1.0 2.3 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) SLATT_fungal PF18142.1 KUM63392.1 - 0.079 12.9 0.6 0.4 10.7 0.6 2.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Phage_holin_Dp1 PF16938.5 KUM63392.1 - 6.8 7.0 8.9 2.6 8.3 0.2 3.5 3 0 0 3 3 3 0 Putative phage holin Dp-1 FUSC PF04632.12 KUM63392.1 - 7 5.1 22.7 5.1 5.5 9.9 4.2 5 0 0 5 5 5 0 Fusaric acid resistance protein family WD40 PF00400.32 KUM63393.1 - 6.9e-24 83.7 30.3 0.0002 22.1 0.1 10.1 10 1 1 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM63393.1 - 1.3e-14 54.3 8.1 0.00012 22.3 0.0 6.9 4 3 4 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KUM63393.1 - 0.068 12.4 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus IRF PF00605.17 KUM63393.1 - 0.069 13.4 1.3 11 6.3 0.1 2.6 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor Ribosomal_S18 PF01084.20 KUM63394.1 - 4e-15 55.8 0.0 6.1e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 ketoacyl-synt PF00109.26 KUM63396.1 - 2.7e-84 282.7 0.1 3.2e-84 282.5 0.1 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 KUM63396.1 - 2.5e-06 27.1 0.3 6.6e-06 25.7 0.2 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ketoacyl-synt_C PF02801.22 KUM63396.1 - 0.0019 18.2 0.2 0.01 15.8 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 KUM63396.1 - 0.8 9.6 3.3 6.8 6.6 3.3 2.2 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.22 KUM63398.1 - 9.1e-09 34.6 1.9 2.6e-06 26.4 0.1 2.1 1 1 1 2 2 2 2 Cytochrome P450 Vhr1 PF04001.13 KUM63398.1 - 0.13 12.6 0.1 0.42 10.9 0.1 1.8 1 1 0 1 1 1 0 Transcription factor Vhr1 Neuropep_like PF15161.6 KUM63399.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Neuropeptide-like Cytochrom_C552 PF02335.15 KUM63399.1 - 0.24 10.3 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c552 Phage_sheath_1 PF04984.14 KUM63400.1 - 0.03 14.2 0.0 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain Goodbye PF17109.5 KUM63401.1 - 1.1e-33 116.2 0.9 4.4e-32 111.1 0.0 2.8 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain TPR_12 PF13424.6 KUM63401.1 - 9.8e-06 25.8 2.5 2 8.8 0.0 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.6 KUM63401.1 - 4.9e-05 23.8 0.2 0.0022 18.4 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KUM63401.1 - 9.6e-05 22.7 0.0 0.0015 18.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain TPR_2 PF07719.17 KUM63401.1 - 0.0009 19.2 8.5 0.92 9.8 0.1 5.4 6 0 0 6 6 4 2 Tetratricopeptide repeat NACHT PF05729.12 KUM63401.1 - 0.0034 17.3 0.0 0.016 15.1 0.0 2.3 1 0 0 1 1 1 1 NACHT domain TPR_1 PF00515.28 KUM63401.1 - 0.004 16.9 0.5 1.5 8.7 0.0 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KUM63401.1 - 0.0063 17.2 3.9 0.66 10.9 0.1 5.0 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KUM63401.1 - 0.0083 16.1 8.5 0.055 13.5 0.1 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat PIF1 PF05970.14 KUM63401.1 - 0.015 14.5 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase DUF2075 PF09848.9 KUM63401.1 - 0.027 13.7 0.0 0.071 12.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhageMin_Tail PF10145.9 KUM63401.1 - 0.034 14.0 0.3 0.034 14.0 0.3 2.3 3 1 0 3 3 2 0 Phage-related minor tail protein TPR_8 PF13181.6 KUM63401.1 - 0.04 14.1 4.9 8.4 6.9 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 KUM63401.1 - 0.043 13.5 0.1 0.65 9.7 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein Bac_GH3_C PF18034.1 KUM63401.1 - 0.045 13.5 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain TPR_19 PF14559.6 KUM63401.1 - 0.047 14.2 0.9 0.25 11.9 0.0 2.8 2 0 0 2 2 1 0 Tetratricopeptide repeat DUF4201 PF13870.6 KUM63401.1 - 0.064 13.0 1.4 0.094 12.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TPR_10 PF13374.6 KUM63401.1 - 0.073 13.0 4.6 14 5.7 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KUM63401.1 - 0.1 13.0 0.9 0.42 11.1 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KUM63401.1 - 0.12 12.1 0.1 0.38 10.5 0.1 1.8 1 0 0 1 1 1 0 TPR repeat DUF948 PF06103.11 KUM63401.1 - 6.8 7.0 5.6 2.4 8.5 1.7 2.3 3 0 0 3 3 1 0 Bacterial protein of unknown function (DUF948) Fungal_trans_2 PF11951.8 KUM63402.1 - 1.2e-12 47.4 2.6 1.8e-12 46.8 2.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PPR_2 PF13041.6 KUM63403.1 - 2.4e-08 34.0 0.4 4.4 7.6 0.0 7.4 8 0 0 8 8 8 2 PPR repeat family PPR PF01535.20 KUM63403.1 - 1.2e-05 25.2 2.5 2.4 8.6 0.1 6.6 6 0 0 6 6 6 1 PPR repeat PPR_long PF17177.4 KUM63403.1 - 0.00085 18.7 1.4 0.17 11.2 0.1 3.7 3 1 1 4 4 4 1 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 KUM63403.1 - 0.046 14.2 5.3 2.3 8.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Mycoplasma_p37 PF06646.11 KUM63403.1 - 0.15 11.3 0.1 0.24 10.6 0.1 1.2 1 0 0 1 1 1 0 High affinity transport system protein p37 CorA PF01544.18 KUM63404.1 - 4.4e-06 26.2 0.0 8.2e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RabGAP-TBC PF00566.18 KUM63405.1 - 3.8e-50 170.5 0.0 8.6e-50 169.4 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain CENP-B_dimeris PF09026.10 KUM63405.1 - 4.1 7.8 9.0 7.8 7.0 9.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Glyco_transf_24 PF18404.1 KUM63406.1 - 1.2e-146 487.2 1.2 1.8e-146 486.6 1.2 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KUM63406.1 - 3.8e-67 226.9 0.0 1.4e-64 218.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KUM63406.1 - 3e-49 167.5 0.1 7.2e-49 166.3 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KUM63406.1 - 1.9e-45 155.4 0.1 3.7e-44 151.2 0.4 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KUM63406.1 - 8.9e-44 148.7 3.5 2.3e-43 147.4 0.1 3.1 4 0 0 4 4 4 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KUM63406.1 - 2.3e-42 143.5 0.0 7.2e-42 141.9 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 KUM63406.1 - 0.00095 18.8 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Myb_DNA-binding PF00249.31 KUM63407.1 - 2.3e-16 59.7 9.6 9.5e-08 32.1 0.6 3.2 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KUM63407.1 - 5.6e-16 58.5 5.9 3.7e-11 43.1 1.8 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KUM63407.1 - 0.021 15.0 2.2 0.69 10.1 0.1 2.5 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 SUR7 PF06687.12 KUM63408.1 - 5.1e-41 140.6 8.9 5.9e-41 140.4 8.9 1.0 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.12 KUM63408.1 - 0.0064 16.0 2.7 0.0099 15.4 2.7 1.4 1 0 0 1 1 1 1 Clc-like Amastin PF07344.11 KUM63408.1 - 0.011 15.6 7.9 0.011 15.6 7.9 1.6 2 0 0 2 2 2 0 Amastin surface glycoprotein DUF4491 PF14898.6 KUM63408.1 - 2.4 8.7 5.6 7.9 7.0 1.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4491) HSP70 PF00012.20 KUM63409.1 - 2.8e-81 273.5 1.4 2.8e-81 273.5 1.4 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KUM63409.1 - 2.7e-09 36.3 0.1 4.1e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Peripla_BP_6 PF13458.6 KUM63409.1 - 0.0038 16.9 0.1 0.0076 15.9 0.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein DASH_Spc19 PF08287.11 KUM63410.1 - 2.9e-52 176.7 2.7 4e-52 176.3 2.7 1.2 1 0 0 1 1 1 1 Spc19 Mur_ligase_M PF08245.12 KUM63410.1 - 0.027 14.5 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Mur ligase middle domain Raptor_N PF14538.6 KUM63412.1 - 3.1e-64 215.4 0.0 5.4e-64 214.6 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KUM63412.1 - 4.8e-05 24.0 11.0 0.83 10.6 0.1 6.6 5 1 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 KUM63412.1 - 0.006 16.6 0.1 6.1 6.9 0.1 2.8 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.22 KUM63412.1 - 0.13 12.6 1.3 29 5.3 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat Kelch_3 PF13415.6 KUM63413.1 - 6e-33 112.5 7.8 3.5e-06 27.1 0.1 6.2 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KUM63413.1 - 1.4e-30 105.0 10.0 7.2e-06 25.9 1.4 6.7 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KUM63413.1 - 1.2e-27 95.4 5.9 3.1e-05 23.8 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 KUM63413.1 - 5.2e-26 90.0 1.3 4.7e-09 35.7 0.2 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KUM63413.1 - 6.2e-24 83.4 6.2 3.9e-07 30.1 0.5 6.3 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KUM63413.1 - 4.1e-18 64.6 9.6 3e-06 27.0 0.3 6.4 6 0 0 6 6 6 4 Kelch motif RAG2 PF03089.14 KUM63413.1 - 0.13 11.2 0.0 1.2 8.0 0.0 2.6 4 0 0 4 4 4 0 Recombination activating protein 2 STE3 PF02076.15 KUM63415.1 - 0.054 12.7 0.4 0.084 12.1 0.3 1.4 1 1 1 2 2 2 0 Pheromone A receptor MAP65_ASE1 PF03999.12 KUM63415.1 - 0.34 9.5 9.2 0.4 9.3 9.2 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) LRR_8 PF13855.6 KUM63416.1 - 1.3e-10 40.9 10.1 2.7e-09 36.7 7.9 2.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KUM63416.1 - 2.9e-08 33.9 14.1 5.6e-07 29.8 3.9 3.0 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KUM63416.1 - 0.0028 17.2 0.8 0.0048 16.4 0.8 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KUM63416.1 - 0.026 15.0 4.8 4.8 8.1 0.3 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_5 PF13306.6 KUM63416.1 - 0.099 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KUM63416.1 - 0.87 9.8 2.3 51 4.3 0.8 3.1 3 0 0 3 3 3 0 Leucine Rich repeat adh_short PF00106.25 KUM63417.1 - 1e-41 142.5 0.0 1.6e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM63417.1 - 3e-30 105.5 0.0 3.8e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM63417.1 - 3.4e-15 56.4 0.1 4.8e-15 55.9 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM63417.1 - 3.9e-05 23.2 0.0 0.00016 21.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KUM63417.1 - 8.4e-05 21.8 0.0 0.00012 21.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KUM63417.1 - 0.0031 17.4 0.1 0.0055 16.6 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 KUM63417.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.13 KUM63417.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family zf-RING_2 PF13639.6 KUM63418.1 - 7.9e-13 48.5 5.8 1.3e-12 47.8 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KUM63418.1 - 5.7e-09 35.6 3.0 5.7e-09 35.6 3.0 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KUM63418.1 - 7.9e-09 35.7 2.5 1.7e-08 34.6 2.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KUM63418.1 - 2e-08 33.9 4.5 3.4e-08 33.2 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM63418.1 - 3.2e-08 33.3 3.9 5.3e-08 32.6 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KUM63418.1 - 6.5e-08 32.5 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 KUM63418.1 - 3e-07 30.3 2.9 5e-07 29.6 2.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KUM63418.1 - 9.7e-06 25.4 3.2 1.5e-05 24.8 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KUM63418.1 - 8.3e-05 22.5 3.2 0.00055 19.9 3.2 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KUM63418.1 - 0.00087 19.3 1.2 0.0016 18.4 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KUM63418.1 - 0.0047 16.8 2.9 0.0084 15.9 2.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KUM63418.1 - 0.031 14.4 2.9 0.073 13.2 2.9 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KUM63418.1 - 0.12 12.6 2.7 0.31 11.2 2.7 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KUM63418.1 - 0.43 10.4 3.1 0.81 9.5 3.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KUM63418.1 - 0.45 10.9 3.5 1 9.7 3.5 1.6 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 KUM63418.1 - 0.53 10.2 2.8 0.67 9.9 1.9 1.7 1 1 0 1 1 1 0 PHD-finger RINGv PF12906.7 KUM63418.1 - 0.62 10.2 4.2 1.3 9.2 4.2 1.6 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KUM63418.1 - 1.3 8.7 6.2 0.77 9.4 3.9 1.7 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type mono-CXXC PF15626.6 KUM63418.1 - 1.9 8.9 6.2 1.5 9.2 0.2 3.8 2 0 0 2 2 2 0 single CXXC unit Pkinase PF00069.25 KUM63419.1 - 4.5e-26 91.8 0.0 5.9e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM63419.1 - 6.1e-14 51.9 0.0 8.6e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KUM63419.1 - 4.4e-09 35.6 0.0 6.4e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KUM63419.1 - 0.0002 21.4 0.0 0.0015 18.5 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Vma12 PF11712.8 KUM63422.1 - 1.7e-36 125.3 0.0 2.3e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Adaptin_N PF01602.20 KUM63423.1 - 2.5e-111 372.8 0.1 3.2e-111 372.5 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KUM63423.1 - 2.4e-57 193.3 1.6 5.4e-57 192.2 1.6 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KUM63423.1 - 6.4e-34 116.5 0.4 2.7e-33 114.5 0.1 2.3 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KUM63423.1 - 1.2e-17 64.1 0.2 4.1e-11 43.1 0.0 5.4 4 1 2 6 6 6 3 HEAT repeats Cnd1 PF12717.7 KUM63423.1 - 1.8e-09 37.8 6.3 0.0015 18.6 0.1 5.0 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KUM63423.1 - 0.00011 22.1 4.2 0.27 11.6 0.1 5.8 6 0 0 6 6 6 1 HEAT repeat HEAT_PBS PF03130.16 KUM63423.1 - 0.0032 18.0 1.8 14 6.7 0.0 5.2 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 KUM63423.1 - 0.0098 16.4 0.7 0.049 14.2 0.2 2.5 2 0 0 2 2 2 1 HEAT-like repeat F-box-like PF12937.7 KUM63424.1 - 2e-06 27.6 0.4 5.6e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 F-box-like PX PF00787.24 KUM63425.1 - 1.2e-14 54.2 0.0 1.3e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 PX domain SIP1 PF04938.12 KUM63426.1 - 1.9e-12 47.4 0.1 1.2e-09 38.3 0.0 2.9 2 1 1 3 3 3 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) SDA1 PF05285.12 KUM63426.1 - 0.11 11.9 18.0 0.16 11.3 18.0 1.2 1 0 0 1 1 1 0 SDA1 Plasmodium_Vir PF05795.11 KUM63426.1 - 0.18 11.2 7.2 0.3 10.5 7.2 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DDE_3 PF13358.6 KUM63427.1 - 2.5e-27 95.4 0.1 1.7e-26 92.7 0.0 2.1 2 1 1 3 3 3 1 DDE superfamily endonuclease DDE_1 PF03184.19 KUM63427.1 - 2.3e-06 27.4 0.0 3.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 KUM63427.1 - 3.1e-05 24.2 0.0 9.5e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain HTH_33 PF13592.6 KUM63427.1 - 0.00079 19.0 0.1 0.0022 17.6 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix GCP_C_terminal PF04130.13 KUM63427.1 - 0.033 13.6 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal HTH_32 PF13565.6 KUM63427.1 - 0.12 13.0 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain bZIP_1 PF00170.21 KUM63428.1 - 5.4e-10 39.2 7.6 1e-09 38.3 7.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KUM63428.1 - 3.3e-05 23.9 11.7 3.3e-05 23.9 11.7 1.7 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KUM63428.1 - 0.002 18.6 7.0 0.0031 18.0 7.0 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor PAP1 PF08601.10 KUM63428.1 - 0.0022 17.8 12.9 0.065 13.0 0.0 2.1 2 0 0 2 2 2 1 Transcription factor PAP1 MIS13 PF08202.11 KUM63428.1 - 0.0039 16.5 2.3 0.0053 16.1 2.3 1.1 1 0 0 1 1 1 1 Mis12-Mtw1 protein family HOOK PF05622.12 KUM63428.1 - 0.0044 15.3 3.8 0.0057 14.9 3.8 1.0 1 0 0 1 1 1 1 HOOK protein SHE3 PF17078.5 KUM63428.1 - 0.0057 16.4 3.4 0.0081 15.9 3.4 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 V_ATPase_I PF01496.19 KUM63428.1 - 0.0079 14.2 1.9 0.01 13.8 1.9 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ZapB PF06005.12 KUM63428.1 - 0.01 16.2 2.8 0.01 16.2 2.8 1.9 1 1 1 2 2 2 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 KUM63428.1 - 0.023 14.9 4.9 0.044 14.0 4.9 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 KUM63428.1 - 0.065 13.9 1.5 0.097 13.3 1.1 1.5 1 1 0 1 1 1 0 Initiation control protein YabA PSI_PsaF PF02507.15 KUM63428.1 - 0.078 12.8 1.1 0.14 12.0 1.1 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III DUF1059 PF06348.11 KUM63428.1 - 0.081 13.2 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) FlaC_arch PF05377.11 KUM63428.1 - 0.18 12.2 0.2 0.31 11.5 0.2 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF5595 PF18077.1 KUM63428.1 - 0.2 11.8 1.7 0.33 11.1 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) GvpL_GvpF PF06386.11 KUM63428.1 - 0.22 11.4 4.6 0.33 10.9 4.6 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DivIC PF04977.15 KUM63428.1 - 0.51 10.1 3.9 0.96 9.3 3.9 1.5 1 0 0 1 1 1 0 Septum formation initiator NRBF2 PF08961.10 KUM63428.1 - 0.61 9.6 6.7 1 8.9 6.1 1.5 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator UPF0242 PF06785.11 KUM63428.1 - 0.68 10.0 4.6 1 9.4 4.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5094 PF17015.5 KUM63428.1 - 0.69 10.0 5.3 0.97 9.5 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) TMCO5 PF14992.6 KUM63428.1 - 0.88 9.1 4.3 1.2 8.6 4.3 1.1 1 0 0 1 1 1 0 TMCO5 family Phosducin PF02114.16 KUM63429.1 - 3.9e-10 39.1 0.2 4.9e-10 38.8 0.2 1.2 1 0 0 1 1 1 1 Phosducin Glyco_hydro_72 PF03198.14 KUM63430.1 - 1.6e-135 451.4 5.9 2e-135 451.1 5.9 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KUM63430.1 - 1.2e-06 28.2 0.2 7.8e-06 25.5 0.2 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KUM63430.1 - 0.00041 19.6 1.3 0.0012 18.0 1.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain tRNA-synt_2 PF00152.20 KUM63431.1 - 3.3e-70 236.6 0.1 4.4e-70 236.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KUM63431.1 - 3.3e-06 27.0 0.1 6.2e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Hydrolase_6 PF13344.6 KUM63432.1 - 2.5e-25 88.5 0.0 5.2e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KUM63432.1 - 4.8e-17 61.8 0.0 1.6e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KUM63432.1 - 8.5e-06 26.2 0.0 0.031 14.6 0.1 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KUM63432.1 - 0.013 15.6 0.0 3 7.9 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KUM63432.1 - 0.11 12.8 0.0 4.1 7.8 0.0 2.8 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 KUM63433.1 - 1.2e-14 54.4 0.4 1.6e-13 50.6 0.4 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM63433.1 - 1.5e-06 27.7 0.2 2.3e-06 27.1 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KUM63433.1 - 0.044 13.1 0.1 0.059 12.7 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KUM63433.1 - 0.11 12.1 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 RIO1 family ABC_tran PF00005.27 KUM63434.1 - 4.5e-35 121.1 0.0 9.9e-35 120.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KUM63434.1 - 3e-21 76.3 4.6 3e-21 76.3 4.6 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KUM63434.1 - 3.5e-08 33.1 0.0 6.9e-06 25.7 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KUM63434.1 - 0.0034 17.1 0.4 0.0054 16.5 0.0 1.5 2 0 0 2 2 1 1 AAA ATPase domain AAA_16 PF13191.6 KUM63434.1 - 0.0038 17.6 0.1 0.01 16.3 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KUM63434.1 - 0.008 15.5 0.8 0.042 13.1 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 KUM63434.1 - 0.0081 16.7 0.0 0.0081 16.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KUM63434.1 - 0.015 15.6 0.1 0.041 14.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KUM63434.1 - 0.024 14.4 0.1 0.062 13.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KUM63434.1 - 0.026 15.0 0.0 0.22 12.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KUM63434.1 - 0.03 13.5 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_21 PF13304.6 KUM63434.1 - 0.035 13.9 0.1 0.1 12.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KUM63434.1 - 0.046 13.8 0.7 0.11 12.5 0.1 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain G-alpha PF00503.20 KUM63434.1 - 0.066 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit AAA_18 PF13238.6 KUM63434.1 - 0.092 13.3 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KUM63434.1 - 0.097 12.4 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Herpes_gE PF02480.16 KUM63434.1 - 0.15 10.8 1.0 0.28 9.9 0.0 1.8 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E AAA_14 PF13173.6 KUM63434.1 - 0.16 12.0 0.1 2.3 8.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF5427 PF10310.9 KUM63434.1 - 0.28 10.1 2.2 0.46 9.4 2.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) EphA2_TM PF14575.6 KUM63434.1 - 0.28 12.1 1.5 7.2 7.6 0.0 3.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF1117 PF06547.12 KUM63435.1 - 0.35 11.4 5.0 0.13 12.8 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) KH_6 PF15985.5 KUM63436.1 - 1.6e-16 60.3 0.1 4.3e-16 59.0 0.0 1.8 2 0 0 2 2 2 1 KH domain Rrp40_N PF18311.1 KUM63436.1 - 5.5e-10 39.0 0.6 1.7e-09 37.5 0.6 1.9 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain DUF261 PF03196.13 KUM63436.1 - 0.2 11.7 0.0 0.32 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF261 FHA PF00498.26 KUM63438.1 - 3.5e-16 59.3 0.0 7.1e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KUM63438.1 - 0.001 19.4 0.0 0.0029 17.9 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 KUM63438.1 - 0.0079 15.8 0.4 0.018 14.6 0.0 1.7 2 0 0 2 2 2 1 YhfZ C-terminal domain DUF3482 PF11981.8 KUM63438.1 - 0.17 11.2 3.9 0.46 9.8 3.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Cbl_N PF02262.16 KUM63438.1 - 0.3 11.1 2.4 9.4 6.3 0.1 2.4 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 DUF3080 PF11279.8 KUM63438.1 - 0.37 10.0 8.1 0.077 12.2 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3080) DUF2408 PF10303.9 KUM63438.1 - 1.1 9.8 10.0 0.064 13.8 1.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) LMP PF04778.12 KUM63438.1 - 1.7 8.6 9.7 0.076 12.9 2.1 2.5 3 0 0 3 3 3 0 LMP repeated region Spectrin PF00435.21 KUM63438.1 - 3.5 8.2 13.4 4.4 7.8 3.1 2.9 3 0 0 3 3 3 0 Spectrin repeat DUF2203 PF09969.9 KUM63438.1 - 4.1 8.2 12.4 6.5 7.5 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF812 PF05667.11 KUM63438.1 - 5.9 5.7 24.4 0.034 13.1 15.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF1366 PF07104.11 KUM63438.1 - 6 6.6 11.3 20 4.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1366) NES_C_h PF18208.1 KUM63438.1 - 6.1 7.2 7.5 0.62 10.4 0.2 2.5 2 0 0 2 2 2 0 Nicking enzyme C-terminal middle helical domain Spc7 PF08317.11 KUM63438.1 - 8.6 5.1 21.9 1.3 7.9 5.6 3.1 3 0 0 3 3 3 0 Spc7 kinetochore protein Rpp20 PF12328.8 KUM63439.1 - 1.1e-48 164.7 16.6 3.3e-48 163.1 16.6 1.7 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KUM63439.1 - 3.5e-19 68.4 1.1 5.8e-19 67.7 1.1 1.4 1 0 0 1 1 1 1 Alba FYDLN_acid PF09538.10 KUM63439.1 - 0.0018 18.9 8.6 0.6 10.8 5.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (FYDLN_acid) Presenilin PF01080.17 KUM63439.1 - 0.29 9.8 6.0 0.38 9.5 6.0 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 KUM63439.1 - 2.3 7.9 4.9 1.1 9.0 1.1 1.9 2 0 0 2 2 2 0 Connexin Romo1 PF10247.9 KUM63440.1 - 3.9e-28 97.6 16.2 5e-28 97.3 16.2 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KUM63440.1 - 0.00028 21.2 2.6 0.00034 21.0 2.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TMEM141 PF15110.6 KUM63440.1 - 2.1 9.0 4.5 3.1 8.5 0.8 2.1 1 1 1 2 2 2 0 TMEM141 protein family Rsm22 PF09243.10 KUM63441.1 - 3.8e-32 111.7 0.0 4.1e-30 105.0 0.0 2.7 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Peptidase_M3_N PF08439.10 KUM63441.1 - 0.082 13.2 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 Oligopeptidase F Methyltransf_12 PF08242.12 KUM63441.1 - 0.13 13.0 0.0 0.33 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Rogdi_lz PF10259.9 KUM63442.1 - 1.1e-82 277.5 0.1 1.5e-82 277.1 0.1 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein APP_N PF02177.16 KUM63442.1 - 0.053 13.9 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding Ribosomal_S14 PF00253.21 KUM63443.1 - 5e-22 77.4 1.6 3.8e-21 74.6 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein S14p/S29e Amidohydro_1 PF01979.20 KUM63444.1 - 6.9e-28 97.9 0.0 2e-27 96.5 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KUM63444.1 - 6.1e-13 49.1 0.1 9.9e-08 31.9 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Methyltransf_2 PF00891.18 KUM63445.1 - 5.9e-27 94.3 0.1 1.4e-26 93.1 0.1 1.5 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KUM63445.1 - 7.3e-05 22.7 0.0 0.00037 20.4 0.0 2.0 2 0 0 2 2 2 1 Dimerisation domain Dimerisation PF08100.11 KUM63445.1 - 0.0048 16.9 0.2 0.02 14.9 0.1 2.2 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_25 PF13649.6 KUM63445.1 - 0.028 15.1 0.0 0.082 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain CENP-F_leu_zip PF10473.9 KUM63446.1 - 3e-06 27.3 36.2 0.032 14.3 10.6 5.5 3 2 0 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MAD PF05557.13 KUM63446.1 - 3.2e-05 22.5 10.9 3.2e-05 22.5 10.9 2.8 2 1 1 3 3 3 1 Mitotic checkpoint protein ADIP PF11559.8 KUM63446.1 - 0.0069 16.5 4.7 0.0069 16.5 4.7 4.8 3 1 3 6 6 6 2 Afadin- and alpha -actinin-Binding Sec3_C_2 PF15278.6 KUM63446.1 - 0.041 14.2 0.5 0.18 12.1 0.1 2.4 2 0 0 2 2 2 0 Sec3 exocyst complex subunit Transposase_1 PF01359.18 KUM63446.1 - 0.14 12.0 0.3 0.42 10.5 0.1 1.9 2 0 0 2 2 2 0 Transposase (partial DDE domain) Suppressor_APC PF11414.8 KUM63446.1 - 0.29 11.2 11.5 1.4 9.0 0.5 4.4 3 0 0 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein DUF1943 PF09172.11 KUM63446.1 - 0.33 10.1 2.2 0.53 9.5 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) KLRAQ PF10205.9 KUM63446.1 - 0.65 10.3 21.9 0.22 11.8 6.5 4.1 2 1 3 5 5 5 0 Predicted coiled-coil domain-containing protein GIT_CC PF16559.5 KUM63446.1 - 1.2 9.1 8.8 17 5.3 0.2 4.7 4 1 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Tup_N PF08581.10 KUM63446.1 - 2.2 8.7 22.4 0.78 10.1 0.9 4.7 5 1 0 5 5 4 0 Tup N-terminal Nup54_57_C PF18570.1 KUM63446.1 - 4.3 7.0 4.9 1.2 8.8 0.2 2.6 3 0 0 3 3 3 0 NUP57/Nup54 C-terminal domain FliD_N PF02465.18 KUM63446.1 - 8.5 7.1 12.9 1.5 9.6 0.3 4.3 4 1 1 5 5 5 0 Flagellar hook-associated protein 2 N-terminus DUF724 PF05266.14 KUM63446.1 - 8.8 6.1 21.3 0.25 11.2 9.9 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF724) FAD_binding_3 PF01494.19 KUM63447.1 - 9.8e-14 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Peptidase_M24 PF00557.24 KUM63448.1 - 2.2e-48 164.7 0.0 2.7e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KUM63448.1 - 4.2e-19 68.6 7.9 1e-18 67.3 7.9 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KUM63448.1 - 0.00098 19.2 5.2 0.00098 19.2 5.2 2.3 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 KUM63448.1 - 1.3 8.9 4.2 3.2 7.7 4.2 1.7 1 0 0 1 1 1 0 HIT zinc finger WD40 PF00400.32 KUM63449.1 - 3.3e-33 113.2 9.6 2.7e-08 34.3 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM63449.1 - 1.4e-15 57.4 0.0 1.4e-05 25.3 0.0 5.0 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain MMR_HSR1 PF01926.23 KUM63450.1 - 1.9e-10 40.8 0.0 6.8e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-C2H2_2 PF12756.7 KUM63450.1 - 9.2e-10 38.8 7.2 0.0029 17.9 0.1 3.7 1 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) RsgA_GTPase PF03193.16 KUM63450.1 - 6.6e-05 22.9 1.1 0.0002 21.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase zf-C2H2_4 PF13894.6 KUM63450.1 - 0.00037 21.1 3.6 5.1 8.2 0.4 4.2 4 0 0 4 4 4 1 C2H2-type zinc finger MnmE_helical PF12631.7 KUM63450.1 - 0.0011 19.2 1.7 0.0043 17.3 2.3 1.7 2 0 0 2 2 2 1 MnmE helical domain Dynamin_N PF00350.23 KUM63450.1 - 0.0013 18.9 0.2 0.014 15.4 0.1 4.2 2 2 1 3 3 2 2 Dynamin family AIG1 PF04548.16 KUM63450.1 - 0.0014 18.0 0.0 0.0014 18.0 0.0 2.4 2 1 0 2 2 1 1 AIG1 family IIGP PF05049.13 KUM63450.1 - 0.0092 15.1 2.1 0.019 14.1 0.0 2.1 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) DUF445 PF04286.12 KUM63450.1 - 0.013 15.3 9.2 0.016 15.0 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) zf-C2H2_3rep PF18868.1 KUM63450.1 - 0.015 15.9 8.4 13 6.5 0.0 4.4 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats DUF5487 PF17589.2 KUM63450.1 - 0.033 14.4 0.1 9 6.6 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5487) NB-ARC PF00931.22 KUM63450.1 - 0.067 12.4 0.0 0.067 12.4 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 KUM63450.1 - 0.071 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KUM63450.1 - 0.094 13.3 0.0 0.094 13.3 0.0 3.1 2 1 0 2 2 1 0 AAA domain ABC_tran PF00005.27 KUM63450.1 - 0.13 12.8 0.0 0.13 12.8 0.0 2.9 2 1 0 2 2 1 0 ABC transporter zf-met PF12874.7 KUM63450.1 - 0.16 12.4 1.2 0.47 10.9 0.3 2.3 3 0 0 3 3 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KUM63450.1 - 0.18 12.3 6.7 1.9 9.1 0.9 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF4996 PF16387.5 KUM63450.1 - 0.18 12.3 2.3 0.26 11.8 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF2256 PF10013.9 KUM63450.1 - 0.37 10.9 1.3 41 4.4 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-LYAR PF08790.11 KUM63450.1 - 0.44 10.5 5.5 5.2 7.1 0.1 3.5 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger AAA_23 PF13476.6 KUM63450.1 - 0.56 10.7 0.0 0.56 10.7 0.0 2.9 2 1 0 2 2 1 0 AAA domain PvlArgDC PF01862.16 KUM63450.1 - 0.93 9.3 5.0 7.1 6.4 5.0 2.2 1 1 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Asp-B-Hydro_N PF05279.11 KUM63450.1 - 1.1 9.3 21.8 1.6 8.7 21.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AAA_22 PF13401.6 KUM63450.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.8 2 1 1 3 3 3 0 AAA domain Prok-RING_1 PF14446.6 KUM63450.1 - 1.2 9.1 3.8 83 3.2 0.2 3.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2H2_jaz PF12171.8 KUM63450.1 - 3.2 8.1 6.4 3.8 7.9 0.7 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding XPA_N PF01286.18 KUM63450.1 - 3.4 7.8 8.0 50 4.1 0.5 3.6 3 0 0 3 3 3 0 XPA protein N-terminal Exonuc_VII_L PF02601.15 KUM63450.1 - 4.3 6.8 20.4 5.9 6.4 20.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Vps39_2 PF10367.9 KUM63450.1 - 4.6 7.7 9.0 1.1 9.7 4.9 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 OmpH PF03938.14 KUM63450.1 - 4.8 7.5 42.4 0.37 11.1 27.3 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ZZ PF00569.17 KUM63451.1 - 4.9e-12 45.5 4.2 8.3e-12 44.7 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 KUM63451.1 - 1.5e-11 43.0 4.1 5.5e-05 22.4 0.2 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KUM63451.1 - 1.3e-09 38.4 7.4 4.3e-07 30.3 1.9 2.8 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 KUM63451.1 - 4.1e-09 35.7 3.0 0.00027 20.6 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KUM63451.1 - 7.6e-05 22.0 3.2 0.12 12.0 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KUM63451.1 - 0.0015 18.3 4.2 0.25 11.2 0.3 3.0 2 1 1 3 3 3 2 EF-hand domain pair C1_2 PF03107.16 KUM63451.1 - 0.0072 16.6 3.8 0.013 15.8 3.8 1.4 1 0 0 1 1 1 1 C1 domain Ribosomal_60s PF00428.19 KUM63451.1 - 0.14 12.7 0.8 0.61 10.7 0.8 2.1 1 1 0 1 1 1 0 60s Acidic ribosomal protein MFS_1 PF07690.16 KUM63452.1 - 9.3e-20 70.8 50.3 2e-19 69.8 47.1 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Cys_Met_Meta_PP PF01053.20 KUM63455.1 - 9.1e-32 110.0 0.0 1.2e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KUM63455.1 - 4.6e-05 22.8 0.0 6.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3506 PF12014.8 KUM63456.1 - 3.8e-54 182.5 0.0 7.3e-54 181.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 KUM63456.1 - 7.2e-12 45.0 0.0 2.2e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KUM63456.1 - 4.2e-07 29.7 0.1 1.3e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KUM63456.1 - 0.0054 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box DUF1748 PF08520.10 KUM63457.1 - 2.2e-38 130.0 0.1 2.5e-38 129.8 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Cornichon PF03311.14 KUM63458.1 - 9.8e-37 126.0 8.5 1.2e-36 125.7 8.5 1.1 1 0 0 1 1 1 1 Cornichon protein MMR_HSR1 PF01926.23 KUM63459.1 - 6.1e-10 39.2 0.2 2.2e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KUM63459.1 - 6.1e-06 26.2 1.7 9.7e-06 25.6 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KUM63459.1 - 9e-06 25.2 0.0 9e-06 25.2 0.0 2.0 3 0 0 3 3 3 1 AIG1 family Septin PF00735.18 KUM63459.1 - 0.0012 18.2 0.0 0.0037 16.6 0.0 1.8 1 0 0 1 1 1 1 Septin DUF3040 PF11239.8 KUM63459.1 - 0.033 14.4 0.2 0.39 11.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) AAA_18 PF13238.6 KUM63459.1 - 0.036 14.6 0.0 0.036 14.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KUM63459.1 - 0.038 13.5 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B TctA PF01970.16 KUM63459.1 - 0.046 12.4 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family AAA_29 PF13555.6 KUM63459.1 - 0.13 12.0 0.2 0.37 10.6 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 KUM63459.1 - 0.13 12.3 10.9 2.9 7.9 0.0 4.1 3 1 0 3 3 2 0 Dynamin family ABC_tran PF00005.27 KUM63459.1 - 0.39 11.2 0.0 0.39 11.2 0.0 3.1 2 1 0 2 2 1 0 ABC transporter AAA_22 PF13401.6 KUM63459.1 - 0.39 11.0 4.2 1.1 9.5 0.0 2.8 2 1 1 3 3 3 0 AAA domain Golgin_A5 PF09787.9 KUM63459.1 - 3.4 7.0 33.2 0.24 10.8 20.9 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 MeaB PF03308.16 KUM63459.1 - 5.1 6.0 5.5 1 8.3 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB UNC-93 PF05978.16 KUM63460.1 - 4e-16 59.1 2.0 4e-16 59.1 2.0 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KUM63460.1 - 2.4e-13 49.8 25.6 2.4e-13 49.8 25.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM63460.1 - 0.0059 15.5 4.7 0.0059 15.5 4.7 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KUM63460.1 - 0.054 11.8 6.1 0.063 11.6 0.7 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family NPHI_C PF08469.10 KUM63461.1 - 0.086 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal DUF1769 PF08588.10 KUM63462.1 - 5.2e-16 58.6 0.9 1.6e-15 57.0 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) 3Beta_HSD PF01073.19 KUM63465.1 - 3.9e-19 68.7 0.0 4.6e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KUM63465.1 - 4.1e-05 23.1 0.0 5.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM63465.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase PK PF00224.21 KUM63466.1 - 1.9e-173 576.2 2.6 2.4e-173 575.9 2.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KUM63466.1 - 9.3e-39 132.3 0.0 2.8e-38 130.7 0.0 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KUM63466.1 - 0.00028 20.1 0.4 0.0007 18.8 0.2 1.7 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KUM63466.1 - 0.033 13.2 0.1 0.28 10.1 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Beta-lactamase PF00144.24 KUM63467.1 - 2.4e-60 204.5 0.4 3.3e-60 204.1 0.4 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KUM63467.1 - 0.009 15.5 0.3 0.13 11.6 0.1 2.2 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 KUM63467.1 - 0.012 15.2 0.1 0.031 13.9 0.1 1.6 1 0 0 1 1 1 0 Beta-lactamase enzyme family Microvir_J PF04726.13 KUM63467.1 - 0.19 11.7 0.1 0.36 10.8 0.1 1.4 1 0 0 1 1 1 0 Microvirus J protein Lipase_GDSL_2 PF13472.6 KUM63469.1 - 2.6e-05 24.7 4.5 4.1e-05 24.1 4.5 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KUM63469.1 - 0.00081 19.4 0.1 0.001 19.1 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Iso_dh PF00180.20 KUM63471.1 - 1.2e-97 327.2 0.0 3e-97 325.9 0.0 1.5 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_S8 PF00410.19 KUM63473.1 - 5.5e-15 55.4 0.0 4.2e-14 52.6 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S8 LPP PF04728.13 KUM63474.1 - 0.029 14.8 0.2 0.093 13.1 0.2 1.9 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Epimerase PF01370.21 KUM63475.1 - 1.2e-25 90.4 0.0 1.4e-25 90.2 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KUM63475.1 - 1.3e-21 76.8 0.0 1.6e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KUM63475.1 - 9e-13 48.3 0.0 1.1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KUM63475.1 - 1.5e-10 41.3 0.0 1.7e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KUM63475.1 - 2e-10 40.3 0.0 2.5e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KUM63475.1 - 1.2e-09 37.7 0.0 2.1e-09 36.9 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KUM63475.1 - 6.2e-09 36.0 0.0 1.3e-08 35.0 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KUM63475.1 - 1.3e-07 31.1 0.0 0.0011 18.2 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.25 KUM63475.1 - 3.1e-06 26.8 0.0 4.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KUM63475.1 - 6.4e-06 26.4 0.0 8.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KUM63475.1 - 8.7e-05 22.8 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain adh_short_C2 PF13561.6 KUM63475.1 - 0.00014 21.5 0.0 0.00019 21.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 KUM63475.1 - 0.00025 20.7 0.0 0.00044 19.9 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 KUM63475.1 - 0.027 14.6 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_tran_WecB PF03808.13 KUM63475.1 - 0.03 14.3 0.0 0.49 10.3 0.0 2.0 1 1 1 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Semialdhyde_dh PF01118.24 KUM63475.1 - 0.056 13.9 0.0 0.081 13.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 KUM63475.1 - 0.057 14.1 0.0 0.085 13.5 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF1132 PF06575.12 KUM63475.1 - 0.075 13.4 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) Cellulase PF00150.18 KUM63477.1 - 3.5e-44 151.3 0.6 5.1e-44 150.8 0.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) WD40 PF00400.32 KUM63478.1 - 1e-14 54.6 29.4 5e-05 24.0 0.3 11.1 11 0 0 11 11 11 7 WD domain, G-beta repeat Pil1 PF13805.6 KUM63481.1 - 1.7e-122 408.1 0.1 2.1e-122 407.7 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 APG6_N PF17675.1 KUM63481.1 - 5 7.7 8.1 23 5.5 0.1 2.8 3 1 0 3 3 3 0 Apg6 coiled-coil region XPG_N PF00752.17 KUM63482.1 - 8.4e-35 119.3 0.6 4.8e-34 116.9 0.0 2.5 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KUM63482.1 - 2.3e-25 88.8 0.9 6.9e-25 87.2 0.0 2.3 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 KUM63482.1 - 5.8e-05 23.6 0.0 0.00023 21.7 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.20 KUM63482.1 - 0.0001 22.0 10.7 0.002 17.9 1.0 3.6 3 0 0 3 3 3 2 Ubiquitin interaction motif Transposase_20 PF02371.16 KUM63482.1 - 0.014 15.7 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family PUB_1 PF18486.1 KUM63482.1 - 0.088 12.7 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain HHH_5 PF14520.6 KUM63482.1 - 0.088 13.4 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain SUR7 PF06687.12 KUM63483.1 - 9e-48 162.7 13.4 1.1e-47 162.4 13.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF3742 PF12553.8 KUM63483.1 - 0.45 10.7 5.5 1 9.5 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3742) LapA_dom PF06305.11 KUM63483.1 - 0.6 10.0 0.0 0.6 10.0 0.0 2.7 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain DUF4191 PF13829.6 KUM63483.1 - 1.6 8.0 4.3 2.6 7.3 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) PIP5K PF01504.18 KUM63484.1 - 5.4e-33 114.4 0.0 5.3e-25 88.2 0.1 2.8 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KUM63484.1 - 8.9e-27 93.9 0.0 1.5e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KUM63484.1 - 1.1e-14 54.3 3.9 1.1e-14 54.3 3.9 2.0 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.22 KUM63484.1 - 0.19 11.6 7.2 0.044 13.7 3.2 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Aconitase PF00330.20 KUM63485.1 - 2.4e-140 468.6 0.0 3.4e-140 468.1 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KUM63485.1 - 6.4e-43 146.2 0.0 1.1e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain PrpF PF04303.13 KUM63486.1 - 7.4e-81 272.0 0.4 1.1e-80 271.4 0.4 1.1 1 0 0 1 1 1 1 PrpF protein RraA-like PF03737.15 KUM63486.1 - 3.8e-35 121.2 0.0 6.2e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Aldolase/RraA Fungal_trans PF04082.18 KUM63487.1 - 6e-15 55.0 0.2 6e-15 55.0 0.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain AA_permease PF00324.21 KUM63488.1 - 4.3e-107 358.6 37.9 5.4e-107 358.3 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM63488.1 - 1e-28 100.4 42.1 2.1e-28 99.3 42.1 1.5 1 1 0 1 1 1 1 Amino acid permease OPA3 PF07047.12 KUM63490.1 - 4.3e-47 159.0 3.2 7.3e-47 158.2 3.2 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) BatD PF13584.6 KUM63490.1 - 0.013 14.3 0.6 0.013 14.3 0.6 1.7 2 0 0 2 2 2 0 Oxygen tolerance Troponin PF00992.20 KUM63490.1 - 0.021 15.1 0.9 0.021 15.1 0.9 1.7 2 0 0 2 2 2 0 Troponin FSH1 PF03959.13 KUM63491.1 - 0.041 13.5 0.0 0.047 13.3 0.0 1.3 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Ring_hydroxyl_A PF00848.19 KUM63492.1 - 1.4e-26 93.8 3.6 8.4e-15 55.3 0.1 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KUM63492.1 - 9.8e-15 54.3 0.0 1.9e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DAO PF01266.24 KUM63493.1 - 4.8e-33 115.2 0.1 3.4e-17 63.1 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM63493.1 - 5.3e-06 25.9 0.0 2.4e-05 23.7 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM63493.1 - 1.7e-05 24.1 0.0 0.0061 15.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KUM63493.1 - 1.9e-05 24.8 0.0 4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KUM63493.1 - 0.00012 21.3 0.1 0.022 13.9 0.0 2.3 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KUM63493.1 - 0.0002 21.4 0.0 0.95 9.4 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KUM63493.1 - 0.00038 19.8 0.0 0.0067 15.7 0.0 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KUM63493.1 - 0.00079 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Glu_dehyd_C PF16912.5 KUM63493.1 - 0.0056 16.2 0.0 0.041 13.4 0.0 2.0 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Thi4 PF01946.17 KUM63493.1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KUM63493.1 - 0.021 13.9 0.1 2.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 KUM63493.1 - 0.03 14.4 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KUM63493.1 - 0.049 13.9 0.0 0.081 13.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 KUM63493.1 - 0.05 14.2 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KUM63493.1 - 0.086 11.5 0.0 3.9 6.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Sacchrp_dh_NADP PF03435.18 KUM63493.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Zn_clus PF00172.18 KUM63495.1 - 4.5e-05 23.5 8.0 8.6e-05 22.6 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KUM63495.1 - 8.8 6.9 10.1 12 6.5 2.2 2.4 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Sugar_tr PF00083.24 KUM63496.1 - 2.4e-125 419.0 24.9 2.7e-125 418.8 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM63496.1 - 1.7e-21 76.5 34.6 5.1e-14 52.0 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 KUM63496.1 - 0.018 15.6 0.2 0.039 14.5 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Metallophos PF00149.28 KUM63497.1 - 1.2e-09 39.0 0.0 7.8e-09 36.3 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.24 KUM63498.1 - 3.1e-09 36.2 3.7 0.00037 19.5 2.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KUM63498.1 - 1.1e-06 27.9 14.0 0.0001 21.4 9.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DAO PF01266.24 KUM63499.1 - 2.4e-41 142.5 0.2 2.7e-41 142.4 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KUM63499.1 - 0.0092 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Staphylcoagulse PF04022.12 KUM63500.1 - 0.025 14.1 0.0 0.075 12.6 0.0 1.7 1 0 0 1 1 1 0 Staphylocoagulase repeat Lipase_GDSL_2 PF13472.6 KUM63501.1 - 3.1e-16 60.3 0.0 4.3e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KUM63501.1 - 1.8e-09 37.9 0.0 1.9e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KUM63501.1 - 1.2e-05 25.5 0.0 1.7e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF2817 PF10994.8 KUM63501.1 - 0.078 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) Dynamin_M PF01031.20 KUM63501.1 - 0.083 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Dynamin central region NRIP1_repr_4 PF15690.5 KUM63501.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 4 Acetyltransf_10 PF13673.7 KUM63502.1 - 1.2e-08 34.9 0.0 1.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KUM63502.1 - 8e-08 32.6 0.0 1.3e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM63502.1 - 8e-08 32.5 0.0 9.8e-08 32.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KUM63502.1 - 0.00073 19.6 0.1 0.011 15.9 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain 2-Hacid_dh_C PF02826.19 KUM63503.1 - 8.4e-40 136.0 0.1 1.8e-25 89.3 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KUM63503.1 - 0.00052 19.7 0.0 0.00077 19.1 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3HCDH_N PF02737.18 KUM63503.1 - 0.021 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KUM63503.1 - 0.039 14.5 0.0 0.081 13.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent VPS13_C PF16909.5 KUM63504.1 - 0.54 10.0 4.2 0.5 10.1 0.4 2.3 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal MFS_1 PF07690.16 KUM63506.1 - 4.5e-46 157.4 48.6 3.2e-44 151.3 51.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM63506.1 - 3.3e-22 78.7 23.7 4.4e-22 78.3 23.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM63506.1 - 2.8e-15 56.1 10.9 2.8e-15 56.1 10.9 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter DNA_processg_A PF02481.15 KUM63506.1 - 0.086 12.1 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 DNA recombination-mediator protein A OATP PF03137.20 KUM63506.1 - 0.4 8.9 15.6 0.24 9.7 4.6 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Epimerase PF01370.21 KUM63507.1 - 6.4e-12 45.4 0.3 4.9e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KUM63507.1 - 1.1e-06 28.7 0.1 1.7e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KUM63507.1 - 1.4e-05 24.2 0.0 0.041 12.9 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KUM63507.1 - 0.00013 21.6 0.2 0.00019 21.1 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KUM63507.1 - 0.00047 20.6 0.0 0.001 19.5 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KUM63507.1 - 0.0017 17.9 0.0 0.027 13.9 0.0 2.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KUM63507.1 - 0.028 14.7 0.2 0.15 12.3 0.1 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Dala_Dala_lig_C PF07478.13 KUM63508.1 - 6.1e-13 48.8 0.0 8.7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KUM63508.1 - 0.00075 19.6 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 KUM63508.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KUM63508.1 - 0.0017 17.9 0.1 0.0049 16.5 0.1 1.8 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KUM63508.1 - 0.0019 17.7 0.1 0.0087 15.6 0.1 1.9 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 KUM63508.1 - 0.0042 16.9 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KUM63508.1 - 0.096 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Pkinase PF00069.25 KUM63509.1 - 6e-69 232.3 0.0 9e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM63509.1 - 1.6e-42 145.6 0.0 2.4e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KUM63509.1 - 3.4e-08 33.5 0.2 0.0045 17.1 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KUM63509.1 - 8.4e-07 28.6 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KUM63509.1 - 0.057 12.4 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KUM63509.1 - 0.36 9.6 1.4 0.43 9.3 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Amidohydro_2 PF04909.14 KUM63510.1 - 8.5e-24 84.8 0.0 1.5e-23 84.0 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase Mito_carr PF00153.27 KUM63511.1 - 5.7e-22 77.5 1.5 5.5e-12 45.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Hormone_1 PF00103.20 KUM63511.1 - 0.2 11.3 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Somatotropin hormone family Sugar_tr PF00083.24 KUM63512.1 - 2.1e-79 267.5 21.0 2.7e-79 267.1 21.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM63512.1 - 4.3e-21 75.2 16.5 4.3e-21 75.2 16.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Myosin_head PF00063.21 KUM63513.1 - 1.9e-244 812.9 1.0 2.3e-244 812.7 1.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KUM63513.1 - 5.4e-53 179.5 0.0 1.1e-52 178.5 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KUM63513.1 - 1.4e-12 47.0 0.3 3.6e-12 45.7 0.2 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KUM63513.1 - 1.2e-08 34.7 0.1 3.1e-08 33.3 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KUM63513.1 - 4.7e-08 32.6 0.0 1.4e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 KUM63513.1 - 0.017 14.8 9.7 0.61 10.0 1.0 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_16 PF13191.6 KUM63513.1 - 0.042 14.2 0.0 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KUM63513.1 - 0.059 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KUM63513.1 - 0.095 12.6 0.1 0.28 11.1 0.1 1.8 2 0 0 2 2 2 0 NACHT domain Hpr_kinase_C PF07475.12 KUM63513.1 - 0.17 11.4 1.2 8.9 5.8 0.1 2.7 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain SH3_3 PF08239.11 KUM63513.1 - 0.23 11.8 0.9 0.56 10.5 0.9 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain HNH_2 PF13391.6 KUM63515.1 - 2.8e-16 59.4 0.0 4.8e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease MFS_1 PF07690.16 KUM63516.1 - 9.2e-37 126.8 49.9 1.6e-35 122.7 48.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily S_4TM PF18159.1 KUM63516.1 - 0.71 9.1 3.8 0.27 10.5 0.5 2.0 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain OATP PF03137.20 KUM63516.1 - 0.94 7.7 13.3 1.2 7.3 3.9 2.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Cation_efflux PF01545.21 KUM63517.1 - 2.7e-17 63.2 0.0 3.4e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KUM63517.1 - 0.01 15.9 0.2 0.021 14.9 0.2 1.5 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter Zip PF02535.22 KUM63517.1 - 0.073 12.3 0.3 0.11 11.7 0.1 1.4 2 0 0 2 2 2 0 ZIP Zinc transporter Glyco_transf_28 PF03033.20 KUM63518.1 - 5e-17 62.2 0.0 5.2e-15 55.7 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 KUM63519.1 - 4.6e-07 30.1 0.0 2.5e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 KUM63519.1 - 2.5e-06 26.6 0.0 3.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KUM63519.1 - 3.7e-05 23.8 0.0 8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Ldt_C PF17969.1 KUM63519.1 - 0.15 12.8 0.7 0.37 11.5 0.0 1.9 2 0 0 2 2 2 0 L,D-transpeptidase C-terminal domain PRONE PF03759.13 KUM63520.1 - 0.018 13.9 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) F-box-like PF12937.7 KUM63521.1 - 0.0014 18.4 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like DHHC PF01529.20 KUM63523.1 - 3e-24 85.6 7.8 3e-24 85.6 7.8 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 KUM63523.1 - 0.035 14.0 1.5 0.055 13.4 1.5 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily Methyltransf_25 PF13649.6 KUM63525.1 - 1.5e-17 64.0 0.0 1.6e-16 60.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM63525.1 - 1.9e-14 54.1 0.0 4e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM63525.1 - 2.7e-13 50.5 0.0 5.3e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM63525.1 - 3.4e-12 46.5 0.0 5.2e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM63525.1 - 1.6e-11 44.2 0.0 2.1e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KUM63525.1 - 8.1e-08 32.0 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KUM63525.1 - 2.8e-05 23.6 0.0 4.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 KUM63525.1 - 8.5e-05 22.3 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 KUM63525.1 - 0.00022 20.3 0.0 0.00039 19.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 KUM63525.1 - 0.00028 20.4 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 KUM63525.1 - 0.00061 18.9 0.0 0.00087 18.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 KUM63525.1 - 0.0017 18.2 0.0 0.0043 16.8 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.12 KUM63525.1 - 0.0029 16.7 0.0 0.0046 16.1 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.20 KUM63525.1 - 0.0048 16.2 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 KUM63525.1 - 0.015 15.3 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pox_MCEL PF03291.16 KUM63525.1 - 0.033 13.3 0.0 0.054 12.6 0.0 1.4 1 1 0 1 1 1 0 mRNA capping enzyme TehB PF03848.14 KUM63525.1 - 0.037 13.5 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB MetW PF07021.12 KUM63525.1 - 0.088 12.4 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_5 PF01795.19 KUM63525.1 - 0.19 11.2 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family HATPase_c_3 PF13589.6 KUM63526.1 - 1.1e-11 44.8 0.1 2.6e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KUM63526.1 - 8.8e-11 42.3 0.1 6.3e-10 39.5 0.1 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 KUM63526.1 - 1.1e-08 34.7 0.0 2.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain DUF1295 PF06966.12 KUM63527.1 - 2.8e-34 118.7 0.0 4e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KUM63527.1 - 0.00081 19.8 0.1 0.0021 18.4 0.1 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.16 KUM63527.1 - 0.0031 17.5 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.17 KUM63527.1 - 0.008 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 KUM63527.1 - 0.0093 16.4 0.0 0.03 14.7 0.0 1.9 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family p450 PF00067.22 KUM63529.1 - 4.1e-73 246.7 0.0 5.2e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KUM63529.1 - 2.8e-25 89.2 0.0 4.9e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KUM63529.1 - 6.9e-18 65.2 0.0 1.2e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KUM63529.1 - 7.7e-12 45.8 0.0 1.6e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KUM63529.1 - 0.0018 18.4 0.0 0.025 14.7 0.0 2.7 4 0 0 4 4 4 1 Ferric reductase NAD binding domain p450 PF00067.22 KUM63530.1 - 2.3e-83 280.5 0.0 3.1e-83 280.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KUM63530.1 - 3.2e-27 95.5 0.0 4.9e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KUM63530.1 - 1.5e-24 86.8 0.1 2.7e-23 82.7 0.1 2.8 2 1 0 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.21 KUM63530.1 - 1.3e-08 35.5 0.0 2.9e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KUM63530.1 - 0.0007 19.9 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain ABC2_membrane PF01061.24 KUM63531.1 - 1.2e-82 276.4 46.0 4.4e-44 150.4 16.8 2.9 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KUM63531.1 - 4.8e-33 112.9 10.3 3.2e-28 97.5 0.1 4.3 5 0 0 5 5 4 2 CDR ABC transporter ABC_tran PF00005.27 KUM63531.1 - 1e-31 110.3 0.0 1.3e-15 58.1 0.0 3.4 3 1 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 KUM63531.1 - 2e-14 53.9 0.1 4.8e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KUM63531.1 - 1.5e-07 32.0 0.5 0.0011 19.4 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KUM63531.1 - 2e-06 27.8 0.2 0.00017 21.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KUM63531.1 - 3.2e-06 26.9 0.1 0.00045 19.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KUM63531.1 - 6.9e-06 26.3 0.1 0.0049 17.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KUM63531.1 - 0.00027 21.5 0.3 0.041 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KUM63531.1 - 0.00055 19.6 0.5 0.81 9.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 KUM63531.1 - 0.00078 18.7 39.1 0.068 12.3 17.0 3.0 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_22 PF13401.6 KUM63531.1 - 0.00078 19.7 0.1 0.3 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KUM63531.1 - 0.0016 17.9 0.0 0.32 10.4 0.0 3.6 4 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KUM63531.1 - 0.0024 17.6 0.2 0.34 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KUM63531.1 - 0.0029 17.2 1.3 0.12 11.9 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KUM63531.1 - 0.0077 16.7 0.6 6.9 7.1 0.1 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KUM63531.1 - 0.012 16.1 0.3 2.3 8.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KUM63531.1 - 0.013 15.4 0.7 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.6 KUM63531.1 - 0.015 15.1 0.2 5.4 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 KUM63531.1 - 0.024 14.9 0.7 0.29 11.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KUM63531.1 - 0.033 14.2 0.6 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KUM63531.1 - 0.033 14.1 0.0 9.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 KUM63531.1 - 0.044 13.9 0.4 1.1 9.4 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase T2SSE PF00437.20 KUM63531.1 - 0.05 12.7 0.3 8.1 5.4 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 KUM63531.1 - 0.13 12.6 0.1 14 6.1 0.0 2.9 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 KUM63531.1 - 0.14 11.9 0.1 14 5.4 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 KUM63531.1 - 0.2 11.4 0.1 5 6.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 KUM63531.1 - 0.36 10.6 1.7 18 5.0 0.2 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain SMC_N PF02463.19 KUM63532.1 - 1.2e-77 260.3 0.1 3.5e-77 258.7 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KUM63532.1 - 4.5e-24 85.0 0.0 6.3e-23 81.3 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KUM63532.1 - 2.7e-12 47.1 1.9 4.7e-05 23.4 0.0 4.0 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KUM63532.1 - 0.00055 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.8 KUM63532.1 - 0.00088 16.9 43.3 0.00088 16.9 43.3 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3584) Cob_adeno_trans PF01923.18 KUM63532.1 - 0.0015 18.7 1.9 0.0015 18.7 1.9 5.8 3 2 2 6 6 6 1 Cobalamin adenosyltransferase Tropomyosin_1 PF12718.7 KUM63532.1 - 0.0023 18.1 11.9 0.0023 18.1 11.9 7.6 2 2 5 7 7 7 2 Tropomyosin like DUF5082 PF16888.5 KUM63532.1 - 0.028 14.7 0.2 0.028 14.7 0.2 7.6 3 2 4 8 8 8 0 Domain of unknown function (DUF5082) SbcCD_C PF13558.6 KUM63532.1 - 0.028 14.6 0.0 0.71 10.1 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 KUM63532.1 - 1.8 9.0 0.0 1.8 9.0 0.0 5.6 3 2 0 4 4 4 0 ABC transporter FAD_binding_4 PF01565.23 KUM63534.1 - 1.9e-16 60.1 0.1 2.8e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 KUM63534.1 - 5.9e-05 23.0 0.8 5.9e-05 23.0 0.8 1.9 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase CUE PF02845.16 KUM63535.1 - 5.8e-06 25.9 0.1 1e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 CUE domain FA_desaturase PF00487.24 KUM63536.1 - 3.1e-26 92.8 26.2 4.2e-26 92.3 26.2 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KUM63536.1 - 4.7e-11 42.7 0.0 9.7e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Unstab_antitox PF09720.10 KUM63536.1 - 0.0078 16.2 0.8 0.12 12.4 0.1 2.5 2 0 0 2 2 2 1 Putative addiction module component PGM_PMM_I PF02878.16 KUM63537.1 - 8.3e-37 126.0 0.0 1.8e-36 124.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KUM63537.1 - 1.2e-23 83.6 0.0 3.3e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KUM63537.1 - 1.8e-15 57.2 0.2 3.2e-15 56.3 0.2 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KUM63537.1 - 3.4e-07 30.4 0.0 1.1e-06 28.7 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pkinase PF00069.25 KUM63538.1 - 3.3e-11 43.0 0.0 5.1e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KUM63538.1 - 6.7e-08 32.7 0.4 2e-07 31.2 0.4 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KUM63538.1 - 1.7e-05 24.2 0.0 2.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KUM63538.1 - 3.2e-05 23.4 0.1 4.4e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KUM63538.1 - 0.00013 21.6 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KUM63538.1 - 0.0066 15.3 0.1 0.01 14.6 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KUM63538.1 - 0.043 13.4 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-C2H2_jaz PF12171.8 KUM63539.1 - 2.3e-46 155.2 26.9 1.3e-06 28.6 0.0 8.4 8 0 0 8 8 8 8 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KUM63539.1 - 1.5e-40 136.4 31.2 7.4e-06 26.2 0.1 9.1 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KUM63539.1 - 1.1e-27 94.3 29.5 0.0035 18.1 0.1 8.5 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2 PF00096.26 KUM63539.1 - 3.1e-20 71.4 33.7 0.036 14.5 0.1 8.6 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KUM63539.1 - 1.9e-14 53.3 33.0 0.014 15.4 0.1 8.9 9 0 0 9 9 9 6 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KUM63539.1 - 8.1e-10 38.3 25.6 0.25 11.1 0.2 8.0 8 0 0 8 8 8 6 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KUM63539.1 - 1.9e-09 37.5 27.4 3.5 8.2 0.2 8.5 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2_2 PF12756.7 KUM63539.1 - 3.3e-07 30.6 26.5 0.52 10.7 0.0 8.2 2 1 7 9 9 8 3 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KUM63539.1 - 5e-07 29.5 22.5 0.47 10.4 0.0 8.0 8 0 0 8 8 8 2 zinc-finger of a C2HC-type LIM PF00412.22 KUM63539.1 - 9.3e-06 25.8 22.5 0.4 10.9 0.8 4.8 3 1 0 4 4 4 4 LIM domain zf_UBZ PF18439.1 KUM63539.1 - 9.6e-05 21.9 27.6 4.4 7.0 0.1 8.0 8 0 0 8 8 8 4 Ubiquitin-Binding Zinc Finger HTH_5 PF01022.20 KUM63539.1 - 0.00035 20.4 4.5 1.3 8.9 0.0 4.6 6 0 0 6 6 6 2 Bacterial regulatory protein, arsR family ADK_lid PF05191.14 KUM63539.1 - 0.00054 19.9 8.0 2.5 8.1 0.2 6.1 5 3 2 7 7 7 1 Adenylate kinase, active site lid zf-DBF PF07535.12 KUM63539.1 - 0.0011 19.1 17.1 0.17 12.0 0.1 6.9 7 0 0 7 7 7 1 DBF zinc finger zf-3CxxC_2 PF17180.4 KUM63539.1 - 0.0047 17.6 16.1 53 4.7 0.1 7.1 7 0 0 7 7 7 0 Zinc-binding domain zf_Hakai PF18408.1 KUM63539.1 - 0.0058 16.3 23.4 4.1 7.2 0.4 7.2 8 0 0 8 8 8 2 C2H2 Hakai zinc finger domain DUF4764 PF15961.5 KUM63539.1 - 0.031 13.0 6.2 1.3 7.6 0.2 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4764) C1_4 PF07975.12 KUM63539.1 - 0.33 11.2 29.6 8.4 6.7 0.8 6.5 1 1 6 7 7 7 0 TFIIH C1-like domain Yippee-Mis18 PF03226.14 KUM63539.1 - 0.5 10.6 16.1 10 6.4 5.4 3.3 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.6 KUM63539.1 - 1.5 8.8 21.1 33 4.5 0.7 7.3 6 2 1 7 7 7 0 HNH endonuclease EPF PF17181.4 KUM63539.1 - 2.6 8.1 23.4 4.6 7.3 1.7 5.4 2 2 2 4 4 4 0 Epidermal patterning factor proteins Presenilin PF01080.17 KUM63541.1 - 0.31 9.8 2.4 0.38 9.5 2.4 1.1 1 0 0 1 1 1 0 Presenilin zf-CCCH_4 PF18044.1 KUM63543.1 - 2.2e-08 33.7 3.2 4.2e-08 32.8 3.2 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KUM63543.1 - 4.6e-07 29.6 2.9 1e-06 28.5 2.9 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KUM63543.1 - 3.1e-06 27.0 7.2 3.1e-06 27.0 7.2 1.8 2 0 0 2 2 2 1 Zinc finger domain NupH_GANP PF16768.5 KUM63543.1 - 0.0047 16.7 33.0 0.0047 16.7 33.0 3.3 1 1 2 3 3 3 1 Nucleoporin homology of Germinal-centre associated nuclear protein Torus PF16131.5 KUM63543.1 - 0.06 14.0 0.8 0.11 13.2 0.8 1.4 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 KUM63543.1 - 0.11 13.0 4.7 0.23 12.0 4.7 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Nucleoporin_FG PF13634.6 KUM63543.1 - 6.1 7.8 91.5 13 6.7 24.4 5.5 2 2 2 4 4 4 0 Nucleoporin FG repeat region Ribosomal_S10 PF00338.22 KUM63544.1 - 6.2e-26 90.5 0.3 7.3e-26 90.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-RING_2 PF13639.6 KUM63545.1 - 2.2e-08 34.3 9.6 3.8e-08 33.5 9.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KUM63545.1 - 7.3e-06 25.8 5.5 1.1e-05 25.2 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM63545.1 - 1.8e-05 24.5 9.1 3e-05 23.8 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KUM63545.1 - 2.2e-05 24.2 10.6 3.6e-05 23.5 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KUM63545.1 - 0.00017 21.8 8.8 0.00054 20.2 8.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KUM63545.1 - 0.067 13.2 6.7 0.14 12.2 6.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.20 KUM63545.1 - 0.73 9.6 7.4 1.2 8.9 7.4 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_11 PF17123.5 KUM63545.1 - 2.5 7.9 5.1 5.5 6.8 5.1 1.5 1 0 0 1 1 1 0 RING-like zinc finger Drc1-Sld2 PF11719.8 KUM63546.1 - 1.8e-115 387.1 28.1 2.3e-115 386.7 28.1 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein Sec31 PF11549.8 KUM63546.1 - 0.59 10.1 5.4 1.1 9.2 0.2 3.4 3 0 0 3 3 3 0 Protein transport protein SEC31 GMC_oxred_N PF00732.19 KUM63547.1 - 8.4e-81 271.6 0.0 1.2e-80 271.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM63547.1 - 2.8e-28 99.3 0.0 4.8e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KUM63547.1 - 0.0015 18.8 0.0 0.0044 17.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KUM63547.1 - 0.0024 17.1 0.1 0.019 14.2 0.1 2.0 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KUM63547.1 - 0.004 16.8 0.1 0.0082 15.8 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KUM63547.1 - 0.034 13.2 0.0 0.081 12.0 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KUM63547.1 - 0.048 12.7 0.1 0.13 11.2 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein HAD_SAK_1 PF10307.9 KUM63548.1 - 5.7e-78 261.4 0.0 8e-78 260.9 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Suc_Fer-like PF06999.12 KUM63549.1 - 9.7e-70 234.4 0.0 1.1e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Flavi_NS4A PF01350.17 KUM63549.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A Fungal_trans PF04082.18 KUM63550.1 - 5e-11 42.1 1.2 5e-11 42.1 1.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM63550.1 - 4.3e-09 36.3 7.8 8.8e-09 35.4 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_16 PF00722.21 KUM63552.1 - 1.3e-41 142.0 6.0 2.2e-41 141.2 6.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF903 PF06004.12 KUM63552.1 - 0.24 11.3 0.7 4.2 7.3 0.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) ELYS PF13934.6 KUM63553.1 - 1.1e-66 225.0 1.1 1.3e-66 224.7 1.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly Glyco_hydro_43 PF04616.14 KUM63554.1 - 4.8e-36 124.5 1.6 6.3e-36 124.2 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 adh_short_C2 PF13561.6 KUM63555.1 - 9.2e-55 185.7 2.4 1.1e-54 185.5 2.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM63555.1 - 3.5e-38 131.0 2.5 4.1e-38 130.8 2.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM63555.1 - 3.2e-10 40.2 3.1 4.7e-10 39.7 3.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KUM63555.1 - 0.025 14.5 0.2 0.044 13.7 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KUM63555.1 - 0.038 13.3 0.1 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KUM63556.1 - 3.1e-08 33.0 0.1 5.9e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMO-like PF00743.19 KUM63557.1 - 3.7e-22 78.4 0.5 6.3e-10 38.1 0.0 4.0 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KUM63557.1 - 6.9e-12 45.2 0.0 1.9e-07 30.6 0.2 3.0 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM63557.1 - 8.2e-08 31.9 5.9 0.0008 18.7 0.2 4.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM63557.1 - 8.8e-07 29.0 0.3 0.003 17.6 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KUM63557.1 - 8.2e-06 26.0 0.0 2.4e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM63557.1 - 0.027 14.0 3.1 2.3 7.7 0.3 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF371 PF04027.13 KUM63557.1 - 0.087 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF371) K_oxygenase PF13434.6 KUM63557.1 - 0.092 11.9 1.0 17 4.4 0.1 3.1 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KUM63557.1 - 0.093 12.0 0.1 0.26 10.5 0.1 1.7 1 0 0 1 1 1 0 Thi4 family Semialdhyde_dh PF01118.24 KUM63557.1 - 0.14 12.6 0.0 1.1 9.8 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain MAM33 PF02330.16 KUM63558.1 - 1.6e-66 224.3 8.5 2e-66 224.0 8.5 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein T3SS_needle_E PF08988.10 KUM63558.1 - 0.0029 17.7 0.1 0.0087 16.2 0.1 1.8 1 0 0 1 1 1 1 Type III secretion system, cytoplasmic E component of needle DNA_primase_S PF01896.19 KUM63559.1 - 2.6e-57 193.7 0.1 3.6e-57 193.3 0.1 1.2 1 0 0 1 1 1 1 DNA primase small subunit DUF1236 PF06823.12 KUM63560.1 - 0.36 10.7 9.7 1.5 8.8 1.9 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1236) DUF452 PF04301.13 KUM63560.1 - 0.68 9.4 2.2 33 3.9 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF452) XPG_I PF00867.18 KUM63561.1 - 3.2e-24 85.1 0.1 5.9e-24 84.3 0.1 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KUM63561.1 - 1.9e-23 82.8 0.0 1.4e-22 80.1 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 KUM63561.1 - 5.7e-05 22.7 0.0 9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing Tma16 PF11176.8 KUM63562.1 - 9.6e-51 171.5 3.0 1.2e-50 171.2 3.0 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 DUF4777 PF16007.5 KUM63562.1 - 0.0026 18.0 0.1 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4777) Cauli_AT PF03233.13 KUM63562.1 - 0.058 13.3 0.6 0.082 12.8 0.6 1.2 1 0 0 1 1 1 0 Aphid transmission protein Mgr1 PF08602.10 KUM63562.1 - 0.071 11.9 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Fig1 PF12351.8 KUM63564.1 - 4.1e-61 206.2 4.7 4.1e-61 206.2 4.7 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 KUM63564.1 - 3.4e-06 26.9 8.7 4.2e-06 26.5 8.0 1.5 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 KUM63564.1 - 0.00019 20.6 2.6 0.00019 20.6 2.6 1.7 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) ODV-E18 PF10717.9 KUM63564.1 - 0.48 10.3 0.0 0.48 10.3 0.0 3.1 3 1 1 4 4 4 0 Occlusion-derived virus envelope protein ODV-E18 DUF751 PF05421.11 KUM63564.1 - 0.49 11.2 0.0 0.49 11.2 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF751) DUF2207 PF09972.9 KUM63564.1 - 0.5 9.1 16.3 0.81 8.4 0.1 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Claudin_2 PF13903.6 KUM63564.1 - 1.3 8.7 15.6 0.034 13.9 7.7 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction adh_short PF00106.25 KUM63565.1 - 7.2e-54 182.2 0.1 8.6e-54 182.0 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM63565.1 - 2.2e-34 119.1 0.0 2.8e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM63565.1 - 2.3e-13 50.5 0.0 3.1e-13 50.0 0.0 1.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KUM63565.1 - 0.0021 17.2 0.1 0.0029 16.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KUM63565.1 - 0.003 17.8 0.1 0.0045 17.2 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 KUM63565.1 - 0.011 15.1 0.1 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 ThiF family RsgA_GTPase PF03193.16 KUM63565.1 - 0.18 11.7 1.2 0.6 10.0 0.6 1.9 1 1 1 2 2 2 0 RsgA GTPase MIT PF04212.18 KUM63567.1 - 0.0005 20.1 0.3 0.00082 19.4 0.3 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 KUM63567.1 - 0.0038 16.9 0.2 0.01 15.5 0.1 1.7 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 KUM63567.1 - 0.018 15.0 0.0 0.054 13.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat SnoaL_4 PF13577.6 KUM63568.1 - 7.2e-09 35.9 0.2 1.1e-08 35.3 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 KUM63568.1 - 0.0044 17.6 0.3 0.0074 16.9 0.3 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KUM63568.1 - 0.023 15.1 0.2 0.069 13.6 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 KUM63568.1 - 0.039 14.2 0.5 0.074 13.3 0.5 1.4 1 0 0 1 1 1 0 SnoaL-like domain MFS_1 PF07690.16 KUM63569.1 - 1.2e-33 116.6 29.8 1.7e-33 116.0 29.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KUM63569.1 - 3.5e-05 23.3 6.2 3.5e-05 23.3 6.2 2.7 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB YcxB PF14317.6 KUM63569.1 - 0.053 13.2 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 YcxB-like protein DUF373 PF04123.13 KUM63569.1 - 0.14 11.6 1.0 0.46 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF5136 PF17199.4 KUM63570.1 - 0.025 14.2 0.8 0.048 13.3 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF5136) HalOD1 PF18545.1 KUM63570.1 - 0.039 14.2 0.4 13 6.1 0.0 2.9 3 0 0 3 3 3 0 Halobacterial output domain 1 Ras PF00071.22 KUM63573.1 - 2e-54 183.6 1.3 2.2e-53 180.2 1.3 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KUM63573.1 - 3.4e-17 62.8 0.0 5.6e-16 58.8 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KUM63573.1 - 1.1e-06 28.3 0.1 3e-06 26.9 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KUM63573.1 - 2.5e-06 27.1 0.0 0.00026 20.5 0.1 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KUM63573.1 - 6.8e-05 22.8 0.2 0.25 11.2 0.1 2.4 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KUM63573.1 - 0.0017 18.4 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KUM63573.1 - 0.002 18.2 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KUM63573.1 - 0.01 15.4 0.1 0.049 13.2 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KUM63573.1 - 0.07 12.9 0.2 2.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CbiA PF01656.23 KUM63573.1 - 0.13 12.3 0.0 1.6 8.8 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.17 KUM63573.1 - 0.26 11.0 0.4 1.4 8.6 0.4 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein ParA PF10609.9 KUM63573.1 - 0.32 10.4 0.7 1.2 8.5 0.1 1.9 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase MoCF_biosynth PF00994.24 KUM63574.1 - 3.6e-36 124.0 0.0 5.6e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain Nuf2 PF03800.14 KUM63576.1 - 5.7e-44 149.6 0.2 1.7e-43 148.1 0.2 1.9 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KUM63576.1 - 1.1e-33 115.8 19.4 1.1e-33 115.8 19.4 3.7 3 1 0 3 3 3 1 Designed helical repeat protein 10 domain Bacillus_HBL PF05791.11 KUM63576.1 - 0.015 15.2 5.6 0.015 15.2 5.6 3.3 1 1 3 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) MHYT PF03707.16 KUM63577.1 - 5.3e-20 71.3 24.6 2.1e-09 37.4 0.6 5.0 5 1 0 5 5 5 4 Bacterial signalling protein N terminal repeat DUF4131 PF13567.6 KUM63577.1 - 7.8 6.1 11.2 2.4 7.8 4.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF775 PF05603.12 KUM63578.1 - 1.3e-61 207.6 0.0 1.5e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Thioredoxin PF00085.20 KUM63579.1 - 1.9e-28 98.5 0.1 2.3e-28 98.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KUM63579.1 - 1e-07 32.3 0.1 1e-06 29.1 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KUM63579.1 - 7.4e-06 25.8 0.0 1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KUM63579.1 - 1.6e-05 24.8 0.0 2.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KUM63579.1 - 6.3e-05 23.2 0.0 9.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KUM63579.1 - 0.00051 20.2 0.1 0.00082 19.5 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KUM63579.1 - 0.0029 17.3 0.1 0.0041 16.8 0.1 1.3 1 0 0 1 1 1 1 Redoxin Glutaredoxin PF00462.24 KUM63579.1 - 0.021 15.0 0.0 0.047 13.9 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin OST3_OST6 PF04756.13 KUM63579.1 - 0.032 13.6 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family LeuA_dimer PF08502.10 KUM63579.1 - 0.049 13.5 0.1 0.067 13.1 0.1 1.2 1 0 0 1 1 1 0 LeuA allosteric (dimerisation) domain PCYCGC PF13798.6 KUM63579.1 - 0.053 13.4 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif Acetyltransf_3 PF13302.7 KUM63580.1 - 2.6e-05 24.9 0.0 3.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KUM63580.1 - 0.00047 20.3 0.0 0.00084 19.5 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.25 KUM63581.1 - 6.2e-06 25.8 0.0 5.3e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM63581.1 - 0.00028 20.3 0.1 0.003 16.9 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Fe-S_assembly PF04384.13 KUM63581.1 - 0.092 13.4 0.0 5.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Iron-sulphur cluster assembly TPR_10 PF13374.6 KUM63582.1 - 2.6e-84 275.1 32.3 1.4e-07 31.2 0.1 12.4 12 0 0 12 12 12 12 Tetratricopeptide repeat TPR_12 PF13424.6 KUM63582.1 - 1.1e-61 205.1 60.1 3e-12 46.6 5.2 8.9 3 2 7 10 10 10 10 Tetratricopeptide repeat Pkinase PF00069.25 KUM63582.1 - 2.2e-51 174.8 0.0 3.2e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM63582.1 - 8e-29 100.7 0.0 1.2e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_1 PF00515.28 KUM63582.1 - 1.3e-12 46.9 10.3 0.57 10.1 0.1 9.4 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 KUM63582.1 - 3.9e-12 45.3 16.7 0.6 10.4 0.1 10.4 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_8 PF13181.6 KUM63582.1 - 4.8e-11 42.0 11.4 5.7 7.4 0.1 10.2 11 0 0 11 11 11 1 Tetratricopeptide repeat Kinase-like PF14531.6 KUM63582.1 - 1e-10 41.4 0.0 1.7e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF630 PF04783.12 KUM63582.1 - 1e-06 28.8 8.2 14 5.9 0.0 8.1 9 0 0 9 9 8 0 Protein of unknown function (DUF630) TPR_4 PF07721.14 KUM63582.1 - 3.3e-05 24.1 7.5 1.8 9.4 0.4 7.1 7 0 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM63582.1 - 0.00012 22.2 14.0 0.064 13.5 1.2 6.1 3 2 3 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 KUM63582.1 - 0.00013 22.4 20.8 2.2 8.7 0.5 8.1 4 1 4 8 8 8 1 Bacterial transcriptional activator domain TPR_7 PF13176.6 KUM63582.1 - 0.0008 19.3 19.4 2.7 8.2 0.2 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KUM63582.1 - 0.00083 20.0 17.9 0.028 15.1 0.5 5.6 5 1 1 6 6 5 3 Tetratricopeptide repeat APH PF01636.23 KUM63582.1 - 0.0069 16.3 0.1 0.0069 16.3 0.1 2.7 3 1 0 3 3 3 1 Phosphotransferase enzyme family HTH_43 PF09904.9 KUM63582.1 - 0.0071 16.3 0.1 3.1 7.8 0.0 3.5 2 1 0 3 3 3 1 Winged helix-turn helix COR PF16095.5 KUM63582.1 - 0.0091 15.8 4.0 12 5.6 0.0 5.7 4 1 2 6 6 6 0 C-terminal of Roc, COR, domain TPR_14 PF13428.6 KUM63582.1 - 0.01 16.6 26.4 30 5.8 0.0 9.7 11 1 1 12 12 10 0 Tetratricopeptide repeat Peptidase_M3_N PF08439.10 KUM63582.1 - 0.013 15.8 0.9 9.5 6.6 0.3 4.3 4 0 0 4 4 4 0 Oligopeptidase F TPR_19 PF14559.6 KUM63582.1 - 0.024 15.1 17.8 0.03 14.8 1.7 5.1 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KUM63582.1 - 0.12 12.8 5.6 92 3.8 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat RPN6_N PF18055.1 KUM63582.1 - 0.48 10.8 2.8 30 5.0 0.0 3.9 3 1 1 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain IF-2B PF01008.17 KUM63583.1 - 7.4e-49 166.5 0.0 9.2e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family OPT PF03169.15 KUM63585.1 - 2e-177 591.6 44.8 2.3e-177 591.4 44.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4743 PF15916.5 KUM63587.1 - 1.2e-13 51.1 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KUM63587.1 - 3.3e-11 43.4 0.0 5.8e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain 2OG-FeII_Oxy PF03171.20 KUM63588.1 - 1.4e-14 54.4 0.0 9.3e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KUM63588.1 - 5.5e-12 46.5 0.0 9.1e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal UPF0086 PF01868.16 KUM63589.1 - 5.2e-32 109.6 0.1 8.3e-32 109.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Cofilin_ADF PF00241.20 KUM63590.1 - 1.4e-21 76.5 0.1 1.6e-21 76.4 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DZR PF12773.7 KUM63591.1 - 0.028 14.4 28.9 0.13 12.3 12.1 3.6 2 2 1 3 3 3 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KUM63591.1 - 0.74 10.6 20.4 0.73 10.6 0.8 3.7 2 1 1 3 3 3 0 zinc-ribbon family Zn_ribbon_17 PF17120.5 KUM63591.1 - 4.2 7.1 28.7 2.1 8.1 3.6 3.2 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type PAXNEB PF05625.11 KUM63592.1 - 2.4e-117 392.2 0.0 2.7e-117 392.0 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RNA_pol_Rpb8 PF03870.15 KUM63593.1 - 2.1e-47 160.8 0.0 2.4e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KUM63593.1 - 9.6e-05 22.4 0.0 0.017 15.2 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G tRNA_int_endo PF01974.17 KUM63594.1 - 8.2e-14 51.4 0.0 1.6e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Adaptin_N PF01602.20 KUM63596.1 - 1.9e-97 327.1 0.0 3.6e-97 326.1 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KUM63596.1 - 2.9e-15 56.7 0.1 2.4e-13 50.4 0.0 3.5 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KUM63596.1 - 5.7e-09 36.2 0.0 0.0018 18.6 0.0 4.1 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KUM63596.1 - 4.7e-07 29.5 0.6 0.086 13.1 0.0 4.7 5 0 0 5 5 4 2 HEAT repeat Cohesin_HEAT PF12765.7 KUM63596.1 - 0.0013 19.0 0.1 0.018 15.3 0.0 2.6 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 KUM63596.1 - 0.017 15.6 1.8 30 5.3 0.0 4.7 5 0 0 5 5 5 0 HEAT-like repeat TFIIA PF03153.13 KUM63596.1 - 0.15 12.0 17.3 0.42 10.5 17.5 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec16 PF12932.7 KUM63596.1 - 0.6 10.7 4.0 13 6.4 0.9 2.7 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region YL1 PF05764.13 KUM63596.1 - 2.2 8.4 28.9 0.099 12.7 19.4 2.4 2 0 0 2 2 2 0 YL1 nuclear protein SpoIIIAH PF12685.7 KUM63596.1 - 4.3 7.1 13.9 38 4.0 0.1 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein BUD22 PF09073.10 KUM63596.1 - 5.4 6.3 21.9 9.4 5.5 14.5 2.7 3 0 0 3 3 3 0 BUD22 SDA1 PF05285.12 KUM63596.1 - 7.5 5.9 27.5 14 5.0 0.8 2.4 2 0 0 2 2 2 0 SDA1 TT_ORF2 PF02957.15 KUM63596.1 - 9.1 7.2 20.4 14 6.6 3.8 2.9 2 0 0 2 2 2 0 TT viral ORF2 Amidohydro_1 PF01979.20 KUM63597.1 - 2.3e-26 93.0 0.0 2.8e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KUM63597.1 - 5.4e-09 36.0 0.0 0.00029 20.4 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KUM63598.1 - 1.6e-08 34.3 0.0 1.6e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KUM63598.1 - 3.3e-08 33.4 0.0 3.3e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Metallophos PF00149.28 KUM63599.1 - 8.7e-36 124.3 0.2 1.2e-35 123.9 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KUM63599.1 - 0.077 13.4 0.3 0.22 12.0 0.3 1.8 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KUM63599.1 - 0.1 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Rho_GDI PF02115.17 KUM63600.1 - 5.3e-64 215.6 0.9 5.8e-64 215.4 0.9 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor KilA-N PF04383.13 KUM63601.1 - 0.00079 19.3 3.4 0.043 13.6 0.0 3.2 2 1 1 3 3 3 2 KilA-N domain U1snRNP70_N PF12220.8 KUM63601.1 - 0.008 16.8 6.2 0.008 16.8 6.2 3.3 4 1 0 4 4 4 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal BAF1_ABF1 PF04684.13 KUM63601.1 - 0.13 11.3 14.9 0.18 10.8 14.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Mitofilin PF09731.9 KUM63601.1 - 0.33 9.7 26.7 0.46 9.3 26.7 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Asp-B-Hydro_N PF05279.11 KUM63601.1 - 0.94 9.5 29.8 1.9 8.5 29.8 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF719 PF05334.13 KUM63601.1 - 6.5 6.9 18.8 3.4 7.8 5.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF719) NmrA PF05368.13 KUM63602.1 - 4.1e-33 114.9 0.0 5.4e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM63602.1 - 2.3e-18 66.8 0.0 2.8e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KUM63602.1 - 0.00025 20.6 0.0 0.00073 19.1 0.0 1.8 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KUM63602.1 - 0.001 18.1 0.0 0.0047 16.0 0.0 1.9 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KUM63602.1 - 0.0013 18.6 0.0 0.037 13.9 0.0 2.2 2 0 0 2 2 2 1 KR domain Semialdhyde_dh PF01118.24 KUM63602.1 - 0.0019 18.6 0.0 0.0057 17.1 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KUM63602.1 - 0.0055 15.9 0.0 0.028 13.6 0.0 2.1 2 1 0 2 2 2 1 Male sterility protein DapB_N PF01113.20 KUM63602.1 - 0.032 14.4 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 KUM63602.1 - 0.046 14.3 0.2 0.11 13.0 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_25 PF13649.6 KUM63603.1 - 2.3e-09 37.8 0.1 4.3e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM63603.1 - 9.7e-07 28.7 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM63603.1 - 1.2e-05 24.8 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KUM63603.1 - 4.8e-05 23.9 0.1 9.1e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM63603.1 - 6.4e-05 23.6 0.0 0.00013 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KUM63603.1 - 0.00031 20.3 0.1 0.00051 19.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CLP1_N PF16573.5 KUM63604.1 - 4.9e-33 113.2 0.0 9.6e-33 112.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 KUM63604.1 - 3e-29 102.2 0.0 1.7e-28 99.7 0.0 2.1 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KUM63604.1 - 2e-23 83.0 0.0 7e-23 81.3 0.0 1.9 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 KUM63604.1 - 0.00046 20.0 0.0 0.0031 17.3 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KUM63604.1 - 0.0011 19.1 0.0 0.0051 16.9 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_35 PF14516.6 KUM63604.1 - 0.02 13.8 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.6 KUM63604.1 - 0.032 13.9 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KUM63604.1 - 0.16 11.6 0.0 18 4.9 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Sgf11 PF08209.11 KUM63605.1 - 0.025 14.1 1.8 0.84 9.3 0.0 3.2 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) SNRNP27 PF08648.12 KUM63606.1 - 2e-26 91.8 3.6 3.4e-26 91.0 3.6 1.4 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins DAO PF01266.24 KUM63607.1 - 1.7e-68 231.8 0.5 2e-68 231.6 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM63607.1 - 8.2e-07 28.5 0.2 0.0055 16.0 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM63607.1 - 2.3e-06 27.8 0.2 5.1e-06 26.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KUM63607.1 - 3.1e-05 23.0 0.3 0.0014 17.6 0.2 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 KUM63607.1 - 0.00055 19.1 0.7 0.31 10.0 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KUM63607.1 - 0.00061 19.1 0.1 0.0011 18.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KUM63607.1 - 0.00063 20.3 0.3 0.0076 16.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM63607.1 - 0.00066 19.7 0.6 0.026 14.5 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Mqo PF06039.15 KUM63607.1 - 0.0092 14.6 0.0 0.076 11.6 0.0 1.9 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) MCRA PF06100.11 KUM63607.1 - 0.013 14.3 0.1 0.023 13.5 0.1 1.3 1 0 0 1 1 1 0 MCRA family FAD_oxidored PF12831.7 KUM63607.1 - 0.022 14.1 0.5 0.6 9.4 0.5 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 KUM63607.1 - 0.038 14.3 0.2 0.27 11.5 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain GIDA PF01134.22 KUM63607.1 - 0.083 12.0 0.8 7.9 5.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.16 KUM63607.1 - 0.15 11.7 0.0 0.42 10.3 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sugar_tr PF00083.24 KUM63608.1 - 4.7e-86 289.4 18.2 5.4e-86 289.2 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM63608.1 - 1.7e-17 63.4 26.9 5e-17 61.9 22.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-amylase PF00128.24 KUM63609.1 - 1.9e-96 323.6 1.8 2.6e-96 323.1 0.5 1.7 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KUM63609.1 - 2.2e-05 24.5 0.0 5.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Cellulase PF00150.18 KUM63609.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_114 PF03537.13 KUM63609.1 - 0.047 13.0 0.1 0.091 12.1 0.1 1.4 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 DUF3459 PF11941.8 KUM63609.1 - 0.18 12.1 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Elong_Iki1 PF10483.9 KUM63610.1 - 3.6e-102 341.9 0.0 4.1e-102 341.7 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF4246 PF14033.6 KUM63611.1 - 1.6e-172 574.7 0.0 2e-172 574.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 KUM63611.1 - 0.027 14.9 0.0 0.082 13.3 0.0 1.8 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase MFS_1 PF07690.16 KUM63612.1 - 1.3e-17 63.8 58.0 3.4e-12 46.0 39.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2976 PF11190.8 KUM63612.1 - 0.0051 16.6 1.7 0.032 14.0 0.4 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2976) Condensation PF00668.20 KUM63613.1 - 2.6e-103 346.2 0.0 3.7e-36 124.8 0.1 3.6 4 0 0 4 4 4 3 Condensation domain AMP-binding PF00501.28 KUM63613.1 - 4.6e-67 226.5 0.0 6.8e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KUM63613.1 - 1.8e-32 111.5 1.4 2.1e-10 40.8 0.0 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site WES_acyltransf PF03007.16 KUM63613.1 - 3.1e-05 23.9 0.5 0.0056 16.5 0.0 2.9 3 0 0 3 3 3 2 Wax ester synthase-like Acyl-CoA acyltransferase domain Transferase PF02458.15 KUM63613.1 - 0.017 13.8 0.0 0.099 11.3 0.0 2.1 2 0 0 2 2 2 0 Transferase family ABC_membrane PF00664.23 KUM63615.1 - 1.8e-84 283.7 32.0 3.4e-43 148.3 9.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KUM63615.1 - 9.9e-64 214.0 0.0 1.5e-31 109.7 0.0 3.1 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KUM63615.1 - 1.7e-15 57.1 1.6 2.9e-05 23.6 0.2 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KUM63615.1 - 6e-09 36.5 0.7 0.0053 17.1 0.4 3.5 2 2 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 KUM63615.1 - 1.3e-08 34.5 0.1 0.0019 17.9 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KUM63615.1 - 2.3e-08 34.4 0.1 0.031 14.5 0.0 4.0 3 1 0 4 4 4 2 AAA domain AAA_15 PF13175.6 KUM63615.1 - 4.3e-08 33.3 0.5 0.00048 19.9 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.9 KUM63615.1 - 1.3e-06 27.5 0.6 0.0066 15.3 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KUM63615.1 - 2.2e-06 27.7 0.0 0.021 14.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KUM63615.1 - 3.1e-05 24.6 5.9 0.0005 20.6 0.0 3.1 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.6 KUM63615.1 - 5.6e-05 23.3 0.0 0.53 10.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain G-alpha PF00503.20 KUM63615.1 - 0.00017 20.9 0.0 0.02 14.1 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_21 PF13304.6 KUM63615.1 - 0.00024 21.0 5.0 0.21 11.3 0.1 3.9 4 1 1 5 5 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 KUM63615.1 - 0.00028 20.9 0.0 2 8.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KUM63615.1 - 0.00034 20.4 0.0 2.2 8.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KUM63615.1 - 0.00086 19.6 0.0 1.5 9.1 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KUM63615.1 - 0.012 16.2 0.0 4.8 7.7 0.0 3.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KUM63615.1 - 0.013 14.7 0.0 0.18 11.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 KUM63615.1 - 0.014 15.8 0.0 9.5 6.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase SbcCD_C PF13558.6 KUM63615.1 - 0.017 15.4 3.3 9.1 6.6 0.1 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 KUM63615.1 - 0.021 14.8 0.0 6.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain DUF3987 PF13148.6 KUM63615.1 - 0.024 13.7 0.0 4.9 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_7 PF12775.7 KUM63615.1 - 0.024 14.1 0.0 6.5 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KUM63615.1 - 0.038 13.6 0.0 12 5.4 0.0 3.5 4 0 0 4 4 4 0 AAA domain MMR_HSR1 PF01926.23 KUM63615.1 - 0.042 13.9 0.0 1.7 8.7 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase Cytidylate_kin PF02224.18 KUM63615.1 - 0.048 13.4 0.0 4.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase AAA_PrkA PF08298.11 KUM63615.1 - 0.062 12.2 0.0 20 4.0 0.0 3.0 3 0 0 3 3 3 0 PrkA AAA domain DUF779 PF05610.11 KUM63615.1 - 0.075 13.3 0.1 2.8 8.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF779) APS_kinase PF01583.20 KUM63615.1 - 0.11 12.4 0.0 10 6.0 0.0 2.9 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_24 PF13479.6 KUM63615.1 - 0.15 11.8 0.2 7.8 6.2 0.0 3.0 4 0 0 4 4 4 0 AAA domain DUF87 PF01935.17 KUM63615.1 - 0.17 11.9 1.0 3.6 7.6 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain SPT_ssu-like PF11779.8 KUM63616.1 - 6.3e-23 80.2 3.2 1e-22 79.5 3.2 1.4 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Pet100 PF09803.9 KUM63617.1 - 4.4e-18 65.6 0.1 5.5e-18 65.2 0.1 1.2 1 0 0 1 1 1 1 Pet100 TMEM247 PF15444.6 KUM63617.1 - 0.011 15.8 1.2 0.013 15.5 1.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 D123 PF07065.14 KUM63618.1 - 5.1e-110 367.4 0.3 7.3e-110 366.9 0.3 1.3 1 0 0 1 1 1 1 D123 Vps51 PF08700.11 KUM63619.1 - 1.2e-14 54.1 0.0 1.8e-13 50.4 0.0 2.9 3 0 0 3 3 3 1 Vps51/Vps67 YbaB_DNA_bd PF02575.16 KUM63619.1 - 0.029 14.6 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family ECH_1 PF00378.20 KUM63620.1 - 1.1e-26 93.7 0.0 1.5e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KUM63620.1 - 4e-19 69.3 0.0 4.7e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase UvrD-helicase PF00580.21 KUM63621.1 - 5.1e-13 49.2 0.1 1.6e-08 34.5 0.0 3.4 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KUM63621.1 - 1.9e-07 30.8 0.0 0.00012 21.6 0.0 3.8 2 2 2 4 4 4 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KUM63621.1 - 1.3e-06 28.8 0.0 6.7e-05 23.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KUM63621.1 - 2.1e-06 27.4 0.1 0.0024 17.7 0.1 2.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain SNAP PF14938.6 KUM63621.1 - 9.5e-05 22.0 6.2 0.00019 21.0 4.4 2.4 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP AAA_16 PF13191.6 KUM63621.1 - 0.012 16.0 0.5 0.88 9.9 0.0 3.8 4 0 0 4 4 4 0 AAA ATPase domain TPR_7 PF13176.6 KUM63621.1 - 0.02 14.9 3.2 5.3 7.3 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_12 PF13087.6 KUM63621.1 - 0.024 14.3 0.1 0.58 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KUM63621.1 - 0.033 13.9 0.1 4 7.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain Clathrin PF00637.20 KUM63621.1 - 0.045 13.6 0.9 1.7 8.5 0.0 3.6 3 1 1 4 4 4 0 Region in Clathrin and VPS AAA_22 PF13401.6 KUM63621.1 - 0.058 13.7 0.4 1.2 9.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain YtzH PF14165.6 KUM63621.1 - 0.079 13.4 0.4 0.34 11.3 0.4 2.1 1 0 0 1 1 1 0 YtzH-like protein NAPRTase_N PF17767.1 KUM63621.1 - 0.16 12.4 1.0 3.2 8.1 0.3 2.6 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain TPR_1 PF00515.28 KUM63621.1 - 0.34 10.8 8.3 4.1 7.4 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_23 PF13476.6 KUM63621.1 - 2.3 8.7 4.6 13 6.2 0.1 2.8 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.17 KUM63621.1 - 4.2 7.7 11.0 6.9 7.1 0.2 5.5 5 2 1 6 6 6 0 Tetratricopeptide repeat DUF1640 PF07798.11 KUM63622.1 - 1.5e-40 139.1 6.0 2.2e-40 138.6 6.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) LCIB_C_CA PF18599.1 KUM63622.1 - 0.23 10.8 1.1 0.4 9.9 1.1 1.3 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases PIN_8 PF18476.1 KUM63622.1 - 0.49 10.2 3.9 1 9.2 3.9 1.5 1 0 0 1 1 1 0 PIN like domain Longin PF13774.6 KUM63623.1 - 6.2e-26 90.3 0.7 9.8e-26 89.6 0.7 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KUM63623.1 - 3e-14 52.6 0.0 6.2e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin SLM4 PF16818.5 KUM63623.1 - 0.037 14.0 0.3 0.34 10.9 0.0 2.1 1 1 1 2 2 2 0 Protein SLM4 EMP24_GP25L PF01105.24 KUM63623.1 - 0.15 12.0 0.5 0.3 11.0 0.2 1.6 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD ASXH PF13919.6 KUM63624.1 - 8.3e-38 129.5 1.8 8.3e-38 129.5 1.8 1.8 2 0 0 2 2 2 1 Asx homology domain AT_hook PF02178.19 KUM63624.1 - 1 9.5 11.3 3.4 7.9 11.3 2.0 1 0 0 1 1 1 0 AT hook motif Transp_cyt_pur PF02133.15 KUM63625.1 - 8.7e-23 80.8 41.3 1.3e-22 80.2 41.3 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HEAT_2 PF13646.6 KUM63626.1 - 1.2e-08 35.2 4.1 0.012 16.0 0.0 5.9 6 1 1 7 7 7 4 HEAT repeats HEAT PF02985.22 KUM63626.1 - 1.5e-06 27.9 9.6 1.1 9.7 0.0 8.3 9 0 0 9 9 9 3 HEAT repeat Nuc_recep-AF1 PF11825.8 KUM63626.1 - 0.091 12.8 0.1 0.34 11.0 0.1 2.0 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 HEAT_EZ PF13513.6 KUM63626.1 - 0.82 10.3 14.0 2.8 8.5 0.0 7.5 8 0 0 8 8 8 0 HEAT-like repeat CENP-I PF07778.11 KUM63628.1 - 2.5e-42 145.3 0.1 9.6e-42 143.4 0.1 1.8 1 1 0 1 1 1 1 Mis6 Transcrip_reg PF01709.20 KUM63629.1 - 3.8e-69 232.8 0.4 4.4e-69 232.6 0.4 1.0 1 0 0 1 1 1 1 Transcriptional regulator NapD PF03927.13 KUM63629.1 - 0.087 12.9 1.6 8.5 6.5 0.0 3.2 2 1 1 3 3 3 0 NapD protein Dicistro_VP4 PF11492.8 KUM63630.1 - 0.0033 17.4 0.2 1.5 8.9 0.0 2.2 2 0 0 2 2 2 2 Cricket paralysis virus, VP4 Lipase_GDSL_3 PF14606.6 KUM63630.1 - 0.046 13.9 0.0 8.8 6.4 0.0 2.0 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family MetJ PF01340.20 KUM63630.1 - 0.19 11.7 0.0 16 5.6 0.0 2.1 2 0 0 2 2 2 0 Met Apo-repressor, MetJ IBR PF01485.21 KUM63631.1 - 1.7e-18 66.6 42.6 3.4e-15 56.0 4.9 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 KUM63631.1 - 7.3e-17 61.7 0.0 1.2e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain zf-RING_5 PF14634.6 KUM63631.1 - 0.0019 18.1 10.5 0.0019 18.1 10.5 4.0 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_11 PF17123.5 KUM63631.1 - 0.0028 17.4 5.4 0.0028 17.4 5.4 2.5 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_2 PF13639.6 KUM63631.1 - 0.0059 16.9 10.2 0.0059 16.9 10.2 4.3 3 1 1 4 4 4 1 Ring finger domain CRT10 PF08728.10 KUM63632.1 - 3.1e-20 72.0 0.0 1.7e-11 43.1 0.0 2.2 2 0 0 2 2 2 2 CRT10 MMtag PF10159.9 KUM63633.1 - 1.4e-33 115.0 3.5 1.4e-33 115.0 3.5 2.6 2 1 0 2 2 2 1 Multiple myeloma tumor-associated Glyco_hydro_63 PF03200.16 KUM63634.1 - 1.2e-175 585.1 4.3 1.9e-174 581.0 4.3 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KUM63634.1 - 1.1e-88 297.1 0.0 2.9e-88 295.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KUM63634.1 - 0.033 13.0 4.6 0.13 11.1 4.6 2.1 1 1 0 1 1 1 0 Trehalase Nif11 PF07862.11 KUM63634.1 - 0.078 13.3 0.1 0.71 10.2 0.1 2.4 2 0 0 2 2 2 0 Nif11 domain UreD PF01774.17 KUM63635.1 - 1e-68 231.5 0.0 1.2e-68 231.2 0.0 1.0 1 0 0 1 1 1 1 UreD urease accessory protein Amidohydro_1 PF01979.20 KUM63636.1 - 8.1e-68 229.2 0.3 1.5e-67 228.4 0.3 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KUM63636.1 - 2.7e-52 176.2 1.2 6.1e-52 175.1 1.2 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KUM63636.1 - 2.3e-38 130.1 0.0 4.5e-38 129.2 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 KUM63636.1 - 2.6e-14 53.3 0.1 5.5e-14 52.3 0.1 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KUM63636.1 - 4.4e-11 42.9 0.0 9.8e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF3402 PF11882.8 KUM63637.1 - 1.7e-194 647.3 0.0 2.4e-194 646.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KUM63637.1 - 5e-88 295.0 0.0 7.7e-88 294.4 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein TbpB_C PF17483.2 KUM63637.1 - 0.06 13.7 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B PAP2 PF01569.21 KUM63638.1 - 3.1e-15 56.1 4.8 3.1e-15 56.1 4.8 2.1 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 KUM63638.1 - 8e-05 22.8 0.2 0.0059 16.7 0.1 2.2 1 1 1 2 2 2 2 Divergent PAP2 family DUF4131 PF13567.6 KUM63638.1 - 3.3 7.4 8.0 5.3 6.7 5.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Arylsulfotrans PF05935.11 KUM63639.1 - 1.3e-12 47.4 0.2 1.4e-07 30.8 0.2 3.3 2 1 1 3 3 3 2 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 KUM63639.1 - 6.1e-12 45.5 0.0 1.9e-11 43.9 0.0 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.6 KUM63639.1 - 0.0014 18.2 0.2 0.028 14.0 0.2 2.6 2 1 0 2 2 2 1 PQQ-like domain adh_short PF00106.25 KUM63640.1 - 1.6e-24 86.4 0.0 3.8e-24 85.2 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM63640.1 - 1.8e-16 60.4 0.0 9e-16 58.1 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM63640.1 - 0.00014 21.8 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 KR domain CLPTM1 PF05602.12 KUM63641.1 - 3.9e-160 533.6 0.0 4.5e-160 533.3 0.0 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Trep_Strep PF09605.10 KUM63642.1 - 0.13 12.2 3.7 0.21 11.5 3.7 1.3 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Ferritin_2 PF13668.6 KUM63643.1 - 4.2e-17 62.6 0.2 7.7e-17 61.8 0.2 1.4 1 0 0 1 1 1 1 Ferritin-like domain SGL PF08450.12 KUM63644.1 - 3.1e-05 23.7 0.1 5.9e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 KUM63644.1 - 0.041 13.1 0.1 0.58 9.4 0.0 2.5 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller EthD PF07110.11 KUM63645.1 - 0.0046 18.1 0.0 0.007 17.5 0.0 1.3 1 0 0 1 1 1 1 EthD domain ABM PF03992.16 KUM63645.1 - 0.091 12.9 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase DUF4112 PF13430.6 KUM63646.1 - 3e-34 117.5 0.4 3.8e-34 117.1 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DCP2 PF05026.13 KUM63647.1 - 6e-31 106.6 1.8 1.1e-30 105.8 1.8 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KUM63647.1 - 3e-18 66.1 0.1 5.6e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain Lung_7-TM_R PF06814.13 KUM63648.1 - 5.1e-69 232.8 17.5 6e-69 232.5 17.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor CTU2 PF10288.9 KUM63649.1 - 1.2e-10 41.6 0.2 6.2e-08 32.9 0.0 2.6 1 1 1 2 2 2 2 Cytoplasmic tRNA 2-thiolation protein 2 DUF1308 PF07000.11 KUM63650.1 - 4.8e-11 42.9 0.0 6.2e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) ASD2 PF08687.11 KUM63650.1 - 0.013 15.0 0.5 0.027 14.0 0.5 1.4 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 DUF5614 PF18474.1 KUM63650.1 - 0.025 13.9 0.0 1.3 8.3 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5614) APH PF01636.23 KUM63651.1 - 0.00067 19.7 0.0 0.00095 19.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Mei4 PF13971.6 KUM63652.1 - 0.0082 15.7 5.6 0.031 13.8 5.6 2.1 1 1 0 1 1 1 1 Meiosis-specific protein Mei4 DUF4407 PF14362.6 KUM63652.1 - 0.08 12.3 6.6 0.04 13.3 4.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Amidohydro_2 PF04909.14 KUM63653.1 - 1.1e-24 87.8 0.1 3.1e-24 86.2 0.1 1.8 1 1 0 1 1 1 1 Amidohydrolase DIOX_N PF14226.6 KUM63654.1 - 2e-24 86.6 0.0 3.7e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KUM63654.1 - 3e-17 63.0 0.0 6e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HSBP1 PF06825.12 KUM63655.1 - 1.6e-18 66.2 0.2 2.5e-18 65.6 0.2 1.3 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.9 KUM63655.1 - 0.0027 17.5 0.6 0.018 14.9 0.6 2.1 1 1 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.12 KUM63655.1 - 0.025 15.0 0.2 0.047 14.2 0.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Apolipoprotein PF01442.18 KUM63655.1 - 0.027 14.3 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KUM63655.1 - 0.036 14.1 0.2 0.05 13.7 0.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vinculin PF01044.19 KUM63655.1 - 0.05 11.8 0.1 0.058 11.6 0.1 1.0 1 0 0 1 1 1 0 Vinculin family Snapin_Pallidin PF14712.6 KUM63655.1 - 0.081 13.4 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Snapin/Pallidin DUF4164 PF13747.6 KUM63655.1 - 0.082 13.2 0.2 0.15 12.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Ebp2 PF05890.12 KUM63656.1 - 2.1e-93 312.7 15.1 2.1e-93 312.7 15.1 2.0 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 SRP-alpha_N PF04086.13 KUM63656.1 - 1.6 8.6 37.9 3.6 7.4 19.6 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF2052 PF09747.9 KUM63656.1 - 1.9 8.5 28.7 1.7 8.7 16.4 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Myc_N PF01056.18 KUM63656.1 - 3.3 7.5 21.1 0.13 12.1 13.5 2.1 2 0 0 2 2 2 0 Myc amino-terminal region B277 PF17623.2 KUM63656.1 - 8.9 5.3 8.1 19 4.2 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function zf-MYND PF01753.18 KUM63657.1 - 1.9e-07 31.1 20.7 3.7e-07 30.1 20.7 1.5 1 0 0 1 1 1 1 MYND finger S_4TM PF18159.1 KUM63657.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain zf-TAZ PF02135.16 KUM63657.1 - 7.9 7.0 13.3 14 6.2 13.3 1.4 1 0 0 1 1 1 0 TAZ zinc finger DIOX_N PF14226.6 KUM63658.1 - 2.3e-19 70.3 0.0 3.4e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KUM63658.1 - 2.1e-11 44.2 0.0 7.2e-11 42.5 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Thioredoxin PF00085.20 KUM63659.1 - 4.2e-57 190.5 0.2 5.2e-29 100.3 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin ERp29 PF07749.12 KUM63659.1 - 3.5e-22 79.1 0.6 9e-22 77.8 0.6 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KUM63659.1 - 5.3e-18 65.5 0.0 1.5e-07 31.8 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KUM63659.1 - 5.3e-15 55.5 0.0 2.3e-07 30.4 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KUM63659.1 - 1.8e-11 44.1 0.0 7.7e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KUM63659.1 - 1.3e-08 35.1 0.0 0.0019 18.5 0.0 3.4 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 KUM63659.1 - 3.3e-08 33.5 0.0 0.0069 16.3 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family TraF PF13728.6 KUM63659.1 - 4.2e-07 30.0 0.0 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 KUM63659.1 - 1.8e-06 27.7 0.2 0.037 13.7 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.6 KUM63659.1 - 4.9e-05 23.3 0.4 1.4 8.8 0.0 3.5 3 1 1 4 4 4 2 Thioredoxin-like domain HyaE PF07449.11 KUM63659.1 - 0.00023 21.1 0.1 0.19 11.7 0.0 2.8 2 1 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KUM63659.1 - 0.00066 19.5 0.0 0.3 10.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.24 KUM63659.1 - 0.0093 16.2 2.0 2.8 8.2 0.1 3.2 3 2 0 3 3 3 1 Glutaredoxin DSBA PF01323.20 KUM63659.1 - 0.018 14.9 1.6 12 5.6 0.0 3.7 3 2 1 4 4 4 0 DSBA-like thioredoxin domain DUF836 PF05768.14 KUM63659.1 - 0.089 13.2 0.0 0.77 10.2 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) SLATT_4 PF18186.1 KUM63659.1 - 0.11 12.1 0.2 0.19 11.3 0.2 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 Thioredoxin_4 PF13462.6 KUM63659.1 - 0.21 11.7 3.0 37 4.4 0.0 3.7 2 2 2 4 4 4 0 Thioredoxin Phosducin PF02114.16 KUM63660.1 - 4.6e-16 58.6 0.0 1.2e-14 53.9 0.0 2.2 1 1 0 1 1 1 1 Phosducin Clathrin_lg_ch PF01086.17 KUM63660.1 - 0.027 14.5 3.7 0.041 13.9 3.7 1.3 1 0 0 1 1 1 0 Clathrin light chain FAM176 PF14851.6 KUM63660.1 - 4.1 7.1 5.0 1.6 8.4 0.9 2.0 1 1 1 2 2 2 0 FAM176 family CoA_transf_3 PF02515.17 KUM63661.1 - 2.6e-40 138.7 0.2 6.4e-40 137.4 0.1 1.7 2 0 0 2 2 2 1 CoA-transferase family III ABC_tran PF00005.27 KUM63662.1 - 1.9e-24 86.7 0.0 2.5e-13 50.7 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KUM63662.1 - 2e-14 54.1 6.7 7e-08 32.6 0.2 3.2 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KUM63662.1 - 4.2e-07 30.1 0.0 0.0076 16.5 0.0 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KUM63662.1 - 0.0044 16.7 0.1 0.0089 15.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KUM63662.1 - 0.0077 15.7 0.0 0.67 9.3 0.0 2.5 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KUM63662.1 - 0.0089 16.6 0.2 0.015 15.8 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KUM63662.1 - 0.02 15.1 0.1 0.52 10.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KUM63662.1 - 0.097 12.6 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KUM63662.1 - 0.15 11.2 0.0 0.41 9.8 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 KUM63662.1 - 0.17 11.6 0.1 20 4.9 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein Ploopntkinase1 PF18748.1 KUM63662.1 - 0.2 11.2 0.0 0.39 10.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 EthD PF07110.11 KUM63663.1 - 1.4e-11 45.4 0.2 1.8e-11 45.0 0.2 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KUM63663.1 - 0.00039 20.8 0.4 0.00094 19.6 0.4 1.6 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase WD40 PF00400.32 KUM63664.1 - 3.9e-28 97.1 5.5 2.1e-06 28.3 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM63664.1 - 3.3e-08 33.7 0.1 0.79 10.1 0.0 4.8 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KUM63664.1 - 0.00049 18.8 0.0 0.6 8.6 0.0 3.7 3 1 1 4 4 4 1 Cytochrome D1 heme domain PD40 PF07676.12 KUM63664.1 - 0.012 15.6 0.0 25 5.0 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KUM63664.1 - 0.04 12.9 0.0 2 7.3 0.0 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KUM63664.1 - 0.065 13.1 0.0 0.34 10.8 0.0 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 KUM63664.1 - 0.18 11.8 0.0 22 5.2 0.0 3.8 3 2 2 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Ribonuc_red_sm PF00268.21 KUM63665.1 - 2e-122 408.0 0.8 2.4e-122 407.8 0.8 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain RE_XcyI PF09571.10 KUM63665.1 - 0.025 13.9 0.1 3.6 6.8 0.0 2.1 2 0 0 2 2 2 0 XcyI restriction endonuclease TruB_N PF01509.18 KUM63666.1 - 8.5e-46 156.0 0.1 4.2e-45 153.8 0.0 2.2 2 1 1 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KUM63666.1 - 1.7e-06 28.1 0.0 3.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Baculo_PP31 PF05311.11 KUM63666.1 - 0.066 12.7 0.0 0.15 11.5 0.0 1.5 1 1 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Gas_vesicle_C PF01304.17 KUM63666.1 - 0.98 9.5 4.7 4.7 7.3 2.0 2.5 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain SRP9-21 PF05486.12 KUM63668.1 - 3.4e-31 107.5 0.8 4.5e-31 107.1 0.8 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DNMT1-RFD PF12047.8 KUM63669.1 - 6.6e-05 23.0 0.0 0.00018 21.6 0.0 1.7 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Ycf1 PF05758.12 KUM63669.1 - 0.47 8.2 1.4 0.68 7.7 1.4 1.1 1 0 0 1 1 1 0 Ycf1 NOA36 PF06524.12 KUM63669.1 - 4.1 6.6 13.5 1.2 8.4 2.3 2.3 2 0 0 2 2 2 0 NOA36 protein OHCU_decarbox PF09349.10 KUM63670.1 - 1.3e-30 106.9 0.0 1.4e-30 106.8 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase GCV_T PF01571.21 KUM63671.1 - 0.0002 20.8 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain WD40 PF00400.32 KUM63672.1 - 1.2e-12 48.1 2.6 0.0002 22.1 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM63672.1 - 2.3e-06 27.8 0.0 0.054 13.8 0.0 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KUM63672.1 - 0.044 12.1 0.0 0.07 11.4 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz TruB_C PF09142.11 KUM63672.1 - 0.096 12.5 0.1 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal PD40 PF07676.12 KUM63672.1 - 0.1 12.6 0.2 63 3.7 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Mito_carr PF00153.27 KUM63673.1 - 3.8e-54 180.6 3.8 8.1e-19 67.3 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MotA_ExbB PF01618.16 KUM63673.1 - 0.074 12.8 0.0 0.25 11.1 0.0 1.9 1 1 0 1 1 1 0 MotA/TolQ/ExbB proton channel family MscL PF01741.18 KUM63674.1 - 3.8e-18 65.9 0.2 5.3e-18 65.5 0.2 1.2 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf-ribbon_3 PF13248.6 KUM63674.1 - 0.0036 16.7 1.8 0.0056 16.0 1.8 1.3 1 0 0 1 1 1 1 zinc-ribbon domain UPF0547 PF10571.9 KUM63674.1 - 0.015 15.3 1.4 0.026 14.6 1.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-Di19 PF05605.12 KUM63674.1 - 0.089 13.1 0.3 0.17 12.2 0.3 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.19 KUM63674.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-LSD1 PF06943.12 KUM63674.1 - 0.47 10.3 4.6 4.5 7.2 0.7 2.3 2 0 0 2 2 2 0 LSD1 zinc finger AMP-binding PF00501.28 KUM63675.1 - 4.7e-67 226.4 0.0 6.4e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM63675.1 - 2.2e-16 60.6 0.0 5.4e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.25 KUM63677.1 - 8.2e-34 116.8 0.1 2.1e-33 115.4 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM63677.1 - 3.8e-31 108.4 0.3 1.3e-29 103.4 0.3 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM63677.1 - 3.6e-08 33.5 1.2 6.3e-08 32.7 0.2 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KUM63677.1 - 0.00084 18.6 0.1 0.0014 17.8 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KUM63677.1 - 0.0029 17.9 0.2 0.0051 17.1 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KUM63677.1 - 0.012 14.7 0.1 0.024 13.7 0.1 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.10 KUM63677.1 - 0.026 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KUM63677.1 - 0.047 13.1 0.1 0.098 12.1 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KUM63677.1 - 0.064 13.3 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Response_reg PF00072.24 KUM63678.1 - 8.6e-24 83.9 0.3 2e-23 82.7 0.3 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KUM63678.1 - 3.8e-17 62.8 0.0 1.4e-16 61.0 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KUM63678.1 - 4.2e-11 42.7 0.1 1.4e-10 41.0 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KUM63678.1 - 0.055 13.8 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 GAF domain DUF1002 PF06207.11 KUM63678.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) GAF PF01590.26 KUM63678.1 - 0.11 13.1 0.0 1.4 9.6 0.0 2.6 2 1 0 2 2 2 0 GAF domain SdpI PF13630.6 KUM63679.1 - 0.05 13.7 0.4 0.05 13.7 0.4 2.8 1 1 1 2 2 2 0 SdpI/YhfL protein family FtsX PF02687.21 KUM63679.1 - 0.91 10.0 6.5 0.61 10.6 0.2 2.7 2 0 0 2 2 2 0 FtsX-like permease family GpcrRhopsn4 PF10192.9 KUM63679.1 - 1.1 8.6 9.0 0.06 12.7 3.5 1.6 2 0 0 2 2 2 0 Rhodopsin-like GPCR transmembrane domain CcmF_C PF16327.5 KUM63679.1 - 3.1 7.0 12.8 0.094 12.0 5.5 1.9 1 1 1 2 2 2 0 Cytochrome c-type biogenesis protein CcmF C-terminal Syndecan PF01034.20 KUM63679.1 - 7.6 6.5 6.5 1.2 9.1 0.3 2.5 2 0 0 2 2 2 0 Syndecan domain DnaJ PF00226.31 KUM63680.1 - 9.4e-20 70.5 2.2 1.5e-19 69.8 1.1 2.0 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.22 KUM63680.1 - 0.031 14.1 0.1 0.11 12.3 0.1 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MKT1_C PF12246.8 KUM63681.1 - 2.9e-78 262.4 0.0 5.3e-78 261.6 0.0 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KUM63681.1 - 1.9e-29 101.9 0.0 4.2e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KUM63681.1 - 2.4e-05 24.7 0.0 5.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KUM63681.1 - 0.00011 22.5 0.0 0.00023 21.4 0.0 1.5 1 0 0 1 1 1 1 XPG I-region DUF3665 PF12427.8 KUM63681.1 - 0.13 12.0 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase WD40 PF00400.32 KUM63683.1 - 6.9e-37 124.8 19.0 1.1e-05 26.1 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM63683.1 - 1.7e-15 57.0 0.0 0.00038 20.7 0.0 5.1 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KUM63683.1 - 0.00013 22.0 0.0 0.15 12.0 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KUM63683.1 - 0.001 18.4 0.0 0.041 13.2 0.0 2.9 2 1 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 KUM63683.1 - 0.14 11.1 0.2 18 4.2 0.0 3.1 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CCDC106 PF15794.5 KUM63684.1 - 0.3 10.8 4.3 0.55 9.9 4.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SRP-alpha_N PF04086.13 KUM63684.1 - 2.6 7.9 10.5 0.32 10.9 6.6 1.4 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal C2 PF00168.30 KUM63685.1 - 3.3e-29 101.2 0.0 9.5e-17 61.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain Fungal_trans PF04082.18 KUM63686.1 - 1.3e-19 70.3 0.7 2.2e-19 69.5 0.7 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KUM63687.1 - 0.0014 17.7 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM63688.1 - 1.1 9.4 7.9 2 8.6 7.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain EF-hand_7 PF13499.6 KUM63689.1 - 2.4e-14 53.5 0.3 6.8e-08 32.9 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KUM63689.1 - 3.9e-14 51.0 2.1 1.7e-05 24.0 0.1 3.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KUM63689.1 - 1.9e-12 46.0 4.3 1.7e-05 24.3 0.2 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KUM63689.1 - 1.1e-10 41.1 2.1 5.8e-08 32.5 0.1 2.7 2 1 1 3 3 3 2 EF-hand domain pair DUF3572 PF12096.8 KUM63689.1 - 0.028 14.6 0.1 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) EF-hand_4 PF12763.7 KUM63689.1 - 0.091 12.7 0.0 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 KUM63689.1 - 2 8.1 6.9 6.9 6.3 0.1 3.0 3 0 0 3 3 3 0 EF hand Reprolysin_5 PF13688.6 KUM63690.1 - 2e-58 197.8 9.1 2e-58 197.8 9.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KUM63690.1 - 1.9e-47 161.6 4.1 4.1e-47 160.5 4.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KUM63690.1 - 1.3e-40 139.4 5.3 1.3e-40 139.4 5.3 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KUM63690.1 - 1.3e-16 61.1 35.5 1.3e-16 61.1 35.5 4.5 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 KUM63690.1 - 1.3e-08 35.4 0.7 8.1e-08 32.8 0.1 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 KUM63690.1 - 0.00025 21.3 0.0 0.00053 20.2 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Mid2 PF04478.12 KUM63690.1 - 0.00087 19.1 1.1 0.0018 18.1 0.2 2.0 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor ADAM_CR_2 PF17771.1 KUM63690.1 - 0.0029 18.1 10.4 0.0029 18.1 10.4 4.8 1 1 2 3 3 3 1 ADAM cysteine-rich domain LapA_dom PF06305.11 KUM63690.1 - 0.15 11.9 1.7 0.3 10.9 0.3 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Peptidase_M10 PF00413.24 KUM63690.1 - 0.19 11.6 0.3 0.35 10.7 0.3 1.6 1 1 0 1 1 1 0 Matrixin IMS PF00817.20 KUM63691.1 - 2.6e-36 124.9 0.0 4.7e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KUM63691.1 - 1.6e-17 64.2 0.1 4e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KUM63691.1 - 9.9e-06 25.6 0.0 2.6e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif HHH_5 PF14520.6 KUM63691.1 - 0.0021 18.6 0.0 0.0057 17.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain BAF PF02961.14 KUM63691.1 - 0.15 12.5 0.0 1.6 9.2 0.0 2.3 1 1 1 2 2 2 0 Barrier to autointegration factor Say1_Mug180 PF10340.9 KUM63692.1 - 0.082 11.8 0.0 0.082 11.8 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Alk_phosphatase PF00245.20 KUM63693.1 - 3.5e-67 227.2 1.4 7.2e-67 226.1 1.4 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 KUM63693.1 - 8.3e-08 32.0 6.7 2.4e-06 27.2 6.7 2.5 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KUM63693.1 - 7.6e-06 25.8 0.4 1.5e-05 24.8 0.4 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KUM63693.1 - 0.00085 18.0 0.3 0.0014 17.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KUM63693.1 - 0.01 15.3 0.5 0.022 14.1 0.5 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF1501 PF07394.12 KUM63693.1 - 0.034 13.2 0.2 0.057 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) HHH_3 PF12836.7 KUM63693.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Cu_amine_oxidN2 PF02727.16 KUM63694.1 - 0.13 12.5 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain zf-MYND PF01753.18 KUM63694.1 - 1.4 9.1 6.5 4.1 7.6 6.5 1.8 1 0 0 1 1 1 0 MYND finger MgsA_C PF12002.8 KUM63695.1 - 9.6e-57 191.6 0.0 1.7e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KUM63695.1 - 3.9e-23 81.6 0.8 1.2e-22 80.1 0.3 2.0 2 0 0 2 2 2 1 AAA C-terminal domain AAA PF00004.29 KUM63695.1 - 1.1e-12 48.6 0.0 2.5e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KUM63695.1 - 3.9e-09 36.4 0.0 7.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KUM63695.1 - 1.7e-05 24.3 0.0 0.14 11.6 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KUM63695.1 - 5.6e-05 22.9 0.0 0.0026 17.5 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KUM63695.1 - 7.1e-05 22.8 0.0 0.0012 18.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KUM63695.1 - 0.00032 21.1 0.3 0.094 13.1 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_3 PF07726.11 KUM63695.1 - 0.0017 18.2 0.0 0.0058 16.5 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KUM63695.1 - 0.0029 17.9 0.0 0.0088 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KUM63695.1 - 0.0062 15.7 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KUM63695.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KUM63695.1 - 0.013 15.5 0.1 2.1 8.3 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 KUM63695.1 - 0.021 14.9 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 KUM63695.1 - 0.028 14.1 0.1 0.063 13.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 KUM63695.1 - 0.031 13.5 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain PIF1 PF05970.14 KUM63695.1 - 0.039 13.1 0.1 0.062 12.5 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_18 PF13238.6 KUM63695.1 - 0.09 13.3 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KUM63695.1 - 0.093 12.5 0.1 5.6 6.8 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KUM63695.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KUM63695.1 - 0.2 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Aminotran_1_2 PF00155.21 KUM63696.1 - 1.3e-67 228.5 0.0 1.5e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KUM63696.1 - 0.017 13.7 0.0 0.027 13.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KUM63696.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Ald_Xan_dh_C2 PF02738.18 KUM63697.1 - 1.5e-202 673.9 1.4 2.1e-202 673.5 1.4 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KUM63697.1 - 1.2e-48 165.1 0.0 2.4e-48 164.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 KUM63697.1 - 1.6e-32 111.7 0.1 6.6e-32 109.8 0.1 2.1 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 KUM63697.1 - 4.5e-32 110.7 0.0 1e-31 109.5 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 KUM63697.1 - 1.8e-11 43.9 0.0 4.1e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Baculo_PEP_C PF04513.12 KUM63698.1 - 0.0064 16.5 4.3 0.079 13.0 0.3 2.8 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus ETRAMP PF09716.10 KUM63698.1 - 1.5 8.9 7.4 49 4.1 0.3 4.1 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) Homeobox_KN PF05920.11 KUM63699.1 - 1.1e-16 60.4 1.9 2.7e-16 59.2 1.9 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KUM63699.1 - 2.4e-07 30.5 4.2 5.1e-07 29.5 4.2 1.6 1 0 0 1 1 1 1 Homeodomain zf-C2H2 PF00096.26 KUM63699.1 - 3.6e-07 30.3 18.9 0.13 12.8 5.6 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM63699.1 - 0.0014 19.3 22.2 0.12 13.2 6.0 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger Collectrin PF16959.5 KUM63699.1 - 0.073 12.8 0.1 0.79 9.5 0.0 2.1 2 0 0 2 2 2 0 Renal amino acid transporter TilS PF09179.11 KUM63699.1 - 0.095 13.2 0.1 1.1 9.8 0.1 2.4 2 0 0 2 2 2 0 TilS substrate binding domain Fer2_2 PF01799.20 KUM63699.1 - 0.29 11.2 1.7 25 5.0 0.0 3.3 3 0 0 3 3 3 0 [2Fe-2S] binding domain FANCL_C PF11793.8 KUM63699.1 - 0.62 10.3 4.7 1.3 9.3 2.9 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C2H2_2 PF12756.7 KUM63699.1 - 2.2 8.7 6.4 27 5.2 3.6 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Aa_trans PF01490.18 KUM63700.1 - 1.8e-40 138.9 29.5 2.3e-40 138.6 29.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.6 KUM63700.1 - 0.12 12.2 1.3 11 6.0 0.1 3.1 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase SID-1_RNA_chan PF13965.6 KUM63700.1 - 4.1 5.7 9.8 6.4 5.1 9.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NAD_binding_10 PF13460.6 KUM63701.1 - 9.5e-18 64.7 0.0 1.2e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KUM63701.1 - 0.0093 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Phage-MuB_C PF09077.11 KUM63701.1 - 0.18 11.7 0.2 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Mu B transposition protein, C terminal Fungal_trans PF04082.18 KUM63702.1 - 7.3e-16 58.0 0.0 1.3e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM63702.1 - 2e-08 34.2 13.9 3.4e-08 33.5 13.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cys_Met_Meta_PP PF01053.20 KUM63703.1 - 8.5e-116 386.6 0.0 9.6e-116 386.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KUM63703.1 - 4.1e-07 29.5 0.1 6e-07 29.0 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KUM63703.1 - 0.0019 17.6 0.1 0.0026 17.2 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KUM63703.1 - 0.046 12.7 0.1 0.06 12.3 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class-V Peptidase_M20 PF01546.28 KUM63704.1 - 1.6e-34 119.4 0.0 2.8e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KUM63704.1 - 9.8e-06 25.4 0.0 3.6e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.14 KUM63704.1 - 0.00017 21.5 0.0 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain AMP-binding PF00501.28 KUM63705.1 - 2.6e-88 296.4 0.1 3.4e-88 296.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM63705.1 - 2.3e-26 92.6 1.9 4.4e-26 91.7 0.6 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KUM63705.1 - 2.3e-16 59.4 0.7 6e-16 58.1 0.7 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Octopine_DH PF02317.17 KUM63706.1 - 7.5e-45 152.7 0.0 1.2e-44 152.1 0.0 1.3 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.23 KUM63706.1 - 2.1e-07 31.1 0.0 4.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_8 PF13450.6 KUM63706.1 - 0.00035 20.7 0.0 0.00078 19.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM63706.1 - 0.0021 17.3 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KUM63706.1 - 0.0048 16.0 0.8 0.0067 15.6 0.2 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A ApbA PF02558.16 KUM63706.1 - 0.0088 15.7 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KUM63706.1 - 0.017 15.7 0.0 0.045 14.3 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.19 KUM63706.1 - 0.022 14.0 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 KUM63706.1 - 0.023 13.8 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KUM63706.1 - 0.028 13.1 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KUM63706.1 - 0.05 14.2 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM63706.1 - 0.054 13.1 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KUM63706.1 - 0.16 11.2 0.2 0.33 10.2 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KUM63707.1 - 3.6e-55 187.3 10.1 3.6e-55 187.3 10.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM63707.1 - 1.5e-13 50.5 8.9 1.5e-13 50.5 8.9 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_5 PF05631.14 KUM63707.1 - 3e-05 23.1 4.6 0.00084 18.4 1.7 2.2 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 KUM63707.1 - 4.4e-05 22.5 3.8 0.043 12.7 4.9 2.9 2 1 1 3 3 3 3 MFS_1 like family TRI12 PF06609.13 KUM63707.1 - 0.00016 20.2 2.5 0.00029 19.4 2.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KUM63709.1 - 1.5e-06 27.4 8.9 1.7e-06 27.2 8.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM63709.1 - 0.00012 21.1 6.8 0.00018 20.5 6.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter PSI_PSAK PF01241.18 KUM63709.1 - 0.015 15.3 1.3 0.12 12.4 0.1 2.3 2 0 0 2 2 2 0 Photosystem I psaG / psaK DIM PF08194.12 KUM63709.1 - 8.2 6.7 7.4 2.3 8.5 0.3 2.9 3 0 0 3 3 3 0 DIM protein MFS_1 PF07690.16 KUM63710.1 - 8e-06 25.0 24.0 1.8e-05 23.9 23.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Pox_A14 PF05767.12 KUM63710.1 - 0.39 10.9 2.3 40 4.4 0.2 3.4 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 PALP PF00291.25 KUM63711.1 - 3.8e-62 210.3 0.7 3.8e-62 210.3 0.7 2.0 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.28 KUM63711.1 - 1.1e-28 100.4 0.1 2.6e-28 99.1 0.1 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KUM63711.1 - 9.3e-19 67.4 0.0 2.8e-18 65.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KUM63711.1 - 0.00083 19.1 0.1 0.002 17.8 0.1 1.7 1 0 0 1 1 1 1 Peptidase family M28 LpxI_N PF17930.1 KUM63711.1 - 0.023 14.6 0.0 0.083 12.8 0.0 1.9 1 0 0 1 1 1 0 LpxI N-terminal domain GET2 PF08690.10 KUM63712.1 - 1.7e-13 51.0 4.8 1.2e-12 48.2 4.8 1.9 1 1 0 1 1 1 1 GET complex subunit GET2 PepSY_TM PF03929.16 KUM63712.1 - 0.041 13.6 0.0 0.041 13.6 0.0 2.2 2 1 0 2 2 2 0 PepSY-associated TM region adh_short_C2 PF13561.6 KUM63713.1 - 7e-56 189.4 0.0 8.6e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM63713.1 - 5.3e-46 156.6 0.1 6.2e-46 156.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM63713.1 - 3.5e-10 40.1 0.3 4.9e-10 39.6 0.3 1.1 1 0 0 1 1 1 1 KR domain ApoA-II PF04711.13 KUM63713.1 - 0.013 15.7 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) Aa_trans PF01490.18 KUM63717.1 - 1.4e-38 132.7 35.6 1.7e-38 132.4 35.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Phage_holin_1 PF04531.13 KUM63717.1 - 0.038 14.5 1.1 0.038 14.5 1.1 3.5 4 1 1 5 5 5 0 Bacteriophage holin Caveolin PF01146.17 KUM63717.1 - 0.49 10.3 0.1 0.49 10.3 0.1 3.4 2 1 0 3 3 3 0 Caveolin DUF3481 PF11980.8 KUM63717.1 - 3.5 7.4 7.4 0.77 9.5 0.6 2.8 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein Sugar_tr PF00083.24 KUM63718.1 - 2.5e-118 395.8 20.4 3.8e-118 395.2 20.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM63718.1 - 6.2e-29 101.0 51.2 1.6e-27 96.4 26.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM63718.1 - 3.4e-05 22.5 3.0 3.4e-05 22.5 3.0 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 KUM63719.1 - 2.9e-59 201.0 0.0 3.8e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 KUM63720.1 - 2.3e-51 175.0 44.3 2.9e-51 174.7 44.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM63720.1 - 3.7e-23 81.9 37.4 5.3e-23 81.4 37.4 1.1 1 0 0 1 1 1 1 Amino acid permease YlaH PF14036.6 KUM63720.1 - 3.5 8.0 11.4 0.1 12.9 2.8 2.9 3 0 0 3 3 3 0 YlaH-like protein NmrA PF05368.13 KUM63721.1 - 5.8e-20 71.9 0.0 7.6e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KUM63721.1 - 0.0017 18.6 0.0 0.0057 16.9 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain MG2 PF01835.19 KUM63721.1 - 0.14 12.7 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 MG2 domain Peptidase_M20 PF01546.28 KUM63722.1 - 4.6e-23 82.0 0.1 1e-22 80.9 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KUM63722.1 - 2.6e-16 59.5 0.0 4.5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KUM63722.1 - 0.00067 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Aminotran_1_2 PF00155.21 KUM63723.1 - 7.9e-72 242.4 0.0 9e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II APH PF01636.23 KUM63724.1 - 0.037 14.0 0.2 0.32 10.9 0.4 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 KUM63725.1 - 2.2e-105 341.6 40.9 9.3e-10 39.0 0.1 12.5 13 0 0 13 13 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM63725.1 - 9.4e-35 118.8 3.1 0.00039 20.7 0.0 10.9 2 2 9 11 11 11 9 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KUM63725.1 - 2.6e-22 79.2 10.8 0.28 10.1 0.0 11.0 2 2 9 11 11 11 9 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KUM63725.1 - 2e-18 65.8 13.6 0.2 11.6 0.0 10.5 10 0 0 10 10 10 5 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KUM63725.1 - 1.2e-10 40.7 13.5 0.12 11.0 0.7 8.1 2 1 6 8 8 8 4 Nucleoporin Nup120/160 NACHT PF05729.12 KUM63725.1 - 1.7e-10 41.1 0.1 3.3e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 KUM63725.1 - 2e-10 40.3 0.0 4.2e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily Proteasome_A_N PF10584.9 KUM63725.1 - 1.1e-05 25.0 2.1 52 3.6 0.0 7.4 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature HARP PF07443.13 KUM63725.1 - 0.017 14.8 0.0 42 3.9 0.0 4.9 5 0 0 5 5 5 0 HepA-related protein (HARP) DPPIV_N PF00930.21 KUM63725.1 - 0.018 13.8 0.9 85 1.7 0.0 5.8 7 1 0 8 8 8 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_M3 PF01432.20 KUM63725.1 - 0.019 14.2 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M3 Cytochrom_D1 PF02239.16 KUM63725.1 - 0.084 11.4 1.6 5.5 5.4 0.1 3.3 2 2 0 2 2 2 0 Cytochrome D1 heme domain SIR2 PF02146.17 KUM63727.1 - 2.6e-31 108.9 0.0 4.3e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Sir2 family adh_short PF00106.25 KUM63728.1 - 1e-22 80.6 0.1 2.6e-18 66.2 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM63728.1 - 1.3e-13 51.1 0.0 1e-09 38.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM63728.1 - 2.6e-05 24.2 0.1 4.1e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 KR domain ABC_tran PF00005.27 KUM63729.1 - 3.7e-44 150.6 0.0 4.2e-27 95.3 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 KUM63729.1 - 5.4e-18 65.6 20.4 1.3e-12 48.0 7.3 3.2 2 1 1 3 3 3 2 ABC transporter transmembrane region AAA_22 PF13401.6 KUM63729.1 - 1.5e-08 35.0 0.0 0.0025 18.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.19 KUM63729.1 - 1.6e-08 34.2 0.2 0.018 14.5 0.0 3.5 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KUM63729.1 - 2.5e-08 34.1 0.6 0.001 19.0 0.0 3.6 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KUM63729.1 - 3.1e-08 33.7 0.1 0.0031 17.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KUM63729.1 - 4.4e-08 33.9 0.0 0.00057 20.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KUM63729.1 - 1.9e-07 30.7 2.8 0.0045 16.7 0.0 3.1 4 0 0 4 4 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KUM63729.1 - 7e-07 29.8 0.0 0.056 13.8 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_7 PF12775.7 KUM63729.1 - 8.7e-06 25.4 0.1 0.17 11.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region T2SSE PF00437.20 KUM63729.1 - 2.2e-05 23.7 0.0 0.0053 15.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein cobW PF02492.19 KUM63729.1 - 2.3e-05 24.1 0.5 0.11 12.1 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 KUM63729.1 - 3.1e-05 23.9 0.1 0.11 12.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KUM63729.1 - 4.2e-05 24.0 0.0 0.091 13.2 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KUM63729.1 - 4.5e-05 23.6 0.1 0.35 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Roc PF08477.13 KUM63729.1 - 0.00013 22.1 0.1 2.1 8.6 0.0 3.4 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KUM63729.1 - 0.00014 21.5 0.0 0.2 11.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain ABC_ATPase PF09818.9 KUM63729.1 - 0.00019 20.4 0.0 0.47 9.2 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class ATPase_2 PF01637.18 KUM63729.1 - 0.00031 20.7 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KUM63729.1 - 0.00055 20.0 0.0 0.46 10.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 KUM63729.1 - 0.0006 19.6 0.1 0.21 11.3 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 KUM63729.1 - 0.00061 19.8 0.1 1.2 9.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KUM63729.1 - 0.00065 20.1 0.1 2.1 8.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Septin PF00735.18 KUM63729.1 - 0.00067 19.0 0.0 0.35 10.1 0.0 2.3 2 0 0 2 2 2 1 Septin NB-ARC PF00931.22 KUM63729.1 - 0.00074 18.8 0.1 0.21 10.7 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.15 KUM63729.1 - 0.0013 18.7 0.2 0.22 11.4 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain ATP_bind_1 PF03029.17 KUM63729.1 - 0.0021 17.9 0.7 0.87 9.3 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 KUM63729.1 - 0.0023 18.3 0.1 1.4 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KUM63729.1 - 0.0023 18.0 0.0 3.1 7.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_11 PF13086.6 KUM63729.1 - 0.0028 17.5 0.1 2.4 7.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KUM63729.1 - 0.0029 17.5 0.2 1.1 9.1 0.0 2.6 2 0 0 2 2 2 1 NTPase IstB_IS21 PF01695.17 KUM63729.1 - 0.0032 17.2 0.3 0.73 9.5 0.0 2.7 3 0 0 3 3 2 1 IstB-like ATP binding protein MobB PF03205.14 KUM63729.1 - 0.0036 17.2 0.1 0.64 9.9 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 KUM63729.1 - 0.0042 17.6 0.0 1.2 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KUM63729.1 - 0.0043 16.8 0.0 0.34 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 KUM63729.1 - 0.0087 15.8 0.3 0.067 12.9 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family TsaE PF02367.17 KUM63729.1 - 0.01 15.9 0.0 3.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Adeno_IVa2 PF02456.15 KUM63729.1 - 0.011 14.6 0.1 0.22 10.3 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein NACHT PF05729.12 KUM63729.1 - 0.012 15.6 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 KUM63729.1 - 0.012 15.7 0.6 1.8 8.6 0.1 2.5 2 0 0 2 2 2 0 Dynamin family DUF815 PF05673.13 KUM63729.1 - 0.018 14.2 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 KUM63729.1 - 0.022 14.5 0.1 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_35 PF14516.6 KUM63729.1 - 0.025 13.4 0.1 0.092 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain RNA12 PF10443.9 KUM63729.1 - 0.032 13.0 0.2 0.41 9.3 0.0 2.1 2 0 0 2 2 2 0 RNA12 protein Zeta_toxin PF06414.12 KUM63729.1 - 0.032 13.5 0.0 3.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KUM63729.1 - 0.033 13.5 0.4 0.3 10.4 0.1 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 KUM63729.1 - 0.04 13.6 0.1 8 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_PrkA PF08298.11 KUM63729.1 - 0.042 12.8 0.0 0.54 9.1 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_28 PF13521.6 KUM63729.1 - 0.16 12.2 1.1 15 5.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KUM63729.1 - 0.21 11.9 0.1 2.3 8.5 0.1 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MFS_1 PF07690.16 KUM63731.1 - 1.1e-34 119.9 43.3 1.5e-33 116.2 43.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM63731.1 - 7e-13 47.9 21.1 1.8e-12 46.5 21.1 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM63731.1 - 1.9e-07 30.3 16.0 3.8e-07 29.3 10.2 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter DUF2781 PF10914.8 KUM63731.1 - 0.017 15.5 2.4 0.038 14.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2781) RseC_MucC PF04246.12 KUM63731.1 - 1.9 8.4 7.1 17 5.4 0.2 3.6 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Peptidase_M19 PF01244.21 KUM63733.1 - 1.2e-101 340.1 0.2 1.4e-101 339.8 0.2 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) GDPD_2 PF13653.6 KUM63733.1 - 0.028 14.9 2.6 0.16 12.4 0.1 3.2 2 1 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family HHH_8 PF14716.6 KUM63733.1 - 0.17 12.3 0.2 22 5.5 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain Hydantoinase_B PF02538.14 KUM63734.1 - 4.1e-209 695.3 0.1 5.6e-209 694.8 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KUM63734.1 - 8.5e-95 317.3 0.1 1.7e-94 316.4 0.1 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KUM63734.1 - 5.7e-56 189.0 0.0 1.1e-54 184.9 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Phage_X PF05155.15 KUM63734.1 - 0.065 13.7 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Phage X family 2-Hacid_dh_C PF02826.19 KUM63735.1 - 2.2e-37 128.1 0.0 2.9e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KUM63735.1 - 1.1e-14 54.3 0.0 1.4e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KUM63735.1 - 0.004 17.3 0.0 0.0091 16.2 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KUM63735.1 - 0.058 14.0 0.1 0.11 13.0 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Helicase_C PF00271.31 KUM63736.1 - 6.9e-06 26.4 0.1 1.3e-05 25.5 0.0 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1125 PF06563.11 KUM63736.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1125) GDE_N PF12439.8 KUM63736.1 - 0.14 11.6 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal Helo_like_N PF17111.5 KUM63737.1 - 3.3e-07 29.9 0.2 4.6e-07 29.4 0.2 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KUM63737.1 - 1.8e-06 28.1 0.1 2.7e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases MFS_1 PF07690.16 KUM63738.1 - 3e-44 151.4 63.9 7.2e-44 150.2 58.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM63738.1 - 1.7e-14 53.2 31.8 2.8e-14 52.5 31.8 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM63738.1 - 8e-12 44.8 12.5 8e-12 44.8 12.5 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KUM63738.1 - 1.8 6.7 22.0 1.4 7.1 8.0 2.8 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family NAD_binding_8 PF13450.6 KUM63739.1 - 9.8e-14 51.3 0.3 2.6e-13 50.0 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KUM63739.1 - 3.6e-06 26.6 4.9 1.1e-05 24.9 3.6 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM63739.1 - 1.5e-05 24.4 0.1 7.2e-05 22.1 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM63739.1 - 3.9e-05 22.9 2.5 6.6e-05 22.2 2.5 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KUM63739.1 - 6.4e-05 21.8 1.1 0.00021 20.1 0.7 1.8 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KUM63739.1 - 0.00016 21.4 2.7 0.00031 20.4 2.7 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KUM63739.1 - 0.00022 20.7 0.2 0.0041 16.5 0.2 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KUM63739.1 - 0.0006 20.3 0.2 0.0032 18.0 0.2 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KUM63739.1 - 0.00065 19.0 0.2 0.0013 18.0 0.2 1.4 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 KUM63739.1 - 0.00098 18.3 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KUM63739.1 - 0.0014 17.8 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KUM63739.1 - 0.004 16.5 0.0 0.0071 15.6 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KUM63739.1 - 0.054 12.7 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM63739.1 - 0.073 13.1 0.9 1.4 8.9 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 KUM63739.1 - 0.3 10.1 1.1 0.45 9.5 1.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pkinase PF00069.25 KUM63740.1 - 2.1e-75 253.5 0.0 2.5e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM63740.1 - 4.6e-36 124.4 0.0 6.2e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KUM63740.1 - 7.9e-05 21.8 0.0 0.0011 18.0 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KUM63740.1 - 0.0055 16.1 1.4 0.054 12.8 0.1 2.8 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.14 KUM63740.1 - 0.011 15.1 0.1 0.025 14.0 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KUM63740.1 - 0.046 13.6 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KUM63740.1 - 0.05 12.7 0.0 0.18 10.9 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 Dicty_CAR PF05462.11 KUM63741.1 - 6.6e-07 28.8 15.0 1.7e-06 27.4 7.5 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3 PF11710.8 KUM63741.1 - 0.0026 17.6 7.2 0.0026 17.6 7.2 1.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Nnf1 PF03980.14 KUM63742.1 - 2.5e-33 114.7 7.2 4.1e-33 114.1 7.2 1.3 1 0 0 1 1 1 1 Nnf1 BAG6 PF12057.8 KUM63742.1 - 0.002 17.8 0.5 0.0034 17.1 0.5 1.4 1 0 0 1 1 1 1 BCL2-associated athanogene 6 Apolipoprotein PF01442.18 KUM63742.1 - 0.14 12.0 12.9 0.7 9.7 10.4 2.1 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain TPR_11 PF13414.6 KUM63743.1 - 0.021 14.5 5.6 0.37 10.5 0.0 4.3 6 0 0 6 6 6 0 TPR repeat TPR_17 PF13431.6 KUM63743.1 - 0.026 14.9 0.8 6.7 7.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 KUM63743.1 - 5.5 7.1 7.3 7.2 6.8 0.5 4.0 4 0 0 4 4 4 0 Exonuclease VII small subunit X PF00739.19 KUM63744.1 - 0.13 12.4 6.8 0.22 11.7 6.8 1.4 1 0 0 1 1 1 0 Trans-activation protein X Macoilin PF09726.9 KUM63744.1 - 0.22 10.1 3.0 0.22 10.0 3.0 1.0 1 0 0 1 1 1 0 Macoilin family DUF508 PF04370.12 KUM63744.1 - 3.9 7.2 10.2 6.5 6.5 10.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF508) RAP1 PF07218.11 KUM63744.1 - 8.4 4.5 7.9 8.7 4.5 7.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NTF2 PF02136.20 KUM63745.1 - 1.2e-26 93.7 0.2 1.9e-26 93.0 0.2 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KUM63745.1 - 1.4e-07 31.2 0.0 2.9e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNF2_N PF00176.23 KUM63746.1 - 4.2e-12 45.4 0.1 6e-12 45.0 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain PNP_UDP_1 PF01048.20 KUM63747.1 - 6.7e-13 48.4 0.2 2.7e-12 46.5 0.2 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily zf-H2C2_2 PF13465.6 KUM63747.1 - 8.1e-08 32.4 1.0 8.1e-08 32.4 1.0 4.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 KUM63747.1 - 0.0037 17.6 2.4 0.0037 17.6 2.4 4.6 4 0 0 4 4 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM63747.1 - 0.0082 16.9 1.6 0.0082 16.9 1.6 5.3 4 0 0 4 4 4 2 C2H2-type zinc finger Mu-like_Com PF10122.9 KUM63747.1 - 0.034 13.6 0.0 0.097 12.1 0.0 1.7 1 0 0 1 1 1 0 Mu-like prophage protein Com SPX PF03105.19 KUM63747.1 - 0.048 13.6 1.2 0.056 13.4 0.0 1.6 2 0 0 2 2 2 0 SPX domain zf-C2H2_3rep PF18868.1 KUM63747.1 - 0.08 13.6 7.1 0.26 12.0 7.1 1.9 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KUM63747.1 - 0.25 11.8 4.0 8.3 7.0 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KUM63747.1 - 0.45 10.9 7.3 1.8 9.0 1.3 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Phage_GPL PF05926.11 KUM63747.1 - 0.46 10.5 3.3 2 8.4 0.6 2.7 2 0 0 2 2 2 0 Phage head completion protein (GPL) zf-C2H2_6 PF13912.6 KUM63747.1 - 7.1 6.8 7.6 5.5 7.1 2.2 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger MFS_1 PF07690.16 KUM63749.1 - 6.2e-42 143.8 26.7 6.2e-42 143.8 26.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KUM63749.1 - 0.0046 16.7 2.5 0.0046 16.7 2.5 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 SR-25 PF10500.9 KUM63750.1 - 5.1e-05 23.0 10.3 5.2e-05 23.0 10.3 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Nha1_C PF08619.10 KUM63750.1 - 0.004 16.4 5.7 0.0044 16.3 5.7 1.0 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus RNA_pol_3_Rpc31 PF11705.8 KUM63750.1 - 0.0092 16.3 2.8 0.0098 16.2 2.8 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Peptidase_S49_N PF08496.10 KUM63750.1 - 0.023 14.8 4.5 0.023 14.8 4.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AP3D1 PF06375.11 KUM63750.1 - 0.05 13.8 10.4 0.051 13.8 10.4 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Connexin PF00029.19 KUM63750.1 - 0.18 11.5 0.7 0.21 11.3 0.7 1.1 1 0 0 1 1 1 0 Connexin Med19 PF10278.9 KUM63750.1 - 0.23 11.4 14.0 0.26 11.2 14.0 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 OAD_gamma PF04277.13 KUM63750.1 - 0.43 11.2 4.6 0.51 11.0 4.6 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3464 PF11947.8 KUM63750.1 - 1.3 8.7 5.0 1.6 8.5 5.0 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 V_ATPase_I PF01496.19 KUM63751.1 - 0.0017 16.4 0.0 0.002 16.2 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Spo7 PF03907.13 KUM63751.1 - 0.027 14.0 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 Spo7-like protein Imm-NTF2 PF15655.6 KUM63751.1 - 0.13 12.6 0.1 0.22 11.8 0.1 1.3 1 0 0 1 1 1 0 NTF2 fold immunity protein Cation_efflux PF01545.21 KUM63752.1 - 1.8e-61 207.3 4.1 2.2e-61 207.1 4.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KUM63752.1 - 0.00017 21.6 0.5 0.00017 21.6 0.5 2.0 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter DUF749 PF05370.11 KUM63752.1 - 0.17 12.0 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF749) FGGY_C PF02782.16 KUM63753.1 - 3.8e-32 111.6 0.0 6.2e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KUM63753.1 - 5e-23 81.9 0.0 1.9e-14 53.8 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.12 KUM63754.1 - 1.9e-40 138.3 1.6 8.3e-40 136.3 0.1 3.0 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.22 KUM63754.1 - 0.0076 16.4 0.2 10 6.7 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat DUF3311 PF11755.8 KUM63755.1 - 0.29 11.1 4.2 4.3 7.4 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3311) ADH_N PF08240.12 KUM63756.1 - 6.3e-21 74.3 0.4 1e-20 73.6 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM63756.1 - 1.1e-17 64.3 0.0 2e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM63756.1 - 2.1e-06 28.8 0.0 3.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KUM63756.1 - 0.02 14.3 0.8 0.034 13.5 0.8 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.10 KUM63756.1 - 0.15 12.0 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 KR domain Nucleopor_Nup85 PF07575.13 KUM63757.1 - 5.2e-25 88.1 0.0 1.4e-18 66.8 0.0 2.7 2 1 0 2 2 2 2 Nup85 Nucleoporin TGF_beta_GS PF08515.12 KUM63757.1 - 0.11 12.0 0.5 0.35 10.4 0.5 1.9 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Glyco_hydro_76 PF03663.14 KUM63760.1 - 7.4e-105 351.5 19.7 8.6e-105 351.2 19.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KUM63760.1 - 0.0017 17.5 0.2 0.0017 17.5 0.2 2.3 2 1 0 2 2 2 1 Glycosyl Hydrolase Family 88 ADIP PF11559.8 KUM63762.1 - 1.4e-41 142.1 8.7 1.4e-41 142.1 8.7 2.7 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 KUM63762.1 - 0.0012 18.4 9.9 0.0012 18.4 9.9 2.6 3 0 0 3 3 3 1 Golgin subfamily A member 5 Spc7 PF08317.11 KUM63762.1 - 0.0019 17.1 5.2 0.0019 17.1 5.2 2.4 2 0 0 2 2 2 1 Spc7 kinetochore protein KASH_CCD PF14662.6 KUM63762.1 - 0.014 15.2 10.9 0.014 15.2 10.9 3.0 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH TTRAP PF14203.6 KUM63762.1 - 0.052 13.5 0.9 0.2 11.6 0.1 2.4 2 0 0 2 2 1 0 Putative tranposon-transfer assisting protein RepA_C PF04796.12 KUM63762.1 - 0.12 12.4 0.5 0.29 11.2 0.5 1.6 1 0 0 1 1 1 0 Plasmid encoded RepA protein DUF641 PF04859.12 KUM63762.1 - 0.28 11.5 13.6 0.54 10.6 5.2 3.5 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.11 KUM63762.1 - 0.51 10.8 5.0 1.3 9.5 0.6 3.5 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) KxDL PF10241.9 KUM63762.1 - 1.3 9.4 9.9 0.6 10.4 6.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein Prominin PF05478.11 KUM63762.1 - 1.5 6.6 8.0 2.2 6.1 8.0 1.1 1 0 0 1 1 1 0 Prominin DUF724 PF05266.14 KUM63762.1 - 2.3 8.0 15.9 0.13 12.0 7.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Fez1 PF06818.15 KUM63762.1 - 2.3 8.6 27.8 0.032 14.7 14.1 3.1 2 1 1 3 3 3 0 Fez1 DUF1664 PF07889.12 KUM63762.1 - 5.2 7.1 8.7 1.4 9.0 3.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF465 PF04325.13 KUM63762.1 - 5.2 7.2 6.3 2.6 8.1 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF465) Zn_clus PF00172.18 KUM63763.1 - 2e-08 34.2 10.1 3.4e-08 33.5 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM63763.1 - 5.3e-07 28.8 0.0 7.5e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aa_trans PF01490.18 KUM63764.1 - 5.6e-39 134.0 35.8 6.8e-39 133.7 35.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KUM63764.1 - 6.8e-05 22.1 15.7 6.8e-05 22.1 15.7 2.4 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2649 PF10854.8 KUM63764.1 - 0.53 10.6 5.7 0.88 9.9 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) GWT1 PF06423.12 KUM63764.1 - 5.2 7.2 13.1 0.24 11.5 2.4 3.0 2 2 0 2 2 2 0 GWT1 DUF872 PF05915.12 KUM63764.1 - 7 6.9 7.4 5.2 7.3 1.2 3.1 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Rad51 PF08423.11 KUM63765.1 - 4.9e-111 370.0 0.0 6.2e-111 369.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KUM63765.1 - 1.3e-11 44.5 0.0 1.7e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KUM63765.1 - 1.1e-08 35.5 1.6 3.5e-08 33.9 0.4 2.4 3 0 0 3 3 3 1 Helix-hairpin-helix domain ATPase PF06745.13 KUM63765.1 - 3.7e-08 33.0 0.0 8.1e-08 31.9 0.0 1.7 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KUM63765.1 - 0.00017 21.3 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KUM63765.1 - 0.056 12.8 0.1 0.72 9.1 0.1 2.1 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain zf-CCHC PF00098.23 KUM63766.1 - 2.1e-45 150.9 53.8 2.5e-07 30.4 0.9 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KUM63766.1 - 1.7e-09 37.3 39.2 0.044 13.5 0.4 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 KUM63766.1 - 8.9e-09 35.2 36.7 0.014 15.3 0.0 7.0 5 2 1 6 6 6 4 Zinc knuckle zf-CCHC_5 PF14787.6 KUM63766.1 - 0.0011 18.6 41.3 0.021 14.5 0.8 7.0 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 KUM63766.1 - 9.7 6.1 48.1 0.74 9.7 1.4 6.9 6 1 1 7 7 7 0 Zinc knuckle TFB6 PF17110.5 KUM63767.1 - 3.7e-34 117.9 0.0 5.7e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH RRM_Rrp7 PF17799.1 KUM63768.1 - 6.4e-31 107.3 0.0 1e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 KUM63768.1 - 2.7e-26 92.0 9.3 2.7e-26 92.0 9.3 2.1 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_1 PF00076.22 KUM63768.1 - 0.029 14.2 0.0 2.1 8.2 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dak1_2 PF13684.6 KUM63768.1 - 0.12 11.4 1.8 1.7 7.7 0.0 2.3 2 1 0 2 2 2 0 Dihydroxyacetone kinase family DUF5093 PF17011.5 KUM63768.1 - 0.22 11.8 6.6 1.2 9.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5093) UPF0172 PF03665.13 KUM63768.1 - 0.41 10.7 3.3 0.19 11.8 0.6 1.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0172) Pro_isomerase PF00160.21 KUM63769.1 - 1.3e-37 129.5 0.0 1.9e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KUM63769.1 - 1e-14 54.1 0.0 2e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 KUM63770.1 - 1e-08 35.1 6.5 1.9e-08 34.3 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UDPGP PF01704.18 KUM63771.1 - 3.9e-58 197.1 0.0 4.7e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase LysM PF01476.20 KUM63772.1 - 1.9e-08 34.2 0.0 0.25 11.4 0.0 4.2 4 0 0 4 4 4 3 LysM domain DUF4178 PF13785.6 KUM63772.1 - 0.087 12.9 0.1 0.7 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4178) Glyco_hydro_18 PF00704.28 KUM63773.1 - 6e-67 226.6 4.1 9.3e-67 226.0 4.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ank_2 PF12796.7 KUM63774.1 - 6.2e-25 87.6 4.5 3.7e-11 43.5 0.2 4.9 1 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KUM63774.1 - 8.6e-25 84.1 0.7 0.0051 17.2 0.0 8.6 9 0 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.6 KUM63774.1 - 1.3e-23 83.0 0.1 8.7e-10 39.0 0.0 7.5 7 1 1 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 KUM63774.1 - 2.1e-16 59.6 0.5 0.038 14.4 0.0 7.3 7 1 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KUM63774.1 - 1.3e-13 50.9 0.1 1.6e-07 31.4 0.1 6.2 5 1 2 7 7 7 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 KUM63774.1 - 0.14 12.1 0.0 6 6.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) Sugar_tr PF00083.24 KUM63776.1 - 2.5e-10 39.8 11.7 2.9e-10 39.6 11.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Glyco_transf_34 PF05637.12 KUM63778.1 - 5.8e-09 36.0 0.1 7.6e-05 22.5 0.0 2.3 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF1664 PF07889.12 KUM63778.1 - 0.088 12.9 0.2 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF273 PF03314.14 KUM63778.1 - 0.19 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 KUM63779.1 - 3.5e-05 23.9 0.0 5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 KUM63779.1 - 0.0033 17.2 0.1 0.019 14.7 0.1 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family IDO PF01231.18 KUM63780.1 - 4.2e-33 114.8 0.0 6.2e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase TPR_2 PF07719.17 KUM63781.1 - 1.1e-11 43.9 7.1 0.007 16.4 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KUM63781.1 - 4.8e-07 30.2 3.5 0.014 15.9 0.4 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat F-box PF00646.33 KUM63781.1 - 1e-06 28.5 0.1 3.7e-06 26.7 0.1 2.0 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 KUM63781.1 - 2.8e-06 26.9 7.6 0.085 12.7 0.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KUM63781.1 - 6.7e-05 22.6 1.8 0.14 12.2 0.1 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KUM63781.1 - 8.2e-05 23.1 3.8 0.15 12.9 0.5 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KUM63781.1 - 9.2e-05 22.7 5.1 0.066 13.5 1.5 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KUM63781.1 - 0.00023 21.7 5.3 0.019 15.6 2.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KUM63781.1 - 0.00027 21.0 2.8 0.0049 17.0 1.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat F-box-like PF12937.7 KUM63781.1 - 0.0014 18.5 0.1 0.0029 17.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like TPR_17 PF13431.6 KUM63781.1 - 0.011 16.1 4.0 2.1 8.9 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat LRR_4 PF12799.7 KUM63781.1 - 0.014 15.8 9.7 1.7 9.1 0.0 6.4 6 2 2 8 8 7 0 Leucine Rich repeats (2 copies) ChAPs PF09295.10 KUM63781.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 KUM63781.1 - 0.17 12.3 2.5 11 6.5 0.4 2.4 1 1 1 2 2 2 0 Bacterial transcriptional activator domain ANAPC3 PF12895.7 KUM63781.1 - 0.24 11.6 2.2 1.9 8.8 0.1 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KUM63781.1 - 0.29 10.8 4.7 0.69 9.6 4.7 1.5 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 KUM63781.1 - 0.4 10.4 2.9 3.7 7.3 0.1 2.8 1 1 2 3 3 3 0 TPR repeat TPR_10 PF13374.6 KUM63781.1 - 0.59 10.1 6.0 3.4 7.7 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KUM63781.1 - 0.86 10.0 6.3 33 5.0 0.1 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KUM63781.1 - 3.5 7.8 5.4 4.6 7.4 0.2 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 KUM63781.1 - 5 8.0 8.5 16 6.4 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Arrestin_N PF00339.29 KUM63782.1 - 1.9e-12 47.4 0.7 1.9e-10 41.0 0.2 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain V-ATPase_G PF03179.15 KUM63784.1 - 7.4e-28 97.2 15.2 9.1e-28 96.9 15.2 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit RR_TM4-6 PF06459.12 KUM63784.1 - 0.24 11.2 8.4 0.3 10.9 8.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ATP-synt_B PF00430.18 KUM63784.1 - 6.9 6.8 22.5 3.4 7.8 13.2 2.4 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) PET117 PF15786.5 KUM63785.1 - 6.7e-22 77.5 0.5 8e-22 77.3 0.5 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Cep57_CLD PF14073.6 KUM63785.1 - 0.0082 16.2 0.5 0.01 15.9 0.5 1.1 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 RPA_interact_M PF14767.6 KUM63785.1 - 0.03 14.9 0.1 0.036 14.6 0.1 1.1 1 0 0 1 1 1 0 Replication protein A interacting middle Fib_alpha PF08702.10 KUM63789.1 - 0.00081 19.6 16.2 0.0012 19.0 2.8 3.2 2 1 0 2 2 2 1 Fibrinogen alpha/beta chain family DivIVA PF05103.13 KUM63789.1 - 0.0083 16.2 34.0 0.38 10.8 13.1 4.0 2 1 2 4 4 4 3 DivIVA protein DUF948 PF06103.11 KUM63789.1 - 0.023 15.0 8.1 0.43 10.9 1.2 3.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Mod_r PF07200.13 KUM63789.1 - 0.52 10.4 30.7 0.07 13.2 18.5 3.4 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Fez1 PF06818.15 KUM63789.1 - 1.9 8.9 35.3 2.3 8.6 25.7 2.8 2 1 0 2 2 2 0 Fez1 Phage_GP20 PF06810.11 KUM63789.1 - 2.3 8.0 16.4 4.4 7.1 6.7 3.1 2 1 1 3 3 3 0 Phage minor structural protein GP20 YabA PF06156.13 KUM63789.1 - 3.5 8.3 23.4 16 6.2 0.5 3.7 1 1 2 3 3 3 0 Initiation control protein YabA Laminin_II PF06009.12 KUM63789.1 - 8.4 6.4 21.1 7.6 6.6 4.5 3.3 2 1 1 3 3 3 0 Laminin Domain II Methyltransf_16 PF10294.9 KUM63790.1 - 3.9e-16 59.3 0.0 2e-15 56.9 0.0 1.9 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KUM63790.1 - 0.0012 19.5 0.0 0.0027 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KUM63790.1 - 0.0033 17.0 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KUM63790.1 - 0.0066 16.2 0.0 0.0099 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KUM63790.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KUM63790.1 - 0.019 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KUM63790.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KUM63790.1 - 0.19 11.5 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein CLTH PF10607.9 KUM63791.1 - 8.5e-32 110.1 0.0 1.4e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KUM63791.1 - 3.1e-25 88.6 0.2 5.6e-25 87.8 0.2 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KUM63791.1 - 0.00025 20.9 0.1 0.00093 19.1 0.0 2.1 2 0 0 2 2 2 1 LisH DnaJ PF00226.31 KUM63792.1 - 1.1e-15 57.5 0.1 1.8e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain INO80_Ies4 PF08193.11 KUM63793.1 - 3.9e-65 220.2 17.6 4.8e-65 219.9 17.6 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 Pyr_redox_2 PF07992.14 KUM63794.1 - 8.7e-47 159.8 0.0 1.2e-46 159.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KUM63794.1 - 7e-16 57.9 0.0 1.9e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KUM63794.1 - 6.6e-14 52.2 0.2 1.7e-11 44.5 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 KUM63794.1 - 0.00015 21.6 0.0 0.00062 19.7 0.0 2.1 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain DUF1188 PF06690.11 KUM63794.1 - 0.00026 20.6 0.0 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) Reductase_C PF14759.6 KUM63794.1 - 0.00031 21.2 0.0 0.001 19.6 0.0 1.9 2 0 0 2 2 2 1 Reductase C-terminal NAD_binding_9 PF13454.6 KUM63794.1 - 0.00071 19.6 0.1 3.7 7.5 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding TrkA_N PF02254.18 KUM63794.1 - 0.023 14.9 0.3 5.1 7.4 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain RPA43_OB PF17875.1 KUM63795.1 - 9.9e-40 136.0 0.0 9.9e-40 136.0 0.0 3.0 3 0 0 3 3 3 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KUM63795.1 - 3.9e-07 30.3 0.0 1.1e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DDHD PF02862.17 KUM63795.1 - 0.08 13.1 7.0 0.78 9.9 3.1 2.4 2 0 0 2 2 2 0 DDHD domain RTA1 PF04479.13 KUM63796.1 - 3.6e-70 235.8 9.0 3.6e-70 235.8 9.0 1.8 1 1 1 2 2 2 1 RTA1 like protein Ribosomal_S24e PF01282.19 KUM63797.1 - 3.3e-35 119.9 0.2 5.5e-35 119.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.6 KUM63797.1 - 0.0091 15.9 1.8 0.012 15.5 1.3 1.5 1 1 0 1 1 1 1 RRXRR protein FAD_binding_4 PF01565.23 KUM63797.1 - 0.097 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain YmzC PF14157.6 KUM63800.1 - 0.21 11.7 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 YmzC-like protein BAR PF03114.18 KUM63803.1 - 8.5e-65 218.7 9.5 1.1e-64 218.3 9.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KUM63803.1 - 2.2e-13 49.6 0.0 4.3e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KUM63803.1 - 2.6e-11 43.2 0.1 4.3e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KUM63803.1 - 2.4e-08 33.5 0.1 7.1e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.10 KUM63803.1 - 0.026 14.1 4.4 1 8.8 2.0 2.2 2 0 0 2 2 2 0 Vps5 C terminal like CT_C_D PF02682.16 KUM63803.1 - 0.064 13.0 0.5 0.12 12.1 0.5 1.4 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D Zn_dep_PLPC PF00882.18 KUM63803.1 - 0.097 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Zinc dependent phospholipase C TMPIT PF07851.13 KUM63803.1 - 0.11 11.7 6.1 0.3 10.3 0.1 2.2 1 1 1 2 2 2 0 TMPIT-like protein YlqD PF11068.8 KUM63803.1 - 0.6 10.5 0.0 0.6 10.5 0.0 2.8 3 0 0 3 3 3 0 YlqD protein Opy2 PF09463.10 KUM63804.1 - 2.9e-08 33.9 23.0 5.4e-08 33.0 23.0 1.5 1 0 0 1 1 1 1 Opy2 protein SKG6 PF08693.10 KUM63804.1 - 0.012 15.0 2.6 0.031 13.7 2.6 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CcmD PF04995.14 KUM63804.1 - 0.14 12.2 0.5 0.28 11.3 0.5 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Syndecan PF01034.20 KUM63804.1 - 0.22 11.4 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain IDO PF01231.18 KUM63805.1 - 4.2e-90 302.6 0.0 4.8e-90 302.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 KUM63805.1 - 0.12 11.1 0.0 0.25 10.0 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) Aminotran_5 PF00266.19 KUM63806.1 - 4.9e-92 308.8 0.0 6e-92 308.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KUM63806.1 - 6.6e-05 22.3 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KUM63806.1 - 0.0002 20.8 0.0 0.0011 18.4 0.0 2.1 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family COesterase PF00135.28 KUM63807.1 - 3.3e-12 46.1 0.0 5.8e-10 38.6 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Palm_thioest PF02089.15 KUM63808.1 - 1.5e-82 277.1 0.0 1.7e-82 276.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KUM63808.1 - 0.04 14.5 0.0 0.051 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.11 KUM63808.1 - 0.059 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) HTH_18 PF12833.7 KUM63808.1 - 0.13 12.5 0.0 42 4.5 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain STE2 PF02116.15 KUM63810.1 - 1.8e-104 349.0 21.6 2.2e-104 348.7 21.6 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR UEV PF05743.13 KUM63811.1 - 1.8e-39 134.4 0.1 3.3e-39 133.5 0.1 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KUM63811.1 - 4.9e-20 71.3 0.0 1.1e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 KUM63811.1 - 0.012 15.3 0.1 0.012 15.3 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme DUF3450 PF11932.8 KUM63811.1 - 0.25 10.6 3.2 0.42 9.9 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RWD PF05773.22 KUM63811.1 - 0.32 11.3 2.0 0.64 10.3 0.0 2.2 2 0 0 2 2 2 0 RWD domain CsbD PF05532.12 KUM63812.1 - 2.2e-16 59.5 20.1 6.8e-11 41.9 6.0 3.2 3 0 0 3 3 3 2 CsbD-like Methyltransf_16 PF10294.9 KUM63813.1 - 6.8e-16 58.5 0.0 1.2e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KUM63813.1 - 0.0057 16.5 0.0 0.0083 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KUM63813.1 - 0.19 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TFIIA PF03153.13 KUM63814.1 - 0.61 10.0 4.9 0.63 10.0 4.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F-box_4 PF15966.5 KUM63816.1 - 0.00086 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 KUM63816.1 - 0.049 13.5 0.3 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KUM63816.1 - 0.09 12.7 3.3 0.31 11.0 0.0 2.9 3 0 0 3 3 3 0 F-box domain DUF3712 PF12505.8 KUM63817.1 - 4.8e-28 97.9 1.0 1.1e-27 96.7 1.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) zf-C2H2 PF00096.26 KUM63819.1 - 0.0043 17.4 0.5 1.6 9.4 0.0 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type GluR_Homer-bdg PF10606.9 KUM63820.1 - 0.12 12.6 5.0 1.3 9.3 2.5 2.7 2 1 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor Med31 PF05669.12 KUM63822.1 - 2.7e-31 107.4 0.0 3.2e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 SOH1 Pal1 PF08316.11 KUM63823.1 - 3.2e-46 157.5 1.6 2.6e-45 154.6 1.6 2.5 1 1 0 1 1 1 1 Pal1 cell morphology protein COesterase PF00135.28 KUM63826.1 - 1.4e-96 324.4 0.1 1.7e-96 324.1 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KUM63826.1 - 8.8e-06 25.7 0.1 0.0045 16.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KUM63826.1 - 0.0084 15.6 0.1 0.016 14.7 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family NDUF_B7 PF05676.13 KUM63827.1 - 5.6e-27 93.2 7.0 6.7e-27 93.0 7.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KUM63827.1 - 0.0032 17.4 2.0 0.0039 17.2 2.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GCS PF03074.16 KUM63828.1 - 1.3e-176 587.4 0.0 1.6e-176 587.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF1560 PF07597.11 KUM63828.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) Cytochrom_B561 PF03188.16 KUM63828.1 - 0.19 11.8 0.0 6.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 Phage_Mu_Gp45 PF06890.12 KUM63829.1 - 0.025 14.3 0.1 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage Mu Gp45 protein MCM PF00493.23 KUM63831.1 - 4.5e-100 333.4 0.0 6.7e-100 332.8 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KUM63831.1 - 9.9e-38 128.8 0.2 1.8e-37 128.0 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KUM63831.1 - 1.2e-30 106.8 38.9 1.2e-30 106.8 38.9 2.1 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 KUM63831.1 - 1.9e-13 50.9 0.1 7.6e-13 49.0 0.1 2.0 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 KUM63831.1 - 1.7e-08 34.8 0.1 4.2e-08 33.5 0.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KUM63831.1 - 5.7e-08 32.4 0.1 6.2e-06 25.8 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KUM63831.1 - 9.5e-05 22.4 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KUM63831.1 - 0.0036 17.0 0.2 0.03 14.0 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KUM63831.1 - 0.012 15.4 0.1 0.13 12.1 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zn_ribbon_2 PF12674.7 KUM63831.1 - 0.027 15.1 0.2 0.074 13.7 0.2 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain AAA_16 PF13191.6 KUM63831.1 - 3.6 7.9 6.9 1.3 9.4 0.9 3.2 3 1 0 3 3 3 0 AAA ATPase domain Ank_2 PF12796.7 KUM63832.1 - 1.4e-10 41.6 1.9 0.00069 20.2 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM63832.1 - 7.8e-09 35.9 0.4 0.00017 22.1 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM63832.1 - 8.7e-08 32.3 0.7 0.00025 21.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM63832.1 - 1.3e-07 31.3 0.8 0.0025 18.2 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 KUM63832.1 - 1.7e-07 31.4 0.7 1.3e-05 25.4 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.13 KUM63832.1 - 6.8e-05 22.7 0.3 0.00059 19.7 0.0 2.6 3 0 0 3 3 3 1 KilA-N domain RskA PF10099.9 KUM63832.1 - 0.01 16.1 3.3 0.01 16.1 3.3 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA HALZ PF02183.18 KUM63832.1 - 0.12 12.6 2.8 5.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper TrmB PF01978.19 KUM63832.1 - 0.14 12.1 0.1 15 5.5 0.0 3.3 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB KTI12 PF08433.10 KUM63834.1 - 1.1e-63 215.3 0.0 1.9e-63 214.5 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KUM63834.1 - 0.044 13.9 0.3 0.11 12.7 0.3 1.7 1 0 0 1 1 1 0 AAA domain TraV PF09676.10 KUM63834.1 - 7.7 7.5 7.8 0.46 11.5 0.9 2.3 3 0 0 3 3 3 0 Type IV conjugative transfer system lipoprotein (TraV) Peptidase_C14 PF00656.22 KUM63835.1 - 3.5e-51 174.5 0.0 4.7e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DUF2236 PF09995.9 KUM63836.1 - 1.4e-37 130.1 3.2 1.8e-37 129.7 3.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) MDMPI_C PF07398.11 KUM63836.1 - 0.047 14.6 0.0 0.13 13.2 0.0 1.7 1 0 0 1 1 1 0 MDMPI C-terminal domain MIS13 PF08202.11 KUM63837.1 - 2.6e-45 155.0 2.0 5.8e-45 153.9 2.0 1.6 1 0 0 1 1 1 1 Mis12-Mtw1 protein family AT_hook PF02178.19 KUM63837.1 - 0.04 13.8 14.9 0.79 9.8 2.9 3.6 2 0 0 2 2 2 0 AT hook motif DivIC PF04977.15 KUM63837.1 - 0.1 12.4 1.3 0.12 12.2 0.2 1.7 2 0 0 2 2 2 0 Septum formation initiator ABC_tran_CTD PF16326.5 KUM63837.1 - 1.4 9.2 6.6 0.15 12.3 0.9 2.3 3 0 0 3 3 3 0 ABC transporter C-terminal domain PS_Dcarbxylase PF02666.15 KUM63838.1 - 4.1e-54 183.2 0.0 6.7e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KUM63838.1 - 0.0027 18.0 0.0 0.0055 17.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.32 KUM63838.1 - 0.016 14.7 0.2 0.078 12.6 0.1 2.3 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 KUM63838.1 - 0.16 11.5 0.0 0.57 9.8 0.0 2.0 1 0 0 1 1 1 0 EF hand ThrE PF06738.12 KUM63840.1 - 2.2e-74 249.9 16.2 2.3e-68 230.2 4.6 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KUM63840.1 - 5.3e-10 39.5 9.4 5.3e-10 39.5 9.4 3.0 3 1 0 3 3 3 2 Threonine/Serine exporter, ThrE AnkUBD PF18418.1 KUM63840.1 - 0.15 12.2 0.0 0.68 10.1 0.0 2.1 2 0 0 2 2 2 0 Ankyrin ubiquitin-binding domain Pkinase PF00069.25 KUM63841.1 - 2.3e-64 217.3 0.0 2.9e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM63841.1 - 5.4e-30 104.5 0.0 8.2e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KUM63841.1 - 0.0025 16.8 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KUM63841.1 - 0.15 12.0 0.0 0.94 9.4 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-UBR PF02207.20 KUM63842.1 - 3.9e-13 49.4 8.3 3.9e-13 49.4 8.3 3.5 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) RR_TM4-6 PF06459.12 KUM63842.1 - 2.4 7.9 11.3 4.5 7.0 11.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 KUM63842.1 - 7.7 5.2 10.8 78 1.9 11.8 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 C2 PF00168.30 KUM63843.1 - 2e-18 66.5 0.0 3.5e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain Sugar_tr PF00083.24 KUM63844.1 - 6.4e-92 308.8 10.1 8.2e-92 308.4 10.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM63844.1 - 2.7e-39 135.1 56.5 5.6e-35 120.9 29.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KUM63844.1 - 2e-07 30.6 3.4 2e-07 30.6 3.4 2.7 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB PsbX PF06596.11 KUM63844.1 - 0.074 13.1 0.5 0.074 13.1 0.5 4.1 4 0 0 4 4 4 0 Photosystem II reaction centre X protein (PsbX) PEP_mutase PF13714.6 KUM63845.1 - 2.9e-45 154.6 0.7 3.3e-45 154.4 0.7 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KUM63845.1 - 3.1e-18 65.6 0.1 4.5e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DUF3605 PF12239.8 KUM63847.1 - 1.5e-56 190.9 0.5 1.9e-56 190.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Hist_deacetyl PF00850.19 KUM63848.1 - 4.5e-77 259.5 0.1 5.8e-77 259.2 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain SNF2_N PF00176.23 KUM63849.1 - 4.4e-49 167.1 0.0 7.5e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 KUM63849.1 - 1.4e-27 95.6 0.9 2.4e-27 94.8 0.1 2.0 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 KUM63849.1 - 5.6e-21 75.0 0.0 2.2e-18 66.6 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM63849.1 - 7.8e-09 35.8 0.0 2.4e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KUM63849.1 - 5.2e-06 25.9 0.0 1.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 KUM63849.1 - 0.0096 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ssu72 PF04722.13 KUM63850.1 - 4.7e-80 267.7 0.0 5.5e-80 267.4 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Mito_fiss_reg PF05308.11 KUM63850.1 - 0.69 9.9 4.4 1 9.4 4.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 KUM63850.1 - 1.1 9.3 5.6 1.9 8.5 5.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 VIR_N PF15912.5 KUM63850.1 - 1.3 8.5 4.0 2 7.9 4.0 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal CAP_N PF01213.19 KUM63850.1 - 6.3 6.2 11.4 9.4 5.6 11.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Tom37 PF10568.9 KUM63852.1 - 1.5e-39 135.1 0.3 2.7e-39 134.3 0.3 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KUM63852.1 - 3.7e-07 30.8 0.0 8.7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KUM63852.1 - 1.7e-06 27.7 0.1 5.7e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain PP2C PF00481.21 KUM63853.1 - 1.1e-46 159.6 0.2 1.3e-46 159.3 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KUM63853.1 - 4.7e-07 29.9 0.2 0.0062 16.5 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KUM63853.1 - 3.2e-06 26.9 0.1 3.8e-05 23.4 0.0 2.4 1 1 0 2 2 2 1 Protein phosphatase 2C DUF5548 PF17702.1 KUM63853.1 - 0.0013 18.5 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5548) Oxysterol_BP PF01237.18 KUM63854.1 - 2.1e-90 303.3 0.0 4.2e-81 272.7 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein DUF4996 PF16387.5 KUM63854.1 - 0.11 12.9 0.1 0.24 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function Ctr PF04145.15 KUM63855.1 - 2e-41 142.1 0.0 3.7e-41 141.2 0.0 1.4 1 1 0 1 1 1 1 Ctr copper transporter family Oxidored_q3 PF00499.20 KUM63855.1 - 0.00065 19.4 1.7 0.0043 16.8 2.6 1.7 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 RNase_PH PF01138.21 KUM63856.1 - 4.4e-32 111.3 0.8 7.2e-32 110.7 0.2 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 adh_short_C2 PF13561.6 KUM63857.1 - 2.3e-52 177.9 0.0 3.1e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM63857.1 - 2.6e-46 157.5 0.1 3.2e-46 157.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM63857.1 - 6.3e-09 36.0 0.0 9.6e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KUM63857.1 - 0.0036 16.7 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 KUM63857.1 - 0.017 14.6 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KUM63857.1 - 0.049 13.1 0.0 0.075 12.5 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF952 PF06108.12 KUM63858.1 - 8.7e-21 73.7 0.0 1.1e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) IMPDH PF00478.25 KUM63860.1 - 1.9e-127 425.0 4.8 2.3e-127 424.7 4.8 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KUM63860.1 - 1.6e-17 63.7 0.1 4.7e-09 36.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 KUM63860.1 - 1.6e-05 24.1 0.8 3.3e-05 23.1 0.6 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KUM63860.1 - 4.8e-05 22.9 6.1 0.019 14.3 4.9 2.6 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 KUM63860.1 - 0.0026 17.3 3.4 0.037 13.5 0.3 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein Aldolase PF01081.19 KUM63860.1 - 0.017 14.6 1.0 0.05 13.0 0.2 2.1 2 0 0 2 2 2 0 KDPG and KHG aldolase PK PF00224.21 KUM63860.1 - 0.043 12.7 0.0 0.13 11.1 0.0 1.7 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain YpsA PF06908.11 KUM63860.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family Ribosomal_S21e PF01249.18 KUM63861.1 - 8.4e-41 138.0 0.0 1.1e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S21e NUDIX PF00293.28 KUM63862.1 - 3.4e-07 30.3 0.0 1.3e-06 28.5 0.0 2.0 1 1 1 2 2 2 1 NUDIX domain NAD_binding_9 PF13454.6 KUM63862.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding tRNA-synt_2d PF01409.20 KUM63863.1 - 2.9e-87 292.2 0.0 4.1e-87 291.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KUM63863.1 - 5.2e-15 55.5 1.6 5.4e-15 55.4 0.3 1.8 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KUM63863.1 - 1.3e-08 34.5 0.0 2.9e-07 30.2 0.0 2.3 1 1 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 KUM63863.1 - 7.5e-05 22.6 5.5 0.00026 20.9 5.5 2.0 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 KUM63863.1 - 0.00067 18.8 0.1 0.014 14.5 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 KUM63863.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Androgen_recep PF02166.16 KUM63863.1 - 0.19 10.5 0.6 0.3 9.9 0.6 1.2 1 0 0 1 1 1 0 Androgen receptor RasGAP PF00616.19 KUM63864.1 - 1.2e-47 162.3 0.0 3.6e-47 160.8 0.0 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KUM63864.1 - 1.1e-45 155.2 4.5 1.1e-45 155.2 4.5 2.7 2 1 0 2 2 2 1 RasGAP C-terminus CH PF00307.31 KUM63864.1 - 5.3e-11 42.7 0.3 1.8e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 KUM63864.1 - 3.2e-10 38.9 55.7 0.9 9.5 0.1 15.7 17 0 0 17 17 17 9 IQ calmodulin-binding motif Dodecin PF07311.12 KUM63864.1 - 0.15 12.3 0.1 95 3.4 0.0 3.9 4 0 0 4 4 4 0 Dodecin ENTH PF01417.20 KUM63865.1 - 4.3e-45 152.8 0.2 6.3e-45 152.3 0.2 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KUM63865.1 - 0.0011 18.0 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 ANTH domain Isochorismatase PF00857.20 KUM63866.1 - 3e-24 86.2 0.2 6e-24 85.2 0.2 1.5 1 1 0 1 1 1 1 Isochorismatase family DUF1131 PF06572.12 KUM63866.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) FmdA_AmdA PF03069.15 KUM63867.1 - 1.4e-55 188.7 0.0 3.7e-32 111.6 0.0 2.1 1 1 1 2 2 2 2 Acetamidase/Formamidase family DUF948 PF06103.11 KUM63868.1 - 0.0016 18.7 0.2 3.7 7.9 0.0 2.8 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF948) Apolipoprotein PF01442.18 KUM63868.1 - 0.0054 16.6 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF3618 PF12277.8 KUM63868.1 - 0.026 14.8 2.0 0.026 14.8 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) ERAP1_C PF11838.8 KUM63868.1 - 0.035 13.7 0.3 0.06 12.9 0.2 1.4 1 1 0 1 1 1 0 ERAP1-like C-terminal domain HAUS5 PF14817.6 KUM63868.1 - 0.067 12.0 0.0 0.18 10.5 0.0 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 5 TetR_C_22 PF17928.1 KUM63868.1 - 0.069 13.5 0.4 8.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF1664 PF07889.12 KUM63868.1 - 0.13 12.3 0.2 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SfLAP PF11139.8 KUM63871.1 - 0.0068 15.9 2.5 0.0068 15.9 2.5 1.6 2 0 0 2 2 2 1 Sap, sulfolipid-1-addressing protein MARVEL PF01284.23 KUM63871.1 - 0.016 15.3 20.6 0.02 14.9 20.6 1.1 1 0 0 1 1 1 0 Membrane-associating domain DUF412 PF04217.13 KUM63871.1 - 0.62 10.0 2.9 0.45 10.4 1.3 1.6 1 1 1 2 2 2 0 Protein of unknown function, DUF412 MMgT PF10270.9 KUM63871.1 - 0.64 10.4 3.6 3.1 8.2 0.9 2.1 2 0 0 2 2 2 0 Membrane magnesium transporter TIL PF01826.17 KUM63872.1 - 5.1 7.4 18.7 38 4.6 6.6 2.6 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain HMG-CoA_red PF00368.18 KUM63873.1 - 1.9e-137 458.2 4.6 2.4e-137 457.8 4.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KUM63873.1 - 2.4e-51 173.7 0.3 4.3e-51 172.9 0.3 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KUM63873.1 - 4.5e-13 49.3 3.1 2.6e-12 46.8 3.1 2.3 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KUM63873.1 - 6.2e-06 24.6 2.5 6.2e-06 24.6 2.5 1.4 2 0 0 2 2 2 1 Patched family Pro_isomerase PF00160.21 KUM63875.1 - 2.6e-42 144.8 0.1 2.6e-42 144.8 0.1 1.4 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GIT_SHD PF08518.11 KUM63876.1 - 3e-25 87.5 5.7 1.8e-14 53.0 0.5 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 KUM63876.1 - 0.00019 21.5 0.2 0.00019 21.5 0.2 3.0 3 0 0 3 3 3 1 G protein-coupled receptor kinase-interacting protein 1 C term Fez1 PF06818.15 KUM63876.1 - 0.013 16.0 9.4 0.013 16.0 9.4 2.9 2 1 1 3 3 3 0 Fez1 CENP-F_leu_zip PF10473.9 KUM63876.1 - 0.29 11.2 27.4 2.3 8.3 13.7 2.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1843 PF08898.10 KUM63876.1 - 0.46 11.0 2.0 15 6.2 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) BRE1 PF08647.11 KUM63876.1 - 4 7.6 23.0 0.056 13.5 5.5 3.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase ZapB PF06005.12 KUM63876.1 - 5.9 7.4 34.1 6.9 7.2 3.3 4.3 1 1 4 5 5 5 0 Cell division protein ZapB APG6_N PF17675.1 KUM63876.1 - 7.5 7.1 35.3 0.18 12.4 21.3 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 KUM63876.1 - 9.2 6.9 25.6 6.1 7.5 8.2 3.1 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UvrD-helicase PF00580.21 KUM63877.1 - 4.5e-62 210.4 3.8 1.9e-60 205.1 0.1 3.3 2 2 1 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KUM63877.1 - 5.3e-58 197.1 0.1 3.2e-57 194.5 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KUM63877.1 - 3.6e-31 108.5 0.0 1.1e-30 106.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain UvrD_C_2 PF13538.6 KUM63877.1 - 1.3e-14 53.7 0.1 3e-14 52.6 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KUM63877.1 - 1.2e-08 34.9 0.2 0.00021 21.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 KUM63877.1 - 8.5e-06 25.5 0.0 0.00022 20.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KUM63877.1 - 0.00064 19.5 0.8 0.25 11.0 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KUM63877.1 - 0.0013 19.0 0.6 0.21 11.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain Rrp15p PF07890.12 KUM63877.1 - 0.0014 18.9 0.4 0.004 17.5 0.1 1.9 2 0 0 2 2 2 1 Rrp15p AAA_11 PF13086.6 KUM63877.1 - 0.0019 18.1 1.8 0.0072 16.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KUM63877.1 - 0.46 10.9 2.2 1.1 9.6 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain SLAIN PF15301.6 KUM63877.1 - 0.55 9.4 8.9 1.3 8.1 8.9 1.6 1 0 0 1 1 1 0 SLAIN motif-containing family Sugar_tr PF00083.24 KUM63878.1 - 4.7e-55 187.2 26.5 7.8e-54 183.2 26.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM63878.1 - 4.3e-15 55.5 37.8 3.2e-08 32.9 14.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zip PF02535.22 KUM63879.1 - 3.6e-65 220.4 10.3 4.1e-65 220.2 10.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Cation_ATPase_C PF00689.21 KUM63879.1 - 0.087 12.5 7.6 0.59 9.8 0.7 2.7 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Cyt-b5 PF00173.28 KUM63880.1 - 2.5e-15 56.4 0.0 3.9e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FKBP_C PF00254.28 KUM63881.1 - 4.7e-33 113.4 0.0 5.6e-33 113.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SH3_1 PF00018.28 KUM63882.1 - 8.6e-11 41.3 0.1 2e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KUM63882.1 - 2.5e-09 36.8 0.1 5e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KUM63882.1 - 9.4e-08 31.6 0.0 1.9e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF908 PF06012.12 KUM63882.1 - 0.96 8.8 3.9 1.9 7.8 3.9 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Peptidase_M20 PF01546.28 KUM63883.1 - 4.4e-31 108.2 0.0 5.6e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KUM63883.1 - 2.3e-12 46.8 0.0 3.6e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KUM63883.1 - 0.061 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M28 PLDc PF00614.22 KUM63884.1 - 1.9e-14 53.1 0.2 1.2e-06 28.4 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KUM63884.1 - 2.1e-13 50.3 0.0 1.4e-06 28.2 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 KUM63884.1 - 1.1e-07 31.8 0.1 6.9e-07 29.2 0.0 2.4 2 1 0 2 2 2 1 PX domain Hydrolase_4 PF12146.8 KUM63885.1 - 0.13 11.5 0.0 0.89 8.8 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ribosomal_L27A PF00828.19 KUM63886.1 - 2.7e-10 41.0 0.0 2.8e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Helicase_C_2 PF13307.6 KUM63888.1 - 1.1e-56 191.7 0.0 2.7e-56 190.4 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KUM63888.1 - 1.9e-50 170.9 0.0 3.9e-50 169.9 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KUM63888.1 - 0.0033 17.1 0.0 0.0085 15.8 0.0 1.7 1 0 0 1 1 1 1 Helical and beta-bridge domain Methyltrn_RNA_4 PF09936.9 KUM63888.1 - 0.077 12.8 0.1 8.3 6.2 0.0 2.5 1 1 1 2 2 2 0 SAM-dependent RNA methyltransferase TTKRSYEDQ PF10212.9 KUM63888.1 - 1.2 8.0 4.7 7.2 5.5 1.6 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein MAJIN PF15077.6 KUM63888.1 - 7.6 6.2 6.3 24 4.6 4.3 2.2 2 0 0 2 2 2 0 Membrane-anchored junction protein YccV-like PF08755.11 KUM63889.1 - 4.2e-29 100.9 0.1 9.8e-29 99.8 0.1 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 KUM63889.1 - 1.8e-10 40.6 0.0 3.3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 KUM63889.1 - 7.6e-08 32.1 1.0 2.3e-07 30.6 1.0 1.9 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.11 KUM63889.1 - 8e-05 23.1 1.6 0.00015 22.3 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 KUM63889.1 - 0.053 13.4 0.4 0.053 13.4 0.4 2.0 2 0 0 2 2 2 0 F-box domain Zn_clus PF00172.18 KUM63890.1 - 1e-08 35.2 13.2 1.7e-08 34.5 13.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.20 KUM63891.1 - 1.4e-59 201.8 0.0 1.6e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Ras PF00071.22 KUM63892.1 - 2.9e-34 118.0 0.0 5.6e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KUM63892.1 - 3.8e-05 23.9 0.0 9.7e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM63892.1 - 0.04 13.4 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.27 KUM63892.1 - 0.12 11.8 0.0 0.6 9.6 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain LETM1 PF07766.13 KUM63894.1 - 7e-09 35.4 0.0 0.00083 18.8 0.0 2.3 2 0 0 2 2 2 2 LETM1-like protein PAS_9 PF13426.7 KUM63895.1 - 5.5e-27 94.0 0.0 8.2e-20 71.0 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 KUM63895.1 - 3.6e-20 72.0 0.0 6e-12 45.7 0.0 3.9 4 0 0 4 4 4 3 PAS fold GATA PF00320.27 KUM63895.1 - 2.2e-14 52.8 7.3 6.5e-14 51.2 7.3 1.9 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 KUM63895.1 - 4.8e-12 45.9 0.0 0.00022 21.2 0.0 3.6 3 1 0 3 3 3 2 PAS fold PAS_4 PF08448.10 KUM63895.1 - 5.8e-09 36.2 0.0 0.0025 18.0 0.0 3.7 4 0 0 4 4 4 3 PAS fold PAS_8 PF13188.7 KUM63895.1 - 0.0017 18.3 0.0 0.094 12.8 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 KUM63895.1 - 0.0037 17.4 0.0 0.085 13.0 0.0 2.9 3 0 0 3 3 3 1 PAS domain Nudix_N_2 PF14803.6 KUM63895.1 - 0.095 12.6 1.3 0.31 11.0 1.3 1.9 1 0 0 1 1 1 0 Nudix N-terminal Cys_Met_Meta_PP PF01053.20 KUM63896.1 - 9.9e-34 116.5 0.0 1.3e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KUM63896.1 - 0.00031 20.0 0.0 0.00046 19.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Nrap_D4 PF17405.2 KUM63897.1 - 2.9e-62 209.8 0.0 5.2e-62 209.0 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KUM63897.1 - 3.2e-57 192.8 1.0 5.9e-57 192.0 1.0 1.4 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 KUM63897.1 - 1.6e-48 164.3 0.0 3.4e-46 156.8 0.0 2.4 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 KUM63897.1 - 1.3e-44 152.1 0.1 2.4e-44 151.2 0.1 1.4 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap PF03813.14 KUM63897.1 - 9.4e-39 132.9 0.1 4e-38 130.8 0.0 2.1 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D6 PF17407.2 KUM63897.1 - 3.3e-28 98.6 0.0 6.9e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 QRPTase_C PF01729.19 KUM63898.1 - 1.4e-46 158.4 0.3 6.1e-45 153.0 0.3 2.0 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KUM63898.1 - 1.3e-22 79.7 0.0 3.3e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF768 PF05589.11 KUM63898.1 - 0.27 11.2 1.3 48 4.1 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF768) Cnn_1N PF07989.11 KUM63899.1 - 5.1e-23 81.0 9.7 5.1e-23 81.0 9.7 12.2 8 1 3 12 12 12 2 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 KUM63899.1 - 2.8e-21 75.5 31.4 1.4e-17 63.7 16.2 12.7 12 3 1 14 14 14 2 Micro-tubular organiser Mto1 C-term Mto2-binding region MRP-L20 PF12824.7 KUM63901.1 - 1e-62 211.1 4.3 1.2e-62 210.9 4.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 KUM63901.1 - 0.00093 19.3 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Neugrin HTH_32 PF13565.6 KUM63901.1 - 0.0014 19.2 0.7 0.077 13.6 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain CtsR PF05848.11 KUM63901.1 - 0.054 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 CtsR N-terminal HTH domain Cep3 PF16846.5 KUM63902.1 - 6.4e-06 24.9 0.0 1.4e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B PhyH PF05721.13 KUM63903.1 - 0.0015 18.8 0.1 0.0024 18.2 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KUM63903.1 - 0.01 14.7 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.6 KUM63903.1 - 0.13 13.2 0.0 0.29 12.1 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Sel1 PF08238.12 KUM63904.1 - 6.3e-18 64.8 17.4 5.8e-07 30.0 0.1 6.6 7 0 0 7 7 7 4 Sel1 repeat TPR_1 PF00515.28 KUM63904.1 - 0.00019 21.1 0.1 0.0013 18.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KUM63904.1 - 0.051 14.4 1.8 0.15 12.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KUM63904.1 - 0.1 12.7 0.0 0.1 12.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KUM63905.1 - 4.5e-87 292.8 24.0 5.3e-87 292.6 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM63905.1 - 1.5e-25 89.9 34.5 6.3e-20 71.4 16.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KUM63905.1 - 0.00073 18.9 11.0 0.00073 18.9 11.0 1.9 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Complex1_LYR PF05347.15 KUM63906.1 - 5.6e-10 39.1 0.4 7.4e-10 38.7 0.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF1151 PF06625.11 KUM63907.1 - 0.0021 18.0 4.1 0.0021 18.0 4.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1151) DUF1749 PF08538.10 KUM63907.1 - 0.08 12.0 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) NPAT_C PF15712.5 KUM63907.1 - 0.12 11.0 0.4 0.17 10.5 0.4 1.1 1 0 0 1 1 1 0 NPAT C terminus DUF5542 PF17696.1 KUM63907.1 - 0.97 9.6 3.9 0.24 11.5 0.4 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5542) zf-CCCH PF00642.24 KUM63908.1 - 3.5e-12 45.9 10.4 2.5e-06 27.3 1.9 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KUM63908.1 - 2.6e-10 39.9 9.0 1.5e-06 27.8 2.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KUM63908.1 - 3.3e-09 36.5 16.1 4.2e-05 23.4 1.8 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KUM63908.1 - 4.1e-09 37.1 5.2 0.00034 21.3 0.5 2.5 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 KUM63908.1 - 0.00052 20.2 0.2 0.00093 19.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KUM63908.1 - 0.003 18.0 13.9 0.18 12.3 3.2 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger CENP-F_leu_zip PF10473.9 KUM63909.1 - 5e-05 23.3 1.7 7.3e-05 22.8 1.7 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mitofilin PF09731.9 KUM63909.1 - 0.0065 15.4 3.3 0.0073 15.2 3.3 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein ABC_tran_CTD PF16326.5 KUM63909.1 - 0.01 16.0 8.6 0.23 11.7 3.4 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain Leu_zip PF15294.6 KUM63909.1 - 0.011 15.3 0.3 0.012 15.2 0.3 1.1 1 0 0 1 1 1 0 Leucine zipper Prefoldin_2 PF01920.20 KUM63909.1 - 0.017 15.1 6.9 0.13 12.2 0.6 2.6 2 1 1 3 3 3 0 Prefoldin subunit Herpes_BLRF2 PF05812.12 KUM63909.1 - 0.018 15.1 3.3 0.087 13.0 0.1 2.2 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DUF5082 PF16888.5 KUM63909.1 - 0.019 15.2 4.9 0.24 11.7 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) PspA_IM30 PF04012.12 KUM63909.1 - 0.025 14.2 3.4 0.043 13.4 2.5 1.7 1 1 0 1 1 1 0 PspA/IM30 family HTH_39 PF14090.6 KUM63909.1 - 0.038 13.7 0.3 0.23 11.2 0.3 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain Wbp11 PF09429.10 KUM63909.1 - 0.058 13.8 6.2 1.4 9.4 1.3 2.4 1 1 1 2 2 2 0 WW domain binding protein 11 DUF4407 PF14362.6 KUM63909.1 - 0.06 12.7 0.2 0.081 12.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LPP PF04728.13 KUM63909.1 - 0.087 13.2 0.4 9.9 6.6 0.2 2.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper FapA PF03961.13 KUM63909.1 - 0.089 11.4 0.4 0.12 11.0 0.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 KUM63909.1 - 0.095 13.1 0.8 13 6.2 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.11 KUM63909.1 - 0.15 12.1 6.3 3.6 7.7 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) CCDC-167 PF15188.6 KUM63909.1 - 0.19 12.1 7.6 0.7 10.3 1.3 2.5 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 DUF4140 PF13600.6 KUM63909.1 - 0.22 12.0 7.4 1.8 9.1 0.7 2.5 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) TSC22 PF01166.18 KUM63909.1 - 0.24 11.7 4.9 6.6 7.1 0.1 2.6 2 1 1 3 3 2 0 TSC-22/dip/bun family ZapB PF06005.12 KUM63909.1 - 0.3 11.6 7.5 0.72 10.3 0.9 2.2 1 1 1 2 2 2 0 Cell division protein ZapB Siah-Interact_N PF09032.11 KUM63909.1 - 0.32 11.3 7.1 0.62 10.4 0.5 2.8 1 1 2 3 3 3 0 Siah interacting protein, N terminal Uds1 PF15456.6 KUM63909.1 - 0.33 11.1 6.9 0.11 12.6 3.2 2.0 2 1 0 2 2 2 0 Up-regulated During Septation Swi5 PF07061.11 KUM63909.1 - 0.44 10.7 4.9 7.8 6.7 0.7 2.3 1 1 1 2 2 2 0 Swi5 APG6_N PF17675.1 KUM63909.1 - 0.44 11.1 11.4 0.044 14.3 4.1 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 KUM63909.1 - 0.48 10.7 5.2 1.2 9.4 3.1 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Jnk-SapK_ap_N PF09744.9 KUM63909.1 - 0.59 10.3 5.3 1.1 9.5 5.3 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 ADIP PF11559.8 KUM63909.1 - 0.85 9.7 5.5 1.2 9.2 2.1 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 KUM63909.1 - 2.3 8.1 8.5 10 6.0 4.6 2.8 2 1 0 2 2 2 0 Septum formation initiator TPR_MLP1_2 PF07926.12 KUM63909.1 - 4 7.5 8.8 3.3 7.8 1.0 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Histone_H2A_C PF16211.5 KUM63910.1 - 4.5e-21 74.3 2.6 8e-21 73.5 2.6 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KUM63910.1 - 6.6e-17 62.1 0.0 8.9e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KUM63910.1 - 9.5e-06 25.8 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_C54 PF03416.19 KUM63911.1 - 1.1e-63 215.3 0.0 1.3e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Histone PF00125.24 KUM63912.1 - 3.6e-21 75.9 0.3 4.4e-21 75.6 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KUM63912.1 - 0.00029 21.1 1.1 0.0004 20.6 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KUM63912.1 - 0.0005 20.5 0.0 0.00083 19.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KUM63912.1 - 0.036 13.7 0.1 0.082 12.5 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain DnaJ PF00226.31 KUM63913.1 - 4e-22 78.1 3.3 1e-21 76.8 1.2 2.7 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 KUM63913.1 - 3.9e-16 57.8 1.6 0.12 12.5 0.0 8.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KUM63913.1 - 1e-15 56.8 0.0 0.0013 18.4 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KUM63913.1 - 1.4e-11 44.8 8.1 7.9e-06 26.3 1.1 4.7 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KUM63913.1 - 1.5e-11 44.2 9.2 0.0032 17.6 0.0 5.3 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KUM63913.1 - 6.1e-11 42.2 11.6 0.093 13.6 0.0 7.7 4 3 4 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KUM63913.1 - 4.2e-10 39.0 1.1 0.36 11.1 0.0 7.3 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KUM63913.1 - 1.5e-07 31.6 4.1 7.6 7.4 0.0 7.6 7 1 0 7 7 7 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KUM63913.1 - 9.4e-06 25.3 2.4 0.016 14.8 0.0 2.7 2 0 0 2 2 2 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_17 PF13431.6 KUM63913.1 - 8.9e-05 22.6 0.1 0.28 11.7 0.0 5.2 5 1 1 6 6 5 1 Tetratricopeptide repeat PknG_TPR PF16918.5 KUM63913.1 - 0.00048 19.0 0.2 0.015 14.1 0.0 2.7 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_7 PF13176.6 KUM63913.1 - 0.0053 16.7 4.0 57 4.1 0.2 5.8 5 2 1 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KUM63913.1 - 0.017 14.8 0.0 1.6 8.5 0.0 4.0 4 1 1 5 5 5 0 TPR repeat RPT PF13446.6 KUM63913.1 - 0.027 14.4 0.0 0.39 10.7 0.0 2.9 2 1 0 2 2 2 0 A repeated domain in UCH-protein DUF3811 PF11656.8 KUM63913.1 - 0.081 13.3 0.2 0.081 13.3 0.2 2.5 2 0 0 2 2 2 0 YjbD family (DUF3811) Fis1_TPR_C PF14853.6 KUM63913.1 - 0.098 12.7 0.3 6 7.0 0.1 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Na_Ca_ex_C PF16494.5 KUM63913.1 - 0.2 12.1 0.2 0.2 12.1 0.2 2.7 3 0 0 3 3 3 0 C-terminal extension of sodium/calcium exchanger domain TPR_16 PF13432.6 KUM63913.1 - 0.26 12.0 24.5 2.1 9.1 1.0 6.4 8 1 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM63913.1 - 0.26 11.5 13.6 1.2 9.4 0.1 5.0 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TipAS PF07739.13 KUM63913.1 - 1.2 9.7 13.7 0.81 10.3 0.3 4.1 3 1 1 4 4 4 0 TipAS antibiotic-recognition domain 2-oxoacid_dh PF00198.23 KUM63914.1 - 3.3e-74 249.2 0.1 4.8e-74 248.7 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KUM63914.1 - 2.1e-17 62.7 1.8 2.1e-17 62.7 1.8 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD_3 PF13437.6 KUM63914.1 - 0.0019 18.9 0.2 0.34 11.6 0.0 2.4 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 KUM63914.1 - 0.0056 16.5 0.2 0.089 12.6 0.1 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like GCV_H PF01597.19 KUM63914.1 - 0.042 13.7 0.2 0.091 12.7 0.2 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein RnfC_N PF13375.6 KUM63914.1 - 0.047 13.7 0.2 0.39 10.7 0.1 2.2 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain SAGA-Tad1 PF12767.7 KUM63914.1 - 0.11 12.2 0.4 0.16 11.7 0.4 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DnaJ PF00226.31 KUM63915.1 - 4.3e-24 84.4 0.3 1.1e-23 83.2 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 KUM63915.1 - 3.3e-08 33.6 4.5 3.3e-08 33.6 4.5 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KUM63915.1 - 5.6e-06 26.6 3.8 5.6e-06 26.6 3.8 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KUM63915.1 - 4.6e-05 23.6 7.1 0.021 15.3 0.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KUM63915.1 - 6.5e-05 23.2 6.3 0.078 13.3 4.1 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KUM63915.1 - 0.00022 21.8 4.8 0.33 11.9 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-MYST PF17772.1 KUM63915.1 - 0.02 14.5 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 MYST family zinc finger domain DUF4303 PF14136.6 KUM63915.1 - 0.037 13.8 0.4 0.09 12.5 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) LIM PF00412.22 KUM63915.1 - 0.037 14.2 1.1 5.1 7.4 0.1 2.4 2 0 0 2 2 2 0 LIM domain MIEAP PF16026.5 KUM63915.1 - 0.057 13.6 3.1 0.13 12.4 2.5 1.8 1 1 0 1 1 1 0 Mitochondria-eating protein RPT PF13446.6 KUM63915.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.9 1 0 0 1 1 1 0 A repeated domain in UCH-protein Transcrip_act PF04949.13 KUM63915.1 - 0.22 11.4 0.0 0.22 11.4 0.0 3.0 2 1 0 3 3 3 0 Transcriptional activator zf-U1 PF06220.12 KUM63915.1 - 0.27 11.1 2.0 0.65 9.8 2.0 1.7 1 0 0 1 1 1 0 U1 zinc finger UPF0449 PF15136.6 KUM63915.1 - 0.33 11.4 3.6 0.43 11.1 1.8 2.2 2 0 0 2 2 1 0 Uncharacterised protein family UPF0449 Cytochrome_C7 PF14522.6 KUM63915.1 - 0.45 10.5 4.5 0.9 9.6 1.2 2.5 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c R3H PF01424.22 KUM63916.1 - 3.7e-14 52.4 0.0 7.5e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KUM63916.1 - 5.4e-10 39.0 0.3 1e-09 38.1 0.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KUM63916.1 - 0.00025 21.1 0.3 0.0007 19.6 0.3 1.8 1 0 0 1 1 1 1 G-patch domain PT PF04886.12 KUM63916.1 - 0.0028 17.2 1.6 0.0074 15.8 1.6 1.7 1 0 0 1 1 1 1 PT repeat PAP_assoc PF03828.19 KUM63917.1 - 0.029 14.6 0.0 0.38 11.0 0.0 2.4 1 1 0 1 1 1 0 Cid1 family poly A polymerase Glyco_transf_20 PF00982.21 KUM63918.1 - 9.8e-151 502.6 0.0 2.1e-150 501.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KUM63918.1 - 3.7e-83 278.2 0.0 6.3e-83 277.5 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase DEAD PF00270.29 KUM63919.1 - 4.5e-42 143.8 0.0 6.5e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM63919.1 - 6e-28 97.4 0.7 8.1e-27 93.8 0.5 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM63919.1 - 0.0087 16.1 0.0 0.024 14.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SMC_N PF02463.19 KUM63920.1 - 4e-24 85.3 0.5 1.3e-23 83.6 0.5 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KUM63920.1 - 4.2e-10 40.5 72.9 4.4e-10 40.4 34.5 5.1 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 KUM63920.1 - 6.9e-10 39.2 11.8 6.9e-10 39.2 11.8 3.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KUM63920.1 - 1.1e-07 31.9 5.7 5.3e-05 23.2 1.8 2.8 2 2 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KUM63920.1 - 0.00011 21.9 0.0 0.00034 20.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KUM63920.1 - 0.02 15.1 0.3 0.12 12.7 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 KUM63920.1 - 0.098 13.2 0.2 0.098 13.2 0.2 5.3 3 2 0 3 3 3 0 ABC transporter UNC-50 PF05216.13 KUM63921.1 - 9.9e-85 283.6 5.8 1.2e-84 283.3 5.8 1.0 1 0 0 1 1 1 1 UNC-50 family Sec7 PF01369.20 KUM63922.1 - 1.1e-27 97.0 0.0 2.5e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KUM63922.1 - 6.7e-20 71.6 0.3 2.3e-18 66.7 0.0 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain Tektin PF03148.14 KUM63922.1 - 0.09 11.5 0.1 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 Tektin family MFS_1 PF07690.16 KUM63923.1 - 8.6e-19 67.7 54.2 3.9e-16 58.9 30.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PP28 PF10252.9 KUM63924.1 - 1e-28 99.6 17.5 1e-28 99.6 17.5 3.2 3 0 0 3 3 3 1 Casein kinase substrate phosphoprotein PP28 AF-4 PF05110.13 KUM63924.1 - 5.3 5.0 31.1 6 4.8 31.1 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PCRF PF03462.18 KUM63925.1 - 4.1e-48 163.8 0.0 3e-47 161.0 0.0 2.1 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KUM63925.1 - 1.1e-33 115.6 1.1 2.4e-33 114.5 1.1 1.6 1 0 0 1 1 1 1 RF-1 domain Phage_tail_T PF06223.12 KUM63925.1 - 0.085 13.4 0.1 0.39 11.3 0.0 2.0 2 0 0 2 2 2 0 Minor tail protein T FYRC PF05965.14 KUM63925.1 - 0.12 12.6 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 F/Y rich C-terminus Mito_carr PF00153.27 KUM63926.1 - 2.9e-43 145.7 6.0 7.7e-19 67.4 0.2 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein PCMT PF01135.19 KUM63927.1 - 4.6e-62 209.5 0.0 6.6e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KUM63927.1 - 5.8e-09 35.9 0.0 9.5e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KUM63927.1 - 1.2e-06 28.6 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM63927.1 - 2.3e-06 28.2 0.0 4.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM63927.1 - 6.2e-06 26.2 0.0 8.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM63927.1 - 0.0004 21.0 0.0 0.00065 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM63927.1 - 0.018 15.8 0.0 0.03 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KUM63927.1 - 0.02 14.5 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 KUM63927.1 - 0.05 13.2 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KUM63927.1 - 0.088 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KUM63927.1 - 0.19 11.8 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Cation_ATPase_C PF00689.21 KUM63929.1 - 4.9e-41 140.4 16.7 1.9e-35 122.2 5.8 3.5 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KUM63929.1 - 1.1e-38 132.5 0.1 1.1e-38 132.5 0.1 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KUM63929.1 - 6.5e-23 80.6 0.0 1.2e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KUM63929.1 - 3.5e-19 69.9 0.0 1.2e-18 68.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KUM63929.1 - 2e-11 43.4 0.2 8.1e-10 38.2 0.0 2.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KUM63929.1 - 7.1e-05 22.7 0.2 0.012 15.3 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Ferlin_C PF16165.5 KUM63929.1 - 0.016 15.2 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 Ferlin C-terminus LptF_LptG PF03739.14 KUM63929.1 - 0.48 9.2 8.2 0.055 12.3 3.6 1.7 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG TPP_enzyme_N PF02776.18 KUM63930.1 - 2.3e-39 134.8 0.0 7.2e-39 133.1 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KUM63930.1 - 4.1e-20 72.1 0.0 1.1e-19 70.8 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KUM63930.1 - 6.8e-16 58.3 0.0 3.2e-15 56.1 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Inhibitor_I9 PF05922.16 KUM63931.1 - 0.0088 16.7 0.1 0.011 16.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF4926 PF16277.5 KUM63931.1 - 0.081 12.3 0.2 0.13 11.7 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4926) DUF2235 PF09994.9 KUM63932.1 - 2e-77 260.4 0.0 3e-77 259.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) PLDc_2 PF13091.6 KUM63933.1 - 4.1e-19 68.8 0.1 9.4e-13 48.2 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain Regulator_TrmB PF11495.8 KUM63933.1 - 0.0022 17.2 0.0 0.0037 16.5 0.0 1.3 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB PLDc PF00614.22 KUM63933.1 - 0.0032 17.6 0.0 0.82 9.9 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif MmgE_PrpD PF03972.14 KUM63934.1 - 1.2e-110 370.1 0.0 1.4e-110 369.9 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family BCDHK_Adom3 PF10436.9 KUM63935.1 - 1.2e-45 155.3 0.0 1.5e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KUM63935.1 - 1.4e-11 44.9 0.0 3e-11 43.8 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro_2_N PF02837.18 KUM63936.1 - 1e-11 45.0 0.0 2.6e-11 43.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KUM63936.1 - 4e-11 42.6 0.1 2.1e-09 36.9 0.1 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 KUM63936.1 - 5.8e-08 33.4 0.0 1.3e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 tify PF06200.14 KUM63936.1 - 0.11 11.8 0.5 0.23 10.8 0.5 1.5 1 0 0 1 1 1 0 tify domain KH_1 PF00013.29 KUM63937.1 - 1.3e-32 111.4 3.7 1.1e-08 34.7 0.0 6.6 6 0 0 6 6 6 5 KH domain Chitin_synth_2 PF03142.15 KUM63938.1 - 2.5e-240 798.6 0.9 3.5e-240 798.1 0.9 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KUM63938.1 - 4.2e-73 246.7 0.0 1.1e-64 218.8 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) Cyt-b5 PF00173.28 KUM63938.1 - 5.1e-18 65.0 0.1 3.4e-13 49.5 0.0 3.2 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 KUM63938.1 - 7.8e-15 54.5 0.1 9.4e-14 51.1 0.4 2.5 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 KUM63938.1 - 1.9e-09 37.8 0.0 6.4e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KUM63938.1 - 9.2e-09 35.5 5.6 2.3e-08 34.2 5.6 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 RsgA_GTPase PF03193.16 KUM63938.1 - 0.065 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KUM63938.1 - 0.084 13.3 0.1 0.29 11.5 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain Glycos_transf_2 PF00535.26 KUM63938.1 - 0.1 12.4 0.0 3 7.6 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 ABC_tran PF00005.27 KUM63938.1 - 0.2 12.1 0.4 1 9.9 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Chitin_synth_2 PF03142.15 KUM63939.1 - 2.2e-229 762.5 0.0 3e-229 762.0 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 KUM63939.1 - 1.5e-16 60.0 0.2 4.3e-16 58.6 0.2 1.8 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 KUM63939.1 - 1e-12 48.4 2.3 1e-12 48.4 2.3 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 KUM63939.1 - 1.4e-12 47.6 0.9 5.6e-07 29.6 0.1 3.0 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 KUM63939.1 - 6.5e-12 45.8 0.0 1.3e-10 41.5 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 KUM63939.1 - 4.2e-09 35.2 0.0 3.5e-08 32.1 0.0 1.9 1 1 1 2 2 2 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 KUM63939.1 - 0.0019 17.7 0.0 0.011 15.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KUM63939.1 - 0.007 16.2 0.0 0.22 11.3 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Jiv90 PF14901.6 KUM63939.1 - 0.072 13.3 2.7 3 8.0 0.4 2.7 2 1 0 2 2 2 0 Cleavage inducing molecular chaperone PH_3 PF14593.6 KUM63939.1 - 0.096 12.8 0.1 0.26 11.4 0.1 1.7 1 0 0 1 1 1 0 PH domain DUF3712 PF12505.8 KUM63940.1 - 9.3e-25 87.3 0.1 1.9e-24 86.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) DUF1279 PF06916.13 KUM63940.1 - 0.0082 16.7 0.0 0.019 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Mannosyl_trans3 PF11051.8 KUM63941.1 - 1.2e-55 188.8 0.0 5.6e-55 186.6 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative Sulfotransfer_4 PF17784.1 KUM63943.1 - 3.8e-58 196.9 0.0 6.3e-58 196.1 0.0 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KUM63943.1 - 0.0032 17.9 0.1 0.049 14.0 0.1 2.3 1 1 0 1 1 1 1 Sulfotransferase family DUF3843 PF12954.7 KUM63943.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) Sugar_tr PF00083.24 KUM63944.1 - 5.6e-98 328.7 17.7 6.4e-98 328.6 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM63944.1 - 7.8e-30 104.0 47.9 8.3e-26 90.7 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM63944.1 - 0.0056 15.2 0.7 0.0056 15.2 0.7 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) VIT1 PF01988.19 KUM63944.1 - 0.33 10.8 5.3 0.93 9.3 0.2 3.1 3 0 0 3 3 3 0 VIT family DUF1989 PF09347.10 KUM63945.1 - 1.7e-60 203.5 0.0 3e-60 202.7 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1989) Aminotran_1_2 PF00155.21 KUM63946.1 - 1.2e-19 70.8 0.0 1.5e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KUM63946.1 - 0.00041 19.3 0.0 0.00083 18.3 0.0 1.3 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Wax2_C PF12076.8 KUM63946.1 - 0.061 13.0 0.4 0.11 12.2 0.4 1.4 1 0 0 1 1 1 0 WAX2 C-terminal domain DegT_DnrJ_EryC1 PF01041.17 KUM63946.1 - 0.22 10.8 0.0 1.1 8.5 0.0 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.16 KUM63948.1 - 2.5e-24 85.9 27.3 2.5e-24 85.9 27.3 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM63948.1 - 1.9e-11 43.1 21.7 3.2e-11 42.4 21.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5509 PF17625.2 KUM63949.1 - 0.069 12.3 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5509) Dynactin PF12455.8 KUM63950.1 - 1.8e-87 293.2 12.4 1.8e-87 293.2 12.4 4.7 5 1 1 6 6 6 1 Dynein associated protein DUF2353 PF09789.9 KUM63950.1 - 0.0002 20.8 27.0 0.0002 20.8 27.0 4.2 4 1 1 5 5 5 2 Uncharacterized coiled-coil protein (DUF2353) Methyltransf_1N PF02870.15 KUM63950.1 - 0.13 13.1 1.0 4.4 8.2 0.0 3.1 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain FliO PF04347.13 KUM63951.1 - 0.0078 16.5 0.0 0.0093 16.2 0.0 1.1 1 0 0 1 1 1 1 Flagellar biosynthesis protein, FliO DUF3106 PF11304.8 KUM63951.1 - 0.057 13.9 0.0 0.067 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Solute_trans_a PF03619.16 KUM63952.1 - 3.4e-99 331.7 9.6 4.1e-99 331.4 9.6 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha UPF0182 PF03699.13 KUM63952.1 - 0.085 11.0 1.6 0.1 10.7 1.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) HAD_2 PF13419.6 KUM63954.1 - 1.8e-08 34.6 0.0 2.5e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KUM63954.1 - 4e-08 33.8 0.0 9.3e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KUM63954.1 - 0.022 14.8 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like RXT2_N PF08595.11 KUM63956.1 - 0.00029 20.9 7.2 0.00031 20.8 7.2 1.0 1 0 0 1 1 1 1 RXT2-like, N-terminal CDC45 PF02724.14 KUM63956.1 - 0.0029 16.0 10.6 0.0036 15.7 10.6 1.0 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 KUM63956.1 - 0.025 14.0 15.0 0.025 14.0 15.0 1.0 1 0 0 1 1 1 0 SDA1 Connexin PF00029.19 KUM63956.1 - 0.025 14.4 3.7 0.027 14.2 3.7 1.0 1 0 0 1 1 1 0 Connexin Prothymosin PF03247.14 KUM63956.1 - 0.028 14.9 30.0 0.034 14.6 30.0 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family FYDLN_acid PF09538.10 KUM63956.1 - 0.03 15.0 9.6 0.031 15.0 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) GEN1_C PF18380.1 KUM63956.1 - 0.04 14.8 8.1 0.05 14.5 8.1 1.2 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain RR_TM4-6 PF06459.12 KUM63956.1 - 0.059 13.2 11.3 0.061 13.2 11.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 KUM63956.1 - 0.081 12.6 11.1 0.11 12.2 11.1 1.2 1 0 0 1 1 1 0 FAM176 family DUF913 PF06025.12 KUM63956.1 - 0.1 11.6 4.7 0.094 11.7 4.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 KUM63956.1 - 0.16 10.1 16.9 0.17 10.0 16.9 1.0 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.11 KUM63956.1 - 0.17 11.9 17.1 0.19 11.7 17.1 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CPSF100_C PF13299.6 KUM63956.1 - 0.19 11.9 7.0 0.22 11.7 7.0 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Plasmodium_Vir PF05795.11 KUM63956.1 - 0.23 10.9 4.4 0.23 10.9 4.4 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4820 PF16091.5 KUM63956.1 - 0.24 10.7 7.7 0.27 10.6 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF2052 PF09747.9 KUM63956.1 - 0.26 11.4 18.7 0.33 11.1 18.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) TRAP_alpha PF03896.16 KUM63956.1 - 0.29 10.3 11.0 0.31 10.2 11.0 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_Rpc4 PF05132.14 KUM63956.1 - 0.33 11.4 6.9 0.36 11.2 6.9 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 KUM63956.1 - 0.33 9.7 5.9 0.35 9.6 5.9 1.0 1 0 0 1 1 1 0 Presenilin Sigma70_ner PF04546.13 KUM63956.1 - 0.4 10.5 15.2 0.47 10.3 15.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CLN3 PF02487.17 KUM63956.1 - 0.41 9.6 2.6 0.41 9.6 2.6 1.0 1 0 0 1 1 1 0 CLN3 protein Zip PF02535.22 KUM63956.1 - 0.46 9.6 3.6 0.48 9.6 3.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter RMI1_N PF08585.12 KUM63956.1 - 0.58 9.9 6.1 0.66 9.7 6.1 1.0 1 0 0 1 1 1 0 RecQ mediated genome instability protein YqfQ PF14181.6 KUM63956.1 - 0.6 10.3 12.1 0.7 10.1 12.1 1.0 1 0 0 1 1 1 0 YqfQ-like protein Tim54 PF11711.8 KUM63956.1 - 0.92 8.2 12.2 1 8.1 12.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SpoIIP PF07454.11 KUM63956.1 - 1.1 8.7 9.9 1.2 8.5 9.9 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TLP-20 PF06088.11 KUM63956.1 - 1.2 9.0 6.4 1.5 8.7 6.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) EIIBC-GUT_N PF03612.14 KUM63956.1 - 1.2 8.9 5.7 1.3 8.7 5.7 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4746 PF15928.5 KUM63956.1 - 1.2 8.4 18.5 1.4 8.3 18.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Afi1 PF07792.12 KUM63956.1 - 1.3 9.6 8.0 1.4 9.4 8.0 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Merozoite_SPAM PF07133.11 KUM63956.1 - 1.3 9.0 35.5 1.5 8.8 35.5 1.0 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Paf1 PF03985.13 KUM63956.1 - 1.3 7.9 21.3 1.5 7.7 21.3 1.0 1 0 0 1 1 1 0 Paf1 MCM_bind PF09739.9 KUM63956.1 - 1.4 7.3 7.4 1.4 7.2 7.4 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Cellulose_synt PF03552.14 KUM63956.1 - 1.4 7.3 3.1 1.5 7.2 3.1 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF5523 PF17661.1 KUM63956.1 - 1.4 8.5 18.7 1.7 8.3 18.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Serinc PF03348.15 KUM63956.1 - 1.7 7.5 3.0 1.6 7.6 3.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.6 KUM63956.1 - 1.8 6.9 3.5 1.8 6.9 3.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Pox_Ag35 PF03286.14 KUM63956.1 - 1.9 8.2 14.7 2.3 8.0 14.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Myc_N PF01056.18 KUM63956.1 - 2 8.2 11.5 2.4 8.0 11.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CobT PF06213.12 KUM63956.1 - 2 7.7 19.9 2.4 7.5 19.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT AIF_C PF14721.6 KUM63956.1 - 2.4 8.5 5.2 2.8 8.3 5.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term V_ATPase_I PF01496.19 KUM63956.1 - 2.6 5.8 6.6 2.9 5.7 6.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MAP17 PF15807.5 KUM63956.1 - 3 8.1 10.7 3.9 7.7 10.7 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RPN2_C PF18004.1 KUM63956.1 - 3.2 7.6 17.5 4.1 7.3 17.5 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Saw1 PF11561.8 KUM63956.1 - 3.3 7.2 6.2 3.5 7.1 6.2 1.1 1 0 0 1 1 1 0 Single strand annealing-weakened 1 ORC_WH_C PF18137.1 KUM63956.1 - 3.4 7.8 10.2 4.2 7.4 10.2 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DNA_pol_phi PF04931.13 KUM63956.1 - 3.4 5.7 23.3 3.9 5.5 23.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF3306 PF11748.8 KUM63956.1 - 4 8.3 15.4 4.8 8.1 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Fmp27 PF10344.9 KUM63956.1 - 4.2 5.3 8.8 4.5 5.2 8.8 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 TFIIF_alpha PF05793.12 KUM63956.1 - 4.2 5.8 21.6 4.6 5.7 21.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sec62 PF03839.16 KUM63956.1 - 4.3 6.8 5.9 4.8 6.6 5.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Nop53 PF07767.11 KUM63956.1 - 4.4 6.6 21.1 5.1 6.4 21.1 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CENP-T_N PF16171.5 KUM63956.1 - 4.7 6.0 9.2 5 5.9 9.2 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus DUF3464 PF11947.8 KUM63956.1 - 5.1 6.8 5.2 6 6.6 5.2 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RRN3 PF05327.11 KUM63956.1 - 5.2 5.5 10.6 5.2 5.5 10.6 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 KUM63956.1 - 5.3 6.3 16.7 6 6.1 16.7 1.0 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.13 KUM63956.1 - 6.8 5.4 8.3 7.8 5.2 8.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PTPRCAP PF15713.5 KUM63956.1 - 8 6.7 20.2 10 6.4 20.2 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RNA_polI_A34 PF08208.11 KUM63956.1 - 8.1 6.5 15.5 9.4 6.3 15.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 HSP90 PF00183.18 KUM63956.1 - 8.8 5.1 20.4 10 4.9 20.4 1.0 1 0 0 1 1 1 0 Hsp90 protein tRNA_bind_2 PF13725.6 KUM63956.1 - 8.8 5.9 11.9 9.6 5.8 11.9 1.0 1 0 0 1 1 1 0 Possible tRNA binding domain NOA36 PF06524.12 KUM63956.1 - 9.6 5.4 16.2 10 5.3 16.2 1.1 1 0 0 1 1 1 0 NOA36 protein TMEM119 PF15724.5 KUM63956.1 - 9.7 6.2 11.2 11 6.0 11.2 1.0 1 0 0 1 1 1 0 TMEM119 family RT_RNaseH PF17917.1 KUM63957.1 - 3.7e-12 46.5 0.5 5.5e-12 45.9 0.5 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KUM63957.1 - 3.2e-07 30.3 0.2 7.8e-07 29.1 0.1 1.7 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 KUM63957.1 - 0.00042 20.1 0.1 0.00055 19.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like Phenyl_P_gamma PF09662.10 KUM63957.1 - 0.031 14.4 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) MISS PF15822.5 KUM63960.1 - 0.013 15.4 9.6 0.013 15.4 9.6 1.7 1 1 1 2 2 2 0 MAPK-interacting and spindle-stabilising protein-like Choline_transpo PF04515.12 KUM63961.1 - 2.2e-81 273.6 25.6 2.2e-81 273.6 25.6 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Defensin_big PF14862.6 KUM63961.1 - 0.099 13.0 1.3 19 5.6 0.0 3.4 3 0 0 3 3 3 0 Big defensin DUF4229 PF14012.6 KUM63961.1 - 0.12 12.5 0.2 0.12 12.5 0.2 4.8 6 1 1 7 7 7 0 Protein of unknown function (DUF4229) Pex14_N PF04695.13 KUM63961.1 - 0.53 10.9 5.3 1.2 9.7 5.3 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NAD_binding_10 PF13460.6 KUM63962.1 - 1.2e-13 51.3 0.6 1.8e-13 50.8 0.6 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KUM63962.1 - 2.6e-12 46.8 0.0 3.5e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KUM63962.1 - 4.6e-07 30.2 0.1 7e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KUM63962.1 - 5.6e-05 22.7 0.4 9e-05 22.0 0.4 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KUM63962.1 - 0.00048 20.5 0.1 0.001 19.5 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KUM63962.1 - 0.0035 17.3 0.3 0.0052 16.7 0.3 1.3 1 0 0 1 1 1 1 KR domain GFO_IDH_MocA PF01408.22 KUM63962.1 - 0.0077 17.0 0.1 0.015 16.1 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 KUM63962.1 - 0.0092 16.1 0.1 0.021 14.9 0.1 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.23 KUM63962.1 - 0.088 12.9 0.6 0.2 11.8 0.6 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KUM63962.1 - 0.1 13.2 0.2 0.2 12.3 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AA_permease PF00324.21 KUM63963.1 - 3.9e-105 352.2 51.0 4.7e-105 351.9 51.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM63963.1 - 1.1e-28 100.2 52.5 1.6e-28 99.7 52.5 1.2 1 0 0 1 1 1 1 Amino acid permease GMC_oxred_N PF00732.19 KUM63964.1 - 4.1e-27 95.3 0.0 3.3e-26 92.3 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM63964.1 - 4.9e-25 88.7 0.0 7.9e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DUF2713 PF10897.8 KUM63965.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) DUF5122 PF17164.4 KUM63965.1 - 0.13 12.6 0.1 0.31 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller Glyco_hydro_16 PF00722.21 KUM63966.1 - 9.2e-41 139.2 3.9 9.2e-41 139.2 3.9 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 MFS_1 PF07690.16 KUM63967.1 - 1e-37 129.9 14.6 1e-37 129.9 14.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM63967.1 - 4.3e-08 32.5 8.3 4.3e-08 32.5 8.3 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter YfhO PF09586.10 KUM63967.1 - 0.1 10.8 0.2 0.19 10.0 0.2 1.4 1 0 0 1 1 1 0 Bacterial membrane protein YfhO OATP PF03137.20 KUM63967.1 - 0.21 9.9 9.4 0.028 12.7 2.5 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4231 PF14015.6 KUM63967.1 - 1.1 9.7 8.8 6.2 7.4 0.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) PhaG_MnhG_YufB PF03334.14 KUM63967.1 - 1.4 9.2 8.4 20 5.5 0.0 4.2 4 0 0 4 4 4 0 Na+/H+ antiporter subunit HATPase_c PF02518.26 KUM63968.1 - 2.7e-25 89.1 0.1 7e-25 87.7 0.1 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KUM63968.1 - 6.1e-20 71.5 0.4 1.1e-19 70.6 0.4 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KUM63968.1 - 9.6e-13 48.0 0.0 2.6e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 KUM63968.1 - 0.099 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 GHKL domain Adaptin_N PF01602.20 KUM63969.1 - 1.5e-91 307.6 12.5 2.5e-91 306.8 12.5 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KUM63969.1 - 2.9e-58 195.7 0.5 6.8e-58 194.5 0.5 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KUM63969.1 - 2.8e-56 189.0 0.0 9.2e-56 187.3 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KUM63969.1 - 8.7e-12 45.4 6.6 6.9e-10 39.2 0.1 3.4 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KUM63969.1 - 2.1e-09 37.6 11.5 5.6e-05 23.5 0.0 5.6 3 1 3 6 6 6 3 HEAT repeats Coatomer_g_Cpla PF16381.5 KUM63969.1 - 8.9e-05 22.6 0.0 0.00062 19.9 0.0 2.5 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 KUM63969.1 - 0.00021 21.3 0.6 1.1 9.8 0.1 4.8 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KUM63969.1 - 0.0029 18.1 0.4 0.23 12.0 0.0 4.3 4 1 1 5 5 5 2 HEAT-like repeat AP4E_app_platf PF14807.6 KUM63969.1 - 0.0044 17.3 0.2 0.016 15.5 0.2 2.1 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform RTP1_C1 PF10363.9 KUM63969.1 - 0.028 14.6 3.6 4.6 7.5 0.3 3.9 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KUM63969.1 - 6.7 6.9 9.3 2.2 8.5 0.0 4.7 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DAGK_cat PF00781.24 KUM63970.1 - 3.1e-23 81.8 0.0 5.3e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain CRAL_TRIO PF00650.20 KUM63971.1 - 2.5e-22 79.3 0.0 3.9e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KUM63971.1 - 0.00074 19.7 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Thioesterase PF00975.20 KUM63975.1 - 1e-26 94.5 0.0 1.8e-26 93.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KUM63975.1 - 2.4e-09 37.4 0.3 4.9e-09 36.4 0.3 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Acetyltransf_10 PF13673.7 KUM63976.1 - 2.8e-10 40.2 0.0 3.7e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM63976.1 - 6.7e-09 36.0 0.0 9.2e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KUM63976.1 - 6e-07 29.8 0.0 8.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KUM63976.1 - 0.0015 18.7 0.0 0.0018 18.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CesT PF05932.13 KUM63976.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family NAD_binding_10 PF13460.6 KUM63977.1 - 5.1e-07 29.7 0.0 7.3e-07 29.2 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KUM63977.1 - 1.2e-06 28.2 0.0 8.5e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KUM63977.1 - 2.5e-05 24.0 0.5 8.6e-05 22.2 0.1 2.0 1 1 0 2 2 2 1 NmrA-like family HIM1 PF08732.10 KUM63977.1 - 0.00011 21.8 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 HIM1 Semialdhyde_dh PF01118.24 KUM63977.1 - 0.027 14.9 0.0 0.049 14.1 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KUM63977.1 - 0.075 13.1 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 KUM63977.1 - 0.1 11.6 0.0 1.8 7.5 0.0 2.4 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family CAP18_C PF12153.8 KUM63977.1 - 0.11 12.3 0.4 0.21 11.5 0.4 1.4 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) Glyco_transf_90 PF05686.12 KUM63978.1 - 1e-14 54.3 1.3 4.3e-08 32.5 0.0 3.1 3 0 0 3 3 3 3 Glycosyl transferase family 90 HATPase_c PF02518.26 KUM63979.1 - 7.5e-20 71.5 0.5 1.8e-19 70.3 0.5 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KUM63979.1 - 6.5e-19 68.2 0.1 2.2e-18 66.4 0.2 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KUM63979.1 - 2.3e-10 40.4 0.1 6.8e-10 38.8 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KUM63979.1 - 0.012 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RabGAP-TBC PF00566.18 KUM63980.1 - 1.8e-37 129.1 0.0 2.5e-36 125.3 0.0 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Peptidase_M64 PF09471.10 KUM63980.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 IgA Peptidase M64 DUF1604 PF07713.13 KUM63981.1 - 2.6e-39 132.9 1.6 2.6e-39 132.9 1.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KUM63981.1 - 1.1e-06 28.5 3.7 1.7e-06 27.8 2.2 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KUM63981.1 - 0.019 15.0 0.7 0.019 15.0 0.7 3.2 3 1 0 3 3 3 0 G-patch domain DUF3431 PF11913.8 KUM63982.1 - 1.2e-57 195.2 0.0 1.3e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DNA_ligase_ZBD PF03119.16 KUM63982.1 - 0.063 13.3 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Amino_oxidase PF01593.24 KUM63984.1 - 3.7e-36 125.4 0.0 4.5e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Acetyltransf_3 PF13302.7 KUM63985.1 - 2.5e-34 118.9 0.0 2.9e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM63985.1 - 4.8e-07 30.0 0.0 7.8e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KUM63985.1 - 0.03 14.8 0.0 0.053 13.9 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KUM63985.1 - 0.091 12.9 0.0 7.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_transf_90 PF05686.12 KUM63986.1 - 1.4e-13 50.5 7.8 5e-08 32.3 5.1 4.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 UBD PF16455.5 KUM63988.1 - 2.6e-42 143.3 0.0 3.8e-42 142.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-binding domain DUF4050 PF13259.6 KUM63988.1 - 0.016 15.6 2.1 0.019 15.3 2.1 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) Nop52 PF05997.12 KUM63989.1 - 6.2e-53 179.8 0.4 8.5e-52 176.1 0.4 2.0 1 1 0 1 1 1 1 Nucleolar protein,Nop52 NOT2_3_5 PF04153.18 KUM63989.1 - 0.04 14.0 0.1 0.079 13.0 0.1 1.5 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family HEAT PF02985.22 KUM63989.1 - 0.054 13.8 0.0 1.7 9.2 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat PGA2 PF07543.12 KUM63989.1 - 0.067 13.2 6.5 0.041 13.9 2.3 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 PPL5 PF18168.1 KUM63989.1 - 0.13 11.5 0.2 0.2 10.9 0.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 RXT2_N PF08595.11 KUM63989.1 - 7.4 6.6 8.3 0.29 11.1 0.5 2.3 3 0 0 3 3 3 0 RXT2-like, N-terminal Vac_ImportDeg PF09783.9 KUM63990.1 - 4.7e-69 231.3 1.2 5.6e-69 231.1 1.2 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.14 KUM63991.1 - 4.2e-73 244.1 0.3 5e-73 243.9 0.3 1.1 1 0 0 1 1 1 1 Mago nashi protein Transp_cyt_pur PF02133.15 KUM63992.1 - 1.3e-18 67.1 42.4 2.8e-18 66.0 42.4 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Tubulin PF00091.25 KUM63994.1 - 6.2e-68 228.9 0.0 1.4e-67 227.7 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KUM63994.1 - 1.4e-43 148.0 0.0 2.8e-43 147.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KUM63994.1 - 2.3e-05 24.7 0.0 6.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KUM63994.1 - 0.0012 18.2 0.1 0.026 13.7 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KUM63994.1 - 0.0028 17.4 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.22 KUM63995.1 - 3.5e-15 55.6 0.0 6.7e-06 25.8 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ammonium_transp PF00909.21 KUM63997.1 - 1.8e-123 412.2 31.1 2.1e-123 412.0 31.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF441 PF04284.13 KUM63997.1 - 0.081 12.9 3.2 0.19 11.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF441) RRM_1 PF00076.22 KUM63998.1 - 2.3e-12 46.5 0.0 3.3e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spem1 PF15670.5 KUM63998.1 - 0.97 9.0 9.0 1.2 8.6 9.0 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 Pkinase PF00069.25 KUM63999.1 - 4.5e-66 222.9 0.0 7.1e-66 222.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM63999.1 - 3.2e-36 124.9 0.0 1.9e-33 115.9 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM63999.1 - 0.00069 19.0 0.3 0.013 14.8 0.3 2.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KUM63999.1 - 0.0026 17.7 0.0 0.0067 16.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KUM63999.1 - 0.0056 15.5 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KUM63999.1 - 0.0098 15.0 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 FtsX_ECD PF18075.1 KUM63999.1 - 0.053 14.2 0.0 0.22 12.2 0.0 2.1 2 0 0 2 2 2 0 FtsX extracellular domain FERM_f0 PF16511.5 KUM63999.1 - 0.081 13.2 0.1 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM YrbL-PhoP_reg PF10707.9 KUM63999.1 - 0.15 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Phe_hydrox_dim PF07976.12 KUM64000.1 - 1.6e-22 80.3 0.0 2.3e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Slp PF03843.13 KUM64000.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family EI24 PF07264.11 KUM64001.1 - 1.3e-11 45.1 0.5 2e-11 44.4 0.5 1.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) LRR_8 PF13855.6 KUM64002.1 - 3.9e-14 52.1 10.4 1.1e-08 34.6 1.2 3.9 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KUM64002.1 - 5.4e-14 52.1 3.3 0.0013 19.1 0.0 4.5 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KUM64002.1 - 0.00068 19.2 0.2 0.018 14.6 0.2 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KUM64002.1 - 0.0058 17.0 8.8 18 6.4 0.1 6.3 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 KUM64002.1 - 0.034 14.2 11.8 0.93 9.7 0.5 5.0 5 0 0 5 5 5 0 Leucine Rich repeat AflR PF08493.10 KUM64003.1 - 8.8e-05 22.1 0.6 0.00012 21.6 0.6 1.2 1 0 0 1 1 1 1 Aflatoxin regulatory protein Nuc_sug_transp PF04142.15 KUM64005.1 - 3.8e-31 108.4 12.3 5e-31 108.0 12.3 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KUM64005.1 - 2.4e-06 27.0 8.1 3.1e-06 26.6 7.7 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KUM64005.1 - 6.6e-05 23.1 27.5 0.0082 16.3 13.0 2.9 3 0 0 3 3 3 2 EamA-like transporter family TMEM234 PF10639.9 KUM64005.1 - 0.084 12.9 4.9 0.058 13.4 1.0 2.3 2 0 0 2 2 2 0 Putative transmembrane family 234 IQ PF00612.27 KUM64006.1 - 0.012 15.3 0.4 0.012 15.3 0.4 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif Senescence PF06911.12 KUM64008.1 - 0.03 14.6 5.7 0.049 13.9 5.7 1.3 1 1 0 1 1 1 0 Senescence-associated protein VPS13_C PF16909.5 KUM64008.1 - 0.088 12.6 1.4 0.14 11.9 1.4 1.4 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Lactamase_B PF00753.27 KUM64009.1 - 5.3e-18 65.7 5.3 4.6e-17 62.7 5.3 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KUM64009.1 - 5.2e-06 26.1 1.2 8.8e-06 25.4 1.2 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KUM64009.1 - 0.00019 20.9 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KUM64009.1 - 0.0047 16.8 0.6 0.017 15.0 0.6 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 KUM64009.1 - 0.025 14.6 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain PaaX PF07848.12 KUM64009.1 - 0.17 12.1 0.0 5.4 7.3 0.0 2.8 3 0 0 3 3 3 0 PaaX-like protein CAP59_mtransfer PF11735.8 KUM64011.1 - 1.1e-73 247.9 0.0 1.4e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 SPC12 PF06645.13 KUM64011.1 - 0.13 12.4 0.6 0.23 11.5 0.6 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) PIG-L PF02585.17 KUM64012.1 - 5.1e-16 59.5 0.2 3.2e-15 56.9 0.2 2.0 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase Aminotran_4 PF01063.19 KUM64013.1 - 5.2e-33 114.8 0.0 6.5e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Arf PF00025.21 KUM64014.1 - 4.4e-65 218.4 0.0 4.9e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KUM64014.1 - 9.6e-11 41.4 0.0 3.2e-07 29.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KUM64014.1 - 2.9e-08 33.4 0.0 3.8e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KUM64014.1 - 5e-07 30.0 0.0 1.2e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KUM64014.1 - 5.9e-07 29.6 0.0 7.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KUM64014.1 - 1.9e-05 24.3 0.0 2.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KUM64014.1 - 0.00011 21.7 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 KUM64014.1 - 0.062 12.9 0.0 4.6 6.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 KUM64014.1 - 0.07 12.7 0.0 2.3 7.7 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DUF2457 PF10446.9 KUM64015.1 - 6.9e-141 470.6 34.8 6.9e-141 470.6 34.8 3.7 2 2 0 3 3 3 1 Protein of unknown function (DUF2457) Metallophos PF00149.28 KUM64017.1 - 3.5e-40 138.7 0.1 4.5e-40 138.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KUM64017.1 - 1e-22 80.3 2.7 1.3e-22 79.9 1.8 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Fungal_trans PF04082.18 KUM64018.1 - 1.5e-13 50.4 0.4 2.4e-13 49.7 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Jacalin PF01419.17 KUM64019.1 - 0.00095 19.1 1.8 0.0014 18.5 1.7 1.4 1 1 0 1 1 1 1 Jacalin-like lectin domain MFS_1 PF07690.16 KUM64020.1 - 6.9e-31 107.4 31.8 6.9e-31 107.4 31.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KUM64020.1 - 0.00032 20.1 3.5 0.00032 20.1 3.5 2.9 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Lactonase PF10282.9 KUM64021.1 - 7.4e-86 288.5 0.0 9.4e-86 288.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NinG PF05766.12 KUM64022.1 - 0.0075 16.2 0.2 0.015 15.3 0.1 1.5 1 1 1 2 2 2 1 Bacteriophage Lambda NinG protein HTH_10 PF04967.12 KUM64022.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain Ribosomal_60s PF00428.19 KUM64022.1 - 0.33 11.6 7.2 0.21 12.2 5.3 1.7 1 1 0 1 1 1 0 60s Acidic ribosomal protein Glyco_hydro_76 PF03663.14 KUM64023.1 - 4.6e-137 457.4 17.9 5.3e-137 457.2 17.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cloacin_immun PF03513.14 KUM64023.1 - 0.012 15.9 0.1 0.026 14.9 0.1 1.6 1 0 0 1 1 1 0 Cloacin immunity protein Aldo_ket_red PF00248.21 KUM64025.1 - 5.9e-39 134.0 0.0 9e-39 133.4 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family TEA PF01285.18 KUM64026.1 - 2.1e-27 95.0 0.0 4.1e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain RRM_1 PF00076.22 KUM64027.1 - 2e-66 219.7 3.6 1.5e-18 66.4 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KUM64027.1 - 9.2e-09 35.0 0.0 0.061 12.9 0.0 4.8 4 1 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KUM64027.1 - 4.8e-06 26.3 0.0 0.047 13.6 0.0 3.3 4 0 0 4 4 4 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KUM64027.1 - 0.0001 22.3 0.3 2.4 8.3 0.0 5.1 5 0 0 5 5 5 1 Limkain b1 Nup35_RRM_2 PF14605.6 KUM64027.1 - 0.002 18.1 0.1 2.4 8.2 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KUM64027.1 - 0.024 14.7 0.0 12 6.1 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif Arm-DNA-bind_4 PF14657.6 KUM64027.1 - 0.11 12.2 1.8 11 5.9 0.0 3.3 3 0 0 3 3 3 0 Arm DNA-binding domain TraH_2 PF06871.11 KUM64027.1 - 0.13 11.9 1.3 1.5 8.4 0.0 2.8 2 0 0 2 2 2 0 TraH_2 Dynein_light PF01221.18 KUM64028.1 - 6.3e-38 129.0 1.5 8.3e-38 128.6 1.5 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 zinc_ribbon_15 PF17032.5 KUM64029.1 - 0.0053 17.5 1.4 0.0095 16.7 1.4 1.4 1 0 0 1 1 1 1 zinc-ribbon family p450 PF00067.22 KUM64030.1 - 2.8e-48 164.8 0.0 4.4e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 OPT PF03169.15 KUM64030.1 - 0.25 9.9 0.1 0.32 9.6 0.1 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein HRI1 PF16815.5 KUM64032.1 - 6.9e-29 101.2 0.7 1.9e-28 99.7 0.7 1.6 1 1 0 1 1 1 1 Protein HRI1 Vezatin PF12632.7 KUM64034.1 - 4.3e-67 226.4 0.1 9e-67 225.4 0.0 1.5 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes PCNA_N PF00705.18 KUM64035.1 - 8.5e-56 187.1 2.5 2.1e-55 185.9 2.5 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KUM64035.1 - 3.8e-51 172.6 0.0 8.1e-51 171.5 0.0 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KUM64035.1 - 4.1e-07 29.7 0.1 6.2e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KUM64035.1 - 2.5e-05 23.5 0.4 0.00086 18.5 0.4 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 KUM64035.1 - 0.0011 18.2 0.3 0.0081 15.3 0.1 2.1 2 0 0 2 2 2 1 Hus1-like protein Gly_transf_sug PF04488.15 KUM64036.1 - 2.9e-06 27.8 0.0 5.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Phage_holin_2_4 PF16082.5 KUM64037.1 - 0.12 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Sec61_beta PF03911.16 KUM64038.1 - 2.9e-17 62.4 0.8 4.5e-17 61.8 0.8 1.3 1 0 0 1 1 1 1 Sec61beta family SSF PF00474.17 KUM64039.1 - 3.1e-20 72.4 30.7 5e-20 71.7 30.7 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family NMT_C PF02799.15 KUM64040.1 - 1.8e-75 253.1 0.0 2.6e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KUM64040.1 - 3.1e-70 235.2 0.0 1.2e-69 233.2 0.0 1.9 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 KUM64040.1 - 1.3e-05 25.4 0.0 2.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KUM64040.1 - 0.009 16.1 0.0 0.041 14.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Luciferase_N PF05295.11 KUM64040.1 - 0.15 12.1 0.2 0.49 10.4 0.1 1.9 2 0 0 2 2 2 0 Luciferase/LBP N-terminal domain DUF2491 PF10679.9 KUM64040.1 - 0.18 11.0 0.4 12 5.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2491) Abhydrolase_6 PF12697.7 KUM64041.1 - 1.2e-06 29.4 0.8 1.8e-06 28.7 0.8 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KUM64041.1 - 0.00093 18.2 0.0 0.0016 17.4 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase Amino_oxidase PF01593.24 KUM64042.1 - 4.5e-51 174.5 0.4 2.4e-50 172.1 0.4 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KUM64042.1 - 7.4e-16 58.1 0.5 2.7e-15 56.3 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM64042.1 - 7.2e-06 25.4 0.6 3.8e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM64042.1 - 9.3e-05 22.9 0.3 0.0002 21.8 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM64042.1 - 0.00016 21.7 1.4 0.23 11.5 0.4 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 KUM64042.1 - 0.00035 19.4 1.5 0.00073 18.3 0.3 1.9 2 0 0 2 2 2 1 HI0933-like protein Prenylcys_lyase PF07156.14 KUM64042.1 - 0.00045 19.4 0.2 0.00062 19.0 0.2 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase FAD_binding_2 PF00890.24 KUM64042.1 - 0.00082 18.6 0.2 0.0014 17.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KUM64042.1 - 0.0017 18.0 9.6 0.0017 18.0 6.3 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KUM64042.1 - 0.0019 17.6 0.0 0.004 16.6 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KUM64042.1 - 0.0098 15.2 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KUM64042.1 - 0.012 14.8 0.2 0.021 14.1 0.2 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KUM64042.1 - 0.032 13.5 0.3 0.067 12.4 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KUM64042.1 - 0.045 13.6 0.4 0.092 12.6 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KUM64042.1 - 0.28 10.2 2.6 0.19 10.8 0.6 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.16 KUM64042.1 - 0.46 10.1 1.8 20 4.8 0.1 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.16 KUM64045.1 - 5.3e-28 97.9 62.4 2e-27 96.1 34.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM64046.1 - 9.8e-11 41.2 5.3 9.8e-11 41.2 5.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter NAD_binding_10 PF13460.6 KUM64047.1 - 3.9e-08 33.4 0.0 6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KUM64047.1 - 1.9e-07 30.9 0.1 2.4e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.6 KUM64047.1 - 0.0035 16.9 0.2 0.0061 16.1 0.2 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KUM64047.1 - 0.011 15.2 0.0 0.38 10.2 0.0 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KUM64047.1 - 0.012 15.1 0.2 0.022 14.2 0.1 1.4 1 1 0 1 1 1 0 short chain dehydrogenase Fungal_trans PF04082.18 KUM64048.1 - 1.9e-09 36.9 0.0 3.5e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Homeodomain PF00046.29 KUM64049.1 - 4.1e-15 55.4 2.7 1.1e-14 54.0 2.7 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KUM64049.1 - 0.049 13.6 0.2 0.15 12.0 0.2 1.8 1 0 0 1 1 1 0 Homeobox KN domain BCIP PF13862.6 KUM64050.1 - 0.05 13.4 0.5 0.1 12.4 0.5 1.5 1 0 0 1 1 1 0 p21-C-terminal region-binding protein Lys-AminoMut_A PF09043.11 KUM64052.1 - 0.0026 16.3 0.0 0.0037 15.8 0.0 1.1 1 0 0 1 1 1 1 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit Aldo_ket_red PF00248.21 KUM64053.1 - 4e-46 157.5 0.0 6.9e-46 156.8 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family PHD PF00628.29 KUM64054.1 - 2.4e-10 40.1 7.2 2.4e-10 40.1 7.2 2.6 2 0 0 2 2 2 1 PHD-finger APH PF01636.23 KUM64054.1 - 0.12 12.3 0.2 0.77 9.6 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family Sigma70_r2 PF04542.14 KUM64055.1 - 0.043 13.6 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-70 region 2 ADH_N PF08240.12 KUM64056.1 - 1.2e-25 89.5 4.5 2e-25 88.8 4.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM64056.1 - 9.3e-16 58.0 0.0 2.1e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KUM64056.1 - 0.00028 20.3 0.1 0.00049 19.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KUM64057.1 - 2.6e-27 95.5 0.0 4.6e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM64057.1 - 1.1e-10 41.4 12.9 2e-10 40.6 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KUM64057.1 - 0.14 12.3 2.1 0.17 12.1 0.1 2.1 2 0 0 2 2 2 0 Gal4-like dimerisation domain DUF4446 PF14584.6 KUM64057.1 - 0.22 11.5 0.0 0.46 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) 2OG-FeII_Oxy_3 PF13640.6 KUM64058.1 - 4.1e-13 50.0 0.1 6.5e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.24 KUM64059.1 - 1.9e-101 340.2 27.2 2.1e-101 340.0 27.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM64059.1 - 1.1e-27 97.0 40.1 1.8e-23 83.1 21.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.12 KUM64059.1 - 0.089 13.0 0.4 0.31 11.2 0.4 1.9 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF3899 PF13038.6 KUM64059.1 - 0.2 12.2 2.3 0.93 10.0 2.3 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Phage_holin_3_2 PF04550.12 KUM64059.1 - 1.7 9.2 6.1 2.5 8.7 2.4 2.8 3 0 0 3 3 3 0 Phage holin family 2 Abhydrolase_6 PF12697.7 KUM64060.1 - 1.3e-23 84.8 0.2 1.4e-23 84.6 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM64060.1 - 0.00012 21.4 0.1 0.0012 18.2 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 KUM64060.1 - 0.064 12.8 0.0 2.6 7.5 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family Lys-AminoMut_A PF09043.11 KUM64060.1 - 0.1 11.0 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit Abhydrolase_1 PF00561.20 KUM64060.1 - 0.16 11.6 0.0 0.38 10.4 0.0 1.5 1 1 1 2 2 2 0 alpha/beta hydrolase fold AMP-binding PF00501.28 KUM64061.1 - 1e-75 254.9 0.0 1.8e-75 254.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KUM64061.1 - 3.1e-60 203.5 0.0 6.7e-60 202.4 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KUM64061.1 - 3.1e-51 173.6 2.6 5.9e-51 172.7 2.6 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM64061.1 - 8.4e-38 130.2 1.5 1.6e-37 129.3 1.5 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM64061.1 - 3.5e-18 66.2 2.8 6.6e-15 55.5 2.1 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KUM64061.1 - 1e-16 61.1 0.0 1.2e-08 34.8 0.0 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KUM64061.1 - 1.6e-12 47.6 0.0 3.4e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KUM64061.1 - 3.9e-08 32.6 0.0 0.001 18.1 0.0 3.2 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KUM64061.1 - 1.1e-06 28.0 0.7 0.00011 21.4 0.0 2.6 3 0 0 3 3 3 1 RmlD substrate binding domain AMP-binding_C PF13193.6 KUM64061.1 - 0.0068 17.4 0.2 0.05 14.6 0.0 2.7 3 0 0 3 3 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 KUM64061.1 - 0.013 14.7 0.8 6.9 5.7 0.2 3.2 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein ApbA PF02558.16 KUM64061.1 - 0.018 14.7 0.1 0.042 13.5 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDP_Man_Dehyd PF16363.5 KUM64061.1 - 0.029 13.8 0.0 3 7.1 0.0 2.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DFP PF04127.15 KUM64061.1 - 0.13 12.1 2.4 0.39 10.5 1.6 2.2 3 0 0 3 3 3 0 DNA / pantothenate metabolism flavoprotein Fungal_trans_2 PF11951.8 KUM64063.1 - 3.3e-39 134.8 1.9 3.9e-39 134.5 1.9 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Arf PF00025.21 KUM64064.1 - 5.4e-71 237.6 0.1 6.3e-71 237.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KUM64064.1 - 3.5e-16 59.5 0.1 4.8e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KUM64064.1 - 2.7e-13 49.8 0.0 2.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KUM64064.1 - 7e-13 48.4 1.3 1.2e-08 34.6 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KUM64064.1 - 1.9e-11 43.7 0.0 2.4e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KUM64064.1 - 4.5e-10 39.3 0.0 5.2e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KUM64064.1 - 7e-06 26.1 0.1 1.6e-05 25.0 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KUM64064.1 - 0.0021 17.6 0.0 0.0035 16.9 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KUM64064.1 - 0.0093 15.5 0.3 0.018 14.6 0.2 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B 6PF2K PF01591.18 KUM64064.1 - 0.017 14.4 0.3 0.03 13.6 0.3 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Glycos_transf_1 PF00534.20 KUM64065.1 - 2.9e-17 62.8 0.0 5.6e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KUM64065.1 - 5.7e-13 49.5 0.0 9.3e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KUM64065.1 - 5.3e-05 23.5 0.0 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Meth_synt_2 PF01717.18 KUM64066.1 - 1.8e-10 40.6 0.0 1.5e-06 27.7 0.0 2.6 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KUM64066.1 - 0.028 13.9 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain DUF2235 PF09994.9 KUM64069.1 - 3.2e-102 341.8 0.1 4.2e-102 341.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF896 PF05979.12 KUM64069.1 - 0.37 10.7 1.6 0.44 10.5 0.1 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Hexapep PF00132.24 KUM64070.1 - 6.1e-06 25.8 9.4 0.011 15.4 4.1 4.9 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KUM64070.1 - 0.0088 15.8 0.4 0.0088 15.8 0.4 2.6 3 1 1 4 4 4 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KUM64070.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase An_peroxidase PF03098.15 KUM64071.1 - 5.4e-36 124.3 0.0 3.7e-19 68.7 0.0 3.3 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 KUM64071.1 - 1.8e-06 27.0 0.0 7.3e-05 21.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 B12-binding_2 PF02607.17 KUM64071.1 - 0.035 14.5 0.0 0.1 13.1 0.0 1.9 1 0 0 1 1 1 0 B12 binding domain PilP PF04351.13 KUM64071.1 - 0.069 13.1 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Pilus assembly protein, PilP Zip PF02535.22 KUM64072.1 - 1.9 7.6 3.6 2.5 7.2 3.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 KUM64072.1 - 4.4 6.0 7.1 6.1 5.5 7.1 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 KUM64072.1 - 5.4 5.2 15.4 7.1 4.8 15.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DHDPS PF00701.22 KUM64073.1 - 3e-33 114.8 0.0 2.5e-26 92.1 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.22 KUM64074.1 - 5.2e-10 40.2 0.1 1.4e-09 38.8 0.1 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF5466 PF17554.2 KUM64075.1 - 0.075 13.2 3.9 0.15 12.3 3.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5466) ING PF12998.7 KUM64076.1 - 9.1e-06 26.2 0.0 2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KUM64076.1 - 1.2e-05 25.1 10.2 1.2e-05 25.1 10.2 1.6 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 KUM64076.1 - 0.022 15.0 2.2 0.046 14.0 2.2 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain PH_14 PF17787.1 KUM64076.1 - 0.1 12.5 0.2 0.1 12.5 0.2 1.9 2 0 0 2 2 2 0 PH domain zf-HC5HC2H_2 PF13832.6 KUM64076.1 - 0.12 12.5 2.1 0.21 11.7 2.1 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain BrnA_antitoxin PF14384.6 KUM64076.1 - 0.59 10.7 3.5 13 6.4 0.1 3.5 3 0 0 3 3 3 0 BrnA antitoxin of type II toxin-antitoxin system Chal_sti_synt_C PF02797.15 KUM64077.1 - 6.6e-19 68.4 0.0 1.2e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 KUM64077.1 - 5.4e-13 48.9 0.1 8.5e-13 48.2 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III_C PF08541.10 KUM64077.1 - 1.5e-08 34.7 0.0 1.2e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.12 KUM64077.1 - 0.019 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein Thiolase_N PF00108.23 KUM64077.1 - 0.13 11.6 1.2 0.2 11.0 0.1 1.8 2 0 0 2 2 2 0 Thiolase, N-terminal domain Ribosomal_60s PF00428.19 KUM64078.1 - 2.4 8.8 4.9 1.1 9.9 2.1 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein TENA_THI-4 PF03070.16 KUM64079.1 - 1.5e-11 44.6 0.0 7.7e-06 25.9 0.0 2.7 3 0 0 3 3 3 2 TENA/THI-4/PQQC family Forkhead PF00250.18 KUM64080.1 - 2.3e-35 120.7 1.0 4.1e-35 119.9 1.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KUM64080.1 - 6.4e-08 32.8 0.0 1.7e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 FHA domain zf-C2H2 PF00096.26 KUM64081.1 - 2.8e-07 30.6 15.4 3.4e-05 24.0 2.8 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KUM64081.1 - 9.1e-06 25.9 5.7 2.7e-05 24.4 3.3 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KUM64081.1 - 0.00011 22.7 1.7 0.00011 22.7 1.7 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KUM64081.1 - 0.00086 19.6 2.8 0.002 18.4 2.8 1.7 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KUM64081.1 - 0.0032 17.7 1.9 0.0039 17.4 0.7 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KUM64081.1 - 0.004 17.1 1.3 0.0084 16.1 1.3 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-TRAF PF02176.18 KUM64081.1 - 0.11 13.2 5.0 0.37 11.5 2.4 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger FOXP-CC PF16159.5 KUM64081.1 - 0.48 11.1 7.4 2.1 9.0 0.5 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-Di19 PF05605.12 KUM64081.1 - 7 7.0 7.9 14 6.1 0.5 2.4 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KUM64081.1 - 7.2 7.0 6.4 4.1 7.8 3.1 2.2 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) La PF05383.17 KUM64082.1 - 2.4e-19 69.2 0.5 4.1e-19 68.4 0.5 1.3 1 0 0 1 1 1 1 La domain NPR3 PF03666.13 KUM64083.1 - 1.2e-153 512.3 0.0 1.2e-153 512.3 0.0 2.7 3 0 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 Mago-bind PF09282.10 KUM64083.1 - 0.049 13.5 2.1 0.2 11.6 2.1 2.0 1 0 0 1 1 1 0 Mago binding NPR2 PF06218.11 KUM64083.1 - 0.1 11.3 0.0 0.36 9.5 0.0 1.8 2 0 0 2 2 2 0 Nitrogen permease regulator 2 FAM176 PF14851.6 KUM64083.1 - 2.1 8.0 9.0 5.2 6.7 0.9 3.1 3 0 0 3 3 3 0 FAM176 family Band_7 PF01145.25 KUM64084.1 - 6.6e-31 107.7 1.0 1.3e-30 106.7 1.0 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KUM64084.1 - 1.8e-22 79.1 0.4 4.7e-22 77.8 0.4 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 KUM64084.1 - 0.033 13.5 0.2 0.049 12.9 0.2 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein Band_7_1 PF13421.6 KUM64084.1 - 0.053 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family YchF-GTPase_C PF06071.13 KUM64088.1 - 9.1e-35 118.7 0.2 2e-34 117.6 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KUM64088.1 - 2.1e-16 60.0 0.0 6.9e-16 58.4 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KUM64088.1 - 0.00074 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KUM64088.1 - 0.0052 16.8 0.0 0.015 15.4 0.0 1.7 2 0 0 2 2 2 1 TGS domain AAA_14 PF13173.6 KUM64088.1 - 0.094 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hira PF07569.11 KUM64089.1 - 3.7e-84 281.9 0.0 6.8e-84 281.0 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KUM64089.1 - 1.4e-27 95.4 22.7 7e-05 23.5 0.0 8.9 7 1 1 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM64089.1 - 1.5e-14 54.0 0.0 0.019 15.3 0.0 6.1 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KUM64089.1 - 2.4e-09 36.8 0.0 8.1e-09 35.1 0.0 2.0 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 KUM64089.1 - 0.00012 21.9 2.2 0.43 10.6 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KUM64089.1 - 0.0048 15.9 0.3 4.7 6.1 0.0 3.8 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KUM64089.1 - 0.1 10.6 0.0 0.21 9.5 0.0 1.5 1 0 0 1 1 1 0 IKI3 family AMP-binding PF00501.28 KUM64090.1 - 1.2e-59 202.0 0.0 1.6e-59 201.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KUM64090.1 - 2.8e-51 174.2 0.0 4e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KUM64090.1 - 1.6e-15 57.2 0.0 3.5e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KUM64090.1 - 4.3e-12 46.2 0.0 1.3e-11 44.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KUM64090.1 - 2.7e-07 29.9 0.0 7.1e-07 28.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KUM64090.1 - 6.1e-06 25.9 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KUM64090.1 - 0.054 12.6 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PUA PF01472.20 KUM64091.1 - 5.6e-14 51.9 0.1 7.5e-14 51.5 0.1 1.2 1 0 0 1 1 1 1 PUA domain Pre-PUA PF17832.1 KUM64091.1 - 1.2e-09 38.7 0.2 1.7e-09 38.2 0.2 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain Rax2 PF12768.7 KUM64092.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity RIC1 PF07064.13 KUM64093.1 - 3.5e-85 285.4 0.1 5.1e-85 284.9 0.1 1.3 1 0 0 1 1 1 1 RIC1 SGTA_dimer PF16546.5 KUM64094.1 - 1.2e-24 85.9 0.1 2e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KUM64094.1 - 8.1e-16 57.1 7.7 3.1e-06 26.8 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KUM64094.1 - 4.7e-14 51.3 10.7 5.2e-05 23.0 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KUM64094.1 - 2.3e-10 39.8 8.4 8.9e-06 25.5 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KUM64094.1 - 2.8e-10 39.7 8.9 8.2e-09 35.0 0.7 3.1 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.6 KUM64094.1 - 1.7e-07 31.7 10.2 5.9e-05 23.6 6.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KUM64094.1 - 8.9e-07 29.1 4.9 0.00091 19.5 1.4 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KUM64094.1 - 1.1e-06 28.6 2.1 0.015 15.7 0.2 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KUM64094.1 - 1.5e-06 27.8 0.4 0.077 13.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KUM64094.1 - 4.4e-05 23.9 6.4 0.014 15.9 1.5 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat STI1 PF17830.1 KUM64094.1 - 0.00038 20.3 6.8 0.0032 17.4 2.2 2.9 3 0 0 3 3 3 1 STI1 domain TPR_14 PF13428.6 KUM64094.1 - 0.00086 19.9 10.6 1.1 10.3 2.4 3.7 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KUM64094.1 - 0.0012 19.0 2.3 0.013 15.6 1.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat XPC-binding PF09280.11 KUM64094.1 - 0.011 15.5 0.8 0.024 14.3 0.8 1.6 1 0 0 1 1 1 0 XPC-binding domain BTAD PF03704.17 KUM64094.1 - 0.056 13.9 3.1 0.11 12.9 1.1 2.2 2 0 0 2 2 2 0 Bacterial transcriptional activator domain MIT PF04212.18 KUM64094.1 - 0.057 13.5 0.8 2.1 8.5 0.1 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 KUM64094.1 - 0.12 13.1 7.0 0.31 11.8 0.2 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KUM64094.1 - 0.18 11.7 7.3 14 5.7 0.8 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Tim44 PF04280.15 KUM64095.1 - 5.6e-37 127.1 0.0 2.4e-36 125.1 0.0 2.0 2 0 0 2 2 2 1 Tim44-like domain Ribosomal_S11 PF00411.19 KUM64096.1 - 2.6e-06 27.8 0.0 6.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S11 VPS9 PF02204.18 KUM64097.1 - 1.1e-17 64.1 0.1 3.1e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 KUM64097.1 - 2.2e-16 59.7 0.9 1.6e-12 47.3 0.0 4.6 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KUM64097.1 - 1.2e-12 48.2 0.0 0.00015 22.3 0.1 3.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) PX PF00787.24 KUM64097.1 - 5.6e-07 29.5 0.3 1.6e-06 28.1 0.3 1.8 1 0 0 1 1 1 1 PX domain Ank PF00023.30 KUM64097.1 - 1.5e-05 25.2 0.4 0.68 10.5 0.1 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KUM64097.1 - 2.3e-05 24.8 0.0 0.015 15.9 0.0 3.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM64097.1 - 0.0095 16.4 0.2 34 5.4 0.0 4.9 5 0 0 5 5 5 0 Ankyrin repeat RNase_H PF00075.24 KUM64098.1 - 1.9e-15 57.3 0.0 2.6e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 RNase H Aldedh PF00171.22 KUM64100.1 - 1.1e-106 357.1 0.0 1.3e-106 356.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CHCH PF06747.13 KUM64101.1 - 5.4e-06 26.4 0.8 6.9e-06 26.1 0.8 1.1 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 KUM64101.1 - 0.0036 17.6 3.2 0.92 9.9 0.2 2.1 1 1 1 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 KUM64101.1 - 0.012 15.9 2.3 0.031 14.6 2.3 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 KUM64101.1 - 0.052 13.6 0.9 0.071 13.1 0.9 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, HDNR PF15115.6 KUM64102.1 - 0.09 13.0 0.3 0.11 12.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function with conserved HDNR motif adh_short PF00106.25 KUM64103.1 - 5.1e-16 58.7 0.0 4.2e-08 32.9 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM64103.1 - 2.1e-09 37.3 0.0 4.9e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM64103.1 - 0.00054 19.9 0.0 0.00087 19.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Aldo_ket_red PF00248.21 KUM64104.1 - 6.7e-48 163.4 0.0 9.7e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.14 KUM64106.1 - 5e-07 30.0 0.1 9.7e-07 29.0 0.1 1.5 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNF220 PF15926.5 KUM64108.1 - 0.48 10.0 0.0 0.48 10.0 0.0 1.9 3 0 0 3 3 3 0 E3 ubiquitin-protein ligase RNF220 Glyco_tranf_2_3 PF13641.6 KUM64109.1 - 3.1e-17 63.3 0.0 4.5e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KUM64109.1 - 4.5e-17 62.6 0.6 4.5e-17 62.6 0.6 2.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KUM64109.1 - 4.6e-13 49.3 0.0 8.5e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KUM64109.1 - 4.5e-06 26.3 0.0 7.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Oxidored_FMN PF00724.20 KUM64110.1 - 3e-63 214.2 0.0 3.5e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GPI-anchored PF10342.9 KUM64112.1 - 1e-19 71.1 1.4 1e-19 71.1 1.4 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF515 PF04415.12 KUM64112.1 - 5.7 5.2 12.5 6.4 5.1 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) TAL_FSA PF00923.19 KUM64113.1 - 2.7e-31 109.0 0.0 3.3e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Alpha-amylase PF00128.24 KUM64115.1 - 9.1e-52 176.7 3.3 1.3e-51 176.2 3.3 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KUM64115.1 - 2.4e-30 104.7 0.3 4.6e-30 103.7 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Alpha-amylase PF00128.24 KUM64116.1 - 5.2e-17 62.4 0.2 2.5e-16 60.2 0.2 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KUM64116.1 - 2.1e-15 57.1 0.1 4.1e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KUM64116.1 - 7.4e-05 22.3 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF4839 PF16127.5 KUM64116.1 - 0.027 14.6 1.2 1.1 9.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4839) Alpha-amylase PF00128.24 KUM64117.1 - 2.5e-25 89.8 0.0 5.3e-25 88.7 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KUM64117.1 - 1.1e-06 27.2 0.2 0.011 14.0 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Transferase PF02458.15 KUM64120.1 - 2.8e-17 62.5 0.0 2.9e-16 59.1 0.0 2.4 2 1 0 2 2 2 1 Transferase family Condensation PF00668.20 KUM64120.1 - 0.11 11.1 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Condensation domain PTH2 PF01981.16 KUM64121.1 - 6.7e-37 126.4 0.5 1.8e-32 112.1 0.0 2.2 2 0 0 2 2 2 2 Peptidyl-tRNA hydrolase PTH2 GOLD_2 PF13897.6 KUM64121.1 - 0.071 13.6 0.4 0.11 13.0 0.4 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking BSP_II PF05432.11 KUM64121.1 - 0.3 10.7 8.6 0.42 10.3 8.6 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 KUM64121.1 - 0.73 8.0 4.1 0.91 7.7 4.1 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KUM64121.1 - 6.8 5.9 6.2 10 5.3 6.2 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KUM64121.1 - 6.8 4.6 7.2 8.6 4.3 7.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi NAD_binding_2 PF03446.15 KUM64122.1 - 2e-30 106.0 0.0 2.8e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KUM64122.1 - 3.4e-22 79.0 0.0 5.3e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KUM64122.1 - 0.029 15.0 0.0 0.062 13.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Aminotran_1_2 PF00155.21 KUM64123.1 - 1.3e-92 310.8 0.0 1.5e-92 310.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SART-1 PF03343.13 KUM64124.1 - 5.3e-184 613.3 62.0 6.1e-184 613.1 62.0 1.0 1 0 0 1 1 1 1 SART-1 family Pyridoxal_deC PF00282.19 KUM64125.1 - 1.4e-18 66.8 0.0 2.1e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KUM64125.1 - 4.6e-09 35.7 0.0 4e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KUM64125.1 - 1.1e-06 28.1 0.0 1.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KUM64125.1 - 0.00019 20.8 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KUM64125.1 - 0.043 12.3 0.0 0.14 10.7 0.0 1.7 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Ribosomal_L30 PF00327.20 KUM64126.1 - 1e-15 57.3 0.2 1.3e-15 57.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e HMGL-like PF00682.19 KUM64128.1 - 5e-79 265.6 0.5 7e-79 265.1 0.5 1.2 1 0 0 1 1 1 1 HMGL-like DUF3666 PF12408.8 KUM64128.1 - 0.57 9.4 2.8 0.47 9.7 0.3 2.1 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase ELL PF10390.9 KUM64129.1 - 0.018 14.6 0.2 0.018 14.6 0.2 2.1 2 1 0 2 2 2 0 RNA polymerase II elongation factor ELL DUF4391 PF14335.6 KUM64129.1 - 0.04 13.6 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DUF155 PF02582.14 KUM64130.1 - 2.3e-52 177.6 0.0 3.7e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Fungal_trans_2 PF11951.8 KUM64134.1 - 4.3e-31 108.1 0.1 5.8e-31 107.7 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM64134.1 - 3.2e-08 33.6 6.9 6.7e-08 32.5 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.21 KUM64135.1 - 1.4e-89 300.6 0.0 1.9e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KUM64135.1 - 0.00029 20.1 0.0 0.0017 17.6 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II TonB_2 PF13103.6 KUM64135.1 - 0.047 13.9 0.0 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 TonB C terminal MFS_1 PF07690.16 KUM64136.1 - 1.5e-31 109.7 54.1 1.8e-26 92.9 34.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM64136.1 - 2.8e-17 62.7 27.4 5.4e-16 58.5 27.4 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter LacAB_rpiB PF02502.18 KUM64136.1 - 0.032 14.2 0.2 0.055 13.5 0.2 1.3 1 0 0 1 1 1 0 Ribose/Galactose Isomerase MFS_1 PF07690.16 KUM64137.1 - 8.3e-31 107.2 16.6 1.2e-30 106.6 16.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Homeodomain PF00046.29 KUM64139.1 - 4.3e-19 68.1 2.3 8.6e-19 67.1 2.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KUM64139.1 - 0.0048 16.8 0.7 0.01 15.7 0.7 1.5 1 0 0 1 1 1 1 Homeobox KN domain GFO_IDH_MocA PF01408.22 KUM64140.1 - 1e-13 52.1 0.0 2.1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KUM64140.1 - 0.00019 22.1 0.0 0.00035 21.2 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KUM64140.1 - 0.073 13.5 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KUM64141.1 - 1.1e-05 24.5 0.1 1.5e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM64141.1 - 0.00096 18.2 1.1 0.0015 17.5 1.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Fringe PF02434.16 KUM64142.1 - 1.7e-09 37.5 0.0 4.4e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 KUM64142.1 - 1.5e-07 31.1 0.1 5.1e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF604 SRP_TPR_like PF17004.5 KUM64143.1 - 1.3e-21 76.8 2.9 1e-20 73.9 1.3 2.3 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 KUM64143.1 - 2.6e-17 63.0 4.2 2.6e-17 63.0 4.2 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 KUM64143.1 - 8.1e-06 26.3 23.1 0.18 12.3 0.6 7.2 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KUM64143.1 - 3.7e-05 23.5 8.3 2.7 8.3 0.1 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM64143.1 - 4.5e-05 23.6 10.6 1.1 9.6 4.1 4.6 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KUM64143.1 - 0.0006 20.4 26.0 0.34 11.8 0.5 8.8 7 2 4 11 11 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 KUM64143.1 - 0.00082 19.4 4.0 8.9 6.8 0.1 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KUM64143.1 - 0.019 15.0 6.6 8.5 6.7 0.1 5.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 KUM64143.1 - 0.19 11.9 3.4 1.3 9.2 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KUM64143.1 - 0.27 11.6 14.1 8.1 6.8 0.2 5.9 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KUM64143.1 - 0.52 10.2 6.5 3.6 7.6 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KUM64143.1 - 0.6 10.9 9.4 66 4.5 0.3 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KUM64143.1 - 1.5 9.5 24.0 0.48 11.1 0.2 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat Cytochrom_B562 PF07361.11 KUM64143.1 - 2.3 8.9 5.2 4 8.1 1.9 2.8 2 0 0 2 2 2 0 Cytochrome b562 DUF478 PF04334.12 KUM64144.1 - 0.39 10.8 5.5 0.2 11.8 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF478) zf-C2H2 PF00096.26 KUM64145.1 - 7.5e-19 67.1 28.2 3.5e-05 24.0 1.7 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KUM64145.1 - 7.8e-19 67.2 28.1 1.4e-06 28.5 1.5 5.6 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KUM64145.1 - 2.9e-10 40.1 25.5 0.004 17.9 1.3 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KUM64145.1 - 8.5e-06 25.9 2.5 0.5 10.7 0.1 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KUM64145.1 - 0.00088 19.6 15.0 0.012 16.0 0.3 4.1 4 0 0 4 4 4 1 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KUM64145.1 - 0.0064 17.1 11.0 0.23 12.1 0.8 3.7 3 1 1 4 4 4 2 FOXP coiled-coil domain zf_UBZ PF18439.1 KUM64145.1 - 0.013 15.1 2.3 1.1 8.9 0.2 2.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KUM64145.1 - 0.019 14.7 0.8 0.019 14.7 0.8 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 KUM64145.1 - 0.021 14.9 1.1 2.9 8.0 0.1 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger Yippee-Mis18 PF03226.14 KUM64145.1 - 0.28 11.4 1.7 17 5.7 0.1 2.3 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF4764 PF15961.5 KUM64145.1 - 0.87 8.2 6.9 0.065 11.9 0.4 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4764) LIM PF00412.22 KUM64145.1 - 2.8 8.2 5.7 26 5.1 0.1 3.0 2 1 1 3 3 3 0 LIM domain HNH PF01844.23 KUM64145.1 - 6.9 6.9 8.4 7.8 6.8 0.1 3.8 4 0 0 4 4 4 0 HNH endonuclease Zn-ribbon_8 PF09723.10 KUM64145.1 - 10 6.4 9.3 88 3.3 4.4 3.1 1 1 2 3 3 3 0 Zinc ribbon domain PEP_mutase PF13714.6 KUM64146.1 - 2.2e-33 115.7 1.1 2.4e-33 115.6 1.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase TPR_10 PF13374.6 KUM64147.1 - 2.6e-05 24.0 3.1 0.28 11.1 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KUM64147.1 - 0.0022 18.0 2.9 0.92 9.8 0.7 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KUM64147.1 - 0.0032 17.7 5.4 14 6.1 0.1 5.3 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KUM64147.1 - 0.012 15.4 0.3 3.7 7.5 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_35 PF14516.6 KUM64147.1 - 0.1 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain vWA-TerF-like PF10138.9 KUM64148.1 - 0.00019 21.6 0.0 0.00029 21.0 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus PhoLip_ATPase_C PF16212.5 KUM64149.1 - 2.2e-70 237.3 21.2 2.2e-70 237.3 21.2 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KUM64149.1 - 2.8e-23 81.4 3.0 2.8e-22 78.2 0.5 2.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KUM64149.1 - 9.6e-13 48.0 0.1 9.6e-13 48.0 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KUM64149.1 - 2e-12 47.8 2.8 4.4e-06 27.1 0.2 3.8 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KUM64149.1 - 1.5e-11 44.2 0.0 2.1e-10 40.5 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KUM64149.1 - 0.0033 17.2 0.0 0.0081 15.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DPBB_1 PF03330.18 KUM64149.1 - 0.098 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Lytic transglycolase DUF1345 PF07077.11 KUM64149.1 - 0.36 10.5 5.1 8.3 6.1 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) RED_N PF07808.13 KUM64151.1 - 3.4e-07 30.1 1.3 8.1e-07 28.9 1.3 1.6 1 0 0 1 1 1 1 RED-like protein N-terminal region GvpG PF05120.12 KUM64151.1 - 3.3 7.8 4.9 0.85 9.7 0.4 2.3 2 0 0 2 2 2 0 Gas vesicle protein G AA_permease_2 PF13520.6 KUM64154.1 - 7.2e-23 81.1 7.4 8.6e-23 80.8 7.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM64154.1 - 2.2e-08 33.1 8.6 3.3e-08 32.6 8.6 1.2 1 1 0 1 1 1 1 Amino acid permease RseC_MucC PF04246.12 KUM64154.1 - 0.2 11.6 6.6 0.61 10.0 4.5 2.6 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC AA_permease_2 PF13520.6 KUM64155.1 - 4.7e-06 25.7 4.5 5.4e-06 25.5 4.5 1.0 1 0 0 1 1 1 1 Amino acid permease ABC2_membrane_5 PF13346.6 KUM64155.1 - 0.031 13.8 2.6 0.041 13.4 2.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein MFS_1 PF07690.16 KUM64156.1 - 1.9e-49 168.5 27.6 1.9e-49 168.5 27.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM64156.1 - 2.7e-20 72.7 3.6 2.7e-20 72.7 3.6 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3328 PF11807.8 KUM64156.1 - 2.3e-11 43.9 0.1 6.4e-11 42.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TRI12 PF06609.13 KUM64156.1 - 2.3e-10 39.5 3.0 3.8e-10 38.8 3.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KUM64156.1 - 0.6 8.9 8.0 0.099 11.5 2.8 2.2 2 0 0 2 2 2 0 MFS_1 like family AKAP7_NLS PF10469.9 KUM64157.1 - 5e-18 65.7 0.0 7.3e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Sec6 PF06046.13 KUM64158.1 - 4.8e-170 566.7 9.6 4.8e-170 566.7 9.6 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec6 Myb_DNA-bind_5 PF13873.6 KUM64158.1 - 0.22 11.6 1.1 42 4.3 0.0 3.5 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain HEAT_2 PF13646.6 KUM64158.1 - 0.31 11.5 2.3 1.6 9.1 0.2 3.4 3 1 0 3 3 3 0 HEAT repeats Steroid_dh PF02544.16 KUM64159.1 - 7.5e-13 48.7 0.8 7.5e-13 48.7 0.8 2.1 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase BRI3BP PF14965.6 KUM64159.1 - 0.001 18.6 0.8 0.001 18.6 0.8 2.7 4 0 0 4 4 4 1 Negative regulator of p53/TP53 YbgT_YccB PF08173.11 KUM64159.1 - 2.5 8.3 8.8 7.4 6.8 8.8 1.9 1 0 0 1 1 1 0 Membrane bound YbgT-like protein 2OG-FeII_Oxy_2 PF13532.6 KUM64160.1 - 5.1e-12 46.4 0.0 9.4e-12 45.5 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Stb3 PF10330.9 KUM64162.1 - 1.4e-39 134.0 0.0 2.2e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein RunxI PF08504.11 KUM64162.1 - 0.36 11.5 4.2 0.29 11.8 0.5 2.4 2 1 0 2 2 2 0 Runx inhibition domain Kri1_C PF12936.7 KUM64163.1 - 7.6e-32 109.3 1.1 7.6e-32 109.3 1.1 3.6 2 1 1 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.12 KUM64163.1 - 7.4e-28 97.1 15.6 7.4e-28 97.1 15.6 5.2 5 0 0 5 5 5 1 KRI1-like family Mito_carr PF00153.27 KUM64164.1 - 4.3e-66 218.9 5.8 2.1e-24 85.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sen15 PF09631.10 KUM64165.1 - 2.5e-12 46.9 0.0 1.4e-10 41.4 0.0 2.3 1 1 0 1 1 1 1 Sen15 protein VASt PF16016.5 KUM64166.1 - 1.2e-33 116.7 0.1 4.7e-33 114.8 0.1 2.0 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 KUM64166.1 - 3.5e-15 56.4 0.2 7.5e-15 55.3 0.2 1.5 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KUM64166.1 - 1.2e-09 38.6 0.4 5.1e-09 36.6 0.0 2.4 3 0 0 3 3 3 1 PH domain BAR PF03114.18 KUM64166.1 - 0.0024 17.6 0.1 0.0047 16.6 0.1 1.4 1 0 0 1 1 1 1 BAR domain GRAM PF02893.20 KUM64166.1 - 0.0037 17.1 0.0 0.0089 15.9 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Rotamase_3 PF13616.6 KUM64167.1 - 1.1e-17 64.6 1.3 2e-17 63.8 0.2 1.9 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase PF00639.21 KUM64167.1 - 1.7e-14 54.5 0.0 3.1e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KUM64167.1 - 2.4e-05 25.2 2.6 6.5e-05 23.8 0.0 2.0 1 1 1 2 2 2 1 PPIC-type PPIASE domain UAA PF08449.11 KUM64168.1 - 1.9e-43 148.8 11.2 6.9e-43 147.0 11.2 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KUM64168.1 - 1.6e-06 28.3 28.2 0.00071 19.8 8.3 3.5 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KUM64168.1 - 1e-05 24.9 0.8 0.061 12.5 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter DUF5090 PF17009.5 KUM64168.1 - 1.9 8.4 8.4 0.21 11.5 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) Ste5 PF11610.8 KUM64169.1 - 0.18 11.7 0.3 0.18 11.7 0.3 2.0 2 0 0 2 2 2 0 Scaffold protein Ste5, Fus3-binding region DUF2486 PF10667.9 KUM64169.1 - 4.9 7.3 10.1 3.3 7.9 5.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) PXA PF02194.15 KUM64171.1 - 1.2e-46 159.0 0.0 1.6e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 PXA domain IU_nuc_hydro PF01156.19 KUM64172.1 - 8.1e-80 268.6 0.0 9.7e-80 268.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Pkinase PF00069.25 KUM64173.1 - 1.4e-05 24.6 0.0 1.7e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM64173.1 - 0.014 14.7 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Vac_ImportDeg PF09783.9 KUM64175.1 - 8.2e-18 64.7 0.5 2.7e-17 63.0 0.5 1.8 2 0 0 2 2 2 1 Vacuolar import and degradation protein MMR_HSR1_Xtn PF16897.5 KUM64177.1 - 1.8e-38 130.8 1.1 6e-38 129.1 0.3 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KUM64177.1 - 2.3e-22 79.2 0.2 5.8e-22 77.9 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KUM64177.1 - 1.3e-19 69.9 0.1 3.1e-19 68.8 0.1 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KUM64177.1 - 7.8e-11 41.7 0.2 3.5e-10 39.6 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KUM64177.1 - 2.2e-05 24.6 0.1 0.15 12.1 0.0 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KUM64177.1 - 0.00065 19.3 0.2 11 5.5 0.1 3.9 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KUM64177.1 - 0.003 17.5 0.7 0.26 11.2 0.0 3.1 2 1 1 3 3 3 1 RsgA GTPase MeaB PF03308.16 KUM64177.1 - 0.011 14.8 0.1 0.024 13.6 0.1 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 KUM64177.1 - 0.011 15.0 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 AIG1 family Arf PF00025.21 KUM64177.1 - 0.025 14.0 0.2 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family HTH_Tnp_Tc5 PF03221.16 KUM64178.1 - 1.6e-14 53.6 0.0 3e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KUM64178.1 - 5.3e-05 22.8 0.1 0.00012 21.7 0.1 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 KUM64178.1 - 0.00044 20.0 0.0 0.001 18.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 KUM64178.1 - 0.018 15.0 0.1 0.098 12.6 0.0 2.2 2 0 0 2 2 2 0 MarR family HTH_Tnp_4 PF13613.6 KUM64178.1 - 0.035 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_IclR PF09339.10 KUM64178.1 - 0.049 13.4 0.0 4.2 7.3 0.0 2.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_10 PF04967.12 KUM64178.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_37 PF13744.6 KUM64178.1 - 0.15 12.1 0.0 4.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KUM64178.1 - 0.16 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain IBN_N PF03810.19 KUM64179.1 - 1.7e-15 56.7 1.3 4.3e-15 55.4 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KUM64179.1 - 5.5e-05 23.3 1.6 0.00081 19.5 0.0 2.9 2 1 0 2 2 2 1 Exportin 1-like protein Glyco_hydro_2_C PF02836.17 KUM64181.1 - 5.5e-15 55.3 0.1 9.6e-14 51.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KUM64181.1 - 1.5e-13 51.0 0.5 7.6e-13 48.7 0.2 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KUM64181.1 - 1.2e-12 48.5 0.4 1.2e-12 48.5 0.4 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KUM64181.1 - 0.014 15.9 0.4 1 9.9 0.1 2.5 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain SnoaL_2 PF12680.7 KUM64182.1 - 8.3e-11 42.4 0.1 1e-10 42.1 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KUM64182.1 - 0.018 15.4 0.0 0.025 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) CN_hydrolase PF00795.22 KUM64183.1 - 4.7e-37 127.7 0.0 5.5e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Cellulase PF00150.18 KUM64184.1 - 3.6e-19 69.3 2.1 8.5e-19 68.0 2.1 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Amino_oxidase PF01593.24 KUM64186.1 - 2.5e-72 244.6 0.1 1.7e-71 241.9 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KUM64186.1 - 8.5e-09 35.5 0.2 2.8e-08 33.9 0.1 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM64186.1 - 8.6e-05 21.9 0.1 0.028 13.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM64186.1 - 0.00017 22.1 0.3 0.16 12.5 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM64186.1 - 0.00068 19.0 0.5 0.016 14.4 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM64186.1 - 0.0011 18.6 2.2 0.035 13.7 0.4 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KUM64186.1 - 0.0067 15.7 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KUM64186.1 - 0.0068 16.4 0.3 3.6 7.5 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KUM64186.1 - 0.0078 15.5 0.7 0.087 12.1 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KUM64186.1 - 0.018 14.4 0.8 0.033 13.5 0.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KUM64186.1 - 0.16 11.3 0.3 0.48 9.7 0.1 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 KUM64186.1 - 0.21 10.6 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KUM64186.1 - 0.22 10.2 0.2 2.8 6.5 0.3 2.2 2 0 0 2 2 2 0 HI0933-like protein Zn_clus PF00172.18 KUM64188.1 - 0.023 14.8 14.7 0.04 14.0 14.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.7 KUM64189.1 - 1.2e-22 80.3 0.2 2.6e-12 47.2 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KUM64189.1 - 2.8e-17 62.5 1.1 9.3e-08 32.2 0.0 5.0 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KUM64189.1 - 5e-17 62.0 0.2 7.5e-07 29.6 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KUM64189.1 - 2.9e-13 49.6 1.5 0.0023 18.3 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 KUM64189.1 - 1.4e-11 43.5 0.3 0.005 17.2 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ribosomal_L7Ae PF01248.26 KUM64190.1 - 3.9e-27 93.8 0.6 4.6e-27 93.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KUM64190.1 - 0.089 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Zn_clus PF00172.18 KUM64191.1 - 5.3e-11 42.5 11.2 1e-10 41.6 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KUM64192.1 - 1.4e-39 136.0 40.9 1.7e-39 135.8 40.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM64192.1 - 7.5e-10 38.3 20.5 5.7e-09 35.4 20.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2207 PF09972.9 KUM64192.1 - 0.011 14.5 1.3 0.011 14.5 1.3 3.2 2 1 0 3 3 3 0 Predicted membrane protein (DUF2207) UPF0506 PF11703.8 KUM64193.1 - 0.021 15.2 18.4 0.021 15.2 18.4 4.3 3 1 1 4 4 4 0 UPF0506 Antifungal_pept PF11410.8 KUM64193.1 - 0.028 14.3 2.3 0.028 14.3 2.3 3.7 3 0 0 3 3 3 0 Antifungal peptide Dickkopf_N PF04706.12 KUM64193.1 - 6.3 7.4 55.3 6.5 7.3 18.1 5.4 4 2 1 5 5 5 0 Dickkopf N-terminal cysteine-rich region NMO PF03060.15 KUM64194.1 - 5.6e-37 127.9 2.6 1.9e-28 99.8 0.2 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KUM64194.1 - 6.3e-09 35.3 2.2 8.1e-08 31.6 2.2 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KUM64194.1 - 3e-07 29.8 4.7 1e-06 28.1 4.9 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KUM64194.1 - 2.8e-06 26.7 0.3 7.3e-06 25.4 0.3 1.6 1 1 0 1 1 1 1 Conserved region in glutamate synthase COesterase PF00135.28 KUM64196.1 - 3.4e-87 293.4 0.0 1.1e-86 291.8 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KUM64196.1 - 4.4e-11 43.0 0.3 2.4e-10 40.6 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KUM64196.1 - 0.00026 20.6 0.2 0.00056 19.4 0.2 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ribosomal_S19e PF01090.19 KUM64198.1 - 2.8e-54 182.5 0.1 3.9e-54 182.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_6 PF12697.7 KUM64199.1 - 1.8e-17 64.7 1.4 3.7e-17 63.7 1.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM64199.1 - 1e-14 54.8 0.0 5.4e-14 52.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM64199.1 - 1.3e-11 44.2 0.1 1.8e-08 34.0 0.0 3.0 3 0 0 3 3 3 2 Serine aminopeptidase, S33 DSPc PF00782.20 KUM64199.1 - 1e-08 35.0 0.0 2.4e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 KUM64199.1 - 3.2e-05 24.2 0.0 5.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 KUM64199.1 - 0.00015 21.6 0.1 0.026 14.4 0.2 2.4 1 1 1 2 2 2 1 Lipase (class 3) DUF1749 PF08538.10 KUM64199.1 - 0.00098 18.3 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) PTPlike_phytase PF14566.6 KUM64199.1 - 0.0013 18.8 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Ser_hydrolase PF06821.13 KUM64199.1 - 0.0026 17.7 0.5 0.03 14.2 0.1 2.7 2 1 0 2 2 2 1 Serine hydrolase PGAP1 PF07819.13 KUM64199.1 - 0.012 15.3 0.1 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 PGAP1-like protein FSH1 PF03959.13 KUM64199.1 - 0.013 15.2 0.0 0.62 9.7 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Y_phosphatase PF00102.27 KUM64199.1 - 0.053 13.1 0.0 0.21 11.1 0.0 2.0 3 0 0 3 3 3 0 Protein-tyrosine phosphatase Chlorophyllase2 PF12740.7 KUM64199.1 - 0.084 11.8 0.0 0.22 10.4 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme LCAT PF02450.15 KUM64199.1 - 0.09 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 KUM64199.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_4 PF08386.10 KUM64199.1 - 0.14 12.3 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein PCM1_C PF15717.5 KUM64199.1 - 1 8.0 4.5 1.6 7.4 4.5 1.2 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus ILVD_EDD PF00920.21 KUM64201.1 - 3.6e-212 705.6 0.3 4.2e-212 705.3 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1772 PF08592.11 KUM64202.1 - 7.9e-28 97.5 0.1 9.1e-28 97.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Pex2_Pex12 PF04757.14 KUM64203.1 - 3.5e-37 128.2 0.2 4.8e-37 127.7 0.2 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KUM64203.1 - 0.0026 17.9 5.5 0.005 17.0 5.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KUM64203.1 - 0.18 11.8 4.5 0.64 10.1 4.5 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KUM64203.1 - 2.5 8.0 6.9 1.1 9.2 2.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Aldedh PF00171.22 KUM64204.1 - 7.4e-159 529.1 0.1 8.3e-159 529.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KUM64204.1 - 0.0003 20.3 0.0 0.78 9.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Phosphoesterase PF04185.14 KUM64205.1 - 1e-35 123.6 6.6 6.1e-35 121.1 6.6 2.0 1 1 0 1 1 1 1 Phosphoesterase family HIF-1a_CTAD PF08778.10 KUM64205.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain Ureidogly_lyase PF04115.12 KUM64206.1 - 3.2e-63 212.9 0.0 3.7e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase BTB PF00651.31 KUM64207.1 - 3.9e-05 23.8 0.0 6.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF309 PF03745.14 KUM64207.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF309) Sec63 PF02889.16 KUM64208.1 - 3.2e-166 550.9 0.0 5e-93 311.0 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KUM64208.1 - 8.4e-50 169.0 0.1 1.4e-28 99.8 0.0 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KUM64208.1 - 1.5e-28 99.2 0.1 5.4e-28 97.4 0.1 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KUM64208.1 - 2.1e-22 79.9 0.0 1.2e-11 44.9 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KUM64208.1 - 1.5e-11 44.6 0.0 5.1e-07 30.0 0.0 3.7 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KUM64208.1 - 7.8e-06 26.2 0.9 0.041 14.2 0.1 3.6 3 1 0 3 3 3 2 AAA domain T2SSE PF00437.20 KUM64208.1 - 0.0009 18.4 0.0 1.1 8.3 0.0 2.7 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 KUM64208.1 - 0.012 15.1 0.0 0.78 9.2 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 KUM64208.1 - 0.15 12.4 0.1 11 6.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain MutS_V PF00488.21 KUM64209.1 - 3.4e-72 242.4 0.0 6.6e-72 241.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KUM64209.1 - 3.9e-43 147.9 4.9 9.6e-43 146.6 4.9 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KUM64209.1 - 1.1e-19 70.8 0.0 2.9e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KUM64209.1 - 1.4e-06 28.7 0.0 4.1e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain II CCDC92 PF14916.6 KUM64209.1 - 0.0057 16.4 0.1 0.029 14.1 0.0 2.2 2 0 0 2 2 2 1 Coiled-coil domain of unknown function AAA_29 PF13555.6 KUM64209.1 - 0.053 13.3 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KUM64209.1 - 0.068 13.7 0.1 0.33 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Peptidase_S9 PF00326.21 KUM64211.1 - 6.7e-50 169.5 0.1 1.5e-49 168.4 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KUM64211.1 - 0.00088 19.0 0.1 0.0017 18.1 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KUM64211.1 - 0.0032 16.2 0.1 0.11 11.2 0.1 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) PD40 PF07676.12 KUM64211.1 - 0.12 12.3 1.5 6.8 6.8 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat MFS_1 PF07690.16 KUM64212.1 - 7.3e-26 90.9 60.7 3.2e-24 85.5 31.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KUM64212.1 - 9.3 4.4 14.5 0.3 9.3 6.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Glyco_hydro_43 PF04616.14 KUM64213.1 - 1.6e-25 90.0 1.9 9.4e-16 58.0 0.7 2.3 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 RNase_P_p30 PF01876.16 KUM64214.1 - 1.4e-66 224.0 0.0 1.9e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Di19_C PF14571.6 KUM64214.1 - 0.22 12.1 1.3 0.41 11.2 1.3 1.4 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal Pkinase PF00069.25 KUM64215.1 - 4.4e-64 216.4 0.0 5.1e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM64215.1 - 7e-18 64.8 0.0 9.7e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KUM64215.1 - 3.4e-07 30.4 0.5 0.00011 22.2 0.1 2.7 2 1 0 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KUM64215.1 - 0.0031 16.3 0.0 0.0057 15.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KUM64215.1 - 0.0082 15.5 0.1 0.014 14.8 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KUM64215.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 KUM64215.1 - 0.025 14.1 0.6 0.047 13.3 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Aconitase_B_N PF11791.8 KUM64215.1 - 0.071 13.2 0.0 0.53 10.3 0.0 2.1 2 1 0 2 2 2 0 Aconitate B N-terminal domain Sugar_tr PF00083.24 KUM64216.1 - 3.5e-21 75.6 0.6 1.3e-20 73.7 0.6 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter PWWP PF00855.17 KUM64217.1 - 1.2e-16 60.9 2.8 3e-16 59.6 0.0 3.1 2 1 1 3 3 3 1 PWWP domain SpoIIE PF07228.12 KUM64218.1 - 1.8e-10 41.1 0.1 8.3e-10 38.9 0.1 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KUM64218.1 - 1.2e-07 31.6 0.1 2.3e-07 30.7 0.1 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KUM64218.1 - 2.5e-06 27.3 0.0 0.054 13.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SH3_1 PF00018.28 KUM64219.1 - 1.5e-33 114.2 6.7 5.2e-13 48.4 0.1 4.1 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 KUM64219.1 - 2.6e-32 110.4 0.2 4.5e-32 109.7 0.2 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 KUM64219.1 - 4.3e-31 106.5 8.1 2.8e-12 46.3 0.3 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KUM64219.1 - 5.5e-19 67.6 0.2 2.5e-07 30.3 0.0 4.1 4 0 0 4 4 4 3 Variant SH3 domain DUF1720 PF08226.11 KUM64219.1 - 7.4e-07 29.5 90.1 5.8e-06 26.6 40.5 7.5 3 1 5 8 8 8 3 Domain of unknown function (DUF1720) SAM_4 PF18017.1 KUM64219.1 - 2.2e-05 24.3 0.0 4.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 KUM64219.1 - 0.0004 20.4 0.0 0.85 9.7 0.0 3.4 3 0 0 3 3 3 1 SH3 domain SH3_3 PF08239.11 KUM64219.1 - 0.006 16.8 6.0 0.13 12.5 0.7 3.2 3 0 0 3 3 3 1 Bacterial SH3 domain Fungal_trans PF04082.18 KUM64220.1 - 3.6e-12 45.9 0.0 6.7e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Optomotor-blind PF11078.8 KUM64220.1 - 1.5 9.4 5.0 0.42 11.2 1.3 2.0 2 0 0 2 2 2 0 Optomotor-blind protein N-terminal region ComA PF02679.15 KUM64221.1 - 3.8e-81 272.1 0.0 4.3e-81 272.0 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) DUF2542 PF10808.8 KUM64221.1 - 0.12 12.9 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2542) PAP2_3 PF14378.6 KUM64222.1 - 1.4e-16 60.8 5.2 2.7e-08 33.7 1.2 2.6 3 0 0 3 3 3 2 PAP2 superfamily SNF2_N PF00176.23 KUM64223.1 - 1.6e-50 171.8 0.6 1.4e-49 168.7 0.5 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KUM64223.1 - 9.5e-17 61.3 0.0 3.5e-16 59.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM64223.1 - 4.6e-07 30.0 0.0 1.5e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KUM64223.1 - 1.4e-05 24.9 12.1 1.4e-05 24.9 12.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KUM64223.1 - 0.0016 18.2 10.7 0.0016 18.2 10.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 KUM64223.1 - 0.0021 17.0 0.0 0.0053 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DEAD PF00270.29 KUM64223.1 - 0.0064 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 KUM64223.1 - 0.014 15.7 12.4 0.014 15.7 12.4 2.6 2 0 0 2 2 2 0 Ring finger domain Zn_Tnp_IS91 PF14319.6 KUM64223.1 - 0.079 13.0 17.6 0.043 13.9 5.4 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain Osmo_CC PF08946.10 KUM64223.1 - 0.35 11.2 2.3 3.9 7.8 0.2 2.7 2 0 0 2 2 2 0 Osmosensory transporter coiled coil LRR_4 PF12799.7 KUM64224.1 - 3.4e-05 24.1 4.4 16 6.1 3.1 5.9 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KUM64224.1 - 0.023 14.7 12.4 0.093 12.8 0.0 6.5 9 0 0 9 9 9 0 Leucine Rich repeat INCENP_N PF12178.8 KUM64224.1 - 0.15 12.1 0.0 0.53 10.3 0.0 2.0 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal Pirin PF02678.16 KUM64225.1 - 6.7e-31 106.5 0.1 1.2e-30 105.7 0.1 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KUM64225.1 - 4.2e-23 81.7 0.0 1.6e-22 79.8 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KUM64225.1 - 1.1e-05 25.0 0.6 0.00015 21.4 1.1 2.3 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 KUM64225.1 - 0.062 13.0 0.1 0.85 9.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF861) PRKCSH PF07915.13 KUM64226.1 - 3.1e-19 69.8 0.2 3.1e-19 69.8 0.2 2.6 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KUM64226.1 - 0.00076 19.2 0.3 0.0049 16.6 0.3 2.0 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein adh_short_C2 PF13561.6 KUM64227.1 - 5.4e-24 85.0 0.6 7e-24 84.7 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM64227.1 - 2.4e-19 69.6 0.1 3.1e-19 69.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM64227.1 - 7.1e-06 26.0 0.4 1.5e-05 25.0 0.3 1.5 2 0 0 2 2 2 1 KR domain Abhydrolase_1 PF00561.20 KUM64229.1 - 7.6e-18 65.1 0.0 1.2e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KUM64229.1 - 4.1e-13 50.5 0.2 5.1e-13 50.1 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KUM64229.1 - 3.1e-05 24.2 0.0 4.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 KUM64229.1 - 0.073 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ndr PF03096.14 KUM64229.1 - 0.073 11.8 0.0 4.3 6.0 0.0 2.1 2 0 0 2 2 2 0 Ndr family LIDHydrolase PF10230.9 KUM64229.1 - 0.2 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase CorA PF01544.18 KUM64230.1 - 0.00028 20.3 6.2 0.00049 19.5 4.3 2.1 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein TNFR_16_TM PF18422.1 KUM64230.1 - 0.064 13.2 4.0 0.12 12.3 4.0 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF2207 PF09972.9 KUM64230.1 - 0.068 11.9 0.0 8.2 5.1 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) EamA PF00892.20 KUM64230.1 - 0.11 12.7 1.2 0.17 12.1 1.2 1.2 1 0 0 1 1 1 0 EamA-like transporter family MukF_M PF17192.4 KUM64230.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 MukF middle domain Pkinase PF00069.25 KUM64232.1 - 1.2e-18 67.4 0.0 3.4e-18 66.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KUM64232.1 - 1.7e-14 54.2 0.7 1.4e-09 38.4 0.1 4.0 2 1 3 5 5 5 3 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 KUM64232.1 - 7.8e-13 48.3 0.0 5.8e-12 45.4 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 KUM64232.1 - 1.2e-09 37.6 0.0 0.01 16.3 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KUM64232.1 - 4.5e-09 36.4 0.9 0.038 14.3 0.0 5.1 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KUM64232.1 - 6.5e-09 36.2 0.1 0.00043 20.8 0.0 4.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 KUM64232.1 - 1.1e-07 31.9 0.4 0.0014 19.0 0.0 5.0 4 1 1 5 5 5 1 Ankyrin repeat tRNA-synt_1 PF00133.22 KUM64234.1 - 7.2e-224 744.5 0.1 8.3e-223 741.0 0.1 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KUM64234.1 - 8.1e-31 107.0 1.8 2.9e-30 105.3 1.8 2.0 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KUM64234.1 - 2e-14 53.2 0.0 6.4e-07 28.5 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KUM64234.1 - 2.2e-08 33.8 0.0 7.6e-05 22.3 0.0 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 KUM64234.1 - 0.0064 16.8 7.6 0.0064 16.8 7.6 2.7 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm PepSY PF03413.19 KUM64234.1 - 0.044 14.3 3.5 0.37 11.4 0.0 2.9 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain tRNA-synt_1e PF01406.19 KUM64234.1 - 0.07 12.5 0.0 0.67 9.2 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 KUM64234.1 - 0.49 9.7 0.0 0.49 9.7 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) RelA_SpoT PF04607.17 KUM64236.1 - 1.6e-11 44.5 0.0 3.6e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins Serglycin PF04360.12 KUM64236.1 - 4e-05 23.6 0.1 7.7e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Serglycin Ank_4 PF13637.6 KUM64237.1 - 4e-20 71.9 2.5 2.8e-09 37.3 0.0 3.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KUM64237.1 - 8.1e-20 71.2 4.1 1e-12 48.5 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KUM64237.1 - 1.3e-11 44.4 1.0 0.0022 18.4 0.2 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KUM64237.1 - 3.8e-10 39.1 0.2 0.044 14.3 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KUM64237.1 - 2.1e-09 37.4 2.7 8.4e-05 22.8 0.2 3.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) DUF4743 PF15916.5 KUM64238.1 - 2.2e-10 40.5 0.0 3.8e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KUM64238.1 - 1.5e-07 31.5 0.0 2.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SLAC1 PF03595.17 KUM64239.1 - 2.8e-82 276.6 34.4 3.4e-82 276.3 34.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel HSCB_C PF07743.13 KUM64241.1 - 1.2e-20 73.7 1.2 1.8e-19 70.0 0.3 2.1 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KUM64241.1 - 2.6e-06 27.5 0.0 5.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 KUM64242.1 - 4.8e-30 103.1 19.8 1.6e-06 28.7 3.0 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat PRP4 PF08799.11 KUM64242.1 - 4e-14 51.9 6.6 4e-14 51.9 6.6 1.9 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 KUM64242.1 - 6.1e-09 36.1 0.1 0.33 11.3 0.0 5.0 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KUM64242.1 - 0.053 12.8 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 WD40-like domain CAP_GLY PF01302.25 KUM64243.1 - 4.9e-15 55.3 0.5 9.1e-15 54.4 0.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KUM64243.1 - 5.2e-11 42.1 10.6 4.6e-05 23.2 0.9 2.7 2 0 0 2 2 2 2 CLIP1 zinc knuckle FAM76 PF16046.5 KUM64243.1 - 0.0036 16.7 3.9 0.0036 16.7 3.9 3.1 1 1 1 3 3 3 1 FAM76 protein TMF_DNA_bd PF12329.8 KUM64243.1 - 0.0057 16.6 24.8 2.6 8.1 1.2 5.1 5 0 0 5 5 5 3 TATA element modulatory factor 1 DNA binding DUF812 PF05667.11 KUM64243.1 - 0.0058 15.6 15.7 0.0058 15.6 15.7 2.5 1 1 0 2 2 2 1 Protein of unknown function (DUF812) DUF3552 PF12072.8 KUM64243.1 - 0.012 15.1 35.9 0.013 14.9 6.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3552) AAA_13 PF13166.6 KUM64243.1 - 0.03 13.0 20.5 0.0043 15.8 12.2 2.6 2 1 0 2 2 2 0 AAA domain DUF3584 PF12128.8 KUM64243.1 - 0.075 10.5 25.6 0.37 8.2 20.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) EzrA PF06160.12 KUM64243.1 - 0.077 11.2 23.8 0.0061 14.8 9.6 2.9 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 KUM64243.1 - 0.22 10.4 30.9 1.4 7.7 6.8 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KUM64243.1 - 0.24 11.5 33.8 0.24 11.5 13.6 3.5 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KUM64243.1 - 0.25 11.4 17.9 0.16 12.0 4.4 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) AAA_assoc_2 PF16193.5 KUM64243.1 - 0.51 10.7 2.6 0.6 10.5 0.3 2.3 2 0 0 2 2 1 0 AAA C-terminal domain SlyX PF04102.12 KUM64243.1 - 0.54 10.9 30.3 1.2 9.8 6.4 4.1 3 0 0 3 3 3 0 SlyX Fez1 PF06818.15 KUM64243.1 - 0.56 10.6 35.4 0.052 14.0 13.9 3.4 1 1 1 3 3 3 0 Fez1 Pox_A_type_inc PF04508.12 KUM64243.1 - 0.65 9.9 16.3 1.5 8.8 2.8 4.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat NPV_P10 PF05531.12 KUM64243.1 - 0.67 10.4 13.5 2.4 8.7 1.2 3.6 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.11 KUM64243.1 - 0.76 10.0 37.6 12 6.0 13.3 3.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) CC2-LZ PF16516.5 KUM64243.1 - 0.83 10.1 27.7 0.26 11.7 0.5 3.6 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Prominin PF05478.11 KUM64243.1 - 1 7.3 3.7 2 6.3 3.7 1.5 1 0 0 1 1 1 0 Prominin Lebercilin PF15619.6 KUM64243.1 - 1.3 8.6 32.9 0.43 10.2 1.1 2.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF241 PF03087.14 KUM64243.1 - 1.5 8.6 10.8 8.2 6.2 7.9 2.6 2 1 0 2 2 2 0 Arabidopsis protein of unknown function Golgin_A5 PF09787.9 KUM64243.1 - 1.9 7.9 33.1 3.6 7.0 11.4 3.3 2 1 1 3 3 3 0 Golgin subfamily A member 5 Csm1_N PF18504.1 KUM64243.1 - 2.8 8.4 25.3 20 5.6 0.5 5.9 4 1 1 6 6 5 0 Csm1 N-terminal domain C1_2 PF03107.16 KUM64243.1 - 3.1 8.2 4.8 20 5.6 0.3 2.4 2 0 0 2 2 2 0 C1 domain Atg14 PF10186.9 KUM64243.1 - 3.6 6.6 26.3 3.4 6.7 9.9 3.5 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 KUM64243.1 - 4.9 7.5 21.1 0.62 10.4 4.4 3.9 3 1 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cauli_AT PF03233.13 KUM64243.1 - 5 7.0 11.1 0.42 10.5 1.4 3.0 2 1 1 3 3 3 0 Aphid transmission protein zf_PR_Knuckle PF18445.1 KUM64243.1 - 5.9 6.8 5.0 11 5.9 0.6 2.4 2 0 0 2 2 2 0 PR zinc knuckle motif Fib_alpha PF08702.10 KUM64243.1 - 6.6 6.9 15.8 19 5.4 0.1 3.7 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.11 KUM64243.1 - 8.5 6.2 24.1 3.5 7.4 4.3 3.6 2 1 2 4 4 4 0 Phage minor structural protein GP20 Exonuc_VII_L PF02601.15 KUM64243.1 - 9.2 5.7 23.6 23 4.4 2.3 2.9 1 1 1 2 2 2 0 Exonuclease VII, large subunit 3-HAO PF06052.12 KUM64244.1 - 7.7e-55 184.7 0.0 9.1e-55 184.4 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KUM64244.1 - 0.0005 19.7 0.0 0.00086 19.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KUM64244.1 - 0.0026 17.4 0.1 0.0036 16.9 0.1 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KUM64244.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain RTC_insert PF05189.13 KUM64245.1 - 1.4e-27 96.2 0.0 2.5e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 KUM64245.1 - 1e-26 93.6 0.1 1.2e-26 93.3 0.1 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase AvrPto PF11592.8 KUM64245.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto KR PF08659.10 KUM64247.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KUM64247.1 - 0.009 15.6 0.0 0.039 13.5 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Peptidase_M22 PF00814.25 KUM64247.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 1 0 1 1 1 0 Glycoprotease family Glyco_tranf_2_3 PF13641.6 KUM64247.1 - 0.18 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Pkinase PF00069.25 KUM64248.1 - 7e-35 120.7 0.0 9.4e-20 71.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KUM64248.1 - 7.9e-13 48.3 0.0 2.8e-06 26.8 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KUM64248.1 - 0.011 15.0 0.0 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KUM64248.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family UQ_con PF00179.26 KUM64249.1 - 1.3e-08 34.6 0.0 1.5e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Dicty_CAD PF05720.12 KUM64250.1 - 0.27 11.2 0.3 0.45 10.5 0.3 1.4 1 0 0 1 1 1 0 Cell-cell adhesion domain MFS_1 PF07690.16 KUM64251.1 - 3e-39 135.0 75.6 2.8e-34 118.6 48.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM64251.1 - 0.00015 20.8 12.0 0.00015 20.8 12.0 3.3 2 2 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KUM64251.1 - 0.0086 15.0 28.8 0.16 10.8 7.2 2.2 2 0 0 2 2 2 2 MFS_1 like family Peptidase_M24 PF00557.24 KUM64252.1 - 4.2e-47 160.5 0.0 5.2e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KUM64252.1 - 1.1e-21 76.9 6.8 2e-21 76.0 6.8 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KUM64252.1 - 0.0016 18.5 5.8 0.0037 17.3 5.8 1.7 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.7 KUM64253.1 - 3e-05 23.8 1.6 0.00037 20.3 0.0 3.0 3 0 0 3 3 3 1 F-box-like PRANC PF09372.10 KUM64253.1 - 0.0063 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 PRANC domain F-box PF00646.33 KUM64253.1 - 0.014 15.3 0.4 0.14 12.0 0.0 2.5 2 0 0 2 2 2 0 F-box domain MFS_1 PF07690.16 KUM64254.1 - 5.3e-38 130.8 46.0 1.1e-37 129.8 27.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily AOX PF01786.17 KUM64254.1 - 0.15 11.6 0.5 8.8 5.8 0.0 2.4 2 0 0 2 2 2 0 Alternative oxidase MWFE PF15879.5 KUM64254.1 - 0.17 12.1 0.2 0.17 12.1 0.2 3.0 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit UQ_con PF00179.26 KUM64256.1 - 4.7e-06 26.3 0.1 6e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme 3Beta_HSD PF01073.19 KUM64257.1 - 5.4e-44 150.3 0.0 1.1e-39 136.1 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KUM64257.1 - 3.9e-19 69.1 0.3 1.9e-16 60.3 0.0 2.4 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM64257.1 - 3.6e-14 52.9 0.2 7e-12 45.4 0.1 2.6 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KUM64257.1 - 3.5e-10 39.5 0.0 8e-08 31.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KUM64257.1 - 5.4e-06 25.7 0.1 1.5e-05 24.3 0.1 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KUM64257.1 - 0.047 12.8 0.0 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FSH1 PF03959.13 KUM64259.1 - 2.1e-31 109.2 0.0 2.8e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KUM64259.1 - 0.0012 19.5 0.5 0.0015 19.2 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KUM64259.1 - 0.0047 16.8 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Aldedh PF00171.22 KUM64260.1 - 2.6e-143 477.9 0.0 2.9e-143 477.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.19 KUM64261.1 - 5.2e-60 203.3 0.2 6.9e-60 202.9 0.2 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM64261.1 - 8.4e-34 117.2 0.0 1.5e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KUM64261.1 - 3.1e-05 24.1 0.2 0.00013 22.1 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KUM64261.1 - 0.00045 19.4 0.3 0.0012 18.0 0.2 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KUM64261.1 - 0.00056 19.2 0.1 0.001 18.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KUM64261.1 - 0.001 17.9 0.1 0.0019 17.0 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KUM64261.1 - 0.0014 18.0 0.2 0.014 14.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM64261.1 - 0.0027 18.2 0.6 0.0089 16.6 0.6 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM64261.1 - 0.0065 16.1 1.2 0.0084 15.7 0.4 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KUM64261.1 - 0.012 14.9 0.0 2.8 7.1 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM64261.1 - 0.014 14.5 0.1 0.035 13.2 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KUM64261.1 - 0.075 13.0 0.2 0.23 11.5 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KUM64261.1 - 0.082 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase RNase_T PF00929.24 KUM64262.1 - 1.6e-08 35.3 0.0 1.5e-07 32.1 0.0 2.1 1 1 0 1 1 1 1 Exonuclease Glutaredoxin PF00462.24 KUM64263.1 - 4.8e-19 68.3 0.0 1.2e-17 63.8 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KUM64263.1 - 1e-11 44.7 0.0 2.2e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KUM64263.1 - 0.00052 20.3 0.0 0.014 15.7 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like SnoaL_2 PF12680.7 KUM64266.1 - 0.0026 18.3 0.0 0.0038 17.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.16 KUM64267.1 - 9.6e-43 146.4 35.0 9.6e-43 146.4 35.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4112 PF13430.6 KUM64267.1 - 8 6.8 6.4 1.5 9.1 0.1 2.8 2 2 1 3 3 3 0 Domain of unknown function (DUF4112) DUF373 PF04123.13 KUM64267.1 - 9.6 5.5 8.9 3.6 7.0 4.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DLH PF01738.18 KUM64268.1 - 1.3e-28 100.0 0.0 1.6e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family ketoacyl-synt PF00109.26 KUM64269.1 - 1.7e-72 244.1 0.0 4.2e-72 242.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KUM64269.1 - 3.6e-31 107.6 0.0 1.1e-30 106.0 0.0 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KUM64269.1 - 2.6e-25 89.6 0.0 5.3e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KUM64269.1 - 7.8e-25 87.5 0.0 1.6e-24 86.5 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 KUM64269.1 - 9.1e-25 86.8 9.4 1.1e-12 48.1 2.2 3.4 3 0 0 3 3 2 2 Phosphopantetheine attachment site HTH_51 PF18558.1 KUM64269.1 - 8.1e-20 70.5 0.0 2.5e-19 68.9 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain SAT PF16073.5 KUM64269.1 - 5.3e-13 49.3 10.6 7.4e-12 45.5 2.9 3.7 3 1 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_12 PF08242.12 KUM64269.1 - 1.9e-10 41.3 0.1 7.7e-10 39.4 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM64269.1 - 4.6e-08 33.7 0.1 3.4e-07 30.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM64269.1 - 1.2e-07 31.8 0.0 3.3e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KUM64269.1 - 1.3e-07 31.3 0.0 2.6e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.12 KUM64269.1 - 5.1e-07 30.3 0.0 6.7e-06 26.7 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.23 KUM64269.1 - 1.3e-06 28.0 0.1 2.6e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 KUM64269.1 - 7.9e-06 25.7 0.0 2.2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KR PF08659.10 KUM64269.1 - 0.0006 19.8 0.1 0.002 18.1 0.1 1.9 1 0 0 1 1 1 1 KR domain KAsynt_C_assoc PF16197.5 KUM64269.1 - 0.0019 18.6 0.0 0.005 17.3 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Polysacc_synt_2 PF02719.15 KUM64269.1 - 0.056 12.6 0.0 0.18 10.9 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FAD_binding_3 PF01494.19 KUM64270.1 - 9.7e-21 74.4 0.8 1.3e-19 70.7 0.8 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KUM64270.1 - 0.00033 20.8 1.8 0.0015 18.7 1.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KUM64270.1 - 0.0079 16.1 1.7 0.013 15.4 1.7 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KUM64270.1 - 0.014 15.3 0.0 0.053 13.5 0.0 2.0 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KUM64270.1 - 0.018 15.6 1.6 0.018 15.6 1.6 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM64270.1 - 0.021 14.4 0.8 0.033 13.8 0.8 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Rossmann-like PF10727.9 KUM64270.1 - 0.056 13.3 0.3 0.15 11.9 0.3 1.6 1 0 0 1 1 1 0 Rossmann-like domain Lycopene_cycl PF05834.12 KUM64270.1 - 0.1 11.6 0.5 7.2 5.5 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KUM64270.1 - 0.59 8.9 2.6 8.8 5.1 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase SIS PF01380.22 KUM64271.1 - 1.2e-06 28.4 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 SIS domain DUF1492 PF07374.11 KUM64271.1 - 0.07 13.3 0.3 0.11 12.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) p450 PF00067.22 KUM64272.1 - 5.8e-46 157.2 0.0 3.2e-45 154.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 DIOX_N PF14226.6 KUM64273.1 - 2.5e-32 112.1 0.0 3.4e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KUM64273.1 - 2.5e-19 69.6 0.0 4.2e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 KUM64274.1 - 4.1e-13 49.0 5.9 6e-13 48.4 5.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KUM64275.1 - 2.6e-21 76.3 6.5 4.7e-11 42.5 0.1 2.8 1 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KUM64275.1 - 3.2e-09 36.9 0.4 7.6e-09 35.7 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM64275.1 - 8.8e-08 31.7 1.2 1e-06 28.2 1.3 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM64275.1 - 4.2e-07 29.4 2.1 4.2e-07 29.4 2.1 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KUM64275.1 - 1.9e-06 27.7 1.5 0.00013 21.6 0.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KUM64275.1 - 1.5e-05 24.6 0.6 2e-05 24.2 0.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KUM64275.1 - 1.6e-05 23.8 1.9 1.8e-05 23.6 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KUM64275.1 - 0.00014 21.1 1.4 0.0002 20.6 1.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KUM64275.1 - 0.0011 19.5 0.8 0.0026 18.3 0.8 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KUM64275.1 - 0.0026 17.1 1.5 0.0031 16.9 0.5 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KUM64275.1 - 0.0031 16.4 1.6 0.0068 15.3 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 KUM64275.1 - 0.0041 16.4 0.1 0.0068 15.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 KUM64275.1 - 0.0042 16.4 0.1 0.0042 16.4 0.1 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KUM64275.1 - 0.0048 16.0 4.3 0.035 13.2 4.3 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KUM64275.1 - 0.0073 15.6 0.9 0.014 14.7 0.9 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM64275.1 - 0.0084 16.1 1.0 0.29 11.1 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.10 KUM64275.1 - 0.062 12.3 0.0 0.36 9.8 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase 3HCDH_N PF02737.18 KUM64275.1 - 0.2 11.5 0.2 0.36 10.7 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MCRA PF06100.11 KUM64275.1 - 0.23 10.2 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 MCRA family adh_short PF00106.25 KUM64276.1 - 1.4e-32 112.8 0.0 2.2e-25 89.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM64276.1 - 1.9e-19 70.2 0.0 1.9e-14 53.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM64276.1 - 1.7e-09 37.8 0.0 2.5e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 KR domain TauD PF02668.16 KUM64277.1 - 1.8e-48 165.7 0.6 2.7e-48 165.1 0.6 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KUM64277.1 - 8.3e-07 29.6 0.1 2e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KUM64277.1 - 0.0019 17.4 0.1 0.0053 15.9 0.1 1.6 1 1 0 1 1 1 1 CsiD Nbl1_Borealin_N PF10444.9 KUM64280.1 - 2.1e-18 65.7 3.6 2.1e-18 65.7 3.6 1.6 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal RhoGAP PF00620.27 KUM64281.1 - 5.9e-35 120.3 0.3 1.1e-34 119.5 0.3 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KUM64281.1 - 3.9e-25 87.8 42.3 5.2e-11 42.6 6.0 4.8 5 0 0 5 5 5 4 LIM domain DUF1272 PF06906.11 KUM64281.1 - 0.0024 17.9 0.2 0.0024 17.9 0.2 4.1 3 1 1 4 4 4 1 Protein of unknown function (DUF1272) T2SSE PF00437.20 KUM64281.1 - 0.03 13.4 0.1 0.048 12.7 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein zinc_ribbon_12 PF11331.8 KUM64281.1 - 0.18 11.6 9.5 1.2 9.0 0.1 3.6 3 0 0 3 3 3 0 Probable zinc-ribbon domain Sybindin PF04099.12 KUM64282.1 - 1.1e-46 158.4 0.0 2e-46 157.4 0.0 1.4 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KUM64282.1 - 4.3e-07 30.1 0.0 7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region VWA_2 PF13519.6 KUM64283.1 - 5.3e-20 72.1 0.2 1.8e-19 70.4 0.1 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KUM64283.1 - 0.00011 22.5 0.4 0.00017 21.9 0.4 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KUM64283.1 - 0.0003 20.7 0.1 0.00044 20.1 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KUM64283.1 - 0.045 13.7 0.1 0.18 11.8 0.1 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif PDH PF02153.17 KUM64283.1 - 0.083 11.9 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase MMtag PF10159.9 KUM64286.1 - 0.062 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Multiple myeloma tumor-associated Ank_2 PF12796.7 KUM64287.1 - 0.00026 21.5 0.0 0.00087 19.8 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM64287.1 - 0.00043 20.8 0.1 0.0034 17.9 0.0 2.6 2 2 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KUM64287.1 - 0.074 13.5 0.0 0.33 11.5 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeat Fungal_trans PF04082.18 KUM64290.1 - 1.1e-22 80.4 0.1 1.6e-22 79.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM64290.1 - 6e-09 35.9 9.6 1.6e-08 34.5 9.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KUM64291.1 - 4.8e-58 196.6 0.0 4.9e-39 134.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KUM64291.1 - 2.8e-26 92.3 0.0 2.7e-19 69.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KUM64291.1 - 1.4e-12 47.8 0.0 2.7e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KUM64291.1 - 6.3e-08 32.3 0.3 0.00012 21.5 0.0 2.9 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 KUM64291.1 - 2e-06 27.9 0.0 0.0042 17.0 0.2 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KUM64291.1 - 0.0059 16.0 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KUM64291.1 - 0.0088 15.0 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain PAS_9 PF13426.7 KUM64291.1 - 0.089 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 PAS domain Seadorna_VP7 PF07387.11 KUM64291.1 - 0.11 11.5 0.1 0.2 10.6 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 KUM64291.1 - 0.13 11.8 0.0 21 4.6 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MS_channel PF00924.18 KUM64292.1 - 1.1e-25 90.4 2.3 2.1e-25 89.5 2.3 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 KUM64292.1 - 0.00028 20.2 0.0 0.00068 19.0 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KUM64292.1 - 0.0015 18.0 0.3 0.0036 16.7 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KUM64292.1 - 0.0021 17.8 0.0 0.0073 16.2 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KUM64292.1 - 0.019 15.4 0.2 0.06 13.8 0.2 1.8 1 0 0 1 1 1 0 EF-hand domain pair Tubulin PF00091.25 KUM64293.1 - 1.8e-65 220.9 0.0 2.4e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KUM64293.1 - 1.3e-43 148.2 0.0 2e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KUM64293.1 - 0.0015 18.3 0.0 0.0037 17.0 0.0 1.6 2 0 0 2 2 2 1 Tubulin domain Mito_carr PF00153.27 KUM64294.1 - 2e-63 210.3 1.6 1.1e-21 76.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 KUM64294.1 - 0.0015 18.7 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 2 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Sugar_tr PF00083.24 KUM64296.1 - 1.5e-108 363.6 23.6 1.7e-108 363.4 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM64296.1 - 4.5e-24 85.0 25.8 5.6e-22 78.1 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_17 PF00332.18 KUM64297.1 - 4e-06 26.6 1.5 1.1e-05 25.3 1.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DAP_B PF07930.12 KUM64300.1 - 1.9e-72 243.0 0.0 2.7e-72 242.6 0.0 1.2 1 0 0 1 1 1 1 D-aminopeptidase, domain B Beta-lactamase PF00144.24 KUM64300.1 - 7.3e-41 140.5 0.0 9.8e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Retrotran_gag_3 PF14244.6 KUM64302.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type MFS_1 PF07690.16 KUM64303.1 - 2.1e-29 102.5 36.5 3e-25 88.9 12.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_5_1 PF06946.11 KUM64303.1 - 0.61 10.5 4.3 1.9 8.9 0.3 2.7 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 TraL PF07178.11 KUM64303.1 - 1.2 9.7 12.7 5.7 7.5 0.7 3.9 3 0 0 3 3 3 0 TraL protein DAO PF01266.24 KUM64304.1 - 8.5e-44 150.6 0.1 1.1e-43 150.2 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KUM64304.1 - 0.0016 18.6 0.7 0.004 17.4 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 KUM64304.1 - 0.2 10.4 0.2 0.31 9.8 0.2 1.3 1 0 0 1 1 1 0 MCRA family ATG22 PF11700.8 KUM64306.1 - 1.4e-131 439.4 28.1 1.7e-131 439.2 28.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KUM64306.1 - 3.1e-08 32.9 37.0 7.2e-05 21.9 10.0 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily VbhA PF18495.1 KUM64306.1 - 0.034 14.0 0.3 0.079 12.8 0.2 1.6 2 0 0 2 2 2 0 Antitoxin VbhA 2-oxoacid_dh PF00198.23 KUM64307.1 - 3.6e-78 262.2 0.4 6e-78 261.5 0.4 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KUM64307.1 - 3.2e-17 62.1 1.4 7.1e-17 61.0 1.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KUM64307.1 - 0.00015 21.5 1.2 0.00015 21.5 1.2 1.8 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KUM64307.1 - 0.00065 20.4 1.1 0.066 13.9 0.6 2.5 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 KUM64307.1 - 0.015 14.6 1.9 0.051 12.8 0.1 2.5 2 1 1 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Presenilin PF01080.17 KUM64307.1 - 0.65 8.7 3.6 0.91 8.2 3.6 1.1 1 0 0 1 1 1 0 Presenilin Ribonuc_L-PSP PF01042.21 KUM64308.1 - 3.2e-31 107.8 0.3 4e-31 107.5 0.3 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Aldedh PF00171.22 KUM64309.1 - 6.8e-103 344.6 0.0 8.3e-103 344.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.18 KUM64310.1 - 7.3e-62 209.6 0.1 8.5e-62 209.4 0.1 1.0 1 0 0 1 1 1 1 Proline dehydrogenase alpha-hel2 PF14456.6 KUM64310.1 - 0.061 12.6 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 Fungal_trans PF04082.18 KUM64311.1 - 4.6e-13 48.8 0.0 8e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM64311.1 - 3.8e-07 30.1 11.9 7e-07 29.3 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG2_CAD PF13329.6 KUM64311.1 - 0.036 13.8 0.5 0.065 13.0 0.5 1.3 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif OxoGdeHyase_C PF16870.5 KUM64312.1 - 6.1e-37 126.7 0.1 6.7e-37 126.5 0.1 1.0 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Clathrin PF00637.20 KUM64314.1 - 5.6e-25 87.9 0.9 5.7e-22 78.1 1.1 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.8 KUM64314.1 - 5.2e-18 65.0 0.7 1.2e-17 63.9 0.7 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KUM64314.1 - 1.6e-07 31.2 7.0 3e-07 30.3 7.0 1.5 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 KUM64314.1 - 5.8e-06 26.1 6.3 1.2e-05 25.0 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.6 KUM64314.1 - 2.6e-05 24.7 0.1 0.023 15.5 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-RING_5 PF14634.6 KUM64314.1 - 0.00048 20.0 5.2 0.00096 19.1 5.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.6 KUM64314.1 - 0.00062 19.4 0.1 0.0023 17.6 0.1 2.0 1 0 0 1 1 1 1 TPR repeat zf-RING_2 PF13639.6 KUM64314.1 - 0.0027 18.0 6.3 0.0051 17.1 6.3 1.5 1 0 0 1 1 1 1 Ring finger domain Katanin_con80 PF13925.6 KUM64314.1 - 0.0048 16.9 0.0 9.5 6.2 0.0 3.5 3 0 0 3 3 3 0 con80 domain of Katanin DUF4810 PF16068.5 KUM64314.1 - 0.0099 16.4 0.5 3.3 8.3 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4810) zf-rbx1 PF12678.7 KUM64314.1 - 0.014 15.7 4.4 0.026 14.8 4.4 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain TPR_16 PF13432.6 KUM64314.1 - 0.02 15.5 0.1 0.12 13.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4 PF00097.25 KUM64314.1 - 0.042 13.7 4.6 0.08 12.8 4.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KUM64314.1 - 0.083 12.9 4.4 0.17 11.9 4.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Vps39_2 PF10367.9 KUM64314.1 - 0.096 13.1 3.0 0.085 13.3 0.6 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 TPR_12 PF13424.6 KUM64314.1 - 0.72 10.2 2.5 0.78 10.1 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM64314.1 - 0.79 10.0 3.3 1.9 8.8 0.1 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KUM64314.1 - 1.5 9.1 6.0 0.25 11.5 0.3 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-RING_6 PF14835.6 KUM64314.1 - 6 6.8 5.4 1.2 9.1 1.6 1.7 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Nha1_C PF08619.10 KUM64315.1 - 2e-105 353.7 48.6 2e-105 353.7 48.6 1.9 1 1 1 2 2 2 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 KUM64315.1 - 1.7e-74 250.9 15.7 2.1e-74 250.6 15.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Serglycin PF04360.12 KUM64315.1 - 0.0091 16.0 5.9 0.02 14.8 5.9 1.5 1 0 0 1 1 1 1 Serglycin DUF21 PF01595.20 KUM64315.1 - 0.19 11.4 6.0 0.029 14.1 1.5 2.0 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain YrhC PF14143.6 KUM64315.1 - 0.37 10.9 2.4 0.38 10.9 0.4 2.1 2 0 0 2 2 2 0 YrhC-like protein RAP1 PF07218.11 KUM64315.1 - 3.8 5.7 7.0 7 4.8 7.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PX PF00787.24 KUM64316.1 - 7.8e-17 61.3 0.1 1.6e-16 60.2 0.1 1.5 1 0 0 1 1 1 1 PX domain Prefoldin_3 PF13758.6 KUM64316.1 - 0.0037 17.3 1.3 0.018 15.1 0.1 2.5 2 0 0 2 2 2 1 Prefoldin subunit Tmemb_cc2 PF10267.9 KUM64316.1 - 0.012 14.8 0.2 0.019 14.2 0.2 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Arv1 PF04161.13 KUM64317.1 - 2.1e-60 204.5 0.3 1.3e-51 175.8 0.0 2.4 2 1 1 3 3 3 2 Arv1-like family LRR_4 PF12799.7 KUM64319.1 - 1.2e-24 85.9 43.1 4.8e-06 26.8 0.8 9.1 4 2 8 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KUM64319.1 - 2e-22 78.7 38.5 6.7e-07 29.0 4.6 7.8 4 1 6 10 10 10 7 Leucine rich repeat LRR_9 PF14580.6 KUM64319.1 - 5.6e-09 35.7 15.1 0.011 15.3 0.9 4.5 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KUM64319.1 - 3.6e-05 23.5 32.9 0.57 10.4 0.0 9.7 11 0 0 11 11 11 4 Leucine Rich repeat LRR_1 PF00560.33 KUM64319.1 - 0.0035 17.7 32.6 4.4 8.2 0.0 10.8 9 3 0 9 9 9 2 Leucine Rich Repeat Cupin_1 PF00190.22 KUM64320.1 - 1e-21 77.1 0.0 2.2e-20 72.8 0.0 2.0 2 0 0 2 2 2 1 Cupin Cupin_2 PF07883.11 KUM64320.1 - 2e-10 40.3 0.2 3.9e-10 39.3 0.2 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KUM64320.1 - 0.0057 16.3 0.0 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Dynamin_N PF00350.23 KUM64321.1 - 1.8e-33 115.9 0.7 3.6e-33 115.0 0.0 1.9 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KUM64321.1 - 5.2e-28 98.1 0.1 4.6e-27 95.0 0.0 2.5 1 1 1 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KUM64321.1 - 1e-05 25.6 0.1 5.2e-05 23.3 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 KUM64321.1 - 0.0014 18.7 0.0 0.0052 16.9 0.0 2.1 1 0 0 1 1 1 1 Dynamin GTPase effector domain FeoB_N PF02421.18 KUM64321.1 - 0.0015 18.1 0.1 0.049 13.2 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF572 PF04502.13 KUM64321.1 - 0.083 12.5 1.4 0.17 11.5 1.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) JIP_LZII PF16471.5 KUM64321.1 - 1.4 9.2 3.4 4 7.7 0.0 3.2 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II TMEM154 PF15102.6 KUM64322.1 - 0.059 13.3 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Stevor PF17410.2 KUM64322.1 - 0.065 12.8 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Flavin_Reduct PF01613.18 KUM64323.1 - 1.5e-15 57.5 0.0 2.2e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Putative_PNPOx PF01243.20 KUM64323.1 - 0.01 16.0 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Utp8 PF10395.9 KUM64324.1 - 1.1e-09 37.4 2.0 3.6e-09 35.7 2.0 1.8 1 1 0 1 1 1 1 Utp8 family GlutR_dimer PF00745.20 KUM64324.1 - 0.15 12.5 0.0 0.4 11.2 0.0 1.7 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain AAA PF00004.29 KUM64325.1 - 1.1e-07 32.4 0.2 6.2e-07 29.9 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KUM64325.1 - 6.1e-05 23.5 0.0 0.00016 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KUM64325.1 - 0.00058 20.4 0.0 0.0017 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KUM64325.1 - 0.001 19.4 0.0 0.0028 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KUM64325.1 - 0.0038 17.2 0.2 0.17 11.8 0.0 2.9 3 0 0 3 3 3 1 Rad17 P-loop domain T2SSE PF00437.20 KUM64325.1 - 0.0047 16.0 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Cytidylate_kin PF02224.18 KUM64325.1 - 0.023 14.4 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase TIP49 PF06068.13 KUM64325.1 - 0.029 13.6 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 KUM64325.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 KUM64325.1 - 0.079 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KUM64325.1 - 0.089 12.5 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain SBP56 PF05694.11 KUM64326.1 - 1.3e-07 30.8 0.0 8.9e-06 24.8 0.0 2.4 2 1 0 2 2 2 2 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 KUM64326.1 - 0.0095 15.2 0.2 1 8.5 0.6 2.7 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 KUM64326.1 - 0.018 14.7 0.1 5.6 6.5 0.0 3.1 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Cupin_1 PF00190.22 KUM64327.1 - 8.3e-12 45.0 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KUM64327.1 - 7e-11 41.7 0.1 9.8e-11 41.2 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_4 PF08007.12 KUM64327.1 - 0.0028 17.2 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein 3-HAO PF06052.12 KUM64327.1 - 0.018 14.7 0.0 0.04 13.6 0.0 1.5 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Fungal_trans PF04082.18 KUM64328.1 - 1.4e-24 86.6 1.5 2.6e-24 85.7 1.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KUM64328.1 - 1.4e-09 37.9 12.6 0.00025 21.3 4.0 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KUM64328.1 - 9e-07 29.1 5.8 9e-07 29.1 5.8 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KUM64328.1 - 0.0032 18.2 17.7 0.057 14.3 3.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KUM64328.1 - 0.11 12.6 3.8 0.34 11.0 3.8 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KUM64328.1 - 0.21 11.9 2.0 0.82 10.0 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KUM64328.1 - 2.4 8.4 4.5 13 6.0 4.9 2.1 2 0 0 2 2 2 0 Zinc ribbon domain ATP_synt_H PF05493.13 KUM64330.1 - 0.0072 16.8 0.3 0.012 16.1 0.0 1.5 2 0 0 2 2 2 1 ATP synthase subunit H Cys_rich_KTR PF14205.6 KUM64330.1 - 0.14 12.0 0.2 0.9 9.4 0.1 2.0 1 1 1 2 2 2 0 Cysteine-rich KTR BAR_2 PF10455.9 KUM64331.1 - 3.8e-62 210.1 3.0 5.3e-62 209.6 3.0 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KUM64331.1 - 3.9e-20 72.5 8.3 8e-19 68.2 8.3 2.0 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KUM64331.1 - 0.0015 18.2 2.7 0.013 15.3 0.2 2.4 2 0 0 2 2 2 1 BAR domain of APPL family DUF4111 PF13427.6 KUM64331.1 - 0.0096 16.1 0.2 0.061 13.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4111) ApoLp-III PF07464.11 KUM64331.1 - 0.02 15.0 3.6 0.21 11.7 0.5 2.5 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) SPATA19 PF15212.6 KUM64331.1 - 0.029 14.6 0.0 0.076 13.2 0.0 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 19, mitochondrial DUF4472 PF14739.6 KUM64331.1 - 2 9.2 6.6 1.8 9.3 0.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) Fungal_trans_2 PF11951.8 KUM64333.1 - 1.1e-19 70.5 0.0 8.5e-15 54.4 0.2 3.0 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM64333.1 - 3.2e-07 30.4 10.1 6e-07 29.5 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_8 PF05148.15 KUM64334.1 - 2.6e-54 184.4 0.0 9.1e-52 176.1 0.0 2.7 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KUM64334.1 - 4.5e-06 27.2 0.1 1.7e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM64334.1 - 0.00077 20.1 0.0 0.021 15.5 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Mucin PF01456.17 KUM64334.1 - 2 8.4 10.1 3.6 7.6 10.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Methyltransf_32 PF13679.6 KUM64334.1 - 4.3 7.3 0.0 4.3 7.3 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain GCP_N_terminal PF17681.1 KUM64335.1 - 8.1e-65 219.4 0.0 1.4e-64 218.7 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KUM64335.1 - 2.4e-59 201.3 4.0 2.4e-59 201.3 4.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal CLZ PF16526.5 KUM64335.1 - 0.12 12.7 8.4 0.04 14.3 1.7 2.9 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Methyltransf_23 PF13489.6 KUM64337.1 - 2.5e-14 53.4 0.0 3.9e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM64337.1 - 3.8e-12 46.8 0.0 1.3e-11 45.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM64337.1 - 5.9e-11 42.9 0.0 1.4e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM64337.1 - 9.2e-08 32.7 0.0 3.1e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM64337.1 - 2.5e-07 30.6 0.0 2.7e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KUM64337.1 - 5.7e-05 22.6 0.0 0.00085 18.8 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 KUM64337.1 - 0.00019 20.9 0.0 0.0022 17.4 0.0 2.5 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KUM64337.1 - 0.0056 15.3 0.0 0.036 12.6 0.0 1.9 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.19 KUM64337.1 - 0.013 15.6 0.0 0.043 13.9 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase TPMT PF05724.11 KUM64337.1 - 0.036 13.7 0.0 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_2 PF00891.18 KUM64337.1 - 0.052 12.8 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 0 O-methyltransferase domain KH_8 PF17903.1 KUM64338.1 - 2.2e-32 111.0 0.1 5.5e-32 109.7 0.1 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KUM64338.1 - 0.0012 18.6 0.0 0.0031 17.3 0.0 1.7 1 1 0 1 1 1 1 KH domain Proteasome PF00227.26 KUM64339.1 - 4.9e-58 195.8 0.1 6.1e-58 195.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KUM64339.1 - 1.7e-12 46.7 0.0 3.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Glucosamine_iso PF01182.20 KUM64341.1 - 9e-69 231.8 0.0 1e-68 231.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DAO PF01266.24 KUM64342.1 - 8.8e-32 111.0 0.1 1.2e-31 110.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KUM64342.1 - 4.3e-07 30.0 0.2 0.0083 16.1 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 KUM64342.1 - 3.7e-05 23.0 0.0 0.00017 20.8 0.0 2.0 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KUM64342.1 - 0.00095 18.5 0.0 0.81 8.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM64342.1 - 0.001 19.3 0.0 0.0033 17.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KUM64342.1 - 0.0027 16.8 0.2 0.27 10.2 0.1 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 KUM64342.1 - 0.0099 16.1 0.0 5 7.4 0.0 2.3 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain Pyr_redox_3 PF13738.6 KUM64342.1 - 0.022 14.1 0.0 3.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KUM64342.1 - 0.11 11.3 0.0 7.3 5.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase GreA_GreB_N PF03449.15 KUM64342.1 - 0.16 12.2 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Het-C PF07217.11 KUM64342.1 - 0.17 10.4 0.0 0.25 9.8 0.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Afi1 PF07792.12 KUM64344.1 - 9.8e-45 152.3 0.3 1.8e-44 151.5 0.3 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 KUM64344.1 - 1.9e-38 130.9 0.0 3e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KUM64344.1 - 8.2e-10 37.9 0.0 0.0031 16.2 0.0 4.2 3 2 2 5 5 5 3 Transport protein Avl9 DUF2347 PF09804.9 KUM64344.1 - 0.057 13.0 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) PBP1_TM PF14812.6 KUM64344.1 - 2 8.8 4.4 5.8 7.3 4.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal dUTPase PF00692.19 KUM64345.1 - 7.8e-45 151.7 0.0 9.5e-45 151.4 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 KUM64345.1 - 0.048 12.5 0.0 0.063 12.0 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Phos_pyr_kin PF08543.12 KUM64346.1 - 9.4e-13 48.1 0.0 4.7e-12 45.8 0.0 1.8 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KUM64346.1 - 7.6e-07 28.7 0.1 9.3e-06 25.1 0.0 2.3 2 0 0 2 2 2 1 pfkB family carbohydrate kinase p450 PF00067.22 KUM64347.1 - 2.9e-05 23.0 0.0 5.6e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 GH114_assoc PF14741.6 KUM64347.1 - 0.13 12.5 0.1 10 6.4 0.0 2.3 2 0 0 2 2 2 0 N-terminal glycosyl-hydrolase-114-associated domain RRM_1 PF00076.22 KUM64348.1 - 1.2e-12 47.5 0.0 3.2e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KUM64348.1 - 0.076 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_6 PF13405.6 KUM64349.1 - 8e-13 47.2 3.4 4.2e-06 26.3 0.2 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KUM64349.1 - 2e-11 42.6 1.9 1.1e-05 24.7 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KUM64349.1 - 1.1e-08 35.4 2.0 3.6e-08 33.7 0.9 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KUM64349.1 - 4.6e-06 25.9 6.4 0.014 14.8 1.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KUM64349.1 - 9.7e-06 25.3 0.7 0.016 15.0 0.0 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 KUM64349.1 - 0.0027 18.0 0.1 0.1 12.9 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain RabGAP-TBC PF00566.18 KUM64350.1 - 5.6e-28 98.1 0.0 1.1e-23 84.1 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Ribosomal_L11_N PF03946.14 KUM64351.1 - 2.4e-24 84.9 0.1 3.8e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KUM64351.1 - 1.7e-14 54.0 0.3 2.6e-14 53.5 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Glyco_transf_41 PF13844.6 KUM64352.1 - 7.5e-104 347.8 0.0 1.6e-52 178.5 0.0 3.1 1 1 2 3 3 3 3 Glycosyl transferase family 41 TPR_1 PF00515.28 KUM64352.1 - 5.6e-16 57.6 5.6 5.2e-05 22.9 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KUM64352.1 - 3.8e-15 55.3 9.9 4.8e-05 23.0 0.1 6.2 3 2 3 6 6 6 4 TPR repeat TPR_2 PF07719.17 KUM64352.1 - 6.7e-14 50.8 10.2 0.032 14.3 0.0 5.9 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 KUM64352.1 - 2.5e-12 45.9 2.9 0.00026 21.0 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KUM64352.1 - 1.7e-08 34.3 4.2 0.67 10.5 0.2 5.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KUM64352.1 - 1.3e-07 31.8 7.3 0.021 15.1 0.2 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KUM64352.1 - 1.8e-07 30.8 13.5 0.025 14.5 0.1 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KUM64352.1 - 6.1e-07 29.7 10.5 0.52 11.3 0.0 6.2 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KUM64352.1 - 1.5e-06 28.6 9.5 0.021 15.3 0.2 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KUM64352.1 - 1.2e-05 24.9 3.4 0.84 9.8 0.1 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KUM64352.1 - 0.00018 22.1 11.9 0.51 11.0 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KUM64352.1 - 0.0093 16.1 6.1 0.055 13.6 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM64352.1 - 0.037 14.3 0.7 0.29 11.4 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KUM64352.1 - 0.038 13.2 1.1 0.71 9.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KUM64352.1 - 0.079 13.4 2.8 0.75 10.2 0.0 2.8 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Myb_DNA-binding PF00249.31 KUM64353.1 - 2.6e-26 91.5 1.9 1.7e-15 57.0 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KUM64353.1 - 2e-18 66.4 2.5 3.1e-14 53.0 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.8 KUM64353.1 - 0.013 15.7 0.0 0.043 14.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Myb_DNA-bind_4 PF13837.6 KUM64353.1 - 0.077 13.4 1.1 0.31 11.5 0.1 2.2 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain LYRIC PF15686.5 KUM64354.1 - 0.008 15.8 6.5 0.0085 15.7 6.5 1.0 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family DUF4710 PF15828.5 KUM64354.1 - 0.012 15.7 6.9 0.014 15.5 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) AP3D1 PF06375.11 KUM64354.1 - 0.078 13.2 6.4 0.087 13.1 6.4 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Glyco_hydro_31 PF01055.26 KUM64355.1 - 1.1e-111 374.2 3.4 1.4e-111 373.9 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 KUM64355.1 - 7.2e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 KUM64355.1 - 0.00011 22.5 2.7 0.0015 18.8 0.2 3.0 2 1 0 2 2 2 1 Galactose mutarotase-like UPF0449 PF15136.6 KUM64355.1 - 0.048 14.1 0.0 0.53 10.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Ring_hydroxyl_A PF00848.19 KUM64356.1 - 0.093 12.7 1.6 0.16 11.9 0.5 1.8 2 0 0 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) DUF3405 PF11885.8 KUM64357.1 - 3.3e-23 82.1 0.0 3.7e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) SKG6 PF08693.10 KUM64358.1 - 3.4e-09 36.0 0.2 1.6e-08 33.8 0.2 2.2 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.6 KUM64358.1 - 0.015 15.2 0.2 0.023 14.5 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Protocadherin PF08374.11 KUM64358.1 - 0.036 14.0 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Asp_decarbox PF02261.16 KUM64358.1 - 0.045 13.7 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Aspartate decarboxylase Trp_oprn_chp PF09534.10 KUM64358.1 - 0.055 13.3 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) NCBP3 PF10309.9 KUM64359.1 - 1.9e-20 72.5 0.0 3e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 LisH PF08513.11 KUM64360.1 - 0.00068 19.5 0.1 0.0014 18.5 0.1 1.6 1 0 0 1 1 1 1 LisH ANAPC4_WD40 PF12894.7 KUM64360.1 - 0.0055 17.0 0.0 0.072 13.4 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain SET PF00856.28 KUM64361.1 - 7.3e-10 39.5 0.0 9.5e-09 35.9 0.0 2.4 2 1 0 2 2 2 1 SET domain TPR_9 PF13371.6 KUM64361.1 - 0.015 15.4 0.5 0.041 14.0 0.5 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-MYND PF01753.18 KUM64361.1 - 0.13 12.3 3.2 0.32 11.1 3.2 1.7 1 0 0 1 1 1 0 MYND finger WD40 PF00400.32 KUM64362.1 - 8.1e-23 80.3 13.5 2.4e-06 28.1 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM64362.1 - 0.0013 18.9 0.1 0.1 12.9 0.0 3.3 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DPM2 PF07297.12 KUM64367.1 - 1.5e-31 108.5 1.6 1.7e-31 108.4 1.6 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KUM64367.1 - 0.00014 21.8 0.4 0.00018 21.4 0.4 1.1 1 0 0 1 1 1 1 PIG-P DUF1772 PF08592.11 KUM64367.1 - 0.019 15.3 0.3 0.021 15.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Phage_holin_3_6 PF07332.11 KUM64367.1 - 0.036 14.1 0.6 0.043 13.9 0.6 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III LapA_dom PF06305.11 KUM64367.1 - 0.039 13.8 0.0 0.039 13.8 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MA3 PF02847.17 KUM64368.1 - 4.3e-29 100.8 0.1 9.9e-29 99.6 0.1 1.7 2 0 0 2 2 2 1 MA3 domain APH PF01636.23 KUM64369.1 - 4.6e-40 138.0 0.0 8.5e-40 137.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KUM64369.1 - 0.00022 20.6 0.0 0.00098 18.5 0.0 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 KUM64369.1 - 0.0013 18.3 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Kdo PF06293.14 KUM64369.1 - 0.0037 16.7 0.0 0.017 14.4 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 KUM64369.1 - 0.005 15.8 0.0 0.062 12.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 KUM64369.1 - 0.007 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KUM64369.1 - 0.041 13.1 0.0 1.5 8.0 0.0 2.3 1 1 0 1 1 1 0 Fructosamine kinase LPP20 PF02169.16 KUM64370.1 - 0.0047 17.3 1.5 0.0052 17.1 1.5 1.1 1 0 0 1 1 1 1 LPP20 lipoprotein Eapp_C PF10238.9 KUM64370.1 - 0.019 15.0 6.4 0.019 15.0 6.4 1.0 1 0 0 1 1 1 0 E2F-associated phosphoprotein BRF1 PF07741.13 KUM64370.1 - 0.021 15.2 10.3 0.022 15.1 10.3 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain TERB2 PF15101.6 KUM64370.1 - 0.13 12.3 3.6 0.13 12.3 3.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SUFU_C PF12470.8 KUM64370.1 - 0.14 12.2 3.7 0.15 12.1 3.7 1.0 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain EIIBC-GUT_N PF03612.14 KUM64370.1 - 0.14 11.9 4.7 0.15 11.8 4.7 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Aquarius_N PF16399.5 KUM64370.1 - 0.3 9.1 5.6 0.33 8.9 5.6 1.0 1 0 0 1 1 1 0 Intron-binding protein aquarius N-terminus SR-25 PF10500.9 KUM64370.1 - 0.3 10.7 19.5 0.32 10.6 19.5 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ALMT PF11744.8 KUM64370.1 - 0.31 9.8 3.2 0.33 9.7 3.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Connexin PF00029.19 KUM64370.1 - 0.41 10.4 6.5 0.4 10.4 6.5 1.1 1 0 0 1 1 1 0 Connexin DUF4770 PF15994.5 KUM64370.1 - 0.41 10.9 7.3 0.44 10.8 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) AP3D1 PF06375.11 KUM64370.1 - 0.45 10.7 14.8 0.52 10.5 14.8 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DDHD PF02862.17 KUM64370.1 - 0.45 10.6 3.9 0.49 10.5 3.9 1.0 1 0 0 1 1 1 0 DDHD domain DUF759 PF05537.11 KUM64370.1 - 0.45 9.3 7.5 0.54 9.1 7.5 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) Presenilin PF01080.17 KUM64370.1 - 0.47 9.2 4.5 0.48 9.1 4.5 1.0 1 0 0 1 1 1 0 Presenilin MAP17 PF15807.5 KUM64370.1 - 0.48 10.7 8.2 0.48 10.7 8.2 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EOS1 PF12326.8 KUM64370.1 - 0.56 10.1 4.4 0.62 10.0 4.4 1.1 1 0 0 1 1 1 0 N-glycosylation protein RNA_pol_Rpc4 PF05132.14 KUM64370.1 - 0.58 10.6 7.0 0.63 10.5 7.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 KUM64370.1 - 0.68 9.7 8.8 0.74 9.6 8.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.16 KUM64370.1 - 1.2 8.6 9.1 1.3 8.5 9.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Folate_carrier PF01770.18 KUM64370.1 - 1.5 7.5 3.1 1.4 7.6 3.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier PPL5 PF18168.1 KUM64370.1 - 1.5 8.0 6.0 1.6 7.9 6.0 1.0 1 0 0 1 1 1 0 Prim-pol family 5 NPR3 PF03666.13 KUM64370.1 - 2.2 7.0 9.5 2.4 6.9 9.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 OATP PF03137.20 KUM64370.1 - 2.3 6.4 4.0 2.3 6.4 4.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ATP-synt_E PF05680.12 KUM64370.1 - 3.2 8.1 11.0 3.9 7.9 11.0 1.1 1 0 0 1 1 1 0 ATP synthase E chain DUF2828 PF11443.8 KUM64370.1 - 3.6 5.6 9.6 3.8 5.5 9.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PigN PF04987.14 KUM64370.1 - 3.6 6.3 3.3 3.9 6.2 3.3 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) TMEM214 PF10151.9 KUM64370.1 - 5.8 5.2 11.3 6.6 5.1 11.3 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF3464 PF11947.8 KUM64370.1 - 7.1 6.4 11.0 8.3 6.1 11.0 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Peptidase_S49_N PF08496.10 KUM64370.1 - 8.4 6.4 13.7 10 6.2 13.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Coilin_N PF15862.5 KUM64370.1 - 8.5 6.2 16.8 11 5.8 16.8 1.2 1 0 0 1 1 1 0 Coilin N-terminus RBP_receptor PF14752.6 KUM64371.1 - 0.0075 14.9 0.5 0.01 14.5 0.5 1.1 1 0 0 1 1 1 1 Retinol binding protein receptor ATP-synt_DE_N PF02823.16 KUM64372.1 - 2.4e-17 62.6 0.0 3.7e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain PQ-loop PF04193.14 KUM64373.1 - 8.1e-33 112.0 13.3 4.9e-17 61.4 0.4 2.6 3 0 0 3 3 3 2 PQ loop repeat Cytochrom_B561 PF03188.16 KUM64374.1 - 9.6e-05 22.5 7.8 0.00024 21.3 7.5 1.8 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF202 PF02656.15 KUM64374.1 - 1.8 9.1 8.3 6.8 7.2 1.3 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF202) DUF676 PF05057.14 KUM64375.1 - 0.00083 18.9 0.3 0.0037 16.8 0.3 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KUM64375.1 - 0.0031 18.2 0.0 0.0043 17.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KUM64375.1 - 0.0041 16.9 0.1 0.0081 15.9 0.1 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KUM64375.1 - 0.025 14.2 0.2 0.063 12.9 0.2 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM64375.1 - 0.098 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FOXP-CC PF16159.5 KUM64376.1 - 0.0024 18.5 2.3 0.044 14.4 0.0 2.4 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2 PF00096.26 KUM64376.1 - 0.0029 18.0 0.1 0.0029 18.0 0.1 3.6 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM64376.1 - 0.11 13.4 0.1 0.11 13.4 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KUM64377.1 - 0.00014 22.1 9.2 0.25 11.9 0.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KUM64377.1 - 0.0032 17.8 2.1 1.4 9.4 0.2 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KUM64377.1 - 6.8 7.8 7.7 16 6.7 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Sec23_trunk PF04811.15 KUM64379.1 - 2.1e-81 273.1 0.0 3.1e-81 272.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KUM64379.1 - 9.7e-30 103.2 0.0 2e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KUM64379.1 - 1.8e-24 85.5 0.0 4.3e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KUM64379.1 - 7.5e-15 54.7 6.3 1.5e-14 53.7 6.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KUM64379.1 - 1.1e-12 47.7 0.0 2.7e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KUM64379.1 - 0.045 13.1 0.7 0.1 12.0 0.7 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Proteasome PF00227.26 KUM64380.1 - 1.3e-50 171.6 0.1 1.8e-50 171.1 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KUM64380.1 - 5.2e-13 48.4 0.3 8.3e-13 47.8 0.3 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2373 PF10180.9 KUM64381.1 - 1.1e-20 73.2 0.2 2.2e-20 72.2 0.2 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Aft1_HRA PF11786.8 KUM64383.1 - 1.7e-25 89.2 14.0 7.6e-25 87.1 9.5 3.0 2 0 0 2 2 2 1 Aft1 HRA domain Aft1_HRR PF11787.8 KUM64383.1 - 1.8e-21 77.1 6.3 1.8e-21 77.1 6.3 4.0 3 1 0 3 3 3 1 Aft1 HRR domain Aft1_OSA PF11785.8 KUM64383.1 - 3.4e-20 72.2 12.9 3.4e-20 72.2 12.9 3.9 4 0 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 KUM64383.1 - 6.9e-13 48.5 5.4 1.6e-12 47.3 5.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KUM64383.1 - 5.8e-06 26.3 6.3 1.5e-05 25.0 6.3 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KUM64383.1 - 0.0041 17.6 2.6 0.0041 17.6 2.6 2.5 3 0 0 3 3 3 1 bZIP Maf transcription factor Menin PF05053.13 KUM64383.1 - 1.7 6.9 15.6 2.4 6.4 15.6 1.2 1 0 0 1 1 1 0 Menin Macoilin PF09726.9 KUM64383.1 - 5.5 5.4 14.5 8.4 4.8 14.5 1.2 1 0 0 1 1 1 0 Macoilin family Transthyretin PF00576.21 KUM64384.1 - 2.5e-32 111.8 0.0 3.5e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 HIUase/Transthyretin family GCP_C_terminal PF04130.13 KUM64385.1 - 2.8e-103 345.6 0.1 4.3e-103 345.0 0.1 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KUM64385.1 - 1.3e-82 277.9 0.0 3.9e-82 276.3 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Fringe PF02434.16 KUM64386.1 - 7.4e-07 28.9 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 KUM64386.1 - 0.00019 21.3 0.6 0.00048 20.0 0.6 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KUM64386.1 - 0.0028 17.6 0.1 0.0061 16.5 0.1 1.5 1 0 0 1 1 1 1 PAN domain ubiquitin PF00240.23 KUM64387.1 - 5.7e-34 115.7 0.6 1e-33 114.9 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 KUM64387.1 - 1.4e-26 92.3 1.8 1.4e-26 92.3 1.8 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KUM64387.1 - 3.6e-16 58.8 0.7 6.3e-16 58.0 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KUM64387.1 - 1.8e-05 25.1 0.8 6e-05 23.4 0.3 2.0 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KUM64387.1 - 0.0014 18.7 0.7 0.003 17.6 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KUM64387.1 - 0.0052 17.1 1.1 0.0079 16.5 0.1 1.8 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KUM64387.1 - 0.0059 16.5 0.1 0.0094 15.9 0.1 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KUM64387.1 - 0.014 15.9 0.5 0.021 15.4 0.5 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KUM64387.1 - 0.03 14.4 1.0 7 6.8 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 KUM64387.1 - 0.034 14.4 0.2 0.059 13.6 0.2 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Plexin_cytopl PF08337.12 KUM64387.1 - 0.11 11.1 0.7 3.6 6.1 0.2 2.0 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain Glyco_hydro_18 PF00704.28 KUM64388.1 - 1e-88 298.1 0.2 1.2e-88 297.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 NIF PF03031.18 KUM64389.1 - 4.6e-29 101.2 0.3 1.3e-28 99.8 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KUM64389.1 - 2.5e-07 31.0 0.0 8.1e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KUM64389.1 - 0.00046 20.1 0.1 0.0011 18.8 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 KUM64389.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 KUM64389.1 - 0.019 15.4 0.1 0.82 10.1 0.0 2.6 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KUM64389.1 - 0.067 13.3 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain MARVEL PF01284.23 KUM64390.1 - 0.003 17.6 12.6 0.0048 16.9 12.6 1.3 1 1 0 1 1 1 1 Membrane-associating domain Papilloma_E5A PF05776.12 KUM64390.1 - 1.3 9.4 12.8 0.14 12.5 7.6 2.0 2 1 0 2 2 2 0 Papillomavirus E5A protein Arginase PF00491.21 KUM64391.1 - 4.4e-78 262.6 0.3 5e-78 262.4 0.3 1.0 1 0 0 1 1 1 1 Arginase family GatB_N PF02934.15 KUM64392.1 - 3.2e-97 325.2 0.0 4.4e-97 324.7 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KUM64392.1 - 5.7e-26 91.2 0.0 1.2e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 GatB domain IMUP PF15761.5 KUM64394.1 - 0.0013 19.4 6.5 0.0036 18.0 6.5 1.7 1 0 0 1 1 1 1 Immortalisation up-regulated protein FANCI_S4 PF14678.6 KUM64394.1 - 0.2 10.8 1.2 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 FANCI solenoid 4 Osw5 PF17062.5 KUM64394.1 - 0.36 10.9 2.6 0.92 9.6 2.6 1.6 1 0 0 1 1 1 0 Outer spore wall 5 ECH_1 PF00378.20 KUM64397.1 - 3.5e-42 144.4 0.0 9.8e-42 143.0 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KUM64397.1 - 7.1e-27 94.8 0.0 8.5e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Abhydrolase_6 PF12697.7 KUM64398.1 - 3.2e-06 27.9 0.0 3.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KUM64398.1 - 4e-05 23.2 0.7 0.00032 20.3 0.7 2.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KUM64398.1 - 0.0022 17.8 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KUM64398.1 - 0.023 14.5 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase YyzF PF14116.6 KUM64398.1 - 0.034 14.2 0.1 0.072 13.1 0.1 1.5 1 0 0 1 1 1 0 YyzF-like protein Hydrolase_4 PF12146.8 KUM64398.1 - 0.12 11.6 0.2 0.32 10.2 0.0 1.9 2 1 0 2 2 2 0 Serine aminopeptidase, S33 DUF155 PF02582.14 KUM64399.1 - 2.6e-47 161.2 0.0 3.9e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF2967 PF11179.8 KUM64399.1 - 0.029 12.5 0.9 0.18 9.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) Img2 PF05046.14 KUM64400.1 - 1.2e-24 86.4 0.0 1.7e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.10 KUM64401.1 - 7.4e-51 172.1 2.3 1.9e-50 170.8 2.3 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KUM64401.1 - 2.8e-14 53.5 0.0 9.9e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 PCI domain ARID PF01388.21 KUM64402.1 - 4e-19 69.1 0.0 1.4e-18 67.3 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Spond_N PF06468.13 KUM64402.1 - 0.017 15.3 3.1 0.031 14.4 3.1 1.4 1 0 0 1 1 1 0 Spondin_N DUF674 PF05056.12 KUM64402.1 - 0.1 11.5 1.0 0.13 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF674) AAA PF00004.29 KUM64403.1 - 2.1e-46 157.6 0.1 7.2e-46 155.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KUM64403.1 - 1.2e-10 41.2 0.1 7.6e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KUM64403.1 - 5e-09 36.5 0.0 1e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KUM64403.1 - 6.8e-09 35.9 0.6 2.2e-08 34.2 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KUM64403.1 - 1.9e-07 31.6 0.6 3.5e-05 24.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KUM64403.1 - 2.3e-05 24.7 1.1 0.0055 17.0 0.1 2.7 1 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 KUM64403.1 - 6.1e-05 22.3 0.0 0.00011 21.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KUM64403.1 - 0.00021 21.3 0.0 0.00074 19.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 KUM64403.1 - 0.00023 20.9 0.1 0.00055 19.7 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KUM64403.1 - 0.00031 20.5 0.0 0.001 18.9 0.0 1.9 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KUM64403.1 - 0.00059 19.4 0.0 0.0061 16.1 0.1 2.4 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 KUM64403.1 - 0.0011 19.5 0.0 0.0034 17.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 KUM64403.1 - 0.0013 18.7 0.0 0.0048 16.8 0.0 1.9 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 KUM64403.1 - 0.0015 18.9 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 KUM64403.1 - 0.0018 18.5 0.0 0.0043 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KUM64403.1 - 0.0019 17.5 0.0 0.0038 16.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 KUM64403.1 - 0.0037 17.3 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KUM64403.1 - 0.0047 16.8 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KUM64403.1 - 0.0052 16.7 0.3 0.11 12.4 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_28 PF13521.6 KUM64403.1 - 0.0075 16.5 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KUM64403.1 - 0.0078 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KUM64403.1 - 0.0085 15.8 0.2 0.2 11.3 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 KUM64403.1 - 0.0089 15.5 0.0 0.45 9.9 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 KUM64403.1 - 0.012 15.4 0.1 0.045 13.5 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 KUM64403.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KUM64403.1 - 0.013 15.3 0.1 0.033 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KUM64403.1 - 0.044 13.7 1.2 0.41 10.5 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KUM64403.1 - 0.045 13.5 0.1 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 KUM64403.1 - 0.064 12.1 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase Bac_DnaA PF00308.18 KUM64403.1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.6 KUM64403.1 - 0.067 12.8 1.1 0.22 11.1 0.4 2.2 2 1 1 3 3 3 0 AAA domain ATPase PF06745.13 KUM64403.1 - 0.077 12.3 0.9 0.91 8.8 0.0 2.4 3 0 0 3 3 2 0 KaiC Zeta_toxin PF06414.12 KUM64403.1 - 0.083 12.2 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 KUM64403.1 - 0.086 13.3 0.2 2.3 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KUM64403.1 - 0.13 12.6 0.1 0.4 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KUM64403.1 - 0.15 12.6 0.1 0.57 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KUM64403.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_Hsp90 PF03225.14 KUM64403.1 - 0.17 10.3 0.0 0.27 9.7 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Parvo_NS1 PF01057.17 KUM64403.1 - 0.2 10.7 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Asp PF00026.23 KUM64405.1 - 4e-109 364.8 0.1 4.8e-109 364.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KUM64405.1 - 7.1e-17 62.2 1.6 1.1e-14 55.1 1.3 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KUM64405.1 - 3.6e-05 24.3 0.2 0.24 12.1 0.0 3.4 2 2 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KUM64405.1 - 0.00025 21.5 0.0 1.1 9.8 0.0 3.5 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KUM64405.1 - 0.01 15.6 0.0 0.16 11.8 0.0 2.4 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Peptidase_M20 PF01546.28 KUM64406.1 - 2.8e-14 53.3 0.0 5e-14 52.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KUM64406.1 - 1.2e-08 34.8 0.0 2.5e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain ArsA_ATPase PF02374.15 KUM64408.1 - 2.3e-114 381.7 0.1 2.7e-114 381.5 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KUM64408.1 - 1e-13 51.6 0.1 5.4e-13 49.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 KUM64408.1 - 3.5e-13 49.7 0.0 7.7e-13 48.6 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 KUM64408.1 - 2.2e-06 27.3 0.0 5.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 KUM64408.1 - 2e-05 24.1 2.7 0.00013 21.5 0.1 2.5 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 KUM64408.1 - 2.9e-05 23.8 1.1 0.00083 19.0 0.1 2.8 3 1 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 KUM64408.1 - 8.6e-05 22.1 0.1 0.00029 20.4 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ PhoH PF02562.16 KUM64408.1 - 0.014 14.8 0.0 0.044 13.2 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 KUM64408.1 - 0.039 13.5 0.0 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain A1_Propeptide PF07966.12 KUM64408.1 - 0.1 12.5 2.1 0.13 12.2 0.1 2.3 2 0 0 2 2 2 0 A1 Propeptide Ribonuclease_T2 PF00445.18 KUM64409.1 - 8.7e-44 149.9 0.1 1.7e-43 149.0 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family zf-H2C2_2 PF13465.6 KUM64410.1 - 2.7e-08 33.8 3.6 0.0046 17.3 0.6 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KUM64410.1 - 5.1e-07 29.8 14.7 0.0036 17.7 4.5 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KUM64410.1 - 5.2e-06 26.3 4.8 0.019 14.9 3.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KUM64410.1 - 1e-05 25.9 15.5 0.0028 18.4 3.6 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KUM64410.1 - 0.0035 17.6 2.3 0.0035 17.6 2.3 2.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KUM64410.1 - 0.57 10.7 3.2 1.7 9.2 3.2 1.8 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 KUM64410.1 - 1.5 8.9 5.1 0.9 9.6 2.1 2.1 1 1 1 2 2 2 0 BED zinc finger Metallopep PF12044.8 KUM64411.1 - 1.6e-175 583.8 0.0 2e-175 583.5 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.6 KUM64411.1 - 0.042 14.0 0.4 0.075 13.2 0.4 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KUM64411.1 - 0.13 12.8 0.7 0.27 11.7 0.7 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CP2 PF04516.15 KUM64412.1 - 4.7e-81 271.5 0.0 7.2e-81 270.8 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Abhydrolase_6 PF12697.7 KUM64413.1 - 2.9e-10 41.1 0.0 3.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM64413.1 - 7.3e-09 35.2 0.0 6.4e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KUM64413.1 - 8.3e-09 35.5 0.0 4.2e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 KUM64413.1 - 1.8e-05 24.7 0.0 0.00039 20.4 0.0 2.2 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 KUM64413.1 - 2.8e-05 24.1 0.0 6.6e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KUM64413.1 - 0.00077 19.0 0.0 0.2 11.1 0.0 2.3 1 1 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 KUM64413.1 - 0.0012 18.5 0.0 0.037 13.7 0.0 2.2 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Palm_thioest PF02089.15 KUM64413.1 - 0.0038 17.1 0.0 0.0056 16.6 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Thioesterase PF00975.20 KUM64413.1 - 0.093 12.8 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 KUM64413.1 - 0.17 11.5 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Clathrin PF00637.20 KUM64415.1 - 3.5e-19 69.1 0.0 9.8e-19 67.6 0.0 1.8 1 0 0 1 1 1 1 Region in Clathrin and VPS HicB_lk_antitox PF15919.5 KUM64415.1 - 0.081 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system WD40_like PF17005.5 KUM64415.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain Vps39_1 PF10366.9 KUM64415.1 - 0.089 13.1 0.1 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Tub_N PF16322.5 KUM64415.1 - 0.13 12.7 8.5 0.064 13.7 5.7 1.9 2 0 0 2 2 2 0 Tubby N-terminal zf-RING_5 PF14634.6 KUM64415.1 - 0.26 11.3 0.3 0.52 10.3 0.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain FAM176 PF14851.6 KUM64415.1 - 1.3 8.7 3.9 2.9 7.5 3.9 1.5 1 0 0 1 1 1 0 FAM176 family Anophelin PF10731.9 KUM64415.1 - 1.5 8.7 4.3 5 7.0 4.3 1.9 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Oxidored_FMN PF00724.20 KUM64416.1 - 2e-60 204.9 0.0 2.6e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 KUM64416.1 - 1.6e-05 24.5 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 KUM64416.1 - 0.00097 18.3 0.8 0.0012 18.0 0.0 1.5 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KUM64416.1 - 0.003 16.8 0.1 0.0057 15.9 0.1 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KUM64416.1 - 0.0032 16.5 0.2 0.008 15.2 0.1 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase PcrB PF01884.17 KUM64416.1 - 0.021 14.3 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 PcrB family IMPDH PF00478.25 KUM64416.1 - 0.034 13.1 0.2 0.12 11.3 0.1 1.8 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain RNA_pol_Rpo13 PF12136.8 KUM64416.1 - 0.07 13.1 0.4 0.15 12.0 0.1 1.6 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain G3P_antiterm PF04309.12 KUM64416.1 - 0.17 11.3 0.1 0.51 9.7 0.1 1.8 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator NB-ARC PF00931.22 KUM64417.1 - 3.1e-11 43.0 0.0 4.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KUM64417.1 - 9.1e-06 26.2 0.0 1.9e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 KUM64417.1 - 0.0023 17.3 0.0 0.0055 16.1 0.0 1.5 2 0 0 2 2 2 1 KaiC NACHT PF05729.12 KUM64417.1 - 0.0034 17.3 0.2 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.12 KUM64417.1 - 0.013 14.8 0.0 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 KUM64417.1 - 0.016 15.4 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KUM64417.1 - 0.063 13.4 0.1 0.16 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KUM64417.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 KUM64417.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DIOX_N PF14226.6 KUM64419.1 - 6.2e-27 94.7 0.1 9.8e-27 94.1 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KUM64419.1 - 9.4e-19 67.8 0.0 2.4e-18 66.4 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.15 KUM64420.1 - 4.3e-102 342.2 29.1 5e-102 341.9 29.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ADC PF06314.11 KUM64421.1 - 6.6e-44 150.2 0.0 8.3e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) AA_permease PF00324.21 KUM64422.1 - 1.3e-103 347.2 36.9 1.6e-103 346.9 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM64422.1 - 1.3e-28 100.0 40.2 1.7e-28 99.7 40.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1612 PF07756.12 KUM64422.1 - 0.03 14.6 1.8 0.36 11.1 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) DUF1749 PF08538.10 KUM64423.1 - 6.1e-96 321.0 0.0 7.5e-96 320.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KUM64423.1 - 2.6e-05 24.9 0.3 3.6e-05 24.5 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM64423.1 - 0.16 11.2 0.1 0.73 9.0 0.1 2.1 2 1 0 2 2 2 0 Serine aminopeptidase, S33 DUF2164 PF09932.9 KUM64423.1 - 0.18 11.9 0.2 0.37 10.9 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) Exo_endo_phos PF03372.23 KUM64424.1 - 8.9e-12 45.0 1.0 2.6e-11 43.5 1.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KUM64424.1 - 0.0086 15.9 0.1 0.03 14.2 0.1 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase BACON PF13004.7 KUM64424.1 - 0.044 13.8 1.2 0.21 11.6 1.0 2.1 2 0 0 2 2 2 0 Putative binding domain, N-terminal COesterase PF00135.28 KUM64425.1 - 3e-63 214.5 0.0 6.5e-62 210.0 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family F-box-like PF12937.7 KUM64426.1 - 1.8e-07 30.9 1.4 4.8e-06 26.4 0.1 2.7 2 0 0 2 2 2 2 F-box-like Ras PF00071.22 KUM64428.1 - 1.2e-51 174.5 0.7 7.1e-51 172.0 0.7 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KUM64428.1 - 1.4e-18 67.2 0.1 1.9e-17 63.6 0.1 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM64428.1 - 0.00053 19.5 0.1 0.0041 16.6 0.1 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.18 KUM64428.1 - 0.011 15.3 0.3 0.23 11.0 0.0 2.5 2 1 1 3 3 3 0 Ferrous iron transport protein B SRPRB PF09439.10 KUM64428.1 - 0.027 13.9 0.1 0.68 9.3 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KUM64428.1 - 0.11 12.4 0.0 9.1 6.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 KUM64428.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_25 PF13481.6 KUM64428.1 - 0.13 11.8 0.1 0.33 10.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KUM64428.1 - 0.14 11.6 0.0 6.5 6.2 0.0 2.7 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain AMP-binding PF00501.28 KUM64429.1 - 1.9e-76 257.4 0.0 2.5e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KUM64429.1 - 3.9e-16 58.7 0.2 1.2e-15 57.1 0.2 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KUM64429.1 - 6.4e-15 55.9 0.0 2.6e-14 53.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 KUM64430.1 - 4.5e-34 118.0 0.0 1.7e-16 60.4 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KUM64430.1 - 9.8e-12 44.7 0.0 8.3e-06 25.3 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase HNH_2 PF13391.6 KUM64431.1 - 0.067 13.3 0.5 0.19 11.9 0.5 1.8 1 0 0 1 1 1 0 HNH endonuclease Cyclin PF08613.11 KUM64432.1 - 3e-34 118.7 0.0 3.8e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KUM64432.1 - 0.0021 17.8 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF1731 PF08338.11 KUM64432.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) hDGE_amylase PF14701.6 KUM64433.1 - 0.45 9.6 3.3 0.54 9.3 2.3 1.6 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain PALP PF00291.25 KUM64434.1 - 1.9e-65 221.2 0.0 2.5e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KUM64434.1 - 5.4e-12 46.0 0.4 8.1e-08 32.6 0.0 3.1 4 0 0 4 4 4 2 CBS domain Na_Ca_ex PF01699.24 KUM64435.1 - 1.5e-24 86.7 30.1 1.7e-14 54.1 10.0 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3185 PF11381.8 KUM64435.1 - 0.011 15.7 0.1 1.4 8.9 0.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3185) DUF2290 PF10053.9 KUM64435.1 - 0.03 13.8 0.1 0.053 13.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2290) MSP1a PF11670.8 KUM64435.1 - 0.033 13.5 0.5 0.075 12.3 0.5 1.6 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) DUF202 PF02656.15 KUM64435.1 - 0.049 14.1 9.0 9.7 6.7 0.2 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF202) Formyl_trans_N PF00551.19 KUM64435.1 - 0.052 13.3 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Formyl transferase Archease PF01951.16 KUM64435.1 - 0.054 13.7 0.1 0.093 13.0 0.1 1.4 1 0 0 1 1 1 0 Archease protein family (MTH1598/TM1083) PhoQ_Sensor PF08918.10 KUM64435.1 - 0.06 13.2 0.3 0.16 11.8 0.1 1.9 1 1 1 2 2 2 0 PhoQ Sensor GPI-anchored PF10342.9 KUM64436.1 - 1.4e-06 28.9 0.2 1.4e-06 28.9 0.2 2.1 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.11 KUM64436.1 - 3.3e-05 24.6 6.1 3.3e-05 24.6 6.1 2.4 2 1 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 SRPRB PF09439.10 KUM64437.1 - 2.4e-23 82.5 3.2 9.5e-22 77.3 3.2 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KUM64437.1 - 0.00012 22.2 0.1 0.00021 21.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KUM64437.1 - 0.00028 20.4 0.1 0.0044 16.5 0.0 2.3 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_29 PF13555.6 KUM64437.1 - 0.0072 16.1 0.8 0.017 14.9 0.2 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KUM64437.1 - 0.0081 16.6 0.4 0.019 15.3 0.2 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KUM64437.1 - 0.017 15.4 0.3 0.047 14.0 0.3 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KUM64437.1 - 0.02 14.6 0.0 0.91 9.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain ATP_bind_1 PF03029.17 KUM64437.1 - 0.033 14.0 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KUM64437.1 - 0.056 13.4 0.8 0.4 10.6 0.3 2.2 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KUM64437.1 - 0.06 13.9 0.1 0.13 12.8 0.1 1.8 1 1 0 1 1 1 0 ABC transporter Peptidase_M76 PF09768.9 KUM64438.1 - 2.2e-74 248.9 2.0 2.6e-74 248.6 2.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family HNH_5 PF14279.6 KUM64438.1 - 0.018 14.9 0.6 0.18 11.7 0.1 2.4 2 0 0 2 2 2 0 HNH endonuclease SprT-like PF10263.9 KUM64438.1 - 0.5 10.2 3.5 0.39 10.6 1.4 1.8 1 1 1 2 2 2 0 SprT-like family AA_kinase PF00696.28 KUM64439.1 - 3.6e-39 134.8 0.6 6.3e-39 134.0 0.6 1.4 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KUM64439.1 - 5.1e-16 58.4 0.0 6.2e-15 54.9 0.0 2.3 2 0 0 2 2 2 1 PUA domain Pkinase PF00069.25 KUM64441.1 - 6.4e-65 219.1 0.0 9.6e-65 218.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM64441.1 - 6.2e-42 143.7 0.0 8.3e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM64441.1 - 3.4e-08 33.2 0.0 1.5e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KUM64441.1 - 6.7e-05 22.3 0.2 0.00012 21.5 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KUM64441.1 - 0.0036 16.3 0.8 0.0044 16.0 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 KUM64441.1 - 0.041 13.5 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KUM64441.1 - 0.056 13.4 0.1 0.076 12.9 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KUM64441.1 - 0.072 12.7 0.0 0.18 11.4 0.0 1.6 1 1 1 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.9 KUM64441.1 - 0.11 11.9 0.1 0.25 10.9 0.1 1.7 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Transferase PF02458.15 KUM64444.1 - 5.4e-14 51.7 0.0 3.9e-11 42.3 0.0 2.5 3 0 0 3 3 3 2 Transferase family HeH PF12949.7 KUM64445.1 - 0.02 14.6 0.0 0.36 10.6 0.0 2.4 2 0 0 2 2 2 0 HeH/LEM domain DUF4246 PF14033.6 KUM64447.1 - 2.3e-164 547.8 0.1 2.7e-164 547.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Med4 PF10018.9 KUM64448.1 - 0.51 10.0 4.0 2.3 7.9 0.1 2.6 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Cyt-b5 PF00173.28 KUM64449.1 - 1.3e-21 76.5 0.1 1.5e-21 76.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 KUM64449.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.4 1 1 0 1 1 1 0 V-ATPase subunit H OB_NTP_bind PF07717.16 KUM64450.1 - 7e-22 77.6 0.0 1.9e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KUM64450.1 - 1.6e-19 70.2 0.0 1.6e-19 70.2 0.0 3.6 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KUM64450.1 - 5.4e-13 49.3 0.0 1.2e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KUM64450.1 - 6.2e-07 29.4 0.2 2.4e-06 27.4 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KUM64450.1 - 5e-05 23.1 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KUM64450.1 - 7e-05 22.0 0.0 0.00016 20.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KUM64450.1 - 8.6e-05 22.8 0.5 0.00059 20.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KUM64450.1 - 0.00014 22.2 0.1 0.00034 21.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 KUM64450.1 - 0.02 14.2 0.5 1.2 8.5 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 KUM64450.1 - 0.029 14.9 0.0 0.029 14.9 0.0 3.7 1 1 1 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.6 KUM64450.1 - 0.038 14.1 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain SRP54 PF00448.22 KUM64450.1 - 0.078 12.6 0.1 0.18 11.4 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 KUM64450.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain HAD_2 PF13419.6 KUM64451.1 - 3e-07 30.7 0.0 4.9e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KUM64451.1 - 0.00017 21.6 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KUM64451.1 - 0.00092 19.6 0.0 0.0015 18.9 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mcp5_PH PF12814.7 KUM64452.1 - 2.9e-45 153.3 0.0 5.8e-45 152.4 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.12 KUM64452.1 - 9e-05 22.5 17.0 0.0024 18.0 8.5 2.4 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein APH PF01636.23 KUM64452.1 - 0.084 12.8 0.6 0.16 11.8 0.6 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family GAS PF13851.6 KUM64452.1 - 0.085 12.2 14.6 2.7 7.3 14.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KUM64452.1 - 0.23 11.9 16.5 0.081 13.4 13.4 1.7 1 1 1 2 2 2 0 Fez1 Fib_alpha PF08702.10 KUM64452.1 - 0.28 11.4 1.7 2.3 8.4 0.9 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 KUM64452.1 - 0.75 9.2 12.5 1.3 8.5 12.5 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 UPF0242 PF06785.11 KUM64452.1 - 1 9.5 6.9 2.4 8.2 6.9 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 KUM64452.1 - 2.6 7.8 8.9 2 8.2 7.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.15 KUM64452.1 - 2.6 7.9 5.4 5.5 6.8 0.1 3.5 2 2 2 4 4 4 0 Septum formation initiator ZapB PF06005.12 KUM64452.1 - 2.9 8.4 14.1 1.8 9.1 0.9 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Condensation PF00668.20 KUM64453.1 - 5e-209 694.7 0.0 6.3e-42 143.8 0.0 6.4 6 0 0 6 6 6 6 Condensation domain AMP-binding PF00501.28 KUM64453.1 - 5.8e-187 621.5 0.0 9.3e-85 284.7 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme PP-binding PF00550.25 KUM64453.1 - 2.1e-50 168.9 12.8 1.4e-11 44.6 0.0 6.8 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM64453.1 - 3.7e-10 40.6 0.0 0.00017 22.5 0.0 4.0 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 KUM64453.1 - 8.6e-06 25.7 0.0 2.9 7.6 0.0 4.3 4 0 0 4 4 4 3 Wax ester synthase-like Acyl-CoA acyltransferase domain Transferase PF02458.15 KUM64453.1 - 0.017 13.8 0.1 7.1 5.1 0.0 4.8 7 0 0 7 7 7 0 Transferase family FYDLN_acid PF09538.10 KUM64454.1 - 1.7 9.4 7.9 1.4 9.7 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Pkinase PF00069.25 KUM64455.1 - 1.5e-39 136.0 0.0 3.3e-38 131.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM64455.1 - 3.8e-23 82.1 0.0 7.3e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase K_oxygenase PF13434.6 KUM64456.1 - 3.3e-111 371.7 0.0 5.1e-111 371.1 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KUM64456.1 - 5.2e-06 25.9 0.1 0.0016 17.8 0.0 2.8 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM64456.1 - 1.8e-05 24.1 0.0 0.00092 18.5 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DHHC PF01529.20 KUM64457.1 - 3.3e-35 121.1 7.8 3.3e-35 121.1 7.8 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KUM64457.1 - 2.4e-27 95.3 0.1 1e-12 48.5 0.0 3.9 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KUM64457.1 - 7.1e-25 86.8 3.7 9.2e-07 29.0 0.0 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM64457.1 - 4.6e-21 72.7 1.7 3.3e-07 30.1 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 KUM64457.1 - 1.9e-18 66.0 0.8 2.1e-06 27.9 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KUM64457.1 - 1.4e-17 63.8 0.7 2.1e-06 28.2 0.3 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) DUF1430 PF07242.11 KUM64457.1 - 0.043 14.1 0.9 0.043 14.1 0.9 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1430) Toxin_5 PF05294.13 KUM64457.1 - 3.5 8.1 6.3 7.6 7.1 6.3 1.6 1 0 0 1 1 1 0 Scorpion short toxin TIP41 PF04176.13 KUM64458.1 - 1.5e-70 236.1 0.0 1.8e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Ubiq_cyt_C_chap PF03981.12 KUM64459.1 - 8.8e-37 126.3 0.2 4.7e-36 124.0 0.1 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone MAAL_N PF05034.13 KUM64459.1 - 0.057 13.1 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase N-terminus Peptidase_M1 PF01433.20 KUM64460.1 - 1.2e-46 159.0 0.4 1.7e-46 158.5 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KUM64460.1 - 1.8e-29 103.3 0.0 2.6e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Leuk-A4-hydro_C PF09127.11 KUM64460.1 - 3.9e-17 62.4 0.0 7.9e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M61 PF05299.12 KUM64460.1 - 0.13 12.6 2.8 3 8.3 2.0 3.0 2 1 0 2 2 2 0 M61 glycyl aminopeptidase MIT PF04212.18 KUM64461.1 - 3.7e-12 46.1 0.4 3.7e-12 46.1 0.4 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain DUF4778 PF16008.5 KUM64461.1 - 0.056 13.5 0.9 0.097 12.7 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Eaf7 PF07904.13 KUM64462.1 - 1.1e-28 99.6 0.0 2.6e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 NOA36 PF06524.12 KUM64462.1 - 1.8 7.8 4.0 3.3 6.9 4.0 1.4 1 0 0 1 1 1 0 NOA36 protein GCP_C_terminal PF04130.13 KUM64463.1 - 2.5e-67 227.5 0.0 3.7e-67 227.0 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KUM64463.1 - 3.7e-56 191.0 0.4 9.8e-56 189.6 0.2 1.8 3 0 0 3 3 3 1 Gamma tubulin complex component N-terminal Rieske_2 PF13806.6 KUM64464.1 - 3.1e-17 62.4 0.0 4.9e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 KUM64464.1 - 1.3e-14 53.9 0.0 2.2e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain MFS_1 PF07690.16 KUM64465.1 - 1.5e-29 103.1 42.4 1.7e-28 99.6 22.9 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Mo-co_dimer PF03404.16 KUM64466.1 - 2.8e-58 195.8 0.1 5.5e-58 194.9 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 KUM64466.1 - 2.1e-51 173.9 0.0 3.7e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 KUM64466.1 - 2.1e-35 121.0 0.0 3.5e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KUM64466.1 - 2.3e-31 108.7 0.0 4.5e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KUM64466.1 - 2.2e-16 59.8 0.0 4e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KUM64466.1 - 0.0027 17.8 0.0 0.7 10.0 0.0 2.4 1 1 0 2 2 2 2 Ferric reductase NAD binding domain Pyr_redox_2 PF07992.14 KUM64467.1 - 6.1e-44 150.4 1.7 7e-44 150.2 0.9 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM64467.1 - 2.3e-15 56.9 7.2 1.3e-14 54.5 0.6 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 KUM64467.1 - 2.4e-14 53.4 10.2 2.5e-12 46.9 6.4 3.1 3 0 0 3 3 3 2 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 KUM64467.1 - 4.6e-11 42.4 0.0 1.1e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain NIR_SIR PF01077.22 KUM64467.1 - 3.3e-07 29.9 0.0 1.3e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain Rubredoxin_C PF18267.1 KUM64467.1 - 6.1e-07 29.3 0.2 0.012 15.5 0.0 3.4 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 KUM64467.1 - 0.00036 20.6 0.9 1.8 8.5 0.0 3.4 3 1 1 4 4 4 2 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KUM64467.1 - 0.032 13.5 1.4 2.1 7.5 0.0 2.2 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KUM64467.1 - 0.041 12.9 0.0 0.041 12.9 0.0 2.1 2 1 0 2 2 2 0 FAD binding domain DAO PF01266.24 KUM64467.1 - 0.098 12.2 0.2 0.79 9.2 0.0 2.4 2 1 1 3 3 3 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KUM64467.1 - 0.16 12.4 0.2 2.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding adh_short_C2 PF13561.6 KUM64468.1 - 1.1e-47 162.6 0.2 1.3e-47 162.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM64468.1 - 2.3e-42 144.7 0.2 2.7e-42 144.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM64468.1 - 5.2e-13 49.3 0.2 8e-13 48.7 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM64468.1 - 1.2e-07 31.5 0.1 5.3e-07 29.3 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KUM64468.1 - 6.1e-05 22.5 0.0 9.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KUM64468.1 - 0.1 12.5 0.3 14 5.5 0.1 2.8 3 0 0 3 3 3 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KUM64468.1 - 0.14 11.2 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein rhaM PF05336.13 KUM64470.1 - 3.3e-37 126.9 0.1 3.7e-37 126.7 0.1 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase SLC12 PF03522.15 KUM64471.1 - 0.87 8.5 6.9 1 8.3 1.6 2.3 2 0 0 2 2 2 0 Solute carrier family 12 DUF4131 PF13567.6 KUM64471.1 - 3.1 7.4 4.5 1.5 8.4 0.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) IU_nuc_hydro PF01156.19 KUM64472.1 - 4.2e-56 190.8 0.0 7.4e-56 189.9 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Transketolase_C PF02780.20 KUM64472.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Transketolase, C-terminal domain Fungal_trans PF04082.18 KUM64474.1 - 4.7e-13 48.8 0.1 6.6e-13 48.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HLH PF00010.26 KUM64476.1 - 8.1e-14 51.3 0.1 2.2e-13 49.9 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MFS_1 PF07690.16 KUM64477.1 - 7.1e-40 137.0 31.0 7.1e-40 137.0 31.0 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM64477.1 - 2.5e-12 46.4 5.6 2.5e-12 46.4 5.6 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter ABC_membrane_2 PF06472.15 KUM64481.1 - 4.9e-87 291.7 2.7 1.2e-77 260.9 0.6 2.3 1 1 1 2 2 2 2 ABC transporter transmembrane region 2 HAD PF12710.7 KUM64481.1 - 1.2e-28 100.9 0.0 2.7e-28 99.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ABC_tran PF00005.27 KUM64481.1 - 9.3e-19 68.3 0.0 1.8e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KUM64481.1 - 0.00014 21.8 0.0 0.00036 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KUM64481.1 - 0.0064 17.0 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KUM64481.1 - 0.033 13.9 0.0 0.089 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Put_Phosphatase PF06888.12 KUM64481.1 - 0.045 13.2 0.0 3.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Putative Phosphatase Reticulon PF02453.17 KUM64481.1 - 0.052 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Reticulon SMC_N PF02463.19 KUM64481.1 - 0.054 12.9 0.1 0.21 11.0 0.1 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Hydrolase PF00702.26 KUM64481.1 - 0.076 13.3 0.0 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RuvB_N PF05496.12 KUM64481.1 - 0.096 12.4 0.0 2.2 8.0 0.0 2.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KUM64481.1 - 0.17 11.8 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 KUM64481.1 - 0.36 11.2 1.2 1.4 9.3 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain adh_short PF00106.25 KUM64482.1 - 6.4e-21 74.7 0.0 1.6e-19 70.1 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM64482.1 - 1.5e-10 41.0 0.0 9.2e-10 38.5 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KUM64482.1 - 0.0015 17.7 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KUM64482.1 - 0.0057 16.6 0.0 0.0078 16.1 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF2436 PF10365.9 KUM64482.1 - 0.081 12.7 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) LRR_4 PF12799.7 KUM64483.1 - 0.01 16.2 2.8 4.6 7.8 0.0 5.5 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Ribosomal_L5e PF17144.4 KUM64486.1 - 2e-82 275.0 0.5 3.4e-82 274.3 0.5 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KUM64486.1 - 1.7e-32 112.2 9.9 1.7e-32 112.2 9.9 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region HAD_2 PF13419.6 KUM64486.1 - 2.8e-06 27.5 1.1 1.6e-05 25.1 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KUM64486.1 - 0.004 17.5 0.1 0.015 15.6 0.0 1.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Abhydrolase_1 PF00561.20 KUM64489.1 - 9.3e-21 74.6 0.8 2.9e-20 73.0 0.8 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KUM64489.1 - 3.8e-16 60.4 1.4 5.2e-16 59.9 1.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM64489.1 - 6.5e-16 58.3 0.1 1.2e-15 57.4 0.1 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KUM64489.1 - 2.8e-05 23.0 0.0 3.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 KUM64489.1 - 0.00021 21.1 0.0 0.00072 19.4 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KUM64489.1 - 0.00038 20.2 0.0 0.00058 19.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.11 KUM64489.1 - 0.0011 18.3 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Say1_Mug180 PF10340.9 KUM64489.1 - 0.0045 15.9 0.0 0.0063 15.4 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Eno-Rase_NADH_b PF12242.8 KUM64489.1 - 0.0099 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Esterase PF00756.20 KUM64489.1 - 0.02 14.6 0.0 0.074 12.7 0.0 1.9 2 0 0 2 2 2 0 Putative esterase UPF0227 PF05728.12 KUM64489.1 - 0.031 14.2 0.1 0.047 13.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Chlorophyllase2 PF12740.7 KUM64489.1 - 0.042 12.7 0.0 0.097 11.6 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 KUM64489.1 - 0.11 11.5 0.1 0.37 9.8 0.1 1.7 1 1 0 1 1 1 0 Chlorophyllase Abhydrolase_3 PF07859.13 KUM64489.1 - 0.13 12.1 0.3 0.37 10.6 0.0 1.9 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF3530 PF12048.8 KUM64489.1 - 0.15 11.5 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) PAF-AH_p_II PF03403.13 KUM64489.1 - 0.21 10.1 0.0 0.28 9.6 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II BSP PF04450.12 KUM64490.1 - 8.8e-76 254.3 0.0 1.1e-75 254.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Ribonucleas_3_3 PF14622.6 KUM64493.1 - 7.7e-06 26.1 0.0 0.00062 19.9 0.1 2.3 2 0 0 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KUM64493.1 - 1.7e-05 25.4 0.0 0.00012 22.7 0.0 2.2 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 KUM64493.1 - 0.0012 19.5 0.5 0.004 17.8 0.0 2.2 3 0 0 3 3 3 1 Double-stranded RNA binding motif CAP_N PF01213.19 KUM64494.1 - 2.8e-111 372.0 9.5 1.2e-108 363.4 9.5 2.4 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KUM64494.1 - 2.4e-58 196.2 0.4 3.2e-58 195.8 0.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KUM64494.1 - 0.21 11.3 4.2 6.1 6.6 2.6 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor C PfkB PF00294.24 KUM64495.1 - 2.3e-10 40.3 0.0 3.9e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase rRNA_processing PF08524.11 KUM64496.1 - 0.034 14.2 21.2 0.19 11.7 21.2 1.9 1 1 0 1 1 1 0 rRNA processing DUF334 PF03904.13 KUM64496.1 - 0.05 13.1 0.1 0.086 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Trypan_PARP PF05887.11 KUM64496.1 - 0.91 9.5 8.7 1.5 8.8 8.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RR_TM4-6 PF06459.12 KUM64496.1 - 7.5 6.3 8.2 9.7 5.9 8.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4210 PF13915.6 KUM64497.1 - 1.3e-31 109.0 1.1 2.4e-31 108.1 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 KUM64497.1 - 2.4e-23 82.0 0.3 5.4e-23 80.9 0.3 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis Iso_dh PF00180.20 KUM64498.1 - 9.2e-102 340.7 0.0 1.1e-101 340.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.7 KUM64498.1 - 0.033 14.3 0.1 0.95 9.6 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sec5 PF15469.6 KUM64499.1 - 6.2e-36 124.0 0.0 1.6e-35 122.7 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 KUM64499.1 - 2.5e-05 24.3 0.2 0.0001 22.3 0.0 2.2 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 KUM64499.1 - 0.093 12.8 0.0 0.37 10.9 0.0 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-R PF06729.12 KUM64499.1 - 0.11 12.4 0.1 0.39 10.6 0.1 2.0 1 0 0 1 1 1 0 Kinetochore component, CENP-R FMO-like PF00743.19 KUM64502.1 - 2.6e-24 85.6 0.0 7.7e-24 84.0 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KUM64502.1 - 7e-22 78.0 0.0 6.7e-21 74.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM64502.1 - 4.8e-14 52.3 0.0 1.7e-11 43.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM64502.1 - 2.3e-10 40.2 0.2 5.1e-08 32.4 0.0 3.1 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KUM64502.1 - 9.8e-08 31.6 1.1 0.00065 19.0 0.3 3.1 2 1 1 3 3 3 2 FAD binding domain 2-Hacid_dh_C PF02826.19 KUM64502.1 - 3.6e-06 26.5 0.3 0.03 13.7 0.1 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KUM64502.1 - 6e-06 26.4 0.0 0.00036 20.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KUM64502.1 - 7.1e-06 26.5 0.1 0.1 13.2 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM64502.1 - 0.00018 21.5 0.1 0.93 9.5 0.0 3.4 2 1 1 3 3 3 1 FAD-NAD(P)-binding IlvN PF07991.12 KUM64502.1 - 0.00037 20.1 0.0 0.0021 17.6 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Lycopene_cycl PF05834.12 KUM64502.1 - 0.00079 18.6 0.1 0.044 12.8 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KUM64502.1 - 0.0015 17.7 0.2 0.014 14.5 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 KUM64502.1 - 0.0022 17.9 0.1 0.087 12.7 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KUM64502.1 - 0.0027 17.9 0.1 0.53 10.6 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_2 PF03446.15 KUM64502.1 - 0.0044 17.2 0.5 2 8.5 0.4 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.14 KUM64502.1 - 0.0069 15.1 0.1 0.46 9.1 0.0 2.5 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_7 PF13241.6 KUM64502.1 - 0.0087 16.5 0.0 0.2 12.1 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KUM64502.1 - 0.021 14.9 0.0 0.51 10.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KUM64502.1 - 0.029 13.5 0.1 8.1 5.4 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KUM64502.1 - 0.036 13.3 0.1 5.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KUM64502.1 - 0.1 12.2 0.0 14 5.3 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KUM64502.1 - 0.19 12.3 0.0 16 6.2 0.0 3.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent APH PF01636.23 KUM64503.1 - 9.3e-17 61.7 0.0 1.3e-14 54.7 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KUM64503.1 - 0.00085 19.0 0.0 0.0022 17.6 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF4408 PF14364.6 KUM64504.1 - 0.024 14.4 0.7 0.1 12.4 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4408) Transferase PF02458.15 KUM64505.1 - 0.021 13.5 0.0 1.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Transferase family GFO_IDH_MocA PF01408.22 KUM64506.1 - 4.8e-13 50.0 0.0 7.8e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CLASP_N PF12348.8 KUM64508.1 - 2e-146 485.5 0.0 1.3e-86 289.9 0.0 2.3 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 KUM64508.1 - 1.2e-08 34.4 0.1 0.11 12.9 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 KUM64508.1 - 4.3e-07 30.1 0.1 0.014 15.4 0.0 4.3 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KUM64508.1 - 0.0045 17.4 0.4 19 5.7 0.1 4.5 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 KUM64508.1 - 0.008 16.7 0.1 14 6.3 0.0 3.5 3 0 0 3 3 3 2 HEAT-like repeat Condensin2nSMC PF12422.8 KUM64508.1 - 0.078 13.2 0.0 9.3 6.4 0.0 3.0 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit DUF3361 PF11841.8 KUM64508.1 - 0.78 9.7 2.4 1 9.3 0.0 2.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3361) SURF4 PF02077.15 KUM64510.1 - 2.2e-94 316.0 7.7 2.5e-94 315.8 7.7 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 KUM64510.1 - 0.2 12.3 19.4 0.26 11.9 5.2 3.0 3 2 0 3 3 3 0 DoxX LSM PF01423.22 KUM64512.1 - 1.1e-14 53.9 0.1 1.6e-14 53.3 0.1 1.3 1 0 0 1 1 1 1 LSM domain Bd3614-deam PF14439.6 KUM64513.1 - 0.049 13.7 1.8 0.066 13.3 1.8 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase SLX9 PF15341.6 KUM64514.1 - 0.00012 22.5 4.0 0.29 11.5 0.0 4.1 1 1 1 2 2 2 2 Ribosome biogenesis protein SLX9 TRAP_alpha PF03896.16 KUM64516.1 - 0.091 12.0 2.5 0.14 11.3 2.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RecC_C PF17946.1 KUM64516.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 RecC C-terminal domain ORC_WH_C PF18137.1 KUM64516.1 - 1.8 8.6 4.8 11 6.1 0.0 2.3 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Nop14 PF04147.12 KUM64516.1 - 4.4 5.4 10.4 6.3 4.9 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family TFB6 PF17110.5 KUM64516.1 - 5.3 6.7 6.0 40 3.9 0.1 2.4 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DNA_pol_phi PF04931.13 KUM64516.1 - 9.3 4.2 14.7 14 3.7 14.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi ADH_N PF08240.12 KUM64518.1 - 2.9e-26 91.5 0.7 4.9e-26 90.7 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM64518.1 - 3.2e-20 72.4 0.3 4.9e-20 71.8 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM64518.1 - 0.0026 18.8 0.1 0.0047 18.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KUM64518.1 - 0.0065 16.4 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase DUF4672 PF15716.5 KUM64518.1 - 0.24 11.0 0.0 0.45 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) PI3_PI4_kinase PF00454.27 KUM64519.1 - 1.8e-52 178.7 0.1 5.7e-52 177.0 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KUM64519.1 - 2.6e-09 36.7 0.2 6.2e-09 35.5 0.2 1.7 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 KUM64519.1 - 8e-08 31.9 2.0 1.7e-07 30.8 2.0 1.5 1 0 0 1 1 1 1 FAT domain APH PF01636.23 KUM64520.1 - 1e-10 42.0 0.1 8.9e-10 38.9 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family WBS_methylT PF12589.8 KUM64520.1 - 0.67 10.8 2.7 6.8 7.5 0.4 2.4 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome Nup192 PF11894.8 KUM64521.1 - 0 1439.0 7.4 0 1438.8 7.4 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DCB PF16213.5 KUM64521.1 - 0.06 13.0 1.0 0.98 9.1 1.0 2.8 1 1 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 TAN PF11640.8 KUM64522.1 - 1.3e-53 181.2 1.0 5.3e-53 179.2 0.7 2.0 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair Fungal_trans_2 PF11951.8 KUM64523.1 - 5.5e-06 25.4 0.7 0.00014 20.8 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.16 KUM64528.1 - 1.7e-47 162.1 30.6 1.7e-47 162.1 30.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM64528.1 - 1.6e-11 43.7 4.4 1.6e-11 43.7 4.4 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 KUM64528.1 - 2e-06 27.3 6.8 2e-06 27.3 6.8 2.2 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF2583 PF10762.9 KUM64528.1 - 0.13 12.7 0.5 0.61 10.6 0.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) MFS_1 PF07690.16 KUM64529.1 - 1.3e-19 70.4 57.5 6.9e-16 58.1 32.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM64529.1 - 0.044 12.2 14.0 0.0077 14.7 10.0 1.6 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) HhH-GPD PF00730.25 KUM64531.1 - 1.3e-05 25.6 0.0 4.1e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein G_glu_transpept PF01019.21 KUM64532.1 - 2.2e-166 554.6 0.0 2.5e-166 554.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase SET PF00856.28 KUM64533.1 - 3e-09 37.5 0.0 6.2e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 SET domain SAP PF02037.27 KUM64533.1 - 0.00076 19.2 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 SAP domain TPR_16 PF13432.6 KUM64533.1 - 0.0008 20.0 0.0 0.0018 18.9 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 KUM64533.1 - 0.0055 17.0 0.1 0.014 15.7 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KUM64533.1 - 0.012 15.4 0.2 0.98 9.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KUM64533.1 - 0.022 14.4 0.1 0.052 13.3 0.1 1.6 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.17 KUM64533.1 - 0.067 13.3 0.3 1.5 9.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RhoGAP PF00620.27 KUM64535.1 - 5.1e-28 97.8 0.0 8.5e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.12 KUM64536.1 - 1e-56 191.3 3.4 1.3e-56 190.9 3.4 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.9 KUM64537.1 - 1.6e-98 329.7 0.0 1.9e-98 329.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 T2SSE PF00437.20 KUM64537.1 - 0.078 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Aldo_ket_red PF00248.21 KUM64538.1 - 8.2e-67 225.5 0.0 9.4e-67 225.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Claudin_3 PF06653.11 KUM64538.1 - 0.062 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Prenyltrans PF00432.21 KUM64541.1 - 1.1e-54 181.9 6.8 2.1e-11 43.3 0.1 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KUM64541.1 - 5.8e-05 22.3 0.0 0.0085 15.2 0.0 2.8 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KUM64541.1 - 0.00013 21.2 0.0 0.033 13.3 0.0 3.3 3 1 1 4 4 4 2 Squalene-hopene cyclase N-terminal domain OPT PF03169.15 KUM64542.1 - 3.7e-145 485.0 45.8 2.4e-142 475.7 39.9 2.0 2 0 0 2 2 2 2 OPT oligopeptide transporter protein DUF4191 PF13829.6 KUM64542.1 - 1.5 8.1 3.1 3.3 7.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Hydrolase_4 PF12146.8 KUM64543.1 - 3.3e-16 59.3 0.0 8e-11 41.7 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KUM64543.1 - 5.1e-12 46.0 0.0 4.3e-08 33.1 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KUM64543.1 - 4.3e-06 26.3 0.0 2.2e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KUM64543.1 - 7.2e-06 26.8 0.0 0.00015 22.5 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 KUM64543.1 - 2.7e-05 23.9 0.0 0.00013 21.7 0.0 2.0 2 1 0 2 2 2 1 Serine hydrolase (FSH1) AXE1 PF05448.12 KUM64543.1 - 0.00016 20.5 0.1 0.32 9.6 0.0 2.5 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) DUF818 PF05677.12 KUM64543.1 - 0.0011 18.0 0.0 0.0016 17.5 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.11 KUM64543.1 - 0.0014 18.5 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 KUM64543.1 - 0.0092 15.6 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.20 KUM64543.1 - 0.012 15.3 0.0 0.049 13.3 0.0 1.8 2 0 0 2 2 2 0 Putative esterase PGAP1 PF07819.13 KUM64543.1 - 0.02 14.6 0.1 0.31 10.7 0.1 2.3 1 1 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 KUM64543.1 - 0.034 14.0 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 KUM64543.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 KUM64543.1 - 0.095 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S15 PF02129.18 KUM64543.1 - 0.17 11.5 0.0 1.1 8.8 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) ATP11 PF06644.11 KUM64544.1 - 3.5e-98 328.7 0.0 4.1e-98 328.5 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Cyclin PF08613.11 KUM64545.1 - 7.2e-39 133.7 2.5 3.3e-24 86.1 0.6 2.7 2 1 0 2 2 2 2 Cyclin Proteasome PF00227.26 KUM64546.1 - 1.7e-46 158.2 0.2 1.9e-46 157.9 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Evr1_Alr PF04777.13 KUM64547.1 - 3.6e-26 91.6 0.1 5e-26 91.1 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family FAD_SOX PF18371.1 KUM64547.1 - 0.035 14.5 0.0 0.052 13.9 0.0 1.3 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase APOBEC4 PF18775.1 KUM64547.1 - 0.082 13.1 0.3 0.2 11.9 0.2 1.6 1 1 1 2 2 2 0 APOBEC4 APOBEC1 PF18769.1 KUM64547.1 - 0.17 12.1 0.1 0.33 11.2 0.1 1.5 1 0 0 1 1 1 0 APOBEC1 Glyco_hydro_92 PF07971.12 KUM64548.1 - 2.5e-149 498.2 0.1 3e-149 497.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KUM64548.1 - 3.4e-65 220.2 0.2 5.9e-65 219.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain R3H PF01424.22 KUM64549.1 - 2.5e-11 43.4 0.0 5.9e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 R3H domain FancD2 PF14631.6 KUM64551.1 - 4.1 4.7 9.0 6.8 3.9 9.0 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Abhydrolase_1 PF00561.20 KUM64553.1 - 8.2e-14 51.9 0.0 5.1e-11 42.7 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM64553.1 - 4.6e-09 35.9 0.0 1.1e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KUM64553.1 - 4.4e-08 34.0 0.0 5.8e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KUM64553.1 - 4.6e-06 25.5 0.0 1e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Ndr family DUF1857 PF08982.11 KUM64554.1 - 5.4e-49 165.8 0.1 6e-49 165.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Mannosidase_ig PF17786.1 KUM64554.1 - 0.062 13.9 0.1 0.097 13.3 0.1 1.3 1 0 0 1 1 1 0 Mannosidase Ig/CBM-like domain Lipocalin PF00061.23 KUM64554.1 - 0.087 13.0 0.1 0.15 12.2 0.1 1.3 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family PhzC-PhzF PF02567.16 KUM64555.1 - 2.6e-46 158.4 0.0 3.1e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein adh_short PF00106.25 KUM64556.1 - 4.3e-34 117.7 0.0 9.5e-27 93.7 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM64556.1 - 1.3e-20 74.0 0.0 4.3e-16 59.2 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM64556.1 - 2.9e-11 43.6 0.0 4.5e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KUM64556.1 - 0.034 13.3 0.0 0.047 12.8 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MIOX PF05153.15 KUM64557.1 - 5.6e-116 386.4 7.5 3.6e-113 377.2 7.5 2.1 1 1 0 1 1 1 1 Myo-inositol oxygenase DUF1796 PF08795.10 KUM64557.1 - 0.014 15.3 0.2 0.022 14.7 0.2 1.3 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) HD PF01966.22 KUM64557.1 - 0.023 14.9 0.3 0.42 10.8 0.0 2.5 2 1 0 2 2 2 0 HD domain Retrotrans_gag PF03732.17 KUM64557.1 - 0.12 12.6 0.6 0.29 11.5 0.6 1.6 1 1 0 1 1 1 0 Retrotransposon gag protein IBR PF01485.21 KUM64558.1 - 1.4e-12 47.6 36.3 9.1e-07 29.0 6.7 3.3 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 KUM64558.1 - 0.0019 18.1 7.1 0.0019 18.1 7.1 3.9 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KUM64558.1 - 0.0025 17.6 2.3 0.0025 17.6 2.3 4.0 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM64558.1 - 0.013 15.4 6.7 0.013 15.4 6.7 4.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Actin PF00022.19 KUM64559.1 - 1.2e-105 353.5 0.0 6.8e-105 351.0 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KUM64559.1 - 0.097 11.5 0.0 0.24 10.2 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein TIMELESS PF04821.14 KUM64560.1 - 4.1e-89 298.5 0.1 4.1e-89 298.5 0.1 2.1 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 KUM64560.1 - 1.1e-62 213.0 30.3 5.2e-60 204.2 0.4 4.2 2 1 1 3 3 3 2 Timeless protein C terminal region 3HCDH_N PF02737.18 KUM64561.1 - 2.7e-51 174.0 1.8 3.5e-51 173.7 1.8 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KUM64561.1 - 7.9e-33 113.0 0.1 2.4e-32 111.4 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 KUM64561.1 - 0.00038 20.7 0.3 0.00092 19.5 0.3 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KUM64561.1 - 0.00095 19.4 0.8 0.002 18.3 0.3 1.8 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KUM64561.1 - 0.0069 16.0 0.3 0.017 14.8 0.1 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KUM64561.1 - 0.011 15.1 1.3 0.021 14.1 1.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KUM64561.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KUM64561.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 KUM64561.1 - 0.023 13.9 0.1 0.033 13.4 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KUM64561.1 - 0.045 13.1 0.5 0.26 10.6 0.1 2.1 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KUM64561.1 - 0.078 13.0 0.2 0.14 12.1 0.2 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TfuA PF07812.12 KUM64561.1 - 0.091 12.5 0.3 0.19 11.4 0.3 1.5 1 0 0 1 1 1 0 TfuA-like protein F420_oxidored PF03807.17 KUM64561.1 - 0.33 11.6 2.7 1.1 9.9 1.5 2.5 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_S64 PF08192.11 KUM64562.1 - 3.7e-05 22.5 0.0 0.00011 20.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase family S64 Peptidase_S32 PF05579.13 KUM64562.1 - 0.12 11.5 2.4 0.099 11.8 0.7 1.6 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 NmrA PF05368.13 KUM64564.1 - 2.2e-18 66.7 0.0 2.9e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM64564.1 - 7e-14 52.1 0.0 1.1e-13 51.4 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KUM64564.1 - 1.8e-06 27.6 0.1 1.3e-05 24.8 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KUM64564.1 - 0.00057 19.1 0.0 0.00081 18.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 KUM64564.1 - 0.0036 17.6 0.2 0.0059 16.9 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KUM64564.1 - 0.011 15.6 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 KUM64564.1 - 0.017 14.2 0.3 0.026 13.5 0.3 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KUM64564.1 - 0.046 13.2 0.1 0.073 12.5 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.20 KUM64564.1 - 0.049 13.7 0.1 0.09 12.8 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KUM64564.1 - 0.057 12.6 0.2 0.084 12.0 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KUM64564.1 - 0.064 12.6 0.1 0.29 10.5 0.1 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase LpxI_N PF17930.1 KUM64564.1 - 0.077 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 LpxI N-terminal domain CbiA PF01656.23 KUM64564.1 - 0.1 12.7 0.0 1.1 9.3 1.2 2.0 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain eIF-3c_N PF05470.12 KUM64566.1 - 2.4e-164 548.0 20.4 2.4e-164 548.0 20.4 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KUM64566.1 - 2.9e-12 47.0 2.4 2e-11 44.3 0.0 3.3 2 1 1 3 3 3 1 PCI domain DUF1385 PF07136.11 KUM64566.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) RRP7 PF12923.7 KUM64566.1 - 1.7 8.8 9.6 3.7 7.7 1.8 2.8 3 0 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain SDA1 PF05285.12 KUM64566.1 - 5.5 6.3 19.6 11 5.3 19.6 1.4 1 0 0 1 1 1 0 SDA1 Pkinase PF00069.25 KUM64567.1 - 1.3e-48 165.7 0.1 4.5e-48 163.9 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM64567.1 - 5e-21 75.1 0.0 9.8e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KUM64567.1 - 0.0018 18.2 0.1 0.0018 18.2 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KUM64567.1 - 0.012 15.2 0.4 0.069 12.7 0.0 2.0 1 1 1 2 2 2 0 RIO1 family Kdo PF06293.14 KUM64567.1 - 0.13 11.5 0.1 0.68 9.3 0.0 2.1 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans PF04082.18 KUM64569.1 - 1.2e-14 54.0 0.0 2.2e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM64569.1 - 4.6e-08 33.0 10.8 8.9e-08 32.1 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1192 PF06698.11 KUM64569.1 - 0.24 11.5 1.2 0.56 10.3 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) LysM PF01476.20 KUM64570.1 - 1.1e-07 31.7 0.1 1.7e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 LysM domain DUP PF00674.18 KUM64570.1 - 0.066 13.4 0.1 0.075 13.2 0.1 1.1 1 0 0 1 1 1 0 DUP family cNMP_binding PF00027.29 KUM64571.1 - 8.1e-32 109.2 0.7 6.2e-19 67.9 0.0 5.7 6 0 0 6 6 6 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KUM64571.1 - 2.1e-17 64.0 6.1 1.5e-15 57.9 6.1 2.9 1 1 0 1 1 1 1 Patatin-like phospholipase MARVEL PF01284.23 KUM64572.1 - 2.5e-15 56.8 9.2 3.3e-15 56.4 9.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF1774 PF08611.10 KUM64572.1 - 0.0083 16.4 4.9 0.041 14.2 0.0 2.4 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) DUF5504 PF17608.2 KUM64572.1 - 0.044 13.9 0.2 0.076 13.1 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5504) DUF2157 PF09925.9 KUM64572.1 - 0.38 10.5 5.9 0.42 10.4 1.4 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) EspB PF05802.11 KUM64573.1 - 0.071 13.1 0.7 0.15 12.1 0.7 1.4 1 0 0 1 1 1 0 Enterobacterial EspB protein CEP19 PF14933.6 KUM64573.1 - 0.22 11.8 5.1 0.83 9.9 1.8 2.3 2 0 0 2 2 2 0 CEP19-like protein Ribosomal_L13e PF01294.18 KUM64574.1 - 5.8e-76 254.3 7.9 7.8e-76 253.9 7.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Spc7 PF08317.11 KUM64575.1 - 0.12 11.2 0.5 0.18 10.6 0.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Oxidored-like PF09791.9 KUM64576.1 - 2.2e-23 81.6 3.0 4.5e-23 80.7 3.0 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 KUM64576.1 - 0.047 13.7 2.2 0.087 12.8 2.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5522) LRR19-TM PF15176.6 KUM64577.1 - 1.1 9.3 2.8 4.6 7.3 2.8 2.0 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain ABC2_membrane PF01061.24 KUM64578.1 - 1.1e-80 270.0 47.8 3.4e-45 154.1 17.9 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KUM64578.1 - 6.9e-39 133.5 0.0 1e-18 68.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KUM64578.1 - 3.9e-25 87.6 0.2 1.7e-21 75.9 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KUM64578.1 - 4e-15 55.8 23.1 2.6e-09 36.7 8.0 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 KUM64578.1 - 3.5e-10 40.4 0.0 1.2e-09 38.6 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KUM64578.1 - 7.8e-05 22.6 0.5 0.0057 16.6 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KUM64578.1 - 9.1e-05 22.4 0.1 0.12 12.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KUM64578.1 - 0.0002 21.8 0.3 0.059 13.7 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KUM64578.1 - 0.00042 20.0 0.2 0.082 12.7 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KUM64578.1 - 0.0023 18.2 0.3 0.81 10.0 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KUM64578.1 - 0.0026 17.9 0.1 1.8 8.7 0.1 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KUM64578.1 - 0.0028 17.3 0.9 1.4 8.5 0.3 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KUM64578.1 - 0.0037 16.9 0.0 0.039 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KUM64578.1 - 0.0039 17.7 0.0 4.1 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KUM64578.1 - 0.009 16.3 0.5 0.97 9.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KUM64578.1 - 0.013 15.5 0.1 3.9 7.6 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KUM64578.1 - 0.027 14.2 0.1 5.3 6.7 0.2 2.9 3 0 0 3 3 3 0 AAA domain MRVI1 PF05781.12 KUM64578.1 - 0.095 11.4 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 MRVI1 protein SMC_N PF02463.19 KUM64578.1 - 0.11 11.9 0.1 0.8 9.1 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.9 KUM64578.1 - 0.16 11.7 0.3 8.8 6.1 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KUM64578.1 - 0.18 11.7 0.5 5.8 6.8 0.2 2.3 2 0 0 2 2 2 0 NACHT domain DnaB_C PF03796.15 KUM64578.1 - 0.2 11.0 0.1 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain GCIP PF13324.6 KUM64579.1 - 1.6e-25 90.2 2.5 3.4e-25 89.1 2.5 1.5 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting bZIP_1 PF00170.21 KUM64579.1 - 0.0004 20.4 1.9 0.0011 19.0 1.9 1.7 1 0 0 1 1 1 1 bZIP transcription factor CdvA PF18822.1 KUM64579.1 - 0.13 12.1 1.4 0.34 10.8 0.5 2.1 2 0 0 2 2 2 0 CdvA-like coiled-coil domain LRR_4 PF12799.7 KUM64580.1 - 1.5e-32 111.1 48.7 2.2e-07 31.1 0.7 10.6 6 4 6 12 12 12 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KUM64580.1 - 1.6e-26 91.8 43.8 9.7e-09 34.9 3.1 8.1 6 2 2 8 8 8 7 Leucine rich repeat LRR_1 PF00560.33 KUM64580.1 - 2.2e-08 33.5 36.6 3.8 8.4 1.8 12.4 12 1 0 12 12 12 4 Leucine Rich Repeat LRR_9 PF14580.6 KUM64580.1 - 1.2e-06 28.2 18.2 0.062 12.8 0.3 5.1 3 3 2 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 KUM64580.1 - 0.0054 16.7 32.7 7.9 6.8 0.0 9.5 11 0 0 11 11 11 3 Leucine Rich repeat CSTF_C PF14304.6 KUM64580.1 - 0.045 13.3 0.2 0.2 11.3 0.2 2.2 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal CoA_transf_3 PF02515.17 KUM64581.1 - 3.7e-39 134.9 1.7 1.2e-38 133.3 1.0 1.9 1 1 1 2 2 2 1 CoA-transferase family III DUF3245 PF11595.8 KUM64583.1 - 5.5e-48 163.2 8.6 5.5e-48 163.2 8.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3245) Ribosomal_60s PF00428.19 KUM64583.1 - 0.02 15.4 11.9 0.02 15.4 11.9 3.4 2 1 2 4 4 4 0 60s Acidic ribosomal protein DUF4148 PF13663.6 KUM64583.1 - 2.3 8.4 9.3 3.2 8.0 5.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) p450 PF00067.22 KUM64584.1 - 1.7e-68 231.5 0.0 2.2e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HA2 PF04408.23 KUM64585.1 - 2e-10 40.9 0.0 4.3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Med27 PF11571.8 KUM64586.1 - 9.7e-20 70.7 0.0 2.1e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 DUF1387 PF07139.11 KUM64587.1 - 1.4 8.6 4.1 1.9 8.1 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) 2OG-FeII_Oxy_3 PF13640.6 KUM64589.1 - 4.2e-07 30.8 0.0 1.5e-05 25.8 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KUM64590.1 - 1.8e-23 83.0 84.6 7.2e-21 74.5 48.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 2OG-FeII_Oxy PF03171.20 KUM64591.1 - 2.5e-12 47.1 0.0 6.4e-12 45.9 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Suc_Fer-like PF06999.12 KUM64592.1 - 3.1e-69 232.8 0.0 3.6e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like USP19_linker PF16602.5 KUM64593.1 - 0.013 16.1 0.2 0.024 15.2 0.2 1.5 1 0 0 1 1 1 0 Linker region of USP19 deubiquitinase SNF2_N PF00176.23 KUM64595.1 - 9.2e-67 225.2 0.0 1.4e-66 224.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KUM64595.1 - 4e-18 65.8 0.0 1.7e-17 63.7 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM64595.1 - 1.1e-06 28.8 0.0 2.9e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KUM64595.1 - 4.7e-06 26.0 0.0 9e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Remorin_N PF03766.13 KUM64595.1 - 0.73 9.9 4.6 2.8 8.0 4.6 1.9 1 0 0 1 1 1 0 Remorin, N-terminal region GRIP PF01465.20 KUM64596.1 - 7.3e-17 61.0 0.2 1.6e-16 59.9 0.2 1.7 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.11 KUM64596.1 - 3.7e-09 35.9 138.8 0.0021 17.0 17.5 8.4 2 2 7 9 9 9 6 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KUM64596.1 - 1.7e-08 34.6 154.6 5.2e-05 23.3 12.8 10.9 3 2 7 10 10 10 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 KUM64596.1 - 3.9e-07 30.7 135.0 0.0016 18.9 6.9 8.5 1 1 4 6 6 5 3 Fez1 GAS PF13851.6 KUM64596.1 - 1.2e-06 28.0 137.7 0.023 14.0 13.0 9.7 2 2 7 9 9 9 5 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 KUM64596.1 - 3.5e-05 21.6 42.7 3.5e-05 21.6 42.7 5.7 1 1 2 3 3 3 2 Protein of unknown function (DUF3584) EzrA PF06160.12 KUM64596.1 - 5.8e-05 21.5 44.1 5.8e-05 21.5 44.1 5.2 2 2 3 5 5 5 2 Septation ring formation regulator, EzrA DHR10 PF18595.1 KUM64596.1 - 0.0003 20.8 9.2 0.0003 20.8 9.2 11.9 5 2 4 11 11 11 3 Designed helical repeat protein 10 domain HMMR_N PF15905.5 KUM64596.1 - 0.0008 19.0 132.9 0.06 12.8 19.3 7.2 2 2 2 5 5 5 3 Hyaluronan mediated motility receptor N-terminal DUF4201 PF13870.6 KUM64596.1 - 0.0019 18.0 4.8 0.0019 18.0 4.8 10.1 2 2 6 9 9 9 5 Domain of unknown function (DUF4201) Filament PF00038.21 KUM64596.1 - 0.0019 17.8 120.3 0.12 11.9 11.2 7.2 2 2 3 5 5 5 4 Intermediate filament protein FPP PF05911.11 KUM64596.1 - 0.002 16.5 129.3 0.0052 15.0 13.4 6.1 1 1 4 6 6 6 3 Filament-like plant protein, long coiled-coil CC2-LZ PF16516.5 KUM64596.1 - 0.0021 18.4 6.1 0.0021 18.4 6.1 12.3 3 2 5 10 10 10 2 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DivIC PF04977.15 KUM64596.1 - 0.0054 16.5 0.5 0.0054 16.5 0.5 15.2 7 5 9 16 16 16 3 Septum formation initiator Baculo_PEP_C PF04513.12 KUM64596.1 - 0.0058 16.7 47.1 0.64 10.1 1.8 7.3 3 2 4 8 8 8 2 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 KUM64596.1 - 0.0088 15.5 132.2 0.039 13.4 21.4 7.8 2 2 6 8 8 8 4 Golgin subfamily A member 5 Fib_alpha PF08702.10 KUM64596.1 - 0.057 13.6 84.6 0.77 9.9 3.6 9.0 2 2 4 8 8 8 0 Fibrinogen alpha/beta chain family Desmo_N PF06771.11 KUM64596.1 - 0.079 13.3 7.5 1.5 9.2 0.0 4.6 5 0 0 5 5 3 0 Viral Desmoplakin N-terminus DUF4763 PF15960.5 KUM64596.1 - 0.18 11.1 95.8 0.53 9.5 16.1 7.5 2 2 4 6 6 6 0 Domain of unknown function (DUF4763) Sigma70_ner PF04546.13 KUM64596.1 - 0.21 11.4 0.0 0.21 11.4 0.0 8.3 3 3 4 7 7 5 0 Sigma-70, non-essential region ATG16 PF08614.11 KUM64596.1 - 0.84 9.8 168.7 0.75 10.0 23.4 9.4 2 2 6 8 8 7 0 Autophagy protein 16 (ATG16) TolA_bind_tri PF16331.5 KUM64596.1 - 0.88 9.7 83.0 1.7 8.8 5.9 12.5 5 4 6 11 11 11 0 TolA binding protein trimerisation MAD PF05557.13 KUM64596.1 - 1.5 7.1 129.5 0.14 10.5 28.7 6.2 2 2 3 5 5 5 0 Mitotic checkpoint protein DUF1664 PF07889.12 KUM64596.1 - 2.9 7.9 86.9 0.62 10.1 5.7 11.0 2 2 8 12 12 12 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KUM64596.1 - 3 8.4 56.7 6.8 7.2 0.4 10.5 4 4 1 6 6 4 0 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 KUM64596.1 - 3.8 8.0 171.2 0.17 12.4 19.2 11.6 3 2 10 13 13 11 0 Apg6 coiled-coil region Pet191_N PF10203.9 KUM64597.1 - 0.0079 16.5 1.9 0.01 16.1 1.4 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Abhydro_lipase PF04083.16 KUM64598.1 - 2e-22 78.5 0.1 4.5e-22 77.4 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KUM64598.1 - 3.2e-22 79.4 0.0 7.6e-22 78.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM64598.1 - 6.3e-05 22.4 0.0 0.012 14.9 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KUM64598.1 - 0.0029 17.3 0.0 0.96 9.1 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Tannase PF07519.11 KUM64599.1 - 6.3e-148 493.6 4.2 7.3e-148 493.3 4.2 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase adh_short_C2 PF13561.6 KUM64600.1 - 1.4e-19 70.6 0.0 1.9e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM64600.1 - 1.6e-05 24.5 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short PF00106.25 KUM64601.1 - 3.3e-30 105.0 1.0 3.8e-30 104.8 1.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM64601.1 - 2e-28 99.5 1.2 2.6e-28 99.2 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM64601.1 - 4.1e-12 46.4 0.6 5e-12 46.1 0.6 1.0 1 0 0 1 1 1 1 KR domain SNF2_N PF00176.23 KUM64602.1 - 2.5e-75 253.4 0.6 7.2e-75 251.9 0.6 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 KUM64602.1 - 1.7e-24 85.7 0.3 6.8e-24 83.8 0.3 2.1 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.31 KUM64602.1 - 5.2e-21 75.1 1.7 2.1e-19 69.9 0.0 3.9 3 1 1 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 KUM64602.1 - 3.9e-19 68.7 14.5 3.9e-19 68.7 14.5 3.6 3 0 0 3 3 3 1 HSA SnAC PF14619.6 KUM64602.1 - 4.9e-15 55.9 1.7 4.9e-15 55.9 1.7 4.4 5 0 0 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 KUM64602.1 - 7.1e-14 51.3 1.7 2.3e-13 49.6 1.7 2.0 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 KUM64602.1 - 1.7e-10 41.2 0.0 1.7e-10 41.2 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PorB PF11565.8 KUM64602.1 - 0.12 12.8 0.8 23 5.5 0.3 2.9 2 0 0 2 2 2 0 Alpha helical Porin B BAR PF03114.18 KUM64603.1 - 4.7e-49 167.2 5.5 6.2e-49 166.8 5.5 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KUM64603.1 - 5.5e-06 25.7 2.9 7.3e-06 25.3 2.9 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking APG6_N PF17675.1 KUM64603.1 - 0.46 11.0 11.5 0.053 14.1 6.3 1.9 1 1 0 2 2 2 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KUM64603.1 - 1.1 9.3 11.7 3 7.9 11.7 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spo12 PF05032.12 KUM64604.1 - 2e-16 59.6 0.7 3.5e-16 58.8 0.7 1.4 1 0 0 1 1 1 1 Spo12 family Acyl-CoA_dh_1 PF00441.24 KUM64605.1 - 1.2e-29 103.4 1.4 2e-29 102.7 1.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KUM64605.1 - 1.8e-20 72.9 0.0 3.8e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KUM64605.1 - 1.3e-13 51.6 0.1 2.4e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KUM64605.1 - 9.6e-13 48.6 2.7 1.7e-12 47.7 2.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ribosomal_L5_C PF00673.21 KUM64606.1 - 7.2e-30 103.0 0.0 1.1e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KUM64606.1 - 0.00023 21.4 0.0 0.00043 20.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 UCH_1 PF13423.6 KUM64607.1 - 1.7e-16 60.8 0.0 1.3e-07 31.5 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KUM64607.1 - 3.1e-15 56.4 0.0 1e-14 54.7 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.25 KUM64609.1 - 7.8e-70 235.2 0.0 1.5e-69 234.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM64609.1 - 2.8e-48 164.5 0.0 1.3e-47 162.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KUM64609.1 - 6.7e-26 90.5 0.0 1.2e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 KUM64609.1 - 3.5e-16 59.4 0.0 8.6e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KUM64609.1 - 1.9e-13 50.3 0.1 9.8e-13 48.0 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 KUM64609.1 - 1.2e-06 28.0 0.0 0.0015 18.0 0.0 2.4 1 1 1 2 2 2 2 Kinase-like RA PF00788.23 KUM64609.1 - 9.3e-06 26.2 0.0 1.7e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pkinase_fungal PF17667.1 KUM64609.1 - 0.0019 17.0 0.0 0.004 16.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KUM64609.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KUM64610.1 - 6.6e-54 183.0 0.0 9.1e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM64610.1 - 2.5e-34 118.7 0.0 3.3e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM64610.1 - 1.3e-11 44.4 0.0 2.4e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Cas_APE2256 PF09651.10 KUM64610.1 - 0.042 13.8 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) Kdo PF06293.14 KUM64610.1 - 0.05 12.9 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sad1_UNC PF07738.13 KUM64611.1 - 3.4e-30 104.7 0.1 6.2e-30 103.9 0.1 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CEP63 PF17045.5 KUM64611.1 - 0.069 13.0 4.7 0.13 12.2 4.7 1.3 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Pep3_Vps18 PF05131.14 KUM64612.1 - 8.9e-45 152.2 0.0 5.9e-44 149.5 0.0 2.2 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KUM64612.1 - 5.1e-07 29.7 3.9 0.00032 20.6 0.0 3.6 3 1 2 5 5 5 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 KUM64612.1 - 0.00031 20.3 0.2 0.00062 19.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KUM64612.1 - 0.0008 19.3 0.2 0.0018 18.2 0.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KUM64612.1 - 0.00094 19.0 0.5 0.0025 17.6 0.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KUM64612.1 - 0.0031 17.2 4.8 0.0031 17.2 4.8 1.9 2 0 0 2 2 2 1 RING-like zinc finger DUF2175 PF09943.9 KUM64612.1 - 0.0045 17.2 0.1 0.016 15.5 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_2 PF13639.6 KUM64612.1 - 0.01 16.2 1.0 0.024 14.9 1.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KUM64612.1 - 0.032 14.2 0.4 0.079 13.0 0.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KUM64612.1 - 0.079 12.8 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KUM64612.1 - 0.12 12.7 0.4 0.49 10.7 0.6 1.9 2 0 0 2 2 1 0 RING-H2 zinc finger domain Vps39_2 PF10367.9 KUM64612.1 - 0.18 12.3 0.0 0.45 11.0 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3H2C3 PF17122.5 KUM64612.1 - 1.2 9.2 4.4 0.31 11.1 0.9 1.9 2 0 0 2 2 2 0 Zinc-finger Zn_clus PF00172.18 KUM64613.1 - 2.6e-10 40.2 10.2 5e-10 39.3 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM64613.1 - 3.6e-06 26.2 0.5 3.6e-06 26.2 0.5 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ada_Zn_binding PF02805.16 KUM64614.1 - 9.1e-29 99.3 4.6 1.4e-28 98.7 4.6 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KUM64614.1 - 7e-10 38.7 0.0 1.7e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KUM64614.1 - 1e-05 25.7 0.0 2.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain SNF2_N PF00176.23 KUM64617.1 - 7.8e-67 225.4 0.0 1.2e-66 224.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KUM64617.1 - 1.2e-17 63.6 0.0 2.4e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KUM64617.1 - 1.8e-15 57.2 0.0 4.3e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KUM64617.1 - 6.4e-11 41.9 10.1 1.3e-10 40.9 10.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KUM64617.1 - 4.7e-10 39.2 9.4 4.7e-10 39.2 9.4 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM64617.1 - 4.9e-09 35.9 10.7 4.9e-09 35.9 10.7 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KUM64617.1 - 1.5e-08 34.8 9.8 1.5e-08 34.8 9.8 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KUM64617.1 - 5.7e-07 29.4 9.1 1.2e-06 28.3 9.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KUM64617.1 - 6.4e-07 29.4 9.5 1.2e-06 28.5 9.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KUM64617.1 - 7.5e-07 29.1 6.2 1.7e-06 27.9 6.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KUM64617.1 - 1.3e-05 24.9 8.3 1.3e-05 24.9 8.3 1.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KUM64617.1 - 2.9e-05 24.3 6.2 7.5e-05 22.9 6.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KUM64617.1 - 0.0014 18.4 5.8 0.0036 17.1 5.8 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 KUM64617.1 - 0.11 12.7 0.2 0.56 10.4 0.0 2.3 3 0 0 3 3 2 0 U-box domain zf-RING_4 PF14570.6 KUM64617.1 - 0.12 12.2 7.6 0.3 10.9 7.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KUM64617.1 - 0.64 10.2 10.4 0.078 13.1 5.9 1.8 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KUM64617.1 - 0.68 9.7 4.1 2.2 8.1 4.1 1.9 1 0 0 1 1 1 0 RING-like zinc finger DUF1272 PF06906.11 KUM64617.1 - 1.1 9.5 5.5 2.1 8.5 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Peptidase_S49_N PF08496.10 KUM64617.1 - 7 6.7 7.3 16 5.6 7.3 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ribonuc_L-PSP PF01042.21 KUM64618.1 - 3.4e-23 81.9 0.0 4.2e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF5130 PF17174.4 KUM64618.1 - 0.044 14.0 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5130) HpcH_HpaI PF03328.14 KUM64619.1 - 4.2e-32 111.1 0.2 5.3e-32 110.7 0.2 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 KUM64619.1 - 0.001 18.2 0.1 0.028 13.5 0.1 2.5 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain MFS_1 PF07690.16 KUM64620.1 - 2.4e-39 135.3 18.9 2.4e-39 135.3 18.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KUM64621.1 - 4.6e-19 68.5 0.6 6.3e-19 68.0 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PaaB PF06243.11 KUM64621.1 - 0.093 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Phenylacetic acid degradation B NDUFA12 PF05071.16 KUM64622.1 - 1.2e-30 106.2 0.3 1.6e-30 105.8 0.3 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Abhydrolase_6 PF12697.7 KUM64625.1 - 2.4e-17 64.3 1.6 2.9e-17 64.0 1.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KUM64625.1 - 0.0092 15.6 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase PGAP1 PF07819.13 KUM64625.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 KUM64625.1 - 0.019 14.5 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 KUM64625.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DDOST_48kD PF03345.14 KUM64626.1 - 3.8e-155 516.8 0.0 4.4e-155 516.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta NAPRTase_C PF17956.1 KUM64626.1 - 0.025 15.0 0.0 0.077 13.4 0.0 1.9 1 1 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain DUF1116 PF06545.11 KUM64626.1 - 0.05 13.1 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) 2OG-FeII_Oxy PF03171.20 KUM64627.1 - 1e-12 48.4 0.0 2.2e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KUM64627.1 - 1.6e-10 41.8 0.0 3.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal adh_short_C2 PF13561.6 KUM64628.1 - 7.4e-47 159.9 0.5 8.5e-47 159.7 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM64628.1 - 2.5e-45 154.3 0.8 3.3e-45 154.0 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM64628.1 - 1.4e-09 38.1 0.5 2.1e-09 37.5 0.5 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KUM64628.1 - 8.6e-06 25.4 0.3 1.4e-05 24.7 0.3 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KUM64628.1 - 1.6e-05 24.5 0.2 4.8e-05 22.9 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KUM64628.1 - 5.6e-05 23.1 0.6 0.00019 21.4 0.3 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KUM64628.1 - 5.8e-05 22.4 0.1 7.9e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KUM64628.1 - 0.00039 20.7 0.1 0.00058 20.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Gtr1_RagA PF04670.12 KUM64628.1 - 0.087 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ACT_7 PF13840.6 KUM64628.1 - 0.091 12.6 0.1 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 ACT domain TIP49_C PF17856.1 KUM64628.1 - 0.095 12.8 0.1 0.77 9.9 0.0 2.4 2 1 1 3 3 3 0 TIP49 AAA-lid domain LTV PF04180.14 KUM64629.1 - 1.9e-117 393.3 5.2 2.2e-117 393.1 5.2 1.0 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.23 KUM64630.1 - 1.2e-16 60.8 0.2 3.6e-14 52.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KUM64630.1 - 4.1e-07 29.7 0.1 1.3e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KUM64630.1 - 2.3e-05 24.4 0.1 0.011 15.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KUM64630.1 - 0.0048 17.0 4.5 0.25 11.4 0.2 3.3 3 1 1 4 4 4 2 Dynamin family AIG1 PF04548.16 KUM64630.1 - 0.0087 15.4 1.2 0.01 15.1 0.0 1.7 2 0 0 2 2 2 1 AIG1 family Glyco_transf_25 PF01755.17 KUM64630.1 - 0.071 13.0 0.8 0.21 11.4 0.8 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) PLDc_2 PF13091.6 KUM64631.1 - 3.7e-15 56.0 0.0 3.5e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KUM64631.1 - 5.6e-09 35.8 0.5 0.005 17.0 0.4 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif HAD_2 PF13419.6 KUM64632.1 - 7.6e-20 71.7 0.0 1e-19 71.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KUM64632.1 - 8e-10 39.4 0.0 1.1e-09 38.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KUM64632.1 - 3.9e-07 30.6 0.4 6.3e-07 30.0 0.4 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KUM64632.1 - 0.00057 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Glyco_hydro_3_C PF01915.22 KUM64632.1 - 0.04 13.9 0.1 0.08 12.9 0.1 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain TPR_14 PF13428.6 KUM64633.1 - 4.2e-08 33.4 28.3 1.1 10.3 0.6 8.5 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 KUM64633.1 - 2.3e-05 24.6 10.4 2.6 8.4 0.1 5.6 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KUM64633.1 - 5.4e-05 22.8 7.2 2.3 8.2 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KUM64633.1 - 0.00013 21.8 16.2 1.9 8.8 0.2 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KUM64633.1 - 0.00013 22.4 8.0 0.33 11.5 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KUM64633.1 - 0.0035 17.4 11.1 8.5 6.9 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 KUM64633.1 - 0.0046 17.6 18.3 0.43 11.3 0.1 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat PUL PF08324.11 KUM64633.1 - 0.035 13.3 0.1 1.6 7.9 0.0 2.9 3 0 0 3 3 3 0 PUL domain ANAPC3 PF12895.7 KUM64633.1 - 0.11 12.7 0.0 0.48 10.7 0.0 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 MBOAT_2 PF13813.6 KUM64634.1 - 4.5e-21 74.9 3.4 4.5e-21 74.9 3.4 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family RIX1 PF08167.12 KUM64635.1 - 1.7e-60 204.0 2.9 1.7e-60 204.0 2.9 2.8 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis zf-C2H2_6 PF13912.6 KUM64636.1 - 0.056 13.5 0.3 0.15 12.1 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KUM64636.1 - 0.14 12.7 0.8 0.14 12.7 0.8 4.0 3 1 1 4 4 4 0 Zinc finger, C2H2 type DUF629 PF04780.12 KUM64636.1 - 2 6.9 3.7 19 3.6 3.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 KUM64636.1 - 2 9.5 9.8 1 10.4 0.5 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger EST1_DNA_bind PF10373.9 KUM64637.1 - 2.9e-71 240.2 0.4 5.7e-70 236.0 0.0 2.1 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KUM64637.1 - 5.3e-25 88.6 0.7 2.6e-22 79.9 0.3 2.5 2 0 0 2 2 2 2 Telomerase activating protein Est1 PfkB PF00294.24 KUM64638.1 - 3.7e-67 226.8 0.1 4.2e-67 226.6 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KUM64638.1 - 0.034 13.5 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DUF1770 PF08589.10 KUM64639.1 - 1e-31 109.8 0.9 1.4e-31 109.4 0.9 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.6 KUM64640.1 - 6.2e-08 32.0 0.0 1.3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Ribosomal_L2_C PF03947.18 KUM64641.1 - 9.3e-43 145.4 5.6 1.6e-42 144.7 5.6 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KUM64641.1 - 1.2e-12 47.6 0.1 3.5e-12 46.1 0.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Amidohydro_3 PF07969.11 KUM64642.1 - 4.4e-67 227.6 0.1 5e-67 227.4 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KUM64642.1 - 4.3e-16 59.2 0.1 1.2e-12 47.9 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Fungal_trans_2 PF11951.8 KUM64643.1 - 1.7e-15 56.7 0.4 2e-15 56.5 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KUM64645.1 - 2.3e-16 59.6 2.8 2.8e-16 59.3 0.3 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KUM64645.1 - 5.6e-12 45.4 8.2 2.5e-05 24.5 2.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM64645.1 - 7e-09 35.8 8.3 0.00086 19.9 2.3 3.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KUM64645.1 - 2.3e-08 34.1 9.9 5.6e-08 32.9 2.4 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KUM64645.1 - 2e-05 24.7 1.1 0.23 11.8 0.5 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KUM64645.1 - 0.00044 20.1 2.2 0.35 10.8 0.2 2.9 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KUM64645.1 - 0.0055 16.7 7.6 0.94 9.6 2.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 KUM64645.1 - 0.014 15.8 3.2 0.014 15.8 3.2 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger BolA PF01722.18 KUM64645.1 - 0.089 13.1 1.2 1.5 9.1 1.0 2.8 1 1 0 1 1 1 0 BolA-like protein zf-met PF12874.7 KUM64645.1 - 0.12 12.8 3.2 8.7 6.9 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type gag_pre-integrs PF13976.6 KUM64645.1 - 0.71 9.8 4.5 2.1 8.2 0.5 2.8 1 1 1 2 2 2 0 GAG-pre-integrase domain zf-C2H2_3rep PF18868.1 KUM64645.1 - 1.6 9.4 4.5 20 5.9 3.3 2.3 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 KUM64645.1 - 3.9 7.3 7.2 0.61 9.9 2.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Abhydrolase_3 PF07859.13 KUM64646.1 - 2.9e-39 135.1 0.0 1.5e-37 129.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KUM64646.1 - 6.3e-07 28.6 0.0 4.3e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase HATPase_c PF02518.26 KUM64647.1 - 1.5e-30 106.0 0.0 4.3e-30 104.5 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KUM64647.1 - 6.8e-19 68.1 0.0 2.4e-18 66.3 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KUM64647.1 - 1.3e-18 66.8 0.0 4.8e-18 65.0 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KUM64647.1 - 2.5e-13 50.5 0.0 6.5e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.6 KUM64647.1 - 4.2e-10 40.3 0.0 1.9e-09 38.1 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain GAF PF01590.26 KUM64647.1 - 8.3e-09 36.2 0.0 2e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KUM64647.1 - 1.1e-05 25.7 0.0 2.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KUM64647.1 - 9.2e-05 21.9 0.0 0.0004 19.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain HATPase_c_3 PF13589.6 KUM64647.1 - 0.00077 19.3 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NB-ARC PF00931.22 KUM64647.1 - 0.00081 18.6 1.3 0.89 8.7 0.4 3.0 3 0 0 3 3 3 2 NB-ARC domain NACHT PF05729.12 KUM64647.1 - 0.011 15.7 0.5 0.75 9.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_35 PF14516.6 KUM64647.1 - 0.022 13.6 0.0 0.24 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain DUF2514 PF10721.9 KUM64647.1 - 0.034 14.2 0.3 0.034 14.2 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) DUF4106 PF13388.6 KUM64649.1 - 6.2 5.9 20.7 0.058 12.6 4.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) CENP-H PF05837.12 KUM64650.1 - 1.8e-29 102.4 14.6 2.2e-29 102.1 7.0 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) KIAA1430 PF13879.6 KUM64650.1 - 0.04 14.7 0.7 0.082 13.7 0.7 1.6 1 0 0 1 1 1 0 KIAA1430 homologue ATG11 PF10377.9 KUM64651.1 - 5.3e-45 152.6 0.0 5.3e-45 152.6 0.0 4.1 3 1 0 3 3 3 1 Autophagy-related protein 11 APG17 PF04108.12 KUM64651.1 - 5e-08 32.5 1.5 2.4e-05 23.6 1.1 5.6 3 2 1 4 4 4 2 Autophagy protein Apg17 CENP-F_leu_zip PF10473.9 KUM64651.1 - 0.0078 16.2 7.2 0.0078 16.2 7.2 7.5 6 3 1 7 7 7 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SLATT_5 PF18160.1 KUM64651.1 - 0.18 11.1 0.6 0.83 9.0 0.6 2.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 ATG16 PF08614.11 KUM64651.1 - 0.41 10.9 85.6 0.094 12.9 6.9 6.9 5 2 1 6 6 6 0 Autophagy protein 16 (ATG16) Ssu72 PF04722.13 KUM64651.1 - 0.41 10.2 2.1 1.1 8.8 2.1 1.7 1 0 0 1 1 1 0 Ssu72-like protein ACP_PD PF04336.12 KUM64651.1 - 1.2 9.6 8.7 1.2 9.6 2.2 3.8 3 0 0 3 3 3 0 Acyl carrier protein phosphodiesterase DUF948 PF06103.11 KUM64651.1 - 2.7 8.3 18.6 7.1 7.0 0.1 6.8 7 0 0 7 7 7 0 Bacterial protein of unknown function (DUF948) YebO PF13974.6 KUM64651.1 - 3.9 7.6 6.5 1.1 9.4 0.8 3.2 2 0 0 2 2 2 0 YebO-like protein Vps52 PF04129.12 KUM64651.1 - 6.1 5.5 16.7 0.027 13.2 5.5 2.4 1 1 0 2 2 2 0 Vps52 / Sac2 family HMG_box PF00505.19 KUM64652.1 - 3.8e-25 88.1 0.4 3.8e-25 88.1 0.4 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KUM64652.1 - 2.3e-17 63.3 1.0 2.3e-17 63.3 1.0 1.9 2 1 1 3 3 3 1 HMG-box domain Ccdc124 PF06244.12 KUM64652.1 - 0.014 15.9 0.0 0.014 15.9 0.0 2.3 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 YABBY PF04690.13 KUM64652.1 - 0.41 11.2 2.6 0.27 11.8 0.9 1.6 1 1 1 2 2 2 0 YABBY protein Allantoicase PF03561.15 KUM64654.1 - 2.8e-85 283.6 0.0 8.5e-42 142.5 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Pkinase PF00069.25 KUM64656.1 - 6.6e-68 228.9 0.0 1e-67 228.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM64656.1 - 1.1e-39 136.3 0.0 2.1e-39 135.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KUM64656.1 - 6.3e-17 61.1 0.4 1.1e-16 60.3 0.4 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KUM64656.1 - 8.8e-06 24.9 0.0 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KUM64656.1 - 2.9e-05 23.5 0.1 5.9e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KUM64656.1 - 4.4e-05 22.9 0.0 0.00065 19.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KUM64656.1 - 0.00027 20.9 0.0 0.0016 18.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 KUM64656.1 - 0.078 12.6 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 KUM64656.1 - 0.12 12.0 0.2 0.33 10.5 0.2 1.8 1 1 0 1 1 1 0 RIO1 family OPT PF03169.15 KUM64657.1 - 6.7e-64 216.6 18.8 7.9e-64 216.4 18.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Proteasom_Rpn13 PF04683.13 KUM64658.1 - 2.3e-28 98.5 0.0 3.6e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KUM64658.1 - 4.3e-12 46.2 4.4 5.2e-11 42.7 4.2 2.4 2 1 0 2 2 2 1 UCH-binding domain Ion_trans PF00520.31 KUM64659.1 - 6e-124 412.1 81.6 8.9e-43 146.3 5.8 4.9 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 KUM64659.1 - 0.00018 21.2 0.0 0.00044 20.0 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 KUM64659.1 - 0.0076 15.7 0.0 0.045 13.3 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KUM64659.1 - 0.1 12.6 0.0 0.67 10.0 0.0 2.5 1 0 0 1 1 1 0 EF-hand domain ORC6 PF05460.13 KUM64660.1 - 4 6.6 10.0 4.5 6.4 10.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SET PF00856.28 KUM64661.1 - 5.9e-18 65.8 0.1 1.3e-17 64.7 0.1 1.6 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.16 KUM64661.1 - 3.9e-11 43.6 5.2 3.9e-11 43.6 5.2 2.4 2 0 0 2 2 2 1 Pre-SET motif Sas10 PF09368.10 KUM64662.1 - 1.4e-27 95.9 10.9 1.4e-27 95.9 10.9 2.5 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KUM64662.1 - 5.1e-14 52.7 0.0 5.1e-14 52.7 0.0 3.0 2 1 1 3 3 3 1 Sas10/Utp3/C1D family adh_short PF00106.25 KUM64663.1 - 4e-25 88.4 0.0 5.5e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM64663.1 - 1.9e-14 53.8 0.0 3.1e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM64663.1 - 6.7e-08 32.7 0.1 1.2e-07 31.8 0.1 1.5 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KUM64663.1 - 8e-05 22.2 0.1 0.00034 20.1 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KUM64663.1 - 0.00089 18.8 0.2 0.0026 17.3 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KUM64663.1 - 0.0025 17.2 0.2 0.0045 16.3 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 KUM64663.1 - 0.0047 16.8 0.8 0.019 14.9 0.8 2.0 2 1 0 2 2 2 1 NAD(P)H-binding Pyr_redox_3 PF13738.6 KUM64663.1 - 0.006 15.9 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KUM64663.1 - 0.029 14.4 0.1 0.054 13.6 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KUM64663.1 - 0.039 14.1 0.1 0.066 13.4 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.15 KUM64663.1 - 0.07 13.0 0.4 0.12 12.2 0.4 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_7 PF13241.6 KUM64663.1 - 0.094 13.2 0.2 0.18 12.3 0.2 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 KUM64663.1 - 0.097 13.3 0.1 0.21 12.2 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FA_hydroxylase PF04116.13 KUM64664.1 - 9.5e-17 61.6 6.1 9.5e-17 61.6 6.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L6e PF01159.19 KUM64665.1 - 3.1e-39 134.0 0.3 5.3e-39 133.2 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e AGP PF06376.12 KUM64665.1 - 0.0066 16.3 0.2 0.068 13.0 0.4 2.4 2 0 0 2 2 2 1 Arabinogalactan peptide EF1_GNE PF00736.19 KUM64666.1 - 5.3e-33 113.0 2.0 5.3e-33 113.0 2.0 1.9 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KUM64666.1 - 2.7e-11 43.7 3.4 2.7e-11 43.7 3.4 2.9 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 KUM64666.1 - 0.00025 21.2 0.2 0.00055 20.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KUM64666.1 - 0.00036 20.7 0.6 0.0014 18.8 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KUM64666.1 - 0.13 12.3 0.2 2.1 8.4 0.2 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA_2 PF07724.14 KUM64667.1 - 4.7e-46 157.0 0.0 8.2e-44 149.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KUM64667.1 - 1.3e-35 121.4 1.6 1.3e-35 121.4 1.6 2.6 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KUM64667.1 - 3.5e-27 94.3 0.2 1e-26 92.8 0.2 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KUM64667.1 - 1.4e-18 67.6 0.0 6.4e-10 39.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KUM64667.1 - 3.7e-12 46.4 0.9 7.5e-08 32.5 0.0 3.4 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KUM64667.1 - 1e-08 35.8 10.7 0.00017 22.0 0.4 4.5 3 2 1 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KUM64667.1 - 1.8e-07 31.1 0.8 0.00028 20.6 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 KUM64667.1 - 3.4e-07 30.6 4.6 0.021 15.1 0.0 4.2 3 3 0 3 3 3 2 AAA domain TniB PF05621.11 KUM64667.1 - 3e-06 26.8 0.0 0.019 14.4 0.0 3.8 3 1 0 3 3 2 1 Bacterial TniB protein AAA_14 PF13173.6 KUM64667.1 - 1e-05 25.6 0.0 0.1 12.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KUM64667.1 - 1.1e-05 25.5 0.1 0.14 12.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_7 PF12775.7 KUM64667.1 - 1.9e-05 24.3 0.0 0.029 13.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 KUM64667.1 - 2.5e-05 24.3 3.8 1.1 9.1 0.1 4.7 3 3 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KUM64667.1 - 5.3e-05 23.5 1.5 0.015 15.5 0.0 3.5 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KUM64667.1 - 0.00015 21.5 0.0 0.69 9.6 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 KUM64667.1 - 0.00026 20.8 0.1 0.16 11.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.22 KUM64667.1 - 0.00035 20.3 0.1 0.068 12.8 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KUM64667.1 - 0.00069 20.2 1.3 0.85 10.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.6 KUM64667.1 - 0.0013 19.1 0.3 0.13 12.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KUM64667.1 - 0.0016 18.8 0.0 0.91 9.9 0.0 2.8 2 1 0 2 2 2 1 RNA helicase ResIII PF04851.15 KUM64667.1 - 0.0021 18.1 0.2 4.6 7.2 0.0 3.2 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KUM64667.1 - 0.0032 17.2 1.6 0.13 11.9 0.1 3.4 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 KUM64667.1 - 0.0043 17.0 0.1 2.9 7.9 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KUM64667.1 - 0.0061 17.1 1.1 2.5 8.6 0.0 3.3 3 0 0 3 3 3 1 ABC transporter PduV-EutP PF10662.9 KUM64667.1 - 0.0079 15.9 0.0 0.26 11.0 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation TrwB_AAD_bind PF10412.9 KUM64667.1 - 0.0097 14.9 0.1 0.42 9.5 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain RsgA_GTPase PF03193.16 KUM64667.1 - 0.01 15.7 0.0 3.7 7.4 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase Mg_chelatase PF01078.21 KUM64667.1 - 0.011 15.2 0.2 2.8 7.3 0.1 3.1 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 KUM64667.1 - 0.011 15.9 0.1 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KUM64667.1 - 0.022 14.3 0.6 0.49 9.9 0.2 2.9 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 KUM64667.1 - 0.023 13.9 0.3 0.71 9.0 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_21 PF13304.6 KUM64667.1 - 0.03 14.2 3.0 0.89 9.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF853 PF05872.12 KUM64667.1 - 0.033 12.8 0.1 0.033 12.8 0.1 2.3 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF853) ATP_bind_1 PF03029.17 KUM64667.1 - 0.034 13.9 0.1 0.54 10.0 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 KUM64667.1 - 0.039 14.1 2.0 7.3 6.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_6 PF12774.7 KUM64667.1 - 0.039 12.9 0.0 4.2 6.3 0.0 2.9 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region NTPase_1 PF03266.15 KUM64667.1 - 0.046 13.6 0.1 0.56 10.1 0.0 2.6 2 0 0 2 2 2 0 NTPase UvrD-helicase PF00580.21 KUM64667.1 - 0.071 12.6 2.9 0.42 10.1 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Zeta_toxin PF06414.12 KUM64667.1 - 0.077 12.3 1.8 3 7.1 0.0 2.7 3 0 0 3 3 2 0 Zeta toxin GAS PF13851.6 KUM64667.1 - 0.58 9.5 13.1 1.6 8.0 13.1 1.7 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PKcGMP_CC PF16808.5 KUM64667.1 - 1.1 9.2 7.3 0.87 9.5 0.6 2.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4349 PF14257.6 KUM64667.1 - 1.4 8.3 11.0 0.69 9.3 2.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF4407 PF14362.6 KUM64667.1 - 4.2 6.6 11.3 7.5 5.8 11.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OEP PF02321.18 KUM64667.1 - 5.2 6.8 12.7 11 5.8 12.7 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein GrpE PF01025.19 KUM64667.1 - 10 5.8 10.3 27 4.4 10.3 1.8 1 0 0 1 1 1 0 GrpE MutS_V PF00488.21 KUM64668.1 - 9.3e-19 68.2 0.0 1.5e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KUM64668.1 - 3.7e-14 53.4 0.0 5.4e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KUM64668.1 - 0.0099 16.2 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.6 KUM64668.1 - 0.012 15.4 0.2 0.4 10.4 0.1 3.0 2 1 1 3 3 3 0 P-loop containing region of AAA domain T2SSE PF00437.20 KUM64668.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4290 PF14123.6 KUM64668.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) MutS_V PF00488.21 KUM64669.1 - 8.6e-23 81.3 0.0 1e-22 81.1 0.0 1.1 1 0 0 1 1 1 1 MutS domain V AAT PF03417.16 KUM64671.1 - 3.5e-16 59.6 0.0 4e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase AMP-binding PF00501.28 KUM64672.1 - 1.1e-73 248.2 0.0 5.8e-73 245.9 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 KUM64672.1 - 1.9e-58 198.3 0.0 3e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 KUM64672.1 - 3.4e-53 180.2 0.4 3.5e-52 176.9 0.0 2.6 3 0 0 3 3 3 1 KR domain PS-DH PF14765.6 KUM64672.1 - 1.3e-50 172.4 0.1 2.3e-50 171.5 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KUM64672.1 - 5.8e-43 147.6 0.0 1e-42 146.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KUM64672.1 - 8.2e-35 120.2 0.0 3.5e-34 118.1 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 KUM64672.1 - 4.3e-28 97.7 0.0 9.3e-28 96.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KUM64672.1 - 8.5e-19 68.1 0.0 2.4e-18 66.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KUM64672.1 - 3.7e-17 62.4 1.7 4.1e-10 39.9 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KUM64672.1 - 1.7e-14 54.2 0.0 5e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 KUM64672.1 - 2.4e-14 53.4 0.0 5.3e-12 45.7 0.0 2.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KUM64672.1 - 9.7e-14 51.3 0.7 3.9e-13 49.3 0.2 2.3 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KUM64672.1 - 1.2e-13 51.6 0.0 6.1e-13 49.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM64672.1 - 3.7e-13 49.6 0.0 8.5e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM64672.1 - 5.1e-11 43.1 0.0 1.4e-10 41.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 KUM64672.1 - 2.8e-10 39.7 0.0 6.2e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.6 KUM64672.1 - 7.7e-10 38.8 0.0 1.9e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM64672.1 - 1.1e-08 34.7 0.0 3.5e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family ketoacyl-synt PF00109.26 KUM64672.1 - 2.2e-06 27.5 0.0 5.3e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.6 KUM64672.1 - 7.2e-06 25.7 0.1 1.4e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_16 PF10294.9 KUM64672.1 - 0.00081 19.2 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 Lysine methyltransferase Semialdhyde_dh PF01118.24 KUM64672.1 - 0.0068 16.8 0.0 0.026 14.9 0.0 2.0 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RrnaAD PF00398.20 KUM64672.1 - 0.015 14.4 0.1 0.066 12.3 0.0 1.9 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.12 KUM64672.1 - 0.017 14.6 0.0 0.047 13.2 0.0 1.6 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase Glyco_hyd_65N_2 PF14498.6 KUM64673.1 - 1.6e-63 214.7 0.0 2.2e-63 214.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Sugar_tr PF00083.24 KUM64674.1 - 1.6e-59 201.9 27.1 2e-59 201.7 27.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM64674.1 - 9.7e-25 87.2 29.2 1.2e-24 86.9 29.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_1 PF00232.18 KUM64676.1 - 4.6e-146 486.8 1.5 5.5e-146 486.5 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 RSN1_7TM PF02714.15 KUM64677.1 - 1.1e-78 264.3 22.6 1.1e-78 264.3 22.6 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KUM64677.1 - 2.7e-43 147.4 1.4 2.7e-43 147.4 1.4 2.8 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KUM64677.1 - 6.7e-41 140.4 0.0 9.6e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Bac_luciferase PF00296.20 KUM64677.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Luciferase-like monooxygenase Grg1 PF11034.8 KUM64678.1 - 2e-28 98.4 13.9 2.5e-28 98.1 13.9 1.1 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 DUF885 PF05960.11 KUM64679.1 - 4.1e-44 152.1 1.0 2.7e-43 149.4 1.0 2.0 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF885) OPT PF03169.15 KUM64680.1 - 3.2e-99 333.3 22.9 3.7e-99 333.1 22.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4078 PF13300.6 KUM64681.1 - 3.2e-26 91.5 10.7 3.2e-26 91.5 10.7 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4078) Homoserine_dh PF00742.19 KUM64682.1 - 4.9e-52 176.3 0.0 6.4e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KUM64682.1 - 1.4e-15 57.9 0.0 2.7e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KUM64682.1 - 0.083 13.2 0.0 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF3445 PF11927.8 KUM64683.1 - 1.4e-79 266.9 0.0 1.7e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) FSH1 PF03959.13 KUM64684.1 - 3.1e-56 190.4 0.0 3.6e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KUM64684.1 - 2.8e-05 24.0 0.3 0.0064 16.3 0.0 2.7 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KUM64684.1 - 0.0083 15.6 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KUM64684.1 - 0.014 14.9 0.0 0.031 13.7 0.0 1.8 1 1 0 1 1 1 0 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KUM64684.1 - 0.024 13.9 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 HycA_repressor PF11046.8 KUM64685.1 - 0.071 13.3 0.0 0.087 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons ASFV_J13L PF05568.11 KUM64686.1 - 0.027 14.2 4.4 0.054 13.3 0.2 2.3 1 1 1 2 2 2 0 African swine fever virus J13L protein SET PF00856.28 KUM64687.1 - 8.4e-10 39.3 0.0 1.5e-09 38.5 0.0 1.7 1 1 0 1 1 1 1 SET domain UIM PF02809.20 KUM64688.1 - 0.15 12.1 0.8 0.57 10.2 0.8 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF1776 PF08643.10 KUM64688.1 - 0.17 11.3 0.0 0.36 10.1 0.0 1.5 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Response_reg PF00072.24 KUM64690.1 - 6.7e-20 71.3 0.0 1.4e-13 51.0 0.0 2.2 2 0 0 2 2 2 2 Response regulator receiver domain Fungal_trans_2 PF11951.8 KUM64691.1 - 5.1e-07 28.8 4.2 1.3e-06 27.5 0.0 2.6 3 0 0 3 3 3 2 Fungal specific transcription factor domain Cu-oxidase_2 PF07731.14 KUM64692.1 - 3.2e-38 130.6 15.2 1.6e-37 128.3 1.2 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KUM64692.1 - 4.3e-38 130.0 2.0 4.3e-38 130.0 2.0 2.4 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KUM64692.1 - 5.2e-28 98.2 2.0 1e-21 77.7 0.2 3.4 3 1 1 4 4 4 2 Multicopper oxidase SH3_1 PF00018.28 KUM64693.1 - 8.7e-09 34.9 0.1 1.4e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KUM64693.1 - 2e-06 27.4 0.0 3.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KUM64693.1 - 8.4e-06 25.6 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain ADH_zinc_N PF00107.26 KUM64694.1 - 7e-25 87.5 0.5 1.2e-24 86.8 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM64694.1 - 3.2e-14 54.1 0.1 6.1e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM64694.1 - 7.7e-08 32.2 0.1 1.6e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KUM64694.1 - 0.049 13.9 0.1 0.093 13.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain SIS_2 PF13580.6 KUM64694.1 - 0.17 11.9 1.9 8.1 6.5 0.0 2.3 1 1 0 2 2 2 0 SIS domain AlaDh_PNT_C PF01262.21 KUM64694.1 - 0.21 10.9 3.6 0.4 10.0 3.6 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF5049 PF16468.5 KUM64694.1 - 0.22 11.5 0.1 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5049) Dynactin_p22 PF07426.11 KUM64695.1 - 6.8e-10 39.1 0.0 1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 SlyX PF04102.12 KUM64695.1 - 0.041 14.5 2.2 9.4 6.9 0.3 3.2 3 0 0 3 3 3 0 SlyX Dynamitin PF04912.14 KUM64695.1 - 0.058 12.7 0.4 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 Dynamitin DivIC PF04977.15 KUM64695.1 - 0.11 12.3 0.1 0.71 9.7 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF1143 PF06608.11 KUM64696.1 - 0.032 14.3 0.0 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1143) ACC_epsilon PF13822.6 KUM64696.1 - 0.18 12.5 3.1 7.3 7.4 0.3 2.1 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Laterosporulin PF17861.1 KUM64696.1 - 0.2 12.1 0.0 23 5.5 0.0 2.2 2 0 0 2 2 2 0 Laterosporulin defensin-like peptide Pkinase PF00069.25 KUM64697.1 - 1.9e-20 73.4 0.1 7.5e-20 71.4 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM64697.1 - 1.1e-13 51.1 0.0 1.2e-11 44.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase AA_permease PF00324.21 KUM64698.1 - 8.5e-17 60.9 9.2 8.4e-16 57.6 9.2 2.2 1 1 0 1 1 1 1 Amino acid permease Metallophos PF00149.28 KUM64699.1 - 1.3e-10 42.1 0.0 1.9e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KUM64699.1 - 3e-05 24.3 0.0 0.00012 22.4 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KUM64699.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily FAD_binding_4 PF01565.23 KUM64700.1 - 6.6e-24 84.2 1.3 1.2e-23 83.4 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KUM64700.1 - 2.9e-13 49.7 2.4 5.2e-13 48.9 2.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like CoA_binding_2 PF13380.6 KUM64700.1 - 0.15 12.5 0.1 0.53 10.8 0.1 1.9 1 1 0 1 1 1 0 CoA binding domain Pkinase PF00069.25 KUM64702.1 - 4e-64 216.5 0.0 4.8e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM64702.1 - 1.4e-36 126.1 0.0 1.8e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KUM64702.1 - 0.0037 16.3 0.0 0.0054 15.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KUM64702.1 - 0.021 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KUM64702.1 - 0.021 14.8 0.1 0.12 12.3 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KUM64702.1 - 0.064 12.3 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KUM64702.1 - 0.12 11.2 0.0 0.3 9.8 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 KUM64702.1 - 0.14 11.8 0.1 0.88 9.1 0.1 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Abhydrolase_1 PF00561.20 KUM64704.1 - 1.7e-47 162.2 0.0 7.1e-47 160.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KUM64704.1 - 0.00092 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase zf-RING_6 PF14835.6 KUM64704.1 - 0.2 11.6 0.3 0.43 10.5 0.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Glyco_hydro_43 PF04616.14 KUM64705.1 - 5.3e-33 114.6 0.1 9.5e-33 113.7 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KUM64705.1 - 2.9e-05 23.8 0.7 0.00043 19.9 0.3 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Gly_transf_sug PF04488.15 KUM64706.1 - 4.4e-13 49.7 0.0 7.8e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif PEMT PF04191.13 KUM64706.1 - 0.22 12.0 0.4 1.2 9.6 0.0 2.3 3 0 0 3 3 3 0 Phospholipid methyltransferase Syndecan PF01034.20 KUM64707.1 - 6.2 6.8 6.8 1.8 8.6 1.6 2.6 2 0 0 2 2 2 0 Syndecan domain CNH PF00780.22 KUM64708.1 - 3.4e-81 272.9 0.0 7.5e-81 271.8 0.0 1.6 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 KUM64708.1 - 1.5e-43 148.1 0.0 3.4e-43 147.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KUM64708.1 - 1.4e-37 129.7 0.0 2.7e-37 128.8 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KUM64708.1 - 2.7e-12 46.6 0.0 6.8e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP-synt_C PF00137.21 KUM64709.1 - 1.5e-26 92.5 38.0 4.4e-17 62.2 13.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Spermine_synth PF01564.17 KUM64710.1 - 3.9e-09 36.2 0.0 6.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_30 PF05430.11 KUM64710.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase YbhQ PF11076.8 KUM64710.1 - 0.1 12.6 0.2 0.21 11.6 0.2 1.4 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ EmrE PF13536.6 KUM64710.1 - 0.11 12.0 4.3 0.1 12.2 2.5 1.7 2 0 0 2 2 2 0 Putative multidrug resistance efflux transporter Jiraiya PF15038.6 KUM64710.1 - 1.6 8.2 4.4 10 5.5 2.2 2.2 2 0 0 2 2 2 0 Jiraiya DLIC PF05783.11 KUM64711.1 - 2.4e-37 128.9 0.0 7.7e-36 123.9 0.0 2.5 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) AMP-binding PF00501.28 KUM64712.1 - 7.7e-94 314.7 0.0 9.7e-94 314.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM64712.1 - 3.1e-18 66.5 0.0 6.9e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2052 PF09747.9 KUM64713.1 - 2e-17 64.0 15.0 3.2e-09 37.2 13.3 2.1 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) Septin PF00735.18 KUM64715.1 - 2.6e-107 358.3 0.2 5.1e-107 357.3 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KUM64715.1 - 1.9e-05 24.7 0.0 5.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KUM64715.1 - 0.0018 18.2 2.5 0.0061 16.5 0.1 2.7 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KUM64715.1 - 0.0023 17.5 0.2 0.19 11.3 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KUM64715.1 - 0.02 15.0 5.1 1.6 8.8 0.0 3.0 2 1 1 3 3 3 0 Dynamin family IIGP PF05049.13 KUM64715.1 - 0.061 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 KUM64715.1 - 0.081 13.2 0.0 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain EB1 PF03271.17 KUM64715.1 - 0.2 11.9 3.4 2.8 8.2 0.9 2.6 2 0 0 2 2 2 0 EB1-like C-terminal motif RRM_1 PF00076.22 KUM64716.1 - 2.1e-19 69.1 0.0 5.4e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KUM64716.1 - 7.4e-06 26.0 0.0 2.2e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif RR_TM4-6 PF06459.12 KUM64716.1 - 2.3 8.0 14.7 3.3 7.5 14.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FUSC PF04632.12 KUM64716.1 - 6.3 5.2 5.2 8.2 4.8 5.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family WD40 PF00400.32 KUM64717.1 - 2.6e-07 31.2 0.1 0.09 13.7 0.0 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Nbas_N PF15492.6 KUM64717.1 - 0.00023 20.6 0.0 0.025 13.9 0.0 2.4 1 1 1 2 2 2 2 Neuroblastoma-amplified sequence, N terminal ANAPC4_WD40 PF12894.7 KUM64717.1 - 0.00024 21.4 0.0 0.013 15.8 0.0 3.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KUM64717.1 - 0.005 15.8 0.0 0.12 11.3 0.0 2.1 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KUM64717.1 - 0.058 11.4 0.0 0.1 10.5 0.0 1.4 1 1 0 1 1 1 0 IKI3 family Frtz PF11768.8 KUM64717.1 - 0.21 9.9 0.0 0.3 9.3 0.0 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz CH PF00307.31 KUM64718.1 - 9.1e-46 154.5 0.0 2.6e-21 75.8 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KUM64718.1 - 1e-20 73.6 0.0 2.9e-20 72.1 0.0 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KUM64718.1 - 1e-08 34.9 0.3 6.8e-05 22.6 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 KUM64718.1 - 0.00027 20.6 0.1 0.0015 18.3 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KUM64718.1 - 0.0031 17.0 0.0 0.036 13.6 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KUM64718.1 - 0.0045 16.8 0.1 0.036 13.9 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair FliG_N PF14842.6 KUM64718.1 - 0.16 12.5 0.2 12 6.5 0.0 2.7 1 1 1 2 2 2 0 FliG N-terminal domain EF-hand_7 PF13499.6 KUM64718.1 - 0.2 12.1 2.9 0.61 10.6 0.1 3.1 3 0 0 3 3 3 0 EF-hand domain pair RRM_1 PF00076.22 KUM64719.1 - 1.2e-14 53.8 0.0 2e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KUM64719.1 - 7.5e-06 26.4 34.7 1.1e-05 25.9 10.8 4.4 3 1 1 4 4 4 2 C-terminal duplication domain of Friend of PRMT1 WD40 PF00400.32 KUM64720.1 - 8.1e-21 74.0 12.6 3.1e-07 31.0 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM64720.1 - 7.7e-08 32.5 0.2 0.15 12.4 0.0 4.4 2 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KUM64720.1 - 0.0013 17.8 0.2 0.21 10.5 0.0 2.6 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 KUM64720.1 - 0.0023 16.8 0.0 0.14 11.0 0.0 2.1 2 0 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) Cytochrom_D1 PF02239.16 KUM64720.1 - 0.0071 14.9 0.0 0.012 14.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain dsrm PF00035.26 KUM64720.1 - 0.1 13.3 0.0 0.31 11.8 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif PUL PF08324.11 KUM64721.1 - 1.8e-76 257.0 0.3 2.7e-76 256.4 0.3 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KUM64721.1 - 2.1e-45 153.6 0.1 4e-45 152.7 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KUM64721.1 - 6.5e-33 112.2 11.0 2.8e-07 31.1 1.9 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 KUM64721.1 - 0.003 17.6 0.0 0.22 11.6 0.0 2.8 1 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region YjeF_N PF03853.15 KUM64722.1 - 2.3e-23 82.9 0.0 5.8e-23 81.6 0.0 1.5 1 1 1 2 2 2 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.19 KUM64723.1 - 1.2e-24 86.1 0.1 1.9e-24 85.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 RRM_1 PF00076.22 KUM64724.1 - 9.5e-17 60.6 0.0 2.7e-14 52.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KUM64724.1 - 0.053 13.4 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Bot1p PF12298.8 KUM64725.1 - 4.3e-51 173.5 0.3 4.3e-51 173.5 0.3 1.6 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Glyco_hydro_31 PF01055.26 KUM64727.1 - 4.5e-144 480.9 3.5 6.4e-144 480.4 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KUM64727.1 - 1.1e-36 125.5 0.0 2.2e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KUM64727.1 - 1.5e-12 47.7 1.2 1.5e-12 47.7 1.2 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like MARVEL PF01284.23 KUM64729.1 - 8.4e-18 64.8 10.7 1.1e-17 64.4 10.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain MHYT PF03707.16 KUM64729.1 - 4.5 7.5 8.4 2.2 8.5 1.8 3.0 2 1 0 2 2 2 0 Bacterial signalling protein N terminal repeat LCCL PF03815.19 KUM64730.1 - 1.6e-20 73.0 0.0 2.7e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 LCCL domain ADH_zinc_N PF00107.26 KUM64731.1 - 0.075 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Oxidored_FMN PF00724.20 KUM64732.1 - 1.1e-86 291.3 0.0 1.2e-86 291.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Thiolase_N PF00108.23 KUM64733.1 - 0.0038 16.6 2.8 0.029 13.7 0.2 1.9 1 1 0 2 2 2 2 Thiolase, N-terminal domain ThiF PF00899.21 KUM64734.1 - 2.2e-41 141.8 0.0 3.7e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KUM64734.1 - 0.002 18.4 0.2 0.023 14.9 0.2 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KUM64734.1 - 0.0039 17.4 0.0 0.013 15.8 0.0 1.9 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KUM64734.1 - 0.029 13.9 0.1 0.053 13.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Melibiase_2 PF16499.5 KUM64734.1 - 0.037 13.2 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha galactosidase A ApbA PF02558.16 KUM64734.1 - 0.042 13.5 0.1 0.077 12.6 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KUM64734.1 - 0.067 13.6 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding PNP_UDP_1 PF01048.20 KUM64737.1 - 7.9e-07 28.6 1.5 9e-06 25.1 1.5 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.6 KUM64737.1 - 9e-05 22.9 0.0 0.00017 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KUM64737.1 - 0.012 14.8 0.0 0.051 12.8 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 KUM64737.1 - 0.073 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Phage_T4_Ndd PF06591.11 KUM64737.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) Fungal_trans PF04082.18 KUM64738.1 - 5.8e-06 25.5 0.0 9.4e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KUM64739.1 - 4.7e-25 88.2 30.9 4.7e-25 88.2 30.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM64739.1 - 1.5e-06 27.4 11.0 1.5e-06 27.4 11.0 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 KUM64739.1 - 0.0041 15.6 8.9 0.0072 14.8 8.9 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector DUF2418 PF10332.9 KUM64739.1 - 0.11 13.0 0.2 0.54 10.8 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) DUF4231 PF14015.6 KUM64739.1 - 0.39 11.2 0.0 0.39 11.2 0.0 3.4 2 1 1 4 4 4 0 Protein of unknown function (DUF4231) AMP-binding PF00501.28 KUM64740.1 - 3.2e-61 207.2 0.0 4.8e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KUM64740.1 - 1e-10 41.8 0.1 4.2e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 KUM64740.1 - 1.1e-10 42.1 0.0 3.4e-10 40.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM64740.1 - 1.2e-08 35.4 0.0 3.9e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Thioesterase PF00975.20 KUM64740.1 - 1.8e-07 31.5 0.0 3.3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KUM64740.1 - 2.4e-06 28.3 0.8 8.6e-06 26.5 0.8 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_12 PF08242.12 KUM64740.1 - 1.1e-05 26.1 0.0 2.8e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding_C PF13193.6 KUM64740.1 - 3.8e-05 24.6 0.0 0.00015 22.6 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.6 KUM64740.1 - 0.00014 21.7 0.0 0.00037 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_1 PF00561.20 KUM64740.1 - 0.00075 19.2 0.4 0.0017 18.0 0.2 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2755 PF10954.8 KUM64740.1 - 0.062 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) MTS PF05175.14 KUM64740.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Abhydrolase_3 PF07859.13 KUM64740.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.16 KUM64742.1 - 1.2e-43 149.4 39.4 1.2e-43 149.4 39.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM64742.1 - 1e-08 34.5 23.1 1.1e-07 31.1 23.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KUM64742.1 - 1.8e-08 34.1 6.3 1.8e-08 34.1 6.3 2.4 2 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Mobilization_B PF17511.2 KUM64742.1 - 0.31 11.4 1.0 0.58 10.5 1.0 1.4 1 0 0 1 1 1 0 Mobilization protein B OATP PF03137.20 KUM64742.1 - 1.8 6.8 15.0 0.24 9.6 6.8 2.6 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Mem_trans PF03547.18 KUM64743.1 - 8.9e-06 24.3 10.0 0.0017 16.8 0.1 3.0 2 1 0 2 2 2 2 Membrane transport protein HpcH_HpaI PF03328.14 KUM64744.1 - 3.5e-35 121.1 0.0 4.4e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family RTTN_N PF14726.6 KUM64746.1 - 0.043 14.6 1.9 4.8 8.0 0.1 2.7 2 1 1 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning DUF4334 PF14232.6 KUM64747.1 - 9.5e-25 86.3 0.3 1.5e-24 85.7 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4334) GXWXG PF14231.6 KUM64747.1 - 2.5e-20 72.3 0.1 4.5e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 GXWXG protein TrkH PF02386.16 KUM64748.1 - 2.5e-148 494.7 10.6 2.3e-146 488.2 4.4 2.1 2 0 0 2 2 2 2 Cation transport protein CN_hydrolase PF00795.22 KUM64749.1 - 2.8e-35 121.9 0.0 5.6e-35 120.9 0.0 1.5 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase ADH_N PF08240.12 KUM64750.1 - 0.0002 21.2 0.0 0.00099 19.0 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM64750.1 - 0.041 13.9 0.1 0.07 13.1 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KUM64750.1 - 0.048 13.6 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Dynamin_M PF01031.20 KUM64751.1 - 1.2e-101 339.7 0.1 1.2e-101 339.7 0.1 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KUM64751.1 - 1.3e-56 191.3 0.1 2.8e-56 190.2 0.1 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KUM64751.1 - 1.2e-30 105.5 4.3 1.2e-30 105.5 4.3 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KUM64751.1 - 1.7e-05 24.8 0.4 0.00016 21.7 0.4 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KUM64751.1 - 0.019 14.7 2.2 4.2 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain WD40 PF00400.32 KUM64756.1 - 5.7e-22 77.6 17.0 5.8e-05 23.8 0.2 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM64756.1 - 3.3e-13 49.7 2.6 0.07 13.4 0.1 5.6 3 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KUM64756.1 - 0.002 17.1 3.7 0.67 8.9 0.3 3.5 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KUM64756.1 - 0.0039 15.9 0.1 0.011 14.4 0.1 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 CLTH PF10607.9 KUM64756.1 - 0.0052 16.7 0.1 0.0093 15.9 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain WD40_3 PF15911.5 KUM64756.1 - 0.0078 16.2 0.1 0.3 11.1 0.0 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat IKI3 PF04762.12 KUM64756.1 - 0.047 11.7 0.2 0.47 8.4 0.0 2.4 2 1 0 2 2 2 0 IKI3 family Frtz PF11768.8 KUM64756.1 - 0.098 11.0 0.1 1.3 7.3 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF4221 PF13970.6 KUM64756.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) WD40_like PF17005.5 KUM64756.1 - 0.15 11.3 0.1 0.41 9.9 0.0 1.7 2 0 0 2 2 2 0 WD40-like domain DUF3449 PF11931.8 KUM64757.1 - 2.4e-74 249.2 0.3 5.8e-74 247.9 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KUM64757.1 - 5.4e-26 90.9 1.0 1.2e-25 89.9 0.1 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KUM64757.1 - 1.1e-15 57.1 0.8 2.7e-15 55.9 0.8 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KUM64757.1 - 1.3e-07 31.7 5.5 1.1e-05 25.6 1.5 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KUM64757.1 - 2.4e-07 30.8 5.1 1.7e-06 28.2 1.0 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding PRP9_N PF16958.5 KUM64757.1 - 5.2e-07 29.8 10.1 0.00026 21.0 3.3 3.0 1 1 1 2 2 2 2 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_2 PF12756.7 KUM64757.1 - 0.0018 18.6 1.4 0.032 14.6 0.1 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) CmlA_N PF18456.1 KUM64757.1 - 0.067 12.5 0.2 0.15 11.4 0.2 1.5 1 0 0 1 1 1 0 Diiron non-heme beta-hydroxylase N-terminal domain DUF4081 PF13312.6 KUM64757.1 - 0.11 12.7 0.4 2.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4081) zf-HYPF PF07503.12 KUM64757.1 - 0.12 12.2 0.1 0.34 10.7 0.1 1.8 1 0 0 1 1 1 0 HypF finger Hrs_helical PF12210.8 KUM64757.1 - 0.25 11.9 5.9 3.9 8.1 0.0 3.0 3 0 0 3 3 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate zf-C2H2_4 PF13894.6 KUM64757.1 - 0.34 11.8 2.2 19 6.5 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C4H2 PF10146.9 KUM64757.1 - 0.76 10.0 6.3 0.065 13.5 0.5 2.0 2 0 0 2 2 2 0 Zinc finger-containing protein DEAD PF00270.29 KUM64758.1 - 2.8e-41 141.2 0.2 4.9e-41 140.4 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM64758.1 - 1.6e-33 115.3 0.1 6.6e-33 113.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KUM64758.1 - 0.0011 18.7 0.1 0.0017 18.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KUM64758.1 - 0.0046 17.0 0.0 0.009 16.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KUM64758.1 - 0.0088 16.4 0.1 0.074 13.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 KUM64758.1 - 0.056 13.4 0.5 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 KUM64758.1 - 0.089 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 KUM64758.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 KUM64758.1 - 0.18 12.1 0.6 0.73 10.1 0.6 1.9 1 1 0 1 1 1 0 AAA domain Ras PF00071.22 KUM64759.1 - 7.1e-42 142.8 0.0 9.6e-42 142.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM64759.1 - 9.8e-14 51.6 0.0 2.5e-13 50.3 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KUM64759.1 - 0.0013 18.8 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KUM64759.1 - 0.0059 16.9 0.0 0.04 14.2 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KUM64759.1 - 0.065 13.6 0.0 0.079 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KUM64759.1 - 0.075 12.9 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 KUM64759.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 KUM64759.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KUM64759.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KUM64759.1 - 0.17 12.0 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Hemerythrin PF01814.23 KUM64762.1 - 8.1e-15 55.6 0.1 1.1e-14 55.2 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Alpha_kinase PF02816.18 KUM64762.1 - 0.11 12.6 0.3 0.14 12.3 0.3 1.2 1 0 0 1 1 1 0 Alpha-kinase family CTD_bind PF04818.13 KUM64762.1 - 0.15 12.9 0.1 0.53 11.1 0.1 1.9 1 1 0 1 1 1 0 RNA polymerase II-binding domain. A_deaminase PF00962.22 KUM64763.1 - 6.6e-22 78.3 0.0 1.8e-21 76.8 0.0 1.8 1 1 0 1 1 1 1 Adenosine/AMP deaminase ATP-synt_ab PF00006.25 KUM64764.1 - 1.4e-109 364.7 0.0 2e-109 364.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KUM64764.1 - 8.9e-46 154.7 0.0 1.7e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KUM64764.1 - 1.2e-11 44.9 4.1 8.2e-10 39.1 0.4 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KUM64764.1 - 0.041 13.1 0.1 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain SCAN PF02023.17 KUM64765.1 - 0.072 12.9 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 SCAN domain NAC PF01849.18 KUM64766.1 - 4.7e-22 77.7 0.0 8.8e-21 73.6 0.0 2.2 2 0 0 2 2 2 1 NAC domain NESP55 PF06390.12 KUM64766.1 - 0.0068 16.0 4.4 0.0068 16.0 4.4 1.9 2 0 0 2 2 2 1 Neuroendocrine-specific golgi protein P55 (NESP55) CENP-B_dimeris PF09026.10 KUM64766.1 - 0.034 14.5 3.7 15 6.1 5.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4578 PF15147.6 KUM64766.1 - 0.13 13.2 0.4 0.24 12.3 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) Ribosomal_L14e PF01929.17 KUM64767.1 - 4.4e-26 91.2 0.2 7.7e-26 90.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KUM64767.1 - 2.8e-07 30.2 0.2 5.1e-07 29.4 0.2 1.4 1 0 0 1 1 1 1 KOW motif YIF1 PF03878.15 KUM64768.1 - 3.2e-98 328.0 3.3 3.8e-98 327.8 3.3 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KUM64768.1 - 5.5e-05 22.9 6.3 5.5e-05 22.9 6.3 1.5 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.13 KUM64769.1 - 1.7e-77 261.2 0.0 2.3e-77 260.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KUM64769.1 - 1.8e-50 171.3 0.0 3.3e-50 170.5 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KUM64769.1 - 1.3e-09 38.1 0.0 4.1e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KUM64769.1 - 2.1e-07 30.2 0.0 3.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KUM64769.1 - 0.00044 20.0 0.0 0.00083 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KUM64769.1 - 0.0035 17.1 0.1 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KUM64769.1 - 0.013 15.8 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 KUM64769.1 - 0.019 15.0 0.0 0.095 12.8 0.0 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 KUM64769.1 - 0.054 13.6 0.1 0.49 10.5 0.1 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_31 PF13614.6 KUM64769.1 - 0.058 13.3 0.1 0.44 10.4 0.0 2.0 1 1 1 2 2 2 0 AAA domain Fer4_NifH PF00142.18 KUM64769.1 - 0.08 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ABC_tran PF00005.27 KUM64769.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 KUM64769.1 - 0.11 12.9 0.0 0.45 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Aldedh PF00171.22 KUM64770.1 - 9e-120 400.3 0.0 1.1e-119 400.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAM217 PF15344.6 KUM64772.1 - 0.33 10.8 1.8 0.55 10.1 1.8 1.3 1 0 0 1 1 1 0 FAM217 family Mt_ATP-synt_D PF05873.12 KUM64773.1 - 1.5e-23 83.4 1.2 1.8e-23 83.1 1.2 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) E3_UbLigase_R4 PF13764.6 KUM64773.1 - 0.023 12.9 0.2 0.026 12.7 0.2 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 CheZ PF04344.13 KUM64773.1 - 0.028 14.3 1.4 0.037 14.0 1.4 1.4 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ T2SSM_b PF10741.9 KUM64773.1 - 0.034 14.0 0.3 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b ATPase PF06745.13 KUM64773.1 - 0.062 12.6 0.3 0.093 12.1 0.3 1.2 1 0 0 1 1 1 0 KaiC DUF2408 PF10303.9 KUM64773.1 - 0.1 13.2 1.4 0.16 12.6 1.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DMPK_coil PF08826.10 KUM64773.1 - 0.12 12.5 2.2 0.18 11.9 0.4 2.1 2 0 0 2 2 2 0 DMPK coiled coil domain like Spectrin PF00435.21 KUM64773.1 - 0.14 12.6 3.9 1.9 9.0 1.3 2.3 1 1 0 2 2 2 0 Spectrin repeat LXG PF04740.12 KUM64773.1 - 0.21 11.3 3.9 0.77 9.4 3.7 1.8 1 1 1 2 2 2 0 LXG domain of WXG superfamily FlaC_arch PF05377.11 KUM64773.1 - 0.25 11.8 2.5 3.3 8.2 0.6 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 KUM64773.1 - 0.61 10.4 2.9 4.2 7.7 0.6 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) GATase_6 PF13522.6 KUM64774.1 - 2e-13 50.7 0.1 6.4e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KUM64774.1 - 9.5e-11 41.7 0.0 1.9e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KUM64774.1 - 3.3e-07 29.9 0.0 9.5e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KUM64774.1 - 4.4e-05 22.5 0.0 0.0001 21.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.6 KUM64774.1 - 0.061 12.8 0.0 0.17 11.3 0.0 1.7 1 1 0 1 1 1 0 Phosphoribosyl transferase DNA_photolyase PF00875.18 KUM64774.1 - 0.15 12.1 0.0 0.47 10.4 0.0 1.8 2 0 0 2 2 2 0 DNA photolyase HhH-GPD PF00730.25 KUM64775.1 - 8.2e-07 29.5 0.0 1.6e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KUM64775.1 - 0.011 15.5 0.0 0.045 13.6 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 KUM64775.1 - 0.017 15.7 0.0 0.21 12.2 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain Sec16_C PF12931.7 KUM64777.1 - 2.6e-105 352.4 0.0 3.7e-105 351.9 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.7 KUM64777.1 - 1.9e-71 241.0 26.1 1.9e-71 241.0 26.1 4.6 3 1 0 3 3 3 2 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.7 KUM64777.1 - 2.1e-34 118.7 0.0 5.1e-34 117.4 0.0 1.8 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Ribosomal_L28e PF01778.17 KUM64778.1 - 1.7e-38 131.9 1.1 3.2e-38 131.0 1.1 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 KUM64778.1 - 1.2e-30 106.0 11.5 1.2e-30 106.0 11.5 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KUM64778.1 - 5.6e-06 26.0 16.3 6.9e-06 25.7 16.3 1.1 1 0 0 1 1 1 1 BUD22 CxC6 PF18721.1 KUM64778.1 - 0.16 12.3 0.4 0.37 11.1 0.2 1.7 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Drc1-Sld2 PF11719.8 KUM64778.1 - 0.95 8.9 11.8 1.3 8.5 11.8 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nop14 PF04147.12 KUM64778.1 - 3.2 5.8 23.1 4.1 5.5 23.1 1.2 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 KUM64778.1 - 3.5 6.3 7.4 4.4 6.0 7.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 KUM64778.1 - 5.4 5.2 18.7 2.2 6.5 14.5 1.9 2 0 0 2 2 2 0 CDC45-like protein TFIIF_alpha PF05793.12 KUM64778.1 - 8.9 4.8 25.3 15 4.1 25.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PhoLip_ATPase_C PF16212.5 KUM64779.1 - 3.4e-47 161.3 9.0 3.4e-47 161.3 9.0 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KUM64779.1 - 7.5e-17 60.8 1.5 1.5e-16 59.8 1.5 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KUM64779.1 - 4.4e-13 50.0 1.7 4e-10 40.3 1.7 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KUM64779.1 - 2.5e-08 33.9 0.0 6.7e-07 29.3 0.0 2.7 3 0 0 3 3 3 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KUM64779.1 - 4.1e-07 29.7 2.7 0.0003 20.4 0.0 3.3 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase_3 PF08282.12 KUM64779.1 - 0.0039 17.0 0.0 0.0085 15.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HIGH_NTase1_ass PF16581.5 KUM64779.1 - 0.098 12.6 0.1 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region Cytochrome-c551 PF10643.9 KUM64779.1 - 1.3 8.5 3.9 25 4.4 0.1 2.5 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 GAS2 PF02187.17 KUM64780.1 - 3.6e-06 27.0 0.1 7.8e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hus1 PF04005.12 KUM64782.1 - 8.8e-103 343.4 0.0 9.9e-103 343.2 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Hexokinase_2 PF03727.16 KUM64783.1 - 3.2e-72 242.8 0.0 4.1e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KUM64783.1 - 1e-63 214.8 0.0 2.1e-63 213.9 0.0 1.5 2 0 0 2 2 2 1 Hexokinase RabGAP-TBC PF00566.18 KUM64785.1 - 6e-41 140.5 1.2 1.2e-40 139.4 1.2 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KUM64785.1 - 1.4e-07 31.2 0.0 0.0093 15.5 0.0 3.3 2 1 0 2 2 2 2 Rab-binding domain (RBD) dCMP_cyt_deam_1 PF00383.23 KUM64786.1 - 2.7e-05 24.0 0.0 3.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KUM64786.1 - 0.05 13.2 0.1 6.1 6.4 0.0 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases E1-E2_ATPase PF00122.20 KUM64787.1 - 2.4e-37 128.2 18.7 1.1e-30 106.5 0.0 4.0 4 1 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KUM64787.1 - 4.1e-26 91.8 8.5 4.1e-26 91.8 8.5 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KUM64787.1 - 1.6e-18 67.8 0.0 3.8e-14 53.5 0.0 3.1 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KUM64787.1 - 2.7e-18 65.4 0.0 5.8e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KUM64787.1 - 1.1e-15 57.4 0.0 2.2e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DctM PF06808.12 KUM64787.1 - 0.00016 20.6 6.4 0.00059 18.8 0.4 2.8 3 0 0 3 3 3 2 Tripartite ATP-independent periplasmic transporter, DctM component Hydrolase_3 PF08282.12 KUM64787.1 - 0.00076 19.3 0.2 0.011 15.5 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DNA_methylase PF00145.17 KUM64788.1 - 7.6e-40 137.3 0.0 1.7e-27 96.7 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase PrmA PF06325.13 KUM64788.1 - 0.23 10.8 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MmgE_PrpD PF03972.14 KUM64789.1 - 8.8e-147 489.2 0.1 1e-146 489.0 0.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF1266 PF06889.11 KUM64789.1 - 0.029 14.4 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) Glyco_hydro_28 PF00295.17 KUM64790.1 - 5.1e-56 190.1 15.8 6.4e-56 189.8 15.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KUM64790.1 - 0.13 12.2 8.9 0.41 10.5 8.7 2.0 1 1 0 1 1 1 0 Right handed beta helix region Pectinesterase PF01095.19 KUM64791.1 - 2e-49 168.0 4.2 2.6e-49 167.5 4.2 1.1 1 0 0 1 1 1 1 Pectinesterase Pectate_lyase_3 PF12708.7 KUM64791.1 - 0.0012 18.7 3.1 0.002 18.0 3.1 1.4 1 0 0 1 1 1 1 Pectate lyase superfamily protein Fig1 PF12351.8 KUM64793.1 - 6e-51 173.1 6.0 6e-51 173.1 6.0 1.4 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 CorA PF01544.18 KUM64794.1 - 1.2e-08 34.7 3.2 1.2e-08 34.7 3.2 2.9 4 0 0 4 4 4 1 CorA-like Mg2+ transporter protein DUF4611 PF15387.6 KUM64794.1 - 0.14 12.3 1.9 0.4 10.9 1.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.12 KUM64794.1 - 0.48 10.1 4.5 0.82 9.4 4.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein 4HB_MCP_1 PF12729.7 KUM64794.1 - 0.97 8.9 3.1 2.9 7.4 3.1 1.8 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction CENP-B_dimeris PF09026.10 KUM64794.1 - 7.5 7.0 9.0 16 5.9 9.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCIP PF13324.6 KUM64794.1 - 8.1 6.0 8.8 0.69 9.5 2.2 2.5 3 0 0 3 3 3 0 Grap2 and cyclin-D-interacting Abhydrolase_3 PF07859.13 KUM64796.1 - 1.1e-35 123.4 0.0 1.5e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KUM64796.1 - 0.00019 20.4 0.0 0.0024 16.8 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family DLH PF01738.18 KUM64796.1 - 0.0027 17.3 0.0 0.034 13.7 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KUM64796.1 - 0.0037 16.8 0.0 0.0063 16.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 KUM64796.1 - 0.0051 15.5 0.0 0.0076 15.0 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 KUM64796.1 - 0.0057 16.5 0.0 0.0091 15.8 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase G0-G1_switch_2 PF15103.6 KUM64797.1 - 0.0017 18.7 0.0 0.0029 18.0 0.0 1.4 1 0 0 1 1 1 1 G0/G1 switch protein 2 Vma12 PF11712.8 KUM64797.1 - 0.08 13.0 3.7 0.15 12.2 3.7 1.7 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4389 PF14333.6 KUM64797.1 - 0.085 12.8 0.4 0.085 12.8 0.4 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4389) DUF2157 PF09925.9 KUM64797.1 - 1.9 8.3 9.5 17 5.2 9.4 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) ADH_N PF08240.12 KUM64798.1 - 1.7e-09 37.5 0.3 1.1e-08 34.9 0.3 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM64798.1 - 2.9e-09 37.0 0.1 5.2e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM64798.1 - 0.077 14.0 0.0 0.16 13.0 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Mso1_Sec1_bdg PF14475.6 KUM64799.1 - 4.2e-13 48.6 0.0 7.4e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Rieske PF00355.26 KUM64801.1 - 3.2e-17 62.2 0.0 5.7e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 KUM64802.1 - 3.9e-23 82.5 1.1 5.8e-11 42.8 0.0 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Polysacc_lyase PF14099.6 KUM64803.1 - 4e-56 190.2 10.0 4.5e-56 190.0 10.0 1.0 1 0 0 1 1 1 1 Polysaccharide lyase DUF1080 PF06439.11 KUM64803.1 - 0.00041 20.5 5.6 0.00059 20.0 5.0 1.5 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1080) Ank_2 PF12796.7 KUM64804.1 - 3.5e-05 24.3 0.0 0.00083 19.9 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KUM64804.1 - 0.00041 20.6 0.3 5.7 7.8 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat F-box PF00646.33 KUM64806.1 - 0.035 14.0 0.1 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 F-box domain MFS_1 PF07690.16 KUM64808.1 - 1.1e-36 126.6 19.8 1.6e-27 96.3 0.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM64808.1 - 5.5e-10 38.7 9.5 8.6e-09 34.8 0.4 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 KUM64808.1 - 0.00012 21.5 1.1 0.00012 21.5 1.1 2.7 2 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KUM64808.1 - 0.00088 18.2 5.4 0.00088 18.2 5.4 2.9 2 1 1 3 3 3 2 MFS_1 like family ANAPC4_WD40 PF12894.7 KUM64811.1 - 0.059 13.7 0.0 0.18 12.2 0.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain BSD PF03909.17 KUM64814.1 - 5.8e-20 71.0 1.3 1.2e-19 70.0 1.3 1.6 1 0 0 1 1 1 1 BSD domain KH_1 PF00013.29 KUM64817.1 - 1.3e-44 149.9 2.9 2.3e-17 62.6 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KUM64817.1 - 1.6e-12 47.1 2.2 0.0046 16.8 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KUM64817.1 - 1.7e-06 27.8 0.1 0.68 9.9 0.1 3.3 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KUM64817.1 - 9.7e-05 22.3 0.0 0.02 14.9 0.0 2.5 2 0 0 2 2 2 2 KH-like RNA-binding domain KH_5 PF13184.6 KUM64817.1 - 9.7e-05 22.4 7.0 0.32 11.1 0.2 3.3 3 0 0 3 3 3 2 NusA-like KH domain Proteasome PF00227.26 KUM64818.1 - 5.6e-45 153.2 0.1 7.3e-45 152.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KUM64818.1 - 2.9e-13 48.9 0.4 2.9e-13 48.9 0.4 1.9 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Methyltransf_23 PF13489.6 KUM64819.1 - 1.1e-21 77.4 0.0 3.1e-21 75.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM64819.1 - 4.6e-08 33.7 0.0 2.1e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM64819.1 - 8.2e-06 25.7 0.0 5.8e-05 22.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM64819.1 - 2.6e-05 24.9 0.0 0.00014 22.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM64819.1 - 8e-05 23.2 0.0 0.00027 21.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KUM64819.1 - 0.017 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KUM64819.1 - 0.02 14.2 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 KUM64819.1 - 0.024 14.1 0.0 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 KUM64819.1 - 0.079 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 KUM64819.1 - 0.12 11.7 0.0 0.34 10.2 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 KUM64820.1 - 0.00056 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF4470 PF14737.6 KUM64821.1 - 1.2e-21 76.7 0.0 2.7e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) CH PF00307.31 KUM64822.1 - 0.043 14.0 0.1 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 Calponin homology (CH) domain KAR9 PF08580.10 KUM64823.1 - 4.5e-230 765.8 6.4 4.5e-230 765.8 6.4 1.9 2 1 0 2 2 2 1 Yeast cortical protein KAR9 DNA_photolyase PF00875.18 KUM64823.1 - 0.042 13.9 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 DNA photolyase PilJ PF13675.6 KUM64823.1 - 0.074 13.1 2.5 1.5 8.8 0.1 3.7 4 0 0 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term FAA_hydro_N_2 PF18288.1 KUM64823.1 - 0.074 13.5 0.3 0.28 11.6 0.3 2.0 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 NPV_P10 PF05531.12 KUM64823.1 - 0.23 11.9 5.3 0.2 12.2 0.9 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4685 PF15737.5 KUM64823.1 - 0.55 10.7 3.9 2.6 8.5 0.4 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4685) Acetyltransf_1 PF00583.25 KUM64824.1 - 1.2e-07 32.0 0.0 1.6e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KUM64824.1 - 2.7e-06 28.1 0.0 3.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KUM64824.1 - 0.00012 22.4 0.0 0.00021 21.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KUM64824.1 - 0.0029 17.7 0.0 0.0042 17.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KUM64824.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.7 KUM64824.1 - 0.058 13.3 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR_2 PF13233.6 KUM64825.1 - 8.5e-21 74.5 0.3 1.2e-20 74.0 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KUM64825.1 - 2.1e-10 40.5 0.1 3.5e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MBOAT PF03062.19 KUM64827.1 - 4.6e-40 138.0 17.2 1.1e-33 117.0 3.2 2.6 3 0 0 3 3 3 2 MBOAT, membrane-bound O-acyltransferase family Cortexin PF11057.8 KUM64827.1 - 0.022 14.6 1.0 0.84 9.5 0.0 3.3 3 0 0 3 3 3 0 Cortexin of kidney CoA_binding_3 PF13727.6 KUM64827.1 - 0.79 9.7 7.5 1.4 8.9 1.3 3.3 3 0 0 3 3 3 0 CoA-binding domain Acylphosphatase PF00708.18 KUM64828.1 - 7.9e-24 83.9 0.3 9.8e-24 83.6 0.3 1.1 1 0 0 1 1 1 1 Acylphosphatase AOX PF01786.17 KUM64829.1 - 1.1e-98 329.2 0.0 1.3e-98 328.9 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase AFP PF02420.15 KUM64831.1 - 3.6e-06 26.6 1.0 4.3 8.0 0.0 4.3 4 0 0 4 4 4 2 Insect antifreeze protein repeat YqgC PF17430.2 KUM64831.1 - 0.001 19.1 1.5 1.1 9.4 0.2 3.7 1 1 2 3 3 3 1 Uncharacterized YqgC-like DLEU7 PF15760.5 KUM64831.1 - 0.074 12.5 0.2 0.095 12.2 0.2 1.1 1 0 0 1 1 1 0 Leukemia-associated protein 7 zf-CCHC PF00098.23 KUM64831.1 - 2.6 8.2 10.5 9 6.6 0.3 4.0 4 0 0 4 4 4 0 Zinc knuckle DUF1478 PF07349.11 KUM64833.1 - 0.0017 18.3 1.1 0.26 11.2 0.2 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF1478) DUF1576 PF07613.11 KUM64833.1 - 0.0021 17.6 0.8 5 6.6 0.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1576) Rbx_binding PF18113.1 KUM64833.1 - 0.0032 17.2 0.1 0.3 10.9 0.0 2.2 1 1 2 3 3 3 2 Rubredoxin binding C-terminal domain Phage-MuB_C PF09077.11 KUM64833.1 - 0.0049 16.7 0.0 9.4 6.2 0.0 3.0 3 0 0 3 3 3 2 Mu B transposition protein, C terminal DUF717 PF05338.12 KUM64833.1 - 0.023 14.8 0.0 11 6.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF717) DUF3389 PF11869.8 KUM64833.1 - 0.14 12.4 1.8 44 4.4 0.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3389) CLN3 PF02487.17 KUM64835.1 - 0.0012 18.0 5.8 0.0013 17.9 5.8 1.0 1 0 0 1 1 1 1 CLN3 protein Connexin PF00029.19 KUM64835.1 - 0.0012 18.7 11.5 0.0014 18.5 11.5 1.2 1 0 0 1 1 1 1 Connexin Perilipin PF03036.16 KUM64835.1 - 0.0025 16.9 6.6 0.0027 16.8 6.6 1.1 1 0 0 1 1 1 1 Perilipin family Atrophin-1 PF03154.15 KUM64835.1 - 0.0053 15.1 5.2 0.0055 15.1 5.2 1.1 1 0 0 1 1 1 1 Atrophin-1 family RPN2_C PF18004.1 KUM64835.1 - 0.0063 16.5 23.6 0.0079 16.1 23.6 1.1 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain Rrn6 PF10214.9 KUM64835.1 - 0.012 14.2 5.6 0.013 14.0 5.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Ctr PF04145.15 KUM64835.1 - 0.013 16.1 2.1 0.019 15.6 2.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF3807 PF12720.7 KUM64835.1 - 0.015 15.6 14.9 0.018 15.4 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SET PF00856.28 KUM64835.1 - 0.018 15.4 1.5 0.022 15.2 1.5 1.1 1 0 0 1 1 1 0 SET domain DDHD PF02862.17 KUM64835.1 - 0.022 15.0 6.7 0.024 14.8 6.7 1.1 1 0 0 1 1 1 0 DDHD domain V_ATPase_I PF01496.19 KUM64835.1 - 0.052 11.5 10.1 0.058 11.3 10.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tim54 PF11711.8 KUM64835.1 - 0.062 12.1 14.1 0.072 11.9 14.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 LRIF1 PF15741.5 KUM64835.1 - 0.067 11.7 15.4 0.07 11.7 15.4 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 NPR3 PF03666.13 KUM64835.1 - 0.07 11.9 14.1 0.07 11.9 14.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM176 PF14851.6 KUM64835.1 - 0.071 12.8 6.1 0.086 12.5 6.1 1.2 1 0 0 1 1 1 0 FAM176 family CPSF100_C PF13299.6 KUM64835.1 - 0.072 13.3 11.7 0.087 13.0 11.7 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PAE PF03283.13 KUM64835.1 - 0.073 12.2 4.4 0.092 11.8 4.4 1.2 1 0 0 1 1 1 0 Pectinacetylesterase OATP PF03137.20 KUM64835.1 - 0.079 11.2 5.0 0.082 11.2 5.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4228 PF14009.6 KUM64835.1 - 0.082 13.3 5.5 0.091 13.1 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) RR_TM4-6 PF06459.12 KUM64835.1 - 0.12 12.2 17.3 0.14 12.0 17.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 KUM64835.1 - 0.13 11.3 13.7 0.14 11.2 13.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Vfa1 PF08432.10 KUM64835.1 - 0.16 12.3 24.1 0.2 12.0 24.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GOLD_2 PF13897.6 KUM64835.1 - 0.16 12.5 2.8 0.21 12.1 2.8 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking HSP90 PF00183.18 KUM64835.1 - 0.21 10.5 18.1 0.26 10.1 18.1 1.1 1 0 0 1 1 1 0 Hsp90 protein TMEM214 PF10151.9 KUM64835.1 - 0.24 9.8 15.1 0.25 9.7 15.1 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Serinc PF03348.15 KUM64835.1 - 0.26 10.2 6.2 0.34 9.8 6.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) LYRIC PF15686.5 KUM64835.1 - 0.28 10.7 20.2 0.33 10.5 20.2 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family TERB2 PF15101.6 KUM64835.1 - 0.29 11.1 9.8 0.34 10.9 9.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FHIPEP PF00771.20 KUM64835.1 - 0.29 9.5 3.1 0.34 9.3 3.1 1.1 1 0 0 1 1 1 0 FHIPEP family NEMP PF10225.9 KUM64835.1 - 0.31 10.7 2.8 0.31 10.7 2.8 1.2 1 0 0 1 1 1 0 NEMP family Peptidase_U57 PF05582.12 KUM64835.1 - 0.32 10.2 8.9 0.34 10.1 8.9 1.1 1 0 0 1 1 1 0 YabG peptidase U57 PigN PF04987.14 KUM64835.1 - 0.37 9.6 1.2 0.5 9.2 1.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) RNA_pol_Rpc4 PF05132.14 KUM64835.1 - 0.37 11.2 12.9 0.49 10.8 12.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 SID-1_RNA_chan PF13965.6 KUM64835.1 - 0.38 9.1 6.4 0.39 9.1 6.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 KUM64835.1 - 0.38 9.5 12.8 0.45 9.2 12.8 1.1 1 0 0 1 1 1 0 Presenilin AAA_11 PF13086.6 KUM64835.1 - 0.39 10.5 11.9 0.42 10.4 11.9 1.1 1 0 0 1 1 1 0 AAA domain U79_P34 PF03064.16 KUM64835.1 - 0.39 10.0 18.6 0.46 9.8 18.6 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4604 PF15377.6 KUM64835.1 - 0.41 11.0 23.8 0.56 10.6 23.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) PPL5 PF18168.1 KUM64835.1 - 0.43 9.8 9.6 0.46 9.7 9.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Folate_carrier PF01770.18 KUM64835.1 - 0.45 9.2 7.0 0.57 8.9 7.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF2370 PF10176.9 KUM64835.1 - 0.48 10.0 4.8 0.56 9.8 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) ALMT PF11744.8 KUM64835.1 - 0.51 9.1 13.0 0.58 8.9 13.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter MMU163 PF17119.5 KUM64835.1 - 0.52 9.4 8.5 0.65 9.1 8.5 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Kei1 PF08552.11 KUM64835.1 - 0.55 10.1 1.7 0.71 9.7 1.7 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 EMC3_TMCO1 PF01956.16 KUM64835.1 - 0.57 9.9 10.5 0.67 9.7 10.5 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Mem_trans PF03547.18 KUM64835.1 - 0.77 8.1 4.6 0.86 7.9 4.6 1.0 1 0 0 1 1 1 0 Membrane transport protein MDM10 PF12519.8 KUM64835.1 - 0.78 8.5 10.7 0.79 8.5 10.7 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 MMM1 PF10296.9 KUM64835.1 - 0.88 8.6 8.2 0.95 8.4 8.2 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 DUF2828 PF11443.8 KUM64835.1 - 0.91 7.5 16.5 1.1 7.3 16.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) GNAT_acetyltr_2 PF13718.6 KUM64835.1 - 0.96 8.8 7.0 1.1 8.6 7.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 NARP1 PF12569.8 KUM64835.1 - 1 8.2 23.7 1.2 8.0 23.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CSG2 PF16965.5 KUM64835.1 - 1.1 8.1 5.9 1.3 7.8 5.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator ORC_WH_C PF18137.1 KUM64835.1 - 1.1 9.3 13.7 1.7 8.7 13.7 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal EOS1 PF12326.8 KUM64835.1 - 1.2 9.0 8.7 1.8 8.5 8.7 1.3 1 0 0 1 1 1 0 N-glycosylation protein LicD PF04991.13 KUM64835.1 - 1.3 9.1 13.7 1.5 8.9 13.7 1.1 1 0 0 1 1 1 0 LicD family CDC45 PF02724.14 KUM64835.1 - 1.4 7.1 16.2 1.6 7.0 16.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DcuA_DcuB PF03605.14 KUM64835.1 - 1.5 7.6 2.6 1.7 7.4 2.6 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Nucleoside_tran PF01733.18 KUM64835.1 - 1.6 8.1 3.6 1.9 7.8 3.6 1.1 1 0 0 1 1 1 0 Nucleoside transporter GCD14 PF08704.10 KUM64835.1 - 1.7 8.3 7.9 1.8 8.2 7.9 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Acatn PF13000.7 KUM64835.1 - 1.8 6.9 5.1 2.3 6.6 5.1 1.1 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 FPN1 PF06963.12 KUM64835.1 - 1.9 7.0 7.7 2.7 6.5 7.7 1.5 1 1 0 1 1 1 0 Ferroportin1 (FPN1) Afi1 PF07792.12 KUM64835.1 - 1.9 8.9 17.1 4 7.9 17.1 1.7 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Otopetrin PF03189.13 KUM64835.1 - 2.1 7.0 8.8 2.4 6.9 8.8 1.1 1 0 0 1 1 1 0 Otopetrin Zip PF02535.22 KUM64835.1 - 2.2 7.4 10.0 2.4 7.3 10.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RPOL_N PF14700.6 KUM64835.1 - 2.4 7.5 17.5 2.8 7.3 17.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal O-antigen_lig PF13425.6 KUM64835.1 - 2.5 6.8 12.9 3 6.5 12.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein RNA_polI_A34 PF08208.11 KUM64835.1 - 2.7 8.0 33.7 3.4 7.7 33.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Tho2 PF11262.8 KUM64835.1 - 2.7 7.1 16.2 3.3 6.8 16.2 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Cellulose_synt PF03552.14 KUM64835.1 - 2.8 6.3 6.6 2.8 6.3 6.6 1.1 1 0 0 1 1 1 0 Cellulose synthase Neur_chan_memb PF02932.16 KUM64835.1 - 3.1 7.8 8.9 3.5 7.6 8.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDRGK PF09756.9 KUM64835.1 - 3.3 7.2 31.5 4.3 6.9 31.5 1.1 1 0 0 1 1 1 0 DDRGK domain Rtf2 PF04641.12 KUM64835.1 - 3.5 6.9 23.3 4.7 6.5 23.3 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Sec62 PF03839.16 KUM64835.1 - 3.6 7.1 22.1 4.4 6.8 22.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 MCM_bind PF09739.9 KUM64835.1 - 3.9 5.8 16.3 4.4 5.6 16.3 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor AF-4 PF05110.13 KUM64835.1 - 4.5 5.2 25.7 5.1 5.1 25.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein B12D PF06522.11 KUM64835.1 - 5.3 6.9 9.4 29 4.5 9.4 2.1 1 1 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit TALPID3 PF15324.6 KUM64835.1 - 6 4.4 17.8 6.7 4.2 17.8 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Paramyxo_ncap PF00973.19 KUM64835.1 - 6.8 5.5 11.6 7.5 5.3 11.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Ureide_permease PF07168.11 KUM64835.1 - 7 5.3 8.3 8 5.1 8.3 1.1 1 0 0 1 1 1 0 Ureide permease DUF4407 PF14362.6 KUM64835.1 - 8.3 5.7 9.4 9.9 5.4 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Abhydrolase_1 PF00561.20 KUM64837.1 - 1.5e-13 51.0 0.0 2.7e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM64837.1 - 4.3e-08 32.7 0.0 9.8e-08 31.5 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KUM64837.1 - 0.002 18.7 0.0 0.0034 18.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KUM64837.1 - 0.0059 16.1 0.0 0.029 13.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KUM64837.1 - 0.0092 15.7 0.0 0.015 14.9 0.0 1.5 1 1 0 1 1 1 1 Putative esterase TRI12 PF06609.13 KUM64838.1 - 9.1e-13 47.5 14.9 1.2e-12 47.1 14.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KUM64838.1 - 5.3e-12 45.3 31.2 3.8e-11 42.5 29.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF21 PF01595.20 KUM64838.1 - 0.59 9.8 6.4 2.2 8.0 2.3 2.8 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Dopey_N PF04118.14 KUM64839.1 - 7.9e-116 386.5 0.0 2.3e-115 384.9 0.0 1.8 2 0 0 2 2 2 1 Dopey, N-terminal Mon1 PF03164.14 KUM64840.1 - 1.9e-155 517.9 0.0 2.2e-155 517.7 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 DEAD PF00270.29 KUM64841.1 - 3.1e-21 75.9 0.1 2e-20 73.3 0.0 2.5 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM64841.1 - 4.3e-18 65.7 0.0 1.3e-15 57.7 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RQC PF09382.10 KUM64841.1 - 5.5e-17 61.6 0.0 1.2e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 KUM64841.1 - 2.7e-15 56.9 7.0 7.1e-15 55.5 7.0 1.8 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 KUM64841.1 - 4.4e-07 29.8 0.0 1.2e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 KUM64841.1 - 9.5e-05 22.5 0.0 0.00024 21.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pyridoxal_deC PF00282.19 KUM64842.1 - 9.3e-26 90.4 0.0 1.4e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KUM64842.1 - 0.00012 21.5 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KUM64842.1 - 0.017 14.3 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_5 PF00266.19 KUM64842.1 - 0.019 13.9 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V DUF4110 PF13422.6 KUM64843.1 - 1.2e-32 111.9 3.9 1.2e-32 111.9 3.9 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 KUM64843.1 - 1.7e-26 92.0 13.0 3.5e-07 30.1 0.0 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KUM64843.1 - 1.7e-25 88.7 13.6 1.2e-08 35.0 0.1 6.4 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KUM64843.1 - 4.8e-16 58.4 5.3 8.2e-06 25.7 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KUM64843.1 - 1.4e-14 53.3 6.3 9.7e-05 22.2 0.0 5.9 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 KUM64843.1 - 2.2e-14 53.2 4.9 0.00054 20.2 0.2 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KUM64843.1 - 2.3e-13 49.5 0.1 1.3e-05 24.6 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Bd3614-deam PF14439.6 KUM64843.1 - 3.6 7.7 6.1 40 4.3 0.0 2.4 2 0 0 2 2 2 0 Bd3614-like deaminase DivIC PF04977.15 KUM64844.1 - 0.062 13.1 0.2 0.077 12.8 0.2 1.2 1 0 0 1 1 1 0 Septum formation initiator GIT_CC PF16559.5 KUM64844.1 - 0.13 12.1 0.4 0.42 10.5 0.2 1.8 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Hpt PF01627.23 KUM64845.1 - 0.074 13.3 0.0 1.5 9.1 0.0 2.7 2 0 0 2 2 2 0 Hpt domain DUF1298 PF06974.13 KUM64845.1 - 0.089 12.7 0.1 0.27 11.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) MazG PF03819.17 KUM64845.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain WGG PF10273.9 KUM64847.1 - 3.8e-30 104.4 0.9 6.8e-30 103.6 0.9 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 PDDEXK_10 PF07788.11 KUM64847.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily APH PF01636.23 KUM64851.1 - 2.5e-10 40.7 0.0 4.1e-10 40.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KUM64851.1 - 1.1e-07 31.6 0.2 1.1e-07 31.6 0.2 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KUM64851.1 - 0.0011 17.9 0.0 0.0028 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 KUM64851.1 - 0.0059 16.0 0.2 0.014 14.7 0.0 1.6 2 0 0 2 2 2 1 Ecdysteroid kinase Pox_ser-thr_kin PF05445.11 KUM64851.1 - 0.016 14.2 0.0 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KUM64851.1 - 0.026 13.9 0.1 0.57 9.5 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Med17 PF10156.9 KUM64851.1 - 0.028 13.1 0.4 0.043 12.5 0.4 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex DUF3297 PF11730.8 KUM64851.1 - 0.079 12.9 0.4 0.15 12.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) Ferric_reduct PF01794.19 KUM64853.1 - 2.7e-19 69.5 9.9 2.7e-19 69.5 9.9 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KUM64853.1 - 1.9e-12 47.6 0.0 3.2e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KUM64853.1 - 6.4e-12 45.5 0.0 1.7e-11 44.2 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain SPC25 PF06703.11 KUM64853.1 - 0.11 12.3 0.3 0.34 10.7 0.2 1.9 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) CstA_5TM PF13722.6 KUM64853.1 - 5 7.5 9.9 0.13 12.6 0.9 2.7 3 0 0 3 3 3 0 5TM C-terminal transporter carbon starvation CstA Methyltransf_2 PF00891.18 KUM64854.1 - 4.5e-26 91.4 0.0 1.4e-25 89.8 0.0 1.8 3 0 0 3 3 3 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KUM64854.1 - 5.1e-07 30.4 0.0 1.1e-06 29.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM64854.1 - 2.8e-05 24.0 0.0 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM64854.1 - 2.8e-05 24.7 0.0 7.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM64854.1 - 0.00069 20.2 0.0 0.0014 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KUM64854.1 - 0.0021 17.5 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain MTS PF05175.14 KUM64854.1 - 0.0023 17.5 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KUM64854.1 - 0.034 14.0 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF2431 PF10354.9 KUM64854.1 - 0.1 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Ran-binding PF05508.11 KUM64855.1 - 1.9e-118 395.0 0.2 2.4e-118 394.7 0.2 1.1 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.27 KUM64856.1 - 1.3e-37 129.2 0.0 2e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KUM64856.1 - 3.3e-28 98.2 0.0 6.6e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KUM64856.1 - 0.00034 21.0 0.0 0.00093 19.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KUM64856.1 - 0.012 15.7 0.0 0.039 14.0 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF5035 PF16438.5 KUM64856.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5035) Mfp-3 PF04202.13 KUM64856.1 - 6.3 7.3 11.4 17 5.9 11.4 1.8 1 0 0 1 1 1 0 Foot protein 3 BTB PF00651.31 KUM64857.1 - 1.2e-10 41.5 0.0 2.1e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain MOR2-PAG1_C PF14225.6 KUM64857.1 - 0.045 13.6 0.0 0.095 12.6 0.0 1.5 2 0 0 2 2 2 0 Cell morphogenesis C-terminal Acetyltransf_8 PF13523.6 KUM64858.1 - 9.1e-49 164.9 0.0 1.3e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_12 PF01670.16 KUM64859.1 - 1.3e-43 149.5 4.9 1.8e-43 149.0 4.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Cyclin_N PF00134.23 KUM64860.1 - 1.2e-12 47.7 0.0 7.9e-12 45.0 0.0 2.2 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin PF08613.11 KUM64860.1 - 2.9e-07 31.0 0.0 7.2e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Cyclin MFAP1 PF06991.11 KUM64860.1 - 0.013 15.4 1.6 0.019 14.8 1.6 1.2 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing VIT PF08487.10 KUM64861.1 - 8e-30 103.3 0.4 4.1e-29 101.0 0.2 2.2 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KUM64861.1 - 9.9e-28 97.0 0.0 2e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KUM64861.1 - 2.9e-15 55.9 0.0 1e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 KUM64861.1 - 4.6e-07 30.4 0.0 2e-06 28.4 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KUM64861.1 - 6.6e-07 29.8 0.0 1.4e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KUM64861.1 - 0.0029 17.0 0.0 0.0074 15.7 0.0 1.5 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein Auxin_repressed PF05564.12 KUM64861.1 - 2.8 8.7 4.7 1.9 9.2 1.6 2.4 2 1 1 3 3 3 0 Dormancy/auxin associated protein ERG2_Sigma1R PF04622.12 KUM64862.1 - 9.9e-98 325.6 0.2 1.2e-97 325.4 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein DUF3687 PF12459.8 KUM64862.1 - 0.018 14.5 0.2 0.046 13.2 0.2 1.6 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein UCR_6-4kD PF08997.10 KUM64862.1 - 0.12 12.4 0.3 18 5.4 0.0 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein BTB PF00651.31 KUM64865.1 - 4.8e-10 39.6 0.0 8.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain T6SS_VasJ PF16989.5 KUM64865.1 - 0.019 14.4 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ DUF3584 PF12128.8 KUM64865.1 - 0.2 9.2 1.6 0.26 8.8 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sec3_C PF09763.9 KUM64867.1 - 1.2e-226 754.4 0.0 1.7e-226 753.9 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KUM64867.1 - 1.9e-29 101.6 0.0 4e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 KUM64867.1 - 0.0069 16.7 0.1 0.019 15.3 0.1 1.8 1 0 0 1 1 1 1 Sec3 exocyst complex subunit ACP_PD PF04336.12 KUM64867.1 - 0.078 13.4 0.1 8.8 6.8 0.0 3.4 3 1 0 3 3 3 0 Acyl carrier protein phosphodiesterase DOCK_N PF16172.5 KUM64868.1 - 2.4e-115 385.5 0.0 5.8e-115 384.2 0.0 1.7 2 0 0 2 2 2 1 DOCK N-terminus DHR-2 PF06920.13 KUM64868.1 - 3.4e-40 138.2 0.7 2e-39 135.7 0.7 2.0 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KUM64868.1 - 7e-38 130.4 0.0 1.4e-37 129.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.6 KUM64868.1 - 1.1e-05 25.2 0.0 9.2e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KUM64868.1 - 2e-05 24.1 0.0 4.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KUM64868.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain PI3K_C2 PF00792.24 KUM64868.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 Na_Ca_ex PF01699.24 KUM64869.1 - 4.7e-43 146.7 34.4 3.3e-22 79.1 16.7 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein FUSC PF04632.12 KUM64870.1 - 1.9 6.9 6.3 14 4.1 0.1 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family MFS_1 PF07690.16 KUM64872.1 - 7.9e-34 117.1 24.8 7.9e-34 117.1 24.8 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Gemini_mov PF01708.16 KUM64872.1 - 1.2 9.0 3.1 3.6 7.4 0.1 2.7 2 0 0 2 2 2 0 Geminivirus putative movement protein adh_short PF00106.25 KUM64874.1 - 6.1e-27 94.4 0.0 3.8e-26 91.8 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM64874.1 - 2.5e-20 73.0 0.0 1.4e-19 70.6 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM64874.1 - 7.6e-08 32.5 0.0 1.6e-07 31.4 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KUM64874.1 - 0.00012 21.6 0.1 0.00018 21.1 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KUM64874.1 - 0.0016 18.3 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KUM64874.1 - 0.003 17.6 0.0 0.0048 17.0 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 KUM64874.1 - 0.025 13.6 0.1 0.038 13.0 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DICT PF10069.9 KUM64874.1 - 0.068 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system GDP_Man_Dehyd PF16363.5 KUM64874.1 - 0.14 11.5 0.1 0.19 11.1 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KUM64874.1 - 0.17 12.2 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Desulfoferrod_N PF06397.12 KUM64875.1 - 0.2 11.3 0.3 0.89 9.2 0.0 2.2 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain HSP70 PF00012.20 KUM64876.1 - 2.3e-05 22.8 0.0 3e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KUM64876.1 - 0.0042 15.9 0.0 0.0061 15.4 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein ApbA PF02558.16 KUM64877.1 - 3.7e-28 98.1 0.0 5.2e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KUM64877.1 - 1.9e-25 89.4 0.0 2.9e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal PglD_N PF17836.1 KUM64877.1 - 0.012 16.2 0.0 0.025 15.2 0.0 1.5 1 0 0 1 1 1 0 PglD N-terminal domain ThiF PF00899.21 KUM64877.1 - 0.059 12.7 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 ThiF family Amidohydro_2 PF04909.14 KUM64878.1 - 1.3e-32 113.7 0.0 1.6e-32 113.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KUM64878.1 - 0.023 14.1 0.0 0.066 12.6 0.0 1.7 2 0 0 2 2 2 0 TatD related DNase eIF-5a PF01287.20 KUM64879.1 - 6.6e-27 93.4 2.2 9.3e-27 92.9 2.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KUM64879.1 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain p12I PF12233.8 KUM64879.1 - 0.03 14.8 1.4 0.049 14.1 1.4 1.2 1 0 0 1 1 1 0 Human adult T cell leukemia/lymphoma virus protein Nitro_FeMo-Co PF02579.17 KUM64879.1 - 0.12 12.7 0.1 0.24 11.7 0.0 1.6 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Vps52 PF04129.12 KUM64880.1 - 3e-118 395.8 0.1 3.7e-118 395.5 0.1 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KUM64880.1 - 2e-08 33.1 0.2 2.8e-08 32.6 0.2 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 THOC7 PF05615.13 KUM64880.1 - 0.039 14.3 0.6 0.11 12.8 0.2 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 Exo70 PF03081.15 KUM64880.1 - 0.046 12.8 1.8 0.28 10.2 0.1 2.5 3 0 0 3 3 3 0 Exo70 exocyst complex subunit Sec8_exocyst PF04048.14 KUM64880.1 - 0.26 11.2 3.6 0.18 11.7 0.4 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Choline_kinase PF01633.20 KUM64881.1 - 3.2e-22 79.2 0.0 4.7e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KUM64881.1 - 0.037 14.0 0.1 0.094 12.6 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family UPF0223 PF05256.12 KUM64881.1 - 0.1 12.9 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0223) ADH_N PF08240.12 KUM64882.1 - 1.3e-34 118.4 2.7 2.4e-34 117.5 2.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM64882.1 - 1.2e-16 60.9 0.0 2.4e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KUM64882.1 - 4e-16 59.2 0.1 7.1e-16 58.3 0.0 1.4 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KUM64882.1 - 1.1e-06 29.7 0.0 2e-06 28.9 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KUM64882.1 - 0.00054 19.3 0.4 0.00078 18.8 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KUM64882.1 - 0.0015 18.9 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KUM64882.1 - 0.032 13.5 0.2 0.11 11.8 0.2 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM64882.1 - 0.035 14.3 0.1 0.085 13.1 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KUM64882.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.6 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_3 PF03447.16 KUM64882.1 - 0.057 14.1 0.0 0.14 12.8 0.0 1.7 2 0 0 2 2 1 0 Homoserine dehydrogenase, NAD binding domain DUF2318 PF10080.9 KUM64882.1 - 0.067 13.3 1.5 9.4 6.4 0.3 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) Thi4 PF01946.17 KUM64882.1 - 0.078 12.2 0.1 0.16 11.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.20 KUM64882.1 - 0.092 12.8 0.0 0.31 11.1 0.0 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KUM64882.1 - 0.11 11.5 0.5 0.15 11.1 0.5 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein XdhC_C PF13478.6 KUM64882.1 - 0.16 12.5 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain FRG1 PF06229.12 KUM64883.1 - 2.7e-52 177.3 0.1 3.8e-52 176.8 0.1 1.2 1 0 0 1 1 1 1 FRG1-like domain Arc_PepC PF06819.11 KUM64883.1 - 0.048 13.8 0.2 0.081 13.1 0.2 1.4 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain Fascin PF06268.13 KUM64883.1 - 0.049 13.9 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Fascin domain Frataxin_Cyay PF01491.16 KUM64883.1 - 0.052 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Frataxin-like domain tRNA-synt_2_TM PF16995.5 KUM64883.1 - 0.066 12.9 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 Transmembrane region of lysyl-tRNA synthetase Ham1p_like PF01725.16 KUM64884.1 - 6.2e-53 179.5 0.0 7.4e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family SRP40_C PF05022.12 KUM64885.1 - 2.6e-16 60.2 0.1 9e-16 58.5 0.1 2.0 1 0 0 1 1 1 1 SRP40, C-terminal domain P5CR_dimer PF14748.6 KUM64886.1 - 5.8e-21 74.7 0.2 3.3e-20 72.3 0.2 2.1 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KUM64886.1 - 1.2e-12 48.2 1.4 1.7e-11 44.5 1.1 2.5 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KUM64886.1 - 0.006 16.8 0.0 0.017 15.3 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KUM64886.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 KUM64887.1 - 1.4e-13 50.4 0.0 1e-11 44.3 0.0 3.3 2 1 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KUM64887.1 - 1.3e-07 31.7 0.0 5.1e-06 26.6 0.0 2.5 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KUM64887.1 - 0.024 14.9 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF3530 PF12048.8 KUM64887.1 - 0.025 14.0 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) CD20 PF04103.15 KUM64888.1 - 2.8 8.0 8.7 0.58 10.2 3.1 2.1 2 0 0 2 2 2 0 CD20-like family Herpes_gE PF02480.16 KUM64889.1 - 0.12 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CcmD PF04995.14 KUM64889.1 - 0.21 11.7 3.9 0.69 10.0 2.4 2.3 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF1992 PF09350.10 KUM64891.1 - 1.1e-17 63.9 0.2 4e-17 62.1 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) Antimicrobial11 PF08106.11 KUM64891.1 - 0.51 10.4 11.0 0.083 12.9 6.9 1.8 2 0 0 2 2 2 0 Formaecin family F-box-like PF12937.7 KUM64892.1 - 8.2e-06 25.6 0.1 3e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KUM64892.1 - 0.00096 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KUM64892.1 - 0.022 14.6 0.5 0.059 13.2 0.0 1.9 3 0 0 3 3 3 0 F-box nlz1 PF12402.8 KUM64892.1 - 0.1 13.1 0.0 0.32 11.5 0.0 1.8 1 0 0 1 1 1 0 NocA-like zinc-finger protein 1 p450 PF00067.22 KUM64893.1 - 5e-44 150.8 0.0 8.7e-44 150.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 RTA1 PF04479.13 KUM64894.1 - 1.5e-18 67.1 8.4 1.8e-18 66.9 8.4 1.0 1 0 0 1 1 1 1 RTA1 like protein F-box-like PF12937.7 KUM64895.1 - 0.0078 16.1 0.9 0.1 12.5 0.0 2.5 2 0 0 2 2 2 1 F-box-like Transferase PF02458.15 KUM64896.1 - 0.0017 17.1 0.0 0.014 14.1 0.0 2.0 1 1 0 1 1 1 1 Transferase family Nfu_N PF08712.11 KUM64897.1 - 8.4e-31 105.9 0.0 1.9e-29 101.6 0.0 2.3 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KUM64897.1 - 8.7e-28 96.3 0.3 1.8e-27 95.3 0.3 1.5 1 0 0 1 1 1 1 NifU-like domain PSP1 PF04468.12 KUM64898.1 - 7.9e-28 96.6 2.7 1.3e-27 95.9 2.7 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region RasGEF PF00617.19 KUM64899.1 - 2.6e-43 148.3 0.7 4.5e-43 147.5 0.7 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KUM64899.1 - 8.7e-15 54.9 0.0 2.4e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif MMR_HSR1 PF01926.23 KUM64899.1 - 0.035 14.2 0.1 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMAP PF15477.6 KUM64900.1 - 0.021 15.7 0.1 2.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Small acidic protein family DEC-1_N PF04625.13 KUM64900.1 - 0.11 11.5 3.8 0.13 11.3 3.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ATP_bind_3 PF01171.20 KUM64901.1 - 1.8e-19 70.2 0.0 2.7e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KUM64901.1 - 6.8e-18 63.9 2.8 6.8e-18 63.9 2.8 3.7 4 0 0 4 4 4 1 Zinc-ribbon RecR PF02132.15 KUM64901.1 - 0.0054 16.3 4.5 0.0054 16.3 4.5 2.5 3 0 0 3 3 3 1 RecR protein tRNA_Me_trans PF03054.16 KUM64901.1 - 0.064 12.0 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.20 KUM64901.1 - 0.41 10.8 6.4 4.9 7.4 0.9 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Complex1_LYR_2 PF13233.6 KUM64902.1 - 2.9e-22 79.2 0.4 3.4e-22 79.0 0.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like CHD5 PF04420.14 KUM64902.1 - 0.054 13.3 0.3 0.17 11.7 0.2 1.6 1 1 1 2 2 2 0 CHD5-like protein TPR_6 PF13174.6 KUM64902.1 - 0.69 10.7 3.8 17 6.3 1.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat NAD_binding_4 PF07993.12 KUM64903.1 - 2.1e-28 99.2 0.0 3.2e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KUM64903.1 - 1.8e-10 40.7 0.0 5.8e-09 35.8 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KUM64903.1 - 0.00063 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KUM64903.1 - 0.0019 17.4 0.0 0.0033 16.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KUM64903.1 - 0.0052 15.8 0.0 0.14 11.1 0.0 2.3 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KUM64903.1 - 0.0084 15.5 0.1 0.03 13.7 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KUM64903.1 - 0.1 13.0 0.0 0.33 11.4 0.0 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Cation_ATPase PF13246.6 KUM64903.1 - 0.16 12.1 0.0 0.7 10.0 0.0 2.0 2 0 0 2 2 2 0 Cation transport ATPase (P-type) Ank_2 PF12796.7 KUM64904.1 - 1.8e-22 79.7 0.4 2.3e-11 44.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KUM64904.1 - 1.1e-18 66.7 0.2 8.3e-05 22.9 0.1 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KUM64904.1 - 4.7e-16 58.9 0.7 8.3e-05 23.1 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM64904.1 - 1.4e-14 52.7 0.1 0.011 16.2 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KUM64904.1 - 1.3e-10 41.3 3.2 3.1e-05 24.2 0.2 4.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KUM64904.1 - 0.15 11.9 1.7 17 5.4 0.0 3.6 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain ADH_N PF08240.12 KUM64905.1 - 1.6e-26 92.3 2.4 1.6e-26 92.3 2.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM64905.1 - 3.5e-13 49.7 0.0 5.8e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KUM64905.1 - 0.00054 19.5 0.3 0.8 9.1 0.1 3.2 3 0 0 3 3 3 2 Glucose dehydrogenase C-terminus S1-like PF14444.6 KUM64905.1 - 0.18 11.8 0.1 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 S1-like Glyco_hydro_31 PF01055.26 KUM64906.1 - 5.3e-157 523.5 0.7 7e-157 523.1 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KUM64906.1 - 1.3e-31 109.2 0.0 2.4e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KUM64906.1 - 8.9e-16 58.0 0.7 3.2e-15 56.2 0.7 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like Rotavirus_VP7 PF05868.11 KUM64906.1 - 0.17 11.3 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 tRNA-synt_2b PF00587.25 KUM64907.1 - 1e-31 110.3 0.0 1.6e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KUM64907.1 - 2.1e-07 31.0 0.1 8.6e-07 29.0 0.1 2.0 1 1 0 1 1 1 1 Anticodon binding domain HMGL-like PF00682.19 KUM64908.1 - 9.1e-80 268.0 0.0 1.3e-79 267.5 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KUM64908.1 - 2e-23 82.8 0.0 4.5e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF3900 PF13039.6 KUM64908.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3900) Glyco_hydro_16 PF00722.21 KUM64909.1 - 2.2e-43 147.8 2.5 2.2e-43 147.8 2.5 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 YjcZ PF13990.6 KUM64910.1 - 0.0031 16.9 0.0 0.0086 15.5 0.0 1.8 1 1 0 1 1 1 1 YjcZ-like protein Med3 PF11593.8 KUM64910.1 - 0.0046 16.2 0.1 0.0046 16.2 0.1 1.8 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal Baculo_PEP_C PF04513.12 KUM64910.1 - 0.2 11.7 1.6 9.2 6.3 0.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 KUM64910.1 - 4.5 6.7 5.4 9.2 5.6 1.4 2.7 2 1 0 2 2 2 0 Golgin subfamily A member 5 Ribosomal_S7 PF00177.21 KUM64911.1 - 3.7e-36 124.0 1.1 4.7e-36 123.7 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SDA1 PF05285.12 KUM64912.1 - 1.3e-91 307.7 45.7 1.3e-91 307.7 45.7 2.8 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 KUM64912.1 - 4e-21 75.1 0.5 1.1e-20 73.7 0.2 2.0 2 0 0 2 2 2 1 NUC130/3NT domain Sulfatase PF00884.23 KUM64913.1 - 1.7e-63 214.9 0.5 2.4e-63 214.4 0.5 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KUM64913.1 - 0.014 15.0 2.7 0.034 13.7 2.7 1.6 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase AMP-binding PF00501.28 KUM64914.1 - 6.3e-69 232.6 0.5 1.9e-37 128.9 0.0 4.2 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 KUM64914.1 - 1.3e-09 38.8 0.0 3.7e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 KUM64914.1 - 0.019 15.0 0.3 0.044 13.8 0.3 1.5 1 0 0 1 1 1 0 Gas vesicle protein G MFS_1 PF07690.16 KUM64915.1 - 1.2e-30 106.7 22.2 1.1e-29 103.5 24.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_31 PF01055.26 KUM64916.1 - 1.3e-87 294.9 0.4 2.6e-87 293.9 0.4 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KUM64916.1 - 5.7e-13 49.0 0.0 1.7e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KUM64916.1 - 0.0022 18.2 0.0 0.0062 16.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Fungal_trans PF04082.18 KUM64918.1 - 1.4e-06 27.6 0.0 3e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KUM64920.1 - 1.1e-30 106.7 28.0 1.8e-30 106.0 28.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ADP_ribosyl_GH PF03747.14 KUM64920.1 - 1.1e-15 58.1 1.6 1.1e-14 54.9 0.2 2.3 1 1 1 2 2 2 1 ADP-ribosylglycohydrolase BT1 PF03092.16 KUM64920.1 - 0.061 11.5 2.0 0.12 10.6 2.0 1.4 1 0 0 1 1 1 0 BT1 family PTR2 PF00854.21 KUM64920.1 - 0.15 10.9 7.1 5 5.8 5.8 2.5 2 0 0 2 2 2 0 POT family Sugar_tr PF00083.24 KUM64921.1 - 3.3e-110 369.0 27.2 4.1e-110 368.7 27.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM64921.1 - 1.4e-19 70.2 39.9 2e-14 53.3 15.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KUM64921.1 - 0.0037 15.6 2.7 0.0037 15.6 2.7 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF2201_N PF13203.6 KUM64922.1 - 0.1 12.2 1.2 0.13 11.9 1.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain ZapB PF06005.12 KUM64922.1 - 0.14 12.6 8.2 0.54 10.7 6.5 2.2 2 0 0 2 2 2 0 Cell division protein ZapB TraF PF13728.6 KUM64922.1 - 0.33 10.8 5.9 0.42 10.4 5.9 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein CdvA PF18822.1 KUM64922.1 - 0.45 10.4 11.1 0.11 12.3 5.6 2.0 1 1 1 2 2 2 0 CdvA-like coiled-coil domain OmpH PF03938.14 KUM64922.1 - 1.1 9.6 9.7 1.4 9.2 9.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NYD-SP28 PF14772.6 KUM64922.1 - 1.4 9.0 14.7 3.3 7.8 14.7 1.6 1 1 0 1 1 1 0 Sperm tail TPK_catalytic PF04263.16 KUM64922.1 - 2.9 7.9 6.3 60 3.7 6.3 2.1 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DivIC PF04977.15 KUM64922.1 - 3.3 7.5 7.2 0.75 9.6 3.6 1.7 2 0 0 2 2 2 0 Septum formation initiator MFS_1 PF07690.16 KUM64924.1 - 0.00013 21.0 0.2 0.00016 20.7 0.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_S9 PF00326.21 KUM64925.1 - 1.4e-39 135.7 0.6 6.9e-38 130.3 0.6 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 KUM64925.1 - 1.1e-10 41.1 0.3 0.014 15.3 0.0 3.7 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Abhydrolase_2 PF02230.16 KUM64925.1 - 1.2e-07 31.7 0.0 0.017 15.0 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KUM64925.1 - 2.6e-06 27.3 0.4 0.056 13.1 0.6 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KUM64925.1 - 4.2e-06 26.5 0.0 0.00029 20.4 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KUM64925.1 - 8.9e-06 25.1 0.1 0.047 13.0 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KUM64925.1 - 7.3e-05 22.5 5.0 0.0028 17.3 1.3 2.5 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KUM64925.1 - 0.0001 23.0 2.9 0.00029 21.5 2.9 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KUM64925.1 - 0.00028 20.8 0.1 0.00099 19.0 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.14 KUM64925.1 - 0.0019 17.6 0.6 0.13 11.6 0.3 2.2 2 0 0 2 2 2 1 Secretory lipase DPPIV_N PF00930.21 KUM64925.1 - 0.0023 16.8 0.0 0.59 8.8 0.0 2.6 2 1 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region FSH1 PF03959.13 KUM64925.1 - 0.0035 17.0 0.0 0.01 15.5 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) AXE1 PF05448.12 KUM64925.1 - 0.045 12.4 0.0 0.078 11.6 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_4 PF08386.10 KUM64925.1 - 0.067 13.3 0.1 0.48 10.6 0.0 2.2 2 0 0 2 2 2 0 TAP-like protein DUF3748 PF12566.8 KUM64925.1 - 0.087 12.8 0.5 22 5.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3748) Phytase PF02333.15 KUM64925.1 - 0.096 11.6 0.5 5 6.0 0.0 2.2 2 0 0 2 2 2 0 Phytase Mtc PF03820.17 KUM64926.1 - 1.1e-118 395.8 0.0 1.3e-118 395.7 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Amidase PF01425.21 KUM64927.1 - 6.7e-80 269.2 1.4 3.7e-79 266.8 1.4 1.9 1 1 0 1 1 1 1 Amidase Pkinase PF00069.25 KUM64928.1 - 1.2e-49 169.1 0.0 2.3e-49 168.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM64928.1 - 6.7e-19 68.2 0.0 3.3e-18 65.9 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase TAF4 PF05236.14 KUM64929.1 - 4e-30 105.5 0.5 8.5e-23 81.5 1.3 2.2 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.8 KUM64930.1 - 1.1e-82 276.8 0.0 1.6e-82 276.3 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KUM64930.1 - 1.3e-28 99.5 0.0 2.9e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 KUM64930.1 - 1.3e-18 67.7 0.1 2.5e-18 66.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KUM64930.1 - 5.1e-16 58.7 0.0 8.3e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KUM64930.1 - 1.4e-11 44.1 0.0 3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KUM64930.1 - 0.0018 17.8 0.1 0.004 16.7 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KUM64930.1 - 0.0083 16.0 0.0 0.019 14.9 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Aminotran_3 PF00202.21 KUM64931.1 - 1.5e-90 303.8 0.0 2.1e-90 303.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III EGF_alliinase PF04863.13 KUM64931.1 - 0.071 13.5 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 Alliinase EGF-like domain TrkH PF02386.16 KUM64932.1 - 2.2e-18 66.0 5.3 2.9e-12 45.8 0.1 2.1 2 0 0 2 2 2 2 Cation transport protein DAO PF01266.24 KUM64933.1 - 5.1e-35 121.7 0.0 5.9e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.21 KUM64933.1 - 1.4e-06 27.9 0.0 2.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 ThiF family FAD_binding_2 PF00890.24 KUM64933.1 - 5e-06 25.8 0.1 0.035 13.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KUM64933.1 - 8.7e-05 21.9 0.0 0.031 13.5 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM64933.1 - 9.5e-05 22.6 0.0 0.00031 20.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KUM64933.1 - 0.00061 19.0 0.0 0.054 12.6 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KUM64933.1 - 0.0026 18.3 0.0 0.014 16.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KUM64933.1 - 0.0042 17.2 0.0 0.0073 16.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KUM64933.1 - 0.033 13.4 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KUM64933.1 - 0.083 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 KUM64933.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 KUM64933.1 - 0.22 11.5 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Noc2 PF03715.13 KUM64934.1 - 4.5e-127 423.4 0.1 4.5e-127 423.4 0.1 2.0 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 KUM64934.1 - 0.0024 16.2 0.0 0.0024 16.2 0.0 3.1 3 0 0 3 3 3 1 Nop14-like family TrkH PF02386.16 KUM64935.1 - 4.4e-71 239.8 0.1 5.4e-71 239.5 0.1 1.0 1 0 0 1 1 1 1 Cation transport protein Methyltransf_16 PF10294.9 KUM64936.1 - 7.4e-20 71.4 0.0 1.6e-19 70.3 0.0 1.5 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KUM64936.1 - 0.0012 18.7 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM64936.1 - 0.0037 17.9 0.0 0.0076 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM64936.1 - 0.059 13.2 0.0 0.19 11.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain VPS28 PF03997.12 KUM64937.1 - 4.7e-73 244.9 0.0 6.7e-73 244.4 0.0 1.2 1 0 0 1 1 1 1 VPS28 protein DEAD PF00270.29 KUM64938.1 - 1.4e-27 96.6 0.0 7.3e-27 94.3 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM64938.1 - 3.8e-23 81.9 0.0 1.2e-22 80.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM64938.1 - 1.6e-05 24.9 0.1 4.4e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 KUM64938.1 - 0.027 13.3 0.0 0.055 12.3 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer LEA_4 PF02987.16 KUM64940.1 - 0.049 13.7 0.2 0.073 13.2 0.2 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein NUDE_C PF04880.13 KUM64940.1 - 0.058 13.9 1.1 0.062 13.8 1.1 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region ATP-synt_G PF04718.15 KUM64941.1 - 1.1e-22 80.7 0.0 1.2e-22 80.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Zn_clus PF00172.18 KUM64942.1 - 4e-11 42.9 10.0 6e-11 42.3 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med9 PF07544.13 KUM64942.1 - 0.011 15.8 0.1 0.016 15.3 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Cep57_CLD PF14073.6 KUM64942.1 - 0.014 15.4 4.3 0.02 14.9 0.4 2.0 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Syntaphilin PF15290.6 KUM64942.1 - 0.029 14.0 0.5 0.042 13.5 0.5 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Tropomyosin PF00261.20 KUM64942.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Tropomyosin Spc24 PF08286.11 KUM64942.1 - 0.12 12.6 0.2 0.18 12.0 0.2 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 CCDC106 PF15794.5 KUM64942.1 - 0.14 11.8 2.2 0.16 11.6 1.7 1.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 TssO PF17561.2 KUM64942.1 - 0.21 11.7 0.0 0.27 11.4 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO NYD-SP28_assoc PF14775.6 KUM64942.1 - 0.61 10.2 2.6 1.7 8.8 2.6 1.8 1 1 0 1 1 1 0 Sperm tail C-terminal domain EMP24_GP25L PF01105.24 KUM64942.1 - 1.9 8.4 3.8 4.1 7.3 1.4 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Caps_synth PF05704.12 KUM64943.1 - 0.18 11.2 0.2 0.23 10.8 0.2 1.0 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein GST_N PF02798.20 KUM64946.1 - 1.1e-13 51.3 0.0 4.5e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KUM64946.1 - 2e-13 50.3 0.0 3.5e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KUM64946.1 - 2.4e-13 50.3 0.0 5.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KUM64946.1 - 2.1e-12 47.1 0.0 4.9e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KUM64946.1 - 4.2e-09 36.5 0.0 7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KUM64946.1 - 0.001 19.0 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3791 PF12668.7 KUM64946.1 - 0.088 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) RNR_inhib PF08591.10 KUM64947.1 - 1.3e-17 65.1 0.1 2.5e-17 64.1 0.1 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor DUF2293 PF10056.9 KUM64949.1 - 1.7e-29 101.9 0.2 7e-29 99.9 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) RE_BstXI PF09552.10 KUM64949.1 - 0.0024 17.1 0.1 0.31 10.2 0.0 2.1 2 0 0 2 2 2 2 BstXI restriction endonuclease Gly_transf_sug PF04488.15 KUM64951.1 - 3.2e-12 46.9 0.6 2.2e-11 44.2 0.6 2.2 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif K_oxygenase PF13434.6 KUM64953.1 - 4.6e-11 42.5 0.0 7e-09 35.3 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KUM64953.1 - 8.4e-09 35.1 0.0 9.8e-06 25.0 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM64953.1 - 1.4e-05 24.5 0.5 0.008 15.5 0.2 3.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KUM64953.1 - 4.1e-05 22.2 0.0 0.00021 19.8 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 KUM64953.1 - 8.8e-05 22.5 0.2 0.68 9.9 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KUM64953.1 - 0.0004 20.4 0.0 0.0041 17.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KUM64953.1 - 0.0032 17.9 0.0 0.12 12.8 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding DUF498 PF04430.14 KUM64953.1 - 0.0036 17.3 0.0 1.4 9.0 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF498/DUF598) NAD_binding_8 PF13450.6 KUM64953.1 - 0.013 15.7 0.1 0.046 14.0 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 KUM64953.1 - 0.074 12.4 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 ThiF family DnaJ PF00226.31 KUM64956.1 - 2.7e-18 65.8 0.6 2.7e-18 65.8 0.6 1.9 2 0 0 2 2 2 1 DnaJ domain MBOAT PF03062.19 KUM64957.1 - 3.3e-37 128.7 23.9 1.4e-36 126.6 23.9 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ribosomal_L13 PF00572.18 KUM64958.1 - 8.8e-12 45.4 0.0 7.8e-10 39.1 0.0 2.5 1 1 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.20 KUM64958.1 - 0.029 14.1 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Metallophos PF00149.28 KUM64959.1 - 2.7e-10 41.1 0.5 4.2e-10 40.5 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AMP-binding PF00501.28 KUM64960.1 - 5.1e-51 173.6 0.2 6.2e-51 173.3 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM64960.1 - 1e-18 68.1 0.0 3.5e-18 66.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KUM64961.1 - 1.4e-08 33.7 0.0 1.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ifi-6-16 PF06140.13 KUM64961.1 - 0.022 14.7 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Interferon-induced 6-16 family Peptidase_M28 PF04389.17 KUM64962.1 - 4.4e-34 117.9 0.0 7e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KUM64962.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 LRR_6 PF13516.6 KUM64963.1 - 4.9e-13 48.0 20.9 1.3 9.3 0.0 11.5 12 0 0 12 12 12 5 Leucine Rich repeat F-box-like PF12937.7 KUM64963.1 - 2.1e-11 43.6 0.1 1e-10 41.3 0.0 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KUM64963.1 - 1.9e-08 34.5 14.8 1.7 9.1 0.0 7.9 3 2 3 8 8 8 5 Leucine Rich repeats (2 copies) F-box PF00646.33 KUM64963.1 - 4.3e-05 23.3 0.0 0.00021 21.1 0.0 2.3 1 0 0 1 1 1 1 F-box domain DUF1699 PF08004.11 KUM64963.1 - 0.00074 19.2 1.0 0.088 12.5 0.0 3.5 3 2 1 4 4 4 1 Protein of unknown function (DUF1699) Recep_L_domain PF01030.24 KUM64963.1 - 0.081 13.0 0.1 29 4.8 0.0 3.7 2 2 1 4 4 4 0 Receptor L domain Epimerase PF01370.21 KUM64964.1 - 6.3e-23 81.5 0.5 4.3e-22 78.7 0.5 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM64964.1 - 1.6e-14 54.0 0.0 3.9e-14 52.8 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KUM64964.1 - 3.2e-09 36.2 0.0 8.7e-09 34.8 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KUM64964.1 - 1.2e-08 34.4 0.0 9e-07 28.3 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KUM64964.1 - 1.9e-07 31.1 0.0 4e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KUM64964.1 - 2.2e-06 27.0 0.0 4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KUM64964.1 - 0.0043 16.2 0.0 0.02 14.1 0.0 2.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KUM64964.1 - 0.05 13.1 0.1 0.11 12.0 0.1 1.5 2 0 0 2 2 2 0 NmrA-like family KR PF08659.10 KUM64964.1 - 0.14 12.1 0.2 0.77 9.6 0.2 2.1 1 1 0 1 1 1 0 KR domain Pkinase PF00069.25 KUM64967.1 - 5.1e-64 216.2 0.0 6.1e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM64967.1 - 6.8e-36 123.9 0.0 9.2e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM64967.1 - 1.3e-07 31.2 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KUM64967.1 - 2.5e-05 23.2 0.0 3.8e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KUM64967.1 - 0.021 14.4 0.0 0.84 9.2 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KUM64967.1 - 0.09 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec39 PF08314.11 KUM64968.1 - 5.3e-275 914.6 2.6 6e-275 914.4 2.6 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 F-box-like PF12937.7 KUM64970.1 - 2e-05 24.4 0.0 5.3e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KUM64970.1 - 0.01 15.7 0.8 0.075 12.9 0.1 2.5 2 0 0 2 2 2 0 F-box domain F-box_5 PF18511.1 KUM64970.1 - 0.012 15.2 0.7 0.13 11.8 0.2 2.5 2 0 0 2 2 2 0 F-box LRR_4 PF12799.7 KUM64970.1 - 0.042 14.3 0.4 83 3.8 0.0 4.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KUM64970.1 - 0.17 12.1 1.3 41 4.6 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeat Ribosomal_S26e PF01283.19 KUM64971.1 - 1.8e-52 176.3 7.6 2.7e-52 175.7 7.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KUM64971.1 - 0.054 13.5 3.0 0.12 12.4 0.0 2.6 3 0 0 3 3 3 0 Zinc binding domain Fer4_7 PF12838.7 KUM64971.1 - 0.054 14.1 3.0 0.86 10.2 1.9 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain CBS PF00571.28 KUM64972.1 - 5.1e-35 119.7 5.0 5e-09 36.5 0.0 5.3 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 KUM64972.1 - 2.1e-10 40.4 0.0 6.9e-10 38.7 0.0 1.9 1 1 0 1 1 1 1 PB1 domain Importin_rep_4 PF18808.1 KUM64973.1 - 8.5e-34 115.7 6.2 4.3e-33 113.5 1.5 3.6 3 0 0 3 3 3 1 Importin repeat Importin_rep_5 PF18816.1 KUM64973.1 - 3.9e-22 78.3 1.7 3.9e-22 78.3 1.7 2.2 2 0 0 2 2 1 1 Importin repeat HEAT_EZ PF13513.6 KUM64973.1 - 1.5e-20 73.2 14.2 3.5e-10 40.1 0.8 9.0 7 1 1 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.6 KUM64973.1 - 5.9e-16 58.6 8.4 7.6e-05 23.0 0.0 7.7 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.22 KUM64973.1 - 2.5e-14 52.1 15.1 0.01 16.0 0.0 12.0 15 0 0 15 15 14 2 HEAT repeat Importin_rep_6 PF18829.1 KUM64973.1 - 1.1e-13 51.3 0.7 1.1e-13 51.3 0.7 3.1 3 0 0 3 3 3 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 KUM64973.1 - 1.8e-09 38.0 0.7 0.0056 17.2 0.0 5.9 2 2 4 6 6 5 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KUM64973.1 - 7.5e-09 35.7 0.7 0.21 11.5 0.0 6.6 5 4 1 7 7 6 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KUM64973.1 - 1.7e-08 34.7 0.2 0.17 12.0 0.0 5.1 4 2 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 KUM64973.1 - 1.8e-08 34.0 7.6 4.9e-06 25.9 0.8 5.3 5 1 1 6 6 6 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KUM64973.1 - 1.5e-07 31.2 2.1 0.25 10.9 0.0 6.5 6 3 2 8 8 7 2 CLASP N terminal Adaptin_N PF01602.20 KUM64973.1 - 3e-06 26.1 0.3 0.0052 15.4 0.2 3.2 1 1 1 2 2 2 2 Adaptin N terminal region RIX1 PF08167.12 KUM64973.1 - 3.8e-06 26.8 0.1 0.013 15.3 0.1 4.4 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis IFRD PF05004.13 KUM64973.1 - 8.4e-06 25.1 2.3 0.066 12.3 0.1 4.1 2 2 1 3 3 3 2 Interferon-related developmental regulator (IFRD) MMS19_N PF14500.6 KUM64973.1 - 0.00028 20.5 0.8 1.1 8.8 0.1 4.3 6 0 0 6 6 6 2 Dos2-interacting transcription regulator of RNA-Pol-II Arm PF00514.23 KUM64973.1 - 0.00045 20.2 5.0 0.16 12.1 0.1 4.0 4 0 0 4 4 3 2 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 KUM64973.1 - 0.013 14.8 0.8 13 4.8 0.0 4.4 4 1 1 5 5 5 0 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 KUM64973.1 - 0.029 14.5 0.4 22 5.3 0.2 5.2 6 1 1 7 7 5 0 Required for nuclear transport of RNA pol II C-terminus 1 DNA_alkylation PF08713.11 KUM64973.1 - 0.036 13.8 0.1 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 DNA alkylation repair enzyme IBN_N PF03810.19 KUM64973.1 - 0.046 13.6 0.1 0.69 9.9 0.0 2.9 2 0 0 2 2 2 0 Importin-beta N-terminal domain MIF4G_like_2 PF09090.11 KUM64973.1 - 0.14 11.6 1.3 0.56 9.6 0.2 2.3 2 0 0 2 2 2 0 MIF4G like GP24_25 PF17388.2 KUM64973.1 - 0.24 11.4 2.6 0.6 10.1 0.4 2.9 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 V-ATPase_H_N PF03224.14 KUM64973.1 - 0.52 9.6 3.4 8.4 5.6 0.1 3.4 3 1 0 3 3 3 0 V-ATPase subunit H Telomere_reg-2 PF10193.9 KUM64973.1 - 1.3 9.4 7.2 2.4 8.6 0.4 4.2 3 2 1 4 4 3 0 Telomere length regulation protein Fe-ADH PF00465.19 KUM64975.1 - 2.1e-68 230.8 0.0 2.7e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KUM64975.1 - 8.6e-10 38.7 0.1 0.0011 18.7 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Glyco_hydro_28 PF00295.17 KUM64976.1 - 5.3e-45 153.9 7.0 3.1e-44 151.4 7.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_49 PF03718.13 KUM64976.1 - 0.32 11.0 8.4 6.5 6.8 0.0 4.0 4 1 0 4 4 4 0 Glycosyl hydrolase family 49 Bac_rhamnosid6H PF17389.2 KUM64977.1 - 6.7e-16 58.5 3.0 2.1e-13 50.3 2.4 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KUM64977.1 - 4.5e-06 26.4 0.0 1.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 KUM64977.1 - 0.0017 17.3 0.1 0.0025 16.7 0.1 1.1 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid PF05592.11 KUM64977.1 - 0.094 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Chalcone_2 PF16035.5 KUM64978.1 - 2.9e-81 272.1 0.0 4.3e-81 271.6 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 KUM64978.1 - 0.00044 20.4 0.1 0.0027 17.8 0.0 2.1 2 0 0 2 2 2 1 Chalcone isomerase-like Pro_racemase PF05544.11 KUM64979.1 - 4.1e-128 427.0 0.1 4.6e-128 426.8 0.1 1.0 1 0 0 1 1 1 1 Proline racemase CorA PF01544.18 KUM64980.1 - 9.1e-06 25.2 0.7 1.7e-05 24.3 0.7 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Lipase_GDSL_2 PF13472.6 KUM64981.1 - 8.8e-20 71.8 0.0 1.1e-19 71.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.6 KUM64981.1 - 6e-05 23.3 0.0 0.017 15.3 0.0 2.5 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KUM64981.1 - 0.00019 21.5 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AA_permease_2 PF13520.6 KUM64984.1 - 8.8e-50 169.8 51.2 1.1e-49 169.5 51.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM64984.1 - 5.4e-29 101.1 46.9 6.8e-29 100.8 46.9 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 KUM64985.1 - 1.6e-25 89.7 3.5 2.7e-25 89.0 3.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM64985.1 - 0.015 15.4 6.4 0.015 15.4 6.4 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3535 PF12054.8 KUM64986.1 - 1.7e-126 423.0 0.0 8.4e-126 420.7 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KUM64986.1 - 8.4e-60 202.3 0.0 1.9e-59 201.2 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KUM64986.1 - 6.7e-19 68.3 0.0 1.8e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KUM64986.1 - 3.8e-16 57.8 10.3 0.13 12.5 0.0 9.5 9 0 0 9 9 8 5 HEAT repeat Vac14_Fab1_bd PF12755.7 KUM64986.1 - 5.9e-07 30.0 0.0 0.066 13.8 0.0 4.1 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 KUM64986.1 - 1.1e-06 28.9 7.9 0.022 15.2 0.2 6.5 5 1 1 6 6 6 1 HEAT repeats Cnd1 PF12717.7 KUM64986.1 - 0.00012 22.1 0.0 0.1 12.7 0.0 4.3 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 KUM64986.1 - 0.00063 20.0 0.0 2.1 8.7 0.0 4.8 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain TIP120 PF08623.10 KUM64986.1 - 0.0046 16.7 0.2 2.7 7.7 0.0 3.4 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) CLASP_N PF12348.8 KUM64986.1 - 0.011 15.3 0.6 4.4 6.8 0.0 3.9 4 1 2 6 6 6 0 CLASP N terminal HEAT_EZ PF13513.6 KUM64986.1 - 1.7 9.3 17.0 37 5.0 0.0 7.0 8 0 0 8 8 7 0 HEAT-like repeat Metal_resist PF13801.6 KUM64986.1 - 4.5 7.5 8.1 1.6 9.0 0.3 3.0 3 0 0 3 3 3 0 Heavy-metal resistance Ndufs5 PF10200.9 KUM64987.1 - 0.00046 20.4 0.0 0.00065 19.9 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX6B PF02297.17 KUM64987.1 - 0.012 15.8 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb CHCH PF06747.13 KUM64987.1 - 0.016 15.3 0.2 0.031 14.4 0.1 1.6 2 0 0 2 2 2 0 CHCH domain DUF3128 PF11326.8 KUM64987.1 - 0.025 15.0 1.0 0.16 12.4 1.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) LysM PF01476.20 KUM64988.1 - 7.6e-05 22.7 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 LysM domain adh_short PF00106.25 KUM64989.1 - 1.3e-13 50.9 0.0 2.2e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM64989.1 - 1.3e-09 38.0 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM64989.1 - 3.3e-08 33.6 0.0 4.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Sulfotransfer_4 PF17784.1 KUM64989.1 - 0.093 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain Fungal_trans_2 PF11951.8 KUM64990.1 - 0.0012 17.7 4.0 0.0012 17.7 4.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Med15_fungi PF05397.12 KUM64991.1 - 9.6e-34 116.0 0.3 9.6e-34 116.0 0.3 5.1 5 0 0 5 5 5 1 Mediator complex subunit 15 KIX_2 PF16987.5 KUM64991.1 - 2e-09 37.3 0.6 2e-09 37.3 0.6 3.7 4 0 0 4 4 4 1 KIX domain LMBR1 PF04791.16 KUM64992.1 - 2.3e-130 435.9 1.0 2.7e-130 435.7 1.0 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Apolipoprotein PF01442.18 KUM64992.1 - 1.4 8.8 3.6 1 9.2 0.3 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain BAG PF02179.16 KUM64993.1 - 4.9e-15 55.7 0.0 8.1e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KUM64993.1 - 0.00056 19.6 0.0 0.00095 18.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YopE_N PF09020.10 KUM64993.1 - 0.97 9.7 6.1 10 6.4 0.5 2.3 2 0 0 2 2 2 0 YopE, N terminal Glutaredoxin PF00462.24 KUM64995.1 - 5.8e-21 74.5 0.0 9.8e-21 73.7 0.0 1.4 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_2 PF13098.6 KUM64995.1 - 0.0021 18.5 0.1 0.0036 17.7 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 KUM64995.1 - 0.0031 17.9 0.1 0.0042 17.5 0.1 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Toprim_2 PF13155.6 KUM64995.1 - 0.046 14.1 0.1 0.052 14.0 0.1 1.2 1 0 0 1 1 1 0 Toprim-like Thioredoxin PF00085.20 KUM64995.1 - 0.051 13.6 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.6 KUM64995.1 - 0.053 13.7 0.6 4.3 7.5 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin DSBA PF01323.20 KUM64995.1 - 0.069 12.9 0.1 1.1 9.1 0.1 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain TraF PF13728.6 KUM64995.1 - 0.072 12.9 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Adaptin_N PF01602.20 KUM64996.1 - 9.5e-141 469.9 1.0 1.1e-140 469.7 1.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KUM64996.1 - 1.4e-17 64.0 0.0 2.6e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KUM64996.1 - 6.7e-08 32.7 6.9 0.0004 20.5 0.1 4.3 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KUM64996.1 - 4.6e-07 30.1 0.8 0.065 13.6 0.0 4.1 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KUM64996.1 - 0.0018 18.4 0.9 6.7 7.3 0.1 4.4 3 0 0 3 3 3 1 HEAT repeat DUF3730 PF12530.8 KUM64996.1 - 0.0051 16.4 0.0 0.49 9.9 0.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3730) RICTOR_M PF14666.6 KUM64996.1 - 0.094 12.5 0.5 0.38 10.5 0.0 2.3 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain Arm PF00514.23 KUM64996.1 - 0.19 11.8 1.6 1.3e+02 2.8 0.1 5.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat EamA PF00892.20 KUM64997.1 - 5.7e-13 49.2 21.2 1.2e-06 28.7 1.8 2.4 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KUM64997.1 - 8.8e-10 38.2 0.4 1.5e-09 37.4 0.4 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KUM64997.1 - 6.8e-05 22.2 7.9 0.00018 20.8 7.9 1.6 1 1 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 KUM64997.1 - 0.00048 19.2 4.8 0.00084 18.4 0.1 2.5 2 1 0 3 3 3 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 KUM64997.1 - 0.00058 19.3 4.2 0.00087 18.7 0.1 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family CPP1-like PF11833.8 KUM64997.1 - 0.06 13.0 0.1 0.06 13.0 0.1 2.0 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Ribonuc_L-PSP PF01042.21 KUM64998.1 - 1.2e-30 106.0 0.0 8.8e-22 77.4 0.0 2.0 1 1 1 2 2 2 2 Endoribonuclease L-PSP PALP PF00291.25 KUM64999.1 - 2.9e-37 128.7 0.0 3.4e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 60KD_IMP PF02096.20 KUM65000.1 - 3.9e-10 39.9 0.1 4.8e-10 39.6 0.1 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein PP2C PF00481.21 KUM65001.1 - 1.1e-43 149.7 0.0 2e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KUM65001.1 - 0.0016 18.1 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KUM65001.1 - 0.0017 18.3 0.0 2.2 8.1 0.0 3.1 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Ank_3 PF13606.6 KUM65002.1 - 2.6e-08 33.5 0.0 0.013 16.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KUM65002.1 - 2.4e-07 31.2 0.1 9.4e-07 29.3 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KUM65002.1 - 5.5e-06 26.6 0.1 0.012 15.9 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KUM65002.1 - 3.2e-05 24.2 0.0 0.039 14.4 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KUM65002.1 - 0.00011 22.7 0.6 0.0017 18.9 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PPR_long PF17177.4 KUM65002.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP ALG11_N PF15924.5 KUM65003.1 - 1.1e-82 277.2 0.1 1.5e-82 276.7 0.1 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KUM65003.1 - 8.5e-21 74.2 0.0 1.4e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KUM65003.1 - 9.9e-11 42.2 0.0 3.3e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KUM65003.1 - 0.00055 20.0 0.2 0.0021 18.1 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase Family 4 AAA_5 PF07728.14 KUM65003.1 - 0.025 14.6 0.0 0.057 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Glyco_trans_1_2 PF13524.6 KUM65003.1 - 0.026 14.9 0.1 0.054 13.9 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 TFIIS_C PF01096.18 KUM65004.1 - 5.3e-20 71.0 2.4 5.3e-20 71.0 2.4 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KUM65004.1 - 6.1e-08 32.4 6.3 3.9e-07 29.8 2.0 3.2 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit IBR PF01485.21 KUM65004.1 - 0.0028 17.8 4.5 0.68 10.2 0.3 2.4 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain zinc_ribbon_4 PF13717.6 KUM65004.1 - 0.0092 15.9 4.6 1.7 8.6 0.2 2.9 2 1 0 2 2 2 2 zinc-ribbon domain Zn_ribbon_recom PF13408.6 KUM65004.1 - 0.029 14.9 0.3 1.5 9.3 0.0 2.5 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain PriA_CRR PF18319.1 KUM65004.1 - 0.13 12.3 2.3 2.7 8.1 0.2 3.0 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain MqsA_antitoxin PF15731.5 KUM65004.1 - 0.16 12.0 0.1 0.16 12.0 0.1 1.5 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA zf-H2C2_2 PF13465.6 KUM65004.1 - 1.1 9.9 6.9 5.1 7.7 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger double domain TF_Zn_Ribbon PF08271.12 KUM65004.1 - 1.2 8.7 7.6 3.6 7.2 0.7 2.9 3 1 0 3 3 3 0 TFIIB zinc-binding DZR PF12773.7 KUM65004.1 - 1.3 9.1 7.0 0.92 9.6 0.4 2.6 2 1 0 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.6 KUM65004.1 - 2.8 7.9 6.6 15 5.6 2.2 3.0 2 1 0 2 2 2 0 Nudix N-terminal zf-TFIIB PF13453.6 KUM65004.1 - 8.9 5.7 9.3 0.55 9.6 0.5 3.0 3 1 0 3 3 3 0 Transcription factor zinc-finger zinc_ribbon_2 PF13240.6 KUM65004.1 - 9 6.2 11.3 4.1 7.2 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain MAGE PF01454.19 KUM65006.1 - 8.9e-61 205.3 0.0 1.3e-60 204.8 0.0 1.2 1 0 0 1 1 1 1 MAGE family GTP_EFTU PF00009.27 KUM65007.1 - 2.2e-54 184.0 0.0 3.3e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KUM65007.1 - 4.5e-42 142.9 0.0 1.2e-41 141.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KUM65007.1 - 1.7e-12 47.5 0.6 5e-12 46.0 0.6 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KUM65007.1 - 0.0002 21.4 0.2 0.0056 16.8 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Semialdhyde_dhC PF02774.18 KUM65007.1 - 0.018 15.1 0.1 0.26 11.3 0.1 2.2 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain FlpD PF02662.16 KUM65007.1 - 0.028 14.4 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit DNA_meth_N PF18284.1 KUM65007.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 DNA methylase N-terminal domain GTP_EFTU_D4 PF14578.6 KUM65007.1 - 0.13 12.2 2.9 0.094 12.6 0.7 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 G-alpha PF00503.20 KUM65007.1 - 0.17 11.0 0.1 0.63 9.1 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit MFS_1 PF07690.16 KUM65010.1 - 2e-24 86.2 13.7 2.4e-24 85.9 13.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM65010.1 - 7.2e-05 21.8 6.5 8.3e-05 21.6 6.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter HKR_ArcB_TM PF18415.1 KUM65010.1 - 4.8 8.1 0.0 4.8 8.1 0.0 3.3 3 1 0 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain adh_short_C2 PF13561.6 KUM65011.1 - 6.3e-51 173.2 0.0 7.9e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM65011.1 - 1.8e-45 154.8 0.2 2.1e-45 154.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM65011.1 - 1.7e-08 34.6 0.0 2.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM65011.1 - 0.01 15.3 0.1 0.024 14.1 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KUM65011.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans_2 PF11951.8 KUM65012.1 - 1.3e-14 53.9 0.0 8.1e-14 51.2 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM65012.1 - 1.3e-07 31.6 10.6 2.4e-07 30.7 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transketolase_N PF00456.21 KUM65013.1 - 1.3e-123 412.3 0.1 3e-123 411.0 0.0 1.6 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KUM65013.1 - 1.9e-37 128.6 0.2 5.2e-37 127.2 0.2 1.7 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KUM65013.1 - 5.1e-06 26.4 0.0 1.5e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 KUM65013.1 - 5.2e-06 25.6 0.1 1.2e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KUM65013.1 - 3.7e-05 23.1 0.0 0.00012 21.4 0.0 1.8 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KUM65013.1 - 0.00011 22.0 2.7 0.0038 17.0 1.3 3.1 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain GSHPx PF00255.19 KUM65013.1 - 0.069 12.7 0.0 17 5.1 0.0 2.5 2 0 0 2 2 2 0 Glutathione peroxidase DEAD PF00270.29 KUM65014.1 - 1.8e-45 154.9 0.0 2.5e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM65014.1 - 8.8e-29 100.1 0.0 2.4e-28 98.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KUM65014.1 - 5.1e-05 22.6 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KUM65014.1 - 0.00085 19.4 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Brix PF04427.18 KUM65015.1 - 1.9e-50 171.6 0.6 2.8e-50 171.1 0.6 1.2 1 0 0 1 1 1 1 Brix domain MoeA_N PF03453.17 KUM65016.1 - 4.1e-33 114.4 0.9 6.4e-33 113.7 0.9 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 KUM65016.1 - 1.3e-27 96.3 0.0 5.6e-13 48.8 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_C PF03454.15 KUM65016.1 - 1.5e-10 41.1 0.1 6.3e-10 39.1 0.1 2.2 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) Acetyltransf_10 PF13673.7 KUM65019.1 - 0.081 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KUM65020.1 - 1.7e-39 135.8 30.8 1.7e-39 135.8 30.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM65020.1 - 4.3e-14 52.2 12.3 4.3e-14 52.2 12.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KUM65020.1 - 2.3e-08 33.0 5.7 3.8e-08 32.2 5.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KUM65020.1 - 0.0081 14.6 7.7 0.029 12.8 5.3 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector G0-G1_switch_2 PF15103.6 KUM65020.1 - 0.36 11.3 1.3 13 6.3 0.0 2.8 3 0 0 3 3 3 0 G0/G1 switch protein 2 Snf7 PF03357.21 KUM65021.1 - 1.1e-33 116.3 19.2 1.1e-33 116.3 19.2 2.0 1 1 1 2 2 2 1 Snf7 Calici_MSP PF05752.11 KUM65021.1 - 1.9 8.3 6.9 2.7 7.8 5.9 1.8 1 1 0 1 1 1 0 Calicivirus minor structural protein DUF3138 PF11336.8 KUM65021.1 - 4.4 5.8 8.8 6.4 5.3 8.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) NuA4 PF09340.10 KUM65021.1 - 7 6.6 8.4 0.48 10.3 0.3 2.9 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 Aconitase PF00330.20 KUM65022.1 - 1.5e-144 482.5 0.0 1.8e-144 482.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KUM65022.1 - 1.1e-38 132.5 0.0 1.7e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain TMEM52 PF14979.6 KUM65023.1 - 0.12 12.3 1.2 0.13 12.2 1.2 1.1 1 0 0 1 1 1 0 Transmembrane 52 zf-C2H2 PF00096.26 KUM65024.1 - 2.2e-12 46.7 12.6 4.2e-06 26.9 2.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KUM65024.1 - 8.1e-12 45.0 9.7 2.1e-07 31.0 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KUM65024.1 - 1.3e-08 35.0 10.4 0.00047 20.8 1.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KUM65024.1 - 5e-08 32.8 5.4 0.00037 20.4 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KUM65024.1 - 5e-06 26.6 0.4 0.1 12.9 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KUM65024.1 - 8.3e-05 22.8 1.5 0.015 15.7 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KUM65024.1 - 0.008 15.9 4.8 0.47 10.3 0.7 3.4 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-Di19 PF05605.12 KUM65024.1 - 0.1 12.9 1.4 0.21 11.9 1.4 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.6 KUM65024.1 - 0.22 12.1 0.9 0.48 11.0 0.9 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain LIM PF00412.22 KUM65024.1 - 0.91 9.8 3.1 21 5.5 0.2 2.5 1 1 1 2 2 2 0 LIM domain C5HCH PF17982.1 KUM65024.1 - 6.7 7.0 6.0 32 4.8 0.4 2.6 1 1 1 2 2 2 0 NSD Cys-His rich domain PQ-loop PF04193.14 KUM65025.1 - 6.1e-38 128.4 7.6 1.2e-19 69.8 0.5 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 KUM65025.1 - 0.099 12.7 2.7 0.23 11.5 0.0 2.4 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Tcf25 PF04910.14 KUM65026.1 - 4.9e-75 252.8 0.0 6.3e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 PGA2 PF07543.12 KUM65026.1 - 0.47 10.4 13.8 0.86 9.6 13.8 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Stm1_N PF09598.10 KUM65026.1 - 1.6 9.7 15.3 0.92 10.4 12.1 2.3 1 1 1 2 2 2 0 Stm1 SWIRM-assoc_2 PF16496.5 KUM65026.1 - 1.7 7.4 10.4 2.7 6.8 10.4 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal CDC45 PF02724.14 KUM65026.1 - 2.6 6.2 7.5 3.4 5.8 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2408 PF10303.9 KUM65027.1 - 1.2e-44 152.2 8.9 1.8e-28 99.8 1.6 5.2 3 2 1 4 4 4 3 Protein of unknown function (DUF2408) Spc7 PF08317.11 KUM65027.1 - 0.00036 19.5 0.7 0.00079 18.4 0.7 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein FPP PF05911.11 KUM65027.1 - 0.004 15.4 0.9 0.0055 15.0 0.9 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil ABC_tran_CTD PF16326.5 KUM65027.1 - 0.027 14.7 3.4 9.4 6.6 0.0 4.1 4 0 0 4 4 4 0 ABC transporter C-terminal domain DUF2383 PF09537.10 KUM65027.1 - 0.071 13.4 0.2 0.21 12.0 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) DUF4795 PF16043.5 KUM65027.1 - 0.12 12.0 1.3 0.89 9.1 1.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Snapin_Pallidin PF14712.6 KUM65027.1 - 0.14 12.6 6.9 0.27 11.7 0.4 4.0 5 0 0 5 5 5 0 Snapin/Pallidin DUF3659 PF12396.8 KUM65027.1 - 0.17 11.9 0.2 0.79 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Baculo_PEP_C PF04513.12 KUM65027.1 - 0.33 11.0 1.9 0.65 10.0 1.0 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 KUM65027.1 - 1.5 9.0 6.7 0.48 10.6 3.3 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Ribosomal_60s PF00428.19 KUM65028.1 - 2.4e-25 88.9 8.7 3.2e-25 88.5 8.7 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_L27e PF01777.18 KUM65029.1 - 9.1e-37 125.3 1.1 1.4e-36 124.7 1.1 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KUM65029.1 - 0.0054 16.6 3.0 0.0089 15.9 1.5 2.1 2 0 0 2 2 2 1 KOW motif SAP30_Sin3_bdg PF13867.6 KUM65030.1 - 0.001 19.3 0.4 3.7 7.9 0.0 4.9 4 0 0 4 4 4 1 Sin3 binding region of histone deacetylase complex subunit SAP30 ATG16 PF08614.11 KUM65030.1 - 0.0087 16.3 1.3 0.0087 16.3 1.3 8.1 7 2 3 10 10 10 1 Autophagy protein 16 (ATG16) Proteasome PF00227.26 KUM65030.1 - 0.042 13.3 2.4 4.7 6.7 0.1 4.4 3 1 1 4 4 4 0 Proteasome subunit Dynein_light PF01221.18 KUM65030.1 - 0.19 12.1 0.4 15 6.0 0.1 4.4 2 0 0 2 2 2 0 Dynein light chain type 1 Chalcone_3 PF16036.5 KUM65030.1 - 1 9.4 11.5 5.1 7.2 0.3 6.3 2 1 0 4 4 4 0 Chalcone isomerase-like Scaffolding_pro PF11418.8 KUM65030.1 - 1.2 9.7 6.8 0.97 10.0 1.2 4.0 3 0 0 3 3 3 0 Phi29 scaffolding protein adh_short PF00106.25 KUM65031.1 - 1.5e-31 109.4 0.0 2.2e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM65031.1 - 6e-23 81.6 0.0 1e-22 80.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM65031.1 - 5.9e-10 39.4 0.1 1.1e-09 38.4 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KUM65031.1 - 0.026 13.9 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) PHD PF00628.29 KUM65032.1 - 1.7e-08 34.2 7.1 3.1e-08 33.4 7.1 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KUM65032.1 - 0.0025 17.7 3.2 0.0054 16.6 3.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 Cytochrom_c3_2 PF14537.6 KUM65032.1 - 0.041 14.3 4.8 0.56 10.7 0.1 2.6 2 0 0 2 2 2 0 Cytochrome c3 US2 PF02476.15 KUM65032.1 - 1.9 9.2 5.7 0.38 11.4 0.2 2.6 3 0 0 3 3 3 0 US2 family CoA_transf_3 PF02515.17 KUM65033.1 - 1.4e-128 429.1 0.0 1.6e-128 428.9 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III GxDLY PF14607.6 KUM65033.1 - 0.13 12.1 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 N-terminus of Esterase_SGNH_hydro-type Lum_binding PF00677.17 KUM65034.1 - 6e-43 144.7 1.4 5.9e-22 77.5 0.4 2.2 2 0 0 2 2 2 2 Lumazine binding domain TRAM_LAG1_CLN8 PF03798.16 KUM65035.1 - 1.1e-54 185.2 15.2 1.1e-54 185.2 15.2 1.4 2 0 0 2 2 2 1 TLC domain SWIB PF02201.18 KUM65036.1 - 1.7e-23 82.3 0.0 3e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain RPN6_N PF18055.1 KUM65037.1 - 4.3e-42 143.2 0.9 3.3e-41 140.3 0.1 2.7 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KUM65037.1 - 1.5e-21 76.9 1.6 2.9e-21 76.0 0.2 2.2 2 1 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KUM65037.1 - 2e-11 43.4 0.1 5e-11 42.1 0.1 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 KUM65037.1 - 4.6e-05 23.6 19.8 0.069 13.5 6.3 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat DDRGK PF09756.9 KUM65037.1 - 5.3e-05 22.9 0.6 9.8e-05 22.0 0.6 1.4 1 0 0 1 1 1 1 DDRGK domain HTH_Crp_2 PF13545.6 KUM65037.1 - 0.0014 18.6 0.1 0.41 10.7 0.0 2.9 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain TPR_MalT PF17874.1 KUM65037.1 - 0.004 16.6 7.2 0.004 16.6 7.2 2.2 2 1 0 2 2 2 1 MalT-like TPR region DUF410 PF04190.13 KUM65037.1 - 0.007 16.2 0.1 0.007 16.2 0.1 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF410) DprA_WH PF17782.1 KUM65037.1 - 0.059 13.5 1.1 0.43 10.7 0.0 2.9 3 1 0 3 3 3 0 DprA winged helix domain Soyouz_module PF14313.6 KUM65037.1 - 0.064 13.0 0.1 0.39 10.5 0.0 2.4 3 0 0 3 3 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) TPR_7 PF13176.6 KUM65037.1 - 0.074 13.1 5.7 9.4 6.5 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Prefoldin_2 PF01920.20 KUM65037.1 - 0.089 12.8 2.5 0.15 12.0 0.6 2.4 2 0 0 2 2 2 0 Prefoldin subunit TPR_2 PF07719.17 KUM65037.1 - 0.18 12.0 12.4 9 6.7 0.1 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KUM65037.1 - 0.21 12.5 11.6 53 5.0 0.7 6.0 4 2 2 6 6 6 0 Tetratricopeptide repeat DUF4398 PF14346.6 KUM65037.1 - 0.4 11.3 9.3 1.6 9.4 1.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) TPR_1 PF00515.28 KUM65037.1 - 0.96 9.4 10.7 1.8 8.5 0.1 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 KUM65037.1 - 6.6 7.2 11.9 19 5.8 0.0 5.1 6 1 1 7 7 5 0 Tetratricopeptide repeat Sof1 PF04158.14 KUM65038.1 - 1e-30 105.8 15.3 1.9e-30 104.9 15.3 1.5 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KUM65038.1 - 2e-30 104.4 3.3 8.5e-06 26.4 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM65038.1 - 7.5e-09 35.8 0.2 0.067 13.5 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KUM65038.1 - 1e-05 24.7 0.1 0.022 13.7 0.0 2.9 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KUM65038.1 - 0.00056 19.8 0.7 0.0048 16.8 0.1 2.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KUM65038.1 - 0.0022 16.4 0.0 0.011 14.1 0.0 2.0 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF1481 PF07356.12 KUM65038.1 - 0.074 12.8 0.0 0.24 11.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) Pkinase PF00069.25 KUM65039.1 - 3.1e-69 233.3 0.0 4.2e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM65039.1 - 9.7e-31 107.0 0.0 1.5e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KUM65039.1 - 3.6e-13 50.0 0.3 3.6e-13 50.0 0.3 3.0 3 1 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.6 KUM65039.1 - 7.2e-09 35.4 0.1 6.3e-08 32.3 0.0 2.0 1 1 0 2 2 2 1 Kinase-like C2 PF00168.30 KUM65039.1 - 2.1e-08 34.4 0.0 4.4e-07 30.1 0.0 2.5 2 0 0 2 2 2 1 C2 domain Haspin_kinase PF12330.8 KUM65039.1 - 2.1e-05 23.7 0.1 3.7e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KUM65039.1 - 0.0056 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Adeno_E3_15_3 PF03307.14 KUM65039.1 - 0.027 14.4 0.1 0.05 13.5 0.1 1.3 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region Choline_kinase PF01633.20 KUM65039.1 - 0.065 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KUM65039.1 - 0.12 11.7 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CRC_subunit PF08624.10 KUM65040.1 - 3.6e-51 173.1 0.0 5.1e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit NADHdh_A3 PF14987.6 KUM65040.1 - 1.6 9.1 3.4 19 5.7 0.1 2.9 3 0 0 3 3 3 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 tRNA-synt_1c PF00749.21 KUM65041.1 - 1.8e-102 342.4 0.0 2.4e-102 342.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KUM65041.1 - 1.9e-31 109.3 0.0 6.7e-31 107.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain THUMP PF02926.17 KUM65041.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 THUMP domain F-box-like PF12937.7 KUM65042.1 - 0.0041 17.0 0.1 0.016 15.1 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KUM65042.1 - 0.052 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 F-box domain LRR_8 PF13855.6 KUM65042.1 - 0.077 12.8 2.6 0.3 10.9 2.6 2.0 1 0 0 1 1 1 0 Leucine rich repeat TauD PF02668.16 KUM65043.1 - 1.2e-38 133.4 1.6 1.7e-38 133.0 1.6 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KUM65043.1 - 3.3e-12 46.9 0.2 6.3e-12 46.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KUM65043.1 - 0.0057 15.8 0.1 0.018 14.2 0.1 1.8 1 1 0 1 1 1 1 CsiD AAA PF00004.29 KUM65044.1 - 1.3e-40 138.9 0.0 2.6e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KUM65044.1 - 7.9e-19 67.4 0.2 1.6e-18 66.4 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KUM65044.1 - 1.7e-09 37.3 0.0 3.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KUM65044.1 - 5.8e-05 23.1 0.1 0.00028 20.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KUM65044.1 - 6.4e-05 22.7 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KUM65044.1 - 0.00017 22.0 1.3 0.022 15.1 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KUM65044.1 - 0.0022 18.1 1.5 0.012 15.7 0.0 2.9 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KUM65044.1 - 0.004 16.4 0.0 0.011 14.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KUM65044.1 - 0.0051 17.1 2.0 0.2 11.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain PhoH PF02562.16 KUM65044.1 - 0.0052 16.3 0.2 0.079 12.4 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KUM65044.1 - 0.0083 15.5 0.0 0.021 14.2 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KUM65044.1 - 0.014 15.5 0.0 0.043 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KUM65044.1 - 0.07 12.9 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KUM65044.1 - 0.078 12.7 0.1 0.32 10.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain JIP_LZII PF16471.5 KUM65044.1 - 0.24 11.6 6.0 0.61 10.3 6.0 1.7 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II AAA_11 PF13086.6 KUM65044.1 - 0.47 10.2 0.0 0.47 10.2 0.0 2.8 2 1 0 3 3 2 0 AAA domain Atg14 PF10186.9 KUM65044.1 - 0.83 8.7 5.9 2.7 7.0 5.4 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CLZ PF16526.5 KUM65044.1 - 2.9 8.3 11.4 0.62 10.5 6.8 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Methyltransf_25 PF13649.6 KUM65045.1 - 1.2e-12 48.4 0.0 2.8e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM65045.1 - 2.3e-11 43.7 0.0 4.8e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KUM65045.1 - 1.3e-10 41.2 0.0 1.9e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KUM65045.1 - 5.4e-09 36.6 0.0 1.9e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM65045.1 - 5.5e-08 32.8 0.0 6.8e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KUM65045.1 - 2.8e-06 26.5 0.1 4.9e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 KUM65045.1 - 4.1e-05 23.0 0.0 6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KUM65045.1 - 9.6e-05 22.4 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KUM65045.1 - 0.00019 21.0 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KUM65045.1 - 0.00052 20.7 0.0 0.001 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KUM65045.1 - 0.0015 18.6 0.0 0.0043 17.2 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KUM65045.1 - 0.0064 16.2 0.0 0.0097 15.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PRMT5 PF05185.16 KUM65045.1 - 0.0079 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 KUM65045.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KUM65045.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 KUM65045.1 - 0.015 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KUM65045.1 - 0.022 14.5 0.2 0.039 13.7 0.2 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 KUM65045.1 - 0.098 13.7 0.0 0.21 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MaoC_dehydratas PF01575.19 KUM65046.1 - 1.4e-22 79.5 0.0 2.7e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KUM65046.1 - 5.4e-06 26.6 0.0 0.012 15.8 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase PGM_PMM_I PF02878.16 KUM65047.1 - 3.4e-16 59.2 0.1 3.1e-07 30.2 0.0 2.8 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KUM65047.1 - 2.2e-11 43.8 0.9 8.1e-11 41.9 0.3 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KUM65047.1 - 0.00098 19.3 0.2 0.0052 17.0 0.2 2.1 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KUM65047.1 - 0.0013 19.4 0.9 0.011 16.3 0.6 2.7 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Per1 PF04080.13 KUM65048.1 - 5.6e-102 340.9 16.3 6.8e-102 340.6 16.3 1.1 1 0 0 1 1 1 1 Per1-like family NmrA PF05368.13 KUM65049.1 - 9.5e-11 41.7 0.0 1.3e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM65049.1 - 0.0085 16.0 0.0 0.017 15.0 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Ribosomal_L30_N PF08079.12 KUM65049.1 - 0.18 12.0 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Pescadillo_N PF06732.11 KUM65050.1 - 3.1e-124 414.0 0.0 3.1e-124 414.0 0.0 1.6 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KUM65050.1 - 6.9e-05 23.2 0.0 0.00044 20.6 0.0 2.3 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Astro_capsid_p PF12226.8 KUM65050.1 - 0.00046 19.4 11.0 0.00046 19.4 11.0 2.2 2 0 0 2 2 2 1 Turkey astrovirus capsid protein BRCT PF00533.26 KUM65050.1 - 0.021 15.2 0.0 0.15 12.4 0.0 2.5 3 1 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KUM65050.1 - 0.034 14.4 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain PIG-U PF06728.13 KUM65051.1 - 3.5e-122 408.1 22.9 4e-122 407.9 22.9 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.13 KUM65051.1 - 4.9e-05 23.3 0.1 9.3e-05 22.4 0.1 1.5 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) 8TM_micro PF17028.5 KUM65051.1 - 1.5 8.4 7.5 5.7 6.6 7.5 1.9 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain Acetyltransf_1 PF00583.25 KUM65052.1 - 1.2e-14 54.5 0.0 1.7e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KUM65052.1 - 1.3e-07 31.9 0.1 2e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KUM65052.1 - 2.2e-07 30.9 0.0 3.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KUM65052.1 - 1.1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KUM65052.1 - 0.084 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Tgi2PP PF18250.1 KUM65052.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Effector immunity protein Tgi2PP Acetyltransf_3 PF13302.7 KUM65052.1 - 0.2 12.3 0.0 0.33 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ADH_zinc_N PF00107.26 KUM65053.1 - 7.1e-26 90.7 0.3 1.2e-25 90.0 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM65053.1 - 9.9e-16 59.0 0.0 2.2e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM65053.1 - 3.2e-11 43.1 0.0 1.2e-10 41.2 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KUM65053.1 - 0.0004 20.6 0.0 0.0008 19.6 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 KUM65053.1 - 0.023 14.0 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Raffinose_syn PF05691.12 KUM65054.1 - 1.2e-49 168.9 3.4 2.2e-47 161.4 1.4 3.5 2 1 1 3 3 3 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.18 KUM65054.1 - 0.00021 20.4 0.1 0.00033 19.7 0.1 1.2 1 0 0 1 1 1 1 Melibiase tRNA-synt_1b PF00579.25 KUM65055.1 - 7.4e-71 238.9 0.0 9.9e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KUM65055.1 - 1.3e-46 157.3 0.0 3e-46 156.1 0.0 1.6 2 0 0 2 2 2 1 Tyrosyl-tRNA synthetase C-terminal domain MutS_V PF00488.21 KUM65056.1 - 8.9e-68 228.0 0.1 1.5e-67 227.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KUM65056.1 - 1.3e-40 139.7 0.0 2.8e-40 138.6 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KUM65056.1 - 8.4e-33 113.0 0.1 2e-32 111.8 0.0 1.7 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KUM65056.1 - 2e-15 57.3 0.0 5.2e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KUM65056.1 - 2.2e-13 50.3 0.3 4.6e-13 49.3 0.3 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.6 KUM65056.1 - 0.089 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KUM65056.1 - 0.15 11.3 0.6 0.49 9.6 0.0 2.1 3 0 0 3 3 3 0 Zeta toxin AAA_23 PF13476.6 KUM65056.1 - 0.71 10.3 0.0 0.71 10.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain Astro_capsid_p PF12226.8 KUM65058.1 - 0.063 12.4 4.8 0.062 12.4 4.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RNA_pol_3_Rpc31 PF11705.8 KUM65058.1 - 0.16 12.2 7.8 0.16 12.2 7.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 KUM65058.1 - 5.5 5.0 10.1 5.6 4.9 10.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi mRNA_triPase PF02940.15 KUM65059.1 - 4.4e-61 206.4 0.1 6.3e-61 205.9 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Acyl_transf_3 PF01757.22 KUM65060.1 - 2.1e-30 106.0 41.6 3.7e-30 105.1 41.6 1.5 1 1 0 1 1 1 1 Acyltransferase family DUF4395 PF14340.6 KUM65060.1 - 0.22 11.8 0.0 0.22 11.8 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4395) Fungal_trans_2 PF11951.8 KUM65061.1 - 4.9e-09 35.5 0.2 0.00016 20.6 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Glyco_hydro_6 PF01341.17 KUM65062.1 - 0.2 11.3 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 His_Phos_2 PF00328.22 KUM65064.1 - 1.1e-70 238.9 0.0 1.4e-70 238.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) WD40 PF00400.32 KUM65065.1 - 2.6e-13 50.2 7.3 5.8e-05 23.8 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat CTP_transf_like PF01467.26 KUM65066.1 - 5.9e-05 23.3 0.0 0.00022 21.5 0.0 1.9 1 1 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KUM65066.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 FAD synthetase PQ-loop PF04193.14 KUM65069.1 - 2.6e-21 75.2 8.1 9.6e-11 41.3 1.2 2.8 3 0 0 3 3 3 2 PQ loop repeat DoxX_3 PF13781.6 KUM65069.1 - 0.021 15.4 1.4 0.021 15.4 1.4 1.9 2 0 0 2 2 2 0 DoxX-like family Med8 PF10232.9 KUM65070.1 - 8.9e-63 212.0 0.2 9.9e-63 211.8 0.2 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF575 PF04746.12 KUM65071.1 - 0.075 13.3 0.2 0.21 11.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF575) EphA2_TM PF14575.6 KUM65071.1 - 0.26 12.2 5.8 3.8 8.5 5.8 2.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.8 KUM65071.1 - 8.8 7.0 21.0 9.3e+02 0.5 21.0 2.3 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF4072 PF13284.6 KUM65072.1 - 0.055 13.9 0.1 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) EphA2_TM PF14575.6 KUM65074.1 - 0.071 14.0 0.0 0.17 12.8 0.0 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PMI_typeI PF01238.21 KUM65075.1 - 7.3e-33 114.3 0.0 2.7e-31 109.1 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KUM65075.1 - 6.8e-05 22.5 0.1 0.27 11.0 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KUM65075.1 - 0.0061 16.5 0.1 10 6.0 0.0 3.1 2 1 1 3 3 3 2 AraC-like ligand binding domain Cupin_3 PF05899.12 KUM65075.1 - 0.12 12.1 0.1 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) tRNA-synt_2 PF00152.20 KUM65077.1 - 1e-89 300.7 0.0 1.4e-89 300.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KUM65077.1 - 2.4e-05 24.2 0.0 4.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.25 KUM65077.1 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) TauD PF02668.16 KUM65077.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family ABC_tran PF00005.27 KUM65078.1 - 5e-47 159.9 0.0 5.5e-30 104.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KUM65078.1 - 3e-38 132.0 33.2 1.4e-25 90.5 10.4 3.6 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 KUM65078.1 - 5.4e-10 39.1 0.0 0.039 13.4 0.0 4.5 4 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KUM65078.1 - 0.00025 21.5 0.7 0.091 13.1 0.1 3.0 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KUM65078.1 - 0.00047 20.2 0.4 0.082 13.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KUM65078.1 - 0.00086 19.6 0.1 1.9 8.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 KUM65078.1 - 0.0012 17.9 0.0 0.26 10.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.17 KUM65078.1 - 0.0024 18.0 0.7 0.82 9.7 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 KUM65078.1 - 0.003 17.5 0.3 3.6 7.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KUM65078.1 - 0.0038 16.9 0.8 1.9 8.3 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF2075 PF09848.9 KUM65078.1 - 0.014 14.7 0.2 0.18 11.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_21 PF13304.6 KUM65078.1 - 0.036 13.9 0.2 7.8 6.2 0.0 3.5 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KUM65078.1 - 0.056 13.9 0.5 6 7.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KUM65078.1 - 0.079 12.5 0.0 6.1 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KUM65078.1 - 0.11 12.2 0.0 1 9.1 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein MeaB PF03308.16 KUM65078.1 - 0.11 11.4 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 KUM65078.1 - 0.15 11.3 0.0 11 5.1 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain LigD_N PF13298.6 KUM65079.1 - 9.9e-37 125.4 0.0 2.2e-36 124.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) FAD_binding_4 PF01565.23 KUM65080.1 - 1.4e-27 96.2 2.0 2.9e-27 95.1 2.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KUM65080.1 - 3.8e-11 42.9 0.0 9.1e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Sulf_transp PF04143.14 KUM65081.1 - 1e-06 28.6 9.8 3.9e-06 26.6 1.3 3.2 3 0 0 3 3 3 2 Sulphur transport Peptidase_M28 PF04389.17 KUM65082.1 - 2.9e-31 108.7 0.0 3.6e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 DUF4674 PF15719.5 KUM65084.1 - 1.3 9.0 6.9 0.16 12.0 2.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4674) UbiA PF01040.18 KUM65085.1 - 1.6e-55 188.2 16.4 1.6e-55 188.2 16.4 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family Cutinase PF01083.22 KUM65086.1 - 6.8e-45 153.2 1.6 8.4e-45 152.9 1.6 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KUM65086.1 - 0.0015 18.1 0.2 0.0024 17.5 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 KUM65086.1 - 0.0068 16.2 0.0 0.016 15.0 0.0 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KUM65086.1 - 0.096 12.3 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM65086.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 VirJ PF06057.11 KUM65086.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) APH PF01636.23 KUM65087.1 - 6.7e-06 26.2 0.1 1e-05 25.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.16 KUM65088.1 - 6.4e-35 120.7 14.9 6.4e-35 120.7 14.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM65088.1 - 5.9e-10 38.6 8.4 5.9e-10 38.6 8.4 2.9 3 1 0 3 3 3 1 Sugar (and other) transporter BT1 PF03092.16 KUM65088.1 - 0.0031 15.8 2.2 0.0031 15.8 2.2 1.5 2 0 0 2 2 2 1 BT1 family DAO PF01266.24 KUM65089.1 - 1.4e-31 110.3 2.4 1.7e-31 110.1 2.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KUM65089.1 - 0.0046 17.0 0.1 0.18 11.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KUM65089.1 - 0.0076 16.5 0.2 0.02 15.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM65089.1 - 0.027 13.7 0.1 0.05 12.8 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM65089.1 - 0.091 11.9 0.0 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KUM65089.1 - 0.11 11.7 0.0 0.26 10.5 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amidase PF01425.21 KUM65090.1 - 1.1e-102 344.4 0.1 3.4e-102 342.7 0.1 1.7 1 1 0 1 1 1 1 Amidase CTD PF12815.7 KUM65091.1 - 7.6e-20 71.3 31.7 5.8e-18 65.2 17.9 3.9 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.8 KUM65091.1 - 6.1e-18 65.6 11.1 6.1e-18 65.6 11.1 3.9 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 KUM65091.1 - 2.5e-16 59.3 0.0 4.2e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KUM65091.1 - 2.2e-10 40.1 11.7 0.0037 17.2 0.4 4.2 4 0 0 4 4 4 3 KOW motif DUF3912 PF13051.6 KUM65091.1 - 0.0058 16.9 0.4 2.4 8.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3912) TFIIF_alpha PF05793.12 KUM65091.1 - 2.5 6.6 37.5 3.7 6.0 37.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ank_2 PF12796.7 KUM65092.1 - 1.9e-06 28.3 0.0 0.36 11.5 0.0 3.7 2 2 3 5 5 5 3 Ankyrin repeats (3 copies) MiaE_2 PF13794.6 KUM65092.1 - 0.054 13.2 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like ArdA PF07275.11 KUM65092.1 - 0.16 12.5 0.2 0.44 11.1 0.0 1.7 2 0 0 2 2 2 0 Antirestriction protein (ArdA) Acyl-CoA_dh_1 PF00441.24 KUM65093.1 - 3.8e-41 140.8 0.4 5.3e-41 140.3 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KUM65093.1 - 6.7e-22 77.5 0.1 1.2e-21 76.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KUM65093.1 - 2.8e-19 69.8 0.0 6.5e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 KUM65093.1 - 5.8e-19 68.0 0.2 1.1e-18 67.1 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 KUM65093.1 - 3.7e-08 33.7 0.0 5.4e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain C6 PF01681.17 KUM65093.1 - 0.17 12.4 0.1 0.48 11.0 0.1 1.8 2 0 0 2 2 2 0 C6 domain DEC-1_N PF04625.13 KUM65093.1 - 4.8 6.1 7.1 8.3 5.3 7.1 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RPN2_C PF18004.1 KUM65094.1 - 3e-56 189.8 8.2 3e-56 189.8 8.2 2.7 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KUM65094.1 - 2.6e-35 119.1 21.2 7.9e-10 38.7 0.1 8.5 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KUM65094.1 - 1e-21 77.1 0.0 1.8e-14 53.9 0.0 4.8 3 1 0 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 KUM65094.1 - 3.1e-06 27.6 0.1 0.001 19.5 0.0 4.8 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.22 KUM65094.1 - 5e-05 23.2 0.0 12 6.4 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 KUM65094.1 - 0.023 14.7 3.6 0.26 11.3 0.0 3.2 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KUM65094.1 - 0.033 14.8 2.1 1.1 10.2 0.0 4.0 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat FMN_red PF03358.15 KUM65094.1 - 0.15 11.8 0.2 6.1 6.6 0.0 3.1 3 0 0 3 3 3 0 NADPH-dependent FMN reductase Fez1 PF06818.15 KUM65095.1 - 0.00072 20.1 3.6 0.0012 19.3 3.6 1.3 1 0 0 1 1 1 1 Fez1 Seryl_tRNA_N PF02403.22 KUM65095.1 - 0.016 15.4 3.9 0.035 14.3 2.1 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 KUM65095.1 - 0.017 15.1 2.4 0.14 12.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Paralemmin PF03285.15 KUM65095.1 - 0.026 14.1 0.6 0.062 12.9 0.6 1.6 1 0 0 1 1 1 0 Paralemmin DUF3189 PF11385.8 KUM65095.1 - 0.035 13.9 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) Phage_GP20 PF06810.11 KUM65095.1 - 0.049 13.4 1.5 0.1 12.4 1.5 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 FlaC_arch PF05377.11 KUM65095.1 - 0.063 13.7 0.4 0.23 11.9 0.4 2.0 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF724 PF05266.14 KUM65095.1 - 0.07 13.0 3.2 0.2 11.5 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 KUM65095.1 - 0.084 13.1 0.4 0.25 11.5 0.4 1.9 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CLZ PF16526.5 KUM65095.1 - 0.48 10.8 4.5 0.2 12.0 0.6 2.5 3 0 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-H PF05837.12 KUM65095.1 - 0.52 10.7 4.6 0.59 10.6 1.3 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) LMBR1 PF04791.16 KUM65095.1 - 0.56 9.1 0.9 0.72 8.7 0.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TMCO5 PF14992.6 KUM65095.1 - 0.79 9.2 5.3 0.19 11.3 2.2 1.5 2 0 0 2 2 2 0 TMCO5 family COG5 PF10392.9 KUM65095.1 - 0.96 9.6 5.5 0.63 10.2 2.4 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF5082 PF16888.5 KUM65095.1 - 1.5 9.1 7.3 2.1 8.7 0.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Abhydrolase_6 PF12697.7 KUM65096.1 - 3.4e-05 24.6 0.1 4.9e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KUM65096.1 - 0.14 11.6 0.1 0.37 10.2 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KUM65096.1 - 0.22 11.1 2.6 5.8 6.5 1.4 2.6 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF3336 PF11815.8 KUM65097.1 - 4.8e-35 120.3 1.1 8.7e-35 119.4 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KUM65097.1 - 2.7e-21 76.7 0.0 5e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase TOM6p PF15184.6 KUM65097.1 - 0.053 13.3 0.0 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit TOM6 homolog Peptidase_M28 PF04389.17 KUM65100.1 - 2.6e-39 135.0 0.1 4.6e-39 134.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KUM65100.1 - 3.1e-10 39.9 2.6 7.5e-10 38.7 2.6 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KUM65100.1 - 0.00097 18.9 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KUM65100.1 - 0.012 14.6 0.0 0.17 10.9 0.0 2.3 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase Abhydrolase_1 PF00561.20 KUM65103.1 - 3.8e-17 62.8 0.2 5.1e-17 62.4 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KUM65103.1 - 5.3e-12 45.5 0.0 7.9e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KUM65103.1 - 7.3e-12 46.4 16.4 2.1e-10 41.6 16.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KUM65103.1 - 0.00011 21.9 0.3 0.001 18.8 0.3 2.0 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KUM65103.1 - 0.0053 16.3 2.1 0.0068 15.9 1.5 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Chlorophyllase2 PF12740.7 KUM65103.1 - 0.014 14.3 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme SRR1 PF07985.12 KUM65104.1 - 1.2e-17 63.7 0.1 3.2e-17 62.3 0.1 1.8 2 0 0 2 2 2 1 SRR1 RRP7 PF12923.7 KUM65104.1 - 0.0081 16.3 0.1 0.021 14.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Troponin-I_N PF11636.8 KUM65104.1 - 7.1 6.7 6.7 2.4 8.2 3.1 2.0 2 0 0 2 2 2 0 Troponin I residues 1-32 PNTB PF02233.16 KUM65106.1 - 4.8e-170 566.4 21.5 4.8e-170 566.4 21.5 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KUM65106.1 - 1.1e-73 247.1 0.1 1.1e-73 247.1 0.1 2.2 2 0 0 2 2 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KUM65106.1 - 1.2e-43 148.7 0.0 2.6e-43 147.6 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KUM65106.1 - 5.6e-30 103.6 4.2 5.6e-30 103.6 4.2 4.6 3 1 0 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KUM65106.1 - 3.9e-05 23.1 0.1 0.13 11.6 0.0 3.1 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 KUM65106.1 - 0.014 15.1 0.3 0.12 12.1 0.3 2.6 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Pyr_redox_2 PF07992.14 KUM65106.1 - 0.028 13.7 0.1 0.058 12.6 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 KUM65106.1 - 0.031 14.3 0.1 0.16 11.9 0.1 2.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GIDA PF01134.22 KUM65106.1 - 0.11 11.5 0.5 0.19 10.8 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KUM65106.1 - 0.44 10.8 2.6 0.41 10.9 0.2 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PRIMA1 PF16101.5 KUM65106.1 - 0.82 9.7 4.1 2.9 7.9 4.1 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 AA_permease_2 PF13520.6 KUM65107.1 - 5.1e-42 144.2 49.3 7.1e-42 143.7 49.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM65107.1 - 3.8e-15 55.5 38.6 5.3e-15 55.0 38.6 1.2 1 0 0 1 1 1 1 Amino acid permease TAF6_C PF07571.13 KUM65109.1 - 2.5e-30 104.6 0.0 6.3e-30 103.4 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KUM65109.1 - 5.2e-24 84.2 0.0 2e-23 82.3 0.1 1.9 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KUM65109.1 - 5.7e-06 26.7 0.4 2.3e-05 24.7 0.3 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KUM65109.1 - 0.0054 16.8 0.1 0.013 15.6 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 KUM65109.1 - 0.05 13.9 0.9 0.11 12.7 0.1 2.0 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SAM_decarbox PF01536.16 KUM65110.1 - 5.2e-132 440.2 0.0 6.2e-132 439.9 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase DUF1327 PF07041.11 KUM65110.1 - 0.12 12.4 0.2 23 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1327) TAFII28 PF04719.14 KUM65111.1 - 5e-25 87.4 1.8 1.5e-23 82.7 0.4 2.2 2 0 0 2 2 2 2 hTAFII28-like protein conserved region Baseplate_J PF04865.14 KUM65111.1 - 0.025 13.7 0.9 0.039 13.1 0.9 1.2 1 0 0 1 1 1 0 Baseplate J-like protein IPP-2 PF04979.14 KUM65113.1 - 7.2e-19 68.8 15.6 7.2e-19 68.8 15.6 2.6 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) MFS_1 PF07690.16 KUM65114.1 - 3.3e-31 108.5 34.0 1.8e-27 96.2 25.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KUM65114.1 - 0.00048 18.7 3.2 0.00048 18.7 3.2 2.4 3 0 0 3 3 3 1 Transmembrane secretion effector MFS_1_like PF12832.7 KUM65114.1 - 0.0031 16.5 1.3 0.0031 16.5 1.3 3.3 3 1 1 4 4 4 2 MFS_1 like family Fumarate_red_D PF02313.17 KUM65114.1 - 0.16 12.1 0.1 0.16 12.1 0.1 3.8 4 0 0 4 4 4 0 Fumarate reductase subunit D CRAL_TRIO PF00650.20 KUM65115.1 - 3.5e-15 56.1 0.0 4.9e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KUM65115.1 - 8.2e-06 25.9 0.0 2.1e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Acyl_transf_3 PF01757.22 KUM65116.1 - 8.1e-18 64.6 27.7 2.2e-17 63.1 27.7 1.9 1 1 0 1 1 1 1 Acyltransferase family 60KD_IMP PF02096.20 KUM65117.1 - 4.7e-22 78.7 1.4 9.3e-22 77.7 1.4 1.5 1 0 0 1 1 1 1 60Kd inner membrane protein Tryp_inh PF17983.1 KUM65119.1 - 0.0057 16.7 0.2 0.013 15.6 0.2 1.6 1 0 0 1 1 1 1 Trypsin inhibitors 1,2 and 3 DUF1752 PF08550.10 KUM65119.1 - 0.059 13.2 0.3 0.13 12.2 0.3 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) MARVEL PF01284.23 KUM65120.1 - 1.1e-07 32.0 1.5 1.1e-07 32.0 1.5 1.7 2 0 0 2 2 2 1 Membrane-associating domain DUF1195 PF06708.11 KUM65120.1 - 0.023 14.5 1.3 0.036 13.8 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) eIF-5a PF01287.20 KUM65123.1 - 0.00099 19.2 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Amidase PF01425.21 KUM65124.1 - 0.0001 21.4 0.0 0.00011 21.3 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF2477 PF10631.9 KUM65125.1 - 7 7.3 8.0 0.43 11.2 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2477) PHD PF00628.29 KUM65126.1 - 4.1e-09 36.2 1.5 8.7e-09 35.1 1.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KUM65126.1 - 0.02 14.5 1.8 0.031 13.8 1.8 1.3 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 KUM65126.1 - 2.8 7.9 4.4 3.1 7.8 0.4 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ELO PF01151.18 KUM65128.1 - 8.2e-61 205.7 23.4 9.5e-61 205.5 23.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family tRNA-synt_1b PF00579.25 KUM65129.1 - 2.3e-55 188.0 0.0 2.9e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) MFS_1 PF07690.16 KUM65130.1 - 2.5e-43 148.4 29.2 2.5e-43 148.4 29.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM65130.1 - 4.9e-10 38.5 2.0 8.6e-10 37.7 2.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM65130.1 - 2.3e-08 33.4 11.8 2.3e-08 33.4 11.8 3.1 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 KUM65130.1 - 0.00031 20.2 0.9 0.00031 20.2 0.9 2.4 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB GATase_5 PF13507.6 KUM65131.1 - 1.9e-98 328.7 0.0 2.8e-98 328.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KUM65131.1 - 7.7e-38 130.1 0.4 2e-24 86.5 0.3 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KUM65131.1 - 2.8e-33 114.3 0.0 5.4e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KUM65131.1 - 3.5e-22 78.7 0.0 8.2e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 KUM65131.1 - 0.047 14.4 0.1 0.23 12.2 0.0 2.3 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain LEA_3 PF03242.13 KUM65131.1 - 0.1 13.3 0.1 0.32 11.7 0.1 1.8 1 0 0 1 1 1 0 Late embryogenesis abundant protein TOM13 PF08219.11 KUM65132.1 - 6.8e-37 125.3 0.1 8.7e-37 125.0 0.1 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 COX5A PF02284.16 KUM65133.1 - 6.8e-37 125.6 0.2 1e-36 125.0 0.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Glyco_transf_15 PF01793.16 KUM65134.1 - 1.2e-112 376.4 5.8 1.3e-112 376.2 5.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_25 PF01755.17 KUM65134.1 - 0.014 15.3 0.4 0.02 14.8 0.4 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) GCP_N_terminal PF17681.1 KUM65135.1 - 2.7e-36 125.7 0.8 2.7e-36 125.7 0.8 2.1 3 1 0 3 3 3 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KUM65135.1 - 7e-25 88.1 3.7 1.4e-24 87.1 3.7 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 KUM65135.1 - 2.6e-13 49.2 0.0 6.3e-13 48.0 0.0 1.6 2 0 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 TB2_DP1_HVA22 PF03134.19 KUM65138.1 - 8e-28 96.2 9.8 8e-28 96.2 9.8 1.6 1 1 1 2 2 2 2 TB2/DP1, HVA22 family Ras PF00071.22 KUM65139.1 - 4.9e-52 175.8 0.0 5.6e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM65139.1 - 4.6e-19 68.8 0.0 6.2e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM65139.1 - 6.1e-10 38.8 0.0 6.6e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KUM65139.1 - 1.7e-05 24.5 0.0 0.00017 21.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KUM65139.1 - 0.00013 22.1 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KUM65139.1 - 0.0017 18.3 0.1 2.1 8.2 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KUM65139.1 - 0.02 15.2 0.3 0.35 11.1 0.2 2.4 2 1 0 2 2 2 0 AAA domain Peroxin-3 PF04882.12 KUM65140.1 - 1.1e-172 575.3 0.3 1.3e-172 575.0 0.3 1.0 1 0 0 1 1 1 1 Peroxin-3 ATG101 PF07855.12 KUM65141.1 - 3.4e-52 176.5 0.0 4e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 CAF1A PF12253.8 KUM65142.1 - 3.1e-20 72.1 7.6 3.1e-20 72.1 7.6 4.2 2 1 1 3 3 3 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.8 KUM65142.1 - 0.00015 21.5 66.0 0.0004 20.1 66.0 1.7 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Borrelia_P83 PF05262.11 KUM65142.1 - 0.0046 15.5 31.8 0.0058 15.2 31.8 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein Raftlin PF15250.6 KUM65142.1 - 2.8 6.6 20.1 4.9 5.8 20.1 1.3 1 0 0 1 1 1 0 Raftlin LAP1C PF05609.12 KUM65142.1 - 5.8 5.9 25.2 11 5.0 25.2 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) THOC7 PF05615.13 KUM65144.1 - 1.2e-43 148.5 6.7 1.2e-43 148.5 6.7 1.9 1 1 1 2 2 2 1 Tho complex subunit 7 Mod_r PF07200.13 KUM65144.1 - 0.017 15.2 8.5 0.033 14.3 8.5 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Peroxin-13_N PF04088.13 KUM65144.1 - 0.12 12.6 0.2 0.27 11.5 0.2 1.7 1 1 0 1 1 1 0 Peroxin 13, N-terminal region FUSC PF04632.12 KUM65144.1 - 1.1 7.7 7.8 1.4 7.3 7.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-H PF05837.12 KUM65144.1 - 4.8 7.6 9.7 8 6.9 6.9 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TBCA PF02970.16 KUM65145.1 - 7.7e-24 83.8 8.4 1.1e-23 83.3 8.4 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor A APC_N_CC PF16689.5 KUM65145.1 - 0.013 15.6 0.4 0.069 13.2 0.2 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Bacillus_HBL PF05791.11 KUM65145.1 - 0.014 15.2 2.4 0.014 15.2 2.4 1.6 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF1910 PF08928.10 KUM65145.1 - 0.044 13.8 2.7 0.085 12.9 2.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) CENP-Q PF13094.6 KUM65145.1 - 0.15 12.2 11.4 1.9 8.7 11.4 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Csm1_N PF18504.1 KUM65145.1 - 0.41 11.0 7.3 0.16 12.4 3.7 2.1 1 1 2 3 3 3 0 Csm1 N-terminal domain Elongin_A PF06881.11 KUM65146.1 - 2.3e-25 89.1 0.2 4e-25 88.4 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A MFS_1 PF07690.16 KUM65147.1 - 2.2e-09 36.7 14.6 2.2e-09 36.7 14.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4203 PF13886.6 KUM65147.1 - 0.0025 17.5 10.3 0.0025 17.5 10.3 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4203) DUF2530 PF10745.9 KUM65147.1 - 0.022 15.0 2.0 0.022 15.0 2.0 2.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2530) MFS_1_like PF12832.7 KUM65147.1 - 0.055 12.3 10.7 0.79 8.5 2.9 2.2 1 1 1 2 2 2 0 MFS_1 like family HOK_GEF PF01848.16 KUM65147.1 - 0.15 11.5 1.6 0.55 9.7 1.5 2.0 2 0 0 2 2 2 0 Hok/gef family FUN14 PF04930.15 KUM65147.1 - 0.57 10.6 3.6 1.5 9.3 3.6 1.7 1 0 0 1 1 1 0 FUN14 family OATP PF03137.20 KUM65147.1 - 0.96 7.7 12.6 0.52 8.5 5.7 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 KUM65148.1 - 2.9e-07 29.3 10.0 3.6e-07 29.0 10.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KUM65148.1 - 8.1e-06 25.0 21.4 8.1e-06 25.0 21.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Pox_A14 PF05767.12 KUM65148.1 - 0.37 11.0 3.2 0.21 11.8 0.6 1.9 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Sulfotransfer_3 PF13469.6 KUM65149.1 - 0.0044 17.4 0.0 0.0091 16.4 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family APH PF01636.23 KUM65150.1 - 5.1e-12 46.2 0.1 1.1e-11 45.2 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acetyltransf_10 PF13673.7 KUM65150.1 - 7.2e-07 29.2 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KUM65150.1 - 0.00045 20.6 0.0 0.00083 19.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM65150.1 - 0.0021 18.3 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Choline_kinase PF01633.20 KUM65150.1 - 0.025 14.2 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase GCV_T PF01571.21 KUM65151.1 - 1.1e-72 244.5 0.0 1.6e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KUM65151.1 - 1.2e-45 156.6 0.7 2.1e-45 155.8 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAO_M PF16350.5 KUM65151.1 - 1.6e-19 70.0 0.0 3e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 KUM65151.1 - 1.7e-19 69.5 0.0 3.6e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_2 PF07992.14 KUM65151.1 - 2.9e-05 23.4 0.0 0.029 13.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM65151.1 - 5.7e-05 23.6 0.0 0.016 15.7 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KUM65151.1 - 0.0018 18.5 0.4 0.0082 16.4 0.1 2.2 3 0 0 3 3 3 1 TrkA-N domain Shikimate_DH PF01488.20 KUM65151.1 - 0.014 15.4 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KUM65151.1 - 0.052 12.9 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 ThiF family NAD_binding_9 PF13454.6 KUM65151.1 - 0.052 13.5 0.2 0.89 9.5 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KUM65151.1 - 0.065 13.5 0.0 0.24 11.6 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KUM65151.1 - 0.083 12.1 0.5 0.77 8.9 0.5 2.1 1 1 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 KUM65151.1 - 0.15 11.1 0.7 0.95 8.5 0.7 2.3 1 1 0 1 1 1 0 FAD binding domain ABATE PF07336.11 KUM65152.1 - 0.033 14.8 2.2 0.062 14.0 0.1 2.4 2 0 0 2 2 2 0 Putative stress-induced transcription regulator WD40 PF00400.32 KUM65154.1 - 2.3e-30 104.2 29.7 2.5e-06 28.1 3.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM65154.1 - 3.9e-17 62.3 0.3 0.00039 20.7 0.0 5.6 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KUM65154.1 - 0.0025 17.7 0.1 0.96 9.3 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KUM65154.1 - 0.063 11.6 0.0 0.19 10.0 0.0 1.6 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Bacteroid_pep PF14406.6 KUM65154.1 - 0.17 12.3 0.0 0.61 10.5 0.0 2.0 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes MBOAT PF03062.19 KUM65155.1 - 2.9e-25 89.4 15.5 5.1e-25 88.5 15.5 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KUM65155.1 - 0.024 14.9 2.8 0.07 13.4 2.8 1.8 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family PseudoU_synth_1 PF01416.20 KUM65156.1 - 7.4e-12 45.7 0.0 7.7e-10 39.2 0.0 2.7 2 0 0 2 2 2 1 tRNA pseudouridine synthase YlbE PF14003.6 KUM65156.1 - 0.11 13.0 0.3 0.33 11.4 0.3 1.8 1 0 0 1 1 1 0 YlbE-like protein Hexapep PF00132.24 KUM65157.1 - 4e-13 48.5 8.6 1.3e-11 43.7 3.7 3.2 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KUM65157.1 - 4.3e-13 48.8 8.0 9.2e-10 38.1 3.4 3.2 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 KUM65157.1 - 2.6e-10 40.4 0.1 4.1e-10 39.7 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase ICMT PF04140.14 KUM65158.1 - 5.9e-28 97.1 0.6 1e-27 96.3 0.6 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KUM65158.1 - 1.4e-10 41.5 2.1 1.4e-10 41.5 2.1 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KUM65158.1 - 8.3e-08 32.0 0.5 1.1e-07 31.6 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Tmemb_170 PF10190.9 KUM65160.1 - 5.1e-10 39.7 6.7 6.7e-10 39.3 6.7 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 SLATT_1 PF18181.1 KUM65160.1 - 0.16 11.9 1.4 0.23 11.4 1.4 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DUF202 PF02656.15 KUM65161.1 - 4e-13 49.6 0.8 4e-13 49.6 0.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) OMPdecase PF00215.24 KUM65163.1 - 1.2e-77 260.5 0.0 1.6e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF72 PF01904.18 KUM65163.1 - 0.029 14.5 0.0 0.066 13.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF72 MAPEG PF01124.18 KUM65164.1 - 9.5e-28 96.7 0.3 1.1e-27 96.5 0.3 1.0 1 0 0 1 1 1 1 MAPEG family DnaJ PF00226.31 KUM65165.1 - 2.4e-24 85.2 2.3 4.1e-24 84.5 2.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KUM65165.1 - 1.2e-23 83.9 0.0 1.8e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KUM65165.1 - 4.2e-15 55.8 15.6 7.1e-15 55.1 15.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KUM65165.1 - 2.4e-06 27.4 5.7 0.01 15.8 0.6 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KUM65165.1 - 0.064 13.3 8.4 2 8.5 2.1 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 KUM65165.1 - 0.19 11.4 8.3 0.39 10.3 0.8 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Lar_restr_allev PF14354.6 KUM65165.1 - 0.2 12.0 9.6 2.4 8.6 1.8 2.9 1 1 2 3 3 3 0 Restriction alleviation protein Lar Cytochrom_c3_2 PF14537.6 KUM65165.1 - 3 8.4 8.2 7.3 7.1 8.2 1.7 1 1 0 1 1 1 0 Cytochrome c3 ketoacyl-synt PF00109.26 KUM65166.1 - 8.6e-67 225.4 0.0 6.7e-66 222.4 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KUM65166.1 - 3e-62 209.7 0.0 7.6e-62 208.4 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KUM65166.1 - 3.3e-61 207.2 0.0 6.1e-61 206.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KUM65166.1 - 7.3e-43 147.3 0.0 1.3e-42 146.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KUM65166.1 - 4.2e-34 117.1 0.0 9.5e-34 116.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KUM65166.1 - 3e-20 72.8 0.0 5e-19 68.9 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KUM65166.1 - 3.5e-14 53.2 0.0 2.2e-11 44.2 0.0 2.7 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 KUM65166.1 - 9.5e-12 45.1 0.0 2.2e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM65166.1 - 3.6e-11 43.6 0.0 3e-10 40.6 0.0 2.8 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM65166.1 - 6.3e-11 42.3 0.0 3.9e-10 39.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 KUM65166.1 - 5.6e-10 39.0 0.0 1.3e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KUM65166.1 - 1e-08 35.2 0.0 3.4e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 KUM65166.1 - 2.5e-08 34.4 0.0 8.2e-08 32.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KUM65166.1 - 3.4e-08 34.6 0.0 2.8e-07 31.7 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NodS PF05401.11 KUM65166.1 - 1e-05 25.3 0.0 2.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) PP-binding PF00550.25 KUM65166.1 - 1.5e-05 25.2 0.1 3.7e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 KUM65166.1 - 0.00024 20.5 0.0 0.00051 19.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KUM65166.1 - 0.00036 20.0 0.0 0.00082 18.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_28 PF02636.17 KUM65166.1 - 0.0036 17.0 0.0 0.062 12.9 0.0 2.3 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.9 KUM65166.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase ADH_N PF08240.12 KUM65166.1 - 0.12 12.3 0.1 0.37 10.7 0.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Clr5 PF14420.6 KUM65167.1 - 5.8e-08 32.8 0.1 1.9e-07 31.2 0.1 2.0 1 0 0 1 1 1 1 Clr5 domain rve PF00665.26 KUM65167.1 - 4.3e-05 23.7 0.2 0.08 13.1 0.0 2.5 2 0 0 2 2 2 2 Integrase core domain Sigma54_DBD PF04552.13 KUM65167.1 - 0.00015 21.5 0.3 0.013 15.2 0.0 2.4 1 1 1 2 2 2 1 Sigma-54, DNA binding domain HTH_Tnp_Tc3_2 PF01498.18 KUM65167.1 - 0.002 18.3 0.6 1.2 9.5 0.1 3.0 2 0 0 2 2 2 2 Transposase Arg_repressor PF01316.21 KUM65167.1 - 0.0087 15.8 0.9 0.59 9.9 0.0 2.5 1 1 1 2 2 2 1 Arginine repressor, DNA binding domain HTH_12 PF08461.10 KUM65167.1 - 0.011 15.7 0.1 3 7.8 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain HTH_32 PF13565.6 KUM65167.1 - 0.014 16.0 4.5 0.29 11.8 0.0 4.0 4 2 1 5 5 5 0 Homeodomain-like domain SapB_2 PF03489.17 KUM65167.1 - 0.05 13.7 0.3 0.2 11.8 0.0 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 2 HTH_21 PF13276.6 KUM65167.1 - 0.07 13.3 2.4 0.39 10.9 0.1 3.0 3 0 0 3 3 3 0 HTH-like domain HTH_33 PF13592.6 KUM65167.1 - 0.41 10.3 2.6 6.4 6.5 0.1 3.1 3 0 0 3 3 3 0 Winged helix-turn helix S4 PF01479.25 KUM65168.1 - 4.1e-14 52.0 0.0 7.6e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KUM65168.1 - 3.4e-11 43.9 2.4 4.5e-11 43.5 2.4 1.4 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Occludin_ELL PF07303.13 KUM65168.1 - 0.047 14.4 0.3 0.14 12.9 0.1 1.9 1 1 1 2 2 2 0 Occludin homology domain DUF5521 PF17659.1 KUM65169.1 - 1.8 6.3 3.6 2.3 5.9 3.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) ADH_zinc_N_2 PF13602.6 KUM65170.1 - 1.6e-13 51.8 0.0 2.6e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KUM65170.1 - 7.5e-11 42.1 0.0 1.4e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM65170.1 - 2.6e-08 33.7 0.0 1.6e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KUM65170.1 - 0.042 14.1 0.1 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KUM65170.1 - 0.084 12.1 0.3 0.13 11.6 0.3 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SnoaL_2 PF12680.7 KUM65171.1 - 6.3e-05 23.6 0.0 8.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF2358 PF10184.9 KUM65171.1 - 0.0079 16.5 0.2 0.013 15.8 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) MFS_1 PF07690.16 KUM65172.1 - 1.1e-38 133.1 23.2 2.3e-38 132.0 21.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Saf_2TM PF18303.1 KUM65172.1 - 0.036 13.6 0.2 1.6 8.3 0.0 2.8 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain MFS_1_like PF12832.7 KUM65172.1 - 0.065 12.1 10.0 0.035 13.0 7.1 1.7 1 1 1 2 2 2 0 MFS_1 like family Trp_oprn_chp PF09534.10 KUM65172.1 - 4.2 7.1 4.8 48 3.7 0.0 3.0 2 2 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4449 PF14613.6 KUM65173.1 - 1.6e-05 25.1 5.1 6.5e-05 23.1 1.1 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) Tricorn_C1 PF14684.6 KUM65173.1 - 0.00078 19.5 0.2 0.016 15.3 0.1 3.0 3 0 0 3 3 3 1 Tricorn protease C1 domain PKHD_C PF18331.1 KUM65173.1 - 0.085 12.9 0.4 2.3 8.3 0.1 3.1 3 0 0 3 3 3 0 PKHD-type hydroxylase C-terminal domain SbsC_C PF18058.1 KUM65173.1 - 1.6 8.9 6.1 1.3 9.3 2.1 2.7 3 0 0 3 3 3 0 SbsC C-terminal domain Beta-lactamase PF00144.24 KUM65174.1 - 2.3e-60 204.6 0.0 3.3e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KUM65174.1 - 6.4e-06 26.6 0.1 1.1e-05 25.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Fungal_trans PF04082.18 KUM65175.1 - 1.6e-30 106.0 0.7 3e-30 105.1 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KUM65176.1 - 1.7e-19 70.0 0.0 2.7e-19 69.4 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM65176.1 - 3.1e-13 49.8 0.0 6.3e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM65176.1 - 5.8e-05 23.1 0.0 8.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 KR domain DBD_Tnp_Mut PF03108.15 KUM65177.1 - 2e-08 34.1 1.7 3.5e-08 33.3 1.7 1.3 1 0 0 1 1 1 1 MuDR family transposase MSA-2c PF12238.8 KUM65177.1 - 3.7 7.5 7.0 9.5 6.2 7.0 1.8 1 0 0 1 1 1 0 Merozoite surface antigen 2c MFS_1 PF07690.16 KUM65178.1 - 3.7e-48 164.2 46.3 1.6e-45 155.6 48.1 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM65178.1 - 2.8e-15 55.8 22.7 9.5e-15 54.0 22.6 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM65178.1 - 2e-10 40.1 12.0 2e-10 40.1 12.0 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter Oxidored_FMN PF00724.20 KUM65179.1 - 2.7e-44 151.8 0.0 3.8e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KUM65179.1 - 0.0011 18.5 0.0 0.066 12.6 0.0 2.3 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel Malic_M PF03949.15 KUM65180.1 - 2e-89 299.3 0.0 2.6e-89 298.9 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KUM65180.1 - 3.6e-63 212.6 0.0 1e-62 211.2 0.0 1.7 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Fungal_trans PF04082.18 KUM65181.1 - 3.3e-27 95.2 0.1 7.4e-27 94.0 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM65181.1 - 3.5e-07 30.2 7.2 8.2e-07 29.0 7.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HLH PF00010.26 KUM65182.1 - 0.0069 16.3 0.4 0.014 15.4 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ank_2 PF12796.7 KUM65183.1 - 1.7e-60 201.6 1.4 4.3e-14 52.8 0.0 5.5 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM65183.1 - 7.7e-40 134.8 5.1 1.9e-10 41.0 0.0 7.6 4 1 4 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KUM65183.1 - 1.7e-38 129.4 7.4 0.00017 21.8 0.0 10.4 11 0 0 11 11 10 8 Ankyrin repeat Ank_3 PF13606.6 KUM65183.1 - 6.9e-37 121.3 1.5 0.0017 18.6 0.0 10.4 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KUM65183.1 - 2.2e-31 107.5 8.0 2.3e-07 30.9 0.0 7.2 4 2 2 7 7 7 4 Ankyrin repeats (many copies) NACHT PF05729.12 KUM65183.1 - 1.5e-07 31.5 0.0 3.7e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain SesA PF17107.5 KUM65183.1 - 0.00052 20.2 2.9 0.0016 18.6 0.8 2.5 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_16 PF13191.6 KUM65183.1 - 0.00078 19.9 0.0 0.0034 17.8 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KUM65183.1 - 0.0048 17.2 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain C1_2 PF03107.16 KUM65183.1 - 0.012 15.9 5.9 0.027 14.8 5.9 1.6 1 0 0 1 1 1 0 C1 domain AAA PF00004.29 KUM65183.1 - 0.055 13.9 0.0 0.27 11.7 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-UDP PF14569.6 KUM65183.1 - 0.06 13.5 3.2 0.13 12.3 3.2 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger NAD_binding_6 PF08030.12 KUM65183.1 - 0.12 12.5 0.1 0.49 10.5 0.0 2.1 2 0 0 2 2 1 0 Ferric reductase NAD binding domain DUF4618 PF15397.6 KUM65183.1 - 0.28 10.6 4.4 0.41 10.0 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) PIN_12 PF16289.5 KUM65183.1 - 0.32 11.5 1.5 3.1 8.2 0.6 2.6 2 1 0 2 2 2 0 PIN domain ZZ PF00569.17 KUM65183.1 - 0.33 10.8 6.5 0.73 9.7 6.5 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type Acyl_transf_3 PF01757.22 KUM65184.1 - 2e-18 66.6 26.4 5.1e-18 65.2 26.4 1.7 1 1 0 1 1 1 1 Acyltransferase family Lipase_GDSL_2 PF13472.6 KUM65186.1 - 8.9e-11 42.5 0.4 1.7e-10 41.6 0.4 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KUM65186.1 - 2.4e-08 34.2 0.0 2.6e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase p450 PF00067.22 KUM65187.1 - 1.1e-57 195.9 0.0 1.4e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DRAT PF07357.11 KUM65187.1 - 0.06 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) TFIIE_alpha PF02002.17 KUM65188.1 - 8.4e-17 60.9 0.0 1.7e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit DUF1849 PF08904.11 KUM65188.1 - 0.051 13.1 0.4 0.095 12.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) DUF3944 PF13099.6 KUM65188.1 - 0.14 12.0 0.3 0.32 10.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) DUF3517 PF12030.8 KUM65189.1 - 1.4e-88 297.0 0.0 2.3e-88 296.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 KUM65189.1 - 3.2e-39 135.0 0.1 5.9e-39 134.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KUM65189.1 - 1.4e-20 74.1 0.6 1.5e-19 70.7 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ADD_ATRX PF17981.1 KUM65189.1 - 0.14 12.1 0.1 0.46 10.4 0.1 1.8 1 0 0 1 1 1 0 Cysteine Rich ADD domain Tyrosinase PF00264.20 KUM65190.1 - 1.4e-51 176.0 0.2 1.7e-51 175.6 0.2 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase FAM196 PF15265.6 KUM65191.1 - 0.65 9.4 23.4 0.74 9.2 23.4 1.1 1 0 0 1 1 1 0 FAM196 family PA26 PF04636.13 KUM65191.1 - 1 8.2 6.7 1.5 7.7 6.7 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Macoilin PF09726.9 KUM65191.1 - 2.6 6.5 22.4 3.1 6.2 22.4 1.2 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 KUM65191.1 - 4.7 7.0 31.4 6.3 6.6 31.4 1.2 1 0 0 1 1 1 0 SPX domain GREB1 PF15782.5 KUM65191.1 - 7 3.6 25.5 8.5 3.3 25.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4551 PF15087.6 KUM65191.1 - 7.1 5.3 22.2 8.7 5.0 22.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) VCBS PF13517.6 KUM65192.1 - 8.9e-31 106.3 43.7 1.7e-12 47.7 2.8 8.3 6 2 3 9 9 9 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 KUM65192.1 - 1.2e-14 55.2 0.6 2.8e-14 53.9 0.6 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KUM65192.1 - 1.8e-11 44.4 0.0 3.5e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 KUM65192.1 - 1.3e-08 34.4 7.3 1.4 8.3 0.0 6.5 5 2 2 7 7 7 4 Insecticide toxin TcdB middle/N-terminal region OSK PF17182.4 KUM65192.1 - 0.0021 17.3 0.1 0.0036 16.6 0.1 1.3 1 0 0 1 1 1 1 OSK domain FG-GAP PF01839.23 KUM65192.1 - 0.013 15.6 38.4 0.15 12.2 0.4 5.6 6 0 0 6 6 6 0 FG-GAP repeat Dockerin_1 PF00404.18 KUM65192.1 - 0.036 14.3 9.1 33 4.8 0.1 6.2 6 0 0 6 6 6 0 Dockerin type I domain PliI PF16743.5 KUM65192.1 - 0.19 11.5 0.1 8.1 6.2 0.0 3.2 4 0 0 4 4 4 0 Periplasmic lysozyme inhibitor of I-type lysozyme Glyco_hydro_72 PF03198.14 KUM65193.1 - 7.3e-136 452.5 4.5 9e-136 452.2 4.5 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KUM65193.1 - 2.3e-05 24.0 0.4 0.032 13.7 0.1 2.3 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Hydantoinase_B PF02538.14 KUM65196.1 - 5.9e-47 160.2 0.0 7e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase SMC_N PF02463.19 KUM65197.1 - 1.1e-62 211.3 30.3 4.3e-61 206.2 30.3 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KUM65197.1 - 1.1e-19 70.8 0.4 1.1e-19 70.8 0.4 3.5 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KUM65197.1 - 1e-09 38.7 8.8 0.00016 21.6 0.1 3.7 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KUM65197.1 - 1.5e-06 28.9 29.7 1.5e-06 28.9 29.7 6.9 2 2 4 6 6 6 1 AAA domain AAA_29 PF13555.6 KUM65197.1 - 0.00014 21.5 0.1 0.00034 20.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain HIP1_clath_bdg PF16515.5 KUM65197.1 - 0.00079 20.0 12.9 0.00079 20.0 12.9 9.5 2 2 8 11 11 11 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Methyltransf_25 PF13649.6 KUM65198.1 - 2.3e-14 53.9 0.0 4.5e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM65198.1 - 6.4e-12 45.3 0.0 1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KUM65198.1 - 3.7e-11 43.5 0.0 7e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM65198.1 - 1.1e-10 41.5 0.0 1.8e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM65198.1 - 3.3e-08 34.2 0.0 5.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM65198.1 - 1.2e-06 28.4 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Flavoprotein PF02441.19 KUM65198.1 - 0.017 14.9 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Flavoprotein MTS PF05175.14 KUM65198.1 - 0.033 13.7 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 KUM65198.1 - 0.067 13.2 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 KUM65198.1 - 0.11 11.9 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain GDI PF00996.18 KUM65199.1 - 1.5e-190 633.4 0.1 1.7e-190 633.1 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KUM65199.1 - 0.027 14.7 0.0 0.088 13.1 0.0 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KUM65199.1 - 0.075 13.6 0.3 0.62 10.7 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 4HBT PF03061.22 KUM65200.1 - 1.3e-12 47.9 0.0 2.1e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KUM65200.1 - 0.00015 22.1 0.0 0.0002 21.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT_2 PF13279.6 KUM65200.1 - 0.059 13.9 0.0 0.089 13.3 0.0 1.3 1 1 0 1 1 1 0 Thioesterase-like superfamily Bac_rhodopsin PF01036.18 KUM65203.1 - 2.9e-16 59.7 16.3 3.9e-16 59.3 16.3 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein ORC4_C PF14629.6 KUM65204.1 - 5.6e-48 163.2 0.0 8.1e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KUM65204.1 - 3.5e-15 56.8 0.1 7.7e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KUM65204.1 - 2.4e-08 34.4 0.0 8.9e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KUM65204.1 - 1.1e-06 28.6 0.0 3.8e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 KUM65204.1 - 2.2e-05 23.8 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.6 KUM65204.1 - 3.7e-05 24.0 0.0 8.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KUM65204.1 - 9.4e-05 22.4 0.0 0.00037 20.5 0.0 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 KUM65204.1 - 0.00021 20.5 0.0 0.00035 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KUM65204.1 - 0.0033 17.7 0.0 0.0059 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KUM65204.1 - 0.008 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ATP-synt_ab PF00006.25 KUM65204.1 - 0.011 15.3 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 KUM65204.1 - 0.024 14.7 0.0 0.071 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KUM65204.1 - 0.031 13.4 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase NB-ARC PF00931.22 KUM65204.1 - 0.032 13.4 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KUM65204.1 - 0.044 14.3 0.0 0.087 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter TniB PF05621.11 KUM65204.1 - 0.19 11.1 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein Astro_capsid_p PF12226.8 KUM65204.1 - 2.5 7.2 6.6 4.3 6.4 6.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Sld5 PF05916.11 KUM65206.1 - 3.3e-34 117.6 0.0 6.4e-34 116.7 0.0 1.5 1 1 0 1 1 1 1 GINS complex protein adh_short PF00106.25 KUM65208.1 - 1.3e-27 96.5 0.0 2.3e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM65208.1 - 1.4e-27 96.8 0.1 3.4e-27 95.5 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM65208.1 - 0.012 15.6 0.0 0.047 13.6 0.0 1.9 1 1 0 1 1 1 0 KR domain Epimerase PF01370.21 KUM65208.1 - 0.04 13.4 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3712 PF12505.8 KUM65209.1 - 4.6e-35 120.6 0.2 1.1e-34 119.4 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) Calycin_like PF13944.6 KUM65209.1 - 0.052 13.9 1.8 0.55 10.5 0.6 2.3 2 0 0 2 2 2 0 Calycin-like beta-barrel domain WD40 PF00400.32 KUM65210.1 - 1.1e-50 168.5 29.4 3.8e-06 27.5 0.2 12.2 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.12 KUM65210.1 - 6.2e-21 74.7 0.2 1.3e-20 73.7 0.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KUM65210.1 - 5e-20 71.6 3.3 0.1 12.9 0.0 9.5 7 3 3 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KUM65210.1 - 2.1e-07 30.3 0.2 0.89 8.4 0.0 5.2 4 2 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KUM65210.1 - 2e-06 26.7 2.6 0.08 11.6 0.0 5.5 5 1 1 6 6 6 2 Nucleoporin Nup120/160 Frtz PF11768.8 KUM65210.1 - 0.0049 15.2 0.0 0.14 10.4 0.0 2.5 2 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KUM65210.1 - 0.0075 15.6 0.0 3.1 7.0 0.0 3.4 3 0 0 3 3 3 1 WD40-like domain Nucleoporin_N PF08801.11 KUM65210.1 - 0.036 12.8 0.6 8.3 5.0 0.0 4.1 2 1 1 4 4 4 0 Nup133 N terminal like Utp13 PF08625.11 KUM65210.1 - 0.14 12.0 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Hira PF07569.11 KUM65210.1 - 0.15 11.8 0.2 5.7 6.6 0.0 3.5 4 0 0 4 4 4 0 TUP1-like enhancer of split P34-Arc PF04045.14 KUM65211.1 - 1.7e-92 309.5 0.0 2.2e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Sel1 PF08238.12 KUM65214.1 - 2.7e-11 43.8 7.5 0.0011 19.6 0.0 3.8 4 0 0 4 4 4 3 Sel1 repeat DUF1776 PF08643.10 KUM65216.1 - 2.1e-104 349.0 0.0 2.6e-104 348.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KUM65216.1 - 1.6e-05 24.4 0.0 8.4e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM65216.1 - 0.065 12.8 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase WLM PF08325.10 KUM65217.1 - 8.6e-64 215.1 0.4 1.3e-63 214.6 0.4 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KUM65217.1 - 0.0012 18.1 3.5 0.0012 18.1 3.5 3.3 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DUF45 PF01863.17 KUM65217.1 - 0.13 12.3 1.8 0.4 10.7 1.8 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF45 DZR PF12773.7 KUM65217.1 - 0.62 10.1 10.2 4.1 7.5 10.2 2.1 1 1 0 1 1 1 0 Double zinc ribbon NOT2_3_5 PF04153.18 KUM65218.1 - 2e-26 92.6 1.7 2.3e-26 92.4 0.0 1.9 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family Nucleo_P87 PF07267.11 KUM65218.1 - 4.4 6.1 4.4 6.4 5.5 4.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MRP-L47 PF06984.13 KUM65219.1 - 1.7e-20 72.9 0.0 2.4e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.12 KUM65219.1 - 0.029 13.8 0.8 0.046 13.2 0.8 1.3 1 0 0 1 1 1 0 Clc-like WD40 PF00400.32 KUM65220.1 - 4.5e-17 62.1 8.2 0.0019 19.0 0.3 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM65220.1 - 3.1e-08 33.8 0.9 0.0098 16.2 0.3 4.7 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KUM65220.1 - 4e-07 29.1 1.8 0.00012 20.9 0.3 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KUM65220.1 - 0.041 12.6 0.0 1.8 7.2 0.0 2.4 2 1 0 2 2 2 0 Nup133 N terminal like PsbP PF01789.16 KUM65220.1 - 0.11 12.6 0.1 0.27 11.4 0.1 1.6 1 0 0 1 1 1 0 PsbP DIE2_ALG10 PF04922.12 KUM65221.1 - 1.5e-125 419.6 0.0 2.3e-125 419.0 0.0 1.3 1 1 0 1 1 1 1 DIE2/ALG10 family Beta-lactamase PF00144.24 KUM65222.1 - 8.1e-41 140.3 0.2 1.1e-40 140.0 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase Fcf1 PF04900.12 KUM65223.1 - 1.5e-19 70.2 0.2 6.6e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 Fcf1 Tmemb_9 PF05434.11 KUM65223.1 - 0.13 12.2 0.3 0.67 9.8 0.0 2.2 2 1 0 2 2 2 0 TMEM9 PP2C PF00481.21 KUM65224.1 - 0.0017 18.1 0.1 0.19 11.4 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KUM65224.1 - 0.0027 17.6 0.0 0.013 15.4 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Cmc1 PF08583.10 KUM65225.1 - 2.9e-17 62.4 3.3 3.7e-17 62.1 3.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 KUM65225.1 - 0.045 14.0 0.4 10 6.5 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CUE PF02845.16 KUM65226.1 - 2.7e-10 39.8 0.0 4.8e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain HTH_32 PF13565.6 KUM65226.1 - 0.0063 17.1 0.2 0.7 10.5 0.0 2.2 2 0 0 2 2 2 2 Homeodomain-like domain G2BR PF18442.1 KUM65226.1 - 0.01 15.5 10.7 0.017 14.7 10.7 1.3 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) FAD_binding_3 PF01494.19 KUM65227.1 - 8.8e-14 51.5 2.4 5.9e-13 48.8 0.1 2.3 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KUM65227.1 - 0.0012 18.1 0.2 0.079 12.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM65227.1 - 0.0022 18.2 0.3 0.0056 16.9 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KUM65227.1 - 0.003 16.9 0.0 0.008 15.5 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase SE PF08491.10 KUM65227.1 - 0.012 14.7 0.0 0.068 12.2 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.6 KUM65227.1 - 0.061 13.3 0.7 7.8 6.5 0.0 2.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 KUM65227.1 - 0.069 12.7 3.4 1.1 8.8 1.3 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KUM65227.1 - 0.19 10.5 2.4 0.76 8.6 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase APP_amyloid PF10515.9 KUM65228.1 - 0.016 15.7 0.0 0.066 13.7 0.0 2.2 1 0 0 1 1 1 0 Beta-amyloid precursor protein C-terminus CdvA PF18822.1 KUM65228.1 - 0.29 10.9 1.4 8.1 6.3 0.0 3.1 4 0 0 4 4 4 0 CdvA-like coiled-coil domain AAA_11 PF13086.6 KUM65229.1 - 1.3e-63 215.3 0.2 2.4e-63 214.4 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KUM65229.1 - 1.6e-47 161.7 0.0 2.7e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KUM65229.1 - 1.2e-13 51.2 0.0 2.3e-12 47.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KUM65229.1 - 3.7e-09 37.1 0.0 8.7e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KUM65229.1 - 2.2e-06 27.2 0.2 5.4e-05 22.6 0.2 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KUM65229.1 - 7.6e-06 26.2 0.1 0.00014 22.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KUM65229.1 - 1.1e-05 25.5 0.0 5.7e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KUM65229.1 - 1.4e-05 25.0 0.0 0.027 14.2 0.0 2.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KUM65229.1 - 0.00015 21.7 0.0 0.081 12.8 0.0 2.3 2 0 0 2 2 2 2 Helicase PhoH PF02562.16 KUM65229.1 - 0.00018 21.0 0.0 0.098 12.1 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.21 KUM65229.1 - 0.00069 19.2 0.0 0.0017 17.9 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 KUM65229.1 - 0.00083 19.2 0.1 0.019 14.7 0.1 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KUM65229.1 - 0.0014 17.7 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KUM65229.1 - 0.0016 18.4 0.1 0.0076 16.2 0.0 2.0 2 0 0 2 2 2 1 Flavivirus DEAD domain PIF1 PF05970.14 KUM65229.1 - 0.003 16.8 0.0 2.4 7.2 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase AAA_24 PF13479.6 KUM65229.1 - 0.0035 17.1 0.0 0.0076 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KUM65229.1 - 0.0068 16.8 0.0 0.014 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KUM65229.1 - 0.022 14.7 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) HEM4 PF02602.15 KUM65229.1 - 0.033 13.5 0.1 0.47 9.8 0.0 2.2 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD IstB_IS21 PF01695.17 KUM65229.1 - 0.034 13.9 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 KUM65229.1 - 0.039 14.4 0.0 0.22 11.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 KUM65229.1 - 0.047 12.6 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain TK PF00265.18 KUM65229.1 - 0.097 12.5 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Thymidine kinase ERG4_ERG24 PF01222.17 KUM65230.1 - 2.5e-142 474.6 6.5 2.9e-142 474.5 6.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KUM65230.1 - 1.6e-05 24.5 0.1 5.1e-05 22.9 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ferlin_C PF16165.5 KUM65230.1 - 2.6 8.0 4.0 1.9 8.4 1.7 1.9 2 0 0 2 2 2 0 Ferlin C-terminus Acetyltransf_1 PF00583.25 KUM65231.1 - 4.2e-05 23.8 0.0 8.8e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KUM65231.1 - 0.00018 21.5 0.0 0.023 14.6 0.0 2.5 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KUM65231.1 - 0.0065 16.9 0.0 0.014 15.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Cupin_2 PF07883.11 KUM65232.1 - 3.6e-11 42.6 0.0 0.0001 21.9 0.0 2.5 3 0 0 3 3 3 2 Cupin domain Cupin_1 PF00190.22 KUM65232.1 - 0.071 12.7 0.2 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Cupin Lant_dehydr_N PF04738.13 KUM65232.1 - 0.17 10.0 0.0 0.23 9.5 0.0 1.2 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus Peptidase_S10 PF00450.22 KUM65234.1 - 1.1e-101 341.3 0.3 1.3e-101 341.0 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase HhH-GPD PF00730.25 KUM65235.1 - 1.2e-19 70.8 0.0 2.2e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KUM65235.1 - 3.8e-08 32.8 0.0 7.7e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF4611 PF15387.6 KUM65235.1 - 0.19 11.9 1.2 23 5.3 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) UQ_con PF00179.26 KUM65236.1 - 4.7e-37 126.8 0.0 5.2e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KUM65236.1 - 0.0076 16.5 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain UBX PF00789.20 KUM65237.1 - 2.3e-11 43.7 0.0 6.7e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.6 KUM65237.1 - 1.5e-10 40.7 0.0 3.5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain DUF1682 PF07946.14 KUM65237.1 - 0.56 9.3 5.6 1.1 8.4 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DDRGK PF09756.9 KUM65237.1 - 7 6.2 11.3 12 5.5 11.3 1.2 1 0 0 1 1 1 0 DDRGK domain Pro_isomerase PF00160.21 KUM65238.1 - 2.7e-44 151.2 0.7 3e-44 151.1 0.7 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EzrA PF06160.12 KUM65240.1 - 0.00011 20.5 13.5 0.00011 20.5 13.5 3.5 2 1 0 3 3 3 3 Septation ring formation regulator, EzrA Zw10 PF06248.13 KUM65240.1 - 0.00045 18.9 8.4 0.00045 18.9 8.4 2.4 2 1 1 3 3 3 1 Centromere/kinetochore Zw10 RTBV_P12 PF06361.11 KUM65240.1 - 0.0081 16.5 3.8 5.3 7.5 0.0 3.6 2 1 1 3 3 3 2 Rice tungro bacilliform virus P12 protein CENP-F_leu_zip PF10473.9 KUM65240.1 - 0.012 15.6 4.2 0.012 15.6 4.2 4.6 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran_CTD PF16326.5 KUM65240.1 - 0.017 15.3 3.4 0.017 15.3 3.4 6.6 2 2 5 8 8 8 0 ABC transporter C-terminal domain Fib_alpha PF08702.10 KUM65240.1 - 0.24 11.6 31.6 0.047 13.9 4.9 5.0 2 1 2 5 5 5 0 Fibrinogen alpha/beta chain family Osmo_CC PF08946.10 KUM65240.1 - 0.53 10.6 18.3 0.8 10.0 2.1 5.2 4 1 0 4 4 4 0 Osmosensory transporter coiled coil Baculo_p24 PF05073.12 KUM65240.1 - 9 6.0 18.2 0.099 12.4 1.2 3.1 3 0 0 3 3 3 0 Baculovirus P24 capsid protein RNA_pol_Rpb5_C PF01191.19 KUM65241.1 - 1.4e-33 114.5 0.1 2.2e-33 113.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KUM65241.1 - 1.2e-23 83.4 0.0 1.8e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KUM65241.1 - 0.015 15.3 0.0 0.036 14.1 0.0 1.6 2 0 0 2 2 2 0 Restriction endonuclease BetaGal_dom2 PF10435.9 KUM65242.1 - 1e-61 207.9 2.7 1e-61 207.9 2.7 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KUM65242.1 - 5.9e-54 181.5 8.3 2.3e-31 108.7 0.5 2.5 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain Glyco_hydro_35 PF01301.19 KUM65242.1 - 1.4e-43 149.8 0.0 2e-43 149.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom3 PF13363.6 KUM65242.1 - 2.2e-24 84.8 0.2 4.4e-24 83.9 0.2 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 DUF3060 PF11259.8 KUM65242.1 - 0.37 10.5 2.1 4.6 7.0 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3060) Spem1 PF15670.5 KUM65243.1 - 0.2 11.2 0.8 0.37 10.3 0.8 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 Methyltr_RsmB-F PF01189.17 KUM65244.1 - 1.4e-32 113.0 0.0 1.7e-25 89.9 0.0 3.1 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Glyco_hydro_35 PF01301.19 KUM65245.1 - 2.8e-49 168.5 0.0 3.6e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Cellulase PF00150.18 KUM65245.1 - 0.073 12.5 0.0 0.081 12.3 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Peptidase_M16 PF00675.20 KUM65246.1 - 4.1e-56 189.1 0.2 1.1e-55 187.7 0.2 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KUM65246.1 - 9.9e-41 139.8 0.0 1.9e-38 132.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain DUF4882 PF16223.5 KUM65247.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4882) Epimerase PF01370.21 KUM65249.1 - 8.8e-20 71.2 0.0 1.2e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM65249.1 - 1.9e-12 47.2 0.0 4.1e-12 46.2 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KUM65249.1 - 4.8e-12 45.5 0.0 6.4e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KUM65249.1 - 2.1e-06 27.1 0.0 2.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KUM65249.1 - 0.00084 18.6 0.0 0.093 11.9 0.0 2.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KUM65249.1 - 0.00084 19.3 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KUM65249.1 - 0.0013 18.2 0.0 0.0034 16.9 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KUM65249.1 - 0.0024 18.1 0.0 0.0039 17.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KUM65249.1 - 0.0027 16.9 0.0 0.0068 15.6 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 KUM65249.1 - 0.0034 17.5 0.0 0.013 15.6 0.0 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 KUM65249.1 - 0.0057 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 KUM65249.1 - 0.024 15.1 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_L22 PF00237.19 KUM65251.1 - 6.8e-40 135.5 0.1 4e-39 133.0 0.0 2.1 1 1 1 2 2 2 1 Ribosomal protein L22p/L17e 2-Hacid_dh_C PF02826.19 KUM65252.1 - 3.9e-52 176.2 0.0 5.4e-52 175.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KUM65252.1 - 1.1e-19 70.4 0.0 1.3e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KUM65252.1 - 0.0025 18.0 0.5 0.0056 16.9 0.2 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.12 KUM65253.1 - 4.6e-29 100.5 1.2 1.1e-28 99.2 0.9 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KUM65253.1 - 4.1e-13 49.3 0.4 9.6e-06 25.2 0.0 2.3 1 1 1 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 KUM65253.1 - 3e-11 43.4 0.3 8.4e-11 42.0 0.3 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KUM65253.1 - 0.00011 22.5 0.1 0.00025 21.3 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KUM65253.1 - 0.035 13.8 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short_C2 PF13561.6 KUM65254.1 - 1.7e-44 152.2 0.3 1.9e-44 152.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM65254.1 - 1.1e-42 145.7 0.2 1.5e-42 145.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM65254.1 - 2.6e-11 43.8 0.2 3.7e-11 43.3 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KUM65254.1 - 1.1e-05 25.5 0.0 3.1e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KUM65254.1 - 2.7e-05 23.7 0.2 8e-05 22.2 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM65254.1 - 0.00015 21.3 0.1 0.00024 20.6 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KUM65254.1 - 0.00026 20.2 0.0 0.00032 19.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KUM65254.1 - 0.0085 16.3 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Gtr1_RagA PF04670.12 KUM65254.1 - 0.18 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Fungal_trans PF04082.18 KUM65255.1 - 2e-11 43.4 0.0 5.8e-10 38.6 0.0 2.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM65255.1 - 1e-05 25.6 10.4 1.8e-05 24.8 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KUM65256.1 - 3.1e-18 65.9 0.0 3.7e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM65256.1 - 9.5e-12 45.0 0.0 1.2e-11 44.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM65256.1 - 1.6e-08 34.7 0.0 1.9e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM65256.1 - 0.00011 21.8 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KUM65256.1 - 0.0021 17.4 0.1 0.0034 16.7 0.1 1.2 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 KUM65256.1 - 0.017 14.6 0.0 0.019 14.4 0.0 1.0 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KUM65256.1 - 0.03 13.4 0.0 0.054 12.6 0.0 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 KUM65256.1 - 0.14 11.5 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 KUM65257.1 - 3.7e-32 111.8 0.1 4.4e-32 111.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM65257.1 - 2e-20 73.1 0.1 3.3e-20 72.4 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase Ferric_reduct PF01794.19 KUM65258.1 - 2.8e-24 85.6 7.3 7.3e-24 84.3 7.3 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KUM65258.1 - 2.4e-12 47.2 0.0 1.3e-07 31.9 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KUM65258.1 - 4.4e-11 42.8 0.1 3.2e-06 27.2 0.1 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KUM65258.1 - 0.042 14.5 0.0 0.21 12.2 0.0 2.2 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain ABC2_membrane PF01061.24 KUM65259.1 - 1.6e-86 289.1 50.0 5.8e-49 166.4 21.0 3.3 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 KUM65259.1 - 2.7e-39 134.8 0.4 2.1e-18 67.1 0.0 3.6 4 0 0 4 4 4 2 ABC transporter PDR_CDR PF06422.12 KUM65259.1 - 3.9e-37 126.1 2.9 2.4e-34 117.1 0.2 3.7 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KUM65259.1 - 4.3e-19 68.9 0.3 1.2e-18 67.4 0.3 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KUM65259.1 - 1.8e-07 31.2 0.5 8.3e-05 22.6 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KUM65259.1 - 1.7e-05 25.3 2.1 0.0047 17.3 0.1 2.7 3 0 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.6 KUM65259.1 - 8.6e-05 22.2 0.1 0.00065 19.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KUM65259.1 - 0.00048 19.8 2.2 0.028 14.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KUM65259.1 - 0.00062 19.9 2.2 0.026 14.7 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KUM65259.1 - 0.00083 19.9 0.0 0.026 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KUM65259.1 - 0.0015 17.7 16.6 0.0015 17.7 16.6 3.0 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 KUM65259.1 - 0.0022 17.9 0.0 2.9 7.6 0.1 2.8 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KUM65259.1 - 0.0045 16.5 0.0 0.45 9.9 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KUM65259.1 - 0.008 16.5 0.8 1.2 9.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KUM65259.1 - 0.024 15.0 0.1 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KUM65259.1 - 0.027 14.2 0.3 2.9 7.6 0.0 2.6 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA PF00004.29 KUM65259.1 - 0.055 13.9 0.1 17 5.8 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KUM65259.1 - 0.059 13.3 4.4 3.8 7.4 0.2 3.3 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.6 KUM65259.1 - 0.06 13.1 1.8 3.9 7.2 0.3 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KUM65259.1 - 0.061 12.9 0.5 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KUM65259.1 - 0.088 13.2 0.0 28 5.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 KUM65259.1 - 0.09 12.9 0.1 18 5.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Corona_6B_7B PF03262.13 KUM65259.1 - 0.11 11.9 0.4 0.44 10.0 0.1 2.0 2 0 0 2 2 2 0 Coronavirus 6B/7B protein AAA_23 PF13476.6 KUM65259.1 - 0.13 12.7 0.6 3.4 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KUM65259.1 - 0.15 11.8 0.1 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase LPMO_10 PF03067.15 KUM65260.1 - 1.4e-13 52.0 0.4 2.2e-13 51.3 0.4 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading APH PF01636.23 KUM65261.1 - 8.6e-13 48.8 0.0 1.8e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KUM65261.1 - 3.4e-05 23.5 0.0 6.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KUM65261.1 - 5.3e-05 22.7 0.0 0.00043 19.7 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain CRAL_TRIO PF00650.20 KUM65261.1 - 0.022 14.5 0.0 0.048 13.4 0.0 1.6 1 1 0 1 1 1 0 CRAL/TRIO domain Arylsulfotran_2 PF14269.6 KUM65262.1 - 6.8e-60 203.0 6.6 9.9e-60 202.4 6.6 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KUM65262.1 - 4.7e-21 75.1 5.7 3.5e-19 69.0 5.6 2.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) CybS PF05328.12 KUM65262.1 - 0.048 13.3 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit HAD_2 PF13419.6 KUM65264.1 - 1.2e-10 41.8 0.0 7e-10 39.3 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KUM65264.1 - 0.00024 21.4 0.0 0.016 15.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase EcoEI_R_C PF08463.10 KUM65264.1 - 0.028 14.6 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 EcoEI R protein C-terminal T3SS_needle_reg PF09025.10 KUM65264.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 YopR, type III needle-polymerisation regulator GAT PF03127.14 KUM65265.1 - 2.6e-16 59.7 0.0 6.5e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 GAT domain VHS PF00790.19 KUM65265.1 - 2.6e-05 24.1 0.0 0.00015 21.6 0.0 2.2 3 0 0 3 3 3 1 VHS domain DUF4656 PF15551.6 KUM65265.1 - 0.062 12.8 0.3 0.099 12.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4656) ADH_zinc_N_2 PF13602.6 KUM65267.1 - 9.2e-23 81.8 0.0 1.5e-22 81.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KUM65267.1 - 2.7e-17 62.9 0.1 3.9e-17 62.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KUM65267.1 - 0.041 13.3 1.1 0.1 12.0 1.1 1.7 1 1 0 1 1 1 0 short chain dehydrogenase DFP PF04127.15 KUM65267.1 - 0.088 12.6 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Methyltransf_25 PF13649.6 KUM65268.1 - 1.4e-13 51.3 0.0 2.8e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM65268.1 - 3.5e-12 46.8 0.0 6.6e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM65268.1 - 6.1e-11 42.3 0.0 9e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM65268.1 - 3.9e-09 37.1 0.0 8.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM65268.1 - 2e-07 31.0 0.0 2.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KUM65268.1 - 1.8e-05 24.4 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 KUM65268.1 - 0.013 15.0 0.0 0.32 10.4 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain TehB PF03848.14 KUM65268.1 - 0.029 13.8 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 KUM65268.1 - 0.095 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 KUM65268.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 KUM65268.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KUM65268.1 - 0.18 11.1 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CYSTM PF12734.7 KUM65269.1 - 0.99 9.8 79.5 1.8e+04 -5.6 63.3 5.9 1 1 1 2 2 2 0 Cysteine-rich TM module stress tolerance MFS_1 PF07690.16 KUM65270.1 - 3e-30 105.4 42.9 3.9e-20 72.1 15.9 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily D123 PF07065.14 KUM65270.1 - 0.015 14.5 0.0 3.3 6.8 0.1 2.1 2 0 0 2 2 2 0 D123 bZIP_1 PF00170.21 KUM65271.1 - 4.3e-07 29.9 2.6 8.1e-07 29.0 2.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor ABC_tran PF00005.27 KUM65273.1 - 4.7e-17 62.8 0.0 8.1e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KUM65273.1 - 0.00013 21.9 0.0 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Rad17 PF03215.15 KUM65273.1 - 0.0059 16.5 0.0 0.017 15.0 0.0 1.8 1 1 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 KUM65273.1 - 0.013 15.9 0.0 0.02 15.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KUM65273.1 - 0.08 13.4 0.1 0.26 11.7 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KUM65273.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea FAM216B PF15107.6 KUM65273.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 FAM216B protein family Ribosomal_S28e PF01200.18 KUM65273.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S28e ABC2_membrane PF01061.24 KUM65274.1 - 5.7e-09 35.7 11.6 0.00033 20.1 0.3 2.0 2 0 0 2 2 2 2 ABC-2 type transporter SPC12 PF06645.13 KUM65274.1 - 0.82 9.8 6.8 0.5 10.5 4.0 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Tam41_Mmp37 PF09139.11 KUM65276.1 - 1.2e-129 432.4 0.0 1.4e-129 432.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Aminotran_1_2 PF00155.21 KUM65277.1 - 9.2e-62 209.3 0.0 1.1e-61 209.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KUM65277.1 - 0.08 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Allinase DUF1115 PF06544.12 KUM65278.1 - 1.3e-11 44.8 0.0 2.1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) CASP_C PF08172.12 KUM65280.1 - 1.3e-89 299.8 2.4 1.3e-89 299.8 2.4 3.2 2 1 2 4 4 4 1 CASP C terminal ZapB PF06005.12 KUM65280.1 - 0.062 13.8 0.4 0.062 13.8 0.4 6.5 6 1 0 6 6 6 0 Cell division protein ZapB SlyX PF04102.12 KUM65280.1 - 2.6 8.7 0.0 2.6 8.7 0.0 5.9 6 0 0 6 6 6 0 SlyX Lectin_N PF03954.14 KUM65280.1 - 4.4 7.0 14.1 0.63 9.8 0.0 4.5 3 1 1 4 4 4 0 Hepatic lectin, N-terminal domain GNT-I PF03071.15 KUM65280.1 - 5.8 5.6 6.4 0.42 9.3 0.1 2.2 2 0 0 2 2 2 0 GNT-I family Vps39_2 PF10367.9 KUM65281.1 - 4.1e-06 27.2 0.0 1.4e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KUM65281.1 - 0.0053 17.0 0.0 0.018 15.3 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Fibrillarin PF01269.17 KUM65282.1 - 2.1e-103 344.3 0.0 2.6e-103 344.0 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KUM65282.1 - 4.1e-06 26.6 0.0 7.1e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KUM65282.1 - 0.014 15.2 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3455 PF11937.8 KUM65283.1 - 6e-48 163.2 0.1 7.5e-48 162.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 KUM65283.1 - 1.5e-30 105.1 0.2 1.5e-30 105.1 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2990) Dioxygenase_C PF00775.21 KUM65284.1 - 3.3e-38 130.9 0.0 4.7e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KUM65284.1 - 2e-32 110.9 0.0 3.5e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Fasciclin PF02469.22 KUM65285.1 - 6.1e-43 146.1 0.0 8.8e-25 87.4 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain LSM PF01423.22 KUM65286.1 - 2.7e-22 78.2 0.9 3.3e-22 77.9 0.9 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 KUM65286.1 - 0.0025 18.3 7.1 0.0041 17.6 7.1 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 DUF150_C PF17384.2 KUM65286.1 - 0.014 15.6 0.1 0.021 14.9 0.1 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain SM-ATX PF14438.6 KUM65286.1 - 0.035 14.2 0.1 0.045 13.9 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Zn_clus PF00172.18 KUM65287.1 - 0.061 13.5 9.9 0.15 12.2 9.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pan3_PK PF18101.1 KUM65288.1 - 2.9e-61 205.5 0.1 4.4e-61 204.9 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KUM65288.1 - 2.7e-06 27.0 0.0 4.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM65288.1 - 0.023 14.0 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Cation_efflux PF01545.21 KUM65289.1 - 7.8e-15 55.1 7.1 9.9e-15 54.8 7.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KUM65289.1 - 5.3e-10 39.3 0.3 1.4e-09 37.9 0.3 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Adaptin_binding PF10199.9 KUM65289.1 - 2.6 8.7 5.6 14 6.3 5.6 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 zf-C2H2_jaz PF12171.8 KUM65290.1 - 4.1e-08 33.3 0.7 6.8e-08 32.6 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KUM65290.1 - 2.3e-05 24.6 0.9 3.8e-05 23.9 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KUM65290.1 - 0.0074 16.7 0.6 0.013 15.9 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KUM65290.1 - 0.1 13.0 0.5 0.43 11.0 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 KUM65290.1 - 0.14 12.3 0.9 0.24 11.5 0.9 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger DUF3340 PF11818.8 KUM65290.1 - 0.35 11.0 18.1 0.29 11.3 9.2 2.1 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) DUF123 PF01986.16 KUM65290.1 - 0.46 11.0 2.6 1.6 9.3 2.6 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF123 BIR PF00653.21 KUM65291.1 - 1.2e-46 157.2 5.6 7.5e-23 81.0 0.1 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain AMP-binding PF00501.28 KUM65292.1 - 8.2e-37 126.8 0.0 1.4e-36 126.1 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.25 KUM65292.1 - 4.9e-12 46.0 0.1 9.8e-12 45.1 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 KUM65292.1 - 0.0021 16.8 0.0 0.0034 16.1 0.0 1.3 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 KUM65292.1 - 0.07 14.1 0.0 0.19 12.7 0.0 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Cypo_polyhedrin PF05865.11 KUM65292.1 - 0.16 11.3 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 Cypovirus polyhedrin protein Pyrid_ox_like PF16242.5 KUM65293.1 - 2.6e-21 75.8 0.0 4e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KUM65293.1 - 2.2e-07 31.0 0.0 3.8e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 KUM65293.1 - 0.049 13.3 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative FMN-binding domain Methyltransf_2 PF00891.18 KUM65294.1 - 3.4e-15 55.9 0.0 4.7e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MarR_2 PF12802.7 KUM65294.1 - 0.00024 20.9 0.0 0.00048 20.0 0.0 1.5 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 KUM65294.1 - 0.0052 17.1 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator Dimerisation2 PF16864.5 KUM65294.1 - 0.021 14.8 0.0 0.074 13.0 0.0 1.8 2 0 0 2 2 2 0 Dimerisation domain HTH_Crp_2 PF13545.6 KUM65294.1 - 0.033 14.2 0.0 0.095 12.7 0.0 1.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_AraC PF00165.23 KUM65294.1 - 0.046 13.8 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family MarR PF01047.22 KUM65294.1 - 0.081 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 MarR family AMP-binding PF00501.28 KUM65295.1 - 1.4e-17 63.5 0.0 1.6e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme TFIID-18kDa PF02269.16 KUM65297.1 - 1.6e-28 98.5 0.2 1.4e-27 95.5 0.1 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 KUM65297.1 - 0.017 15.2 0.1 0.048 13.8 0.0 1.9 2 0 0 2 2 2 0 hTAFII28-like protein conserved region MFS_1 PF07690.16 KUM65298.1 - 4.2e-15 55.5 34.1 4.2e-15 55.5 34.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TP_methylase PF00590.20 KUM65299.1 - 5.9e-23 81.9 0.4 1.1e-22 81.1 0.4 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Cyclase PF04199.13 KUM65300.1 - 9.1e-16 58.3 0.0 1.3e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase adh_short_C2 PF13561.6 KUM65301.1 - 3.1e-60 203.6 0.5 3.6e-60 203.4 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM65301.1 - 5.4e-42 143.5 0.6 6.9e-42 143.1 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM65301.1 - 1.7e-12 47.6 0.1 4e-12 46.4 0.3 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 KUM65302.1 - 5.9e-53 179.8 0.0 7.3e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM65302.1 - 8.9e-42 142.8 0.0 1.2e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM65302.1 - 5.1e-14 52.6 0.0 6.8e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KUM65302.1 - 0.0024 17.3 0.0 0.5 9.7 0.0 2.0 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KUM65302.1 - 0.0043 16.6 0.0 0.023 14.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glu_dehyd_C PF16912.5 KUM65302.1 - 0.062 12.8 0.0 0.15 11.6 0.0 1.4 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus 3Beta_HSD PF01073.19 KUM65302.1 - 0.069 12.1 0.0 0.11 11.5 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KUM65302.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pectate_lyase_3 PF12708.7 KUM65303.1 - 7.2e-98 326.7 23.5 3e-83 278.9 10.2 3.3 3 1 1 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KUM65303.1 - 3.3e-09 36.3 2.9 0.00021 20.9 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Abhydrolase_2 PF02230.16 KUM65304.1 - 6.3e-05 22.9 0.0 9.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 KUM65304.1 - 0.0014 18.1 0.7 0.0053 16.3 0.0 1.9 2 0 0 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.20 KUM65304.1 - 0.0019 17.9 0.1 0.0039 16.9 0.1 1.6 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KUM65304.1 - 0.023 14.2 0.0 0.24 10.9 0.1 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family CRAL_TRIO PF00650.20 KUM65305.1 - 3.5e-43 147.1 0.0 6.6e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KUM65305.1 - 2.8e-14 53.0 2.0 5e-14 52.2 0.3 2.3 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KUM65305.1 - 3e-06 27.4 0.0 5.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Skp1 PF01466.19 KUM65305.1 - 0.028 14.6 4.5 0.061 13.5 0.3 2.8 3 0 0 3 3 3 0 Skp1 family, dimerisation domain Pkinase PF00069.25 KUM65307.1 - 6.4e-69 232.2 0.0 7.6e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM65307.1 - 2.9e-32 112.0 0.0 4e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KUM65307.1 - 0.00016 21.1 0.2 0.00025 20.5 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KUM65307.1 - 0.004 16.1 0.1 0.0063 15.5 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KUM65307.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KUM65307.1 - 0.031 14.2 0.3 0.094 12.6 0.3 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KUM65307.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DASH_Dam1 PF08653.10 KUM65308.1 - 2.6e-29 100.8 2.3 3.8e-29 100.3 2.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 UCH PF00443.29 KUM65309.1 - 1.4e-45 155.8 1.4 1.8e-45 155.5 1.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KUM65309.1 - 3.2e-15 56.5 4.9 2.7e-14 53.5 4.9 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KUM65309.1 - 0.0059 16.9 1.7 0.0059 16.9 1.7 3.3 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 KUM65309.1 - 5 6.5 9.4 0.66 9.4 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase HIT PF01230.23 KUM65310.1 - 2.5e-20 73.0 0.2 3.4e-20 72.6 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KUM65310.1 - 1.8e-12 47.8 0.0 2.7e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KUM65310.1 - 0.00018 21.4 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Fringe PF02434.16 KUM65311.1 - 2.5e-06 27.1 2.9 2.2e-05 24.0 0.6 2.7 2 1 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 KUM65311.1 - 0.05 13.4 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 Galactosyltransferase NmrA PF05368.13 KUM65312.1 - 4.4e-17 62.4 0.0 5.6e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KUM65312.1 - 5.1e-15 55.6 0.1 1.4e-14 54.1 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KUM65312.1 - 3.6e-14 53.1 0.0 5.1e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KUM65312.1 - 8.3e-11 41.4 0.1 1.7e-10 40.4 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KUM65312.1 - 5.3e-08 32.6 0.2 3.9e-07 29.8 0.1 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KUM65312.1 - 1.3e-07 31.0 0.0 1.5e-06 27.5 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KUM65312.1 - 1.5e-05 24.3 0.5 0.014 14.6 0.0 2.7 1 1 1 3 3 3 2 Male sterility protein adh_short PF00106.25 KUM65312.1 - 9.9e-05 21.9 0.0 0.00018 21.1 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM65312.1 - 0.0027 17.3 0.0 0.0044 16.6 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KUM65312.1 - 0.005 16.0 0.0 0.007 15.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KUM65312.1 - 0.052 13.4 0.0 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 KR domain DUF4838 PF16126.5 KUM65312.1 - 0.056 12.8 0.1 5.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4838) HEM4 PF02602.15 KUM65313.1 - 3.1e-40 138.0 0.0 3.6e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Glyco_trans_2_3 PF13632.6 KUM65314.1 - 2.1e-10 40.9 0.8 2.1e-10 40.9 0.8 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KUM65314.1 - 2.3e-05 24.4 0.1 7.3e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KUM65314.1 - 5e-05 22.8 0.1 0.00024 20.6 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 KUM65314.1 - 0.065 11.9 0.1 0.78 8.3 0.1 2.2 1 1 0 1 1 1 0 Chitin synthase ATP-synt_C PF00137.21 KUM65314.1 - 0.27 11.6 4.3 2.2 8.7 1.3 2.7 2 0 0 2 2 2 0 ATP synthase subunit C Ank_2 PF12796.7 KUM65315.1 - 7.3e-47 157.9 37.0 7.8e-11 42.4 0.1 5.6 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM65315.1 - 4.9e-37 125.8 7.7 5.1e-07 30.1 0.1 8.2 4 3 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM65315.1 - 4.4e-31 106.5 13.6 7e-05 23.0 0.1 8.9 6 2 2 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KUM65315.1 - 1.3e-26 91.8 28.5 0.002 18.5 0.2 10.9 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.6 KUM65315.1 - 3e-24 82.4 14.9 0.15 12.7 0.1 10.8 12 0 0 12 12 9 8 Ankyrin repeat NACHT PF05729.12 KUM65315.1 - 2.1e-09 37.5 0.0 4.5e-08 33.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KUM65315.1 - 1.4e-08 35.3 0.2 8e-08 32.8 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KUM65315.1 - 0.0078 16.5 0.0 0.027 14.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KUM65315.1 - 0.046 14.3 0.0 0.15 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KUM65315.1 - 0.064 13.8 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Ses_B PF17046.5 KUM65315.1 - 0.066 13.2 2.7 0.12 12.3 2.7 1.4 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein Ploopntkinase3 PF18751.1 KUM65315.1 - 0.091 12.7 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_29 PF13555.6 KUM65315.1 - 0.12 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zn_ribbon_17 PF17120.5 KUM65315.1 - 7.5 6.3 9.6 3.7 7.2 6.4 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Glyco_hydro_15 PF00723.21 KUM65316.1 - 2.4e-107 359.5 0.2 2.7e-107 359.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Ank_2 PF12796.7 KUM65317.1 - 1.2e-82 272.5 11.4 1.2e-10 41.9 0.1 12.6 7 4 4 12 12 12 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM65317.1 - 2.9e-55 183.9 23.3 2.7e-10 40.6 0.1 15.3 11 5 5 16 16 16 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM65317.1 - 5.2e-47 152.4 31.1 2e-05 24.6 0.0 21.4 24 0 0 24 24 23 9 Ankyrin repeat Ank_5 PF13857.6 KUM65317.1 - 1.8e-46 155.6 19.9 1.5e-07 31.5 0.0 17.0 14 3 4 19 19 18 11 Ankyrin repeats (many copies) Ank PF00023.30 KUM65317.1 - 1.9e-44 148.2 31.4 1.7e-06 28.2 0.2 18.9 20 0 0 20 20 19 9 Ankyrin repeat NACHT PF05729.12 KUM65317.1 - 1.3e-06 28.5 0.6 7.4e-06 26.0 0.1 2.6 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 KUM65317.1 - 0.002 18.5 0.0 0.008 16.6 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain Helo_like_N PF17111.5 KUM65317.1 - 0.0031 16.9 0.2 0.008 15.6 0.2 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NB-ARC PF00931.22 KUM65317.1 - 0.0041 16.3 0.2 0.0077 15.4 0.2 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KUM65317.1 - 0.037 14.3 0.0 0.15 12.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain Phage_TAC_11 PF11836.8 KUM65317.1 - 0.12 12.5 0.0 18 5.5 0.0 3.3 3 0 0 3 3 3 0 Phage tail tube protein, GTA-gp10 Ribonuclease_3 PF00636.26 KUM65318.1 - 6.2e-08 33.2 0.0 1.2e-07 32.2 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KUM65318.1 - 6e-06 26.4 0.0 7.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like FMO-like PF00743.19 KUM65319.1 - 8.5e-30 103.7 0.0 1e-15 57.2 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KUM65319.1 - 4.5e-12 45.8 2.5 5.3e-10 39.0 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM65319.1 - 4e-09 36.1 0.0 7e-08 32.0 0.1 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM65319.1 - 7.2e-09 35.2 0.5 1e-06 28.1 0.0 2.8 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KUM65319.1 - 3.2e-05 24.0 1.7 0.013 15.4 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KUM65319.1 - 0.00024 21.2 0.1 0.0011 19.2 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM65319.1 - 0.023 14.3 1.0 1.3 8.5 0.4 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase Semialdhyde_dh PF01118.24 KUM65319.1 - 0.035 14.5 0.0 0.87 10.0 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KUM65319.1 - 0.065 13.3 0.1 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KUM65319.1 - 0.094 11.9 0.9 0.15 11.3 0.2 1.6 2 0 0 2 2 2 0 Thi4 family UPF0149 PF03695.13 KUM65319.1 - 0.11 12.8 0.2 0.18 12.1 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) MFS_1 PF07690.16 KUM65320.1 - 1.4e-26 93.2 24.0 1.8e-26 93.0 24.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1772 PF08592.11 KUM65320.1 - 0.63 10.4 9.3 0.039 14.3 2.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) CN_hydrolase PF00795.22 KUM65321.1 - 9.8e-59 198.8 0.0 1.2e-58 198.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_L31e PF01198.19 KUM65321.1 - 5.2e-39 132.4 0.9 8.5e-39 131.7 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.18 KUM65321.1 - 0.14 11.7 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel DLH PF01738.18 KUM65322.1 - 5.3e-33 114.4 0.1 6e-33 114.2 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KUM65322.1 - 0.017 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ytp1 PF10355.9 KUM65323.1 - 5.3e-115 383.4 9.0 6.9e-115 383.0 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KUM65323.1 - 2.5e-19 69.0 7.6 3.9e-17 61.9 1.4 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) Zn_clus PF00172.18 KUM65324.1 - 0.00013 22.0 8.1 0.00025 21.1 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ran_BP1 PF00638.18 KUM65325.1 - 2.9e-09 37.3 0.0 5.7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 KUM65325.1 - 3.1e-05 24.6 1.3 3.1e-05 24.6 1.3 8.9 10 2 0 10 10 10 1 NUP50 (Nucleoporin 50 kDa) Hormone_3 PF00159.18 KUM65325.1 - 0.15 12.2 1.2 25 5.0 0.1 3.4 2 0 0 2 2 2 0 Pancreatic hormone peptide Plasmodium_Vir PF05795.11 KUM65326.1 - 0.25 10.7 0.5 0.32 10.4 0.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Gaa1 PF04114.14 KUM65327.1 - 2.9e-187 623.6 3.2 3.6e-187 623.3 3.2 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.22 KUM65328.1 - 3.3e-16 59.6 8.3 3.3e-16 59.6 8.3 1.5 2 0 0 2 2 2 1 Rhomboid family PCI PF01399.27 KUM65329.1 - 6.8e-10 39.4 0.0 1.4e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KUM65329.1 - 7.2e-05 22.3 0.5 0.00015 21.3 0.5 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix Chitin_bind_1 PF00187.19 KUM65330.1 - 0.021 15.3 9.7 0.18 12.3 9.7 2.6 1 1 0 1 1 1 0 Chitin recognition protein MGC-24 PF05283.11 KUM65330.1 - 7.1 7.1 13.5 23 5.4 13.5 1.9 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin UBA_4 PF14555.6 KUM65332.1 - 0.00019 21.2 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Sec23_trunk PF04811.15 KUM65334.1 - 1.6e-72 244.0 0.0 3e-72 243.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KUM65334.1 - 9.4e-24 83.2 0.3 4.7e-23 81.0 0.0 2.4 3 0 0 3 3 3 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KUM65334.1 - 4.8e-17 62.5 0.0 1.1e-16 61.3 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KUM65334.1 - 1.5e-16 60.2 4.7 2.5e-16 59.4 4.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KUM65334.1 - 2.1e-10 40.4 0.0 4.1e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KUM65334.1 - 0.018 14.4 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Kinesin PF00225.23 KUM65336.1 - 4.8e-81 272.3 3.1 6.5e-81 271.8 0.8 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KUM65336.1 - 9.3e-22 77.6 0.0 2.4e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding HHH PF00633.23 KUM65336.1 - 9.6e-06 25.2 0.1 0.16 11.9 0.0 3.2 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_5 PF14520.6 KUM65336.1 - 0.0013 19.3 0.0 2.9 8.5 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH_3 PF12836.7 KUM65336.1 - 0.036 14.3 0.1 7.6 6.9 0.0 3.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif DDHD PF02862.17 KUM65336.1 - 0.67 10.1 2.8 0.62 10.2 0.4 2.1 2 0 0 2 2 2 0 DDHD domain adh_short PF00106.25 KUM65337.1 - 1.8e-21 76.5 0.0 1.7e-20 73.3 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM65337.1 - 2.5e-14 53.4 0.0 2.2e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM65337.1 - 0.00012 22.0 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 KUM65338.1 - 1.2e-35 123.1 70.0 9.4e-26 90.6 36.9 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM65338.1 - 5e-06 25.6 31.4 0.00067 18.6 12.1 3.2 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 KUM65338.1 - 0.017 14.0 25.9 0.021 13.7 2.2 2.6 2 2 1 3 3 3 0 MFS_1 like family AIM24 PF01987.17 KUM65339.1 - 9.2e-47 159.4 0.0 1.2e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 SLS PF14611.6 KUM65339.1 - 0.016 15.0 2.1 0.12 12.2 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator PQQ_2 PF13360.6 KUM65339.1 - 0.031 13.8 0.2 0.052 13.1 0.2 1.4 1 0 0 1 1 1 0 PQQ-like domain ABC_membrane PF00664.23 KUM65340.1 - 1.9e-39 136.0 13.4 2.6e-39 135.5 13.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KUM65340.1 - 1.2e-33 116.6 0.0 2.3e-33 115.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KUM65340.1 - 2.3e-05 24.0 0.0 0.027 13.9 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KUM65340.1 - 0.00018 21.9 0.0 0.00041 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KUM65340.1 - 0.00068 19.9 0.0 0.0038 17.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KUM65340.1 - 0.0021 17.9 0.1 0.0087 15.9 0.0 2.0 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KUM65340.1 - 0.0099 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KUM65340.1 - 0.011 16.2 0.0 0.03 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 KUM65340.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.6 KUM65340.1 - 0.019 14.7 0.1 0.054 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 KUM65340.1 - 0.022 14.7 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 KUM65340.1 - 0.024 14.7 0.0 0.4 10.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KUM65340.1 - 0.045 13.7 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 KUM65340.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KUM65340.1 - 0.064 13.2 0.0 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KUM65340.1 - 0.07 13.6 0.0 0.38 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KUM65340.1 - 0.084 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KUM65340.1 - 0.11 12.7 0.0 0.34 11.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 KUM65340.1 - 0.14 11.9 0.5 17 5.1 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.6 KUM65340.1 - 0.58 10.4 2.2 5.7 7.2 0.6 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Cyto_heme_lyase PF01265.17 KUM65341.1 - 7.5e-40 137.3 4.5 1.9e-34 119.6 0.4 3.1 2 1 0 2 2 2 2 Cytochrome c/c1 heme lyase MDD_C PF18376.1 KUM65342.1 - 3.8e-66 222.4 0.0 5.4e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KUM65342.1 - 2.1e-09 37.5 0.5 5.3e-09 36.2 0.5 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Ndc1_Nup PF09531.10 KUM65343.1 - 1.1e-192 642.0 2.6 1.2e-192 641.9 2.6 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.6 KUM65344.1 - 5.6e-26 90.9 8.3 7.9e-26 90.4 2.7 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KUM65344.1 - 5.8e-12 45.4 2.0 5.8e-12 45.4 2.0 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KUM65344.1 - 1.2e-05 25.1 13.5 5.4e-05 22.9 12.9 2.2 1 1 1 2 2 2 1 Syntaxin Synaptobrevin PF00957.21 KUM65344.1 - 0.0029 17.4 0.6 0.011 15.5 0.6 2.0 1 0 0 1 1 1 1 Synaptobrevin Nre_C PF04895.12 KUM65344.1 - 0.032 14.1 1.2 0.076 12.9 0.1 2.2 3 0 0 3 3 3 0 Archaeal Nre, C-terminal DUF883 PF05957.13 KUM65344.1 - 0.15 12.6 0.1 0.15 12.6 0.1 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.11 KUM65344.1 - 0.33 8.9 6.8 0.72 7.7 6.8 1.6 1 1 0 1 1 1 0 Prominin T3SSipB PF16535.5 KUM65344.1 - 0.44 11.0 6.3 2.2 8.7 3.1 2.7 3 0 0 3 3 3 0 Type III cell invasion protein SipB DUF1664 PF07889.12 KUM65344.1 - 1.2 9.2 5.5 16 5.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.12 KUM65344.1 - 2.2 9.0 13.8 1.8 9.3 0.2 4.1 2 2 2 4 4 4 0 SlyX DUF5345 PF17280.2 KUM65344.1 - 2.7 8.0 6.1 1.8 8.6 0.1 3.0 3 1 0 3 3 3 0 Family of unknown function (DUF5345) LPP PF04728.13 KUM65344.1 - 3.3 8.2 6.2 7 7.1 0.1 3.6 3 1 0 3 3 3 0 Lipoprotein leucine-zipper YgaB PF14182.6 KUM65344.1 - 7.5 7.0 10.6 1.9 8.9 3.3 2.8 2 1 1 3 3 3 0 YgaB-like protein rRNA_proc-arch PF13234.6 KUM65345.1 - 9.7e-89 297.9 0.3 9.7e-89 297.9 0.3 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 KUM65345.1 - 3e-55 186.4 2.9 7.9e-55 185.0 2.9 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KUM65345.1 - 3.5e-18 66.0 0.2 1.3e-17 64.1 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM65345.1 - 1.6e-06 28.5 0.0 5.9e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM65345.1 - 3.5e-05 23.9 0.0 0.00018 21.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KUM65345.1 - 0.01 15.0 0.0 0.03 13.4 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 KUM65345.1 - 0.043 14.1 0.1 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain VasI PF11319.8 KUM65345.1 - 0.095 12.4 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 ATPase_2 PF01637.18 KUM65345.1 - 0.14 12.0 1.6 0.23 11.3 0.0 2.2 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea DUF1811 PF08838.10 KUM65345.1 - 0.29 11.4 2.1 20 5.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1811) Cut8 PF08559.10 KUM65346.1 - 2.9e-80 269.4 0.0 3.6e-80 269.1 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein IKI3 PF04762.12 KUM65347.1 - 0 1037.5 0.0 0 1037.2 0.0 1.1 1 0 0 1 1 1 1 IKI3 family UME PF08064.13 KUM65347.1 - 0.025 14.5 0.2 0.5 10.3 0.0 2.8 3 0 0 3 3 3 0 UME (NUC010) domain Draxin PF15550.6 KUM65347.1 - 0.15 11.9 0.9 0.25 11.2 0.9 1.2 1 0 0 1 1 1 0 Draxin COX7C PF02935.16 KUM65348.1 - 6.1e-22 77.7 5.0 6.9e-22 77.5 4.2 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase subunit VIIc DSPc PF00782.20 KUM65349.1 - 1.1e-25 90.0 0.0 1.6e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KUM65349.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KUM65349.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Vfa1 PF08432.10 KUM65350.1 - 3e-60 203.6 14.3 3.4e-60 203.5 14.3 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 U79_P34 PF03064.16 KUM65350.1 - 0.017 14.5 12.5 0.023 14.0 12.5 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RR_TM4-6 PF06459.12 KUM65350.1 - 0.06 13.2 9.1 0.083 12.7 9.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 KUM65350.1 - 0.57 9.1 3.0 0.59 9.0 3.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 KUM65350.1 - 0.98 7.6 15.4 1.1 7.5 15.4 1.0 1 0 0 1 1 1 0 CDC45-like protein PPL5 PF18168.1 KUM65350.1 - 2.5 7.3 10.5 3.2 7.0 10.5 1.1 1 0 0 1 1 1 0 Prim-pol family 5 ATP11 PF06644.11 KUM65350.1 - 3.7 7.3 11.2 4.6 6.9 11.2 1.1 1 0 0 1 1 1 0 ATP11 protein Presenilin PF01080.17 KUM65350.1 - 3.8 6.2 8.7 4.4 6.0 8.7 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 KUM65350.1 - 4 7.4 4.7 4.6 7.2 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NPR3 PF03666.13 KUM65350.1 - 7.4 5.2 14.2 8.8 5.0 14.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Arylsulfotran_2 PF14269.6 KUM65351.1 - 2.2e-31 109.4 0.1 2.8e-31 109.0 0.1 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KUM65351.1 - 0.061 12.2 0.0 0.069 12.0 0.0 1.1 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) Abhydrolase_1 PF00561.20 KUM65353.1 - 1.7e-14 54.1 0.0 2.4e-14 53.6 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KUM65353.1 - 3.5e-08 34.3 0.0 4.4e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM65353.1 - 1.5e-05 24.4 0.0 3e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ufd2P_core PF10408.9 KUM65354.1 - 2.4e-218 726.8 12.4 2.9e-218 726.5 12.4 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KUM65354.1 - 1.7e-24 85.8 0.3 5.3e-24 84.2 0.3 1.9 1 0 0 1 1 1 1 U-box domain Peptidase_S8 PF00082.22 KUM65355.1 - 4.2e-25 88.6 2.7 1.1e-24 87.2 2.7 1.7 1 0 0 1 1 1 1 Subtilase family DUF1977 PF09320.11 KUM65356.1 - 1.3e-30 105.8 0.0 3e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KUM65356.1 - 6.9e-22 77.3 0.6 1.5e-21 76.3 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain Aim19 PF10315.9 KUM65357.1 - 0.002 18.4 0.1 0.0026 18.1 0.1 1.3 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF4536 PF15055.6 KUM65357.1 - 0.0094 16.2 0.7 0.02 15.1 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) CTP_transf_like PF01467.26 KUM65358.1 - 7.4e-05 23.0 0.0 0.00024 21.3 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase-like Ydc2-catalyt PF09159.10 KUM65360.1 - 8e-91 304.6 0.0 1.8e-90 303.5 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 KUM65360.1 - 0.00088 19.4 0.0 2.7 8.1 0.0 3.5 3 0 0 3 3 3 1 Poxvirus A22 protein SAP PF02037.27 KUM65360.1 - 0.019 14.7 0.1 0.036 13.8 0.1 1.5 1 0 0 1 1 1 0 SAP domain SPX PF03105.19 KUM65360.1 - 0.78 9.6 5.6 1.1 9.0 5.6 1.2 1 0 0 1 1 1 0 SPX domain Tcp11 PF05794.13 KUM65361.1 - 2.5e-116 389.4 0.1 3.2e-116 389.0 0.1 1.1 1 0 0 1 1 1 1 T-complex protein 11 Peptidase_M75 PF09375.10 KUM65361.1 - 0.007 15.9 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Imelysin Peptidase_S10 PF00450.22 KUM65362.1 - 5.5e-72 243.5 0.0 1.3e-71 242.2 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 KUM65362.1 - 0.0078 16.8 0.1 1.1 9.8 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Cofilin_ADF PF00241.20 KUM65363.1 - 7.6e-10 38.6 0.2 3.1e-05 23.8 0.1 2.0 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF3712 PF12505.8 KUM65364.1 - 0.0066 16.7 0.4 0.097 12.9 0.3 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KUM65364.1 - 0.0087 16.6 0.0 8.4 7.0 0.0 3.5 2 0 0 2 2 2 2 Late embryogenesis abundant protein OTCace PF00185.24 KUM65365.1 - 5.6e-46 156.5 0.0 8.5e-46 155.9 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KUM65365.1 - 1.3e-45 155.1 0.1 2.1e-45 154.4 0.1 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Bac_rhamnosid PF05592.11 KUM65365.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain KH_1 PF00013.29 KUM65366.1 - 9.1e-09 35.0 0.0 5.9e-05 22.8 0.0 2.7 2 0 0 2 2 2 2 KH domain ALS_ss_C PF10369.9 KUM65367.1 - 2.8e-15 56.3 0.0 4.8e-14 52.3 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KUM65367.1 - 7.3e-13 48.0 0.1 1.3e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KUM65367.1 - 6e-08 32.4 0.0 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KUM65367.1 - 0.021 14.8 0.1 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 ACT domain PPR_2 PF13041.6 KUM65368.1 - 1.7e-10 40.9 0.1 0.0034 17.5 0.0 3.7 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.20 KUM65368.1 - 4.4e-06 26.6 0.2 0.047 13.9 0.0 4.0 3 0 0 3 3 3 2 PPR repeat TPR_14 PF13428.6 KUM65368.1 - 0.0089 16.8 0.1 1.5 9.8 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat PPR_long PF17177.4 KUM65368.1 - 0.012 15.0 0.0 0.04 13.3 0.0 1.8 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 KUM65368.1 - 0.036 14.1 0.0 27 4.9 0.0 3.3 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Helicase_C PF00271.31 KUM65369.1 - 8.7e-16 58.3 0.0 2.4e-11 43.9 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 KUM65369.1 - 1.1e-15 57.9 0.0 2e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KUM65369.1 - 1.9e-07 31.7 0.7 1.9e-07 31.7 0.7 2.0 2 0 0 2 2 2 1 RecQ zinc-binding DUF4082 PF13313.6 KUM65369.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) SOG2 PF10428.9 KUM65370.1 - 2.5e-105 353.6 0.2 1e-56 193.3 0.8 4.1 3 1 1 4 4 4 2 RAM signalling pathway protein LRR_4 PF12799.7 KUM65370.1 - 9.1e-12 45.0 4.2 9.8e-06 25.8 1.8 3.6 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KUM65370.1 - 9.8e-12 44.5 4.9 7.1e-10 38.5 3.0 2.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KUM65370.1 - 0.003 17.9 2.6 21 6.1 0.2 5.1 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 KUM65370.1 - 0.7 10.1 6.2 17 5.8 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich repeat MRP-S25 PF13741.6 KUM65371.1 - 2e-84 282.8 3.6 2.3e-84 282.5 3.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KUM65371.1 - 0.05 13.9 0.5 8.4 6.7 0.1 2.5 1 1 0 2 2 2 0 Mitochondrial ribosomal protein S23 FAD_binding_3 PF01494.19 KUM65372.1 - 2.6e-14 53.2 0.1 1.3e-13 51.0 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KUM65372.1 - 0.0036 16.2 0.3 0.22 10.3 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase SE PF08491.10 KUM65372.1 - 0.015 14.4 0.0 3.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.14 KUM65372.1 - 0.03 13.6 0.6 0.49 9.6 0.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM65372.1 - 0.056 13.7 0.4 0.17 12.1 0.4 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF3984 PF13136.6 KUM65373.1 - 1.9e-104 349.7 17.6 2.2e-104 349.5 17.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) TatD_DNase PF01026.21 KUM65374.1 - 8.9e-48 162.9 0.0 1e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Lactamase_B PF00753.27 KUM65375.1 - 0.0023 18.0 0.0 0.003 17.6 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Asp PF00026.23 KUM65377.1 - 2.6e-73 247.2 3.5 2.6e-73 247.2 3.5 1.5 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KUM65377.1 - 1.2e-10 42.0 11.9 7.4e-10 39.3 3.7 3.2 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KUM65377.1 - 0.00024 20.9 0.0 0.00094 19.0 0.0 1.8 1 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KUM65377.1 - 0.00033 21.2 0.0 0.36 11.5 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KUM65377.1 - 0.068 13.7 0.0 8.7 7.0 0.0 2.8 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease SSP160 PF06933.11 KUM65377.1 - 0.08 11.1 17.7 0.12 10.5 17.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF515 PF04415.12 KUM65377.1 - 0.24 9.7 12.9 0.37 9.1 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) FMN_dh PF01070.18 KUM65379.1 - 1.1e-113 379.9 0.0 1.3e-113 379.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KUM65379.1 - 9.2e-19 67.4 0.0 1.9e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KUM65379.1 - 8.6e-05 21.8 0.0 0.00016 20.9 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KUM65379.1 - 0.0049 15.9 0.1 0.013 14.5 0.1 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KUM65379.1 - 0.011 15.0 0.0 2 7.7 0.0 2.4 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG NMO PF03060.15 KUM65379.1 - 0.02 14.3 0.1 0.094 12.1 0.0 1.8 1 1 1 2 2 2 0 Nitronate monooxygenase DAG1 PF05454.11 KUM65379.1 - 0.059 12.7 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Nup54_C PF18437.1 KUM65379.1 - 0.18 11.8 0.1 0.36 10.8 0.1 1.5 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain zf-C2H2 PF00096.26 KUM65380.1 - 0.0033 17.8 23.1 0.03 14.8 2.6 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-FCS PF06467.14 KUM65380.1 - 0.064 13.2 1.9 4.6 7.3 0.2 2.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.6 KUM65380.1 - 0.08 13.4 0.5 0.08 13.4 0.5 3.2 5 0 0 5 5 5 0 Zinc-finger double domain zf-CHCC PF10276.9 KUM65380.1 - 0.32 11.1 3.9 6.7 6.9 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_4 PF13894.6 KUM65380.1 - 0.66 11.0 22.9 1.8 9.6 3.1 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KUM65380.1 - 2 8.8 15.0 1.1 9.6 4.4 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FMN_dh PF01070.18 KUM65383.1 - 1.1e-107 360.1 0.0 1.3e-107 359.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KUM65383.1 - 0.00016 20.8 0.2 0.00029 19.9 0.2 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KUM65383.1 - 0.0089 15.5 0.7 0.051 13.0 0.6 2.0 1 1 1 2 2 2 1 Histidine biosynthesis protein Glu_synthase PF01645.17 KUM65383.1 - 0.014 14.6 0.1 0.02 14.1 0.1 1.1 1 0 0 1 1 1 0 Conserved region in glutamate synthase ThiG PF05690.14 KUM65383.1 - 0.11 11.8 0.7 0.76 9.0 0.5 2.1 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG Steroid_dh PF02544.16 KUM65384.1 - 2.9e-16 59.8 0.9 6.7e-06 26.2 0.3 3.7 4 0 0 4 4 4 3 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KUM65384.1 - 0.018 14.6 1.2 0.049 13.1 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Ldh_2 PF02615.14 KUM65387.1 - 6.7e-123 410.1 0.2 8.5e-123 409.7 0.2 1.1 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase adh_short PF00106.25 KUM65388.1 - 2.5e-13 49.9 0.0 1.5e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KUM65388.1 - 0.0012 18.8 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KUM65388.1 - 0.0085 15.3 0.0 0.02 14.1 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 KUM65388.1 - 0.14 12.6 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 KUM65388.1 - 0.22 11.0 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.18 KUM65389.1 - 6.7e-09 35.2 0.2 1.2e-08 34.3 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM65389.1 - 1.8e-05 24.8 7.9 3.2e-05 23.9 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0506 PF11703.8 KUM65389.1 - 1.7 9.1 10.1 0.15 12.5 5.2 1.7 2 0 0 2 2 2 0 UPF0506 p450 PF00067.22 KUM65390.1 - 3.6e-67 227.1 0.0 4.5e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Dus PF01207.17 KUM65391.1 - 3.4e-40 138.1 0.0 8.1e-28 97.4 0.0 2.8 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 KUM65391.1 - 1e-05 25.2 0.7 1e-05 25.2 0.7 2.5 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KUM65391.1 - 3.8e-05 23.6 5.3 0.0012 18.8 0.5 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KUM65391.1 - 0.0014 19.3 6.6 0.028 15.1 2.3 2.7 1 1 1 2 2 2 2 Torus domain zf-CCCH PF00642.24 KUM65391.1 - 0.0025 17.7 0.4 0.0025 17.7 0.4 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Peptidase_M24 PF00557.24 KUM65392.1 - 2.5e-22 79.6 0.0 3.1e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Bap31 PF05529.12 KUM65393.1 - 4.9e-50 168.9 5.2 6e-50 168.6 5.2 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KUM65393.1 - 7.2e-14 51.5 3.9 1.2e-13 50.8 3.9 1.4 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain FlxA PF14282.6 KUM65393.1 - 0.03 14.3 0.9 0.049 13.6 0.9 1.3 1 0 0 1 1 1 0 FlxA-like protein p450 PF00067.22 KUM65394.1 - 2.8e-11 42.8 0.1 3.5e-11 42.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 KUM65395.1 - 1.5e-15 57.4 0.0 2.7e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM65395.1 - 4.1e-09 37.0 0.0 1.2e-08 35.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM65395.1 - 2.9e-07 31.1 0.0 7e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM65395.1 - 3.9e-05 23.5 0.0 8e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM65395.1 - 4.2e-05 24.1 0.0 9.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KUM65395.1 - 0.0001 22.5 0.0 0.00026 21.1 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.14 KUM65395.1 - 0.002 17.7 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KUM65395.1 - 0.0057 16.1 0.0 0.0093 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KUM65395.1 - 0.0063 16.0 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 KUM65395.1 - 0.1 11.9 0.0 0.69 9.2 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KUM65395.1 - 0.16 11.3 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TFIIA PF03153.13 KUM65396.1 - 5.9e-83 280.2 3.6 9.7e-83 279.5 3.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-C2H2 PF00096.26 KUM65397.1 - 2.3e-05 24.6 10.2 0.071 13.6 1.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KUM65397.1 - 3.6e-05 24.0 0.6 0.024 14.8 0.0 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KUM65397.1 - 0.00014 22.4 11.8 0.03 15.1 1.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KUM65397.1 - 0.013 15.8 1.0 1.2 9.5 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KUM65397.1 - 0.02 15.3 0.5 0.02 15.3 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger double domain DUF4719 PF15843.5 KUM65397.1 - 0.28 11.3 0.0 0.28 11.3 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4719) Kelch_4 PF13418.6 KUM65398.1 - 6.4e-26 90.1 9.1 1e-06 28.6 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KUM65398.1 - 2.3e-23 81.7 0.3 0.00024 21.0 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KUM65398.1 - 6.1e-21 73.5 0.3 9.1e-06 25.5 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 KUM65398.1 - 7.9e-21 73.9 6.4 2e-08 34.3 0.1 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KUM65398.1 - 3.5e-20 71.5 1.0 2.9e-05 24.2 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KUM65398.1 - 4.2e-18 64.7 0.1 7.4e-05 22.3 0.1 4.7 4 0 0 4 4 4 4 Kelch motif BTB PF00651.31 KUM65398.1 - 5.2e-09 36.3 0.0 9.1e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain bPH_6 PF10756.9 KUM65398.1 - 0.035 14.2 0.0 0.13 12.4 0.0 2.0 1 0 0 1 1 1 0 Bacterial PH domain BACK PF07707.15 KUM65398.1 - 0.18 11.9 0.0 0.44 10.7 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch ANAPC4_WD40 PF12894.7 KUM65399.1 - 2.3e-15 56.7 5.8 5.2e-06 26.7 0.2 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KUM65399.1 - 9.4e-15 54.8 18.2 0.00057 20.6 0.0 6.9 6 1 1 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KUM65399.1 - 1.2e-05 24.4 0.1 0.0014 17.7 0.0 3.1 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KUM65399.1 - 0.00053 19.9 2.4 0.011 15.6 0.2 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Amidase PF01425.21 KUM65401.1 - 1.1e-52 179.5 0.6 3.9e-45 154.7 0.7 2.7 2 1 0 2 2 2 2 Amidase MFS_1 PF07690.16 KUM65402.1 - 2.5e-28 99.0 32.5 2.5e-28 99.0 32.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KUM65402.1 - 0.00021 20.7 8.7 0.00021 20.7 8.7 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Tetraspanin PF00335.20 KUM65402.1 - 6.1 6.5 10.2 0.63 9.7 0.8 2.9 2 1 1 3 3 3 0 Tetraspanin family MMM1 PF10296.9 KUM65404.1 - 5.4e-06 25.7 0.0 1.2e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 DUF1280 PF06918.14 KUM65405.1 - 0.034 13.7 1.1 0.063 12.9 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) zf-Di19 PF05605.12 KUM65406.1 - 0.00029 21.1 19.9 0.17 12.2 0.7 4.8 4 0 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding DUF4451 PF14616.6 KUM65406.1 - 0.00077 19.7 0.9 1.5 9.1 1.4 3.8 1 1 2 3 3 3 1 Domain of unknown function (DUF4451) zf-C2H2 PF00096.26 KUM65406.1 - 0.0055 17.1 27.5 2.7 8.6 0.7 6.8 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM65406.1 - 0.0087 16.8 34.2 2.9 9.0 0.2 7.8 7 1 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KUM65406.1 - 0.024 15.0 3.6 0.66 10.3 0.5 3.3 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF1403 PF07183.11 KUM65406.1 - 0.033 13.7 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1403) Clusterin PF01093.17 KUM65406.1 - 0.13 11.3 3.3 0.082 12.0 1.0 1.8 2 1 1 3 3 3 0 Clusterin zf-C2H2_3rep PF18868.1 KUM65406.1 - 0.32 11.7 5.9 3.1 8.5 0.2 3.9 2 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KUM65406.1 - 3.7 8.1 7.0 24 5.5 0.0 4.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Utp11 PF03998.13 KUM65407.1 - 9.3e-60 202.6 29.7 1.1e-59 202.4 29.7 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KUM65407.1 - 0.035 13.4 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DTHCT PF08070.11 KUM65407.1 - 0.043 14.6 1.0 0.043 14.6 1.0 3.5 1 1 2 3 3 3 0 DTHCT (NUC029) region PhoU PF01895.19 KUM65407.1 - 0.2 12.1 2.1 0.26 11.8 0.1 2.1 2 0 0 2 2 2 0 PhoU domain Cmc1 PF08583.10 KUM65408.1 - 1.2e-15 57.2 2.5 2.3e-15 56.3 2.5 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 KUM65408.1 - 0.0014 18.6 0.7 0.0022 17.9 0.7 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Arylsulfotran_2 PF14269.6 KUM65409.1 - 1.7e-54 185.3 5.0 2.3e-54 184.8 5.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KUM65409.1 - 1.4e-17 63.7 0.6 5.1e-16 58.6 0.6 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DSBA PF01323.20 KUM65409.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Glyco_hydro_47 PF01532.20 KUM65410.1 - 1.7e-142 475.5 0.0 2e-142 475.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Histidinol_dh PF00815.20 KUM65411.1 - 8.2e-159 529.0 3.4 1.2e-158 528.4 3.4 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KUM65411.1 - 5.1e-23 80.7 0.1 1.1e-22 79.6 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KUM65411.1 - 8e-15 55.0 0.2 1.9e-14 53.8 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase CIAPIN1 PF05093.13 KUM65412.1 - 1.2e-42 144.5 3.5 2.2e-42 143.6 3.5 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KUM65412.1 - 2.1e-37 128.3 0.1 3e-37 127.8 0.1 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus TFIID-31kDa PF02291.15 KUM65413.1 - 1.1e-45 154.6 0.0 1.5e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Mucin PF01456.17 KUM65413.1 - 0.22 11.5 8.2 0.44 10.5 8.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein LNS2 PF08235.13 KUM65414.1 - 3.6e-96 321.0 0.0 5e-96 320.5 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KUM65414.1 - 2.4e-40 136.6 0.0 4.7e-40 135.7 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 KUM65414.1 - 0.0013 18.4 0.0 0.11 12.1 0.0 2.6 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) WRNPLPNID PF15017.6 KUM65414.1 - 0.26 12.2 16.2 0.85 10.5 16.2 2.0 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Nop14 PF04147.12 KUM65414.1 - 1.8 6.7 14.1 2.3 6.3 14.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KUM65414.1 - 6.2 5.0 9.4 9.1 4.4 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein TPR_2 PF07719.17 KUM65415.1 - 3.8e-08 32.8 14.2 0.00014 21.7 0.0 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KUM65415.1 - 4.2e-06 27.2 1.7 0.13 12.8 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KUM65415.1 - 3.2e-05 23.8 0.9 0.98 9.8 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KUM65415.1 - 0.00016 21.3 8.9 0.0019 18.0 0.0 5.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KUM65415.1 - 0.00026 20.8 4.2 1.2 9.3 0.1 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KUM65415.1 - 0.0011 18.6 0.0 2.9 7.7 0.0 4.8 6 0 0 6 6 6 1 TPR repeat TPR_4 PF07721.14 KUM65415.1 - 0.077 13.7 3.8 0.45 11.3 2.8 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KUM65415.1 - 0.11 12.4 5.9 7.3 6.6 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KUM65415.1 - 0.27 11.6 9.4 0.2 12.0 1.1 4.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KUM65415.1 - 0.68 10.9 16.0 20 6.3 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat SR-25 PF10500.9 KUM65416.1 - 4.1 6.9 5.8 6.5 6.3 5.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sod_Fe_N PF00081.22 KUM65417.1 - 8.8e-34 115.8 1.8 8.8e-34 115.8 1.8 1.8 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 KUM65417.1 - 7.4e-32 109.6 0.1 1.7e-31 108.4 0.0 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain ACPS PF01648.20 KUM65417.1 - 0.025 14.7 0.0 0.043 13.9 0.0 1.6 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase superfamily Sugar_tr PF00083.24 KUM65419.1 - 7.7e-86 288.7 29.1 9.2e-86 288.5 29.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM65419.1 - 1.9e-30 106.0 46.2 2.1e-21 76.3 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.7 KUM65419.1 - 0.0093 16.1 5.9 0.0093 16.1 5.9 4.2 3 2 1 5 5 5 1 Protein of unknown function (DUF3792) DAO PF01266.24 KUM65420.1 - 1e-38 133.8 0.0 1.2e-38 133.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM65420.1 - 0.00029 20.2 0.0 0.28 10.4 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM65420.1 - 0.0065 16.5 0.2 3.6 7.6 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 KUM65420.1 - 0.0088 15.2 0.1 0.19 10.8 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Ldh_1_N PF00056.23 KUM65420.1 - 0.064 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain UNC-93 PF05978.16 KUM65421.1 - 4.6e-10 39.4 3.8 4.6e-10 39.4 3.8 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KUM65421.1 - 1.2e-08 34.3 30.1 1.2e-08 34.3 30.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM65421.1 - 0.00037 19.5 8.2 0.00037 19.5 8.2 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter Glyco_hydro_1 PF00232.18 KUM65423.1 - 7.3e-155 515.8 0.0 9.1e-155 515.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Pkinase PF00069.25 KUM65424.1 - 5.6e-63 212.8 0.0 9.9e-63 212.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM65424.1 - 1.9e-35 122.4 0.0 6.8e-30 104.2 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KUM65424.1 - 3.3e-06 26.6 0.0 0.0044 16.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KUM65424.1 - 0.00014 21.9 0.2 0.0015 18.5 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KUM65424.1 - 0.00091 18.9 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KUM65424.1 - 0.021 14.2 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KUM65424.1 - 0.028 13.4 0.1 0.046 12.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CDC45 PF02724.14 KUM65424.1 - 8.1 4.6 9.0 16 3.7 9.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Zn_clus PF00172.18 KUM65425.1 - 7e-06 26.1 13.7 1.2e-05 25.3 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ninjurin PF04923.12 KUM65425.1 - 0.14 12.1 1.7 6.8 6.7 0.1 2.5 2 1 0 2 2 2 0 Ninjurin Mei5 PF10376.9 KUM65426.1 - 0.00027 20.9 4.7 0.012 15.4 4.7 2.5 1 1 0 1 1 1 1 Double-strand recombination repair protein DUF848 PF05852.11 KUM65426.1 - 0.02 15.0 0.1 0.043 13.9 0.1 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Med4 PF10018.9 KUM65426.1 - 0.043 13.5 7.1 0.21 11.3 1.3 2.2 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 WD40 PF00400.32 KUM65427.1 - 3e-13 50.0 10.6 3.6e-05 24.4 0.3 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM65427.1 - 6.4e-11 42.4 0.5 0.0068 16.7 0.0 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KUM65427.1 - 1.6e-05 24.8 0.0 0.071 13.0 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KUM65427.1 - 0.016 13.8 0.0 0.054 12.0 0.0 1.9 2 1 0 2 2 2 0 Cytochrome D1 heme domain Sel1 PF08238.12 KUM65428.1 - 1.7e-34 117.5 34.6 1.6e-05 25.4 0.4 11.9 11 1 1 12 12 12 8 Sel1 repeat TPR_7 PF13176.6 KUM65428.1 - 0.03 14.4 5.3 14 6.0 0.0 5.1 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KUM65428.1 - 0.19 12.1 3.7 18 5.9 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat MobL PF18555.1 KUM65428.1 - 0.35 10.1 1.4 0.57 9.4 1.4 1.3 1 0 0 1 1 1 0 MobL relaxases TPR_1 PF00515.28 KUM65428.1 - 5.1 7.1 13.1 9.6 6.2 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat RNA_pol_Rpb1_1 PF04997.12 KUM65429.1 - 2e-111 372.3 0.0 3.1e-111 371.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KUM65429.1 - 3.3e-103 344.8 0.2 5.3e-103 344.1 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KUM65429.1 - 3.7e-75 251.7 0.0 7.8e-75 250.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KUM65429.1 - 1.2e-64 217.7 1.6 2.5e-64 216.6 1.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KUM65429.1 - 1.5e-45 154.5 9.2 2e-44 150.9 7.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KUM65429.1 - 5.8e-45 153.0 0.0 1.4e-44 151.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KUM65429.1 - 6.1e-38 129.1 0.1 1.8e-37 127.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KUM65429.1 - 4.6e-17 61.4 203.9 0.0015 18.8 0.1 14.4 12 2 2 14 14 14 13 RNA polymerase Rpb1 C-terminal repeat YorP PF09629.10 KUM65429.1 - 0.09 13.0 0.0 1.6 9.0 0.0 2.6 3 0 0 3 3 3 0 YorP protein Thg1 PF04446.12 KUM65430.1 - 2.2e-52 176.3 0.0 3.2e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KUM65430.1 - 3.8e-50 169.1 0.6 5.8e-50 168.5 0.6 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain fn3 PF00041.21 KUM65431.1 - 9.1e-07 29.1 0.0 2.2e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain WD40 PF00400.32 KUM65432.1 - 8e-13 48.6 1.8 0.0024 18.7 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF962 PF06127.11 KUM65432.1 - 0.16 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF962) Lipase_GDSL_2 PF13472.6 KUM65435.1 - 7.4e-17 62.3 0.0 1.2e-16 61.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KUM65435.1 - 7.1e-10 39.2 0.0 5.1e-09 36.4 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF993 PF06187.11 KUM65435.1 - 0.0092 14.9 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF993) AP_endonuc_2 PF01261.24 KUM65435.1 - 0.014 14.9 0.0 0.051 13.0 0.0 1.9 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Glyco_tran_WecB PF03808.13 KUM65435.1 - 0.062 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DUF4416 PF14385.6 KUM65435.1 - 0.19 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) Zn_clus PF00172.18 KUM65436.1 - 1.8e-07 31.2 16.0 3e-07 30.5 16.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM65436.1 - 1.2e-06 27.6 1.7 2.1e-06 26.8 1.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CVNH PF08881.10 KUM65437.1 - 1.9e-21 76.6 0.1 3.5e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 CVNH domain Peptidase_C12 PF01088.21 KUM65438.1 - 5e-71 238.8 0.0 6.4e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KUM65438.1 - 8.3e-09 35.2 1.0 1.2e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases Phosphoesterase PF04185.14 KUM65440.1 - 4e-71 240.1 4.7 6e-71 239.5 4.7 1.2 1 0 0 1 1 1 1 Phosphoesterase family GPI-anchored PF10342.9 KUM65441.1 - 0.001 19.8 0.0 0.0018 19.0 0.0 1.5 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GalBD_like PF17974.1 KUM65441.1 - 0.039 14.1 0.1 1.2 9.3 0.0 2.0 2 0 0 2 2 2 0 Galactose-binding domain-like Cupin_8 PF13621.6 KUM65442.1 - 3.8e-31 108.7 0.0 8.5e-31 107.6 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KUM65442.1 - 6.3e-05 22.6 0.1 0.0091 15.5 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 KUM65442.1 - 0.06 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase SBD_N PF07005.11 KUM65443.1 - 5.1e-58 196.5 0.0 8e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 Sugar-binding N-terminal domain NBD_C PF17042.5 KUM65443.1 - 3.1e-41 141.7 1.7 7e-41 140.6 1.7 1.6 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain Cofilin_ADF PF00241.20 KUM65444.1 - 3.6e-34 117.2 1.0 4.1e-34 117.0 1.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein GTP1_OBG PF01018.22 KUM65445.1 - 2.1e-40 137.9 1.6 1.1e-30 106.3 3.1 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KUM65445.1 - 2e-22 79.4 0.0 3.9e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KUM65445.1 - 1.9e-08 34.0 0.1 4.2e-08 32.9 0.1 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 KUM65445.1 - 0.0043 17.6 0.4 0.031 14.8 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Ploopntkinase3 PF18751.1 KUM65445.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 MeaB PF03308.16 KUM65445.1 - 0.19 10.7 0.1 1.2 8.0 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ccdc124 PF06244.12 KUM65446.1 - 4.6e-30 104.8 25.6 1.2e-28 100.2 25.6 2.2 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Zip PF02535.22 KUM65446.1 - 5.2 6.2 6.4 7.7 5.6 6.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 KUM65447.1 - 3.7e-245 815.1 3.1 1e-243 810.4 3.1 2.9 1 1 0 1 1 1 1 CDC45-like protein Tir_receptor_N PF07490.11 KUM65447.1 - 0.013 15.4 0.8 0.036 13.9 0.8 1.7 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Cwf_Cwc_15 PF04889.12 KUM65447.1 - 0.028 14.1 24.8 0.023 14.4 8.1 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KUM65447.1 - 0.18 11.1 37.1 0.084 12.2 15.3 2.2 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 KUM65447.1 - 0.48 8.6 27.1 0.32 9.2 10.2 2.1 2 0 0 2 2 2 0 Nop14-like family DUF5421 PF17458.2 KUM65447.1 - 0.88 8.9 8.0 1.7 7.9 8.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5421) SDA1 PF05285.12 KUM65447.1 - 2.3 7.5 29.6 1.8 7.9 7.9 2.2 2 0 0 2 2 2 0 SDA1 SPX PF03105.19 KUM65447.1 - 3.5 7.4 24.2 1.2 9.0 2.0 2.2 2 0 0 2 2 2 0 SPX domain DDHD PF02862.17 KUM65447.1 - 4.1 7.5 9.0 0.84 9.7 0.5 2.3 2 0 0 2 2 2 0 DDHD domain RR_TM4-6 PF06459.12 KUM65447.1 - 4.5 7.0 21.3 0.24 11.2 9.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 KUM65447.1 - 9.3 6.2 15.2 0.062 13.3 3.8 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Peptidase_C13 PF01650.18 KUM65448.1 - 7.5e-40 137.1 0.1 1e-39 136.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Pyr_redox_2 PF07992.14 KUM65450.1 - 1.8e-37 129.2 0.0 2.3e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM65450.1 - 2.2e-12 47.4 0.8 4.8e-10 39.8 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KUM65450.1 - 7.3e-07 28.6 1.4 0.00021 20.5 0.0 3.5 3 1 1 4 4 4 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KUM65450.1 - 0.00019 20.9 0.2 0.059 12.7 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KUM65450.1 - 0.0014 17.9 0.2 0.13 11.5 0.0 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KUM65450.1 - 0.0056 16.0 1.1 0.0056 16.0 1.1 2.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM65450.1 - 0.031 13.9 3.8 5.7 6.4 0.0 3.7 3 1 1 4 4 4 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 KUM65450.1 - 0.042 13.0 0.4 10 5.1 0.2 2.6 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) MFS_1 PF07690.16 KUM65451.1 - 7.6e-39 133.6 22.1 2.2e-35 122.2 15.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KUM65451.1 - 3e-07 29.7 15.9 0.00017 20.6 10.8 3.2 2 1 1 3 3 3 2 MFS_1 like family OATP PF03137.20 KUM65451.1 - 6e-05 21.5 7.9 0.00011 20.6 5.2 2.5 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KUM65451.1 - 0.0009 17.8 14.1 0.0068 14.9 7.8 2.5 3 0 0 3 3 3 2 Transmembrane secretion effector MFS_4 PF06779.14 KUM65451.1 - 0.0011 18.3 14.5 0.05 12.9 9.2 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_5 PF05631.14 KUM65451.1 - 0.0029 16.6 0.6 0.0054 15.7 0.6 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM DUF5407 PF17401.2 KUM65452.1 - 0.15 12.4 2.3 0.16 12.2 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5407) VWA_2 PF13519.6 KUM65453.1 - 0.014 16.0 0.0 0.03 15.0 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.28 KUM65453.1 - 0.02 15.1 0.0 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain Fungal_trans_2 PF11951.8 KUM65454.1 - 3.4e-12 45.9 2.3 1e-10 41.0 2.3 2.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zinc_ribbon_2 PF13240.6 KUM65455.1 - 0.023 14.4 0.3 0.053 13.3 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain GFA PF04828.14 KUM65455.1 - 0.046 14.0 0.0 0.088 13.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Maf PF02545.14 KUM65456.1 - 9.3e-48 162.2 0.0 1.1e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein eIF_4EBP PF05456.11 KUM65456.1 - 0.31 11.0 1.6 0.5 10.3 1.6 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) CybS PF05328.12 KUM65457.1 - 9.9e-51 170.9 0.0 1.3e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit ADH_zinc_N PF00107.26 KUM65458.1 - 5.8e-22 78.1 0.0 8.6e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KUM65458.1 - 8.2e-20 70.7 0.0 1.4e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KUM65458.1 - 6.2e-08 33.8 0.0 1.9e-07 32.2 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase p450 PF00067.22 KUM65459.1 - 2.4e-51 174.9 0.0 3.2e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Choline_kinase PF01633.20 KUM65460.1 - 6.1e-62 209.0 0.1 3.2e-61 206.6 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 KUM65460.1 - 5.9e-17 61.1 0.0 1.5e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 KUM65460.1 - 5.4e-05 23.2 0.1 0.00017 21.6 0.1 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family WD40 PF00400.32 KUM65461.1 - 6.3e-15 55.3 15.9 0.0036 18.1 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Mem_trans PF03547.18 KUM65462.1 - 1.2e-56 191.8 1.1 3.2e-56 190.4 1.1 1.6 1 1 0 1 1 1 1 Membrane transport protein DUF1240 PF06836.12 KUM65462.1 - 5.4 7.6 7.1 0.29 11.7 0.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) TPP_enzyme_N PF02776.18 KUM65463.1 - 3.7e-29 101.5 0.2 5.3e-29 101.0 0.2 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KUM65463.1 - 1.4e-20 73.4 0.0 2.3e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KUM65463.1 - 6.4e-17 61.7 0.0 3.4e-16 59.4 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Sulfotransfer_3 PF13469.6 KUM65464.1 - 0.0011 19.4 0.0 0.0033 17.9 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family Aminotran_1_2 PF00155.21 KUM65465.1 - 6.5e-16 58.4 0.0 7.7e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HpcH_HpaI PF03328.14 KUM65466.1 - 1.4e-25 89.8 0.1 1.9e-25 89.3 0.1 1.3 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DEAD PF00270.29 KUM65467.1 - 1.8e-42 145.1 0.1 2.7e-42 144.5 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM65467.1 - 2.8e-18 66.3 0.2 9.6e-18 64.6 0.2 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM65467.1 - 0.00047 20.2 0.0 0.0008 19.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KUM65467.1 - 0.087 12.1 0.0 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 SecA DEAD-like domain ERCC3_RAD25_C PF16203.5 KUM65467.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Cys_Met_Meta_PP PF01053.20 KUM65468.1 - 1.2e-29 103.1 0.0 1.7e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KUM65468.1 - 9.2e-07 28.4 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DnaJ PF00226.31 KUM65469.1 - 2.1e-21 75.8 0.7 4.6e-21 74.7 0.7 1.6 1 0 0 1 1 1 1 DnaJ domain Adenylsucc_synt PF00709.21 KUM65470.1 - 1.2e-165 551.6 0.0 1.3e-165 551.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase KHA PF11834.8 KUM65470.1 - 0.099 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel MFS_1 PF07690.16 KUM65471.1 - 1.2e-39 136.2 10.4 8.9e-30 103.8 0.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM65471.1 - 2.1e-12 46.7 5.9 1.1e-10 41.0 5.4 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 KUM65471.1 - 1.4 7.2 8.9 0.36 9.1 3.0 2.5 2 1 0 2 2 2 0 Transmembrane secretion effector Fungal_trans PF04082.18 KUM65472.1 - 5.9e-27 94.4 0.0 1e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM65472.1 - 1e-08 35.2 11.3 1.6e-08 34.5 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HLH PF00010.26 KUM65473.1 - 8.2e-09 35.3 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ANAPC4 PF12896.7 KUM65474.1 - 5.8e-70 234.9 1.3 8.1e-70 234.5 1.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KUM65474.1 - 6.7e-35 119.3 0.0 7.9e-32 109.4 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain HpaP PF09483.10 KUM65474.1 - 0.018 15.3 0.1 0.046 14.0 0.1 1.7 1 0 0 1 1 1 0 Type III secretion protein (HpaP) WD40 PF00400.32 KUM65474.1 - 0.023 15.6 1.5 0.77 10.7 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat IKI3 PF04762.12 KUM65474.1 - 0.056 11.5 0.0 6.7 4.6 0.0 2.2 2 0 0 2 2 2 0 IKI3 family Gmad1 PF10647.9 KUM65474.1 - 0.06 13.1 0.1 0.16 11.7 0.2 1.6 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain HEAT PF02985.22 KUM65475.1 - 1.2e-15 56.2 13.8 0.00025 21.0 0.1 8.3 10 1 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.6 KUM65475.1 - 3.8e-15 56.0 11.1 1.9e-10 41.0 0.0 5.9 5 2 1 6 6 6 3 HEAT-like repeat IBN_N PF03810.19 KUM65475.1 - 4.2e-07 29.8 1.7 1.8e-06 27.8 0.9 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KUM65475.1 - 3.1e-06 27.5 10.9 0.048 14.1 0.1 5.7 2 2 4 6 6 6 4 HEAT repeats HEAT_PBS PF03130.16 KUM65475.1 - 0.0069 17.0 0.2 39 5.3 0.0 5.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DRIM PF07539.12 KUM65475.1 - 0.019 13.3 0.0 0.86 7.8 0.0 2.3 2 0 0 2 2 2 0 Down-regulated in metastasis Arm PF00514.23 KUM65475.1 - 0.035 14.2 5.0 5.9 7.1 0.3 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KUM65475.1 - 0.13 12.3 0.1 1.3 9.0 0.0 2.5 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 KUM65475.1 - 0.14 12.5 0.1 1.6 9.1 0.1 2.5 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.8 KUM65476.1 - 0.00011 21.9 0.9 0.0063 16.1 0.1 2.9 2 1 2 4 4 4 1 CLASP N terminal DUF3385 PF11865.8 KUM65476.1 - 0.00013 21.9 2.2 0.28 11.1 0.7 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) Sec7_N PF12783.7 KUM65476.1 - 0.0018 18.2 0.1 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal RIX1 PF08167.12 KUM65476.1 - 0.0048 16.7 0.1 1.9 8.2 0.0 3.2 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis Cse1 PF08506.10 KUM65476.1 - 0.005 15.7 0.2 0.14 10.9 0.1 2.6 1 1 2 3 3 3 1 Cse1 Adaptin_N PF01602.20 KUM65476.1 - 0.0068 15.0 0.6 0.085 11.4 0.5 2.4 2 1 0 2 2 2 1 Adaptin N terminal region DRIM PF07539.12 KUM65476.1 - 0.031 12.6 0.8 2.3 6.4 0.0 2.4 3 0 0 3 3 3 0 Down-regulated in metastasis Ribosomal_S8 PF00410.19 KUM65477.1 - 2e-21 76.3 0.0 2.9e-21 75.7 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 His_Phos_1 PF00300.22 KUM65478.1 - 2.9e-13 50.0 0.0 2.5e-07 30.6 0.0 2.8 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) IMUP PF15761.5 KUM65479.1 - 0.16 12.7 1.5 0.4 11.4 1.5 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF1682 PF07946.14 KUM65479.1 - 1.4 8.0 4.3 2.1 7.4 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PS_Dcarbxylase PF02666.15 KUM65480.1 - 3.8e-76 255.1 0.0 1.8e-75 252.9 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Glyco_transf_90 PF05686.12 KUM65481.1 - 6.7e-19 68.1 4.3 2.1e-16 59.8 1.6 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 Taeniidae_ag PF05596.11 KUM65481.1 - 0.0094 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Taeniidae antigen Cu-oxidase_3 PF07732.15 KUM65482.1 - 1.3e-39 134.9 0.9 1.9e-36 124.7 0.0 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KUM65482.1 - 8e-31 106.6 9.0 9.2e-29 99.9 3.6 3.9 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KUM65482.1 - 2.9e-18 66.5 0.3 1.6e-17 64.1 0.0 2.4 4 0 0 4 4 4 1 Multicopper oxidase COesterase PF00135.28 KUM65483.1 - 9.8e-66 222.7 0.0 1.4e-65 222.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KUM65483.1 - 0.00013 21.9 0.9 0.00019 21.3 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KUM65483.1 - 0.005 17.5 1.0 0.013 16.1 0.9 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM65483.1 - 0.0086 15.7 0.2 0.016 14.9 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KUM65483.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KUM65483.1 - 0.041 13.2 0.0 0.066 12.5 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF1749 PF08538.10 KUM65483.1 - 0.19 10.8 0.0 0.39 9.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF1980 PF09323.10 KUM65484.1 - 0.014 15.3 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Presenilin PF01080.17 KUM65486.1 - 0.34 9.6 13.5 0.49 9.1 13.5 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 KUM65486.1 - 6 6.8 5.4 9.5 6.2 5.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop14 PF04147.12 KUM65486.1 - 7.5 4.6 25.2 11 4.1 25.2 1.2 1 0 0 1 1 1 0 Nop14-like family Rrp15p PF07890.12 KUM65488.1 - 1.1e-36 126.1 5.7 1.1e-36 126.1 5.7 1.9 2 0 0 2 2 2 1 Rrp15p DUF1373 PF07117.11 KUM65488.1 - 0.079 13.0 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) SRP54 PF00448.22 KUM65489.1 - 4.5e-75 251.6 2.8 8.2e-75 250.8 2.8 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KUM65489.1 - 1.6e-28 99.2 0.4 1.6e-28 99.2 0.4 4.1 3 1 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 KUM65489.1 - 1.2e-19 70.3 0.6 3e-19 69.0 0.6 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KUM65489.1 - 1.1e-07 31.7 0.2 2.9e-07 30.2 0.2 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KUM65489.1 - 6.7e-06 26.3 0.4 2.4e-05 24.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KUM65489.1 - 1.5e-05 25.4 1.3 3.1e-05 24.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KUM65489.1 - 2.8e-05 24.6 0.0 5.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KUM65489.1 - 0.00021 20.6 0.1 0.00056 19.2 0.1 1.7 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 KUM65489.1 - 0.00023 20.2 0.2 0.00023 20.2 0.2 2.7 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KUM65489.1 - 0.00091 19.0 0.5 0.0032 17.2 0.5 2.0 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KUM65489.1 - 0.001 19.0 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase CbiA PF01656.23 KUM65489.1 - 0.0022 18.1 0.0 0.0069 16.4 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 KUM65489.1 - 0.0036 17.3 0.6 0.0089 16.0 0.6 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit 6PF2K PF01591.18 KUM65489.1 - 0.0044 16.3 0.0 0.0078 15.5 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase ATP_bind_1 PF03029.17 KUM65489.1 - 0.0046 16.8 0.6 0.015 15.1 0.1 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KUM65489.1 - 0.0051 16.3 1.5 2 7.8 0.1 3.0 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KUM65489.1 - 0.0056 16.9 0.0 0.017 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KUM65489.1 - 0.0065 16.5 0.3 0.07 13.2 0.2 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KUM65489.1 - 0.0067 17.0 0.1 0.018 15.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 KUM65489.1 - 0.007 16.6 0.1 0.016 15.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KUM65489.1 - 0.0083 15.8 0.1 0.027 14.1 0.1 1.9 1 0 0 1 1 1 1 Thymidylate kinase MobB PF03205.14 KUM65489.1 - 0.0099 15.8 0.0 0.032 14.1 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.6 KUM65489.1 - 0.03 14.2 0.4 0.25 11.2 0.3 2.2 1 1 0 1 1 1 0 AAA domain MipZ PF09140.11 KUM65489.1 - 0.038 13.3 0.6 0.69 9.1 0.6 2.3 1 1 0 1 1 1 0 ATPase MipZ Arf PF00025.21 KUM65489.1 - 0.085 12.3 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 1 0 ADP-ribosylation factor family AAA_24 PF13479.6 KUM65489.1 - 0.097 12.4 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KUM65489.1 - 0.098 13.2 0.8 0.49 10.9 0.0 2.3 2 1 0 2 2 2 0 ABC transporter GET2 PF08690.10 KUM65489.1 - 0.77 9.4 5.6 1.4 8.5 5.6 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 Mito_carr PF00153.27 KUM65490.1 - 1.9e-10 40.5 6.0 0.006 16.5 0.0 4.9 3 2 0 3 3 3 3 Mitochondrial carrier protein Fer2 PF00111.27 KUM65491.1 - 6.9e-14 51.6 0.7 9.9e-14 51.1 0.7 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Adenyl_transf PF04439.12 KUM65491.1 - 0.14 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Streptomycin adenylyltransferase PhoD PF09423.10 KUM65492.1 - 5.8e-37 127.5 0.0 1.3e-36 126.4 0.0 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 KUM65492.1 - 0.0018 18.8 0.3 0.005 17.4 0.3 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain DUF4819 PF16090.5 KUM65492.1 - 0.013 15.5 0.1 0.055 13.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4819) Glyco_hydro_18 PF00704.28 KUM65494.1 - 9.7e-15 55.1 0.0 1.6e-14 54.4 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Internalin_N PF12354.8 KUM65496.1 - 0.083 13.0 2.8 5.6 7.1 0.1 3.6 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal APG6_N PF17675.1 KUM65497.1 - 0.00036 21.1 2.1 0.00036 21.1 2.1 6.5 3 2 3 6 6 6 1 Apg6 coiled-coil region Fez1 PF06818.15 KUM65497.1 - 0.0028 18.1 15.3 0.0028 18.1 15.3 4.6 3 1 1 4 4 4 2 Fez1 TMF_DNA_bd PF12329.8 KUM65497.1 - 0.0069 16.4 4.8 0.0069 16.4 4.8 8.3 4 2 4 9 9 9 2 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 KUM65497.1 - 0.013 15.3 5.9 0.013 15.3 5.9 8.6 4 4 5 9 9 9 0 Septum formation initiator PKcGMP_CC PF16808.5 KUM65497.1 - 0.057 13.3 26.0 3.2 7.7 2.1 7.6 6 1 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GAS PF13851.6 KUM65497.1 - 8.4 5.7 74.3 0.3 10.4 7.4 5.6 3 2 2 5 5 5 0 Growth-arrest specific micro-tubule binding UBA PF00627.31 KUM65498.1 - 5.9e-05 22.9 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.17 KUM65498.1 - 7.7e-05 22.5 0.7 0.57 10.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KUM65498.1 - 0.0006 19.5 0.1 8.4 6.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KUM65498.1 - 0.01 16.1 0.2 0.072 13.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.31 KUM65498.1 - 0.098 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 DnaJ domain GCD14 PF08704.10 KUM65499.1 - 1.3e-59 201.8 0.1 4.4e-59 200.1 0.0 1.9 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit AdoHcyase PF05221.17 KUM65499.1 - 0.032 13.4 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase SGS PF05002.15 KUM65500.1 - 3.7e-28 97.4 0.8 9.5e-28 96.1 0.8 1.7 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KUM65500.1 - 4.8e-16 59.5 0.2 8e-16 58.8 0.2 1.4 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 KUM65500.1 - 0.56 10.1 5.0 5.4 7.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KUM65500.1 - 1.2 9.4 8.5 8.8 6.7 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KUM65500.1 - 7.7 6.9 7.8 5.6 7.3 2.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat SQHop_cyclase_C PF13243.6 KUM65501.1 - 2.5e-49 168.1 0.3 6.8e-47 160.1 0.4 2.6 2 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KUM65501.1 - 1.8e-45 155.3 2.3 1.4e-41 142.5 0.2 3.4 4 0 0 4 4 4 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KUM65501.1 - 3.6e-31 106.6 8.5 6.6e-10 38.6 0.5 4.5 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KUM65501.1 - 0.00059 19.3 0.2 0.98 8.7 0.0 3.6 2 1 2 4 4 4 2 Pectic acid lyase ABC2_membrane PF01061.24 KUM65502.1 - 9.8e-87 289.8 56.1 4.7e-47 160.1 24.0 3.3 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KUM65502.1 - 2.4e-38 131.8 0.0 2.1e-18 67.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KUM65502.1 - 5.7e-35 119.1 6.6 3.7e-33 113.3 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KUM65502.1 - 1e-18 67.7 0.1 1e-18 67.7 0.1 2.0 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KUM65502.1 - 1.7e-06 28.6 1.0 0.0015 19.0 0.1 2.8 3 0 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KUM65502.1 - 2.9e-06 27.3 0.2 0.0047 16.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 KUM65502.1 - 3.5e-06 26.8 0.1 3.7e-05 23.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KUM65502.1 - 0.00076 19.7 0.1 0.45 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KUM65502.1 - 0.00079 19.1 3.1 0.028 14.1 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KUM65502.1 - 0.00086 19.9 0.0 0.21 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KUM65502.1 - 0.0015 18.0 0.0 0.25 10.7 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KUM65502.1 - 0.0017 18.3 2.0 3.2 7.7 0.1 3.4 3 0 0 3 3 3 2 NACHT domain dNK PF01712.19 KUM65502.1 - 0.0034 17.3 0.0 0.81 9.5 0.0 2.4 2 0 0 2 2 2 1 Deoxynucleoside kinase ABC2_membrane_3 PF12698.7 KUM65502.1 - 0.0063 15.7 44.0 0.063 12.4 19.4 3.2 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 KUM65502.1 - 0.0072 16.2 0.1 5.2 6.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KUM65502.1 - 0.011 16.2 3.7 0.61 10.5 0.0 3.4 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KUM65502.1 - 0.017 14.7 0.9 0.41 10.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KUM65502.1 - 0.03 14.1 0.4 3.6 7.3 0.2 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KUM65502.1 - 0.063 13.0 0.5 4.4 7.0 0.0 2.6 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 KUM65502.1 - 0.066 13.3 0.3 24 5.1 0.1 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KUM65502.1 - 0.081 12.6 0.1 4.8 6.9 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_28 PF13521.6 KUM65502.1 - 0.09 13.0 0.3 3.2 8.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KUM65502.1 - 0.13 12.6 4.1 1.2 9.4 0.2 3.3 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 KUM65502.1 - 0.19 12.1 3.4 9.2 6.7 0.0 3.4 4 0 0 4 4 3 0 AAA domain Asp PF00026.23 KUM65503.1 - 2.3e-42 145.5 1.2 3e-42 145.1 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KUM65503.1 - 8.6e-06 26.3 0.6 0.15 12.8 0.0 4.5 4 1 0 4 4 4 1 Aspartyl protease gag-asp_proteas PF13975.6 KUM65503.1 - 6.6e-05 23.4 5.5 0.32 11.6 0.7 4.5 3 2 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 KUM65503.1 - 0.0012 19.1 4.2 0.0099 16.1 0.8 3.0 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KUM65503.1 - 0.0049 16.7 0.0 0.021 14.6 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal CTV_P33 PF07184.11 KUM65504.1 - 0.031 13.3 0.1 0.047 12.8 0.1 1.2 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein p450 PF00067.22 KUM65505.1 - 4.2e-48 164.3 0.0 5.6e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 KUM65506.1 - 1.5e-65 221.7 48.2 1.9e-65 221.4 48.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM65506.1 - 3e-13 49.2 42.8 4e-13 48.8 42.8 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 KUM65507.1 - 3.9e-20 72.1 29.4 3.9e-20 72.1 29.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CENP-B_N PF04218.13 KUM65507.1 - 0.16 11.6 0.2 0.35 10.6 0.2 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain adh_short PF00106.25 KUM65508.1 - 6.2e-20 71.5 0.0 7.8e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM65508.1 - 1.1e-11 44.8 0.0 1.3e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KUM65508.1 - 0.0072 15.7 0.1 0.0098 15.3 0.1 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Ribonuc_L-PSP PF01042.21 KUM65509.1 - 1.5e-28 99.3 0.1 1.6e-28 99.2 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DsbB PF02600.16 KUM65509.1 - 0.069 13.6 0.0 0.097 13.1 0.0 1.2 1 0 0 1 1 1 0 Disulfide bond formation protein DsbB Abhydrolase_3 PF07859.13 KUM65510.1 - 2.5e-64 217.0 0.0 3.2e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KUM65510.1 - 2.2e-10 40.4 0.0 3.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KUM65510.1 - 1.8e-07 30.4 0.0 3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KUM65510.1 - 0.00013 21.0 0.0 0.00041 19.3 0.0 1.8 2 1 0 2 2 2 1 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 KUM65510.1 - 0.0058 15.6 0.0 0.0084 15.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Glyco_hydro_43 PF04616.14 KUM65511.1 - 8.9e-57 192.6 5.6 1.1e-56 192.2 5.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KUM65511.1 - 1.8e-14 53.9 0.0 3.1e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_32N PF00251.20 KUM65511.1 - 0.011 15.4 0.0 0.88 9.1 0.3 2.4 1 1 1 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain tRNA-synt_1e PF01406.19 KUM65512.1 - 1.2e-113 379.5 0.0 2.2e-113 378.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KUM65512.1 - 9.3e-07 27.9 0.6 0.0097 14.7 0.1 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 KUM65512.1 - 0.0011 19.4 0.1 0.0011 19.4 0.1 2.2 2 0 0 2 2 2 1 DALR domain TAL_FSA PF00923.19 KUM65513.1 - 4e-46 157.6 0.1 5e-46 157.3 0.1 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase PQ-loop PF04193.14 KUM65514.1 - 4.5e-40 135.2 12.0 8.5e-21 73.5 1.8 2.7 2 0 0 2 2 2 2 PQ loop repeat Cas9-BH PF16593.5 KUM65514.1 - 0.078 12.7 5.3 0.16 11.7 5.3 1.5 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 HTH_Bact PF18768.1 KUM65514.1 - 0.17 11.5 1.0 0.36 10.4 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix bacterial domain MSA-2c PF12238.8 KUM65514.1 - 0.44 10.5 1.5 0.67 9.9 1.5 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF2157 PF09925.9 KUM65514.1 - 1.2 8.9 4.9 6.3 6.6 1.1 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) zf-HYPF PF07503.12 KUM65516.1 - 0.033 14.0 0.1 0.066 13.0 0.1 1.5 1 0 0 1 1 1 0 HypF finger TP6A_N PF04406.14 KUM65517.1 - 3.2e-11 43.1 0.3 6e-11 42.2 0.3 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase tRNA_int_endo PF01974.17 KUM65519.1 - 1.9e-18 66.3 0.9 1e-17 64.0 0.9 2.0 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KUM65519.1 - 1.9e-05 24.2 0.0 0.011 15.4 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain MMR1 PF08505.10 KUM65519.1 - 2.2 8.5 11.4 3.3 7.9 11.4 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF1688 PF07958.11 KUM65520.1 - 2.2e-181 603.2 0.0 2.5e-181 603.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Gtr1_RagA PF04670.12 KUM65521.1 - 9.4e-95 316.4 0.4 1.1e-94 316.1 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KUM65521.1 - 6.8e-09 36.0 0.0 1.4e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM65521.1 - 3e-08 33.3 0.0 4.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KUM65521.1 - 3.8e-08 33.1 0.0 5.7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KUM65521.1 - 3.8e-07 30.2 0.0 6.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KUM65521.1 - 0.00079 18.7 2.0 0.64 9.1 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 KUM65521.1 - 0.0012 18.9 0.1 0.0026 17.8 0.1 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain DUF815 PF05673.13 KUM65521.1 - 0.0095 15.1 0.1 0.019 14.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 KUM65521.1 - 0.012 15.3 0.3 0.058 13.1 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KUM65521.1 - 0.018 15.5 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KUM65521.1 - 0.043 13.7 0.3 0.37 10.7 0.0 2.5 3 0 0 3 3 3 0 RsgA GTPase AAA_7 PF12775.7 KUM65521.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AIG1 PF04548.16 KUM65521.1 - 0.34 10.2 1.4 0.45 9.8 0.4 1.9 2 1 0 2 2 2 0 AIG1 family Myb_DNA-binding PF00249.31 KUM65522.1 - 0.0081 16.3 0.0 0.87 9.8 0.1 3.3 2 1 1 3 3 3 1 Myb-like DNA-binding domain 4HB_MCP_1 PF12729.7 KUM65522.1 - 0.098 12.2 0.4 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF3995 PF13160.6 KUM65522.1 - 1.1 9.6 9.1 6.3 7.2 1.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) Peptidase_M18 PF02127.15 KUM65523.1 - 6.7e-137 456.8 0.0 7.6e-137 456.6 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KUM65523.1 - 0.038 13.0 0.0 1.2 8.1 0.0 2.4 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Nop10p PF04135.12 KUM65524.1 - 4e-21 74.8 0.6 4e-21 74.8 0.6 1.7 2 0 0 2 2 2 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.11 KUM65525.1 - 3.6e-30 103.9 4.1 6.6e-30 103.1 4.1 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KUM65525.1 - 4.5e-30 104.0 0.3 1.3e-29 102.5 0.0 2.0 2 0 0 2 2 2 1 PIN domain of ribonuclease zinc_ribbon_15 PF17032.5 KUM65525.1 - 0.026 15.3 0.5 0.055 14.2 0.5 1.5 1 0 0 1 1 1 0 zinc-ribbon family zf-NADH-PPase PF09297.11 KUM65525.1 - 0.074 12.7 1.6 0.33 10.6 0.3 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain ADH_N PF08240.12 KUM65526.1 - 4.6e-28 97.3 1.7 1.1e-27 96.0 1.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM65526.1 - 2.9e-07 30.5 0.1 0.00091 19.2 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KUM65526.1 - 0.00011 22.0 2.5 0.00014 21.7 0.5 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 KUM65526.1 - 0.0079 15.7 0.2 0.062 12.8 0.0 2.1 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Hap4_Hap_bind PF10297.9 KUM65527.1 - 2.8e-08 33.6 6.7 2.8e-08 33.6 6.7 2.8 3 0 0 3 3 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KUM65527.1 - 2.4e-07 30.7 7.3 7.3e-06 26.0 8.8 2.1 1 1 1 2 2 2 1 bZIP transcription factor Striatin PF08232.12 KUM65527.1 - 0.01 16.4 0.2 0.024 15.2 0.1 1.7 1 1 0 1 1 1 0 Striatin family DUF812 PF05667.11 KUM65527.1 - 0.014 14.3 1.0 0.02 13.8 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Filament PF00038.21 KUM65527.1 - 0.042 13.4 2.3 0.071 12.7 2.3 1.4 1 0 0 1 1 1 0 Intermediate filament protein Tropomyosin_1 PF12718.7 KUM65527.1 - 0.07 13.3 1.7 0.12 12.5 1.7 1.3 1 0 0 1 1 1 0 Tropomyosin like Tmemb_cc2 PF10267.9 KUM65527.1 - 0.095 11.8 0.2 0.16 11.1 0.2 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein dsrm PF00035.26 KUM65527.1 - 0.13 13.0 0.0 0.33 11.7 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif DUF2353 PF09789.9 KUM65527.1 - 0.17 11.2 1.9 0.25 10.7 1.9 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) bZIP_2 PF07716.15 KUM65527.1 - 0.17 12.0 9.8 0.4 10.8 9.4 1.8 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.17 KUM65527.1 - 2 9.0 7.7 0.087 13.4 1.5 2.0 2 0 0 2 2 1 0 bZIP Maf transcription factor Scramblase PF03803.15 KUM65528.1 - 2.2e-50 171.0 1.4 9.5e-24 83.9 0.1 3.0 2 1 0 2 2 2 2 Scramblase UQ_con PF00179.26 KUM65529.1 - 7.4e-50 168.2 0.0 8.4e-50 168.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AAA_12 PF13087.6 KUM65530.1 - 3.2e-37 128.1 0.0 5.6e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KUM65530.1 - 3.9e-18 66.2 0.9 2e-17 63.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KUM65530.1 - 4.7e-09 36.3 0.0 0.00016 21.5 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KUM65530.1 - 9.3e-06 25.4 0.0 2.7e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 KUM65530.1 - 0.0051 16.2 0.3 0.2 11.0 0.0 2.2 1 1 0 2 2 2 1 UvrD-like helicase C-terminal domain Rad9_Rad53_bind PF08605.10 KUM65532.1 - 1.7e-29 102.6 0.0 2.8e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding Tudor_3 PF18115.1 KUM65532.1 - 1.1e-18 66.7 0.1 2.3e-18 65.7 0.1 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain BRCT_2 PF16589.5 KUM65532.1 - 2.9e-08 34.0 0.0 1.8e-07 31.5 0.0 2.4 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KUM65532.1 - 1.5e-06 28.5 0.0 5.3e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KUM65532.1 - 0.001 18.9 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Ysc84 PF04366.12 KUM65533.1 - 7.3e-38 129.2 1.1 1.1e-37 128.6 1.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator GMC_oxred_C PF05199.13 KUM65534.1 - 1.8e-43 148.5 0.1 4e-43 147.4 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KUM65534.1 - 1.2e-41 143.1 0.0 3e-34 118.8 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 KUM65534.1 - 7.6e-07 28.6 0.0 2.1e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM65534.1 - 4e-06 26.2 0.3 1.8e-05 24.0 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KUM65534.1 - 1.6e-05 24.7 0.0 0.0012 18.5 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KUM65534.1 - 1.9e-05 24.8 0.6 5.8e-05 23.2 0.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KUM65534.1 - 0.0005 19.3 0.4 0.0018 17.4 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KUM65534.1 - 0.0016 17.5 0.1 0.0027 16.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KUM65534.1 - 0.0031 16.3 0.1 0.014 14.1 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KUM65534.1 - 0.0031 16.8 0.1 2.2 7.4 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KUM65534.1 - 0.014 14.7 0.1 0.026 13.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KUM65534.1 - 0.031 13.6 0.6 0.058 12.7 0.6 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KUM65534.1 - 0.084 13.4 2.1 6.8 7.3 0.2 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KUM65534.1 - 0.13 12.2 0.2 0.27 11.1 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 KUM65534.1 - 0.19 10.5 0.3 0.28 10.0 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Ribosomal_L27 PF01016.19 KUM65535.1 - 3.4e-28 97.5 0.1 5.9e-28 96.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein GFO_IDH_MocA PF01408.22 KUM65539.1 - 1.8e-18 67.5 0.1 2.9e-18 66.8 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KUM65539.1 - 0.096 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_18 PF00704.28 KUM65540.1 - 1.6e-46 159.5 8.1 3.3e-46 158.5 8.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KUM65540.1 - 1.8e-06 27.9 0.0 0.0041 17.2 0.0 3.3 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.19 KUM65540.1 - 3.9e-05 24.0 7.3 3.9e-05 24.0 7.3 4.8 4 1 0 4 4 4 1 Chitin recognition protein SseC PF04888.12 KUM65540.1 - 0.47 10.0 7.6 1.1 8.8 7.6 1.6 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family Ank_2 PF12796.7 KUM65541.1 - 7.8e-21 74.5 2.8 2.2e-08 34.6 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KUM65541.1 - 3.2e-13 48.6 0.5 0.063 13.9 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 KUM65541.1 - 6.1e-13 49.0 0.1 0.00035 21.1 0.0 4.4 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM65541.1 - 3.5e-11 43.1 0.7 0.096 13.0 0.1 5.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KUM65541.1 - 3.7e-06 27.1 0.5 8 7.1 0.0 5.1 5 1 0 5 5 5 2 Ankyrin repeat DUF3081 PF11280.8 KUM65541.1 - 0.063 13.1 0.1 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) Marek_SORF3 PF07153.11 KUM65541.1 - 0.1 11.9 0.1 0.89 8.8 0.0 2.0 2 0 0 2 2 2 0 Marek's disease-like virus SORF3 protein DUF1593 PF07632.11 KUM65542.1 - 1.2e-88 296.9 0.7 1.9e-88 296.2 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1593) FAD_binding_3 PF01494.19 KUM65543.1 - 3e-07 30.0 0.0 3.2e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KUM65543.1 - 0.016 14.3 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase Ank_5 PF13857.6 KUM65544.1 - 5.1e-20 71.3 0.4 0.00042 20.6 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KUM65544.1 - 3.8e-16 59.2 0.2 1.6 9.4 0.0 9.1 8 2 0 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 KUM65544.1 - 6.9e-14 51.6 0.1 0.062 13.8 0.0 7.6 8 1 0 8 8 8 4 Ankyrin repeat Ank_2 PF12796.7 KUM65544.1 - 6.8e-10 39.4 0.0 0.97 10.1 0.0 6.4 4 2 2 7 7 7 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KUM65544.1 - 2.5e-08 33.5 4.7 30 5.6 0.0 10.3 11 2 0 11 11 11 1 Ankyrin repeat MFS_1 PF07690.16 KUM65545.1 - 6.4e-27 94.4 40.3 1.6e-25 89.8 23.7 2.7 1 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM65545.1 - 0.0014 17.6 19.8 0.018 13.9 19.3 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1751 PF08551.10 KUM65545.1 - 0.88 10.2 9.5 0.038 14.6 2.6 2.3 2 1 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) NUC194 PF08163.12 KUM65546.1 - 0.059 12.3 0.0 0.072 12.0 0.0 1.0 1 0 0 1 1 1 0 NUC194 domain zf-CCCH PF00642.24 KUM65547.1 - 3.8e-09 36.2 1.4 7.2e-09 35.4 1.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KUM65547.1 - 4.6e-07 29.6 5.7 8.6e-07 28.7 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KUM65547.1 - 7.3e-07 29.1 8.6 1.2e-06 28.3 8.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KUM65547.1 - 8.8e-07 28.8 6.7 1.7e-06 27.9 6.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KUM65547.1 - 1.9e-06 27.6 8.6 3.4e-06 26.8 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KUM65547.1 - 3.6e-06 27.0 2.6 7.6e-06 26.0 2.6 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf_CCCH_4 PF18345.1 KUM65547.1 - 3.7e-06 26.8 5.4 7.1e-06 25.9 5.4 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4 PF00097.25 KUM65547.1 - 6.4e-06 25.9 9.9 1.1e-05 25.2 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KUM65547.1 - 2.7e-05 24.4 7.2 5.6e-05 23.4 7.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 KUM65547.1 - 0.00088 19.0 1.2 0.00088 19.0 1.2 1.7 2 0 0 2 2 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 KUM65547.1 - 0.0016 18.2 6.0 0.0031 17.3 6.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KUM65547.1 - 0.0098 16.0 8.3 0.019 15.1 8.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.6 KUM65547.1 - 0.1 13.1 1.6 0.23 12.0 1.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-Nse PF11789.8 KUM65547.1 - 0.36 10.7 2.7 0.72 9.7 2.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 KUM65547.1 - 0.68 10.3 4.2 1.7 9.0 4.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Mcp5_PH PF12814.7 KUM65548.1 - 7.6e-45 152.0 0.2 2.1e-44 150.6 0.2 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KUM65548.1 - 4.6e-07 30.3 0.0 1.4e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 PH domain TTC5_OB PF16669.5 KUM65548.1 - 2.9 7.6 5.9 3.2e+02 1.0 5.9 3.3 1 1 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain ERM PF00769.19 KUM65548.1 - 4.6 7.0 46.6 0.41 10.4 0.8 4.0 4 0 0 4 4 4 0 Ezrin/radixin/moesin family Methyltransf_23 PF13489.6 KUM65549.1 - 1e-13 51.5 0.0 1.5e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM65549.1 - 3.3e-09 37.3 0.0 7.7e-09 36.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM65549.1 - 4.2e-05 24.2 0.0 0.00013 22.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM65549.1 - 0.00012 22.7 0.0 0.0078 16.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM65549.1 - 0.0056 16.5 0.0 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KUM65549.1 - 0.027 13.7 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Ku PF02735.16 KUM65550.1 - 6.5e-43 146.8 0.0 2.5e-42 144.9 0.0 1.9 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KUM65550.1 - 2.3e-33 115.8 0.0 3.4e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KUM65550.1 - 1.6e-25 89.6 0.3 5.6e-25 87.9 0.2 2.0 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KUM65550.1 - 4.8e-10 39.0 0.0 9.8e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.6 KUM65550.1 - 0.048 14.3 0.0 0.41 11.3 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain HeH PF12949.7 KUM65550.1 - 0.13 12.0 0.5 0.67 9.7 0.5 2.1 1 1 0 1 1 1 0 HeH/LEM domain VWA PF00092.28 KUM65550.1 - 0.15 12.3 0.0 0.97 9.7 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain Fungal_trans PF04082.18 KUM65551.1 - 5.6e-14 51.8 0.5 9.8e-14 51.0 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KUM65552.1 - 2.5e-70 237.5 0.0 1.8e-69 234.7 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KUM65552.1 - 9e-32 110.4 0.0 1.6e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KUM65552.1 - 0.011 14.9 0.0 0.052 12.8 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM65552.1 - 0.055 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KUM65552.1 - 0.072 12.1 0.4 0.25 10.3 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein SE PF08491.10 KUM65552.1 - 0.092 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.14 KUM65552.1 - 0.1 11.3 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF1834 PF08873.11 KUM65552.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) DUF3431 PF11913.8 KUM65553.1 - 1e-76 257.5 0.5 1.2e-76 257.2 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Ferrochelatase PF00762.19 KUM65554.1 - 6.2e-47 160.2 0.0 7.9e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase MP PF01107.18 KUM65554.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Viral movement protein (MP) Exo_endo_phos PF03372.23 KUM65555.1 - 1.5e-08 34.4 0.0 2.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LIDHydrolase PF10230.9 KUM65557.1 - 6e-82 275.2 0.0 6.8e-82 275.0 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KUM65557.1 - 1.5e-05 25.7 0.1 1.7e-05 25.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM65557.1 - 0.0016 17.8 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KUM65557.1 - 0.0033 17.3 0.0 0.01 15.7 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KUM65557.1 - 0.0065 16.1 0.0 0.02 14.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 KUM65557.1 - 0.011 14.9 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 KUM65557.1 - 0.022 13.8 0.0 0.063 12.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Thioesterase PF00975.20 KUM65557.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 KUM65557.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 KUM65557.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DCP1 PF06058.13 KUM65558.1 - 3.4e-29 101.1 0.0 5.5e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family SLC35F PF06027.12 KUM65559.1 - 7.9e-100 334.2 22.0 9.5e-100 334.0 22.0 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 KUM65559.1 - 3.5e-10 40.2 27.9 5.3e-05 23.4 8.8 2.3 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 KUM65559.1 - 6.1e-10 38.6 2.1 1e-09 37.8 2.1 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like DUF5115 PF17142.4 KUM65559.1 - 0.14 11.8 0.2 0.19 11.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5115) DUF2516 PF10724.9 KUM65559.1 - 2.8 8.3 10.7 7.6 6.9 2.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) DUF2628 PF10947.8 KUM65559.1 - 6.4 7.2 11.2 0.78 10.1 3.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) SMK-1 PF04802.15 KUM65560.1 - 1.4e-77 259.9 0.1 2.8e-77 258.9 0.1 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 PAP_assoc PF03828.19 KUM65561.1 - 1e-19 70.5 0.1 2.5e-19 69.3 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KUM65561.1 - 0.00035 20.8 0.0 0.00069 19.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KUM65561.1 - 0.02 15.0 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase CALM_bind PF16025.5 KUM65562.1 - 0.12 12.9 6.0 0.22 12.0 6.0 1.4 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding PPR PF01535.20 KUM65563.1 - 0.011 16.0 0.7 6.7 7.2 0.0 4.0 4 0 0 4 4 4 0 PPR repeat TPR_19 PF14559.6 KUM65563.1 - 0.03 14.8 0.0 10 6.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat USP8_interact PF08941.10 KUM65563.1 - 0.051 13.4 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 USP8 interacting PPR_long PF17177.4 KUM65563.1 - 0.064 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP SE PF08491.10 KUM65564.1 - 1e-96 323.3 0.0 1.3e-96 322.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KUM65564.1 - 1.3e-12 47.6 0.0 2.3e-06 27.1 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KUM65564.1 - 1.1e-06 28.5 0.2 1.5e-05 24.8 0.3 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KUM65564.1 - 0.00053 19.2 1.0 0.00082 18.6 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KUM65564.1 - 0.00059 19.2 0.5 0.0013 18.1 0.1 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KUM65564.1 - 0.00095 19.4 0.9 0.002 18.3 0.9 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KUM65564.1 - 0.0011 18.2 0.1 0.022 13.8 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KUM65564.1 - 0.0015 18.0 0.4 0.0023 17.3 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KUM65564.1 - 0.0029 18.1 0.4 0.033 14.7 0.5 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KUM65564.1 - 0.0036 16.4 0.5 0.0076 15.3 0.5 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KUM65564.1 - 0.0043 16.3 0.2 0.0071 15.6 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KUM65564.1 - 0.014 15.1 0.3 0.023 14.3 0.3 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KUM65564.1 - 0.033 12.9 0.3 0.054 12.2 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.20 KUM65564.1 - 0.056 13.5 0.0 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KUM65564.1 - 0.058 12.7 0.4 0.099 12.0 0.4 1.3 1 0 0 1 1 1 0 ThiF family Trp_halogenase PF04820.14 KUM65564.1 - 0.068 12.0 0.1 0.43 9.4 0.1 1.9 2 0 0 2 2 2 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.23 KUM65564.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.6 KUM65564.1 - 0.29 10.3 0.4 0.52 9.5 0.4 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.13 KUM65565.1 - 2.1e-10 40.6 0.0 3.2e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KUM65565.1 - 5.2e-07 29.7 0.0 2.1e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Glyco_hydro_3_C PF01915.22 KUM65566.1 - 9.5e-53 179.2 0.1 1.5e-52 178.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KUM65566.1 - 4.3e-35 121.6 0.1 1.5e-34 119.8 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KUM65566.1 - 7.2e-25 86.9 0.0 1.5e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Alpha-amylase PF00128.24 KUM65567.1 - 7.7e-16 58.6 3.3 2.6e-15 56.8 2.2 2.3 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KUM65567.1 - 4.3e-14 52.8 0.1 7.6e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KUM65567.1 - 1.8e-05 24.3 0.0 3.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 SH3_9 PF14604.6 KUM65568.1 - 3.3e-16 58.9 0.1 5.6e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KUM65568.1 - 1.3e-13 50.3 0.1 2.2e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KUM65568.1 - 1.3e-09 37.6 0.0 2.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 KUM65568.1 - 2.3e-08 34.0 0.4 3.5e-08 33.4 0.4 1.2 1 0 0 1 1 1 1 BAR domain Apolipoprotein PF01442.18 KUM65568.1 - 0.03 14.2 0.7 0.1 12.5 1.0 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain MFS_1 PF07690.16 KUM65569.1 - 5.4e-42 144.0 46.9 1.4e-41 142.6 46.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM65569.1 - 3.5e-13 49.2 6.8 3.5e-13 49.2 6.8 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter FAD_binding_3 PF01494.19 KUM65570.1 - 3.9e-21 75.7 2.9 9e-20 71.2 2.9 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KUM65570.1 - 3.9e-09 36.6 0.0 6.5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KUM65570.1 - 0.00026 21.1 0.3 0.00086 19.5 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KUM65570.1 - 0.00097 19.7 1.6 0.0012 19.4 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM65570.1 - 0.0021 17.3 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KUM65570.1 - 0.0043 16.2 0.0 0.22 10.5 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase HI0933_like PF03486.14 KUM65570.1 - 0.015 14.0 0.3 0.021 13.5 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 KUM65570.1 - 0.022 14.6 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KUM65570.1 - 0.022 14.1 1.2 0.04 13.3 1.2 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KUM65570.1 - 0.066 12.3 0.1 0.13 11.3 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KUM65570.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KUM65570.1 - 0.16 11.2 0.1 0.32 10.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KUM65570.1 - 0.16 11.9 0.3 0.47 10.4 0.3 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KUM65570.1 - 0.2 10.9 1.8 22 4.2 0.0 3.1 3 1 0 3 3 3 0 Flavin containing amine oxidoreductase ketoacyl-synt PF00109.26 KUM65571.1 - 9.4e-65 218.7 0.2 9.4e-65 218.7 0.2 2.0 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 KUM65571.1 - 1.4e-25 90.0 0.0 2.2e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 KUM65571.1 - 6.6e-25 88.3 0.4 1.7e-24 86.9 0.2 1.8 2 0 0 2 2 2 1 Acyl transferase domain HTH_51 PF18558.1 KUM65571.1 - 3.6e-21 74.8 0.4 2.5e-20 72.1 0.0 2.7 4 0 0 4 4 3 1 Helix-turn-helix domain PS-DH PF14765.6 KUM65571.1 - 2.8e-13 49.8 0.0 4.9e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KUM65571.1 - 8.9e-13 48.3 0.0 2.6e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KUM65571.1 - 1.2e-11 45.2 0.0 4.3e-11 43.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KUM65571.1 - 4.8e-11 42.9 0.1 1.3e-10 41.5 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 KUM65571.1 - 2.2e-10 41.1 0.0 8e-10 39.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM65571.1 - 3.6e-08 33.3 0.0 8.4e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM65571.1 - 4e-08 33.3 0.0 1.1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM65571.1 - 3.6e-07 30.8 0.0 1.3e-06 28.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KUM65571.1 - 6.1e-05 22.6 0.0 0.00027 20.5 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 KUM65571.1 - 0.00013 21.4 0.1 0.00035 20.0 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KUM65571.1 - 0.024 15.1 0.0 0.074 13.5 0.0 1.9 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Methyltransf_33 PF10017.9 KUM65571.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Polysacc_synt_2 PF02719.15 KUM65571.1 - 0.11 11.6 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HSP20 PF00011.21 KUM65572.1 - 3.6e-17 62.4 0.1 4.9e-17 61.9 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KUM65572.1 - 3.5e-06 26.5 0.0 9.3e-06 25.1 0.0 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Peptidase_S9 PF00326.21 KUM65573.1 - 1.5e-40 138.9 0.0 2.5e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KUM65573.1 - 1.2e-10 41.4 0.1 4.2e-10 39.6 0.1 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KUM65573.1 - 5.8e-07 29.6 0.0 0.002 18.1 0.0 2.4 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 KUM65573.1 - 6.9e-07 29.3 0.0 1.9e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 KUM65573.1 - 1.5e-06 27.7 0.2 0.0018 17.6 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 KUM65573.1 - 3e-06 27.1 0.0 7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 KUM65573.1 - 3.3e-06 26.9 0.1 0.042 13.4 0.3 2.6 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) COesterase PF00135.28 KUM65573.1 - 6.4e-05 22.0 0.2 0.00011 21.3 0.2 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.20 KUM65573.1 - 6.8e-05 22.6 1.4 0.28 10.8 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 KUM65573.1 - 0.00039 20.1 0.0 0.00063 19.5 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 KUM65573.1 - 0.00091 19.1 0.4 0.011 15.6 0.4 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold PD40 PF07676.12 KUM65573.1 - 0.0073 16.2 1.1 2.7 8.0 0.1 2.6 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Abhydrolase_2 PF02230.16 KUM65573.1 - 0.025 14.4 0.1 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 KUM65573.1 - 0.038 13.5 0.6 7.2 6.0 0.6 2.5 2 1 0 2 2 2 0 Esterase PHB depolymerase OLF PF02191.16 KUM65573.1 - 0.086 12.4 0.0 0.49 9.9 0.0 1.9 2 0 0 2 2 2 0 Olfactomedin-like domain DUF2439 PF10382.9 KUM65574.1 - 7.4e-29 99.9 0.5 1.2e-28 99.3 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Fungal_trans PF04082.18 KUM65575.1 - 7.9e-10 38.2 2.3 1.3e-09 37.4 1.9 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.12 KUM65576.1 - 6.1e-09 35.7 0.0 3.1e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM65576.1 - 6.8e-07 29.3 0.1 1.3e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2001 PF09393.10 KUM65576.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube protein MFS_1 PF07690.16 KUM65577.1 - 1.9e-39 135.6 30.5 3.1e-39 134.9 30.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM65577.1 - 1.9e-12 46.8 5.9 1.9e-12 46.8 5.9 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter FAD_binding_3 PF01494.19 KUM65579.1 - 2.7e-79 267.0 0.0 7.7e-57 193.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.12 KUM65579.1 - 1.9e-37 128.9 0.0 3.2e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KUM65579.1 - 0.0002 20.2 0.1 0.0003 19.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KUM65579.1 - 0.00027 20.2 0.0 0.00045 19.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KUM65579.1 - 0.0007 18.9 0.0 0.0067 15.7 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM65579.1 - 0.00076 18.7 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KUM65579.1 - 0.0025 18.0 0.0 0.0062 16.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KUM65579.1 - 0.0076 15.7 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KUM65579.1 - 0.0098 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KUM65579.1 - 0.012 15.2 0.2 0.042 13.4 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KUM65579.1 - 0.05 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM65579.1 - 0.051 12.8 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KUM65579.1 - 0.14 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MMR_HSR1_C PF08438.10 KUM65581.1 - 1.4e-36 125.4 0.0 2.4e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KUM65581.1 - 1.7e-20 73.2 0.0 4e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KUM65581.1 - 1.1e-08 34.7 0.1 1.7e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KUM65581.1 - 0.0034 17.0 0.0 0.71 9.4 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KUM65581.1 - 0.018 15.1 1.6 0.14 12.2 0.2 2.5 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 KUM65581.1 - 0.023 14.5 0.2 5 6.8 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ploopntkinase3 PF18751.1 KUM65581.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 KUM65581.1 - 0.11 13.0 0.0 0.6 10.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter KTI12 PF08433.10 KUM65581.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SET PF00856.28 KUM65583.1 - 0.008 16.6 0.0 0.021 15.2 0.0 1.7 2 0 0 2 2 2 1 SET domain PhaP_Bmeg PF09602.10 KUM65583.1 - 0.065 13.2 0.2 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Phasin_2 PF09361.10 KUM65583.1 - 2.2 8.6 6.0 4.4 7.6 0.1 2.8 3 0 0 3 3 3 0 Phasin protein Fungal_trans PF04082.18 KUM65584.1 - 1.4e-34 119.3 0.0 2.5e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM65584.1 - 1e-08 35.2 14.7 1.7e-08 34.4 14.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 KUM65584.1 - 0.048 13.8 0.1 0.15 12.2 0.1 1.8 1 0 0 1 1 1 0 bZIP transcription factor DUF3533 PF12051.8 KUM65585.1 - 5e-84 282.4 12.3 6.4e-84 282.0 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Nse5 PF08691.10 KUM65585.1 - 0.037 12.7 0.0 0.051 12.2 0.0 1.1 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 Sugar_tr PF00083.24 KUM65587.1 - 3.4e-135 451.4 23.1 3.9e-135 451.2 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM65587.1 - 1.7e-28 99.6 47.0 1e-21 77.3 22.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KUM65587.1 - 3.7e-06 25.8 23.4 1.9e-05 23.4 3.0 3.0 2 2 0 2 2 2 2 MFS/sugar transport protein UPF0715 PF17094.5 KUM65587.1 - 0.22 12.1 3.1 0.77 10.3 3.1 2.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0715) Pox_A14 PF05767.12 KUM65587.1 - 0.56 10.4 4.3 4.4 7.5 0.0 3.6 3 1 0 3 3 3 0 Poxvirus virion envelope protein A14 Spermine_synth PF01564.17 KUM65588.1 - 3.2e-73 245.2 0.0 4.4e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KUM65588.1 - 1.3e-23 82.6 0.1 2.2e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KUM65588.1 - 1.9e-05 25.3 0.0 5.1e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM65588.1 - 0.00016 22.3 0.2 0.0018 18.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KUM65588.1 - 0.037 13.6 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 KUM65588.1 - 0.098 12.6 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Band_7 PF01145.25 KUM65590.1 - 3.6e-24 85.7 8.4 8e-24 84.6 8.4 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KUM65590.1 - 0.00083 18.5 3.0 0.0011 18.1 3.0 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial PknG_rubred PF16919.5 KUM65590.1 - 0.15 12.2 0.2 0.27 11.4 0.2 1.3 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain UcrQ PF02939.16 KUM65591.1 - 1.6e-34 117.7 0.2 1.8e-34 117.5 0.2 1.1 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 KUM65591.1 - 0.11 12.9 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Fungal_trans PF04082.18 KUM65592.1 - 7.1e-16 58.0 0.7 1.3e-15 57.1 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain 3HCDH_N PF02737.18 KUM65593.1 - 7.7e-26 91.1 0.0 1.2e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KUM65593.1 - 9.1e-11 42.2 0.2 2.3e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KUM65593.1 - 0.025 14.7 0.0 0.06 13.5 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase FMN_dh PF01070.18 KUM65594.1 - 2.3e-115 385.3 0.0 2.6e-115 385.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KUM65594.1 - 0.00019 20.6 0.9 0.00031 19.9 0.5 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KUM65594.1 - 0.00038 19.7 0.1 0.00057 19.1 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KUM65594.1 - 0.0039 16.6 0.4 0.0057 16.1 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KUM65594.1 - 0.027 13.8 5.8 0.95 8.7 0.4 2.5 2 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KUM65594.1 - 0.063 12.7 0.3 0.64 9.4 0.2 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein Gpr1_Fun34_YaaH PF01184.19 KUM65595.1 - 5.6e-85 284.2 14.4 6.6e-85 283.9 14.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF202 PF02656.15 KUM65595.1 - 0.6 10.6 8.4 11 6.5 2.7 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF202) zf-C2H2_aberr PF17017.5 KUM65596.1 - 1.9e-07 31.4 0.4 1.9e-07 31.4 0.4 1.5 2 0 0 2 2 2 1 Aberrant zinc-finger zf-C2H2 PF00096.26 KUM65596.1 - 3.4e-05 24.0 16.5 0.41 11.2 3.7 3.9 3 1 0 3 3 3 3 Zinc finger, C2H2 type Cnn_1N PF07989.11 KUM65596.1 - 0.0015 18.7 0.2 0.013 15.6 0.1 2.2 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 Trimer_CC PF08954.11 KUM65596.1 - 0.038 13.5 5.0 0.088 12.4 5.0 1.5 1 0 0 1 1 1 0 Trimerisation motif zf-C2H2_4 PF13894.6 KUM65596.1 - 0.065 14.1 8.9 18 6.5 0.6 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger Transpos_assoc PF13963.6 KUM65596.1 - 0.11 12.8 0.3 0.11 12.8 0.3 2.1 1 1 0 2 2 2 0 Transposase-associated domain zf-H2C2_2 PF13465.6 KUM65596.1 - 9.6 6.8 15.3 5.7 7.6 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Methyltransf_34 PF11312.8 KUM65597.1 - 4.3e-101 338.2 0.0 5.8e-101 337.8 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase TPP_enzyme_N PF02776.18 KUM65598.1 - 1.6e-20 73.4 0.2 3e-20 72.5 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KUM65598.1 - 1.1e-11 44.6 0.0 2.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain adh_short PF00106.25 KUM65599.1 - 4.8e-28 97.9 0.1 7.1e-28 97.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM65599.1 - 2.2e-24 86.3 0.1 3.2e-24 85.8 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM65599.1 - 0.0065 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 KR domain FAM219A PF15260.6 KUM65600.1 - 0.061 13.7 0.1 0.067 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein family FAM219A JmjC PF02373.22 KUM65601.1 - 7.6e-39 132.7 2.4 8.5e-39 132.5 0.7 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KUM65601.1 - 1.2e-17 64.1 3.8 2.1e-17 63.2 3.8 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KUM65601.1 - 2.1e-17 63.2 3.9 5.8e-17 61.7 3.9 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.17 KUM65601.1 - 7.3e-16 57.8 0.2 2e-15 56.4 0.2 1.8 1 0 0 1 1 1 1 jmjN domain DUF2990 PF11693.8 KUM65602.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) p450 PF00067.22 KUM65603.1 - 3.4e-10 39.3 0.0 3.6e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 KUM65604.1 - 0.00018 21.5 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM65604.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain 4HBT_2 PF13279.6 KUM65605.1 - 1.4e-07 32.0 0.0 2.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily FAD_binding_4 PF01565.23 KUM65606.1 - 1.2e-16 60.8 2.5 2.6e-16 59.6 2.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KUM65606.1 - 3e-07 30.4 0.3 6e-07 29.5 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 KUM65607.1 - 2.5e-37 128.3 0.0 3.2e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM65607.1 - 1.8e-27 96.4 0.0 2.5e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM65607.1 - 9.4e-09 35.4 0.0 1.7e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KUM65607.1 - 0.00087 19.2 0.0 0.0025 17.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding CdhC PF03598.15 KUM65607.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit ERG4_ERG24 PF01222.17 KUM65608.1 - 3.8e-137 457.6 24.2 4.3e-137 457.4 24.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family OPT PF03169.15 KUM65609.1 - 1.9e-173 578.4 20.2 2.2e-173 578.2 20.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PAP2 PF01569.21 KUM65612.1 - 0.0064 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 PAP2 superfamily Ribosomal_L7Ae PF01248.26 KUM65613.1 - 8e-19 67.2 1.7 8e-19 67.2 1.7 2.6 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family D5_N PF08706.11 KUM65613.1 - 0.45 10.8 4.5 0.54 10.5 3.9 1.4 1 1 0 1 1 1 0 D5 N terminal like MAD PF05557.13 KUM65614.1 - 1.3e-58 199.0 74.9 1.1e-49 169.4 75.6 2.1 2 0 0 2 2 2 2 Mitotic checkpoint protein Flp_N PF03930.14 KUM65614.1 - 0.043 13.8 0.3 0.21 11.6 0.3 2.4 1 0 0 1 1 1 0 Recombinase Flp protein N-terminus Glyco_trans_1_3 PF13528.6 KUM65614.1 - 0.064 12.5 0.7 0.16 11.2 0.7 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF5320 PF17253.2 KUM65614.1 - 0.088 13.9 0.1 0.088 13.9 0.1 7.6 4 2 1 7 7 7 0 Family of unknown function (DUF5320) NAD_binding_10 PF13460.6 KUM65615.1 - 5.8e-15 55.7 0.0 8.4e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KUM65615.1 - 3.4e-14 53.0 0.0 4.7e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KUM65615.1 - 0.0013 18.3 0.0 0.0081 15.7 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KUM65615.1 - 0.031 14.3 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KUM65615.1 - 0.088 12.9 0.2 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 KUM65615.1 - 0.11 11.5 0.0 0.39 9.7 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Peptidase_C54 PF03416.19 KUM65615.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C54 Fungal_trans PF04082.18 KUM65616.1 - 0.0015 17.6 0.0 0.0018 17.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain muHD PF10291.9 KUM65617.1 - 5.3e-84 281.8 0.0 7.5e-84 281.3 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KUM65617.1 - 1.4e-07 31.6 0.1 7.6e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain COG2 PF06148.11 KUM65617.1 - 0.12 12.5 1.2 0.3 11.2 0.4 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Pkinase PF00069.25 KUM65618.1 - 1.6e-44 152.3 0.0 2.3e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM65618.1 - 4.2e-17 62.3 0.0 6.4e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KUM65618.1 - 1.4e-05 25.2 0.1 0.083 12.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KUM65618.1 - 5.3e-05 22.7 0.0 9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like KIX_2 PF16987.5 KUM65618.1 - 0.00041 20.3 0.5 0.00066 19.6 0.5 1.3 1 0 0 1 1 1 1 KIX domain Kdo PF06293.14 KUM65618.1 - 0.00094 18.6 0.0 0.012 14.9 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KUM65618.1 - 0.0011 17.8 0.0 0.0024 16.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KUM65618.1 - 0.084 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SH3_9 PF14604.6 KUM65619.1 - 3.3e-07 30.1 0.1 8.5e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KUM65619.1 - 9.9e-06 25.1 0.0 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain RIFIN PF02009.16 KUM65619.1 - 6.5e-05 23.0 0.5 0.00015 21.8 0.5 1.5 1 0 0 1 1 1 1 Rifin SH3_2 PF07653.17 KUM65619.1 - 0.00012 21.7 0.0 0.00053 19.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Amnionless PF14828.6 KUM65619.1 - 0.21 10.4 2.0 0.4 9.5 2.0 1.3 1 0 0 1 1 1 0 Amnionless LapA_dom PF06305.11 KUM65619.1 - 0.34 10.7 0.0 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RR_TM4-6 PF06459.12 KUM65619.1 - 5.3 6.8 9.2 8.6 6.1 9.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Macoilin PF09726.9 KUM65619.1 - 6.2 5.3 15.5 0.019 13.5 5.5 1.7 2 0 0 2 2 2 0 Macoilin family Sugar_tr PF00083.24 KUM65620.1 - 8.2e-110 367.7 13.9 1e-109 367.4 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM65620.1 - 4.9e-17 61.9 28.7 1.8e-13 50.2 5.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KUM65620.1 - 3.6e-07 28.9 1.7 3.6e-07 28.9 1.7 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family TPR_19 PF14559.6 KUM65620.1 - 0.21 12.1 0.0 0.56 10.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat AMP-binding PF00501.28 KUM65621.1 - 6.2e-91 305.1 0.0 7.9e-91 304.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KUM65621.1 - 7.4e-13 49.3 0.3 1.5e-12 48.3 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Use1 PF09753.9 KUM65622.1 - 1.2e-06 28.5 11.6 4.4e-06 26.6 11.6 2.0 1 1 0 1 1 1 1 Membrane fusion protein Use1 Syntaxin_2 PF14523.6 KUM65622.1 - 0.0086 16.4 3.9 1.4 9.3 0.1 2.5 2 0 0 2 2 2 2 Syntaxin-like protein DUF2203 PF09969.9 KUM65622.1 - 1.5 9.5 5.3 2.2 9.0 0.9 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Herpes_DNAp_acc PF04929.12 KUM65622.1 - 1.7 7.5 12.7 2.4 7.0 12.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Ndc1_Nup PF09531.10 KUM65622.1 - 2.4 6.7 8.0 3.5 6.2 8.0 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF572 PF04502.13 KUM65622.1 - 3 7.4 14.9 4.1 6.9 14.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Uso1_p115_C PF04871.13 KUM65622.1 - 3.3 8.1 17.6 5.3 7.4 3.1 2.4 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region PSK_trans_fac PF07704.11 KUM65622.1 - 3.3 8.5 9.5 1.3 9.9 4.7 2.5 2 1 0 2 2 2 0 Rv0623-like transcription factor IGPS PF00218.21 KUM65623.1 - 1.2e-97 326.0 0.0 2.6e-97 325.0 0.0 1.6 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 KUM65623.1 - 2.9e-57 193.6 0.0 1.8e-55 187.7 0.0 2.5 1 1 1 2 2 2 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 KUM65623.1 - 1.8e-47 161.6 0.0 3.2e-47 160.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I QRPTase_C PF01729.19 KUM65623.1 - 2.4e-05 24.2 0.2 0.0018 18.1 0.0 3.0 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain Peptidase_C26 PF07722.13 KUM65623.1 - 2.9e-05 23.9 0.2 8.3e-05 22.4 0.2 1.7 1 1 0 1 1 1 1 Peptidase C26 IMPDH PF00478.25 KUM65623.1 - 0.023 13.7 0.0 1.6 7.7 0.0 3.0 3 1 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain NanE PF04131.14 KUM65623.1 - 0.025 13.7 0.7 0.22 10.7 0.0 2.8 4 0 0 4 4 4 0 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 KUM65623.1 - 0.041 13.3 0.1 0.28 10.6 0.0 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein Peripla_BP_2 PF01497.18 KUM65623.1 - 0.054 13.1 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Nup188_C PF18378.1 KUM65624.1 - 4.4e-142 473.3 3.3 6.8e-142 472.7 3.3 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KUM65624.1 - 3.6e-82 276.7 0.0 1.4e-81 274.8 0.0 1.9 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Brix PF04427.18 KUM65625.1 - 3.3e-31 108.9 0.0 4.2e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Brix domain PTCB-BRCT PF12738.7 KUM65626.1 - 3.1e-05 23.8 0.0 6.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KUM65626.1 - 4.4e-05 23.8 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KUM65626.1 - 0.001 19.4 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain WGR PF05406.15 KUM65626.1 - 0.0012 18.8 1.8 0.0022 18.0 0.2 2.1 2 0 0 2 2 2 1 WGR domain DUF4396 PF14342.6 KUM65627.1 - 8.7e-25 87.7 7.1 1.2e-24 87.3 7.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) UPF1_Zn_bind PF09416.10 KUM65628.1 - 7.2e-72 240.3 1.8 1.2e-71 239.6 0.7 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KUM65628.1 - 5.7e-60 202.3 0.0 1.1e-59 201.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KUM65628.1 - 7.7e-54 183.2 2.5 1.8e-30 106.6 0.2 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KUM65628.1 - 1.4e-32 111.8 0.0 2.6e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KUM65628.1 - 1.7e-13 50.7 0.2 1.6e-12 47.5 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KUM65628.1 - 6e-11 42.9 0.1 2.1e-10 41.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KUM65628.1 - 5e-06 26.6 0.0 9.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KUM65628.1 - 2.6e-05 24.1 0.1 0.39 10.4 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KUM65628.1 - 0.00051 19.4 0.1 0.011 14.9 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KUM65628.1 - 0.0006 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 KUM65628.1 - 0.0029 16.8 0.1 0.56 9.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase UvrD-helicase PF00580.21 KUM65628.1 - 0.0038 16.8 0.0 0.041 13.4 0.1 2.4 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 KUM65628.1 - 0.012 15.4 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase ATPase PF06745.13 KUM65628.1 - 0.055 12.8 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_10 PF12846.7 KUM65628.1 - 0.069 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 KUM65628.1 - 0.14 12.5 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KUM65628.1 - 0.27 11.7 0.5 0.73 10.3 0.5 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HECT_2 PF09814.9 KUM65629.1 - 6.2e-111 370.9 0.0 7e-111 370.7 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 KUM65629.1 - 0.053 13.7 2.1 0.35 11.1 2.1 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly XPA_N PF01286.18 KUM65629.1 - 0.14 12.2 0.4 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 XPA protein N-terminal TauD PF02668.16 KUM65630.1 - 3.5e-59 200.8 1.0 4.3e-59 200.5 1.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_2 PF00890.24 KUM65631.1 - 1.3e-125 419.8 3.4 1.5e-125 419.5 3.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KUM65631.1 - 1.7e-44 150.9 1.5 2.6e-44 150.3 1.5 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KUM65631.1 - 3.1e-07 29.9 1.4 0.00077 18.8 0.6 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KUM65631.1 - 1.3e-05 24.5 0.9 0.018 14.1 1.2 2.4 3 0 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.17 KUM65631.1 - 4.2e-05 22.9 0.2 0.036 13.3 0.0 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KUM65631.1 - 0.0011 18.3 0.1 0.0024 17.2 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KUM65631.1 - 0.022 14.4 1.5 0.091 12.3 1.5 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase PAPS_reduct PF01507.19 KUM65631.1 - 0.066 13.2 0.2 0.11 12.5 0.2 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family HI0933_like PF03486.14 KUM65631.1 - 0.27 9.9 1.5 1.1 7.9 0.5 2.3 3 0 0 3 3 3 0 HI0933-like protein LcrG PF07216.12 KUM65633.1 - 0.033 14.1 0.0 0.075 13.0 0.0 1.6 1 0 0 1 1 1 0 LcrG protein Lyase_1 PF00206.20 KUM65634.1 - 1.5e-87 293.9 0.0 2.4e-87 293.2 0.0 1.4 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KUM65634.1 - 1.9e-23 82.9 0.1 6.4e-23 81.3 0.1 1.9 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DPPIV_N PF00930.21 KUM65635.1 - 1.1e-112 376.3 0.0 1.6e-112 375.8 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KUM65635.1 - 4.5e-53 179.9 1.1 7.9e-53 179.1 1.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KUM65635.1 - 0.00043 20.0 3.1 0.001 18.7 2.3 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 KUM65635.1 - 0.026 13.2 0.0 0.096 11.3 0.0 1.8 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) PAF-AH_p_II PF03403.13 KUM65635.1 - 0.041 12.4 0.0 2.5 6.5 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.20 KUM65635.1 - 0.082 12.5 0.2 0.32 10.6 0.2 1.8 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KUM65635.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cpn60_TCP1 PF00118.24 KUM65636.1 - 8.9e-130 433.6 9.8 9.9e-130 433.4 9.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 KUM65637.1 - 1.6e-06 27.1 0.1 1.9e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA PF00004.29 KUM65638.1 - 1.5e-40 138.7 0.0 2.6e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KUM65638.1 - 8.6e-06 25.5 0.1 2e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KUM65638.1 - 9.1e-05 22.8 0.0 0.0059 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KUM65638.1 - 0.00013 22.0 0.1 0.00062 19.8 0.0 2.1 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KUM65638.1 - 0.00041 20.5 0.0 0.0013 18.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KUM65638.1 - 0.00055 20.4 0.1 0.011 16.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KUM65638.1 - 0.0015 17.8 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KUM65638.1 - 0.0094 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KUM65638.1 - 0.029 13.9 0.0 0.095 12.2 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KUM65638.1 - 0.03 14.6 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KUM65638.1 - 0.052 13.7 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KUM65638.1 - 0.06 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KUM65638.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KUM65638.1 - 0.095 12.4 0.1 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KUM65638.1 - 0.1 12.3 0.1 0.27 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KUM65638.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain FR47 PF08445.10 KUM65639.1 - 1.8e-06 27.8 0.0 0.0019 18.1 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein GlyL_C PF12524.8 KUM65639.1 - 0.034 14.3 0.3 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 dsDNA virus glycoprotein L C terminal Acetyltransf_1 PF00583.25 KUM65639.1 - 0.2 11.9 0.0 0.53 10.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Met_10 PF02475.16 KUM65641.1 - 1.5e-65 220.7 0.0 2.2e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 KUM65641.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase RNA_pol_Rpb4 PF03874.16 KUM65642.1 - 5.9e-26 91.2 2.1 7.9e-26 90.8 2.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Cut8 PF08559.10 KUM65642.1 - 0.0025 17.5 0.6 0.003 17.2 0.6 1.2 1 1 0 1 1 1 1 Cut8, nuclear proteasome tether protein AA_permease_2 PF13520.6 KUM65644.1 - 1e-56 192.6 51.7 1.3e-56 192.3 51.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM65644.1 - 7.9e-18 64.3 42.8 1.2e-17 63.7 42.8 1.2 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 KUM65644.1 - 0.64 10.0 0.0 0.64 10.0 0.0 2.8 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Questin_oxidase PF14027.6 KUM65645.1 - 2.2e-74 251.0 0.0 2.6e-74 250.8 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like DUF3818 PF12825.7 KUM65647.1 - 1.4e-130 435.3 2.9 2.2e-130 434.6 2.9 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KUM65647.1 - 4.1e-37 127.1 0.2 7.5e-37 126.2 0.2 1.4 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KUM65647.1 - 5.1e-15 55.4 0.6 2.3e-14 53.3 0.1 2.4 2 1 0 2 2 2 1 PX domain Vps5 PF09325.10 KUM65647.1 - 0.0018 17.9 0.7 0.0045 16.6 0.7 1.6 1 0 0 1 1 1 1 Vps5 C terminal like zf-C2H2 PF00096.26 KUM65648.1 - 0.00014 22.1 2.5 0.00014 22.1 2.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KUM65648.1 - 0.68 10.5 19.5 6 7.5 3.1 3.7 3 0 0 3 3 3 0 Zinc-finger double domain DUF3432 PF11914.8 KUM65648.1 - 1.3 9.3 12.0 3.3 8.0 10.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) zf-GRF PF06839.12 KUM65649.1 - 3.8e-08 33.3 5.5 6.6e-08 32.5 5.5 1.4 1 0 0 1 1 1 1 GRF zinc finger Ank_2 PF12796.7 KUM65650.1 - 6.9e-72 238.1 0.0 2.7e-12 47.1 0.0 6.1 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 KUM65650.1 - 5.4e-37 124.6 0.4 0.00014 22.2 0.2 10.8 9 1 1 10 10 10 8 Ankyrin repeat Ank_3 PF13606.6 KUM65650.1 - 3.9e-35 115.9 0.1 0.00033 20.8 0.0 10.2 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.6 KUM65650.1 - 2.1e-34 117.4 0.0 3.8e-07 30.5 0.0 7.2 3 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM65650.1 - 3e-32 110.3 2.9 5.2e-09 36.2 0.0 8.4 2 2 7 9 9 9 9 Ankyrin repeats (many copies) AAA PF00004.29 KUM65651.1 - 1.1e-47 161.8 0.0 5.4e-43 146.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KUM65651.1 - 5.1e-05 23.0 10.3 8.5e-05 22.3 0.1 3.5 3 1 0 3 3 2 1 AAA+ lid domain AAA_16 PF13191.6 KUM65651.1 - 7.3e-05 23.2 0.0 0.022 15.2 0.0 3.4 3 0 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 KUM65651.1 - 0.00016 21.4 0.0 0.00043 20.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 KUM65651.1 - 0.00058 19.0 0.0 0.00097 18.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.6 KUM65651.1 - 0.0034 17.7 0.0 0.046 14.0 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 KUM65651.1 - 0.0035 17.5 0.0 0.0098 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KUM65651.1 - 0.0044 17.4 0.0 0.015 15.7 0.0 2.0 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 KUM65651.1 - 0.007 15.6 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 KUM65651.1 - 0.0073 15.9 0.2 0.041 13.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KUM65651.1 - 0.0095 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KUM65651.1 - 0.016 14.7 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KUM65651.1 - 0.029 13.8 0.1 0.055 12.8 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KUM65651.1 - 0.041 13.2 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 KUM65651.1 - 0.043 13.8 0.0 0.13 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KUM65651.1 - 0.051 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KUM65651.1 - 0.064 13.4 0.1 0.45 10.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 KUM65651.1 - 0.064 13.3 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KUM65651.1 - 0.099 12.9 0.0 0.32 11.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 KUM65651.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Vps4_C PF09336.10 KUM65651.1 - 0.18 11.9 0.1 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Fungal_trans PF04082.18 KUM65652.1 - 1.4e-10 40.7 1.6 2.3e-10 40.0 1.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_10 PF00331.20 KUM65656.1 - 3e-71 240.2 0.0 3.4e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 KUM65656.1 - 0.027 13.8 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase Fungal_trans PF04082.18 KUM65657.1 - 5.5e-19 68.2 0.2 1e-18 67.4 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM65657.1 - 0.0016 18.5 6.4 0.0036 17.4 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.21 KUM65657.1 - 0.19 11.2 0.1 0.79 9.1 0.0 1.9 2 0 0 2 2 2 0 Dioxygenase Ribosomal_L21p PF00829.21 KUM65658.1 - 2e-09 37.6 0.0 2.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Ribosomal_S8e PF01201.22 KUM65659.1 - 5.2e-45 153.0 3.7 7.7e-45 152.4 3.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e RIBIOP_C PF04950.12 KUM65659.1 - 1.1 8.7 8.5 2.7 7.4 8.5 1.6 1 1 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Glyco_transf_28 PF03033.20 KUM65660.1 - 8.2e-25 87.5 0.0 1.7e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KUM65660.1 - 0.015 14.1 0.1 0.023 13.5 0.1 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 KUM65660.1 - 0.022 14.5 0.5 0.05 13.4 0.2 1.7 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal DUF1338 PF07063.13 KUM65661.1 - 5.6e-109 364.3 0.0 6.6e-109 364.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Glyco_trans_1_4 PF13692.6 KUM65662.1 - 4.3e-11 43.4 0.0 1e-10 42.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KUM65662.1 - 5.6e-11 42.3 0.0 1.3e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 KUM65662.1 - 0.03 14.1 0.0 0.073 12.8 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3492) Tissue_fac PF01108.17 KUM65663.1 - 0.024 14.5 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 Tissue factor GST_N_3 PF13417.6 KUM65664.1 - 3.3e-08 33.8 0.0 5.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KUM65664.1 - 3.1e-06 27.4 0.0 5.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KUM65664.1 - 0.00084 19.3 0.1 0.0014 18.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KUM65664.1 - 0.0056 16.9 0.0 0.0088 16.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KUM65664.1 - 0.046 13.9 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PI-PLC-X PF00388.19 KUM65665.1 - 4.2e-59 198.3 0.0 8.6e-59 197.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KUM65665.1 - 2.3e-38 131.1 0.1 4e-38 130.3 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain AF-4 PF05110.13 KUM65665.1 - 0.027 12.6 8.3 0.041 12.0 8.3 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MFS_1 PF07690.16 KUM65667.1 - 5.4e-24 84.8 21.0 5.4e-24 84.8 21.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3446 PF11928.8 KUM65667.1 - 0.0052 17.1 0.2 0.069 13.5 0.2 2.4 2 0 0 2 2 2 1 Early growth response N-terminal domain DUF4500 PF14937.6 KUM65667.1 - 0.013 15.5 0.1 0.033 14.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) Glyco_hydro_114 PF03537.13 KUM65668.1 - 4.8e-85 284.6 1.7 6e-85 284.3 1.7 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Spherulin4 PF12138.8 KUM65669.1 - 3e-74 249.7 0.6 3.5e-74 249.5 0.6 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Pilin_N PF07790.11 KUM65669.1 - 0.081 13.8 0.8 0.2 12.6 0.8 1.7 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Epimerase PF01370.21 KUM65670.1 - 6.5e-37 127.3 0.0 4e-36 124.7 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM65670.1 - 2.6e-35 122.4 0.0 9.6e-35 120.5 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KUM65670.1 - 8.6e-09 34.9 0.0 6.4e-07 28.8 0.0 2.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KUM65670.1 - 2.5e-07 30.1 0.1 0.0001 21.6 0.0 2.4 2 1 1 3 3 3 2 Male sterility protein 3Beta_HSD PF01073.19 KUM65670.1 - 7.2e-07 28.5 0.0 6.3e-06 25.4 0.0 2.4 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox_2 PF07992.14 KUM65670.1 - 0.00063 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 KUM65670.1 - 0.0016 18.0 0.0 0.0096 15.4 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KUM65670.1 - 0.0028 17.6 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KUM65670.1 - 0.0062 15.7 0.0 0.041 13.0 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 KUM65670.1 - 0.061 13.6 0.0 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KUM65670.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ribosomal_L37 PF08561.10 KUM65671.1 - 4.7e-41 140.1 0.6 6.1e-41 139.7 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 KR PF08659.10 KUM65672.1 - 2.4e-34 118.8 0.0 3.6e-19 69.4 0.0 2.5 1 1 1 2 2 2 2 KR domain Methyltransf_12 PF08242.12 KUM65672.1 - 2.3e-13 50.7 0.1 1.6e-12 48.0 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM65672.1 - 2.1e-10 40.7 0.0 4.5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM65672.1 - 4e-09 37.0 0.0 1.8e-08 34.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM65672.1 - 9.2e-08 32.7 0.1 1.1e-06 29.2 0.1 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM65672.1 - 7.1e-07 29.1 0.0 1.6e-05 24.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KUM65672.1 - 9.1e-07 28.5 0.0 0.0029 17.1 0.0 2.8 1 1 1 2 2 2 2 short chain dehydrogenase Ubie_methyltran PF01209.18 KUM65672.1 - 0.0051 16.2 0.0 0.0092 15.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KUM65672.1 - 0.025 14.4 0.1 0.15 11.9 0.0 2.0 1 1 1 2 2 2 0 Hypothetical methyltransferase RrnaAD PF00398.20 KUM65672.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.12 KUM65672.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DREV PF05219.12 KUM65672.1 - 0.18 10.9 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase FAD_binding_3 PF01494.19 KUM65673.1 - 7.5e-07 28.7 0.0 1.1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Vma12 PF11712.8 KUM65673.1 - 0.15 12.1 0.2 0.41 10.7 0.2 1.7 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pkinase PF00069.25 KUM65674.1 - 3.7e-46 157.6 0.0 5.6e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM65674.1 - 3.4e-16 59.3 0.0 5.3e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KUM65674.1 - 0.0058 16.2 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KUM65674.1 - 0.0093 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KUM65674.1 - 0.019 14.9 0.0 0.29 11.0 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KUM65674.1 - 0.047 13.1 0.1 0.077 12.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KUM65674.1 - 0.071 11.9 0.0 0.071 11.9 0.0 2.1 3 0 0 3 3 3 0 Fungal protein kinase PWI PF01480.17 KUM65675.1 - 1.3e-29 102.3 0.1 2e-29 101.7 0.1 1.3 1 0 0 1 1 1 1 PWI domain DUF2951 PF11166.8 KUM65675.1 - 0.26 11.5 5.2 3.7 7.8 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) NGP1NT PF08153.12 KUM65677.1 - 6.6e-49 165.4 0.2 1e-48 164.8 0.2 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KUM65677.1 - 3.6e-17 62.5 0.0 1.5e-13 50.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KUM65677.1 - 1e-05 25.1 0.0 7.2e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 KUM65677.1 - 0.00032 20.2 0.0 0.097 12.1 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 KUM65677.1 - 0.00034 20.7 0.1 0.37 10.8 0.0 3.5 2 1 1 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 KUM65677.1 - 0.0023 17.9 0.0 0.0063 16.4 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase Roc PF08477.13 KUM65677.1 - 0.042 14.1 0.0 17 5.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KUM65677.1 - 0.1 13.1 0.0 3.6 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KUM65678.1 - 7.3e-08 32.5 0.1 3.5e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Ank_4 PF13637.6 KUM65678.1 - 5.7e-05 23.6 0.0 0.0062 17.1 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 KUM65678.1 - 9.2e-05 22.9 1.0 0.00027 21.4 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain Ank_2 PF12796.7 KUM65678.1 - 0.00014 22.3 0.0 0.00044 20.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) NB-ARC PF00931.22 KUM65678.1 - 0.00027 20.2 0.1 0.001 18.3 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain Helo_like_N PF17111.5 KUM65678.1 - 0.00062 19.2 1.8 0.0024 17.3 1.7 2.1 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 KUM65678.1 - 0.0012 19.1 0.1 0.0057 16.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain ATPase_2 PF01637.18 KUM65678.1 - 0.0018 18.2 0.0 0.0051 16.7 0.0 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 KUM65678.1 - 0.0021 18.5 0.3 0.011 16.1 0.3 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KUM65678.1 - 0.0061 16.6 0.1 0.15 12.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain Ank_5 PF13857.6 KUM65678.1 - 0.014 15.7 0.0 1.9 8.9 0.0 2.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM65678.1 - 0.021 15.3 0.0 11 7.0 0.0 3.3 2 0 0 2 2 2 0 Ankyrin repeat AAA_33 PF13671.6 KUM65678.1 - 0.041 14.1 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 KUM65678.1 - 0.064 11.9 0.2 0.097 11.3 0.2 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase PIF1 PF05970.14 KUM65678.1 - 0.077 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase RsgA_GTPase PF03193.16 KUM65678.1 - 0.094 12.6 0.4 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 KUM65678.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.6 KUM65678.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KUM65678.1 - 0.15 11.8 0.3 0.7 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KUM65678.1 - 0.15 12.4 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KUM65678.1 - 0.15 12.5 0.1 0.6 10.6 0.0 2.0 2 0 0 2 2 1 0 ABC transporter MAT1 PF06391.13 KUM65679.1 - 6.7e-43 146.9 13.4 9.7e-43 146.4 13.4 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KUM65679.1 - 2.3e-32 110.6 8.6 3.6e-32 110.0 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KUM65679.1 - 5.7e-05 22.9 5.5 0.00011 22.0 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KUM65679.1 - 0.0003 20.6 3.6 0.00063 19.5 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM65679.1 - 0.00036 20.3 4.9 0.0013 18.6 5.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KUM65679.1 - 0.0015 18.9 6.1 0.0026 18.1 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KUM65679.1 - 0.0038 17.0 6.2 0.036 13.9 1.9 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KUM65679.1 - 0.0053 16.4 1.4 0.011 15.3 1.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KUM65679.1 - 0.011 15.7 7.7 0.11 12.4 8.2 2.1 1 1 1 2 2 2 0 zinc-RING finger domain Cas_GSU0054 PF09609.10 KUM65679.1 - 0.048 12.4 0.0 0.065 11.9 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) DUF3797 PF12677.7 KUM65679.1 - 0.056 13.3 2.4 0.15 12.0 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-RING_UBOX PF13445.6 KUM65679.1 - 0.21 11.6 6.0 0.43 10.6 6.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Nup88 PF10168.9 KUM65679.1 - 0.6 7.8 6.6 0.83 7.4 6.6 1.1 1 0 0 1 1 1 0 Nuclear pore component Prok-RING_4 PF14447.6 KUM65679.1 - 0.67 9.9 7.9 16 5.4 8.7 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Cep57_MT_bd PF06657.13 KUM65680.1 - 1.7e-29 102.1 0.1 1.7e-29 102.1 0.1 5.1 6 1 0 6 6 6 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 KUM65680.1 - 2.1e-20 72.5 11.8 2.1e-20 72.5 11.8 4.2 4 1 0 4 4 4 2 Centrosome localisation domain of PPC89 ZapB PF06005.12 KUM65680.1 - 0.055 13.9 0.6 0.055 13.9 0.6 5.7 5 2 1 6 6 6 0 Cell division protein ZapB Spore_III_AB PF09548.10 KUM65680.1 - 0.55 10.3 6.5 0.88 9.7 0.2 3.4 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Shugoshin_N PF07558.11 KUM65680.1 - 2.2 8.2 8.8 0.64 9.9 3.2 3.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Peptidase_M6 PF05547.11 KUM65681.1 - 0.0048 15.3 0.7 0.0075 14.7 0.7 1.3 1 0 0 1 1 1 1 Immune inhibitor A peptidase M6 Peptidase_M7 PF02031.16 KUM65681.1 - 0.037 14.1 0.3 0.19 11.8 0.2 2.1 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family DUF4124 PF13511.6 KUM65681.1 - 0.14 12.5 0.1 0.37 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) Pkinase PF00069.25 KUM65683.1 - 4.9e-42 144.1 0.0 1.8e-41 142.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM65683.1 - 5.6e-28 97.9 0.0 7.9e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM65683.1 - 4.9e-05 22.8 0.0 0.00013 21.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KUM65683.1 - 0.00041 19.3 0.0 0.00063 18.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KUM65683.1 - 0.00049 19.5 0.1 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KUM65683.1 - 0.0012 18.8 0.3 0.03 14.2 0.3 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fungal_trans PF04082.18 KUM65684.1 - 4.4e-17 62.0 0.1 8e-17 61.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM65684.1 - 1.2e-07 31.8 8.9 2.1e-07 30.9 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KUM65685.1 - 7.6e-18 64.7 0.0 4.1e-15 55.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KUM65685.1 - 1.5e-06 28.3 0.1 3.2e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KUM65685.1 - 2.6e-05 23.9 0.0 0.00011 21.8 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Prefoldin_3 PF13758.6 KUM65686.1 - 4.7e-36 122.8 0.2 1.3e-35 121.4 0.2 1.8 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 KUM65686.1 - 8.5e-14 52.2 2.4 8.5e-14 52.2 2.4 5.2 4 2 1 5 5 5 2 Domain of unknown function (DUF3835) CCDC-167 PF15188.6 KUM65686.1 - 5.1 7.5 5.3 26 5.2 0.2 3.4 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 167 zf-C2H2_4 PF13894.6 KUM65687.1 - 3.3e-06 27.5 1.9 0.055 14.3 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KUM65687.1 - 0.001 19.4 3.0 0.055 14.0 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type HDV_ag PF01517.18 KUM65687.1 - 0.046 13.5 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen zf-C2H2_6 PF13912.6 KUM65687.1 - 0.2 11.7 1.1 0.58 10.2 0.4 2.1 1 1 1 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 KUM65687.1 - 0.29 11.5 1.6 6.9 7.1 0.5 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Tmemb_14 PF03647.13 KUM65688.1 - 5.8e-19 68.6 9.7 7.2e-19 68.3 9.7 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C ATP19 PF11022.8 KUM65688.1 - 0.53 10.7 3.8 15 6.1 0.1 2.7 2 1 1 3 3 3 0 ATP synthase subunit K Zn_clus PF00172.18 KUM65689.1 - 0.0039 17.3 9.9 0.0084 16.2 9.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_helicase PF00910.22 KUM65689.1 - 0.16 12.3 0.1 1.8 9.0 0.0 2.6 3 0 0 3 3 3 0 RNA helicase BAALC_N PF06989.12 KUM65689.1 - 6.3 7.2 6.5 6.6 7.1 0.1 3.5 3 0 0 3 3 3 0 BAALC N-terminus SurE PF01975.17 KUM65690.1 - 1.8e-52 177.9 0.0 2.5e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE DUF2462 PF09495.10 KUM65692.1 - 3e-20 72.7 3.7 3e-20 72.7 3.7 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) tRNA-synt_1c PF00749.21 KUM65693.1 - 6e-99 330.9 0.0 8e-99 330.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KUM65693.1 - 4.2e-36 124.4 0.1 8.8e-36 123.4 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 KUM65693.1 - 0.0039 17.2 0.1 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GluRS_N PF18466.1 KUM65693.1 - 0.012 16.0 0.0 0.32 11.4 0.0 2.9 2 0 0 2 2 2 0 Glutamate--tRNA ligase N-terminal domain GST_C PF00043.25 KUM65693.1 - 0.033 14.4 0.0 0.086 13.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KUM65693.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 KUM65693.1 - 0.17 11.2 0.2 0.52 9.6 0.1 1.7 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-C2H2_12 PF18658.1 KUM65694.1 - 0.059 13.0 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Zinc-finger C2H2-type Forkhead_N PF08430.12 KUM65694.1 - 0.17 12.5 6.6 2.6 8.7 3.0 2.4 2 0 0 2 2 2 0 Forkhead N-terminal region DBINO PF13892.6 KUM65694.1 - 0.32 11.4 4.6 0.59 10.5 1.7 2.3 2 0 0 2 2 2 0 DNA-binding domain API5 PF05918.11 KUM65694.1 - 1.3 7.7 4.9 2.6 6.8 4.9 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF5427 PF10310.9 KUM65695.1 - 3e-165 550.7 0.4 3.5e-165 550.5 0.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 KUM65695.1 - 0.12 12.6 0.3 0.12 12.6 0.3 2.2 2 1 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain SARAF PF06682.12 KUM65695.1 - 0.19 11.3 6.1 0.32 10.6 6.1 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CMD PF02627.20 KUM65696.1 - 4.4e-07 29.9 0.0 9e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family CARD_2 PF16739.5 KUM65696.1 - 0.096 12.7 0.0 1 9.4 0.0 2.1 1 1 1 2 2 2 0 Caspase recruitment domain IMS PF00817.20 KUM65698.1 - 1.3e-35 122.6 0.0 5.7e-34 117.3 0.0 2.3 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KUM65698.1 - 4.8e-15 56.3 0.0 1.3e-14 54.9 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KUM65698.1 - 2.6e-13 49.3 1.3 6.2e-13 48.1 1.3 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger AAA_12 PF13087.6 KUM65699.1 - 5.2e-42 143.7 0.0 8.6e-42 143.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KUM65699.1 - 9.5e-24 84.6 0.0 1.7e-13 51.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KUM65699.1 - 5.2e-09 36.1 0.0 4e-07 30.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KUM65699.1 - 1.4e-08 35.2 0.0 3.7e-07 30.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KUM65699.1 - 7.7e-05 22.8 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KUM65699.1 - 0.00044 20.1 0.1 0.027 14.2 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KUM65699.1 - 0.0056 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DEAD PF00270.29 KUM65699.1 - 0.0091 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase CDT1_C PF16679.5 KUM65699.1 - 0.037 14.4 0.1 0.22 12.0 0.0 2.3 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain DUF2075 PF09848.9 KUM65699.1 - 0.052 12.8 0.0 0.62 9.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Fungal_trans PF04082.18 KUM65700.1 - 1.7e-14 53.5 0.4 3.5e-14 52.5 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KUM65701.1 - 4.9e-59 199.7 0.6 8.5e-59 198.9 0.6 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM65701.1 - 2.6e-44 151.0 0.1 4e-44 150.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM65701.1 - 3.3e-08 33.6 0.2 2.1e-07 31.0 0.2 2.0 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KUM65701.1 - 0.0036 16.5 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 KUM65701.1 - 0.0058 17.3 0.1 0.013 16.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF5448 PF17526.2 KUM65701.1 - 0.024 14.8 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5448) Epimerase PF01370.21 KUM65701.1 - 0.029 13.8 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KUM65701.1 - 0.097 12.7 0.8 0.38 10.7 0.8 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Ferredoxin_N PF16947.5 KUM65701.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 N-terminal region of 4Fe-4S ferredoxin iron-sulfur binding Amidase PF01425.21 KUM65702.1 - 3.6e-90 303.1 0.1 4.7e-90 302.7 0.1 1.1 1 0 0 1 1 1 1 Amidase DUF3445 PF11927.8 KUM65703.1 - 1.1e-76 257.4 0.0 1.4e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) PRP38 PF03371.15 KUM65704.1 - 1.7e-63 213.6 0.0 2.1e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 PRP38 family CBM_20 PF00686.19 KUM65705.1 - 0.062 13.2 0.1 0.98 9.4 0.0 2.4 2 0 0 2 2 2 0 Starch binding domain WD40 PF00400.32 KUM65706.1 - 4.1e-16 59.1 1.1 0.97 10.4 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM65706.1 - 0.0017 18.6 0.0 12 6.3 0.0 3.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Polysacc_deac_1 PF01522.21 KUM65707.1 - 1.5e-18 66.9 0.0 2.9e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KUM65707.1 - 4.1e-06 26.6 0.2 1.1e-05 25.2 0.2 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KUM65707.1 - 0.13 10.6 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) APH PF01636.23 KUM65710.1 - 4.1e-06 26.9 0.8 0.012 15.5 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KUM65710.1 - 5.2e-06 26.0 0.3 1.2e-05 24.8 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KUM65710.1 - 1.5e-05 24.7 0.4 2.6e-05 23.9 0.3 1.5 1 1 0 1 1 1 1 RIO1 family WaaY PF06176.11 KUM65710.1 - 0.00021 21.0 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_fungal PF17667.1 KUM65710.1 - 0.00072 18.4 0.0 0.00076 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KUM65710.1 - 0.00079 19.1 0.6 0.15 11.6 0.3 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase Pkinase PF00069.25 KUM65710.1 - 0.00098 18.6 0.1 0.0013 18.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain FTA2 PF13095.6 KUM65710.1 - 0.08 12.5 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RTA1 PF04479.13 KUM65711.1 - 4.2e-23 82.0 1.5 4.2e-23 82.0 1.5 1.6 2 0 0 2 2 2 1 RTA1 like protein CPBP PF02517.16 KUM65711.1 - 1.7 9.1 5.1 3.9 7.9 5.1 2.0 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease Oxidored_molyb PF00174.19 KUM65712.1 - 3.9e-57 192.6 0.0 6.8e-57 191.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KUM65712.1 - 4e-35 120.8 0.2 9.9e-35 119.5 0.2 1.7 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 KUM65712.1 - 1e-24 87.2 0.0 1e-24 87.2 0.0 3.9 5 0 0 5 5 5 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KUM65712.1 - 4e-21 75.2 0.0 8.4e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KUM65712.1 - 1.8e-17 63.3 0.1 4.2e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KUM65712.1 - 0.00047 20.3 0.0 0.029 14.5 0.0 2.8 1 1 1 2 2 2 1 Ferric reductase NAD binding domain WSC PF01822.19 KUM65713.1 - 1.1e-07 32.0 11.6 1.1e-07 32.0 11.6 2.5 2 1 0 2 2 2 1 WSC domain Amnionless PF14828.6 KUM65713.1 - 0.0014 17.5 0.1 0.002 17.1 0.1 1.2 1 0 0 1 1 1 1 Amnionless RIFIN PF02009.16 KUM65713.1 - 0.049 13.5 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Rifin DUF2207 PF09972.9 KUM65713.1 - 0.07 11.9 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SKG6 PF08693.10 KUM65713.1 - 0.11 11.9 0.2 0.55 9.7 0.2 2.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KUM65713.1 - 0.14 12.0 0.8 0.3 10.9 0.8 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 BatA PF07584.11 KUM65713.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Apt1 PF10351.9 KUM65713.1 - 0.27 10.0 4.6 0.31 9.9 4.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Podoplanin PF05808.11 KUM65713.1 - 0.45 10.6 23.4 1.2 9.2 23.4 1.7 1 1 0 1 1 1 0 Podoplanin DUF3664 PF12406.8 KUM65713.1 - 0.95 10.1 2.9 1.7 9.3 2.9 1.4 1 0 0 1 1 1 0 Surface protein Sugar_tr PF00083.24 KUM65714.1 - 2.1e-117 392.8 18.7 3.3e-117 392.1 18.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM65714.1 - 1.6e-25 89.8 39.1 2.8e-25 89.0 34.5 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily RTC4 PF14474.6 KUM65716.1 - 6e-32 110.4 0.0 1.2e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain TFR_dimer PF04253.15 KUM65717.1 - 2.2e-30 105.2 0.0 3.5e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KUM65717.1 - 2.7e-20 72.9 0.0 4.1e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KUM65717.1 - 6.6e-09 35.7 0.3 1.6e-08 34.4 0.1 1.8 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.15 KUM65717.1 - 0.0042 16.6 0.0 0.0081 15.7 0.0 1.4 1 0 0 1 1 1 1 Nicastrin Homeobox_KN PF05920.11 KUM65718.1 - 1.8e-20 72.6 0.2 5.7e-20 70.9 0.2 2.0 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KUM65718.1 - 1.3e-05 25.0 0.2 4.3e-05 23.3 0.2 2.0 1 0 0 1 1 1 1 Homeodomain DUF5333 PF17267.2 KUM65718.1 - 0.00014 22.0 5.1 0.043 14.0 0.8 2.9 1 1 1 2 2 2 2 Family of unknown function (DUF5333) SAM_KSR1 PF13543.6 KUM65718.1 - 0.025 14.7 3.3 0.075 13.2 3.3 1.8 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 Mog1 PF04603.12 KUM65718.1 - 1.4 9.3 6.3 0.82 10.0 0.5 2.6 2 0 0 2 2 2 0 Ran-interacting Mog1 protein zf-Di19 PF05605.12 KUM65718.1 - 3.7 7.9 4.9 38 4.7 0.6 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF726 PF05277.12 KUM65721.1 - 4.2e-128 427.1 3.4 6e-128 426.6 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Fungal_trans PF04082.18 KUM65722.1 - 3.7e-06 26.2 0.2 6.7e-06 25.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM65722.1 - 0.0022 18.1 11.3 0.0034 17.5 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2418 PF10332.9 KUM65723.1 - 0.24 11.9 3.0 0.27 11.8 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) Zn_clus PF00172.18 KUM65724.1 - 3.2e-05 24.0 2.2 6e-05 23.1 2.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM65724.1 - 0.048 12.5 0.6 0.13 11.1 0.6 1.6 1 1 0 1 1 1 0 Fungal specific transcription factor domain ATP-grasp_3 PF02655.14 KUM65724.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain RTA1 PF04479.13 KUM65725.1 - 1.6e-27 96.5 1.1 1.6e-27 96.5 1.1 1.5 2 0 0 2 2 2 1 RTA1 like protein HNH_2 PF13391.6 KUM65726.1 - 2.2e-07 30.9 0.0 6.6e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 HNH endonuclease ELP6 PF09807.9 KUM65727.1 - 4.6e-15 55.7 0.0 1.6e-06 27.8 0.0 2.1 2 0 0 2 2 2 2 Elongation complex protein 6 ATPase PF06745.13 KUM65727.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 KaiC Fungal_trans PF04082.18 KUM65728.1 - 9e-28 97.0 0.1 1.3e-27 96.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM65728.1 - 3.7e-10 39.8 10.8 6.1e-10 39.1 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KUM65728.1 - 2.4e-05 24.4 0.1 4.6e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Gal4-like dimerisation domain Slu7 PF11708.8 KUM65729.1 - 6.9e-81 271.9 13.9 6.9e-81 271.9 13.9 2.3 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KUM65729.1 - 0.03 14.1 0.6 0.073 12.8 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle HpaB_N PF11794.8 KUM65729.1 - 0.045 13.4 1.5 1.1 8.9 0.0 2.5 2 1 0 3 3 3 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Ribosomal_L37e PF01907.19 KUM65730.1 - 1.9e-28 98.3 12.3 2.8e-28 97.8 12.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e CytoC_RC PF02276.18 KUM65730.1 - 0.00097 18.6 0.1 0.001 18.5 0.1 1.1 1 0 0 1 1 1 1 Photosynthetic reaction centre cytochrome C subunit DZR PF12773.7 KUM65730.1 - 0.0045 17.0 2.4 0.0072 16.3 2.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF35_N PF12172.8 KUM65730.1 - 0.071 13.0 2.4 0.13 12.2 2.4 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) HypA PF01155.19 KUM65730.1 - 0.081 12.9 0.6 0.11 12.6 0.6 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KUM65730.1 - 0.091 12.5 3.2 4 7.3 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KUM65730.1 - 0.19 11.2 3.8 0.68 9.4 3.8 1.8 1 1 0 1 1 1 0 zinc-ribbon domain DUF2688 PF10892.8 KUM65730.1 - 0.2 11.1 4.8 2.3 7.7 2.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) RdRP PF05183.12 KUM65731.1 - 4.2e-185 616.8 0.0 8.2e-185 615.8 0.0 1.5 2 0 0 2 2 2 1 RNA dependent RNA polymerase RRM_1 PF00076.22 KUM65731.1 - 3.1e-05 23.7 0.0 0.0001 22.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_B PF00136.21 KUM65732.1 - 4.6e-106 355.3 0.0 6.2e-106 354.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KUM65732.1 - 8.6e-20 71.1 0.0 9.5e-12 44.7 0.0 2.5 2 1 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KUM65732.1 - 2.6e-17 63.1 3.1 2.6e-17 63.1 3.1 2.1 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Glyco_transf_4 PF13439.6 KUM65732.1 - 0.022 14.8 0.6 6.8 6.7 0.1 2.9 2 1 0 2 2 2 0 Glycosyltransferase Family 4 FAD-oxidase_C PF02913.19 KUM65733.1 - 1.1e-65 221.7 0.0 1.5e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KUM65733.1 - 8.4e-36 122.8 0.0 1.5e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Baculo_PEP_C PF04513.12 KUM65734.1 - 2 8.4 13.4 4.1 7.4 2.2 3.4 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NmrA PF05368.13 KUM65735.1 - 2.9e-20 72.8 0.5 3.6e-20 72.5 0.5 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM65735.1 - 2.1e-16 60.4 0.2 9.5e-16 58.2 0.0 2.0 1 1 1 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KUM65735.1 - 4.6e-08 33.4 0.1 1.1e-07 32.2 0.1 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KUM65735.1 - 1.4e-05 25.2 0.0 2.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KUM65735.1 - 1.7e-05 25.3 2.3 2.9e-05 24.6 0.6 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent PglD_N PF17836.1 KUM65735.1 - 0.0021 18.7 0.4 0.0051 17.4 0.4 1.7 1 0 0 1 1 1 1 PglD N-terminal domain NAD_binding_7 PF13241.6 KUM65735.1 - 0.0034 17.8 0.7 0.0071 16.8 0.1 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding Gp_dh_N PF00044.24 KUM65735.1 - 0.011 16.0 0.2 0.038 14.3 0.0 2.0 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TrkA_N PF02254.18 KUM65735.1 - 0.032 14.5 0.7 0.059 13.6 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 KUM65735.1 - 0.05 13.0 0.1 0.094 12.1 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_M23_N PF18421.1 KUM65735.1 - 0.097 12.6 0.1 0.34 10.9 0.0 1.9 2 1 1 3 3 3 0 Peptidase family M23 N-terminal domain ApbA PF02558.16 KUM65735.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.18 KUM65736.1 - 3.9e-14 52.3 0.0 7.5e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_M20 PF01546.28 KUM65737.1 - 1.1e-29 103.6 0.0 2.7e-29 102.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KUM65737.1 - 2.1e-11 43.7 0.1 3.9e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KUM65737.1 - 0.00055 19.7 0.0 0.00093 18.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 DUF5127 PF17168.4 KUM65738.1 - 1e-84 283.9 6.2 1.6e-84 283.2 6.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KUM65738.1 - 4.4e-78 260.9 0.6 4.4e-78 260.9 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KUM65738.1 - 6.1e-67 225.2 0.2 6.1e-67 225.2 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KUM65738.1 - 3.6e-06 26.4 1.3 1.3e-05 24.6 1.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4964) Annexin PF00191.20 KUM65739.1 - 2.5e-12 46.7 2.9 0.00015 21.8 0.0 4.4 4 0 0 4 4 4 4 Annexin Septin PF00735.18 KUM65740.1 - 4.2e-35 121.4 0.0 5e-22 78.5 0.0 3.1 2 1 0 2 2 2 2 Septin MMR_HSR1 PF01926.23 KUM65740.1 - 0.00049 20.1 0.0 0.0014 18.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KUM65740.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 KUM65740.1 - 0.043 13.0 0.0 0.31 10.1 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit ABC_tran PF00005.27 KUM65740.1 - 0.087 13.3 0.1 0.92 10.0 0.3 2.2 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 KUM65740.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain TEX19 PF15553.6 KUM65740.1 - 0.17 11.9 0.5 0.29 11.1 0.5 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 Dynamin_N PF00350.23 KUM65740.1 - 0.18 11.9 3.0 0.26 11.3 0.0 2.5 3 1 0 3 3 3 0 Dynamin family Spem1 PF15670.5 KUM65740.1 - 0.29 10.7 1.8 1.4 8.5 0.0 2.7 2 1 1 3 3 3 0 Spermatid maturation protein 1 Vps62 PF06101.11 KUM65741.1 - 1.4e-11 43.4 0.4 2e-11 42.9 0.4 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 DOPA_dioxygen PF08883.11 KUM65742.1 - 4e-06 26.9 0.1 5.1e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family OmpH PF03938.14 KUM65744.1 - 0.22 11.8 10.9 1.5 9.2 2.1 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 KUM65744.1 - 0.26 11.3 4.2 0.87 9.6 1.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 KUM65744.1 - 0.32 11.3 2.4 0.44 10.8 0.7 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.9 KUM65744.1 - 0.66 10.0 14.2 0.33 11.0 4.5 2.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran_CTD PF16326.5 KUM65744.1 - 0.75 10.1 19.2 0.055 13.7 3.2 4.4 1 1 3 4 4 4 0 ABC transporter C-terminal domain BLOC1_2 PF10046.9 KUM65744.1 - 1.3 9.4 6.6 0.63 10.4 2.3 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 KUM65744.1 - 1.7 9.0 15.5 27 5.1 15.4 2.1 1 1 0 1 1 1 0 Fez1 Prefoldin PF02996.17 KUM65744.1 - 1.8 8.5 8.3 1.1 9.1 1.5 3.2 2 2 1 3 3 3 0 Prefoldin subunit TMPIT PF07851.13 KUM65744.1 - 1.8 7.7 5.3 1.4 8.1 0.8 2.2 3 0 0 3 3 3 0 TMPIT-like protein Prefoldin_2 PF01920.20 KUM65744.1 - 2.2 8.3 11.3 1.2 9.1 1.7 3.4 2 1 1 3 3 3 0 Prefoldin subunit HIP1_clath_bdg PF16515.5 KUM65744.1 - 3.1 8.5 15.4 0.19 12.3 4.4 2.8 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tropomyosin_1 PF12718.7 KUM65744.1 - 3.3 7.9 14.8 6.8 6.8 14.8 1.6 1 0 0 1 1 1 0 Tropomyosin like RRP36 PF06102.12 KUM65744.1 - 3.5 7.5 10.1 2.6 8.0 2.3 2.5 2 1 0 2 2 2 0 rRNA biogenesis protein RRP36 Lebercilin PF15619.6 KUM65744.1 - 4 7.1 21.0 2.9 7.5 4.9 3.1 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 KUM65744.1 - 4.1 7.5 6.0 1.3 9.1 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 KUM65744.1 - 4.5 8.0 10.8 4.1 8.1 0.3 3.2 3 1 0 3 3 2 0 Initiation control protein YabA Atg14 PF10186.9 KUM65744.1 - 5.2 6.1 9.8 10 5.1 9.8 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KUM65744.1 - 6 5.7 16.6 3 6.6 4.2 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein Swi5 PF07061.11 KUM65744.1 - 7.5 6.7 9.0 20 5.3 0.1 3.7 3 1 1 4 4 4 0 Swi5 ATG16 PF08614.11 KUM65744.1 - 8.5 6.6 20.2 18 5.5 5.3 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) S4 PF01479.25 KUM65745.1 - 2e-12 46.6 0.5 2e-12 46.6 0.5 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.18 KUM65746.1 - 5.7e-46 154.5 4.0 5.7e-46 154.5 4.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e CEP1-DNA_bind PF09287.10 KUM65746.1 - 0.063 12.9 0.2 0.073 12.7 0.2 1.2 1 0 0 1 1 1 0 CEP-1, DNA binding WD40 PF00400.32 KUM65747.1 - 7.8e-41 137.3 18.6 6.4e-06 26.8 0.7 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM65747.1 - 9.8e-06 25.8 2.4 6.3 7.2 0.1 5.0 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KUM65747.1 - 2.3e-05 23.3 7.3 0.83 8.2 0.0 5.2 4 2 1 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KUM65747.1 - 7.7e-05 21.6 1.2 0.4 9.4 0.0 4.3 2 1 1 4 4 4 1 Nup133 N terminal like DUF5046 PF16465.5 KUM65747.1 - 0.00012 21.7 0.4 9.9 5.5 0.0 4.7 2 2 4 6 6 6 1 Domain of unknown function (DUF5046) Hira PF07569.11 KUM65747.1 - 0.0021 17.8 1.7 0.57 9.9 0.2 2.4 2 0 0 2 2 2 2 TUP1-like enhancer of split PALB2_WD40 PF16756.5 KUM65747.1 - 0.0043 16.0 2.4 3.7 6.4 0.0 4.2 2 1 2 4 4 4 1 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 KUM65747.1 - 0.0078 15.8 4.7 1.8 8.1 0.3 3.0 1 1 1 3 3 3 2 PQQ-like domain CPSF_A PF03178.15 KUM65747.1 - 0.016 14.5 0.1 0.062 12.6 0.0 1.9 2 0 0 2 2 2 0 CPSF A subunit region PQQ_3 PF13570.6 KUM65747.1 - 0.036 14.6 3.1 14 6.4 0.0 4.4 5 0 0 5 5 4 0 PQQ-like domain LppA PF16708.5 KUM65747.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium GRDP-like PF07173.12 KUM65748.1 - 6.2e-18 65.8 0.0 8.1e-15 55.7 0.0 2.5 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Perm-CXXC PF15629.6 KUM65748.1 - 0.06 13.6 0.4 0.16 12.2 0.4 1.7 1 0 0 1 1 1 0 Permuted single zf-CXXC unit Ras PF00071.22 KUM65749.1 - 3.5e-47 160.0 0.0 4.4e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM65749.1 - 3.2e-18 66.1 0.0 5.5e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM65749.1 - 3.8e-09 36.2 0.0 5.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KUM65749.1 - 0.0077 15.6 0.0 0.0096 15.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KUM65749.1 - 0.016 14.6 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KUM65749.1 - 0.1 11.7 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit PCI PF01399.27 KUM65750.1 - 3.6e-19 69.2 0.1 9.2e-19 67.9 0.1 1.7 1 0 0 1 1 1 1 PCI domain Putative_PNPOx PF01243.20 KUM65751.1 - 6.8e-13 48.6 0.0 1.8e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KUM65751.1 - 0.006 16.6 0.0 0.014 15.4 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase BPL_LplA_LipB PF03099.19 KUM65752.1 - 1e-05 25.5 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DJ-1_PfpI PF01965.24 KUM65754.1 - 3.3e-16 59.5 0.0 4.2e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 KUM65754.1 - 0.021 14.6 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Peptidase_C65 PF10275.9 KUM65755.1 - 1.9e-27 96.3 0.0 2.3e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain Peptidase_C65 PF10275.9 KUM65756.1 - 4.3e-20 72.2 0.0 5.2e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Sugar_tr PF00083.24 KUM65757.1 - 5.7e-119 397.9 17.6 9.7e-119 397.2 17.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM65757.1 - 2.3e-23 82.7 64.7 3.6e-18 65.6 34.8 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM65757.1 - 0.00018 20.1 1.5 0.00018 20.1 1.5 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) LMWPc PF01451.21 KUM65758.1 - 0.17 12.2 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Low molecular weight phosphotyrosine protein phosphatase RRM_1 PF00076.22 KUM65759.1 - 4.3e-05 23.2 0.0 7.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CHC2 PF01807.20 KUM65760.1 - 0.053 13.3 0.2 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 CHC2 zinc finger zf-C2HE PF16278.5 KUM65760.1 - 0.12 12.9 8.5 0.19 12.2 0.0 3.0 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_Tnp_IS91 PF14319.6 KUM65760.1 - 0.56 10.3 9.1 0.16 12.0 5.5 1.9 2 0 0 2 2 2 0 Transposase zinc-binding domain Semialdhyde_dhC PF02774.18 KUM65761.1 - 9.8e-35 120.3 0.0 1.4e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KUM65761.1 - 4.2e-30 104.7 0.0 1.1e-29 103.4 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KUM65761.1 - 0.031 14.5 0.0 0.2 11.9 0.0 2.2 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Ribosomal_S4e PF00900.20 KUM65762.1 - 9.3e-38 128.0 0.1 1.8e-37 127.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KUM65762.1 - 1e-24 85.9 0.0 1.7e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KUM65762.1 - 8.5e-17 61.0 5.8 1.6e-16 60.1 5.8 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KUM65762.1 - 3e-07 30.0 0.0 5.5e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KUM65762.1 - 0.0029 17.5 1.9 0.0029 17.5 1.9 2.9 3 0 0 3 3 3 1 KOW motif RasGEF PF00617.19 KUM65763.1 - 6.8e-07 29.7 0.2 3e-06 27.5 0.0 2.1 3 0 0 3 3 3 1 RasGEF domain Myb_DNA-bind_6 PF13921.6 KUM65765.1 - 1.4e-17 63.7 0.0 5.9e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KUM65765.1 - 4.3e-15 55.6 0.3 4.1e-08 33.3 0.1 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 KUM65765.1 - 0.00054 20.0 0.0 0.33 11.0 0.0 2.4 2 0 0 2 2 2 2 SLIDE Nop16 PF09420.10 KUM65765.1 - 0.08 13.0 0.1 5.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 PX PF00787.24 KUM65766.1 - 2.2e-26 92.1 0.2 2.6e-26 91.8 0.2 1.1 1 0 0 1 1 1 1 PX domain WD40 PF00400.32 KUM65767.1 - 4.1e-17 62.2 19.5 0.00088 20.0 0.4 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 KUM65767.1 - 0.00018 20.2 3.1 0.28 9.7 0.0 4.0 3 1 2 5 5 5 3 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 KUM65767.1 - 0.084 13.2 0.1 2.4 8.5 0.0 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PPARgamma_N PF12577.8 KUM65767.1 - 0.11 13.1 3.5 17 6.1 1.2 3.0 2 1 0 2 2 2 0 PPAR gamma N-terminal region Nup160 PF11715.8 KUM65767.1 - 0.14 10.8 0.0 0.25 9.9 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KUM65767.1 - 0.15 12.6 2.7 5.2 7.7 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain SecE PF00584.20 KUM65768.1 - 2.3e-15 56.2 0.0 2.9e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CDP-OH_P_transf PF01066.21 KUM65769.1 - 9.3e-18 64.8 0.1 9.3e-18 64.8 0.1 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NIPSNAP PF07978.13 KUM65770.1 - 2.9e-41 139.9 0.3 2.1e-28 98.5 0.1 2.4 2 0 0 2 2 2 2 NIPSNAP FSH1 PF03959.13 KUM65771.1 - 4.5e-17 62.4 0.0 5.4e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Ribosomal_S27e PF01667.17 KUM65773.1 - 9.9e-29 98.8 6.7 1.3e-28 98.5 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2HC5 PF06221.13 KUM65773.1 - 0.29 11.2 6.3 2 8.4 4.2 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type MFS_1 PF07690.16 KUM65775.1 - 9.3e-23 80.7 24.8 9.3e-23 80.7 24.8 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM65775.1 - 0.005 15.8 32.2 0.11 11.3 32.2 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter Phage_holin_7_1 PF16081.5 KUM65775.1 - 0.017 15.3 8.6 0.11 12.6 0.4 3.2 2 1 1 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family OATP PF03137.20 KUM65775.1 - 0.55 8.5 16.1 0.18 10.0 2.8 2.6 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF5336 PF17270.2 KUM65775.1 - 8.4 6.0 8.6 1.6 8.4 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5336) UPF0016 PF01169.19 KUM65776.1 - 4.8e-41 138.9 25.8 7.8e-21 74.2 10.5 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Presenilin PF01080.17 KUM65776.1 - 0.076 11.8 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Presenilin SPX PF03105.19 KUM65776.1 - 0.098 12.6 6.5 0.2 11.6 6.5 1.5 1 1 0 1 1 1 0 SPX domain DUF3357 PF11837.8 KUM65776.1 - 1.9 9.0 5.4 13 6.3 0.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) DUF3446 PF11928.8 KUM65776.1 - 4.8 7.5 12.5 0.84 10.0 3.7 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain MFS_1 PF07690.16 KUM65777.1 - 5.1e-35 121.0 27.4 5.1e-35 121.0 27.4 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM65777.1 - 2.4e-15 56.4 3.7 2.4e-15 56.4 3.7 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KUM65777.1 - 0.00064 18.3 4.1 0.00098 17.7 4.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FA_desaturase PF00487.24 KUM65777.1 - 3.6 7.3 19.8 5.6 6.7 1.0 3.5 2 2 1 3 3 3 0 Fatty acid desaturase Myb_DNA-binding PF00249.31 KUM65778.1 - 3e-06 27.3 0.0 6.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KUM65778.1 - 0.014 15.7 0.0 0.038 14.2 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KUM65778.1 - 0.74 10.2 6.3 1.6 9.1 2.0 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain WSC PF01822.19 KUM65779.1 - 2.3e-15 56.6 10.8 4.7e-15 55.6 10.8 1.5 1 0 0 1 1 1 1 WSC domain F-box-like PF12937.7 KUM65781.1 - 0.00017 21.4 2.3 0.00019 21.3 0.1 2.2 2 0 0 2 2 2 1 F-box-like Rhomboid_SP PF12595.8 KUM65781.1 - 0.0042 16.5 0.2 0.0073 15.7 0.2 1.3 1 0 0 1 1 1 1 Rhomboid serine protease F-box PF00646.33 KUM65781.1 - 0.01 15.7 0.6 0.021 14.7 0.0 1.8 2 0 0 2 2 2 0 F-box domain DUF3807 PF12720.7 KUM65782.1 - 2.4 8.4 12.7 0.93 9.7 4.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Ribosomal_S15 PF00312.22 KUM65783.1 - 2e-26 92.0 0.2 8.5e-26 90.0 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_S2 PF00318.20 KUM65784.1 - 3e-25 88.7 0.1 3.9e-15 55.7 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KUM65784.1 - 2.1e-08 35.4 11.9 4.4e-08 34.4 11.9 1.6 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus PseudoU_synth_1 PF01416.20 KUM65785.1 - 2.4e-34 118.1 0.0 1.1e-32 112.6 0.0 2.7 3 0 0 3 3 3 1 tRNA pseudouridine synthase PIG-H PF10181.9 KUM65786.1 - 2.6e-25 88.1 0.1 4.6e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component XPG_I PF00867.18 KUM65788.1 - 5.1e-24 84.4 0.1 3.3e-23 81.9 0.0 2.4 3 0 0 3 3 3 1 XPG I-region GEN1_C PF18380.1 KUM65788.1 - 1.2e-19 71.1 0.0 1.2e-19 71.1 0.0 2.5 2 1 1 3 3 3 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 KUM65788.1 - 1.9e-06 28.3 0.0 4.3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Gag_p12 PF01141.18 KUM65788.1 - 0.0038 17.5 0.8 0.0038 17.5 0.8 2.7 3 0 0 3 3 3 1 Gag polyprotein, inner coat protein p12 adh_short PF00106.25 KUM65791.1 - 4.4e-14 52.4 0.0 8.5e-14 51.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM65791.1 - 3.4e-12 46.4 0.0 3.8e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM65791.1 - 0.00065 19.6 0.0 0.0051 16.7 0.0 2.0 1 1 0 1 1 1 1 KR domain F-box PF00646.33 KUM65792.1 - 0.00073 19.4 0.0 0.0021 17.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain Pribosyl_synth PF14572.6 KUM65793.1 - 1.2e-38 132.9 1.8 4.3e-33 114.9 0.5 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KUM65793.1 - 6.2e-33 113.2 0.0 1.4e-32 112.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KUM65793.1 - 2.3e-13 50.0 0.2 4e-13 49.2 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KUM65793.1 - 0.014 14.8 0.2 0.024 14.1 0.2 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase MFS_1 PF07690.16 KUM65794.1 - 1.1e-13 50.9 19.7 1.2e-13 50.7 19.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM65794.1 - 2.4e-06 26.7 11.0 3.2e-06 26.3 11.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KUM65794.1 - 0.046 12.6 5.4 0.24 10.2 5.4 2.0 1 1 0 1 1 1 0 MFS_1 like family vATP-synt_AC39 PF01992.16 KUM65796.1 - 4.3e-105 351.9 0.0 4.9e-105 351.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit HAD_2 PF13419.6 KUM65797.1 - 6.1e-24 85.1 0.0 7.5e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KUM65797.1 - 1.5e-12 48.2 0.9 5.5e-11 43.2 0.9 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KUM65797.1 - 4e-10 40.4 0.0 5.5e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KUM65797.1 - 1.2e-08 34.9 0.0 2.9e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KUM65797.1 - 1.4e-05 25.1 0.1 0.0016 18.5 0.0 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KUM65797.1 - 0.089 12.5 0.1 0.76 9.5 0.0 2.2 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase RNA_pol_Rpb4 PF03874.16 KUM65798.1 - 1.8e-05 25.1 0.0 0.11 12.8 0.0 2.4 2 1 0 2 2 2 2 RNA polymerase Rpb4 Nop PF01798.18 KUM65799.1 - 9.8e-83 277.1 0.0 2.1e-82 276.0 0.0 1.6 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KUM65799.1 - 3.1e-23 81.9 2.4 3.1e-23 81.9 2.4 2.7 2 0 0 2 2 2 1 NOP5NT (NUC127) domain APH PF01636.23 KUM65801.1 - 7.3e-12 45.7 0.0 2.8e-11 43.8 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KUM65801.1 - 0.0038 16.1 0.0 1.2 7.9 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 KUM65801.1 - 0.081 12.1 0.0 1.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase PP-binding PF00550.25 KUM65802.1 - 1.2e-06 28.8 0.1 2.7e-06 27.6 0.1 1.7 1 1 0 1 1 1 1 Phosphopantetheine attachment site Aldo_ket_red PF00248.21 KUM65803.1 - 6.4e-38 130.6 0.0 1.2e-35 123.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KUM65804.1 - 8.6e-12 44.8 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family APH PF01636.23 KUM65805.1 - 1.7e-10 41.2 0.0 0.00019 21.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KUM65805.1 - 8.7e-10 38.3 0.0 2.2e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KUM65805.1 - 2.8e-08 33.4 0.0 3.9e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KUM65805.1 - 0.0059 15.4 0.0 0.0079 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KUM65805.1 - 0.0068 15.7 0.0 0.0083 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KUM65805.1 - 0.0074 15.9 0.1 0.41 10.2 0.0 2.4 3 0 0 3 3 3 1 RIO1 family AP_endonuc_2 PF01261.24 KUM65805.1 - 0.048 13.1 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Zn_clus PF00172.18 KUM65806.1 - 1.8e-09 37.6 8.1 4.4e-09 36.3 8.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoiA PF06054.11 KUM65806.1 - 0.022 13.9 1.0 0.035 13.2 0.0 1.7 2 0 0 2 2 2 0 Competence protein CoiA-like family RNA_pol_Rpb1_1 PF04997.12 KUM65807.1 - 6.2e-85 285.3 0.2 1.1e-84 284.5 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KUM65807.1 - 1.9e-79 266.9 0.2 2.8e-79 266.3 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KUM65807.1 - 4.4e-72 241.7 0.0 1.3e-71 240.2 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KUM65807.1 - 9.7e-34 116.6 0.0 3.3e-32 111.6 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KUM65807.1 - 2.1e-27 95.2 0.1 5.8e-27 93.8 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rpr2 PF04032.16 KUM65807.1 - 2.1 8.7 5.0 1.3 9.4 1.9 2.3 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GTP_EFTU PF00009.27 KUM65808.1 - 6.1e-50 169.5 0.0 9e-50 168.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KUM65808.1 - 4.1e-43 145.9 3.4 7e-43 145.2 3.4 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KUM65808.1 - 6.8e-19 67.7 0.0 1.6e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 KUM65808.1 - 2.7e-05 24.2 0.0 6.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 KUM65808.1 - 0.0005 20.1 0.0 0.0013 18.7 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 KUM65808.1 - 0.00066 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Ras family GTP_EFTU_D2 PF03144.25 KUM65808.1 - 0.00079 19.8 0.1 0.002 18.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 KUM65808.1 - 0.011 15.2 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RF3_C PF16658.5 KUM65808.1 - 0.018 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Roc PF08477.13 KUM65808.1 - 0.16 12.2 0.0 0.6 10.3 0.0 2.0 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Snurportin1 PF11538.8 KUM65808.1 - 0.23 11.7 2.3 0.58 10.4 2.3 1.6 1 0 0 1 1 1 0 Snurportin1 HORMA PF02301.18 KUM65809.1 - 4.8e-34 117.8 0.1 5.6e-34 117.6 0.1 1.0 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 KUM65809.1 - 0.035 14.0 0.1 0.077 12.8 0.0 1.6 2 0 0 2 2 2 0 Bacterial HORMA domain 2 Ras PF00071.22 KUM65812.1 - 5.7e-12 45.5 0.0 2.4e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KUM65812.1 - 0.00038 20.6 0.0 0.0017 18.6 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KUM65812.1 - 0.0014 17.9 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit NACHT PF05729.12 KUM65812.1 - 0.0069 16.3 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KUM65812.1 - 0.0088 16.4 0.0 0.011 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KUM65812.1 - 0.009 16.3 0.0 0.026 14.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KUM65812.1 - 0.027 14.2 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KUM65812.1 - 0.035 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.21 KUM65812.1 - 0.055 12.9 0.0 0.15 11.5 0.0 1.8 1 1 0 1 1 1 0 ADP-ribosylation factor family RNA_helicase PF00910.22 KUM65812.1 - 0.064 13.7 0.0 0.32 11.4 0.0 2.0 1 1 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KUM65812.1 - 0.12 12.9 0.1 0.24 11.9 0.1 1.4 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KUM65812.1 - 0.15 11.9 0.0 0.55 10.1 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase MCM PF00493.23 KUM65812.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.3 1 1 0 1 1 1 0 MCM P-loop domain DEAD PF00270.29 KUM65813.1 - 2.2e-37 128.5 0.0 6.2e-37 127.0 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM65813.1 - 8.4e-23 80.8 0.0 2.6e-22 79.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KUM65813.1 - 2e-22 79.1 0.1 3.9e-22 78.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KUM65813.1 - 0.0035 17.4 1.8 0.02 14.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KUM65813.1 - 0.084 12.1 0.0 0.084 12.1 0.0 2.5 2 1 1 3 3 3 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 KUM65813.1 - 0.098 12.9 0.1 1.5 9.1 0.1 2.7 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KUM65813.1 - 0.34 10.4 9.8 3.6 7.0 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Snurportin1 PF11538.8 KUM65813.1 - 2.1 8.6 13.6 0.14 12.3 0.9 2.7 2 0 0 2 2 2 0 Snurportin1 CTP_transf_1 PF01148.20 KUM65814.1 - 5e-05 23.2 1.6 7.2e-05 22.7 1.6 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Yip1 PF04893.17 KUM65815.1 - 0.0084 15.8 5.6 0.05 13.3 3.0 2.3 1 1 0 2 2 2 2 Yip1 domain zf-CCCH_4 PF18044.1 KUM65816.1 - 1.4e-07 31.1 3.1 2.3e-07 30.4 3.1 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KUM65816.1 - 2.4e-07 30.6 6.2 4.2e-07 29.8 6.2 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KUM65816.1 - 7.2e-05 22.6 1.1 0.00012 21.8 1.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KUM65816.1 - 0.00079 20.1 0.2 0.0029 18.3 0.2 2.0 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 KUM65816.1 - 0.0069 16.8 2.9 0.012 16.0 2.9 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KUM65816.1 - 0.012 15.8 0.2 0.028 14.6 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger containing family Sec1 PF00995.23 KUM65819.1 - 2e-128 430.2 0.0 2.3e-128 430.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF1199 PF06712.11 KUM65823.1 - 0.15 12.1 0.0 16 5.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) Band_7 PF01145.25 KUM65824.1 - 3.2e-26 92.4 1.9 5.2e-26 91.7 1.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KUM65824.1 - 0.11 12.2 0.3 0.17 11.6 0.3 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family TerB_C PF15615.6 KUM65826.1 - 0.039 14.2 4.6 1.9 8.8 0.1 3.2 3 1 1 4 4 4 0 TerB-C domain 2CSK_N PF08521.10 KUM65826.1 - 0.051 13.7 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal COG5 PF10392.9 KUM65826.1 - 0.061 13.5 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 Golgi transport complex subunit 5 SKG6 PF08693.10 KUM65827.1 - 2.5e-05 23.6 0.6 6e-05 22.4 0.6 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 KUM65827.1 - 0.22 11.5 2.6 0.61 10.1 0.7 2.5 1 1 1 2 2 2 0 LPXTG cell wall anchor motif Methyltransf_2 PF00891.18 KUM65828.1 - 1.3e-20 73.6 0.0 2.7e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Bac_luciferase PF00296.20 KUM65830.1 - 2.9e-58 197.8 0.5 4.2e-58 197.2 0.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase HNH_repeat PF18780.1 KUM65830.1 - 0.082 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Homing endonuclease repeat FMO-like PF00743.19 KUM65831.1 - 1.8e-16 59.7 0.1 2e-13 49.6 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KUM65831.1 - 4.1e-11 42.9 0.0 1.2e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM65831.1 - 2.7e-09 36.7 0.0 3.1e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM65831.1 - 1.4e-05 24.5 0.6 6.4e-05 22.4 0.2 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM65831.1 - 0.00075 18.7 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 KUM65831.1 - 0.015 14.7 0.0 0.1 11.9 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 KUM65831.1 - 0.047 12.9 0.1 0.13 11.5 0.1 1.6 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KUM65831.1 - 0.056 13.4 0.4 0.46 10.5 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF736 PF05284.12 KUM65831.1 - 0.065 13.1 0.0 0.25 11.2 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF736) DAO PF01266.24 KUM65831.1 - 0.092 12.3 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Acetyltransf_1 PF00583.25 KUM65832.1 - 7.6e-08 32.6 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KUM65832.1 - 1.7e-06 28.4 0.0 2.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KUM65832.1 - 9e-06 25.6 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KUM65832.1 - 0.0013 18.6 0.0 0.0032 17.4 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KUM65832.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Actin PF00022.19 KUM65833.1 - 4.1e-20 71.8 0.0 5.5e-13 48.3 0.0 2.5 2 1 0 2 2 2 2 Actin CENP-L PF13092.6 KUM65834.1 - 8.4e-47 159.4 0.1 1.1e-46 159.0 0.1 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 HNH_2 PF13391.6 KUM65835.1 - 0.029 14.5 0.0 0.097 12.8 0.0 1.9 2 0 0 2 2 2 0 HNH endonuclease KR PF08659.10 KUM65836.1 - 5e-24 85.2 0.0 9.4e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 KUM65836.1 - 3e-16 60.7 0.0 3.3e-15 57.3 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KUM65836.1 - 1.5e-14 54.1 0.0 3.3e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KUM65836.1 - 8.7e-09 35.1 0.0 9e-08 31.8 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM65836.1 - 5e-05 23.0 0.0 0.00014 21.5 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KUM65836.1 - 0.00013 21.9 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.25 KUM65836.1 - 0.0042 16.5 0.1 0.0078 15.7 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NmrA PF05368.13 KUM65836.1 - 0.078 12.5 0.1 4.7 6.7 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family ELFV_dehydrog PF00208.21 KUM65836.1 - 0.16 11.7 0.0 2.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PS-DH PF14765.6 KUM65837.1 - 3.7e-40 138.0 0.0 4.9e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KUM65837.1 - 1.5e-14 54.3 0.0 2.1e-13 50.5 0.0 2.2 1 1 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.12 KUM65837.1 - 8.4e-13 48.9 0.0 3.8e-12 46.8 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM65837.1 - 4.8e-09 36.3 0.0 1.1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM65837.1 - 3.9e-08 33.9 0.1 1.3e-07 32.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM65837.1 - 2.1e-07 31.5 0.0 8.4e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM65837.1 - 9.4e-07 28.7 0.0 2.8e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM65837.1 - 7.5e-05 22.2 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KUM65837.1 - 0.049 13.2 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 KUM65837.1 - 0.051 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ketoacyl-synt PF00109.26 KUM65838.1 - 9.9e-61 205.5 0.1 1.6e-60 204.8 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KUM65838.1 - 4.9e-40 136.2 0.5 2.8e-39 133.8 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KUM65838.1 - 5e-19 69.0 0.0 6.7e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain KAsynt_C_assoc PF16197.5 KUM65838.1 - 2.6e-13 50.4 0.0 1e-12 48.5 0.0 2.0 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KUM65838.1 - 4.2e-05 23.0 0.3 9.7e-05 21.8 0.3 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KUM65838.1 - 0.15 12.0 0.2 0.39 10.6 0.2 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III E1-E2_ATPase PF00122.20 KUM65839.1 - 1e-18 67.5 0.0 3.7e-18 65.7 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KUM65839.1 - 7.5e-13 49.2 2.7 1.1e-06 29.1 1.6 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KUM65839.1 - 0.0004 20.4 0.0 0.013 15.5 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KUM65839.1 - 0.031 14.0 0.1 0.096 12.4 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PKD_channel PF08016.12 KUM65841.1 - 1.7e-06 27.0 20.3 3.9e-05 22.5 19.8 2.5 1 1 0 1 1 1 1 Polycystin cation channel EIF_2_alpha PF07541.12 KUM65842.1 - 2.7e-37 127.4 0.0 5.2e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KUM65842.1 - 7.7e-13 48.6 0.6 1.9e-12 47.4 0.6 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Sulfate_transp PF00916.20 KUM65843.1 - 6.1e-70 235.9 17.8 8.2e-70 235.5 17.8 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KUM65843.1 - 6.2e-15 54.9 0.0 1.3e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KUM65843.1 - 0.00021 21.5 0.0 0.0011 19.2 0.0 2.2 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 KUM65843.1 - 3.2 8.2 16.9 0.75 10.2 5.7 2.8 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily FF PF01846.19 KUM65844.1 - 1e-11 44.8 6.5 6e-10 39.2 0.2 2.9 3 0 0 3 3 3 2 FF domain VGLL4 PF15245.6 KUM65844.1 - 0.034 14.2 0.4 0.071 13.2 0.4 1.5 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Trypsin_2 PF13365.6 KUM65846.1 - 0.0044 17.9 0.0 0.01 16.7 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain GFO_IDH_MocA PF01408.22 KUM65847.1 - 2.3e-19 70.4 0.0 2.1e-17 64.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KUM65847.1 - 1.3e-06 28.4 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KUM65847.1 - 0.0025 18.5 0.0 0.008 16.8 0.0 1.9 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 KUM65847.1 - 0.026 14.9 0.0 0.064 13.6 0.0 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KUM65848.1 - 2.5e-69 234.3 15.6 1.8e-57 195.2 2.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KUM65848.1 - 1.1e-28 100.2 15.4 1.7e-28 99.6 15.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KUM65848.1 - 1.6 9.3 9.8 0.3 11.7 1.4 3.2 3 0 0 3 3 3 0 Phage holin family 2 NAD_binding_10 PF13460.6 KUM65849.1 - 1.7e-08 34.6 0.0 2.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KUM65849.1 - 3.9e-07 29.8 0.0 5.9e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.10 KUM65849.1 - 1.8e-05 24.3 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 HIM1 Semialdhyde_dh PF01118.24 KUM65849.1 - 6.5e-05 23.4 0.1 0.00028 21.3 0.1 2.0 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KUM65849.1 - 0.0016 18.1 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KUM65849.1 - 0.0059 15.8 0.1 1.1 8.4 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KUM65849.1 - 0.018 14.1 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TraC PF07820.12 KUM65849.1 - 0.055 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 TraC-like protein DUF1471 PF07338.13 KUM65849.1 - 0.063 13.3 0.3 0.12 12.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Ldh_1_N PF00056.23 KUM65849.1 - 0.089 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain SHE3 PF17078.5 KUM65851.1 - 0.0029 17.4 2.4 0.0036 17.0 2.4 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Ribosomal_L26 PF16906.5 KUM65851.1 - 0.035 14.6 0.1 0.05 14.1 0.1 1.3 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal MYO10_CC PF16735.5 KUM65851.1 - 0.052 13.7 0.9 0.052 13.7 0.9 2.3 1 1 2 3 3 3 0 Unconventional myosin-X coiled coil domain Proteasome PF00227.26 KUM65853.1 - 1.4e-61 207.3 0.2 1.7e-61 207.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KUM65853.1 - 2.9e-13 49.2 0.1 8.9e-13 47.7 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 KUM65853.1 - 0.016 15.3 0.4 0.049 13.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 KUM65853.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Cellulase PF00150.18 KUM65854.1 - 3.2e-14 53.0 3.6 3.2e-14 53.0 3.6 1.8 1 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Radical_SAM PF04055.21 KUM65854.1 - 0.012 16.0 0.0 0.3 11.4 0.0 2.2 2 0 0 2 2 2 0 Radical SAM superfamily DUF3886 PF13025.6 KUM65854.1 - 5.6 7.2 25.8 0.21 11.8 5.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) TPP_enzyme_N PF02776.18 KUM65856.1 - 8.6e-42 142.7 0.1 1.6e-40 138.5 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KUM65856.1 - 4.1e-22 78.6 0.1 4.8e-21 75.1 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KUM65856.1 - 1.5e-06 27.9 0.0 5.3e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Peptidase_S78_2 PF14550.6 KUM65856.1 - 0.081 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative phage serine protease XkdF XFP_N PF09364.10 KUM65856.1 - 0.24 10.2 0.6 0.38 9.5 0.6 1.2 1 0 0 1 1 1 0 XFP N-terminal domain HATPase_c PF02518.26 KUM65857.1 - 4.9e-17 62.4 0.0 1.2e-16 61.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KUM65857.1 - 4e-14 52.7 0.0 1.2e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KUM65857.1 - 2.5e-12 46.7 0.9 6.4e-12 45.3 0.9 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PHY PF00360.20 KUM65857.1 - 1.1e-06 28.1 0.0 3.8e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Phytochrome region PAS_2 PF08446.11 KUM65857.1 - 0.0019 18.8 0.0 0.0054 17.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold GAF PF01590.26 KUM65857.1 - 0.0026 18.4 0.0 0.0086 16.7 0.0 1.9 1 0 0 1 1 1 1 GAF domain DUF4993 PF16384.5 KUM65857.1 - 0.12 11.3 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function HATPase_c_3 PF13589.6 KUM65857.1 - 0.16 11.8 0.0 0.4 10.5 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SNF2_N PF00176.23 KUM65858.1 - 9.8e-67 225.1 0.3 5.7e-65 219.3 0.3 2.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KUM65858.1 - 5.8e-16 58.8 0.0 2.3e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM65858.1 - 1.3e-07 31.8 0.1 1.3e-07 31.8 0.1 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit BUD22 PF09073.10 KUM65858.1 - 0.0029 17.0 21.0 0.0029 17.0 21.0 2.7 2 0 0 2 2 2 2 BUD22 MH2 PF03166.14 KUM65858.1 - 0.076 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 MH2 domain SDA1 PF05285.12 KUM65858.1 - 0.22 10.9 38.6 0.15 11.5 21.6 2.6 2 0 0 2 2 2 0 SDA1 SIR2 PF02146.17 KUM65859.1 - 1.6e-38 132.4 0.0 8.6e-38 130.0 0.0 1.9 1 1 0 1 1 1 1 Sir2 family Ribosomal_L6 PF00347.23 KUM65861.1 - 4.5e-21 75.3 0.0 2.2e-09 37.9 0.0 2.7 2 1 0 2 2 2 2 Ribosomal protein L6 Inositol_P PF00459.25 KUM65862.1 - 1.3e-50 172.4 0.3 2.2e-50 171.7 0.3 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.16 KUM65863.1 - 1.3e-41 142.7 47.6 1.3e-41 142.7 47.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM65863.1 - 2.6e-16 59.5 11.3 2.6e-16 59.5 11.3 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter Phage_holin_3_2 PF04550.12 KUM65863.1 - 8.6 7.0 11.5 18 6.0 0.1 3.6 3 0 0 3 3 3 0 Phage holin family 2 Tannase PF07519.11 KUM65864.1 - 9.2e-123 410.6 0.8 1.1e-122 410.3 0.8 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KUM65864.1 - 0.0014 17.9 0.0 0.029 13.6 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KUM65864.1 - 0.0043 16.5 0.3 0.053 13.0 0.3 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KUM65864.1 - 0.021 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold BDM PF10684.9 KUM65864.1 - 0.18 12.2 0.1 0.5 10.8 0.0 1.7 2 0 0 2 2 2 0 Putative biofilm-dependent modulation protein MFS_1 PF07690.16 KUM65866.1 - 6.6e-17 61.5 46.0 6.6e-17 61.5 46.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3043 PF11241.8 KUM65866.1 - 1.4 8.9 3.9 0.86 9.6 1.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) VHS PF00790.19 KUM65867.1 - 9.4e-25 87.1 0.0 2e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain ENTH PF01417.20 KUM65867.1 - 0.0005 20.1 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 ENTH domain GAT PF03127.14 KUM65867.1 - 0.0061 16.8 0.1 0.013 15.8 0.1 1.7 1 0 0 1 1 1 1 GAT domain Dexa_ind PF15198.6 KUM65867.1 - 0.011 15.8 0.2 0.34 11.0 0.1 2.4 2 0 0 2 2 2 0 Dexamethasone-induced DUF4598 PF15370.6 KUM65867.1 - 0.034 14.6 0.4 0.081 13.4 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) Abhydrolase_6 PF12697.7 KUM65869.1 - 3.7e-05 24.4 0.0 5.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM65869.1 - 0.00025 20.8 0.2 0.29 10.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.25 KUM65869.1 - 0.00025 20.9 0.1 0.00039 20.3 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KUM65869.1 - 0.00038 19.8 0.0 0.0047 16.2 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KUM65869.1 - 0.00076 19.0 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF818 PF05677.12 KUM65869.1 - 0.0028 16.7 0.0 0.0038 16.2 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 KUM65869.1 - 0.011 15.6 0.0 3.9 7.2 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase fn3 PF00041.21 KUM65869.1 - 0.071 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain LIDHydrolase PF10230.9 KUM65869.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase YdjM PF04307.14 KUM65869.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Flavoprotein PF02441.19 KUM65870.1 - 1.8e-12 47.3 0.0 3e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein DUF1391 PF07151.12 KUM65870.1 - 3.5 7.5 7.1 0.1 12.4 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1391) FAD_binding_1 PF00667.20 KUM65871.1 - 2.8e-62 210.2 0.0 5.1e-62 209.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KUM65871.1 - 2.8e-09 37.6 0.0 7.9e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 KUM65871.1 - 4.8e-09 36.5 0.4 1.3e-08 35.1 0.4 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 KUM65871.1 - 5.3e-06 26.7 0.1 1.3e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KUM65871.1 - 0.0014 18.5 0.9 0.0044 16.9 0.1 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain FtsJ PF01728.19 KUM65872.1 - 9.1e-63 211.6 0.0 1.2e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Aldo_ket_red PF00248.21 KUM65873.1 - 3.5e-48 164.3 0.0 2.3e-46 158.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Sof1 PF04158.14 KUM65873.1 - 0.15 12.3 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 Sof1-like domain Acyl-CoA_dh_1 PF00441.24 KUM65874.1 - 1.4e-32 113.0 0.5 2.5e-32 112.2 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KUM65874.1 - 4.5e-23 81.3 0.1 7.5e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KUM65874.1 - 2.2e-16 60.5 0.2 1.2e-15 58.2 0.0 2.3 2 2 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KUM65874.1 - 1.1e-05 25.7 0.3 1.8e-05 25.0 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DEAD PF00270.29 KUM65875.1 - 1.5e-44 151.9 0.1 2.6e-44 151.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM65875.1 - 2.8e-27 95.3 0.1 3e-26 91.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KUM65875.1 - 0.011 16.0 0.3 0.036 14.3 0.3 2.0 1 1 0 1 1 1 0 AAA domain Zip PF02535.22 KUM65875.1 - 0.076 12.2 2.1 0.13 11.5 2.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Dynactin_p62 PF05502.13 KUM65875.1 - 0.11 11.3 3.1 0.23 10.2 3.1 1.4 1 0 0 1 1 1 0 Dynactin p62 family GCN5L1 PF06320.13 KUM65875.1 - 0.34 11.1 0.1 0.34 11.1 0.1 3.3 4 0 0 4 4 4 0 GCN5-like protein 1 (GCN5L1) Presenilin PF01080.17 KUM65875.1 - 1.8 7.3 8.2 3.1 6.5 8.2 1.4 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 KUM65875.1 - 2.2 7.0 9.4 4.8 5.9 9.4 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Neur_chan_memb PF02932.16 KUM65875.1 - 3.4 7.7 4.9 2 8.4 2.5 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF1688 PF07958.11 KUM65876.1 - 3.1e-166 553.3 0.0 3.4e-166 553.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) FMO-like PF00743.19 KUM65878.1 - 3.3e-25 88.5 0.0 3.6e-18 65.3 0.0 3.3 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KUM65878.1 - 2.5e-22 79.5 0.0 2.1e-20 73.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM65878.1 - 4.9e-16 58.8 0.0 3.5e-13 49.4 0.0 2.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM65878.1 - 7.6e-09 36.0 0.6 0.0048 17.4 0.1 3.9 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KUM65878.1 - 1.8e-08 34.0 0.1 0.0015 17.8 0.1 3.1 3 0 0 3 3 3 2 FAD binding domain K_oxygenase PF13434.6 KUM65878.1 - 4.7e-08 32.6 0.1 2e-06 27.2 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KUM65878.1 - 3.8e-07 30.2 0.0 0.0016 18.7 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KUM65878.1 - 9.1e-05 22.0 0.0 0.28 10.5 0.0 3.3 4 0 0 4 4 4 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KUM65878.1 - 0.00011 21.6 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 KUM65878.1 - 0.00048 19.4 0.0 0.68 9.1 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 KUM65878.1 - 0.0006 19.5 1.6 0.51 9.9 0.3 3.7 2 2 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KUM65878.1 - 0.0019 17.4 0.0 0.14 11.2 0.0 2.5 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KUM65878.1 - 0.0035 17.3 1.2 15 5.6 1.7 3.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KUM65878.1 - 0.0058 15.7 0.0 0.059 12.4 0.0 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.14 KUM65878.1 - 0.0072 15.1 0.0 0.85 8.2 0.0 2.9 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 KUM65881.1 - 8.9e-29 101.2 0.1 1.1e-28 100.9 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KUM65881.1 - 0.0021 18.6 1.5 0.0053 17.3 1.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM65881.1 - 0.012 14.8 0.2 0.033 13.4 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM65881.1 - 0.031 13.4 0.1 0.048 12.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 KUM65881.1 - 0.066 12.4 0.3 0.12 11.6 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KUM65881.1 - 0.24 11.2 0.4 0.39 10.6 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PTR2 PF00854.21 KUM65882.1 - 4.6e-74 249.6 6.9 9.1e-74 248.6 6.9 1.5 1 1 0 1 1 1 1 POT family Abhydrolase_3 PF07859.13 KUM65883.1 - 3e-54 184.1 0.0 3.9e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KUM65883.1 - 2.3e-06 26.8 0.2 6.4e-06 25.3 0.2 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KUM65883.1 - 0.0004 19.9 0.0 0.013 15.0 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KUM65883.1 - 0.028 13.9 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Gpi16 PF04113.14 KUM65884.1 - 1.1e-245 816.5 0.0 1.3e-245 816.2 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.15 KUM65886.1 - 3.4e-39 135.0 1.3 3.9e-39 134.8 1.3 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DegS PF05384.11 KUM65886.1 - 0.019 14.5 1.6 0.54 9.7 0.1 2.2 1 1 1 2 2 2 0 Sensor protein DegS TelA PF05816.11 KUM65886.1 - 0.023 13.8 0.4 0.032 13.3 0.4 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) MCPsignal PF00015.21 KUM65886.1 - 0.027 14.3 0.1 0.044 13.6 0.1 1.3 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.6 KUM65886.1 - 0.039 14.3 2.0 0.065 13.6 2.0 1.4 1 0 0 1 1 1 0 Syntaxin-like protein HMG_box_5 PF14887.6 KUM65886.1 - 0.066 13.2 0.0 0.19 11.7 0.0 1.8 1 1 1 2 2 2 0 HMG (high mobility group) box 5 Prefoldin PF02996.17 KUM65886.1 - 0.27 11.1 1.4 2.3 8.1 0.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit GRP PF07172.11 KUM65886.1 - 1.5 9.5 13.6 2.2 9.0 11.6 2.0 2 0 0 2 2 2 0 Glycine rich protein family XhlA PF10779.9 KUM65886.1 - 1.6 9.0 4.4 2.3 8.5 0.6 2.2 2 0 0 2 2 2 0 Haemolysin XhlA SPOC PF07744.13 KUM65888.1 - 1.7e-23 83.2 0.0 2.8e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KUM65888.1 - 3.1e-23 82.4 1.2 3.1e-23 82.4 1.2 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KUM65888.1 - 2.9e-10 39.9 12.3 5.1e-10 39.1 12.3 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 KUM65888.1 - 0.037 14.4 0.4 0.037 14.4 0.4 3.0 3 0 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.6 KUM65888.1 - 0.042 13.4 5.8 0.074 12.6 5.8 1.4 1 0 0 1 1 1 0 PHD-finger APG12 PF04110.13 KUM65889.1 - 3.4e-29 101.1 0.0 6.8e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KUM65889.1 - 0.0051 17.0 0.0 0.0067 16.6 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.15 KUM65890.1 - 5.8e-109 363.5 1.3 7e-109 363.2 1.3 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KUM65890.1 - 3.3e-07 30.0 0.2 6.9e-07 29.0 0.1 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 KUM65890.1 - 0.00054 19.0 0.0 0.00076 18.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4861) UQ_con PF00179.26 KUM65891.1 - 4.5e-32 110.6 0.2 5.6e-32 110.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ank_2 PF12796.7 KUM65892.1 - 8.9e-37 125.6 2.0 2.2e-12 47.4 0.0 8.6 8 2 0 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM65892.1 - 4.2e-31 106.9 1.2 1.7e-05 25.3 0.0 11.1 9 2 2 11 11 11 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM65892.1 - 4.3e-22 77.9 4.0 0.015 15.6 0.0 10.3 9 1 0 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM65892.1 - 1.2e-21 74.4 10.5 0.02 15.4 0.0 11.9 12 0 0 12 12 12 5 Ankyrin repeat Ank PF00023.30 KUM65892.1 - 2.6e-16 59.3 17.7 0.00034 20.9 0.0 10.6 12 0 0 12 12 12 4 Ankyrin repeat Pyridox_ox_2 PF12900.7 KUM65893.1 - 2.1e-36 125.0 0.0 2.7e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M24 PF00557.24 KUM65894.1 - 8.9e-51 172.5 0.0 1.3e-50 172.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KUM65894.1 - 1e-36 125.4 0.0 2e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RuBisCO_large PF00016.20 KUM65894.1 - 0.025 13.8 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Creatinase_N PF01321.18 KUM65894.1 - 0.17 12.5 0.0 1.2 9.8 0.0 2.2 1 1 0 1 1 1 0 Creatinase/Prolidase N-terminal domain Tht1 PF04163.12 KUM65895.1 - 0.0012 17.8 11.2 0.0012 17.8 11.2 2.0 2 1 0 2 2 2 1 Tht1-like nuclear fusion protein Baculo_PEP_C PF04513.12 KUM65895.1 - 0.0058 16.7 5.8 0.0058 16.7 5.8 2.5 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4305 PF14146.6 KUM65895.1 - 0.06 13.5 0.5 0.58 10.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4305) RNA_polI_A14 PF08203.11 KUM65895.1 - 0.27 12.0 3.3 1.2 9.9 3.3 2.1 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 ROS_MUCR PF05443.11 KUM65895.1 - 0.59 10.2 9.1 0.32 11.0 0.2 3.1 3 0 0 3 3 3 0 ROS/MUCR transcriptional regulator protein DUF2011 PF09428.10 KUM65897.1 - 2e-32 111.3 0.6 1.9e-31 108.1 0.0 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) DUF2058 PF09831.9 KUM65897.1 - 1.6 8.8 10.8 4.3 7.5 10.8 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) LAMTOR PF15454.6 KUM65898.1 - 5e-20 71.9 0.1 9.9e-20 70.9 0.1 1.5 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator SVIP PF15811.5 KUM65898.1 - 0.17 12.3 0.9 0.58 10.6 0.1 2.1 2 0 0 2 2 2 0 Small VCP/p97-interacting protein Dfp1_Him1_M PF08630.10 KUM65900.1 - 1.5e-40 138.4 0.0 4.8e-40 136.7 0.0 1.9 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 KUM65900.1 - 6.6e-21 74.2 0.1 1.4e-20 73.1 0.1 1.6 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 KUM65900.1 - 0.014 15.4 0.0 0.045 13.7 0.0 1.9 2 0 0 2 2 2 0 twin BRCT domain CCDC53 PF10152.9 KUM65901.1 - 0.021 15.3 8.0 0.041 14.3 1.3 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex MFS_1 PF07690.16 KUM65903.1 - 6.6e-38 130.5 54.8 1.1e-36 126.6 54.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Pyridox_oxase_2 PF12766.7 KUM65905.1 - 3.4e-28 98.2 0.0 5.9e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Nucleo_P87 PF07267.11 KUM65906.1 - 0.3 9.9 4.4 0.32 9.8 4.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nnf1 PF03980.14 KUM65906.1 - 0.47 10.8 3.8 0.31 11.5 0.8 2.1 1 1 1 2 2 2 0 Nnf1 MFS_1 PF07690.16 KUM65907.1 - 1.5e-30 106.3 28.0 1.9e-30 106.0 28.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KUM65907.1 - 0.00035 20.0 3.8 0.00035 20.0 3.8 1.9 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB GMC_oxred_N PF00732.19 KUM65908.1 - 1.2e-66 225.1 0.2 1.4e-66 224.8 0.2 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM65908.1 - 4.3e-33 114.9 0.0 7.9e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KUM65908.1 - 5.4e-06 25.8 0.0 0.018 14.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KUM65908.1 - 5.5e-05 22.5 0.1 0.0032 16.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM65908.1 - 6.9e-05 22.6 0.2 0.006 16.2 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KUM65908.1 - 8.9e-05 21.9 0.2 0.33 10.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM65908.1 - 0.00019 21.6 0.3 0.00062 20.0 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KUM65908.1 - 0.00021 20.2 0.4 0.013 14.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KUM65908.1 - 0.00073 18.7 0.0 0.0016 17.6 0.0 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KUM65908.1 - 0.0042 16.4 0.4 0.014 14.6 0.1 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KUM65908.1 - 0.011 15.7 2.6 0.22 11.5 0.1 2.9 2 1 1 3 3 3 0 FAD-NAD(P)-binding YmdB PF13277.6 KUM65908.1 - 0.033 13.5 0.0 0.075 12.4 0.0 1.5 1 0 0 1 1 1 0 YmdB-like protein TrkA_N PF02254.18 KUM65908.1 - 0.08 13.2 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 KUM65908.1 - 0.087 13.4 0.1 0.51 10.9 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aminotran_1_2 PF00155.21 KUM65909.1 - 1.6e-10 40.7 0.0 4e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II zf-C2H2_jaz PF12171.8 KUM65911.1 - 0.056 13.8 0.5 0.056 13.8 0.5 3.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding CXCR4_N PF12109.8 KUM65911.1 - 0.15 12.3 0.6 0.46 10.7 0.6 1.9 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal FOXP-CC PF16159.5 KUM65912.1 - 0.0049 17.5 1.2 0.0049 17.5 1.2 2.9 2 1 1 3 3 3 1 FOXP coiled-coil domain zf-C2H2 PF00096.26 KUM65912.1 - 0.013 15.9 26.0 0.23 12.0 1.5 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF629 PF04780.12 KUM65912.1 - 0.12 10.9 4.6 0.2 10.1 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) ORC3_N PF07034.11 KUM65913.1 - 2.6e-39 135.3 0.0 1.2e-37 129.7 0.0 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KUM65913.1 - 7.8e-23 81.1 0.7 1.6e-14 54.1 0.0 2.9 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal YihI PF04220.12 KUM65913.1 - 0.068 12.9 2.1 6.5 6.5 0.2 2.5 2 0 0 2 2 2 0 Der GTPase activator (YihI) PPR_2 PF13041.6 KUM65914.1 - 1.4e-05 25.2 0.1 1.1 9.5 0.0 5.2 6 0 0 6 6 6 2 PPR repeat family Ku_PK_bind PF08785.11 KUM65914.1 - 0.11 12.6 0.2 0.37 10.9 0.2 1.9 1 0 0 1 1 1 0 Ku C terminal domain like TPR_14 PF13428.6 KUM65914.1 - 0.43 11.5 4.6 0.81 10.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Nop14 PF04147.12 KUM65915.1 - 3.5e-291 968.5 35.1 4.2e-291 968.3 35.1 1.0 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.13 KUM65915.1 - 0.051 12.8 0.1 0.13 11.5 0.1 1.6 1 0 0 1 1 1 0 Noc2p family Pro-rich_19 PF15455.6 KUM65915.1 - 0.054 12.6 0.7 0.18 10.9 0.7 1.9 1 0 0 1 1 1 0 Proline-rich 19 HEAT_2 PF13646.6 KUM65916.1 - 0.0013 19.1 1.0 0.0055 17.1 0.8 2.2 2 1 1 3 3 3 1 HEAT repeats PPR_1 PF12854.7 KUM65916.1 - 0.3 10.8 0.8 0.61 9.8 0.8 1.4 1 0 0 1 1 1 0 PPR repeat Sec66 PF09802.9 KUM65919.1 - 4.5e-83 277.2 0.8 5.5e-83 277.0 0.8 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Tcp11 PF05794.13 KUM65919.1 - 1.7 7.6 7.6 0.75 8.8 3.4 1.9 1 1 1 2 2 2 0 T-complex protein 11 TPPII_N PF12583.8 KUM65919.1 - 6.9 7.3 10.0 15 6.1 10.0 1.6 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal AAA PF00004.29 KUM65920.1 - 5.6e-49 165.9 0.0 9.6e-42 142.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KUM65920.1 - 3.9e-10 39.4 0.1 1.2e-09 37.8 0.0 1.9 2 0 0 2 2 1 1 AAA+ lid domain IstB_IS21 PF01695.17 KUM65920.1 - 1.2e-07 31.6 0.0 1.2e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KUM65920.1 - 3.1e-06 27.4 0.0 1e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KUM65920.1 - 4.3e-06 27.2 2.9 8.4e-05 23.0 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KUM65920.1 - 6e-05 23.1 0.0 0.0018 18.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Bromodomain PF00439.25 KUM65920.1 - 0.0012 18.8 0.0 0.0037 17.3 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Sigma54_activ_2 PF14532.6 KUM65920.1 - 0.0016 18.6 0.0 0.7 10.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 KUM65920.1 - 0.0022 18.3 0.2 0.069 13.4 0.1 3.2 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KUM65920.1 - 0.0026 18.1 0.0 0.0079 16.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 KUM65920.1 - 0.0039 16.9 0.0 0.0089 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KUM65920.1 - 0.015 14.7 0.1 0.17 11.3 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KUM65920.1 - 0.016 15.0 0.0 0.075 12.8 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KUM65920.1 - 0.018 15.1 0.0 0.067 13.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KUM65920.1 - 0.019 14.5 0.0 0.053 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KUM65920.1 - 0.021 14.1 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 KUM65920.1 - 0.03 14.5 0.0 0.11 12.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KUM65920.1 - 0.033 14.7 0.0 0.12 12.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KUM65920.1 - 0.046 13.4 0.0 1.1 8.9 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KUM65920.1 - 0.061 12.4 0.0 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KUM65920.1 - 0.075 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 KUM65920.1 - 0.12 12.4 0.0 0.47 10.4 0.0 2.0 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KUM65920.1 - 0.12 12.9 0.3 0.45 11.0 0.0 2.1 2 0 0 2 2 1 0 ABC transporter AAA_3 PF07726.11 KUM65920.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KUM65920.1 - 0.25 11.1 0.0 0.25 11.1 0.0 3.8 4 0 0 4 4 2 0 AAA domain Pro_CA PF00484.19 KUM65921.1 - 7.5e-51 172.5 0.0 1.1e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase GDA1_CD39 PF01150.17 KUM65922.1 - 1.6e-105 353.2 0.0 2.3e-105 352.7 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ammonium_transp PF00909.21 KUM65923.1 - 2.8e-112 375.3 25.5 3.3e-112 375.1 25.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family LRR_9 PF14580.6 KUM65925.1 - 2.2e-61 206.4 0.1 3.3e-61 205.8 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KUM65925.1 - 2.1e-07 30.6 3.2 8e-07 28.7 3.2 2.1 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KUM65925.1 - 2.7e-05 24.4 9.2 0.025 15.0 3.7 3.4 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) Gp-FAR-1 PF05823.12 KUM65925.1 - 0.023 15.1 0.1 0.034 14.5 0.1 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4349 PF14257.6 KUM65925.1 - 0.15 11.5 2.7 0.35 10.3 2.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) LRR_1 PF00560.33 KUM65925.1 - 6 7.8 5.8 1.7e+02 3.4 0.0 4.3 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 KUM65925.1 - 8.6 6.7 8.9 13 6.2 0.3 4.4 5 0 0 5 5 5 0 Leucine Rich repeat FAD_binding_4 PF01565.23 KUM65926.1 - 3.1e-20 72.3 0.6 5.5e-20 71.5 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain HET PF06985.11 KUM65928.1 - 4.4e-09 36.8 0.1 1.5e-06 28.6 0.0 2.9 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Peptidase_S41 PF03572.18 KUM65930.1 - 7.5e-07 28.9 0.0 7.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S41 SNF2_N PF00176.23 KUM65932.1 - 2e-41 141.9 0.1 7.9e-41 139.9 0.1 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KUM65932.1 - 2.6e-13 50.3 0.1 1.2e-12 48.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KUM65932.1 - 1.1e-06 28.5 7.1 1.9e-06 27.7 7.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 KUM65932.1 - 6.9e-06 26.2 0.0 3.8e-05 23.8 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 KUM65932.1 - 0.00031 20.5 4.8 0.00057 19.7 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KUM65932.1 - 0.0072 16.3 2.4 0.017 15.2 2.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KUM65932.1 - 0.009 15.9 5.3 0.03 14.2 5.3 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KUM65932.1 - 0.018 15.3 6.6 0.037 14.3 6.6 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KUM65932.1 - 0.047 13.5 4.1 0.11 12.3 4.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM65932.1 - 0.14 12.1 6.0 0.34 10.8 6.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KUM65932.1 - 0.35 11.0 3.6 0.9 9.7 3.6 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 IBR PF01485.21 KUM65932.1 - 0.35 11.1 3.6 0.37 11.0 1.6 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 KUM65932.1 - 0.8 9.6 6.5 1.7 8.5 6.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-CRD PF17979.1 KUM65932.1 - 0.91 9.6 4.6 2.7 8.1 3.9 2.1 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions DZR PF12773.7 KUM65932.1 - 3.2 7.9 6.4 27 4.9 6.3 2.2 1 1 1 2 2 2 0 Double zinc ribbon RSN1_7TM PF02714.15 KUM65933.1 - 1.1e-90 303.7 22.4 1.1e-90 303.7 22.4 2.8 3 0 0 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KUM65933.1 - 9.8e-45 152.1 3.3 9.8e-45 152.1 3.3 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KUM65933.1 - 1.8e-35 122.8 0.3 2.6e-35 122.2 0.3 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KUM65933.1 - 3.3e-32 110.5 0.4 1.7e-31 108.2 0.2 2.1 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DUF679 PF05078.12 KUM65933.1 - 0.053 13.5 0.5 0.21 11.5 0.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF679) MCM PF00493.23 KUM65935.1 - 3e-97 324.1 0.0 4.3e-97 323.6 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KUM65935.1 - 2.7e-39 133.9 0.2 5.6e-39 132.9 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KUM65935.1 - 1.7e-25 89.3 0.2 1.6e-24 86.2 0.2 2.6 1 1 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KUM65935.1 - 5.5e-25 87.6 0.2 1.9e-24 85.9 0.2 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KUM65935.1 - 8.4e-17 61.7 1.2 2.7e-16 60.0 0.1 2.4 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 KUM65935.1 - 4.8e-05 22.8 0.0 0.0002 20.8 0.0 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KUM65935.1 - 0.0042 17.1 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KUM65935.1 - 0.0044 16.9 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KUM65935.1 - 0.01 15.5 0.0 0.027 14.2 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain GIDA_assoc PF13932.6 KUM65935.1 - 0.081 13.1 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 GidA associated domain E1-E2_ATPase PF00122.20 KUM65936.1 - 4.1e-46 156.8 3.8 9.9e-46 155.5 3.8 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KUM65936.1 - 3.2e-21 76.6 0.0 6.6e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KUM65936.1 - 7.4e-07 29.5 0.3 3e-06 27.6 0.1 2.2 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KUM65936.1 - 0.00014 21.7 0.9 0.0052 16.6 0.3 2.5 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase SNF2_N PF00176.23 KUM65939.1 - 5.6e-35 120.7 0.1 1.4e-33 116.1 0.1 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KUM65939.1 - 1.5e-11 44.6 0.0 3.6e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KUM65939.1 - 0.0028 17.5 6.9 0.0061 16.4 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 KUM65939.1 - 0.049 12.8 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4_2 PF13923.6 KUM65939.1 - 0.058 13.2 2.6 0.17 11.7 2.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KUM65939.1 - 0.06 13.2 6.5 0.43 10.5 6.8 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KUM65939.1 - 0.17 11.9 8.9 0.45 10.5 8.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KUM65939.1 - 0.28 11.1 9.8 0.18 11.7 7.7 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-CRD PF17979.1 KUM65939.1 - 0.99 9.5 4.3 0.37 10.9 0.6 2.2 3 0 0 3 3 3 0 Cysteine rich domain with multizinc binding regions zf-RING_UBOX PF13445.6 KUM65939.1 - 1.5 8.9 6.6 5.3 7.2 6.6 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KUM65939.1 - 5.2 7.5 9.2 15 6.0 9.2 1.8 1 0 0 1 1 1 0 Ring finger domain PRMT5_C PF17286.2 KUM65941.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 PRMT5 oligomerisation domain G-patch PF01585.23 KUM65943.1 - 2e-06 27.6 1.3 4.3e-05 23.3 1.3 2.5 1 1 0 1 1 1 1 G-patch domain DUF4187 PF13821.6 KUM65943.1 - 0.00028 20.6 0.2 0.00069 19.3 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ALMT PF11744.8 KUM65943.1 - 1.3 7.8 2.5 2.4 6.9 2.5 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter DbpA PF03880.15 KUM65945.1 - 0.018 15.0 0.1 0.056 13.4 0.1 1.8 2 0 0 2 2 2 0 DbpA RNA binding domain COesterase PF00135.28 KUM65946.1 - 4.5e-19 68.7 0.0 5.1e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 KUM65947.1 - 1.8e-51 175.6 0.1 2.2e-51 175.3 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KUM65947.1 - 0.037 13.9 0.0 0.099 12.5 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold ERF PF04404.12 KUM65948.1 - 0.025 14.4 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 ERF superfamily Aminotran_5 PF00266.19 KUM65949.1 - 1.2e-46 159.4 0.0 1.5e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KUM65949.1 - 0.0028 16.2 0.0 0.0046 15.5 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_11 PF00457.17 KUM65950.1 - 2.3e-74 248.8 19.2 2.7e-74 248.6 19.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Putative_PNPOx PF01243.20 KUM65953.1 - 0.0095 16.1 0.0 0.023 14.9 0.0 1.7 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DUF1772 PF08592.11 KUM65954.1 - 6.2e-30 104.3 4.5 8.1e-30 103.9 4.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) MFS_1 PF07690.16 KUM65955.1 - 2e-39 135.5 50.8 2e-39 135.5 50.8 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM65955.1 - 3.3e-16 58.8 20.2 7.7e-16 57.6 20.2 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KUM65955.1 - 0.063 11.6 8.0 0.073 11.3 1.9 2.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FMO-like PF00743.19 KUM65956.1 - 2.3e-35 122.1 0.0 7.9e-20 70.8 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KUM65956.1 - 1.2e-15 57.6 0.0 2.4e-11 43.4 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM65956.1 - 1.1e-12 47.8 0.1 3.5e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM65956.1 - 1.7e-09 37.9 0.0 1.1e-08 35.2 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KUM65956.1 - 1.2e-08 35.0 2.3 0.00062 19.4 2.3 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KUM65956.1 - 3.4e-07 30.7 0.1 0.0004 20.9 0.5 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM65956.1 - 6.2e-07 28.9 0.9 6.5e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KUM65956.1 - 7.6e-06 26.1 0.0 3.7e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KUM65956.1 - 0.00046 20.3 0.0 0.039 14.0 0.1 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thioredoxin_11 PF18078.1 KUM65956.1 - 0.0011 19.1 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like SNTX domain AlaDh_PNT_C PF01262.21 KUM65956.1 - 0.002 17.5 0.2 0.012 14.9 0.3 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KUM65956.1 - 0.0057 15.4 1.1 0.024 13.3 0.6 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KUM65956.1 - 0.026 13.8 1.1 0.048 12.9 1.1 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KUM65956.1 - 0.029 13.6 1.6 0.049 12.9 0.4 2.0 3 0 0 3 3 3 0 Thi4 family Amino_oxidase PF01593.24 KUM65956.1 - 0.077 12.3 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 KUM65956.1 - 0.15 12.5 0.1 9.7 6.7 0.2 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KUM65956.1 - 0.16 11.8 0.4 0.35 10.7 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.19 KUM65957.1 - 2.3e-35 122.0 0.0 2.5e-18 65.8 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KUM65957.1 - 3.8e-13 49.4 0.1 3.8e-09 36.2 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM65957.1 - 1.6e-12 47.3 0.0 1.9e-11 43.7 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM65957.1 - 8.9e-08 32.1 1.4 0.001 18.8 1.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KUM65957.1 - 7.5e-07 28.6 0.4 0.0016 17.7 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KUM65957.1 - 1.5e-06 28.4 0.0 4e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KUM65957.1 - 0.00025 21.0 2.4 0.016 15.2 2.5 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KUM65957.1 - 0.0038 17.8 2.0 0.0078 16.8 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KUM65957.1 - 0.0042 16.7 0.1 0.096 12.3 0.0 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KUM65957.1 - 0.0093 14.7 0.5 0.015 14.0 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.18 KUM65957.1 - 0.015 15.2 0.6 0.027 14.4 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KUM65957.1 - 0.017 14.3 0.3 0.033 13.3 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 KUM65957.1 - 0.029 13.7 1.8 0.051 12.9 0.4 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KUM65957.1 - 0.041 13.9 0.2 2.1 8.4 0.1 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KUM65957.1 - 0.043 13.1 0.2 0.088 12.0 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KUM65957.1 - 0.047 12.9 0.4 0.1 11.8 0.1 1.6 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 KUM65957.1 - 0.049 13.0 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KUM65957.1 - 0.22 10.6 1.1 0.35 9.9 1.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Semialdhyde_dh PF01118.24 KUM65957.1 - 0.25 11.8 0.8 0.89 10.0 0.0 2.2 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KUM65958.1 - 4.9e-14 52.4 0.0 8.6e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4265 PF14085.6 KUM65958.1 - 0.025 14.6 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) ADH_N PF08240.12 KUM65958.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Metallophos PF00149.28 KUM65959.1 - 4.5e-06 27.3 0.9 8e-06 26.5 0.3 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KUM65959.1 - 0.054 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Amidase PF01425.21 KUM65961.1 - 2.1e-117 392.9 0.4 2.5e-117 392.6 0.4 1.0 1 0 0 1 1 1 1 Amidase bZIP_2 PF07716.15 KUM65962.1 - 1.6e-11 44.1 15.4 1.6e-11 44.1 15.4 2.4 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 KUM65962.1 - 3.5e-07 30.2 16.5 6.3e-07 29.4 16.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KUM65962.1 - 0.0011 19.4 13.7 0.0011 19.4 13.7 1.6 2 0 0 2 2 2 1 bZIP Maf transcription factor FPP PF05911.11 KUM65962.1 - 0.0029 15.9 5.7 0.004 15.4 5.7 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil APG6_N PF17675.1 KUM65962.1 - 0.23 12.0 11.8 0.39 11.2 11.8 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region CENP-H PF05837.12 KUM65962.1 - 1.1 9.7 9.9 2.2 8.7 9.9 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Bystin PF05291.11 KUM65963.1 - 5e-130 433.0 0.0 6.5e-130 432.7 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF2207 PF09972.9 KUM65964.1 - 0.61 8.8 9.3 0.13 11.0 5.7 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Snf7 PF03357.21 KUM65965.1 - 0.028 14.0 8.9 0.038 13.6 8.9 1.1 1 0 0 1 1 1 0 Snf7 Zn_clus PF00172.18 KUM65966.1 - 1.5e-06 28.2 8.6 2.5e-06 27.5 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YrhK PF14145.6 KUM65967.1 - 1.3 9.0 22.8 1.1 9.1 2.2 4.2 4 1 0 4 4 4 0 YrhK-like protein SnoaL_2 PF12680.7 KUM65968.1 - 0.0017 18.9 0.0 0.0091 16.6 0.0 2.1 2 0 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 KUM65968.1 - 0.044 13.6 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase MFS_1 PF07690.16 KUM65969.1 - 9.4e-41 139.9 57.9 1.2e-40 139.6 56.0 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM65969.1 - 4.1e-10 39.1 10.7 4.1e-10 39.1 10.7 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter DUF5305 PF17231.2 KUM65969.1 - 0.24 10.8 0.5 2.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5305) MFS_1 PF07690.16 KUM65970.1 - 4.8e-19 68.5 10.0 4.8e-19 68.5 10.0 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM65970.1 - 2.3e-09 36.6 3.6 2.3e-09 36.6 3.6 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter TMEM208_SND2 PF05620.11 KUM65970.1 - 1 9.1 2.9 1.2 8.8 0.0 2.6 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 MFS_1 PF07690.16 KUM65971.1 - 2.8e-34 118.6 30.9 2.8e-34 118.6 30.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2417 PF10329.9 KUM65971.1 - 1.8 7.9 4.1 3.9 6.8 0.5 3.1 4 0 0 4 4 4 0 Region of unknown function (DUF2417) Phage_holin_2_1 PF04971.12 KUM65971.1 - 3.6 7.7 5.3 54 3.9 2.0 3.3 3 0 0 3 3 3 0 Bacteriophage P21 holin S GDC-P PF02347.16 KUM65972.1 - 9.1e-173 575.0 0.0 4.8e-161 536.4 0.0 2.3 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KUM65972.1 - 0.00012 21.5 0.2 0.00025 20.5 0.2 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KUM65972.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Amidohydro_1 PF01979.20 KUM65973.1 - 5e-61 206.9 0.0 6.3e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KUM65973.1 - 2.8e-05 23.8 1.9 0.0019 17.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family RhgB_N PF09284.10 KUM65974.1 - 1.8e-107 358.6 4.0 1.8e-107 358.6 4.0 1.6 2 0 0 2 2 2 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KUM65974.1 - 3.8e-44 150.5 0.1 1.5e-43 148.6 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KUM65974.1 - 3.3e-23 81.3 7.5 3.3e-23 81.3 7.5 3.3 4 0 0 4 4 4 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KUM65974.1 - 0.0008 19.6 1.1 0.0008 19.6 1.1 3.7 4 0 0 4 4 4 1 Carboxypeptidase regulatory-like domain DUF5011 PF16403.5 KUM65974.1 - 9.1 6.5 8.7 2.1 8.5 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5011) NAD_binding_2 PF03446.15 KUM65975.1 - 4.1e-14 53.0 0.1 8.5e-14 52.0 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KUM65975.1 - 3.2e-08 34.1 0.0 1.5e-07 31.9 0.1 2.2 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KUM65975.1 - 8.7e-06 25.8 0.0 1.8e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KUM65975.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KUM65975.1 - 0.0015 18.5 0.0 0.0043 17.0 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 KUM65975.1 - 0.013 15.0 0.1 0.34 10.4 0.0 2.6 2 1 0 2 2 2 0 short chain dehydrogenase NAD_Gly3P_dh_N PF01210.23 KUM65975.1 - 0.014 15.3 0.1 0.038 14.0 0.1 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.12 KUM65975.1 - 0.025 14.2 0.0 0.068 12.7 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 KUM65975.1 - 0.028 14.1 0.1 0.052 13.2 0.1 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF5610 PF18433.1 KUM65975.1 - 0.058 13.9 0.2 0.9 10.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5610) IF-2B PF01008.17 KUM65977.1 - 3e-74 249.8 4.4 3.4e-74 249.6 4.4 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Rad60-SLD PF11976.8 KUM65979.1 - 1.1e-20 73.2 0.2 4.4e-18 64.9 0.5 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KUM65979.1 - 0.00058 19.6 0.0 0.023 14.4 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family LSM PF01423.22 KUM65980.1 - 7.8e-17 60.7 0.1 9.8e-17 60.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KUM65980.1 - 0.00081 19.5 0.0 0.00093 19.3 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KUM65980.1 - 0.0063 16.6 0.1 0.0071 16.4 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain N-SET PF11764.8 KUM65981.1 - 2.3e-56 190.6 1.7 2.3e-56 190.6 1.7 2.1 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KUM65981.1 - 3e-26 90.8 0.8 8.6e-26 89.4 0.8 1.8 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 KUM65981.1 - 1.5e-20 74.3 3.1 1.1e-19 71.5 0.2 3.4 3 0 0 3 3 3 1 SET domain RRM_1 PF00076.22 KUM65981.1 - 0.0014 18.4 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trm112p PF03966.16 KUM65982.1 - 2.7e-15 56.7 0.1 3.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.6 KUM65982.1 - 0.1 13.1 0.6 0.19 12.3 0.6 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain CBX7_C PF17218.3 KUM65982.1 - 0.11 12.3 1.8 0.19 11.5 1.8 1.4 1 0 0 1 1 1 0 CBX family C-terminal motif Fcf1 PF04900.12 KUM65983.1 - 3.3e-36 123.7 0.2 4.7e-36 123.2 0.2 1.2 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KUM65983.1 - 4.3e-11 43.2 0.0 6.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 PIN like domain XPG_I_2 PF12813.7 KUM65984.1 - 6.6e-82 274.7 0.0 9.2e-82 274.3 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 KUM65984.1 - 0.027 14.8 0.1 0.066 13.6 0.1 1.6 1 0 0 1 1 1 0 XPG I-region zf-C2H2 PF00096.26 KUM65985.1 - 0.0033 17.8 1.1 0.0088 16.4 1.1 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.7 KUM65985.1 - 0.0053 17.1 0.4 0.0092 16.3 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KUM65985.1 - 0.048 14.0 2.2 0.081 13.2 2.2 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KUM65985.1 - 0.27 12.2 0.5 0.27 12.2 0.5 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger Transket_pyr PF02779.24 KUM65986.1 - 1.7e-46 158.2 0.0 2.9e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KUM65986.1 - 2.6e-36 124.2 0.1 2.5e-35 121.0 0.0 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain FAS_I_H PF18314.1 KUM65987.1 - 5.8e-78 261.2 0.0 5.8e-78 261.2 0.0 2.3 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KUM65987.1 - 1.4e-76 256.3 0.0 3.1e-76 255.2 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KUM65987.1 - 8.3e-23 81.3 0.1 1.8e-22 80.2 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KUM65987.1 - 5.4e-17 62.0 0.0 1.4e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KUM65987.1 - 1.2e-11 44.7 0.4 3.7e-11 43.1 0.0 2.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 KUM65987.1 - 0.00066 19.6 0.0 0.0027 17.7 0.0 2.0 1 0 0 1 1 1 1 KR domain DUF1729 PF08354.10 KUM65988.1 - 7.2e-160 531.7 0.0 1.2e-159 531.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KUM65988.1 - 1.4e-91 307.4 0.0 6.1e-90 301.9 0.0 3.1 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 KUM65988.1 - 4.9e-52 175.6 0.0 1.8e-51 173.8 0.0 2.1 2 0 0 2 2 2 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 KUM65988.1 - 7.4e-43 145.6 0.0 1.9e-42 144.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 KUM65988.1 - 1.4e-38 131.2 0.0 3.6e-38 129.9 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 KUM65988.1 - 9.3e-38 130.3 0.2 3.5e-37 128.4 0.0 2.1 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 KUM65988.1 - 1.7e-21 76.7 0.0 6.2e-21 74.9 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.15 KUM65988.1 - 0.26 10.7 1.2 1.6 8.1 1.1 2.2 1 1 0 1 1 1 0 Nitronate monooxygenase TRM PF02005.16 KUM65989.1 - 4.1e-116 388.2 0.0 1.4e-99 333.9 0.0 2.2 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase DUF2067 PF09840.9 KUM65989.1 - 0.00014 21.5 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2067) Met_10 PF02475.16 KUM65989.1 - 0.00018 21.3 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 KUM65989.1 - 0.011 16.5 0.0 0.022 15.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KUM65989.1 - 0.035 13.9 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KUM65989.1 - 0.038 13.4 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Trypan_PARP PF05887.11 KUM65989.1 - 7.3 6.6 15.1 0.083 12.9 2.7 2.8 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) DUF1691 PF07950.11 KUM65990.1 - 1.6e-40 138.2 7.9 1.3e-33 115.9 4.9 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) DUF383 PF04063.14 KUM65991.1 - 3.1e-69 232.5 0.5 5.4e-68 228.4 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KUM65991.1 - 2.7e-23 81.6 3.9 3.7e-23 81.1 1.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF384) OPT PF03169.15 KUM65992.1 - 1.7e-199 664.5 39.7 1.9e-199 664.3 39.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TFIIF_alpha PF05793.12 KUM65994.1 - 3.8e-09 35.7 53.7 9.4e-09 34.4 5.0 3.1 1 1 3 4 4 4 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3982 PF13138.6 KUM65994.1 - 3.3 7.6 5.7 0.77 9.6 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3982) adh_short_C2 PF13561.6 KUM65995.1 - 2.1e-62 210.8 0.0 2.6e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM65995.1 - 1.4e-56 191.1 0.7 1.7e-56 190.8 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM65995.1 - 4.9e-08 33.1 0.2 1.1e-07 31.9 0.2 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM65995.1 - 0.0088 15.5 0.4 0.017 14.6 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KUM65995.1 - 0.0095 15.3 0.2 0.019 14.3 0.2 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PPS_PS PF02006.16 KUM65995.1 - 0.021 14.4 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase Peptidase_S10 PF00450.22 KUM65996.1 - 3.9e-92 309.8 0.0 5e-92 309.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.16 KUM65997.1 - 1.1e-35 123.2 26.5 1.1e-35 123.2 26.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KUM65997.1 - 0.00032 20.4 0.9 0.00088 19.0 0.9 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DALR_2 PF09190.11 KUM65998.1 - 0.075 13.5 0.0 18 5.9 0.0 2.5 2 0 0 2 2 2 0 DALR domain CoA_trans PF01144.23 KUM66000.1 - 1.5e-99 331.8 0.9 4.7e-61 205.9 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KUM66000.1 - 0.002 18.1 0.1 0.0039 17.1 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain VanW PF04294.13 KUM66000.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 VanW like protein p450 PF00067.22 KUM66001.1 - 1.1e-73 248.6 0.0 1.3e-73 248.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KUM66002.1 - 2e-29 102.7 27.5 8.4e-15 54.5 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KUM66002.1 - 3.2e-05 23.0 20.3 0.0039 16.1 11.2 2.1 1 1 1 2 2 2 2 MFS_1 like family ATG22 PF11700.8 KUM66002.1 - 2.1 6.9 17.7 0.25 9.9 7.4 3.4 2 2 0 3 3 3 0 Vacuole effluxer Atg22 like Sugar_tr PF00083.24 KUM66002.1 - 3.4 6.4 27.4 20 3.9 27.4 2.8 1 1 0 1 1 1 0 Sugar (and other) transporter Mid2 PF04478.12 KUM66003.1 - 0.00076 19.3 0.1 0.0013 18.6 0.1 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Amnionless PF14828.6 KUM66003.1 - 0.17 10.6 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless NAD_binding_1 PF00175.21 KUM66004.1 - 5.4e-34 117.1 0.0 1.2e-33 116.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KUM66004.1 - 6.7e-28 97.0 0.0 1.9e-27 95.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KUM66004.1 - 1.2e-20 73.4 0.0 2.1e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KUM66004.1 - 3.5e-07 30.5 0.0 0.00014 22.0 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KUM66004.1 - 0.0051 17.0 0.0 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain MDMPI_N PF11716.8 KUM66004.1 - 0.012 16.2 0.4 0.028 15.1 0.4 1.6 1 1 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain GreA_GreB PF01272.19 KUM66004.1 - 0.046 13.6 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 Transcription elongation factor, GreA/GreB, C-term RTA1 PF04479.13 KUM66006.1 - 3.9e-71 238.9 12.2 4.6e-71 238.7 12.2 1.0 1 0 0 1 1 1 1 RTA1 like protein Phage_holin_3_6 PF07332.11 KUM66006.1 - 3.2 7.8 5.0 0.7 9.9 0.3 2.2 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III NAD_binding_10 PF13460.6 KUM66007.1 - 6.4e-06 26.2 0.0 8.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KUM66007.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.24 KUM66007.1 - 0.045 14.2 0.0 0.088 13.2 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KUM66007.1 - 0.066 13.1 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 KUM66007.1 - 0.094 12.2 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KUM66007.1 - 0.094 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MIP PF00230.20 KUM66008.1 - 2e-28 99.7 7.9 2.6e-28 99.3 7.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein Utp21 PF04192.12 KUM66009.1 - 8.1e-80 267.7 0.0 1.2e-79 267.1 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 KUM66009.1 - 3.5e-14 52.9 0.0 0.05 13.9 0.0 6.5 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KUM66009.1 - 1.3e-08 35.4 34.6 5.2e-05 23.9 0.4 9.7 10 1 0 10 10 10 3 WD domain, G-beta repeat Nup160 PF11715.8 KUM66009.1 - 0.035 12.8 0.0 6.9 5.2 0.0 3.1 4 0 0 4 4 4 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KUM66009.1 - 0.17 10.4 0.1 0.91 8.0 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain ABC2_membrane PF01061.24 KUM66010.1 - 2.5e-57 193.7 44.3 2.3e-34 118.7 12.3 3.8 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KUM66010.1 - 3.4e-36 124.8 0.0 2.6e-18 66.9 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KUM66010.1 - 5.9e-24 83.8 7.5 2.3e-21 75.5 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter AAA_25 PF13481.6 KUM66010.1 - 1.1e-05 25.1 0.4 0.0017 18.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KUM66010.1 - 7.6e-05 23.2 0.2 0.056 13.8 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KUM66010.1 - 0.00011 22.1 0.1 0.22 11.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KUM66010.1 - 0.00015 21.7 0.2 0.00095 19.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KUM66010.1 - 0.00026 20.2 34.7 0.0024 17.0 14.4 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 KUM66010.1 - 0.00027 20.6 0.6 0.01 15.6 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KUM66010.1 - 0.00072 20.1 0.0 0.085 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KUM66010.1 - 0.0017 18.6 0.2 0.11 12.7 0.1 3.0 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KUM66010.1 - 0.0022 17.6 0.5 0.42 10.2 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KUM66010.1 - 0.0081 15.9 0.1 1.6 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KUM66010.1 - 0.0086 16.3 0.3 0.063 13.5 0.2 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KUM66010.1 - 0.013 15.4 0.0 1 9.2 0.0 2.7 3 0 0 3 3 2 0 NACHT domain ATP-synt_ab PF00006.25 KUM66010.1 - 0.015 15.0 0.2 2.9 7.5 0.0 3.3 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 KUM66010.1 - 0.022 14.9 0.0 0.22 11.7 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 KUM66010.1 - 0.029 14.7 0.7 2.5 8.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KUM66010.1 - 0.17 11.6 0.0 5 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KUM66010.1 - 0.18 12.2 1.4 25 5.3 0.1 3.0 3 0 0 3 3 3 0 RNA helicase NB-ARC PF00931.22 KUM66010.1 - 0.2 10.8 0.1 14 4.7 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain Abhydrolase_1 PF00561.20 KUM66011.1 - 6.6e-22 78.4 0.3 4.4e-20 72.4 0.7 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KUM66011.1 - 1.2e-15 58.8 0.0 1.4e-15 58.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM66011.1 - 7e-15 54.9 0.0 8.4e-13 48.1 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KUM66011.1 - 0.00042 20.2 0.0 0.0008 19.3 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_5 PF12695.7 KUM66011.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family FBPase_glpX PF03320.13 KUM66011.1 - 0.041 12.7 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded DUF1749 PF08538.10 KUM66011.1 - 0.046 12.8 0.0 0.069 12.2 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) DUF1057 PF06342.12 KUM66011.1 - 0.048 12.7 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) LCAT PF02450.15 KUM66011.1 - 0.085 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 KUM66011.1 - 0.13 11.9 0.1 0.25 11.0 0.1 1.4 1 1 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.7 KUM66011.1 - 0.16 10.8 0.1 0.54 9.1 0.1 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme Fungal_trans PF04082.18 KUM66012.1 - 3.3e-16 59.1 0.0 4.9e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM66012.1 - 1.2e-06 28.5 11.3 2.3e-06 27.6 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAGK_cat PF00781.24 KUM66013.1 - 3.7e-11 42.7 0.0 6.2e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ribonuc_L-PSP PF01042.21 KUM66014.1 - 1.6e-19 70.1 0.0 1.9e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Gpr1_Fun34_YaaH PF01184.19 KUM66015.1 - 1.5e-35 122.7 19.4 1.8e-35 122.5 19.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family His_Phos_2 PF00328.22 KUM66016.1 - 1.8e-109 366.6 0.0 2.4e-109 366.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KUM66016.1 - 2.9e-37 126.7 0.0 6.5e-37 125.6 0.0 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KUM66016.1 - 2.2e-05 24.1 0.0 4.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Inositol_P PF00459.25 KUM66017.1 - 2.1e-65 220.9 0.0 2.6e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF676 PF05057.14 KUM66018.1 - 3.7e-42 144.3 0.0 1e-28 100.4 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) DUF915 PF06028.11 KUM66018.1 - 0.014 14.7 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 KUM66018.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) EMP70 PF02990.16 KUM66020.1 - 4.9e-200 665.6 0.1 6.5e-200 665.2 0.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF3269 PF11673.8 KUM66021.1 - 0.04 14.3 0.3 0.93 9.9 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3269) Soc PF16855.5 KUM66021.1 - 0.095 13.2 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Small outer capsid protein adh_short PF00106.25 KUM66025.1 - 5e-22 78.3 0.1 2e-20 73.1 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM66025.1 - 2.7e-16 59.8 0.1 7.5e-15 55.1 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM66025.1 - 3.1e-05 24.0 1.1 7.8e-05 22.7 1.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM66025.1 - 0.099 12.1 0.4 0.97 8.8 0.4 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3425 PF11905.8 KUM66026.1 - 4.3e-14 52.6 0.0 8.1e-14 51.7 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) CN_hydrolase PF00795.22 KUM66027.1 - 1.9e-31 109.4 0.0 5.5e-31 107.8 0.0 1.8 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Sulfatase PF00884.23 KUM66028.1 - 4.6e-60 203.6 0.2 6.7e-60 203.1 0.2 1.3 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KUM66028.1 - 1.3e-22 79.3 1.0 2.8e-22 78.3 1.0 1.6 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 KUM66028.1 - 2.8e-08 33.8 0.1 1.7e-06 27.9 0.1 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 KUM66028.1 - 0.0019 18.9 0.3 0.026 15.2 0.2 2.3 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 KUM66028.1 - 0.002 16.8 0.0 0.0026 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 KUM66028.1 - 0.0045 17.2 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF1501 PF07394.12 KUM66028.1 - 0.014 14.5 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Metalloenzyme PF01676.18 KUM66028.1 - 0.061 12.7 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Metalloenzyme superfamily NmrA PF05368.13 KUM66029.1 - 3.1e-61 206.9 0.2 3.8e-61 206.6 0.2 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM66029.1 - 1.9e-16 60.5 0.4 3.6e-16 59.6 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KUM66029.1 - 3.4e-07 29.6 0.0 4.6e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KUM66029.1 - 1.7e-05 24.4 0.1 2.6e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KUM66029.1 - 0.0046 17.2 0.1 0.0073 16.6 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KUM66029.1 - 0.035 14.4 0.1 0.056 13.7 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.24 KUM66029.1 - 0.046 14.2 0.0 0.48 10.9 0.1 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KUM66029.1 - 0.064 13.2 0.7 0.39 10.7 0.3 2.3 2 1 1 3 3 3 0 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KUM66029.1 - 0.11 12.0 0.5 0.19 11.3 0.5 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Bac_luciferase PF00296.20 KUM66030.1 - 4.3e-61 207.1 0.5 5.5e-61 206.7 0.5 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Peptidase_S64 PF08192.11 KUM66031.1 - 0.045 12.2 0.0 0.066 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 Methyltransf_2 PF00891.18 KUM66033.1 - 6.6e-15 55.0 0.0 9.3e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain NAD_binding_6 PF08030.12 KUM66035.1 - 5.6e-22 78.5 0.0 9e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KUM66035.1 - 8.8e-20 70.8 0.0 2e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KUM66035.1 - 1.4e-18 67.2 10.3 1.4e-18 67.2 10.3 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 KUM66035.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain 7TMR-DISM_7TM PF07695.11 KUM66036.1 - 0.11 12.3 3.0 0.16 11.9 2.4 1.4 1 1 0 1 1 1 0 7TM diverse intracellular signalling UDG PF03167.19 KUM66037.1 - 1.8e-18 67.0 0.1 7.1e-18 65.1 0.0 1.8 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily SBDS PF01172.18 KUM66038.1 - 8.8e-25 86.6 0.0 1.1e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Phage_TAC_5 PF08890.11 KUM66038.1 - 0.096 12.7 0.0 0.18 11.8 0.0 1.4 2 0 0 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC RhoGEF PF00621.20 KUM66039.1 - 2.5e-23 83.2 0.1 6.1e-23 82.0 0.1 1.7 1 1 0 1 1 1 1 RhoGEF domain BP28CT PF08146.12 KUM66040.1 - 1.2e-42 145.4 1.1 1.5e-41 141.9 0.6 2.6 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KUM66040.1 - 6.5e-26 91.0 5.0 8.4e-26 90.6 0.2 3.8 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 KUM66040.1 - 2e-08 34.5 0.9 0.61 10.5 0.0 6.5 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.22 KUM66040.1 - 2.1e-05 24.4 0.8 0.45 10.9 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 KUM66040.1 - 0.01 16.3 11.0 4.2 8.0 0.1 7.5 6 2 2 8 8 8 0 HEAT-like repeat CARD PF00619.21 KUM66040.1 - 0.022 14.8 2.5 0.044 13.8 0.2 2.7 3 0 0 3 3 3 0 Caspase recruitment domain ABC_tran PF00005.27 KUM66041.1 - 4.6e-45 153.5 0.0 3.8e-27 95.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 KUM66041.1 - 2e-29 103.1 25.2 1.1e-19 71.1 9.0 3.1 4 0 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KUM66041.1 - 1.2e-12 47.7 4.9 1.6e-05 24.5 1.8 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KUM66041.1 - 2.2e-08 34.3 0.1 0.13 12.0 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KUM66041.1 - 6.7e-07 29.7 0.2 0.053 13.8 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KUM66041.1 - 3.3e-06 26.7 1.9 0.0091 15.7 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KUM66041.1 - 1.4e-05 25.6 2.3 0.041 14.3 0.7 3.5 3 1 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 KUM66041.1 - 0.00011 22.7 1.7 0.076 13.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KUM66041.1 - 0.00015 21.5 0.5 0.021 14.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KUM66041.1 - 0.00054 19.1 2.1 0.34 9.9 0.2 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KUM66041.1 - 0.00057 19.8 0.3 1.2 9.1 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 KUM66041.1 - 0.00067 19.6 2.7 0.95 9.4 0.0 3.4 4 0 0 4 4 3 2 NACHT domain MMR_HSR1 PF01926.23 KUM66041.1 - 0.0018 18.3 0.4 0.96 9.5 0.0 3.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 KUM66041.1 - 0.0021 18.2 2.0 0.0084 16.2 0.4 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 KUM66041.1 - 0.0029 17.4 0.1 3.8 7.2 0.0 2.6 2 1 0 2 2 2 2 AAA domain cobW PF02492.19 KUM66041.1 - 0.003 17.2 1.1 0.11 12.1 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 KUM66041.1 - 0.0052 16.2 0.8 0.63 9.3 0.2 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.6 KUM66041.1 - 0.0092 16.1 0.6 3 8.0 0.3 3.0 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KUM66041.1 - 0.018 14.7 0.0 6.7 6.3 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KUM66041.1 - 0.021 14.1 0.3 0.93 8.7 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 KUM66041.1 - 0.027 14.2 0.0 8.1 6.1 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 KUM66041.1 - 0.03 14.3 0.1 0.52 10.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KUM66041.1 - 0.033 13.7 0.2 7.9 5.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KUM66041.1 - 0.054 14.0 0.0 12 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KUM66041.1 - 0.059 13.3 0.8 13 5.7 0.1 2.7 2 0 0 2 2 2 0 NTPase TrwB_AAD_bind PF10412.9 KUM66041.1 - 0.071 12.0 2.4 0.74 8.7 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ABC_ATPase PF09818.9 KUM66041.1 - 0.075 11.8 0.2 1.4 7.6 0.0 2.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF2075 PF09848.9 KUM66041.1 - 0.11 11.8 0.8 4.1 6.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KUM66041.1 - 0.15 11.3 0.9 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 KaiC SbcCD_C PF13558.6 KUM66041.1 - 0.18 12.1 0.2 14 6.0 0.1 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 KUM66041.1 - 0.18 12.2 0.0 11 6.5 0.0 3.0 2 0 0 2 2 2 0 RNA helicase Pox_A32 PF04665.12 KUM66041.1 - 0.19 11.1 2.2 7.2 6.0 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_5 PF07728.14 KUM66041.1 - 0.31 11.1 0.9 2.3 8.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KUM66041.1 - 0.86 9.3 3.6 21 4.8 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein Dynamin_N PF00350.23 KUM66041.1 - 2.8 8.0 8.9 3 7.9 0.1 3.0 4 0 0 4 4 2 0 Dynamin family SCP2 PF02036.17 KUM66042.1 - 3.1e-26 91.8 0.7 3.8e-26 91.5 0.7 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KUM66042.1 - 1.6e-06 28.4 0.1 2e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KUM66042.1 - 0.0055 17.1 0.0 0.0071 16.7 0.0 1.2 1 0 0 1 1 1 1 Sterol carrier protein domain Ras PF00071.22 KUM66045.1 - 4.2e-49 166.3 0.0 5.1e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM66045.1 - 2.9e-29 101.7 0.1 7.5e-29 100.4 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM66045.1 - 1.4e-10 40.9 0.0 1.8e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 KUM66045.1 - 0.00061 20.2 0.1 0.0049 17.2 0.1 2.1 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 KUM66045.1 - 0.00066 19.7 0.0 0.0015 18.6 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KUM66045.1 - 0.0015 17.9 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 KUM66045.1 - 0.015 15.1 0.1 0.02 14.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 KUM66045.1 - 0.017 14.6 0.1 0.03 13.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 KUM66045.1 - 0.019 14.2 2.0 1.7 7.8 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 KUM66045.1 - 0.029 13.9 0.1 0.046 13.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KUM66045.1 - 0.078 13.4 0.1 0.14 12.6 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain ArgoMid PF16487.5 KUM66045.1 - 0.082 13.2 0.1 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 Mid domain of argonaute RsgA_GTPase PF03193.16 KUM66045.1 - 0.096 12.6 0.1 9.5 6.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 KUM66045.1 - 0.11 12.5 0.1 0.26 11.3 0.2 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 KUM66045.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KUM66045.1 - 0.12 11.7 0.4 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_33 PF13671.6 KUM66045.1 - 0.21 11.7 0.2 0.21 11.7 0.2 1.6 2 0 0 2 2 2 0 AAA domain Nas2_N PF18265.1 KUM66046.1 - 1.2e-28 98.9 0.1 1.7e-28 98.3 0.1 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KUM66046.1 - 5.7e-12 45.3 0.3 1e-11 44.5 0.3 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KUM66046.1 - 8.4e-09 35.6 0.1 1.6e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KUM66046.1 - 3.7e-06 27.2 0.1 6.2e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KUM66046.1 - 4e-05 24.0 0.0 7e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain F-box-like PF12937.7 KUM66047.1 - 0.01 15.7 1.2 0.068 13.1 0.2 2.4 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KUM66047.1 - 0.13 12.2 1.4 0.43 10.5 0.1 2.3 2 0 0 2 2 2 0 F-box domain SNF2_N PF00176.23 KUM66048.1 - 2.9e-65 220.3 0.2 4.8e-65 219.6 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KUM66048.1 - 9.2e-16 58.2 0.0 2e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KUM66048.1 - 2e-08 33.9 3.4 4.7e-08 32.8 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KUM66048.1 - 4.9e-07 29.5 4.9 1.2e-06 28.2 4.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KUM66048.1 - 1.7e-06 28.2 0.0 4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 KUM66048.1 - 2.3e-05 24.3 2.5 4.8e-05 23.3 2.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KUM66048.1 - 0.00011 21.9 5.6 0.00022 21.0 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KUM66048.1 - 0.00018 21.8 5.1 0.00043 20.6 5.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KUM66048.1 - 0.00019 21.5 1.8 0.00044 20.3 1.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KUM66048.1 - 0.011 15.6 5.6 0.058 13.3 6.1 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 His_Phos_1 PF00300.22 KUM66048.1 - 0.027 14.2 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) zf-RING_4 PF14570.6 KUM66048.1 - 0.031 14.1 5.0 0.093 12.5 4.7 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 KUM66048.1 - 0.24 11.4 6.9 1 9.4 7.3 1.9 1 1 1 2 2 2 0 zinc-RING finger domain Aa_trans PF01490.18 KUM66049.1 - 5.1e-09 35.3 6.2 6.8e-09 34.9 6.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.6 KUM66049.1 - 0.021 14.7 2.4 0.077 12.8 0.3 2.1 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF3341 PF11821.8 KUM66049.1 - 0.24 11.0 7.1 0.044 13.4 3.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3341) DUF2407_C PF13373.6 KUM66049.1 - 1.2 9.3 2.8 8.4 6.6 0.2 2.1 1 1 1 2 2 2 0 DUF2407 C-terminal domain Aa_trans PF01490.18 KUM66050.1 - 6e-31 107.6 14.4 7.3e-31 107.3 14.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KUM66050.1 - 0.0012 18.0 14.3 0.0015 17.7 14.3 1.3 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Phage_holin_1 PF04531.13 KUM66050.1 - 1 10.0 7.6 0.3 11.6 2.4 2.8 2 1 0 2 2 2 0 Bacteriophage holin DUF373 PF04123.13 KUM66050.1 - 2.5 7.5 10.9 0.1 12.0 5.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF4199 PF13858.6 KUM66050.1 - 8.9 6.7 15.0 0.031 14.7 2.8 2.9 2 2 2 4 4 4 0 Protein of unknown function (DUF4199) PDZ_1 PF12812.7 KUM66051.1 - 4.6e-52 173.9 0.0 4e-34 116.5 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KUM66051.1 - 2e-24 87.2 1.5 3.5e-21 76.7 0.1 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 KUM66051.1 - 1.2e-15 57.1 0.5 3.2e-08 33.3 0.2 4.4 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 KUM66051.1 - 1.4e-09 38.1 0.1 0.00017 21.8 0.0 4.4 4 0 0 4 4 4 1 PDZ domain PDZ PF00595.24 KUM66051.1 - 0.00018 21.8 0.0 0.025 14.9 0.0 3.4 3 0 0 3 3 3 1 PDZ domain 4HPAD_g_N PF18671.1 KUM66051.1 - 0.0049 16.5 0.0 0.017 14.8 0.0 2.0 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Tricorn_PDZ PF14685.6 KUM66051.1 - 0.018 15.0 0.5 1.7 8.7 0.1 3.2 3 0 0 3 3 3 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 KUM66051.1 - 0.21 10.2 0.0 0.38 9.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase S46 TPR_2 PF07719.17 KUM66052.1 - 7.9e-08 31.9 3.0 0.032 14.3 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KUM66052.1 - 2e-06 27.4 3.6 0.031 14.1 0.3 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM66052.1 - 0.014 15.6 1.1 0.03 14.6 1.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KUM66052.1 - 6.2 7.3 9.5 12 6.4 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_10 PF00331.20 KUM66053.1 - 7.3e-91 304.6 0.0 8.1e-91 304.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Rox3 PF08633.10 KUM66053.1 - 0.091 13.0 0.0 0.22 11.8 0.0 1.6 2 0 0 2 2 2 0 Rox3 mediator complex subunit DUF2841 PF11001.8 KUM66054.1 - 1.9e-43 147.5 0.7 4.4e-43 146.3 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) SSXT PF05030.12 KUM66055.1 - 6.2e-08 32.2 0.0 0.012 15.2 0.0 2.4 2 0 0 2 2 2 2 SSXT protein (N-terminal region) Elf4 PF07011.11 KUM66055.1 - 0.16 11.9 0.1 26 4.8 0.0 2.7 3 0 0 3 3 3 0 Early Flowering 4 domain TFIIA PF03153.13 KUM66055.1 - 2 8.3 21.4 2.4 8.1 21.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4686 PF15742.5 KUM66056.1 - 0.0091 15.2 3.2 0.013 14.7 3.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) SKA2 PF16740.5 KUM66056.1 - 0.18 11.6 1.7 0.28 11.0 1.0 1.7 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 YabA PF06156.13 KUM66056.1 - 0.28 11.8 2.5 0.29 11.8 0.3 2.1 2 1 1 3 3 3 0 Initiation control protein YabA TEX13 PF15186.6 KUM66056.1 - 0.62 9.7 5.5 1 9.1 5.5 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family ADIP PF11559.8 KUM66056.1 - 1.7 8.7 8.0 0.38 10.8 4.5 1.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 KUM66056.1 - 7.1 7.3 6.6 25 5.6 0.5 2.7 2 1 1 3 3 3 0 SlyX Iso_dh PF00180.20 KUM66057.1 - 1.2e-107 360.1 0.0 1.4e-107 359.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pyridoxal_deC PF00282.19 KUM66058.1 - 1e-78 264.7 0.0 1.4e-78 264.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KUM66058.1 - 7.3e-05 21.9 0.0 0.0001 21.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V AMP-binding PF00501.28 KUM66059.1 - 1.3e-41 142.7 0.0 1.7e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KUM66059.1 - 1e-06 28.5 0.6 2.6e-06 27.3 0.6 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus peroxidase PF00141.23 KUM66061.1 - 1.2e-43 149.5 0.0 1.8e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF4003 PF13170.6 KUM66061.1 - 0.055 12.8 0.0 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) Peptidase_S10 PF00450.22 KUM66062.1 - 1.3e-124 416.9 0.2 1.5e-124 416.6 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KUM66062.1 - 2.9e-14 53.7 0.2 7.8e-14 52.3 0.2 1.8 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide Sec34 PF04136.15 KUM66062.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Sec34-like family Ribosomal_S13 PF00416.22 KUM66063.1 - 3.5e-56 189.1 3.0 4.2e-56 188.8 3.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF1822 PF08852.11 KUM66063.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) FbpA PF05833.11 KUM66063.1 - 0.026 13.3 0.0 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 KUM66063.1 - 0.058 13.7 0.0 0.15 12.3 0.0 1.7 1 1 0 1 1 1 0 Helix-hairpin-helix motif DUF2746 PF10874.8 KUM66063.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) PALP PF00291.25 KUM66064.1 - 2.6e-39 135.4 1.4 3.8e-39 134.9 1.4 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Mucin PF01456.17 KUM66064.1 - 0.6 10.1 17.9 0.46 10.5 16.2 1.7 1 1 0 1 1 1 0 Mucin-like glycoprotein SBDS_C PF09377.10 KUM66065.1 - 1.5e-42 144.3 0.0 2.4e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KUM66065.1 - 2.1e-31 107.8 0.0 4.5e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein AP3D1 PF06375.11 KUM66065.1 - 0.044 14.0 2.7 0.067 13.4 1.9 1.6 1 1 0 1 1 1 0 AP-3 complex subunit delta-1 DUF5435 PF17503.2 KUM66067.1 - 1.1 8.9 3.6 0.43 10.3 0.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5435) Bac_luciferase PF00296.20 KUM66068.1 - 6.9e-57 193.2 2.4 8.8e-57 192.9 2.4 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SSF PF00474.17 KUM66069.1 - 1.1e-20 74.0 30.5 1.1e-20 74.0 30.5 1.7 3 0 0 3 3 3 1 Sodium:solute symporter family Glyco_hydro_18 PF00704.28 KUM66070.1 - 6e-86 289.0 5.6 6.9e-86 288.8 5.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 EthD PF07110.11 KUM66071.1 - 8.4e-18 65.3 0.5 9.8e-18 65.1 0.5 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KUM66071.1 - 0.0022 18.5 0.0 0.0042 17.5 0.0 1.4 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Arrestin_N PF00339.29 KUM66072.1 - 8.5e-07 29.1 0.0 2.9e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_N PF04425.12 KUM66072.1 - 3.3e-05 22.8 2.3 0.00057 18.8 0.2 2.4 1 1 1 2 2 2 2 Bul1 N terminus Bul1_C PF04426.12 KUM66072.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Bul1 C terminus MMS1_N PF10433.9 KUM66073.1 - 4.4e-154 513.8 0.0 5.9e-154 513.3 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KUM66073.1 - 9e-100 334.1 0.0 5.4e-99 331.6 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 KUM66073.1 - 0.026 14.8 0.0 0.28 11.5 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ubiquitin PF00240.23 KUM66074.1 - 6.8e-20 70.6 0.1 1e-19 70.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KUM66074.1 - 1.5e-07 31.2 0.0 2.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 KUM66074.1 - 2.1e-07 30.7 0.2 2.1e-07 30.7 0.2 2.1 2 0 0 2 2 2 1 UBA/TS-N domain DUF2407 PF10302.9 KUM66074.1 - 3.2e-05 24.4 0.1 6.3e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KUM66074.1 - 0.00012 22.1 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 KUM66074.1 - 0.0003 21.4 0.0 0.00069 20.3 0.0 1.6 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD GerD PF17898.1 KUM66074.1 - 0.077 13.0 4.2 0.18 11.7 4.1 1.7 1 1 0 1 1 1 0 Spore germination GerD central core domain Ubiquitin_2 PF14560.6 KUM66074.1 - 0.12 12.8 0.1 0.35 11.3 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain HOIP-UBA PF16678.5 KUM66074.1 - 0.24 11.4 0.0 0.46 10.5 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair STI1 PF17830.1 KUM66074.1 - 1.5 8.8 21.7 1.3 9.0 2.7 3.6 2 1 1 3 3 3 0 STI1 domain DUF2477 PF10631.9 KUM66074.1 - 3.1 8.5 12.3 0.063 13.9 1.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2477) XPC-binding PF09280.11 KUM66074.1 - 7.1 6.4 13.4 20 5.0 5.6 3.6 2 1 1 3 3 3 0 XPC-binding domain RTA1 PF04479.13 KUM66075.1 - 3.2e-69 232.7 10.0 3.2e-69 232.7 10.0 1.5 2 0 0 2 2 2 1 RTA1 like protein B12D PF06522.11 KUM66075.1 - 0.17 11.7 0.0 0.47 10.3 0.0 1.7 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit NRDE-2 PF08424.10 KUM66076.1 - 6e-87 291.8 0.9 1.6e-86 290.4 0.1 1.9 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference Bombesin PF02044.17 KUM66076.1 - 1.4 9.2 5.3 22 5.4 0.3 3.2 3 0 0 3 3 3 0 Bombesin-like peptide zf-CCHC_3 PF13917.6 KUM66077.1 - 1e-11 44.6 1.0 1e-07 31.8 0.1 2.6 2 0 0 2 2 2 2 Zinc knuckle SUZ PF12752.7 KUM66078.1 - 1.3e-15 57.9 4.5 1.3e-15 57.9 4.5 4.2 2 1 0 2 2 2 1 SUZ domain R3H PF01424.22 KUM66078.1 - 1.9e-06 27.7 0.0 4.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 R3H domain DUF1242 PF06842.12 KUM66079.1 - 3.2e-17 62.0 0.1 4.9e-17 61.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) TFIID-18kDa PF02269.16 KUM66080.1 - 1.2e-23 82.9 0.0 2.1e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.6 KUM66080.1 - 0.00096 19.5 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KUM66080.1 - 0.0039 17.5 0.0 0.0039 17.5 0.0 3.4 4 1 0 4 4 4 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 KUM66080.1 - 0.0052 17.3 0.0 0.0092 16.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Bromo_TP PF07524.13 KUM66080.1 - 0.0062 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 KUM66080.1 - 0.014 15.5 0.2 0.033 14.3 0.2 1.6 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KUM66080.1 - 0.028 14.6 0.1 0.052 13.7 0.1 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KUM66080.1 - 0.049 13.9 0.1 0.049 13.9 0.1 2.5 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Herpes_BLLF1 PF05109.13 KUM66080.1 - 0.26 9.2 30.4 0.46 8.4 30.4 1.3 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) PPR_2 PF13041.6 KUM66082.1 - 3.4e-12 46.4 5.0 1e-05 25.7 0.1 4.8 5 1 1 6 6 6 3 PPR repeat family PPR_3 PF13812.6 KUM66082.1 - 2.7e-08 33.7 0.3 0.0046 17.0 0.0 3.9 2 2 1 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 KUM66082.1 - 6.5e-07 29.2 0.2 0.027 14.7 0.0 3.9 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.7 KUM66082.1 - 2.8e-05 23.7 0.0 0.0059 16.3 0.0 3.1 3 0 0 3 3 3 2 PPR repeat Rhomboid PF01694.22 KUM66084.1 - 1.4e-20 73.9 11.1 2e-20 73.3 10.0 1.7 2 0 0 2 2 2 1 Rhomboid family Shugoshin_N PF07558.11 KUM66085.1 - 0.0039 17.0 0.2 0.11 12.3 0.0 2.2 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region UPF0242 PF06785.11 KUM66085.1 - 0.03 14.4 0.4 0.037 14.1 0.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NAD_binding_6 PF08030.12 KUM66085.1 - 0.089 12.9 0.0 0.097 12.8 0.0 1.1 1 0 0 1 1 1 0 Ferric reductase NAD binding domain ZapB PF06005.12 KUM66085.1 - 0.27 11.7 4.1 0.45 11.0 1.2 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Mob1_phocein PF03637.17 KUM66086.1 - 1.4e-50 171.6 0.0 6e-50 169.6 0.0 1.9 1 1 0 1 1 1 1 Mob1/phocein family NdhO PF11910.8 KUM66086.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Cyanobacterial and plant NDH-1 subunit O AA_permease_2 PF13520.6 KUM66087.1 - 3.7e-41 141.3 49.2 4.6e-41 141.0 49.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM66087.1 - 6.5e-25 87.7 43.8 8.6e-25 87.3 43.8 1.0 1 0 0 1 1 1 1 Amino acid permease PhoD PF09423.10 KUM66088.1 - 8.1e-10 38.2 2.5 7.9e-05 21.8 0.4 3.0 2 1 0 2 2 2 2 PhoD-like phosphatase Ammonium_transp PF00909.21 KUM66089.1 - 0.049 12.3 6.9 0.072 11.8 6.9 1.1 1 0 0 1 1 1 0 Ammonium Transporter Family MraZ PF02381.18 KUM66090.1 - 0.097 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like Leo1 PF04004.13 KUM66091.1 - 7.4e-26 91.0 1.7 1.5e-25 89.9 0.0 2.3 2 1 0 2 2 2 1 Leo1-like protein CTP_transf_like PF01467.26 KUM66093.1 - 1.2e-29 103.3 0.0 2e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1 PF05636.11 KUM66093.1 - 0.2 10.8 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase YhhN PF07947.14 KUM66094.1 - 6.2e-47 159.6 11.2 7.2e-47 159.4 11.2 1.1 1 0 0 1 1 1 1 YhhN family PP2C PF00481.21 KUM66095.1 - 1.1e-80 271.0 0.0 1.4e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C UTP25 PF06862.12 KUM66098.1 - 1.6e-190 633.9 0.0 1.9e-190 633.7 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KUM66098.1 - 0.00019 21.2 0.1 0.009 15.8 0.1 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase FoP_duplication PF13865.6 KUM66098.1 - 0.64 10.6 12.0 1.5 9.4 12.0 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 EamA PF00892.20 KUM66100.1 - 2.1e-19 70.1 33.2 1.6e-13 51.0 10.3 2.5 2 1 0 2 2 2 2 EamA-like transporter family Ank_2 PF12796.7 KUM66101.1 - 8.5e-48 160.9 0.0 1.5e-13 51.1 0.0 4.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM66101.1 - 3.1e-26 91.4 1.0 4.4e-06 27.1 0.0 5.1 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM66101.1 - 9.6e-24 80.9 6.0 0.0036 17.7 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KUM66101.1 - 2.3e-21 75.6 6.6 1.6e-05 25.0 0.0 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KUM66101.1 - 1.1e-19 69.9 16.8 0.0037 17.6 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat NACHT PF05729.12 KUM66101.1 - 1.3e-05 25.2 0.1 3.3e-05 23.9 0.1 1.8 1 1 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 KUM66101.1 - 0.00038 19.8 0.2 0.019 14.3 0.0 2.6 2 1 0 2 2 2 1 Phosphorylase superfamily AAA_16 PF13191.6 KUM66101.1 - 0.012 16.0 0.0 0.065 13.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KUM66101.1 - 0.024 14.9 0.2 0.15 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Jnk-SapK_ap_N PF09744.9 KUM66101.1 - 0.12 12.5 1.5 0.52 10.5 0.0 2.5 3 1 0 3 3 3 0 JNK_SAPK-associated protein-1 KAP_NTPase PF07693.14 KUM66101.1 - 0.18 11.0 0.5 0.55 9.4 0.3 1.7 1 1 0 2 2 2 0 KAP family P-loop domain MFS_1 PF07690.16 KUM66102.1 - 8.7e-34 117.0 45.7 2.7e-32 112.1 43.5 3.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM66102.1 - 6.5e-14 51.3 23.4 2.1e-13 49.6 23.4 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.25 KUM66103.1 - 3.5e-23 82.1 0.0 1.3e-17 63.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM66103.1 - 1.3e-10 41.3 0.0 3.9e-07 29.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM66103.1 - 4.4e-05 23.5 0.0 6.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 KUM66104.1 - 0.00012 21.2 4.4 0.00013 21.1 4.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Bax1-I PF01027.20 KUM66104.1 - 0.093 12.5 6.7 0.2 11.5 6.7 1.5 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Ribosom_S12_S23 PF00164.25 KUM66105.1 - 1.6e-50 169.5 0.8 2e-50 169.2 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 IF-2B PF01008.17 KUM66106.1 - 3.2e-63 213.6 0.5 1.2e-37 129.7 0.0 2.3 2 1 0 2 2 2 2 Initiation factor 2 subunit family TALPID3 PF15324.6 KUM66106.1 - 0.14 9.8 1.0 0.2 9.3 1.0 1.1 1 0 0 1 1 1 0 Hedgehog signalling target NIF PF03031.18 KUM66107.1 - 3.2e-59 199.2 0.0 5.4e-59 198.4 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Glyco_hydro_76 PF03663.14 KUM66108.1 - 2.7e-147 491.1 22.7 3.4e-147 490.8 22.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DAO PF01266.24 KUM66109.1 - 1.8e-30 106.7 0.0 2e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KUM66109.1 - 0.00083 19.9 1.9 0.0052 17.3 0.9 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM66109.1 - 0.0042 16.2 0.0 0.0058 15.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KUM66109.1 - 0.01 15.1 0.1 0.019 14.2 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KUM66109.1 - 0.013 15.9 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KUM66109.1 - 0.024 14.9 0.2 0.057 13.7 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KUM66109.1 - 0.037 13.3 0.3 0.07 12.4 0.3 1.4 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 KUM66109.1 - 0.047 13.3 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KUM66109.1 - 0.05 13.9 0.7 0.11 12.8 0.7 1.6 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 KUM66109.1 - 0.13 11.5 0.5 0.22 10.8 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain DUF1188 PF06690.11 KUM66109.1 - 0.24 10.9 0.3 0.36 10.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) MFS_1 PF07690.16 KUM66110.1 - 1e-30 106.9 32.0 1e-30 106.9 32.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily His_Phos_1 PF00300.22 KUM66111.1 - 0.00012 21.9 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) N2227 PF07942.12 KUM66113.1 - 4.7e-59 199.8 0.0 5.7e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KUM66113.1 - 2.4e-05 24.2 0.0 4.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM66113.1 - 0.00012 22.7 0.0 0.00088 19.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM66113.1 - 0.00049 20.8 0.0 0.0017 19.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM66113.1 - 0.0028 18.3 0.0 0.027 15.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM66113.1 - 0.05 13.4 0.0 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KUM66113.1 - 0.19 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MFS_1 PF07690.16 KUM66114.1 - 3.5e-21 75.5 52.0 5.4e-13 48.6 24.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_E8 PF03394.13 KUM66114.1 - 0.0095 15.5 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 Poxvirus E8 protein Polyketide_cyc2 PF10604.9 KUM66115.1 - 0.13 12.6 3.9 0.75 10.1 3.9 2.1 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport FAD_binding_3 PF01494.19 KUM66116.1 - 6.1e-51 173.7 0.0 9.3e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Fungal_trans PF04082.18 KUM66117.1 - 5.7e-13 48.5 0.6 1e-12 47.6 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM66117.1 - 1.3e-06 28.5 13.3 2.5e-06 27.5 13.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEPN_DZIP3 PF18738.1 KUM66117.1 - 0.062 13.0 0.2 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 DZIP3/ hRUL138-like HEPN Trimer_CC PF08954.11 KUM66117.1 - 0.18 11.4 1.2 0.53 9.9 1.2 1.8 1 0 0 1 1 1 0 Trimerisation motif DUF3328 PF11807.8 KUM66119.1 - 0.0038 17.0 1.2 0.0052 16.6 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) EFG_IV PF03764.18 KUM66120.1 - 1.2e-06 28.3 1.3 19 5.1 0.0 4.9 1 1 4 5 5 5 5 Elongation factor G, domain IV SHNi-TPR PF10516.9 KUM66120.1 - 0.017 14.6 0.4 1.3e+02 2.2 0.0 4.6 5 0 0 5 5 5 0 SHNi-TPR Imm75 PF15660.6 KUM66120.1 - 0.052 13.8 0.5 7.7 6.9 0.1 2.4 1 1 3 4 4 4 0 Putative Immunity protein 75 DUF3254 PF11630.8 KUM66120.1 - 0.068 13.4 0.1 26 5.1 0.0 2.5 1 1 3 4 4 4 0 Protein of unknown function (DUF3254) MOZART1 PF12554.8 KUM66121.1 - 2.6e-24 84.7 1.7 3.1e-24 84.5 1.7 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DUF1844 PF08899.11 KUM66121.1 - 0.0033 17.7 0.4 0.0047 17.2 0.2 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1844) WXG100 PF06013.12 KUM66121.1 - 0.042 14.1 0.1 0.85 9.9 0.1 2.0 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DHHA1 PF02272.19 KUM66121.1 - 0.075 13.5 0.1 0.087 13.2 0.1 1.1 1 0 0 1 1 1 0 DHHA1 domain CUE PF02845.16 KUM66122.1 - 3.7e-12 45.7 0.0 5.7e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 KUM66122.1 - 0.018 14.9 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain AFOR_C PF01314.18 KUM66122.1 - 0.026 13.5 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 HA2 PF04408.23 KUM66123.1 - 5.9e-16 58.7 0.1 1.1e-15 57.8 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KUM66123.1 - 9e-13 48.4 0.0 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KUM66123.1 - 2.9e-12 46.9 0.0 6.6e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KUM66123.1 - 2.7e-06 27.7 0.0 6.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KUM66123.1 - 7.3e-06 25.9 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KUM66123.1 - 0.00013 21.7 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KUM66123.1 - 0.00014 22.2 0.2 0.0012 19.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 KUM66123.1 - 0.0024 17.5 0.1 0.046 13.3 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 KUM66123.1 - 0.029 13.5 0.0 0.066 12.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Herpes_ori_bp PF02399.15 KUM66123.1 - 0.049 11.7 0.0 0.068 11.2 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein DUF2075 PF09848.9 KUM66123.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KUM66123.1 - 0.12 12.4 0.1 7 6.7 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KUM66123.1 - 0.14 12.3 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain FBPase_2 PF06874.11 KUM66123.1 - 0.15 10.3 0.0 0.24 9.6 0.0 1.2 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase AAA_23 PF13476.6 KUM66123.1 - 0.21 12.1 0.0 0.42 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KUM66124.1 - 2e-89 296.8 0.0 1e-43 148.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KUM66124.1 - 1.2e-22 79.4 1.1 6.4e-10 38.7 0.1 2.9 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KUM66124.1 - 9.8e-14 52.1 0.9 0.00013 22.4 0.1 4.6 2 2 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 KUM66124.1 - 1.1e-13 51.3 0.0 2.6e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KUM66124.1 - 4.4e-12 46.4 0.5 0.015 15.6 0.0 5.2 3 2 3 6 6 5 2 AAA domain AAA_2 PF07724.14 KUM66124.1 - 1.8e-10 41.2 0.0 0.00022 21.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KUM66124.1 - 1.8e-10 41.0 0.2 0.0014 18.6 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KUM66124.1 - 3.9e-10 40.0 0.0 0.00013 22.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.13 KUM66124.1 - 9.8e-09 34.9 0.1 0.00013 21.3 0.0 2.5 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 KUM66124.1 - 5.7e-08 32.9 0.0 0.0023 18.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KUM66124.1 - 1.2e-07 32.1 0.0 0.0077 16.6 0.0 2.7 2 1 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 KUM66124.1 - 1.1e-06 29.3 0.0 0.026 15.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KUM66124.1 - 1.1e-06 28.5 0.1 0.045 13.5 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KUM66124.1 - 1.7e-06 27.6 0.3 0.045 13.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KUM66124.1 - 2.2e-06 27.6 0.0 0.0078 16.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KUM66124.1 - 2.7e-06 27.7 0.0 0.03 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KUM66124.1 - 4.5e-06 26.1 0.0 0.06 12.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin ATPase PF06745.13 KUM66124.1 - 1.1e-05 25.0 0.1 0.37 10.1 0.0 3.4 2 1 0 3 3 3 2 KaiC Rad17 PF03215.15 KUM66124.1 - 1.7e-05 24.8 0.0 0.087 12.7 0.0 2.6 2 1 0 2 2 2 2 Rad17 P-loop domain AAA_7 PF12775.7 KUM66124.1 - 1.9e-05 24.2 0.0 0.072 12.6 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 KUM66124.1 - 2.9e-05 23.7 0.4 2.6 7.6 0.0 3.7 2 1 1 3 3 3 2 AAA domain TsaE PF02367.17 KUM66124.1 - 3e-05 24.0 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin2 PF13189.6 KUM66124.1 - 5.1e-05 23.5 0.0 0.0082 16.3 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family NACHT PF05729.12 KUM66124.1 - 5.3e-05 23.2 0.2 1 9.3 0.0 3.6 3 1 1 4 4 3 2 NACHT domain AAA_17 PF13207.6 KUM66124.1 - 5.6e-05 23.6 0.2 0.18 12.2 0.2 3.3 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KUM66124.1 - 8.1e-05 23.1 0.0 0.35 11.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.26 KUM66124.1 - 0.00013 21.7 0.0 0.3 10.8 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain PhoH PF02562.16 KUM66124.1 - 0.00016 21.2 0.0 0.24 10.8 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.22 KUM66124.1 - 0.00057 19.1 0.0 0.99 8.5 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain Sigma54_activ_2 PF14532.6 KUM66124.1 - 0.00083 19.5 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain SKI PF01202.22 KUM66124.1 - 0.001 19.2 0.0 1.1 9.4 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase AAA_11 PF13086.6 KUM66124.1 - 0.0011 18.8 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KUM66124.1 - 0.0015 18.3 0.0 0.98 9.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain TniB PF05621.11 KUM66124.1 - 0.0019 17.6 0.0 1.9 7.9 0.0 3.3 3 0 0 3 3 3 1 Bacterial TniB protein AFG1_ATPase PF03969.16 KUM66124.1 - 0.0023 16.9 0.3 0.53 9.1 0.0 2.8 3 1 0 3 3 3 1 AFG1-like ATPase Parvo_NS1 PF01057.17 KUM66124.1 - 0.0024 17.0 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 KUM66124.1 - 0.0028 17.6 0.0 1.9 8.4 0.0 3.4 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KUM66124.1 - 0.0066 16.2 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 KUM66124.1 - 0.0077 15.4 0.0 0.085 12.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KUM66124.1 - 0.015 15.7 1.2 7.9 6.8 0.1 3.2 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KUM66124.1 - 0.02 14.1 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SRPRB PF09439.10 KUM66124.1 - 0.034 13.6 0.0 29 4.0 0.0 3.3 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit CPT PF07931.12 KUM66124.1 - 0.045 13.6 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein IPT PF01745.16 KUM66124.1 - 0.052 12.9 0.0 5.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase NTPase_1 PF03266.15 KUM66124.1 - 0.058 13.3 0.0 6.7 6.6 0.0 2.8 2 1 1 3 3 3 0 NTPase ResIII PF04851.15 KUM66124.1 - 0.064 13.3 0.0 18 5.3 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit BET PF17035.5 KUM66124.1 - 0.15 12.3 1.1 1.9 8.7 0.2 2.6 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation AAA_30 PF13604.6 KUM66124.1 - 0.15 11.7 0.1 29 4.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain BOP1NT PF08145.12 KUM66125.1 - 3.1e-107 358.3 7.4 4.6e-107 357.8 7.4 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KUM66125.1 - 1.1e-23 83.0 5.3 1.4e-09 38.4 0.2 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM66125.1 - 1.4e-06 28.5 0.0 0.0067 16.7 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain He_PIG PF05345.12 KUM66126.1 - 4.6e-15 55.5 4.7 0.00048 20.3 0.2 4.6 4 0 0 4 4 4 3 Putative Ig domain SKG6 PF08693.10 KUM66126.1 - 8.6e-06 25.1 0.3 1.7e-05 24.1 0.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KUM66126.1 - 0.034 13.9 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Acetyltransf_1 PF00583.25 KUM66127.1 - 2.7e-11 43.7 0.0 3.4e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KUM66127.1 - 5.1e-09 36.0 0.0 8.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KUM66127.1 - 1.6e-07 31.7 0.1 2.1e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KUM66127.1 - 3e-07 30.4 0.0 3.5e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KUM66127.1 - 5e-05 23.5 0.0 6.9e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KUM66127.1 - 0.002 17.8 0.2 0.0026 17.5 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 KUM66127.1 - 0.0021 18.1 0.1 0.0041 17.2 0.1 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KUM66127.1 - 0.0022 18.2 0.0 0.0022 18.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DpnI_C PF17726.1 KUM66127.1 - 0.042 14.0 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 Dam-replacing HTH domain AIM5 PF17050.5 KUM66128.1 - 2.6e-13 50.6 3.4 3.6e-13 50.1 3.4 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 DUF2247 PF10004.9 KUM66128.1 - 0.045 13.5 0.1 0.054 13.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) Ribosomal_L17 PF01196.19 KUM66129.1 - 7.6e-30 103.7 0.5 4.8e-29 101.1 0.0 2.3 3 0 0 3 3 3 1 Ribosomal protein L17 Mg_chelatase_C PF13335.6 KUM66129.1 - 0.63 10.7 5.0 0.23 12.1 1.0 2.1 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal cwf18 PF08315.12 KUM66130.1 - 1.6e-42 145.3 7.3 1.6e-42 145.3 7.3 1.4 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor HK97-gp10_like PF04883.12 KUM66130.1 - 1.7 9.7 5.0 0.98 10.4 1.0 2.2 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Ank_2 PF12796.7 KUM66132.1 - 3.9e-59 197.2 5.2 4.7e-16 59.2 0.1 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM66132.1 - 3.2e-33 113.7 6.2 1.5e-11 44.6 0.0 5.7 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KUM66132.1 - 3.9e-27 93.5 10.6 0.00047 20.5 0.1 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 KUM66132.1 - 4.2e-26 88.1 2.5 0.00011 22.4 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KUM66132.1 - 4e-20 71.6 7.8 2e-06 27.9 0.1 5.6 1 1 5 6 6 6 5 Ankyrin repeats (many copies) ABM PF03992.16 KUM66134.1 - 0.083 13.0 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Metallophos PF00149.28 KUM66135.1 - 6.5e-07 30.0 3.0 9.4e-07 29.5 3.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PITH PF06201.13 KUM66136.1 - 2e-41 141.8 0.0 2.3e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain Snf7 PF03357.21 KUM66137.1 - 3.1e-35 121.3 3.1 3.7e-35 121.1 3.1 1.1 1 0 0 1 1 1 1 Snf7 MR_MLE_N PF02746.16 KUM66137.1 - 0.031 14.5 0.1 0.13 12.5 0.1 1.9 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain RRM_1 PF00076.22 KUM66138.1 - 2.6e-15 56.0 0.0 4.2e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KUM66138.1 - 0.015 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Spc7 PF08317.11 KUM66138.1 - 0.021 13.7 3.9 0.026 13.4 3.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 KUM66138.1 - 0.023 14.0 2.7 0.033 13.5 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) COG6 PF06419.11 KUM66138.1 - 0.027 12.7 0.4 0.033 12.4 0.4 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 BLOC1_2 PF10046.9 KUM66138.1 - 0.031 14.6 2.0 0.05 13.9 2.0 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 KUM66138.1 - 0.055 13.9 0.5 0.1 13.1 0.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 KUM66138.1 - 0.1 12.4 2.8 0.13 12.0 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Troponin PF00992.20 KUM66138.1 - 0.2 12.0 5.6 0.3 11.4 5.6 1.2 1 0 0 1 1 1 0 Troponin V_ATPase_I PF01496.19 KUM66138.1 - 0.34 8.8 0.4 0.39 8.6 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ZapB PF06005.12 KUM66138.1 - 0.47 10.9 6.5 0.84 10.1 6.5 1.3 1 0 0 1 1 1 0 Cell division protein ZapB TRAP_alpha PF03896.16 KUM66138.1 - 0.65 9.2 2.7 0.84 8.8 2.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DivIC PF04977.15 KUM66138.1 - 0.94 9.3 4.6 1.4 8.7 4.6 1.3 1 0 0 1 1 1 0 Septum formation initiator APG6_N PF17675.1 KUM66138.1 - 1.2 9.7 8.8 1.6 9.2 8.8 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region HECT PF00632.25 KUM66139.1 - 7.4e-96 321.2 0.0 9.5e-96 320.9 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KUM66139.1 - 2.6e-32 110.6 20.5 1.2e-12 47.7 3.1 4.1 4 0 0 4 4 4 3 WW domain Rrn6 PF10214.9 KUM66139.1 - 0.54 8.7 7.8 0.83 8.1 7.8 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Strep_his_triad PF04270.13 KUM66140.1 - 3.1 7.9 8.4 51 4.0 0.2 3.2 3 0 0 3 3 3 0 Streptococcal histidine triad protein JAB PF01398.21 KUM66141.1 - 1.1e-19 70.5 0.0 2.4e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KUM66141.1 - 2.3e-19 69.9 0.8 3.8e-19 69.2 0.8 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 KUM66141.1 - 0.00081 19.5 0.0 0.0032 17.6 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) DUF5315 PF17242.2 KUM66142.1 - 1.2e-25 89.1 1.5 3.1e-25 87.8 0.6 2.1 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) DUF3870 PF12986.7 KUM66143.1 - 0.0098 16.1 0.3 4 7.7 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3870) HARE-HTH PF05066.13 KUM66143.1 - 0.19 12.2 0.0 0.48 10.9 0.0 1.7 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain Isochorismatase PF00857.20 KUM66144.1 - 2.1e-36 125.7 0.2 2.4e-36 125.5 0.2 1.0 1 0 0 1 1 1 1 Isochorismatase family Mic1 PF07035.12 KUM66144.1 - 0.052 13.3 0.1 0.085 12.6 0.1 1.4 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like MFS_1 PF07690.16 KUM66145.1 - 2.5e-42 145.1 62.5 3.3e-42 144.7 60.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM66145.1 - 1e-13 50.6 31.0 3.8e-13 48.7 31.0 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM66145.1 - 7.8e-12 44.8 11.7 7.8e-12 44.8 11.7 3.5 4 0 0 4 4 4 2 Sugar (and other) transporter Zn_clus PF00172.18 KUM66146.1 - 5.4e-08 32.8 8.0 9.6e-08 32.0 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM66146.1 - 4.5e-05 22.4 0.1 7.6e-05 21.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TIG_plexin PF17960.1 KUM66147.1 - 0.022 14.7 0.2 3 7.9 0.0 2.6 2 1 0 2 2 2 0 TIG domain MF_alpha_N PF05436.11 KUM66147.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Lamp PF01299.17 KUM66147.1 - 0.17 11.7 2.0 13 5.7 0.2 2.4 2 1 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Cu_amine_oxid PF01179.20 KUM66148.1 - 1.5e-162 541.2 0.7 1.8e-162 540.9 0.7 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KUM66148.1 - 1.3e-05 25.5 0.0 3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KUM66148.1 - 1.4e-05 25.2 0.1 3e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF5026 PF16429.5 KUM66148.1 - 0.022 14.8 0.0 0.072 13.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5026) Peptidase_M7 PF02031.16 KUM66149.1 - 0.2 11.8 3.8 0.14 12.3 1.5 1.9 1 1 1 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Abhydrolase_4 PF08386.10 KUM66151.1 - 6.5e-26 90.4 0.0 1.4e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KUM66151.1 - 6.1e-18 65.4 0.1 6.7e-14 52.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Aldolase_II PF00596.21 KUM66152.1 - 3e-48 164.2 0.1 4.4e-48 163.7 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ATP-synt_Eps PF04627.13 KUM66153.1 - 1.1e-23 83.0 1.4 1.8e-23 82.2 1.4 1.4 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain RE_HaeIII PF09556.10 KUM66153.1 - 0.091 11.8 0.0 0.092 11.8 0.0 1.0 1 0 0 1 1 1 0 HaeIII restriction endonuclease FUSC PF04632.12 KUM66154.1 - 5.5 5.4 4.9 8.3 4.8 4.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DDE_1 PF03184.19 KUM66155.1 - 1.1e-10 41.4 0.1 1.8e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease bZIP_2 PF07716.15 KUM66155.1 - 0.14 12.3 1.2 0.35 11.0 1.2 1.6 1 0 0 1 1 1 0 Basic region leucine zipper NAM-associated PF14303.6 KUM66155.1 - 1.2 9.8 6.4 59 4.3 7.2 2.6 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Acetyltransf_7 PF13508.7 KUM66156.1 - 3.4e-06 27.4 0.1 6.4e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KUM66156.1 - 1.2e-05 25.2 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM66156.1 - 4e-05 23.8 0.1 6.1e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KUM66156.1 - 0.0003 20.8 0.1 0.00051 20.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KUM66156.1 - 0.003 17.5 0.0 0.0064 16.4 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 KUM66156.1 - 0.014 15.0 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Cellulase PF00150.18 KUM66157.1 - 3.1e-17 62.9 7.8 4.1e-17 62.5 7.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF624 PF04854.14 KUM66157.1 - 0.077 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF624 NAAA-beta PF15508.6 KUM66158.1 - 0.0078 16.5 3.7 25 5.3 0.0 7.0 8 1 1 9 9 9 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Het-C PF07217.11 KUM66158.1 - 0.044 12.3 1.3 3.5 6.0 0.1 2.5 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C BUD22 PF09073.10 KUM66158.1 - 0.15 11.4 6.3 0.026 13.9 2.4 1.6 2 0 0 2 2 2 0 BUD22 Ribosomal_L27_C PF18471.1 KUM66158.1 - 0.22 10.9 3.1 1.9e+02 1.3 0.0 5.6 6 1 2 8 8 8 0 Ribosomal L27 protein C-terminal domain DUF3206 PF11472.8 KUM66158.1 - 2 8.4 8.3 4.1 7.4 0.3 4.2 3 1 2 5 5 5 0 Protein of unknown function (DUF3206) DUF5427 PF10310.9 KUM66158.1 - 2.6 6.9 9.2 0.65 8.9 5.5 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5427) V-SNARE PF05008.15 KUM66158.1 - 3.9 7.9 5.6 30 5.1 0.0 5.1 6 1 2 8 8 8 0 Vesicle transport v-SNARE protein N-terminus CLASP_N PF12348.8 KUM66158.1 - 5.7 6.4 6.7 22 4.5 0.6 3.5 2 1 2 4 4 4 0 CLASP N terminal Fungal_trans PF04082.18 KUM66159.1 - 0.0013 17.8 1.6 0.0016 17.5 0.1 1.9 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM66160.1 - 9.2e-09 35.3 11.1 1.7e-08 34.5 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Troponin-I_N PF11636.8 KUM66160.1 - 0.19 11.7 3.6 0.27 11.2 0.0 2.7 2 0 0 2 2 2 0 Troponin I residues 1-32 Mak10 PF04112.13 KUM66161.1 - 2.7e-64 215.7 0.0 4.3e-64 215.1 0.0 1.3 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase HA2 PF04408.23 KUM66163.1 - 2.3e-21 76.1 0.2 2.3e-21 76.1 0.2 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KUM66163.1 - 3.9e-14 52.8 0.0 8.8e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KUM66163.1 - 2e-12 47.4 0.0 6.7e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KUM66163.1 - 4.2e-05 23.4 0.0 8.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KUM66163.1 - 0.0014 18.9 0.0 0.0057 16.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KUM66163.1 - 0.011 15.3 0.0 0.034 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KUM66163.1 - 0.014 15.2 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 KUM66163.1 - 0.027 14.8 0.0 0.13 12.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KUM66163.1 - 0.028 14.1 0.0 0.11 12.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KUM66163.1 - 0.034 13.7 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 KUM66163.1 - 0.051 12.6 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 KUM66163.1 - 0.059 12.7 0.0 0.46 9.8 0.0 2.1 2 0 0 2 2 2 0 KaiC TMEM214 PF10151.9 KUM66163.1 - 7.9 4.8 5.8 12 4.2 5.8 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Elf4 PF07011.11 KUM66164.1 - 0.048 13.6 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Early Flowering 4 domain zf-MYND PF01753.18 KUM66165.1 - 2.9e-09 36.9 16.6 6.7e-09 35.7 16.6 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KUM66165.1 - 4.3 7.7 10.1 9.8 6.6 10.1 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding HSP20 PF00011.21 KUM66166.1 - 2.8e-13 49.9 0.2 3.8e-13 49.4 0.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KUM66166.1 - 6.8e-05 22.4 0.2 0.00027 20.4 0.1 2.0 1 1 1 2 2 2 1 HSP20-like domain found in ArsA CS PF04969.16 KUM66166.1 - 0.036 15.1 0.0 0.075 14.1 0.0 1.5 1 0 0 1 1 1 0 CS domain FKBP26_C PF18046.1 KUM66166.1 - 0.11 12.6 0.2 2.6 8.2 0.1 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal Arylsulfotran_2 PF14269.6 KUM66167.1 - 2.3e-57 194.6 1.4 3.1e-57 194.2 1.4 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KUM66167.1 - 1.7e-13 50.3 0.5 4.1e-13 49.0 0.5 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) RAMP4 PF06624.12 KUM66167.1 - 0.0018 18.3 0.3 0.0039 17.2 0.3 1.4 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 PQQ PF01011.21 KUM66167.1 - 0.18 11.8 1.7 24 5.1 0.1 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat Mg_trans_NIPA PF05653.14 KUM66168.1 - 5.2e-93 311.4 18.4 6.1e-93 311.2 18.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KUM66168.1 - 0.00054 20.1 3.4 0.00054 20.1 3.4 3.3 2 1 1 3 3 3 2 EamA-like transporter family Acyl_transf_3 PF01757.22 KUM66168.1 - 0.0068 15.5 3.5 0.0068 15.5 3.5 2.2 1 1 1 2 2 2 1 Acyltransferase family Gate PF07670.14 KUM66168.1 - 0.13 12.5 8.6 7.5 6.9 2.3 3.6 2 2 1 3 3 3 0 Nucleoside recognition DUF3671 PF12420.8 KUM66168.1 - 2.3 8.3 5.5 0.54 10.4 0.5 2.3 3 0 0 3 3 3 0 Protein of unknown function MreB_Mbl PF06723.13 KUM66169.1 - 0.0067 15.3 0.0 0.067 12.0 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein HSP70 PF00012.20 KUM66169.1 - 0.05 11.8 0.0 0.16 10.1 0.0 1.7 2 0 0 2 2 2 0 Hsp70 protein Methyltransf_32 PF13679.6 KUM66170.1 - 5.4e-22 78.5 0.0 8.4e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KUM66172.1 - 3.1e-10 40.2 0.2 3.1e-10 40.2 0.2 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site SAT PF16073.5 KUM66172.1 - 3.2e-06 27.1 0.1 4.5e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Mito_fiss_reg PF05308.11 KUM66172.1 - 0.087 12.9 1.9 3.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF4470 PF14737.6 KUM66173.1 - 3.3e-22 78.5 0.1 6.2e-22 77.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) DHC_N2 PF08393.13 KUM66175.1 - 0.02 14.0 1.0 0.034 13.2 0.3 1.7 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 APG6_N PF17675.1 KUM66175.1 - 0.098 13.2 6.5 3 8.4 3.8 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Laminin_II PF06009.12 KUM66175.1 - 0.13 12.3 1.5 5.8 6.9 0.7 2.4 2 0 0 2 2 2 0 Laminin Domain II I_LWEQ PF01608.17 KUM66175.1 - 1.8 8.8 5.2 0.3 11.3 1.0 1.8 2 0 0 2 2 2 0 I/LWEQ domain MFS_1 PF07690.16 KUM66176.1 - 4.1e-35 121.3 22.2 2.5e-34 118.7 23.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily ABC2_membrane PF01061.24 KUM66177.1 - 9.9e-83 276.7 49.5 1e-45 155.7 17.2 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KUM66177.1 - 6e-40 136.9 0.0 8e-19 68.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KUM66177.1 - 2.7e-27 94.5 0.2 2.7e-27 94.5 0.2 3.8 4 0 0 4 4 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 KUM66177.1 - 9.8e-08 31.5 39.2 0.00072 18.8 9.8 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KUM66177.1 - 0.00011 22.6 0.8 0.11 12.8 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KUM66177.1 - 0.00011 22.4 0.2 1 9.6 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.6 KUM66177.1 - 0.00012 21.7 0.1 0.0019 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_trans_N PF14510.6 KUM66177.1 - 0.00033 21.2 0.1 0.001 19.6 0.1 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_29 PF13555.6 KUM66177.1 - 0.00049 19.8 1.9 0.085 12.6 0.1 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KUM66177.1 - 0.00061 20.0 0.0 0.29 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KUM66177.1 - 0.0011 18.9 0.3 0.014 15.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 KUM66177.1 - 0.002 18.4 1.5 0.91 9.7 0.5 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KUM66177.1 - 0.0069 16.9 0.0 3.6 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KUM66177.1 - 0.0093 15.9 0.4 1.8 8.5 0.1 2.5 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 KUM66177.1 - 0.013 15.1 2.0 2 8.0 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 KUM66177.1 - 0.017 14.9 0.0 3.2 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KUM66177.1 - 0.04 13.6 0.5 5.8 6.6 0.3 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KUM66177.1 - 0.042 14.3 0.0 11 6.4 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KUM66177.1 - 0.16 11.7 1.2 8.2 6.2 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 KUM66177.1 - 0.17 11.2 0.1 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_17 PF13207.6 KUM66177.1 - 0.21 12.0 0.5 11 6.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KUM66177.1 - 0.36 10.1 1.0 5.6 6.2 0.3 2.3 2 0 0 2 2 2 0 Zeta toxin MFS_1 PF07690.16 KUM66178.1 - 5.1e-32 111.2 58.1 1.7e-29 102.9 48.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KUM66178.1 - 6.4e-08 31.6 33.8 7.3e-05 21.5 14.2 3.1 1 1 2 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.24 KUM66178.1 - 0.00024 20.1 38.3 0.0075 15.2 13.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KUM66178.1 - 0.0017 17.3 19.6 0.16 10.8 0.2 3.2 3 0 0 3 3 3 3 MFS_1 like family Phage_holin_2_3 PF16080.5 KUM66178.1 - 1.8 8.4 7.9 0.86 9.4 0.3 3.6 3 0 0 3 3 3 0 Bacteriophage holin family HP1 IATP PF04568.12 KUM66179.1 - 9.1e-20 70.9 0.5 1.1e-19 70.7 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Abhydrolase_1 PF00561.20 KUM66182.1 - 5.8e-06 26.1 0.1 5.2e-05 23.0 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_2 PF01674.18 KUM66182.1 - 3.9e-05 23.3 0.0 8.1e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_6 PF12697.7 KUM66182.1 - 0.0013 19.4 0.0 0.0016 19.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KUM66182.1 - 0.021 14.1 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF900 PF05990.12 KUM66182.1 - 0.039 13.5 0.0 0.087 12.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.13 KUM66182.1 - 0.076 12.9 0.0 1.4 8.7 0.0 2.1 1 1 0 1 1 1 0 Serine hydrolase Palm_thioest PF02089.15 KUM66182.1 - 0.077 12.8 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Palmitoyl protein thioesterase DUF2974 PF11187.8 KUM66182.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 KUM66182.1 - 0.14 11.9 0.0 5.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KUM66182.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein DUF1749 PF08538.10 KUM66182.1 - 0.24 10.5 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Zn_clus PF00172.18 KUM66183.1 - 1.3e-05 25.2 12.7 2.4e-05 24.3 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM66183.1 - 5.8e-05 22.1 0.0 0.00032 19.6 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain MOEP19 PF16005.5 KUM66184.1 - 0.0061 16.5 0.0 0.045 13.8 0.0 2.1 1 1 1 2 2 2 1 KH-like RNA-binding domain F-box-like PF12937.7 KUM66185.1 - 4.2e-07 29.8 0.0 9.8e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KUM66185.1 - 0.0034 17.2 0.1 0.013 15.3 0.0 2.1 3 0 0 3 3 3 1 F-box domain MIT PF04212.18 KUM66185.1 - 0.058 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 KUM66185.1 - 0.19 11.9 0.2 1.3 9.3 0.2 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat HATPase_c PF02518.26 KUM66187.1 - 5.2e-31 107.5 0.1 1.5e-30 105.9 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 KUM66187.1 - 3e-29 101.2 16.9 2.4e-08 34.3 0.2 6.8 5 3 2 7 7 7 4 HAMP domain Response_reg PF00072.24 KUM66187.1 - 4.6e-28 97.6 0.1 6.8e-27 93.9 0.3 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KUM66187.1 - 1.4e-10 41.0 1.2 6e-10 39.0 0.3 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Syntaxin_2 PF14523.6 KUM66187.1 - 0.00056 20.2 6.3 1 9.7 0.0 4.8 3 1 1 4 4 4 2 Syntaxin-like protein DUF948 PF06103.11 KUM66187.1 - 0.0033 17.7 28.9 41 4.5 5.2 7.1 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF1843 PF08898.10 KUM66187.1 - 0.0035 17.8 1.7 25 5.4 0.0 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) DUF3829 PF12889.7 KUM66187.1 - 0.0077 15.7 1.8 1.4 8.3 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3829) AdHead_fibreRBD PF16812.5 KUM66187.1 - 0.082 12.7 2.9 0.21 11.4 0.0 2.7 3 0 0 3 3 3 0 C-terminal head domain of the fowl adenovirus type 1 long fibre HATPase_c_2 PF13581.6 KUM66187.1 - 0.094 12.7 0.1 2 8.4 0.0 2.9 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain TMF_TATA_bd PF12325.8 KUM66187.1 - 0.63 10.3 10.2 4 7.7 0.5 4.9 5 1 1 6 6 6 0 TATA element modulatory factor 1 TATA binding DUF4795 PF16043.5 KUM66187.1 - 2.5 7.7 9.7 16 5.0 0.7 3.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4795) BORCS6 PF10157.9 KUM66187.1 - 7.1 6.8 8.8 38 4.5 0.0 4.4 3 2 1 4 4 4 0 BLOC-1-related complex sub-unit 6 Cpn60_TCP1 PF00118.24 KUM66188.1 - 3.8e-85 286.4 7.9 5.6e-85 285.8 7.9 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Amidase PF01425.21 KUM66189.1 - 1.3e-37 129.8 3.1 3e-18 66.0 1.9 2.7 2 1 1 3 3 3 2 Amidase Glyco_hydro_32C PF08244.12 KUM66190.1 - 4.1e-24 85.4 4.2 1.1e-23 84.0 4.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 KUM66190.1 - 2.3e-12 47.1 0.0 3.8e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain B3_4 PF03483.17 KUM66191.1 - 1.5e-21 76.8 0.0 2e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 B3/4 domain UCR_14kD PF02271.16 KUM66191.1 - 0.13 12.3 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.27 KUM66192.1 - 4.5e-61 202.8 0.5 3.4e-18 65.4 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF676 PF05057.14 KUM66193.1 - 2e-07 30.8 0.1 2.5e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KUM66193.1 - 7e-05 22.6 0.0 0.0003 20.6 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 KUM66193.1 - 0.00065 19.0 0.4 0.0039 16.5 0.0 2.3 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KUM66193.1 - 0.0013 19.4 0.0 0.0013 19.4 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF4226 PF10774.9 KUM66193.1 - 0.9 9.8 5.6 7.7 6.8 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4226) CorA PF01544.18 KUM66193.1 - 1.6 8.0 10.4 0.43 9.9 6.4 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein ketoacyl-synt PF00109.26 KUM66194.1 - 3.3e-72 243.1 0.0 5.8e-72 242.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KUM66194.1 - 6.1e-60 202.2 0.4 8.8e-59 198.4 0.0 2.6 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KUM66194.1 - 6.4e-58 196.3 0.0 1.2e-57 195.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KUM66194.1 - 3.8e-46 158.0 0.4 3.8e-46 158.0 0.4 2.0 3 0 0 3 3 3 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KUM66194.1 - 4.1e-38 130.0 0.5 5.8e-37 126.3 0.0 3.2 4 0 0 4 4 4 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KUM66194.1 - 9.5e-15 55.0 0.0 1.2e-13 51.5 0.0 2.6 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KUM66194.1 - 1.1e-10 41.2 0.2 4e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_12 PF08242.12 KUM66194.1 - 6.8e-09 36.4 0.0 2.9e-08 34.3 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM66194.1 - 3.3e-07 30.3 0.0 8.5e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KUM66194.1 - 9.1e-07 28.7 0.0 3.2e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_25 PF13649.6 KUM66194.1 - 1.7e-05 25.4 0.0 7.7e-05 23.3 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain SAT PF16073.5 KUM66194.1 - 2.4e-05 24.2 1.5 8.1e-05 22.5 1.5 1.9 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 KUM66194.1 - 3.2e-05 24.2 0.0 8.7e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 KUM66194.1 - 0.00017 22.2 0.0 0.00052 20.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KUM66194.1 - 0.00017 21.1 0.8 0.00032 20.1 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ADH_N PF08240.12 KUM66194.1 - 0.00059 19.7 0.4 0.0017 18.2 0.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_28 PF02636.17 KUM66194.1 - 0.015 14.9 0.0 0.32 10.6 0.0 2.7 2 1 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 KUM66194.1 - 0.016 15.0 0.0 0.049 13.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Sacchrp_dh_NADP PF03435.18 KUM66194.1 - 0.024 14.9 0.0 0.31 11.3 0.0 2.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Ubie_methyltran PF01209.18 KUM66194.1 - 0.025 13.9 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.10 KUM66194.1 - 0.063 13.1 0.2 0.24 11.3 0.2 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Polysacc_synt_2 PF02719.15 KUM66194.1 - 0.081 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 KUM66194.1 - 0.089 12.8 0.0 0.3 11.1 0.0 1.9 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KUM66194.1 - 0.15 13.1 0.0 0.68 11.0 0.0 2.1 2 0 0 2 2 1 0 Zinc-binding dehydrogenase SEO_N PF14576.6 KUM66196.1 - 0.16 11.1 0.2 0.19 10.8 0.2 1.1 1 0 0 1 1 1 0 Sieve element occlusion N-terminus ThrE PF06738.12 KUM66197.1 - 3.7e-76 255.7 22.8 3.2e-70 236.3 5.2 2.4 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KUM66197.1 - 2.6e-12 47.0 9.8 2.6e-12 47.0 9.8 2.9 3 0 0 3 3 3 1 Threonine/Serine exporter, ThrE FSH1 PF03959.13 KUM66199.1 - 6.5e-28 97.8 0.0 7.6e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KUM66199.1 - 0.0058 17.2 0.1 0.011 16.4 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_25 PF13649.6 KUM66200.1 - 1.7e-13 51.1 0.3 1.2e-12 48.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM66200.1 - 1.7e-13 50.7 0.1 2.4e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM66200.1 - 3.5e-11 43.6 0.0 1.1e-10 42.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM66200.1 - 9.8e-11 41.7 0.0 1.8e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM66200.1 - 1e-10 42.2 0.0 2.3e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KUM66200.1 - 1.8e-05 24.2 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KUM66200.1 - 0.0014 18.6 0.0 0.0022 18.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KUM66200.1 - 0.16 11.5 0.0 0.68 9.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Asparaginase_II PF06089.12 KUM66201.1 - 5.3e-56 190.0 0.5 5.7e-56 189.9 0.5 1.0 1 0 0 1 1 1 1 L-asparaginase II Pyr_redox_2 PF07992.14 KUM66202.1 - 9.3e-22 77.6 0.0 1.7e-21 76.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM66202.1 - 5e-06 25.9 0.1 0.00013 21.2 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KUM66202.1 - 5e-05 22.7 0.6 0.021 14.1 0.1 3.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KUM66202.1 - 0.00054 18.8 0.2 0.0051 15.6 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 KUM66202.1 - 0.0012 18.1 0.1 0.0029 16.9 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KUM66202.1 - 0.0023 17.6 1.5 0.0054 16.3 1.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KUM66202.1 - 0.004 17.3 0.1 0.012 15.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KUM66202.1 - 0.0058 15.7 0.2 0.012 14.7 0.2 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KUM66202.1 - 0.022 14.0 0.1 0.038 13.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KUM66202.1 - 0.043 13.8 0.5 0.22 11.5 0.1 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KUM66202.1 - 0.097 11.5 0.1 0.23 10.2 0.1 1.6 1 0 0 1 1 1 0 Tryptophan halogenase DUF3716 PF12511.8 KUM66203.1 - 2e-07 30.9 6.2 3.1e-07 30.3 6.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) p450 PF00067.22 KUM66204.1 - 2.3e-52 178.3 0.0 2.6e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ALO PF04030.14 KUM66207.1 - 3.2e-89 299.2 0.1 4.7e-89 298.7 0.1 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KUM66207.1 - 1.6e-31 108.9 0.1 2.5e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Syja_N PF02383.18 KUM66208.1 - 6.4e-92 308.3 0.0 9.5e-92 307.7 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KUM66208.1 - 6.6e-38 129.0 0.0 1.3e-37 128.0 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase CDP-OH_P_transf PF01066.21 KUM66209.1 - 5.7e-13 49.4 0.5 5.7e-13 49.4 0.5 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Dsh_C PF12316.8 KUM66209.1 - 0.046 14.1 4.1 0.055 13.9 0.8 2.1 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal BHD_2 PF10404.9 KUM66209.1 - 0.2 12.6 0.6 0.2 12.6 0.6 2.0 1 1 1 2 2 2 0 Rad4 beta-hairpin domain 2 E1-E2_ATPase PF00122.20 KUM66211.1 - 3.2e-33 114.8 17.7 9.5e-28 96.9 0.1 3.2 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KUM66211.1 - 9.8e-27 93.8 10.8 9.8e-27 93.8 10.8 2.9 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KUM66211.1 - 1.1e-17 63.5 0.0 2.6e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KUM66211.1 - 6.3e-17 62.6 0.2 9.1e-16 58.8 0.2 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KUM66211.1 - 1.5e-15 57.0 0.0 3e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KUM66211.1 - 9.7e-05 22.2 0.6 0.00092 19.0 0.6 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Zn_clus PF00172.18 KUM66212.1 - 3e-08 33.6 13.9 5.7e-08 32.7 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ PF00226.31 KUM66213.1 - 1.6e-16 60.2 0.6 4.4e-16 58.8 0.6 1.8 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KUM66213.1 - 9.4e-09 34.8 0.0 0.00012 21.4 0.0 2.1 2 0 0 2 2 2 2 Sec63 Brl domain DUF4045 PF13254.6 KUM66214.1 - 1.7e-109 367.3 66.7 1.7e-66 225.6 39.2 5.8 3 2 2 5 5 5 2 Domain of unknown function (DUF4045) Gelsolin PF00626.22 KUM66214.1 - 1.1e-09 38.1 0.0 0.0016 18.3 0.0 3.7 3 0 0 3 3 3 3 Gelsolin repeat adh_short_C2 PF13561.6 KUM66216.1 - 8.5e-59 198.9 2.7 9.8e-59 198.7 2.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM66216.1 - 1.9e-42 144.9 3.1 2.4e-42 144.6 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM66216.1 - 1.9e-14 54.0 1.4 2.5e-14 53.6 1.4 1.1 1 0 0 1 1 1 1 KR domain NAD_Gly3P_dh_N PF01210.23 KUM66216.1 - 0.0016 18.5 0.8 0.0038 17.2 0.9 1.6 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus THF_DHG_CYH_C PF02882.19 KUM66216.1 - 0.0081 15.5 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Iso_dh PF00180.20 KUM66218.1 - 3.4e-129 431.0 0.0 3.8e-129 430.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aldo_ket_red PF00248.21 KUM66219.1 - 1.3e-64 218.2 0.0 1.9e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SBD_N PF07005.11 KUM66219.1 - 3.3e-57 193.8 0.0 5.9e-57 193.0 0.0 1.4 1 0 0 1 1 1 1 Sugar-binding N-terminal domain NBD_C PF17042.5 KUM66219.1 - 6.6e-38 130.9 0.1 2.1e-37 129.2 0.0 1.9 2 0 0 2 2 2 1 Nucleotide-binding C-terminal domain FMN_dh PF01070.18 KUM66220.1 - 7.8e-112 373.7 0.1 9.3e-112 373.5 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KUM66220.1 - 1.6e-05 24.3 0.1 3.6e-05 23.1 0.1 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KUM66220.1 - 3.5e-05 23.0 0.5 8.9e-05 21.6 0.5 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KUM66220.1 - 0.00089 18.6 2.0 0.025 13.9 0.1 2.6 2 1 0 3 3 3 1 Thiazole biosynthesis protein ThiG NMO PF03060.15 KUM66220.1 - 0.019 14.4 0.7 0.031 13.7 0.3 1.4 1 1 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 KUM66220.1 - 0.024 14.1 0.1 0.14 11.6 0.0 2.1 2 1 1 3 3 3 0 Histidine biosynthesis protein Cyt-b5 PF00173.28 KUM66220.1 - 0.09 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Dus PF01207.17 KUM66220.1 - 0.16 11.0 0.1 0.92 8.5 0.0 2.0 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Epimerase PF01370.21 KUM66221.1 - 1.8e-15 57.0 0.0 2.3e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM66221.1 - 2.9e-09 36.8 0.0 4.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KUM66221.1 - 5.4e-09 35.4 0.0 8.3e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KUM66221.1 - 3e-06 26.6 0.0 2.7e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KUM66221.1 - 3.9e-05 23.0 0.0 0.072 12.3 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein KR PF08659.10 KUM66221.1 - 9.2e-05 22.4 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KUM66221.1 - 0.00046 19.7 0.0 0.00093 18.7 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase Ldh_1_N PF00056.23 KUM66221.1 - 0.0051 16.9 0.0 0.0079 16.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KUM66221.1 - 0.06 12.5 0.0 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Hydrophobin PF01185.18 KUM66222.1 - 0.0013 19.3 6.9 0.002 18.7 6.9 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.18 KUM66222.1 - 0.076 13.4 2.0 0.076 13.4 2.0 2.3 2 0 0 2 2 2 0 Granulin Hydrophobin PF01185.18 KUM66223.1 - 0.0041 17.7 7.0 0.0063 17.1 7.0 1.3 1 0 0 1 1 1 1 Fungal hydrophobin CbiZ PF01955.18 KUM66223.1 - 0.024 14.7 0.6 0.039 14.0 0.6 1.2 1 0 0 1 1 1 0 Adenosylcobinamide amidohydrolase Granulin PF00396.18 KUM66223.1 - 0.11 12.9 2.4 0.11 12.9 2.4 2.4 2 0 0 2 2 2 0 Granulin TPP_enzyme_N PF02776.18 KUM66224.1 - 7.4e-27 94.0 0.0 1.2e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KUM66224.1 - 9.3e-16 58.0 0.0 1.9e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KUM66224.1 - 9.6e-16 57.8 0.0 1.8e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain ANAPC10 PF03256.16 KUM66225.1 - 5.2e-43 146.8 0.0 8.3e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Wzy_C PF04932.15 KUM66226.1 - 3.8 7.1 6.2 1.3 8.7 0.3 2.2 1 1 1 2 2 2 0 O-Antigen ligase bZIP_1 PF00170.21 KUM66227.1 - 1.9e-06 27.9 7.2 4.7e-06 26.6 5.5 2.1 1 1 1 2 2 2 1 bZIP transcription factor Lzipper-MIP1 PF14389.6 KUM66227.1 - 0.0057 16.9 3.4 0.62 10.4 0.1 2.5 1 1 1 2 2 2 2 Leucine-zipper of ternary complex factor MIP1 Ribosomal_S20p PF01649.18 KUM66227.1 - 0.0064 17.1 2.6 0.0092 16.6 2.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S20 bZIP_2 PF07716.15 KUM66227.1 - 0.012 15.6 10.8 0.65 10.1 11.4 2.3 1 1 1 2 2 2 0 Basic region leucine zipper BicD PF09730.9 KUM66227.1 - 0.023 13.2 4.3 0.031 12.7 4.3 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D DUF4618 PF15397.6 KUM66227.1 - 0.051 13.0 3.9 0.076 12.4 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) FlxA PF14282.6 KUM66227.1 - 0.068 13.2 5.4 0.19 11.7 5.4 1.8 1 0 0 1 1 1 0 FlxA-like protein Guanylate_kin PF00625.21 KUM66227.1 - 0.073 12.8 1.6 0.11 12.1 1.6 1.2 1 0 0 1 1 1 0 Guanylate kinase LPP PF04728.13 KUM66227.1 - 0.092 13.1 0.9 6 7.3 0.2 3.2 3 1 0 3 3 3 0 Lipoprotein leucine-zipper HAUS4 PF14735.6 KUM66227.1 - 0.14 11.8 3.0 0.21 11.2 3.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Spc7 PF08317.11 KUM66227.1 - 0.39 9.5 6.0 0.54 9.1 6.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 KUM66227.1 - 0.45 10.3 5.4 4.2 7.2 4.1 2.3 1 1 1 2 2 2 0 Septum formation initiator MbeD_MobD PF04899.12 KUM66227.1 - 0.75 9.9 6.1 3.2 7.9 0.1 3.0 2 1 1 3 3 3 0 MbeD/MobD like DUF4094 PF13334.6 KUM66227.1 - 7.5 7.1 5.9 1.4 9.4 1.8 1.9 3 0 0 3 3 1 0 Domain of unknown function (DUF4094) Acyl-CoA_dh_1 PF00441.24 KUM66228.1 - 9.6e-39 133.0 7.3 1.6e-38 132.3 7.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KUM66228.1 - 3.9e-27 95.1 1.5 8.6e-27 94.0 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KUM66228.1 - 5.2e-25 87.5 0.0 1.3e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KUM66228.1 - 3.1e-16 59.8 4.1 5.2e-16 59.1 4.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KUM66228.1 - 0.0063 16.2 0.0 0.015 14.9 0.0 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal GWT1 PF06423.12 KUM66229.1 - 8.7e-42 142.8 3.5 2.2e-39 135.0 2.3 2.4 2 0 0 2 2 2 2 GWT1 DUF4818 PF16089.5 KUM66229.1 - 0.035 14.6 1.3 0.1 13.1 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4818) DEAD PF00270.29 KUM66230.1 - 1.6e-39 135.5 0.0 2.5e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM66230.1 - 2.7e-22 79.2 0.0 2.1e-21 76.3 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KUM66230.1 - 6.3e-05 22.3 0.0 9.1e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KUM66230.1 - 0.00052 20.1 0.0 0.00088 19.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KUM66230.1 - 0.00093 19.6 0.0 0.0019 18.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KUM66230.1 - 0.066 13.1 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Helicase UvrD-helicase PF00580.21 KUM66230.1 - 0.075 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain p450 PF00067.22 KUM66231.1 - 3.4e-32 111.8 0.0 4.8e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Amidase PF01425.21 KUM66232.1 - 2.7e-84 283.7 0.0 6.8e-84 282.4 0.0 1.6 1 1 0 1 1 1 1 Amidase Cyt-b5 PF00173.28 KUM66233.1 - 6e-19 68.0 0.2 6e-19 68.0 0.2 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KUM66233.1 - 1.3e-12 48.2 19.5 2.6e-12 47.3 19.0 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KUM66233.1 - 0.0039 17.4 0.1 0.0087 16.3 0.1 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region ATP-synt_I PF03899.15 KUM66233.1 - 0.19 12.1 4.6 0.63 10.4 0.1 2.2 2 0 0 2 2 2 0 ATP synthase I chain OMPdecase PF00215.24 KUM66234.1 - 0.00028 20.6 0.0 0.0012 18.5 0.0 1.9 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family PP2C PF00481.21 KUM66235.1 - 4.6e-32 111.7 0.0 1.7e-26 93.4 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KUM66235.1 - 0.032 13.9 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C RRM_1 PF00076.22 KUM66236.1 - 2.5e-43 145.7 0.8 4.2e-22 77.7 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KUM66236.1 - 1.8e-22 80.2 0.9 4.5e-22 78.9 0.1 2.2 2 1 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 KUM66236.1 - 0.00014 21.7 0.0 0.021 14.7 0.0 2.8 3 0 0 3 3 3 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KUM66236.1 - 0.0089 16.3 0.2 0.6 10.3 0.2 2.7 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 KUM66236.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KUM66236.1 - 0.016 15.2 0.1 0.08 13.0 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif Limkain-b1 PF11608.8 KUM66236.1 - 0.026 14.6 0.0 0.5 10.5 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 Nup35_RRM_2 PF14605.6 KUM66236.1 - 0.066 13.2 0.0 14 5.8 0.0 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KUM66236.1 - 0.085 13.0 0.0 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif Adap_comp_sub PF00928.21 KUM66237.1 - 4.2e-18 65.7 0.0 6.3e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KUM66237.1 - 1.5e-07 31.4 0.1 2.6e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KUM66237.1 - 0.00064 19.2 0.0 0.003 17.1 0.0 1.9 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain RPM2 PF08579.11 KUM66237.1 - 0.0036 17.7 0.2 0.0072 16.7 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) DUF2420 PF10336.9 KUM66238.1 - 4.4e-18 65.3 0.1 1e-17 64.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Integrase_H2C2 PF17921.1 KUM66240.1 - 4.8e-07 29.8 0.1 7.6e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_4 PF13420.7 KUM66241.1 - 4e-06 27.1 0.0 1.7e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Arf PF00025.21 KUM66242.1 - 2.8e-65 219.0 1.7 3.2e-65 218.9 1.7 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KUM66242.1 - 4.6e-12 45.8 0.0 5.3e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM66242.1 - 5.1e-12 46.1 0.1 7.4e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KUM66242.1 - 8.2e-12 44.9 2.7 9.8e-07 28.2 0.8 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KUM66242.1 - 2e-11 43.7 0.0 2.4e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KUM66242.1 - 2.1e-07 30.5 0.0 2.6e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KUM66242.1 - 2.7e-07 30.7 0.0 3.8e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KUM66242.1 - 2.5e-06 27.2 0.0 0.00011 21.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 KUM66242.1 - 0.0069 16.3 0.3 0.13 12.2 0.1 2.0 2 0 0 2 2 2 1 NACHT domain HCV_NS1 PF01560.17 KUM66242.1 - 0.0086 14.8 0.1 0.01 14.6 0.1 1.1 1 0 0 1 1 1 1 Hepatitis C virus non-structural protein E2/NS1 cobW PF02492.19 KUM66242.1 - 0.01 15.4 0.1 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 KUM66242.1 - 0.068 12.7 0.2 0.21 11.1 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Pkinase PF00069.25 KUM66243.1 - 6.2e-53 179.9 0.0 3.8e-50 170.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KUM66243.1 - 6.6e-32 110.8 0.0 2.2e-31 109.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KUM66243.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KUM66243.1 - 0.0026 16.9 0.1 0.0046 16.1 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KUM66243.1 - 0.0032 16.3 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KUM66243.1 - 0.023 13.6 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Meth_synt_2 PF01717.18 KUM66244.1 - 9.1e-08 31.7 0.0 1.7e-06 27.6 0.0 2.3 2 1 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KUM66244.1 - 0.16 11.4 0.0 0.66 9.4 0.0 1.9 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain DUF357 PF04010.13 KUM66244.1 - 0.71 10.0 3.3 2 8.5 3.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF357) Pyr_redox_2 PF07992.14 KUM66245.1 - 1.4e-53 182.0 0.2 2.4e-53 181.3 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KUM66245.1 - 1.2e-31 109.2 0.1 2.3e-31 108.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KUM66245.1 - 2.3e-14 53.7 0.2 2.3e-14 53.7 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM66245.1 - 1.5e-08 34.2 0.1 2e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM66245.1 - 0.00013 21.3 0.0 0.00025 20.3 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 KUM66245.1 - 0.016 15.1 0.1 0.042 13.7 0.1 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KUM66245.1 - 0.11 11.8 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KUM66245.1 - 0.46 9.5 4.4 13 4.7 1.0 2.9 3 0 0 3 3 3 0 FAD binding domain Neurokinin_B PF03823.14 KUM66246.1 - 0.049 13.7 0.1 0.085 12.9 0.1 1.4 1 0 0 1 1 1 0 Neurokinin B Amidohydro_2 PF04909.14 KUM66247.1 - 2.3e-23 83.4 0.0 2.7e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Sugar_tr PF00083.24 KUM66248.1 - 2.4e-63 214.6 9.5 1.6e-55 188.8 7.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KUM66248.1 - 1.3e-05 24.3 22.9 0.00086 18.3 4.4 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily Dynein_AAA_lid PF17852.1 KUM66248.1 - 0.26 11.3 0.0 0.26 11.3 0.0 1.9 3 0 0 3 3 3 0 Dynein heavy chain AAA lid domain Fungal_trans PF04082.18 KUM66249.1 - 4e-23 81.8 0.1 6.6e-23 81.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM66249.1 - 2.1e-10 40.5 8.5 3.6e-10 39.8 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 KUM66250.1 - 5.3e-46 156.6 0.3 9.8e-46 155.7 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KUM66250.1 - 6e-31 107.1 0.3 3.6e-29 101.4 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 KUM66250.1 - 0.0028 16.5 2.3 0.0068 15.2 0.2 2.5 2 1 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 HEAT_EZ PF13513.6 KUM66251.1 - 4.9e-34 116.3 2.1 6.2e-16 58.5 0.1 8.4 7 1 1 8 8 8 5 HEAT-like repeat HEAT PF02985.22 KUM66251.1 - 4.7e-20 70.0 17.0 0.0011 19.0 0.0 11.5 13 0 0 13 13 13 5 HEAT repeat HEAT_2 PF13646.6 KUM66251.1 - 5.6e-17 61.9 0.1 2.3e-05 24.7 0.0 7.6 4 2 4 8 8 8 5 HEAT repeats Cnd1 PF12717.7 KUM66251.1 - 8.9e-13 48.6 0.8 4.3e-06 26.9 0.0 4.7 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KUM66251.1 - 1.1e-09 37.4 0.1 0.0016 17.1 0.0 3.4 3 1 0 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KUM66251.1 - 2e-08 34.7 0.4 0.41 11.3 0.0 6.3 4 3 5 9 9 9 3 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KUM66251.1 - 9.8e-06 24.9 3.0 4 6.5 0.0 5.7 3 2 2 6 6 6 2 RNAPII transcription regulator C-terminal IBN_N PF03810.19 KUM66251.1 - 1.8e-05 24.5 0.2 0.0025 17.7 0.0 3.7 3 1 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.8 KUM66251.1 - 0.00039 20.1 0.5 7.5 6.1 0.0 5.8 4 3 0 4 4 4 1 CLASP N terminal HEAT_PBS PF03130.16 KUM66251.1 - 0.0031 18.0 0.3 18 6.3 0.0 4.9 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat Arm PF00514.23 KUM66251.1 - 0.005 16.8 1.7 4.3 7.5 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.9 KUM66251.1 - 0.015 13.9 0.0 0.038 12.5 0.0 1.7 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Tti2 PF10521.9 KUM66251.1 - 0.044 13.3 0.8 14 5.2 0.0 3.7 4 0 0 4 4 4 0 Tti2 family DUF3437 PF11919.8 KUM66251.1 - 0.054 13.4 0.1 3.3 7.7 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) DUF1708 PF08101.11 KUM66251.1 - 0.079 12.1 0.2 0.2 10.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1708) TIP120 PF08623.10 KUM66251.1 - 0.093 12.5 0.0 17 5.1 0.0 3.7 4 1 0 4 4 4 0 TATA-binding protein interacting (TIP20) RIX1 PF08167.12 KUM66251.1 - 0.14 11.9 0.1 7.8 6.2 0.0 3.6 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis DUF4612 PF15389.6 KUM66251.1 - 0.2 12.8 2.0 1.4 10.0 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) ptaRNA1_toxin PF12703.7 KUM66252.1 - 0.19 11.8 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system Mg_trans_NIPA PF05653.14 KUM66253.1 - 1.2e-103 346.3 18.6 1.4e-103 346.0 18.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KUM66253.1 - 0.00033 20.8 8.8 0.00033 20.8 8.8 3.3 3 0 0 3 3 3 3 EamA-like transporter family Sugar_tr PF00083.24 KUM66254.1 - 9.8e-102 341.1 15.5 1.2e-101 340.9 15.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM66254.1 - 7.6e-23 81.0 18.9 7.6e-23 81.0 18.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily BNR_2 PF13088.6 KUM66255.1 - 1.4e-75 254.1 0.2 1.7e-75 253.9 0.2 1.0 1 0 0 1 1 1 1 BNR repeat-like domain Sortilin-Vps10 PF15902.5 KUM66255.1 - 0.00025 20.0 0.1 0.59 8.8 0.1 3.0 2 1 0 2 2 2 2 Sortilin, neurotensin receptor 3, BNR_4 PF15892.5 KUM66255.1 - 0.0011 18.4 0.0 0.86 8.9 0.0 3.0 3 0 0 3 3 3 2 BNR repeat-containing family member BNR PF02012.20 KUM66255.1 - 0.0012 18.5 24.3 0.32 11.2 0.2 5.6 5 0 0 5 5 5 3 BNR/Asp-box repeat PSII_BNR PF14870.6 KUM66255.1 - 0.0013 18.1 2.2 0.011 15.0 0.1 2.6 3 1 0 3 3 3 1 Photosynthesis system II assembly factor YCF48 HIG_1_N PF04588.13 KUM66256.1 - 1.7e-05 24.9 0.5 2.6e-05 24.3 0.5 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF3683 PF12447.8 KUM66256.1 - 0.028 14.5 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) Aldo_ket_red PF00248.21 KUM66257.1 - 5e-47 160.5 0.0 1.7e-45 155.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SPRY PF00622.28 KUM66258.1 - 8.9e-19 67.8 0.0 1.5e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Peptidase_M24 PF00557.24 KUM66259.1 - 1e-57 195.2 0.0 1.4e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KUM66259.1 - 4.4e-23 81.3 0.0 8.2e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Terpene_synth_C PF03936.16 KUM66260.1 - 7.6e-06 25.5 0.1 1.4e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF2937 PF11157.8 KUM66260.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) PDEase_II PF02112.15 KUM66261.1 - 5.7e-52 176.9 0.0 2.1e-25 89.6 0.0 3.0 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 KUM66261.1 - 0.0007 19.7 0.2 0.0017 18.4 0.2 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KUM66261.1 - 0.0016 18.0 0.0 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DHDPS PF00701.22 KUM66262.1 - 5.4e-43 146.8 0.0 7e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Zn_clus PF00172.18 KUM66263.1 - 7.4e-09 35.6 6.9 1.3e-08 34.8 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM66263.1 - 0.061 12.3 0.2 0.18 10.8 0.2 1.8 1 1 0 1 1 1 0 Fungal specific transcription factor domain Fungal_trans PF04082.18 KUM66264.1 - 6.6e-22 77.8 0.8 1.1e-21 77.0 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM66264.1 - 3.5e-05 23.8 16.2 9.6e-05 22.4 16.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metaviral_G PF09595.10 KUM66264.1 - 0.026 14.6 0.6 0.087 12.9 0.6 1.8 1 0 0 1 1 1 0 Metaviral_G glycoprotein DUF3782 PF12644.7 KUM66264.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Uds1 PF15456.6 KUM66266.1 - 5.6e-45 152.7 0.2 5.6e-45 152.7 0.2 7.9 4 2 1 6 6 6 1 Up-regulated During Septation HR1 PF02185.16 KUM66266.1 - 0.00035 20.6 0.0 0.00035 20.6 0.0 7.9 6 2 2 8 8 8 1 Hr1 repeat ADIP PF11559.8 KUM66266.1 - 0.011 15.9 10.4 0.011 15.9 10.4 8.7 3 1 3 8 8 8 0 Afadin- and alpha -actinin-Binding DUF1192 PF06698.11 KUM66266.1 - 0.16 12.1 0.1 0.16 12.1 0.1 7.8 6 1 2 8 8 8 0 Protein of unknown function (DUF1192) L27 PF02828.16 KUM66266.1 - 0.31 10.8 11.6 22 4.9 0.1 5.6 5 0 0 5 5 5 0 L27 domain Transcrip_act PF04949.13 KUM66266.1 - 0.79 9.6 37.3 0.47 10.3 3.1 6.0 1 1 4 5 5 5 0 Transcriptional activator DUF4407 PF14362.6 KUM66266.1 - 1.1 8.5 86.7 0.14 11.5 14.9 5.9 2 1 3 5 5 5 0 Domain of unknown function (DUF4407) GIT_CC PF16559.5 KUM66266.1 - 1.6 8.7 36.0 4.7 7.2 0.4 9.5 8 2 3 11 11 11 0 GIT coiled-coil Rho guanine nucleotide exchange factor Nup88 PF10168.9 KUM66266.1 - 7.1 4.3 46.8 0.043 11.6 15.0 3.6 3 1 0 4 4 4 0 Nuclear pore component PH_10 PF15411.6 KUM66267.1 - 2.9e-40 137.4 0.0 7e-40 136.1 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 KUM66267.1 - 4.1e-34 116.7 0.0 8.2e-34 115.7 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 KUM66267.1 - 3.3e-25 89.4 3.4 6e-25 88.5 3.4 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 KUM66267.1 - 3.5e-08 33.3 0.1 8.4e-08 32.0 0.1 1.7 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.32 KUM66268.1 - 1.4e-29 101.7 15.8 3.6e-05 24.4 0.0 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.7 KUM66268.1 - 3.3e-10 39.7 1.1 6.6e-10 38.7 1.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KUM66268.1 - 3.6e-07 29.9 0.2 7.2e-07 28.9 0.2 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KUM66268.1 - 0.00024 19.9 1.9 1.5 7.4 0.2 3.4 3 0 0 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KUM66268.1 - 0.00094 19.4 0.3 8.3 6.8 0.1 3.8 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain zf-C2H2 PF00096.26 KUM66269.1 - 1.8e-17 62.7 40.1 3.7e-05 23.9 5.0 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KUM66269.1 - 7.5e-15 54.6 29.1 3.3e-05 24.1 0.7 4.7 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KUM66269.1 - 7e-06 26.4 36.0 0.092 13.6 3.8 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger TFIIA PF03153.13 KUM66269.1 - 0.048 13.7 32.0 0.058 13.4 32.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt5_N PF11942.8 KUM66269.1 - 0.13 13.2 5.1 0.29 12.1 5.1 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal zf-C2H2_8 PF15909.5 KUM66269.1 - 0.17 12.2 14.2 0.71 10.2 1.2 3.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon Presenilin PF01080.17 KUM66269.1 - 0.89 8.3 6.2 1.1 7.9 6.2 1.2 1 0 0 1 1 1 0 Presenilin DUF4129 PF13559.6 KUM66270.1 - 1.1e-05 25.6 0.1 3.2e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) NICE-3 PF07406.11 KUM66270.1 - 1.3e-05 25.3 0.1 0.00043 20.3 0.0 2.1 2 0 0 2 2 2 1 NICE-3 protein OppC_N PF12911.7 KUM66270.1 - 2.4 8.2 5.3 16 5.6 1.5 2.5 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Suc_Fer-like PF06999.12 KUM66271.1 - 5.3e-69 232.0 0.0 6.6e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like NTP_transferase PF00483.23 KUM66272.1 - 2e-53 181.5 0.0 3.8e-53 180.6 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KUM66272.1 - 2.6e-14 52.3 11.3 7.9e-11 41.2 4.4 4.0 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KUM66272.1 - 7.4e-10 39.4 0.0 1.1e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KUM66272.1 - 3.4e-06 26.7 2.7 3.4e-06 26.7 2.7 3.1 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KUM66272.1 - 0.005 15.0 0.4 0.0074 14.5 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.19 KUM66272.1 - 0.18 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase adh_short PF00106.25 KUM66273.1 - 1.5e-10 40.9 0.0 1.2e-05 24.9 0.0 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM66273.1 - 0.012 15.2 0.0 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM66273.1 - 0.03 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 KR domain Peptidase_M41 PF01434.18 KUM66275.1 - 5.6e-57 192.7 0.6 1.1e-56 191.8 0.6 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KUM66275.1 - 7.3e-43 146.2 0.0 2.3e-42 144.5 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KUM66275.1 - 1.7e-09 37.3 0.0 4.7e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KUM66275.1 - 1.5e-05 25.0 0.0 4.2e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KUM66275.1 - 4.9e-05 23.8 0.4 0.00077 19.9 0.4 2.7 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KUM66275.1 - 7.9e-05 22.0 3.8 0.00016 21.0 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 KUM66275.1 - 0.00043 20.6 0.1 0.068 13.5 0.1 2.8 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KUM66275.1 - 0.00087 19.1 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KUM66275.1 - 0.0053 16.9 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KUM66275.1 - 0.012 16.2 0.0 0.14 12.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KUM66275.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KUM66275.1 - 0.024 14.0 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KUM66275.1 - 0.027 14.1 1.1 0.91 9.1 0.3 2.5 1 1 1 2 2 2 0 AAA domain AAA_2 PF07724.14 KUM66275.1 - 0.027 14.6 0.0 0.095 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 KUM66275.1 - 0.094 13.0 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KUM66275.1 - 0.11 11.8 0.4 1.4 8.2 0.0 2.4 3 0 0 3 3 3 0 KaiC NACHT PF05729.12 KUM66275.1 - 0.12 12.2 0.3 1.9 8.4 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KUM66275.1 - 0.13 11.7 0.1 0.46 10.0 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KUM66275.1 - 0.31 10.3 2.7 0.79 9.0 0.4 2.5 2 1 1 3 3 3 0 Zeta toxin MFS_1 PF07690.16 KUM66276.1 - 0.0073 15.3 0.5 0.01 14.8 0.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FBPase PF00316.20 KUM66277.1 - 5.5e-67 224.9 0.0 7.2e-67 224.5 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Sugar_tr PF00083.24 KUM66278.1 - 1.8e-32 112.8 25.5 1.5e-19 70.3 7.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KUM66278.1 - 3.3e-20 72.3 41.3 2.8e-10 39.7 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2 PF00096.26 KUM66280.1 - 0.0067 16.8 9.7 0.099 13.1 0.1 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM66280.1 - 0.44 11.5 7.0 1.9 9.6 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger SNF2_N PF00176.23 KUM66281.1 - 2.9e-33 115.1 0.1 4e-33 114.6 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KUM66281.1 - 1.3e-14 54.5 0.0 2.4e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KUM66281.1 - 0.0042 16.3 0.2 0.014 14.6 0.0 1.9 3 0 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase SHR-BD PF06650.12 KUM66282.1 - 2.7e-98 328.7 0.0 7.4e-96 320.7 0.0 3.6 3 1 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 KUM66282.1 - 1.9e-92 309.0 10.8 1.6e-87 292.8 0.3 5.4 4 1 1 5 5 5 2 Repeating coiled region of VPS13 VPS13 PF16908.5 KUM66282.1 - 5.5e-77 258.7 0.0 2.9e-75 253.1 0.0 3.5 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KUM66282.1 - 2.6e-74 248.8 3.9 6e-69 231.4 0.3 2.9 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KUM66282.1 - 2e-40 137.5 0.0 6.4e-40 135.9 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KUM66282.1 - 6.5e-07 29.6 0.0 2.5e-06 27.7 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain NAD_binding_8 PF13450.6 KUM66283.1 - 1.6e-11 44.2 0.0 1e-10 41.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KUM66283.1 - 5e-10 38.4 0.5 2.9e-09 35.9 0.5 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KUM66283.1 - 2.7e-09 36.7 0.0 4.1e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM66283.1 - 7.9e-07 28.6 0.2 3.8e-06 26.4 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KUM66283.1 - 1.4e-06 27.7 0.1 0.00093 18.4 0.0 2.0 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KUM66283.1 - 0.00025 21.1 0.1 0.00093 19.2 0.0 2.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KUM66283.1 - 0.0037 17.8 0.4 0.61 10.7 0.0 2.9 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KUM66283.1 - 0.014 14.7 0.2 0.13 11.5 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KUM66283.1 - 0.017 14.2 0.1 0.042 12.9 0.1 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KUM66283.1 - 0.021 14.4 0.1 0.053 13.1 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Aldo_ket_red PF00248.21 KUM66285.1 - 8.4e-71 238.6 0.0 9.9e-71 238.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pex14_N PF04695.13 KUM66286.1 - 1.8 9.2 8.7 0.87 10.2 2.3 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Fungal_trans_2 PF11951.8 KUM66287.1 - 2.8e-07 29.7 0.1 4.6e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM66287.1 - 9.1e-05 22.5 0.8 0.0002 21.4 0.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1422 PF07226.11 KUM66287.1 - 0.023 14.7 0.1 0.042 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) Ino80_Iec3 PF14612.6 KUM66287.1 - 0.058 14.1 0.1 0.085 13.5 0.1 1.2 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling AA_permease_2 PF13520.6 KUM66289.1 - 1.1e-66 225.5 44.7 1.3e-66 225.2 44.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM66289.1 - 2.3e-17 62.8 35.2 3.1e-17 62.3 35.2 1.1 1 0 0 1 1 1 1 Amino acid permease Oxidored_FMN PF00724.20 KUM66291.1 - 8.8e-74 248.8 0.0 1.2e-73 248.3 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 KUM66291.1 - 0.0063 16.3 0.0 0.0094 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1848) AP_endonuc_2 PF01261.24 KUM66291.1 - 0.051 13.0 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Fungal_trans PF04082.18 KUM66293.1 - 0.0003 19.9 0.4 0.0003 19.9 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pectate_lyase PF03211.13 KUM66294.1 - 5e-75 251.5 4.6 6.2e-75 251.2 4.6 1.1 1 0 0 1 1 1 1 Pectate lyase MFS_1 PF07690.16 KUM66295.1 - 6.9e-14 51.5 6.3 1.1e-13 50.9 6.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KUM66295.1 - 6.7e-07 28.5 2.2 1.1e-06 27.8 1.7 1.7 1 1 0 1 1 1 1 MFS_1 like family FGGY_C PF02782.16 KUM66296.1 - 3.9e-72 242.1 1.6 6.6e-72 241.4 1.6 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KUM66296.1 - 8e-62 209.0 0.0 1.1e-61 208.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KUM66296.1 - 0.014 14.9 0.3 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF3429 PF11911.8 KUM66297.1 - 1.2e-42 145.7 12.8 1.2e-42 145.7 12.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3429) DUF3405 PF11885.8 KUM66298.1 - 1.1e-168 562.1 0.2 1.1e-168 562.1 0.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) MFS_1 PF07690.16 KUM66301.1 - 1.3e-24 86.8 31.0 1.3e-24 86.8 31.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KUM66301.1 - 0.071 12.0 8.3 0.021 13.7 1.2 2.6 1 1 1 2 2 2 0 MFS_1 like family UCR_hinge PF02320.16 KUM66302.1 - 4.2e-27 94.1 7.3 4.2e-27 94.1 7.3 1.8 2 1 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein RR_TM4-6 PF06459.12 KUM66302.1 - 0.1 12.4 17.1 0.12 12.2 17.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PRCC PF10253.9 KUM66302.1 - 0.2 12.4 15.3 0.23 12.2 15.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF4045 PF13254.6 KUM66302.1 - 0.4 10.3 19.1 0.48 10.0 19.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) BUD22 PF09073.10 KUM66302.1 - 0.42 9.9 20.9 0.48 9.7 20.9 1.0 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KUM66302.1 - 0.55 8.4 20.7 0.6 8.2 20.7 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4865 PF16157.5 KUM66302.1 - 0.84 9.6 2.4 1.5 8.7 2.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4865) ASD2 PF08687.11 KUM66302.1 - 1.3 8.5 12.2 1.7 8.1 12.2 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 CiPC PF15800.5 KUM66302.1 - 1.7 8.3 8.2 1.9 8.1 8.2 1.1 1 0 0 1 1 1 0 Clock interacting protein circadian CobT PF06213.12 KUM66302.1 - 1.9 7.8 23.9 3.1 7.1 23.9 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SAPS PF04499.15 KUM66302.1 - 2.5 6.8 11.0 2.6 6.7 11.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 KUM66302.1 - 2.6 6.7 15.3 3 6.5 15.3 1.1 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 KUM66302.1 - 2.7 6.9 9.2 3.5 6.5 9.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) LAP1C PF05609.12 KUM66302.1 - 2.9 6.9 15.2 3.3 6.7 15.2 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4746 PF15928.5 KUM66302.1 - 3.7 6.9 25.1 4.6 6.6 25.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Neur_chan_memb PF02932.16 KUM66302.1 - 4.4 7.3 6.2 5.4 7.0 6.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spore_coat_CotO PF14153.6 KUM66302.1 - 5.2 7.0 24.8 7 6.5 24.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Herpes_DNAp_acc PF04929.12 KUM66302.1 - 5.4 5.9 9.6 6 5.7 9.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Mitofilin PF09731.9 KUM66302.1 - 6.4 5.5 22.5 7.4 5.3 22.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CAML PF14963.6 KUM66302.1 - 6.5 6.8 5.9 8.1 6.5 5.9 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand CDC45 PF02724.14 KUM66302.1 - 6.9 4.8 15.3 7.9 4.6 15.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PA26 PF04636.13 KUM66302.1 - 8.2 5.2 10.9 9.8 5.0 10.9 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) NPR3 PF03666.13 KUM66302.1 - 9.2 4.9 11.4 10 4.7 11.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Raftlin PF15250.6 KUM66302.1 - 9.7 4.8 11.9 11 4.6 11.9 1.1 1 0 0 1 1 1 0 Raftlin Prenyltransf PF01255.19 KUM66303.1 - 2.2e-80 269.4 0.0 3.7e-80 268.7 0.0 1.3 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Acyltransferase PF01553.21 KUM66304.1 - 6.8e-09 35.4 0.0 1.4e-07 31.2 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase ABC2_membrane_4 PF12730.7 KUM66304.1 - 0.23 11.4 5.4 3 7.8 0.3 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein Aha1_N PF09229.11 KUM66305.1 - 8.5e-40 136.1 1.4 1.9e-39 135.0 0.8 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KUM66305.1 - 2e-18 66.8 1.3 2.2e-18 66.7 0.3 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Sacchrp_dh_C PF16653.5 KUM66306.1 - 9.7e-92 307.8 0.0 1.8e-91 306.9 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KUM66306.1 - 8.4e-27 94.0 0.7 1.5e-26 93.1 0.7 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KUM66306.1 - 7.2e-09 35.8 0.3 1.5e-08 34.8 0.3 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KUM66306.1 - 3.9e-07 30.1 0.7 5.3e-06 26.5 0.3 2.1 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KUM66306.1 - 0.00052 19.6 0.5 0.00085 18.9 0.5 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KUM66306.1 - 0.00072 18.7 0.1 0.001 18.2 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family IlvN PF07991.12 KUM66306.1 - 0.00099 18.7 0.2 0.0084 15.7 0.1 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KUM66306.1 - 0.0043 17.6 0.2 0.0092 16.5 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KUM66306.1 - 0.019 14.2 0.7 0.029 13.6 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KUM66306.1 - 0.042 14.3 0.3 0.085 13.3 0.3 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.25 KUM66306.1 - 0.08 12.4 0.2 0.15 11.5 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Beta_elim_lyase PF01212.21 KUM66309.1 - 1.9e-38 132.4 0.0 2.2e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KUM66309.1 - 8.8e-06 25.1 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KUM66309.1 - 5.3e-05 22.3 0.0 7.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.19 KUM66309.1 - 0.006 15.4 0.0 0.017 13.9 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Arylsulfotran_2 PF14269.6 KUM66310.1 - 2.4e-42 145.4 0.9 3.5e-42 144.8 0.9 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KUM66310.1 - 1.1e-12 47.6 1.8 4.3e-11 42.3 1.7 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF1180 PF06679.12 KUM66310.1 - 0.033 14.6 0.0 0.058 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) MGC-24 PF05283.11 KUM66310.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin BSMAP PF12280.8 KUM66310.1 - 0.71 10.0 0.0 0.71 10.0 0.0 2.4 3 0 0 3 3 3 0 Brain specific membrane anchored protein NAD_binding_4 PF07993.12 KUM66312.1 - 8.9e-74 247.9 0.0 1.3e-73 247.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KUM66312.1 - 3.1e-67 227.0 0.0 4.8e-67 226.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KUM66312.1 - 7.6e-11 41.9 0.0 2.3e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Condensation PF00668.20 KUM66312.1 - 4.4e-08 32.2 0.0 4e-07 29.1 0.0 2.1 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KUM66312.1 - 4.3e-07 30.2 0.0 8.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM66312.1 - 2.3e-05 25.3 0.0 0.00084 20.3 0.0 3.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 KUM66312.1 - 3.3e-05 23.0 0.0 8e-05 21.8 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KUM66312.1 - 0.002 18.0 0.2 0.042 13.7 0.1 2.5 2 1 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KUM66312.1 - 0.0031 16.7 0.0 0.082 12.0 0.0 2.3 2 0 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KUM66312.1 - 0.19 11.1 0.0 0.39 10.1 0.0 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sulfatase PF00884.23 KUM66314.1 - 4.7e-15 55.8 0.1 7.5e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KUM66314.1 - 0.00019 21.1 0.1 0.0003 20.5 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KUM66314.1 - 0.039 12.6 0.3 0.061 11.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF1501 PF07394.12 KUM66314.1 - 0.09 11.8 2.5 0.067 12.2 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) AAA PF00004.29 KUM66315.1 - 1.7e-17 64.1 0.0 3.7e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KUM66315.1 - 0.031 14.3 0.0 0.076 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KUM66315.1 - 0.035 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KUM66315.1 - 0.04 14.3 0.5 0.48 10.8 0.4 2.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KUM66315.1 - 0.053 13.8 0.4 0.47 10.7 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 KUM66315.1 - 0.059 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain PIG-S PF10510.9 KUM66315.1 - 0.078 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein ATPase PF06745.13 KUM66315.1 - 0.15 11.4 0.2 1.5 8.1 0.1 2.2 2 0 0 2 2 2 0 KaiC Mannosyl_trans2 PF04188.13 KUM66316.1 - 2.2e-53 182.2 12.0 1.1e-51 176.5 12.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) BLM10_mid PF16507.5 KUM66317.1 - 8.5e-205 681.3 0.0 1.6e-204 680.5 0.0 1.5 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KUM66317.1 - 2.6e-29 100.9 0.0 1.7e-28 98.3 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 KUM66317.1 - 1.3e-20 73.4 0.0 3.8e-20 71.9 0.0 1.9 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal CLASP_N PF12348.8 KUM66317.1 - 8e-05 22.3 0.1 0.22 11.1 0.0 2.8 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 KUM66317.1 - 0.018 15.3 0.1 2.1 8.8 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat Aminotran_1_2 PF00155.21 KUM66319.1 - 5e-34 118.1 0.0 6.5e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Fer2_2 PF01799.20 KUM66320.1 - 2.3e-10 40.4 0.1 2.3e-10 40.4 0.1 1.6 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 KUM66320.1 - 3.5e-09 36.5 0.9 1.8e-08 34.2 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TetM_leader PF08076.11 KUM66320.1 - 0.092 12.5 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide Fer2_3 PF13085.6 KUM66320.1 - 0.35 10.9 1.3 0.9 9.6 1.1 1.9 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer2_BFD PF04324.15 KUM66320.1 - 0.69 10.3 4.6 2.9 8.3 0.0 2.7 3 0 0 3 3 3 0 BFD-like [2Fe-2S] binding domain Vps36_ESCRT-II PF11605.8 KUM66321.1 - 0.0009 19.4 0.0 0.08 13.1 0.0 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 Mito_carr PF00153.27 KUM66322.1 - 7.8e-44 147.5 6.9 1.4e-16 60.2 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.28 KUM66323.1 - 3.8e-05 24.1 0.0 6.1 7.4 0.0 3.2 2 1 1 3 3 3 3 CBS domain DUF3602 PF12223.8 KUM66324.1 - 3.5e-20 72.4 10.2 2.9e-13 50.2 1.4 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 KUM66324.1 - 0.1 12.2 7.2 1.5 8.4 6.9 2.3 1 1 0 1 1 1 0 GTP1/OBG MFS_1 PF07690.16 KUM66326.1 - 6.8e-50 170.0 69.4 4.9e-31 107.9 22.4 2.6 3 0 0 3 3 3 2 Major Facilitator Superfamily UNC-93 PF05978.16 KUM66326.1 - 2.2e-08 34.0 2.5 2.2e-08 34.0 2.5 3.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF5336 PF17270.2 KUM66326.1 - 0.01 15.5 0.0 4.2 7.0 0.0 3.0 2 0 0 2 2 2 2 Family of unknown function (DUF5336) DUF2406 PF10295.9 KUM66327.1 - 4.6e-25 88.1 0.5 1.4e-24 86.6 0.1 2.1 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) Glyco_tranf_2_3 PF13641.6 KUM66328.1 - 9e-24 84.6 0.0 1.3e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KUM66328.1 - 1.4e-18 67.5 1.4 1.4e-18 67.5 1.4 2.9 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KUM66328.1 - 1.3e-14 54.4 0.0 2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 KUM66328.1 - 7.9e-14 51.1 5.6 9.2e-10 37.7 0.2 3.0 2 1 2 4 4 4 2 Cellulose synthase Glyco_transf_21 PF13506.6 KUM66328.1 - 4.1e-12 45.9 0.0 6.7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 KUM66328.1 - 0.0025 16.5 0.5 0.023 13.3 0.1 2.2 2 0 0 2 2 2 1 Chitin synthase Zn_clus PF00172.18 KUM66330.1 - 2.4e-08 33.9 10.9 4.8e-08 33.0 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ring_hydroxyl_A PF00848.19 KUM66331.1 - 1.9e-27 96.7 8.1 7.4e-15 55.5 0.3 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) CorC_HlyC PF03471.17 KUM66331.1 - 0.0036 17.3 0.0 0.077 13.0 0.0 2.8 3 0 0 3 3 3 1 Transporter associated domain DIPSY PF11763.8 KUM66331.1 - 0.035 14.3 1.8 0.11 12.6 0.0 2.5 2 1 1 3 3 3 0 Cell-wall adhesin ligand-binding C-terminal Zn_clus PF00172.18 KUM66333.1 - 2.7e-07 30.6 9.8 2.7e-07 30.6 9.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM66333.1 - 6.4e-06 25.4 0.0 1.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ras PF00071.22 KUM66335.1 - 4.2e-55 185.8 0.0 4.9e-55 185.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM66335.1 - 4.3e-21 75.4 0.0 6.5e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM66335.1 - 6.6e-08 32.2 0.0 8.6e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.22 KUM66336.1 - 1.1e-12 47.5 0.0 2.4e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CMS1 PF14617.6 KUM66337.1 - 6.7e-78 261.5 6.0 9.2e-78 261.1 6.0 1.2 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KUM66337.1 - 0.0003 20.6 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase RNA12 PF10443.9 KUM66337.1 - 0.041 12.6 2.9 0.057 12.2 2.9 1.1 1 0 0 1 1 1 0 RNA12 protein DUF1180 PF06679.12 KUM66337.1 - 0.14 12.6 0.9 0.23 11.9 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PP_M1 PF03012.14 KUM66337.1 - 0.21 11.1 5.2 0.6 9.6 5.2 1.6 1 1 1 2 2 2 0 Phosphoprotein Presenilin PF01080.17 KUM66337.1 - 4.8 5.8 4.8 6 5.5 4.8 1.1 1 0 0 1 1 1 0 Presenilin CENP-T_C PF15511.6 KUM66339.1 - 1.9e-31 108.4 0.0 3.4e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KUM66339.1 - 2.8e-08 34.0 0.0 4.6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KUM66339.1 - 0.026 14.9 0.0 0.082 13.3 0.0 1.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 MBA1 PF07961.11 KUM66340.1 - 2e-06 27.0 0.0 3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.15 KUM66340.1 - 0.026 14.6 0.2 0.057 13.5 0.2 1.6 1 1 0 1 1 1 0 Tim44-like domain RhoGAP PF00620.27 KUM66341.1 - 1.6e-32 112.5 0.0 5.9e-32 110.6 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KUM66341.1 - 2.4e-11 43.8 2.4 3e-11 43.4 0.2 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Erp_C PF06780.11 KUM66341.1 - 0.12 12.4 0.2 0.24 11.4 0.2 1.5 1 0 0 1 1 1 0 Erp protein C-terminus T3SS_basalb_I PF17001.5 KUM66341.1 - 1.9 9.1 5.0 9 7.0 0.8 3.1 1 1 2 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI DUF4407 PF14362.6 KUM66341.1 - 2.9 7.2 7.4 4.5 6.5 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V-ATPase_G_2 PF16999.5 KUM66341.1 - 4 7.9 15.3 3.1 8.3 5.3 2.9 2 1 0 3 3 3 0 Vacuolar (H+)-ATPase G subunit Atg14 PF10186.9 KUM66341.1 - 6.9 5.7 8.6 11 5.0 8.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 WD40 PF00400.32 KUM66342.1 - 2e-25 88.5 13.5 3.7e-05 24.4 0.1 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM66342.1 - 3e-14 53.1 5.7 0.00031 21.0 0.2 4.6 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KUM66342.1 - 8.6e-09 35.5 0.1 0.0035 17.2 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KUM66342.1 - 0.028 13.4 0.0 0.1 11.5 0.0 1.9 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein E3_binding PF02817.17 KUM66343.1 - 2.5e-10 40.5 1.5 8.9e-10 38.7 0.3 2.4 2 0 0 2 2 2 1 e3 binding domain Glyco_hydro_62 PF03664.13 KUM66344.1 - 3.6e-147 488.9 10.7 4.1e-147 488.7 10.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 DUF2841 PF11001.8 KUM66346.1 - 1.1e-47 161.2 0.0 1.7e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF2838 PF10998.8 KUM66347.1 - 3.9e-42 143.0 11.2 3.9e-42 143.0 11.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Atg14 PF10186.9 KUM66347.1 - 0.024 13.7 4.1 0.043 12.9 4.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CcmD PF04995.14 KUM66348.1 - 0.041 14.0 0.3 0.14 12.3 0.3 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) SMC_N PF02463.19 KUM66349.1 - 1.9e-51 174.6 24.9 9.4e-50 169.1 24.9 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KUM66349.1 - 1.6e-30 105.8 0.0 6.1e-30 103.9 0.0 2.1 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KUM66349.1 - 4e-09 36.7 21.3 2.8e-05 24.1 0.0 4.7 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KUM66349.1 - 7.6e-08 32.0 0.0 1.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KUM66349.1 - 1.4e-06 28.3 15.1 1.4e-06 28.3 15.1 4.3 3 1 1 4 4 3 1 AAA ATPase domain AAA_23 PF13476.6 KUM66349.1 - 6e-06 26.9 32.5 6e-06 26.9 32.5 6.6 3 2 2 5 5 3 1 AAA domain zf-C4H2 PF10146.9 KUM66349.1 - 0.00066 20.0 14.9 0.00066 20.0 14.9 6.4 3 2 3 6 6 3 1 Zinc finger-containing protein SbcCD_C PF13558.6 KUM66349.1 - 0.0035 17.5 0.0 0.025 14.8 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF4200 PF13863.6 KUM66349.1 - 0.0042 17.5 6.9 0.0042 17.5 6.9 8.4 4 2 4 8 8 6 1 Domain of unknown function (DUF4200) Spc7 PF08317.11 KUM66349.1 - 0.024 13.6 116.2 0.032 13.1 11.9 7.1 3 2 4 7 7 7 0 Spc7 kinetochore protein ABC_tran PF00005.27 KUM66349.1 - 1.1 9.8 0.0 1.1 9.8 0.0 6.6 4 2 2 6 6 6 0 ABC transporter SlyX PF04102.12 KUM66349.1 - 1.2 9.8 51.1 0.14 12.8 0.4 8.4 5 3 2 7 7 7 0 SlyX FPP PF05911.11 KUM66349.1 - 2.8 6.0 92.0 0.016 13.4 38.1 4.1 2 1 2 5 5 5 0 Filament-like plant protein, long coiled-coil VPS11_C PF12451.8 KUM66349.1 - 4 7.7 6.0 5.3 7.3 2.2 3.4 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal AAA_13 PF13166.6 KUM66349.1 - 9.3 4.7 92.0 0.039 12.6 5.7 7.3 3 2 4 7 7 7 0 AAA domain DUF1664 PF07889.12 KUM66349.1 - 9.6 6.3 62.6 0.27 11.3 5.0 8.9 5 3 4 9 9 9 0 Protein of unknown function (DUF1664) DUF1943 PF09172.11 KUM66350.1 - 0.034 13.4 0.8 0.19 10.9 1.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) TFIIA PF03153.13 KUM66350.1 - 7.6 6.4 17.6 11 5.9 17.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_10 PF00331.20 KUM66351.1 - 4.3e-95 318.5 0.0 2.2e-92 309.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 10 SNF2_N PF00176.23 KUM66352.1 - 7.4e-55 186.1 0.6 1.3e-54 185.2 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KUM66352.1 - 1.9e-20 73.3 1.2 7.2e-19 68.2 0.1 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM66352.1 - 2.3e-09 37.5 0.1 8.4e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KUM66352.1 - 9.3e-07 28.3 1.1 4.8e-06 26.0 0.6 2.1 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 KUM66352.1 - 0.00025 20.8 0.0 0.00055 19.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_3 PF12836.7 KUM66352.1 - 0.041 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HDA2-3 PF11496.8 KUM66352.1 - 4.2 6.5 7.9 2 7.5 0.4 3.4 3 1 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 VMA21 PF09446.10 KUM66353.1 - 1.9e-15 56.7 8.5 2.8e-15 56.2 8.5 1.3 1 0 0 1 1 1 1 VMA21-like domain ABC_membrane PF00664.23 KUM66353.1 - 0.026 14.2 0.1 0.031 13.9 0.1 1.0 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF2705 PF10920.8 KUM66353.1 - 0.05 12.9 0.1 0.059 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2705) Pyrophosphatase PF00719.19 KUM66354.1 - 9.5e-58 194.5 0.2 1.2e-57 194.2 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.17 KUM66355.1 - 2.2e-45 155.1 0.0 6e-45 153.7 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Sec20 PF03908.13 KUM66356.1 - 1.2e-15 57.2 1.1 4.4e-15 55.4 1.1 2.1 1 0 0 1 1 1 1 Sec20 V-SNARE PF05008.15 KUM66356.1 - 0.0068 16.8 3.1 0.18 12.2 0.2 3.4 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus RHD3 PF05879.12 KUM66356.1 - 0.0071 14.6 0.3 0.014 13.6 0.0 1.5 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) DUF2523 PF10734.9 KUM66356.1 - 0.53 10.9 4.4 7.1 7.3 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2523) MRP_L53 PF10780.9 KUM66357.1 - 3.3e-18 65.6 0.1 4.4e-18 65.2 0.1 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Zn_clus PF00172.18 KUM66358.1 - 1.7e-07 31.2 8.1 3.3e-07 30.3 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM66358.1 - 3.8e-06 26.0 0.3 6.5e-05 21.9 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Rep_fac_C PF08542.11 KUM66359.1 - 4.7e-20 71.8 0.0 1.3e-19 70.4 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 KUM66359.1 - 3.6e-15 56.5 0.0 1.6e-14 54.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KUM66359.1 - 3.8e-12 46.3 0.0 1.5e-07 31.4 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 KUM66359.1 - 4.9e-09 36.4 0.0 1.1e-08 35.2 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 KUM66359.1 - 8.7e-06 25.6 0.0 6.9e-05 22.6 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KUM66359.1 - 2.6e-05 24.7 0.1 0.0011 19.4 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 KUM66359.1 - 0.0001 22.2 0.1 0.00026 20.9 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 KUM66359.1 - 0.00011 22.4 0.0 0.00035 20.8 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 KUM66359.1 - 0.00015 22.1 0.0 0.00062 20.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KUM66359.1 - 0.0002 20.8 0.0 0.013 14.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KUM66359.1 - 0.003 17.3 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KUM66359.1 - 0.0037 17.3 0.0 0.0096 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KUM66359.1 - 0.0062 16.5 0.1 0.048 13.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 KUM66359.1 - 0.0069 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DNA_pol3_delta PF06144.13 KUM66359.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_19 PF13245.6 KUM66359.1 - 0.012 16.0 0.1 0.07 13.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KUM66359.1 - 0.015 14.8 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KUM66359.1 - 0.016 14.3 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ResIII PF04851.15 KUM66359.1 - 0.063 13.3 0.0 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KUM66359.1 - 0.067 12.9 0.0 0.26 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KUM66359.1 - 0.071 13.7 0.0 0.21 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KUM66359.1 - 0.09 13.0 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KUM66359.1 - 0.11 13.0 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KUM66359.1 - 0.13 12.1 0.0 2.9 7.7 0.0 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DUF4863 PF16155.5 KUM66359.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4863) MFS_1 PF07690.16 KUM66360.1 - 8.7e-09 34.8 27.9 1e-08 34.5 27.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM66360.1 - 0.00017 20.6 16.1 0.00021 20.3 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KUM66360.1 - 0.0068 15.3 7.4 0.018 13.9 7.4 1.6 1 1 0 1 1 1 1 MFS_1 like family Med12 PF09497.10 KUM66361.1 - 2.5e-27 95.0 0.4 5.8e-27 93.8 0.4 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 RRM_1 PF00076.22 KUM66362.1 - 5.8e-11 42.1 0.1 4.2e-07 29.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CIA30 PF08547.12 KUM66363.1 - 3.5e-40 137.7 0.0 3.5e-25 88.9 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Cation_ATPase_N PF00690.26 KUM66363.1 - 0.088 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus SAICAR_synt PF01259.18 KUM66364.1 - 2.6e-100 335.2 0.0 3e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase EOS1 PF12326.8 KUM66365.1 - 1.1e-12 48.2 14.8 1.2e-12 48.2 9.5 2.1 1 1 1 2 2 2 2 N-glycosylation protein SUI1 PF01253.22 KUM66366.1 - 3.2e-28 98.0 3.8 4.2e-28 97.7 3.8 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 GlcNAc-1_reg PF18440.1 KUM66366.1 - 0.07 13.4 0.3 0.11 12.7 0.3 1.3 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain UPF0139 PF03669.13 KUM66368.1 - 8e-06 25.6 1.1 1.1e-05 25.2 1.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) ANAPC5 PF12862.7 KUM66369.1 - 8.5e-32 109.1 6.1 2.6e-31 107.5 6.1 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 KUM66369.1 - 0.0015 19.0 0.4 2.9 8.5 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KUM66369.1 - 0.045 13.9 2.5 94 3.5 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KUM66369.1 - 0.11 12.8 9.1 5.9 7.2 0.5 5.8 4 2 1 6 6 6 0 Tetratricopeptide repeat PP-binding PF00550.25 KUM66369.1 - 0.13 12.7 0.0 0.43 11.0 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site TPR_10 PF13374.6 KUM66369.1 - 2.7 8.0 4.8 38 4.3 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat CLP_protease PF00574.23 KUM66371.1 - 4.7e-75 251.5 0.0 6.2e-75 251.1 0.0 1.1 1 0 0 1 1 1 1 Clp protease Tugs PF17840.1 KUM66371.1 - 0.071 13.3 1.1 0.19 12.0 1.1 1.7 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain DUF908 PF06012.12 KUM66373.1 - 1.3 8.3 5.9 1.5 8.2 5.9 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) adh_short PF00106.25 KUM66374.1 - 2.9e-28 98.7 0.1 2.1e-22 79.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM66374.1 - 3.9e-12 46.2 0.0 8.4e-11 41.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM66374.1 - 8.2e-10 38.9 0.0 2.2e-09 37.5 0.0 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KUM66374.1 - 5.2e-05 22.5 0.1 0.00012 21.3 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Glyco_tran_WecB PF03808.13 KUM66374.1 - 0.0017 18.4 0.0 1.4 8.9 0.0 2.4 2 1 0 2 2 2 2 Glycosyl transferase WecB/TagA/CpsF family Epimerase PF01370.21 KUM66374.1 - 0.0045 16.5 0.0 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SURF1 PF02104.15 KUM66375.1 - 1.3e-40 139.5 0.0 1.8e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 SURF1 family Sas10_Utp3 PF04000.15 KUM66376.1 - 3.3e-17 62.9 0.7 3.3e-17 62.9 0.7 2.3 2 1 0 2 2 2 1 Sas10/Utp3/C1D family Hid1 PF12722.7 KUM66376.1 - 5.7 4.9 14.9 7.1 4.6 14.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2076 PF09849.9 KUM66377.1 - 1.3e-09 38.5 16.7 1.5e-09 38.3 16.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KUM66377.1 - 3.9e-05 23.6 0.9 6.5e-05 22.9 0.9 1.4 1 0 0 1 1 1 1 CHCH domain TFIIA PF03153.13 KUM66377.1 - 4.5 7.2 10.7 5.2 6.9 10.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SET PF00856.28 KUM66378.1 - 8.9e-19 68.5 0.0 1.9e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 SET domain dsDNA_bind PF01984.20 KUM66379.1 - 2.9e-39 133.8 11.6 3.3e-39 133.6 11.6 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Coq4 PF05019.13 KUM66380.1 - 3e-96 321.0 0.0 3.6e-96 320.8 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DUF5345 PF17280.2 KUM66380.1 - 1.1 9.3 3.7 1.8 8.6 3.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Sec2p PF06428.11 KUM66381.1 - 3.4e-29 100.7 15.2 8.4e-29 99.4 15.2 1.7 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p SPATA1_C PF15743.5 KUM66381.1 - 0.018 15.1 4.7 0.018 15.1 4.7 2.2 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus GCN5L1 PF06320.13 KUM66381.1 - 0.95 9.6 9.7 0.55 10.4 6.8 2.0 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Tup_N PF08581.10 KUM66381.1 - 5.1 7.5 10.7 3.6 8.0 1.1 3.0 2 1 0 2 2 2 0 Tup N-terminal Peptidase_M18 PF02127.15 KUM66382.1 - 4.1e-165 549.8 0.0 5.1e-165 549.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) DUF1746 PF08508.10 KUM66383.1 - 1.8e-30 105.6 0.4 2.5e-30 105.2 0.4 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) ADH_zinc_N_2 PF13602.6 KUM66384.1 - 4.4e-13 50.4 0.0 9.6e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KUM66384.1 - 1.8e-09 37.7 0.0 2.9e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM66384.1 - 5.6e-08 32.6 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NUDIX PF00293.28 KUM66385.1 - 1.3e-09 38.2 0.0 2.2e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain LETM1 PF07766.13 KUM66386.1 - 2.5e-100 335.2 0.0 4.7e-100 334.3 0.0 1.4 1 0 0 1 1 1 1 LETM1-like protein Hydrolase_6 PF13344.6 KUM66388.1 - 5.4e-30 103.5 0.0 9.3e-30 102.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KUM66388.1 - 2.6e-14 53.0 0.0 2.2e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KUM66388.1 - 2e-10 41.3 0.0 0.0011 19.3 0.0 2.9 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KUM66388.1 - 2.1e-05 24.7 0.1 0.25 11.4 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PNK3P PF08645.11 KUM66388.1 - 0.094 12.4 0.0 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Acid_phosphat_B PF03767.14 KUM66388.1 - 0.17 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) LAGLIDADG_3 PF14528.6 KUM66388.1 - 0.54 10.6 2.6 0.31 11.4 0.3 1.8 2 0 0 2 2 2 0 LAGLIDADG-like domain TauD PF02668.16 KUM66389.1 - 7.3e-43 147.3 1.0 9.2e-43 147.0 1.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4129 PF13559.6 KUM66389.1 - 0.084 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) MFS_1 PF07690.16 KUM66390.1 - 1.6e-59 201.6 59.3 4.4e-50 170.6 46.8 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM66390.1 - 1.4e-14 53.9 29.1 4.6e-12 45.5 10.5 2.6 1 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KUM66390.1 - 6.4e-11 41.4 13.6 6.4e-11 41.4 13.6 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KUM66390.1 - 6.4e-05 22.0 5.1 6.4e-05 22.0 5.1 2.3 1 1 1 2 2 2 1 MFS_1 like family Methyltransf_25 PF13649.6 KUM66391.1 - 4e-15 56.3 0.0 1.2e-14 54.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM66391.1 - 3.1e-14 53.4 0.0 2.1e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM66391.1 - 1.4e-06 28.2 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KUM66391.1 - 1.7e-06 28.0 0.0 3.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM66391.1 - 2e-06 28.4 0.0 3.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 KUM66391.1 - 0.0039 16.3 0.0 0.0094 15.1 0.0 1.5 2 0 0 2 2 2 1 DREV methyltransferase Ubie_methyltran PF01209.18 KUM66391.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Mito_carr PF00153.27 KUM66392.1 - 5.3e-59 196.2 1.0 5.4e-21 74.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Redoxin PF08534.10 KUM66393.1 - 2e-08 34.1 0.0 2.1e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin UBX PF00789.20 KUM66395.1 - 4e-10 39.8 0.0 8.4e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 KUM66395.1 - 0.027 14.6 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like DUF3255 PF11631.8 KUM66395.1 - 0.041 13.8 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) DAG_kinase_N PF14513.6 KUM66395.1 - 0.18 12.0 1.8 0.32 11.2 1.8 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus SAGA-Tad1 PF12767.7 KUM66395.1 - 1.6 8.4 7.9 0.22 11.3 3.9 1.7 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit ApbA_C PF08546.11 KUM66396.1 - 6.6e-33 113.6 0.0 1e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KUM66396.1 - 9.3e-25 87.0 0.0 3e-24 85.4 0.0 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KUM66396.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 ThiF family DUF3176 PF11374.8 KUM66397.1 - 2e-34 118.0 0.6 4.1e-34 117.0 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) CAP_N PF01213.19 KUM66397.1 - 0.96 8.9 2.6 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Zn_clus PF00172.18 KUM66398.1 - 2.1e-10 40.5 10.2 4.3e-10 39.5 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KUM66398.1 - 1.1e-09 37.8 0.1 1.8e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain POT1 PF02765.17 KUM66399.1 - 3.2e-16 59.4 0.0 9.2e-16 58.0 0.0 1.8 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 HDA2-3 PF11496.8 KUM66400.1 - 2.2e-50 171.5 0.0 3.6e-49 167.5 0.0 2.3 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 KUM66400.1 - 0.06 13.3 0.7 0.16 11.9 0.7 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain GAS PF13851.6 KUM66400.1 - 0.12 11.7 37.8 0.57 9.5 24.2 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMEM192 PF14802.6 KUM66400.1 - 0.13 11.3 2.1 0.26 10.4 2.1 1.5 1 0 0 1 1 1 0 TMEM192 family FMO-like PF00743.19 KUM66401.1 - 8.2e-39 133.4 0.0 6.4e-22 77.7 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KUM66401.1 - 9.1e-13 48.1 0.0 1.7e-09 37.4 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM66401.1 - 1.1e-10 41.7 0.0 5.6e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KUM66401.1 - 3.4e-10 39.6 0.0 1e-06 28.2 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KUM66401.1 - 3e-09 36.5 0.0 7.5e-09 35.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM66401.1 - 6.2e-06 26.4 0.0 2.4e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KUM66401.1 - 7.1e-05 22.2 0.0 0.00062 19.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KUM66401.1 - 9.4e-05 22.1 0.0 0.52 9.8 0.0 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KUM66401.1 - 0.016 13.9 0.2 0.52 9.0 0.0 2.3 3 0 0 3 3 3 0 HI0933-like protein Semialdhyde_dh PF01118.24 KUM66401.1 - 0.13 12.7 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KUM66401.1 - 0.23 12.0 0.7 9.7 6.8 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trs65 PF12735.7 KUM66402.1 - 1.1e-102 343.8 0.1 1.4e-102 343.4 0.1 1.1 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Trp_DMAT PF11991.8 KUM66404.1 - 7.2e-75 252.7 0.0 9.1e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase FF PF01846.19 KUM66405.1 - 1.3e-52 175.8 17.4 4e-16 58.9 1.2 6.7 6 0 0 6 6 6 5 FF domain WW PF00397.26 KUM66405.1 - 1.4e-17 63.4 13.7 1e-08 35.1 1.1 2.6 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 KUM66405.1 - 0.00019 22.0 10.8 0.61 10.8 0.2 4.5 2 1 2 4 4 4 3 p190-A and -B Rho GAPs FF domain Glyco_hyd_101C PF17451.2 KUM66405.1 - 1.2 9.4 7.4 2.6 8.4 0.2 2.8 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Motilin_ghrelin PF04644.12 KUM66405.1 - 7.9 6.4 9.6 5.2 7.0 0.2 3.1 3 0 0 3 3 3 0 Motilin/ghrelin PGK PF00162.19 KUM66406.1 - 3.2e-141 470.7 0.9 3.8e-141 470.4 0.9 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3530 PF12048.8 KUM66406.1 - 0.062 12.7 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DSS1_SEM1 PF05160.13 KUM66407.1 - 1.9e-15 56.6 18.3 5.1e-14 52.1 18.3 2.1 1 1 0 1 1 1 1 DSS1/SEM1 family Mpv17_PMP22 PF04117.12 KUM66408.1 - 4.7e-19 68.4 1.7 6.9e-19 67.8 0.1 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family AMP-binding PF00501.28 KUM66410.1 - 7e-138 459.8 0.0 3.8e-70 236.6 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KUM66410.1 - 4e-69 233.5 0.0 3.2e-34 118.4 0.0 4.0 2 2 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KUM66410.1 - 3.9e-22 78.4 0.5 6.5e-11 42.4 0.0 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM66410.1 - 1.6e-06 28.9 0.0 0.012 16.6 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KUM66411.1 - 2.1e-39 135.4 38.0 2.1e-39 135.4 38.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KUM66411.1 - 1.9e-13 49.8 10.7 2.8e-13 49.2 10.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KUM66411.1 - 5.5e-07 28.8 13.2 5.5e-07 28.8 13.2 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter DUF4064 PF13273.6 KUM66411.1 - 0.15 12.3 11.4 1.9 8.8 1.8 4.8 3 1 2 5 5 5 0 Protein of unknown function (DUF4064) DUF3446 PF11928.8 KUM66412.1 - 0.12 12.7 8.9 0.28 11.5 8.9 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain ERCC3_RAD25_C PF16203.5 KUM66415.1 - 3.4e-124 412.9 1.9 6.1e-124 412.1 1.9 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KUM66415.1 - 5.3e-36 123.6 0.0 1.5e-35 122.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM66415.1 - 5e-16 59.2 0.0 9.6e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KUM66415.1 - 1.8e-13 50.8 0.1 4.2e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KUM66415.1 - 1.1e-09 37.5 0.0 1.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KUM66415.1 - 0.00066 19.5 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KUM66415.1 - 0.0014 17.6 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 CTD_bind PF04818.13 KUM66417.1 - 1.4e-11 45.0 0.0 2.8e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. AA_permease PF00324.21 KUM66418.1 - 5.3e-55 186.9 27.5 6.3e-55 186.6 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KUM66418.1 - 8.6e-19 67.7 31.2 1.1e-18 67.3 31.2 1.0 1 0 0 1 1 1 1 Amino acid permease Serinc PF03348.15 KUM66418.1 - 3.5 6.4 8.6 7.8 5.3 8.6 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) Amino_oxidase PF01593.24 KUM66419.1 - 1.5e-43 149.8 0.1 2.3e-42 145.8 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KUM66419.1 - 4.4e-12 46.1 0.5 8.4e-12 45.2 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KUM66419.1 - 8.4e-08 31.7 0.8 1.3e-07 31.1 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KUM66419.1 - 4.4e-06 26.3 0.2 5.5e-06 26.0 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KUM66419.1 - 4.8e-06 26.4 0.1 5.7e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KUM66419.1 - 5.5e-06 25.4 0.2 1.1e-05 24.3 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KUM66419.1 - 0.00025 20.2 1.4 0.00035 19.8 1.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KUM66419.1 - 0.00031 20.1 0.1 0.00048 19.5 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KUM66419.1 - 0.0017 17.7 0.1 0.0026 17.1 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KUM66419.1 - 0.002 18.6 2.5 0.0023 18.5 0.2 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KUM66419.1 - 0.0024 17.2 0.1 0.0039 16.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KUM66419.1 - 0.0029 16.9 0.8 0.016 14.5 0.6 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KUM66419.1 - 0.14 11.2 0.2 0.23 10.5 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KUM66419.1 - 0.16 11.3 0.1 0.28 10.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.25 KUM66420.1 - 1.1e-18 67.7 0.0 1.3e-18 67.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HEV_ORF1 PF02444.16 KUM66420.1 - 0.049 14.2 1.4 0.086 13.4 1.4 1.4 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) DHHA2 PF02833.14 KUM66421.1 - 2.1e-30 105.8 0.1 1.3e-29 103.2 0.0 2.1 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 KUM66421.1 - 1.9e-07 31.3 0.0 3.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 DHH family Sugar_tr PF00083.24 KUM66422.1 - 2.6e-79 267.2 14.5 3.1e-79 266.9 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM66422.1 - 3.6e-21 75.5 25.7 4.5e-21 75.2 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1290 PF06947.12 KUM66422.1 - 0.37 10.9 4.6 1.2 9.3 0.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1290) Transglut_core PF01841.19 KUM66423.1 - 2.5e-08 34.3 0.0 5.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 KUM66423.1 - 7.2e-08 32.0 0.1 2.1e-07 30.5 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KUM66423.1 - 6.5e-06 25.7 0.0 1.9e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KUM66423.1 - 0.0048 16.7 0.3 0.02 14.7 0.2 2.1 2 0 0 2 2 2 1 Variant SH3 domain SAT PF16073.5 KUM66424.1 - 1.9e-83 279.9 1.1 9.9e-82 274.3 0.0 2.7 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 KUM66424.1 - 5.8e-80 268.5 0.0 9.7e-80 267.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KUM66424.1 - 3e-44 151.8 0.0 1.5e-43 149.5 0.1 2.0 2 1 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KUM66424.1 - 9.6e-34 115.9 0.1 2.5e-33 114.6 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KUM66424.1 - 2.4e-24 85.4 6.2 1.6e-12 47.6 1.4 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 KUM66424.1 - 2.5e-22 80.1 0.0 2.4e-21 76.9 0.0 2.7 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 KUM66424.1 - 2e-05 25.3 0.5 0.00061 20.5 0.2 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 KUM66424.1 - 0.00015 21.2 0.0 0.00038 19.9 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KUM66424.1 - 0.00017 22.0 0.1 0.00061 20.2 0.1 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension MFS_1 PF07690.16 KUM66425.1 - 1.2e-40 139.5 60.4 8.6e-40 136.7 34.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2583 PF10762.9 KUM66425.1 - 0.016 15.6 4.9 1.8 9.0 0.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) DUF3808 PF10300.9 KUM66426.1 - 2.1e-163 544.5 0.5 2.5e-163 544.2 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DUF5098 PF17023.5 KUM66426.1 - 0.0084 15.1 0.1 0.015 14.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5098) AMP-binding PF00501.28 KUM66427.1 - 2.2e-279 925.9 0.0 1.6e-77 260.9 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 KUM66427.1 - 1.4e-248 825.0 0.0 2.8e-56 191.1 0.0 8.5 7 3 0 7 7 7 7 Condensation domain PP-binding PF00550.25 KUM66427.1 - 3.8e-46 155.3 8.9 9.5e-10 38.7 0.2 5.9 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM66427.1 - 3.5e-05 24.7 0.0 2 9.5 0.0 4.5 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain BCDHK_Adom3 PF10436.9 KUM66428.1 - 2e-43 148.1 0.1 7.1e-43 146.2 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KUM66428.1 - 3.2e-06 27.6 0.0 1e-05 26.0 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KUM66428.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase USP7_ICP0_bdg PF12436.8 KUM66429.1 - 2e-85 285.9 2.1 2.6e-85 285.6 0.5 1.9 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KUM66429.1 - 1e-72 244.2 0.4 6.9e-69 231.7 0.0 2.8 2 1 1 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KUM66429.1 - 6.2e-50 170.1 0.7 1.2e-49 169.2 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KUM66429.1 - 5.4e-21 75.5 0.0 1.2e-20 74.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KUM66429.1 - 3.7e-05 23.8 0.0 0.0001 22.4 0.0 1.8 1 0 0 1 1 1 1 MATH domain Rad60-SLD PF11976.8 KUM66429.1 - 0.023 14.5 0.2 0.87 9.5 0.1 3.5 4 1 0 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like PreAtp-grasp PF18604.1 KUM66429.1 - 0.14 11.8 0.1 1.2 8.7 0.0 2.6 3 0 0 3 3 3 0 Pre ATP-grasp domain ABC_tran PF00005.27 KUM66430.1 - 1e-44 152.4 0.0 2.5e-24 86.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KUM66430.1 - 5.5e-35 121.3 28.1 1.3e-29 103.8 11.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KUM66430.1 - 2.6e-11 43.4 0.0 0.0057 16.1 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KUM66430.1 - 1e-08 35.6 0.2 0.0017 18.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KUM66430.1 - 3.8e-08 33.5 0.0 0.52 10.1 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KUM66430.1 - 4e-07 30.6 0.0 0.029 14.8 0.0 3.2 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KUM66430.1 - 4.1e-06 26.8 0.0 0.049 13.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KUM66430.1 - 4.4e-06 26.3 0.1 0.11 11.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region cobW PF02492.19 KUM66430.1 - 2.3e-05 24.1 1.4 0.92 9.1 0.0 3.4 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 KUM66430.1 - 0.00011 22.4 0.3 0.22 11.8 0.1 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KUM66430.1 - 0.00018 21.6 0.1 0.54 10.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KUM66430.1 - 0.00019 20.8 0.1 0.73 9.1 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin ATPase_2 PF01637.18 KUM66430.1 - 0.00046 20.2 0.1 0.71 9.7 0.1 2.4 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KUM66430.1 - 0.00053 19.8 0.1 0.33 10.6 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_33 PF13671.6 KUM66430.1 - 0.00057 20.1 0.0 0.34 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KUM66430.1 - 0.00094 18.9 0.5 0.4 10.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 KUM66430.1 - 0.0018 18.3 0.1 3 7.8 0.0 2.7 2 0 0 2 2 2 2 NACHT domain Dynamin_N PF00350.23 KUM66430.1 - 0.0019 18.3 0.1 0.2 11.7 0.0 2.4 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.18 KUM66430.1 - 0.0021 17.4 0.1 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Septin PF00735.18 KUM66430.1 - 0.0025 17.1 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 2 Septin ATP-synt_ab PF00006.25 KUM66430.1 - 0.0045 16.7 0.1 2.2 7.9 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.6 KUM66430.1 - 0.0052 17.1 0.1 0.78 10.1 0.0 3.1 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KUM66430.1 - 0.0058 17.0 0.0 2.6 8.5 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA PF00004.29 KUM66430.1 - 0.0075 16.7 0.2 3.1 8.2 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KUM66430.1 - 0.0075 16.3 0.0 4.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KUM66430.1 - 0.0093 16.0 0.1 1.6 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DLIC PF05783.11 KUM66430.1 - 0.011 14.7 0.0 3.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_25 PF13481.6 KUM66430.1 - 0.021 14.4 0.0 7.9 6.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain PRK PF00485.18 KUM66430.1 - 0.022 14.5 1.2 0.27 11.0 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family T2SSE PF00437.20 KUM66430.1 - 0.022 13.8 0.4 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.9 KUM66430.1 - 0.032 14.0 1.7 0.84 9.4 0.2 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 KUM66430.1 - 0.037 13.2 0.8 5 6.2 0.1 2.6 2 1 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KUM66430.1 - 0.042 13.6 0.1 0.5 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KUM66430.1 - 0.05 14.1 0.1 3.9 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KUM66430.1 - 0.056 13.2 0.5 13 5.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 KUM66430.1 - 0.074 13.3 0.0 13 6.0 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KUM66430.1 - 0.1 13.1 0.3 0.96 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KUM66430.1 - 0.11 12.2 0.2 13 5.4 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 KUM66430.1 - 0.12 11.8 0.2 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_15 PF13175.6 KUM66430.1 - 0.15 11.7 0.1 0.87 9.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 KUM66430.1 - 0.19 11.1 0.5 21 4.4 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 KUM66430.1 - 0.23 11.5 0.8 20 5.2 0.2 3.1 3 0 0 3 3 3 0 AAA domain MobB PF03205.14 KUM66430.1 - 0.25 11.2 0.7 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IF4E PF01652.18 KUM66431.1 - 1.6e-54 184.0 0.0 2.6e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AAA_16 PF13191.6 KUM66433.1 - 9.8e-10 39.1 2.5 1.1e-07 32.4 0.1 4.7 4 0 0 4 4 4 1 AAA ATPase domain TPR_12 PF13424.6 KUM66433.1 - 1.3e-08 35.0 8.8 0.072 13.4 0.0 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat NACHT PF05729.12 KUM66433.1 - 9.6e-06 25.6 0.2 7.3e-05 22.7 0.2 2.6 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KUM66433.1 - 1.8e-05 25.0 0.2 0.00014 22.1 0.1 2.7 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KUM66433.1 - 0.0059 16.5 0.0 0.0059 16.5 0.0 3.1 4 0 0 4 4 4 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KUM66433.1 - 0.027 14.2 0.0 0.12 12.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KUM66433.1 - 0.069 13.2 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KUM66433.1 - 0.11 13.0 1.1 1.2 9.6 0.0 3.3 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 KUM66433.1 - 0.15 12.6 0.1 4.4 7.9 0.0 3.2 2 1 0 2 2 2 0 AAA domain TPR_10 PF13374.6 KUM66433.1 - 0.27 11.1 5.1 46 4.1 0.0 6.1 8 0 0 8 8 8 0 Tetratricopeptide repeat Phage_GP20 PF06810.11 KUM66433.1 - 9 6.1 10.6 13 5.6 0.3 3.9 4 0 0 4 4 4 0 Phage minor structural protein GP20 SPC22 PF04573.12 KUM66434.1 - 7.3e-39 133.0 0.1 3.2e-28 98.3 0.1 2.2 2 0 0 2 2 2 2 Signal peptidase subunit RRP14 PF15459.6 KUM66434.1 - 8.9 7.0 9.6 14 6.4 2.3 2.5 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Pmp3 PF01679.17 KUM66435.1 - 8.6e-22 77.1 9.6 1.1e-21 76.7 9.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator NapE PF06796.11 KUM66435.1 - 1.2 8.8 3.6 1.5 8.4 3.6 1.2 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE Peptidase_C48 PF02902.19 KUM66436.1 - 6.2e-32 111.2 0.0 2e-31 109.5 0.0 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GGACT PF06094.12 KUM66437.1 - 7.3e-16 58.9 0.1 2.3e-15 57.3 0.1 1.7 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Aldolase_II PF00596.21 KUM66438.1 - 5e-47 160.2 0.1 6.1e-47 160.0 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ApbA PF02558.16 KUM66439.1 - 2.4e-25 89.0 0.0 3.4e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KUM66439.1 - 1.2e-24 86.9 0.0 2.9e-24 85.6 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ThiF PF00899.21 KUM66439.1 - 0.037 13.4 1.2 0.076 12.4 1.2 1.4 1 0 0 1 1 1 0 ThiF family Questin_oxidase PF14027.6 KUM66440.1 - 3.8e-97 325.9 0.0 4.5e-97 325.6 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like Fungal_trans_2 PF11951.8 KUM66441.1 - 2.8e-58 197.6 4.3 4.6e-58 196.9 4.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM66441.1 - 6.3e-07 29.4 12.1 1.1e-06 28.7 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.13 KUM66442.1 - 1.8e-16 61.0 0.0 3.4e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KUM66442.1 - 0.014 14.2 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Glyoxalase_3 PF13468.6 KUM66443.1 - 1e-25 90.9 0.0 1.2e-25 90.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain MLTR_LBD PF17765.1 KUM66444.1 - 0.063 13.4 0.2 5.5 7.1 0.1 2.5 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain CN_hydrolase PF00795.22 KUM66445.1 - 1.8e-43 148.7 0.0 2.4e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KUM66445.1 - 4.2e-14 52.3 0.0 2.6e-13 49.7 0.0 2.3 1 1 0 1 1 1 1 NAD synthase NUDIX-like PF09296.11 KUM66446.1 - 8.1e-20 71.4 0.0 2.7e-19 69.7 0.0 1.9 2 1 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.28 KUM66446.1 - 3.5e-17 62.7 0.1 7.3e-17 61.6 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 KUM66446.1 - 1.6e-06 27.7 1.7 3.5e-06 26.6 1.7 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain MFS_1 PF07690.16 KUM66447.1 - 1.4e-30 106.5 52.5 1.4e-30 106.5 52.5 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM66447.1 - 2e-05 23.6 15.4 2e-05 23.6 15.4 3.9 4 0 0 4 4 4 1 Sugar (and other) transporter DUF2721 PF11026.8 KUM66447.1 - 4.3 7.3 11.0 0.15 12.0 0.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) EMP24_GP25L PF01105.24 KUM66448.1 - 7.5e-47 159.6 4.5 8.5e-47 159.4 4.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GHD PF17834.1 KUM66448.1 - 0.16 12.0 0.3 0.16 12.0 0.3 1.9 2 0 0 2 2 2 0 Beta-sandwich domain in beta galactosidase DUF4748 PF15932.5 KUM66449.1 - 1.6e-19 69.4 1.3 2.4e-19 68.8 1.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4748) PIEZO PF15917.5 KUM66449.1 - 0.009 15.5 0.5 0.011 15.2 0.5 1.0 1 0 0 1 1 1 1 Piezo Ribosomal_L24e PF01246.20 KUM66450.1 - 1.6e-27 95.5 0.2 1.6e-27 95.5 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e Acetyltransf_1 PF00583.25 KUM66451.1 - 3.7e-10 40.1 0.1 4.9e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KUM66451.1 - 9.4e-08 32.1 0.0 1.4e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KUM66451.1 - 9e-07 29.2 0.2 1.3e-06 28.7 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain eIF-1a PF01176.19 KUM66452.1 - 4.2e-22 77.7 0.0 5.9e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF3124 PF11322.8 KUM66452.1 - 0.07 13.3 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) Peptidase_S41 PF03572.18 KUM66453.1 - 1.1e-08 34.8 0.0 2.9e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase family S41 DUF397 PF04149.12 KUM66453.1 - 0.16 12.0 0.2 1.5 8.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF397) ERCC4 PF02732.15 KUM66454.1 - 3.3e-18 66.4 0.0 2.3e-17 63.7 0.0 2.5 3 0 0 3 3 3 1 ERCC4 domain HHH_5 PF14520.6 KUM66454.1 - 0.0068 17.0 0.0 0.017 15.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Lyase_1 PF00206.20 KUM66456.1 - 2.3e-110 368.9 0.0 3.7e-110 368.2 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KUM66456.1 - 1.8e-20 73.1 0.0 5e-20 71.7 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus Abhydrolase_3 PF07859.13 KUM66457.1 - 5.8e-57 192.9 0.0 8e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KUM66457.1 - 5.8e-05 22.7 0.0 0.0025 17.3 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Aminotran_1_2 PF00155.21 KUM66458.1 - 9e-75 252.1 0.0 1e-74 251.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II fn3_2 PF16893.5 KUM66459.1 - 1e-37 128.2 0.0 1.8e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KUM66459.1 - 5.9e-25 87.0 0.4 1.1e-24 86.2 0.4 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 KUM66459.1 - 4.3e-13 49.0 0.0 7.2e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KUM66459.1 - 8.4e-09 35.7 0.0 1.4e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 KUM66459.1 - 4.3e-05 23.7 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.21 KUM66459.1 - 0.00027 21.2 0.0 0.001 19.3 0.0 2.0 1 1 0 1 1 1 1 Fibronectin type III domain BRCT_2 PF16589.5 KUM66459.1 - 0.0084 16.5 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF2461 PF09365.10 KUM66460.1 - 3.9e-55 187.0 0.0 1.1e-54 185.6 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein (DUF2461) Herpes_UL14 PF03580.14 KUM66460.1 - 0.049 13.9 0.6 0.13 12.5 0.1 1.8 2 0 0 2 2 2 0 Herpesvirus UL14-like protein Zn_clus PF00172.18 KUM66461.1 - 1.1e-08 35.1 6.9 1.6e-08 34.6 6.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ARPC4 PF05856.12 KUM66462.1 - 2.2e-75 251.9 4.1 2.4e-75 251.7 4.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) 4HBT PF03061.22 KUM66464.1 - 2.1e-07 31.2 0.2 3.4e-07 30.5 0.2 1.3 1 0 0 1 1 1 1 Thioesterase superfamily UCH PF00443.29 KUM66465.1 - 7.3e-54 183.0 0.2 9.5e-54 182.6 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KUM66465.1 - 8.2e-11 41.5 0.0 3.1e-10 39.6 0.0 2.1 1 0 0 1 1 1 1 Ubiquitin family UCH_1 PF13423.6 KUM66465.1 - 3.2e-10 40.1 13.0 1.7e-09 37.7 13.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase O-antigen_lig PF13425.6 KUM66465.1 - 6.6 5.4 4.2 9.1 4.9 4.2 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein POP1 PF06978.11 KUM66466.1 - 1.9e-73 246.8 21.8 3.7e-73 245.9 21.8 1.5 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KUM66466.1 - 3.4e-30 104.2 0.4 1.6e-29 102.1 0.4 2.3 1 0 0 1 1 1 1 POPLD (NUC188) domain TRI12 PF06609.13 KUM66467.1 - 1.7e-41 142.3 29.1 2.1e-41 142.1 29.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KUM66467.1 - 3.6e-20 72.2 59.1 4.6e-19 68.6 54.1 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM66467.1 - 2.5e-14 53.0 5.9 2.5e-14 53.0 5.9 3.6 3 1 0 4 4 4 2 Sugar (and other) transporter DUF1690 PF07956.11 KUM66469.1 - 1.5e-38 132.4 4.9 1.6e-18 67.5 0.1 2.0 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Apolipoprotein PF01442.18 KUM66469.1 - 0.14 12.0 9.2 0.41 10.5 3.6 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Matrilin_ccoil PF10393.9 KUM66469.1 - 0.19 11.6 3.8 2.1 8.3 1.1 2.7 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin MRFAP1 PF15155.6 KUM66469.1 - 0.2 12.2 5.2 0.39 11.2 1.0 2.7 2 1 0 2 2 2 0 MORF4 family-associated protein1 PKcGMP_CC PF16808.5 KUM66469.1 - 0.53 10.2 0.0 0.53 10.2 0.0 2.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MFS_1 PF07690.16 KUM66470.1 - 1.5e-34 119.5 29.1 2.5e-34 118.8 29.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KUM66470.1 - 5.1e-06 26.0 6.4 5.1e-06 26.0 6.4 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF3976 PF13121.6 KUM66470.1 - 0.11 12.6 0.3 0.32 11.1 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) ESSS PF10183.9 KUM66470.1 - 0.45 10.8 1.7 10 6.4 0.1 3.4 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DAO PF01266.24 KUM66471.1 - 2.2e-43 149.2 0.1 2.6e-43 149.0 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM66471.1 - 0.00016 21.0 0.0 0.17 11.1 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM66471.1 - 0.00019 21.4 0.1 0.23 11.4 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding GIDA PF01134.22 KUM66471.1 - 0.00052 19.2 0.1 0.012 14.7 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KUM66471.1 - 0.0017 18.5 0.0 0.0045 17.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KUM66471.1 - 0.0056 15.6 0.1 0.12 11.1 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Shikimate_DH PF01488.20 KUM66471.1 - 0.011 15.8 0.0 0.075 13.1 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KUM66471.1 - 0.029 13.4 0.3 0.28 10.2 0.3 2.0 1 1 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KUM66471.1 - 0.044 13.0 0.0 5.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KUM66471.1 - 0.066 12.6 0.0 5.3 6.3 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Fungal_trans_2 PF11951.8 KUM66472.1 - 2.4e-67 227.4 2.5 2.8e-67 227.2 2.5 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.22 KUM66473.1 - 2.3e-77 260.5 0.0 2.9e-77 260.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Promethin PF16015.5 KUM66475.1 - 6.4e-11 42.1 11.5 1.1e-10 41.4 11.5 1.4 1 0 0 1 1 1 1 Promethin GDI PF00996.18 KUM66476.1 - 6.1e-26 90.9 0.0 9.7e-24 83.7 0.0 2.3 1 1 0 1 1 1 1 GDP dissociation inhibitor MFS_1 PF07690.16 KUM66477.1 - 2.1e-14 53.2 41.6 2.7e-12 46.3 43.5 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KUM66477.1 - 6.4e-06 25.0 2.9 6.4e-06 25.0 2.9 3.6 3 1 0 3 3 3 1 MFS/sugar transport protein Pro_isomerase PF00160.21 KUM66478.1 - 6.5e-53 179.2 0.0 7.4e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.13 KUM66479.1 - 1.5e-61 208.5 0.2 4.3e-61 206.9 0.2 1.7 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KUM66479.1 - 0.00026 20.6 3.8 0.00026 20.6 3.8 2.1 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease DUF3216 PF11505.8 KUM66479.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Synaptobrevin PF00957.21 KUM66480.1 - 8.8e-33 112.0 0.8 1e-32 111.8 0.8 1.0 1 0 0 1 1 1 1 Synaptobrevin Prominin PF05478.11 KUM66480.1 - 0.027 12.4 0.1 0.034 12.1 0.1 1.1 1 0 0 1 1 1 0 Prominin OapA_N PF08525.11 KUM66480.1 - 3.1 7.8 6.7 4.6 7.3 6.7 1.2 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif APG6_N PF17675.1 KUM66482.1 - 0.017 15.6 0.6 0.026 15.1 0.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region FSH1 PF03959.13 KUM66483.1 - 7.1e-25 87.9 0.0 8.1e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KUM66483.1 - 0.0024 18.5 0.0 0.0027 18.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KUM66483.1 - 0.029 14.2 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF3089 PF11288.8 KUM66483.1 - 0.073 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) adh_short PF00106.25 KUM66484.1 - 2.5e-24 85.8 0.0 2.3e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM66484.1 - 6e-10 39.1 0.0 1.6e-08 34.4 0.0 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM66484.1 - 2.3e-08 34.1 0.0 4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KUM66484.1 - 0.0033 16.6 0.0 0.0047 16.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KUM66484.1 - 0.079 12.4 0.0 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KUM66484.1 - 0.14 12.2 0.0 0.58 10.2 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApoC-I PF04691.12 KUM66484.1 - 0.44 10.5 1.4 9.2 6.3 0.4 2.4 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) Epimerase PF01370.21 KUM66485.1 - 2.6e-23 82.7 0.0 6.3e-23 81.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM66485.1 - 1.9e-11 43.9 0.0 6.4e-11 42.2 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KUM66485.1 - 2e-09 36.9 0.0 4.7e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KUM66485.1 - 3.2e-08 33.7 0.0 9.4e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KUM66485.1 - 2.5e-07 30.1 0.0 6.6e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 KUM66485.1 - 1.7e-05 24.0 0.0 2.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KUM66485.1 - 0.00025 20.3 0.0 0.0024 17.1 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein PspC PF04024.12 KUM66485.1 - 0.09 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 PspC domain NAC PF01849.18 KUM66486.1 - 2.4e-24 85.0 0.1 4e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 NAC domain MAGI_u1 PF16663.5 KUM66486.1 - 0.025 14.6 0.1 0.052 13.6 0.1 1.5 1 0 0 1 1 1 0 Unstructured region on MAGI Med17 PF10156.9 KUM66486.1 - 0.045 12.5 0.4 0.045 12.5 0.4 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Nup35_RRM PF05172.13 KUM66487.1 - 0.0031 17.4 0.0 0.012 15.6 0.0 1.9 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF1233 PF06806.12 KUM66487.1 - 0.14 11.8 0.1 0.36 10.5 0.1 1.7 1 0 0 1 1 1 0 Putative excisionase (DUF1233) His_Phos_2 PF00328.22 KUM66488.1 - 3.7e-33 115.4 0.0 4.9e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Hydantoinase_B PF02538.14 KUM66489.1 - 3.7e-198 659.1 0.3 5.2e-198 658.6 0.3 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KUM66489.1 - 2.5e-106 355.2 0.4 1.2e-105 352.9 0.1 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KUM66489.1 - 7.1e-61 205.0 2.2 2.3e-59 200.1 0.1 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.9 KUM66489.1 - 0.021 14.5 0.0 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature WH1 PF00568.23 KUM66490.1 - 3.2e-29 101.1 0.0 5.1e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 WH1 domain DCP1 PF06058.13 KUM66490.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Dcp1-like decapping family DUF1348 PF07080.11 KUM66491.1 - 3.7e-57 191.8 2.0 4.7e-57 191.5 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KUM66491.1 - 6e-05 23.6 1.3 0.0001 22.9 1.3 1.5 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KUM66491.1 - 0.00041 20.7 0.2 0.00065 20.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Pkinase PF00069.25 KUM66492.1 - 1.1e-65 221.7 0.0 1.5e-64 217.9 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 KUM66492.1 - 2.4e-38 130.5 0.7 5.2e-38 129.4 0.7 1.6 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 KUM66492.1 - 6.5e-35 120.7 0.0 3e-33 115.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KUM66492.1 - 0.00013 21.0 0.0 0.0003 19.9 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KUM66492.1 - 0.00029 20.9 0.2 0.0096 15.9 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KUM66492.1 - 0.00052 19.4 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KUM66492.1 - 0.0037 16.6 0.0 0.0072 15.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 KUM66492.1 - 0.018 14.6 0.0 0.049 13.2 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF844 PF05815.11 KUM66492.1 - 0.085 12.1 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) P5CR_dimer PF14748.6 KUM66493.1 - 1.1e-30 105.9 3.0 1.1e-30 105.9 3.0 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KUM66493.1 - 4.6e-13 49.6 0.3 1.3e-12 48.1 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent BacteriocIIc_cy PF12173.8 KUM66493.1 - 0.41 10.9 3.8 1.6 9.0 0.6 2.3 2 0 0 2 2 2 0 Bacteriocin class IIc cyclic gassericin A-like DAO PF01266.24 KUM66494.1 - 1.5e-08 34.7 0.0 1.2e-05 25.0 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KUM66494.1 - 0.00036 20.7 0.1 0.00067 19.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KUM66494.1 - 0.0015 17.8 0.0 0.002 17.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM66494.1 - 0.0052 15.9 0.1 0.0076 15.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KUM66494.1 - 0.016 15.8 0.0 0.029 14.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM66494.1 - 0.088 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 KUM66494.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KUM66494.1 - 0.11 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KUM66494.1 - 0.13 11.5 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.21 KUM66494.1 - 0.19 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 ThiF family Redoxin PF08534.10 KUM66495.1 - 1.1e-34 119.3 0.0 1.2e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KUM66495.1 - 3.6e-13 49.5 0.0 4.5e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family MFS_1 PF07690.16 KUM66496.1 - 4.3e-45 154.2 56.8 1.9e-44 152.1 52.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM66496.1 - 2e-15 56.6 14.2 2e-15 56.6 14.2 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KUM66496.1 - 3.3e-15 55.5 22.7 3.3e-15 55.5 22.7 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UQ_con PF00179.26 KUM66497.1 - 5.1e-47 159.0 0.0 5.8e-47 158.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KUM66497.1 - 0.00023 20.8 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KUM66497.1 - 0.015 15.1 0.0 0.03 14.2 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 KUM66497.1 - 0.14 12.4 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.32 KUM66498.1 - 1.3e-06 29.0 21.2 0.0049 17.7 0.1 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KUM66498.1 - 2.6e-06 27.0 17.0 2.6e-06 27.0 17.0 2.6 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_14 PF17978.1 KUM66498.1 - 0.076 13.5 3.8 0.15 12.5 3.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KUM66498.1 - 8.6 6.3 10.3 0.37 10.7 4.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M36 PF02128.15 KUM66499.1 - 0.093 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) SH3_1 PF00018.28 KUM66500.1 - 0.043 13.4 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 SH3 domain CcmD PF04995.14 KUM66500.1 - 0.16 12.0 1.3 0.3 11.2 1.3 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) NAD_binding_6 PF08030.12 KUM66501.1 - 2.9e-22 79.5 0.0 5.1e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KUM66501.1 - 1.2e-17 64.2 10.8 1.2e-17 64.2 10.8 3.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KUM66501.1 - 6.4e-14 52.0 0.0 1.9e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KUM66501.1 - 0.00066 20.3 0.0 0.18 12.4 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain RNase_PH PF01138.21 KUM66502.1 - 2.7e-13 50.6 0.2 1.2e-12 48.4 0.2 2.0 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 p450 PF00067.22 KUM66503.1 - 1.1e-63 215.6 0.0 1.5e-63 215.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sdh_cyt PF01127.22 KUM66503.1 - 0.11 12.5 0.5 0.24 11.4 0.5 1.5 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit zf-C2HC5 PF06221.13 KUM66504.1 - 1.1e-21 76.5 4.6 1.7e-21 75.9 4.6 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Sgf11 PF08209.11 KUM66505.1 - 1.5e-06 27.6 0.8 1.5e-06 27.6 0.8 1.9 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 KUM66505.1 - 0.064 13.2 0.9 0.12 12.3 0.9 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Actin_micro PF17003.5 KUM66505.1 - 0.11 11.7 0.2 0.19 10.9 0.2 1.4 2 0 0 2 2 2 0 Putative actin-like family Neuromodulin_N PF10580.9 KUM66505.1 - 0.22 11.4 3.3 1 9.2 0.2 2.3 2 0 0 2 2 2 0 Gap junction protein N-terminal region zf-C2H2_4 PF13894.6 KUM66505.1 - 1.3 10.0 3.9 1 10.4 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Acetyltransf_1 PF00583.25 KUM66506.1 - 0.016 15.4 0.0 0.082 13.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Hexokinase_2 PF03727.16 KUM66507.1 - 4.3e-79 265.3 0.0 5.5e-79 265.0 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KUM66507.1 - 7e-70 235.0 0.0 1.1e-69 234.3 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Aldo_ket_red PF00248.21 KUM66508.1 - 4.3e-71 239.5 0.0 5.3e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 KUM66509.1 - 5.8e-44 150.5 51.1 5.8e-44 150.5 51.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily EbsA PF17255.2 KUM66509.1 - 0.73 10.2 3.5 23 5.3 0.0 2.7 2 0 0 2 2 2 0 EbsA-like protein Mpv17_PMP22 PF04117.12 KUM66510.1 - 4e-09 36.6 0.1 8.9e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Zn_clus PF00172.18 KUM66511.1 - 1.8e-05 24.8 16.2 1.8e-05 24.8 16.2 2.2 2 1 1 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Chitin_synth_1 PF01644.17 KUM66512.1 - 4.5e-69 231.6 0.0 6.3e-69 231.1 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KUM66512.1 - 4e-27 95.0 0.1 5.8e-21 74.7 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 KUM66512.1 - 6.5e-27 93.3 0.1 2.1e-26 91.7 0.1 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 KUM66512.1 - 1.7e-09 37.9 0.0 1.7e-09 37.9 0.0 2.7 3 1 0 3 3 3 1 Glycosyl transferase family group 2 RAP1 PF07218.11 KUM66513.1 - 0.092 11.0 4.1 0.11 10.8 4.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sporozoite_P67 PF05642.11 KUM66513.1 - 0.36 8.9 6.6 0.34 8.9 6.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Alpha_GJ PF03229.13 KUM66513.1 - 0.51 10.9 9.5 0.085 13.4 3.1 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J NAT PF04768.13 KUM66514.1 - 1.7e-56 190.6 0.3 3.6e-56 189.5 0.1 1.7 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 KUM66514.1 - 1.3e-30 106.3 0.0 5.1e-30 104.4 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KUM66514.1 - 4.8e-29 101.7 0.0 9.8e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.20 KUM66514.1 - 0.043 13.9 0.0 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Rad21_Rec8_N PF04825.13 KUM66515.1 - 1.4e-26 92.8 0.0 3.2e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KUM66515.1 - 0.00059 19.1 0.0 0.0018 17.6 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF3237 PF11578.8 KUM66516.1 - 7.2e-35 120.0 0.0 1.1e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.15 KUM66516.1 - 0.0007 19.6 7.0 0.081 13.0 0.3 2.8 3 0 0 3 3 3 2 BED zinc finger zf-C2H2_2 PF12756.7 KUM66516.1 - 0.031 14.6 4.1 2.9 8.3 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS91 PF14319.6 KUM66516.1 - 0.65 10.1 11.5 0.8 9.8 2.2 2.2 2 0 0 2 2 2 0 Transposase zinc-binding domain PyrI_C PF02748.15 KUM66516.1 - 1 9.3 6.0 7.4 6.6 0.5 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain TPR_1 PF00515.28 KUM66518.1 - 4.5e-37 124.4 24.8 0.0013 18.5 0.1 11.2 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KUM66518.1 - 3.3e-34 114.2 26.3 7.1e-05 22.6 0.1 11.0 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.6 KUM66518.1 - 6.9e-23 81.0 15.1 1e-05 26.1 0.0 6.9 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 KUM66518.1 - 1.6e-18 65.3 20.6 0.0098 16.0 0.1 9.5 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 KUM66518.1 - 4.1e-18 64.8 23.5 0.00011 21.8 0.0 8.8 6 1 2 8 8 8 6 TPR repeat TPR_17 PF13431.6 KUM66518.1 - 6.6e-16 57.5 4.5 0.28 11.6 0.0 8.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 KUM66518.1 - 5.4e-14 52.1 10.7 3e-05 24.1 0.1 5.5 4 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KUM66518.1 - 7.9e-12 45.3 35.5 0.00088 19.5 2.4 8.8 4 3 4 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 KUM66518.1 - 1.3e-11 44.2 10.6 0.023 15.5 0.0 7.5 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KUM66518.1 - 3.2e-10 40.4 23.0 5.7e-05 23.6 0.8 7.0 5 1 4 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KUM66518.1 - 1.2e-09 37.6 18.1 0.025 14.6 0.1 8.5 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 KUM66518.1 - 1.1e-05 25.1 18.9 0.23 11.4 0.4 8.4 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KUM66518.1 - 1.8e-05 24.3 1.8 1.8e-05 24.3 1.8 2.3 2 1 0 2 2 2 1 MalT-like TPR region SHNi-TPR PF10516.9 KUM66518.1 - 2.5e-05 23.6 7.6 0.12 11.8 0.0 5.9 5 0 0 5 5 5 1 SHNi-TPR ANAPC3 PF12895.7 KUM66518.1 - 5.3e-05 23.4 15.1 0.11 12.7 0.0 5.1 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KUM66518.1 - 0.004 17.7 21.8 6.6 7.6 0.0 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat MAS20 PF02064.15 KUM66518.1 - 0.01 16.0 11.1 0.39 10.8 0.2 4.4 4 2 1 5 5 5 0 MAS20 protein import receptor OAD_gamma PF04277.13 KUM66518.1 - 0.093 13.3 0.6 0.26 11.9 0.0 2.1 2 0 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain HemY_N PF07219.13 KUM66518.1 - 0.33 11.2 7.1 26 5.0 0.9 4.3 3 1 1 4 4 4 0 HemY protein N-terminus Sel1 PF08238.12 KUM66518.1 - 0.38 11.5 7.3 0.89 10.3 0.2 4.4 4 0 0 4 4 3 0 Sel1 repeat ANAPC5 PF12862.7 KUM66518.1 - 1.8 8.7 12.6 17 5.6 0.0 4.4 4 2 1 5 5 4 0 Anaphase-promoting complex subunit 5 MIT PF04212.18 KUM66518.1 - 2.9 8.0 19.1 9.7 6.3 0.1 6.7 7 1 0 7 7 6 0 MIT (microtubule interacting and transport) domain FHA PF00498.26 KUM66519.1 - 1.7e-13 50.7 0.0 3.2e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain Ost5 PF05251.12 KUM66519.1 - 0.13 12.6 0.2 0.25 11.6 0.2 1.4 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 NOA36 PF06524.12 KUM66519.1 - 0.32 10.3 13.0 0.55 9.5 13.0 1.2 1 0 0 1 1 1 0 NOA36 protein Aldo_ket_red PF00248.21 KUM66520.1 - 4.4e-73 246.0 0.0 4.8e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_3 PF07859.13 KUM66521.1 - 5.7e-16 59.0 0.0 8e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KUM66521.1 - 6.2e-06 25.8 0.0 0.016 14.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KUM66521.1 - 4.9e-05 22.7 0.0 0.00017 20.9 0.0 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 COesterase PF00135.28 KUM66521.1 - 0.00017 20.6 0.0 0.00033 19.7 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family AXE1 PF05448.12 KUM66521.1 - 0.0046 15.7 0.0 0.35 9.5 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KUM66521.1 - 0.026 14.2 0.1 0.069 12.8 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KUM66521.1 - 0.043 13.5 0.0 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 Putative esterase Esterase_phd PF10503.9 KUM66521.1 - 0.073 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Pneumo_ncap PF03246.13 KUM66522.1 - 0.098 11.4 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Pneumovirus nucleocapsid protein DUF3500 PF12006.8 KUM66523.1 - 2.3e-109 365.5 0.0 2.7e-109 365.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) SPC12 PF06645.13 KUM66524.1 - 0.2 11.7 7.6 0.52 10.4 0.1 3.1 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) RRM_1 PF00076.22 KUM66525.1 - 4.4e-53 177.0 0.1 8.3e-20 70.4 0.1 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KUM66525.1 - 3.9e-32 109.9 0.0 2.7e-27 94.4 0.0 4.3 4 1 0 4 4 4 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KUM66525.1 - 0.00012 22.0 0.0 0.46 10.5 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif DUF4651 PF15513.6 KUM66525.1 - 0.05 13.4 0.1 3.6 7.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) RRM_7 PF16367.5 KUM66525.1 - 0.064 13.4 0.1 3.7 7.7 0.0 3.7 4 0 0 4 4 4 0 RNA recognition motif Lsm_interact PF05391.11 KUM66525.1 - 0.11 12.0 1.8 0.3 10.6 1.8 1.8 1 0 0 1 1 1 0 Lsm interaction motif Phage_Mu_F PF04233.14 KUM66525.1 - 0.16 12.7 3.5 0.58 10.9 3.5 1.9 1 0 0 1 1 1 0 Phage Mu protein F like protein TPR_14 PF13428.6 KUM66525.1 - 0.19 12.6 2.5 3.9 8.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Spt20 PF12090.8 KUM66525.1 - 0.43 10.2 9.9 0.98 9.0 9.9 1.5 1 0 0 1 1 1 0 Spt20 family tRNA-synt_1b PF00579.25 KUM66526.1 - 2.7e-17 63.0 0.1 1.1e-16 61.1 0.1 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Aminotran_4 PF01063.19 KUM66527.1 - 2.6e-38 132.1 0.0 3.1e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV Amino_oxidase PF01593.24 KUM66528.1 - 1.9e-53 182.4 0.0 2.2e-53 182.2 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KUM66528.1 - 2.6e-12 46.8 0.3 5.1e-12 45.9 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM66528.1 - 7.5e-09 35.6 1.5 1.9e-07 31.0 1.5 2.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KUM66528.1 - 7.5e-07 28.8 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KUM66528.1 - 1.4e-06 27.7 0.5 2.2e-06 27.0 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KUM66528.1 - 3e-06 26.6 0.4 5.7e-06 25.7 0.4 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KUM66528.1 - 2.5e-05 23.7 0.0 6.3e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KUM66528.1 - 0.00022 20.6 0.7 0.00036 19.9 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KUM66528.1 - 0.00027 20.2 0.0 0.00039 19.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KUM66528.1 - 0.00038 19.3 0.0 0.00098 17.9 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KUM66528.1 - 0.0014 17.7 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 KUM66528.1 - 0.0016 18.9 0.1 0.0057 17.2 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KUM66528.1 - 0.024 14.7 0.2 2.9 7.8 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding YIF1 PF03878.15 KUM66528.1 - 0.024 14.2 0.2 0.051 13.1 0.2 1.4 1 0 0 1 1 1 0 YIF1 Pyr_redox_3 PF13738.6 KUM66528.1 - 0.042 13.1 0.0 4.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease_2 PF13520.6 KUM66529.1 - 5.9e-19 68.2 11.3 6.5e-19 68.1 11.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM66529.1 - 2.6e-10 39.5 10.5 2.8e-10 39.4 10.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2861 PF11060.8 KUM66530.1 - 0.12 12.0 0.1 0.31 10.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2861) Metallophos PF00149.28 KUM66531.1 - 8.6e-09 36.2 2.8 8.6e-09 36.2 2.8 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Fungal_trans_2 PF11951.8 KUM66532.1 - 2.3e-11 43.1 0.4 2.6e-11 43.0 0.4 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nuc_deoxyri_tr2 PF15891.5 KUM66533.1 - 0.14 12.5 0.2 2.6 8.4 0.1 2.2 1 1 1 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like Maf1 PF09174.10 KUM66534.1 - 3.5e-60 203.1 0.0 4.7e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator Filament PF00038.21 KUM66535.1 - 9.6e-07 28.7 19.8 9.6e-07 28.7 19.8 3.8 1 1 2 3 3 3 1 Intermediate filament protein ATG16 PF08614.11 KUM66535.1 - 0.0098 16.1 35.8 0.0098 16.1 35.8 5.4 2 2 2 4 4 4 2 Autophagy protein 16 (ATG16) T2SSF PF00482.23 KUM66535.1 - 1.6 8.7 7.8 4.8 7.1 0.1 3.4 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F ORF11CD3 PF10549.9 KUM66535.1 - 3.9 7.7 8.6 0.17 12.0 0.4 2.9 3 0 0 3 3 3 0 ORF11CD3 domain LCIB_C_CA PF18599.1 KUM66535.1 - 4.2 6.6 5.9 1.8 7.8 2.8 2.0 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases APG17 PF04108.12 KUM66535.1 - 4.7 6.2 33.0 3.4 6.7 6.5 2.6 1 1 1 2 2 2 0 Autophagy protein Apg17 HAP1_N PF04849.13 KUM66535.1 - 4.8 6.3 53.6 0.17 11.1 18.8 3.9 1 1 2 3 3 3 0 HAP1 N-terminal conserved region MARVEL PF01284.23 KUM66536.1 - 1.3e-29 103.0 12.6 1.6e-29 102.7 12.6 1.0 1 0 0 1 1 1 1 Membrane-associating domain Clat_adaptor_s PF01217.20 KUM66537.1 - 1.8e-53 180.3 1.4 2.2e-53 180.0 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Fungal_trans_2 PF11951.8 KUM66537.1 - 0.034 12.9 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain ABC2_membrane PF01061.24 KUM66539.1 - 4.7e-39 134.0 27.9 4.7e-39 134.0 27.9 1.8 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 KUM66539.1 - 3.1e-05 23.8 0.2 3.1e-05 23.8 0.2 3.1 2 1 1 3 3 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 KUM66539.1 - 6 5.9 27.2 16 4.5 27.0 2.0 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane PF01061.24 KUM66540.1 - 4.7e-46 156.8 20.2 4.7e-46 156.8 20.2 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KUM66540.1 - 3.6e-39 134.4 0.0 4.7e-19 69.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KUM66540.1 - 1.8e-29 101.5 0.1 1.8e-29 101.5 0.1 2.4 3 0 0 3 3 2 1 CDR ABC transporter ABC_trans_N PF14510.6 KUM66540.1 - 6.7e-13 49.1 0.1 1.6e-12 47.9 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KUM66540.1 - 4.1e-08 32.7 11.2 4.1e-08 32.7 11.2 2.0 1 1 0 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.6 KUM66540.1 - 4.7e-08 32.8 0.0 1e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KUM66540.1 - 4.8e-06 26.6 0.1 0.0036 17.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KUM66540.1 - 4e-05 24.1 0.0 0.0063 16.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KUM66540.1 - 7.5e-05 22.9 0.1 0.0036 17.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KUM66540.1 - 0.00021 21.0 1.3 0.033 13.9 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KUM66540.1 - 0.00043 20.8 0.0 0.0045 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KUM66540.1 - 0.0017 18.6 0.1 0.93 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KUM66540.1 - 0.0026 17.4 0.7 0.032 13.8 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KUM66540.1 - 0.0033 17.5 0.0 2 8.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 KUM66540.1 - 0.026 14.4 0.1 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_30 PF13604.6 KUM66540.1 - 0.032 14.0 1.6 2.2 7.9 0.4 2.9 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KUM66540.1 - 0.038 13.7 0.0 13 5.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KUM66540.1 - 0.051 13.5 0.1 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 KUM66540.1 - 0.067 13.6 0.3 0.51 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.7 KUM66540.1 - 0.12 11.6 12.0 0.0098 15.2 6.3 2.0 2 1 0 2 2 2 0 ABC-2 family transporter protein PufQ PF05398.11 KUM66540.1 - 0.3 11.3 2.9 11 6.3 0.4 2.6 2 0 0 2 2 2 0 PufQ cytochrome subunit DUF1761 PF08570.10 KUM66540.1 - 2.8 8.2 17.2 0.61 10.3 4.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1761) MRC1 PF09444.10 KUM66541.1 - 2.7e-39 135.0 22.9 2.7e-39 135.0 22.9 7.4 7 3 1 8 8 8 1 MRC1-like domain KR PF08659.10 KUM66541.1 - 0.0071 16.3 0.7 0.017 15.0 0.7 1.6 1 0 0 1 1 1 1 KR domain Plus-3 PF03126.18 KUM66542.1 - 6.3e-31 107.1 0.0 1.7e-29 102.5 0.0 2.6 2 0 0 2 2 2 1 Plus-3 domain Hydrolase_like PF13242.6 KUM66543.1 - 0.00019 21.4 0.0 0.0018 18.3 0.0 2.5 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KUM66543.1 - 0.032 14.5 0.0 0.42 10.9 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase mRNA_cap_enzyme PF01331.19 KUM66543.1 - 0.076 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain HAD_2 PF13419.6 KUM66543.1 - 0.16 12.0 0.0 0.49 10.5 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase 3HCDH_N PF02737.18 KUM66544.1 - 6.3e-28 97.9 0.0 9.4e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KUM66544.1 - 2.6e-17 63.2 0.0 1.1e-16 61.2 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 KUM66544.1 - 0.01 15.8 0.1 0.026 14.5 0.1 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 KUM66544.1 - 0.011 15.9 0.0 0.035 14.4 0.0 1.9 1 1 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KUM66544.1 - 0.028 13.7 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KUM66544.1 - 0.065 12.9 0.0 0.29 10.8 0.0 2.0 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KUM66544.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KUM66544.1 - 0.14 12.8 0.0 0.34 11.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 KUM66544.1 - 0.19 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Chitin_synth_1 PF01644.17 KUM66545.1 - 1.1e-75 253.1 0.0 1.6e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KUM66545.1 - 6.3e-28 96.5 0.0 1.2e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KUM66545.1 - 1.4e-21 76.7 7.2 5.5e-19 68.2 0.0 2.2 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KUM66545.1 - 1e-06 28.8 3.3 1e-06 28.8 3.3 2.7 3 1 0 3 3 3 1 Glycosyl transferase family group 2 TMEM234 PF10639.9 KUM66546.1 - 1.6e-33 115.2 0.1 8.2e-26 90.3 0.1 2.1 2 0 0 2 2 2 2 Putative transmembrane family 234 EamA PF00892.20 KUM66546.1 - 0.029 14.5 9.0 1.1 9.4 5.1 2.2 2 0 0 2 2 2 0 EamA-like transporter family DUF1211 PF06736.11 KUM66546.1 - 0.061 13.8 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) COQ7 PF03232.13 KUM66547.1 - 8.6e-68 227.5 1.1 9.6e-68 227.3 1.1 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KUM66547.1 - 4.4e-07 30.4 2.9 2.7e-06 27.8 0.1 2.1 1 1 1 2 2 2 1 Rubrerythrin UPF0184 PF03670.13 KUM66547.1 - 0.068 13.6 0.5 0.1 13.0 0.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Crr6 PF08847.11 KUM66547.1 - 0.069 12.8 0.1 1.1 8.9 0.0 2.1 1 1 1 2 2 2 0 Chlororespiratory reduction 6 SPT2 PF08243.11 KUM66547.1 - 0.31 11.6 4.7 0.45 11.1 4.7 1.1 1 0 0 1 1 1 0 SPT2 chromatin protein LMWPc PF01451.21 KUM66548.1 - 2.4e-21 76.6 0.0 5.5e-15 56.0 0.0 2.1 2 0 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase Spidroin_N PF16763.5 KUM66548.1 - 0.11 12.5 0.1 0.24 11.4 0.0 1.5 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term Pkinase PF00069.25 KUM66549.1 - 1.8e-54 184.9 0.0 2.4e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM66549.1 - 1.5e-19 70.3 0.1 2.9e-19 69.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KUM66549.1 - 0.18 11.7 0.0 0.56 10.1 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family COPIIcoated_ERV PF07970.12 KUM66550.1 - 1.2e-35 123.4 0.0 2e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KUM66550.1 - 7e-25 87.2 0.0 1.8e-24 85.9 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) C2 PF00168.30 KUM66551.1 - 1.7e-15 57.2 0.0 3.1e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain Caldesmon PF02029.15 KUM66551.1 - 5.6 5.6 30.4 9.4 4.9 30.4 1.3 1 0 0 1 1 1 0 Caldesmon Pkinase PF00069.25 KUM66553.1 - 1.7e-72 244.0 0.0 2.3e-72 243.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM66553.1 - 2.7e-35 121.9 0.0 3.8e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KUM66553.1 - 1.3e-18 67.6 0.1 5.1e-12 46.3 0.0 2.5 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KUM66553.1 - 2e-13 50.2 0.0 4.4e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KUM66553.1 - 2.1e-05 24.0 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KUM66553.1 - 0.00037 20.1 0.1 0.00092 18.8 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KUM66553.1 - 0.0094 14.9 0.1 0.015 14.3 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KUM66553.1 - 0.023 14.1 0.1 0.053 12.9 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 KUM66553.1 - 0.11 11.3 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 KUM66553.1 - 0.15 11.9 0.1 0.15 11.9 0.1 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KUM66553.1 - 0.16 10.9 0.3 0.26 10.2 0.3 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MFS_MOT1 PF16983.5 KUM66555.1 - 2.2e-63 211.6 32.6 1.4e-34 118.9 7.6 3.2 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 KUM66555.1 - 0.061 12.1 24.5 0.0093 14.8 5.4 2.6 1 1 1 2 2 2 0 Sulfate permease family PhyH PF05721.13 KUM66557.1 - 1.1e-44 153.3 0.0 1.3e-44 153.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UTP15_C PF09384.10 KUM66558.1 - 2.7e-52 176.4 2.1 2.7e-52 176.4 2.1 1.7 2 0 0 2 2 2 1 UTP15 C terminal WD40 PF00400.32 KUM66558.1 - 4.1e-19 68.6 1.1 0.00037 21.2 0.2 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM66558.1 - 8.6e-08 32.4 0.2 0.0056 16.9 0.0 3.9 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KUM66558.1 - 0.00023 20.8 0.4 0.014 14.9 0.0 2.6 3 0 0 3 3 3 1 PQQ-like domain RAB3GAP2_N PF14655.6 KUM66558.1 - 0.0023 17.3 0.2 0.37 10.0 0.2 2.4 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus CPSF_A PF03178.15 KUM66558.1 - 0.0042 16.5 0.0 0.02 14.2 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region His_Phos_1 PF00300.22 KUM66559.1 - 3.3e-14 53.0 0.8 2.5e-13 50.2 0.8 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_L22 PF00237.19 KUM66560.1 - 1e-30 106.0 0.1 2e-30 105.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Mito_carr PF00153.27 KUM66561.1 - 1.4e-55 185.2 0.8 2.4e-19 69.0 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ASC PF00858.24 KUM66561.1 - 0.61 9.0 1.3 0.86 8.5 1.3 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel CCDC14 PF15254.6 KUM66563.1 - 0.45 9.1 4.3 0.66 8.6 4.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 Nop16 PF09420.10 KUM66565.1 - 4e-64 216.5 8.8 4.9e-64 216.2 8.8 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Pex24p PF06398.11 KUM66566.1 - 1.1e-89 300.9 0.0 1.4e-89 300.6 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.12 KUM66566.1 - 0.06 12.7 0.5 0.11 11.9 0.5 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF3292 PF11696.8 KUM66566.1 - 0.18 10.1 3.8 0.5 8.7 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3292) Anp1 PF03452.14 KUM66567.1 - 2e-107 358.5 0.0 2.4e-107 358.3 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KUM66567.1 - 0.0061 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Zip PF02535.22 KUM66568.1 - 2.3e-58 198.0 7.3 4.5e-58 197.1 7.3 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter DUF456 PF04306.13 KUM66568.1 - 3.3 8.0 15.7 18 5.6 10.2 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF456) E1-E2_ATPase PF00122.20 KUM66569.1 - 2.2e-40 138.1 10.4 7.8e-31 107.0 0.0 3.7 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KUM66569.1 - 3e-27 95.5 2.7 3e-27 95.5 2.7 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KUM66569.1 - 6.4e-18 65.8 0.0 7.2e-17 62.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KUM66569.1 - 4.4e-16 58.3 0.0 1.2e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KUM66569.1 - 9.7e-13 48.0 0.0 1.8e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KUM66569.1 - 2.9e-06 27.2 2.8 6.6e-06 26.0 1.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KUM66569.1 - 0.017 15.0 1.1 0.048 13.5 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) PRELI PF04707.14 KUM66570.1 - 1.5e-25 89.9 0.0 1.7e-21 76.6 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family zf-MYND PF01753.18 KUM66571.1 - 5e-09 36.1 8.6 8.9e-09 35.3 8.6 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KUM66571.1 - 0.14 12.3 4.6 0.3 11.2 4.6 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 KUM66571.1 - 0.29 11.0 3.2 0.56 10.1 3.2 1.5 1 0 0 1 1 1 0 HIT zinc finger GFA PF04828.14 KUM66572.1 - 7.7e-15 55.0 1.9 1.5e-14 54.1 1.9 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 KUM66572.1 - 0.33 11.1 6.1 2.3 8.5 6.1 2.2 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DUF35_N PF12172.8 KUM66572.1 - 5 7.1 8.9 11 6.1 0.3 3.2 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) adh_short PF00106.25 KUM66573.1 - 1.3e-54 184.6 0.6 1.7e-54 184.3 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM66573.1 - 1.2e-52 178.8 1.3 1.5e-52 178.5 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM66573.1 - 6.7e-12 45.7 0.1 9.4e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KUM66573.1 - 2.2e-05 24.4 0.1 3.8e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KUM66573.1 - 0.0001 21.5 0.1 0.00015 21.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KUM66573.1 - 0.00021 20.8 0.1 0.00034 20.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KUM66573.1 - 0.00022 20.3 0.1 0.00029 19.9 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 KUM66573.1 - 0.00037 21.0 0.0 0.00071 20.1 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 KUM66573.1 - 0.0033 16.6 0.0 0.0047 16.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.18 KUM66573.1 - 0.005 17.1 0.0 0.0091 16.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 KUM66573.1 - 0.0071 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Methyltransf_12 PF08242.12 KUM66573.1 - 0.014 16.2 0.0 0.023 15.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_7 PF13241.6 KUM66573.1 - 0.021 15.2 0.0 0.033 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Methyltransf_25 PF13649.6 KUM66573.1 - 0.027 15.2 0.0 0.053 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.21 KUM66573.1 - 0.032 14.3 0.2 0.11 12.6 0.2 1.8 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.19 KUM66573.1 - 0.038 13.3 0.1 0.082 12.2 0.0 1.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3783 PF12646.7 KUM66573.1 - 0.094 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) NAD_binding_10 PF13460.6 KUM66573.1 - 0.094 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Staph_opine_DH PF10100.9 KUM66573.1 - 0.19 10.4 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase PSP1 PF04468.12 KUM66574.1 - 0.017 15.4 0.6 0.024 14.9 0.6 1.2 1 0 0 1 1 1 0 PSP1 C-terminal conserved region Erp_C PF06780.11 KUM66574.1 - 0.04 13.9 1.7 0.065 13.3 1.7 1.3 1 0 0 1 1 1 0 Erp protein C-terminus GAS PF13851.6 KUM66574.1 - 0.14 11.4 8.4 0.2 11.0 8.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.19 KUM66574.1 - 1.6 6.5 4.8 1.9 6.3 4.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAF_2 PF13185.6 KUM66575.1 - 4.5e-12 46.4 0.0 5.9e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KUM66575.1 - 1.9e-08 35.0 0.0 2.5e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KUM66575.1 - 0.0027 18.1 0.0 0.0053 17.1 0.0 1.4 1 0 0 1 1 1 1 GAF domain Protoglobin PF11563.8 KUM66575.1 - 0.024 14.6 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Protoglobin SpoVT_C PF15714.5 KUM66575.1 - 0.061 13.4 0.0 0.084 12.9 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor NAD_kinase PF01513.21 KUM66576.1 - 4.1e-79 265.8 0.0 6.2e-79 265.2 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DUF3638 PF12340.8 KUM66579.1 - 3.9e-21 75.4 0.0 5e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) G-7-MTase PF12803.7 KUM66580.1 - 0.0071 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 mRNA (guanine-7-)methyltransferase (G-7-MTase) RmuC PF02646.16 KUM66582.1 - 0.062 12.4 0.1 0.072 12.2 0.1 1.0 1 0 0 1 1 1 0 RmuC family FAD_binding_3 PF01494.19 KUM66583.1 - 5.3e-19 68.7 0.1 1.8e-18 66.9 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KUM66583.1 - 9.5e-07 29.0 0.4 2.7e-06 27.5 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM66583.1 - 0.0013 18.4 0.5 0.0053 16.4 0.2 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM66583.1 - 0.0095 15.2 0.4 0.025 13.8 0.4 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM66583.1 - 0.011 14.9 1.2 0.025 13.7 0.5 1.9 3 0 0 3 3 3 0 FAD binding domain Trp_halogenase PF04820.14 KUM66583.1 - 0.092 11.6 0.4 0.15 10.9 0.4 1.3 1 0 0 1 1 1 0 Tryptophan halogenase AbiEii PF08843.11 KUM66584.1 - 0.015 15.3 0.0 0.62 10.0 0.0 2.2 1 1 1 2 2 2 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system WhiA_N PF10298.9 KUM66585.1 - 0.05 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain DUF1153 PF06627.11 KUM66585.1 - 0.051 13.7 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1153) GMC_oxred_N PF00732.19 KUM66586.1 - 2.9e-26 92.6 0.0 4.5e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM66586.1 - 1.3e-19 71.1 0.7 2.7e-19 70.1 0.7 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KUM66586.1 - 4e-07 29.9 3.0 9.2e-06 25.5 3.0 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KUM66586.1 - 1.8e-06 27.3 1.4 0.0096 15.0 0.5 2.4 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KUM66586.1 - 2.2e-06 26.6 0.3 3.7e-05 22.6 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KUM66586.1 - 8.6e-06 26.2 0.2 0.026 15.1 0.2 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KUM66586.1 - 1.5e-05 24.6 0.2 0.00043 19.7 0.2 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM66586.1 - 8.3e-05 22.0 0.2 0.0023 17.2 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM66586.1 - 0.00022 20.6 2.6 0.021 14.1 0.8 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM66586.1 - 0.00035 20.7 0.0 0.0012 19.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KUM66586.1 - 0.001 18.4 0.0 0.0029 16.9 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KUM66586.1 - 0.0021 17.3 0.1 0.0044 16.3 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KUM66586.1 - 0.0088 15.1 0.1 0.017 14.2 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KUM66586.1 - 0.011 14.9 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyco_hydro_47 PF01532.20 KUM66588.1 - 4.3e-37 128.1 0.0 5.4e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.20 KUM66589.1 - 1.1e-80 271.8 0.0 1.2e-80 271.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Haem_degrading PF03928.14 KUM66589.1 - 0.1 12.6 0.1 0.34 11.0 0.1 1.9 2 0 0 2 2 2 0 Haem-degrading Pyr_redox_3 PF13738.6 KUM66590.1 - 9.2e-20 71.1 0.0 8e-18 64.7 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KUM66590.1 - 3.7e-16 59.2 0.0 1.6e-13 50.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KUM66590.1 - 6.6e-16 57.8 0.1 2.1e-13 49.5 0.1 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KUM66590.1 - 1.5e-11 44.0 0.1 3.1e-09 36.4 0.1 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KUM66590.1 - 6.6e-06 26.3 0.0 2.7e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KUM66590.1 - 1.1e-05 25.9 0.5 0.39 11.3 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KUM66590.1 - 0.00025 20.4 0.0 0.0026 17.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 KUM66590.1 - 0.00077 18.6 0.1 0.0028 16.8 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 KUM66590.1 - 0.0019 17.6 0.1 0.016 14.6 0.1 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KUM66590.1 - 0.0089 16.1 0.0 3.4 7.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase SnoaL_2 PF12680.7 KUM66590.1 - 0.0097 16.5 0.1 0.087 13.5 0.0 2.5 3 0 0 3 3 3 1 SnoaL-like domain NAD_binding_9 PF13454.6 KUM66590.1 - 0.02 14.9 0.4 1.8 8.5 0.2 2.8 2 1 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KUM66590.1 - 0.02 14.2 0.0 0.48 9.6 0.0 2.2 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KUM66590.1 - 0.025 13.3 0.1 0.13 11.0 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 KUM66590.1 - 0.029 13.9 0.0 3 7.3 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KUM66590.1 - 0.053 14.0 0.0 10 6.6 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KUM66590.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KUM66590.1 - 0.16 11.8 0.0 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KUM66590.1 - 0.18 10.9 0.1 1.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Myco_arth_vir_N PF09610.10 KUM66591.1 - 0.45 10.6 2.9 0.71 10.0 2.9 1.3 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Rrn6 PF10214.9 KUM66593.1 - 0.0015 17.1 3.6 0.0021 16.7 3.6 1.2 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor CGI-121 PF08617.10 KUM66595.1 - 1.6e-55 187.7 0.8 1.8e-55 187.5 0.8 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Bax1-I PF01027.20 KUM66596.1 - 8.7e-34 117.2 11.2 1.4e-33 116.5 11.2 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF3995 PF13160.6 KUM66596.1 - 2.3 8.6 12.0 0.13 12.6 2.8 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3995) zf-MIZ PF02891.20 KUM66597.1 - 3.2e-10 39.6 1.2 5.4e-10 38.9 0.3 1.9 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KUM66597.1 - 0.002 17.9 0.3 0.0048 16.7 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit NUMOD1 PF07453.13 KUM66597.1 - 0.067 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 NUMOD1 domain JAB PF01398.21 KUM66598.1 - 2.9e-33 114.4 0.0 5.6e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KUM66598.1 - 2e-11 44.3 0.9 3.4e-11 43.6 0.9 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KUM66598.1 - 8e-08 32.1 0.0 3.4e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Hist_deacetyl PF00850.19 KUM66599.1 - 9.2e-83 278.2 0.0 1.7e-82 277.4 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain Nsp1_C PF05064.13 KUM66600.1 - 9.8e-41 138.2 0.5 2.7e-40 136.8 0.5 1.7 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KUM66600.1 - 3.8e-09 37.3 148.7 0.0062 17.4 39.9 7.1 1 1 4 5 5 5 1 Nucleoporin FG repeat region ParB PF08775.10 KUM66600.1 - 0.034 14.6 0.5 0.07 13.6 0.5 1.4 1 0 0 1 1 1 0 ParB family Laminin_II PF06009.12 KUM66600.1 - 0.096 12.7 8.2 19 5.2 2.3 3.1 1 1 2 3 3 3 0 Laminin Domain II SGT1 PF07093.11 KUM66600.1 - 0.16 10.4 1.4 0.21 10.0 1.4 1.1 1 0 0 1 1 1 0 SGT1 protein DUF1664 PF07889.12 KUM66600.1 - 0.19 11.8 4.2 1.2 9.2 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 KUM66600.1 - 0.32 11.5 3.7 0.43 11.1 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF4407 PF14362.6 KUM66600.1 - 0.52 9.6 4.9 0.86 8.9 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 KUM66600.1 - 0.55 8.8 2.0 0.79 8.3 2.0 1.2 1 0 0 1 1 1 0 AAA domain OmpH PF03938.14 KUM66600.1 - 0.66 10.3 5.7 0.64 10.4 0.2 2.3 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4200 PF13863.6 KUM66600.1 - 0.86 10.0 4.9 2.5 8.5 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF948 PF06103.11 KUM66600.1 - 0.97 9.7 5.4 1.3 9.3 1.5 2.8 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) HIP1_clath_bdg PF16515.5 KUM66600.1 - 1.3 9.7 7.7 13 6.5 4.9 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CK2S PF15011.6 KUM66600.1 - 1.4 8.8 3.1 26 4.7 0.5 2.3 2 0 0 2 2 2 0 Casein Kinase 2 substrate Snapin_Pallidin PF14712.6 KUM66600.1 - 2.7 8.5 3.9 6.1 7.3 0.1 2.3 2 0 0 2 2 2 0 Snapin/Pallidin V-SNARE PF05008.15 KUM66600.1 - 3.3 8.2 6.1 9.1 6.7 0.2 3.0 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus APG6_N PF17675.1 KUM66600.1 - 4.5 7.8 6.6 11 6.6 5.7 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region MscS_porin PF12795.7 KUM66600.1 - 8.5 5.8 8.8 15 5.1 2.9 2.3 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF5102 PF17104.5 KUM66601.1 - 1.3e-111 373.3 2.3 2.1e-111 372.6 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) IATP PF04568.12 KUM66602.1 - 1e-35 122.1 0.6 1.1e-35 122.0 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP BLOC1_2 PF10046.9 KUM66602.1 - 0.029 14.7 0.7 0.034 14.4 0.7 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2730 PF10805.8 KUM66602.1 - 0.061 13.4 0.5 0.076 13.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF4140 PF13600.6 KUM66602.1 - 0.11 12.9 1.2 0.29 11.6 0.5 1.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ank_2 PF12796.7 KUM66603.1 - 1.4e-55 185.8 9.0 1.4e-11 44.8 0.1 6.2 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM66603.1 - 8e-48 160.2 2.8 4.3e-09 36.7 0.0 9.1 3 2 7 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.30 KUM66603.1 - 9.4e-46 152.3 6.7 5e-06 26.7 0.0 11.9 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 KUM66603.1 - 7e-42 140.9 7.7 9e-10 38.6 0.0 8.0 3 2 6 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KUM66603.1 - 2.7e-39 128.6 5.0 0.00014 22.0 0.0 11.5 12 0 0 12 12 12 8 Ankyrin repeat F-box-like PF12937.7 KUM66603.1 - 0.029 14.2 0.2 0.053 13.4 0.2 1.4 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KUM66603.1 - 0.11 12.5 1.0 0.51 10.3 1.0 2.0 1 1 0 1 1 1 0 F-box domain PTS_IIA PF02255.16 KUM66603.1 - 0.13 12.4 1.7 0.39 10.8 0.3 2.4 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF498 PF04430.14 KUM66604.1 - 2.1e-28 98.6 0.0 2.9e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) ABC_membrane PF00664.23 KUM66605.1 - 8e-34 117.5 7.8 8e-34 117.5 7.8 2.9 3 1 0 3 3 3 1 ABC transporter transmembrane region ABC_tran PF00005.27 KUM66605.1 - 1.9e-33 115.9 0.0 8.8e-33 113.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KUM66605.1 - 7.9e-08 32.0 0.2 4e-06 26.4 0.0 2.6 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KUM66605.1 - 0.0079 16.6 0.8 0.024 15.0 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 KUM66605.1 - 0.021 15.0 0.4 0.49 10.7 0.4 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KUM66605.1 - 0.023 15.0 0.4 0.17 12.2 0.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KUM66605.1 - 0.036 13.8 0.2 0.095 12.5 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KUM66605.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 KUM66605.1 - 0.12 12.4 0.1 1.3 9.0 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Alk_phosphatase PF00245.20 KUM66607.1 - 1.5e-104 350.2 0.0 1.9e-104 349.9 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KUM66607.1 - 0.00042 19.8 0.0 0.00078 18.9 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Cactin_mid PF10312.9 KUM66608.1 - 1e-62 211.4 5.7 1.7e-62 210.7 5.7 1.4 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KUM66608.1 - 7e-58 194.0 4.2 1.2e-57 193.3 4.2 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF1087 PF06465.13 KUM66608.1 - 0.023 14.7 0.3 0.079 13.0 0.3 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) SF3A2 PF16835.5 KUM66608.1 - 0.04 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) WD40 PF00400.32 KUM66610.1 - 2.3e-16 59.9 20.4 2.1e-05 25.2 0.2 7.3 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM66610.1 - 4.8e-08 33.2 0.1 0.66 10.3 0.0 5.3 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KUM66610.1 - 3.8e-05 23.7 0.0 0.23 11.3 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A zf-C2H2_aberr PF17017.5 KUM66610.1 - 0.009 16.2 0.1 0.052 13.7 0.0 2.0 2 0 0 2 2 2 1 Aberrant zinc-finger CLAMP PF14769.6 KUM66610.1 - 0.084 13.3 0.4 0.18 12.2 0.4 1.5 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Zn_ribbon_17 PF17120.5 KUM66610.1 - 0.35 10.5 9.4 1.1 9.0 9.4 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type XLF PF09302.11 KUM66611.1 - 3.7e-51 173.8 1.3 6.2e-51 173.1 1.3 1.4 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Forkhead PF00250.18 KUM66612.1 - 1.4e-20 73.3 0.0 3.1e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain Ribosomal_L34e PF01199.18 KUM66613.1 - 1e-43 147.6 2.2 1.4e-43 147.1 2.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 KUM66613.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Glyco_hydro_76 PF03663.14 KUM66614.1 - 1.8e-19 70.5 0.2 2e-12 47.3 0.0 3.0 3 1 0 3 3 3 2 Glycosyl hydrolase family 76 ABC_membrane PF00664.23 KUM66615.1 - 2.5e-54 184.8 39.4 4.3e-34 118.4 20.9 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KUM66615.1 - 9e-46 155.8 0.0 5.9e-25 88.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 KUM66615.1 - 8.7e-07 29.0 0.4 0.016 15.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 KUM66615.1 - 3.6e-06 26.6 2.7 0.17 11.3 0.9 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KUM66615.1 - 2.4e-05 23.7 0.0 0.0053 16.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.6 KUM66615.1 - 9.7e-05 22.3 0.9 0.12 12.2 0.0 3.2 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KUM66615.1 - 0.00011 22.1 0.2 0.15 12.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KUM66615.1 - 0.00018 21.9 0.5 0.54 10.6 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KUM66615.1 - 0.0009 18.9 4.2 0.32 10.8 0.1 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KUM66615.1 - 0.0022 18.5 0.3 0.34 11.4 0.1 2.8 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KUM66615.1 - 0.0026 17.9 1.9 0.25 11.4 0.0 2.6 2 0 0 2 2 2 1 Dynamin family MeaB PF03308.16 KUM66615.1 - 0.0098 14.9 0.9 2.5 7.0 0.2 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KUM66615.1 - 0.01 16.1 1.2 7.3 6.9 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 KUM66615.1 - 0.015 15.0 1.8 3.5 7.2 0.0 2.9 2 1 1 3 3 3 0 AAA ATPase domain DUF87 PF01935.17 KUM66615.1 - 0.025 14.7 1.4 0.26 11.4 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 KUM66615.1 - 0.04 14.5 0.3 23 5.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KUM66615.1 - 0.099 12.4 0.0 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 KUM66615.1 - 0.14 12.6 0.0 3.6 8.0 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KUM66615.1 - 0.39 10.9 2.4 1.4 9.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain Pes-10 PF07149.11 KUM66615.1 - 0.75 8.8 4.3 4.9 6.1 0.1 2.1 2 0 0 2 2 2 0 Pes-10 DUF1729 PF08354.10 KUM66616.1 - 0.016 14.2 0.1 0.018 14.0 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) TPP_enzyme_M PF00205.22 KUM66616.1 - 0.037 13.8 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain RicinB_lectin_2 PF14200.6 KUM66617.1 - 0.0014 19.3 0.1 0.41 11.4 0.1 2.2 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Med26 PF08711.11 KUM66617.1 - 0.22 11.6 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 TFIIS helical bundle-like domain MU117 PF15474.6 KUM66618.1 - 1.3e-18 67.7 4.6 1.3e-18 67.7 4.6 2.2 2 0 0 2 2 2 1 Meiotically up-regulated gene family La_HTH_kDCL PF18177.1 KUM66620.1 - 0.016 15.5 0.1 0.088 13.1 0.0 2.1 2 0 0 2 2 2 0 La HTH in kinetoplastid DICER domain F-box-like PF12937.7 KUM66620.1 - 0.037 13.9 0.0 0.091 12.7 0.0 1.7 1 0 0 1 1 1 0 F-box-like LRR_8 PF13855.6 KUM66620.1 - 2.3 8.1 6.9 5.9 6.7 0.6 3.6 4 0 0 4 4 4 0 Leucine rich repeat Fungus-induced PF10917.8 KUM66621.1 - 0.096 13.0 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 Fungus-induced protein DUF3328 PF11807.8 KUM66622.1 - 0.0016 18.3 1.7 0.022 14.6 0.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) Lectin_N PF03954.14 KUM66622.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain FMN_red PF03358.15 KUM66623.1 - 2.2e-29 102.2 0.0 3.1e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KUM66623.1 - 1.1e-07 31.8 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Transferase PF02458.15 KUM66624.1 - 4.2e-33 114.7 0.0 1.1e-23 83.7 0.0 3.0 2 1 0 2 2 2 2 Transferase family Sugar_tr PF00083.24 KUM66625.1 - 2.1e-31 109.3 27.1 7.2e-24 84.5 7.2 2.5 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 KUM66625.1 - 5.9e-27 94.5 27.6 5.9e-27 94.5 27.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.6 KUM66625.1 - 0.92 10.0 12.0 6.8 7.2 0.1 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) DUF2205 PF10224.9 KUM66626.1 - 3.5e-34 116.6 3.0 3.5e-34 116.6 3.0 1.6 2 0 0 2 2 2 1 Short coiled-coil protein HALZ PF02183.18 KUM66626.1 - 0.014 15.6 5.0 0.038 14.2 0.2 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF2884 PF11101.8 KUM66626.1 - 0.017 14.6 1.3 0.024 14.2 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DivIC PF04977.15 KUM66626.1 - 0.026 14.3 1.9 0.042 13.6 1.9 1.4 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 KUM66626.1 - 0.027 15.1 2.9 0.04 14.6 2.9 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Baculo_PEP_C PF04513.12 KUM66626.1 - 0.091 12.8 0.4 0.13 12.3 0.4 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tup_N PF08581.10 KUM66626.1 - 0.095 13.0 2.7 6.6 7.1 0.1 2.2 1 1 1 2 2 2 0 Tup N-terminal bZIP_1 PF00170.21 KUM66626.1 - 0.18 11.9 5.8 0.62 10.2 5.6 1.9 1 1 1 2 2 2 0 bZIP transcription factor DUF5320 PF17253.2 KUM66626.1 - 0.19 12.8 2.7 0.33 12.1 1.3 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5320) 14-3-3 PF00244.20 KUM66627.1 - 7.9e-105 349.3 5.3 9.2e-105 349.0 5.3 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 KUM66627.1 - 0.096 11.1 3.4 0.14 10.5 3.4 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 RRM_1 PF00076.22 KUM66628.1 - 8.8e-16 57.5 0.0 1.3e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KUM66628.1 - 0.0005 19.7 0.0 0.00074 19.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KUM66628.1 - 0.027 14.3 0.0 0.053 13.4 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KUM66628.1 - 0.033 14.2 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif HMA PF00403.26 KUM66628.1 - 0.12 12.9 0.0 0.19 12.2 0.0 1.4 1 1 0 1 1 1 0 Heavy-metal-associated domain XFP_N PF09364.10 KUM66628.1 - 0.16 10.8 0.0 0.79 8.5 0.0 1.8 1 1 0 2 2 2 0 XFP N-terminal domain ER_lumen_recept PF00810.18 KUM66629.1 - 2.2e-44 151.9 8.1 3.4e-44 151.2 8.1 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KUM66629.1 - 0.017 14.9 0.2 0.017 14.9 0.2 3.9 5 1 0 5 5 5 0 PQ loop repeat Tlr3_TMD PF17968.1 KUM66629.1 - 0.19 11.9 2.8 0.6 10.3 2.8 1.9 1 0 0 1 1 1 0 Toll-like receptor 3 trans-membrane domain Myb_DNA-bind_4 PF13837.6 KUM66630.1 - 0.0088 16.4 2.6 0.012 16.0 0.2 2.2 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain ATP-synt_ab PF00006.25 KUM66631.1 - 6.5e-30 104.4 0.0 1e-29 103.8 0.0 1.3 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Myb_DNA-binding PF00249.31 KUM66632.1 - 8.5e-16 57.9 4.6 3.6e-09 36.7 0.7 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KUM66632.1 - 4.7e-10 39.6 1.5 6.4e-06 26.3 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KUM66632.1 - 0.037 13.9 1.3 0.054 13.4 1.3 1.4 1 1 0 1 1 1 0 Myb DNA-binding like RHIM PF12721.7 KUM66632.1 - 0.06 13.8 3.5 0.12 12.8 3.5 1.6 1 0 0 1 1 1 0 RIP homotypic interaction motif Transp_cyt_pur PF02133.15 KUM66633.1 - 1.5e-16 60.3 41.7 2.9e-16 59.3 41.7 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COX5B PF01215.19 KUM66634.1 - 9.9e-56 187.0 0.0 1.3e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-UBP PF02148.19 KUM66634.1 - 0.034 14.5 0.4 0.052 13.9 0.4 1.2 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Myb_DNA-bind_6 PF13921.6 KUM66635.1 - 1.8e-07 31.3 2.7 0.0014 18.8 0.4 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KUM66635.1 - 5.8e-07 29.6 1.1 1.3e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain PROCN PF08083.11 KUM66636.1 - 2e-233 774.4 8.4 2e-233 774.4 8.4 1.9 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KUM66636.1 - 1.9e-126 420.3 1.4 3.6e-126 419.4 1.4 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KUM66636.1 - 1.8e-85 284.7 1.0 8.9e-58 194.7 0.1 3.0 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KUM66636.1 - 2.8e-80 267.6 2.3 7.9e-80 266.2 2.3 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KUM66636.1 - 4.5e-71 237.2 0.1 1e-70 236.0 0.1 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 KUM66636.1 - 1e-47 161.1 0.0 3.2e-47 159.5 0.0 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 KUM66636.1 - 7.1e-47 157.7 0.2 2e-46 156.2 0.2 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end_hint PF05203.16 KUM66636.1 - 2.2e-10 40.9 1.2 4.1e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 Hom_end-associated Hint Slx4 PF09494.10 KUM66637.1 - 8.3e-26 89.7 0.0 1.5e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease Zn_clus PF00172.18 KUM66638.1 - 0.00011 22.2 9.8 0.0002 21.4 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YabA PF06156.13 KUM66638.1 - 0.00048 20.7 1.2 0.00092 19.8 1.2 1.4 1 0 0 1 1 1 1 Initiation control protein YabA ADIP PF11559.8 KUM66638.1 - 0.00049 20.2 3.5 0.00082 19.5 3.5 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding ZapB PF06005.12 KUM66638.1 - 0.0005 20.5 7.1 0.0012 19.2 7.1 1.5 2 0 0 2 2 1 1 Cell division protein ZapB DUF4201 PF13870.6 KUM66638.1 - 0.00084 19.1 1.5 0.00084 19.1 1.5 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) TSC22 PF01166.18 KUM66638.1 - 0.001 19.3 2.9 0.0023 18.2 2.9 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family Jnk-SapK_ap_N PF09744.9 KUM66638.1 - 0.0012 19.1 1.4 0.002 18.4 1.4 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 MctB PF11382.8 KUM66638.1 - 0.0028 17.4 0.6 0.0035 17.1 0.6 1.1 1 0 0 1 1 1 1 Copper transport outer membrane protein, MctB DUF3450 PF11932.8 KUM66638.1 - 0.0035 16.7 3.7 0.0048 16.2 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DivIC PF04977.15 KUM66638.1 - 0.0053 16.5 4.5 0.0091 15.7 4.5 1.4 1 0 0 1 1 1 1 Septum formation initiator UPF0242 PF06785.11 KUM66638.1 - 0.0063 16.7 1.3 0.0083 16.3 1.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Ax_dynein_light PF10211.9 KUM66638.1 - 0.0075 16.2 1.5 0.011 15.6 1.5 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain TMF_DNA_bd PF12329.8 KUM66638.1 - 0.0093 15.9 4.2 0.016 15.2 4.2 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF4795 PF16043.5 KUM66638.1 - 0.0094 15.6 1.0 0.0094 15.6 1.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) Sipho_Gp157 PF05565.11 KUM66638.1 - 0.016 15.2 0.3 0.025 14.6 0.3 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 FliD_C PF07195.12 KUM66638.1 - 0.023 14.1 1.6 0.033 13.6 1.6 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF3552 PF12072.8 KUM66638.1 - 0.025 14.0 3.7 0.041 13.3 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) RmuC PF02646.16 KUM66638.1 - 0.028 13.6 1.9 0.042 13.0 1.9 1.2 1 0 0 1 1 1 0 RmuC family CENP-H PF05837.12 KUM66638.1 - 0.036 14.5 2.5 0.036 14.5 2.5 1.5 2 0 0 2 2 1 0 Centromere protein H (CENP-H) Prefoldin PF02996.17 KUM66638.1 - 0.045 13.7 4.5 0.063 13.2 4.5 1.2 1 0 0 1 1 1 0 Prefoldin subunit GIT_CC PF16559.5 KUM66638.1 - 0.054 13.4 8.4 0.099 12.5 8.4 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_2 PF07716.15 KUM66638.1 - 0.081 13.0 9.9 0.16 12.0 9.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper DUF4407 PF14362.6 KUM66638.1 - 0.096 12.0 0.4 0.097 12.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 KUM66638.1 - 0.15 12.3 0.4 0.25 11.6 0.4 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PspA_IM30 PF04012.12 KUM66638.1 - 0.19 11.3 5.9 0.33 10.5 5.9 1.3 1 0 0 1 1 1 0 PspA/IM30 family NYD-SP28_assoc PF14775.6 KUM66638.1 - 0.21 11.7 3.5 0.48 10.6 3.5 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Synaptobrevin PF00957.21 KUM66638.1 - 0.25 11.1 2.1 0.58 10.0 2.0 1.6 2 0 0 2 2 1 0 Synaptobrevin DASH_Dam1 PF08653.10 KUM66638.1 - 0.32 10.8 1.2 0.48 10.3 1.2 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 DUF3847 PF12958.7 KUM66638.1 - 0.65 10.1 7.4 0.19 11.9 4.6 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF3847) TPR_2 PF07719.17 KUM66640.1 - 1.9e-06 27.5 3.6 0.015 15.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KUM66640.1 - 3.3e-06 26.7 3.8 0.00014 21.5 0.0 3.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KUM66640.1 - 4.1e-06 27.2 0.0 0.19 12.7 0.0 3.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KUM66640.1 - 0.0036 17.0 0.1 0.0096 15.6 0.0 1.8 2 0 0 2 2 2 1 TPR repeat SET PF00856.28 KUM66641.1 - 0.098 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 SET domain Methyltransf_23 PF13489.6 KUM66642.1 - 7.7e-16 58.4 0.0 2.3e-15 56.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM66642.1 - 9.9e-10 39.0 0.0 3.2e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM66642.1 - 0.00029 21.4 0.0 0.0011 19.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM66642.1 - 0.00041 21.0 0.0 0.0087 16.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM66642.1 - 0.0012 18.7 0.0 0.0034 17.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KUM66642.1 - 0.0033 16.9 0.0 0.0093 15.4 0.0 1.8 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KUM66642.1 - 0.011 15.3 0.0 0.049 13.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KUM66642.1 - 0.012 14.9 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase domain Ubie_methyltran PF01209.18 KUM66642.1 - 0.089 12.1 0.0 2.3 7.5 0.0 2.4 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family NAD_binding_4 PF07993.12 KUM66643.1 - 1.1e-35 123.1 0.0 1.7e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KUM66643.1 - 1.2e-27 96.6 0.0 1.9e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KUM66643.1 - 7.4e-10 38.7 0.0 1.8e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KUM66643.1 - 2.5e-08 34.2 0.1 5.3e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KUM66643.1 - 0.0023 17.9 0.0 0.0081 16.1 0.0 1.9 1 0 0 1 1 1 1 KR domain Aldo_ket_red PF00248.21 KUM66644.1 - 1.9e-42 145.4 0.0 1.5e-41 142.5 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family DUF5033 PF16436.5 KUM66646.1 - 0.052 13.5 0.1 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5033) Fungal_trans PF04082.18 KUM66649.1 - 1.3e-27 96.5 0.0 2.1e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM66649.1 - 1.8e-05 24.7 8.1 1.8e-05 24.7 8.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KUM66650.1 - 2e-40 138.8 28.0 5.6e-40 137.4 27.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Fe-S_assembly PF04384.13 KUM66650.1 - 0.072 13.7 0.1 0.14 12.8 0.1 1.4 1 0 0 1 1 1 0 Iron-sulphur cluster assembly Mce4_CUP1 PF11887.8 KUM66651.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative PH PF00169.29 KUM66652.1 - 9.5e-12 45.4 0.0 5.6e-11 42.9 0.0 2.2 1 1 0 1 1 1 1 PH domain SAM_2 PF07647.17 KUM66652.1 - 7.6e-08 32.3 0.1 1.3e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 KUM66652.1 - 6.7e-07 29.1 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KUM66652.1 - 2.5e-06 27.0 0.1 5.1e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SAM_1 PF00536.30 KUM66652.1 - 0.0049 17.3 0.1 0.0094 16.4 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 KUM66652.1 - 0.0086 16.5 0.0 0.026 14.9 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KUM66652.1 - 0.089 13.1 0.0 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain DUF2464 PF10240.9 KUM66652.1 - 0.81 9.2 4.3 0.4 10.2 0.6 2.4 2 1 0 2 2 2 0 Multivesicular body subunit 12 Ribosomal_L14 PF00238.19 KUM66653.1 - 3.6e-34 117.5 0.0 4.3e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Endonuc-FokI_C PF09254.11 KUM66653.1 - 0.078 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal NIF PF03031.18 KUM66655.1 - 7.6e-42 142.7 0.1 1.1e-41 142.3 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase F-box-like PF12937.7 KUM66656.1 - 0.013 15.4 0.1 0.055 13.4 0.0 2.1 2 1 0 2 2 2 0 F-box-like EspF PF04806.12 KUM66657.1 - 0.0078 16.6 3.7 0.027 14.9 3.7 1.9 1 0 0 1 1 1 1 EspF protein repeat ANAPC4_WD40 PF12894.7 KUM66657.1 - 0.012 15.9 0.0 3.6 8.0 0.0 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KUM66657.1 - 0.055 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 F-box domain TFIIIC_delta PF12657.7 KUM66657.1 - 0.068 13.1 0.0 0.76 9.7 0.0 2.5 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Fungal_trans PF04082.18 KUM66658.1 - 4.9e-15 55.3 0.0 1.2e-14 54.0 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM66658.1 - 1.2e-06 28.5 6.9 2.8e-06 27.4 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KUM66661.1 - 6.8e-23 81.4 0.0 4.5e-12 45.9 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KUM66661.1 - 2.4e-10 40.2 1.3 8.8e-05 21.9 0.1 3.5 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 KUM66661.1 - 1.7e-05 24.3 0.0 0.63 9.3 0.0 3.2 3 0 0 3 3 3 3 Kinase-like APH PF01636.23 KUM66661.1 - 0.0032 17.4 0.1 0.009 16.0 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KUM66661.1 - 0.041 13.2 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family eIF-1a PF01176.19 KUM66662.1 - 1.8e-16 59.7 0.5 2.6e-16 59.2 0.5 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Sugar_tr PF00083.24 KUM66663.1 - 7.6e-110 367.8 24.6 9e-110 367.6 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM66663.1 - 3.3e-16 59.2 35.6 3.2e-09 36.2 10.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Metallophos PF00149.28 KUM66665.1 - 1.5e-30 107.3 0.0 4.6e-22 79.5 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KUM66665.1 - 0.2 12.1 0.2 0.52 10.8 0.2 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain COA2 PF17051.5 KUM66666.1 - 0.0083 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 NSP2-B_epitope PF14757.6 KUM66666.1 - 0.04 13.6 0.3 0.054 13.2 0.3 1.1 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein ALG3 PF05208.13 KUM66667.1 - 1.3e-133 445.9 14.5 1.6e-133 445.6 14.5 1.0 1 0 0 1 1 1 1 ALG3 protein DUF4381 PF14316.6 KUM66668.1 - 0.035 14.3 0.1 0.054 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TPR_2 PF07719.17 KUM66669.1 - 8.6e-14 50.5 6.0 0.003 17.5 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KUM66669.1 - 2.7e-09 36.4 1.3 0.056 13.3 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KUM66669.1 - 2.1e-07 30.5 3.0 0.072 12.8 0.0 5.0 4 0 0 4 4 4 2 TPR repeat TPR_19 PF14559.6 KUM66669.1 - 1.2e-05 25.7 1.1 0.0016 18.9 0.2 4.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KUM66669.1 - 0.00016 22.2 16.0 0.16 12.6 0.8 6.4 5 2 0 5 5 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 KUM66669.1 - 0.00027 21.3 10.3 0.87 10.4 1.7 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KUM66669.1 - 0.00031 21.0 11.6 0.0023 18.2 1.3 4.4 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KUM66669.1 - 0.001 19.7 19.0 2.4 9.2 0.0 7.8 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KUM66669.1 - 0.0024 17.9 0.2 15 6.1 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat Ofd1_CTDD PF10637.9 KUM66669.1 - 0.0029 17.0 0.1 0.069 12.5 0.0 2.1 2 0 0 2 2 2 1 Oxoglutarate and iron-dependent oxygenase degradation C-term TPR_7 PF13176.6 KUM66669.1 - 0.0045 16.9 6.5 16 5.8 0.2 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR_3 PF13812.6 KUM66669.1 - 0.12 12.5 1.2 0.22 11.6 0.1 2.0 2 0 0 2 2 2 0 Pentatricopeptide repeat domain TPR_17 PF13431.6 KUM66669.1 - 0.14 12.6 3.3 22 5.7 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KUM66669.1 - 0.77 9.7 7.8 1.6 8.7 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3337 PF11816.8 KUM66670.1 - 5.5e-55 185.9 0.0 9.4e-55 185.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KUM66670.1 - 2.8e-17 62.7 14.8 5.9e-05 23.8 0.2 7.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM66670.1 - 0.011 16.0 0.2 0.3 11.4 0.1 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KUM66670.1 - 0.028 13.4 0.0 0.13 11.2 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KUM66670.1 - 0.15 10.6 0.3 1.4 7.5 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 EF-hand_6 PF13405.6 KUM66672.1 - 1e-08 34.4 0.1 0.0056 16.5 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KUM66672.1 - 0.0018 17.7 0.0 0.0067 15.9 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KUM66672.1 - 0.0034 17.8 1.8 0.13 12.8 0.2 2.9 1 1 2 3 3 3 2 EF-hand domain pair ANAPC4_WD40 PF12894.7 KUM66673.1 - 8.4e-05 22.8 0.0 0.12 12.7 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 KUM66673.1 - 0.0004 20.1 0.1 0.015 14.9 0.1 2.4 2 0 0 2 2 2 1 CNH domain Coatomer_WDAD PF04053.14 KUM66673.1 - 0.0075 15.4 0.0 0.03 13.4 0.0 1.9 1 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KUM66673.1 - 0.049 14.5 0.1 7.4 7.6 0.0 3.5 3 1 1 4 4 4 0 WD domain, G-beta repeat Hira PF07569.11 KUM66673.1 - 0.049 13.3 0.1 0.59 9.8 0.0 2.5 3 0 0 3 3 3 0 TUP1-like enhancer of split MMS1_N PF10433.9 KUM66673.1 - 0.12 11.0 0.0 2 7.0 0.0 2.4 2 1 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term OB_NTP_bind PF07717.16 KUM66674.1 - 1.4e-24 86.3 0.1 1.1e-23 83.4 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KUM66674.1 - 3.2e-19 69.2 0.3 8.3e-19 67.9 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KUM66674.1 - 7.8e-10 39.1 0.0 2.2e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KUM66674.1 - 5.6e-07 29.5 0.2 1e-06 28.6 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KUM66674.1 - 0.00073 19.8 0.0 0.0027 18.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KUM66674.1 - 0.00096 18.8 0.3 0.0031 17.2 0.3 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_23 PF13476.6 KUM66674.1 - 0.023 15.2 0.0 0.054 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KUM66674.1 - 0.024 14.3 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KUM66674.1 - 0.045 12.8 0.0 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KUM66674.1 - 0.05 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KUM66674.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Flavi_DEAD PF07652.14 KUM66674.1 - 0.14 12.1 0.1 0.39 10.7 0.1 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF5082 PF16888.5 KUM66675.1 - 1.7 9.0 8.6 1.2 9.4 1.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) SKA2 PF16740.5 KUM66675.1 - 2.1 8.2 5.9 2.3 8.0 0.3 3.4 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 APG6_N PF17675.1 KUM66675.1 - 4.1 7.9 11.8 9.7 6.7 2.9 3.2 3 1 0 3 3 3 0 Apg6 coiled-coil region Lipase_3 PF01764.25 KUM66676.1 - 1.1e-34 119.3 0.0 1.6e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KUM66676.1 - 6.7e-23 80.5 0.3 1.5e-22 79.4 0.3 1.7 1 0 0 1 1 1 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 KUM66676.1 - 8.2e-07 28.5 0.0 1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KUM66676.1 - 2.3e-05 25.1 0.5 3e-05 24.8 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KUM66676.1 - 0.00025 20.7 0.0 0.00046 19.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase Thioesterase PF00975.20 KUM66676.1 - 0.00091 19.4 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Cutinase PF01083.22 KUM66676.1 - 0.0032 17.5 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 KUM66676.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KUM66676.1 - 0.052 13.2 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.8 KUM66676.1 - 0.055 13.0 0.2 0.52 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Ser_hydrolase PF06821.13 KUM66676.1 - 0.067 13.0 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF676 PF05057.14 KUM66676.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PRMT5_TIM PF17285.2 KUM66677.1 - 6.6e-71 238.5 0.0 8.8e-71 238.1 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 KUM66677.1 - 1.9e-64 216.7 0.0 4.6e-64 215.4 0.0 1.7 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KUM66677.1 - 3.4e-56 189.9 0.2 5.7e-56 189.2 0.2 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain RNA_pol_Rpc34 PF05158.12 KUM66678.1 - 0.013 14.9 0.9 0.031 13.7 0.9 1.6 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit DUF4661 PF15576.6 KUM66678.1 - 3.2 7.6 5.6 3.9 7.3 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Peptidase_S10 PF00450.22 KUM66679.1 - 8.2e-92 308.8 2.5 9.8e-92 308.5 2.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DSPc PF00782.20 KUM66680.1 - 1e-27 96.6 0.0 2.6e-20 72.6 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KUM66680.1 - 7.6e-05 22.4 0.0 0.0027 17.3 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Mlh1_C PF16413.5 KUM66681.1 - 3.9e-98 328.1 0.0 6.6e-98 327.4 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KUM66681.1 - 4.6e-33 113.4 0.1 7.5e-33 112.7 0.1 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KUM66681.1 - 1.2e-13 51.1 0.0 2.9e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KUM66681.1 - 4.1e-08 33.7 0.0 1.3e-07 32.1 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_6 PF12774.7 KUM66682.1 - 2.9e-123 411.0 0.0 5.4e-122 406.9 0.0 2.8 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KUM66682.1 - 3.4e-123 412.3 5.8 3.4e-123 412.3 5.8 6.0 7 1 0 7 7 7 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KUM66682.1 - 1.1e-113 380.4 8.2 1.1e-113 380.4 8.2 3.9 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KUM66682.1 - 5.7e-75 251.2 1.0 5.7e-75 251.2 1.0 3.7 3 1 1 4 4 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 KUM66682.1 - 1.6e-65 221.0 0.0 4.3e-65 219.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KUM66682.1 - 6.4e-42 143.1 0.0 1.3e-36 125.8 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 KUM66682.1 - 1.8e-40 139.1 5.7 3.7e-40 138.0 5.7 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KUM66682.1 - 2e-30 105.8 0.0 4.6e-30 104.6 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KUM66682.1 - 2.2e-30 105.2 0.0 8.9e-25 87.1 0.0 4.5 4 0 0 4 4 3 2 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KUM66682.1 - 3.3e-30 104.9 0.2 1.2e-09 38.3 0.0 6.4 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KUM66682.1 - 7.1e-18 64.9 0.0 3.2e-17 62.8 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KUM66682.1 - 9.3e-15 55.2 0.0 9.5e-05 22.8 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KUM66682.1 - 4.2e-14 53.0 0.0 0.009 16.3 0.0 6.6 5 0 0 5 5 5 2 AAA domain AAA_18 PF13238.6 KUM66682.1 - 3.8e-10 40.4 0.2 0.047 14.2 0.0 5.2 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 KUM66682.1 - 1.1e-08 35.3 0.9 0.47 10.6 0.1 5.1 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.6 KUM66682.1 - 2.4e-08 34.5 4.4 1.2 9.5 0.0 8.2 8 0 0 8 8 7 1 AAA ATPase domain ABC_tran PF00005.27 KUM66682.1 - 6.7e-06 26.7 0.1 1.1 9.8 0.1 4.8 3 0 0 3 3 3 2 ABC transporter T2SSE PF00437.20 KUM66682.1 - 8.8e-06 25.0 0.0 0.012 14.7 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_lid_1 PF17857.1 KUM66682.1 - 2e-05 24.7 0.1 0.00059 20.0 0.0 3.2 3 0 0 3 3 2 1 AAA+ lid domain AAA_29 PF13555.6 KUM66682.1 - 0.0002 21.0 0.0 2.3 8.0 0.0 3.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KUM66682.1 - 0.00023 20.6 0.9 0.58 9.5 0.0 3.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 KUM66682.1 - 0.00036 20.5 0.0 14 5.5 0.0 3.9 3 0 0 3 3 3 0 RsgA GTPase AAA_30 PF13604.6 KUM66682.1 - 0.00055 19.7 1.6 22 4.7 0.0 5.2 5 0 0 5 5 5 0 AAA domain AAA_25 PF13481.6 KUM66682.1 - 0.002 17.7 0.0 0.45 10.1 0.0 3.6 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 KUM66682.1 - 0.0028 17.4 0.8 0.51 10.1 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein Rad17 PF03215.15 KUM66682.1 - 0.0047 16.9 1.4 4.8 7.1 0.0 4.3 5 0 0 5 5 3 0 Rad17 P-loop domain AAA_24 PF13479.6 KUM66682.1 - 0.0054 16.5 1.1 26 4.4 0.0 4.7 5 0 0 5 5 4 0 AAA domain Zeta_toxin PF06414.12 KUM66682.1 - 0.0066 15.7 0.7 6.2 6.1 0.2 4.0 4 0 0 4 4 4 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KUM66682.1 - 0.0084 15.5 0.0 2.1 7.7 0.0 3.5 3 0 0 3 3 3 1 FtsK/SpoIIIE family DUF3867 PF12983.7 KUM66682.1 - 0.014 15.5 0.4 0.014 15.5 0.4 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF3867) RNA_helicase PF00910.22 KUM66682.1 - 0.016 15.6 0.2 39 4.7 0.0 4.5 4 0 0 4 4 4 0 RNA helicase BRE1 PF08647.11 KUM66682.1 - 0.018 15.1 0.3 0.018 15.1 0.3 4.8 3 0 0 3 3 2 0 BRE1 E3 ubiquitin ligase AAA_19 PF13245.6 KUM66682.1 - 0.019 15.3 6.5 0.21 11.9 0.0 4.6 5 0 0 5 5 3 0 AAA domain Vps23_core PF09454.10 KUM66682.1 - 0.036 14.0 0.6 2.3 8.2 0.5 3.0 2 0 0 2 2 2 0 Vps23 core domain MbeB_N PF04837.12 KUM66682.1 - 0.13 12.5 2.2 1.8 9.0 0.1 3.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region DUF3762 PF12591.8 KUM66682.1 - 0.17 12.2 0.1 0.74 10.1 0.1 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF3762) COG2 PF06148.11 KUM66682.1 - 0.23 11.6 0.0 0.23 11.6 0.0 5.8 5 0 0 5 5 4 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_11 PF13086.6 KUM66682.1 - 1.3 8.7 9.6 1.7 8.4 0.0 3.7 3 0 0 3 3 3 0 AAA domain CENP-O PF09496.10 KUM66682.1 - 1.4 8.8 5.5 5.9 6.8 5.5 2.1 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component Atg14 PF10186.9 KUM66682.1 - 6.8 5.7 11.0 1.9 7.5 5.6 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 RPW8 PF05659.11 KUM66682.1 - 8.4 6.1 8.0 84 2.8 3.9 4.4 4 0 0 4 4 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Svf1_C PF17187.4 KUM66683.1 - 8.3e-59 198.1 0.4 2e-58 196.9 0.0 1.8 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KUM66683.1 - 1.5e-58 197.5 0.1 2.3e-58 196.9 0.1 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Ribosomal_L11_N PF03946.14 KUM66684.1 - 2.8e-26 91.1 0.1 4.5e-26 90.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KUM66684.1 - 8e-26 90.3 0.0 1.2e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Pkinase PF00069.25 KUM66685.1 - 4.6e-45 154.0 0.0 1e-41 143.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KUM66685.1 - 2.7e-19 69.5 0.0 7.4e-19 68.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KUM66685.1 - 0.035 14.0 0.4 0.069 13.1 0.4 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KUM66685.1 - 0.059 12.3 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain SAB PF04382.13 KUM66685.1 - 0.98 9.6 4.4 0.41 10.7 0.6 2.4 3 0 0 3 3 3 0 SAB domain Mito_carr PF00153.27 KUM66686.1 - 1.3e-41 140.4 2.7 3.1e-15 55.9 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2275 PF10039.9 KUM66686.1 - 0.038 14.1 0.0 0.66 10.0 0.0 2.4 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2275) AMP-binding PF00501.28 KUM66689.1 - 1.6e-144 481.7 0.0 2.5e-75 253.7 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KUM66689.1 - 2.6e-62 211.0 0.0 7.8e-28 97.3 0.0 3.4 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.25 KUM66689.1 - 3.6e-16 59.3 4.9 4.4e-08 33.4 0.1 3.0 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KUM66689.1 - 8.7e-07 29.8 0.0 0.0036 18.2 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain MatE PF01554.18 KUM66690.1 - 8.1e-45 152.4 34.2 1.9e-30 105.7 9.9 2.6 3 0 0 3 3 3 2 MatE TFCD_C PF12612.8 KUM66692.1 - 5.9e-10 39.3 0.0 1.3e-08 34.9 0.0 2.0 2 0 0 2 2 2 2 Tubulin folding cofactor D C terminal IFRD PF05004.13 KUM66693.1 - 6.6e-05 22.2 1.0 6.6e-05 22.2 1.0 3.0 3 0 0 3 3 3 2 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 KUM66693.1 - 0.00021 21.3 4.2 0.64 10.4 0.0 5.9 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 KUM66693.1 - 0.0055 17.1 0.4 4.5 7.7 0.0 4.1 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 KUM66693.1 - 2.3 8.8 14.2 1.9 9.1 0.0 6.5 8 0 0 8 8 8 0 HEAT-like repeat Glyco_hydro_18 PF00704.28 KUM66694.1 - 1.7e-49 169.3 8.5 9.8e-48 163.5 4.5 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 LysM PF01476.20 KUM66694.1 - 3.6e-08 33.3 0.9 0.00083 19.4 0.2 2.8 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KUM66694.1 - 5.3e-07 30.0 12.4 5.3e-07 30.0 12.4 3.8 3 1 0 3 3 3 1 Chitin recognition protein Pkinase PF00069.25 KUM66697.1 - 3.2e-58 197.2 0.0 5.2e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM66697.1 - 1.5e-34 119.5 0.0 2.4e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KUM66697.1 - 1.4e-28 98.8 16.5 1e-15 57.5 4.2 2.9 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KUM66697.1 - 1.3e-20 73.0 29.2 3e-12 46.2 9.5 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KUM66697.1 - 4e-14 53.1 2.2 1.9e-13 50.9 1.5 2.6 3 0 0 3 3 2 1 Protein kinase C terminal domain C2 PF00168.30 KUM66697.1 - 8.2e-06 26.1 0.0 1.6e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 KUM66697.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KUM66697.1 - 0.087 11.7 0.7 0.29 10.0 0.8 1.7 1 1 0 1 1 1 0 Haspin like kinase domain TFIIA PF03153.13 KUM66697.1 - 2.1 8.2 16.5 4.5 7.2 16.5 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Uds1 PF15456.6 KUM66697.1 - 3.1 8.0 5.3 1.1 9.4 0.6 2.4 2 0 0 2 2 2 0 Up-regulated During Septation zf-RING_9 PF13901.6 KUM66697.1 - 4.9 7.1 22.9 1.9 8.5 8.2 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Ank_2 PF12796.7 KUM66699.1 - 2e-31 108.4 0.0 1.6e-14 54.2 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KUM66699.1 - 1.9e-24 83.0 0.0 0.001 19.4 0.0 7.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KUM66699.1 - 3.8e-21 74.9 0.4 6.1e-06 26.4 0.0 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KUM66699.1 - 3.7e-18 65.6 0.0 8.1e-05 23.1 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KUM66699.1 - 5e-16 58.3 0.0 0.046 14.2 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat DUF4349 PF14257.6 KUM66699.1 - 0.13 11.6 0.4 0.47 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Fungal_trans PF04082.18 KUM66701.1 - 5.2e-42 143.7 0.2 9.9e-42 142.8 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM66701.1 - 4.7e-08 33.0 8.2 9.4e-08 32.1 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.29 KUM66701.1 - 0.0032 17.3 4.5 0.0032 17.3 4.5 1.8 2 0 0 2 2 2 1 PHD-finger DUF3473 PF11959.8 KUM66701.1 - 0.047 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) Beta-lactamase PF00144.24 KUM66703.1 - 1.3e-48 165.9 0.0 1.9e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KUM66703.1 - 4.5e-08 33.5 0.0 7.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Esterase_phd PF10503.9 KUM66705.1 - 0.00032 20.3 0.2 0.00086 18.9 0.1 1.8 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KUM66705.1 - 0.043 13.3 0.5 0.096 12.2 0.5 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KUM66705.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold RhoGEF PF00621.20 KUM66707.1 - 5.2e-22 79.0 0.0 5.3e-21 75.7 0.0 2.2 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.8 KUM66707.1 - 2.1e-06 27.6 0.0 3.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Nod1 PF17114.5 KUM66707.1 - 0.00035 20.8 0.0 0.0012 19.1 0.0 1.9 1 0 0 1 1 1 1 Gef2-related medial cortical node protein Nod1 FAM184 PF15665.5 KUM66707.1 - 0.02 14.6 0.8 0.068 12.9 0.8 1.8 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B ATP_bind_3 PF01171.20 KUM66708.1 - 2.9e-37 128.2 0.0 1.7e-36 125.7 0.0 2.1 1 1 0 1 1 1 1 PP-loop family Zn_clus PF00172.18 KUM66710.1 - 5.8e-08 32.7 10.3 9.2e-08 32.1 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 KUM66711.1 - 3.4e-25 87.7 0.5 1.9e-11 43.6 0.5 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KUM66711.1 - 2e-05 24.2 0.0 0.0018 17.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KUM66711.1 - 0.00014 21.6 0.0 0.39 10.6 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 KUM66711.1 - 0.017 14.9 0.0 0.066 13.0 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4523) Limkain-b1 PF11608.8 KUM66711.1 - 0.049 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 PHM7_cyt PF14703.6 KUM66711.1 - 0.47 10.7 4.4 3.8 7.7 0.0 3.1 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter ATP-synt_D PF01813.17 KUM66712.1 - 1.9e-63 213.9 2.5 3.6e-57 193.4 0.4 2.2 2 0 0 2 2 2 2 ATP synthase subunit D TPR_14 PF13428.6 KUM66713.1 - 1.2e-16 59.9 20.2 0.65 11.0 0.0 12.6 10 3 4 14 14 13 4 Tetratricopeptide repeat TPR_19 PF14559.6 KUM66713.1 - 7.7e-10 39.1 2.1 0.14 12.7 0.0 6.7 6 1 1 7 7 6 1 Tetratricopeptide repeat Suf PF05843.14 KUM66713.1 - 2.1e-09 37.8 16.7 0.019 15.0 0.2 6.3 5 2 1 6 6 6 4 Suppressor of forked protein (Suf) TPR_15 PF13429.6 KUM66713.1 - 2.7e-08 33.4 4.6 7.8e-05 22.0 0.9 4.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KUM66713.1 - 2.8e-08 33.3 8.1 0.026 14.7 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KUM66713.1 - 5.9e-08 32.7 13.2 0.26 11.3 0.1 7.2 6 2 1 7 7 7 2 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 KUM66713.1 - 3.7e-06 26.6 19.2 0.97 9.7 0.0 8.6 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 KUM66713.1 - 1.1e-05 25.6 6.0 0.68 10.3 0.0 7.0 7 1 0 7 7 7 1 Tetratricopeptide repeat SNAP PF14938.6 KUM66713.1 - 2.1e-05 24.1 1.1 0.012 15.1 0.1 4.3 4 1 1 5 5 5 1 Soluble NSF attachment protein, SNAP MIT PF04212.18 KUM66713.1 - 0.00073 19.6 0.0 0.96 9.6 0.1 5.0 5 0 0 5 5 4 1 MIT (microtubule interacting and transport) domain NRDE-2 PF08424.10 KUM66713.1 - 0.0034 16.5 9.9 0.073 12.2 0.3 5.1 2 2 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_17 PF13431.6 KUM66713.1 - 0.0055 17.0 8.0 0.059 13.8 0.0 5.7 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KUM66713.1 - 0.0092 16.5 0.0 24 5.9 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 KUM66713.1 - 0.05 13.3 0.1 0.85 9.3 0.1 2.8 3 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_6 PF13174.6 KUM66713.1 - 0.052 14.2 10.9 1.2 9.9 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat CKAP2_C PF15297.6 KUM66713.1 - 0.16 11.0 0.2 0.32 10.0 0.2 1.4 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus HAT PF02184.16 KUM66713.1 - 0.17 11.9 4.9 3 7.9 0.0 5.3 7 0 0 7 7 4 0 HAT (Half-A-TPR) repeat TPR_10 PF13374.6 KUM66713.1 - 1 9.3 7.7 1.4e+02 2.6 0.4 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Sec7 PF01369.20 KUM66714.1 - 6.5e-62 208.5 0.0 1e-61 207.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KUM66714.1 - 2.6e-19 69.7 0.4 2.8e-18 66.3 0.0 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KUM66714.1 - 0.0032 17.1 2.8 0.0076 15.9 0.5 2.8 3 1 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF4351 PF14261.6 KUM66714.1 - 0.28 11.3 1.1 1.1 9.3 1.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) DUF913 PF06025.12 KUM66714.1 - 0.53 9.2 3.9 3.2 6.6 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) YabP PF07873.11 KUM66716.1 - 0.18 11.6 0.0 0.55 10.1 0.0 1.7 1 0 0 1 1 1 0 YabP family RIO1 PF01163.22 KUM66717.1 - 1.1e-40 139.2 1.0 2.1e-29 102.5 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 KUM66717.1 - 2.1e-30 104.7 0.0 1e-29 102.6 0.0 2.0 2 0 0 2 2 2 1 Rio2, N-terminal Kdo PF06293.14 KUM66717.1 - 2.6e-07 30.2 0.0 1.3e-05 24.7 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KUM66717.1 - 6e-06 26.4 0.0 0.037 14.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_Ag35 PF03286.14 KUM66717.1 - 0.08 12.7 6.6 0.16 11.8 6.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SDA1 PF05285.12 KUM66717.1 - 0.97 8.8 13.5 2 7.8 13.5 1.5 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 KUM66717.1 - 5.5 6.2 12.8 8.7 5.6 12.8 1.2 1 0 0 1 1 1 0 NOA36 protein RPN1_RPN2_N PF17781.1 KUM66718.1 - 6.1e-116 387.1 0.9 8.6e-116 386.6 0.4 1.5 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KUM66718.1 - 6.6e-30 102.9 0.0 1.1e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KUM66718.1 - 3.1e-17 62.0 19.1 2.6e-05 24.4 0.2 7.8 7 1 0 7 7 7 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KUM66718.1 - 8.7e-05 22.8 0.8 1.3 9.4 0.0 4.1 3 2 0 3 3 3 2 HEAT repeats IFRD PF05004.13 KUM66718.1 - 0.15 11.2 1.3 2.4 7.2 0.3 3.0 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Lon_C PF05362.13 KUM66719.1 - 1e-69 234.2 0.3 2.9e-69 232.7 0.2 1.8 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KUM66719.1 - 2.5e-30 105.9 0.0 4.3e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KUM66719.1 - 4.6e-23 82.1 0.0 1.7e-22 80.3 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KUM66719.1 - 6.3e-08 32.7 0.0 1.8e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KUM66719.1 - 2.5e-07 30.6 0.0 2.2e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KUM66719.1 - 3.5e-06 27.5 0.6 1.3e-05 25.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 KUM66719.1 - 5.4e-05 23.1 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KUM66719.1 - 0.00015 21.1 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KUM66719.1 - 0.00027 21.2 0.2 0.0046 17.2 0.0 3.0 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 KUM66719.1 - 0.00047 19.9 0.1 0.0014 18.4 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KUM66719.1 - 0.00079 19.6 0.0 0.002 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KUM66719.1 - 0.0008 19.2 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KUM66719.1 - 0.0021 18.2 0.0 0.005 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KUM66719.1 - 0.015 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KUM66719.1 - 0.023 14.2 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 KUM66719.1 - 0.031 14.1 0.3 0.088 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KUM66719.1 - 0.036 14.6 0.0 0.09 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KUM66719.1 - 0.037 14.4 0.0 0.32 11.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 KUM66719.1 - 0.037 14.1 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KUM66719.1 - 0.047 13.6 0.0 2.1 8.2 0.0 2.8 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KUM66719.1 - 0.062 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KUM66719.1 - 0.065 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KUM66719.1 - 0.07 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_PrkA PF08298.11 KUM66719.1 - 0.086 11.7 0.0 0.53 9.2 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain AAA_30 PF13604.6 KUM66719.1 - 0.099 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KUM66719.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 KUM66719.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain TniB PF05621.11 KUM66719.1 - 0.14 11.6 0.0 0.51 9.7 0.0 1.9 1 0 0 1 1 1 0 Bacterial TniB protein AAA_19 PF13245.6 KUM66719.1 - 0.14 12.5 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain CCDC-167 PF15188.6 KUM66719.1 - 0.56 10.6 3.8 0.83 10.0 1.0 2.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 AAA_23 PF13476.6 KUM66719.1 - 0.66 10.5 0.0 0.66 10.5 0.0 3.0 2 1 0 2 2 1 0 AAA domain Ribosomal_L23 PF00276.20 KUM66720.1 - 3.3e-10 40.2 0.0 6.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 TAP42 PF04177.12 KUM66721.1 - 5.5e-78 262.3 0.4 6.1e-78 262.1 0.4 1.0 1 0 0 1 1 1 1 TAP42-like family Porphobil_deam PF01379.20 KUM66722.1 - 1.6e-71 240.0 0.0 2.3e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KUM66722.1 - 3.2e-17 62.7 0.3 7.8e-17 61.4 0.3 1.7 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Fibrinogen_aC PF12160.8 KUM66722.1 - 0.048 13.5 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Fibrinogen alpha C domain Ribonuclease_3 PF00636.26 KUM66723.1 - 6.5e-43 145.6 0.0 2.1e-20 73.3 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KUM66723.1 - 1.6e-26 93.0 0.1 2.3e-13 50.4 0.0 4.0 3 2 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KUM66723.1 - 2.7e-20 72.3 0.3 1.3e-19 70.1 0.1 2.4 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KUM66723.1 - 2.9e-16 59.8 0.1 8.6e-16 58.3 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KUM66723.1 - 8.4e-14 51.9 0.0 3.2e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KUM66723.1 - 1.4e-10 41.2 0.0 3.8e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 KUM66723.1 - 0.005 17.5 0.4 1.7 9.4 0.0 2.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif TAP42 PF04177.12 KUM66724.1 - 1.6e-15 57.0 0.4 1.8e-15 56.9 0.4 1.0 1 0 0 1 1 1 1 TAP42-like family DUF3450 PF11932.8 KUM66725.1 - 2.9 7.2 11.0 4.4 6.5 10.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Zn_clus PF00172.18 KUM66726.1 - 0.00027 21.0 9.4 0.00041 20.4 9.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NifU_N PF01592.16 KUM66728.1 - 1.6e-53 180.2 0.1 3.8e-53 179.0 0.1 1.6 2 0 0 2 2 2 1 NifU-like N terminal domain ABC1 PF03109.16 KUM66729.1 - 9.4e-34 116.1 0.1 1.6e-33 115.4 0.1 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 KUM66729.1 - 0.081 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Alpha_E3_glycop PF01563.16 KUM66729.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein RAP1 PF07218.11 KUM66729.1 - 0.68 8.1 6.2 0.99 7.6 6.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cu_amine_oxid PF01179.20 KUM66730.1 - 9.6e-156 518.8 0.0 1.2e-155 518.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KUM66730.1 - 2e-18 66.6 0.0 5.5e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KUM66730.1 - 8e-14 51.6 0.1 1.3e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF4105 PF13387.6 KUM66730.1 - 0.089 12.4 0.1 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4105) DHquinase_I PF01487.15 KUM66731.1 - 1.6e-47 162.7 0.0 2.2e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase DUF974 PF06159.13 KUM66732.1 - 9.4e-79 264.7 0.0 1.1e-78 264.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) PhaC_N PF07167.13 KUM66732.1 - 0.015 15.0 0.2 0.15 11.7 0.0 2.3 2 1 1 3 3 3 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus NAD_binding_8 PF13450.6 KUM66733.1 - 2.7e-17 62.8 0.0 7.5e-17 61.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KUM66733.1 - 3.6e-11 43.0 0.0 1.1e-06 28.2 0.0 3.1 2 1 0 3 3 3 3 Flavin containing amine oxidoreductase DAO PF01266.24 KUM66733.1 - 0.0014 18.3 0.0 0.0075 15.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KUM66733.1 - 0.0045 17.0 0.1 0.32 11.0 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KUM66733.1 - 0.0087 15.3 0.0 0.15 11.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KUM66733.1 - 0.014 14.5 0.0 0.068 12.2 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain DUF5529 PF17669.1 KUM66733.1 - 0.058 13.4 0.5 0.11 12.5 0.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5529) K_oxygenase PF13434.6 KUM66733.1 - 0.16 11.0 0.3 18 4.3 0.1 2.4 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KUM66733.1 - 0.2 12.3 0.1 0.58 10.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KUM66734.1 - 1.5e-31 109.7 33.7 1.5e-31 109.7 33.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Plasmodium_Vir PF05795.11 KUM66735.1 - 0.12 11.8 1.2 0.13 11.6 1.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Arfaptin PF06456.13 KUM66735.1 - 0.17 11.4 0.2 0.2 11.2 0.2 1.1 1 0 0 1 1 1 0 Arfaptin-like domain PRK PF00485.18 KUM66737.1 - 6.2e-05 22.8 0.0 9.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KUM66737.1 - 0.0018 17.5 0.0 0.0026 17.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KUM66737.1 - 0.056 13.8 0.0 0.098 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KUM66737.1 - 0.074 12.3 0.2 0.14 11.4 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 KUM66737.1 - 0.12 11.4 0.1 0.24 10.4 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 KUM66737.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KUM66737.1 - 0.18 12.3 0.3 0.61 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain FAA_hydrolase PF01557.18 KUM66739.1 - 1.9e-05 24.4 0.0 2.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family CiPC PF15800.5 KUM66739.1 - 0.075 12.7 5.2 0.079 12.7 5.2 1.1 1 0 0 1 1 1 0 Clock interacting protein circadian DPBB_1 PF03330.18 KUM66740.1 - 0.0009 19.5 0.0 0.0022 18.2 0.0 1.8 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KUM66740.1 - 0.0054 16.6 0.3 0.0054 16.6 0.3 1.8 2 0 0 2 2 2 1 Barwin family BPL_C PF02237.17 KUM66740.1 - 0.19 11.6 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Glyco_transf_25 PF01755.17 KUM66741.1 - 0.00034 20.6 0.0 0.00057 19.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Ribonuc_red_lgC PF02867.15 KUM66742.1 - 1.1e-183 611.6 0.0 1.5e-183 611.1 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KUM66742.1 - 5.3e-23 80.8 0.0 1.1e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KUM66742.1 - 4.7e-15 55.9 0.0 1.2e-14 54.7 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain Mur_ligase_M PF08245.12 KUM66743.1 - 1.2e-06 28.7 0.4 2.4e-06 27.7 0.4 1.5 1 1 0 1 1 1 1 Mur ligase middle domain Pkinase PF00069.25 KUM66744.1 - 1.1e-72 244.6 0.0 3.4e-72 243.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KUM66744.1 - 2.7e-50 171.1 0.0 5.6e-50 170.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KUM66744.1 - 0.0019 17.1 0.0 0.0038 16.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KUM66744.1 - 0.022 14.1 0.0 0.38 10.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Exo70 PF03081.15 KUM66744.1 - 1.2 8.1 4.5 4 6.4 0.5 2.8 3 0 0 3 3 3 0 Exo70 exocyst complex subunit Adaptin_N PF01602.20 KUM66744.1 - 3.2 6.2 8.0 18 3.7 5.8 2.7 2 1 0 2 2 2 0 Adaptin N terminal region 2-Hacid_dh_C PF02826.19 KUM66745.1 - 4.6e-45 153.2 0.0 7.2e-45 152.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KUM66745.1 - 0.00054 19.6 0.0 0.00088 18.9 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ELFV_dehydrog PF00208.21 KUM66745.1 - 0.00063 19.5 0.0 0.00093 19.0 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AdoHcyase_NAD PF00670.21 KUM66745.1 - 0.0089 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 KUM66745.1 - 0.01 16.4 0.0 0.025 15.1 0.0 1.6 2 0 0 2 2 2 1 XdhC Rossmann domain Pyr_redox PF00070.27 KUM66745.1 - 0.018 15.6 0.0 0.035 14.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KUM66745.1 - 0.18 12.3 0.0 0.34 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Fungal_trans PF04082.18 KUM66746.1 - 8.5e-20 70.9 0.0 1.4e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM66746.1 - 6.3e-05 23.0 17.4 6.3e-05 23.0 17.4 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_bind_2 PF04299.12 KUM66747.1 - 3.3e-49 166.8 0.0 5.1e-48 163.0 0.0 2.1 1 1 0 1 1 1 1 Putative FMN-binding domain DENN PF02141.21 KUM66748.1 - 3.9e-58 196.5 0.2 6.5e-58 195.7 0.2 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 KUM66748.1 - 4e-13 49.1 1.3 1e-12 47.9 0.4 2.3 3 0 0 3 3 3 1 dDENN domain uDENN PF03456.18 KUM66748.1 - 4.4e-13 49.8 0.0 1.3e-12 48.3 0.0 1.9 1 0 0 1 1 1 1 uDENN domain C1_1 PF00130.22 KUM66748.1 - 1e-05 25.3 6.3 1.8e-05 24.5 6.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KUM66748.1 - 1.3e-05 25.4 2.6 1.3e-05 25.4 2.6 1.7 2 0 0 2 2 2 1 C1 domain SPA PF08616.10 KUM66748.1 - 0.031 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis Zf_RING PF16744.5 KUM66748.1 - 0.11 12.7 4.8 0.24 11.5 4.8 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 KUM66748.1 - 0.4 10.3 6.1 0.8 9.4 6.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KUM66748.1 - 0.63 10.0 8.6 0.3 11.0 5.3 2.0 1 1 1 2 2 2 0 PHD-finger CENP-N PF05238.13 KUM66749.1 - 1.4e-141 472.6 0.0 1.6e-141 472.4 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.15 KUM66750.1 - 6.6e-14 51.7 9.0 6.6e-14 51.7 9.0 1.9 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KUM66750.1 - 0.00016 21.7 4.6 0.00034 20.7 4.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor DUF5343 PF17278.2 KUM66750.1 - 0.034 14.2 1.6 0.16 12.1 0.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5343) CBP_BcsG PF11658.8 KUM66750.1 - 0.17 10.3 2.2 0.3 9.4 2.2 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF5094 PF17015.5 KUM66750.1 - 0.5 10.5 5.3 0.85 9.7 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) DDRGK PF09756.9 KUM66750.1 - 1.9 8.0 16.4 0.13 11.9 11.4 1.4 2 0 0 2 2 2 0 DDRGK domain NAM-associated PF14303.6 KUM66750.1 - 8.9 7.0 14.7 2.6 8.7 10.7 1.9 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain TehB PF03848.14 KUM66753.1 - 0.16 11.3 0.1 0.32 10.4 0.1 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB HATPase_c_3 PF13589.6 KUM66755.1 - 1.6e-18 66.8 0.0 3.6e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KUM66755.1 - 1e-05 26.0 0.0 3e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KUM66755.1 - 4.7e-05 23.2 0.0 0.0021 17.9 0.0 3.1 2 1 0 2 2 2 1 MutL C terminal dimerisation domain p450 PF00067.22 KUM66757.1 - 1.2e-44 152.9 0.0 1.5e-44 152.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RasGEF PF00617.19 KUM66758.1 - 1.7e-50 171.7 1.2 3.8e-50 170.5 1.2 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KUM66758.1 - 1.3e-14 54.3 0.0 3.7e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 KUM66758.1 - 2.1e-06 27.5 0.0 4.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KUM66758.1 - 1.9e-05 24.2 0.0 3.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain ABC2_membrane PF01061.24 KUM66759.1 - 6.5e-76 254.4 49.0 3.9e-44 150.6 14.3 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KUM66759.1 - 7e-38 130.2 0.0 1.1e-17 64.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KUM66759.1 - 2.7e-30 104.1 7.7 2e-28 98.1 0.1 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KUM66759.1 - 5.9e-06 25.6 31.1 0.00096 18.4 11.1 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KUM66759.1 - 1.5e-05 25.5 0.1 0.019 15.4 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KUM66759.1 - 0.00018 21.1 0.1 0.0037 16.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KUM66759.1 - 0.00019 21.7 0.0 1.1 9.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KUM66759.1 - 0.00077 20.0 0.0 2.2 8.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KUM66759.1 - 0.00095 19.1 0.1 0.008 16.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KUM66759.1 - 0.0015 18.3 1.0 0.091 12.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KUM66759.1 - 0.0018 18.4 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KUM66759.1 - 0.0021 18.3 0.6 1 9.6 0.3 2.6 2 0 0 2 2 2 1 AAA domain ABC_trans_N PF14510.6 KUM66759.1 - 0.0028 18.2 0.0 0.0089 16.6 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal cobW PF02492.19 KUM66759.1 - 0.0043 16.7 0.7 1.3 8.6 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KUM66759.1 - 0.026 14.2 0.1 7.5 6.2 0.5 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KUM66759.1 - 0.055 13.4 0.6 3.6 7.5 0.2 2.3 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 KUM66759.1 - 0.12 12.1 1.0 9.2 6.0 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 KUM66759.1 - 0.15 11.3 0.1 4 6.7 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_21 PF13304.6 KUM66759.1 - 0.16 11.8 0.1 4 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KUM66759.1 - 0.16 11.9 0.0 19 5.1 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AA_permease_2 PF13520.6 KUM66760.1 - 7.4e-57 193.1 49.1 8.7e-57 192.8 49.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM66760.1 - 3.9e-21 75.2 37.5 5.4e-21 74.7 37.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1182 PF06681.13 KUM66760.1 - 0.12 11.9 7.8 0.13 11.8 4.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1182) Aldedh PF00171.22 KUM66761.1 - 6.5e-182 605.2 0.5 7.3e-182 605.0 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KUM66761.1 - 0.066 12.7 0.0 0.72 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Anp1 PF03452.14 KUM66763.1 - 1.6e-107 358.8 0.0 2e-107 358.5 0.0 1.1 1 0 0 1 1 1 1 Anp1 Beta-lactamase PF00144.24 KUM66764.1 - 2.2e-26 92.9 0.0 3.1e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase YCII PF03795.14 KUM66765.1 - 9.9e-11 41.9 0.0 1.2e-10 41.6 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain Ecm33 PF12454.8 KUM66766.1 - 9.7e-14 51.2 1.1 9.7e-14 51.2 1.1 2.7 2 1 1 3 3 3 1 GPI-anchored cell wall organization protein LRR_5 PF13306.6 KUM66766.1 - 3.1e-08 33.6 0.5 0.0021 18.0 0.9 2.9 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) Recep_L_domain PF01030.24 KUM66766.1 - 6.9e-06 26.2 1.6 0.13 12.4 0.0 4.7 1 1 3 4 4 4 1 Receptor L domain SR-25 PF10500.9 KUM66766.1 - 1.7 8.2 4.4 2.7 7.6 4.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ArsB PF02040.15 KUM66767.1 - 3.6e-09 36.5 24.1 6.3e-06 25.8 11.8 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein Sugar_tr PF00083.24 KUM66769.1 - 2.4e-86 290.4 23.0 2.8e-86 290.2 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM66769.1 - 2.9e-28 98.8 27.6 2.9e-28 98.8 27.6 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Sensor PF13796.6 KUM66769.1 - 0.0065 16.5 2.3 0.0065 16.5 2.3 3.3 2 1 1 3 3 3 1 Putative sensor DUF4271 PF14093.6 KUM66769.1 - 5.1 6.9 17.9 0.2 11.5 11.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) Pex24p PF06398.11 KUM66770.1 - 0.0039 16.2 1.5 0.043 12.8 0.0 2.1 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin Metallophos PF00149.28 KUM66771.1 - 5.3e-10 40.1 0.4 8.3e-10 39.5 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.16 KUM66772.1 - 9.4e-12 44.5 31.5 9.4e-12 44.5 31.5 2.9 2 2 1 3 3 3 2 Major Facilitator Superfamily ELFV_dehydrog PF00208.21 KUM66773.1 - 4.3e-83 278.8 5.4 5.4e-83 278.4 5.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KUM66773.1 - 1.7e-50 170.3 0.0 3.3e-50 169.3 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Med5 PF08689.10 KUM66774.1 - 5.2e-181 604.1 0.0 9.9e-181 603.1 0.0 1.4 1 1 0 1 1 1 1 Mediator complex subunit Med5 Ank_2 PF12796.7 KUM66775.1 - 3.6e-78 258.2 2.2 1.4e-10 41.6 0.0 14.9 8 4 6 15 15 15 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM66775.1 - 2.1e-58 194.0 15.3 3.2e-06 27.6 0.0 23.4 15 7 10 25 25 25 16 Ankyrin repeats (many copies) Ank PF00023.30 KUM66775.1 - 1.5e-41 139.1 33.4 0.0023 18.3 0.0 25.1 26 2 0 26 26 26 8 Ankyrin repeat Ank_3 PF13606.6 KUM66775.1 - 4e-40 131.2 13.2 0.00045 20.4 0.0 23.1 27 0 0 27 27 27 6 Ankyrin repeat Ank_5 PF13857.6 KUM66775.1 - 2.1e-33 113.9 38.6 0.011 16.1 0.0 21.2 17 5 4 22 22 22 10 Ankyrin repeats (many copies) NACHT PF05729.12 KUM66775.1 - 2.7e-08 33.9 0.2 1.9e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KUM66775.1 - 0.0033 17.8 0.0 0.016 15.6 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain Amidase PF01425.21 KUM66777.1 - 4.6e-71 240.1 0.3 7.8e-68 229.5 0.0 2.0 2 0 0 2 2 2 2 Amidase Pec_lyase_C PF00544.19 KUM66778.1 - 3.5e-18 66.0 11.4 3.6e-17 62.7 11.4 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KUM66778.1 - 5e-07 29.7 25.5 0.00011 22.1 3.8 2.3 1 1 1 2 2 2 2 Right handed beta helix region Ferritin_2 PF13668.6 KUM66779.1 - 7.5e-08 32.7 0.0 1.2e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Sugar_tr PF00083.24 KUM66780.1 - 3.9e-83 279.8 20.5 4.5e-83 279.6 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM66780.1 - 8.2e-32 110.5 44.1 5.6e-30 104.5 22.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KUM66780.1 - 3.8e-06 25.7 0.5 3.8e-06 25.7 0.5 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 KUM66780.1 - 6.7 4.9 12.3 0.035 12.4 0.3 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 KUM66781.1 - 6.2e-58 196.7 0.0 7.3e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fer2_3 PF13085.6 KUM66782.1 - 4e-32 110.5 0.0 6.5e-32 109.8 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KUM66782.1 - 2.7e-09 37.4 5.2 2.7e-09 37.4 5.2 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KUM66782.1 - 2.4e-07 30.8 3.1 2.4e-07 30.8 3.1 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KUM66782.1 - 3.8e-07 30.4 7.6 3.8e-07 30.4 7.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KUM66782.1 - 0.014 16.0 6.4 0.014 16.0 6.4 2.4 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer2 PF00111.27 KUM66782.1 - 0.017 15.1 0.7 0.017 15.1 0.7 2.2 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 KUM66782.1 - 1.6 8.9 12.9 4.5 7.5 9.8 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 KUM66782.1 - 5.6 7.2 8.0 1.4 9.2 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain NmrA PF05368.13 KUM66783.1 - 3.7e-13 49.6 0.0 5.1e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM66783.1 - 2.1e-08 34.3 0.0 3.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KUM66783.1 - 0.00023 21.1 0.0 0.0058 16.6 0.0 2.2 2 0 0 2 2 2 1 KR domain Semialdhyde_dh PF01118.24 KUM66783.1 - 0.18 12.3 0.1 1.1 9.7 0.0 2.2 1 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain PhyH PF05721.13 KUM66785.1 - 0.0016 18.8 0.1 0.0041 17.4 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.16 KUM66786.1 - 6e-26 91.2 62.6 1.5e-22 80.0 19.0 3.3 2 1 2 4 4 4 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM66786.1 - 1e-09 37.8 9.6 1e-09 37.8 9.6 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter zf-LITAF-like PF10601.9 KUM66788.1 - 0.00044 20.4 0.8 0.0007 19.8 0.8 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-CHCC PF10276.9 KUM66788.1 - 1.4 9.1 4.7 30 4.8 0.1 2.4 1 1 1 2 2 2 0 Zinc-finger domain KAR9 PF08580.10 KUM66788.1 - 1.5 7.3 12.1 1.6 7.2 12.1 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 F-box-like PF12937.7 KUM66790.1 - 5.1e-06 26.3 0.0 1.3e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like zf-CCCH PF00642.24 KUM66791.1 - 1.2e-06 28.3 8.5 4.5e-05 23.3 1.1 3.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KUM66791.1 - 1.3e-05 24.8 2.4 1.3e-05 24.8 2.4 4.2 5 0 0 5 5 5 1 CCCH-type zinc finger Torus PF16131.5 KUM66791.1 - 3.7e-05 24.4 0.9 0.00011 22.9 0.9 1.8 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 KUM66791.1 - 0.0045 17.0 5.2 0.0045 17.0 5.2 3.2 3 0 0 3 3 3 1 Zinc finger domain Dynactin_p22 PF07426.11 KUM66791.1 - 0.031 14.2 0.5 0.08 12.8 0.4 1.7 2 0 0 2 2 2 0 Dynactin subunit p22 SKA2 PF16740.5 KUM66791.1 - 0.081 12.7 1.5 0.11 12.3 0.3 1.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 KELK PF15796.5 KUM66791.1 - 0.16 12.4 2.5 0.3 11.5 2.5 1.4 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Nup88 PF10168.9 KUM66791.1 - 0.34 8.7 0.6 0.54 8.0 0.6 1.2 1 0 0 1 1 1 0 Nuclear pore component Glyco_hydro_76 PF03663.14 KUM66792.1 - 3.7e-46 158.3 11.0 5.3e-46 157.8 11.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KUM66792.1 - 0.00031 19.9 0.6 0.04 13.0 0.0 2.3 1 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 GST_N PF02798.20 KUM66794.1 - 1.5e-10 41.2 0.0 2.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KUM66794.1 - 2e-07 31.2 0.0 4.5e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KUM66794.1 - 9.4e-07 29.2 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KUM66794.1 - 1.2e-05 25.4 0.0 2.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KUM66794.1 - 0.0017 18.3 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KUM66794.1 - 0.022 14.9 0.0 0.034 14.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BetaGal_dom3 PF13363.6 KUM66795.1 - 5.9e-19 67.4 0.2 1e-18 66.7 0.2 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 BetaGal_dom2 PF10435.9 KUM66795.1 - 2.4e-17 63.3 0.0 3.6e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KUM66795.1 - 9e-14 52.0 1.3 9.2e-12 45.5 1.3 2.4 1 1 0 1 1 1 1 Beta-galactosidase jelly roll domain KRAB PF01352.27 KUM66796.1 - 0.019 14.6 0.8 0.06 13.0 0.8 1.9 1 0 0 1 1 1 0 KRAB box RrnaAD PF00398.20 KUM66798.1 - 0.014 14.4 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PNP_phzG_C PF10590.9 KUM66801.1 - 2.2e-20 72.4 6.7 4.7e-20 71.4 4.2 2.7 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KUM66801.1 - 8.8e-07 29.0 0.3 0.0018 18.4 0.0 2.9 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase PPR_2 PF13041.6 KUM66802.1 - 2.6e-43 146.0 5.4 2.3e-09 37.3 0.0 12.2 10 3 4 14 14 14 6 PPR repeat family PPR_3 PF13812.6 KUM66802.1 - 3.3e-30 104.0 2.1 0.0027 17.7 0.0 11.2 7 4 6 13 13 13 10 Pentatricopeptide repeat domain PPR PF01535.20 KUM66802.1 - 2.2e-25 87.1 17.9 0.0011 19.0 0.0 13.2 14 2 0 14 14 14 6 PPR repeat PPR_1 PF12854.7 KUM66802.1 - 5.4e-20 70.8 1.7 1.7e-05 24.4 0.1 10.1 11 0 0 11 11 11 3 PPR repeat PPR_long PF17177.4 KUM66802.1 - 9e-19 67.7 16.4 2e-09 37.2 0.1 7.2 5 1 0 6 6 6 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 KUM66802.1 - 3.7e-06 27.4 0.1 0.0031 17.9 0.0 4.6 5 1 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_19 PF14559.6 KUM66802.1 - 0.0019 18.7 11.5 3.4 8.2 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KUM66802.1 - 0.3 11.2 2.4 4.2 7.6 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat FAD_binding_3 PF01494.19 KUM66803.1 - 1.4e-15 57.4 0.0 2.7e-15 56.5 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KUM66803.1 - 9.7e-07 28.9 0.1 2.5e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KUM66803.1 - 9.9e-07 28.2 0.5 1.7e-06 27.4 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KUM66803.1 - 3e-05 23.6 0.8 5.2e-05 22.8 0.5 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM66803.1 - 6.3e-05 22.3 0.1 0.00025 20.4 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KUM66803.1 - 0.00019 21.2 3.4 0.0047 16.6 2.3 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KUM66803.1 - 0.001 17.9 0.4 0.0015 17.3 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KUM66803.1 - 0.001 19.6 1.2 0.0026 18.3 1.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM66803.1 - 0.001 18.4 1.4 0.0017 17.7 1.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KUM66803.1 - 0.0015 17.7 0.3 0.0024 17.0 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KUM66803.1 - 0.0032 16.6 0.2 0.14 11.1 0.6 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KUM66803.1 - 0.022 14.0 0.4 0.045 13.0 0.4 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KUM66803.1 - 0.055 12.7 0.2 0.093 12.0 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KUM66803.1 - 0.081 11.8 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_11 PF14833.6 KUM66805.1 - 3.9e-38 130.4 2.7 2.6e-29 102.0 0.0 2.3 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KUM66805.1 - 1e-34 120.0 0.0 2.5e-34 118.7 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KUM66805.1 - 0.00013 22.4 0.1 0.00074 20.0 0.0 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KUM66805.1 - 0.00031 20.7 0.0 0.0007 19.5 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KUM66805.1 - 0.015 14.6 0.0 0.037 13.4 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RGS PF00615.19 KUM66806.1 - 0.00058 20.1 0.0 0.0013 19.0 0.0 1.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain Mito_morph_reg PF14972.6 KUM66806.1 - 0.75 9.4 2.7 1.2 8.7 1.4 1.9 2 0 0 2 2 2 0 Mitochondrial morphogenesis regulator Ank_2 PF12796.7 KUM66809.1 - 1.3e-48 163.5 2.9 3e-14 53.4 0.2 4.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM66809.1 - 3.2e-28 97.7 0.1 1.6e-08 34.9 0.0 5.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KUM66809.1 - 1.1e-27 95.2 0.2 0.0001 22.6 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KUM66809.1 - 1.5e-25 86.4 0.0 0.011 16.2 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KUM66809.1 - 3.3e-23 81.4 5.4 6.1e-07 29.6 0.1 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) MFS_1 PF07690.16 KUM66811.1 - 5.3e-41 140.7 56.4 1.6e-33 116.1 37.3 3.5 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM66811.1 - 5.3e-15 54.9 22.3 1.5e-14 53.4 22.3 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 KUM66811.1 - 0.03 14.6 0.9 0.03 14.6 0.9 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) HCV_NS4a PF01006.20 KUM66811.1 - 3.6 7.4 6.7 2 8.2 3.9 2.1 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a Lactamase_B PF00753.27 KUM66812.1 - 7.2e-14 52.3 0.4 1.4e-13 51.3 0.4 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_hydro_cc PF11790.8 KUM66813.1 - 3e-12 46.6 0.0 3.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Ysc84 PF04366.12 KUM66814.1 - 1.6e-37 128.1 0.2 2.6e-37 127.4 0.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Acetyltransf_1 PF00583.25 KUM66815.1 - 1e-11 45.1 0.0 1.3e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KUM66815.1 - 2.6e-11 43.8 0.0 4.4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KUM66815.1 - 2.8e-11 43.5 0.0 3.3e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KUM66815.1 - 3.5e-06 27.1 0.0 1e-05 25.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KUM66815.1 - 0.00051 20.1 0.0 0.00083 19.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KUM66815.1 - 0.03 14.3 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein PanZ PF12568.8 KUM66815.1 - 0.091 12.5 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ F_bP_aldolase PF01116.20 KUM66817.1 - 3.5e-83 279.3 0.1 3.9e-83 279.2 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Beta-lactamase PF00144.24 KUM66819.1 - 1.2e-60 205.5 0.0 1.4e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Podoplanin PF05808.11 KUM66820.1 - 5.6e-05 23.3 6.2 0.00011 22.4 6.2 1.4 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 KUM66820.1 - 0.00012 22.0 1.3 0.00022 21.2 1.3 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF4690 PF15756.5 KUM66820.1 - 0.00024 21.6 4.0 0.00024 21.6 4.0 1.9 2 0 0 2 2 1 1 Small Novel Rich in Cartilage BatD PF13584.6 KUM66820.1 - 0.0016 17.3 0.1 0.0023 16.8 0.1 1.1 1 0 0 1 1 1 1 Oxygen tolerance SKG6 PF08693.10 KUM66820.1 - 0.0045 16.4 5.2 0.018 14.4 5.2 2.1 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4064 PF13273.6 KUM66820.1 - 0.0046 17.2 1.4 0.0089 16.3 1.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4064) Glycophorin_A PF01102.18 KUM66820.1 - 0.0061 16.8 4.9 0.0093 16.2 4.5 1.4 1 1 0 1 1 1 1 Glycophorin A RIFIN PF02009.16 KUM66820.1 - 0.012 15.6 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Rifin DUF5305 PF17231.2 KUM66820.1 - 0.013 14.9 1.7 0.022 14.2 1.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) BUD22 PF09073.10 KUM66820.1 - 0.015 14.7 3.1 0.02 14.3 3.1 1.2 1 0 0 1 1 1 0 BUD22 EphA2_TM PF14575.6 KUM66820.1 - 0.016 16.0 0.0 0.037 14.9 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KUM66820.1 - 0.019 14.9 0.6 0.035 14.0 0.6 1.4 1 0 0 1 1 1 0 Syndecan domain Sporozoite_P67 PF05642.11 KUM66820.1 - 0.036 12.2 9.7 0.05 11.7 9.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Adeno_E3_CR2 PF02439.15 KUM66820.1 - 0.047 13.4 0.8 0.1 12.4 0.8 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TrbL PF04610.14 KUM66820.1 - 0.067 12.9 4.3 0.1 12.4 4.3 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein MGC-24 PF05283.11 KUM66820.1 - 0.074 13.5 9.8 0.03 14.8 7.2 1.7 2 0 0 2 2 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AJAP1_PANP_C PF15298.6 KUM66820.1 - 0.083 13.1 7.6 0.13 12.5 7.6 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF4366 PF14283.6 KUM66820.1 - 0.14 12.2 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Amnionless PF14828.6 KUM66820.1 - 0.15 10.9 3.0 0.22 10.3 2.7 1.3 1 1 0 1 1 1 0 Amnionless DAP10 PF07213.11 KUM66820.1 - 0.16 11.9 1.6 0.47 10.4 1.6 1.7 1 0 0 1 1 1 0 DAP10 membrane protein Sec10 PF07393.11 KUM66820.1 - 0.17 10.2 1.1 0.19 10.1 1.1 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 Stevor PF17410.2 KUM66820.1 - 0.19 11.3 0.2 0.27 10.7 0.2 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF2681 PF10883.8 KUM66820.1 - 0.19 12.1 0.3 0.36 11.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF1180 PF06679.12 KUM66820.1 - 0.25 11.7 11.4 0.028 14.9 6.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Macoilin PF09726.9 KUM66820.1 - 0.3 9.6 3.5 0.34 9.4 3.5 1.1 1 0 0 1 1 1 0 Macoilin family VSP PF03302.13 KUM66820.1 - 0.31 9.9 14.2 0.19 10.6 12.2 1.7 1 1 1 2 2 2 0 Giardia variant-specific surface protein CYYR1 PF10873.8 KUM66820.1 - 0.57 10.6 6.1 0.56 10.6 4.3 1.8 1 1 0 2 2 1 0 Cysteine and tyrosine-rich protein 1 Gram_pos_anchor PF00746.21 KUM66820.1 - 0.58 10.1 2.8 1.5 8.8 2.1 2.0 1 1 1 2 2 2 0 LPXTG cell wall anchor motif DUF5423 PF17461.2 KUM66820.1 - 0.71 8.7 15.8 0.082 11.8 11.3 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5423) HCMV_UL124 PF17609.2 KUM66820.1 - 3.8 7.7 15.2 8.5 6.6 15.2 1.5 1 0 0 1 1 1 0 Family of unknown function Xan_ur_permease PF00860.20 KUM66822.1 - 8.6e-24 83.9 34.2 5.5e-23 81.3 32.0 2.5 2 1 0 2 2 2 1 Permease family MFS_1 PF07690.16 KUM66823.1 - 9.1e-38 130.1 45.8 9.1e-38 130.1 45.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM66823.1 - 2.5e-08 33.3 16.1 2.5e-08 33.3 16.1 2.4 2 2 0 2 2 2 1 Sugar (and other) transporter ArAE_2_N PF10337.9 KUM66824.1 - 3.9e-65 220.7 20.7 5e-51 174.2 0.3 4.3 2 2 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KUM66824.1 - 2.8e-17 63.0 15.4 2.8e-17 63.0 15.4 3.0 2 2 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KUM66824.1 - 2.7e-13 50.3 0.0 1.2e-12 48.1 0.0 2.1 2 1 0 2 2 2 1 Aromatic acid exporter family member 2 DUF5315 PF17242.2 KUM66824.1 - 0.021 14.6 0.2 0.041 13.7 0.2 1.4 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) adh_short PF00106.25 KUM66825.1 - 4.6e-28 98.0 1.8 5.2e-19 68.5 1.3 2.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KUM66825.1 - 4.3e-26 91.9 1.5 3.9e-17 62.6 0.4 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM66825.1 - 5e-06 26.5 0.2 7.1e-06 26.1 0.2 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KUM66825.1 - 0.096 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KUM66826.1 - 4.6e-128 427.9 22.7 5.3e-128 427.7 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM66826.1 - 1.4e-25 90.0 35.8 7.4e-22 77.7 15.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ThiF PF00899.21 KUM66827.1 - 3.8e-60 203.3 0.0 5.5e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KUM66827.1 - 9.9e-07 29.3 0.0 4e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 KUM66827.1 - 0.017 15.2 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KUM66827.1 - 0.028 14.8 0.0 0.066 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Cation_ATPase_C PF00689.21 KUM66828.1 - 7.3 6.3 15.9 0.88 9.3 1.5 2.6 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus She9_MDM33 PF05546.11 KUM66829.1 - 1.5e-87 292.5 9.6 2.5e-87 291.8 9.6 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.20 KUM66829.1 - 0.047 13.4 1.1 0.094 12.5 1.1 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Rieske PF00355.26 KUM66830.1 - 9.7e-11 41.5 0.0 1.9e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KUM66830.1 - 1.4e-10 41.5 0.3 3e-10 40.4 0.3 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region GST_N_2 PF13409.6 KUM66831.1 - 4.5e-15 55.7 0.0 7.8e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KUM66831.1 - 1.2e-14 54.5 0.0 2.2e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KUM66831.1 - 2.3e-14 53.5 0.0 4.1e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KUM66831.1 - 5.9e-06 26.8 0.0 1e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KUM66831.1 - 8e-06 26.0 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 KUM66831.1 - 0.001 19.1 0.1 0.0019 18.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SH3_9 PF14604.6 KUM66832.1 - 1.8e-05 24.5 0.1 3.4e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KUM66832.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 SH3 domain EphA2_TM PF14575.6 KUM66832.1 - 0.056 14.3 0.0 0.29 12.0 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4690 PF15756.5 KUM66832.1 - 0.07 13.7 2.7 0.072 13.7 0.2 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage CYYR1 PF10873.8 KUM66832.1 - 4.4 7.7 12.0 0.45 11.0 6.2 2.4 2 1 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 DUF3180 PF11377.8 KUM66833.1 - 0.061 13.5 4.1 0.4 10.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) Vma12 PF11712.8 KUM66833.1 - 1.8 8.6 3.5 19 5.3 1.4 2.5 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ATP-synt_ab PF00006.25 KUM66835.1 - 3e-62 210.0 0.0 8e-62 208.7 0.0 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KUM66835.1 - 8.4e-23 80.7 2.8 3.4e-22 78.7 1.8 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 KUM66835.1 - 0.0075 15.6 0.2 0.013 14.8 0.2 1.4 1 0 0 1 1 1 1 KaiC AAA PF00004.29 KUM66835.1 - 0.017 15.6 0.0 1.2 9.6 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KUM66835.1 - 0.018 14.3 0.3 0.098 11.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 KUM66835.1 - 0.034 14.5 0.8 0.44 10.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KUM66835.1 - 0.044 13.7 0.3 0.096 12.6 0.1 1.6 2 0 0 2 2 2 0 RsgA GTPase ATPase_2 PF01637.18 KUM66835.1 - 0.053 13.4 0.0 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KUM66835.1 - 0.054 13.4 0.2 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 NACHT domain T3SS_ATPase_C PF18269.1 KUM66835.1 - 0.056 13.3 0.9 0.21 11.4 0.9 1.9 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain RNA_helicase PF00910.22 KUM66835.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF4618 PF15397.6 KUM66835.1 - 0.2 11.1 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Alpha-amylase_C PF02806.18 KUM66836.1 - 4.4e-23 81.6 0.0 9.9e-23 80.4 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KUM66836.1 - 4.2e-19 68.7 0.1 1.2e-18 67.2 0.1 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KUM66836.1 - 7.7e-16 58.6 0.0 8e-12 45.4 0.1 2.7 2 1 1 3 3 3 2 Alpha amylase, catalytic domain Cofilin_ADF PF00241.20 KUM66837.1 - 2.9e-35 120.7 0.5 3.3e-35 120.5 0.5 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein COX4 PF02936.14 KUM66838.1 - 2.8e-46 157.0 0.2 3.6e-46 156.6 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 KUM66838.1 - 0.015 15.7 0.4 0.032 14.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) zf-MYND PF01753.18 KUM66839.1 - 1.1e-08 35.0 6.1 1.9e-08 34.3 6.1 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KUM66839.1 - 0.0028 17.7 1.2 0.0067 16.5 1.2 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Fungal_lectin PF07938.12 KUM66840.1 - 4e-57 193.9 0.1 4.4e-57 193.8 0.1 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin Aldo_ket_red PF00248.21 KUM66841.1 - 1.3e-21 77.1 0.0 1.5e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KUM66842.1 - 4.8e-34 117.9 0.0 5.6e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Git3 PF11710.8 KUM66844.1 - 1.2e-33 116.6 14.5 2.9e-33 115.3 14.5 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KUM66844.1 - 6.3e-13 48.6 0.7 1.7e-12 47.2 0.0 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 KUM66844.1 - 4e-05 22.9 15.5 4.4e-05 22.8 14.8 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor OapA_N PF08525.11 KUM66844.1 - 0.089 12.8 0.1 0.089 12.8 0.1 2.3 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif Fungal_lectin PF07938.12 KUM66845.1 - 2.2e-69 234.1 0.2 2.4e-69 234.0 0.2 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin DUF4388 PF14332.6 KUM66845.1 - 0.05 13.9 0.0 1.8 8.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4388) YXWGXW PF12779.7 KUM66845.1 - 9 6.6 7.8 0.82 9.9 1.0 2.5 3 0 0 3 3 3 0 YXWGXW repeat (2 copies) Amidohydro_2 PF04909.14 KUM66846.1 - 6.5e-28 98.3 0.0 7.5e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase CBFD_NFYB_HMF PF00808.23 KUM66847.1 - 4.2e-15 55.8 2.2 5e-15 55.5 0.5 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KUM66847.1 - 0.00067 20.0 0.2 0.00067 20.0 0.2 1.8 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Pol_alpha_B_N PF08418.10 KUM66847.1 - 0.027 14.4 0.9 0.031 14.2 0.9 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Voltage_CLC PF00654.20 KUM66848.1 - 5.3e-88 295.6 30.1 5.3e-88 295.6 30.1 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KUM66848.1 - 9.9e-13 48.3 0.0 2.5e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain Pmp3 PF01679.17 KUM66849.1 - 1.3e-12 47.7 12.9 4.2e-11 42.9 4.7 2.1 2 0 0 2 2 2 2 Proteolipid membrane potential modulator TMEM52 PF14979.6 KUM66849.1 - 0.037 14.0 0.2 0.07 13.1 0.2 1.4 1 0 0 1 1 1 0 Transmembrane 52 ABC_tran PF00005.27 KUM66850.1 - 2.1e-37 128.7 0.0 2.1e-18 67.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KUM66850.1 - 1.2e-29 103.8 24.2 3.9e-21 75.9 14.0 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 KUM66850.1 - 1e-06 28.8 1.4 0.07 12.9 0.0 3.4 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KUM66850.1 - 1e-05 25.2 0.8 0.15 11.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KUM66850.1 - 3.3e-05 24.5 0.4 0.22 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KUM66850.1 - 4.9e-05 23.6 0.2 0.73 10.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 KUM66850.1 - 6.1e-05 22.6 4.1 0.65 9.4 0.1 4.3 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KUM66850.1 - 6.5e-05 22.9 0.4 0.51 10.2 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KUM66850.1 - 0.00021 21.4 0.0 0.61 10.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 KUM66850.1 - 0.00074 19.3 0.1 0.66 9.6 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 KUM66850.1 - 0.0034 17.4 0.0 0.43 10.6 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_18 PF13238.6 KUM66850.1 - 0.005 17.4 0.0 1.3 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KUM66850.1 - 0.012 16.0 0.1 7.8 6.9 0.1 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KUM66850.1 - 0.021 15.0 0.0 0.47 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KUM66850.1 - 0.068 12.7 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 KUM66850.1 - 0.096 12.8 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain DEAD PF00270.29 KUM66850.1 - 0.12 12.1 0.0 2.5 7.9 0.0 2.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase COX2-transmemb PF09125.10 KUM66850.1 - 0.23 11.3 1.3 0.79 9.6 0.6 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane GPI-anchored PF10342.9 KUM66851.1 - 1e-16 61.4 0.4 1e-16 61.4 0.4 3.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Macoilin PF09726.9 KUM66851.1 - 6.8 5.1 5.9 9.2 4.7 5.9 1.2 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 KUM66851.1 - 7 6.5 11.0 8.8 6.2 11.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 KUM66851.1 - 8.6 5.4 22.5 11 5.1 22.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein CBF PF03914.17 KUM66852.1 - 3.1e-37 128.2 1.8 8.4e-37 126.8 0.2 2.4 3 0 0 3 3 3 1 CBF/Mak21 family DPPIV_rep PF18811.1 KUM66852.1 - 0.092 12.7 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) low complexity region MFS_1 PF07690.16 KUM66853.1 - 1.9e-26 92.8 45.3 3.6e-15 55.8 18.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KUM66853.1 - 0.00013 20.6 4.5 0.0002 19.9 4.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UCR_Fe-S_N PF10399.9 KUM66853.1 - 0.24 10.8 5.6 14 5.1 0.0 3.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Phage_holin_2_4 PF16082.5 KUM66853.1 - 0.64 9.8 3.4 5.7 6.8 0.1 2.9 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like NAD_binding_10 PF13460.6 KUM66854.1 - 0.005 16.7 0.0 0.0061 16.5 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KUM66854.1 - 0.0091 15.0 0.0 0.04 12.9 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sugar_tr PF00083.24 KUM66855.1 - 3.9e-73 246.8 22.4 4.8e-73 246.6 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM66855.1 - 5.9e-19 68.2 38.5 6.7e-15 54.9 29.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.13 KUM66855.1 - 0.73 10.1 0.0 0.73 10.1 0.0 4.1 4 0 0 4 4 4 0 Transglycosylase associated protein Mt_ATP-synt_B PF05405.14 KUM66856.1 - 3.6e-18 65.7 0.0 5.4e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Sel1 PF08238.12 KUM66857.1 - 2.1e-17 63.2 4.3 3.3e-05 24.4 1.1 4.2 5 0 0 5 5 5 3 Sel1 repeat zf-LITAF-like PF10601.9 KUM66858.1 - 0.0074 16.5 0.9 0.01 16.1 0.9 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain ATP_transf PF09830.9 KUM66859.1 - 1.1e-21 76.7 0.0 2.4e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase zf-C2H2 PF00096.26 KUM66860.1 - 0.00032 21.0 18.8 0.46 11.0 1.1 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type BssC_TutF PF08201.11 KUM66860.1 - 0.075 13.0 0.4 0.27 11.2 0.4 2.0 1 0 0 1 1 1 0 BssC/TutF protein FOXP-CC PF16159.5 KUM66860.1 - 0.62 10.7 3.7 18 6.1 0.5 3.3 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KUM66860.1 - 1.2 10.1 20.5 0.69 10.9 0.7 4.9 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KUM66860.1 - 5.3 7.4 7.3 19 5.7 0.6 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PAF-AH_p_II PF03403.13 KUM66861.1 - 5.5e-15 54.8 0.0 6.3e-07 28.2 0.1 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KUM66861.1 - 2.3e-05 23.5 0.0 3.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KUM66861.1 - 0.00015 21.1 0.1 0.019 14.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Fungal_trans_2 PF11951.8 KUM66862.1 - 2.6e-14 52.8 2.4 9.4e-14 51.0 2.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM66862.1 - 2.3e-06 27.6 6.5 4.1e-06 26.8 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM72 PF16054.5 KUM66862.1 - 0.016 14.9 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein family 72 LOR PF04525.12 KUM66863.1 - 1.3e-23 83.6 0.0 1.5e-23 83.4 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related Ntox28 PF15605.6 KUM66863.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial toxin 28 Kdo PF06293.14 KUM66864.1 - 2.8e-05 23.6 0.0 3.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KUM66864.1 - 0.00032 20.1 0.0 0.00035 20.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain FAD_binding_3 PF01494.19 KUM66865.1 - 4.7e-22 78.7 0.1 1e-21 77.6 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Cbl_N2 PF02761.14 KUM66865.1 - 0.15 12.8 0.1 0.68 10.7 0.1 2.0 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain Alpha-amylase PF00128.24 KUM66866.1 - 1.8e-58 198.7 0.5 1.1e-56 192.8 0.5 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KUM66866.1 - 0.0098 16.2 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Tmemb_14 PF03647.13 KUM66867.1 - 4.2e-23 81.9 4.2 4.8e-23 81.7 4.2 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF543 PF04418.12 KUM66867.1 - 0.59 10.2 2.8 0.7 9.9 1.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF543) DUF3176 PF11374.8 KUM66868.1 - 5.7e-34 116.5 1.8 1.2e-33 115.5 1.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) LapA_dom PF06305.11 KUM66869.1 - 0.071 12.9 7.5 0.15 11.9 2.9 2.8 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 KUM66869.1 - 0.75 8.6 17.1 0.43 9.4 9.0 2.5 1 1 1 2 2 2 0 Major Facilitator Superfamily Tad PF13400.6 KUM66869.1 - 0.96 9.8 10.5 0.25 11.7 2.7 3.0 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like TspO_MBR PF03073.15 KUM66869.1 - 1.9 8.5 14.1 0.27 11.3 5.0 2.5 2 1 0 2 2 2 0 TspO/MBR family PAP2 PF01569.21 KUM66869.1 - 2.5 7.9 11.2 1.8 8.3 0.9 2.6 2 1 0 2 2 2 0 PAP2 superfamily TRI5 PF06330.11 KUM66870.1 - 5.3e-140 466.4 0.7 6.4e-140 466.1 0.7 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) SPC25 PF06703.11 KUM66871.1 - 7e-51 172.2 0.1 8e-51 172.0 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Synaptobrevin PF00957.21 KUM66872.1 - 5.9 6.8 5.9 33 4.4 3.9 2.3 2 0 0 2 2 2 0 Synaptobrevin Cys_Met_Meta_PP PF01053.20 KUM66873.1 - 3.8e-05 22.4 0.0 4e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MMS19_C PF12460.8 KUM66874.1 - 2.7e-124 415.5 20.7 2.4e-123 412.4 9.5 4.0 2 1 1 3 3 3 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 KUM66874.1 - 1.3e-94 316.6 0.8 1.3e-92 310.1 0.0 3.5 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 KUM66874.1 - 1.4e-06 28.5 5.9 0.017 15.3 0.0 4.9 5 1 0 6 6 6 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 KUM66874.1 - 1.9e-05 25.0 8.6 1.1 9.7 0.4 6.4 7 0 0 7 7 7 2 HEAT repeats WAPL PF07814.13 KUM66874.1 - 0.0078 15.0 2.5 0.014 14.2 0.4 2.3 1 1 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin HEAT_EZ PF13513.6 KUM66874.1 - 0.011 16.2 15.3 3.3 8.3 2.2 5.5 5 0 0 5 5 5 0 HEAT-like repeat HEAT PF02985.22 KUM66874.1 - 0.065 13.5 15.5 52 4.5 0.3 7.8 9 0 0 9 9 9 0 HEAT repeat Arm PF00514.23 KUM66874.1 - 0.071 13.2 5.2 1.4 9.0 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 KUM66874.1 - 0.11 11.7 4.8 0.32 10.2 0.3 3.7 4 1 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain Fasciclin PF02469.22 KUM66875.1 - 5e-07 30.0 0.0 8.8e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain EMC3_TMCO1 PF01956.16 KUM66876.1 - 3.6e-53 179.8 1.4 4.7e-53 179.4 1.4 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF4405 PF14358.6 KUM66876.1 - 3 8.5 6.6 8.7 7.0 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) SHE3 PF17078.5 KUM66878.1 - 8.9e-06 25.6 33.0 0.00046 20.0 24.6 2.3 1 1 2 3 3 3 3 SWI5-dependent HO expression protein 3 ADIP PF11559.8 KUM66878.1 - 0.00099 19.2 16.4 0.00099 19.2 16.4 3.2 1 1 3 4 4 4 2 Afadin- and alpha -actinin-Binding ZapB PF06005.12 KUM66878.1 - 0.0025 18.2 6.7 0.0025 18.2 6.7 3.8 1 1 2 3 3 3 1 Cell division protein ZapB Tup_N PF08581.10 KUM66878.1 - 0.031 14.6 2.1 0.031 14.6 2.1 3.5 2 2 1 3 3 3 0 Tup N-terminal HALZ PF02183.18 KUM66878.1 - 0.076 13.2 0.9 0.076 13.2 0.9 3.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper Vac_Fusion PF02346.16 KUM66878.1 - 0.14 11.8 5.7 0.62 9.7 0.0 3.9 3 1 1 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 DUF3037 PF11236.8 KUM66878.1 - 3.2 8.2 9.8 1.3 9.5 0.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) DXP_reductoisom PF02670.16 KUM66878.1 - 5.8 7.6 8.1 1.7 9.4 0.9 2.7 2 1 1 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase TPR_MLP1_2 PF07926.12 KUM66878.1 - 6.6 6.8 36.7 0.25 11.4 23.6 2.5 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Ank_4 PF13637.6 KUM66880.1 - 2.4e-48 161.9 6.6 1.8e-11 44.3 0.0 7.8 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KUM66880.1 - 2.2e-43 146.7 13.8 7.3e-18 64.9 0.2 5.0 4 2 1 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.30 KUM66880.1 - 2.6e-24 84.5 21.3 0.0012 19.2 0.0 9.6 10 2 1 11 11 11 6 Ankyrin repeat Ank_3 PF13606.6 KUM66880.1 - 8.4e-24 81.1 6.1 0.0045 17.4 0.0 9.8 10 1 1 11 11 11 5 Ankyrin repeat Ank_5 PF13857.6 KUM66880.1 - 5.8e-16 58.3 19.6 0.0082 16.4 0.1 8.1 3 1 6 9 9 9 7 Ankyrin repeats (many copies) NACHT PF05729.12 KUM66880.1 - 1.7e-09 37.8 0.1 3.4e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KUM66880.1 - 5.4e-06 26.7 0.1 1.4e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KUM66880.1 - 0.00014 22.3 0.2 0.00072 20.0 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KUM66880.1 - 0.082 12.1 0.0 0.18 10.9 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Pentapeptide_4 PF13599.6 KUM66881.1 - 0.076 13.2 0.7 59 3.9 0.1 3.1 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) RbpA PF13397.6 KUM66881.1 - 0.44 11.2 1.1 47 4.7 0.0 2.9 2 1 1 3 3 3 0 RNA polymerase-binding protein AA_permease_2 PF13520.6 KUM66883.1 - 1.9e-39 135.7 50.5 2.4e-39 135.4 50.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KUM66883.1 - 3.4e-26 91.9 46.1 4.4e-26 91.5 46.1 1.0 1 0 0 1 1 1 1 Amino acid permease HrpB2 PF09487.10 KUM66884.1 - 0.049 14.1 0.0 0.06 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) FAD_binding_4 PF01565.23 KUM66885.1 - 5.5e-10 39.1 4.0 1.1e-09 38.1 4.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KUM66885.1 - 2.1e-09 37.3 0.0 3.7e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like DUF3445 PF11927.8 KUM66886.1 - 1.4e-76 257.1 0.0 1.6e-76 256.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) TPR_2 PF07719.17 KUM66887.1 - 2.7e-22 77.0 2.9 1.6e-07 30.9 0.1 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KUM66887.1 - 2.9e-22 77.5 3.0 2.5e-08 33.4 0.1 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KUM66887.1 - 1.8e-18 65.9 3.3 4.7e-09 35.8 0.1 5.1 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.6 KUM66887.1 - 3.5e-18 65.9 3.1 1.1e-05 26.0 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KUM66887.1 - 1.3e-16 59.8 1.8 7.2e-05 23.3 0.0 5.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KUM66887.1 - 5.8e-15 55.6 2.5 0.00042 20.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KUM66887.1 - 9.4e-14 50.7 1.7 0.0069 16.7 0.1 5.0 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KUM66887.1 - 1.6e-13 49.7 0.7 2.4e-06 27.3 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KUM66887.1 - 4.1e-11 42.1 1.3 0.0061 16.5 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 KUM66887.1 - 4.1e-11 43.1 0.3 0.0065 16.8 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KUM66887.1 - 5.3e-10 39.5 4.2 1.9e-06 28.0 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KUM66887.1 - 1.1e-09 38.2 1.9 0.0018 18.4 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KUM66887.1 - 6.6e-06 26.3 2.3 0.00035 20.8 0.4 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KUM66887.1 - 1.7e-05 25.1 1.6 1.1 10.0 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KUM66887.1 - 9.5e-05 21.7 0.8 0.27 10.4 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.12 KUM66887.1 - 0.00032 20.6 0.1 0.14 12.2 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat MIT PF04212.18 KUM66887.1 - 0.001 19.1 0.3 4.4 7.5 0.1 4.1 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KUM66887.1 - 0.0036 17.1 4.0 0.057 13.3 0.9 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF1641 PF07849.11 KUM66887.1 - 0.066 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TOM20_plant PF06552.12 KUM66887.1 - 0.11 12.3 0.1 3.6 7.3 0.0 2.9 3 1 1 4 4 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF4192 PF13830.6 KUM66887.1 - 0.35 10.9 6.2 1.8 8.5 6.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) Amidase PF01425.21 KUM66888.1 - 9.7e-92 308.3 0.0 6.5e-91 305.5 0.0 1.9 1 1 0 1 1 1 1 Amidase Ribonuc_L-PSP PF01042.21 KUM66889.1 - 1.3e-18 67.1 0.0 1.6e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Aldedh PF00171.22 KUM66890.1 - 2.9e-157 523.9 0.1 3.5e-157 523.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1707 PF08044.11 KUM66891.1 - 0.14 12.2 0.0 0.41 10.8 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1707) 2-Hacid_dh_C PF02826.19 KUM66892.1 - 1.4e-39 135.2 0.3 2.1e-39 134.7 0.3 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KUM66892.1 - 4.1e-10 39.4 0.1 6.1e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KUM66892.1 - 0.11 13.0 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF4242 PF14026.6 KUM66892.1 - 0.12 12.6 0.2 0.28 11.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) Gp_dh_N PF00044.24 KUM66892.1 - 0.15 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF4061 PF13270.6 KUM66893.1 - 0.099 13.0 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) CDP-OH_P_transf PF01066.21 KUM66894.1 - 6.7e-15 55.6 0.2 6.7e-15 55.6 0.2 3.3 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DUF3659 PF12396.8 KUM66895.1 - 2.9e-18 65.5 3.3 7.8e-18 64.2 3.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) RPW8 PF05659.11 KUM66895.1 - 0.00043 20.0 1.4 0.0027 17.4 0.5 2.1 2 0 0 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 EspB PF05802.11 KUM66895.1 - 0.006 16.6 0.0 0.7 9.9 0.0 2.2 1 1 1 2 2 2 2 Enterobacterial EspB protein Pex19 PF04614.12 KUM66895.1 - 0.0097 15.7 0.5 0.021 14.6 0.2 1.7 2 0 0 2 2 2 1 Pex19 protein family AIP3 PF03915.13 KUM66895.1 - 0.08 12.0 2.2 0.11 11.6 2.2 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 CorA PF01544.18 KUM66895.1 - 0.28 10.4 0.2 0.37 10.1 0.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein GCIP PF13324.6 KUM66895.1 - 3.1 7.3 6.1 5 6.6 4.2 1.9 1 1 1 2 2 2 0 Grap2 and cyclin-D-interacting DUF3659 PF12396.8 KUM66896.1 - 6.2e-117 381.5 55.9 1.8e-20 72.6 0.9 7.9 7 0 0 7 7 7 7 Protein of unknown function (DUF3659) Apolipoprotein PF01442.18 KUM66896.1 - 6.6e-05 22.9 15.1 6.6e-05 22.9 15.1 2.3 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 KUM66896.1 - 0.005 17.3 34.2 0.24 11.9 9.4 4.8 2 1 1 3 3 3 1 YtxH-like protein Mitofilin PF09731.9 KUM66896.1 - 0.017 14.0 13.0 0.029 13.2 13.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Alanine_zipper PF11839.8 KUM66896.1 - 0.044 14.1 35.3 3.2 8.2 11.0 4.4 2 1 2 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein DUF883 PF05957.13 KUM66896.1 - 0.049 14.2 25.4 0.11 13.2 7.6 4.5 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) Laminin_II PF06009.12 KUM66896.1 - 0.072 13.1 9.8 2 8.4 0.3 3.2 2 1 1 3 3 3 0 Laminin Domain II ISG65-75 PF11727.8 KUM66896.1 - 7.6 5.7 30.6 0.014 14.6 8.2 2.7 2 1 1 3 3 3 0 Invariant surface glycoprotein DUF3584 PF12128.8 KUM66896.1 - 8 3.8 10.3 12 3.2 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mitoc_mL59 PF18126.1 KUM66898.1 - 0.36 11.1 3.0 0.24 11.7 0.4 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein mL59 LSM PF01423.22 KUM66899.1 - 5.3e-18 64.5 0.2 7e-18 64.1 0.2 1.2 1 0 0 1 1 1 1 LSM domain Peptidase_M1_N PF17900.1 KUM66900.1 - 0.00035 20.8 0.0 0.4 10.9 0.0 2.4 1 1 1 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 KUM66900.1 - 0.023 14.3 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M1 domain DUF917 PF06032.12 KUM66902.1 - 0.064 12.1 0.0 0.067 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF917) Lactonase PF10282.9 KUM66904.1 - 4.1e-76 256.5 0.0 5.5e-76 256.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller GMC_oxred_N PF00732.19 KUM66905.1 - 2.7e-83 279.8 0.1 5.4e-83 278.8 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KUM66905.1 - 2.6e-27 96.1 0.0 4.6e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KUM66905.1 - 0.00083 19.5 0.1 0.0037 17.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KUM66905.1 - 0.001 18.7 0.1 0.0025 17.4 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KUM66905.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KUM66905.1 - 0.0024 17.0 0.1 0.013 14.6 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KUM66905.1 - 0.0079 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein OATP PF03137.20 KUM66906.1 - 0.14 10.5 0.3 0.31 9.3 0.4 1.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family 2OG-FeII_Oxy PF03171.20 KUM66907.1 - 1.8e-19 70.1 0.0 4.9e-19 68.7 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KUM66907.1 - 3.3e-15 56.9 0.0 5.5e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Terpene_synth_C PF03936.16 KUM66908.1 - 0.055 12.8 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain ACPS PF01648.20 KUM66908.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily AbiEii PF08843.11 KUM66909.1 - 0.016 15.2 0.2 0.033 14.2 0.2 1.4 1 1 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system DUF2204 PF09970.9 KUM66909.1 - 0.096 12.3 0.0 0.34 10.5 0.0 1.8 1 1 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) Pyr_redox_2 PF07992.14 KUM66912.1 - 4.6e-18 65.5 0.0 7.7e-13 48.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KUM66912.1 - 3.6e-11 42.9 0.1 4.4e-07 29.4 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KUM66912.1 - 2.7e-06 26.3 0.0 0.00023 20.0 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KUM66912.1 - 5.6e-05 22.9 0.4 0.021 14.4 0.2 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 KUM66912.1 - 0.00018 20.7 0.4 0.0074 15.4 0.0 2.8 2 1 1 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KUM66912.1 - 0.00048 19.3 0.2 0.0017 17.6 0.0 2.0 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 KUM66912.1 - 0.00048 20.3 0.2 0.0014 18.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KUM66912.1 - 0.0023 18.0 0.2 3.3 7.7 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.17 KUM66912.1 - 0.0031 16.8 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KUM66912.1 - 0.0035 16.4 0.1 0.048 12.7 0.0 2.1 1 1 1 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KUM66912.1 - 0.0068 15.7 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KUM66912.1 - 0.012 15.0 0.6 0.046 13.1 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KUM66912.1 - 0.057 12.7 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KUM66912.1 - 0.085 13.4 0.0 0.23 12.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RRM_1 PF00076.22 KUM66913.1 - 6.2e-37 125.3 0.0 5.2e-20 71.0 0.2 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.18 KUM66913.1 - 1.1e-09 37.7 0.1 9.8e-09 34.6 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM66913.1 - 1e-06 28.7 12.9 1.8e-06 28.0 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 KUM66913.1 - 0.025 14.4 0.2 0.061 13.2 0.2 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 RRM_7 PF16367.5 KUM66913.1 - 0.09 12.9 0.1 2.9 8.1 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif p450 PF00067.22 KUM66914.1 - 9.8e-66 222.4 0.0 1.3e-65 222.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Piwi PF02171.17 KUM66915.1 - 1.5e-73 247.7 0.0 2.5e-73 247.0 0.0 1.4 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KUM66915.1 - 5.4e-18 65.9 0.0 9.8e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 KUM66915.1 - 2.4e-12 47.0 0.0 7.7e-12 45.4 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoL1 PF08699.10 KUM66915.1 - 2.8e-10 39.7 0.3 1.3e-09 37.6 0.2 2.2 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 KUM66915.1 - 4e-09 36.4 0.0 9.6e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KUM66915.1 - 8.3e-06 26.0 0.1 1.9e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 Mid domain of argonaute SHS2_Rpb7-N PF03876.17 KUM66917.1 - 3.1e-14 53.1 0.0 6e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KUM66917.1 - 2.9e-10 40.3 0.0 4.6e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.11 KUM66918.1 - 3.6e-25 87.9 2.2 5e-25 87.4 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) ATP-synt_ab PF00006.25 KUM66919.1 - 9.8e-72 241.0 0.0 1.4e-71 240.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KUM66919.1 - 3.4e-48 163.1 0.5 6e-48 162.3 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KUM66919.1 - 3.6e-15 56.2 2.9 9e-15 54.9 2.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RbcS PF12338.8 KUM66919.1 - 4.6 7.5 8.7 2.4 8.4 0.2 2.7 2 0 0 2 2 2 0 Ribulose-1,5-bisphosphate carboxylase small subunit THF_DHG_CYH PF00763.23 KUM66920.1 - 1.9e-25 89.4 0.1 2.8e-25 88.8 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KUM66920.1 - 9.1e-12 44.6 0.0 6.6e-10 38.5 0.0 2.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3143 PF11341.8 KUM66920.1 - 0.074 13.4 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) Peroxin-13_N PF04088.13 KUM66921.1 - 1.4e-52 177.9 0.1 1.9e-52 177.4 0.1 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KUM66921.1 - 2.4e-09 36.7 0.0 4.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KUM66921.1 - 6.3e-08 32.1 0.0 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KUM66921.1 - 2.3e-05 24.2 0.1 3.9e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 KUM66921.1 - 0.21 12.0 0.0 0.37 11.2 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain SPX PF03105.19 KUM66922.1 - 3.8 7.3 6.4 5.2 6.9 6.4 1.2 1 0 0 1 1 1 0 SPX domain ERO1 PF04137.15 KUM66924.1 - 1.9e-134 448.4 0.0 2.4e-134 448.0 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PALP PF00291.25 KUM66925.1 - 9.5e-56 189.4 0.1 1.4e-55 188.8 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.17 KUM66926.1 - 6.3e-40 137.4 0.0 9.1e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KUM66926.1 - 0.06 13.2 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PRT_C PF08372.10 KUM66926.1 - 0.62 9.8 2.6 0.51 10.1 0.7 1.8 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal APG6 PF04111.12 KUM66927.1 - 3.8e-72 242.0 0.0 5.5e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KUM66927.1 - 8.1e-39 133.2 3.7 1.2e-38 132.6 3.7 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region KASH_CCD PF14662.6 KUM66927.1 - 0.064 13.1 2.2 0.1 12.4 2.2 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 KUM66927.1 - 0.31 11.1 3.5 0.6 10.1 3.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MbeD_MobD PF04899.12 KUM66927.1 - 1.4 9.1 3.9 2 8.6 1.1 2.3 1 1 1 2 2 2 0 MbeD/MobD like ERM PF00769.19 KUM66927.1 - 1.4 8.6 7.0 2.8 7.7 7.0 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Jnk-SapK_ap_N PF09744.9 KUM66927.1 - 4.4 7.5 6.6 8.2 6.6 6.6 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Scm3 PF10384.9 KUM66928.1 - 5.1e-21 74.2 1.1 6.9e-21 73.7 0.0 1.9 2 0 0 2 2 2 1 Centromere protein Scm3 SANT_DAMP1_like PF16282.5 KUM66928.1 - 0.052 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Abhydrolase_6 PF12697.7 KUM66929.1 - 7.5e-11 43.0 1.8 8.5e-11 42.9 1.8 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 KUM66930.1 - 2.6e-19 70.7 6.8 3e-19 70.5 6.8 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KUM66930.1 - 0.011 15.4 0.5 0.021 14.5 0.3 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF676 PF05057.14 KUM66930.1 - 0.013 15.0 0.2 0.021 14.4 0.2 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_2 PF01674.18 KUM66930.1 - 0.032 13.7 0.1 0.047 13.2 0.1 1.2 1 0 0 1 1 1 0 Lipase (class 2) Hydrolase_4 PF12146.8 KUM66930.1 - 0.058 12.6 0.3 0.12 11.6 0.3 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KUM66930.1 - 0.15 11.7 0.5 0.21 11.3 0.5 1.2 1 0 0 1 1 1 0 PGAP1-like protein Fungal_trans PF04082.18 KUM66931.1 - 4.5e-19 68.5 1.8 7e-19 67.9 1.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KUM66931.1 - 8e-07 29.2 14.9 7.1e-05 23.0 5.5 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KUM66931.1 - 0.00085 19.6 14.3 0.037 14.5 5.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KUM66931.1 - 0.0019 18.9 12.6 0.25 12.3 4.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KUM66931.1 - 0.039 14.6 0.5 1.8 9.2 0.0 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 KUM66931.1 - 0.88 9.9 6.1 1.3 9.4 3.7 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KUM66931.1 - 1.5 9.0 3.7 5.5 7.2 3.7 2.0 1 0 0 1 1 1 0 Zinc ribbon domain UPRTase PF14681.6 KUM66932.1 - 5.8e-75 251.3 0.0 6.7e-75 251.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KUM66932.1 - 1.5e-06 27.9 0.1 3.5e-06 26.6 0.1 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Sin_N PF04801.13 KUM66934.1 - 1.5e-26 93.6 0.1 4.2e-26 92.1 0.1 1.5 1 1 0 1 1 1 1 Sin-like protein conserved region NIR_SIR PF01077.22 KUM66935.1 - 4.6e-51 172.5 0.0 3e-44 150.3 0.0 2.9 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KUM66935.1 - 1.6e-27 95.2 0.0 5.5e-13 48.6 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KUM66935.1 - 2e-26 92.9 0.0 4.1e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 KUM66935.1 - 5.5e-08 32.8 0.1 1.2e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Abhydrolase_3 PF07859.13 KUM66936.1 - 3.1e-27 95.8 0.0 4.1e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KUM66936.1 - 1.3e-12 47.3 0.0 3.2e-12 46.0 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KUM66936.1 - 0.022 14.2 0.0 0.067 12.7 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family MmgE_PrpD PF03972.14 KUM66937.1 - 2.5e-130 435.0 3.7 2.8e-130 434.8 3.7 1.0 1 0 0 1 1 1 1 MmgE/PrpD family AAA_29 PF13555.6 KUM66937.1 - 0.1 12.3 1.9 0.38 10.5 0.2 2.6 2 1 1 3 3 3 0 P-loop containing region of AAA domain Kei1 PF08552.11 KUM66938.1 - 1.9e-68 230.1 2.6 2.3e-68 229.8 2.6 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 ATP-synt_C PF00137.21 KUM66939.1 - 7.9e-25 87.0 26.9 3.8e-14 52.8 11.1 2.3 2 0 0 2 2 2 2 ATP synthase subunit C Oxidored_q2 PF00420.24 KUM66939.1 - 0.44 10.2 8.1 0.18 11.5 2.8 2.9 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ras PF00071.22 KUM66940.1 - 2.7e-59 199.4 0.2 3.5e-59 199.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM66940.1 - 4.4e-37 127.0 0.4 7.9e-37 126.1 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM66940.1 - 1.4e-17 63.7 0.1 1.7e-17 63.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KUM66940.1 - 1.2e-06 28.5 0.3 0.001 19.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KUM66940.1 - 4.5e-06 26.3 0.1 2.9e-05 23.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KUM66940.1 - 5.6e-06 25.9 0.0 8.4e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KUM66940.1 - 1.4e-05 25.1 0.0 2.4e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KUM66940.1 - 4.2e-05 23.0 0.2 5.4e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TIR_2 PF13676.6 KUM66940.1 - 0.086 13.4 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 TIR domain AAA_7 PF12775.7 KUM66940.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_pol PF00940.19 KUM66941.1 - 1.3e-183 610.6 0.0 1.7e-183 610.2 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KUM66941.1 - 4.7e-91 305.7 1.3 7.4e-91 305.0 1.3 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Fungal_trans PF04082.18 KUM66942.1 - 2.1e-39 135.1 0.0 3.7e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM66942.1 - 2.5e-09 37.1 9.0 4.2e-09 36.4 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KUM66942.1 - 0.0051 15.7 0.0 0.012 14.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.6 KUM66943.1 - 6.9e-23 81.3 0.0 1.2e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KUM66943.1 - 4.2e-12 46.6 0.0 1.2e-11 45.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KUM66943.1 - 5.9e-11 42.4 0.0 3.1e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KUM66943.1 - 1.9e-09 38.1 0.0 9.1e-09 36.0 0.0 2.1 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KUM66943.1 - 5.3e-09 36.6 0.0 2.3e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KUM66943.1 - 0.00052 19.5 0.0 0.0032 17.0 0.0 2.2 3 0 0 3 3 3 1 Putative methyltransferase FtsJ PF01728.19 KUM66943.1 - 0.0019 18.3 0.0 0.0056 16.8 0.0 1.7 2 1 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KUM66943.1 - 0.014 14.8 0.0 0.32 10.3 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 KUM66943.1 - 0.044 13.3 0.0 0.41 10.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.20 KUM66943.1 - 0.06 12.6 0.0 0.16 11.2 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KUM66943.1 - 0.2 11.0 0.0 0.6 9.4 0.0 1.7 1 1 0 1 1 1 0 O-methyltransferase domain Zn_clus PF00172.18 KUM66944.1 - 8.1e-09 35.5 6.4 1.3e-08 34.8 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SSP160 PF06933.11 KUM66944.1 - 5.6 5.0 13.7 9.8 4.2 13.7 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Melibiase_2 PF16499.5 KUM66945.1 - 2.2e-18 66.4 0.0 3.9e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 KUM66945.1 - 0.00025 20.1 0.3 0.00047 19.2 0.3 1.4 1 0 0 1 1 1 1 Melibiase Ricin_B_lectin PF00652.22 KUM66945.1 - 0.076 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain PhyH PF05721.13 KUM66946.1 - 1.1e-09 38.9 0.2 3e-09 37.4 0.2 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Dcc1 PF09724.9 KUM66947.1 - 2.8e-21 76.2 0.0 3.6e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Acetyltransf_7 PF13508.7 KUM66948.1 - 6.2e-06 26.5 0.0 1.2e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KUM66948.1 - 0.00025 21.1 0.1 0.0011 19.1 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KUM66948.1 - 0.00034 20.8 0.0 0.00091 19.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KUM66948.1 - 0.00047 20.1 0.0 0.00093 19.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KUM66948.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_15 PF17013.5 KUM66948.1 - 0.021 14.3 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase HORMA PF02301.18 KUM66949.1 - 6.9e-12 45.4 0.0 9.1e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 HORMA domain IBN_N PF03810.19 KUM66950.1 - 1.9e-08 34.1 0.3 2.5e-07 30.5 0.1 3.0 2 1 1 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KUM66950.1 - 0.00032 20.8 0.5 0.023 14.7 0.0 4.0 4 1 0 4 4 4 1 Exportin 1-like protein CAS_CSE1 PF03378.15 KUM66950.1 - 0.00065 18.3 0.0 0.0015 17.1 0.0 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Proteasom_PSMB PF10508.9 KUM66950.1 - 0.0031 16.1 0.0 0.66 8.4 0.0 2.5 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit RIX1 PF08167.12 KUM66950.1 - 0.0076 16.0 0.0 0.12 12.2 0.0 3.0 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis GNAT_like PF18407.1 KUM66950.1 - 0.028 14.7 1.0 1.1 9.7 0.0 3.3 3 0 0 3 3 3 0 GCN5-related N-acetyltransferase like domain SseC PF04888.12 KUM66950.1 - 0.15 11.6 0.8 1.1 8.8 0.0 2.4 3 0 0 3 3 3 0 Secretion system effector C (SseC) like family RICTOR_N PF14664.6 KUM66950.1 - 0.15 11.0 0.4 0.64 9.0 0.1 2.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term Het-C PF07217.11 KUM66951.1 - 3.3e-268 890.9 0.0 5.3e-267 886.9 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Peptidase_C48 PF02902.19 KUM66953.1 - 7.4e-28 97.9 0.0 1.2e-27 97.2 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain zf-HIT PF04438.16 KUM66955.1 - 1.1e-10 41.2 10.2 2.2e-10 40.2 10.2 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KUM66955.1 - 1.1 9.4 8.1 2.2 8.5 8.1 1.5 1 0 0 1 1 1 0 MYND finger adh_short PF00106.25 KUM66956.1 - 1.2e-25 90.1 0.0 1.5e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KUM66956.1 - 2.6e-22 79.5 0.0 3.3e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KUM66956.1 - 3.5e-06 27.1 0.0 5.2e-06 26.5 0.0 1.3 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KUM66956.1 - 0.00038 19.9 0.0 0.00049 19.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) MlaE PF02405.16 KUM66956.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Permease MlaE DUF1598 PF07643.11 KUM66957.1 - 0.055 13.7 0.0 0.095 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) Pap_E4 PF02711.14 KUM66959.1 - 0.69 10.9 5.6 4.1 8.4 0.7 2.1 2 0 0 2 2 2 0 E4 protein Ras PF00071.22 KUM66960.1 - 2e-48 164.0 0.0 2.6e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KUM66960.1 - 5.5e-21 75.0 0.0 8.3e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KUM66960.1 - 3.2e-05 23.4 0.0 0.00019 20.9 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 KUM66960.1 - 0.037 13.6 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 KUM66960.1 - 0.049 13.1 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PAP2 PF01569.21 KUM66961.1 - 3.7e-17 62.3 2.0 3.7e-17 62.3 2.0 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KUM66961.1 - 0.00069 19.4 6.2 0.0016 18.2 6.2 1.6 1 0 0 1 1 1 1 PAP2 superfamily LuxQ-periplasm PF09308.10 KUM66962.1 - 0.027 14.0 0.1 0.044 13.3 0.1 1.2 1 0 0 1 1 1 0 LuxQ, periplasmic C5-epim_C PF06662.13 KUM66962.1 - 0.063 12.8 1.4 0.078 12.5 0.1 1.7 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus GILT PF03227.16 KUM66963.1 - 1.7e-12 47.5 1.2 1.7e-12 47.5 1.2 2.3 2 1 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Hexokinase_1 PF00349.21 KUM66964.1 - 6.1e-61 205.8 0.0 8.5e-61 205.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KUM66964.1 - 1.2e-47 162.4 0.0 2.1e-46 158.3 0.0 2.2 1 1 0 1 1 1 1 Hexokinase Snf7 PF03357.21 KUM66964.1 - 1.7 8.2 6.0 3.7 7.1 6.0 1.6 1 0 0 1 1 1 0 Snf7 HeLo PF14479.6 KUM66966.1 - 2.1e-33 115.9 1.8 2.1e-33 115.9 1.8 2.1 2 0 0 2 2 2 1 Prion-inhibition and propagation Goodbye PF17109.5 KUM66966.1 - 1.7e-14 54.3 5.3 8.4e-14 52.1 0.2 3.5 3 1 1 4 4 4 1 fungal STAND N-terminal Goodbye domain Ses_B PF17046.5 KUM66966.1 - 4.2e-06 26.6 6.5 4.2e-06 26.6 6.5 1.7 2 0 0 2 2 2 1 SesB domain on fungal death-pathway protein Nucleoporin_C PF03177.14 KUM66966.1 - 0.017 13.9 2.0 0.4 9.4 0.2 2.4 2 0 0 2 2 2 0 Non-repetitive/WGA-negative nucleoporin C-terminal WD40 PF00400.32 KUM66967.1 - 1.7e-71 234.4 27.3 1.1e-07 32.4 0.0 13.1 12 0 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM66967.1 - 4.2e-30 103.9 1.1 1.2e-05 25.5 0.0 10.1 3 2 6 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KUM66967.1 - 1.2e-16 60.7 8.8 0.042 12.8 0.0 8.9 4 4 4 9 9 9 5 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KUM66967.1 - 2.9e-10 40.3 0.1 5.6e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 KUM66967.1 - 8e-10 38.4 10.7 8.1 6.5 0.0 9.8 11 0 0 11 11 11 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KUM66967.1 - 0.0001 21.1 10.3 0.0016 17.2 1.0 4.6 4 1 0 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KUM66967.1 - 0.00011 21.1 2.4 0.92 8.2 0.0 3.9 3 1 1 4 4 4 3 Nup133 N terminal like eIF2A PF08662.11 KUM66967.1 - 0.00012 22.1 0.6 0.66 9.8 0.0 4.7 2 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KUM66967.1 - 0.00028 19.4 0.2 0.33 9.2 0.0 4.2 3 2 1 5 5 5 1 WD repeat-containing and planar cell polarity effector protein Fritz Ses_B PF17046.5 KUM66967.1 - 0.0021 18.0 0.7 0.0044 16.9 0.7 1.5 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein CobA_CobO_BtuR PF02572.15 KUM66967.1 - 0.0022 18.3 0.0 0.0044 17.3 0.0 1.5 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_19 PF13245.6 KUM66967.1 - 0.015 15.7 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytochrom_D1 PF02239.16 KUM66967.1 - 0.024 13.2 0.3 3.5 6.0 0.1 3.8 3 1 0 5 5 5 0 Cytochrome D1 heme domain KAP_NTPase PF07693.14 KUM66967.1 - 0.044 13.0 0.1 0.12 11.6 0.1 1.5 1 1 0 1 1 1 0 KAP family P-loop domain Proteasome_A_N PF10584.9 KUM66967.1 - 0.051 13.3 13.8 2.1 8.1 0.1 7.1 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature ResIII PF04851.15 KUM66967.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4875 PF16175.5 KUM66967.1 - 0.071 13.2 4.2 14 5.9 0.1 4.3 3 1 2 5 5 5 0 Domain of unknown function (DUF4875) MFS_1 PF07690.16 KUM66969.1 - 4.8e-36 124.4 24.3 4.8e-36 124.4 24.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily TssN PF17555.2 KUM66969.1 - 7.9 5.8 7.7 0.31 10.4 0.5 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssN FAD_binding_4 PF01565.23 KUM66970.1 - 1.6e-19 70.0 0.0 3.5e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KUM66970.1 - 3e-09 36.8 0.3 7.1e-09 35.6 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KUM66970.1 - 0.17 11.2 0.2 0.28 10.6 0.2 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Ses_B PF17046.5 KUM66971.1 - 7.1e-11 41.8 2.7 7.1e-11 41.8 2.7 1.6 2 0 0 2 2 2 1 SesB domain on fungal death-pathway protein DUF676 PF05057.14 KUM66971.1 - 1.3e-07 31.4 0.0 2.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KUM66971.1 - 4.1e-07 30.8 0.0 4.9e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KUM66971.1 - 0.00017 21.4 0.0 0.00033 20.5 0.0 1.4 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_9 PF10081.9 KUM66971.1 - 0.025 13.7 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family vATP-synt_E PF01991.18 KUM66971.1 - 0.16 11.4 0.1 0.38 10.1 0.0 1.6 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit PEMT PF04191.13 KUM66972.1 - 1.4e-60 202.3 6.8 3.1e-37 127.2 0.6 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase SKICH PF17751.1 KUM66972.1 - 0.0027 18.2 0.1 0.038 14.5 0.1 2.3 1 1 0 1 1 1 1 SKICH domain HECW_N PF16562.5 KUM66972.1 - 0.0061 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 RNase_PH PF01138.21 KUM66973.1 - 1e-31 110.2 0.0 2e-31 109.2 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Allexi_40kDa PF05549.11 KUM66974.1 - 0.11 12.0 0.4 0.2 11.2 0.4 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein P22_Tail-4 PF11650.8 KUM66974.1 - 0.16 11.9 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 P22 tail accessory factor ProRS-C_1 PF09180.11 KUM66975.1 - 7.8e-23 80.5 1.5 1.7e-22 79.4 1.5 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KUM66975.1 - 1.1e-18 67.8 0.0 1.8e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KUM66975.1 - 2.5e-10 40.4 0.0 1.3e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain Cpn60_TCP1 PF00118.24 KUM66976.1 - 1.8e-149 498.5 18.2 2.1e-149 498.3 18.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.32 KUM66977.1 - 1.3e-16 60.6 2.5 0.00013 22.7 0.1 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KUM66977.1 - 4.7e-08 33.2 0.0 0.015 15.6 0.0 4.6 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain NmrA PF05368.13 KUM66978.1 - 1.4e-32 113.1 0.0 1.9e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KUM66978.1 - 3.5e-23 82.4 0.0 2.3e-22 79.8 0.0 1.9 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KUM66978.1 - 2.4e-05 23.9 0.1 0.0002 20.9 0.1 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KUM66978.1 - 0.011 15.9 0.0 0.074 13.2 0.0 2.2 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 KUM66978.1 - 0.042 14.4 0.0 0.1 13.2 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 KUM66978.1 - 0.064 12.7 0.4 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase 3Beta_HSD PF01073.19 KUM66978.1 - 0.077 12.0 0.0 0.17 10.8 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KUM66978.1 - 0.097 11.8 0.1 0.6 9.2 0.1 2.0 2 0 0 2 2 2 0 Male sterility protein Glycoprotein_B PF00606.18 KUM66979.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B ectodomain Sulfatase PF00884.23 KUM66980.1 - 6.9e-44 150.5 0.0 8.8e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KUM66980.1 - 0.00011 21.9 0.0 0.34 10.5 0.0 2.5 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KUM66980.1 - 0.00069 19.8 0.4 0.0018 18.5 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 KUM66980.1 - 0.066 11.8 0.0 0.099 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) bZIP_1 PF00170.21 KUM66981.1 - 2e-05 24.6 7.5 2.9e-05 24.1 7.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KUM66981.1 - 0.0002 21.8 5.3 0.00031 21.2 5.3 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KUM66981.1 - 0.00021 21.3 8.7 0.00031 20.8 8.7 1.2 1 0 0 1 1 1 1 Basic region leucine zipper Macoilin PF09726.9 KUM66981.1 - 0.011 14.4 2.1 0.013 14.1 2.1 1.0 1 0 0 1 1 1 0 Macoilin family CASP_C PF08172.12 KUM66981.1 - 0.074 12.4 0.4 0.099 12.0 0.4 1.1 1 0 0 1 1 1 0 CASP C terminal Ank_2 PF12796.7 KUM66982.1 - 1.9e-26 92.5 0.0 4.4e-08 33.6 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KUM66982.1 - 2.5e-19 67.3 0.1 0.15 12.7 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 KUM66982.1 - 1.3e-18 66.5 0.6 0.0044 17.4 0.0 7.8 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 KUM66982.1 - 1.7e-18 66.7 0.1 0.00025 21.5 0.0 6.9 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KUM66982.1 - 1.2e-15 57.3 0.7 0.026 14.8 0.0 6.5 4 2 1 5 5 5 5 Ankyrin repeats (many copies) F-box PF00646.33 KUM66982.1 - 0.00045 20.0 0.1 0.00091 19.0 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KUM66982.1 - 0.00047 20.0 1.1 0.00099 19.0 1.1 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KUM66982.1 - 0.0019 18.1 0.3 0.013 15.3 0.5 2.1 2 0 0 2 2 2 1 F-box ADH_N PF08240.12 KUM66983.1 - 8e-28 96.5 0.2 1.3e-27 95.8 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KUM66983.1 - 2.1e-27 95.7 0.3 3.2e-27 95.0 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KUM66983.1 - 8.8e-08 31.9 0.5 1.2e-07 31.4 0.5 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 KUM66983.1 - 0.0048 16.8 0.0 0.018 15.0 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated FAD_binding_3 PF01494.19 KUM66983.1 - 0.0049 16.2 0.4 0.0087 15.3 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain ADH_zinc_N_2 PF13602.6 KUM66983.1 - 0.0059 17.7 0.1 0.01 16.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 KUM66983.1 - 0.027 14.5 0.3 0.088 12.9 0.1 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 KUM66983.1 - 0.047 12.9 0.6 0.073 12.3 0.6 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KUM66983.1 - 0.069 13.7 0.4 2.1 9.0 0.6 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KUM66983.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Asp PF00026.23 KUM66984.1 - 2.8e-59 201.1 1.0 3.6e-59 200.8 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KUM66984.1 - 9.2e-08 32.5 0.8 0.0036 17.6 0.5 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KUM66984.1 - 6.7e-05 23.5 0.0 0.35 11.6 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KUM66984.1 - 0.00033 21.2 0.0 0.54 10.9 0.0 2.6 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KUM66984.1 - 0.03 14.1 0.0 0.078 12.8 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DUF4452 PF14618.6 KUM66985.1 - 2.2e-71 239.2 9.9 3.1e-71 238.7 9.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Ank_2 PF12796.7 KUM66986.1 - 3.7e-21 75.5 0.1 2.1e-10 41.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KUM66986.1 - 5.9e-20 71.4 0.1 6.5e-08 33.0 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KUM66986.1 - 4.6e-17 61.6 0.9 1.5e-05 25.2 0.2 5.3 4 1 1 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KUM66986.1 - 1.6e-16 58.7 0.9 0.00016 21.8 0.1 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KUM66986.1 - 2.8e-15 56.2 0.8 2.1e-08 34.3 0.1 4.2 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Clp_N PF02861.20 KUM66986.1 - 1.2 9.3 3.5 18 5.6 0.1 3.2 3 0 0 3 3 3 0 Clp amino terminal domain, pathogenicity island component tRNA_bind PF01588.20 KUM66987.1 - 8.7e-22 77.1 0.0 7.3e-21 74.1 0.0 2.2 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 KUM66987.1 - 8.4e-05 22.5 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KUM66987.1 - 0.012 15.8 0.0 0.012 15.8 0.0 2.2 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Ferlin_C PF16165.5 KUM66987.1 - 2.4 8.1 5.0 4.1 7.3 5.0 1.3 1 0 0 1 1 1 0 Ferlin C-terminus Anp1 PF03452.14 KUM66988.1 - 1.7e-112 375.1 0.0 2.4e-112 374.7 0.0 1.2 1 0 0 1 1 1 1 Anp1 KR PF08659.10 KUM66989.1 - 7.4e-09 35.8 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KUM66989.1 - 1.1e-07 31.6 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KUM66989.1 - 0.083 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KUM66989.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KUM66989.1 - 0.17 11.0 0.2 0.68 9.0 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KUM66989.1 - 0.18 10.9 0.1 0.53 9.4 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF4813 PF16072.5 KUM66990.1 - 0.61 9.7 4.3 0.22 11.1 2.1 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4813) CRCB PF02537.15 KUM66991.1 - 1.7e-37 127.6 11.9 1.6e-21 76.4 6.9 2.5 2 1 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) RNA_pol_Rpc4 PF05132.14 KUM66992.1 - 4.9e-34 117.9 0.1 4.9e-34 117.9 0.1 3.7 2 2 2 4 4 4 1 RNA polymerase III RPC4 Cyclin_N PF00134.23 KUM66994.1 - 8.5e-43 145.1 0.1 1.9e-42 144.0 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KUM66994.1 - 5.7e-32 110.3 0.0 1.1e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zn_clus PF00172.18 KUM66995.1 - 0.0043 17.2 13.0 0.0079 16.3 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 KUM66995.1 - 0.12 11.9 0.1 0.33 10.5 0.1 1.8 1 0 0 1 1 1 0 Histone chaperone domain CHZ HA2 PF04408.23 KUM66996.1 - 1.6e-18 67.0 0.5 4.4e-17 62.3 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KUM66996.1 - 2.5e-15 56.6 0.0 4.8e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KUM66996.1 - 1.8e-13 50.8 0.0 4.1e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 KUM66996.1 - 2.2e-13 50.5 0.0 5.2e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 KUM66996.1 - 2.6e-10 40.3 0.0 4.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 KUM66996.1 - 0.0051 16.3 0.0 0.009 15.5 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein T2SSE PF00437.20 KUM66996.1 - 0.0073 15.4 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 KUM66996.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DND1_DSRM PF14709.7 KUM66996.1 - 0.014 15.7 0.0 0.044 14.1 0.0 1.9 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 ATPase PF06745.13 KUM66996.1 - 0.017 14.5 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 KUM66996.1 - 0.02 15.1 2.9 0.52 10.6 2.9 2.4 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KUM66996.1 - 0.088 12.8 0.0 0.26 11.3 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KUM66996.1 - 0.097 12.4 0.1 0.29 10.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain dsRBD2 PF17842.1 KUM66996.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 AAA_23 PF13476.6 KUM66996.1 - 0.17 12.4 0.1 0.17 12.4 0.1 1.7 2 0 0 2 2 1 0 AAA domain DUF2417 PF10329.9 KUM66997.1 - 0.0024 17.4 10.7 0.0026 17.2 10.7 1.0 1 0 0 1 1 1 1 Region of unknown function (DUF2417) TRAP_alpha PF03896.16 KUM66998.1 - 8e-15 54.8 0.0 1.3e-14 54.1 0.0 1.4 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit LodA_N PF17990.1 KUM66998.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 L-Lysine epsilon oxidase N-terminal zf-C2HE PF16278.5 KUM66999.1 - 7.3e-20 71.2 0.1 1.7e-19 70.0 0.1 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 KUM66999.1 - 2.1e-17 63.6 0.5 5.2e-17 62.4 0.5 1.7 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KUM66999.1 - 2.4e-16 60.2 6.1 2.7e-15 56.8 6.1 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding MoCF_biosynth PF00994.24 KUM67000.1 - 1.3e-45 154.6 0.0 1.3e-22 80.0 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KUM67000.1 - 2.5e-40 137.8 2.2 4.8e-40 136.9 2.2 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KUM67000.1 - 3.7e-14 52.7 0.4 1.2e-13 51.0 0.2 2.1 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) DUF2457 PF10446.9 KUM67000.1 - 0.22 10.7 2.1 0.34 10.0 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DDHD PF02862.17 KUM67001.1 - 3.7e-25 89.4 0.0 1.4e-14 54.8 0.0 2.8 2 1 1 3 3 3 2 DDHD domain Abhydrolase_6 PF12697.7 KUM67001.1 - 0.096 13.3 1.9 0.12 13.0 0.1 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family PROL5-SMR PF15621.6 KUM67001.1 - 0.29 11.7 3.0 0.46 11.0 0.7 2.6 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family FAD_binding_3 PF01494.19 KUM67003.1 - 2.3e-72 244.2 0.0 2.9e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KUM67003.1 - 1e-37 129.7 0.1 1.8e-37 128.9 0.1 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 KUM67003.1 - 0.019 14.5 0.1 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KUM67003.1 - 0.023 13.9 0.0 0.063 12.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KUM67003.1 - 0.052 13.8 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KUM67003.1 - 0.062 13.9 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KUM67003.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF866 PF05907.13 KUM67004.1 - 6.2e-64 214.6 0.5 7e-64 214.4 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Paired_CXXCH_1 PF09699.10 KUM67004.1 - 0.12 12.1 0.1 0.12 12.1 0.1 1.7 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_c3_2 PF14537.6 KUM67004.1 - 0.41 11.1 4.1 0.79 10.2 2.8 1.9 1 1 1 2 2 2 0 Cytochrome c3 HalOD2 PF18547.1 KUM67004.1 - 2 8.4 4.6 14 5.6 4.7 2.1 1 1 0 1 1 1 0 Halobacterial output domain 2 LSM PF01423.22 KUM67005.1 - 1.7e-16 59.7 0.0 2.2e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain CoxIIa PF08113.11 KUM67005.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family RTA1 PF04479.13 KUM67007.1 - 9.5e-31 107.0 3.9 1.1e-30 106.9 3.9 1.0 1 0 0 1 1 1 1 RTA1 like protein DASH_Dad1 PF08649.10 KUM67009.1 - 4.7e-26 90.8 4.6 5.9e-26 90.4 4.6 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 KUM67009.1 - 0.022 14.7 0.2 0.032 14.2 0.2 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 DUF92 PF01940.16 KUM67011.1 - 2.3e-83 279.2 7.9 2.7e-83 279.0 7.9 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 TMEM154 PF15102.6 KUM67012.1 - 7.1e-05 22.7 1.9 7.7e-05 22.6 1.9 1.1 1 0 0 1 1 1 1 TMEM154 protein family ASFV_J13L PF05568.11 KUM67012.1 - 0.00025 20.8 0.1 0.00028 20.7 0.1 1.0 1 0 0 1 1 1 1 African swine fever virus J13L protein SP_C-Propep PF08999.10 KUM67012.1 - 0.00028 20.6 0.3 0.00035 20.3 0.3 1.1 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide FeoB_associated PF12669.7 KUM67012.1 - 0.006 17.0 2.3 0.0088 16.4 2.3 1.2 1 0 0 1 1 1 1 FeoB-associated Cys-rich membrane protein EphA2_TM PF14575.6 KUM67012.1 - 0.008 17.0 0.0 0.0088 16.9 0.0 1.1 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.6 KUM67012.1 - 0.016 15.6 0.0 0.018 15.5 0.0 1.1 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Sigma_reg_N PF13800.6 KUM67012.1 - 0.017 15.4 0.0 0.02 15.2 0.0 1.1 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF4010 PF13194.6 KUM67012.1 - 0.041 13.6 0.1 0.045 13.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) DUF4381 PF14316.6 KUM67012.1 - 0.063 13.5 0.4 0.095 12.9 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2207 PF09972.9 KUM67012.1 - 0.11 11.2 0.3 0.11 11.2 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ECSCR PF15820.5 KUM67012.1 - 0.13 12.1 1.2 0.17 11.8 1.2 1.1 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF515 PF04415.12 KUM67012.1 - 0.35 9.2 2.0 0.45 8.9 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) FGFR3_TM PF18123.1 KUM67012.1 - 0.8 9.3 9.0 1.6 8.3 9.0 1.5 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain Stevor PF17410.2 KUM67012.1 - 1.7 8.1 5.1 2 7.9 5.1 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame ADH_zinc_N PF00107.26 KUM67013.1 - 5e-08 33.0 0.1 1.1e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KUM67013.1 - 8.1e-07 28.9 0.0 3.7e-06 26.8 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KUM67013.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Na_Ca_ex PF01699.24 KUM67014.1 - 5.9e-23 81.5 32.7 6e-12 45.8 10.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF378 PF04070.12 KUM67014.1 - 7.6 6.5 12.1 0.12 12.2 3.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF378) Na_Ca_ex PF01699.24 KUM67015.1 - 3e-36 124.6 34.5 1.6e-18 67.1 11.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MscL PF01741.18 KUM67015.1 - 2.3 8.6 5.2 1.8 8.9 0.2 2.9 2 1 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL TPR_10 PF13374.6 KUM67016.1 - 2.4e-77 253.0 5.7 3.3e-10 39.5 0.1 8.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 KUM67016.1 - 3.6e-69 229.0 19.2 6.9e-13 48.7 0.5 7.3 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.6 KUM67016.1 - 3.1e-19 67.5 7.1 0.064 13.3 0.1 6.9 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_MalT PF17874.1 KUM67016.1 - 2.5e-16 60.0 9.1 1.5e-09 37.7 0.4 2.2 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 KUM67016.1 - 2.8e-13 48.9 3.2 0.087 13.0 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KUM67016.1 - 9.1e-13 47.3 2.7 0.12 12.7 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 KUM67016.1 - 1.9e-12 46.4 0.2 0.3 11.0 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_4 PF07721.14 KUM67016.1 - 3e-11 42.8 4.9 0.019 15.5 0.6 6.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KUM67016.1 - 3.8e-09 36.3 8.1 2.4 8.7 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KUM67016.1 - 2.7e-08 34.3 6.7 0.13 12.9 0.6 5.9 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 KUM67016.1 - 7.7e-07 29.5 4.6 1.5 9.3 0.1 5.9 4 3 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KUM67016.1 - 3.2e-05 24.4 11.9 2.3 9.3 0.1 6.7 6 2 2 8 8 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KUM67016.1 - 0.00076 20.0 14.1 0.99 10.2 0.1 6.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_5 PF12688.7 KUM67016.1 - 0.0034 17.6 5.4 24 5.2 0.1 4.9 2 2 3 5 5 5 0 Tetratrico peptide repeat ANAPC3 PF12895.7 KUM67016.1 - 0.015 15.5 0.1 7 7.0 0.0 4.1 2 1 3 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TetR_C_18 PF17923.1 KUM67016.1 - 0.043 14.3 0.1 5.5 7.5 0.0 3.4 2 2 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Wzy_C_2 PF11846.8 KUM67016.1 - 0.08 12.9 1.1 4.7 7.1 0.0 3.3 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal PPR PF01535.20 KUM67016.1 - 0.17 12.2 0.1 23 5.5 0.0 4.0 5 0 0 5 5 4 0 PPR repeat Na_Ca_ex PF01699.24 KUM67017.1 - 1.9e-23 83.1 35.9 5.5e-14 52.4 13.2 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1240 PF06836.12 KUM67017.1 - 0.06 13.9 0.7 0.06 13.9 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) PHO4 PF01384.20 KUM67018.1 - 1e-104 350.2 17.3 1.2e-104 350.0 17.3 1.0 1 0 0 1 1 1 1 Phosphate transporter family UPF0444 PF15475.6 KUM67018.1 - 0.32 11.3 8.3 0.54 10.6 0.5 2.9 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 PgpA PF04608.13 KUM67018.1 - 0.8 9.7 7.0 0.33 11.0 0.9 2.8 3 0 0 3 3 3 0 Phosphatidylglycerophosphatase A 7TMR-DISM_7TM PF07695.11 KUM67018.1 - 6.6 6.6 14.0 4.4 7.2 0.2 3.7 3 0 0 3 3 3 0 7TM diverse intracellular signalling Cation_ATPase_C PF00689.21 KUM67019.1 - 1.1e-45 155.6 9.3 1.1e-45 155.6 9.3 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KUM67019.1 - 2.8e-38 131.3 0.3 2.8e-38 131.3 0.3 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 KUM67019.1 - 3.5e-18 65.5 0.0 8.8e-18 64.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KUM67019.1 - 4.1e-17 63.2 0.2 2.1e-16 60.9 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KUM67019.1 - 2.5e-06 27.1 0.8 1.7e-05 24.4 0.0 2.7 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus LptF_LptG PF03739.14 KUM67019.1 - 0.0018 17.2 2.6 0.0018 17.2 2.6 2.0 3 0 0 3 3 3 1 Lipopolysaccharide export system permease LptF/LptG Hydrolase_3 PF08282.12 KUM67019.1 - 0.029 14.1 0.3 0.074 12.8 0.1 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DevR PF01905.16 KUM67019.1 - 0.063 12.3 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 PrgI PF12666.7 KUM67019.1 - 1.7 9.4 5.9 32 5.3 0.1 3.7 3 0 0 3 3 3 0 PrgI family protein Exo_endo_phos PF03372.23 KUM67020.1 - 0.0016 18.0 0.3 0.0049 16.4 0.3 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.17 KUM67020.1 - 0.0017 18.3 0.2 0.0033 17.4 0.2 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain DUF4795 PF16043.5 KUM67022.1 - 0.0084 15.7 1.2 0.01 15.4 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) SNARE PF05739.19 KUM67023.1 - 3.3e-08 33.4 0.8 6e-08 32.6 0.8 1.5 1 0 0 1 1 1 1 SNARE domain DUF4407 PF14362.6 KUM67023.1 - 0.0029 17.0 1.8 0.014 14.8 1.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Use1 PF09753.9 KUM67023.1 - 0.01 15.6 0.7 0.026 14.2 0.7 1.7 1 1 0 1 1 1 0 Membrane fusion protein Use1 ABC_tran_CTD PF16326.5 KUM67023.1 - 0.019 15.2 0.5 0.019 15.2 0.5 2.2 3 0 0 3 3 3 0 ABC transporter C-terminal domain Snapin_Pallidin PF14712.6 KUM67023.1 - 0.064 13.7 2.4 1.3 9.5 0.1 2.6 2 1 0 2 2 2 0 Snapin/Pallidin HrpB7 PF09486.10 KUM67023.1 - 0.088 13.2 0.8 0.088 13.2 0.8 2.6 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Synaptobrevin PF00957.21 KUM67023.1 - 0.41 10.5 2.3 1.1 9.1 2.3 1.8 1 0 0 1 1 1 0 Synaptobrevin XhlA PF10779.9 KUM67023.1 - 1.3 9.3 10.9 9.2 6.5 8.0 3.2 2 1 0 2 2 2 0 Haemolysin XhlA EspB_PE PF18625.1 KUM67023.1 - 3.3 8.2 6.5 0.28 11.7 0.6 2.2 2 2 0 2 2 2 0 ESX-1 secreted protein B PE domain zf-TRAF PF02176.18 KUM67024.1 - 8.4e-12 45.6 28.1 6.8e-08 33.1 4.1 4.1 1 1 3 4 4 4 4 TRAF-type zinc finger zf-RING_UBOX PF13445.6 KUM67024.1 - 2.4e-07 30.7 10.7 9.7e-07 28.7 10.7 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-TRAF_2 PF15965.5 KUM67024.1 - 8.4e-07 29.4 11.0 8.4e-07 29.4 11.0 3.2 1 1 1 3 3 3 2 TRAF-like zinc-finger zf-C3HC4 PF00097.25 KUM67024.1 - 1.5e-06 27.9 10.4 1.5e-06 27.9 10.4 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KUM67024.1 - 3.3e-06 27.1 13.2 3.3e-06 27.1 13.2 2.7 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KUM67024.1 - 8.2e-06 26.1 11.7 8.2e-06 26.1 11.7 3.8 3 2 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 KUM67024.1 - 5.8e-05 23.0 9.9 5.8e-05 23.0 9.9 3.3 3 1 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KUM67024.1 - 0.00025 20.8 9.0 0.00025 20.8 9.0 3.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) TraP PF07296.11 KUM67024.1 - 0.15 11.2 0.9 0.31 10.2 0.9 1.5 1 0 0 1 1 1 0 TraP protein Sina PF03145.16 KUM67024.1 - 7.6 6.4 18.8 1 9.2 0.6 2.8 1 1 2 3 3 3 0 Seven in absentia protein family zf-RING_6 PF14835.6 KUM67024.1 - 7.8 6.5 12.0 6.2 6.8 9.0 2.5 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Fungal_trans PF04082.18 KUM67025.1 - 9e-13 47.9 0.1 1.6e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KUM67025.1 - 1.1e-10 41.4 7.9 2.2e-10 40.5 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinesin PF00225.23 KUM67028.1 - 4.1e-59 200.2 0.3 4.6e-33 114.5 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KUM67028.1 - 6.4e-11 42.4 0.0 1.3e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding ParA PF10609.9 KUM67029.1 - 3.6e-97 324.6 0.0 4.3e-97 324.4 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KUM67029.1 - 8.4e-09 35.6 0.0 1.9e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KUM67029.1 - 6e-06 25.7 1.3 0.00022 20.5 0.3 2.7 1 1 2 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.6 KUM67029.1 - 1.3e-05 25.2 0.1 0.00014 21.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KUM67029.1 - 0.0019 18.1 0.1 0.5 10.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KUM67029.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase MipZ PF09140.11 KUM67029.1 - 0.019 14.3 0.0 0.047 13.0 0.0 1.7 1 1 0 1 1 1 0 ATPase MipZ Fer4_NifH PF00142.18 KUM67029.1 - 0.019 14.4 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_30 PF13604.6 KUM67029.1 - 0.034 13.9 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KUM67029.1 - 0.037 13.8 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 KUM67029.1 - 0.044 13.4 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KUM67029.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KUM67029.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KUM67029.1 - 0.19 11.7 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KUM67029.1 - 0.22 10.7 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Pex14_N PF04695.13 KUM67030.1 - 7.9 7.1 17.6 0.34 11.6 8.0 2.9 1 1 2 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4807 PF16065.5 KUM67031.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4807) Nop14 PF04147.12 KUM67031.1 - 0.054 11.7 2.3 0.071 11.3 2.3 1.2 1 0 0 1 1 1 0 Nop14-like family TPR_2 PF07719.17 KUM67032.1 - 0.025 14.7 0.2 0.54 10.5 0.0 3.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Methyltransf_33 PF10017.9 KUM67033.1 - 5.9e-83 278.5 0.0 9.4e-83 277.9 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KUM67033.1 - 7e-12 45.5 0.1 1.4e-11 44.5 0.1 1.4 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KUM67033.1 - 1.1e-05 26.0 2.0 2.5e-05 24.8 2.0 1.7 1 1 0 1 1 1 1 DinB superfamily Aldedh PF00171.22 KUM67034.1 - 3.8e-132 441.1 0.1 4.3e-132 440.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KUM67034.1 - 3e-05 23.3 0.0 4.5e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) ATP-synt_D PF01813.17 KUM67034.1 - 0.02 14.7 0.1 0.034 14.0 0.1 1.3 1 0 0 1 1 1 0 ATP synthase subunit D Nsp1_C PF05064.13 KUM67034.1 - 0.36 10.6 1.7 0.75 9.6 1.7 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region Sigma54_AID PF00309.20 KUM67034.1 - 0.47 10.3 1.9 0.87 9.5 1.9 1.3 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) LigT_PEase PF02834.16 KUM67035.1 - 0.079 13.2 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 LigT like Phosphoesterase Dabb PF07876.12 KUM67037.1 - 1.7e-25 89.4 0.1 2e-25 89.3 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain TFIIA_gamma_C PF02751.14 KUM67040.1 - 3.2e-26 91.2 2.3 5.4e-26 90.5 2.3 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit S1 PF00575.23 KUM67042.1 - 3.6e-69 229.1 22.8 2e-16 60.1 1.6 12.1 12 0 0 12 12 12 8 S1 RNA binding domain Suf PF05843.14 KUM67042.1 - 1.7e-07 31.6 14.6 0.0041 17.2 0.0 5.1 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KUM67042.1 - 6.1e-07 29.9 0.0 0.0072 16.8 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KUM67042.1 - 3.5e-06 27.4 4.8 0.65 11.0 0.6 6.0 3 1 4 7 7 6 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 KUM67042.1 - 0.0011 18.8 0.0 29 4.7 0.0 5.4 5 0 0 5 5 5 0 RNase II-type exonuclease C-terminal S1 domain TPR_15 PF13429.6 KUM67042.1 - 0.0044 16.3 2.0 0.5 9.5 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KUM67042.1 - 0.0072 17.0 0.4 28 5.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat S1_2 PF13509.6 KUM67042.1 - 0.011 15.8 0.6 3 8.0 0.0 4.0 4 0 0 4 4 4 0 S1 domain Mad3_BUB1_I PF08311.12 KUM67042.1 - 0.013 15.5 0.2 0.025 14.6 0.2 1.5 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 PPR PF01535.20 KUM67042.1 - 0.018 15.2 0.3 13 6.3 0.0 3.7 3 0 0 3 3 3 0 PPR repeat PPR_2 PF13041.6 KUM67042.1 - 0.059 13.6 0.0 36 4.7 0.0 3.5 3 0 0 3 3 3 0 PPR repeat family MFS_1 PF07690.16 KUM67043.1 - 7.8e-07 28.3 6.3 8.7e-05 21.6 0.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KUM67044.1 - 1.1e-85 288.2 20.8 1.3e-85 288.0 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KUM67044.1 - 1.4e-18 66.9 17.9 1.4e-18 66.9 17.9 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Mtr2 PF10429.9 KUM67044.1 - 0.02 14.9 0.0 0.063 13.2 0.0 1.8 2 0 0 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 DUF1304 PF06993.12 KUM67044.1 - 0.12 12.3 13.2 4.5 7.3 1.2 3.9 3 2 0 3 3 3 0 Protein of unknown function (DUF1304) Arm PF00514.23 KUM67045.1 - 1.7e-91 297.8 13.6 4.1e-14 52.0 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KUM67045.1 - 5.2e-27 94.1 4.9 1.3e-26 92.9 4.9 1.7 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KUM67045.1 - 8.7e-24 82.8 3.7 1.9e-23 81.8 3.7 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 KUM67045.1 - 3.7e-20 72.0 6.2 1.3e-08 35.2 0.0 6.3 4 3 3 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 KUM67045.1 - 7.7e-18 64.7 0.1 6.8e-08 32.8 0.0 5.0 1 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 KUM67045.1 - 3.8e-16 57.8 0.7 3.5e-06 26.8 0.0 7.0 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.13 KUM67045.1 - 1.5e-08 34.4 0.0 0.0021 17.6 0.0 3.9 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.8 KUM67045.1 - 5.9e-05 23.2 0.0 1.5 9.0 0.0 4.6 4 1 0 4 4 4 1 V-ATPase subunit H HEAT_PBS PF03130.16 KUM67045.1 - 0.031 14.9 1.4 1.5 9.8 0.0 4.1 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Gcn1_N PF12074.8 KUM67045.1 - 0.092 12.0 0.0 14 4.8 0.0 2.3 2 0 0 2 2 2 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal RICTOR_V PF14668.6 KUM67045.1 - 0.094 13.0 3.5 1.5 9.1 0.0 4.3 4 2 1 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 STAG PF08514.11 KUM67046.1 - 1.8e-40 137.4 4.0 2.9e-39 133.5 2.6 3.1 2 0 0 2 2 2 1 STAG domain YL1 PF05764.13 KUM67046.1 - 0.0029 17.8 10.3 0.0029 17.8 10.3 4.4 4 1 0 4 4 4 1 YL1 nuclear protein MIF4G PF02854.19 KUM67046.1 - 0.015 15.0 0.1 0.077 12.6 0.0 2.2 2 1 0 2 2 2 0 MIF4G domain Nipped-B_C PF12830.7 KUM67046.1 - 0.068 13.1 0.0 0.23 11.4 0.0 1.9 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus HEAT_2 PF13646.6 KUM67046.1 - 0.21 12.0 2.0 0.58 10.6 0.2 2.8 3 0 0 3 3 3 0 HEAT repeats HsbA PF12296.8 KUM67046.1 - 0.73 10.3 4.3 4.9 7.6 1.5 3.2 2 0 0 2 2 2 0 Hydrophobic surface binding protein A BLOC1_2 PF10046.9 KUM67046.1 - 4 7.8 7.5 0.62 10.4 0.6 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran PF00005.27 KUM67047.1 - 1.5e-17 64.4 0.0 2.9e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KUM67047.1 - 5.2e-12 46.0 5.0 1.1e-11 44.9 5.0 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KUM67047.1 - 9.7e-05 21.9 0.0 0.024 14.1 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KUM67047.1 - 0.00064 19.4 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 KUM67047.1 - 0.052 13.6 0.1 0.088 12.9 0.1 1.3 1 0 0 1 1 1 0 Dynamin family DUF423 PF04241.15 KUM67047.1 - 4.5 7.5 5.8 12 6.1 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF423) UreD PF01774.17 KUM67048.1 - 4.5e-78 262.0 0.0 6e-78 261.6 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein zf-CCCH_2 PF14608.6 KUM67049.1 - 0.081 13.4 0.2 0.081 13.4 0.2 3.2 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger DUF1764 PF08576.10 KUM67050.1 - 0.17 12.8 3.7 8 7.4 0.4 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Cyclin_N PF00134.23 KUM67051.1 - 1.6e-10 40.8 0.1 6.4e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KUM67051.1 - 0.11 12.9 0.6 0.4 11.1 0.1 2.2 2 1 0 2 2 2 0 Cyclin C-terminal domain adh_short_C2 PF13561.6 KUM67053.1 - 4.1e-54 183.6 0.1 5.3e-54 183.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KUM67053.1 - 4.1e-46 156.9 0.1 5.1e-46 156.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KUM67053.1 - 3.4e-15 56.4 0.2 5.2e-15 55.8 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KUM67053.1 - 0.00017 21.2 0.1 0.00025 20.6 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HATPase_c PF02518.26 KUM67053.1 - 0.0054 17.2 0.0 0.0095 16.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NAD_binding_2 PF03446.15 KUM67053.1 - 0.022 15.0 0.0 0.093 12.9 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GCP_N_terminal PF17681.1 KUM67054.1 - 4e-35 121.9 0.1 6.8e-35 121.2 0.1 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KUM67054.1 - 1.8e-19 70.3 0.0 3.1e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal DEAD PF00270.29 KUM67056.1 - 8.2e-18 64.8 0.0 1.7e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KUM67056.1 - 2.7e-11 43.8 0.0 8.4e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KUM67056.1 - 3.8e-06 27.2 0.0 1.8e-05 25.1 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.16 KUM67056.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein GST_N_2 PF13409.6 KUM67057.1 - 5.2e-24 84.3 0.0 1.3e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KUM67057.1 - 5.6e-18 64.7 0.2 2e-17 63.0 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KUM67057.1 - 2e-07 31.1 0.1 4e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KUM67057.1 - 7.9e-06 26.2 0.1 0.00034 20.9 0.1 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KUM67057.1 - 0.00027 21.1 0.0 0.00054 20.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KUM67057.1 - 0.0047 17.5 0.0 0.008 16.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KUM67057.1 - 0.017 14.9 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain QIL1 PF15884.5 KUM67057.1 - 0.039 14.5 0.0 0.4 11.3 0.0 2.3 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 Mito_carr PF00153.27 KUM67058.1 - 1.8e-68 226.5 4.0 2.2e-22 78.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KUM67058.1 - 1.1e-06 27.8 0.2 2.7e-06 26.5 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KUM67058.1 - 2.9e-05 23.4 0.2 6e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KUM67058.1 - 0.0001 22.7 0.0 0.00019 21.8 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KUM67058.1 - 0.00025 20.7 0.4 0.00076 19.2 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KUM67058.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair ThiF PF00899.21 KUM67060.1 - 9e-110 365.8 0.0 1.7e-72 243.7 0.0 2.3 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KUM67060.1 - 1.6e-97 326.4 0.8 6.5e-97 324.4 0.4 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KUM67060.1 - 3.3e-31 107.8 0.1 6.8e-31 106.8 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 KUM67060.1 - 4.7e-30 103.6 0.2 9.8e-30 102.6 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KUM67060.1 - 6.8e-26 90.2 0.6 2.1e-25 88.7 0.6 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Penicillium_freii-ASM151392v1/GCA_001513925.1_ASM151392v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Penicillium_freii-ASM151392v1/GCA_001513925.1_ASM151392v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Penicillium_freii-ASM151392v1/GCA_001513925.1_ASM151392v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Penicillium_freii-ASM151392v1/GCA_001513925.1_ASM151392v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 02:54:37 2019 # [ok]